# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SR-25 PF10500.4 KOS12392.1 - 0.06 12.8 12.6 0.085 12.3 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 KOS12392.1 - 6.2 4.5 14.5 7.9 4.1 10.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Transp_cyt_pur PF02133.10 KOS12393.1 - 0.013 14.0 4.9 0.015 13.8 3.4 1.2 1 1 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Alk_phosphatase PF00245.15 KOS12394.1 - 1.9e-55 188.2 2.9 7.5e-41 140.1 0.7 2.0 1 1 1 2 2 2 2 Alkaline phosphatase Alk_phosphatase PF00245.15 KOS12395.1 - 4.9e-09 35.3 0.0 5.2e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase NPP1 PF05630.6 KOS12395.1 - 0.084 12.5 0.3 0.097 12.3 0.2 1.1 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Transp_cyt_pur PF02133.10 KOS12396.1 - 9.5e-24 83.7 34.3 1.5e-23 83.1 23.8 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YuiB PF14068.1 KOS12396.1 - 0.28 11.5 9.9 1.1 9.5 1.0 3.3 2 1 0 2 2 2 0 Putative membrane protein Amino_oxidase PF01593.19 KOS12399.1 - 6.4e-61 206.7 0.1 9.5e-61 206.2 0.0 1.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS12399.1 - 2.8e-13 49.6 0.1 9.3e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS12399.1 - 7.2e-08 31.7 0.2 0.00013 21.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KOS12399.1 - 2.9e-06 27.4 0.4 0.00097 19.2 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS12399.1 - 1.6e-05 24.7 0.6 0.011 15.5 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 KOS12399.1 - 3.3e-05 23.0 0.2 5.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KOS12399.1 - 7.2e-05 21.8 0.5 0.00014 20.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KOS12399.1 - 0.00011 22.5 0.6 0.00033 20.9 0.0 2.2 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS12399.1 - 0.001 17.6 0.1 0.023 13.2 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 KOS12399.1 - 0.0028 16.6 0.0 0.023 13.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KOS12399.1 - 0.0056 16.5 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS12399.1 - 0.015 14.4 0.1 0.031 13.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 KOS12399.1 - 0.076 12.0 0.2 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KOS12399.1 - 0.14 10.9 0.1 2 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A LIP PF03583.9 KOS12400.1 - 8.8e-69 231.8 0.1 1.1e-68 231.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS12400.1 - 0.0018 18.0 0.0 0.0035 17.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS12400.1 - 0.051 12.7 0.2 6.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Alk_phosphatase PF00245.15 KOS12401.1 - 3.8e-05 22.5 0.0 4.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Pec_lyase_C PF00544.14 KOS12401.1 - 0.2 11.0 3.3 0.24 10.8 2.3 1.2 1 0 0 1 1 1 0 Pectate lyase RVT_1 PF00078.22 KOS12402.1 - 1.1e-19 70.7 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LIP PF03583.9 KOS12404.1 - 7.5e-70 235.4 0.1 9.8e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS12404.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS12404.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS12404.1 - 0.041 13.0 0.2 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KOS12404.1 - 0.044 13.3 0.0 0.16 11.5 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Amino_oxidase PF01593.19 KOS12405.1 - 2.7e-62 211.3 0.1 3.7e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS12405.1 - 2.9e-13 49.6 0.1 9.3e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS12405.1 - 3.1e-08 32.9 0.1 0.00013 21.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KOS12405.1 - 2.3e-06 27.8 0.5 0.00097 19.2 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS12405.1 - 1.8e-05 24.5 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 KOS12405.1 - 3.4e-05 23.0 0.2 5.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KOS12405.1 - 5.6e-05 22.1 0.8 0.00014 20.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KOS12405.1 - 7.9e-05 22.9 0.2 0.00033 20.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS12405.1 - 0.0014 17.1 0.0 0.023 13.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KOS12405.1 - 0.0048 15.8 0.0 0.023 13.6 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KOS12405.1 - 0.0049 16.7 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS12405.1 - 0.015 14.3 0.1 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KOS12405.1 - 0.077 12.0 0.4 0.17 10.9 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Transp_cyt_pur PF02133.10 KOS12406.1 - 2.6e-25 88.8 39.0 4.1e-25 88.2 27.1 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Alk_phosphatase PF00245.15 KOS12407.1 - 3.8e-05 22.5 0.0 4.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Pec_lyase_C PF00544.14 KOS12407.1 - 0.2 11.0 3.3 0.24 10.8 2.3 1.2 1 0 0 1 1 1 0 Pectate lyase ABC_membrane PF00664.18 KOS12408.1 - 2.5e-37 128.7 19.1 2e-22 79.9 6.7 4.0 3 2 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS12408.1 - 8.7e-20 71.4 0.0 2.5e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS12408.1 - 0.00068 19.6 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KOS12408.1 - 0.0048 16.1 0.1 0.47 9.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KOS12408.1 - 0.016 15.3 0.4 0.31 11.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 KOS12408.1 - 0.024 14.5 0.0 0.08 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KOS12408.1 - 0.03 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 KOS12408.1 - 0.041 13.3 0.2 0.081 12.3 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KOS12408.1 - 0.051 13.3 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 KOS12408.1 - 0.082 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KOS12408.1 - 0.092 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS12408.1 - 0.13 11.9 1.3 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KOS12408.1 - 0.66 10.2 0.0 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PAC2 PF09754.4 KOS12409.1 - 1.3e-23 84.0 0.0 6.8e-23 81.6 0.0 1.9 1 1 0 1 1 1 1 PAC2 family MutS_V PF00488.16 KOS12410.1 - 1.4e-76 257.0 0.0 2.5e-76 256.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS12410.1 - 2e-45 155.1 5.9 3.2e-45 154.4 4.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KOS12410.1 - 2.2e-22 79.2 0.0 3.9e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KOS12410.1 - 1.5e-11 44.5 0.0 5e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 KOS12410.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS12410.1 - 0.047 14.0 0.2 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ICAT PF06384.6 KOS12410.1 - 0.063 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT NADHdh PF00146.16 KOS12411.1 - 1.4e-115 385.6 29.6 1.4e-115 385.6 20.5 1.5 2 0 0 2 2 2 1 NADH dehydrogenase COX2 PF00116.15 KOS12411.1 - 4.2e-34 116.9 0.1 1e-33 115.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.10 KOS12411.1 - 5.3e-22 77.5 0.1 5.3e-22 77.5 0.1 4.5 4 0 0 4 4 4 1 Cytochrome C oxidase subunit II, transmembrane domain COX1 PF00115.15 KOS12412.1 - 1.2e-34 119.7 6.9 1.4e-34 119.5 4.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Oxidored_q1 PF00361.15 KOS12413.1 - 9.4e-74 248.0 24.4 9.4e-74 248.0 16.9 4.3 3 1 0 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 KOS12413.1 - 1.1e-20 72.9 7.3 1.1e-20 72.9 5.1 3.3 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.6 KOS12413.1 - 1.3e-10 40.9 9.2 1.3e-10 40.9 6.4 5.6 5 1 0 5 5 5 1 NADH dehydrogenase subunit 5 C-terminus Polysacc_deac_1 PF01522.16 KOS12415.1 - 1.8e-34 118.0 0.0 9.9e-30 102.7 0.0 2.8 3 0 0 3 3 3 2 Polysaccharide deacetylase DUF1682 PF07946.9 KOS12416.1 - 2.8e-57 193.9 0.0 3.2e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4029 PF13221.1 KOS12416.1 - 0.1 13.0 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) Ribonuclease_T2 PF00445.13 KOS12417.1 - 5.9e-35 120.6 0.5 9.3e-35 119.9 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Chalcone PF02431.10 KOS12418.1 - 1.7e-32 112.4 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF581 PF04570.9 KOS12419.1 - 0.41 9.9 2.6 0.59 9.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Zn_clus PF00172.13 KOS12419.1 - 8.9 6.3 7.0 0.78 9.6 0.5 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.17 KOS12420.1 - 1.6e-15 57.4 0.0 3.2e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KOS12420.1 - 1.6e-14 53.9 0.0 1.3e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KOS12420.1 - 0.0005 19.6 0.0 0.00086 18.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like COG6 PF06419.6 KOS12421.1 - 5.5e-59 199.8 0.0 1.4e-58 198.5 0.0 1.6 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 TraI PF07057.6 KOS12421.1 - 0.51 10.3 4.8 0.38 10.7 0.2 2.5 2 0 0 2 2 2 0 DNA helicase TraI Arrestin_N PF00339.24 KOS12422.1 - 0.091 12.5 0.2 3.7 7.3 0.1 2.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Cu-oxidase_2 PF07731.9 KOS12423.1 - 5.1e-27 94.0 0.2 6.9e-27 93.6 0.2 1.2 1 0 0 1 1 1 1 Multicopper oxidase HVSL PF09749.4 KOS12423.1 - 0.012 14.6 0.1 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein Cu-oxidase PF00394.17 KOS12424.1 - 1.4e-12 47.7 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Peptidase_M24 PF00557.19 KOS12425.1 - 1.7e-42 145.3 0.1 2.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 KOS12425.1 - 0.011 15.8 1.2 0.017 15.1 0.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Vasculin PF15337.1 KOS12425.1 - 0.21 12.0 1.9 2.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Spt5_N PF11942.3 KOS12425.1 - 5 7.8 11.8 1.2 9.7 1.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Rhodanese PF00581.15 KOS12426.1 - 1.2e-18 67.5 0.0 1.8e-10 41.1 0.0 2.6 2 1 0 2 2 2 2 Rhodanese-like domain Abhydrolase_6 PF12697.2 KOS12427.1 - 4.7e-26 92.0 0.0 9e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS12427.1 - 2.9e-13 49.7 0.0 3.8e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS12427.1 - 9.3e-13 48.2 0.0 1.4e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 KOS12427.1 - 5.3e-10 39.2 0.0 9.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KOS12427.1 - 2.2e-06 27.4 0.0 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 KOS12427.1 - 0.0001 22.6 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 KOS12427.1 - 0.00064 19.0 0.1 0.0013 18.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 KOS12427.1 - 0.0038 16.1 0.0 0.0064 15.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KOS12427.1 - 0.0047 15.7 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DUF900 PF05990.7 KOS12427.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.15 KOS12427.1 - 0.13 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase 6PF2K PF01591.13 KOS12428.1 - 1.1e-74 250.2 0.0 1.6e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KOS12428.1 - 2e-31 109.2 0.0 9.4e-31 107.0 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KOS12428.1 - 6.1e-11 42.3 0.1 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS12428.1 - 6.9e-05 23.6 0.0 0.00063 20.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS12428.1 - 0.003 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 KOS12428.1 - 0.0035 16.6 0.0 0.0085 15.3 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 GBP PF02263.14 KOS12428.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Methyltransf_32 PF13679.1 KOS12428.1 - 0.093 12.4 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Macro PF01661.16 KOS12429.1 - 2.4e-38 130.6 0.1 3.3e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Macro domain Acetyltransf_1 PF00583.19 KOS12431.1 - 8.4e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS12431.1 - 1.5e-09 37.8 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS12431.1 - 9e-06 25.8 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS12431.1 - 0.0022 17.8 0.0 0.0034 17.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS12431.1 - 0.0048 16.6 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein UQ_con PF00179.21 KOS12432.1 - 2.6e-37 127.3 0.0 3.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Methyltransf_23 PF13489.1 KOS12433.1 - 2.1e-09 37.2 0.1 3.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS12433.1 - 8.4e-09 35.8 0.0 3.3e-08 33.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS12433.1 - 8.3e-05 23.1 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS12433.1 - 0.00033 20.9 0.0 0.00095 19.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12433.1 - 0.00051 20.0 0.1 0.0011 18.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS12433.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KOS12433.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12433.1 - 0.0065 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF72 PF01904.13 KOS12433.1 - 0.025 14.3 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 FmrO PF07091.6 KOS12433.1 - 0.059 12.3 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) LIP PF03583.9 KOS12434.1 - 1.7e-64 217.8 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS12434.1 - 5.5e-07 29.4 0.0 2.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS12434.1 - 0.0054 15.9 1.2 0.92 8.6 0.1 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KOS12434.1 - 0.0068 16.3 0.1 0.026 14.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Polysacc_deac_1 PF01522.16 KOS12435.1 - 2.4e-13 49.7 0.0 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3414 PF11894.3 KOS12436.1 - 3.9e-05 20.7 0.2 8.4e-05 19.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Fer4_15 PF13459.1 KOS12436.1 - 0.019 15.4 1.4 0.066 13.7 1.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain Nucleoporin_C PF03177.9 KOS12437.1 - 1.2e-48 166.0 1.1 1.6e-48 165.6 0.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KOS12437.1 - 4e-12 45.5 0.0 7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like USP7_ICP0_bdg PF12436.3 KOS12438.1 - 1.5e-81 273.3 2.4 2.2e-81 272.7 1.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KOS12438.1 - 1.3e-65 220.7 6.0 1.9e-62 210.4 0.6 2.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KOS12438.1 - 9.9e-57 192.0 0.3 1.5e-56 191.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS12438.1 - 3.1e-30 105.6 0.0 5.3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KOS12438.1 - 8.6e-11 42.1 0.1 1.4e-07 31.7 0.0 3.4 2 1 0 2 2 2 2 MATH domain RNA_pol_Rpb1_5 PF04998.12 KOS12439.1 - 9.6e-84 280.9 0.0 2.2e-83 279.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KOS12439.1 - 6.6e-60 201.8 0.0 1.4e-59 200.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KOS12439.1 - 2.1e-36 125.0 0.0 4.4e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KOS12439.1 - 8.3e-30 104.1 0.1 2e-25 89.7 0.0 3.8 3 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KOS12439.1 - 2.7e-20 72.1 0.0 9.4e-20 70.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Romo1 PF10247.4 KOS12440.1 - 1.6e-23 82.6 12.2 2e-23 82.3 8.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 ABC2_membrane_4 PF12730.2 KOS12440.1 - 0.027 13.6 0.0 0.032 13.3 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Tim17 PF02466.14 KOS12440.1 - 0.26 11.3 6.9 2.5 8.1 4.8 2.0 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family CYSTM PF12734.2 KOS12440.1 - 1.4 9.0 3.8 2.2 8.3 2.6 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance ThiF PF00899.16 KOS12441.1 - 3.6e-35 120.7 0.0 5.9e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family SPT6_acidic PF14632.1 KOS12441.1 - 0.04 14.0 1.0 0.081 13.0 0.7 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 FAD_binding_3 PF01494.14 KOS12441.1 - 0.16 10.9 0.2 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PIG-X PF08320.7 KOS12442.1 - 3.9e-12 45.8 0.1 7.2e-06 25.4 0.0 2.9 2 1 0 2 2 2 2 PIG-X / PBN1 SNARE PF05739.14 KOS12443.1 - 9.3e-18 63.6 0.8 9.3e-18 63.6 0.6 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KOS12443.1 - 1.4e-13 50.8 4.0 1.4e-13 50.8 2.8 2.4 2 1 0 2 2 2 1 Syntaxin HalX PF08663.5 KOS12443.1 - 0.025 14.5 0.3 0.085 12.8 0.2 2.0 1 0 0 1 1 1 0 HalX domain DUF1664 PF07889.7 KOS12443.1 - 0.079 12.7 2.9 0.5 10.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KOS12443.1 - 0.16 12.1 5.0 1.2 9.3 0.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 KOS12443.1 - 0.18 11.7 1.1 0.82 9.6 0.0 2.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF148 PF02520.12 KOS12443.1 - 0.3 10.8 10.1 2.4 7.9 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF148 Syntaxin-6_N PF09177.6 KOS12443.1 - 2.6 8.4 6.3 4.4 7.7 0.6 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ATG16 PF08614.6 KOS12443.1 - 4 7.2 17.9 1.1 8.9 6.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SseC PF04888.7 KOS12443.1 - 7.5 5.7 11.9 5.3 6.2 3.2 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Cys_Met_Meta_PP PF01053.15 KOS12444.1 - 2.9e-23 81.8 0.0 5.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS12444.1 - 0.00041 19.4 0.0 0.0007 18.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Rnk_N PF14760.1 KOS12444.1 - 0.044 13.8 3.1 0.46 10.5 0.1 2.5 2 0 0 2 2 2 0 Rnk N-terminus GMP_synt_C PF00958.17 KOS12445.1 - 1.9e-40 136.4 0.1 1.2e-39 133.9 0.1 2.2 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 KOS12445.1 - 1.6e-37 128.8 0.0 3.2e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 KOS12445.1 - 3e-12 45.9 0.1 1.2e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KOS12445.1 - 1.7e-09 37.4 0.0 3.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 KOS12445.1 - 0.00014 21.3 0.0 0.00034 20.1 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 KOS12445.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KOS12445.1 - 0.00018 20.2 0.2 0.00037 19.1 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 KOS12445.1 - 0.0005 19.4 0.0 0.0053 16.0 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 KOS12445.1 - 0.0092 15.0 0.1 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Arginosuccinate synthase DUF2392 PF10288.4 KOS12445.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) RRM_1 PF00076.17 KOS12446.1 - 7e-14 51.2 0.0 1.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS12446.1 - 2.6e-10 40.1 0.0 4.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS12446.1 - 2.2e-07 30.6 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KOS12446.1 - 9.9e-05 22.7 6.3 9.9e-05 22.7 4.3 2.5 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Androgen_recep PF02166.11 KOS12446.1 - 1.3 7.8 12.7 0.052 12.4 3.9 1.9 2 0 0 2 2 2 0 Androgen receptor Histone PF00125.19 KOS12447.1 - 1.3e-30 105.3 0.4 2e-30 104.7 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KOS12447.1 - 9e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS12447.1 - 0.0073 16.3 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KOS12447.1 - 0.013 14.7 0.9 0.02 14.1 0.6 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KOS12447.1 - 0.019 14.7 0.1 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TP_methylase PF00590.15 KOS12448.1 - 8e-40 136.7 0.8 8e-40 136.7 0.6 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KOS12448.1 - 3.9e-12 46.3 0.0 1.2e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 KOS12448.1 - 0.00011 21.0 0.0 0.00021 20.1 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 KOS12448.1 - 0.00013 21.1 0.1 0.001 18.3 0.0 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Peptidase_M16_C PF05193.16 KOS12449.1 - 1.3e-19 70.5 0.0 1.1e-13 51.3 0.0 3.3 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KOS12449.1 - 4.1e-07 29.8 0.1 2.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Citrate_synt PF00285.16 KOS12450.1 - 4.5e-18 65.1 0.0 7.4e-16 57.8 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KOS12450.1 - 1.4e-14 54.0 0.1 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KOS12450.1 - 9.8e-12 45.2 0.0 2.2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 KOS12450.1 - 1.5e-06 27.8 0.0 5e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 KOS12450.1 - 1.9e-05 24.1 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 KOS12450.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain WD40 PF00400.27 KOS12451.1 - 4.6e-19 67.5 0.6 0.0056 16.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat SAM_decarbox PF01536.11 KOS12452.1 - 6.7e-88 294.5 0.0 1.8e-87 293.1 0.0 1.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Sdh_cyt PF01127.17 KOS12453.1 - 4.2e-22 78.2 3.6 5.6e-22 77.8 2.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1744 PF08490.7 KOS12454.1 - 2.1e-108 362.4 0.0 3.8e-108 361.5 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KOS12454.1 - 1.2e-63 214.9 0.1 2e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KOS12454.1 - 2.3e-19 69.5 0.1 8.3e-19 67.7 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KOS12454.1 - 4.4e-09 36.1 0.1 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KOS12454.1 - 0.00063 19.5 0.1 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 KOS12454.1 - 0.14 11.4 2.1 0.31 10.3 1.5 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Gly-rich_Ago1 PF12764.2 KOS12454.1 - 4.3 8.0 6.6 1.4 9.6 2.0 2.1 2 0 0 2 2 2 0 Glycine-rich region of argonaut Xan_ur_permease PF00860.15 KOS12455.1 - 1.5e-23 82.9 22.9 5.9e-23 80.9 15.1 2.1 1 1 0 1 1 1 1 Permease family Ldr_toxin PF13940.1 KOS12455.1 - 0.13 12.0 1.9 0.69 9.7 1.4 2.3 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system RVT_1 PF00078.22 KOS12456.1 - 6.3e-13 48.5 0.0 2.7e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.19 KOS12456.1 - 5.2e-12 45.0 7.9 1.7e-09 36.7 2.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter AAA_27 PF13514.1 KOS12456.1 - 1.7 6.1 4.9 1.6 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2296 PF10058.4 KOS12457.1 - 7.2e-23 80.1 0.2 1.1e-22 79.5 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) PSI_PsaF PF02507.10 KOS12457.1 - 0.18 11.3 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III DUF1675 PF07897.6 KOS12457.1 - 0.23 11.2 3.8 0.43 10.4 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ArsC PF03960.10 KOS12459.1 - 1.3e-30 105.6 0.0 1.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.19 KOS12459.1 - 5.5e-05 23.0 0.0 0.00028 20.7 0.0 2.0 1 1 1 2 2 2 1 Glutaredoxin GAF_2 PF13185.1 KOS12459.1 - 0.092 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 GAF domain Beach PF02138.13 KOS12461.1 - 8.7e-100 333.6 0.0 1.2e-99 333.1 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KOS12461.1 - 7.7e-08 31.9 6.3 1.2e-06 28.1 0.2 4.5 3 1 0 3 3 3 1 WD domain, G-beta repeat PH_BEACH PF14844.1 KOS12461.1 - 3e-05 23.7 0.0 6.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE_2 PF02318.11 KOS12461.1 - 0.039 13.8 5.9 0.1 12.4 4.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Laminin_G_3 PF13385.1 KOS12461.1 - 0.052 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.16 KOS12461.1 - 1.1 9.2 9.8 3.3 7.6 6.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF2326 PF10088.4 KOS12461.1 - 1.3 8.6 0.0 2.4 7.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) Spc97_Spc98 PF04130.8 KOS12462.1 - 1.4e-105 353.6 1.6 6.7e-105 351.4 0.8 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family WD40 PF00400.27 KOS12463.1 - 3.3e-39 131.3 1.6 2.3e-07 30.4 0.0 6.6 5 1 2 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KOS12463.1 - 2.8e-06 27.1 0.2 0.00023 20.9 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A UcrQ PF02939.11 KOS12464.1 - 2.7e-26 91.1 1.5 3.3e-26 90.9 1.0 1.0 1 0 0 1 1 1 1 UcrQ family ParA PF10609.4 KOS12465.1 - 7.2e-35 118.7 0.0 1.4e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KOS12465.1 - 1.3e-11 44.2 0.0 2.9e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KOS12465.1 - 0.00014 21.0 0.1 0.00038 19.6 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KOS12465.1 - 0.00024 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KOS12465.1 - 0.0019 17.4 0.0 0.92 8.6 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 KOS12465.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS12465.1 - 0.016 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MipZ PF09140.6 KOS12465.1 - 0.059 12.4 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ ArgK PF03308.11 KOS12465.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein YhjQ PF06564.7 KOS12465.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 KOS12465.1 - 0.17 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KOS12465.1 - 0.18 12.6 0.1 1.2 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain 5_nucleotid_C PF02872.13 KOS12467.1 - 1.2e-28 100.0 0.0 4.3e-27 94.9 0.0 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KOS12467.1 - 0.041 13.2 2.8 0.62 9.4 1.9 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase ABC2_membrane PF01061.19 KOS12468.1 - 1.5e-161 533.9 125.5 2.1e-44 151.2 16.8 5.7 6 0 0 6 6 5 4 ABC-2 type transporter ABC_tran PF00005.22 KOS12468.1 - 1.9e-75 251.6 0.0 1.3e-17 64.4 0.0 5.7 6 0 0 6 6 5 4 ABC transporter PDR_CDR PF06422.7 KOS12468.1 - 2.4e-49 165.2 13.7 2.4e-24 84.9 0.0 5.1 5 0 0 5 5 4 3 CDR ABC transporter ABC_trans_N PF14510.1 KOS12468.1 - 8.1e-22 77.1 0.0 9.5e-12 44.8 0.0 2.7 2 0 0 2 2 2 2 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KOS12468.1 - 1.9e-15 56.7 0.2 0.0059 16.0 0.2 5.6 5 1 0 5 5 5 3 AAA domain DUF258 PF03193.11 KOS12468.1 - 1.8e-12 46.7 0.1 0.00011 21.3 0.0 3.2 4 0 0 4 4 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KOS12468.1 - 2.7e-11 43.7 1.0 0.032 14.3 0.0 5.2 4 2 0 4 4 4 2 AAA domain cobW PF02492.14 KOS12468.1 - 9.7e-11 41.4 0.8 0.0026 17.2 0.0 4.2 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KOS12468.1 - 1.6e-10 41.2 4.4 0.0063 16.5 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 KOS12468.1 - 6.8e-09 36.5 0.0 0.2 12.4 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KOS12468.1 - 9.9e-08 32.3 0.1 0.23 11.7 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 KOS12468.1 - 1.2e-07 31.3 1.4 5.4 6.8 0.0 4.7 4 0 0 4 4 4 0 Part of AAA domain AAA_21 PF13304.1 KOS12468.1 - 1.8e-07 31.4 0.0 2 8.2 0.0 4.8 5 0 0 5 5 4 2 AAA domain NACHT PF05729.7 KOS12468.1 - 2.5e-07 30.4 0.4 0.51 9.9 0.0 4.5 4 0 0 4 4 4 2 NACHT domain AAA_29 PF13555.1 KOS12468.1 - 2.9e-07 29.9 6.1 0.039 13.4 0.1 4.3 4 0 0 4 4 4 2 P-loop containing region of AAA domain UPF0079 PF02367.12 KOS12468.1 - 3.7e-07 29.7 7.0 0.21 11.2 0.2 4.4 4 0 0 4 4 4 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KOS12468.1 - 2.4e-06 28.0 0.0 0.88 10.0 0.0 4.3 4 0 0 4 4 4 1 Miro-like protein SMC_N PF02463.14 KOS12468.1 - 2.9e-06 26.7 0.0 0.27 10.4 0.0 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KOS12468.1 - 4e-05 23.6 2.4 1.9 8.4 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.1 KOS12468.1 - 6.2e-05 22.2 0.0 8.4 5.3 0.0 4.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.1 KOS12468.1 - 6.4e-05 22.8 0.1 3.2 7.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 KOS12468.1 - 6.4e-05 23.1 0.9 12 6.1 0.0 4.6 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KOS12468.1 - 8.6e-05 22.4 0.2 2.7 7.9 0.0 4.1 4 0 0 4 4 4 2 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.2 KOS12468.1 - 0.00014 21.0 101.2 0.00018 20.6 6.5 6.2 4 3 1 5 5 4 3 ABC-2 family transporter protein SbcCD_C PF13558.1 KOS12468.1 - 0.00033 20.5 0.1 6.4 6.7 0.0 4.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KOS12468.1 - 0.00046 19.7 4.0 9.8 5.5 0.0 4.6 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KOS12468.1 - 0.00089 19.6 0.4 2.1 8.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KOS12468.1 - 0.0027 16.8 0.2 3.7 6.5 0.0 3.3 4 0 0 4 4 3 0 Zeta toxin PduV-EutP PF10662.4 KOS12468.1 - 0.0028 17.1 4.6 2.2 7.7 0.1 3.7 4 0 0 4 4 4 2 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KOS12468.1 - 0.0038 16.2 0.1 6 5.7 0.0 3.2 3 0 0 3 3 3 0 Septin AAA_10 PF12846.2 KOS12468.1 - 0.004 16.6 2.7 6.2 6.1 0.0 4.2 4 1 0 4 4 4 0 AAA-like domain Arch_ATPase PF01637.13 KOS12468.1 - 0.0047 16.6 0.0 17 4.9 0.0 3.8 4 0 0 4 4 3 0 Archaeal ATPase AAA_30 PF13604.1 KOS12468.1 - 0.01 15.4 5.5 11 5.5 0.3 4.2 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.1 KOS12468.1 - 0.014 15.0 3.8 18 4.8 0.1 4.2 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.20 KOS12468.1 - 0.023 14.2 0.0 28 4.1 0.0 3.7 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KOS12468.1 - 0.041 14.0 0.1 26 5.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase T2SE PF00437.15 KOS12468.1 - 0.048 12.5 1.8 28 3.5 0.1 4.1 4 1 0 5 5 5 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 KOS12468.1 - 0.19 10.2 1.0 5.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FeoB_N PF02421.13 KOS12468.1 - 0.26 10.5 0.9 24 4.1 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B Pox_A32 PF04665.7 KOS12468.1 - 0.42 9.8 1.0 55 2.9 0.0 3.4 3 0 0 3 3 3 0 Poxvirus A32 protein Dynamin_N PF00350.18 KOS12468.1 - 0.49 10.1 0.0 42 3.8 0.0 2.7 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 KOS12468.1 - 0.64 9.7 1.0 86 2.7 0.0 3.7 5 0 0 5 5 3 0 NTPase AAA_5 PF07728.9 KOS12468.1 - 0.88 9.2 4.7 24 4.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KOS12468.1 - 3.3 7.1 6.9 20 4.5 0.4 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain UQ_con PF00179.21 KOS12469.1 - 1.1e-24 86.5 0.0 1.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KOS12469.1 - 0.093 12.6 0.1 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF2340 PF10209.4 KOS12470.1 - 1.2e-40 138.4 0.0 2.4e-40 137.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) NIF PF03031.13 KOS12471.1 - 2.1e-50 170.4 0.0 7.6e-50 168.6 0.0 1.9 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase PGI PF00342.14 KOS12472.1 - 7.7e-213 707.2 0.1 8.9e-213 707.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 KOS12473.1 - 2.3e-61 207.2 0.0 3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12473.1 - 1.2e-29 103.2 0.0 1.7e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12473.1 - 3.2e-05 23.0 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS12473.1 - 0.018 14.8 0.2 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3172 PF11371.3 KOS12473.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) FIIND PF13553.1 KOS12473.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Function to find XPG_N PF00752.12 KOS12474.1 - 1.5e-29 102.2 0.0 3.4e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS12474.1 - 7.4e-26 90.0 0.0 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KOS12474.1 - 8e-06 25.5 0.0 2.9e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 XPG domain containing SKI PF01202.17 KOS12475.1 - 4.9e-12 45.9 0.0 5.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KOS12475.1 - 7.3e-05 22.6 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS12475.1 - 0.0049 17.6 0.0 0.0064 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS12475.1 - 0.024 14.9 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.21 KOS12475.1 - 0.024 14.2 0.1 0.061 12.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 APS_kinase PF01583.15 KOS12475.1 - 0.031 13.9 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase SNARE_assoc PF09335.6 KOS12476.1 - 7.2e-17 61.7 0.3 1.5e-16 60.7 0.1 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein NDUF_B8 PF05821.6 KOS12477.1 - 1.1e-05 25.1 0.2 1.1e-05 25.1 0.2 1.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) HPIP PF15226.1 KOS12478.1 - 0.085 12.9 0.3 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Syntaxin-6_N PF09177.6 KOS12479.1 - 7.7e-18 64.6 2.8 7.7e-18 64.6 1.9 2.3 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KOS12479.1 - 1.3e-08 34.3 4.6 1.3e-08 34.3 3.2 2.8 4 0 0 4 4 4 1 SNARE domain DUF948 PF06103.6 KOS12479.1 - 0.0062 16.3 5.4 1.5 8.6 0.3 3.4 2 2 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Interferon PF00143.14 KOS12479.1 - 0.016 15.1 3.6 0.017 15.0 1.9 1.6 1 1 0 1 1 1 0 Interferon alpha/beta domain FlaC_arch PF05377.6 KOS12479.1 - 0.017 14.9 1.0 0.92 9.4 0.1 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Chorismate_bind PF00425.13 KOS12479.1 - 0.081 12.2 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 chorismate binding enzyme Allexi_40kDa PF05549.6 KOS12479.1 - 0.12 11.6 4.6 0.076 12.2 1.4 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.7 KOS12479.1 - 0.14 11.9 6.2 0.27 11.0 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.4 KOS12479.1 - 0.35 9.5 6.7 0.19 10.4 2.1 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HisKA_3 PF07730.8 KOS12479.1 - 0.41 11.0 10.6 2.9 8.2 0.4 2.8 2 1 1 3 3 3 0 Histidine kinase Mnd1 PF03962.10 KOS12479.1 - 0.45 10.1 6.1 0.18 11.4 1.8 1.9 1 1 1 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 KOS12479.1 - 0.48 10.1 8.8 0.3 10.8 0.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 KOS12479.1 - 0.48 9.9 7.8 0.58 9.6 0.7 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF607 PF04678.8 KOS12479.1 - 1.1 9.2 5.0 4.9 7.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Cortex-I_coil PF09304.5 KOS12479.1 - 1.6 8.7 11.7 5.4 7.1 0.8 2.3 1 1 0 2 2 2 0 Cortexillin I, coiled coil Baculo_PEP_C PF04513.7 KOS12479.1 - 3.8 7.3 8.2 26 4.6 1.8 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KOS12479.1 - 4.3 7.6 8.7 5.3 7.3 0.4 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 KOS12479.1 - 5 6.9 11.3 6 6.7 0.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_DNAp_acc PF04929.7 KOS12480.1 - 1 8.2 3.4 1.5 7.7 2.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BUD22 PF09073.5 KOS12480.1 - 2.4 7.1 9.5 4.9 6.1 6.6 1.4 1 0 0 1 1 1 0 BUD22 Auxin_canalis PF05703.6 KOS12480.1 - 2.5 7.8 9.5 2.2 8.0 5.0 2.0 2 0 0 2 2 2 0 Auxin canalisation MCM PF00493.18 KOS12482.1 - 5.6e-140 465.8 0.1 8.2e-140 465.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KOS12482.1 - 2.9e-32 111.8 30.3 2.9e-32 111.8 21.0 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KOS12482.1 - 4.1e-17 62.7 0.1 2.6e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS12482.1 - 2.2e-08 33.5 0.0 6.5e-07 28.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS12482.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS12482.1 - 0.00088 18.8 0.0 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS12482.1 - 0.0075 15.7 0.1 0.089 12.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 KOS12482.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PKD PF00801.15 KOS12482.1 - 0.084 12.6 0.6 36 4.2 0.1 3.4 3 1 0 3 3 3 0 PKD domain PXA PF02194.10 KOS12483.1 - 2.3e-16 59.8 0.0 1.2e-07 31.4 0.0 2.4 1 1 1 2 2 2 2 PXA domain Nexin_C PF08628.7 KOS12483.1 - 6.2e-06 26.2 0.1 0.00012 22.1 0.0 3.1 4 0 0 4 4 4 1 Sorting nexin C terminal Metallophos PF00149.23 KOS12484.1 - 4.6e-44 150.2 1.2 6e-44 149.8 0.9 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 KOS12484.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3649 PF12365.3 KOS12485.1 - 0.48 9.9 1.6 0.69 9.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Ribosomal_L23 PF00276.15 KOS12486.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Svf1 PF08622.5 KOS12487.1 - 0.034 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Svf1-like UDP-g_GGTase PF06427.6 KOS12488.1 - 2.4e-44 151.1 0.0 4e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KOS12488.1 - 8.1e-07 28.6 0.2 1.5e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 HMG_box PF00505.14 KOS12489.1 - 6.3e-19 68.0 10.9 6.4e-16 58.3 2.7 4.0 5 0 0 5 5 5 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS12489.1 - 1.9e-17 63.3 15.1 3.7e-15 56.0 2.2 2.8 3 0 0 3 3 3 2 HMG-box domain DUF1413 PF07205.6 KOS12489.1 - 0.01 15.3 1.4 0.014 14.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) Tol_Tol_Ttg2 PF05494.7 KOS12489.1 - 0.062 12.8 2.1 0.21 11.1 0.1 2.3 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 Elong_Iki1 PF10483.4 KOS12490.1 - 6.2e-13 48.7 0.1 3.2e-06 26.7 0.1 2.2 2 0 0 2 2 2 2 Elongator subunit Iki1 Csm1 PF12539.3 KOS12491.1 - 1.4e-07 31.9 0.1 3.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Spc7 PF08317.6 KOS12491.1 - 0.0042 15.7 9.4 0.0042 15.7 6.5 1.9 1 1 1 2 2 2 1 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 KOS12491.1 - 0.02 14.9 18.8 0.13 12.3 7.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF496 PF04363.7 KOS12491.1 - 0.27 11.0 4.3 0.78 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Phage_GP20 PF06810.6 KOS12491.1 - 0.68 9.3 14.4 0.14 11.5 6.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_13 PF13166.1 KOS12491.1 - 4.1 5.7 15.3 8.8 4.6 10.6 1.5 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KOS12491.1 - 5.8 6.0 11.6 8.7 5.4 8.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit KH_1 PF00013.24 KOS12492.1 - 8.9e-07 28.4 0.0 9.4e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 KH domain OB_NTP_bind PF07717.11 KOS12493.1 - 1.3e-20 73.3 0.1 2.9e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS12493.1 - 3.8e-20 71.8 0.3 6.9e-20 70.9 0.2 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS12493.1 - 3.1e-11 42.9 0.0 5.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS12493.1 - 1.1e-09 38.0 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS12493.1 - 7.2e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KOS12493.1 - 0.00046 19.8 0.1 0.0021 17.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 KOS12493.1 - 0.0024 17.5 0.0 0.005 16.4 0.0 1.5 1 0 0 1 1 1 1 Helicase T2SE PF00437.15 KOS12493.1 - 0.0031 16.4 0.0 0.0079 15.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KOS12493.1 - 0.0046 16.4 0.1 0.023 14.1 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KOS12493.1 - 0.018 14.1 0.2 0.073 12.1 0.1 2.1 1 1 0 1 1 1 0 Zeta toxin PhoH PF02562.11 KOS12493.1 - 0.038 13.2 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KOS12493.1 - 0.039 13.7 0.0 0.43 10.3 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KOS12493.1 - 0.095 12.4 3.1 0.079 12.7 0.3 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 KOS12493.1 - 0.17 11.7 0.0 3.3 7.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain PRP21_like_P PF12230.3 KOS12494.1 - 1.7e-49 168.4 3.3 1.7e-49 168.4 2.3 2.3 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KOS12494.1 - 5.8e-32 109.1 1.2 1.7e-17 62.8 0.1 2.4 2 0 0 2 2 2 2 Surp module Nipped-B_C PF12830.2 KOS12496.1 - 0.062 12.9 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF4106 PF13388.1 KOS12496.1 - 4.2 6.2 10.9 9.5 5.0 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CotH PF08757.6 KOS12496.1 - 8.8 5.4 7.1 5.6 6.1 2.6 1.9 2 0 0 2 2 2 0 CotH protein VCBS PF13517.1 KOS12497.1 - 5.4e-17 61.8 7.2 0.00023 21.4 0.0 4.9 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KOS12497.1 - 4.6e-14 51.6 0.1 0.042 13.5 0.0 5.5 5 0 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 KOS12497.1 - 0.00011 21.7 1.1 2.7 7.4 0.0 4.3 3 1 1 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region 2Fe-2S_thioredx PF01257.14 KOS12498.1 - 4.3e-61 204.7 0.2 5.4e-61 204.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 KOS12498.1 - 0.0091 16.2 0.3 0.037 14.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1636) LRR_8 PF13855.1 KOS12499.1 - 1.7e-09 37.2 2.6 0.0042 16.8 0.1 4.8 4 1 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 KOS12499.1 - 4e-09 35.6 7.9 0.23 11.6 0.1 9.1 12 0 0 12 12 12 2 Leucine Rich repeat LRR_4 PF12799.2 KOS12499.1 - 1.3e-05 24.6 5.5 1.3 8.7 0.0 5.4 7 0 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KOS12499.1 - 0.0015 18.4 7.7 64 4.4 0.0 8.0 8 1 0 8 8 8 0 Leucine rich repeat zf-HYPF PF07503.7 KOS12499.1 - 0.11 11.9 0.8 0.56 9.6 0.1 2.3 2 0 0 2 2 2 0 HypF finger tRNA_Me_trans PF03054.11 KOS12500.1 - 2.5e-103 345.3 0.0 2.8e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 KOS12500.1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 KOS12500.1 - 0.0037 16.1 0.0 0.68 8.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase AlaDh_PNT_N PF05222.10 KOS12501.1 - 2e-27 95.8 0.0 2.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KOS12501.1 - 1.5e-08 34.4 0.0 3.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lipase_3 PF01764.20 KOS12502.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KOS12502.1 - 0.0013 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KOS12502.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) V_ATPase_I PF01496.14 KOS12503.1 - 1.1e-280 932.8 0.1 1.3e-280 932.6 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BioW PF03744.8 KOS12503.1 - 0.016 14.6 0.7 0.028 13.8 0.5 1.3 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase DUF2353 PF09789.4 KOS12503.1 - 0.073 12.3 3.8 0.12 11.5 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Methyltransf_29 PF03141.11 KOS12503.1 - 0.31 9.3 1.5 2.5 6.3 0.1 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MtrG PF04210.8 KOS12503.1 - 0.53 9.9 2.4 7.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Polysacc_deac_1 PF01522.16 KOS12504.1 - 2.6e-29 101.3 0.0 4.4e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF566 PF04484.7 KOS12504.1 - 1.3 8.4 7.8 1.8 8.0 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Menin PF05053.8 KOS12504.1 - 3.9 5.5 6.8 5.8 4.9 4.7 1.2 1 0 0 1 1 1 0 Menin Pex2_Pex12 PF04757.9 KOS12505.1 - 1.6e-51 174.9 4.6 2.2e-51 174.4 3.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 KOS12505.1 - 0.0076 15.8 6.3 0.012 15.3 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS12505.1 - 0.03 14.3 7.4 0.048 13.6 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2142 PF09913.4 KOS12505.1 - 0.049 12.2 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) zf-C3HC4_4 PF15227.1 KOS12505.1 - 1.5 8.8 8.3 2.6 8.0 5.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS12505.1 - 6 6.7 8.7 13 5.6 6.1 1.6 1 1 0 1 1 1 0 Ring finger domain Thiolase_N PF00108.18 KOS12506.1 - 2.2e-91 305.4 4.3 3.1e-91 304.9 3.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS12506.1 - 3.5e-39 133.0 0.8 3.5e-39 133.0 0.6 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KOS12506.1 - 8.4e-06 25.4 9.7 2.1e-05 24.1 0.1 3.4 3 1 1 4 4 4 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KOS12506.1 - 0.025 14.2 4.0 0.21 11.2 0.0 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADK PF00406.17 KOS12507.1 - 5.6e-59 198.3 0.1 7e-59 198.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KOS12507.1 - 2.9e-13 49.2 0.0 5.8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KOS12507.1 - 9.7e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS12507.1 - 0.00013 21.1 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KOS12507.1 - 0.0041 17.9 0.0 0.011 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS12507.1 - 0.036 13.7 0.1 0.098 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KOS12507.1 - 0.036 14.2 0.1 0.082 13.1 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KOS12507.1 - 0.045 14.0 0.1 0.14 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 KOS12507.1 - 0.065 12.5 0.1 9.5 5.5 0.0 3.0 2 1 1 3 3 3 0 Thymidylate kinase Guanylate_kin PF00625.16 KOS12507.1 - 0.11 11.8 0.4 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase WD40 PF00400.27 KOS12508.1 - 3.8e-26 89.9 7.6 2.4e-06 27.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Synaptobrevin PF00957.16 KOS12509.1 - 2e-22 78.5 0.0 2.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KOS12509.1 - 1.2e-17 63.1 0.0 2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain T4SS PF07996.6 KOS12509.1 - 0.066 13.0 0.1 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins Hist_deacetyl PF00850.14 KOS12510.1 - 7.2e-78 262.0 0.0 9.4e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain S10_plectin PF03501.10 KOS12511.1 - 2.1e-40 136.5 0.1 2.5e-40 136.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HTH_45 PF14947.1 KOS12511.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix TrmB PF01978.14 KOS12511.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ADK PF00406.17 KOS12512.1 - 7.9e-43 145.9 0.0 9.6e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KOS12512.1 - 4.2e-12 45.5 0.0 9.3e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KOS12512.1 - 3.2e-08 34.4 0.0 6.5e-08 33.4 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS12512.1 - 1.1e-07 31.8 0.0 4.4e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS12512.1 - 5.1e-07 30.0 0.0 9.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS12512.1 - 0.0006 18.9 0.0 0.0021 17.2 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KOS12512.1 - 0.025 13.7 0.1 0.041 13.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KOS12512.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KOS12512.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KOS12512.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Complex1_LYR PF05347.10 KOS12513.1 - 1e-08 34.8 0.6 2.4e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS12513.1 - 4.3e-08 33.2 1.3 4.3e-08 33.2 0.9 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Snf7 PF03357.16 KOS12514.1 - 2.8e-19 69.1 19.7 4.3e-19 68.5 13.6 1.2 1 0 0 1 1 1 1 Snf7 PKI PF02827.11 KOS12514.1 - 0.06 13.4 2.2 0.13 12.4 1.5 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Toxin_52 PF15605.1 KOS12514.1 - 0.2 11.5 2.4 3.7 7.4 0.4 2.5 2 0 0 2 2 2 0 Putative toxin 52 DUF651 PF04895.7 KOS12514.1 - 0.4 10.3 6.3 5.4 6.6 0.0 3.2 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) AAA_13 PF13166.1 KOS12514.1 - 0.72 8.2 7.9 1.1 7.6 5.5 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KOS12514.1 - 0.76 7.5 2.7 1.7 6.3 1.7 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 KOS12514.1 - 1.4 9.3 20.4 0.036 14.3 2.7 3.5 3 1 1 4 4 4 0 Snapin/Pallidin TPR_11 PF13414.1 KOS12515.1 - 1.8e-21 75.5 26.3 9.1e-06 25.2 4.0 8.0 7 1 1 8 8 8 5 TPR repeat TPR_2 PF07719.12 KOS12515.1 - 6.4e-21 72.5 23.9 0.00067 19.3 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 KOS12515.1 - 3.4e-15 54.9 10.2 0.0065 16.0 0.0 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS12515.1 - 5e-14 51.5 41.2 0.00021 21.6 0.0 10.3 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS12515.1 - 1.8e-09 36.6 0.2 0.29 11.0 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS12515.1 - 3.8e-09 36.5 17.3 0.012 15.7 0.0 6.9 7 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KOS12515.1 - 5.6e-09 36.4 55.8 0.0018 18.8 0.1 9.7 6 2 5 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 KOS12515.1 - 1.5e-08 34.4 27.8 3.4e-05 23.7 0.8 6.8 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KOS12515.1 - 2.8e-08 32.9 17.3 0.24 11.2 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS12515.1 - 3.9e-08 33.5 24.4 0.088 13.1 0.0 8.0 6 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS12515.1 - 0.00043 20.2 14.2 13 6.2 0.0 8.8 10 1 0 10 10 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS12515.1 - 0.005 17.1 36.6 1.4 9.5 2.5 8.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS12515.1 - 0.0055 17.0 28.8 0.039 14.4 0.0 7.3 10 0 0 10 10 7 2 Tetratricopeptide repeat NAD_binding_1 PF00175.16 KOS12516.1 - 5.1e-31 107.4 0.0 8.1e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KOS12516.1 - 3.7e-25 87.9 0.0 5.4e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KOS12516.1 - 1.8e-06 27.9 0.0 7.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KOS12516.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ApbA PF02558.11 KOS12517.1 - 1.7e-31 108.6 0.0 2.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KOS12517.1 - 1.3e-24 86.5 0.0 2.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.1 KOS12517.1 - 0.00029 21.0 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 KOS12517.1 - 0.003 16.5 0.9 0.0052 15.7 0.2 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS12517.1 - 0.013 15.8 0.1 0.026 14.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KOS12517.1 - 0.021 14.6 0.3 0.044 13.6 0.1 1.6 2 0 0 2 2 2 0 ThiF family Pyr_redox_2 PF07992.9 KOS12517.1 - 0.033 14.0 0.7 0.19 11.5 0.1 2.1 1 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.22 KOS12518.1 - 7.5e-14 50.6 17.0 1.2e-08 34.2 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KOS12518.1 - 4.1e-12 46.2 10.0 6.4e-12 45.6 7.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KOS12518.1 - 2.1e-10 41.1 18.1 3.8e-07 30.7 6.9 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KOS12518.1 - 6.4e-10 38.6 11.1 1.5e-09 37.5 7.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KOS12518.1 - 1.1e-09 37.9 4.5 0.00029 20.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KOS12518.1 - 1.8e-09 37.4 20.7 8.5e-07 28.9 7.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KOS12518.1 - 2.7e-09 37.1 10.0 4.9e-09 36.3 7.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 KOS12518.1 - 6.5e-08 32.0 15.0 0.00028 20.6 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KOS12518.1 - 8.8e-07 28.5 17.7 0.00076 19.2 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KOS12518.1 - 1.2e-06 28.3 10.1 0.00039 20.5 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KOS12518.1 - 1.4e-05 25.3 10.7 0.00028 21.1 8.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KOS12518.1 - 2.4e-05 24.6 9.9 0.016 15.6 0.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KOS12518.1 - 3.8e-05 24.1 7.6 0.023 15.2 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KOS12518.1 - 0.00073 19.8 15.0 0.13 12.7 2.7 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 KOS12518.1 - 0.012 16.0 18.4 0.015 15.8 4.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KOS12518.1 - 0.39 10.8 4.4 5.7 7.1 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Brix PF04427.13 KOS12519.1 - 8.6e-25 87.5 0.0 1.2e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF455 PF04305.9 KOS12520.1 - 1.4e-92 309.5 0.0 1.8e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KOS12520.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Mog1 PF04603.7 KOS12521.1 - 1.3e-27 96.4 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CAP_N PF01213.14 KOS12522.1 - 6.3e-83 278.6 17.0 1.6e-82 277.2 11.8 1.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KOS12522.1 - 8.5e-53 177.9 0.0 1.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KOS12522.1 - 0.0021 17.4 1.6 0.0036 16.6 1.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C UCH PF00443.24 KOS12523.1 - 2.5e-45 154.6 0.0 4.9e-45 153.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS12523.1 - 7.4e-20 71.5 0.0 2.6e-19 69.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KOS12523.1 - 1.9e-19 69.5 26.7 2.5e-18 65.9 3.1 3.8 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KOS12523.1 - 1.1e-18 66.5 1.1 3.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 KOS12523.1 - 0.0015 17.9 0.6 0.6 9.6 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain HLH PF00010.21 KOS12524.1 - 4.1e-08 32.8 0.6 8e-08 31.8 0.4 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 KOS12524.1 - 0.05 13.5 1.2 0.12 12.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Zip PF02535.17 KOS12524.1 - 0.51 9.2 11.7 0.28 10.1 1.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Apt1 PF10351.4 KOS12526.1 - 2.1e-79 267.5 0.7 2.1e-79 267.5 0.5 1.7 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 KOS12526.1 - 3.6e-35 121.2 0.0 7e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_WPPW PF10359.4 KOS12526.1 - 2.3e-34 118.6 2.7 4.7e-34 117.6 1.9 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KOS12526.1 - 3.7e-25 88.4 0.0 1.3e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KOS12526.1 - 8.4e-09 35.7 0.1 4.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain LAP1C PF05609.7 KOS12527.1 - 0.31 9.6 3.0 0.32 9.6 1.3 1.5 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SCA7 PF08313.7 KOS12528.1 - 7e-29 99.2 0.1 1.9e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF2011 PF09428.5 KOS12528.1 - 0.018 14.9 0.6 0.043 13.7 0.4 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) zf-UDP PF14569.1 KOS12528.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger tRNA-synt_2 PF00152.15 KOS12529.1 - 9.8e-78 261.2 0.1 1.5e-77 260.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KOS12529.1 - 4.5e-15 55.2 0.0 7.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 KOS12529.1 - 0.00059 19.0 0.1 0.05 12.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MIF4G PF02854.14 KOS12530.1 - 3.4e-30 105.0 0.3 3e-29 101.9 0.0 2.5 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 KOS12530.1 - 2.6e-26 91.5 0.1 5.4e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 MA3 domain MRP-S33 PF08293.6 KOS12530.1 - 0.042 13.8 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Thg1C PF14413.1 KOS12531.1 - 1.4e-42 144.1 0.0 2e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KOS12531.1 - 8.2e-28 96.7 0.1 7.3e-26 90.3 0.1 2.2 1 1 0 1 1 1 1 tRNAHis guanylyltransferase RNase_H2-Ydr279 PF09468.5 KOS12532.1 - 4e-25 88.6 0.0 5.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF1691 PF07950.6 KOS12533.1 - 4.5e-15 55.5 9.3 2.7e-12 46.5 0.2 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) Abhydrolase_3 PF07859.8 KOS12535.1 - 1.1e-38 132.9 0.0 4.9e-30 104.6 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS12535.1 - 2.8e-06 26.2 0.0 7.9e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS12535.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4187 PF13821.1 KOS12536.1 - 1.6e-16 59.5 2.9 2.8e-16 58.8 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) PV-1 PF06637.6 KOS12536.1 - 0.031 12.8 2.9 0.047 12.2 2.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1776 PF08643.5 KOS12537.1 - 0.0014 17.8 0.0 0.008 15.3 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KOS12537.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase SYF2 PF08231.7 KOS12538.1 - 4.9e-40 137.1 15.9 4.9e-40 137.1 11.0 2.0 2 1 0 2 2 2 1 SYF2 splicing factor Methyltransf_16 PF10294.4 KOS12539.1 - 2.9e-17 62.6 0.0 4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS12539.1 - 2.6e-06 27.9 0.2 4.5e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS12539.1 - 4e-05 23.3 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12539.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS12539.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12539.1 - 0.012 15.6 1.9 0.02 14.9 0.7 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KOS12539.1 - 0.035 13.5 0.1 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KOS12539.1 - 0.036 13.1 0.1 0.049 12.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KOS12539.1 - 0.054 13.0 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KOS12539.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NNMT_PNMT_TEMT PF01234.12 KOS12539.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-CCCH PF00642.19 KOS12540.1 - 0.00015 21.3 2.1 0.00015 21.3 1.5 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KOS12540.1 - 0.0002 21.1 0.1 0.00038 20.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS12540.1 - 0.0063 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 KOS12540.1 - 0.017 14.9 0.4 0.017 14.9 0.3 1.8 2 0 0 2 2 2 0 FYVE zinc finger RRM_1 PF00076.17 KOS12540.1 - 0.051 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 KOS12540.1 - 0.054 13.5 2.1 0.18 11.8 1.4 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ECR1_N PF14382.1 KOS12541.1 - 9.1e-10 37.6 0.1 1.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KOS12541.1 - 8.3e-06 25.6 0.1 7.8e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 KOS12541.1 - 0.025 14.6 0.1 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 S1 RNA binding domain UQ_con PF00179.21 KOS12543.1 - 1.9e-14 53.3 0.0 2e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS12543.1 - 0.0068 16.1 0.0 0.01 15.5 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B Nuc_sug_transp PF04142.10 KOS12544.1 - 9.9e-12 44.4 5.6 1.6e-11 43.7 3.9 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KOS12544.1 - 0.0013 18.7 1.0 0.0013 18.7 0.7 3.2 2 1 1 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 KOS12544.1 - 0.035 12.9 8.2 0.36 9.6 5.7 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 KOS12544.1 - 0.16 10.8 16.7 0.27 10.1 11.6 1.3 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 KOS12544.1 - 5.4 6.6 19.6 0.75 9.4 1.1 3.1 3 1 0 3 3 3 0 Triose-phosphate Transporter family Asn_synthase PF00733.16 KOS12545.1 - 2.2e-66 223.9 0.1 4.4e-66 222.9 0.1 1.5 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KOS12545.1 - 4.8e-38 129.7 0.0 8.7e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KOS12545.1 - 2.2e-30 105.3 0.0 6e-30 103.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KOS12545.1 - 3.9e-07 29.5 0.0 7.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KOS12545.1 - 0.00021 20.1 0.0 0.038 12.6 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KOS12545.1 - 0.002 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 KOS12545.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DnaJ PF00226.26 KOS12546.1 - 4.6e-23 80.7 0.8 7.6e-23 80.0 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS12546.1 - 3.8e-20 71.5 0.0 3.9e-17 61.9 0.0 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KOS12546.1 - 5.5e-16 58.3 13.9 8.5e-16 57.7 9.6 1.3 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 KOS12546.1 - 0.39 10.2 0.1 0.39 10.2 0.0 2.9 4 0 0 4 4 4 0 A2L zinc ribbon domain DZR PF12773.2 KOS12546.1 - 0.54 10.1 11.0 2.8 7.8 1.8 2.1 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 KOS12546.1 - 1.2 8.7 6.6 10 5.8 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KOS12546.1 - 1.3 9.0 11.5 2.1 8.3 0.1 3.9 3 1 1 4 4 4 0 zinc-finger zf-Di19 PF05605.7 KOS12546.1 - 3 8.0 9.8 5.9 7.0 0.3 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S30 PF04758.9 KOS12547.1 - 1.4e-30 104.7 7.5 1.6e-30 104.6 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ras PF00071.17 KOS12548.1 - 1e-52 177.7 0.0 1.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS12548.1 - 2.9e-15 56.7 0.0 4.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS12548.1 - 6.5e-06 25.4 0.0 9.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA PF00004.24 KOS12549.1 - 1.5e-40 138.4 0.0 3.3e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS12549.1 - 9.8e-06 25.7 0.0 0.001 19.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS12549.1 - 3.1e-05 23.7 0.1 0.00018 21.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KOS12549.1 - 0.00024 20.0 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 KOS12549.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS12549.1 - 0.0011 19.0 0.0 0.0069 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS12549.1 - 0.0033 18.2 0.1 0.0082 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS12549.1 - 0.006 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KOS12549.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS12549.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS12549.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KOS12549.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS12549.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KOS12549.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KOS12549.1 - 0.028 14.0 0.0 3.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 KOS12549.1 - 0.039 13.5 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KOS12549.1 - 0.053 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KOS12549.1 - 0.054 12.2 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KOS12549.1 - 0.054 12.8 0.3 0.25 10.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KOS12549.1 - 0.058 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KOS12549.1 - 0.067 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KOS12549.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KOS12549.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HECT PF00632.20 KOS12550.1 - 1.9e-92 309.8 0.0 2.6e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KOS12550.1 - 9.9e-32 108.4 17.6 8.4e-11 41.5 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KOS12550.1 - 4.2e-16 58.5 0.3 9.6e-16 57.4 0.2 1.6 1 0 0 1 1 1 1 C2 domain RNA_polI_A34 PF08208.6 KOS12551.1 - 1.1e-13 51.3 8.4 3e-06 27.0 6.7 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.4 KOS12551.1 - 0.027 13.9 15.8 0.038 13.4 11.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-C_C PF11699.3 KOS12552.1 - 1.3e-28 98.7 0.3 2.1e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KOS12552.1 - 2.4e-05 23.7 0.0 5.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Mif2_N PF15624.1 KOS12552.1 - 0.00011 22.8 0.2 0.00011 22.8 0.2 2.8 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal AraC_binding PF02311.14 KOS12552.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain HgmA PF04209.8 KOS12552.1 - 0.096 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase IMS PF00817.15 KOS12554.1 - 8e-35 119.8 0.1 1.5e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KOS12554.1 - 4.9e-14 52.3 0.0 1.5e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 KOS12554.1 - 4.9e-05 23.3 0.0 9.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 KOS12554.1 - 0.00031 20.6 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.2 KOS12554.1 - 0.00047 19.9 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF4414 PF14377.1 KOS12554.1 - 0.062 13.2 7.2 0.07 13.0 2.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) DUF1805 PF08827.6 KOS12554.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) STAG PF08514.6 KOS12555.1 - 2.2e-21 75.7 0.3 7.1e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.2 KOS12555.1 - 9.5e-06 25.5 0.4 0.00027 20.8 0.1 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KOS12555.1 - 2.8e-05 23.7 0.9 0.26 11.4 0.0 5.4 4 0 0 4 4 4 1 HEAT repeat WLM PF08325.5 KOS12556.1 - 7e-47 159.7 0.0 9.3e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KOS12556.1 - 0.0011 18.8 0.5 0.0026 17.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 KOS12556.1 - 0.049 13.2 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 SprT-like family CLTH PF10607.4 KOS12557.1 - 3.8e-16 59.0 0.0 5.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KOS12557.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 LisH Response_reg PF00072.19 KOS12560.1 - 2e-21 76.0 0.1 3.4e-20 72.1 0.1 2.4 1 1 0 1 1 1 1 Response regulator receiver domain DUF1748 PF08520.5 KOS12561.1 - 1.8e-21 75.5 0.0 2.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2034 PF10356.4 KOS12562.1 - 4.1e-24 84.7 0.5 8.5e-21 73.9 0.3 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KOS12562.1 - 1.7e-07 31.0 0.0 5.9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Restriction endonuclease Ribonuc_red_sm PF00268.16 KOS12563.1 - 1.4e-116 388.4 2.2 1.7e-116 388.1 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GST_C_2 PF13410.1 KOS12565.1 - 0.0036 17.1 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS12565.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRAP_alpha PF03896.11 KOS12565.1 - 0.47 9.3 4.2 0.64 8.9 2.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 KOS12565.1 - 0.76 9.2 15.0 1.6 8.2 10.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin adh_short PF00106.20 KOS12567.1 - 1.3e-09 38.2 3.5 4.7e-05 23.3 1.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KOS12567.1 - 4.7e-06 26.4 0.3 0.00031 20.4 0.2 2.4 2 0 0 2 2 2 2 KR domain RINGv PF12906.2 KOS12568.1 - 1e-12 47.8 7.2 1.7e-12 47.1 5.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KOS12568.1 - 0.0078 16.0 5.8 0.017 14.9 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KOS12568.1 - 0.071 13.0 3.0 0.14 12.0 2.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 KOS12568.1 - 0.16 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 KOS12568.1 - 0.54 9.9 6.7 1.7 8.3 0.1 2.2 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.17 KOS12568.1 - 2 8.1 6.6 5.1 6.9 0.1 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Smg4_UPF3 PF03467.10 KOS12569.1 - 9.9e-22 77.7 0.7 2.1e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Smg-4/UPF3 family DUF684 PF05075.9 KOS12569.1 - 0.014 14.0 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) ATP-synt_ab PF00006.20 KOS12570.1 - 1.3e-107 358.1 0.0 1.8e-107 357.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS12570.1 - 1.3e-21 77.1 0.1 2.9e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS12570.1 - 1.7e-13 50.5 1.8 5e-13 49.0 1.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Spore_coat_CotO PF14153.1 KOS12571.1 - 0.23 10.9 9.8 0.3 10.4 6.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 KOS12571.1 - 0.63 9.3 10.9 1 8.6 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 KOS12571.1 - 0.72 9.8 13.3 1.3 8.9 9.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.5 KOS12571.1 - 1.2 8.2 31.4 1.6 7.8 21.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Effector_1 PF04518.7 KOS12571.1 - 2.2 7.1 8.8 2.9 6.7 6.1 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3435 PF11917.3 KOS12571.1 - 2.2 6.8 12.4 3.2 6.3 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DDRGK PF09756.4 KOS12571.1 - 2.7 7.3 17.0 3.7 6.9 11.8 1.2 1 0 0 1 1 1 0 DDRGK domain TATR PF03430.8 KOS12571.1 - 2.8 6.4 6.3 3.3 6.2 4.3 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator SAPS PF04499.10 KOS12571.1 - 5.2 5.5 6.3 6.7 5.2 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.7 KOS12571.1 - 5.4 5.5 13.6 5.9 5.4 9.4 1.0 1 0 0 1 1 1 0 Hamartin protein HSP70 PF00012.15 KOS12571.1 - 5.5 4.7 13.0 7 4.4 9.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Ycf1 PF05758.7 KOS12571.1 - 5.6 4.5 6.8 6.4 4.3 4.7 1.0 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 KOS12571.1 - 5.9 5.0 18.4 8.5 4.4 12.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.3 KOS12571.1 - 7 5.2 18.8 9.1 4.9 13.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DASH_Dad2 PF08654.5 KOS12572.1 - 2.9e-26 91.4 0.3 3.5e-26 91.1 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF1517 PF07466.6 KOS12572.1 - 0.086 11.8 3.0 0.1 11.5 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) NMT PF01233.14 KOS12573.1 - 3.7e-76 254.2 0.0 5.6e-76 253.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KOS12573.1 - 1.4e-65 220.2 0.0 2.1e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KOS12573.1 - 1.1e-06 28.5 0.1 8.6e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS12573.1 - 0.021 14.8 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS12573.1 - 0.027 14.6 0.1 0.07 13.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PTCB-BRCT PF12738.2 KOS12574.1 - 8.5e-36 121.6 0.3 1.8e-15 56.5 0.0 4.7 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 KOS12574.1 - 6.8e-23 80.6 0.0 1.8e-09 37.6 0.0 4.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain zf-Tim10_DDP PF02953.10 KOS12575.1 - 3.3e-23 80.7 0.3 3.9e-23 80.5 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TMA7 PF09072.5 KOS12576.1 - 8.2e-20 71.0 18.0 1.2e-19 70.4 12.5 1.3 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF2611 PF11022.3 KOS12576.1 - 0.0052 16.8 0.1 0.0074 16.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) GCV_H PF01597.14 KOS12577.1 - 1.3e-41 141.0 0.2 1.6e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KOS12577.1 - 0.00093 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KOS12577.1 - 0.041 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain FA_hydroxylase PF04116.8 KOS12578.1 - 6e-17 62.0 14.0 6e-17 62.0 9.7 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Shugoshin_C PF07557.6 KOS12579.1 - 6.7e-09 35.0 4.5 6.7e-09 35.0 3.1 5.1 5 0 0 5 5 5 1 Shugoshin C terminus Striatin PF08232.7 KOS12579.1 - 0.01 16.1 2.2 0.035 14.4 0.0 2.5 2 1 0 2 2 2 0 Striatin family Vac_Fusion PF02346.11 KOS12579.1 - 0.095 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Shugoshin_N PF07558.6 KOS12579.1 - 0.095 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Atx10homo_assoc PF09759.4 KOS12581.1 - 3.8e-17 61.8 0.0 2.4e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 KOS12581.1 - 0.0029 17.8 0.2 29 5.0 0.0 4.0 3 2 0 3 3 3 2 HEAT repeats WD40 PF00400.27 KOS12582.1 - 1.3e-13 50.2 11.3 0.0011 18.7 0.2 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Hira PF07569.6 KOS12582.1 - 0.034 13.3 0.0 0.087 12.0 0.0 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split NCA2 PF08637.5 KOS12583.1 - 1.2e-51 175.3 0.0 1.7e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 UDPGT PF00201.13 KOS12584.1 - 3.7e-05 22.4 0.0 5.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase YL1 PF05764.8 KOS12585.1 - 6.1e-44 150.4 17.6 6.1e-44 150.4 12.2 1.8 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 KOS12585.1 - 1.1e-13 50.4 0.5 2e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Asp PF00026.18 KOS12586.1 - 2.9e-65 220.5 0.6 3.6e-65 220.2 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS12586.1 - 2.3e-08 34.1 0.8 1.6e-07 31.4 0.4 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal P_proprotein PF01483.15 KOS12586.1 - 0.088 12.5 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Proprotein convertase P-domain Mitofilin PF09731.4 KOS12587.1 - 4.1e-107 359.2 21.5 4.7e-107 359.0 14.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 KOS12587.1 - 0.001 18.5 7.0 0.001 18.5 4.8 3.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Med9 PF07544.8 KOS12587.1 - 0.0098 15.6 1.6 0.0098 15.6 1.1 3.4 4 2 0 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 UPF0449 PF15136.1 KOS12587.1 - 0.021 15.0 1.3 0.021 15.0 0.9 3.5 5 1 1 6 6 6 0 Uncharacterised protein family UPF0449 DUF4085 PF13315.1 KOS12587.1 - 7.4 5.8 12.5 0.87 8.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Ndc80_HEC PF03801.8 KOS12588.1 - 2.4e-32 111.5 0.0 5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family WXG100 PF06013.7 KOS12588.1 - 0.0026 17.7 1.3 0.0026 17.7 0.9 4.2 3 2 1 4 4 4 1 Proteins of 100 residues with WXG ArsC PF03960.10 KOS12588.1 - 0.066 13.2 0.7 0.2 11.7 0.5 1.8 1 0 0 1 1 1 0 ArsC family HALZ PF02183.13 KOS12588.1 - 3.3 7.4 10.6 4.3 7.1 0.0 4.1 4 1 1 5 5 5 0 Homeobox associated leucine zipper ParA PF10609.4 KOS12589.1 - 8.8e-30 102.4 0.0 1.3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KOS12589.1 - 8.7e-11 41.5 0.0 4.1e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KOS12589.1 - 3.7e-05 23.7 0.0 0.00019 21.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS12589.1 - 6.9e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KOS12589.1 - 8.1e-05 21.8 1.1 0.00039 19.5 0.1 2.2 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_19 PF13245.1 KOS12589.1 - 0.0033 17.1 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Part of AAA domain MipZ PF09140.6 KOS12589.1 - 0.021 13.9 0.0 0.1 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ DUF258 PF03193.11 KOS12589.1 - 0.044 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS12589.1 - 0.054 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS12589.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cache_3 PF14827.1 KOS12589.1 - 0.13 12.1 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase Pam16 PF03656.8 KOS12590.1 - 2.3e-19 69.4 0.8 7.9e-19 67.7 0.5 1.7 1 1 0 1 1 1 1 Pam16 Chorismate_bind PF00425.13 KOS12591.1 - 1.2e-89 300.0 0.0 1.7e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KOS12591.1 - 2.9e-27 95.3 0.0 3.2e-26 91.9 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region tRNA-synt_1g PF09334.6 KOS12592.1 - 1.3e-103 346.6 0.0 3.5e-103 345.2 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KOS12592.1 - 7.4e-15 53.9 0.4 2.8e-09 35.5 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KOS12592.1 - 8.1e-08 31.7 0.0 0.0029 16.7 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KOS12592.1 - 0.068 11.8 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) UQ_con PF00179.21 KOS12593.1 - 5.5e-41 139.2 0.0 6.7e-41 138.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS12593.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS12593.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 RWD domain DHBP_synthase PF00926.14 KOS12594.1 - 1.7e-74 249.2 0.0 1.9e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase tRNA-synt_1 PF00133.17 KOS12595.1 - 2.6e-210 699.4 0.0 1.1e-209 697.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS12595.1 - 2.4e-35 121.5 0.1 4.4e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KOS12595.1 - 2e-16 59.6 0.1 1.2e-07 30.8 0.0 4.4 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KOS12595.1 - 3.9e-13 49.1 0.4 1e-07 31.4 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KOS12595.1 - 0.0023 17.0 0.0 0.77 8.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KOS12595.1 - 0.0036 16.1 0.0 0.053 12.3 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) Pkinase PF00069.20 KOS12596.1 - 5.4e-42 143.7 0.0 3.5e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12596.1 - 1.1e-13 50.8 0.0 2.3e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Tubulin PF00091.20 KOS12596.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain EMP24_GP25L PF01105.19 KOS12596.1 - 0.018 14.7 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APH PF01636.18 KOS12596.1 - 0.037 13.7 0.9 0.24 11.1 0.0 2.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS12596.1 - 0.13 11.2 0.0 6.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CDP-OH_P_transf PF01066.16 KOS12597.1 - 5.8e-16 58.6 2.8 5.8e-16 58.6 1.9 3.1 2 2 1 3 3 3 1 CDP-alcohol phosphatidyltransferase Dynamin_N PF00350.18 KOS12598.1 - 1.5e-40 138.7 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KOS12598.1 - 4.2e-08 32.3 0.0 2.8e-07 29.6 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region Miro PF08477.8 KOS12598.1 - 0.0073 16.8 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS12598.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RE_AlwI PF09491.5 KOS12598.1 - 0.15 10.4 0.1 12 4.2 0.0 2.1 2 0 0 2 2 2 0 AlwI restriction endonuclease adh_short PF00106.20 KOS12599.1 - 1.1e-20 74.1 0.2 1.6e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS12599.1 - 6.8e-09 35.8 0.2 9.3e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS12599.1 - 1.5e-07 31.2 0.1 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 KR domain FKBP_C PF00254.23 KOS12600.1 - 2.2e-31 107.7 0.0 4.9e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CENP-T PF15511.1 KOS12600.1 - 0.063 12.5 50.6 0.13 11.4 18.0 2.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cyclin_N PF00134.18 KOS12601.1 - 4.3e-44 149.1 0.1 1.9e-41 140.5 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS12601.1 - 3.7e-31 107.5 0.1 6.4e-31 106.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Vps51 PF08700.6 KOS12602.1 - 1.9e-12 46.8 0.0 3.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 MAGE PF01454.14 KOS12603.1 - 2.2e-15 56.5 0.0 3.6e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 MAGE family HSF_DNA-bind PF00447.12 KOS12603.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 HSF-type DNA-binding Spindle_Spc25 PF08234.7 KOS12604.1 - 1.7e-12 47.1 0.0 3.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Cortex-I_coil PF09304.5 KOS12604.1 - 1.1e-08 35.1 17.7 1.9e-08 34.2 12.3 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil ERM PF00769.14 KOS12604.1 - 0.00037 20.0 12.9 0.00042 19.9 8.9 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.6 KOS12604.1 - 0.0017 17.1 9.8 0.0024 16.5 6.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Bacillus_HBL PF05791.6 KOS12604.1 - 0.0084 15.5 2.8 0.015 14.7 2.0 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 KOS12604.1 - 0.01 15.7 6.7 0.01 15.7 4.7 2.7 2 1 1 3 3 1 0 FlxA-like protein bZIP_1 PF00170.16 KOS12604.1 - 0.02 14.8 0.6 0.02 14.8 0.4 3.3 2 1 1 3 3 3 0 bZIP transcription factor Gmx_para_CXXCG PF09535.5 KOS12604.1 - 0.027 13.4 0.0 0.053 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Exonuc_VII_L PF02601.10 KOS12604.1 - 0.032 13.4 8.2 0.041 13.0 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1192 PF06698.6 KOS12604.1 - 0.082 12.7 0.5 0.082 12.7 0.4 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1192) Reo_sigmaC PF04582.7 KOS12604.1 - 0.12 11.5 0.8 0.33 10.0 0.1 1.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Protein_K PF12283.3 KOS12604.1 - 0.12 12.2 0.2 0.97 9.3 0.0 2.5 3 0 0 3 3 2 0 Bacteriophage protein K CENP-F_leu_zip PF10473.4 KOS12604.1 - 0.15 11.9 19.7 0.23 11.2 13.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KOS12604.1 - 0.18 10.8 15.6 0.3 10.1 10.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 KOS12604.1 - 0.23 11.7 17.6 0.47 10.7 12.2 1.4 1 0 0 1 1 1 0 Striatin family DUF342 PF03961.8 KOS12604.1 - 0.28 9.5 7.5 0.42 8.9 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KOS12604.1 - 0.34 8.6 9.2 0.45 8.3 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 KOS12604.1 - 0.38 10.8 17.1 0.12 12.5 4.8 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4559 PF15112.1 KOS12604.1 - 0.41 9.7 10.0 0.78 8.8 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Cluap1 PF10234.4 KOS12604.1 - 0.52 9.4 18.3 1.7 7.7 2.5 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Vfa1 PF08432.5 KOS12604.1 - 0.58 10.1 13.0 0.85 9.6 9.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Lectin_N PF03954.9 KOS12604.1 - 0.63 9.4 4.5 0.77 9.1 2.1 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain AAA_13 PF13166.1 KOS12604.1 - 0.68 8.3 9.8 1.1 7.6 6.8 1.3 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 KOS12604.1 - 0.83 8.8 19.3 0.092 11.9 6.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 KOS12604.1 - 1.2 8.7 22.1 0.25 10.9 5.4 2.3 1 1 1 2 2 2 0 Mnd1 family DUF2400 PF09674.5 KOS12604.1 - 1.4 8.5 5.7 1.6 8.3 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) HlyD PF00529.15 KOS12604.1 - 2.5 7.3 16.0 3.8 6.7 11.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Filament PF00038.16 KOS12604.1 - 2.6 7.4 21.6 6.9 6.0 15.0 1.6 1 1 0 1 1 1 0 Intermediate filament protein Prominin PF05478.6 KOS12604.1 - 3.3 5.1 7.5 5.2 4.4 4.9 1.4 1 1 0 1 1 1 0 Prominin HAUS6_N PF14661.1 KOS12604.1 - 3.6 6.8 18.8 7.6 5.8 12.7 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Seryl_tRNA_N PF02403.17 KOS12604.1 - 4.9 7.2 18.3 0.049 13.6 4.2 2.4 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 KOS12604.1 - 5.4 6.8 9.0 0.97 9.2 1.4 3.1 2 1 1 3 3 2 0 Homeobox associated leucine zipper Macoilin PF09726.4 KOS12604.1 - 7.4 4.7 18.0 9.9 4.2 12.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TMF_TATA_bd PF12325.3 KOS12604.1 - 9 6.0 21.2 1.4 8.6 11.3 2.2 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding Yippee-Mis18 PF03226.9 KOS12605.1 - 6.7e-23 80.5 0.1 9.6e-23 80.0 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.2 KOS12605.1 - 0.0058 16.4 0.2 1.7 8.4 0.1 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain ASD2 PF08687.6 KOS12605.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 RIG-I_C-RD PF11648.3 KOS12605.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I MAPEG PF01124.13 KOS12606.1 - 3.2e-23 81.7 6.4 3.7e-23 81.5 4.4 1.0 1 0 0 1 1 1 1 MAPEG family DUF448 PF04296.8 KOS12607.1 - 7.4e-05 22.2 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF448) Ribosomal_S3_C PF00189.15 KOS12608.1 - 2.2e-16 59.8 0.1 3.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KOS12608.1 - 2e-10 40.0 0.0 4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 KH domain HECT PF00632.20 KOS12610.1 - 1.7e-99 332.9 0.0 2.3e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ABC1 PF03109.11 KOS12611.1 - 2.6e-28 98.3 0.1 5.3e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KOS12611.1 - 0.035 13.4 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family WaaY PF06176.6 KOS12611.1 - 0.042 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-C2H2 PF00096.21 KOS12612.1 - 6.3e-06 26.2 1.5 0.084 13.2 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KOS12612.1 - 3.8e-05 23.7 3.2 0.031 14.4 0.4 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KOS12612.1 - 0.00013 22.0 2.8 0.016 15.5 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KOS12612.1 - 0.00028 20.9 1.6 0.18 11.9 0.2 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KOS12612.1 - 0.091 12.7 1.8 0.17 11.8 0.0 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS12612.1 - 0.61 10.4 6.5 0.78 10.1 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain ETS_PEA3_N PF04621.8 KOS12612.1 - 1.3 8.1 8.9 0.83 8.8 5.2 1.4 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Pkinase PF00069.20 KOS12613.1 - 5.4e-55 186.3 0.0 1.5e-54 184.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12613.1 - 1e-24 87.0 0.0 4.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L32e PF01655.13 KOS12614.1 - 1e-48 163.9 3.4 1.2e-48 163.6 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 LSM PF01423.17 KOS12615.1 - 9.3e-18 63.5 1.6 1.6e-17 62.7 1.1 1.4 1 1 0 1 1 1 1 LSM domain Pox_Ag35 PF03286.9 KOS12615.1 - 0.015 14.8 1.2 0.017 14.6 0.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 KOS12615.1 - 0.027 14.7 3.1 0.043 14.1 2.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-protein PF00469.15 KOS12615.1 - 0.13 11.6 0.6 0.16 11.3 0.4 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef APC_CDC26 PF10471.4 KOS12615.1 - 0.28 11.9 1.6 0.45 11.2 1.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Abhydro_lipase PF04083.11 KOS12616.1 - 4.1e-16 58.1 0.1 1.6e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KOS12616.1 - 9.1e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS12616.1 - 0.0034 17.1 0.7 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Zip PF02535.17 KOS12616.1 - 3.2 6.6 6.3 6.5 5.6 4.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PP2C PF00481.16 KOS12617.1 - 9.2e-29 100.5 0.0 1.4e-18 67.1 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 KOS12617.1 - 0.00064 19.1 0.0 0.012 14.9 0.0 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C Carn_acyltransf PF00755.15 KOS12618.1 - 1.4e-128 429.5 0.0 3.3e-128 428.3 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase MKT1_C PF12246.3 KOS12619.1 - 6.6e-62 208.6 0.1 1.1e-61 207.8 0.1 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KOS12619.1 - 7.1e-21 74.3 0.0 1.6e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KOS12619.1 - 8.4e-08 32.4 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS12619.1 - 2.4e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region CRAL_TRIO PF00650.15 KOS12620.1 - 5.4e-21 74.7 0.0 9.2e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Stimulus_sens_1 PF13756.1 KOS12620.1 - 0.19 12.1 1.8 0.22 11.9 0.2 1.9 2 0 0 2 2 2 0 Stimulus-sensing domain SPA PF08616.5 KOS12621.1 - 9.7e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KOS12621.1 - 1.2e-05 23.9 0.0 2.2e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 KOS12621.1 - 0.016 14.9 0.0 0.066 12.9 0.0 2.0 1 1 0 1 1 1 0 DENN (AEX-3) domain Sec20 PF03908.8 KOS12623.1 - 2.8e-16 58.9 1.8 4.3e-16 58.3 0.3 2.0 2 0 0 2 2 2 1 Sec20 Syntaxin_2 PF14523.1 KOS12623.1 - 0.05 13.6 1.7 0.097 12.7 0.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF2317 PF10079.4 KOS12623.1 - 0.8 8.2 6.1 5.2 5.5 2.4 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Mnd1 PF03962.10 KOS12623.1 - 6.8 6.3 6.3 0.92 9.1 1.4 1.6 2 0 0 2 2 2 0 Mnd1 family DUF500 PF04366.7 KOS12624.1 - 5.8e-30 103.3 0.0 9.1e-30 102.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) MFS_1 PF07690.11 KOS12625.1 - 3.1e-40 137.9 32.1 3.1e-40 137.9 22.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS12625.1 - 4.7e-14 51.8 27.5 4e-13 48.7 19.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 KOS12625.1 - 3.4e-05 22.5 9.5 3.4e-05 22.5 6.6 2.4 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like HLH PF00010.21 KOS12626.1 - 8.8e-13 47.7 3.4 8.8e-13 47.7 2.4 2.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain IU_nuc_hydro PF01156.14 KOS12627.1 - 2.7e-57 194.3 0.0 3.5e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase His_Phos_1 PF00300.17 KOS12628.1 - 5.5e-15 55.7 0.0 2.2e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3752 PF12572.3 KOS12629.1 - 1e-08 35.4 15.8 1e-08 35.4 10.9 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3752) TIP39 PF14980.1 KOS12629.1 - 0.051 13.2 1.4 0.14 11.7 1.0 1.8 1 0 0 1 1 1 0 TIP39 peptide eIF-3_zeta PF05091.7 KOS12631.1 - 6.2e-175 582.7 0.0 7.5e-175 582.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Aminotran_1_2 PF00155.16 KOS12632.1 - 7.4e-21 74.5 0.0 8.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KOS12632.1 - 0.0067 15.0 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase JAB PF01398.16 KOS12633.1 - 5.1e-28 97.1 0.1 8.8e-28 96.3 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KOS12633.1 - 2.2e-06 27.1 0.0 5.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RFC1 PF08519.7 KOS12634.1 - 1.2e-48 164.7 0.0 2.5e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KOS12634.1 - 1.5e-11 44.2 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KOS12634.1 - 9.1e-08 32.3 0.0 2.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KOS12634.1 - 3.1e-06 26.1 0.1 8.5e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS12634.1 - 0.00033 20.7 0.0 0.0008 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS12634.1 - 0.00097 19.1 0.0 0.012 15.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KOS12634.1 - 0.00098 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KOS12634.1 - 0.007 17.1 0.0 0.026 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KOS12634.1 - 0.01 15.4 0.1 0.023 14.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KOS12634.1 - 0.011 15.4 0.0 0.061 12.9 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KOS12634.1 - 0.012 15.4 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 KOS12634.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 KOS12634.1 - 0.044 13.6 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 KOS12634.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain Kdo PF06293.9 KOS12635.1 - 3.4e-09 36.0 0.0 9.4e-09 34.6 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS12635.1 - 6.1e-09 35.9 1.8 1.5e-05 24.9 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KOS12635.1 - 1.2e-08 34.4 0.0 1.7e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KOS12635.1 - 1.7e-05 24.2 0.0 6.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 KOS12635.1 - 0.00013 21.1 0.0 0.00017 20.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 KOS12635.1 - 0.00055 19.1 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KOS12635.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase CN_hydrolase PF00795.17 KOS12636.1 - 6.4e-25 87.5 0.0 1.2e-24 86.6 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Abhydrolase_2 PF02230.11 KOS12637.1 - 4.9e-13 49.0 0.0 6.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KOS12637.1 - 0.0017 18.3 1.3 0.0026 17.6 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 KOS12638.1 - 4.7e-44 149.8 0.0 6.7e-43 146.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS12638.1 - 6.5e-27 93.2 0.1 1.3e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS12638.1 - 0.0079 16.0 0.0 0.024 14.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_1 PF00561.15 KOS12639.1 - 5.4e-23 81.7 0.1 6.6e-22 78.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS12639.1 - 4.4e-05 23.4 0.3 9.2e-05 22.4 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KOS12639.1 - 0.0028 17.5 0.0 0.0073 16.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Pkinase PF00069.20 KOS12640.1 - 2.1e-55 187.6 0.0 2.8e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12640.1 - 3.5e-29 101.6 0.0 5e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS12640.1 - 7.8e-06 25.7 4.1 9.7e-05 22.2 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS12640.1 - 4.7e-05 22.4 0.0 8.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KOS12640.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KOS12640.1 - 0.023 13.7 0.2 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCA2 PF08637.5 KOS12640.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 HMG_box PF00505.14 KOS12641.1 - 5.6e-25 87.3 11.8 5.6e-14 52.1 1.2 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS12641.1 - 6.6e-18 64.8 8.7 1.3e-09 38.2 1.0 2.4 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 KOS12641.1 - 0.047 13.3 0.1 0.36 10.5 0.0 2.3 1 1 1 2 2 2 0 CHDNT (NUC034) domain RNase_T PF00929.19 KOS12642.1 - 7.3e-14 52.3 0.0 4.2e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Exonuclease CagE_TrbE_VirB PF03135.9 KOS12642.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system CHORD PF04968.7 KOS12642.1 - 0.088 13.0 0.9 0.34 11.1 0.6 2.0 1 1 0 1 1 1 0 CHORD ECH PF00378.15 KOS12643.1 - 1.6e-35 122.4 0.2 2.3e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KOS12643.1 - 0.025 14.7 0.1 0.041 14.0 0.1 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Abhydrolase_6 PF12697.2 KOS12643.1 - 0.13 12.1 1.5 0.38 10.5 1.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DAGAT PF03982.8 KOS12644.1 - 5.1e-99 330.7 0.0 5.9e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RCC1 PF00415.13 KOS12645.1 - 1.9e-54 181.6 8.6 2.9e-10 40.1 0.1 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS12645.1 - 3.8e-38 128.3 28.9 5.2e-09 35.4 0.2 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Mg_trans_NIPA PF05653.9 KOS12646.1 - 7e-23 81.0 8.5 7.1e-12 44.8 0.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA BRCT PF00533.21 KOS12647.1 - 5e-31 106.6 0.1 1.7e-08 34.4 0.0 4.9 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KOS12647.1 - 2.2e-27 94.6 8.8 3.2e-14 52.5 0.0 5.1 6 0 0 6 6 6 3 twin BRCT domain Sec1 PF00995.18 KOS12648.1 - 1.4e-133 446.5 0.0 3e-133 445.4 0.0 1.5 1 1 0 1 1 1 1 Sec1 family DASH_Hsk3 PF08227.6 KOS12648.1 - 1.6e-06 28.1 0.5 5.6e-06 26.4 0.3 2.0 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like RhoGEF PF00621.15 KOS12649.1 - 9.6e-37 126.5 1.0 9.6e-37 126.5 0.7 2.5 3 0 0 3 3 3 1 RhoGEF domain Halogen_Hydrol PF10112.4 KOS12649.1 - 0.059 12.7 3.2 1.7 8.0 0.2 2.4 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein IKI3 PF04762.7 KOS12650.1 - 1.2e-236 787.8 0.0 6.6e-236 785.4 0.0 1.8 2 0 0 2 2 2 1 IKI3 family Se-cys_synth_N PF12390.3 KOS12650.1 - 0.048 13.7 2.2 0.19 11.8 0.1 3.2 3 0 0 3 3 3 0 Selenocysteine synthase N terminal FF PF01846.14 KOS12651.1 - 1e-21 76.6 15.7 3e-05 23.8 0.0 6.5 6 1 0 6 6 6 5 FF domain Hydant_A_N PF05378.8 KOS12651.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Rgp1 PF08737.5 KOS12653.1 - 9.4e-63 212.7 0.0 7.5e-62 209.7 0.0 2.4 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 KOS12653.1 - 0.0016 18.5 0.0 2.5 8.1 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KOS12653.1 - 0.003 17.4 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Cnd2 PF05786.9 KOS12654.1 - 6.5e-135 451.4 9.0 4e-133 445.5 6.2 2.7 1 1 0 1 1 1 1 Condensin complex subunit 2 Sulfate_transp PF00916.15 KOS12655.1 - 1.6e-78 263.5 6.6 1.6e-78 263.5 4.5 2.1 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KOS12655.1 - 1.1e-28 98.6 4.1 1.1e-28 98.6 2.8 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KOS12655.1 - 6.1e-09 35.3 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KOS12655.1 - 0.004 17.1 0.3 0.004 17.1 0.2 2.1 2 0 0 2 2 2 1 STAS domain SNN_transmemb PF09049.5 KOS12655.1 - 0.045 13.4 0.5 0.045 13.4 0.3 3.3 4 0 0 4 4 4 0 Stannin transmembrane CDC27 PF09507.5 KOS12656.1 - 1.1e-39 136.8 5.9 1.4e-21 77.2 2.5 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 DUF1838 PF08894.6 KOS12656.1 - 0.067 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) Thioredoxin_6 PF13848.1 KOS12656.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain COX6A PF02046.10 KOS12657.1 - 2.4e-30 104.8 0.1 2.8e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa HABP4_PAI-RBP1 PF04774.10 KOS12658.1 - 0.00016 22.0 14.7 0.00016 22.0 10.2 3.6 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family TSP9 PF11493.3 KOS12658.1 - 0.042 14.3 1.8 0.042 14.3 1.2 3.0 3 1 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 Vfa1 PF08432.5 KOS12658.1 - 1.4 8.8 7.9 2.3 8.1 5.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 adh_short PF00106.20 KOS12659.1 - 0.013 15.4 2.9 2.5 7.9 0.1 3.3 2 1 0 3 3 3 0 short chain dehydrogenase KAT11 PF08214.6 KOS12660.1 - 4.1e-37 128.0 0.0 5.4e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cyt-b5 PF00173.23 KOS12661.1 - 3e-21 75.0 0.0 6.2e-21 73.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain GTP_EFTU PF00009.22 KOS12662.1 - 2.6e-47 160.7 0.0 3.8e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KOS12662.1 - 3.3e-38 129.9 0.2 6.3e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KOS12662.1 - 4.1e-10 39.4 0.0 9.8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KOS12662.1 - 1.1e-06 28.3 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KOS12662.1 - 3.5e-05 23.8 0.1 6.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS12662.1 - 6.9e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KOS12662.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.5 KOS12662.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KOS12662.1 - 0.081 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TPR_11 PF13414.1 KOS12664.1 - 1.3e-17 63.2 2.4 1.1e-13 50.5 1.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KOS12664.1 - 1.1e-11 43.7 5.3 0.0044 16.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS12664.1 - 5.1e-11 41.6 4.7 0.0056 16.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS12664.1 - 2.5e-06 27.7 2.1 0.00022 21.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS12664.1 - 3.9e-06 27.3 9.8 0.002 18.7 1.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS12664.1 - 4.8e-06 26.4 2.1 0.001 18.9 0.3 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS12664.1 - 1.8e-05 24.8 0.5 3.9e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KOS12664.1 - 0.00015 22.0 3.7 0.086 13.5 0.1 4.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS12664.1 - 0.0022 17.6 0.6 0.92 9.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS12664.1 - 0.012 15.7 0.2 3.3 8.1 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS12664.1 - 0.013 15.3 0.8 12 5.9 0.0 3.3 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 KOS12664.1 - 0.023 14.4 0.3 31 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PsiA PF06952.6 KOS12664.1 - 0.11 11.5 1.5 0.16 10.9 1.1 1.2 1 0 0 1 1 1 0 PsiA protein TPR_10 PF13374.1 KOS12664.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Bromodomain PF00439.20 KOS12665.1 - 1.6e-35 120.8 0.1 2.2e-18 65.9 0.0 2.8 2 1 0 2 2 2 2 Bromodomain CNH PF00780.17 KOS12666.1 - 3.9e-36 124.9 0.0 1.3e-35 123.1 0.0 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 KOS12666.1 - 2e-25 89.7 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain TIMELESS PF04821.9 KOS12667.1 - 7.1e-48 163.1 0.1 1.4e-47 162.2 0.1 1.5 1 0 0 1 1 1 1 Timeless protein OPT PF03169.10 KOS12667.1 - 0.046 12.1 0.3 0.074 11.4 0.2 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein PAT1 PF09770.4 KOS12668.1 - 2.1e-165 552.2 0.0 2.5e-165 551.9 0.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2611 PF11022.3 KOS12669.1 - 4.2e-18 65.1 0.1 4.7e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AalphaY_MDB PF04611.7 KOS12669.1 - 0.071 12.9 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Ribosomal_L35p PF01632.14 KOS12670.1 - 1.5e-05 24.7 1.9 0.0001 22.1 1.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L35 zf-UBR PF02207.15 KOS12671.1 - 6.2e-15 54.6 14.6 6.2e-15 54.6 10.1 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KOS12671.1 - 2.1e-08 33.7 0.0 6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PLA2_B PF01735.13 KOS12672.1 - 7e-151 502.7 1.7 8.4e-151 502.4 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.17 KOS12672.1 - 1.4e-05 25.1 0.0 3.9e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase TRAPP PF04051.11 KOS12674.1 - 6.4e-29 100.4 0.0 7.9e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2378 PF09536.5 KOS12674.1 - 0.016 14.7 0.1 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) DUF4164 PF13747.1 KOS12674.1 - 0.072 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DCP1 PF06058.8 KOS12675.1 - 2.1e-22 79.4 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family PI-PLC-X PF00388.14 KOS12676.1 - 4.3e-53 178.6 0.0 9.3e-53 177.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KOS12676.1 - 6.2e-34 116.5 0.0 1.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KOS12676.1 - 1e-06 28.6 0.0 1e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 KOS12676.1 - 0.0052 16.3 0.0 0.055 13.0 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair C2 PF00168.25 KOS12676.1 - 0.019 14.7 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 C2 domain TIP120 PF08623.5 KOS12677.1 - 4.1e-39 133.8 0.7 2.8e-38 131.1 0.1 2.6 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KOS12677.1 - 2.9e-08 33.8 51.8 0.0088 16.2 0.1 11.1 7 4 3 11 11 11 6 HEAT repeats Adaptin_N PF01602.15 KOS12677.1 - 1.9e-05 23.1 8.9 0.078 11.2 0.5 4.0 3 1 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.2 KOS12677.1 - 0.00028 20.7 3.6 0.75 9.6 0.0 4.2 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KOS12677.1 - 0.013 15.4 41.2 1.2 9.4 0.0 11.9 13 0 0 13 13 13 0 HEAT repeat V-ATPase_H_N PF03224.9 KOS12677.1 - 0.18 10.9 3.3 5.3 6.0 0.1 3.9 3 1 0 3 3 3 0 V-ATPase subunit H CLASP_N PF12348.3 KOS12677.1 - 0.22 10.8 9.1 4.4 6.6 0.0 5.8 7 1 1 8 8 8 0 CLASP N terminal Arm PF00514.18 KOS12677.1 - 4.3 7.3 11.9 87 3.1 0.0 6.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Gag_p12 PF01141.13 KOS12678.1 - 0.059 13.4 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 DUF572 PF04502.8 KOS12678.1 - 0.3 10.2 10.2 0.33 10.1 7.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) VID27 PF08553.5 KOS12679.1 - 3.2e-277 921.9 0.0 4.4e-276 918.2 0.0 1.9 1 1 0 1 1 1 1 VID27 cytoplasmic protein PPP4R2 PF09184.6 KOS12679.1 - 0.2 11.1 6.4 0.07 12.6 2.7 1.5 2 0 0 2 2 2 0 PPP4R2 PCI_Csn8 PF10075.4 KOS12680.1 - 1.3e-31 109.3 0.1 2.5e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KOS12680.1 - 8.8e-29 100.5 0.1 1.3e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Aldedh PF00171.17 KOS12681.1 - 1.3e-122 409.4 0.0 1.7e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arm PF00514.18 KOS12682.1 - 1.9e-69 227.3 26.9 2.5e-11 42.9 0.0 11.5 11 1 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KOS12682.1 - 1.9e-21 76.1 13.9 7.8e-06 26.0 0.0 7.1 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 KOS12682.1 - 2.6e-15 56.3 12.9 0.093 13.2 0.2 8.9 7 3 2 9 9 9 5 HEAT-like repeat HEAT PF02985.17 KOS12682.1 - 3.2e-15 54.7 20.4 1.2 9.3 0.0 10.3 11 0 0 11 11 11 6 HEAT repeat Adaptin_N PF01602.15 KOS12682.1 - 7.5e-11 41.0 7.5 2.3e-07 29.5 0.5 2.5 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KOS12682.1 - 5.7e-09 35.4 6.2 5.5e-05 22.4 1.8 3.9 3 1 2 5 5 5 3 Armadillo-like KAP PF05804.7 KOS12682.1 - 5.6e-08 31.1 0.1 1.3e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KOS12682.1 - 1.8e-07 30.5 3.6 0.0056 15.8 0.3 4.5 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 KOS12682.1 - 0.008 16.0 1.4 10 6.0 0.0 3.8 2 1 2 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 KOS12682.1 - 0.03 14.7 11.4 18 6.1 0.1 7.2 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat Ribosomal_L13 PF00572.13 KOS12683.1 - 2e-26 92.5 0.0 3.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 BBP1_C PF15272.1 KOS12683.1 - 0.0083 15.6 0.2 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Aminotran_1_2 PF00155.16 KOS12684.1 - 2.2e-45 155.1 0.0 1.3e-42 146.0 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KOS12684.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KOS12684.1 - 0.003 16.1 0.0 0.0051 15.4 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DEAD PF00270.24 KOS12685.1 - 6.7e-33 113.5 0.2 2e-31 108.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS12685.1 - 4.7e-26 90.4 0.2 8.4e-26 89.6 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KOS12685.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_30 PF13604.1 KOS12685.1 - 0.029 13.9 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain PUF PF00806.14 KOS12686.1 - 7.8e-66 214.0 15.5 7.1e-09 34.6 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Gtr1_RagA PF04670.7 KOS12686.1 - 0.048 12.8 0.7 0.078 12.1 0.2 1.5 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region Peptidase_M24 PF00557.19 KOS12687.1 - 6.2e-32 110.8 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KOS12687.1 - 1.4e-18 67.6 0.0 1e-15 58.4 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Phage_int_SAM_1 PF02899.12 KOS12687.1 - 2.4 8.3 7.0 0.95 9.6 0.3 3.4 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain AAA PF00004.24 KOS12688.1 - 3.7e-52 176.0 0.1 3.5e-39 134.0 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KOS12688.1 - 5.6e-09 36.1 0.0 3.1e-05 23.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KOS12688.1 - 7.4e-09 35.8 0.3 0.00053 20.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KOS12688.1 - 1.9e-08 33.8 1.3 5.3e-07 29.1 0.3 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 KOS12688.1 - 1.4e-07 30.5 0.1 0.013 14.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KOS12688.1 - 1.8e-07 31.3 0.1 0.0066 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KOS12688.1 - 3e-07 30.2 0.2 0.0011 18.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KOS12688.1 - 1e-06 28.6 0.0 0.037 13.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KOS12688.1 - 1.1e-06 29.4 0.0 0.0065 17.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS12688.1 - 1.3e-06 28.0 0.5 0.077 12.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 KOS12688.1 - 2.1e-06 26.9 0.4 0.012 14.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KOS12688.1 - 4.5e-06 25.9 0.2 0.0037 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KOS12688.1 - 9e-06 25.6 0.0 0.09 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KOS12688.1 - 1.1e-05 24.9 0.1 0.035 13.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KOS12688.1 - 1.3e-05 24.7 0.5 0.2 11.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain NACHT PF05729.7 KOS12688.1 - 1.3e-05 24.9 0.9 0.02 14.5 0.0 3.2 3 1 1 4 4 4 1 NACHT domain AAA_18 PF13238.1 KOS12688.1 - 1.4e-05 25.3 0.1 0.019 15.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain PhoH PF02562.11 KOS12688.1 - 2.1e-05 23.8 0.0 0.043 13.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein RNA_helicase PF00910.17 KOS12688.1 - 2.9e-05 24.1 0.0 0.041 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 KOS12688.1 - 3.1e-05 23.6 0.1 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KOS12688.1 - 7.1e-05 22.3 0.1 0.42 10.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KOS12688.1 - 8.9e-05 22.7 0.1 0.13 12.6 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 KOS12688.1 - 0.00014 21.5 2.7 0.049 13.2 0.1 2.7 2 1 0 2 2 2 2 AAA domain KaiC PF06745.8 KOS12688.1 - 0.00015 20.9 0.0 0.0053 15.9 0.0 2.6 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 KOS12688.1 - 0.00042 19.2 0.1 0.76 8.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KOS12688.1 - 0.00078 19.2 0.5 7.2 6.2 0.0 3.9 3 2 2 5 5 4 0 Archaeal ATPase UPF0079 PF02367.12 KOS12688.1 - 0.00083 18.9 0.1 0.41 10.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 KOS12688.1 - 0.0013 18.8 0.2 4.2 7.4 0.1 3.6 3 1 0 3 3 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 KOS12688.1 - 0.0015 17.5 0.1 0.22 10.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 KOS12688.1 - 0.0018 17.9 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KOS12688.1 - 0.0021 16.9 0.2 1.5 7.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain CDC48_N PF02359.13 KOS12688.1 - 0.003 17.4 0.0 0.0085 16.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.7 KOS12688.1 - 0.0033 16.5 0.1 0.89 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 KOS12688.1 - 0.0046 16.5 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KOS12688.1 - 0.0047 16.9 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KOS12688.1 - 0.012 15.3 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.4 KOS12688.1 - 0.014 14.3 0.0 0.95 8.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 KOS12688.1 - 0.03 13.2 0.0 4.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 KOS12688.1 - 0.049 12.6 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.1 KOS12688.1 - 0.069 12.6 0.3 3 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 KOS12688.1 - 0.23 10.6 0.1 0.55 9.3 0.0 1.6 2 0 0 2 2 1 0 Chromatin associated protein KTI12 Ribosomal_L24e PF01246.15 KOS12689.1 - 2.6e-33 113.7 0.6 2.6e-33 113.7 0.4 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e FRG2 PF15315.1 KOS12690.1 - 0.041 13.8 10.4 0.067 13.1 7.2 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 RP-C_C PF11800.3 KOS12690.1 - 0.15 11.7 4.0 0.27 10.9 2.7 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region ACT_3 PF10000.4 KOS12691.1 - 1.1e-19 69.8 0.1 2.1e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KOS12691.1 - 5.5e-13 48.2 0.0 7.9e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 ACT domain Ran_BP1 PF00638.13 KOS12692.1 - 2.1e-21 76.2 0.0 5.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KOS12692.1 - 7.5e-06 25.6 0.1 2.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 WH1 domain SIS PF01380.17 KOS12693.1 - 1.1e-15 57.4 0.0 6.9e-15 54.8 0.0 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KOS12693.1 - 0.00024 20.8 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 SIS domain ADH_zinc_N PF00107.21 KOS12693.1 - 0.099 12.1 0.1 17 4.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF4499 PF14934.1 KOS12694.1 - 3.5e-10 39.6 0.1 3.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) SPT2 PF08243.6 KOS12695.1 - 4e-17 62.5 15.5 4e-17 62.5 10.7 4.1 3 1 1 4 4 4 1 SPT2 chromatin protein GAS PF13851.1 KOS12695.1 - 0.59 9.2 16.7 1.3 8.1 11.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lipase_3 PF01764.20 KOS12696.1 - 8.8e-24 83.7 0.0 1.1e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KOS12696.1 - 3.5e-07 30.3 0.1 4.1e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KOS12696.1 - 7.7e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KOS12696.1 - 1.9e-05 24.4 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS12696.1 - 0.0038 16.7 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KOS12696.1 - 0.0059 16.1 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KOS12696.1 - 0.0091 15.4 0.1 0.027 13.9 0.1 1.7 1 1 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.8 KOS12696.1 - 0.011 14.0 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_8 PF06259.7 KOS12696.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 KOS12696.1 - 0.03 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.9 KOS12696.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 KOS12696.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.17 KOS12697.1 - 2.4e-17 62.3 0.0 4.9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS12697.1 - 6e-12 45.3 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS12697.1 - 2.9e-09 36.6 0.0 5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIN1 PF05422.7 KOS12698.1 - 1e-18 67.2 0.3 1.2e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 KOS12698.1 - 0.00036 20.9 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.5 KOS12698.1 - 0.004 17.1 0.0 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain DUF1517 PF07466.6 KOS12698.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) LIP PF03583.9 KOS12699.1 - 2.1e-60 204.4 0.1 2.5e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.11 KOS12699.1 - 0.0087 15.5 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Brr6_like_C_C PF10104.4 KOS12700.1 - 1.9e-40 137.5 0.2 2.3e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3395 PF11875.3 KOS12701.1 - 2e-33 115.1 0.0 3.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KOS12701.1 - 1.5e-21 75.8 1.8 2.7e-21 75.0 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4376 PF14301.1 KOS12701.1 - 0.087 12.9 0.8 2.9 8.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) HSD3 PF15244.1 KOS12701.1 - 0.1 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase DBD_Tnp_Mut PF03108.10 KOS12702.1 - 3.2e-05 23.4 0.0 0.00024 20.5 0.0 2.3 3 0 0 3 3 3 1 MuDR family transposase MULE PF10551.4 KOS12702.1 - 9.5e-05 22.5 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 KOS12702.1 - 0.0043 16.4 0.3 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_2 PF13696.1 KOS12702.1 - 0.1 12.1 2.0 0.17 11.3 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle PAPS_reduct PF01507.14 KOS12703.1 - 3.3e-17 62.8 0.0 5.8e-15 55.5 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.20 KOS12704.1 - 4.7e-24 84.9 0.0 7.9e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KOS12704.1 - 1.4e-15 55.8 11.1 0.0002 21.1 0.0 7.0 7 0 0 7 7 6 3 HEAT repeat WD40 PF00400.27 KOS12704.1 - 1.2e-14 53.5 26.3 2.5e-09 36.6 0.6 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT_2 PF13646.1 KOS12704.1 - 4.5e-10 39.6 1.7 0.00047 20.3 0.2 4.5 2 1 2 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 KOS12704.1 - 3.2e-09 36.2 0.0 2.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_EZ PF13513.1 KOS12704.1 - 3.1e-05 24.2 3.1 0.93 10.0 0.0 5.5 5 1 1 6 6 4 1 HEAT-like repeat Adaptin_N PF01602.15 KOS12704.1 - 0.00018 19.9 0.1 0.3 9.3 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 KOS12704.1 - 0.00088 19.1 0.0 5.7 6.7 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KOS12704.1 - 0.0066 16.3 0.1 4.3 7.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 KOS12704.1 - 0.027 14.4 0.9 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.1 KOS12704.1 - 0.035 13.5 0.1 1 8.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) IFRD PF05004.8 KOS12704.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Pox_TAP PF03355.9 KOS12704.1 - 0.4 9.9 0.0 0.68 9.2 0.0 1.2 1 0 0 1 1 1 0 Viral Trans-Activator Protein HMGL-like PF00682.14 KOS12705.1 - 2e-71 240.3 0.6 4.1e-71 239.4 0.4 1.5 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 KOS12705.1 - 0.066 11.7 0.0 7.3 5.0 0.0 2.5 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Nol1_Nop2_Fmu PF01189.12 KOS12706.1 - 2.2e-90 302.8 0.0 4.2e-90 301.9 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 KOS12706.1 - 0.0033 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 KOS12706.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 KOS12706.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CDP-OH_P_transf PF01066.16 KOS12707.1 - 2.1e-19 69.7 2.8 2.1e-19 69.7 2.0 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ORMDL PF04061.9 KOS12708.1 - 7.2e-54 181.0 3.9 1.1e-53 180.4 2.7 1.2 1 0 0 1 1 1 1 ORMDL family Aldo_ket_red PF00248.16 KOS12709.1 - 1.5e-104 348.8 0.2 2.6e-51 174.1 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Ribosomal_S5 PF00333.15 KOS12709.1 - 0.01 15.5 0.0 6.7 6.5 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain RHH_1 PF01402.16 KOS12709.1 - 0.018 14.9 1.8 1.4 8.9 0.0 3.6 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family LSM PF01423.17 KOS12710.1 - 6.6e-17 60.8 0.2 8.6e-17 60.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS12710.1 - 0.00017 21.4 0.1 0.00023 21.0 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain GRDB PF07355.7 KOS12710.1 - 0.087 11.7 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Rap_GAP PF02145.10 KOS12711.1 - 3.1e-48 163.6 0.0 5.5e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 KOS12711.1 - 6.5e-34 117.1 0.0 1.2e-30 106.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Tuberin PF03542.11 KOS12711.1 - 1.2e-27 96.8 11.7 7.9e-24 84.3 2.4 3.9 3 1 0 3 3 3 2 Tuberin Glyco_tran_28_C PF04101.11 KOS12711.1 - 4.6e-15 55.6 0.0 1.2e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HEAT PF02985.17 KOS12712.1 - 9.4e-06 25.2 12.3 0.065 13.3 0.1 7.4 6 0 0 6 6 6 3 HEAT repeat CRM1_C PF08767.6 KOS12712.1 - 1.1 8.1 0.0 10 4.9 0.0 2.2 2 0 0 2 2 2 0 CRM1 C terminal Adaptin_N PF01602.15 KOS12712.1 - 2.5 6.3 4.9 1.2 7.3 0.1 2.7 4 0 0 4 4 4 0 Adaptin N terminal region Glyco_hydro_47 PF01532.15 KOS12713.1 - 2.8e-145 484.4 0.0 3.5e-145 484.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 T2SM_b PF10741.4 KOS12713.1 - 0.02 14.5 0.4 0.037 13.6 0.3 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Acetyltransf_1 PF00583.19 KOS12714.1 - 1.8e-13 50.3 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS12714.1 - 1.1e-07 31.9 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KOS12714.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS12714.1 - 0.0012 18.5 0.7 0.0033 17.1 0.1 2.0 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KOS12714.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS12714.1 - 0.0019 18.1 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS12714.1 - 0.0056 16.6 0.0 0.0076 16.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_pol_B PF00136.16 KOS12715.1 - 9.6e-148 492.8 0.1 1.4e-147 492.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KOS12715.1 - 1.5e-84 283.6 0.0 5.3e-84 281.8 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KOS12715.1 - 1.4e-22 79.4 9.4 2.7e-22 78.5 6.5 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KOS12715.1 - 0.023 14.5 0.2 0.082 12.7 0.1 2.0 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KOS12715.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 KOS12715.1 - 0.11 11.1 2.7 0.14 10.8 0.1 2.2 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral Pyr_redox_3 PF13738.1 KOS12716.1 - 2.2e-21 76.8 0.1 4.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS12716.1 - 2.9e-21 75.3 0.3 1.9e-20 72.6 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KOS12716.1 - 4.6e-12 45.7 1.0 1.2e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS12716.1 - 1.5e-11 44.5 0.5 2.6e-05 24.2 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS12716.1 - 1.4e-10 41.4 2.6 0.00023 21.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS12716.1 - 2.1e-09 36.7 0.0 5.6e-07 28.7 0.0 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KOS12716.1 - 2.8e-08 33.0 0.5 2.9e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KOS12716.1 - 2.4e-06 27.3 0.7 0.00043 20.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KOS12716.1 - 3.1e-06 26.4 2.6 0.0047 16.0 0.5 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KOS12716.1 - 1.9e-05 23.3 4.3 0.0095 14.4 0.4 2.5 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.19 KOS12716.1 - 3.3e-05 23.1 0.1 0.00014 21.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 KOS12716.1 - 4e-05 23.7 0.1 0.0039 17.4 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 KOS12716.1 - 4.7e-05 22.6 0.6 0.19 10.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KOS12716.1 - 9e-05 22.5 0.3 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KOS12716.1 - 0.00038 19.4 5.3 0.078 11.8 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KOS12716.1 - 0.00048 19.0 8.4 0.0041 16.0 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 KOS12716.1 - 0.00049 19.2 2.4 0.032 13.3 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 KOS12716.1 - 0.0028 17.3 2.2 0.0046 16.6 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KOS12716.1 - 0.0047 16.5 1.1 0.88 9.1 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KOS12716.1 - 0.029 14.1 0.5 7.6 6.3 0.0 2.6 3 0 0 3 3 2 0 ThiF family NAD_binding_10 PF13460.1 KOS12716.1 - 0.036 14.0 2.2 0.63 10.0 0.2 2.4 2 0 0 2 2 2 0 NADH(P)-binding Lycopene_cycl PF05834.7 KOS12716.1 - 0.2 10.5 1.3 0.57 9.0 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KOS12716.1 - 0.21 10.9 0.6 0.49 9.7 0.3 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Malic_M PF03949.10 KOS12716.1 - 0.33 10.4 1.1 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Peptidase_S10 PF00450.17 KOS12717.1 - 9.6e-91 304.9 0.0 1.1e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KOS12717.1 - 5.2e-06 26.5 1.7 2.7e-05 24.1 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS12717.1 - 0.0018 18.0 0.0 0.005 16.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_pol_Rpb2_6 PF00562.23 KOS12718.1 - 1.5e-111 372.8 0.0 2e-111 372.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS12718.1 - 3.5e-31 107.7 0.0 4.8e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KOS12718.1 - 6.7e-24 83.4 0.0 1.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 KOS12718.1 - 4.4e-23 81.6 0.0 6.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 KOS12718.1 - 1.1e-21 76.4 0.0 2.2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KOS12718.1 - 8.5e-16 57.9 0.0 1.5e-14 54.0 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KOS12718.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 KH_1 PF00013.24 KOS12719.1 - 0.00014 21.4 0.9 0.00034 20.2 0.4 1.7 2 0 0 2 2 2 1 KH domain Porin_3 PF01459.17 KOS12720.1 - 1.3e-66 224.6 0.2 1.6e-66 224.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2460 PF09343.5 KOS12720.1 - 0.014 14.7 0.2 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) PAH PF02671.16 KOS12721.1 - 2.9e-46 154.8 2.1 2e-18 65.6 1.1 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KOS12721.1 - 1.4e-38 130.6 0.0 3.3e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor YjeF_N PF03853.10 KOS12722.1 - 6.2e-32 110.5 0.0 7.3e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus CLASP_N PF12348.3 KOS12723.1 - 4.3e-30 104.7 0.2 2.3e-08 33.6 0.0 6.2 7 0 0 7 7 7 5 CLASP N terminal HEAT PF02985.17 KOS12723.1 - 2.2e-15 55.2 29.1 0.00061 19.6 0.0 12.8 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.1 KOS12723.1 - 4.4e-13 49.3 44.0 7e-05 23.0 0.1 12.9 10 4 2 12 12 12 4 HEAT repeats HEAT_EZ PF13513.1 KOS12723.1 - 0.0002 21.7 0.2 0.0002 21.7 0.1 9.9 9 2 1 10 10 10 1 HEAT-like repeat Adaptin_N PF01602.15 KOS12723.1 - 0.00035 19.0 0.0 1.9 6.7 0.0 4.3 4 1 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 KOS12723.1 - 0.00043 20.1 0.0 16 5.2 0.0 6.0 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KOS12723.1 - 0.0015 16.9 0.1 0.032 12.4 0.0 3.0 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit DUF2435 PF10363.4 KOS12723.1 - 0.015 15.1 4.1 53 3.8 0.0 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) DUF4391 PF14335.1 KOS12723.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) TFIIF_alpha PF05793.7 KOS12723.1 - 0.93 7.7 0.3 1.9 6.7 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lon_C PF05362.8 KOS12724.1 - 1.2e-67 227.2 0.1 2.4e-67 226.2 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KOS12724.1 - 3.7e-33 114.9 1.2 3.7e-33 114.9 0.9 2.1 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KOS12724.1 - 9.5e-22 77.6 0.0 2.7e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KOS12724.1 - 3.4e-07 29.7 0.0 9.6e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KOS12724.1 - 1e-06 28.5 0.0 2.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KOS12724.1 - 2.4e-06 27.5 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS12724.1 - 4.6e-06 26.7 0.1 0.00071 19.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.6 KOS12724.1 - 2.1e-05 23.3 0.1 5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_17 PF13207.1 KOS12724.1 - 6.6e-05 23.7 0.1 0.00028 21.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KOS12724.1 - 0.00027 21.0 0.0 0.0074 16.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS12724.1 - 0.0011 18.0 0.0 0.0063 15.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS12724.1 - 0.0012 18.6 0.0 0.0035 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KOS12724.1 - 0.0016 17.1 0.3 0.27 9.9 0.1 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 KOS12724.1 - 0.0035 17.6 0.0 0.0035 17.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain ClpB_D2-small PF10431.4 KOS12724.1 - 0.014 15.2 0.1 0.014 15.2 0.1 3.0 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein SKI PF01202.17 KOS12724.1 - 0.015 15.2 1.4 0.09 12.6 0.0 2.9 3 0 0 3 3 2 0 Shikimate kinase DUF258 PF03193.11 KOS12724.1 - 0.025 13.7 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KOS12724.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KOS12724.1 - 0.036 13.4 0.0 0.094 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS12724.1 - 0.037 13.4 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KOS12724.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KOS12724.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KOS12724.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KOS12724.1 - 0.067 12.8 0.1 0.52 9.9 0.0 2.2 1 1 1 2 2 2 0 NTPase GUCT PF08152.7 KOS12724.1 - 0.091 12.7 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 1 0 GUCT (NUC152) domain AAA_3 PF07726.6 KOS12724.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KOS12724.1 - 0.14 12.4 1.6 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 KOS12724.1 - 0.16 11.8 0.1 1.2 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain Gag_p24 PF00607.15 KOS12725.1 - 0.1 12.1 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) SHR3_chaperone PF08229.6 KOS12726.1 - 1.3e-32 112.3 4.5 2.4e-32 111.4 3.1 1.4 1 1 0 1 1 1 1 ER membrane protein SH3 TctB PF07331.6 KOS12726.1 - 0.046 13.3 2.4 0.084 12.5 0.8 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3767 PF12597.3 KOS12726.1 - 0.066 12.8 0.1 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3767) ATP1G1_PLM_MAT8 PF02038.11 KOS12726.1 - 0.097 11.6 0.1 0.3 10.1 0.1 1.9 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF3816 PF12822.2 KOS12726.1 - 0.26 11.1 5.3 3.6 7.4 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Sdh_cyt PF01127.17 KOS12726.1 - 0.76 9.6 4.8 3.8 7.3 2.6 2.0 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Nop16 PF09420.5 KOS12727.1 - 1.5e-39 135.7 1.7 1.8e-39 135.4 1.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Dynactin_p62 PF05502.8 KOS12728.1 - 1.9e-59 201.7 27.5 1.7e-39 135.9 10.9 3.0 1 1 1 2 2 2 2 Dynactin p62 family Cupin_8 PF13621.1 KOS12729.1 - 2.2e-52 178.0 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KOS12729.1 - 0.011 15.0 0.8 0.21 10.7 0.1 2.6 2 0 0 2 2 2 0 Cupin superfamily protein PBP1_TM PF14812.1 KOS12729.1 - 9.5 6.6 7.3 28 5.1 0.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Y_phosphatase2 PF03162.8 KOS12730.1 - 4.2e-26 91.2 0.0 6.5e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family COesterase PF00135.23 KOS12732.1 - 9.7e-73 245.6 0.8 4.4e-71 240.2 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KOS12732.1 - 0.0043 16.6 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold UCH PF00443.24 KOS12733.1 - 1.4e-40 139.1 0.0 2.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS12733.1 - 5.8e-15 55.4 0.0 1.2e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KOS12733.1 - 8.7e-11 41.0 0.3 3.3e-10 39.2 0.1 2.1 2 0 0 2 2 2 1 A repeated domain in UCH-protein Glycos_transf_2 PF00535.21 KOS12734.1 - 5.8e-21 74.9 0.0 1.4e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KOS12734.1 - 1.2e-06 28.5 0.6 9.1e-05 22.3 0.1 2.6 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Usp PF00582.21 KOS12735.1 - 9.1e-14 51.8 0.8 1.9e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family DUF1777 PF08648.7 KOS12736.1 - 3.3e-18 66.0 0.1 3.6e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF3035 PF11233.3 KOS12736.1 - 0.15 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Nfu_N PF08712.6 KOS12737.1 - 3e-31 106.8 0.0 6.7e-31 105.7 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KOS12737.1 - 7.2e-22 76.9 1.0 1.3e-21 76.1 0.2 1.8 2 0 0 2 2 2 1 NifU-like domain ADK PF00406.17 KOS12738.1 - 2.9e-41 140.8 0.0 2.8e-40 137.6 0.0 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KOS12738.1 - 7.1e-10 39.2 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS12738.1 - 5.3e-07 30.4 0.0 7.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KOS12738.1 - 1.3e-06 27.9 0.1 4.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 KOS12738.1 - 4.8e-06 26.5 0.0 3.1e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF1397 PF07165.6 KOS12738.1 - 0.022 13.9 0.3 0.031 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) AAA PF00004.24 KOS12738.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.1 KOS12739.1 - 3.6e-35 120.5 0.1 1.3e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KOS12739.1 - 9.3e-29 99.4 0.1 2.2e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GATA PF00320.22 KOS12740.1 - 5e-14 51.3 4.1 1.3e-13 50.0 2.9 1.8 1 0 0 1 1 1 1 GATA zinc finger FYVE PF01363.16 KOS12740.1 - 0.33 10.8 2.9 2 8.3 2.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger YIF1 PF03878.10 KOS12741.1 - 3.5e-73 245.6 3.4 2.6e-52 177.3 1.4 2.0 2 0 0 2 2 2 2 YIF1 DUF814 PF05670.8 KOS12742.1 - 4.3e-20 71.3 0.1 1.2e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF814) AAA_23 PF13476.1 KOS12742.1 - 2 8.7 8.5 2.3 8.4 5.9 1.1 1 0 0 1 1 1 0 AAA domain LNS2 PF08235.8 KOS12743.1 - 9.7e-71 236.4 0.0 1.8e-70 235.5 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KOS12743.1 - 2.2e-27 94.9 0.1 3.7e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KOS12743.1 - 0.0055 16.1 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) RRM_1 PF00076.17 KOS12744.1 - 2.1e-82 270.7 2.2 4.8e-21 74.1 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS12744.1 - 3.5e-54 180.6 0.1 1.4e-13 50.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS12744.1 - 2.7e-41 139.2 0.3 7.6e-10 38.5 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KOS12744.1 - 1.7e-30 104.5 1.8 1.6e-29 101.3 1.2 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KOS12744.1 - 1.8e-05 24.3 1.3 2.9 7.6 0.1 4.5 3 1 1 4 4 4 2 Limkain b1 CbiG_mid PF11761.3 KOS12744.1 - 0.0038 17.4 1.1 3.3 7.9 0.0 3.2 4 0 0 4 4 4 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 KOS12744.1 - 0.015 15.0 0.3 18 5.2 0.0 3.9 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Snf7 PF03357.16 KOS12745.1 - 1.3e-33 115.8 21.8 2.3e-33 115.0 15.1 1.4 1 1 0 1 1 1 1 Snf7 Snapin_Pallidin PF14712.1 KOS12745.1 - 0.022 15.0 5.6 0.022 15.0 3.9 2.3 3 0 0 3 3 3 0 Snapin/Pallidin DivIC PF04977.10 KOS12745.1 - 0.49 9.9 5.5 5.6 6.5 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Cytochrom_B562 PF07361.6 KOS12745.1 - 0.62 10.5 9.5 0.33 11.3 0.3 3.0 2 1 0 2 2 2 0 Cytochrome b562 PspA_IM30 PF04012.7 KOS12745.1 - 1.2 8.4 18.4 4 6.7 2.6 2.4 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 KOS12745.1 - 1.5 8.8 12.7 0.58 10.1 4.4 2.2 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.7 KOS12745.1 - 2.1 8.0 9.8 4.1 7.1 6.7 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein eIF-1a PF01176.14 KOS12746.1 - 8.7e-25 85.9 0.1 1.4e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF1752 PF08550.5 KOS12747.1 - 4.1e-13 48.6 3.3 9.1e-13 47.5 2.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Sec16_C PF12931.2 KOS12748.1 - 2.6e-62 211.1 0.0 4e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KOS12748.1 - 2.5e-29 101.6 0.0 6.1e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TB2_DP1_HVA22 PF03134.14 KOS12749.1 - 9.4e-33 111.8 8.3 1.5e-32 111.2 5.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pro_isomerase PF00160.16 KOS12750.1 - 8.5e-41 139.7 0.0 1.7e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 KOS12750.1 - 0.0022 18.2 0.1 0.0022 18.2 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) YTH PF04146.10 KOS12751.1 - 1.4e-40 138.1 0.0 1.5e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 YT521-B-like domain ATP-synt_D PF01813.12 KOS12752.1 - 3.4e-64 216.0 0.6 5.3e-64 215.3 0.4 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Prefoldin PF02996.12 KOS12752.1 - 0.1 12.2 0.1 0.1 12.2 0.0 3.2 3 1 1 4 4 4 0 Prefoldin subunit eRF1_2 PF03464.10 KOS12753.1 - 6.5e-45 152.7 0.0 1.1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KOS12753.1 - 4.5e-39 133.2 0.1 9.1e-39 132.2 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KOS12753.1 - 2.6e-26 91.7 0.0 4.6e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Histone PF00125.19 KOS12754.1 - 6.5e-23 80.6 0.1 8.2e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS12754.1 - 0.0061 16.5 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF663 PF04950.7 KOS12755.1 - 6.6e-87 291.2 0.1 1.9e-86 289.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KOS12755.1 - 2.4e-20 71.8 0.0 7.4e-20 70.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF3793 PF12672.2 KOS12755.1 - 0.099 12.2 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Nop14 PF04147.7 KOS12755.1 - 9.3 4.0 23.7 14 3.3 16.4 1.2 1 0 0 1 1 1 0 Nop14-like family ABC_tran PF00005.22 KOS12756.1 - 6.2e-36 123.7 0.0 1.4e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KOS12756.1 - 1.8e-25 89.9 7.9 2.4e-25 89.4 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KOS12756.1 - 1.2e-07 31.9 0.1 0.0012 18.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KOS12756.1 - 1.8e-07 30.6 0.0 0.00027 20.2 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA PF00004.24 KOS12756.1 - 0.00022 21.4 0.0 0.0028 17.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KOS12756.1 - 0.0014 18.1 0.1 0.0036 16.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KOS12756.1 - 0.0017 18.2 0.0 0.022 14.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KOS12756.1 - 0.0059 16.6 0.1 0.016 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KOS12756.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KOS12756.1 - 0.015 15.4 0.0 0.068 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KOS12756.1 - 0.023 14.4 0.0 0.11 12.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KOS12756.1 - 0.036 13.2 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS12756.1 - 0.047 14.5 0.0 0.093 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KOS12756.1 - 0.1 12.5 1.4 1 9.3 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CLN3 PF02487.12 KOS12757.1 - 8.7e-64 215.7 9.8 5.1e-60 203.3 3.2 2.1 1 1 1 2 2 2 2 CLN3 protein DUF4491 PF14898.1 KOS12757.1 - 0.03 14.4 0.6 0.11 12.6 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) DUF4257 PF14074.1 KOS12757.1 - 0.074 12.7 1.5 0.41 10.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4257) DUF2562 PF10814.3 KOS12757.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DUF1129 PF06570.6 KOS12757.1 - 0.87 8.8 6.2 3.6 6.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) CNH PF00780.17 KOS12758.1 - 2.7e-79 266.4 0.0 4.1e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KOS12758.1 - 2.7e-45 153.6 0.1 4.9e-45 152.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KOS12758.1 - 1.2e-37 129.5 0.3 1.9e-37 128.8 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KOS12758.1 - 1e-11 44.3 0.1 2.3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dus PF01207.12 KOS12760.1 - 4e-43 147.4 0.1 8.1e-43 146.4 0.1 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) COX5A PF02284.11 KOS12760.1 - 0.14 12.0 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va ABC_membrane PF00664.18 KOS12761.1 - 4.6e-42 144.3 5.3 5.7e-42 144.0 3.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KOS12761.1 - 8.1e-31 107.1 0.0 1.4e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.4 KOS12761.1 - 2.4e-05 23.0 0.1 4.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KOS12761.1 - 0.00013 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KOS12761.1 - 0.00029 20.8 0.1 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KOS12761.1 - 0.0038 16.5 0.3 0.051 12.7 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS12761.1 - 0.0099 15.8 0.1 0.066 13.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS12761.1 - 0.045 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KOS12761.1 - 0.23 10.8 1.3 5.6 6.3 0.1 2.7 2 0 0 2 2 2 0 AAA-like domain EPSP_synthase PF00275.15 KOS12762.1 - 6.1e-127 423.5 0.1 1e-126 422.7 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KOS12762.1 - 2e-95 318.6 0.1 4.3e-95 317.5 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KOS12762.1 - 1.2e-60 204.9 0.0 2e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KOS12762.1 - 2.7e-27 94.6 0.0 6.1e-25 87.0 0.0 3.2 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KOS12762.1 - 4e-26 91.7 0.0 2e-24 86.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 KOS12762.1 - 3.4e-15 56.3 0.0 7.8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KOS12762.1 - 8e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KOS12762.1 - 0.00048 20.9 0.0 0.0019 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS12762.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KOS12762.1 - 1 8.4 0.0 1.6 7.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase zf-met2 PF12907.2 KOS12763.1 - 3.3e-18 65.3 0.5 4.5e-18 64.9 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KOS12763.1 - 1.1e-08 35.6 14.5 1.1e-08 35.6 10.1 1.9 2 0 0 2 2 2 1 4F5 protein family Ribosomal_L18p PF00861.17 KOS12763.1 - 0.0059 16.8 0.2 0.006 16.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Eapp_C PF10238.4 KOS12763.1 - 0.053 13.4 0.9 0.058 13.2 0.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4451 PF14616.1 KOS12763.1 - 0.065 13.0 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Cyto_heme_lyase PF01265.12 KOS12764.1 - 1.7e-63 214.6 0.6 2e-63 214.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Pkinase PF00069.20 KOS12765.1 - 8.3e-23 80.8 0.0 9.7e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12765.1 - 1.9e-09 36.9 0.0 2.9e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12765.1 - 0.0091 14.9 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pmp3 PF01679.12 KOS12766.1 - 1.5e-22 78.9 2.6 2e-22 78.6 1.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Hexapep PF00132.19 KOS12767.1 - 3.7e-07 29.3 1.1 0.0014 18.0 0.1 2.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS12767.1 - 0.00041 19.8 3.3 0.0022 17.5 1.3 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 KOS12767.1 - 0.018 14.3 0.0 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase CENP-I PF07778.6 KOS12768.1 - 2.4e-07 29.3 0.6 2.4e-07 29.3 0.4 1.8 3 0 0 3 3 3 1 Mis6 Opi1 PF08618.5 KOS12769.1 - 2e-39 135.7 4.8 2e-39 135.7 3.3 2.2 2 1 0 2 2 2 1 Transcription factor Opi1 AIP3 PF03915.8 KOS12769.1 - 0.00047 19.1 0.2 0.00091 18.2 0.0 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 Ferritin PF00210.19 KOS12769.1 - 0.016 14.9 0.3 0.58 9.9 0.1 2.5 2 1 0 2 2 2 0 Ferritin-like domain TFIIS_M PF07500.9 KOS12770.1 - 5.1e-19 68.4 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KOS12770.1 - 1.8e-10 40.3 10.2 3e-10 39.6 7.1 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 KOS12770.1 - 2.1e-10 41.1 0.0 3.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Nop14 PF04147.7 KOS12770.1 - 1.5e-05 23.1 17.8 2.5e-05 22.4 12.3 1.2 1 0 0 1 1 1 1 Nop14-like family MIP-T3 PF10243.4 KOS12770.1 - 0.0033 15.9 22.4 0.0033 15.9 14.9 1.5 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 KOS12770.1 - 0.033 13.2 17.8 0.074 12.1 12.4 1.5 1 0 0 1 1 1 0 BUD22 p450 PF00067.17 KOS12771.1 - 1.2e-62 211.9 0.5 2.3e-55 187.9 0.5 2.7 2 1 0 2 2 2 2 Cytochrome P450 Evr1_Alr PF04777.8 KOS12771.1 - 0.042 13.7 0.1 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Erv1 / Alr family WD40 PF00400.27 KOS12772.1 - 2.5e-08 33.4 0.1 9.9e-06 25.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat MBOAT_2 PF13813.1 KOS12772.1 - 1.1e-06 28.5 3.8 1e-05 25.4 2.6 2.7 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family BID PF06393.6 KOS12772.1 - 0.29 10.4 0.7 0.6 9.4 0.0 1.7 2 0 0 2 2 2 0 BH3 interacting domain (BID) NDUF_B4 PF07225.7 KOS12773.1 - 3.9e-05 23.4 0.0 4.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) NSs PF11073.3 KOS12773.1 - 0.015 14.5 0.1 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Arf PF00025.16 KOS12774.1 - 1.6e-70 235.8 0.0 1.8e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KOS12774.1 - 3.3e-12 46.1 0.0 3.7e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KOS12774.1 - 1.6e-10 40.5 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KOS12774.1 - 2.2e-10 39.7 0.0 5e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KOS12774.1 - 2e-09 36.9 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS12774.1 - 6.3e-05 23.4 0.0 8.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS12774.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 KOS12775.1 - 7e-10 38.5 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HAMP PF00672.20 KOS12776.1 - 2.7e-47 158.7 22.3 3.2e-08 33.6 0.1 8.2 7 1 0 7 7 7 7 HAMP domain Response_reg PF00072.19 KOS12776.1 - 4.2e-31 107.2 0.9 1.8e-27 95.5 0.2 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 KOS12776.1 - 5e-26 90.5 0.1 2e-25 88.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KOS12776.1 - 6.9e-18 64.4 0.4 1.1e-16 60.6 0.3 3.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 KOS12776.1 - 5.2e-05 22.6 0.3 0.4 10.5 0.0 4.0 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat Syntaxin PF00804.20 KOS12776.1 - 0.13 12.4 3.4 28 4.9 0.0 4.2 4 1 1 5 5 5 0 Syntaxin VBS PF08913.5 KOS12776.1 - 0.82 9.9 9.8 15 5.8 0.0 4.9 4 2 2 6 6 6 0 Vinculin Binding Site TMF_TATA_bd PF12325.3 KOS12776.1 - 2.6 7.8 7.7 5 6.8 0.0 4.1 5 0 0 5 5 5 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.20 KOS12777.1 - 1.9e-64 217.2 0.0 2.4e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12777.1 - 1.7e-42 145.2 0.0 2.3e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12777.1 - 7.9e-08 31.6 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KOS12777.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KOS12777.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KOS12777.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.24 KOS12778.1 - 1.2e-39 133.6 8.4 1.1e-14 53.8 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KOS12778.1 - 2.9e-29 100.1 14.9 2.6e-10 39.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KOS12778.1 - 2e-15 56.0 7.0 4.1e-06 26.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KOS12778.1 - 1.1e-08 34.6 3.9 0.011 15.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KOS12778.1 - 0.019 14.7 6.5 2 8.2 0.1 3.6 3 0 0 3 3 3 0 NusA-like KH domain GrpE PF01025.14 KOS12779.1 - 1.2e-41 142.0 0.2 1.5e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 GrpE DUF724 PF05266.9 KOS12779.1 - 0.0017 17.9 2.9 0.0024 17.5 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) HlyD_2 PF12700.2 KOS12779.1 - 0.018 14.2 0.3 0.02 14.0 0.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein IncA PF04156.9 KOS12779.1 - 0.3 10.6 2.6 0.38 10.3 1.8 1.2 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KOS12779.1 - 0.98 9.2 10.8 1.3 8.8 6.6 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Methyltransf_16 PF10294.4 KOS12780.1 - 1.3e-18 67.0 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 KOS12780.1 - 0.00068 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS12780.1 - 0.028 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12780.1 - 0.033 14.2 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Transp_cyt_pur PF02133.10 KOS12781.1 - 2.2e-37 128.6 34.1 3.8e-37 127.8 23.6 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UDPGT PF00201.13 KOS12782.1 - 6.7e-09 34.8 0.0 6.4e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KOS12782.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain DUF1987 PF09345.5 KOS12782.1 - 0.053 13.3 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) PGA_cap PF09587.5 KOS12782.1 - 0.056 12.7 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap RhoGAP PF00620.22 KOS12783.1 - 1.1e-37 128.9 0.1 2.8e-37 127.6 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain MIF4G PF02854.14 KOS12784.1 - 1.8e-41 141.8 0.0 3.7e-19 68.9 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KOS12784.1 - 0.012 15.4 19.6 0.038 13.7 13.6 1.9 1 1 0 1 1 1 0 Up-frameshift suppressor 2 Costars PF14705.1 KOS12784.1 - 0.054 13.4 0.0 0.21 11.5 0.0 2.1 1 0 0 1 1 1 0 Costars CDC45 PF02724.9 KOS12784.1 - 0.16 9.9 5.3 0.33 8.9 3.7 1.4 1 0 0 1 1 1 0 CDC45-like protein NOC3p PF07540.6 KOS12786.1 - 1.5e-22 79.6 0.0 4e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 KOS12786.1 - 2.1e-13 50.0 4.0 5.5e-13 48.6 0.0 2.9 3 0 0 3 3 3 1 CBF/Mak21 family SPX PF03105.14 KOS12786.1 - 0.021 14.6 2.7 0.049 13.4 1.8 1.7 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.7 KOS12786.1 - 4.4 5.1 30.2 7.7 4.3 20.9 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 KOS12786.1 - 9.2 4.7 7.8 18 3.8 5.4 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HAD_2 PF13419.1 KOS12787.1 - 2.2e-27 96.4 0.4 3e-27 95.9 0.3 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS12787.1 - 5.9e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS12787.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like CS PF04969.11 KOS12788.1 - 6.3e-06 26.6 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 CS domain LRR_6 PF13516.1 KOS12789.1 - 2.2e-20 70.3 0.1 0.46 10.7 0.1 9.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 KOS12789.1 - 1.9e-10 40.1 1.1 0.00013 21.5 0.1 5.7 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS12789.1 - 5.1e-08 31.8 7.3 6.7 7.1 0.0 7.9 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS12789.1 - 3.3e-07 29.4 14.0 5.3 7.6 0.1 9.3 9 0 0 9 9 9 1 Leucine rich repeat LRR_8 PF13855.1 KOS12789.1 - 0.0062 16.2 10.4 1.3 8.8 1.7 5.2 3 2 1 4 4 4 1 Leucine rich repeat Sad1_UNC PF07738.8 KOS12790.1 - 3e-27 95.0 0.0 3.9e-25 88.2 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal AAA_13 PF13166.1 KOS12790.1 - 0.036 12.5 1.6 0.057 11.8 1.1 1.2 1 0 0 1 1 1 0 AAA domain Flagellar_rod PF05149.7 KOS12790.1 - 0.053 12.7 4.5 0.093 11.9 3.1 1.4 1 0 0 1 1 1 0 Paraflagellar rod protein Spc7 PF08317.6 KOS12790.1 - 0.059 12.0 1.9 0.13 10.9 1.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KOS12790.1 - 0.072 12.6 3.1 0.63 9.6 2.2 2.2 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 KOS12790.1 - 0.17 11.0 1.5 0.37 9.9 1.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FH2 PF02181.18 KOS12790.1 - 0.32 9.8 3.8 2.3 7.0 0.1 2.2 1 1 0 2 2 2 0 Formin Homology 2 Domain MCPsignal PF00015.16 KOS12790.1 - 0.44 10.0 5.7 0.14 11.6 1.8 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TMF_TATA_bd PF12325.3 KOS12790.1 - 0.45 10.2 9.5 0.046 13.4 2.1 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 KOS12790.1 - 0.48 10.2 2.0 0.89 9.3 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 KOS12790.1 - 1.1 9.1 7.7 0.85 9.4 0.8 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 VSG_B PF13206.1 KOS12790.1 - 4.7 6.2 10.3 7.2 5.6 7.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1664 PF07889.7 KOS12790.1 - 5.5 6.7 5.8 1.4 8.7 0.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pyr_redox_2 PF07992.9 KOS12791.1 - 3e-25 89.2 0.1 3.8e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS12791.1 - 2.5e-16 59.8 0.6 8.7e-14 51.6 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS12791.1 - 4.1e-06 27.0 0.1 0.011 15.8 0.0 2.5 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS12791.1 - 3.7e-05 22.7 1.0 0.0094 14.8 0.1 3.4 4 1 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.12 KOS12791.1 - 7.6e-05 21.9 0.3 0.00084 18.5 0.0 2.3 2 1 1 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 KOS12791.1 - 0.00011 21.4 0.5 0.35 9.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KOS12791.1 - 0.00077 19.5 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KOS12791.1 - 0.0021 16.9 2.7 0.043 12.6 0.9 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KOS12791.1 - 0.0041 17.3 0.2 0.21 11.8 0.0 2.7 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KOS12791.1 - 0.0058 16.6 0.5 0.052 13.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KOS12791.1 - 0.0093 14.9 0.0 0.69 8.7 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KOS12791.1 - 0.013 14.1 0.4 0.056 12.0 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 KOS12791.1 - 0.014 14.4 0.4 0.081 11.9 0.1 2.0 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.19 KOS12791.1 - 0.026 13.4 2.8 0.063 12.1 0.2 2.5 1 1 2 4 4 4 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KOS12791.1 - 0.062 11.7 0.7 0.16 10.4 0.5 1.7 1 0 0 1 1 1 0 HI0933-like protein Helicase_C_3 PF13625.1 KOS12792.1 - 8.6e-28 96.6 0.0 2.3e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS12792.1 - 1.1e-14 54.6 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KOS12792.1 - 2.6e-14 52.7 0.2 4.2e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS12792.1 - 1.6e-11 43.8 0.1 6.3e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2360 PF10152.4 KOS12792.1 - 0.043 14.0 0.9 0.08 13.2 0.1 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AIP3 PF03915.8 KOS12793.1 - 7.7e-94 314.9 2.9 9.9e-94 314.6 2.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 FliL PF03748.9 KOS12793.1 - 0.0018 18.2 0.1 0.62 10.0 0.0 2.9 2 0 0 2 2 2 1 Flagellar basal body-associated protein FliL Syntaxin_2 PF14523.1 KOS12793.1 - 0.014 15.3 3.7 0.34 10.9 0.0 3.8 3 1 1 4 4 4 0 Syntaxin-like protein DUF948 PF06103.6 KOS12793.1 - 0.31 10.9 4.3 1 9.2 0.0 3.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KOS12793.1 - 1.1 9.3 4.7 36 4.4 0.3 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KOS12793.1 - 1.5 7.4 5.1 0.91 8.1 0.4 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Mnd1 PF03962.10 KOS12793.1 - 1.9 8.1 5.9 2.6 7.6 0.8 3.0 2 1 1 3 3 3 0 Mnd1 family TBPIP PF07106.8 KOS12793.1 - 2.2 7.8 6.4 0.53 9.8 0.5 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Occludin_ELL PF07303.8 KOS12793.1 - 4.7 8.0 8.5 1.1 10.0 0.1 3.3 3 0 0 3 3 3 0 Occludin homology domain Rer1 PF03248.8 KOS12794.1 - 9.4e-78 259.8 0.5 1.1e-77 259.6 0.3 1.0 1 0 0 1 1 1 1 Rer1 family UCR_hinge PF02320.11 KOS12795.1 - 7e-10 38.7 1.6 1.2e-09 37.9 1.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 KOS12795.1 - 0.0045 16.6 9.3 0.0059 16.2 6.5 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region GDNF PF02351.11 KOS12795.1 - 0.006 17.0 0.4 0.0092 16.4 0.3 1.3 1 0 0 1 1 1 1 GDNF/GAS1 domain PRP1_N PF06424.7 KOS12795.1 - 0.026 14.8 2.5 0.029 14.7 1.8 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2457 PF10446.4 KOS12795.1 - 0.035 12.8 10.5 0.037 12.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BMF PF15185.1 KOS12795.1 - 0.061 12.6 4.7 0.07 12.4 3.3 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Bunya_G2 PF03563.8 KOS12795.1 - 0.062 12.1 0.1 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 TRAP_alpha PF03896.11 KOS12795.1 - 0.074 12.0 4.9 0.067 12.1 3.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prp19_bind PF06991.6 KOS12795.1 - 0.081 12.1 14.0 0.096 11.9 9.7 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Nop14 PF04147.7 KOS12795.1 - 0.1 10.5 9.6 0.11 10.3 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 KOS12795.1 - 0.13 12.1 7.3 0.15 12.0 5.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop53 PF07767.6 KOS12795.1 - 0.15 11.0 5.0 0.16 10.9 3.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myc_N PF01056.13 KOS12795.1 - 0.17 11.0 9.7 0.18 10.9 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 KOS12795.1 - 0.19 11.0 4.6 0.18 11.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_RNA_Pol_19 PF05320.7 KOS12795.1 - 0.22 11.2 6.8 0.27 10.9 4.7 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ANAPC15 PF15243.1 KOS12795.1 - 0.35 10.9 14.6 0.18 11.8 8.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SDA1 PF05285.7 KOS12795.1 - 0.5 9.6 9.9 0.49 9.6 6.9 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KOS12795.1 - 0.52 8.7 14.7 0.51 8.7 10.2 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KOS12795.1 - 0.52 8.2 6.7 0.53 8.2 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 KOS12795.1 - 0.64 10.2 20.2 1 9.6 14.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Retinal PF15449.1 KOS12795.1 - 0.82 7.2 4.7 0.83 7.2 3.3 1.0 1 0 0 1 1 1 0 Retinal protein Paf1 PF03985.8 KOS12795.1 - 1.4 7.5 9.5 1.5 7.4 6.6 1.1 1 0 0 1 1 1 0 Paf1 VID27 PF08553.5 KOS12795.1 - 1.4 7.0 10.1 1.4 7.0 7.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein alpha-hel2 PF14456.1 KOS12795.1 - 1.6 7.4 5.7 1.6 7.3 3.9 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 FAM176 PF14851.1 KOS12795.1 - 1.7 8.2 7.2 2.3 7.8 5.0 1.2 1 0 0 1 1 1 0 FAM176 family Upf2 PF04050.9 KOS12795.1 - 2.4 7.9 14.4 2.7 7.7 10.0 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 BSP_II PF05432.6 KOS12795.1 - 2.5 7.3 17.0 3.2 6.9 11.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 KOS12795.1 - 3.1 8.1 10.8 4.6 7.6 7.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KOS12795.1 - 3.2 7.2 20.3 4.4 6.8 14.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin eIF-3c_N PF05470.7 KOS12795.1 - 4.1 5.3 7.4 4.5 5.2 5.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cwf_Cwc_15 PF04889.7 KOS12795.1 - 4.1 7.0 10.9 5.1 6.7 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KOS12795.1 - 4.1 7.4 12.3 4.7 7.2 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Radial_spoke PF04712.7 KOS12795.1 - 4.7 5.8 13.1 5.4 5.6 9.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Sporozoite_P67 PF05642.6 KOS12795.1 - 5.2 4.8 5.5 5.5 4.7 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 KOS12795.1 - 8 6.2 11.2 11 5.8 7.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3336 PF11815.3 KOS12796.1 - 9.5e-39 132.2 0.8 1.6e-38 131.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KOS12796.1 - 1e-21 77.7 0.0 2.3e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Actin PF00022.14 KOS12797.1 - 3.8e-86 288.9 0.0 5.2e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Actin Robl_LC7 PF03259.12 KOS12797.1 - 0.15 11.6 0.1 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 Roadblock/LC7 domain Ribosomal_L4 PF00573.17 KOS12798.1 - 2.1e-44 151.2 0.8 3.2e-44 150.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KOS12798.1 - 1.8e-27 95.0 1.1 1.8e-27 95.0 0.7 2.8 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain PRMT5 PF05185.11 KOS12799.1 - 1.7e-146 488.7 0.0 2.1e-146 488.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 KOS12799.1 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS12799.1 - 0.0092 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AP_endonuc_2 PF01261.19 KOS12799.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Methyltransf_20 PF12147.3 KOS12799.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KOS12799.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PAPS_reduct PF01507.14 KOS12800.1 - 2.7e-39 134.7 0.0 3.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family LIP PF03583.9 KOS12801.1 - 2.4e-71 240.3 0.1 3.1e-71 239.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS12801.1 - 2.3e-08 33.8 1.1 2.1e-07 30.7 0.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS12801.1 - 2.9e-05 24.0 2.4 0.00039 20.3 1.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS12801.1 - 0.00014 21.1 7.7 0.0054 15.9 0.0 3.1 1 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KOS12801.1 - 0.01 15.3 0.1 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KOS12801.1 - 0.014 14.9 0.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2048 PF09752.4 KOS12801.1 - 0.025 13.4 0.8 0.39 9.5 0.6 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 KOS12801.1 - 0.062 12.9 0.4 4.3 6.9 0.0 2.5 1 1 1 2 2 2 0 Lipase (class 3) DNA_pol_A PF00476.15 KOS12802.1 - 2.6e-87 292.9 0.0 3.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Aconitase PF00330.15 KOS12803.1 - 3.2e-171 569.9 0.1 6.9e-171 568.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS12803.1 - 2.5e-44 150.5 0.0 4.6e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1754 PF08555.5 KOS12804.1 - 2.7e-09 37.5 14.1 4e-08 33.7 9.7 2.0 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Tropomyosin PF00261.15 KOS12804.1 - 0.006 15.6 3.6 0.0072 15.4 2.5 1.0 1 0 0 1 1 1 1 Tropomyosin FH2 PF02181.18 KOS12805.1 - 3.5e-67 226.8 0.8 3.5e-67 226.8 0.5 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KOS12805.1 - 4.2e-44 150.3 0.1 1.9e-43 148.2 0.1 2.2 1 1 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KOS12805.1 - 5.5e-44 149.7 0.0 1.8e-43 148.1 0.0 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain XRN_N PF03159.13 KOS12806.1 - 2e-100 335.0 0.0 3e-100 334.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Redoxin PF08534.5 KOS12807.1 - 1.7e-32 111.9 0.0 1.9e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KOS12807.1 - 4.9e-11 42.4 0.0 6e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HLH PF00010.21 KOS12808.1 - 1.1e-09 37.8 0.0 4e-09 36.0 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 KOS12808.1 - 0.016 14.9 2.4 0.76 9.5 0.6 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FliJ PF02050.11 KOS12808.1 - 0.033 14.2 1.3 0.087 12.8 0.2 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 KOS12808.1 - 0.046 13.4 0.3 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit Sec10 PF07393.6 KOS12809.1 - 1.2e-82 278.2 0.0 1.7e-82 277.7 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KOS12809.1 - 1.2e-10 40.9 0.0 4.2e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS12809.1 - 2e-09 36.8 0.2 4.3e-08 32.6 0.0 2.7 2 0 0 2 2 2 1 F-box domain Rrn6 PF10214.4 KOS12809.1 - 0.015 13.4 0.4 0.027 12.6 0.1 1.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Choline_kinase PF01633.15 KOS12810.1 - 2.5e-36 125.2 0.0 1.3e-34 119.6 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KOS12810.1 - 1.8e-07 31.1 1.3 0.0011 18.7 0.0 3.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family DUF4423 PF14394.1 KOS12810.1 - 0.22 11.0 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DnaJ PF00226.26 KOS12811.1 - 4.2e-08 32.8 0.0 5.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KOS12811.1 - 0.00013 21.8 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Pam16 ChAPs PF09295.5 KOS12812.1 - 7.4e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.12 KOS12812.1 - 0.035 14.0 1.6 0.051 13.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3818 PF12825.2 KOS12813.1 - 1.6e-101 339.4 0.1 2.2e-101 338.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KOS12813.1 - 2.1e-32 111.5 0.2 6.3e-32 110.0 0.1 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KOS12813.1 - 5.1e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 PX domain Ribosomal_L37ae PF01780.14 KOS12814.1 - 2.5e-40 136.2 6.6 2.8e-40 136.0 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KOS12814.1 - 0.0032 17.2 1.5 0.0049 16.6 1.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 KOS12814.1 - 0.029 14.2 0.7 0.034 13.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) OrfB_Zn_ribbon PF07282.6 KOS12814.1 - 0.039 13.6 1.1 0.053 13.1 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain NOB1_Zn_bind PF08772.6 KOS12814.1 - 0.047 13.5 2.7 0.18 11.6 0.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.17 KOS12814.1 - 0.052 13.2 1.3 0.078 12.7 0.9 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.1 KOS12814.1 - 0.052 13.8 0.4 0.46 10.8 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 KOS12814.1 - 0.058 13.1 1.9 3.1 7.6 0.0 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C4_ClpX PF06689.8 KOS12814.1 - 0.065 12.7 1.6 0.072 12.6 0.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger GCC2_GCC3 PF07699.8 KOS12814.1 - 0.068 12.7 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 zf-ribbon_3 PF13248.1 KOS12814.1 - 0.082 12.1 0.5 3.9 6.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 KOS12814.1 - 0.091 12.2 2.5 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.9 KOS12814.1 - 0.12 12.0 1.1 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Sec23_Sec24 PF04810.10 KOS12814.1 - 0.14 11.7 0.6 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 KOS12814.1 - 0.66 9.9 2.8 1.4 8.9 0.1 2.4 3 0 0 3 3 3 0 Zinc ribbon domain Ribosomal_L44 PF00935.14 KOS12814.1 - 2.2 8.3 6.0 1.3 9.0 0.9 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Sugar_tr PF00083.19 KOS12815.1 - 2.8e-98 329.4 20.6 3.6e-98 329.0 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS12815.1 - 3.5e-16 58.8 7.8 3.5e-16 58.8 5.4 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Ras PF00071.17 KOS12816.1 - 5.6e-47 159.1 0.0 6.8e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS12816.1 - 9.8e-17 61.5 0.1 1.4e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS12816.1 - 2.2e-11 43.3 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS12816.1 - 2.1e-06 27.0 0.0 2.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS12816.1 - 0.00098 19.0 0.1 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sigma54_activat PF00158.21 KOS12816.1 - 0.0072 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KOS12816.1 - 0.013 15.6 0.2 0.032 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KOS12816.1 - 0.014 15.3 0.1 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KOS12816.1 - 0.062 12.7 0.1 0.74 9.2 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KOS12816.1 - 0.11 12.0 0.0 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 KOS12817.1 - 9e-36 120.4 2.7 1.3e-08 34.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Lactamase_B_2 PF12706.2 KOS12818.1 - 3.1e-17 62.7 0.0 7.7e-17 61.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS12818.1 - 0.00031 20.4 2.6 0.00042 20.0 1.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Sulfotransfer_1 PF00685.22 KOS12818.1 - 0.099 11.8 0.1 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase domain PDEase_II PF02112.10 KOS12818.1 - 0.15 10.9 0.2 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PAP2 PF01569.16 KOS12819.1 - 4e-10 39.4 8.6 4e-10 39.4 6.0 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KOS12819.1 - 1e-05 25.1 10.5 5.2e-05 22.8 7.3 2.1 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KOS12819.1 - 5.1 7.4 16.8 0.028 14.6 4.4 2.6 2 1 2 4 4 4 0 PAP2 superfamily C-terminal SET PF00856.23 KOS12820.1 - 9.9e-25 87.7 0.3 5.6e-24 85.2 0.0 2.4 2 1 0 2 2 2 1 SET domain N-SET PF11764.3 KOS12820.1 - 1.5e-10 41.1 1.5 1.5e-10 41.1 1.0 2.8 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N RRM_6 PF14259.1 KOS12820.1 - 0.0004 20.2 0.0 0.0018 18.1 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS12820.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 KOS12820.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF1875 PF08961.5 KOS12820.1 - 0.66 9.2 4.0 0.28 10.4 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) Robl_LC7 PF03259.12 KOS12822.1 - 6.5e-06 25.6 0.0 7.4e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain UPF0203 PF05254.7 KOS12823.1 - 0.00036 20.3 1.8 0.0011 18.8 1.3 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 KOS12823.1 - 0.0011 18.8 4.1 0.0017 18.1 2.7 1.4 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KOS12823.1 - 0.0058 16.3 5.3 0.03 14.0 1.5 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KOS12823.1 - 0.0069 16.3 2.7 0.35 10.9 2.1 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) DUF3551 PF12071.3 KOS12823.1 - 0.04 13.4 1.9 0.042 13.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) COX6B PF02297.12 KOS12823.1 - 0.14 12.1 3.5 0.3 11.1 2.4 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.8 KOS12823.1 - 0.14 11.5 2.7 0.79 9.1 0.1 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.11 KOS12823.1 - 0.23 11.4 1.4 0.3 11.0 1.0 1.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.4 KOS12823.1 - 0.25 11.4 2.4 0.38 10.8 1.7 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 WD40 PF00400.27 KOS12824.1 - 3.2e-45 150.4 18.1 2.2e-10 40.0 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS12824.1 - 0.00028 20.4 2.9 0.13 11.7 0.1 3.2 1 1 2 3 3 3 3 PQQ-like domain Nup160 PF11715.3 KOS12824.1 - 0.00044 18.5 1.9 0.012 13.8 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KOS12824.1 - 0.0006 19.9 9.6 0.28 11.4 0.2 5.4 5 1 1 6 6 6 1 PQQ-like domain Kelch_2 PF07646.10 KOS12824.1 - 0.047 13.4 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Kelch motif IKI3 PF04762.7 KOS12824.1 - 0.3 8.8 0.0 1.6 6.4 0.0 1.8 1 1 1 2 2 2 0 IKI3 family WD40 PF00400.27 KOS12825.1 - 1.5e-06 27.8 0.2 0.00022 20.9 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS12825.1 - 0.01 15.3 0.0 0.039 13.4 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain CNH PF00780.17 KOS12825.1 - 0.039 13.3 0.0 1.1 8.5 0.0 2.7 3 0 0 3 3 3 0 CNH domain 2OG-FeII_Oxy PF03171.15 KOS12826.1 - 1.5e-17 63.6 0.0 2.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sld5 PF05916.6 KOS12827.1 - 0.00011 22.4 0.1 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 GINS complex protein NIF PF03031.13 KOS12828.1 - 7e-08 32.2 0.3 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF2036 PF09724.4 KOS12829.1 - 4.1e-50 170.7 0.0 5e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) ORC4_C PF14629.1 KOS12829.1 - 0.043 13.2 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus SBF PF01758.11 KOS12830.1 - 1.1e-46 158.6 12.3 1.1e-46 158.6 8.5 2.7 3 0 0 3 3 3 1 Sodium Bile acid symporter family RF-1 PF00472.15 KOS12831.1 - 8.5e-16 57.7 1.9 1.3e-15 57.1 1.3 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KOS12831.1 - 0.021 14.9 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein DUF1843 PF08898.5 KOS12831.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) YgaB PF14182.1 KOS12831.1 - 0.28 11.4 3.2 0.52 10.5 2.2 1.4 1 0 0 1 1 1 0 YgaB-like protein OmpH PF03938.9 KOS12831.1 - 2.5 8.0 8.4 3.3 7.6 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exo_endo_phos PF03372.18 KOS12832.1 - 5.2e-16 59.3 0.1 7.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KOS12832.1 - 6.9e-11 41.8 0.0 2.3e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KOS12832.1 - 4.2e-06 26.5 4.9 4.8e-05 23.1 3.4 2.3 1 1 0 1 1 1 1 GRF zinc finger DUF1214 PF06742.6 KOS12833.1 - 1e-12 48.4 0.8 2.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) MIT PF04212.13 KOS12833.1 - 0.0051 16.6 0.2 0.009 15.8 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain CBM_X PF06204.6 KOS12833.1 - 0.013 15.0 0.1 0.059 12.8 0.1 2.2 1 0 0 1 1 1 0 Putative carbohydrate binding domain DUF2404 PF10296.4 KOS12834.1 - 0.00031 20.8 0.0 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Na_Ca_ex PF01699.19 KOS12835.1 - 2.4e-25 88.7 23.5 2.8e-19 69.0 6.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DnaJ PF00226.26 KOS12836.1 - 2.5e-20 71.9 0.1 3.5e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KOS12836.1 - 1.5e-11 43.5 0.1 2.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 KOS12836.1 - 0.0016 17.9 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KOS12836.1 - 0.0027 17.3 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain GPI-anchored PF10342.4 KOS12837.1 - 5.8e-06 26.7 0.0 8.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Thi4 PF01946.12 KOS12838.1 - 8e-88 293.3 0.1 1e-87 293.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KOS12838.1 - 6e-09 35.2 0.9 1.5e-08 33.9 0.7 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS12838.1 - 6.1e-08 32.5 0.1 1.7e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KOS12838.1 - 1.9e-06 27.0 0.1 2.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KOS12838.1 - 6.1e-06 25.3 1.8 1.5e-05 24.0 0.9 1.8 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS12838.1 - 7.2e-06 26.0 0.3 1.7e-05 24.8 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS12838.1 - 4.6e-05 23.2 0.2 0.0003 20.5 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KOS12838.1 - 0.00019 20.0 0.4 0.0003 19.3 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KOS12838.1 - 0.00083 19.4 1.0 0.0028 17.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS12838.1 - 0.0019 17.1 0.1 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KOS12838.1 - 0.014 14.4 0.2 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KOS12838.1 - 0.037 13.7 1.4 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KOS12838.1 - 0.039 12.5 0.2 0.056 12.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 KOS12838.1 - 0.04 13.0 0.1 0.59 9.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase CAP_GLY PF01302.20 KOS12840.1 - 5.3e-22 77.2 1.6 8.1e-22 76.7 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KOS12840.1 - 1.3e-11 44.5 0.0 3.2e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Pkinase PF00069.20 KOS12841.1 - 9.9e-62 208.4 0.0 1.2e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12841.1 - 1.5e-35 122.5 0.0 2.2e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12841.1 - 1.5e-05 24.1 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KOS12841.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KOS12841.1 - 0.042 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KOS12841.1 - 0.088 12.1 0.4 0.22 10.8 0.0 1.9 3 0 0 3 3 3 0 RIO1 family COPIIcoated_ERV PF07970.7 KOS12842.1 - 2.6e-64 216.8 0.0 3.7e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KOS12842.1 - 7.8e-31 105.9 0.0 1.7e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3437 PF11919.3 KOS12843.1 - 1.1e-28 98.7 0.1 7.3e-28 96.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KOS12843.1 - 1.2e-06 28.0 3.7 0.0034 17.3 0.1 6.2 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KOS12843.1 - 0.00015 21.9 0.1 0.00015 21.9 0.0 4.9 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.18 KOS12843.1 - 0.17 11.7 5.0 0.5 10.2 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Tubulin PF00091.20 KOS12844.1 - 1.1e-69 234.5 0.0 1.5e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS12844.1 - 3.3e-47 159.6 0.0 5.1e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KOS12844.1 - 0.00061 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KOS12844.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Transaldolase PF00923.14 KOS12845.1 - 5.6e-94 314.4 0.0 6.3e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DUF1845 PF08900.6 KOS12845.1 - 0.15 11.2 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) Cse1 PF08506.5 KOS12846.1 - 2.3e-131 437.7 0.3 4.6e-131 436.7 0.2 1.5 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 KOS12846.1 - 4.6e-123 410.7 0.2 9.8e-123 409.6 0.1 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 KOS12846.1 - 3.8e-14 52.3 1.7 4.8e-12 45.6 0.2 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KOS12846.1 - 3.7e-05 23.6 0.9 0.0075 16.1 0.1 4.9 6 1 0 6 6 6 1 Exportin 1-like protein 2-oxoacid_dh PF00198.18 KOS12847.1 - 1.1e-78 263.6 0.1 1.6e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KOS12847.1 - 4e-20 71.2 2.2 7.5e-20 70.3 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 KOS12847.1 - 0.002 18.4 0.1 1.3 9.3 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KOS12847.1 - 0.014 15.0 0.2 0.31 10.7 0.1 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF1510 PF07423.6 KOS12847.1 - 0.33 10.2 25.7 0.55 9.5 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 KOS12847.1 - 2.8 6.3 43.4 3.7 5.9 30.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDE_Tnp_1_2 PF13586.1 KOS12847.1 - 3 8.0 4.8 7.5 6.8 3.2 1.9 1 1 0 1 1 1 0 Transposase DDE domain Ndc1_Nup PF09531.5 KOS12847.1 - 4.3 5.6 12.2 5.7 5.2 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 KOS12847.1 - 4.8 6.2 12.8 7.5 5.6 8.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain MSA_2 PF00985.12 KOS12847.1 - 5.8 7.0 12.8 9.4 6.3 8.9 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family CDC45 PF02724.9 KOS12847.1 - 7.7 4.4 19.8 11 3.9 13.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hydantoinase_B PF02538.9 KOS12848.1 - 9.7e-186 618.0 0.0 2.1e-185 616.9 0.0 1.4 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Motile_Sperm PF00635.21 KOS12850.1 - 6.6e-28 96.5 0.1 1.3e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 KOS12850.1 - 0.059 13.4 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase MAS20 PF02064.10 KOS12851.1 - 5.4e-20 71.5 6.9 8.2e-20 70.9 1.7 2.8 2 1 0 2 2 2 1 MAS20 protein import receptor DUF2201_N PF13203.1 KOS12851.1 - 0.36 9.9 9.6 0.037 13.1 2.6 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain GOLD_2 PF13897.1 KOS12851.1 - 1.2 9.3 6.9 1.4 9.1 0.0 2.5 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking HK97-gp10_like PF04883.7 KOS12851.1 - 5 8.1 9.0 1.2 10.1 1.1 2.4 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component NESP55 PF06390.7 KOS12851.1 - 5.8 6.2 14.6 0.88 8.8 7.5 1.5 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Plasmodium_Vir PF05795.6 KOS12851.1 - 6.4 5.8 7.4 27 3.8 2.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein 60KD_IMP PF02096.15 KOS12852.1 - 1.9e-14 53.8 0.1 2.7e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Uds1 PF15456.1 KOS12853.1 - 5.3e-11 42.5 4.1 5.3e-11 42.5 2.8 6.2 4 2 1 5 5 5 1 Up-regulated During Septation Baculo_PEP_C PF04513.7 KOS12853.1 - 9.9 5.9 12.1 11 5.8 0.4 4.5 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyclin PF08613.6 KOS12854.1 - 1.7e-10 41.4 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Adaptin_binding PF10199.4 KOS12855.1 - 6.7e-06 26.4 0.0 1.8e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Glyco_hydro_43 PF04616.9 KOS12856.1 - 1.8e-37 128.9 0.1 2.1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HSP70 PF00012.15 KOS12857.1 - 3.6e-260 864.0 15.9 4.1e-260 863.8 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS12857.1 - 4.9e-16 58.2 6.0 3.8e-14 52.0 2.7 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KOS12857.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KOS12857.1 - 0.019 14.8 11.6 0.52 10.1 0.8 4.1 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 KOS12857.1 - 0.078 12.0 0.1 0.078 12.0 0.1 3.5 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Seryl_tRNA_N PF02403.17 KOS12857.1 - 0.87 9.6 8.9 3 7.9 6.1 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-Apc11 PF12861.2 KOS12858.1 - 2.1e-28 98.0 10.3 2.4e-28 97.7 7.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KOS12858.1 - 3e-25 88.0 10.1 3.6e-25 87.8 7.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KOS12858.1 - 1.5e-07 31.0 14.5 1.1e-06 28.3 10.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS12858.1 - 6.4e-06 25.7 9.1 1.5e-05 24.5 6.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS12858.1 - 0.00027 20.8 8.8 0.0032 17.4 6.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS12858.1 - 0.00086 18.9 8.8 0.0081 15.8 5.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS12858.1 - 0.0049 16.7 8.7 0.008 16.0 2.5 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KOS12858.1 - 0.028 14.0 10.7 0.2 11.3 7.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KOS12858.1 - 0.034 14.1 6.8 0.034 14.1 4.7 1.9 2 1 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 KOS12858.1 - 0.041 13.4 2.2 0.041 13.4 1.5 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KOS12858.1 - 0.065 13.2 12.6 0.52 10.3 8.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 KOS12858.1 - 0.24 11.5 6.9 0.59 10.3 4.9 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KOS12858.1 - 0.25 11.3 6.1 0.077 13.0 2.5 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.2 KOS12858.1 - 0.57 10.2 10.4 0.18 11.8 4.6 2.1 2 1 0 2 2 2 0 RING-variant domain zf-Nse PF11789.3 KOS12858.1 - 0.62 9.6 5.9 1 8.9 4.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 KOS12858.1 - 5 6.6 9.2 5.9 6.4 0.3 3.3 3 1 1 4 4 4 0 RecR protein DAO PF01266.19 KOS12859.1 - 2.4e-47 161.5 0.3 7.2e-47 160.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS12859.1 - 3.2e-09 36.1 0.9 1.9e-05 23.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KOS12859.1 - 4.5e-07 29.2 0.2 9.7e-07 28.2 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS12859.1 - 5.7e-05 23.0 0.4 0.00026 20.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS12859.1 - 0.00038 20.4 0.6 0.0013 18.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KOS12859.1 - 0.0037 16.1 0.1 0.039 12.8 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KOS12859.1 - 0.0042 15.6 1.1 0.0068 14.9 0.8 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KOS12859.1 - 0.0043 16.1 0.1 0.008 15.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KOS12859.1 - 0.013 15.8 0.5 0.031 14.6 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KOS12859.1 - 0.02 14.5 0.2 0.048 13.2 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KOS12859.1 - 0.041 13.9 0.1 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS12859.1 - 0.078 12.0 0.1 0.31 10.0 0.1 1.9 3 0 0 3 3 3 0 FAD binding domain BCAS2 PF05700.6 KOS12860.1 - 7.8e-49 166.1 8.8 1e-48 165.7 6.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) IncA PF04156.9 KOS12860.1 - 2.5 7.6 9.0 3 7.3 1.4 2.2 2 0 0 2 2 2 0 IncA protein G6PD_C PF02781.11 KOS12861.1 - 1.6e-112 375.1 0.0 2.2e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KOS12861.1 - 2.3e-59 200.7 0.0 3.7e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KOS12861.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_2 PF08442.5 KOS12862.1 - 7.1e-72 241.0 0.2 1.3e-71 240.2 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KOS12862.1 - 6.3e-23 81.0 1.8 1.3e-22 80.0 1.0 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 KOS12862.1 - 7.1e-13 48.2 0.3 1.5e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KOS12862.1 - 3.6e-05 23.5 0.0 5.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KOS12862.1 - 0.0022 17.6 0.6 0.0056 16.2 0.0 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KOS12862.1 - 0.0086 15.5 0.0 0.12 11.7 0.0 2.3 1 1 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 KOS12862.1 - 0.018 14.3 0.2 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 KOS12862.1 - 0.049 12.9 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain Ebp2 PF05890.7 KOS12863.1 - 1.8e-80 270.1 25.2 1.8e-80 270.1 17.5 3.2 3 1 0 3 3 3 1 Eukaryotic rRNA processing protein EBP2 E1-E2_ATPase PF00122.15 KOS12864.1 - 3.2e-22 78.7 0.0 6.6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KOS12864.1 - 7.4e-21 75.1 0.0 1.5e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS12864.1 - 3e-20 73.5 0.0 7.3e-19 69.0 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS12864.1 - 0.0028 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KOS12864.1 - 0.01 15.4 0.1 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L19e PF01280.15 KOS12865.1 - 2.9e-62 208.8 11.7 2.9e-62 208.8 8.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e TFIIS_M PF07500.9 KOS12865.1 - 0.25 11.4 6.4 0.096 12.7 2.8 1.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain ATP-synt_ab PF00006.20 KOS12866.1 - 1.4e-61 207.7 0.0 1.9e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS12866.1 - 5e-19 68.8 0.1 1e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS12866.1 - 5.7e-11 42.4 0.2 1.2e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KOS12866.1 - 0.00031 20.5 0.1 0.00075 19.3 0.1 1.7 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 KOS12866.1 - 0.096 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DUF3533 PF12051.3 KOS12866.1 - 0.13 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFIIS_C PF01096.13 KOS12867.1 - 3.6e-16 58.4 0.5 3.6e-16 58.4 0.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KOS12867.1 - 4.8e-06 26.1 7.2 0.0037 16.9 0.1 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 KOS12867.1 - 5.8e-05 22.8 6.3 0.047 13.5 0.1 3.0 2 1 0 2 2 2 2 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 KOS12867.1 - 0.00015 21.3 4.9 0.018 14.6 0.1 2.6 2 1 0 2 2 2 1 Putative transposase DNA-binding domain HypA PF01155.14 KOS12867.1 - 0.00078 19.1 2.3 0.43 10.2 0.0 2.6 2 1 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF2387 PF09526.5 KOS12867.1 - 0.0019 18.1 0.7 1.6 8.7 0.2 2.4 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) Terminase_GpA PF05876.7 KOS12867.1 - 0.0039 15.6 0.7 0.0054 15.1 0.2 1.3 1 1 0 2 2 2 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 KOS12867.1 - 0.0044 17.2 0.7 0.0044 17.2 0.5 2.6 2 1 0 2 2 2 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 KOS12867.1 - 0.0053 16.0 11.3 0.29 10.4 1.5 3.5 2 2 1 3 3 3 2 TFIIB zinc-binding Prok-RING_1 PF14446.1 KOS12867.1 - 0.0067 16.1 9.3 0.063 13.0 0.6 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 DNA_RNApol_7kD PF03604.8 KOS12867.1 - 0.017 14.5 0.3 0.017 14.5 0.2 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 KOS12867.1 - 0.018 14.9 3.6 2 8.4 0.1 3.3 3 0 0 3 3 3 0 zinc-finger DUF1451 PF07295.6 KOS12867.1 - 0.02 14.6 2.8 0.39 10.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) zf-DNA_Pol PF08996.5 KOS12867.1 - 0.044 13.1 0.9 0.079 12.3 0.3 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-TFIIB PF13453.1 KOS12867.1 - 0.052 12.7 1.5 0.052 12.7 1.0 2.3 3 1 0 3 3 3 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.5 KOS12867.1 - 0.074 13.0 15.5 4 7.4 1.2 3.8 2 2 1 4 4 4 0 Zinc ribbon domain CpXC PF14353.1 KOS12867.1 - 0.082 12.8 6.3 5.7 6.9 0.0 3.3 3 1 1 4 4 3 0 CpXC protein zinc_ribbon_5 PF13719.1 KOS12867.1 - 0.12 11.9 8.8 6.8 6.3 0.4 4.0 3 1 1 4 4 4 0 zinc-ribbon domain IBR PF01485.16 KOS12867.1 - 0.12 12.2 3.9 7.6 6.4 1.0 2.7 2 1 0 2 2 2 0 IBR domain zf-ribbon_3 PF13248.1 KOS12867.1 - 0.17 11.1 16.6 1.6 8.0 0.3 3.7 3 1 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 KOS12867.1 - 0.19 11.1 0.2 0.19 11.1 0.1 2.6 3 1 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.1 KOS12867.1 - 0.21 11.3 9.4 8.8 6.1 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain zf-ISL3 PF14690.1 KOS12867.1 - 0.22 11.5 6.6 20 5.3 0.2 3.8 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 A2L_zn_ribbon PF08792.5 KOS12867.1 - 0.24 10.8 9.2 0.45 10.0 0.2 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Nudix_N_2 PF14803.1 KOS12867.1 - 0.25 11.0 11.1 7.6 6.3 2.9 4.0 3 1 1 4 4 4 0 Nudix N-terminal Ribosomal_S27e PF01667.12 KOS12867.1 - 0.28 10.7 8.8 1.3 8.5 0.0 4.1 4 1 1 5 5 4 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.1 KOS12867.1 - 0.37 10.3 0.3 0.37 10.3 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Nop10p PF04135.7 KOS12867.1 - 0.64 9.8 2.8 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family Zn_Tnp_IS1595 PF12760.2 KOS12867.1 - 2.8 7.8 11.0 4.4 7.2 1.9 3.7 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.1 KOS12867.1 - 4 7.2 5.9 17 5.2 0.3 3.0 3 0 0 3 3 3 0 zinc-RING finger domain zf-NADH-PPase PF09297.6 KOS12867.1 - 4.1 6.9 14.8 19 4.8 0.1 3.8 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.8 KOS12867.1 - 5.1 6.6 12.9 1.1 8.8 0.4 3.2 2 2 1 3 3 3 0 CSL zinc finger Zn_ribbon_recom PF13408.1 KOS12867.1 - 5.8 7.2 7.5 25 5.2 0.1 3.3 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 KOS12867.1 - 6.2 6.9 8.5 13 5.8 2.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain GFA PF04828.9 KOS12867.1 - 6.3 6.8 7.5 33 4.5 0.6 3.2 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF678 PF05077.7 KOS12867.1 - 6.8 6.7 11.6 0.89 9.5 0.3 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF678) DUF2082 PF09855.4 KOS12867.1 - 6.9 6.5 9.8 19 5.1 0.0 3.4 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-AN1 PF01428.11 KOS12867.1 - 8.3 6.3 7.2 25 4.8 0.1 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger TraC_F_IV PF11130.3 KOS12868.1 - 0.032 13.6 1.5 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Syntaxin-18_N PF10496.4 KOS12868.1 - 0.062 13.1 0.9 1.9 8.4 0.1 3.0 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus bZIP_1 PF00170.16 KOS12868.1 - 0.35 10.8 9.5 0.17 11.8 0.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor AA_kinase PF00696.23 KOS12869.1 - 1.3e-37 129.6 0.0 4.6e-37 127.8 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KOS12869.1 - 4.8e-09 35.4 0.5 8.3e-05 21.9 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KOS12869.1 - 3e-08 33.0 1.8 1.2e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 ACT domain Complex1_49kDa PF00346.14 KOS12870.1 - 6.4e-122 405.7 0.0 8.7e-122 405.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ribosomal_S26e PF01283.14 KOS12871.1 - 1.4e-52 176.6 6.6 1.7e-52 176.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e ACOX PF01756.14 KOS12872.1 - 2.6e-46 157.3 0.0 5.4e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 KOS12872.1 - 5.6e-15 54.5 0.5 1.6e-14 53.1 0.3 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KOS12872.1 - 3e-08 33.8 0.1 1.1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KOS12872.1 - 4e-06 27.1 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal NMT1 PF09084.6 KOS12873.1 - 5.1e-74 248.5 0.0 6.4e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KOS12873.1 - 6.1e-06 25.8 0.2 0.00036 20.0 0.1 2.5 1 1 0 1 1 1 1 NMT1-like family PBP_like PF12727.2 KOS12873.1 - 0.026 13.4 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 PBP superfamily domain Phosphonate-bd PF12974.2 KOS12873.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein zf-PARP PF00645.13 KOS12874.1 - 0.0016 18.6 0.1 0.0039 17.3 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AvrE PF11725.3 KOS12874.1 - 2.1 5.2 11.8 2.3 5.1 8.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor Spo7 PF03907.8 KOS12875.1 - 2.8e-07 30.3 0.1 3.1e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.4 KOS12875.1 - 0.0024 17.8 0.1 0.0028 17.6 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 188 7tm_1 PF00001.16 KOS12875.1 - 0.026 13.6 0.1 0.028 13.5 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.4 KOS12875.1 - 0.032 13.0 1.1 0.036 12.8 0.4 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt DUF2838 PF10998.3 KOS12875.1 - 0.033 14.0 0.2 0.043 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) Zwint PF15556.1 KOS12875.1 - 0.047 12.9 0.1 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 ZW10 interactor DUF1356 PF07092.7 KOS12875.1 - 0.11 11.7 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) XPG_I_2 PF12813.2 KOS12876.1 - 2.4e-05 23.9 0.3 0.00011 21.8 0.0 2.2 2 1 1 3 3 3 1 XPG domain containing Nro1 PF12753.2 KOS12876.1 - 0.0062 15.5 1.7 0.0062 15.5 1.2 1.8 2 0 0 2 2 2 1 Nuclear pore complex subunit Nro1 XPG_N PF00752.12 KOS12876.1 - 0.025 14.8 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain TRAP_alpha PF03896.11 KOS12876.1 - 0.2 10.6 7.2 0.39 9.6 5.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRP7 PF12923.2 KOS12876.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) Nop14 PF04147.7 KOS12876.1 - 0.63 7.8 8.5 0.91 7.3 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 KOS12876.1 - 3.9 5.5 5.4 5.8 5.0 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein IF4E PF01652.13 KOS12877.1 - 4.8e-47 159.5 0.0 7.5e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BIR PF00653.16 KOS12878.1 - 9.9e-21 73.9 0.6 2.5e-20 72.6 0.4 1.7 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain RPN7 PF10602.4 KOS12879.1 - 2.7e-15 56.2 0.0 3.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.1 KOS12879.1 - 0.00062 19.6 0.5 0.0043 16.9 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS12879.1 - 0.0013 18.3 0.1 0.0046 16.6 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS12879.1 - 0.0046 16.5 0.1 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KOS12879.1 - 0.018 14.9 0.1 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KOS12879.1 - 0.02 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS12879.1 - 0.04 14.5 0.1 12 6.8 0.0 3.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS12879.1 - 0.045 13.3 0.3 0.14 11.8 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Viral_protease PF08715.5 KOS12879.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Papain like viral protease SPX PF03105.14 KOS12880.1 - 0.45 10.2 9.7 0.58 9.8 6.7 1.3 1 0 0 1 1 1 0 SPX domain Ly49 PF08391.5 KOS12880.1 - 0.84 9.7 8.1 0.16 12.0 2.0 2.2 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region RWD PF05773.17 KOS12881.1 - 2.1e-19 69.4 2.2 4.2e-19 68.4 1.5 1.5 1 0 0 1 1 1 1 RWD domain DUF106 PF01956.11 KOS12881.1 - 0.31 10.5 2.1 0.5 9.8 1.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DNA_ligase_A_M PF01068.16 KOS12883.1 - 4e-10 39.3 0.0 5.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain ubiquitin PF00240.18 KOS12884.1 - 8.2e-20 69.9 0.1 1.2e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS12884.1 - 1e-09 37.9 0.1 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 KOS12884.1 - 8.6e-07 28.6 0.8 3.1e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 KOS12884.1 - 0.00022 21.3 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KOS12884.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KOS12884.1 - 0.017 15.4 0.2 0.072 13.3 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain SUR7 PF06687.7 KOS12885.1 - 5.1e-16 58.8 6.7 6.6e-16 58.5 4.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 KOS12885.1 - 0.078 11.5 1.2 0.11 11.0 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2614 PF11023.3 KOS12885.1 - 0.56 10.0 6.6 0.22 11.3 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) DUF973 PF06157.6 KOS12885.1 - 0.92 8.4 7.0 0.076 11.9 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF973) SLX9 PF15341.1 KOS12886.1 - 2.6e-11 44.0 8.7 3.3e-11 43.6 6.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 FAM212 PF15342.1 KOS12886.1 - 0.084 12.4 0.0 0.25 10.9 0.0 1.9 1 0 0 1 1 1 0 FAM212 family UbiA PF01040.13 KOS12887.1 - 2.7e-33 115.2 19.6 4e-33 114.7 13.6 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family ADH_zinc_N PF00107.21 KOS12888.1 - 8.9e-31 106.1 0.1 1.7e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS12888.1 - 4.1e-12 45.8 0.1 1.3e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KOS12888.1 - 1.4e-09 38.8 0.1 5.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PALP PF00291.20 KOS12888.1 - 0.011 15.0 0.3 0.016 14.4 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GNAT_acetyltr_2 PF13718.1 KOS12889.1 - 5e-77 257.6 0.0 7.8e-77 257.0 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KOS12889.1 - 1.3e-65 220.3 0.0 7.7e-65 217.8 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KOS12889.1 - 1.3e-34 117.7 0.0 3e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KOS12889.1 - 5.2e-27 93.9 0.8 1.8e-26 92.1 0.6 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 KOS12889.1 - 0.00057 19.8 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS12889.1 - 0.0017 18.4 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_22 PF13401.1 KOS12889.1 - 0.01 15.9 0.4 0.61 10.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain zf-U1 PF06220.7 KOS12890.1 - 8.5e-07 28.4 1.9 1.8e-06 27.3 1.3 1.6 1 0 0 1 1 1 1 U1 zinc finger NeA_P2 PF12312.3 KOS12890.1 - 0.046 12.9 0.4 0.077 12.2 0.1 1.6 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein WD40 PF00400.27 KOS12891.1 - 9.5e-42 139.4 26.0 4.9e-09 35.7 0.0 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat Hira PF07569.6 KOS12891.1 - 2.3e-16 59.6 0.0 1e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 KOS12891.1 - 0.0032 16.9 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 HIRA B motif MYCBPAP PF14646.1 KOS12891.1 - 0.012 14.3 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family CRCB PF02537.10 KOS12892.1 - 1.5e-29 102.2 15.7 5.7e-17 61.6 1.6 2.8 2 1 0 2 2 2 2 CrcB-like protein WD40 PF00400.27 KOS12893.1 - 1.1e-14 53.5 16.5 0.0002 21.1 0.3 7.3 6 3 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS12893.1 - 0.00053 18.8 0.1 0.13 10.9 0.0 3.2 3 1 1 4 4 4 2 Nup133 N terminal like MFS_1 PF07690.11 KOS12894.1 - 3.9e-27 94.8 28.0 6.6e-27 94.1 18.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KOS12894.1 - 0.00038 20.4 1.4 0.0018 18.2 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) ZYG-11_interact PF05884.7 KOS12894.1 - 0.26 10.3 5.8 0.034 13.2 0.9 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 NfeD PF01957.13 KOS12894.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.6 3 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding Phosphoesterase PF04185.9 KOS12895.1 - 3.1e-75 253.7 3.8 5.8e-75 252.8 2.6 1.4 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.9 KOS12896.1 - 8.1e-75 252.3 6.0 1.2e-74 251.8 4.2 1.2 1 0 0 1 1 1 1 Phosphoesterase family EST1_DNA_bind PF10373.4 KOS12897.1 - 2.8e-26 92.3 0.0 9.3e-26 90.6 0.0 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KOS12897.1 - 1.2e-12 47.9 0.1 2.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 Cytochrom_B562 PF07361.6 KOS12897.1 - 0.03 14.7 0.1 0.03 14.7 0.1 2.7 4 0 0 4 4 4 0 Cytochrome b562 RNA_lig_T4_1 PF09511.5 KOS12898.1 - 7.7e-71 238.0 0.0 1.4e-70 237.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KOS12898.1 - 3.4e-32 111.6 0.0 1e-30 106.8 0.0 2.4 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 KOS12898.1 - 1e-14 54.3 0.0 2.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain DUF3608 PF12257.3 KOS12899.1 - 6.2e-68 228.7 0.0 2.5e-67 226.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KOS12899.1 - 4.6e-20 71.1 0.2 9.6e-20 70.1 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PCI PF01399.22 KOS12901.1 - 0.00092 19.5 0.3 0.0059 16.8 0.0 2.3 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.4 KOS12901.1 - 0.0057 16.0 3.5 0.013 14.8 1.4 2.3 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_2 PF07719.12 KOS12901.1 - 5.4 7.1 11.7 25 5.1 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KOS12902.1 - 1.3e-65 221.1 0.0 1.9e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12902.1 - 3.7e-45 154.0 0.0 6.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KOS12902.1 - 3.5e-18 65.4 0.0 6.7e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KOS12902.1 - 5e-12 45.8 0.1 9.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KOS12902.1 - 4.4e-11 42.4 0.0 1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KOS12902.1 - 1.3e-05 24.3 0.0 0.00014 20.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RA PF00788.18 KOS12902.1 - 0.0036 17.7 0.0 0.0082 16.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ribosomal_S27e PF01667.12 KOS12903.1 - 6.4e-28 96.0 3.0 9.1e-28 95.5 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.4 KOS12903.1 - 0.0022 16.9 0.8 0.072 12.1 0.0 2.1 1 1 1 2 2 2 1 Mu-like prophage protein Com zf-CSL PF05207.8 KOS12903.1 - 0.039 13.4 1.2 0.07 12.6 0.8 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF3133 PF11331.3 KOS12903.1 - 0.32 10.6 7.2 0.76 9.3 2.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3133) zinc_ribbon_4 PF13717.1 KOS12903.1 - 0.36 10.5 2.7 5.3 6.8 1.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KOS12903.1 - 0.51 9.9 3.0 6.6 6.4 1.5 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 KOS12903.1 - 3.3 7.2 6.3 1.1 8.7 1.4 2.3 2 1 1 3 3 3 0 InsA N-terminal domain Longin PF13774.1 KOS12904.1 - 1.5e-14 53.2 0.0 2.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KOS12904.1 - 1.4e-13 50.2 1.1 1.4e-13 50.2 0.8 1.6 2 0 0 2 2 2 1 Synaptobrevin Herpes_teg_N PF04843.7 KOS12904.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region COPIIcoated_ERV PF07970.7 KOS12904.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter Pkinase PF00069.20 KOS12905.1 - 3.2e-66 223.1 0.0 3.9e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12905.1 - 1.6e-33 115.8 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12905.1 - 9.2e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS12905.1 - 0.00011 21.9 1.1 0.17 11.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family CAP_N PF01213.14 KOS12905.1 - 9.6 5.3 6.1 15 4.7 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_M22 PF00814.20 KOS12906.1 - 3e-72 243.3 0.1 3.5e-72 243.1 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Complex1_30kDa PF00329.14 KOS12907.1 - 1.2e-35 121.8 0.0 1.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Flg_bbr_C PF06429.8 KOS12907.1 - 0.0075 16.1 0.1 0.38 10.7 0.0 2.3 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal UPF0061 PF02696.9 KOS12908.1 - 1.4e-90 304.0 0.0 1.8e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family N2227 PF07942.7 KOS12909.1 - 6.7e-88 294.1 0.0 9.5e-88 293.6 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KOS12909.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain zf-H2C2_2 PF13465.1 KOS12910.1 - 5.1e-10 39.1 17.5 1.8e-06 27.9 3.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KOS12910.1 - 8.1e-09 35.3 13.3 0.00016 21.8 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS12910.1 - 1.4e-05 25.0 12.5 0.0061 16.8 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KOS12910.1 - 0.26 11.4 3.6 0.43 10.7 2.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KOS12910.1 - 3.6 7.8 7.2 13 6.0 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LCAT PF02450.10 KOS12911.1 - 3.1e-80 270.0 0.1 4e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KOS12911.1 - 0.0024 17.6 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS12911.1 - 0.004 17.0 0.2 0.014 15.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KOS12911.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.8 KOS12911.1 - 0.063 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Mannosyl_trans PF05007.8 KOS12912.1 - 3.4e-56 190.7 21.5 9.9e-56 189.2 14.9 1.7 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) DEAD PF00270.24 KOS12913.1 - 6.8e-38 129.8 0.1 1.7e-37 128.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS12913.1 - 5.5e-26 90.2 0.0 1.3e-24 85.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS12913.1 - 1.2e-06 28.4 0.0 3.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KOS12913.1 - 0.0082 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L28 PF00830.14 KOS12914.1 - 7.8e-21 73.6 0.9 1.7e-20 72.5 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L28 family Sdh5 PF03937.11 KOS12915.1 - 3.8e-23 80.9 0.2 5.4e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase FHA PF00498.21 KOS12916.1 - 4.2e-15 55.6 0.0 8.1e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sushi_2 PF09014.5 KOS12916.1 - 0.0087 15.8 0.0 0.074 12.8 0.0 2.1 2 0 0 2 2 2 1 Beta-2-glycoprotein-1 fifth domain MIP-T3 PF10243.4 KOS12916.1 - 0.11 11.0 9.4 0.11 10.9 6.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF566 PF04484.7 KOS12916.1 - 1.6 8.1 9.6 1.8 8.0 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3827 PF12877.2 KOS12916.1 - 4.2 5.3 11.4 5.4 5.0 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) bZIP_1 PF00170.16 KOS12917.1 - 1.2e-07 31.6 10.8 2.8e-07 30.3 7.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KOS12917.1 - 1.1e-06 28.3 9.6 1.1e-06 28.3 6.6 2.1 1 1 1 2 2 2 2 Basic region leucine zipper Herpes_BLRF2 PF05812.7 KOS12917.1 - 0.0047 16.7 3.4 0.0091 15.8 0.3 2.2 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein bZIP_Maf PF03131.12 KOS12917.1 - 0.0092 16.2 8.7 0.017 15.4 6.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor AAA_13 PF13166.1 KOS12917.1 - 0.0093 14.4 3.1 0.012 14.0 2.1 1.1 1 0 0 1 1 1 1 AAA domain Phlebovirus_NSM PF07246.6 KOS12917.1 - 0.044 12.9 3.3 0.065 12.3 2.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ATG16 PF08614.6 KOS12917.1 - 0.07 12.9 14.6 0.032 14.0 8.0 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.8 KOS12917.1 - 0.077 12.9 0.3 0.077 12.9 0.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.3 KOS12917.1 - 0.12 12.1 6.1 0.11 12.3 0.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.6 KOS12917.1 - 0.28 11.0 4.5 0.98 9.3 3.1 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Phage_GP20 PF06810.6 KOS12917.1 - 0.42 10.0 7.6 1.1 8.6 0.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.6 KOS12917.1 - 1.5 6.2 6.8 7.8 3.8 4.8 1.8 1 1 0 1 1 1 0 Prominin Fib_alpha PF08702.5 KOS12917.1 - 2.1 8.4 7.8 14 5.8 4.9 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KOS12917.1 - 9.1 6.6 6.9 4.2 7.7 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DPBB_1 PF03330.13 KOS12918.1 - 0.0016 18.4 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ndc1_Nup PF09531.5 KOS12918.1 - 0.029 12.8 11.4 0.037 12.4 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Daxx PF03344.10 KOS12918.1 - 5 5.4 13.6 6.7 5.0 9.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 KOS12919.1 - 0.26 11.3 7.6 0.34 10.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 KOS12919.1 - 1.8 7.7 5.9 2 7.6 3.8 1.3 1 1 0 1 1 1 0 SDA1 DNA_pol_alpha_N PF12254.3 KOS12919.1 - 2.6 7.9 7.8 20 5.0 1.3 3.5 3 1 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal FYDLN_acid PF09538.5 KOS12919.1 - 4.5 7.8 10.7 6.8 7.3 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) RIC1 PF07064.8 KOS12920.1 - 2.8e-52 177.7 0.2 4.7e-52 177.0 0.1 1.3 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KOS12920.1 - 0.35 10.8 3.7 5.9 6.9 0.5 3.2 2 1 0 2 2 2 0 WD domain, G-beta repeat IBN_N PF03810.14 KOS12921.1 - 2.5e-14 52.9 0.0 1e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 KOS12921.1 - 9.2e-08 31.0 0.0 2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KOS12921.1 - 0.0024 17.7 2.1 0.019 14.9 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 KOS12921.1 - 0.0042 17.3 3.6 0.53 10.6 0.1 3.8 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 KOS12921.1 - 0.011 15.7 4.3 1.6 9.0 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.2 KOS12921.1 - 0.14 12.6 1.5 2.6 8.4 0.0 3.7 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region Fungal_trans PF04082.13 KOS12922.1 - 3.7e-06 25.9 0.2 9.5e-06 24.6 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS12922.1 - 1.6e-05 24.6 11.2 3.4e-05 23.6 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGEF PF00617.14 KOS12923.1 - 1.3e-42 145.6 0.0 1.9e-41 141.9 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KOS12923.1 - 1.9e-05 24.7 0.4 6.2e-05 23.0 0.3 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KOS12923.1 - 1.9e-05 23.9 0.0 3.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS12923.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS12923.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SGT1 PF07093.6 KOS12924.1 - 3e-113 379.2 2.9 5.1e-113 378.5 2.0 1.3 1 0 0 1 1 1 1 SGT1 protein Rad4 PF03835.10 KOS12925.1 - 8e-27 93.4 0.4 2.2e-26 92.0 0.3 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KOS12925.1 - 6.3e-21 73.8 0.0 1.1e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KOS12925.1 - 1e-16 60.1 0.2 1e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KOS12925.1 - 7.8e-15 54.9 0.8 3.3e-14 52.9 0.6 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KOS12925.1 - 1.9e-12 47.3 0.0 5.3e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily EDR1 PF14381.1 KOS12925.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Rad17 PF03215.10 KOS12926.1 - 2e-39 135.6 0.0 2.9e-27 95.5 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS12926.1 - 3.2e-07 30.5 0.0 6.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS12926.1 - 6.7e-07 29.4 0.5 2e-06 27.9 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KOS12926.1 - 0.00087 19.5 0.0 0.0034 17.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 KOS12926.1 - 0.0022 17.8 0.1 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KOS12926.1 - 0.005 17.0 0.0 0.0095 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KOS12926.1 - 0.0054 16.4 0.0 0.021 14.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KOS12926.1 - 0.0096 15.8 0.1 0.13 12.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS12926.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KOS12926.1 - 0.025 14.4 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KOS12926.1 - 0.029 14.6 0.0 0.072 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KOS12926.1 - 0.066 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 KOS12926.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arylesterase PF01731.15 KOS12928.1 - 0.11 12.5 0.0 16 5.5 0.0 3.2 3 0 0 3 3 3 0 Arylesterase G-patch_2 PF12656.2 KOS12930.1 - 1.8e-18 66.1 0.0 3.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 KOS12930.1 - 0.012 15.4 3.4 0.027 14.2 2.4 1.5 1 0 0 1 1 1 0 G-patch domain MBF1 PF08523.5 KOS12930.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Multiprotein bridging factor 1 CBS PF00571.23 KOS12931.1 - 7.3e-34 115.3 9.9 4.9e-08 32.6 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KOS12931.1 - 1.4e-06 27.8 0.1 3.4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 PB1 domain NYN PF01936.13 KOS12931.1 - 0.028 14.6 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 NYN domain 4HBT_3 PF13622.1 KOS12932.1 - 9.8e-35 120.5 0.4 1.4e-34 120.0 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily SUA5 PF03481.8 KOS12933.1 - 0.049 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding AKNA PF12443.3 KOS12933.1 - 0.069 13.1 7.2 0.28 11.2 0.2 2.8 2 1 0 2 2 2 0 AT-hook-containing transcription factor Prefoldin PF02996.12 KOS12933.1 - 0.07 12.7 9.0 1.1 8.9 0.7 3.8 2 1 2 4 4 4 0 Prefoldin subunit Spc7 PF08317.6 KOS12933.1 - 2.5 6.6 12.2 0.34 9.5 1.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.10 KOS12933.1 - 4.2 6.9 11.2 3.4 7.2 0.8 3.0 3 0 0 3 3 3 0 Septum formation initiator TBPIP PF07106.8 KOS12933.1 - 4.4 6.8 8.5 2.3 7.7 1.0 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3782 PF12644.2 KOS12933.1 - 8.5 6.2 6.7 2.7 7.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) GAS PF13851.1 KOS12933.1 - 9 5.4 11.1 7 5.7 0.5 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 KOS12933.1 - 9.2 5.8 9.4 1.4 8.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AMPKBI PF04739.10 KOS12934.1 - 1.1e-25 89.3 0.1 1.1e-25 89.3 0.0 2.5 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain PHD PF00628.24 KOS12935.1 - 8.8e-11 41.3 23.5 1.8e-05 24.3 1.6 3.8 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.1 KOS12935.1 - 0.88 9.7 8.2 0.11 12.6 1.9 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 KOS12935.1 - 3.2 7.0 10.0 13 5.0 2.9 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain TGS PF02824.16 KOS12936.1 - 4.5e-19 68.0 0.1 8e-19 67.2 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KOS12936.1 - 1.5e-17 63.6 0.0 3.1e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS12936.1 - 9.8e-11 41.1 0.0 1.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS12936.1 - 0.00065 19.5 0.2 0.2 11.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KOS12936.1 - 0.00075 19.9 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KOS12936.1 - 0.011 15.6 0.2 0.031 14.2 0.2 1.8 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KOS12936.1 - 0.027 13.2 0.3 0.063 12.0 0.1 1.7 1 1 1 2 2 2 0 ArgK protein AIG1 PF04548.11 KOS12936.1 - 0.043 12.9 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MCM PF00493.18 KOS12936.1 - 0.046 12.5 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family CorA PF01544.13 KOS12937.1 - 2.6e-44 151.4 1.1 3.5e-44 151.0 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 KOS12937.1 - 0.038 14.3 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 ACT domain DUF3826 PF12875.2 KOS12937.1 - 0.041 13.5 0.3 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) Mito_carr PF00153.22 KOS12938.1 - 3.5e-57 190.1 3.4 5e-19 67.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TRIC PF05197.8 KOS12939.1 - 0.00056 19.3 0.3 0.00099 18.5 0.2 1.4 1 0 0 1 1 1 1 TRIC channel HAD_2 PF13419.1 KOS12940.1 - 4e-13 49.9 0.0 5.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS12940.1 - 6.3e-09 36.5 0.0 1.2e-08 35.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS12940.1 - 6.2e-07 29.0 0.0 2.5e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 KOS12940.1 - 0.00063 19.9 0.0 0.00066 19.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_1_2 PF13603.1 KOS12940.1 - 0.026 13.8 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 HAD_2 PF13419.1 KOS12941.1 - 4.6e-11 43.2 0.0 9.8e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS12941.1 - 1.3e-08 34.4 0.1 1e-07 31.5 0.1 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 KOS12941.1 - 1.3e-06 29.0 0.0 3.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS12941.1 - 0.0011 19.1 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rrp15p PF07890.7 KOS12942.1 - 8.8e-28 96.9 1.2 8.8e-28 96.9 0.8 1.9 1 1 1 2 2 2 1 Rrp15p CENP-B_dimeris PF09026.5 KOS12942.1 - 0.021 15.0 6.4 0.042 14.0 4.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Phage_int_SAM_2 PF12834.2 KOS12942.1 - 0.024 15.0 1.8 3.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal F-protein PF00469.15 KOS12942.1 - 0.14 11.4 8.3 1.3 8.3 1.6 2.2 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Nucleoplasmin PF03066.10 KOS12942.1 - 0.38 10.2 4.6 0.68 9.4 3.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin HGTP_anticodon2 PF12745.2 KOS12942.1 - 0.38 9.8 5.9 0.049 12.7 1.0 1.7 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Myc_N PF01056.13 KOS12942.1 - 2.1 7.4 8.7 0.49 9.4 3.7 1.7 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.9 KOS12942.1 - 2.4 6.1 9.2 0.32 8.9 3.8 1.4 2 0 0 2 2 2 0 CDC45-like protein ATP11 PF06644.6 KOS12942.1 - 3.5 7.0 8.4 1.7 8.0 0.5 2.1 2 0 0 2 2 2 0 ATP11 protein SQS_PSY PF00494.14 KOS12943.1 - 2.6e-39 135.1 0.0 3.8e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3782 PF12644.2 KOS12943.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Mito_carr PF00153.22 KOS12944.1 - 4.9e-54 180.0 0.1 6.3e-18 64.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_23 PF13489.1 KOS12945.1 - 1.4e-11 44.3 0.0 2.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS12945.1 - 3.4e-11 43.7 0.0 6.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS12945.1 - 2.8e-10 40.5 0.0 8.3e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12945.1 - 9.4e-10 38.8 0.0 1.1e-08 35.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS12945.1 - 3e-07 30.1 0.0 2e-06 27.4 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12945.1 - 1e-05 25.5 0.1 8.3e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS12945.1 - 5.5e-05 23.4 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS12945.1 - 0.02 14.0 0.0 0.057 12.5 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 KOS12945.1 - 0.04 14.7 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KOS12945.1 - 0.047 12.6 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DEAD PF00270.24 KOS12946.1 - 5.8e-46 156.0 0.0 7.2e-44 149.2 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Pkinase PF00069.20 KOS12946.1 - 1e-38 132.9 0.0 1.9e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Helicase_C PF00271.26 KOS12946.1 - 3.1e-27 94.2 0.0 9e-27 92.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase_Tyr PF07714.12 KOS12946.1 - 5.6e-13 48.5 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase ResIII PF04851.10 KOS12946.1 - 0.0011 18.7 0.0 0.0055 16.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_ser-thr_kin PF05445.6 KOS12946.1 - 0.003 16.4 0.0 0.0051 15.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Helicase_C_2 PF13307.1 KOS12946.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KOS12946.1 - 0.11 10.8 0.0 0.74 8.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) DUF747 PF05346.6 KOS12947.1 - 8.3e-114 380.0 6.6 1.3e-113 379.4 4.6 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family Brix PF04427.13 KOS12948.1 - 5.8e-48 163.0 0.2 7.5e-48 162.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain Mito_carr PF00153.22 KOS12949.1 - 1.1e-60 201.3 6.9 3.9e-21 74.5 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 KOS12949.1 - 0.00016 21.2 2.3 0.0018 18.0 0.1 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 KOS12949.1 - 0.00094 19.2 2.5 0.0027 17.8 0.3 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KOS12949.1 - 0.0011 18.1 2.7 0.016 14.4 0.2 3.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KOS12949.1 - 0.033 13.7 2.1 0.054 13.1 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 KOS12949.1 - 0.044 13.1 0.3 0.044 13.1 0.2 2.3 3 0 0 3 3 3 0 EF hand PGAP1 PF07819.8 KOS12950.1 - 2.5e-08 33.7 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KOS12950.1 - 2.3e-05 23.8 0.0 5.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KOS12950.1 - 0.00049 20.0 1.1 0.0028 17.5 0.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS12950.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TetR_C PF02909.12 KOS12950.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain LCAT PF02450.10 KOS12950.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cu-oxidase_3 PF07732.10 KOS12951.1 - 5e-33 113.3 7.1 6.3e-22 77.5 0.3 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS12951.1 - 2.8e-30 104.6 11.3 6e-30 103.5 2.7 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS12951.1 - 2.7e-29 102.1 0.0 1.7e-27 96.2 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 KOS12952.1 - 1.8e-37 128.8 41.6 1.8e-37 128.8 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S26 PF10502.4 KOS12953.1 - 8.8e-10 38.2 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KOS12953.1 - 6.4e-08 32.1 0.0 2.1e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like PDZ_2 PF13180.1 KOS12953.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Cu-oxidase_3 PF07732.10 KOS12954.1 - 1.7e-33 114.8 6.8 5.9e-23 80.8 0.8 3.4 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS12954.1 - 1.4e-31 109.5 0.0 1.1e-29 103.4 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS12954.1 - 5.6e-31 106.8 3.9 5.6e-31 106.8 2.7 2.9 2 1 0 2 2 2 1 Multicopper oxidase CarD_CdnL_TRCF PF02559.11 KOS12954.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 CarD-like/TRCF domain SRF-TF PF00319.13 KOS12955.1 - 2.2e-21 74.8 0.0 4.1e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) YTH PF04146.10 KOS12956.1 - 1.5e-15 57.0 0.0 2.6e-15 56.2 0.0 1.2 1 1 0 1 1 1 1 YT521-B-like domain adh_short_C2 PF13561.1 KOS12957.1 - 9.6e-26 91.0 0.0 1.3e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS12957.1 - 9.8e-25 87.3 0.1 1.4e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS12957.1 - 7.7e-11 41.9 0.1 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 KOS12957.1 - 0.0019 18.5 0.2 0.0055 17.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KOS12957.1 - 0.0025 17.6 0.6 0.0063 16.3 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KOS12957.1 - 0.0045 15.7 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 KOS12957.1 - 0.031 14.8 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Lactamase_B PF00753.22 KOS12958.1 - 5.3e-20 71.8 0.7 1.1e-19 70.8 0.5 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS12958.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LIP PF03583.9 KOS12959.1 - 2.7e-66 223.7 0.0 3.5e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KOS12959.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS12959.1 - 0.002 17.9 0.0 0.0041 16.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ubiquitin PF00240.18 KOS12960.1 - 2.1e-09 36.6 0.0 2.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS12960.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KOS12960.1 - 0.00017 21.7 0.0 0.001 19.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 KOS12960.1 - 0.0061 17.1 0.0 0.0096 16.4 0.0 1.4 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.3 KOS12960.1 - 0.039 14.2 0.0 0.067 13.4 0.0 1.4 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Fer2_3 PF13085.1 KOS12961.1 - 5.9e-32 109.7 0.0 8.9e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KOS12961.1 - 1.4e-09 38.1 5.8 1.4e-09 38.1 4.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KOS12961.1 - 2e-09 37.3 4.8 2e-09 37.3 3.4 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KOS12961.1 - 6.3e-05 23.1 2.3 0.068 13.4 0.2 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 KOS12961.1 - 0.00027 21.2 3.0 0.00027 21.2 2.1 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KOS12961.1 - 0.00096 18.8 0.2 0.00096 18.8 0.2 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 KOS12961.1 - 0.0012 18.6 8.3 0.0013 18.4 4.0 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 KOS12961.1 - 0.0075 16.6 5.4 0.0075 16.6 3.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 KOS12961.1 - 2.2 8.9 8.2 2 9.0 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Mito_carr PF00153.22 KOS12962.1 - 2.2e-66 219.5 4.8 2.1e-24 85.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rib_5-P_isom_A PF06026.9 KOS12963.1 - 1.6e-55 187.0 0.1 2e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF3606 PF12244.3 KOS12963.1 - 0.041 13.5 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Mito_carr PF00153.22 KOS12964.1 - 2.7e-38 129.5 0.1 3e-24 84.5 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3321 PF11968.3 KOS12965.1 - 7.3e-58 195.7 0.0 9.2e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KOS12965.1 - 2.2e-09 37.2 0.0 6.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12965.1 - 1.3e-05 25.5 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KOS12965.1 - 0.00014 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.1 KOS12965.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KOS12965.1 - 0.032 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Hydrolase_6 PF13344.1 KOS12965.1 - 0.058 13.2 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4158 PF13700.1 KOS12965.1 - 0.1 12.0 0.2 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) PHP PF02811.14 KOS12966.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PHP domain Bromodomain PF00439.20 KOS12967.1 - 1.3e-21 76.3 0.1 2.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Epsilon_antitox PF08998.6 KOS12967.1 - 0.094 12.7 1.3 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin Maf1 PF09174.5 KOS12967.1 - 1.5 8.6 4.4 0.53 10.1 0.2 2.0 2 0 0 2 2 2 0 Maf1 regulator Pkinase PF00069.20 KOS12968.1 - 5.1e-65 219.1 0.0 1.1e-64 218.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS12968.1 - 1.6e-34 119.1 0.0 2.3e-33 115.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS12968.1 - 4.2e-07 29.2 0.1 3.2e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KOS12968.1 - 0.00018 20.4 0.1 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DUF1675 PF07897.6 KOS12968.1 - 0.09 12.6 4.0 0.17 11.7 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MAD PF05557.8 KOS12969.1 - 1.1e-35 122.9 48.5 3.9e-35 121.1 33.7 1.7 1 1 0 1 1 1 1 Mitotic checkpoint protein Kinetocho_Slk19 PF12709.2 KOS12969.1 - 0.44 10.6 0.0 0.44 10.6 0.0 6.5 7 0 0 7 7 7 0 Central kinetochore-associated YojJ PF10372.4 KOS12969.1 - 1 9.2 0.0 1 9.2 0.0 3.2 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus CCDC155 PF14662.1 KOS12969.1 - 2.5 7.6 58.0 0.03 13.9 8.2 6.2 4 3 1 5 5 5 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 KOS12969.1 - 6.6 5.2 47.9 0.19 10.3 4.4 5.0 3 1 1 5 5 5 0 Spc7 kinetochore protein HOOK PF05622.7 KOS12969.1 - 7.7 4.1 58.6 0.068 10.9 10.6 3.3 2 1 1 3 3 3 0 HOOK protein Sod_Fe_N PF00081.17 KOS12970.1 - 1.9e-34 117.7 2.9 1.9e-34 117.7 2.0 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 KOS12970.1 - 6.3e-34 116.0 2.7 1.1e-33 115.2 1.8 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Kinesin PF00225.18 KOS12971.1 - 3e-83 279.3 1.3 3.6e-83 279.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Reo_sigmaC PF04582.7 KOS12971.1 - 0.0065 15.6 0.8 0.0065 15.6 0.5 1.9 2 0 0 2 2 2 1 Reovirus sigma C capsid protein ERM PF00769.14 KOS12971.1 - 0.011 15.2 17.6 0.011 15.2 12.2 2.5 2 1 0 3 3 2 0 Ezrin/radixin/moesin family FH2 PF02181.18 KOS12971.1 - 0.024 13.5 5.1 0.043 12.6 3.5 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain EzrA PF06160.7 KOS12971.1 - 0.048 11.8 12.7 0.077 11.1 8.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KOS12971.1 - 0.15 10.6 8.7 0.29 9.7 6.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KOS12971.1 - 0.17 11.7 6.0 3.4 7.6 0.0 3.4 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) Seadorna_VP6 PF07407.6 KOS12971.1 - 0.19 10.4 1.1 0.29 9.8 0.7 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Shugoshin_N PF07558.6 KOS12971.1 - 0.25 11.1 3.0 0.22 11.2 0.6 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3450 PF11932.3 KOS12971.1 - 0.37 10.0 18.2 0.035 13.3 8.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TEX13 PF15186.1 KOS12971.1 - 0.55 9.7 22.9 1.3 8.5 0.4 3.6 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family TBPIP PF07106.8 KOS12971.1 - 0.82 9.1 11.0 4 6.9 0.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 KOS12971.1 - 0.85 9.3 22.5 0.59 9.8 11.3 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 KOS12971.1 - 0.92 9.2 8.9 0.083 12.6 1.9 2.4 2 1 1 3 3 2 0 Laminin Domain II IncA PF04156.9 KOS12971.1 - 1.1 8.8 32.2 0.047 13.2 12.6 2.5 2 0 0 2 2 2 0 IncA protein CCDC92 PF14916.1 KOS12971.1 - 1.3 8.6 11.9 1.5 8.4 3.9 2.9 1 1 0 2 2 2 0 Coiled-coil domain of unknown function CENP-F_leu_zip PF10473.4 KOS12971.1 - 1.6 8.5 25.7 0.036 13.9 4.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2317 PF10079.4 KOS12971.1 - 1.9 6.9 21.3 2 6.9 8.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) UPF0242 PF06785.6 KOS12971.1 - 3 6.4 11.2 5.4 5.5 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) V_ATPase_I PF01496.14 KOS12971.1 - 4.1 5.1 12.9 9.8 3.8 9.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 KOS12971.1 - 7 5.5 8.5 16 4.4 5.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.7 KOS12971.1 - 7.6 6.3 7.5 2 8.2 1.9 2.4 3 1 0 3 3 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KOS12971.1 - 8.1 6.8 18.4 2.5 8.4 2.3 4.1 4 1 1 5 5 4 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 KOS12971.1 - 8.2 6.2 25.9 0.13 12.0 12.0 2.3 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 KOS12971.1 - 8.7 6.2 28.1 0.16 11.8 4.7 3.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KOS12971.1 - 9.9 6.5 27.0 0.44 10.8 2.7 3.5 2 1 1 3 3 2 0 Protein of unknown function (DUF904) Elongin_A PF06881.6 KOS12972.1 - 6.3e-17 61.9 0.0 8e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNB PF00773.14 KOS12973.1 - 1.1e-30 107.0 0.0 1.9e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KOS12973.1 - 0.3 10.6 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain MFS_1 PF07690.11 KOS12974.1 - 2.4e-11 42.9 19.0 2.7e-11 42.7 13.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 KOS12974.1 - 0.014 15.0 9.6 0.023 14.3 3.6 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Med11 PF10280.4 KOS12975.1 - 7.4e-08 32.4 0.0 8.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein WXG100 PF06013.7 KOS12975.1 - 0.0087 16.0 1.6 0.031 14.2 1.1 2.0 1 1 0 1 1 1 1 Proteins of 100 residues with WXG Ribosomal_S8 PF00410.14 KOS12976.1 - 3.7e-21 75.3 0.0 5.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MDMPI_C PF07398.6 KOS12976.1 - 0.093 13.3 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 MDMPI C-terminal domain Methyltransf_18 PF12847.2 KOS12977.1 - 7.3e-08 32.9 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS12977.1 - 2.9e-06 26.9 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS12977.1 - 0.00014 22.3 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS12977.1 - 0.00076 19.2 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12977.1 - 0.00078 19.8 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS12977.1 - 0.0073 15.9 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS12977.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KOS12977.1 - 0.047 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.1 KOS12978.1 - 1.2e-11 44.4 0.0 2.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS12978.1 - 5.6e-11 43.0 0.0 8.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KOS12978.1 - 6.2e-07 29.1 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS12978.1 - 1.4e-06 28.6 0.0 4.1e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12978.1 - 2.9e-06 27.3 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS12978.1 - 5.9e-05 23.3 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS12978.1 - 0.00062 20.2 0.0 0.0018 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS12978.1 - 0.0024 17.6 0.0 0.0054 16.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS12978.1 - 0.0052 16.1 0.0 0.014 14.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_28 PF02636.12 KOS12978.1 - 0.042 13.2 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyl-CoA_dh_1 PF00441.19 KOS12979.1 - 1.5e-46 158.2 3.2 2.3e-46 157.6 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS12979.1 - 7e-27 94.2 0.1 1.7e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KOS12979.1 - 2.6e-24 84.4 0.4 5.7e-24 83.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KOS12979.1 - 2.9e-14 53.4 1.5 5e-14 52.7 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KOS12979.1 - 0.0022 17.4 0.0 0.0095 15.3 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Mor PF08765.6 KOS12979.1 - 0.0034 17.1 0.2 0.72 9.6 0.0 2.5 2 0 0 2 2 2 2 Mor transcription activator family Asp PF00026.18 KOS12980.1 - 6.4e-109 364.0 0.0 7.6e-109 363.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS12980.1 - 5.6e-09 36.1 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KOS12980.1 - 1.8e-08 34.0 0.0 4.5e-07 29.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KOS12980.1 - 0.00016 22.1 0.0 0.08 13.4 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease Leo1 PF04004.8 KOS12981.1 - 1.5e-49 168.0 0.0 3.2e-49 166.9 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein Baculo_PEP_C PF04513.7 KOS12982.1 - 0.19 11.5 6.5 3.8 7.3 0.2 3.9 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 KOS12982.1 - 0.3 8.5 3.7 0.76 7.2 2.6 1.7 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 KOS12982.1 - 0.51 10.2 9.6 15 5.5 0.1 4.5 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KOS12982.1 - 0.56 10.4 9.0 26 5.1 0.3 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 KOS12982.1 - 1.2 7.9 40.3 0.012 14.6 8.4 4.3 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4239 PF14023.1 KOS12982.1 - 5.5 6.2 8.1 1.6 8.0 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) EHN PF06441.7 KOS12982.1 - 5.6 6.9 6.6 3.3 7.6 0.5 3.4 3 1 0 3 3 3 0 Epoxide hydrolase N terminus DUF3138 PF11336.3 KOS12982.1 - 8.2 4.4 7.7 5.2 5.1 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) DUF2413 PF10310.4 KOS12983.1 - 2.1e-37 129.0 6.7 4.1e-37 128.0 4.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) ORC2 PF04084.9 KOS12984.1 - 1.1e-38 132.8 0.0 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Peptidase_C48 PF02902.14 KOS12985.1 - 1e-37 129.8 0.1 2.6e-37 128.5 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Vps51 PF08700.6 KOS12986.1 - 2.3e-11 43.3 0.8 6.8e-11 41.8 0.5 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KOS12986.1 - 0.033 14.0 0.2 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YlbD_coat PF14071.1 KOS12986.1 - 0.18 11.8 1.0 0.49 10.4 0.7 1.7 1 0 0 1 1 1 0 Putative coat protein FBP PF07299.6 KOS12986.1 - 0.28 10.4 0.4 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Sec23_trunk PF04811.10 KOS12987.1 - 1.1e-72 244.2 0.0 1.6e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KOS12987.1 - 2.4e-35 120.0 0.3 4.2e-35 119.2 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KOS12987.1 - 1.6e-30 105.4 0.0 3.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KOS12987.1 - 3.3e-17 61.7 6.8 7e-17 60.7 4.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KOS12987.1 - 2.8e-12 46.1 0.0 5.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat FDF PF09532.5 KOS12988.1 - 1e-05 26.0 0.1 1e-05 26.0 0.1 2.2 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KOS12988.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 KOS12988.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 LSM domain SOBP PF15279.1 KOS12988.1 - 0.13 12.6 4.5 0.18 12.1 3.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RabGAP-TBC PF00566.13 KOS12989.1 - 6.9e-46 156.4 0.5 8.9e-45 152.7 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PRMT5 PF05185.11 KOS12990.1 - 2.5e-11 43.1 0.0 3.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 KOS12990.1 - 6.7e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS12990.1 - 0.00024 21.0 0.0 0.027 14.5 0.1 2.6 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KOS12990.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KOS12990.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS12990.1 - 0.015 14.7 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KOS12990.1 - 0.052 14.0 0.0 0.95 9.9 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain DREV PF05219.7 KOS12990.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DDHD PF02862.12 KOS12992.1 - 1e-31 110.5 0.3 3.7e-16 59.6 0.0 3.2 2 1 1 3 3 3 2 DDHD domain Glyco_hydro_16 PF00722.16 KOS12993.1 - 2e-21 76.1 0.3 4.5e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKG6 PF08693.5 KOS12993.1 - 0.057 12.7 0.6 0.1 11.9 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IncA PF04156.9 KOS12993.1 - 0.086 12.4 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 IncA protein Glt_symporter PF03616.9 KOS12993.1 - 0.11 11.0 0.1 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Ecl1 PF12855.2 KOS12994.1 - 3.6e-07 29.3 0.7 1.2e-06 27.6 0.5 1.8 1 1 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KOS12994.1 - 0.024 14.2 0.2 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2116 PF09889.4 KOS12994.1 - 0.15 11.8 0.3 5.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MOZ_SAS PF01853.13 KOS12995.1 - 1.8e-61 206.6 0.0 2.3e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 KOS12995.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Metallophos PF00149.23 KOS12996.1 - 1.1e-07 31.5 3.4 1.9e-07 30.6 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CPSF_A PF03178.10 KOS12998.1 - 4.5e-56 190.2 0.0 8.2e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KOS12998.1 - 0.0013 17.0 0.0 0.58 8.2 0.0 3.0 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term DnaJ PF00226.26 KOS12999.1 - 2.4e-24 84.8 1.0 4.6e-24 83.9 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KOS12999.1 - 1.5e-16 60.5 4.1 5.5e-10 39.4 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1977) MIT PF04212.13 KOS12999.1 - 0.53 10.1 3.0 0.84 9.5 0.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_L30 PF00327.15 KOS13000.1 - 5.5e-15 54.6 0.2 8.4e-15 54.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e EF1_GNE PF00736.14 KOS13001.1 - 3.3e-31 106.8 4.0 6.2e-31 105.9 2.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KOS13001.1 - 1.5e-12 47.3 6.3 5.4e-12 45.6 4.4 2.0 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KOS13001.1 - 0.00021 21.7 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS13001.1 - 0.02 14.7 0.0 0.1 12.4 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS13001.1 - 0.044 13.7 0.2 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 KOS13002.1 - 8e-37 124.8 6.3 7.8e-16 57.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ETF PF01012.16 KOS13003.1 - 5.2e-36 123.8 1.2 6.9e-36 123.4 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EFG_C PF00679.19 KOS13003.1 - 0.14 12.0 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor G C-terminus ELFV_dehydrog PF00208.16 KOS13004.1 - 4.8e-50 170.4 0.0 8.1e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KOS13004.1 - 8.3e-26 89.8 0.0 5.1e-18 64.0 0.0 2.8 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KOS13004.1 - 0.005 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PGM_PMM_I PF02878.11 KOS13005.1 - 2.6e-37 127.3 0.1 4.3e-37 126.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KOS13005.1 - 2.4e-26 91.9 0.0 4.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KOS13005.1 - 4.2e-18 65.6 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KOS13005.1 - 1e-09 38.2 0.0 2.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_m1G_MT PF01746.16 KOS13006.1 - 1.5e-23 83.3 0.0 1.2e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Ribosomal_L22 PF00237.14 KOS13007.1 - 1.6e-32 111.5 0.1 1.6e-32 111.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e TFIID-31kDa PF02291.10 KOS13008.1 - 2.8e-43 146.7 0.0 3.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KOS13008.1 - 4e-05 23.2 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KOS13008.1 - 0.053 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF726 PF05277.7 KOS13009.1 - 3.1e-116 388.0 0.7 5.5e-116 387.2 0.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KOS13009.1 - 0.00032 20.4 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS13009.1 - 0.0018 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KOS13009.1 - 0.015 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KOS13009.1 - 0.078 12.5 0.5 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS13009.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Sec1 PF00995.18 KOS13010.1 - 1e-137 460.1 0.0 1.2e-137 459.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DCP2 PF05026.8 KOS13012.1 - 3.3e-26 90.9 0.0 6e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KOS13012.1 - 3.2e-14 52.7 0.1 9.5e-14 51.1 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain SUI1 PF01253.17 KOS13013.1 - 7.5e-30 102.5 1.2 9.4e-30 102.2 0.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 ALAD PF00490.16 KOS13014.1 - 1.9e-108 362.1 0.0 2.2e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Ribosomal_L44 PF00935.14 KOS13015.1 - 7.3e-35 118.8 12.0 1.1e-34 118.2 8.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Slu7 PF11708.3 KOS13016.1 - 1.4e-70 237.7 21.9 2.5e-70 236.9 15.2 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor YL1 PF05764.8 KOS13016.1 - 0.12 12.0 18.4 0.38 10.3 12.5 1.8 1 1 1 2 2 2 0 YL1 nuclear protein AA_permease_2 PF13520.1 KOS13017.1 - 1.9e-56 191.4 48.5 2.4e-56 191.0 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS13017.1 - 1.6e-07 30.0 41.0 2.6e-07 29.3 28.4 1.2 1 0 0 1 1 1 1 Amino acid permease IF4E PF01652.13 KOS13018.1 - 2.3e-48 163.8 0.2 3e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Complex1_LYR_2 PF13233.1 KOS13019.1 - 0.00025 21.5 0.4 0.00032 21.1 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like SGS PF05002.10 KOS13019.1 - 0.066 12.9 0.9 0.79 9.5 0.1 2.1 1 1 1 2 2 2 0 SGS domain End_N_terminal PF12218.3 KOS13020.1 - 0.094 12.1 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Arf PF00025.16 KOS13021.1 - 1.4e-65 219.7 0.0 1.9e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS13021.1 - 7.4e-10 38.3 0.0 2.2e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KOS13021.1 - 6.4e-09 34.9 0.3 9.8e-06 24.4 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KOS13021.1 - 4.1e-08 33.7 0.0 8.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KOS13021.1 - 5.1e-07 29.6 0.0 2.6e-06 27.3 0.0 2.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Ras PF00071.17 KOS13021.1 - 8.6e-07 28.4 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ras family KOW PF00467.24 KOS13021.1 - 4.5e-06 26.1 0.4 4.5e-06 26.1 0.3 2.0 2 0 0 2 2 2 1 KOW motif Gtr1_RagA PF04670.7 KOS13021.1 - 5.7e-05 22.3 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS13021.1 - 0.016 14.6 0.1 0.68 9.3 0.0 2.8 1 1 1 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KOS13021.1 - 0.037 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 KOS13022.1 - 5.2e-37 127.4 0.0 7.2e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13022.1 - 5.6e-29 100.9 0.0 7.5e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS13022.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.8 3 2 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS13022.1 - 0.075 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Myosin_head PF00063.16 KOS13023.1 - 1.3e-228 760.5 0.1 2.1e-228 759.8 0.1 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KOS13023.1 - 5e-38 130.4 0.0 6.1e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KOS13023.1 - 6.2e-13 47.9 0.7 5.4e-12 44.8 0.2 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KOS13023.1 - 9.5e-12 44.2 0.1 3.9e-09 35.8 0.0 2.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KOS13023.1 - 4.5e-11 42.1 0.9 1.7e-10 40.2 0.3 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_3 PF08239.6 KOS13023.1 - 0.00045 20.3 0.6 0.0011 19.0 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.7 KOS13023.1 - 0.0026 17.0 0.2 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KOS13023.1 - 0.0043 17.1 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS13023.1 - 0.014 16.2 0.3 0.07 13.9 0.0 2.5 3 0 0 3 3 1 0 AAA domain Zeta_toxin PF06414.7 KOS13023.1 - 0.024 13.7 0.0 0.061 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KOS13023.1 - 0.074 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 KOS13023.1 - 0.1 12.1 0.2 0.36 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KOS13023.1 - 0.19 12.0 0.0 0.6 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain IQ PF00612.22 KOS13023.1 - 0.63 9.8 15.4 0.19 11.4 3.2 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif RNase_PH PF01138.16 KOS13025.1 - 3.9e-17 62.7 0.0 7.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS13025.1 - 1.7e-07 31.0 0.0 3.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DEAD PF00270.24 KOS13027.1 - 1.5e-46 157.9 0.0 2.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13027.1 - 8.6e-26 89.6 0.0 2e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TPR_14 PF13428.1 KOS13028.1 - 3.3e-17 61.4 24.0 0.0087 16.6 0.0 12.6 5 2 10 15 15 15 3 Tetratricopeptide repeat HAT PF02184.11 KOS13028.1 - 4.9e-16 58.1 53.7 8.2e-07 28.6 0.2 13.9 14 0 0 14 14 14 7 HAT (Half-A-TPR) repeat Suf PF05843.9 KOS13028.1 - 3.9e-13 49.7 10.4 0.026 14.2 0.4 6.8 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KOS13028.1 - 5.2e-10 39.5 0.2 2.5 8.5 0.0 6.7 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13028.1 - 6.1e-10 38.2 3.4 0.47 10.4 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS13028.1 - 2.6e-07 30.2 6.6 0.2 11.3 0.0 6.2 6 2 1 7 7 7 2 TPR repeat TPR_12 PF13424.1 KOS13028.1 - 2.9e-07 30.3 11.7 0.98 9.4 0.5 6.8 7 1 2 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13028.1 - 5.6e-07 30.0 17.6 0.0018 18.9 0.0 8.2 7 2 4 11 11 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS13028.1 - 4.7e-06 26.3 2.2 0.014 15.5 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13028.1 - 4.9e-05 22.7 0.5 8.7 6.1 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13028.1 - 0.0014 18.2 0.8 13 5.8 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KOS13028.1 - 0.027 14.2 15.2 0.2 11.4 0.2 5.5 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.6 KOS13028.1 - 1.8 8.3 13.1 2.1 8.1 0.0 5.8 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 ING PF12998.2 KOS13029.1 - 1.5e-10 41.2 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KOS13029.1 - 5e-09 35.7 7.1 7.8e-09 35.0 4.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KOS13029.1 - 0.043 13.9 0.2 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KOS13029.1 - 0.25 10.7 2.9 0.42 9.9 2.0 1.3 1 0 0 1 1 1 0 PHD-finger CTP_transf_1 PF01148.15 KOS13030.1 - 4.2e-18 65.9 6.8 2.5e-14 53.5 0.9 2.6 1 1 1 2 2 2 2 Cytidylyltransferase family Prefoldin_2 PF01920.15 KOS13031.1 - 1.3e-19 69.8 5.5 1.4e-19 69.7 3.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KOS13031.1 - 0.0034 17.1 1.0 0.055 13.2 0.2 2.1 2 0 0 2 2 2 1 Prefoldin subunit STAT_alpha PF01017.15 KOS13031.1 - 0.0088 15.7 5.4 0.061 13.0 0.2 2.1 2 0 0 2 2 2 1 STAT protein, all-alpha domain DUF16 PF01519.11 KOS13031.1 - 0.051 13.8 0.6 0.082 13.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF720 PF05302.6 KOS13031.1 - 0.052 13.3 7.2 0.23 11.2 5.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Med11 PF10280.4 KOS13031.1 - 0.058 13.4 1.0 0.083 12.9 0.7 1.3 1 0 0 1 1 1 0 Mediator complex protein TPR_MLP1_2 PF07926.7 KOS13031.1 - 0.064 13.0 5.0 0.4 10.4 0.6 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.4 KOS13031.1 - 0.1 11.7 4.2 0.16 11.1 2.9 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 CENP-F_leu_zip PF10473.4 KOS13031.1 - 0.1 12.4 6.0 0.094 12.5 1.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 KOS13031.1 - 0.16 11.6 4.4 0.15 11.7 0.4 2.0 2 0 0 2 2 2 0 Prefoldin subunit RmuC PF02646.11 KOS13031.1 - 0.18 10.5 4.1 2.6 6.8 0.2 2.0 2 0 0 2 2 2 0 RmuC family ERp29 PF07749.7 KOS13031.1 - 0.24 12.0 2.9 0.84 10.3 2.0 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Fib_alpha PF08702.5 KOS13031.1 - 0.36 10.9 5.5 0.69 10.0 0.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2802 PF10975.3 KOS13031.1 - 0.42 10.4 4.6 8.7 6.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) TBPIP PF07106.8 KOS13031.1 - 0.47 9.9 6.9 0.28 10.7 0.4 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Suppressor_APC PF11414.3 KOS13031.1 - 0.49 10.2 6.1 1.3 8.8 0.3 2.3 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DivIVA PF05103.8 KOS13031.1 - 0.6 10.1 7.2 2.2 8.3 1.0 2.1 2 0 0 2 2 2 0 DivIVA protein FliJ PF02050.11 KOS13031.1 - 0.88 9.6 7.7 2.1 8.4 0.9 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF1192 PF06698.6 KOS13031.1 - 0.92 9.3 3.8 0.35 10.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 KOS13031.1 - 0.95 9.8 9.4 86 3.5 6.5 2.1 1 1 0 1 1 1 0 Snapin/Pallidin FlxA PF14282.1 KOS13031.1 - 1.3 8.9 8.2 0.29 11.0 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein APG6 PF04111.7 KOS13031.1 - 1.4 7.8 4.9 2.1 7.3 3.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KOS13031.1 - 1.6 8.5 8.6 19 5.0 6.0 2.0 1 1 0 1 1 1 0 Tropomyosin like DUF4140 PF13600.1 KOS13031.1 - 1.6 9.2 5.1 0.75 10.2 0.7 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.11 KOS13031.1 - 2 8.2 6.6 2.6 7.8 2.7 2.5 1 1 2 3 3 3 0 Hr1 repeat Spc24 PF08286.6 KOS13031.1 - 2.5 7.8 6.1 1.4 8.5 0.5 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 KOS13031.1 - 2.5 7.9 9.3 11 5.9 5.8 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KOS13031.1 - 3.5 7.1 10.3 10 5.6 7.2 1.7 1 1 0 1 1 1 0 IncA protein GDC-P PF02347.11 KOS13032.1 - 7.5e-182 604.7 4.4 1.3e-173 577.6 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KOS13032.1 - 6.6e-07 28.7 0.3 1.6e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Meth_synt_2 PF01717.13 KOS13033.1 - 3.7e-141 469.7 0.0 9.6e-137 455.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KOS13033.1 - 1.3e-122 408.9 0.0 3.6e-110 368.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 KOS13033.1 - 0.0021 17.4 0.6 0.0047 16.3 0.4 1.7 1 0 0 1 1 1 1 Short C-terminal domain Pkinase PF00069.20 KOS13034.1 - 1.6e-61 207.7 0.1 5.4e-41 140.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13034.1 - 7.7e-27 93.9 0.0 8.5e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS13034.1 - 0.00012 21.1 1.5 0.00062 18.8 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KOS13034.1 - 0.00028 20.7 0.2 0.025 14.2 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS13034.1 - 0.009 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KOS13034.1 - 0.0091 15.0 0.0 0.023 13.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 KOS13034.1 - 0.037 14.5 0.2 0.081 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KOS13034.1 - 0.051 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CoA_trans PF01144.18 KOS13035.1 - 4e-101 336.7 3.0 7.4e-68 227.9 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DeoRC PF00455.17 KOS13035.1 - 0.031 13.9 0.1 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 DeoR C terminal sensor domain Pkinase PF00069.20 KOS13036.1 - 4.2e-64 216.2 0.0 5.8e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13036.1 - 3.4e-29 101.7 0.0 4.8e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13036.1 - 8.1e-07 28.2 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13036.1 - 0.016 14.9 0.2 1.3 8.6 0.0 2.6 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KOS13036.1 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_25 PF13481.1 KOS13037.1 - 0.0002 20.8 2.3 0.0021 17.5 1.6 2.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KOS13037.1 - 0.00091 18.4 0.0 0.0027 16.8 0.0 1.9 1 1 0 1 1 1 1 KaiC AAA_28 PF13521.1 KOS13037.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KOS13037.1 - 0.0088 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KOS13037.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KOS13037.1 - 0.14 11.7 0.2 0.47 10.0 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Nramp PF01566.13 KOS13038.1 - 2.9e-87 292.7 22.5 3.7e-86 289.1 15.6 2.1 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein LRR19-TM PF15176.1 KOS13038.1 - 0.96 9.1 2.8 27 4.5 0.2 2.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain BATS PF06968.8 KOS13039.1 - 1.1e-25 89.3 0.0 2.3e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KOS13039.1 - 4.8e-16 59.3 0.1 8.9e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_hydro_63 PF03200.11 KOS13040.1 - 3.6e-221 736.2 7.0 6.2e-220 732.1 4.9 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KOS13040.1 - 2.5e-07 29.7 1.9 3.3e-07 29.3 1.3 1.3 1 0 0 1 1 1 1 Trehalase HMGL-like PF00682.14 KOS13041.1 - 1.3e-61 208.2 0.0 1.9e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KOS13041.1 - 2.7e-19 69.2 0.4 8.8e-18 64.3 0.3 2.4 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain LRR_9 PF14580.1 KOS13042.1 - 1.1e-49 168.3 0.3 1.5e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KOS13042.1 - 4.3e-15 55.2 8.3 4.7e-08 32.6 1.2 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KOS13042.1 - 1.3e-14 53.3 7.0 7.9e-07 28.5 0.5 3.8 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KOS13042.1 - 0.0017 18.2 0.4 32 5.0 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 KOS13042.1 - 0.0022 17.7 3.7 13 6.3 0.1 5.4 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KOS13042.1 - 0.0095 15.9 2.7 7.1 7.3 0.0 4.9 4 1 1 5 5 5 1 Leucine rich repeat TRAPPC10 PF12584.3 KOS13043.1 - 1e-18 67.2 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 HrpB1_HrpK PF09613.5 KOS13043.1 - 0.0022 17.5 1.0 0.085 12.3 0.1 2.6 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.1 KOS13043.1 - 0.0022 18.6 1.0 0.011 16.3 0.7 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Mem_trans PF03547.13 KOS13044.1 - 7.6e-35 119.9 2.9 2.4e-34 118.3 2.0 1.7 1 1 0 1 1 1 1 Membrane transport protein Nucleoside_tran PF01733.13 KOS13045.1 - 2.1e-11 43.5 6.6 2.1e-11 43.5 4.6 3.9 2 2 0 3 3 3 1 Nucleoside transporter GCD14 PF08704.5 KOS13046.1 - 8.8e-79 264.4 0.7 1.1e-44 152.8 0.2 3.1 3 0 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KOS13046.1 - 1.3e-06 28.4 0.2 2.4e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS13046.1 - 6.9e-05 23.3 0.0 0.071 13.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.1 KOS13046.1 - 0.0014 19.4 0.2 0.0038 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS13046.1 - 0.017 14.7 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 KOS13046.1 - 0.03 13.8 0.0 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bud13 PF09736.4 KOS13046.1 - 0.44 10.8 3.7 0.68 10.1 2.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Abhydrolase_3 PF07859.8 KOS13047.1 - 3.7e-18 65.8 0.0 1.6e-17 63.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS13047.1 - 4e-13 48.7 0.0 7e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Med7 PF05983.6 KOS13048.1 - 3.1e-33 114.8 0.0 9e-33 113.3 0.0 1.6 1 1 0 1 1 1 1 MED7 protein Peptidase_M23 PF01551.17 KOS13049.1 - 0.0017 18.3 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M23 Ribosom_S12_S23 PF00164.20 KOS13050.1 - 7.1e-48 161.0 0.3 9.5e-48 160.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DPBB_1 PF03330.13 KOS13051.1 - 0.00065 19.6 0.2 0.003 17.5 0.1 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KOS13051.1 - 0.00091 18.8 0.5 0.0011 18.5 0.4 1.3 1 1 0 1 1 1 1 Barwin family VIT1 PF01988.14 KOS13051.1 - 0.0074 15.7 0.4 0.0093 15.4 0.3 1.1 1 0 0 1 1 1 1 VIT family MRP-L20 PF12824.2 KOS13052.1 - 1.3e-31 109.8 4.8 3.2e-31 108.4 3.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 KOS13052.1 - 1.8e-07 31.2 0.0 7.9e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS13052.1 - 5e-06 26.3 0.0 0.016 14.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KOS13052.1 - 0.0018 17.2 0.4 0.043 12.7 0.1 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KOS13052.1 - 0.0027 16.7 0.0 1.3 8.0 0.0 3.3 5 0 0 5 5 5 2 FAD binding domain Pyr_redox_3 PF13738.1 KOS13052.1 - 0.0041 17.2 0.1 0.22 11.5 0.0 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KOS13052.1 - 0.012 14.5 0.5 2.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HTH_11 PF08279.7 KOS13052.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain FAD_binding_2 PF00890.19 KOS13052.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KOS13052.1 - 0.15 12.4 0.2 3 8.2 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FKBP_C PF00254.23 KOS13054.1 - 7.3e-32 109.2 0.0 8.4e-32 109.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_M48 PF01435.13 KOS13055.1 - 7.4e-33 113.9 0.0 1.5e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 Adap_comp_sub PF00928.16 KOS13056.1 - 2.8e-24 85.6 0.0 4.1e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS13056.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Arm PF00514.18 KOS13058.1 - 0.00046 19.9 0.1 0.00046 19.9 0.1 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KOS13058.1 - 0.024 14.6 5.2 0.59 10.3 0.0 4.5 3 0 0 3 3 3 0 HEAT repeat Ribosomal_S15 PF00312.17 KOS13059.1 - 8e-17 60.7 1.1 9.8e-17 60.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 HTH_39 PF14090.1 KOS13059.1 - 0.06 12.8 0.1 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain FAD-SLDH PF12318.3 KOS13059.1 - 0.22 11.2 1.5 0.81 9.3 0.1 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Pex19 PF04614.7 KOS13061.1 - 1.8e-52 178.4 15.0 1.8e-52 178.4 10.4 2.0 1 1 1 2 2 2 1 Pex19 protein family DUF1825 PF08855.5 KOS13061.1 - 0.0025 17.7 1.8 0.011 15.7 0.0 2.9 2 1 2 4 4 4 1 Domain of unknown function (DUF1825) FlaG PF03646.10 KOS13061.1 - 0.083 13.0 0.7 0.083 13.0 0.5 2.8 2 1 1 3 3 3 0 FlaG protein Ribosomal_L1 PF00687.16 KOS13061.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family Apolipoprotein PF01442.13 KOS13061.1 - 0.69 9.3 5.7 0.71 9.3 0.1 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3486 PF11985.3 KOS13061.1 - 1.7 8.6 12.0 0.29 11.1 1.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3486) MSP1_C PF07462.6 KOS13061.1 - 2 6.7 4.2 3 6.1 2.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Herpes_capsid PF06112.6 KOS13061.1 - 3.5 7.6 9.8 23 5.0 5.3 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein TPR_16 PF13432.1 KOS13062.1 - 3.5e-12 46.6 10.8 0.00011 22.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13062.1 - 7.2e-09 34.8 21.4 0.0016 18.2 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13062.1 - 1.4e-08 34.5 15.4 0.014 15.9 0.0 5.0 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13062.1 - 2.9e-07 30.7 18.9 0.00014 22.1 2.1 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS13062.1 - 3.4e-06 26.6 13.5 0.0031 17.1 4.2 3.4 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 KOS13062.1 - 1.9e-05 24.5 10.9 0.53 10.6 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13062.1 - 1.9e-05 24.1 15.1 0.014 15.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13062.1 - 3.2e-05 24.1 14.1 0.0027 18.0 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13062.1 - 0.0013 18.2 13.3 0.097 12.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KOS13062.1 - 0.0026 17.8 11.5 0.0037 17.3 3.1 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KOS13062.1 - 0.0061 16.3 5.0 0.046 13.5 1.0 3.2 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KOS13062.1 - 0.008 16.1 1.9 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13062.1 - 0.011 15.4 8.8 0.64 9.9 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KOS13062.1 - 0.02 14.9 4.9 0.4 10.8 0.8 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KOS13062.1 - 0.038 13.0 8.9 0.097 11.7 4.9 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 KOS13062.1 - 0.1 11.3 4.9 0.11 11.1 0.1 2.1 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 KOS13062.1 - 0.3 11.0 20.3 0.28 11.1 1.0 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L6 PF00347.18 KOS13063.1 - 4.5e-22 78.3 0.5 3.8e-14 52.9 0.0 3.1 4 0 0 4 4 4 2 Ribosomal protein L6 NDUFA12 PF05071.11 KOS13064.1 - 2.4e-09 37.5 3.0 2.4e-09 37.5 2.1 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2293 PF10056.4 KOS13064.1 - 0.042 13.8 3.3 0.93 9.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) FUSC PF04632.7 KOS13064.1 - 2.2 6.5 6.9 2.6 6.3 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family rRNA_processing PF08524.6 KOS13065.1 - 2.4e-09 37.1 14.2 1.8e-08 34.2 9.8 2.1 1 1 0 1 1 1 1 rRNA processing eIF3_subunit PF08597.5 KOS13065.1 - 0.75 9.3 12.2 0.26 10.8 6.8 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit WD40 PF00400.27 KOS13066.1 - 3e-31 106.1 5.3 4e-07 29.6 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS13066.1 - 0.00061 19.5 0.0 0.36 10.5 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KOS13066.1 - 0.00086 18.9 0.3 0.44 10.2 0.1 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Npa1 PF11707.3 KOS13067.1 - 2.3e-62 210.9 0.0 5.1e-62 209.7 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal P5CR_dimer PF14748.1 KOS13068.1 - 7.4e-38 128.8 3.3 7.4e-38 128.8 2.3 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KOS13068.1 - 7.9e-13 48.6 1.8 5.5e-11 42.7 0.3 2.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyoxalase_5 PF14696.1 KOS13068.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal p450 PF00067.17 KOS13069.1 - 1.9e-59 201.3 0.0 3.2e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YqeY PF09424.5 KOS13069.1 - 2.9e-12 46.6 1.1 6.5e-12 45.5 0.7 1.6 1 0 0 1 1 1 1 Yqey-like protein Abhydrolase_2 PF02230.11 KOS13070.1 - 3.8e-54 183.3 0.0 4.3e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KOS13070.1 - 1.7e-12 47.3 0.1 2.6e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS13070.1 - 8.2e-10 38.9 1.0 1.4e-09 38.2 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS13070.1 - 3.5e-05 23.3 0.0 8.6e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.7 KOS13070.1 - 0.0071 14.8 0.0 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KOS13070.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.15 KOS13070.1 - 0.014 14.8 1.3 0.04 13.3 0.9 1.9 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.4 KOS13070.1 - 0.046 12.9 0.6 0.21 10.8 0.1 2.1 2 1 1 3 3 3 0 Esterase PHB depolymerase Lipase_3 PF01764.20 KOS13070.1 - 0.086 12.4 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) LIP PF03583.9 KOS13070.1 - 0.095 11.8 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Cutinase PF01083.17 KOS13070.1 - 0.15 11.7 0.0 0.89 9.2 0.0 1.9 2 0 0 2 2 2 0 Cutinase Abhydrolase_6 PF12697.2 KOS13071.1 - 3e-07 30.5 1.4 7.2e-07 29.3 0.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1500 PF07389.7 KOS13071.1 - 0.076 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) ATP_bind_1 PF03029.12 KOS13072.1 - 4.9e-81 271.7 0.1 5.6e-81 271.5 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KOS13072.1 - 2.2e-06 28.5 0.1 4.6e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS13072.1 - 0.00055 20.0 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KOS13072.1 - 0.00067 18.5 0.0 0.00097 17.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KOS13072.1 - 0.00077 18.9 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 KOS13072.1 - 0.0013 18.4 0.0 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KOS13072.1 - 0.0015 18.2 0.0 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KOS13072.1 - 0.0017 17.8 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 KOS13072.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KOS13072.1 - 0.0027 17.1 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS13072.1 - 0.0056 15.8 0.1 0.71 8.9 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KOS13072.1 - 0.0059 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.1 KOS13072.1 - 0.006 16.0 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KOS13072.1 - 0.0078 16.5 0.1 0.023 15.0 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KOS13072.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KOS13072.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 KOS13072.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.5 2 0 0 2 2 1 0 NTPase MMR_HSR1 PF01926.18 KOS13072.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KOS13072.1 - 0.024 14.5 0.0 0.062 13.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KOS13072.1 - 0.03 14.5 0.0 0.09 12.9 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS13072.1 - 0.046 13.1 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain MipZ PF09140.6 KOS13072.1 - 0.047 12.7 0.1 0.89 8.5 0.0 2.5 2 1 0 2 2 2 0 ATPase MipZ T2SE PF00437.15 KOS13072.1 - 0.053 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KOS13072.1 - 0.056 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS13072.1 - 0.057 13.6 0.0 0.25 11.5 0.0 2.1 2 1 0 2 2 2 0 RNA helicase NACHT PF05729.7 KOS13072.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KOS13072.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 KOS13072.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 KOS13072.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 KOS13072.1 - 0.15 11.4 0.1 2.8 7.3 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ETF_QO PF05187.8 KOS13073.1 - 6.4e-42 142.0 0.0 1.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 KOS13073.1 - 1.4e-07 30.7 4.2 0.00055 18.8 2.6 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 KOS13073.1 - 5.7e-07 28.7 1.2 0.00084 18.3 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS13073.1 - 1.1e-05 25.2 0.1 3.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KOS13073.1 - 1.3e-05 24.4 0.1 0.0002 20.5 0.3 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KOS13073.1 - 6e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS13073.1 - 0.00046 20.3 0.2 0.00079 19.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS13073.1 - 0.00058 18.4 2.4 0.00084 17.9 1.7 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KOS13073.1 - 0.00082 18.5 0.5 0.0014 17.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 KOS13073.1 - 0.00098 19.4 5.8 0.0022 18.3 4.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KOS13073.1 - 0.0013 18.5 2.4 0.0027 17.5 1.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.2 KOS13073.1 - 0.0021 17.1 0.1 0.0028 16.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4 PF00037.22 KOS13073.1 - 0.0026 17.2 1.3 0.0026 17.2 0.9 1.8 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_2 PF12797.2 KOS13073.1 - 0.0028 17.4 2.1 0.0074 16.1 1.5 1.8 1 0 0 1 1 1 1 4Fe-4S binding domain Lycopene_cycl PF05834.7 KOS13073.1 - 0.0047 15.8 0.2 0.0072 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_10 PF13237.1 KOS13073.1 - 0.0052 16.5 4.5 0.013 15.3 3.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.1 KOS13073.1 - 0.0071 16.1 0.4 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_6 PF12837.2 KOS13073.1 - 0.0098 15.7 2.2 0.0098 15.7 1.5 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain DUF4147 PF13660.1 KOS13073.1 - 0.02 14.0 0.2 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Fer4_9 PF13187.1 KOS13073.1 - 0.034 14.4 5.9 0.07 13.4 4.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 KOS13073.1 - 0.081 12.9 4.1 0.17 11.9 2.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 KOS13073.1 - 0.14 11.0 1.0 0.2 10.4 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_4 PF12800.2 KOS13073.1 - 0.15 12.4 4.8 0.41 11.1 3.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Pyr_redox PF00070.22 KOS13073.1 - 0.22 11.9 1.3 6.5 7.2 0.6 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.1 KOS13073.1 - 0.3 11.4 4.1 0.67 10.3 2.9 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.9 KOS13073.1 - 0.45 9.0 1.3 0.77 8.3 0.9 1.3 1 0 0 1 1 1 0 Tryptophan halogenase B3_4 PF03483.12 KOS13074.1 - 1.3e-25 89.8 0.1 2e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KOS13074.1 - 2.5e-17 62.4 0.0 4.3e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain Proteasome PF00227.21 KOS13075.1 - 3e-36 124.4 0.0 3.6e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cwf_Cwc_15 PF04889.7 KOS13076.1 - 1.8e-57 194.8 24.1 2e-57 194.7 16.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein AnfO_nitrog PF09582.5 KOS13076.1 - 0.056 12.5 1.1 0.11 11.5 0.8 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Prp19_bind PF06991.6 KOS13076.1 - 0.074 12.3 24.2 0.47 9.6 10.9 2.2 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain MaoC_dehydrat_N PF13452.1 KOS13076.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Daxx PF03344.10 KOS13076.1 - 3 6.2 23.5 3.6 5.9 16.3 1.2 1 0 0 1 1 1 0 Daxx Family Nop53 PF07767.6 KOS13076.1 - 3.5 6.5 26.1 5.6 5.8 18.1 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GED PF02212.13 KOS13076.1 - 3.9 7.4 6.9 10 6.0 4.8 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain CDC45 PF02724.9 KOS13076.1 - 5.2 4.9 20.7 7 4.5 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 KOS13077.1 - 3.4e-70 236.1 0.0 4.1e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13077.1 - 3.1e-28 98.5 0.0 4.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_4 PF15404.1 KOS13078.1 - 2.1e-21 76.3 0.3 2.9e-19 69.3 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KOS13078.1 - 0.0027 17.8 0.0 1.8 8.7 0.0 3.4 3 1 0 3 3 3 2 PH domain Radial_spoke PF04712.7 KOS13078.1 - 0.13 10.9 0.2 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein NTF2 PF02136.15 KOS13079.1 - 3e-32 111.4 0.3 3.4e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Glyoxalase PF00903.20 KOS13080.1 - 6.7e-21 74.5 0.1 8.2e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KOS13080.1 - 3.8e-18 66.0 0.0 4.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KOS13080.1 - 7.5e-08 32.3 0.0 1.2e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KOS13080.1 - 0.0089 15.9 0.0 0.035 13.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Hexokinase_2 PF03727.11 KOS13081.1 - 6e-77 258.1 0.0 1.2e-76 257.1 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KOS13081.1 - 7.2e-69 231.2 0.0 1.5e-68 230.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Tox-PL-2 PF15643.1 KOS13081.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 2 Pept_tRNA_hydro PF01195.14 KOS13082.1 - 6.7e-25 87.6 0.0 1.4e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase HECT_2 PF09814.4 KOS13083.1 - 1.1e-12 47.3 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GST_N_3 PF13417.1 KOS13084.1 - 9.4e-08 32.1 0.1 2.5e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS13084.1 - 2.7e-06 27.2 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS13084.1 - 0.00065 19.5 0.1 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KOS13084.1 - 0.0075 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS13084.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GIY-YIG PF01541.19 KOS13085.1 - 9.6e-06 25.8 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Dynamitin PF04912.9 KOS13086.1 - 1.2e-23 83.6 12.6 1.2e-22 80.3 8.7 2.0 1 1 0 1 1 1 1 Dynamitin DUF4047 PF13256.1 KOS13086.1 - 0.052 13.5 0.2 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Mating_N PF12731.2 KOS13086.1 - 0.24 11.3 11.0 6.5 6.7 0.4 4.5 5 0 0 5 5 5 0 Mating-type protein beta 1 DUF342 PF03961.8 KOS13086.1 - 0.26 9.6 0.9 0.82 8.0 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 KOS13086.1 - 2 8.2 10.2 3.3 7.5 0.1 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fmp27_WPPW PF10359.4 KOS13086.1 - 2.4 6.4 6.5 1.4 7.2 0.3 2.5 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain FlgN PF05130.7 KOS13086.1 - 2.7 8.2 24.0 3.2 7.9 10.8 3.3 1 1 1 3 3 3 0 FlgN protein DUF2721 PF11026.3 KOS13086.1 - 3.5 7.2 6.5 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) SpaB_C PF14028.1 KOS13086.1 - 6.6 6.1 16.2 1.1 8.7 6.8 2.0 1 1 1 2 2 2 0 SpaB C-terminal domain SMI1_KNR4 PF09346.5 KOS13087.1 - 9e-18 64.5 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SHQ1 PF04925.10 KOS13088.1 - 2.3e-27 95.6 0.7 6.2e-27 94.2 0.5 1.7 1 1 0 1 1 1 1 SHQ1 protein TBCA PF02970.11 KOS13089.1 - 0.022 14.8 0.4 0.059 13.4 0.3 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A AATF-Che1 PF13339.1 KOS13089.1 - 9 6.4 7.7 1.9 8.6 1.6 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor SET PF00856.23 KOS13090.1 - 2.1e-06 28.1 0.0 1.3e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KOS13090.1 - 0.00011 22.0 0.0 0.0026 17.6 0.0 2.4 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Cep57_MT_bd PF06657.8 KOS13091.1 - 4.9e-10 39.2 2.6 4.9e-10 39.2 1.8 3.6 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 KOS13091.1 - 0.072 12.6 11.2 0.32 10.5 0.5 3.3 3 1 0 3 3 3 0 IncA protein FlxA PF14282.1 KOS13091.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.4 3 0 0 3 3 3 0 FlxA-like protein CENP-Q PF13094.1 KOS13091.1 - 0.52 10.3 16.8 0.037 14.0 1.9 3.6 1 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1515 PF07439.6 KOS13091.1 - 0.64 9.8 3.1 0.45 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) YlqD PF11068.3 KOS13091.1 - 5.4 7.0 8.1 5.6 7.0 0.3 2.6 3 0 0 3 3 3 0 YlqD protein RRM_1 PF00076.17 KOS13092.1 - 2.2e-09 36.8 0.1 9.6e-07 28.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13092.1 - 3.3e-08 33.3 0.0 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13092.1 - 0.0028 17.4 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.11 KOS13093.1 - 6.6e-05 22.4 0.0 0.00024 20.5 0.0 2.0 1 1 0 1 1 1 1 GYF domain EF-hand_7 PF13499.1 KOS13094.1 - 2.2e-09 37.3 2.4 7.2e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS13094.1 - 2.8e-08 32.9 0.1 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KOS13094.1 - 6.2e-07 28.2 0.0 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 KOS13094.1 - 3.6e-06 26.0 0.0 0.00042 19.5 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KOS13094.1 - 0.0015 18.0 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair zf-NPL4 PF05020.10 KOS13094.1 - 0.11 12.1 0.6 0.22 11.1 0.4 1.6 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region RPAP1_C PF08620.5 KOS13095.1 - 8.5e-23 80.0 0.1 2e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal HEAT PF02985.17 KOS13095.1 - 0.0012 18.7 2.7 3.6 7.9 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat RPAP1_N PF08621.5 KOS13095.1 - 0.039 13.5 0.4 0.084 12.4 0.2 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal CBF PF03914.12 KOS13096.1 - 3.8e-35 120.7 0.0 8.6e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 CBF/Mak21 family SPT6_acidic PF14632.1 KOS13096.1 - 0.39 10.9 6.4 0.99 9.6 4.4 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PBP1_TM PF14812.1 KOS13096.1 - 1.4 9.2 4.1 3.9 7.8 2.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Formyl_trans_N PF00551.14 KOS13097.1 - 1.1e-33 116.3 0.0 2.8e-31 108.4 0.0 2.3 1 1 0 1 1 1 1 Formyl transferase TFIID_20kDa PF03847.8 KOS13098.1 - 2e-33 114.4 0.4 3.9e-33 113.5 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KOS13098.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS13098.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Pyr_redox_2 PF07992.9 KOS13099.1 - 1.5e-88 295.9 5.0 4.6e-44 150.7 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KOS13099.1 - 1.4e-64 214.9 4.3 3.1e-32 110.8 0.2 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KOS13099.1 - 6.3e-43 145.0 16.2 3.9e-19 68.8 0.0 5.3 5 0 0 5 5 5 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS13099.1 - 1.8e-28 100.0 2.6 5.6e-10 39.6 0.0 4.8 4 1 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KOS13099.1 - 1.7e-15 57.0 1.7 4.5e-07 29.2 0.1 2.8 4 0 0 4 4 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KOS13099.1 - 4.9e-14 51.6 12.8 0.0062 15.0 1.3 5.9 6 0 0 6 6 6 4 HI0933-like protein K_oxygenase PF13434.1 KOS13099.1 - 8.4e-11 41.3 0.1 0.00018 20.5 0.0 3.2 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KOS13099.1 - 6.5e-10 38.4 18.0 0.00076 18.4 0.2 5.9 6 0 0 6 6 6 2 FAD binding domain Thi4 PF01946.12 KOS13099.1 - 1.4e-08 34.1 3.3 0.0016 17.5 0.2 2.5 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.1 KOS13099.1 - 1.6e-07 31.4 0.7 0.62 10.3 0.0 4.6 5 0 0 5 5 4 2 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KOS13099.1 - 4.3e-06 26.6 15.7 0.0054 16.7 2.6 3.1 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KOS13099.1 - 3.5e-05 22.8 15.0 0.011 14.6 0.4 3.9 4 1 0 4 4 4 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KOS13099.1 - 0.0002 20.9 2.1 7.1 6.1 0.1 4.5 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KOS13099.1 - 0.00025 20.0 15.7 0.0056 15.6 0.3 4.2 6 0 0 6 6 6 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KOS13099.1 - 0.0021 17.2 3.4 6.7 5.8 0.0 4.0 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MDMPI_C PF07398.6 KOS13099.1 - 0.0073 16.8 0.3 9.3 6.9 0.0 3.2 2 0 0 2 2 2 0 MDMPI C-terminal domain CPSase_L_chain PF00289.17 KOS13099.1 - 0.0081 16.2 1.1 7.5 6.7 0.0 3.5 4 0 0 4 4 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain 3HCDH_N PF02737.13 KOS13099.1 - 0.011 15.3 15.7 0.34 10.5 0.0 4.6 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KOS13099.1 - 0.016 14.1 3.6 3.3 6.5 0.4 3.3 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KOS13099.1 - 0.037 13.4 0.1 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 KOS13099.1 - 0.047 14.0 0.7 21 5.4 0.0 3.7 4 0 0 4 4 4 0 XdhC Rossmann domain Spermine_synth PF01564.12 KOS13099.1 - 0.22 10.4 1.4 7.2 5.4 0.0 2.8 3 0 0 3 3 3 0 Spermine/spermidine synthase NAD_Gly3P_dh_N PF01210.18 KOS13099.1 - 2 8.0 7.6 4 7.1 0.0 3.4 4 0 0 4 4 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 KOS13099.1 - 3 6.7 17.9 1.4 7.8 0.1 3.8 4 0 0 4 4 3 0 FAD binding domain ABC_membrane PF00664.18 KOS13100.1 - 1.1e-99 333.3 33.2 2.8e-56 190.9 10.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS13100.1 - 2.5e-70 235.0 0.0 6.5e-34 117.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KOS13100.1 - 2.2e-14 53.2 1.7 0.00021 20.6 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS13100.1 - 1.5e-12 48.0 0.1 0.012 15.5 0.0 4.5 5 0 0 5 5 4 3 AAA domain ABC_ATPase PF09818.4 KOS13100.1 - 2.6e-09 36.1 0.7 0.0015 17.1 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KOS13100.1 - 3.7e-09 35.9 1.3 0.00037 19.9 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS13100.1 - 1.4e-07 31.6 2.9 0.0057 16.6 0.2 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KOS13100.1 - 2e-07 31.8 0.0 0.029 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KOS13100.1 - 4.4e-07 30.1 1.6 0.028 14.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KOS13100.1 - 2.5e-06 26.7 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KOS13100.1 - 5.7e-06 26.0 0.2 0.64 9.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 KOS13100.1 - 7.2e-06 26.2 1.1 0.38 10.9 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS13100.1 - 1.9e-05 24.4 0.2 0.35 10.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KOS13100.1 - 2.1e-05 24.9 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KOS13100.1 - 2.4e-05 24.1 2.5 0.35 10.8 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KOS13100.1 - 0.00015 21.3 0.1 0.22 10.9 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 KOS13100.1 - 0.00019 21.7 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KOS13100.1 - 0.00019 20.9 0.1 0.35 10.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KOS13100.1 - 0.00019 21.1 0.1 0.96 9.2 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 KOS13100.1 - 0.00025 20.1 0.0 0.075 12.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KOS13100.1 - 0.00034 20.5 0.0 1.4 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 KOS13100.1 - 0.0015 17.2 0.0 0.17 10.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF87 PF01935.12 KOS13100.1 - 0.0016 18.2 0.0 0.18 11.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KOS13100.1 - 0.0033 17.1 0.1 3.5 7.3 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KOS13100.1 - 0.0034 17.5 0.1 3.9 7.7 0.0 3.8 4 0 0 4 4 4 1 RNA helicase AAA_14 PF13173.1 KOS13100.1 - 0.0039 17.1 0.0 1.9 8.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain APS_kinase PF01583.15 KOS13100.1 - 0.014 15.0 0.0 4.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 KOS13100.1 - 0.024 14.1 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KOS13100.1 - 0.024 14.5 0.2 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KOS13100.1 - 0.026 14.4 0.1 9.3 6.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 KOS13100.1 - 0.03 13.2 0.0 0.79 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 KOS13100.1 - 0.036 12.7 0.0 7.6 5.1 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 KOS13100.1 - 0.12 11.2 0.0 7.9 5.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PI3_PI4_kinase PF00454.22 KOS13101.1 - 1.1e-49 169.0 0.0 2e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KOS13101.1 - 4.7e-24 85.0 1.2 1.2e-23 83.7 0.8 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KOS13101.1 - 2.7e-18 65.8 0.0 1.2e-17 63.7 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KOS13101.1 - 1.6e-08 33.7 0.0 4.3e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 KOS13101.1 - 1.3e-05 24.7 1.2 0.54 9.9 0.0 4.2 3 1 2 5 5 5 3 TPR repeat DUF3385 PF11865.3 KOS13101.1 - 0.078 12.9 0.4 0.58 10.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Ribosomal_L23eN PF03939.8 KOS13102.1 - 9.2e-21 73.6 7.9 9.2e-21 73.6 5.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KOS13102.1 - 1.6e-18 66.4 1.8 4.2e-18 65.0 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 Med6 PF04934.9 KOS13103.1 - 5.5e-38 129.6 0.0 7.6e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component ABM PF03992.11 KOS13103.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF4464 PF14713.1 KOS13103.1 - 0.1 12.0 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) DUF572 PF04502.8 KOS13104.1 - 3.7e-80 269.5 9.8 4.5e-80 269.3 6.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 KOS13104.1 - 0.0057 16.2 0.9 0.6 9.7 0.1 2.3 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif C1_3 PF07649.7 KOS13104.1 - 0.027 14.5 3.1 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 C1-like domain Lar_restr_allev PF14354.1 KOS13104.1 - 0.036 14.3 0.8 2.3 8.5 1.2 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF866 PF05907.8 KOS13104.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) RRN7 PF11781.3 KOS13104.1 - 0.13 11.7 0.6 9.9 5.7 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TB2_DP1_HVA22 PF03134.14 KOS13105.1 - 1.6e-20 72.6 10.5 2.7e-18 65.4 4.8 2.2 2 0 0 2 2 2 2 TB2/DP1, HVA22 family SRP14 PF02290.10 KOS13106.1 - 7.9e-15 54.5 0.3 1.8e-13 50.2 0.2 2.6 1 1 0 1 1 1 1 Signal recognition particle 14kD protein zf-CCHC PF00098.18 KOS13107.1 - 1.4e-11 43.6 12.6 1.2e-06 28.1 0.9 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KOS13107.1 - 4.2e-07 29.5 12.2 0.00014 21.5 3.1 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KOS13107.1 - 2.8e-06 26.8 0.5 5.1e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KOS13107.1 - 3.1e-05 23.4 0.1 6.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 KH domain DUF1897 PF09005.5 KOS13107.1 - 0.00011 21.5 31.8 0.0048 16.3 9.4 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF1897) zf-CCHC_2 PF13696.1 KOS13107.1 - 0.011 15.2 1.5 0.011 15.2 1.0 3.3 4 0 0 4 4 3 0 Zinc knuckle PolC_DP2 PF03833.8 KOS13107.1 - 0.11 10.0 1.8 0.16 9.5 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CCHC_5 PF14787.1 KOS13107.1 - 0.28 10.7 9.4 0.093 12.2 1.4 2.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 KOS13107.1 - 0.96 9.1 8.3 5.8 6.6 0.4 2.8 1 1 1 2 2 2 0 Zinc knuckle DZR PF12773.2 KOS13107.1 - 1.5 8.7 6.5 3.9 7.3 4.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_4 PF14392.1 KOS13107.1 - 5.1 6.8 11.6 6.3 6.5 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-DHHC PF01529.15 KOS13108.1 - 8.5e-34 116.4 8.7 1.8e-33 115.3 6.0 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase adh_short PF00106.20 KOS13109.1 - 8e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS13109.1 - 3.7e-09 36.7 0.0 5.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS13109.1 - 2.8e-08 33.6 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS13109.1 - 4.7e-05 22.9 0.0 6.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS13109.1 - 0.0021 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KOS13109.1 - 0.039 12.8 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 KOS13109.1 - 0.074 13.1 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SMC_hinge PF06470.8 KOS13109.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain DUF4131 PF13567.1 KOS13110.1 - 0.013 14.8 2.4 0.017 14.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4010 PF13194.1 KOS13110.1 - 0.061 12.6 2.5 0.087 12.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Apq12 PF12716.2 KOS13110.1 - 0.34 10.6 12.8 0.65 9.7 8.8 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF1180 PF06679.7 KOS13110.1 - 0.39 10.5 3.5 0.2 11.5 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) GYF PF02213.11 KOS13111.1 - 2.3e-12 46.2 0.1 4.9e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 GYF domain RRP7 PF12923.2 KOS13111.1 - 0.11 12.4 2.7 3.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) WD40 PF00400.27 KOS13113.1 - 5.8e-12 45.0 8.6 0.00025 20.8 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KOS13113.1 - 0.011 16.0 3.3 43 4.5 0.0 5.3 5 1 0 5 5 5 0 PQQ-like domain TRAM_LAG1_CLN8 PF03798.11 KOS13114.1 - 8.7e-31 107.0 18.7 8.7e-31 107.0 12.9 1.7 2 0 0 2 2 2 1 TLC domain GCIP PF13324.1 KOS13115.1 - 1.5e-06 27.6 1.2 5.4e-06 25.8 0.3 2.3 2 1 1 3 3 3 1 Grap2 and cyclin-D-interacting Dynamin_N PF00350.18 KOS13116.1 - 9.4e-18 64.5 0.0 2.5e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KOS13116.1 - 2.7e-10 40.2 0.0 3.7e-09 36.5 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS13116.1 - 8.1e-09 35.1 0.7 1.3e-07 31.2 0.5 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KOS13116.1 - 7.6e-06 26.4 0.1 0.0056 17.1 0.0 2.8 1 1 1 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KOS13116.1 - 2.6e-05 23.6 0.0 0.0046 16.4 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain cobW PF02492.14 KOS13116.1 - 0.00057 19.3 0.7 0.0048 16.3 0.5 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 KOS13116.1 - 0.0017 17.5 3.8 4.8 6.3 0.0 4.3 2 1 1 3 3 3 2 ADP-ribosylation factor family FeoB_N PF02421.13 KOS13116.1 - 0.0028 16.9 0.4 4.5 6.5 0.0 3.2 3 0 0 3 3 3 2 Ferrous iron transport protein B IIGP PF05049.8 KOS13116.1 - 0.0048 15.7 0.2 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KOS13116.1 - 0.036 13.5 0.8 1.3 8.4 0.0 3.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family Septin PF00735.13 KOS13116.1 - 0.036 13.0 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_18 PF13238.1 KOS13116.1 - 0.051 13.8 0.1 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KOS13116.1 - 0.053 13.0 0.0 7.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PglZ PF08665.7 KOS13116.1 - 0.42 10.2 5.5 0.82 9.3 0.1 3.1 2 1 0 3 3 3 0 PglZ domain Ribosomal_S8e PF01201.17 KOS13117.1 - 2.4e-49 166.8 1.1 2.9e-49 166.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e ATP-synt_C PF00137.16 KOS13118.1 - 1.6e-28 98.4 27.2 1e-16 60.5 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxysterol_BP PF01237.13 KOS13119.1 - 3.6e-117 390.8 0.0 4.7e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KOS13119.1 - 2.2e-07 30.8 0.1 8.3e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KOS13119.1 - 0.0059 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KOS13119.1 - 0.1 12.8 0.2 0.36 11.0 0.1 1.9 1 1 0 1 1 1 0 PH domain DUF883 PF05957.8 KOS13119.1 - 0.42 11.0 3.3 22 5.5 0.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Herpes_LMP1 PF05297.6 KOS13119.1 - 6.9 5.4 6.9 10 4.9 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PAP_central PF04928.12 KOS13120.1 - 1.3e-106 355.0 0.0 1.7e-106 354.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KOS13120.1 - 4.7e-44 149.6 0.0 7.5e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KOS13120.1 - 9.7e-09 35.4 0.0 2.5e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_M16 PF00675.15 KOS13121.1 - 3.3e-54 182.6 1.1 3.3e-53 179.4 0.5 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS13121.1 - 4.2e-43 147.1 0.0 5.7e-40 136.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain B5 PF03484.10 KOS13121.1 - 0.083 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetase B5 domain Oxysterol_BP PF01237.13 KOS13122.1 - 2e-85 286.4 0.1 2.4e-85 286.1 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 KOS13122.1 - 0.032 14.6 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Kinesin motor Aconitase PF00330.15 KOS13123.1 - 2e-179 596.9 0.0 2.4e-179 596.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS13123.1 - 9.3e-42 142.2 0.0 1.7e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TFIID-18kDa PF02269.11 KOS13124.1 - 1.1e-14 54.0 0.8 1.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Transcription initiation factor IID, 18kD subunit Peptidase_M35 PF02102.10 KOS13125.1 - 0.087 11.4 0.4 0.12 10.9 0.3 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Tmemb_9 PF05434.6 KOS13125.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM9 SurE PF01975.12 KOS13126.1 - 4.3e-33 114.2 0.0 7.2e-33 113.5 0.0 1.3 1 1 0 1 1 1 1 Survival protein SurE WEMBL PF05701.6 KOS13127.1 - 0.00024 19.6 31.4 0.047 12.1 21.6 2.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light DUF869 PF05911.6 KOS13127.1 - 0.00099 17.4 22.7 0.0018 16.6 15.7 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Filament PF00038.16 KOS13127.1 - 0.001 18.6 25.3 0.23 10.9 6.7 3.0 1 1 0 1 1 1 1 Intermediate filament protein APG6 PF04111.7 KOS13127.1 - 0.027 13.5 31.5 0.27 10.2 14.5 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KOS13127.1 - 0.032 11.9 27.1 0.06 11.0 18.8 1.4 1 0 0 1 1 1 0 Myosin tail DUF2353 PF09789.4 KOS13127.1 - 0.069 12.4 23.6 0.094 11.9 2.0 3.4 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) Fib_alpha PF08702.5 KOS13127.1 - 0.084 12.9 15.8 0.17 12.0 8.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KOS13127.1 - 0.12 12.1 36.1 0.7 9.6 10.6 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.6 KOS13127.1 - 0.13 12.0 40.4 0.039 13.8 20.7 3.0 2 1 1 3 3 3 0 Rabaptin-like protein Reo_sigmaC PF04582.7 KOS13127.1 - 0.49 9.5 21.1 0.012 14.7 3.4 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KOS13127.1 - 0.51 8.7 20.0 1.2 7.4 13.3 1.8 1 1 2 3 3 3 0 AAA domain Ubiquitin_3 PF14836.1 KOS13127.1 - 0.54 9.9 5.7 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain GAS PF13851.1 KOS13127.1 - 0.55 9.4 25.7 0.89 8.7 5.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 KOS13127.1 - 0.56 10.1 26.9 0.71 9.8 9.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin PF00261.15 KOS13127.1 - 1.1 8.3 26.4 0.054 12.5 7.9 2.3 1 1 1 2 2 2 0 Tropomyosin IncA PF04156.9 KOS13127.1 - 1.7 8.2 38.5 1.5 8.3 16.3 2.4 1 1 1 2 2 2 0 IncA protein Mod_r PF07200.8 KOS13127.1 - 2.8 7.8 26.1 6.7 6.6 7.2 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF342 PF03961.8 KOS13127.1 - 6.3 5.0 14.4 1.6 7.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KOS13127.1 - 8.5 6.5 16.7 0.48 10.6 1.3 3.7 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HA2 PF04408.18 KOS13128.1 - 2.8e-30 104.3 0.0 5.6e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS13128.1 - 3.2e-25 88.1 0.0 7.4e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS13128.1 - 5.1e-11 42.2 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS13128.1 - 1.5e-07 31.1 0.1 3.2e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS13128.1 - 1.1e-05 25.5 0.0 2.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KOS13128.1 - 0.0025 17.5 0.2 0.0059 16.3 0.2 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KOS13128.1 - 0.0028 17.5 0.1 0.38 10.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KOS13128.1 - 0.0093 14.8 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KOS13128.1 - 0.05 13.0 1.0 0.38 10.1 0.7 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KOS13128.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyt-b5 PF00173.23 KOS13129.1 - 9.2e-27 92.6 0.1 1e-26 92.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NOC3p PF07540.6 KOS13129.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Nucleolar complex-associated protein PI3_PI4_kinase PF00454.22 KOS13130.1 - 2.8e-44 151.3 0.0 3.2e-42 144.6 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KOS13130.1 - 4e-43 146.7 0.8 6.1e-43 146.1 0.6 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KOS13130.1 - 1.2e-32 112.6 0.0 2e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Amino_oxidase PF01593.19 KOS13131.1 - 2.9e-14 53.0 0.0 1.6e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS13131.1 - 2.3e-09 37.1 0.3 4.5e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS13131.1 - 3.1e-05 24.1 0.1 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS13131.1 - 0.0014 18.4 0.0 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS13131.1 - 0.0036 17.1 0.2 0.6 9.8 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KOS13131.1 - 0.016 14.1 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Chs3p PF12271.3 KOS13132.1 - 1.1e-100 336.4 20.5 1.3e-100 336.1 14.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Chitin_synth_1 PF01644.12 KOS13133.1 - 6.9e-78 260.0 0.1 1.1e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KOS13133.1 - 2.4e-30 104.0 0.1 4.6e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KOS13133.1 - 7.1e-22 77.4 5.7 7.3e-19 67.5 0.5 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KOS13133.1 - 3.4e-08 33.5 0.1 1.2e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS13133.1 - 4.3e-06 26.5 15.7 5.9e-05 22.8 10.9 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 CTK3 PF12243.3 KOS13134.1 - 2.8e-34 117.7 0.1 4.2e-34 117.1 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KOS13134.1 - 1.1e-14 54.2 6.6 1.6e-13 50.4 4.6 2.3 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus WD40 PF00400.27 KOS13135.1 - 2.5e-65 214.1 19.2 2.7e-13 49.2 1.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KOS13135.1 - 8.5e-08 31.5 0.0 0.92 9.0 0.0 5.1 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 KOS13135.1 - 0.00075 19.2 0.2 0.46 10.1 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KOS13135.1 - 0.12 10.1 0.4 3.5 5.3 0.1 2.3 2 1 0 3 3 3 0 IKI3 family Bromodomain PF00439.20 KOS13136.1 - 3.2e-59 196.8 0.3 2.6e-21 75.3 0.1 3.8 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 KOS13136.1 - 3.6e-08 32.9 0.0 6.9e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 KOS13136.1 - 0.0021 18.2 9.5 0.36 11.1 0.0 4.4 4 0 0 4 4 4 3 HEAT repeats Vps51 PF08700.6 KOS13137.1 - 9.9e-14 50.9 0.2 2.5e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KOS13137.1 - 9.3e-06 25.5 0.2 2.5e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S41 PF03572.13 KOS13137.1 - 0.032 13.6 0.0 13 5.1 0.0 2.3 1 1 0 2 2 2 0 Peptidase family S41 CoaE PF01121.15 KOS13138.1 - 5e-59 198.7 0.2 6e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KOS13138.1 - 5.2e-06 27.2 0.2 2.7e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS13138.1 - 3.5e-05 24.1 0.1 7.1e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS13138.1 - 5.4e-05 23.0 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS13138.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain CcmH PF03918.9 KOS13138.1 - 0.038 12.9 0.4 0.076 12.0 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF938 PF06080.7 KOS13138.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Viral_helicase1 PF01443.13 KOS13138.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase WD40 PF00400.27 KOS13139.1 - 1.4e-74 243.4 21.5 1e-09 37.8 0.0 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 KOS13139.1 - 1.1e-20 73.5 1.3 2.1e-20 72.6 0.9 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KOS13139.1 - 1.4e-05 23.4 3.3 0.0055 14.9 0.0 4.0 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Utp13 PF08625.6 KOS13139.1 - 0.0033 17.0 0.2 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nbas_N PF15492.1 KOS13139.1 - 0.03 13.4 0.2 8 5.4 0.0 3.5 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 KOS13139.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Hira PF07569.6 KOS13139.1 - 0.13 11.4 0.1 1.1 8.4 0.0 2.7 2 1 0 2 2 2 0 TUP1-like enhancer of split Nucleoporin_N PF08801.6 KOS13139.1 - 0.15 10.7 0.1 15 4.1 0.0 4.0 4 1 0 5 5 5 0 Nup133 N terminal like Proteasome PF00227.21 KOS13140.1 - 1.2e-54 184.4 0.1 1.6e-54 184.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS13140.1 - 1.5e-14 52.9 0.0 2.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Synuclein PF01387.12 KOS13140.1 - 0.019 14.9 1.3 0.044 13.6 0.9 1.5 1 1 0 1 1 1 0 Synuclein I_LWEQ PF01608.12 KOS13140.1 - 0.42 10.5 3.5 0.25 11.3 0.6 1.8 2 0 0 2 2 2 0 I/LWEQ domain DUF4603 PF15376.1 KOS13141.1 - 0.33 8.0 3.6 0.41 7.7 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CcmD PF04995.9 KOS13142.1 - 0.0025 17.4 0.7 0.0025 17.4 0.5 1.9 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) NuA4 PF09340.5 KOS13143.1 - 9.7e-22 76.4 0.1 1.4e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Tropomyosin_1 PF12718.2 KOS13143.1 - 0.011 15.6 0.6 0.017 15.0 0.4 1.2 1 0 0 1 1 1 0 Tropomyosin like Glycos_transf_3 PF00591.16 KOS13144.1 - 5.9e-69 232.2 0.0 9.3e-68 228.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain tRNA-synt_1b PF00579.20 KOS13146.1 - 3.4e-62 210.2 0.0 1.4e-61 208.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) adh_short PF00106.20 KOS13147.1 - 1.8e-17 63.7 0.0 5.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS13147.1 - 7.9e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS13147.1 - 1.6e-07 31.0 0.0 2.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KOS13147.1 - 6.2e-07 29.4 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KOS13147.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KOS13147.1 - 0.0035 17.3 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KOS13147.1 - 0.028 13.2 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4112 PF13430.1 KOS13148.1 - 1.9e-29 101.7 0.1 3e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) TctA PF01970.11 KOS13148.1 - 0.1 10.9 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family AAA_12 PF13087.1 KOS13149.1 - 1.6e-44 151.6 0.0 2.4e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS13149.1 - 6.3e-39 133.9 2.4 6.4e-36 124.1 1.7 2.4 1 1 0 1 1 1 1 AAA domain Dna2 PF08696.6 KOS13149.1 - 3.4e-37 127.7 0.0 1.1e-36 126.1 0.0 1.8 1 1 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.1 KOS13149.1 - 5.6e-15 55.4 0.0 1.7e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS13149.1 - 1.2e-09 37.8 1.5 8.3e-09 35.0 0.5 2.8 2 0 0 2 2 2 1 Part of AAA domain Helicase_RecD PF05127.9 KOS13149.1 - 2e-06 27.5 0.0 5.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KOS13149.1 - 1.4e-05 24.7 0.6 1.2 8.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 KOS13149.1 - 0.00069 19.5 0.0 0.0049 16.8 0.0 2.3 3 0 0 3 3 2 1 Domain of unknown function DUF83 Mg_chelatase PF01078.16 KOS13149.1 - 0.00072 18.7 0.1 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 KOS13149.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MobB PF03205.9 KOS13149.1 - 0.0013 18.4 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KOS13149.1 - 0.0017 17.7 0.1 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KOS13149.1 - 0.0022 17.9 0.4 0.013 15.4 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.12 KOS13149.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 T2SE PF00437.15 KOS13149.1 - 0.0073 15.2 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 KOS13149.1 - 0.0079 15.6 0.0 0.028 13.8 0.0 1.8 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KOS13149.1 - 0.014 14.7 0.0 0.045 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KOS13149.1 - 0.019 14.3 0.3 0.041 13.3 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KOS13149.1 - 0.023 14.8 0.0 0.11 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 KOS13149.1 - 0.044 12.5 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 KOS13149.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 KOS13149.1 - 0.16 10.8 0.0 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KOS13149.1 - 0.19 11.9 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter UvrD-helicase PF00580.16 KOS13149.1 - 0.62 9.3 0.0 0.92 8.7 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain EMP24_GP25L PF01105.19 KOS13150.1 - 2.4e-31 108.8 4.8 4.3e-30 104.7 3.3 2.0 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glycophorin_A PF01102.13 KOS13151.1 - 0.0026 17.5 0.8 0.0048 16.6 0.6 1.5 1 0 0 1 1 1 1 Glycophorin A VSP PF03302.8 KOS13151.1 - 0.015 13.9 0.1 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rifin_STEVOR PF02009.11 KOS13151.1 - 0.037 13.6 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Rifin/stevor family Podoplanin PF05808.6 KOS13151.1 - 0.038 13.5 2.0 0.07 12.6 1.4 1.4 1 0 0 1 1 1 0 Podoplanin DUF4245 PF14030.1 KOS13151.1 - 0.047 13.4 0.4 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Herpes_gE PF02480.11 KOS13151.1 - 0.05 11.8 1.6 0.072 11.3 0.7 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E R3H-assoc PF13902.1 KOS13152.1 - 0.022 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain SH2_2 PF14633.1 KOS13153.1 - 5.9e-69 231.5 0.0 1.3e-68 230.3 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KOS13153.1 - 2.4e-23 82.4 0.1 2.4e-23 82.4 0.1 3.9 3 0 0 3 3 3 1 Death-like domain of SPT6 YqgF PF14639.1 KOS13153.1 - 2.9e-23 82.1 0.0 6.9e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 KOS13153.1 - 6.1e-20 71.2 0.0 1.7e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KOS13153.1 - 1.5e-15 57.0 28.3 1.5e-15 57.0 19.6 3.9 3 1 1 4 4 4 2 Acidic N-terminal SPT6 HTH_44 PF14641.1 KOS13153.1 - 1.9e-06 27.8 0.0 4.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KOS13153.1 - 0.004 16.9 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 KOS13153.1 - 0.0078 16.2 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 S1 RNA binding domain CTD PF12815.2 KOS13153.1 - 0.034 14.5 8.8 0.084 13.2 6.1 1.6 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Oxidored_FMN PF00724.15 KOS13154.1 - 9.6e-61 205.6 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family tRNA_int_endo PF01974.12 KOS13156.1 - 3.5e-16 58.7 0.0 7.4e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain ADH_zinc_N_2 PF13602.1 KOS13157.1 - 1.1e-29 103.8 0.2 3.7e-29 102.1 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KOS13157.1 - 2.7e-17 62.5 0.1 4.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS13157.1 - 1.3e-14 53.8 0.1 4.6e-12 45.6 0.0 3.4 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.10 KOS13157.1 - 0.05 13.2 0.4 0.14 11.7 0.3 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus DUF2493 PF10686.4 KOS13157.1 - 0.084 12.4 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) EF-hand_4 PF12763.2 KOS13158.1 - 1.1e-16 60.4 0.0 2.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 KOS13158.1 - 2.3e-14 52.6 0.1 1.9e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KOS13158.1 - 7.8e-14 50.7 0.0 3.7e-11 42.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain WH2 PF02205.15 KOS13158.1 - 9.9e-10 37.7 1.5 2.4e-09 36.4 1.0 1.7 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.12 KOS13158.1 - 1.3e-07 30.9 0.0 0.00012 21.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_7 PF13499.1 KOS13158.1 - 8.9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF2285 PF10074.4 KOS13158.1 - 0.0017 18.6 0.0 0.0017 18.6 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2285) DUF1227 PF06777.6 KOS13158.1 - 0.067 12.8 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) EF-hand_1 PF00036.27 KOS13158.1 - 0.12 11.7 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF2665 PF11654.3 KOS13159.1 - 2e-14 52.8 0.0 2.3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2416 PF10315.4 KOS13159.1 - 0.025 14.7 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) Fungal_trans PF04082.13 KOS13160.1 - 1.9e-06 26.9 0.1 3.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS13160.1 - 2.3e-05 24.1 10.8 3.9e-05 23.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3038 PF11237.3 KOS13160.1 - 0.05 13.4 0.1 0.05 13.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3038) RRM_1 PF00076.17 KOS13161.1 - 4.9e-57 189.4 0.0 3.1e-18 65.1 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13161.1 - 3.9e-44 148.4 0.0 6.2e-13 48.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13161.1 - 1.6e-12 47.0 0.0 0.00096 18.9 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS13161.1 - 0.00013 21.7 1.3 0.33 10.8 0.0 4.4 4 0 0 4 4 4 1 RNA binding motif DHHW PF14286.1 KOS13161.1 - 0.021 14.1 4.1 0.062 12.6 0.0 2.2 2 0 0 2 2 2 0 DHHW protein Nup35_RRM_2 PF14605.1 KOS13161.1 - 0.2 11.4 0.0 6.3 6.6 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MRP-S25 PF13741.1 KOS13162.1 - 2.3e-48 164.6 0.5 3.4e-48 164.1 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 KOS13162.1 - 0.019 14.8 2.2 0.75 9.6 1.5 2.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF1749 PF08538.5 KOS13163.1 - 1.5e-67 227.6 0.0 2.2e-67 227.0 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KOS13163.1 - 2e-10 40.9 0.1 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS13163.1 - 3.2e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS13163.1 - 0.011 14.9 0.0 1.8 7.7 0.0 2.7 2 1 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KOS13163.1 - 0.058 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme 2-Hacid_dh_C PF02826.14 KOS13164.1 - 1.6e-50 170.7 0.0 2.6e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS13164.1 - 2.3e-34 117.6 0.0 3.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS13164.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KOS13164.1 - 0.0087 15.7 0.1 3.4 7.3 0.1 2.6 2 1 1 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M15_4 PF13539.1 KOS13164.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase zf-C2H2 PF00096.21 KOS13165.1 - 0.049 14.0 0.6 0.12 12.7 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type RRM_1 PF00076.17 KOS13166.1 - 1.2e-10 40.8 0.0 4.8e-05 22.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13166.1 - 1.1e-09 38.1 0.0 1.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13166.1 - 5.3e-05 22.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS13166.1 - 0.48 10.2 2.1 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Limkain b1 FGase PF05013.7 KOS13167.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Dynein_heavy PF03028.10 KOS13169.1 - 3.9e-94 316.0 0.9 7.6e-94 315.1 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 KOS13169.1 - 4.3e-39 133.6 1.3 6.3e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KOS13169.1 - 7.1e-37 126.9 1.7 1.5e-36 125.8 1.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Protein_K PF12283.3 KOS13169.1 - 0.1 12.4 0.6 0.62 9.9 0.3 2.2 2 0 0 2 2 2 0 Bacteriophage protein K Spc7 PF08317.6 KOS13169.1 - 0.11 11.1 29.2 0.31 9.6 0.5 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 KOS13169.1 - 1.4 8.4 45.2 0.15 11.5 1.5 3.3 3 0 0 3 3 3 0 IncA protein DUF948 PF06103.6 KOS13169.1 - 4.7 7.1 11.4 2.1 8.2 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ERM PF00769.14 KOS13169.1 - 6.8 6.1 39.9 1.5 8.2 2.8 3.3 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 KOS13169.1 - 8.6 5.4 11.9 0.23 10.6 0.0 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein EF-hand_1 PF00036.27 KOS13170.1 - 5.2e-25 84.8 4.1 5.3e-07 28.4 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KOS13170.1 - 2.5e-22 78.8 0.4 4.6e-13 49.1 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KOS13170.1 - 1.9e-20 70.8 1.3 6.7e-06 25.5 0.0 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KOS13170.1 - 3e-14 51.6 6.6 0.0016 17.6 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KOS13170.1 - 6.1e-13 48.1 7.6 0.00016 21.1 1.0 4.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KOS13170.1 - 4.2e-07 29.6 3.1 0.13 12.0 0.0 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KOS13170.1 - 3.2e-05 23.7 0.4 0.36 10.7 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.4 KOS13170.1 - 0.00098 19.1 0.4 0.16 12.0 0.1 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DAG_kinase_N PF14513.1 KOS13170.1 - 0.013 15.7 0.9 0.026 14.7 0.4 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus S10_plectin PF03501.10 KOS13170.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 KOS13170.1 - 0.11 12.6 0.0 2.9 7.9 0.0 2.4 2 1 0 2 2 2 0 EF hand DUF1679 PF07914.6 KOS13170.1 - 0.15 10.7 0.3 2 6.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) AA_permease PF00324.16 KOS13171.1 - 0 1616.0 193.8 3e-130 434.7 28.7 4.0 4 0 0 4 4 4 4 Amino acid permease AA_permease_2 PF13520.1 KOS13171.1 - 1.4e-149 498.2 204.5 6.9e-44 150.0 31.2 4.1 4 0 0 4 4 4 4 Amino acid permease DUF2665 PF11654.3 KOS13171.1 - 0.18 11.3 3.3 15 5.2 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2665) Mito_carr PF00153.22 KOS13173.1 - 3.1e-20 71.6 0.0 3e-07 30.0 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein PTH2 PF01981.11 KOS13174.1 - 2.5e-42 143.2 0.2 2.7e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF336 PF03928.9 KOS13174.1 - 0.015 15.0 0.3 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF336) gag-asp_proteas PF13975.1 KOS13174.1 - 0.061 13.1 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease WD40 PF00400.27 KOS13175.1 - 2.6e-21 74.6 16.2 6.6e-06 25.7 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PBP1_TM PF14812.1 KOS13175.1 - 0.19 12.0 8.6 0.54 10.5 6.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 KOS13175.1 - 1.4 9.0 8.7 3.5 7.8 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 KOS13175.1 - 3.7 7.0 9.1 6.5 6.3 6.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Phosducin PF02114.11 KOS13176.1 - 1e-12 47.3 0.0 2.3e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Phosducin DivIC PF04977.10 KOS13176.1 - 0.85 9.1 5.4 2 7.9 3.7 1.5 1 0 0 1 1 1 0 Septum formation initiator GOLD_2 PF13897.1 KOS13176.1 - 2.4 8.3 5.3 0.23 11.6 0.2 1.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking ATP-synt_F PF01990.12 KOS13177.1 - 1.2e-29 102.5 0.1 1.3e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit RmuC PF02646.11 KOS13177.1 - 0.086 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 RmuC family Nol1_Nop2_Fmu PF01189.12 KOS13178.1 - 1e-31 110.4 0.0 4.5e-18 65.6 0.0 3.8 2 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KOS13178.1 - 0.089 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Flavokinase PF01687.12 KOS13178.1 - 0.1 12.5 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Riboflavin kinase FtsJ PF01728.14 KOS13178.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase WW PF00397.21 KOS13179.1 - 0.014 15.2 1.2 0.014 15.2 0.8 2.2 2 0 0 2 2 2 0 WW domain Metallophos PF00149.23 KOS13180.1 - 4.2e-43 147.0 0.1 5.2e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 4HBT_3 PF13622.1 KOS13182.1 - 2.8e-33 115.7 0.0 4.1e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KOS13182.1 - 3.7e-23 81.5 1.6 3.5e-16 59.0 0.0 4.0 2 2 1 3 3 3 3 Acyl-CoA thioesterase Bac_small_YrzI PF09501.5 KOS13182.1 - 0.02 14.7 0.2 0.053 13.4 0.2 1.7 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF1977 PF09320.6 KOS13182.1 - 0.05 13.8 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) GTP_cyclohydroI PF01227.17 KOS13183.1 - 2.1e-74 248.6 0.1 2.5e-74 248.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KOS13183.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 KOS13183.1 - 0.046 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain WD40 PF00400.27 KOS13184.1 - 1.5e-29 100.7 12.9 4.2e-08 32.7 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF3337 PF11816.3 KOS13184.1 - 2.3e-16 60.1 0.0 3.8e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) FdsD PF11390.3 KOS13184.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Nucleopor_Nup85 PF07575.8 KOS13185.1 - 6.7e-69 232.5 0.0 1.8e-68 231.2 0.0 1.7 1 1 0 1 1 1 1 Nup85 Nucleoporin Arch_fla_DE PF04659.8 KOS13185.1 - 0.0022 17.7 0.5 0.26 11.1 0.2 2.9 2 0 0 2 2 2 2 Archaeal flagella protein Abhydrolase_5 PF12695.2 KOS13186.1 - 0.009 15.7 0.0 0.034 13.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS13186.1 - 0.012 14.5 0.0 0.032 13.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme PGAP1 PF07819.8 KOS13186.1 - 0.034 13.7 0.4 0.06 12.9 0.3 1.5 1 1 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 KOS13186.1 - 0.054 12.3 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) CDC73 PF05179.9 KOS13187.1 - 5.4e-50 170.2 0.1 7.4e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Pkinase PF00069.20 KOS13188.1 - 4.1e-44 150.6 0.0 4.5e-42 144.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13188.1 - 5.3e-21 74.8 0.0 1.9e-20 73.0 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS13188.1 - 0.068 11.9 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4448 PF14610.1 KOS13189.1 - 0.22 10.9 0.9 0.45 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) COQ9 PF08511.6 KOS13190.1 - 0.017 14.6 0.1 0.073 12.5 0.0 1.9 2 0 0 2 2 2 0 COQ9 DUF2732 PF10809.3 KOS13190.1 - 0.12 11.9 0.2 0.59 9.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2732) RNA_pol_L_2 PF13656.1 KOS13191.1 - 5.7e-27 92.9 0.1 7e-27 92.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KOS13191.1 - 1.6e-08 33.5 0.0 2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Clp1 PF06807.9 KOS13192.1 - 2.9e-20 72.8 0.0 4.6e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 AAA_28 PF13521.1 KOS13192.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KOS13192.1 - 0.0016 18.1 0.0 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KOS13192.1 - 0.0048 16.9 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KOS13192.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS13192.1 - 0.058 13.3 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KOS13192.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 KOS13192.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 KOS13192.1 - 0.12 11.5 0.0 0.5 9.5 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IMS PF00817.15 KOS13193.1 - 3e-33 114.7 0.0 1.6e-29 102.6 0.0 2.4 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KOS13193.1 - 1.6e-07 31.2 0.0 4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KOS13193.1 - 0.11 12.5 0.1 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif ADH_zinc_N PF00107.21 KOS13194.1 - 1.7e-29 102.0 0.0 2.9e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS13194.1 - 2.1e-13 51.2 0.1 4.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS13194.1 - 7e-11 41.8 0.1 2.7e-09 36.7 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 KOS13195.1 - 2.5e-60 203.8 0.0 3.2e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13195.1 - 3.2e-23 82.1 0.0 4.3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13195.1 - 7.3e-06 25.1 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13195.1 - 0.00025 20.8 0.2 0.0062 16.3 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS13195.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transket_pyr PF02779.19 KOS13196.1 - 4.3e-63 212.0 0.0 6.8e-63 211.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KOS13196.1 - 5.2e-60 202.7 0.0 7.1e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Histone PF00125.19 KOS13197.1 - 2.9e-30 104.1 0.4 4.6e-30 103.5 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KOS13197.1 - 0.00096 19.2 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS13197.1 - 0.016 15.2 0.4 0.065 13.3 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KOS13197.1 - 0.047 12.9 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3305 PF11749.3 KOS13197.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3305) DUF3649 PF12365.3 KOS13198.1 - 5.9 6.5 10.0 2.1e+02 1.5 5.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3649) Peptidase_M50 PF02163.17 KOS13199.1 - 0.00043 19.2 0.0 0.00048 19.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 RabGAP-TBC PF00566.13 KOS13200.1 - 1.5e-53 181.4 0.1 3.3e-53 180.3 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Daxx PF03344.10 KOS13200.1 - 0.0071 14.9 25.0 0.012 14.1 17.3 1.3 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 KOS13200.1 - 0.01 15.1 23.9 0.022 14.0 16.5 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KOS13200.1 - 0.72 7.8 21.5 1.4 6.8 14.9 1.5 1 0 0 1 1 1 0 CDC45-like protein Ebola_NP PF05505.7 KOS13200.1 - 1.3 7.0 17.2 1.9 6.4 11.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein SAPS PF04499.10 KOS13200.1 - 1.8 7.0 11.1 3.8 6.0 7.7 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 KOS13200.1 - 2 6.1 18.4 2.9 5.6 12.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KOS13200.1 - 2.1 6.1 39.7 0.11 10.4 23.3 1.8 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L14 PF00238.14 KOS13201.1 - 7e-34 116.2 0.0 7.9e-34 116.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FtsJ PF01728.14 KOS13202.1 - 2e-50 171.2 0.0 2.6e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KOS13202.1 - 4.6e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS13202.1 - 9.4e-05 22.1 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS13202.1 - 0.0024 17.4 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CbiA PF01656.18 KOS13202.1 - 0.005 16.2 0.1 0.0085 15.5 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain LAP2alpha PF11560.3 KOS13202.1 - 0.036 13.2 0.1 0.056 12.6 0.1 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha NSP13 PF06460.7 KOS13202.1 - 0.15 10.9 0.0 0.81 8.4 0.0 1.8 1 1 0 1 1 1 0 Coronavirus NSP13 PINIT PF14324.1 KOS13203.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 PINIT domain DDE_Tnp_1_2 PF13586.1 KOS13203.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain NAD_kinase PF01513.16 KOS13204.1 - 5.3e-66 222.2 0.0 8.5e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Nucleoporin_FG PF13634.1 KOS13205.1 - 2.2e-35 121.2 130.6 1e-17 64.4 38.4 4.4 1 1 3 4 4 4 3 Nucleoporin FG repeat region Nup54 PF13874.1 KOS13205.1 - 2.9e-24 85.3 5.7 6.2e-24 84.2 3.7 1.7 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 DUF4200 PF13863.1 KOS13205.1 - 0.00042 20.2 3.8 0.0046 16.8 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) HJURP_C PF12347.3 KOS13205.1 - 0.07 12.7 0.1 0.4 10.2 0.1 2.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat RNA_GG_bind PF10258.4 KOS13205.1 - 0.19 11.4 8.4 0.37 10.5 0.8 3.4 2 1 0 3 3 3 0 PHAX RNA-binding domain BMFP PF04380.8 KOS13205.1 - 0.85 9.7 6.9 13 6.0 3.6 2.8 2 0 0 2 2 2 0 Membrane fusogenic activity Caudo_TAP PF02413.12 KOS13205.1 - 1.1 9.4 8.1 0.079 13.1 1.5 2.0 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein UCH PF00443.24 KOS13207.1 - 7.6e-54 182.6 0.0 1.3e-53 181.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS13207.1 - 3.7e-28 98.8 0.0 5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KOS13207.1 - 2.2e-09 37.2 1.8 2.2e-09 37.2 1.3 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein DUF829 PF05705.9 KOS13208.1 - 8.1e-29 101.0 0.4 2.1e-24 86.5 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Rad60-SLD PF11976.3 KOS13209.1 - 3e-12 46.0 0.0 6.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3135 PF11333.3 KOS13209.1 - 0.15 12.1 0.9 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) FHA PF00498.21 KOS13210.1 - 1.7e-08 34.4 0.1 3.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain WD40 PF00400.27 KOS13211.1 - 1.3e-07 31.2 0.0 0.0032 17.3 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat EXS PF03124.9 KOS13212.1 - 1.4e-85 287.3 26.3 1.9e-85 286.9 18.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KOS13212.1 - 2.3e-49 168.6 1.2 3.6e-49 168.0 0.8 1.3 1 0 0 1 1 1 1 SPX domain Dopey_N PF04118.9 KOS13213.1 - 5.2e-103 344.0 0.0 1.3e-102 342.7 0.0 1.7 1 0 0 1 1 1 1 Dopey, N-terminal NOT2_3_5 PF04153.13 KOS13214.1 - 4.9e-38 130.0 1.5 7.8e-38 129.3 1.1 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pkinase PF00069.20 KOS13215.1 - 1.3e-69 234.3 0.0 2.4e-69 233.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13215.1 - 6.7e-37 126.9 0.0 4.5e-33 114.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 KOS13215.1 - 5.1e-16 57.8 0.1 8.7e-16 57.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KOS13215.1 - 1.3e-06 27.6 0.1 2.1e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS13215.1 - 0.0002 20.4 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13215.1 - 0.0091 15.7 0.0 0.03 14.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KOS13215.1 - 0.095 12.0 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.19 KOS13216.1 - 3.4e-150 500.8 0.3 3.9e-150 500.6 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_PrkA PF08298.6 KOS13216.1 - 0.047 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain S-AdoMet_synt_N PF00438.15 KOS13216.1 - 0.069 13.3 0.1 5.1 7.3 0.0 2.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain Chorismate_synt PF01264.16 KOS13217.1 - 4.9e-136 452.7 0.1 7.4e-136 452.1 0.0 1.3 1 0 0 1 1 1 1 Chorismate synthase ArfGap PF01412.13 KOS13217.1 - 1.1e-32 112.3 2.4 1.2e-32 112.1 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Peptidase_S24 PF00717.18 KOS13218.1 - 1.8e-09 37.0 0.1 2.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF4631 PF15450.1 KOS13219.1 - 0.00032 19.1 4.5 0.00047 18.5 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) Lebercilin PF15619.1 KOS13219.1 - 0.00073 19.0 10.4 0.00073 19.0 7.2 1.7 2 0 0 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 KOS13219.1 - 0.0009 18.8 19.2 0.0021 17.7 13.1 1.8 1 1 0 1 1 1 1 IncA protein HAUS-augmin3 PF14932.1 KOS13219.1 - 0.0011 18.2 13.6 0.0024 17.0 9.4 1.6 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 KOS13219.1 - 0.0035 16.0 8.8 0.0065 15.1 6.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.7 KOS13219.1 - 0.0048 17.2 1.8 0.0048 17.2 1.2 3.7 3 1 0 3 3 3 1 SlyX Atg14 PF10186.4 KOS13219.1 - 0.0058 15.6 15.3 0.024 13.6 3.4 2.7 2 1 1 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 Gp58 PF07902.6 KOS13219.1 - 0.0081 14.4 6.7 0.019 13.2 4.6 1.5 1 1 0 1 1 1 1 gp58-like protein DUF4407 PF14362.1 KOS13219.1 - 0.013 14.4 22.1 0.02 13.8 14.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 KOS13219.1 - 0.014 13.8 5.1 0.019 13.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 KOS13219.1 - 0.015 14.4 10.3 0.042 13.0 1.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KOS13219.1 - 0.035 14.3 5.3 2 8.7 0.2 2.8 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KOS13219.1 - 0.036 13.5 17.2 0.22 10.9 11.3 2.2 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 KOS13219.1 - 0.038 13.8 12.8 0.31 10.8 8.9 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.4 KOS13219.1 - 0.051 12.3 5.4 0.068 11.9 3.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.15 KOS13219.1 - 0.059 13.1 11.8 0.28 10.9 8.2 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF3584 PF12128.3 KOS13219.1 - 0.068 10.5 23.2 0.0035 14.7 8.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prominin PF05478.6 KOS13219.1 - 0.074 10.5 5.0 0.092 10.2 3.5 1.1 1 0 0 1 1 1 0 Prominin FH2 PF02181.18 KOS13219.1 - 0.082 11.7 8.8 1.5 7.6 5.0 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain Tropomyosin PF00261.15 KOS13219.1 - 0.087 11.8 18.9 0.43 9.6 5.7 2.8 1 1 1 2 2 2 0 Tropomyosin Mannitol_dh PF01232.18 KOS13219.1 - 0.091 12.6 4.8 0.11 12.4 2.8 1.5 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain DUF812 PF05667.6 KOS13219.1 - 0.11 10.9 21.1 0.49 8.8 14.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) MbeD_MobD PF04899.7 KOS13219.1 - 0.14 12.0 9.8 0.052 13.4 1.4 2.7 1 1 1 2 2 2 0 MbeD/MobD like TBPIP PF07106.8 KOS13219.1 - 0.14 11.6 9.9 0.44 10.0 6.8 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KOS13219.1 - 0.15 11.9 6.9 0.62 9.8 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 KOS13219.1 - 0.16 11.3 5.4 0.37 10.1 3.8 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Cortex-I_coil PF09304.5 KOS13219.1 - 0.2 11.6 12.1 0.49 10.4 6.2 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil COG2 PF06148.6 KOS13219.1 - 0.21 11.4 9.8 2.1 8.2 0.6 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.13 KOS13219.1 - 0.28 10.1 5.6 1.5 7.7 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2383 PF09537.5 KOS13219.1 - 0.3 11.3 11.7 2.8 8.2 2.8 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) V_ATPase_I PF01496.14 KOS13219.1 - 0.3 8.8 8.3 0.16 9.8 1.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 KOS13219.1 - 0.3 10.8 6.7 0.58 9.9 3.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cauli_AT PF03233.8 KOS13219.1 - 0.3 10.7 2.3 3 7.5 1.0 2.5 1 1 2 3 3 3 0 Aphid transmission protein DUF4618 PF15397.1 KOS13219.1 - 0.31 10.3 12.2 0.45 9.8 7.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) End3 PF12761.2 KOS13219.1 - 0.34 10.5 8.4 2.9 7.5 5.8 2.1 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF2229 PF09989.4 KOS13219.1 - 0.43 10.0 2.9 0.81 9.0 2.0 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FliJ PF02050.11 KOS13219.1 - 0.46 10.5 19.9 0.029 14.3 9.7 2.0 2 0 0 2 2 1 0 Flagellar FliJ protein WXG100 PF06013.7 KOS13219.1 - 0.5 10.3 11.8 4.3 7.3 1.2 3.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG YPEB PF14620.1 KOS13219.1 - 0.54 9.2 11.1 0.4 9.6 0.9 2.2 1 1 1 2 2 2 0 YpeB sporulation TMPIT PF07851.8 KOS13219.1 - 0.57 9.1 4.1 0.84 8.6 2.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.1 KOS13219.1 - 0.71 10.3 19.8 20 5.7 3.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) TMF_DNA_bd PF12329.3 KOS13219.1 - 0.73 9.6 18.4 0.84 9.4 3.5 3.0 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 KOS13219.1 - 0.81 9.6 19.2 0.11 12.4 10.5 1.7 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 KOS13219.1 - 1.2 8.9 22.9 4.5 7.1 11.8 2.7 2 1 1 3 3 2 0 Tropomyosin like Phage_GP20 PF06810.6 KOS13219.1 - 1.2 8.5 12.2 3.8 6.9 3.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spectrin PF00435.16 KOS13219.1 - 1.3 9.3 17.5 3.9 7.8 7.0 2.8 1 1 1 2 2 2 0 Spectrin repeat DUF2408 PF10303.4 KOS13219.1 - 1.4 9.0 6.1 3 7.9 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.5 KOS13219.1 - 1.4 9.0 9.2 6.5 6.8 5.2 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KOS13219.1 - 1.5 8.7 6.6 2 8.3 1.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Macoilin PF09726.4 KOS13219.1 - 1.5 7.0 19.3 0.37 9.0 3.9 2.1 1 1 1 2 2 2 0 Transmembrane protein Prefoldin PF02996.12 KOS13219.1 - 1.5 8.4 10.7 3.4 7.3 2.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit HR1 PF02185.11 KOS13219.1 - 1.7 8.4 13.3 0.52 10.0 1.2 2.9 3 0 0 3 3 2 0 Hr1 repeat Vir_act_alpha_C PF10400.4 KOS13219.1 - 2 8.8 12.7 1.4 9.3 2.0 3.7 1 1 2 3 3 3 0 Virulence activator alpha C-term Phage_Mu_Gam PF07352.7 KOS13219.1 - 2.1 7.8 9.4 2.2 7.8 0.6 2.8 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein Spc24 PF08286.6 KOS13219.1 - 2.1 8.0 13.5 2.5 7.8 1.5 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 KOS13219.1 - 2.2 7.2 12.2 3.5 6.5 8.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 KOS13219.1 - 2.4 8.6 10.7 7 7.1 2.0 3.0 1 1 2 3 3 2 0 Syntaxin 6, N-terminal DUF4446 PF14584.1 KOS13219.1 - 2.4 7.9 8.4 1.7 8.4 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) AAA_13 PF13166.1 KOS13219.1 - 2.7 6.3 17.7 0.084 11.3 7.9 1.7 2 1 0 2 2 1 0 AAA domain TMF_TATA_bd PF12325.3 KOS13219.1 - 4.5 7.0 13.5 3 7.5 7.4 2.2 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding Peptidase_S64 PF08192.6 KOS13219.1 - 5.8 5.1 12.3 7.2 4.8 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 ATG16 PF08614.6 KOS13219.1 - 5.9 6.6 23.6 0.32 10.8 5.7 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KOS13219.1 - 6.7 6.6 26.0 0.17 11.8 7.0 3.0 3 1 1 4 4 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 KOS13219.1 - 6.8 6.4 14.0 16 5.2 6.9 2.9 1 1 2 3 3 3 0 Axonemal dynein light chain BTV_NS2 PF04514.7 KOS13219.1 - 7.2 5.3 8.8 5.9 5.6 4.6 1.7 1 1 1 2 2 2 0 Bluetongue virus non-structural protein NS2 Rootletin PF15035.1 KOS13219.1 - 7.5 6.4 16.3 3 7.7 0.8 2.7 2 1 2 4 4 3 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.7 KOS13219.1 - 8.3 6.6 11.1 17 5.6 2.5 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) EAP30 PF04157.11 KOS13219.1 - 9.9 5.2 14.2 7.7 5.6 3.3 2.5 1 1 1 2 2 2 0 EAP30/Vps36 family DUF4140 PF13600.1 KOS13219.1 - 9.9 6.6 21.2 1.2 9.6 4.3 3.1 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) Mis12 PF05859.7 KOS13220.1 - 1.9e-16 60.1 0.2 3.8e-16 59.1 0.0 1.6 2 0 0 2 2 2 1 Mis12 protein DinB_2 PF12867.2 KOS13220.1 - 0.084 13.2 3.7 0.067 13.5 1.4 1.7 2 0 0 2 2 2 0 DinB superfamily NTP_transf_3 PF12804.2 KOS13220.1 - 0.32 11.0 3.0 13 5.8 1.1 2.5 1 1 1 2 2 2 0 MobA-like NTP transferase domain PCI PF01399.22 KOS13222.1 - 6.1e-06 26.4 0.0 2.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 PCI domain WH2 PF02205.15 KOS13223.1 - 2.3e-06 27.0 0.6 8.5e-06 25.2 0.4 2.0 2 0 0 2 2 2 1 WH2 motif Exo70 PF03081.10 KOS13224.1 - 2.1e-32 112.3 0.0 3.2e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Pkinase PF00069.20 KOS13225.1 - 3.9e-27 95.0 0.0 1.1e-26 93.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13225.1 - 1e-13 50.9 0.0 3.2e-13 49.3 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13225.1 - 1e-05 24.6 0.0 2.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13225.1 - 0.00029 20.6 0.1 0.0013 18.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS13225.1 - 0.002 17.1 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS13225.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FA_hydroxylase PF04116.8 KOS13226.1 - 2.3e-15 56.9 9.3 2.3e-15 56.9 6.5 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tyr_Deacylase PF02580.11 KOS13227.1 - 1.1e-42 145.4 0.0 1.4e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec7_N PF12783.2 KOS13228.1 - 7.9e-31 106.7 0.3 2.8e-29 101.6 0.0 3.6 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KOS13228.1 - 0.0011 18.4 0.0 0.0056 16.1 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) ketoacyl-synt PF00109.21 KOS13229.1 - 2.8e-63 213.7 0.0 4.4e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KOS13229.1 - 6.4e-47 160.4 0.1 1.1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KOS13229.1 - 1.1e-32 112.4 0.0 2.3e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KOS13229.1 - 3.3e-27 95.4 0.0 5.2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Septin PF00735.13 KOS13230.1 - 8.1e-108 359.6 0.3 8.1e-108 359.6 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KOS13230.1 - 2.9e-09 36.8 0.0 5.7e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS13230.1 - 2.3e-05 23.9 0.0 0.00044 19.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KOS13230.1 - 2.3e-05 23.6 0.1 7.3e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS13230.1 - 2.5e-05 24.1 4.8 0.0043 16.8 0.1 3.2 2 1 0 3 3 3 2 Dynamin family AIG1 PF04548.11 KOS13230.1 - 0.0018 17.3 0.7 0.0032 16.5 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Strep_SA_rep PF06696.6 KOS13230.1 - 0.0019 17.9 0.8 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Streptococcal surface antigen repeat Ras PF00071.17 KOS13230.1 - 0.0019 17.6 0.4 0.0086 15.4 0.0 2.3 2 1 0 2 2 2 1 Ras family AAA_10 PF12846.2 KOS13230.1 - 0.0035 16.8 0.9 0.0057 16.1 0.6 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KOS13230.1 - 0.0038 17.3 0.7 0.02 15.0 0.0 2.4 1 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KOS13230.1 - 0.0059 16.9 0.2 0.0059 16.9 0.1 2.4 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 KOS13230.1 - 0.018 15.5 0.0 0.063 13.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein T2SE PF00437.15 KOS13230.1 - 0.021 13.7 1.6 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 KOS13230.1 - 0.046 13.0 0.7 0.15 11.3 0.5 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 KOS13230.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KOS13230.1 - 0.069 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KOS13230.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KOS13230.1 - 0.12 11.5 8.1 0.27 10.3 5.6 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit PduV-EutP PF10662.4 KOS13230.1 - 0.16 11.4 0.5 6.4 6.2 0.1 3.0 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KOS13230.1 - 0.31 10.4 0.0 0.31 10.4 0.0 2.6 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KOS13230.1 - 0.35 10.8 5.4 0.46 10.4 0.0 2.9 2 1 0 3 3 3 0 AAA ATPase domain KfrA_N PF11740.3 KOS13230.1 - 1.7 9.1 11.5 4.6 7.7 7.7 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fungal_trans PF04082.13 KOS13231.1 - 9.6e-18 63.9 1.9 2.3e-17 62.7 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KOS13231.1 - 2e-07 30.8 7.1 3.6e-07 29.9 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Translin PF01997.11 KOS13231.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Translin family Glyco_hydro_18 PF00704.23 KOS13232.1 - 2.4e-91 306.7 1.5 2.8e-91 306.5 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TAXi_C PF14541.1 KOS13232.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PTPlike_phytase PF14566.1 KOS13233.1 - 1.5e-119 395.0 0.3 2.6e-41 141.1 0.1 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 KOS13233.1 - 7.3e-08 32.0 0.1 0.18 11.3 0.0 4.2 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS13233.1 - 6.4e-07 28.9 0.1 0.033 13.5 0.0 3.3 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KOS13233.1 - 1.6e-06 28.5 0.0 0.12 12.6 0.0 3.4 3 0 0 3 3 3 2 Tyrosine phosphatase family TFIIE-A_C-term PF11521.3 KOS13233.1 - 0.00042 20.2 0.0 13 5.8 0.0 3.9 4 0 0 4 4 4 2 C-terminal general transcription factor TFIIE alpha LMWPc PF01451.16 KOS13234.1 - 6.9e-34 117.1 0.0 7.8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Maf PF02545.9 KOS13235.1 - 3.7e-51 173.0 0.0 4.6e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Glycos_transf_1 PF00534.15 KOS13236.1 - 5.6e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KOS13236.1 - 9.5e-06 25.8 0.0 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 HXXSHH PF07586.6 KOS13237.1 - 0.039 12.8 1.7 0.064 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Allexi_40kDa PF05549.6 KOS13237.1 - 0.049 12.9 1.7 0.069 12.4 1.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4164 PF13747.1 KOS13237.1 - 0.055 13.6 4.6 0.1 12.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF16 PF01519.11 KOS13237.1 - 0.098 12.8 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 IncA PF04156.9 KOS13237.1 - 0.52 9.8 8.7 1.4 8.4 6.0 1.6 1 1 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 KOS13237.1 - 0.75 9.5 5.6 0.74 9.6 1.6 2.0 1 1 1 2 2 2 0 Prefoldin subunit TBPIP PF07106.8 KOS13237.1 - 0.79 9.2 4.9 1.2 8.7 3.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MFS_1 PF07690.11 KOS13238.1 - 4.4e-21 74.9 35.4 4.6e-15 55.1 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS13238.1 - 2.1e-17 62.8 4.6 2.1e-17 62.8 3.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter AMP-binding PF00501.23 KOS13239.1 - 1.4e-81 274.0 0.2 3.6e-81 272.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS13239.1 - 3e-10 40.9 2.0 1.1e-09 39.1 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RRF PF01765.14 KOS13240.1 - 2.2e-35 121.5 0.7 3.4e-35 120.9 0.5 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Y_phosphatase PF00102.22 KOS13241.1 - 8.7e-36 123.4 0.0 2.4e-35 121.9 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KOS13241.1 - 0.00028 20.4 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TPR_11 PF13414.1 KOS13242.1 - 0.00027 20.5 2.9 0.00027 20.5 2.0 2.7 2 1 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 KOS13242.1 - 0.0029 17.6 0.8 0.014 15.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13242.1 - 0.0046 17.4 1.0 0.0046 17.4 0.7 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13242.1 - 0.017 15.4 1.1 0.017 15.4 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13242.1 - 0.02 14.8 2.3 0.02 14.8 1.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CLTH PF10607.4 KOS13243.1 - 1e-11 44.7 0.0 8.5e-11 41.7 0.0 2.2 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Methyltransf_7 PF03492.10 KOS13243.1 - 0.0032 16.3 1.4 4.3 6.0 0.0 3.1 2 1 0 2 2 2 2 SAM dependent carboxyl methyltransferase UL11 PF11094.3 KOS13243.1 - 0.0085 15.8 0.2 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Membrane-associated tegument protein NIT PF08376.5 KOS13243.1 - 0.032 13.7 7.2 0.021 14.3 2.9 2.1 2 0 0 2 2 2 0 Nitrate and nitrite sensing LisH PF08513.6 KOS13243.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 LisH DOG1 PF14144.1 KOS13243.1 - 8.4 6.5 6.7 3.2 7.8 0.2 3.2 3 0 0 3 3 3 0 Seed dormancy control Glycos_transf_1 PF00534.15 KOS13244.1 - 1e-31 109.7 0.0 1.8e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KOS13244.1 - 2.7e-13 50.0 0.1 2.4e-11 43.7 0.1 2.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KOS13244.1 - 8e-09 35.7 0.0 8.1e-08 32.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS13244.1 - 4.6e-07 30.1 9.5 2.3e-06 27.8 0.1 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KOS13244.1 - 6.9e-07 29.4 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Septin PF00735.13 KOS13245.1 - 1.4e-102 342.5 0.0 2.7e-102 341.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KOS13245.1 - 4.7e-06 26.5 0.0 8.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS13245.1 - 4.7e-05 24.2 0.4 0.00021 22.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS13245.1 - 5.8e-05 22.9 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS13245.1 - 0.00014 21.1 0.1 0.00029 20.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS13245.1 - 0.0002 21.2 3.6 0.037 13.8 0.0 3.1 3 1 1 4 4 4 1 Dynamin family FtsK_SpoIIIE PF01580.13 KOS13245.1 - 0.00028 20.4 0.0 0.00072 19.0 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KOS13245.1 - 0.0005 20.2 0.0 0.0011 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KOS13245.1 - 0.0019 17.7 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 KOS13245.1 - 0.0035 16.8 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KOS13245.1 - 0.0036 16.4 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KOS13245.1 - 0.004 17.6 0.0 0.008 16.6 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 KOS13245.1 - 0.0077 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KOS13245.1 - 0.01 15.6 1.5 0.069 12.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 KOS13245.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KOS13245.1 - 0.016 14.8 0.0 0.083 12.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KOS13245.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.8 KOS13245.1 - 0.018 13.8 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 KOS13245.1 - 0.019 15.3 1.0 0.079 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KOS13245.1 - 0.035 13.5 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KOS13245.1 - 0.035 14.0 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KOS13245.1 - 0.038 13.2 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 KOS13245.1 - 0.04 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 KOS13245.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KOS13245.1 - 0.062 11.9 0.3 0.23 10.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.17 KOS13245.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KOS13245.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS13245.1 - 0.09 12.7 0.5 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AbiH PF14253.1 KOS13245.1 - 0.093 12.3 1.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH SRP54 PF00448.17 KOS13245.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3653 PF12375.3 KOS13245.1 - 0.12 12.5 0.7 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Phage protein AAA_23 PF13476.1 KOS13245.1 - 4 7.7 7.8 11 6.3 0.1 2.5 3 0 0 3 3 2 0 AAA domain SOG2 PF10428.4 KOS13246.1 - 1.1e-60 205.5 6.3 2.8e-60 204.2 4.4 1.6 1 1 0 1 1 1 1 RAM signalling pathway protein DUF892 PF05974.7 KOS13246.1 - 0.11 12.3 0.1 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Corona_S2 PF01601.11 KOS13246.1 - 0.12 10.4 0.1 0.19 9.8 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein E1-E2_ATPase PF00122.15 KOS13247.1 - 3e-57 193.3 0.5 7.3e-57 192.0 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS13247.1 - 2.6e-42 144.4 4.3 2.6e-42 144.4 3.0 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS13247.1 - 3.1e-22 80.0 0.0 4.2e-21 76.3 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS13247.1 - 1.4e-16 60.2 0.0 3.9e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS13247.1 - 3.6e-10 40.3 0.0 1.8e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS13247.1 - 4.3e-08 32.4 0.0 1.4e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS13247.1 - 0.0063 16.1 0.8 0.011 15.3 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MRP-S33 PF08293.6 KOS13248.1 - 3.9e-16 58.8 0.1 4.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 AAA_12 PF13087.1 KOS13249.1 - 4e-58 196.1 0.0 6.4e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS13249.1 - 1.2e-55 188.6 0.0 2.7e-55 187.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 KOS13249.1 - 2e-11 43.8 0.4 0.00019 21.0 0.1 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KOS13249.1 - 3.4e-11 42.7 3.9 7.7e-11 41.5 0.5 2.8 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 KOS13249.1 - 5.4e-10 39.1 1.2 3.2e-06 26.8 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KOS13249.1 - 1.1e-05 25.5 0.7 0.00082 19.5 0.0 3.7 4 1 0 4 4 2 1 AAA domain PhoH PF02562.11 KOS13249.1 - 2e-05 23.9 0.0 0.13 11.4 0.0 2.6 3 0 0 3 3 2 2 PhoH-like protein UvrD-helicase PF00580.16 KOS13249.1 - 4.3e-05 22.9 0.0 0.00011 21.5 0.0 1.6 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 KOS13249.1 - 0.00026 20.9 0.0 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 KOS13249.1 - 0.00039 20.5 0.1 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KOS13249.1 - 0.00084 18.7 0.0 0.0029 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS13249.1 - 0.0015 19.3 0.0 0.0039 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS13249.1 - 0.0015 18.5 0.1 0.0062 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KOS13249.1 - 0.003 17.7 0.0 0.0095 16.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KOS13249.1 - 0.0034 16.3 0.2 0.14 11.1 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KOS13249.1 - 0.0049 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 KOS13249.1 - 0.006 16.4 0.1 0.03 14.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 KOS13249.1 - 0.0075 15.2 0.1 0.022 13.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein UvrD_C PF13361.1 KOS13249.1 - 0.0081 15.6 0.2 0.15 11.5 0.1 2.1 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.22 KOS13249.1 - 0.02 15.2 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Helicase_RecD PF05127.9 KOS13249.1 - 0.023 14.3 0.1 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 Helicase NACHT PF05729.7 KOS13249.1 - 0.025 14.2 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 1 0 NACHT domain Rad17 PF03215.10 KOS13249.1 - 0.057 12.0 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KOS13249.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KOS13249.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KOS13249.1 - 0.094 12.6 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KOS13249.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KOS13249.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS13249.1 - 0.29 11.4 0.0 0.55 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Synaptobrevin PF00957.16 KOS13251.1 - 7.5e-33 111.9 2.0 9.5e-33 111.6 1.4 1.1 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.4 KOS13251.1 - 0.00077 18.8 0.4 0.0018 17.6 0.0 1.9 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 SP_C-Propep PF08999.5 KOS13251.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide RSN1_TM PF13967.1 KOS13251.1 - 0.034 13.7 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Chordopox_A33R PF05966.7 KOS13251.1 - 0.036 12.8 0.3 0.043 12.5 0.2 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein TMEM154 PF15102.1 KOS13251.1 - 0.061 13.0 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family ATP-synt_8 PF00895.15 KOS13251.1 - 0.076 13.2 1.2 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 ATP synthase protein 8 DUF3357 PF11837.3 KOS13251.1 - 0.13 12.0 1.2 0.74 9.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) SoxE PF06525.6 KOS13251.1 - 0.38 9.9 2.8 0.65 9.2 1.9 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) SET PF00856.23 KOS13253.1 - 1.7e-10 41.4 0.1 5e-10 39.9 0.1 1.9 1 1 0 1 1 1 1 SET domain UreD PF01774.12 KOS13254.1 - 1.7e-51 174.6 0.0 2.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Cupin_8 PF13621.1 KOS13255.1 - 1.8e-18 66.9 0.1 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS13255.1 - 8.8e-17 61.3 0.4 8.1e-16 58.2 0.3 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 KOS13255.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) SPC12 PF06645.8 KOS13256.1 - 1.3e-26 92.2 0.2 1.4e-26 92.0 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ni_hydr_CYTB PF01292.15 KOS13256.1 - 0.094 12.0 1.1 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4225 PF13988.1 KOS13256.1 - 0.095 12.1 0.3 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Cytochrom_B558a PF05038.8 KOS13256.1 - 0.1 12.2 0.2 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit PRA1 PF03208.14 KOS13256.1 - 0.12 11.7 0.3 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 PRA1 family protein SdpI PF13630.1 KOS13256.1 - 0.13 11.9 1.3 0.16 11.6 0.9 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family Cytochrom_B_N PF00033.14 KOS13256.1 - 0.34 10.2 2.8 0.43 9.8 1.9 1.2 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1434 PF07254.7 KOS13256.1 - 2 8.2 3.9 1.7 8.4 1.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1434) DUF4349 PF14257.1 KOS13257.1 - 0.00074 18.8 2.0 0.0013 18.0 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Rbsn PF11464.3 KOS13257.1 - 0.034 13.7 3.7 0.27 10.8 0.7 2.9 2 1 0 2 2 2 0 Rabenosyn Rab binding domain EutA PF06277.6 KOS13257.1 - 0.071 11.7 0.5 0.08 11.5 0.3 1.3 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutA DnaJ-X PF14308.1 KOS13259.1 - 1.2e-38 132.4 8.4 1.2e-38 132.4 5.8 2.8 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KOS13259.1 - 1.7e-26 91.6 0.6 1.7e-26 91.6 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain VIT1 PF01988.14 KOS13259.1 - 0.0071 15.8 0.7 0.015 14.8 0.5 1.4 1 0 0 1 1 1 1 VIT family IBR PF01485.16 KOS13259.1 - 0.092 12.6 0.3 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 IBR domain Atrophin-1 PF03154.10 KOS13259.1 - 0.43 8.6 7.4 0.066 11.3 2.5 1.6 2 0 0 2 2 2 0 Atrophin-1 family RRN3 PF05327.6 KOS13259.1 - 0.51 8.3 6.6 0.81 7.7 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TSGP1 PF07771.6 KOS13259.1 - 5.1 7.0 9.5 12 5.8 6.6 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 Inositol_P PF00459.20 KOS13260.1 - 5.6e-60 202.9 0.0 6.6e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family UBX PF00789.15 KOS13261.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 UBX domain CAF-1_p150 PF11600.3 KOS13261.1 - 1.4e-05 24.6 32.7 2.1e-05 24.0 22.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA PF00627.26 KOS13261.1 - 0.0092 15.7 0.0 0.036 13.9 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 KOS13261.1 - 0.039 14.0 1.7 0.062 13.4 0.6 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Cytochrome_C554 PF13435.1 KOS13261.1 - 7.4 6.6 9.8 1.7 8.7 3.3 2.5 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Asp PF00026.18 KOS13262.1 - 3.1e-64 217.2 8.9 3.8e-64 216.9 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KOS13262.1 - 2.2e-07 30.9 0.5 5.3e-07 29.7 0.4 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KOS13262.1 - 9e-07 29.3 5.1 0.0023 18.4 0.1 3.2 3 1 0 3 3 3 2 Aspartyl protease RVP PF00077.15 KOS13262.1 - 0.038 13.9 0.2 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KOS13262.1 - 0.058 13.2 0.1 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Mgm101p PF06420.7 KOS13263.1 - 9.2e-79 262.6 0.0 1.2e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CBFB_NFYA PF02045.10 KOS13264.1 - 3.5e-29 101.1 2.5 3.5e-29 101.1 1.7 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MRP-L47 PF06984.8 KOS13265.1 - 2.1e-18 65.9 1.5 3.6e-18 65.2 1.1 1.5 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 KOS13265.1 - 0.0061 16.2 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3703 PF12487.3 KOS13265.1 - 0.17 11.5 4.1 0.72 9.5 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3703) DUF1162 PF06650.7 KOS13266.1 - 2.5e-54 184.3 0.0 6.6e-52 176.4 0.0 3.7 3 2 1 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KOS13266.1 - 3.3e-39 133.0 0.2 8.9e-39 131.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KOS13266.1 - 0.00027 21.0 0.0 0.00092 19.3 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Ribosomal_L34e PF01199.13 KOS13267.1 - 6.1e-36 122.5 4.7 7.7e-36 122.2 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 KOS13267.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c7 FhuF_C PF11575.3 KOS13267.1 - 0.03 13.9 3.3 2 8.1 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Phage_int_SAM_2 PF12834.2 KOS13267.1 - 0.078 13.3 0.5 4.7 7.6 0.0 2.4 2 1 0 2 2 2 0 Phage integrase, N-terminal DUF1428 PF07237.6 KOS13267.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Fcf1 PF04900.7 KOS13268.1 - 9.9e-40 134.7 0.9 9.9e-40 134.7 0.7 1.5 2 0 0 2 2 2 1 Fcf1 Hist_deacetyl PF00850.14 KOS13269.1 - 3.2e-82 276.2 0.0 4.4e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain WD40 PF00400.27 KOS13270.1 - 1.5e-61 202.2 17.5 2.7e-09 36.5 0.0 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KOS13270.1 - 8.2e-12 44.6 0.2 1.9e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS13270.1 - 1.8e-09 37.0 0.2 5.1e-09 35.5 0.2 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KOS13270.1 - 3.7e-08 31.9 13.2 0.15 10.1 0.0 6.1 4 1 2 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS13270.1 - 4.1e-05 22.4 0.0 0.13 10.9 0.0 3.3 1 1 2 3 3 3 2 Nup133 N terminal like X PF00739.14 KOS13270.1 - 0.024 14.5 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Trans-activation protein X BAF1_ABF1 PF04684.8 KOS13270.1 - 0.083 11.7 0.5 0.14 10.9 0.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DHC_N1 PF08385.7 KOS13271.1 - 7.2e-125 417.5 0.0 1.5e-124 416.5 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KOS13271.1 - 3.9e-107 358.2 0.0 3.8e-106 355.0 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KOS13271.1 - 4.7e-70 235.7 0.0 1.9e-69 233.7 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 KOS13271.1 - 1.9e-29 102.1 0.0 2.3e-12 46.8 0.0 6.2 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KOS13271.1 - 2.7e-22 79.1 0.0 1.6e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_8 PF12780.2 KOS13271.1 - 1.5e-20 73.2 0.0 3.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_22 PF13401.1 KOS13271.1 - 1.9e-16 60.3 3.3 0.00018 21.6 0.0 6.6 7 1 0 7 7 6 4 AAA domain AAA PF00004.24 KOS13271.1 - 8.6e-13 48.6 0.0 0.015 15.4 0.0 5.5 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KOS13271.1 - 1.3e-10 40.8 0.6 0.12 12.1 0.0 5.1 4 0 0 4 4 4 2 Part of AAA domain AAA_16 PF13191.1 KOS13271.1 - 3e-07 30.5 29.6 0.062 13.2 0.0 8.2 7 2 1 8 8 7 4 AAA ATPase domain AAA_17 PF13207.1 KOS13271.1 - 7.5e-07 29.9 0.0 0.85 10.4 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KOS13271.1 - 1.4e-06 28.2 10.0 0.45 10.3 0.0 6.3 6 0 0 6 6 6 2 AAA domain Sigma54_activ_2 PF14532.1 KOS13271.1 - 1.5e-06 28.3 0.1 2 8.4 0.0 5.6 5 0 0 5 5 5 1 Sigma-54 interaction domain AAA_14 PF13173.1 KOS13271.1 - 3e-06 27.1 0.0 0.77 9.6 0.0 4.8 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KOS13271.1 - 2.1e-05 23.7 0.0 0.033 13.2 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 KOS13271.1 - 4.2e-05 23.8 0.0 4.3 7.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 KOS13271.1 - 0.00052 19.7 4.2 0.72 9.4 0.0 5.0 4 1 0 4 4 4 1 NACHT domain RNA_helicase PF00910.17 KOS13271.1 - 0.0044 17.1 0.0 13 6.0 0.0 3.8 3 0 0 3 3 3 0 RNA helicase UPF0079 PF02367.12 KOS13271.1 - 0.0046 16.5 0.5 4.1 7.0 0.0 4.0 4 0 0 4 4 4 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KOS13271.1 - 0.0068 16.0 0.5 2.4 7.6 0.0 4.3 6 0 0 6 6 5 1 AAA domain Mg_chelatase PF01078.16 KOS13271.1 - 0.011 14.8 0.9 3.5 6.7 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KOS13271.1 - 0.015 15.5 0.1 25 5.1 0.0 4.6 5 0 0 5 5 5 0 ABC transporter NPV_P10 PF05531.7 KOS13271.1 - 0.021 15.0 1.1 0.46 10.7 0.3 3.9 3 0 0 3 3 1 0 Nucleopolyhedrovirus P10 protein PhoH PF02562.11 KOS13271.1 - 0.024 13.8 0.5 27 3.9 0.0 4.2 4 0 0 4 4 4 0 PhoH-like protein Reo_sigmaC PF04582.7 KOS13271.1 - 0.028 13.6 1.6 0.33 10.0 0.1 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein cobW PF02492.14 KOS13271.1 - 0.064 12.6 0.3 0.93 8.9 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 KOS13271.1 - 0.065 12.6 0.0 1.2 8.5 0.0 2.8 3 0 0 3 3 2 0 Guanylate kinase Arch_ATPase PF01637.13 KOS13271.1 - 0.12 12.0 0.0 1.2 8.7 0.0 2.7 4 0 0 4 4 3 0 Archaeal ATPase AAA_24 PF13479.1 KOS13271.1 - 0.39 10.2 0.1 84 2.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 KOS13272.1 - 2.1e-45 154.1 0.1 7e-45 152.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS13272.1 - 3.8e-09 36.4 0.3 1.2e-08 34.8 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KOS13272.1 - 1e-07 32.0 0.1 2.4e-07 30.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS13272.1 - 1.3e-06 28.4 0.0 4e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS13272.1 - 1.4e-06 28.4 0.2 0.00052 20.1 0.2 3.1 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KOS13272.1 - 8.9e-06 24.8 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 KOS13272.1 - 0.00021 20.4 0.1 0.00072 18.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KOS13272.1 - 0.00026 21.0 0.1 0.00076 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KOS13272.1 - 0.00039 20.3 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS13272.1 - 0.00045 19.9 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KOS13272.1 - 0.00062 19.4 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KOS13272.1 - 0.00074 19.6 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KOS13272.1 - 0.00091 18.9 0.2 0.032 13.8 0.0 2.7 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 KOS13272.1 - 0.0017 18.6 0.0 0.013 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS13272.1 - 0.0018 19.0 0.0 0.0051 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 KOS13272.1 - 0.0024 17.6 0.2 0.0093 15.6 0.1 2.1 1 1 0 1 1 1 1 NTPase AAA_33 PF13671.1 KOS13272.1 - 0.0028 17.5 0.0 0.0075 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS13272.1 - 0.0036 16.7 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.1 KOS13272.1 - 0.0046 16.5 0.1 0.028 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KOS13272.1 - 0.0048 16.0 0.1 0.014 14.6 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KOS13272.1 - 0.0053 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS13272.1 - 0.0057 16.0 0.7 0.048 13.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KOS13272.1 - 0.0062 16.2 0.1 0.058 13.0 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase UPF0079 PF02367.12 KOS13272.1 - 0.007 15.9 0.0 0.025 14.1 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KOS13272.1 - 0.0071 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KOS13272.1 - 0.0084 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_23 PF13476.1 KOS13272.1 - 0.009 16.3 0.7 0.51 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KOS13272.1 - 0.011 15.3 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KOS13272.1 - 0.026 14.1 0.1 0.063 12.9 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein Vinculin PF01044.14 KOS13272.1 - 0.029 12.3 0.1 0.04 11.9 0.0 1.1 1 0 0 1 1 1 0 Vinculin family Parvo_NS1 PF01057.12 KOS13272.1 - 0.056 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 KOS13272.1 - 0.061 12.4 0.3 0.5 9.4 0.0 2.4 3 0 0 3 3 3 0 KaiC AFG1_ATPase PF03969.11 KOS13272.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.21 KOS13272.1 - 0.09 12.2 0.1 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KOS13272.1 - 0.1 11.5 0.2 0.46 9.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KOS13272.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RIG-I_C-RD PF11648.3 KOS13272.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of RIG-I AAA_10 PF12846.2 KOS13272.1 - 0.14 11.6 1.4 1.3 8.3 0.1 2.8 2 1 1 3 3 3 0 AAA-like domain CTDII PF01556.13 KOS13273.1 - 2.3e-27 94.7 0.1 5.2e-21 74.3 0.0 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 KOS13273.1 - 3.1e-23 81.2 1.1 5e-23 80.6 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KOS13273.1 - 8.5e-12 44.9 17.8 1.2e-11 44.4 11.6 1.8 2 0 0 2 2 2 1 DnaJ central domain Transketolase_N PF00456.16 KOS13274.1 - 4.3e-144 479.4 0.1 5.5e-144 479.0 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KOS13274.1 - 1e-39 135.8 0.0 2.2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KOS13274.1 - 1.7e-14 53.8 0.0 4.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KOS13274.1 - 4.7e-05 22.2 0.1 7.7e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KOS13274.1 - 0.00063 18.7 0.1 0.0028 16.6 0.1 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KOS13274.1 - 0.0061 16.1 1.2 0.12 11.9 0.8 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Rhabdo_M1 PF03342.8 KOS13274.1 - 0.073 12.2 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) CBF PF03914.12 KOS13276.1 - 2.6e-40 137.5 0.8 3.2e-39 134.0 0.0 2.7 3 0 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.15 KOS13276.1 - 0.012 13.9 0.2 0.51 8.5 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Acyl_transf_1 PF00698.16 KOS13277.1 - 3.9e-13 49.4 3.5 1.7e-10 40.7 0.3 2.3 2 0 0 2 2 2 2 Acyl transferase domain Daxx PF03344.10 KOS13278.1 - 4.7e-07 28.7 11.6 4.7e-07 28.7 8.1 2.3 2 1 0 2 2 2 1 Daxx Family Nop14 PF04147.7 KOS13278.1 - 4.8e-05 21.5 20.7 7.9e-05 20.8 14.3 1.2 1 0 0 1 1 1 1 Nop14-like family DUF1510 PF07423.6 KOS13278.1 - 0.0013 18.1 15.4 0.0027 17.1 10.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KOS13278.1 - 0.15 9.7 1.2 0.2 9.3 0.8 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KOS13278.1 - 2.1 7.7 11.1 0.13 11.7 3.6 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Herpes_LMP1 PF05297.6 KOS13278.1 - 2.1 7.1 16.2 3.2 6.5 11.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LsmAD PF06741.8 KOS13279.1 - 1.8e-23 82.4 4.8 3.9e-23 81.3 3.3 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KOS13279.1 - 3.3e-07 30.1 0.1 7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.20 KOS13280.1 - 1.1e-57 195.2 0.0 1.8e-56 191.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13280.1 - 7.4e-26 90.7 0.0 2.2e-25 89.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 KOS13280.1 - 1.7e-12 47.1 0.0 6e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.1 KOS13280.1 - 1.5e-06 27.3 0.0 3.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS13280.1 - 4.6e-05 22.5 0.0 7.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS13280.1 - 0.0014 18.3 3.0 0.011 15.4 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Metallophos PF00149.23 KOS13281.1 - 2.7e-10 40.0 0.0 5.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS13281.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 KOS13282.1 - 7.1e-45 149.3 20.1 1.9e-09 37.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KOS13282.1 - 2.4e-05 24.0 5.8 0.014 15.1 0.0 4.3 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term TFIIS_M PF07500.9 KOS13283.1 - 8.6e-29 99.9 4.9 8e-28 96.8 0.7 2.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KOS13283.1 - 3.7e-19 68.0 7.6 5.9e-19 67.4 5.3 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KOS13283.1 - 4.7e-09 35.6 0.6 4.6e-08 32.4 0.4 2.5 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Borrelia_REV PF03978.8 KOS13283.1 - 0.011 15.5 1.4 0.011 15.5 1.0 2.3 2 1 0 2 2 2 0 Borrelia burgdorferi REV protein Baculo_LEF5_C PF11792.3 KOS13283.1 - 0.15 11.4 0.6 0.35 10.2 0.2 1.8 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain ARGLU PF15346.1 KOS13283.1 - 3.9 7.2 9.3 0.32 10.7 1.0 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Exo_endo_phos PF03372.18 KOS13284.1 - 6.9e-17 62.2 0.4 8.8e-17 61.8 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3123 PF11321.3 KOS13284.1 - 2.6 8.3 6.6 6.8 7.0 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) polyprenyl_synt PF00348.12 KOS13285.1 - 1.6e-41 141.8 0.1 2.7e-36 124.7 0.0 3.7 2 1 0 2 2 2 2 Polyprenyl synthetase SDH_alpha PF03313.10 KOS13286.1 - 6.6e-89 297.6 1.7 1e-88 297.0 1.2 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KOS13286.1 - 2.5e-53 180.3 0.0 5.3e-53 179.2 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain SKIP_SNW PF02731.10 KOS13287.1 - 2.3e-65 218.8 2.9 2.3e-65 218.8 2.0 2.8 4 0 0 4 4 4 1 SKIP/SNW domain ATPgrasp_YheCD PF14398.1 KOS13287.1 - 0.028 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp ThiF PF00899.16 KOS13288.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family Coprogen_oxidas PF01218.13 KOS13289.1 - 1.7e-101 338.7 0.1 2.1e-65 220.2 0.0 2.5 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase zf-C3HC4_3 PF13920.1 KOS13290.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Porphobil_deam PF01379.15 KOS13292.1 - 7.9e-69 230.8 0.0 9.6e-66 220.7 0.0 2.1 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KOS13292.1 - 3e-16 59.2 0.1 8.1e-16 57.9 0.1 1.8 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain C2 PF00168.25 KOS13293.1 - 6.2e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Peptidase_M41 PF01434.13 KOS13294.1 - 4.9e-72 241.8 0.2 2.1e-71 239.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KOS13294.1 - 1.1e-42 145.3 0.0 2.5e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KOS13294.1 - 6.4e-10 39.1 0.1 3e-09 37.0 0.1 2.2 1 1 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 KOS13294.1 - 0.00053 20.1 0.1 0.3 11.2 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KOS13294.1 - 0.0011 19.7 0.0 0.0052 17.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KOS13294.1 - 0.002 17.8 0.5 0.0064 16.2 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KOS13294.1 - 0.0067 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 KOS13294.1 - 0.0098 15.8 0.3 0.17 11.8 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KOS13294.1 - 0.024 14.3 0.1 0.11 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KOS13294.1 - 0.025 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KOS13294.1 - 0.025 13.6 0.0 0.076 12.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KOS13294.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KOS13294.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Aminotran_1_2 PF00155.16 KOS13295.1 - 2.4e-34 118.8 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Proteasome PF00227.21 KOS13296.1 - 3.4e-28 98.2 0.0 4e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit CUE PF02845.11 KOS13297.1 - 1.9e-10 40.0 0.0 3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain HMG-CoA_red PF00368.13 KOS13300.1 - 5.3e-159 528.8 3.8 7.8e-159 528.2 2.6 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KOS13300.1 - 3.2e-16 59.1 0.9 1.8e-08 33.9 0.3 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KOS13300.1 - 0.001 17.0 0.1 0.0016 16.4 0.0 1.2 1 0 0 1 1 1 1 Patched family Aminotran_1_2 PF00155.16 KOS13301.1 - 3.6e-46 157.7 0.0 4.1e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KOS13301.1 - 0.0001 21.1 0.0 0.0011 17.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KOS13301.1 - 0.00062 18.1 0.0 0.001 17.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KOS13301.1 - 0.0082 15.2 1.5 0.016 14.2 0.2 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DJ-1_PfpI PF01965.19 KOS13302.1 - 6.8e-26 90.4 0.1 8.9e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KOS13302.1 - 2.1e-11 43.4 0.0 2.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KOS13302.1 - 0.097 12.2 0.3 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KOS13302.1 - 0.15 11.5 0.2 0.26 10.7 0.1 1.3 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Cyt-b5 PF00173.23 KOS13303.1 - 5.1e-24 83.8 0.0 1.2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KOS13303.1 - 5.8e-10 39.5 26.5 8.6e-10 39.0 14.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 KOS13303.1 - 0.052 13.2 8.4 0.42 10.2 1.2 2.5 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Methyltransf_23 PF13489.1 KOS13304.1 - 6.5e-24 84.4 0.0 1.6e-23 83.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS13304.1 - 1.8e-19 70.0 0.0 5e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS13304.1 - 2.1e-14 53.3 0.0 1.3e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS13304.1 - 3.2e-14 53.4 0.2 1.4e-13 51.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS13304.1 - 9.6e-14 51.6 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS13304.1 - 3e-11 43.5 0.1 8.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS13304.1 - 5.1e-08 32.9 2.8 8.2e-08 32.2 1.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KOS13304.1 - 1.4e-07 30.8 0.0 4.3e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KOS13304.1 - 1.1e-06 27.9 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KOS13304.1 - 5.2e-06 25.7 0.0 7.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 KOS13304.1 - 0.00039 19.2 0.0 0.00072 18.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KOS13304.1 - 0.00091 18.6 0.1 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KOS13304.1 - 0.027 13.6 0.1 0.087 11.9 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.1 KOS13304.1 - 0.052 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KOS13304.1 - 0.083 12.2 0.2 0.75 9.1 0.1 2.0 1 1 0 1 1 1 0 Nodulation protein S (NodS) ADH_zinc_N PF00107.21 KOS13304.1 - 0.79 9.2 3.5 0.26 10.8 0.2 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DnaJ PF00226.26 KOS13305.1 - 1.5e-15 56.6 3.8 1.5e-15 56.6 2.6 2.2 2 0 0 2 2 2 1 DnaJ domain CAP_N PF01213.14 KOS13305.1 - 0.95 8.6 6.3 1.4 8.1 4.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DinB_2 PF12867.2 KOS13306.1 - 0.00016 22.0 0.9 0.99 9.7 0.0 3.1 1 1 2 3 3 3 1 DinB superfamily Cauli_DNA-bind PF03310.8 KOS13306.1 - 0.0046 16.7 4.1 4.3 7.2 0.0 3.7 1 1 3 4 4 4 2 Caulimovirus DNA-binding protein DXP_redisom_C PF08436.7 KOS13306.1 - 0.015 15.2 1.4 23 4.9 0.0 3.3 1 1 2 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal DUF1569 PF07606.6 KOS13306.1 - 0.021 14.7 1.9 23 4.8 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1569) DUF3628 PF12300.3 KOS13306.1 - 0.021 14.8 0.0 0.67 9.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3628) YccV-like PF08755.6 KOS13306.1 - 0.047 13.6 0.0 71 3.4 0.0 3.2 3 0 0 3 3 3 0 Hemimethylated DNA-binding protein YccV like YqzE PF14038.1 KOS13306.1 - 0.063 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 YqzE-like protein DUF1414 PF07208.6 KOS13306.1 - 0.11 12.1 0.0 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) RasGAP_C PF03836.10 KOS13307.1 - 6.4e-34 116.6 0.2 6.4e-34 116.6 0.2 2.5 2 1 1 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 KOS13307.1 - 2.6e-24 85.9 0.0 2.6e-24 85.9 0.0 2.6 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KOS13307.1 - 1e-14 52.6 41.9 0.017 14.6 0.2 10.5 10 0 0 10 10 10 7 IQ calmodulin-binding motif CH PF00307.26 KOS13307.1 - 3.7e-11 43.0 0.0 1.1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF3818 PF12825.2 KOS13308.1 - 5.8e-76 255.3 0.3 8.8e-76 254.7 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KOS13308.1 - 8.9e-05 22.1 0.0 0.00033 20.2 0.0 1.9 1 1 0 1 1 1 1 PX-associated SelR PF01641.13 KOS13308.1 - 0.78 9.4 3.2 15 5.2 0.2 3.1 1 1 1 3 3 3 0 SelR domain Spc97_Spc98 PF04130.8 KOS13309.1 - 3.4e-110 368.9 0.0 4.2e-110 368.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family FAT PF02259.18 KOS13309.1 - 0.013 14.5 0.5 0.021 13.8 0.3 1.4 1 0 0 1 1 1 0 FAT domain SART-1 PF03343.8 KOS13310.1 - 1e-102 344.5 31.6 1.2e-102 344.2 21.9 1.1 1 0 0 1 1 1 1 SART-1 family tRNA-synt_2 PF00152.15 KOS13311.1 - 1.1e-98 330.1 0.0 1.4e-98 329.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KOS13311.1 - 0.0019 17.7 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Ndc1_Nup PF09531.5 KOS13312.1 - 2.8e-40 138.3 3.2 4.3e-40 137.7 2.2 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup LIM PF00412.17 KOS13314.1 - 4.5e-27 93.8 30.9 3.5e-13 49.3 5.8 4.1 3 1 0 3 3 3 3 LIM domain MFS_1 PF07690.11 KOS13315.1 - 2.1e-26 92.5 26.7 2.1e-26 92.5 18.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sedlin_N PF04628.8 KOS13316.1 - 9.5e-20 70.8 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KOS13316.1 - 0.029 14.0 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 Sybindin-like family G-patch PF01585.18 KOS13317.1 - 1.8e-10 40.4 0.1 3.8e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 KOS13317.1 - 0.00072 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13317.1 - 0.005 16.7 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2015 PF09435.5 KOS13318.1 - 1.3e-25 89.6 0.0 2.2e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Oxidored_q1 PF00361.15 KOS13318.1 - 0.065 12.4 0.1 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains CDI PF02234.14 KOS13318.1 - 0.091 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor PDZ_2 PF13180.1 KOS13319.1 - 0.0045 16.8 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KOS13319.1 - 0.046 13.8 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) NfeD PF01957.13 KOS13319.1 - 0.26 11.4 9.3 0.11 12.6 0.5 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding SEP PF08059.8 KOS13320.1 - 1.7e-26 92.3 0.3 7.2e-26 90.3 0.0 2.2 3 0 0 3 3 3 1 SEP domain UBX PF00789.15 KOS13320.1 - 3.2e-16 59.1 0.0 5.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KOS13320.1 - 1.3e-15 56.6 0.4 2.2e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain efb-c PF12199.3 KOS13320.1 - 0.094 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Ribosomal_L4 PF00573.17 KOS13321.1 - 8.9e-57 191.5 0.0 1.2e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CAP59_mtransfer PF11735.3 KOS13323.1 - 3e-48 164.1 1.3 2.7e-47 161.0 0.0 2.3 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 COG2 PF06148.6 KOS13323.1 - 2.9e-16 59.5 0.4 1.1e-15 57.6 0.2 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 KOS13323.1 - 5.8e-10 39.3 0.3 2.6e-09 37.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 KOS13323.1 - 0.0021 17.8 2.2 0.017 14.9 1.0 2.8 1 1 1 2 2 2 1 Vps51/Vps67 DUF2450 PF10475.4 KOS13323.1 - 0.053 12.4 2.9 0.096 11.5 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) EMP24_GP25L PF01105.19 KOS13323.1 - 0.063 12.9 0.8 0.12 12.0 0.5 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Zw10 PF06248.8 KOS13323.1 - 0.3 9.2 3.8 0.49 8.4 2.6 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.7 KOS13323.1 - 0.32 10.8 2.2 0.99 9.2 0.2 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.22 KOS13324.1 - 7.9e-44 149.2 0.0 2.6e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS13324.1 - 1.1e-38 133.2 37.6 1.9e-24 86.5 9.9 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS13324.1 - 2.2e-12 46.7 0.2 0.0025 17.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS13324.1 - 6.5e-10 38.3 0.6 3.8e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS13324.1 - 9.3e-08 32.6 0.0 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KOS13324.1 - 1e-07 32.2 0.0 0.17 11.7 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KOS13324.1 - 4e-07 30.2 0.8 0.00025 21.0 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KOS13324.1 - 2.5e-06 27.0 0.1 0.039 13.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 KOS13324.1 - 3e-06 27.3 0.2 0.13 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KOS13324.1 - 9.4e-05 21.9 0.0 0.07 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain T2SE PF00437.15 KOS13324.1 - 0.00015 20.7 0.1 0.0076 15.1 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KOS13324.1 - 0.00018 21.0 0.1 0.19 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.12 KOS13324.1 - 0.00022 20.8 0.4 0.073 12.5 0.0 3.3 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein DUF87 PF01935.12 KOS13324.1 - 0.00027 20.8 2.3 0.0051 16.6 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KOS13324.1 - 0.00044 20.7 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KOS13324.1 - 0.00054 20.7 0.0 0.022 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS13324.1 - 0.0006 19.0 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KOS13324.1 - 0.001 19.0 0.0 0.3 11.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KOS13324.1 - 0.0021 17.9 0.0 0.35 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 KOS13324.1 - 0.0031 17.1 2.3 0.51 9.9 0.3 3.2 2 1 0 2 2 2 1 NACHT domain MobB PF03205.9 KOS13324.1 - 0.0041 16.8 0.3 0.062 13.0 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KOS13324.1 - 0.0047 17.2 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KOS13324.1 - 0.0064 16.2 0.6 0.45 10.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) cobW PF02492.14 KOS13324.1 - 0.0081 15.6 2.3 1.5 8.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KOS13324.1 - 0.017 14.5 0.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 KOS13324.1 - 0.024 14.3 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 NTPase TrwB_AAD_bind PF10412.4 KOS13324.1 - 0.03 12.9 0.5 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 KOS13324.1 - 0.037 14.1 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KOS13324.1 - 0.049 13.8 0.0 3.1 7.9 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KOS13324.1 - 0.052 12.6 0.2 0.69 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KOS13324.1 - 0.077 12.7 0.8 0.74 9.6 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain Zeta_toxin PF06414.7 KOS13324.1 - 0.089 11.8 0.2 0.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 KOS13324.1 - 0.21 11.4 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.6 KOS13324.1 - 0.27 9.8 0.0 0.62 8.6 0.0 1.5 1 0 0 1 1 1 0 PrkA AAA domain Abhydrolase_5 PF12695.2 KOS13325.1 - 0.00015 21.5 0.1 0.0005 19.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS13325.1 - 0.00055 19.8 0.1 0.0012 18.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.5 KOS13325.1 - 0.0011 17.9 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.8 KOS13325.1 - 0.0027 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein CN_hydrolase PF00795.17 KOS13327.1 - 2.2e-13 49.9 0.0 5.3e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DGCR6 PF07324.6 KOS13328.1 - 0.00025 20.6 0.3 0.0009 18.7 0.0 1.8 2 0 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein Peptidase_S9 PF00326.16 KOS13329.1 - 5.3e-52 176.1 1.0 7.9e-52 175.5 0.2 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS13329.1 - 1.5e-11 44.2 0.5 3.6e-11 43.0 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS13329.1 - 0.0069 15.9 0.0 0.058 12.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KOS13329.1 - 0.011 14.5 0.1 0.043 12.5 0.1 1.8 1 1 0 1 1 1 0 Carboxylesterase family PsbN PF02468.10 KOS13330.1 - 0.026 14.1 2.1 0.062 12.9 1.5 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Sporozoite_P67 PF05642.6 KOS13332.1 - 2.1 6.1 15.0 0.16 9.8 6.5 1.7 1 1 1 2 2 2 0 Sporozoite P67 surface antigen SKG6 PF08693.5 KOS13333.1 - 7.9e-05 21.8 2.1 0.0001 21.5 1.4 1.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Lamp PF01299.12 KOS13333.1 - 0.048 12.8 0.7 0.048 12.8 0.5 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Shisa PF13908.1 KOS13333.1 - 0.059 13.5 9.1 0.11 12.6 6.3 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF788 PF05620.6 KOS13334.1 - 3.6e-25 88.7 0.1 4.3e-25 88.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Pox_P35 PF03213.9 KOS13336.1 - 0.3 10.0 1.2 0.43 9.5 0.1 1.6 2 0 0 2 2 2 0 Poxvirus P35 protein PPR_2 PF13041.1 KOS13337.1 - 5.8e-05 22.9 0.0 0.00088 19.1 0.0 2.4 2 1 0 2 2 2 1 PPR repeat family PPR_1 PF12854.2 KOS13337.1 - 0.00062 19.1 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 KOS13337.1 - 0.014 15.6 2.2 0.064 13.5 0.0 3.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 KOS13337.1 - 0.016 15.1 0.0 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 PPR repeat DUF1768 PF08719.6 KOS13338.1 - 1.1e-32 112.9 0.0 1.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 KOS13338.1 - 0.016 14.7 0.0 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 MutL_C PF08676.6 KOS13340.1 - 6.2e-26 90.7 0.0 1.3e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KOS13340.1 - 1.2e-23 82.7 0.0 3.4e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KOS13340.1 - 6.9e-11 41.8 0.0 1.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS13340.1 - 6.3e-10 38.8 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_transf_21 PF13506.1 KOS13341.1 - 1.8e-20 72.9 0.2 5.7e-07 28.9 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KOS13341.1 - 2e-16 60.4 0.6 3.3e-16 59.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KOS13341.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 V-ATPase_G PF03179.10 KOS13342.1 - 1.9e-29 102.0 19.6 2.2e-29 101.8 13.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 KOS13342.1 - 0.00054 19.2 20.4 0.00063 19.0 14.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Clathrin_lg_ch PF01086.12 KOS13342.1 - 0.0042 17.0 12.9 0.005 16.7 9.0 1.1 1 0 0 1 1 1 1 Clathrin light chain SF-assemblin PF06705.6 KOS13342.1 - 0.0042 16.2 11.0 0.0052 15.9 7.6 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin ATP-synt_B PF00430.13 KOS13342.1 - 0.019 14.7 21.7 0.056 13.2 9.9 2.1 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Gti1_Pac2 PF09729.4 KOS13342.1 - 0.028 14.2 5.6 0.034 13.9 3.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family HrpE PF06188.7 KOS13342.1 - 0.045 13.5 7.3 0.054 13.2 5.1 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3435 PF11917.3 KOS13342.1 - 0.073 11.7 8.2 0.086 11.5 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) GTP_cyclohydro2 PF00925.15 KOS13342.1 - 0.11 11.7 1.0 0.14 11.3 0.5 1.4 1 1 0 1 1 1 0 GTP cyclohydrolase II TPR_20 PF14561.1 KOS13342.1 - 0.13 12.4 5.9 0.036 14.1 1.5 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apolipoprotein PF01442.13 KOS13342.1 - 0.17 11.3 11.2 0.33 10.4 7.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4272 PF14094.1 KOS13342.1 - 0.17 10.8 2.6 0.24 10.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) Sec8_exocyst PF04048.9 KOS13342.1 - 0.18 11.4 5.5 0.23 11.0 3.8 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF883 PF05957.8 KOS13342.1 - 0.19 12.1 8.7 0.43 11.0 4.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RRF PF01765.14 KOS13342.1 - 0.26 10.7 13.6 0.43 10.0 9.4 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Phage_int_SAM_5 PF13102.1 KOS13342.1 - 0.27 11.2 7.3 0.33 10.9 5.1 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF3826 PF12875.2 KOS13342.1 - 0.38 10.4 10.3 0.45 10.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF342 PF03961.8 KOS13342.1 - 0.51 8.6 9.5 0.57 8.5 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vps54 PF07928.7 KOS13342.1 - 0.93 9.6 3.0 22 5.1 2.1 2.2 1 1 0 1 1 1 0 Vps54-like protein She9_MDM33 PF05546.6 KOS13342.1 - 1.1 8.7 11.2 1.4 8.3 7.7 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family TMPIT PF07851.8 KOS13342.1 - 1.2 8.1 8.9 1.4 7.8 6.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein Iron_permease PF04120.7 KOS13342.1 - 1.2 8.7 5.6 1.6 8.2 3.2 1.7 1 1 1 2 2 2 0 Low affinity iron permease DUF4239 PF14023.1 KOS13342.1 - 1.5 8.1 3.3 2.9 7.2 2.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) YlqD PF11068.3 KOS13342.1 - 1.5 8.8 12.0 1.4 8.9 7.6 1.5 1 1 0 1 1 1 0 YlqD protein DUF4407 PF14362.1 KOS13342.1 - 1.6 7.6 8.4 2.2 7.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PTPlike_phytase PF14566.1 KOS13342.1 - 2.9 7.9 5.1 4.4 7.3 3.5 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate Phage_GPO PF05929.6 KOS13342.1 - 3 7.0 10.0 3.8 6.6 5.3 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase vATP-synt_E PF01991.13 KOS13342.1 - 3.1 7.0 21.7 14 4.9 15.0 1.7 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATP-synt_F6 PF05511.6 KOS13342.1 - 4.3 7.3 8.8 9 6.2 3.5 2.2 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Ribosomal_L28e PF01778.12 KOS13342.1 - 4.3 7.7 8.7 5.8 7.3 1.2 2.1 1 1 1 2 2 2 0 Ribosomal L28e protein family Effector_1 PF04518.7 KOS13342.1 - 9.7 5.0 11.6 0.76 8.7 0.6 2.0 1 1 1 2 2 2 0 Effector from type III secretion system Tropomyosin_1 PF12718.2 KOS13343.1 - 7.3e-45 152.3 35.2 8.8e-45 152.0 24.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KOS13343.1 - 2.2e-14 53.1 33.9 1.5e-06 27.5 8.1 3.0 1 1 2 3 3 3 3 Tropomyosin ERM PF00769.14 KOS13343.1 - 0.00043 19.9 20.3 0.00043 19.9 14.1 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Cast PF10174.4 KOS13343.1 - 0.0005 18.2 35.9 0.028 12.4 24.9 2.0 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone FliJ PF02050.11 KOS13343.1 - 0.0014 18.6 16.3 0.0014 18.6 11.3 2.2 1 1 1 2 2 2 1 Flagellar FliJ protein CCDC-167 PF15188.1 KOS13343.1 - 0.002 18.0 4.6 0.002 18.0 3.2 3.6 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 WEMBL PF05701.6 KOS13343.1 - 0.0044 15.5 33.5 0.085 11.3 10.1 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Striatin PF08232.7 KOS13343.1 - 0.0092 16.2 25.6 0.045 14.0 9.7 2.1 1 1 1 2 2 2 2 Striatin family DUF4200 PF13863.1 KOS13343.1 - 0.02 14.8 33.1 0.22 11.4 11.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 KOS13343.1 - 0.038 13.7 36.2 0.36 10.5 3.0 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KOS13343.1 - 0.044 13.5 37.6 0.43 10.4 8.8 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FliD_C PF07195.7 KOS13343.1 - 0.051 12.8 20.6 0.56 9.4 4.2 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus GAS PF13851.1 KOS13343.1 - 0.053 12.7 33.0 0.41 9.8 22.9 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 KOS13343.1 - 0.053 12.7 28.6 0.051 12.8 11.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WXG100 PF06013.7 KOS13343.1 - 0.057 13.4 15.3 1 9.3 0.8 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Clr5 PF14420.1 KOS13343.1 - 0.074 12.9 5.1 0.13 12.1 2.0 2.2 2 0 0 2 2 2 0 Clr5 domain Uds1 PF15456.1 KOS13343.1 - 0.092 12.7 29.4 0.12 12.3 9.3 2.1 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 KOS13343.1 - 0.11 12.0 37.8 0.29 10.7 8.3 2.0 1 1 1 2 2 2 0 IncA protein Fmp27_WPPW PF10359.4 KOS13343.1 - 0.12 10.8 26.5 0.41 9.0 4.9 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reo_sigmaC PF04582.7 KOS13343.1 - 0.14 11.2 8.0 0.48 9.5 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KOS13343.1 - 0.17 11.7 12.6 0.32 10.8 1.7 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 KOS13343.1 - 0.17 11.7 35.8 0.7 9.7 22.1 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 KOS13343.1 - 0.19 11.9 12.2 1.3 9.3 4.4 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 KOS13343.1 - 0.21 11.4 28.1 0.33 10.8 7.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 KOS13343.1 - 0.23 11.8 25.3 1.2 9.4 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 KOS13343.1 - 0.24 11.2 27.5 0.076 12.8 5.9 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Fib_alpha PF08702.5 KOS13343.1 - 0.24 11.5 21.0 0.78 9.8 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 KOS13343.1 - 0.3 8.3 32.4 0.071 10.4 11.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) EzrA PF06160.7 KOS13343.1 - 0.31 9.1 26.6 0.27 9.3 8.5 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.14 KOS13343.1 - 0.32 8.8 19.7 0.35 8.6 13.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_27 PF13514.1 KOS13343.1 - 0.4 8.3 30.0 0.65 7.5 20.8 1.4 1 1 0 1 1 1 0 AAA domain Laminin_I PF06008.9 KOS13343.1 - 0.6 9.3 27.0 1.1 8.5 5.5 2.1 1 1 1 2 2 2 0 Laminin Domain I ADIP PF11559.3 KOS13343.1 - 0.64 9.9 31.3 1.1 9.1 4.2 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KOS13343.1 - 0.67 10.2 35.7 5.3 7.4 6.2 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF904) DASH_Hsk3 PF08227.6 KOS13343.1 - 0.7 10.1 4.4 3.9 7.7 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like AAA_13 PF13166.1 KOS13343.1 - 0.72 8.2 22.8 0.93 7.8 15.8 1.2 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 KOS13343.1 - 0.79 8.5 16.7 0.019 13.8 5.0 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain PspA_IM30 PF04012.7 KOS13343.1 - 0.84 8.9 31.4 0.27 10.5 9.4 2.6 1 1 0 2 2 2 0 PspA/IM30 family THOC7 PF05615.8 KOS13343.1 - 0.89 9.8 26.9 0.037 14.2 9.3 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 Flagellin_C PF00700.16 KOS13343.1 - 0.92 9.7 6.1 0.61 10.2 0.9 2.6 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region DUF812 PF05667.6 KOS13343.1 - 0.96 7.8 28.2 3.3 6.0 19.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Laminin_II PF06009.7 KOS13343.1 - 0.98 9.1 20.1 0.73 9.5 5.4 2.6 1 1 1 2 2 2 0 Laminin Domain II DUF641 PF04859.7 KOS13343.1 - 1.1 9.0 20.4 0.65 9.7 3.0 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF2360 PF10152.4 KOS13343.1 - 1.2 9.3 12.9 0.88 9.8 2.0 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Lebercilin PF15619.1 KOS13343.1 - 1.4 8.2 32.7 1 8.7 9.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin PF02996.12 KOS13343.1 - 1.6 8.3 26.2 0.27 10.8 2.5 3.8 1 1 3 4 4 4 0 Prefoldin subunit Prefoldin_2 PF01920.15 KOS13343.1 - 1.8 8.3 32.4 2.5 7.8 0.9 3.9 1 1 2 3 3 3 0 Prefoldin subunit APG6 PF04111.7 KOS13343.1 - 1.8 7.5 36.3 0.22 10.5 15.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Sec2p PF06428.6 KOS13343.1 - 2 8.3 28.5 1.3 8.9 4.4 3.2 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF745 PF05335.8 KOS13343.1 - 2.4 7.6 24.8 0.18 11.3 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Cep57_CLD_2 PF14197.1 KOS13343.1 - 2.5 8.0 34.4 0.1 12.5 5.9 4.3 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 Occludin_ELL PF07303.8 KOS13343.1 - 3.1 8.5 21.2 6.7 7.4 3.2 3.7 1 1 3 4 4 4 0 Occludin homology domain IFT57 PF10498.4 KOS13343.1 - 3.6 6.2 26.5 6.5 5.3 5.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Borrelia_P83 PF05262.6 KOS13343.1 - 4 5.6 28.1 4.5 5.4 19.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Microtub_assoc PF07989.6 KOS13343.1 - 4 7.3 18.4 2.5 7.9 3.3 2.9 2 1 1 3 3 3 0 Microtubule associated TMF_TATA_bd PF12325.3 KOS13343.1 - 4.7 6.9 31.7 0.16 11.7 7.3 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Mvb12 PF09452.5 KOS13343.1 - 4.9 7.4 8.5 3 8.0 3.0 2.3 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF1664 PF07889.7 KOS13343.1 - 5.1 6.9 17.5 1.4 8.7 3.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YscO PF07321.7 KOS13343.1 - 5.5 6.8 34.0 3 7.6 9.0 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO Mnd1 PF03962.10 KOS13343.1 - 6.7 6.3 31.7 6.7 6.3 12.0 2.2 1 1 1 2 2 2 0 Mnd1 family Prominin PF05478.6 KOS13343.1 - 7.7 3.9 12.7 9 3.6 8.8 1.1 1 0 0 1 1 1 0 Prominin Adeno_PIX PF03955.9 KOS13343.1 - 8 7.0 18.7 5.2 7.6 2.5 3.0 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) Atg14 PF10186.4 KOS13343.1 - 8.1 5.2 28.4 2.7 6.8 10.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 KOS13343.1 - 8.1 6.6 22.7 9.9 6.3 6.8 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 KOS13343.1 - 8.9 5.7 29.2 0.29 10.5 10.2 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 UDPGP PF01704.13 KOS13344.1 - 3e-51 174.2 0.0 4.2e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase tRNA_bind PF01588.15 KOS13344.1 - 1.8e-27 95.0 0.0 3.3e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KOS13344.1 - 7.8e-06 26.2 0.0 2.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS13344.1 - 2.9e-05 23.8 0.0 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS13344.1 - 3.4e-05 23.7 0.0 9.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NTP_transf_3 PF12804.2 KOS13344.1 - 0.022 14.8 0.1 0.072 13.1 0.1 2.0 1 1 0 1 1 1 0 MobA-like NTP transferase domain AA_permease PF00324.16 KOS13345.1 - 6.8e-59 199.4 37.0 8.4e-59 199.1 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease GCV_T PF01571.16 KOS13346.1 - 2.9e-64 216.3 0.0 4.1e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KOS13346.1 - 8.3e-25 86.6 0.1 1.8e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KOS13346.1 - 7.4e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family IF-2B PF01008.12 KOS13347.1 - 1.1e-69 234.6 0.0 1.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HEAT_EZ PF13513.1 KOS13348.1 - 7e-27 93.1 14.7 3.8e-06 27.2 0.0 11.5 11 2 1 12 12 11 5 HEAT-like repeat HEAT_2 PF13646.1 KOS13348.1 - 1e-16 60.9 23.8 0.0005 20.2 0.0 8.4 6 3 5 11 11 10 5 HEAT repeats HEAT PF02985.17 KOS13348.1 - 2.8e-16 58.0 11.2 0.0018 18.1 0.0 11.2 13 0 0 13 13 12 3 HEAT repeat Ipi1_N PF12333.3 KOS13348.1 - 3.4e-10 39.8 0.5 0.016 15.1 0.0 6.6 5 1 1 6 6 6 2 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 KOS13348.1 - 8.1e-09 35.5 4.0 0.014 15.2 0.1 6.0 5 1 1 6 6 6 3 Exportin 1-like protein IBN_N PF03810.14 KOS13348.1 - 6.4e-07 29.1 1.1 8.9e-06 25.5 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KOS13348.1 - 1.9e-06 28.1 0.0 0.67 10.3 0.0 6.0 6 2 2 8 8 7 2 Vacuolar 14 Fab1-binding region UME PF08064.8 KOS13348.1 - 1.1e-05 25.3 0.0 0.12 12.3 0.0 4.8 5 1 0 5 5 5 1 UME (NUC010) domain MMS19_C PF12460.3 KOS13348.1 - 4.1e-05 22.4 4.1 0.2 10.3 1.1 5.3 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KOS13348.1 - 6.6e-05 22.3 0.3 0.41 9.9 0.0 4.3 4 1 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.15 KOS13348.1 - 0.0005 18.5 3.2 0.87 7.8 0.3 3.8 3 1 0 3 3 3 2 Adaptin N terminal region MMS19_N PF14500.1 KOS13348.1 - 0.0018 17.5 2.2 0.083 12.1 0.4 3.9 3 2 2 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.2 KOS13348.1 - 0.002 18.0 0.2 5 7.1 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion ParcG PF10274.4 KOS13348.1 - 0.011 15.5 0.5 3.4 7.5 0.1 3.8 3 1 0 3 3 3 0 Parkin co-regulated protein Cnd1 PF12717.2 KOS13348.1 - 0.015 15.1 0.0 25 4.6 0.0 4.4 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.3 KOS13348.1 - 0.057 13.1 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Trp_syntA PF00290.15 KOS13349.1 - 2.6e-86 288.3 0.0 4.7e-86 287.5 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KOS13349.1 - 5.3e-43 147.3 0.4 1e-42 146.4 0.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAD_binding_1 PF00667.15 KOS13350.1 - 4.8e-49 166.7 0.0 8e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KOS13350.1 - 5.6e-07 30.0 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ThiF PF00899.16 KOS13351.1 - 6.3e-50 168.5 0.1 2.2e-30 105.2 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 KOS13351.1 - 6.2e-44 149.1 0.1 1.2e-43 148.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KOS13351.1 - 4.5e-36 122.2 1.5 1.7e-25 88.3 0.1 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KOS13351.1 - 4.6e-26 89.9 0.5 3.3e-22 77.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Cpn10 PF00166.16 KOS13351.1 - 0.11 12.3 0.1 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 Chaperonin 10 Kd subunit PapD-like PF14874.1 KOS13352.1 - 2.1e-05 24.3 0.1 0.033 14.1 0.1 4.5 6 0 0 6 6 6 1 Flagellar-associated PapD-like Peptidase_M1 PF01433.15 KOS13353.1 - 0 1283.9 1.8 1e-101 340.8 0.1 8.2 4 4 0 4 4 4 4 Peptidase family M1 ERAP1_C PF11838.3 KOS13353.1 - 3.9e-221 732.8 23.6 3.5e-59 200.6 0.3 4.2 4 0 0 4 4 4 4 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KOS13353.1 - 4.7e-60 201.2 14.1 2.5e-16 59.8 0.3 5.1 4 0 0 4 4 4 4 Peptidase MA superfamily Imm16 PF15565.1 KOS13353.1 - 0.028 14.2 1.6 7.6 6.4 0.0 3.2 2 0 0 2 2 2 0 Immunity protein 16 BolA PF01722.13 KOS13354.1 - 1.2e-18 66.8 0.0 1.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein Ribosomal_60s PF00428.14 KOS13354.1 - 0.21 11.9 2.1 0.52 10.7 1.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein UvrD-helicase PF00580.16 KOS13355.1 - 8.6e-14 51.5 0.0 6.4e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 KOS13355.1 - 5.6e-07 29.3 0.0 0.00069 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS13355.1 - 7.6e-06 25.5 0.1 3.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 KOS13355.1 - 5.8e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 KOS13355.1 - 0.00013 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 KOS13355.1 - 0.00017 20.9 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 KOS13355.1 - 0.00048 19.7 0.0 0.042 13.3 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KOS13355.1 - 0.027 14.5 0.0 3.6 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Gaa1 PF04114.9 KOS13356.1 - 1.7e-46 158.9 13.2 2.7e-25 89.0 0.1 3.5 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SET PF00856.23 KOS13357.1 - 3.5e-11 43.6 2.0 5.3e-10 39.8 0.0 3.4 3 1 0 3 3 3 1 SET domain PHD PF00628.24 KOS13357.1 - 5e-07 29.3 15.6 8.9e-07 28.5 10.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KOS13357.1 - 0.0066 15.7 7.3 0.014 14.7 5.1 1.5 1 0 0 1 1 1 1 PHD-finger Nsp1_C PF05064.8 KOS13358.1 - 5e-33 113.2 0.8 1.1e-32 112.1 0.5 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KOS13358.1 - 4.9e-14 52.5 197.0 1.3e-05 25.3 27.6 5.6 1 1 4 5 5 5 3 Nucleoporin FG repeat region LTXXQ PF07813.7 KOS13358.1 - 0.0037 17.6 5.8 0.012 16.0 4.1 1.9 1 1 0 1 1 1 1 LTXXQ motif family protein HAUS-augmin3 PF14932.1 KOS13358.1 - 0.015 14.5 1.7 0.026 13.7 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4201 PF13870.1 KOS13358.1 - 0.1 12.0 3.9 0.079 12.3 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 KOS13358.1 - 0.11 12.0 3.3 0.26 10.8 1.8 1.8 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 KOS13358.1 - 0.2 10.8 2.9 0.34 10.0 2.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF607 PF04678.8 KOS13358.1 - 0.46 10.3 1.7 4.2 7.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 ELYS PF13934.1 KOS13359.1 - 8e-16 58.4 0.1 1.1e-14 54.7 0.0 2.3 2 0 0 2 2 2 1 Nuclear pore complex assembly Snf7 PF03357.16 KOS13360.1 - 2.1e-31 108.5 10.8 2.4e-31 108.4 7.5 1.0 1 0 0 1 1 1 1 Snf7 DUF2267 PF10025.4 KOS13360.1 - 0.043 13.8 7.6 0.05 13.6 3.9 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Bac_GDH PF05088.7 KOS13360.1 - 0.12 9.7 7.4 0.14 9.5 5.1 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase FemAB PF02388.11 KOS13360.1 - 0.15 10.7 4.0 0.18 10.4 2.8 1.1 1 0 0 1 1 1 0 FemAB family zf-C4H2 PF10146.4 KOS13360.1 - 0.18 11.7 5.4 0.095 12.7 2.1 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein Ino80_Iec3 PF14612.1 KOS13360.1 - 3 7.8 9.4 3.5 7.6 2.6 2.0 1 1 1 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling SRPRB PF09439.5 KOS13361.1 - 1.2e-13 50.6 0.0 2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KOS13361.1 - 1.9e-09 37.0 0.0 3.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS13361.1 - 0.00013 21.8 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS13361.1 - 0.00086 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS13361.1 - 0.023 15.2 0.0 0.078 13.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KOS13361.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.17 KOS13361.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ras family G-alpha PF00503.15 KOS13361.1 - 0.13 10.8 0.1 2.7 6.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Glyco_hydro_cc PF11790.3 KOS13362.1 - 5.8e-59 199.3 6.3 1e-58 198.6 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.12 KOS13362.1 - 0.0035 16.3 0.2 0.006 15.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Hid1 PF12722.2 KOS13362.1 - 0.47 8.0 8.9 0.69 7.5 6.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ashwin PF15323.1 KOS13362.1 - 4.7 7.1 19.1 7.1 6.5 13.3 1.3 1 0 0 1 1 1 0 Developmental protein Sec3_C PF09763.4 KOS13362.1 - 7.5 4.5 10.7 10 4.1 7.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RhoGAP PF00620.22 KOS13363.1 - 1.4e-22 79.9 0.0 3.7e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 RhoGAP domain Tho2 PF11262.3 KOS13364.1 - 2.7e-64 217.0 0.5 5.4e-64 216.1 0.0 1.7 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KOS13364.1 - 2.5e-29 100.8 0.0 6.2e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF853 PF05872.7 KOS13364.1 - 0.098 10.9 5.2 0.19 10.0 3.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Ycf1 PF05758.7 KOS13364.1 - 0.79 7.3 1.2 1.2 6.7 0.9 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 KOS13364.1 - 9.1 3.8 3.3 16 2.9 2.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RabGAP-TBC PF00566.13 KOS13365.1 - 1.1e-14 54.4 0.1 2.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Clat_adaptor_s PF01217.15 KOS13365.1 - 2.7e-13 49.8 0.0 6.9e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Abhydrolase_3 PF07859.8 KOS13366.1 - 7.5e-22 77.9 0.2 2.5e-21 76.2 0.0 1.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS13366.1 - 3.5e-19 68.6 0.0 8.3e-17 60.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS13366.1 - 0.022 14.5 0.0 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS13366.1 - 0.038 13.2 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.27 KOS13367.1 - 8.7e-20 69.8 17.0 1.4e-07 31.0 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 KOS13367.1 - 2.4e-07 30.7 1.6 5.4 7.4 0.0 5.2 4 0 0 4 4 4 3 PQQ-like domain DUF3312 PF11768.3 KOS13367.1 - 0.0076 14.5 0.0 0.03 12.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) DUF2415 PF10313.4 KOS13367.1 - 0.14 11.8 0.3 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Adap_comp_sub PF00928.16 KOS13368.1 - 3.3e-39 134.5 0.0 4.4e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS13368.1 - 0.0049 16.5 0.1 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF5 PF04855.7 KOS13369.1 - 9.4e-54 182.4 1.7 8.1e-50 169.5 0.9 2.8 2 1 0 2 2 2 2 SNF5 / SMARCB1 / INI1 AT_hook PF02178.14 KOS13369.1 - 0.022 14.3 4.0 0.071 12.8 2.7 1.9 1 0 0 1 1 1 0 AT hook motif ADH_N PF08240.7 KOS13370.1 - 3.8e-27 94.2 0.7 7.4e-27 93.2 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS13370.1 - 6.3e-22 77.5 0.0 1.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS13370.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KOS13370.1 - 0.073 12.6 0.3 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain EFP PF01132.15 KOS13370.1 - 0.11 12.2 0.1 0.69 9.6 0.2 2.0 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain TrkA_N PF02254.13 KOS13370.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Mito_carr PF00153.22 KOS13371.1 - 1.1e-64 214.1 4.9 1.9e-23 81.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein THUMP PF02926.12 KOS13372.1 - 9.9e-14 51.4 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 THUMP domain EAP30 PF04157.11 KOS13373.1 - 1.2e-27 96.5 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KOS13373.1 - 5.3e-22 77.4 0.0 9.9e-22 76.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KOS13373.1 - 0.00016 20.6 3.0 0.00016 20.6 2.1 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KOS13373.1 - 0.016 15.0 12.5 0.029 14.1 2.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KOS13373.1 - 0.17 11.1 8.8 0.21 10.8 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain CHCH PF06747.8 KOS13374.1 - 1.9e-09 37.1 1.4 2.8e-09 36.6 1.0 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KOS13374.1 - 0.0034 17.3 0.8 0.0056 16.6 0.5 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KOS13374.1 - 0.086 12.8 0.7 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 KOS13374.1 - 0.095 12.4 1.7 0.15 11.8 1.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Tim17 PF02466.14 KOS13375.1 - 1.1e-12 48.1 11.7 1.6e-12 47.5 8.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bac_export_3 PF01313.14 KOS13375.1 - 1.2 8.9 3.1 17 5.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Gly-zipper_OmpA PF13436.1 KOS13375.1 - 1.7 8.3 17.6 4.3 7.0 6.6 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain TraT PF05818.7 KOS13375.1 - 3 7.2 11.6 2.8 7.3 0.5 2.1 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein NPR3 PF03666.8 KOS13376.1 - 2.8e-60 204.1 3.0 9.7e-48 162.8 0.0 3.1 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KOS13376.1 - 0.0025 16.5 0.3 0.49 9.0 0.0 2.4 2 0 0 2 2 2 2 Nitrogen permease regulator 2 Vps39_1 PF10366.4 KOS13377.1 - 1.3e-22 79.7 0.0 6.2e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KOS13377.1 - 2.3e-22 79.2 0.2 2e-20 72.9 0.1 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KOS13377.1 - 4.6e-06 26.2 0.0 6.1e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KOS13377.1 - 0.00019 21.0 0.0 0.26 10.8 0.0 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS PCI PF01399.22 KOS13378.1 - 2.4e-05 24.6 0.0 5.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KOS13378.1 - 0.11 12.3 0.0 0.45 10.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13378.1 - 0.12 12.0 1.8 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Drf_GBD PF06371.8 KOS13379.1 - 2.4e-10 40.0 0.0 3.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Thr_synth_N PF14821.1 KOS13380.1 - 4.9e-28 96.9 0.0 8.4e-27 93.0 0.0 2.5 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KOS13380.1 - 2.9e-18 66.1 0.0 6.2e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_7 PF13508.1 KOS13381.1 - 1.5e-07 31.4 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS13381.1 - 9.3e-07 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mss4 PF04421.8 KOS13381.1 - 4.7e-06 26.3 0.1 0.044 13.6 0.0 2.5 2 0 0 2 2 2 2 Mss4 protein Mec-17 PF05301.6 KOS13381.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 FR47 PF08445.5 KOS13381.1 - 0.034 13.8 0.0 0.094 12.4 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 KOS13381.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fork_head PF00250.13 KOS13382.1 - 1.6e-16 60.1 0.6 5.8e-16 58.3 0.1 2.0 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 KOS13382.1 - 0.00047 20.2 0.0 0.0027 17.7 0.0 2.2 1 1 0 1 1 1 1 FHA domain Gag_p10 PF02337.12 KOS13382.1 - 0.08 12.7 0.4 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Retroviral GAG p10 protein zf-MYND PF01753.13 KOS13383.1 - 2.8e-07 30.2 15.1 2.8e-07 30.2 10.5 3.1 2 1 0 2 2 2 1 MYND finger SET PF00856.23 KOS13383.1 - 1.1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 SET domain Methyltransf_8 PF05148.10 KOS13384.1 - 1.9e-45 155.1 0.0 4.4e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 KOS13384.1 - 0.0071 16.0 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CcmD PF04995.9 KOS13384.1 - 0.034 13.8 1.6 0.12 12.0 1.1 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Methyltransf_11 PF08241.7 KOS13384.1 - 0.063 13.7 0.0 0.22 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain UPF0113 PF03657.8 KOS13385.1 - 1.6e-12 47.3 0.0 2e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Ribosomal_L11_N PF03946.9 KOS13386.1 - 1.3e-24 85.4 1.5 5.6e-24 83.3 0.2 2.4 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KOS13386.1 - 2.9e-23 81.7 1.1 4.8e-23 81.0 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NifU_N PF01592.11 KOS13387.1 - 5.4e-52 175.0 0.1 7.3e-52 174.6 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Hydrolase_6 PF13344.1 KOS13388.1 - 1.4e-28 98.7 0.0 2.7e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS13388.1 - 3.1e-16 58.8 0.0 7.6e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KOS13388.1 - 1.2e-09 38.8 0.0 2e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS13388.1 - 2.7e-08 34.2 0.0 6.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KOS13388.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HSP70 PF00012.15 KOS13389.1 - 1.2e-273 908.6 5.9 1.3e-273 908.4 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS13389.1 - 1.7e-15 56.4 0.1 4.7e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DUF4582 PF15189.1 KOS13389.1 - 0.033 13.4 0.1 0.082 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Hydantoinase_A PF01968.13 KOS13389.1 - 0.044 12.8 1.2 0.076 12.1 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 KOS13389.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 KOS13389.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 KOS13389.1 - 0.1 12.4 4.6 1 9.2 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA HAD PF12710.2 KOS13390.1 - 6.9e-14 52.4 0.1 9.1e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KOS13390.1 - 1.4e-07 31.0 0.0 3e-06 26.7 0.0 2.1 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 KOS13390.1 - 0.00011 22.5 0.2 0.00053 20.2 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KOS13390.1 - 0.03 13.4 0.2 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase PF00702.21 KOS13390.1 - 0.28 11.5 2.1 1.4 9.2 0.0 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_cc PF11790.3 KOS13391.1 - 3.3e-61 206.7 7.3 4.3e-61 206.3 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF837 PF05769.6 KOS13392.1 - 9.7e-07 28.4 7.3 1.7e-06 27.6 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF837) RNase_E_G PF10150.4 KOS13392.1 - 0.019 14.1 1.7 0.032 13.4 0.8 1.6 1 1 1 2 2 2 0 Ribonuclease E/G family DivIVA PF05103.8 KOS13392.1 - 0.059 13.4 8.0 0.76 9.8 2.7 2.5 2 1 0 2 2 2 0 DivIVA protein DivIC PF04977.10 KOS13392.1 - 0.098 12.1 8.3 4.8 6.7 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator SlyX PF04102.7 KOS13392.1 - 0.11 12.9 10.2 0.69 10.3 0.1 3.2 4 0 0 4 4 3 0 SlyX Bacillus_HBL PF05791.6 KOS13392.1 - 0.13 11.6 3.2 1.1 8.6 1.9 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 KOS13392.1 - 0.14 11.3 12.0 0.34 10.0 6.6 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 KOS13392.1 - 0.15 11.4 2.3 5.9 6.3 0.0 2.8 3 0 0 3 3 3 0 B-cell receptor-associated protein 31-like Med21 PF11221.3 KOS13392.1 - 0.16 11.9 4.8 0.39 10.6 0.5 3.0 3 0 0 3 3 3 0 Subunit 21 of Mediator complex HR1 PF02185.11 KOS13392.1 - 0.17 11.6 0.3 0.17 11.6 0.2 2.7 3 0 0 3 3 3 0 Hr1 repeat IFT20 PF14931.1 KOS13392.1 - 0.2 11.5 9.1 1.3 8.8 0.1 3.4 3 1 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF641 PF04859.7 KOS13392.1 - 0.21 11.3 4.2 1.4 8.6 0.1 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Lectin_N PF03954.9 KOS13392.1 - 0.31 10.4 4.7 0.13 11.6 1.6 1.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Lebercilin PF15619.1 KOS13392.1 - 0.45 9.8 13.0 21 4.4 7.1 3.0 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Kinetocho_Slk19 PF12709.2 KOS13392.1 - 0.53 10.3 9.9 12 6.0 0.1 3.9 3 1 1 4 4 4 0 Central kinetochore-associated Herpes_BLRF2 PF05812.7 KOS13392.1 - 0.58 9.9 0.1 0.58 9.9 0.0 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein Med9 PF07544.8 KOS13392.1 - 0.6 9.8 5.6 8.5 6.1 0.5 3.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.13 KOS13392.1 - 0.71 9.6 10.2 7.4 6.3 0.1 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper MscS_porin PF12795.2 KOS13392.1 - 0.93 8.7 12.1 3.7 6.7 8.5 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF972 PF06156.8 KOS13392.1 - 1.1 9.6 12.3 7.4 6.9 1.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FlxA PF14282.1 KOS13392.1 - 1.3 9.0 5.8 5.5 6.9 4.0 2.0 1 1 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.15 KOS13392.1 - 1.3 8.8 10.9 1.6 8.4 0.1 3.5 4 0 0 4 4 3 0 Prefoldin subunit CENP-Q PF13094.1 KOS13392.1 - 3 7.8 14.3 6.5 6.7 4.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 KOS13392.1 - 4.2 6.8 10.6 3.3 7.2 3.0 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 KOS13392.1 - 4.8 7.2 10.1 17 5.4 0.1 3.7 4 0 0 4 4 4 0 bZIP transcription factor IncA PF04156.9 KOS13392.1 - 5.3 6.5 13.1 21 4.6 0.0 2.7 1 1 1 2 2 2 0 IncA protein YlqD PF11068.3 KOS13392.1 - 6.8 6.7 7.3 3.6 7.6 3.2 1.9 1 1 2 3 3 3 0 YlqD protein MFS_1 PF07690.11 KOS13393.1 - 3.7e-19 68.6 57.3 9.4e-16 57.4 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.17 KOS13394.1 - 4e-13 49.4 0.0 1.8e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Toxin_22 PF08092.6 KOS13394.1 - 0.073 12.9 1.5 0.15 11.9 1.0 1.6 1 0 0 1 1 1 0 Magi peptide toxin family FHA PF00498.21 KOS13395.1 - 9.2e-17 60.9 0.0 4.5e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain Phage_Mu_Gam PF07352.7 KOS13395.1 - 0.11 11.9 1.8 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Atg14 PF10186.4 KOS13395.1 - 0.14 11.0 1.1 7.8 5.3 0.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 KOS13395.1 - 0.15 10.2 7.7 0.31 9.2 3.4 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DivIC PF04977.10 KOS13395.1 - 0.21 11.0 0.9 6.3 6.3 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KOS13395.1 - 0.23 11.7 2.5 1.3 9.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 KOS13395.1 - 0.29 10.8 12.7 0.029 14.0 1.8 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KOS13395.1 - 0.41 10.4 4.8 1.1 9.1 0.7 2.4 2 0 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 KOS13395.1 - 0.64 9.5 5.5 0.34 10.4 0.7 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KOS13395.1 - 0.67 9.7 2.6 2 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KOS13395.1 - 2.1 6.9 6.0 0.92 8.0 1.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KOS13395.1 - 2.9 7.7 7.6 8.3 6.2 0.6 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KOS13395.1 - 4.4 7.1 5.9 0.61 9.9 0.2 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 S-AdoMet_synt_C PF02773.11 KOS13396.1 - 3e-74 247.2 0.3 6.7e-74 246.1 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KOS13396.1 - 4.9e-48 162.0 0.0 9.4e-48 161.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KOS13396.1 - 2.5e-45 152.7 0.1 5e-45 151.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain BOP1NT PF08145.7 KOS13397.1 - 2.3e-104 348.7 0.7 3.4e-104 348.1 0.5 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KOS13397.1 - 6.1e-35 117.8 9.2 6.7e-09 35.2 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat CDC45 PF02724.9 KOS13397.1 - 4.9 5.0 12.3 7.3 4.4 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-6 PF01912.13 KOS13398.1 - 1.2e-83 279.0 0.5 1.5e-83 278.7 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family Ribosomal_L38e PF01781.13 KOS13399.1 - 2.7e-33 113.5 1.4 3.2e-33 113.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pex14_N PF04695.8 KOS13400.1 - 0.083 12.9 1.1 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 KOS13400.1 - 0.31 11.3 2.5 0.33 11.2 1.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 KOS13400.1 - 0.66 9.3 8.3 0.62 9.3 5.8 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KOS13400.1 - 1.7 6.7 5.6 1.7 6.8 3.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rab5ip PF07019.7 KOS13401.1 - 1e-08 35.1 6.6 1.7e-07 31.2 0.7 2.1 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) DUF2456 PF10445.4 KOS13401.1 - 1.1 9.1 6.9 1 9.3 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) FAD_binding_6 PF00970.19 KOS13403.1 - 1.9e-11 43.9 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KOS13403.1 - 3.5e-09 36.9 0.2 7.7e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 KOS13403.1 - 4.6e-08 33.5 0.0 8.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KOS13403.1 - 0.0019 18.1 0.1 0.008 16.1 0.1 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KOS13403.1 - 0.0091 15.6 0.2 0.05 13.2 0.2 2.0 1 1 0 1 1 1 1 Protoglobin Flg_hook PF02120.11 KOS13403.1 - 0.056 13.1 1.2 0.8 9.4 0.1 2.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK MoCF_biosynth PF00994.19 KOS13403.1 - 0.1 12.0 0.4 13 5.1 0.0 2.6 2 1 0 2 2 2 0 Probable molybdopterin binding domain MFS_1 PF07690.11 KOS13404.1 - 3.1e-06 26.1 11.3 2.8e-05 23.0 7.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4064 PF13273.1 KOS13404.1 - 0.21 11.6 2.0 1.4 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) RRM_1 PF00076.17 KOS13405.1 - 4.2e-13 48.7 0.0 1.6e-05 24.4 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13405.1 - 4.2e-11 42.5 0.0 0.00022 20.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13405.1 - 6.5e-11 42.0 0.0 0.00011 22.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS13405.1 - 0.04 13.6 0.0 1.6 8.4 0.0 2.5 2 1 0 2 2 2 0 Limkain b1 DUF1866 PF08952.6 KOS13405.1 - 0.055 13.0 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Ribosomal_S25 PF03297.10 KOS13406.1 - 3.8e-39 132.9 1.7 7.7e-39 131.9 1.2 1.5 1 0 0 1 1 1 1 S25 ribosomal protein PulS_OutS PF09691.5 KOS13406.1 - 0.058 13.4 0.4 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) PI3_PI4_kinase PF00454.22 KOS13408.1 - 5.2e-31 107.9 0.0 1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KOS13408.1 - 0.0026 17.4 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 KOS13408.1 - 0.0065 15.6 0.1 0.014 14.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) GTP_EFTU PF00009.22 KOS13409.1 - 2.9e-44 150.7 0.0 4.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS13409.1 - 8.1e-25 86.8 0.0 8.1e-25 86.8 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS13409.1 - 3e-09 36.8 0.4 8.8e-09 35.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS13409.1 - 0.00018 21.4 0.0 0.00064 19.6 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FAT PF02259.18 KOS13410.1 - 7.2e-70 235.7 7.0 7.2e-70 235.7 4.8 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KOS13410.1 - 9.9e-20 70.9 0.1 4.7e-19 68.7 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KOS13410.1 - 0.0023 17.3 0.3 0.0061 15.9 0.2 1.8 1 0 0 1 1 1 1 FATC domain PRKCSH-like PF12999.2 KOS13411.1 - 3.8e-52 176.3 5.2 6.5e-52 175.6 3.3 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KOS13411.1 - 6.9e-29 100.3 0.1 6.9e-29 100.3 0.1 2.0 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KOS13411.1 - 2.1e-09 38.0 1.3 5.2e-09 36.7 0.5 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein IncA PF04156.9 KOS13411.1 - 0.0045 16.6 3.1 2.2 7.8 2.8 2.2 2 0 0 2 2 2 2 IncA protein Ldl_recept_a PF00057.13 KOS13411.1 - 0.079 12.8 15.5 0.17 11.8 0.2 2.9 3 1 0 3 3 3 0 Low-density lipoprotein receptor domain class A HrpB7 PF09486.5 KOS13411.1 - 0.093 12.6 12.3 2.6 7.9 0.3 3.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) TFIIF_beta PF02270.10 KOS13412.1 - 3.4e-56 191.0 0.0 1.1e-55 189.4 0.0 1.7 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 KOS13412.1 - 0.097 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 IS66 C-terminal element DUF947 PF06102.7 KOS13413.1 - 5.4e-41 140.2 15.2 5.4e-41 140.2 10.6 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF947) Myb_DNA-binding PF00249.26 KOS13414.1 - 4.9e-29 100.1 16.1 4.2e-13 49.1 0.1 6.1 6 0 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS13414.1 - 4.4e-24 84.3 2.9 2.5e-11 43.5 0.0 5.0 4 2 2 6 6 6 4 Myb-like DNA-binding domain DUF3606 PF12244.3 KOS13414.1 - 0.00035 20.1 0.2 0.076 12.6 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3606) Rap1_C PF11626.3 KOS13414.1 - 0.0006 19.6 6.2 2.2 8.2 0.3 4.5 3 1 1 4 4 4 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Jag_N PF14804.1 KOS13414.1 - 0.33 11.0 2.2 14 5.7 0.0 3.5 3 1 1 4 4 4 0 Jag N-terminus Myb_DNA-bind_4 PF13837.1 KOS13414.1 - 0.36 10.9 13.9 0.51 10.5 0.2 5.5 4 3 0 5 5 5 0 Myb/SANT-like DNA-binding domain DUF1488 PF07369.6 KOS13414.1 - 0.4 10.5 3.5 0.82 9.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) HOOK PF05622.7 KOS13415.1 - 2.7e-06 25.5 59.8 0.0046 14.8 7.1 3.8 1 1 2 3 3 3 3 HOOK protein AAA_13 PF13166.1 KOS13415.1 - 0.00047 18.7 26.5 0.00047 18.7 18.4 2.3 2 0 0 2 2 2 1 AAA domain DUF904 PF06005.7 KOS13415.1 - 0.0072 16.5 7.4 0.0072 16.5 5.1 6.1 3 2 2 5 5 5 1 Protein of unknown function (DUF904) IncA PF04156.9 KOS13415.1 - 0.06 12.9 64.7 0.054 13.0 12.3 4.0 2 2 2 4 4 4 0 IncA protein TPR_MLP1_2 PF07926.7 KOS13415.1 - 0.22 11.2 60.5 3 7.6 0.1 5.8 3 1 2 5 5 5 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 KOS13415.1 - 0.23 11.4 0.1 0.18 11.7 4.4 7.0 4 1 3 8 8 8 0 bZIP transcription factor BPL_LplA_LipB PF03099.14 KOS13416.1 - 3.2e-14 53.0 0.0 5.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 KOS13416.1 - 7.1e-08 31.6 0.0 2.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal CDT1 PF08839.6 KOS13418.1 - 4.1e-05 23.5 0.0 0.15 11.9 0.0 2.8 2 1 0 2 2 2 2 DNA replication factor CDT1 like PH PF00169.24 KOS13418.1 - 0.0045 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Arm PF00514.18 KOS13419.1 - 3.3 7.6 18.2 1.4 8.8 0.0 6.5 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat BTB PF00651.26 KOS13420.1 - 1.9e-05 24.6 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF913 PF06025.7 KOS13421.1 - 2.1e-67 227.5 0.5 9.1e-64 215.5 0.0 4.2 2 1 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KOS13421.1 - 6.8e-51 173.5 0.0 1.9e-50 172.0 0.0 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) UBA PF00627.26 KOS13421.1 - 3.3e-10 39.5 0.0 9.2e-10 38.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF4414 PF14377.1 KOS13421.1 - 7e-08 32.3 5.2 1.2e-07 31.6 1.8 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) RabGAP-TBC PF00566.13 KOS13422.1 - 2.4e-24 86.0 7.8 9.6e-18 64.4 1.5 3.1 3 0 0 3 3 3 3 Rab-GTPase-TBC domain Acyltransferase PF01553.16 KOS13423.1 - 1.2e-32 112.1 0.0 1.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 KOS13424.1 - 8.8e-53 179.0 0.0 1.3e-45 155.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13424.1 - 4.4e-22 78.3 0.0 1.3e-18 66.9 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS13424.1 - 4.2e-07 29.2 0.0 1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13424.1 - 0.0018 18.0 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS13424.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KOS13424.1 - 0.052 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RasGAP_C PF03836.10 KOS13425.1 - 1.3e-12 47.6 4.4 1.6e-12 47.3 3.1 1.0 1 0 0 1 1 1 1 RasGAP C-terminus CENP-F_leu_zip PF10473.4 KOS13425.1 - 0.015 15.1 4.1 0.018 14.9 2.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.7 KOS13425.1 - 0.024 14.6 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 KOS13425.1 - 0.03 14.0 1.7 0.03 14.0 1.2 1.7 1 1 0 1 1 1 0 Prefoldin subunit DUF2528 PF10800.3 KOS13425.1 - 0.033 14.5 0.1 0.041 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Adeno_PIX PF03955.9 KOS13425.1 - 0.042 14.3 0.5 0.057 13.9 0.3 1.2 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Sec8_exocyst PF04048.9 KOS13425.1 - 0.073 12.6 1.8 0.11 12.1 1.1 1.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain TBPIP PF07106.8 KOS13425.1 - 0.1 12.1 3.1 0.12 11.9 2.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 KOS13425.1 - 0.14 11.9 1.6 0.44 10.3 0.4 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF4200 PF13863.1 KOS13425.1 - 0.22 11.4 5.8 1 9.3 4.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 KOS13425.1 - 0.87 9.1 3.7 1.1 8.7 2.6 1.3 1 1 0 1 1 1 0 IncA protein WD40 PF00400.27 KOS13426.1 - 6.4e-53 174.8 11.9 9.7e-11 41.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS13426.1 - 0.00098 17.3 1.7 1.3 7.1 0.1 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KOS13426.1 - 0.019 14.4 0.4 4.2 6.7 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain BORG_CEP PF14957.1 KOS13426.1 - 5.8 7.8 11.8 3.6 8.5 4.3 2.3 2 0 0 2 2 2 0 Cdc42 effector cNMP_binding PF00027.24 KOS13427.1 - 9.6e-42 140.7 0.0 1.7e-20 72.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Mt_ATP-synt_D PF05873.7 KOS13427.1 - 2e-12 47.0 0.8 3.5e-12 46.2 0.6 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) AAA_13 PF13166.1 KOS13427.1 - 0.042 12.3 1.1 0.059 11.8 0.7 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 KOS13427.1 - 0.43 8.0 1.5 0.58 7.6 1.0 1.1 1 0 0 1 1 1 0 Prominin PfkB PF00294.19 KOS13428.1 - 9.3e-39 133.3 0.1 1.1e-38 133.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Metallophos PF00149.23 KOS13429.1 - 1.8e-11 43.8 1.7 4.1e-11 42.6 1.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS13429.1 - 0.0034 17.2 0.2 0.0097 15.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cullin PF00888.17 KOS13430.1 - 4.2e-60 203.9 0.0 8.5e-60 202.9 0.0 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KOS13430.1 - 1e-13 50.8 1.7 2e-13 49.9 1.2 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain COX5A PF02284.11 KOS13430.1 - 0.085 12.8 0.2 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Utp14 PF04615.8 KOS13431.1 - 1.9e-154 515.7 47.2 1.4e-90 304.5 26.7 2.3 2 1 1 3 3 3 2 Utp14 protein RinB PF06116.7 KOS13431.1 - 0.31 10.6 3.2 1.1 8.9 2.2 2.0 1 0 0 1 1 1 0 Transcriptional activator RinB Rad9 PF04139.8 KOS13432.1 - 7e-37 126.9 0.0 1.2e-36 126.1 0.0 1.3 2 0 0 2 2 2 1 Rad9 WD40 PF00400.27 KOS13433.1 - 0.00017 21.3 0.3 0.00052 19.8 0.2 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat F-box-like PF12937.2 KOS13433.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like AAA_2 PF07724.9 KOS13435.1 - 4.3e-53 179.7 0.0 7.2e-50 169.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KOS13435.1 - 7.7e-27 94.0 0.0 2.1e-14 53.8 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KOS13435.1 - 1.2e-20 73.1 0.0 5.8e-20 70.9 0.0 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KOS13435.1 - 3.2e-15 56.0 0.0 4.2e-09 36.2 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 KOS13435.1 - 3.9e-14 52.3 3.9 6.9e-07 29.0 0.0 3.8 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 KOS13435.1 - 1.3e-12 48.1 12.0 1.6e-06 28.2 0.0 6.1 5 3 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 KOS13435.1 - 4.9e-10 39.6 3.9 0.0065 16.6 0.0 5.7 4 2 1 5 5 4 2 AAA domain Sigma54_activat PF00158.21 KOS13435.1 - 3.8e-08 32.9 0.0 4.7e-06 26.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KOS13435.1 - 6.1e-06 27.0 4.7 0.84 10.4 3.0 4.3 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KOS13435.1 - 9.6e-06 25.1 0.0 0.051 13.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KOS13435.1 - 1.7e-05 23.9 0.0 0.013 14.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 KOS13435.1 - 1.9e-05 24.7 0.0 0.3 11.2 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.1 KOS13435.1 - 2e-05 24.4 0.0 0.14 12.0 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS13435.1 - 8.8e-05 22.1 0.1 0.084 12.6 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 KOS13435.1 - 0.00021 20.5 0.0 0.21 10.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KOS13435.1 - 0.0003 20.7 0.8 0.21 11.5 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KOS13435.1 - 0.00033 20.9 3.1 0.38 11.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.7 KOS13435.1 - 0.0012 17.9 0.0 0.45 9.5 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KOS13435.1 - 0.0014 18.2 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KOS13435.1 - 0.002 17.8 8.1 0.0046 16.6 0.0 4.1 4 2 1 5 5 4 1 Archaeal ATPase Torsin PF06309.6 KOS13435.1 - 0.0021 17.9 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Torsin T2SE PF00437.15 KOS13435.1 - 0.0022 16.9 0.0 0.039 12.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KOS13435.1 - 0.0032 16.9 0.5 1.4 8.2 0.0 3.7 3 1 0 4 4 3 1 AAA domain TrwB_AAD_bind PF10412.4 KOS13435.1 - 0.0053 15.4 0.0 1.9 7.0 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF258 PF03193.11 KOS13435.1 - 0.0075 15.4 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 KOS13435.1 - 0.0085 15.7 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 KOS13435.1 - 0.021 13.7 0.0 0.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EMP24_GP25L PF01105.19 KOS13435.1 - 0.022 14.4 0.6 0.044 13.5 0.4 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SRP54 PF00448.17 KOS13435.1 - 0.041 13.3 0.0 12 5.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 KOS13435.1 - 0.048 13.2 0.0 13 5.4 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KOS13435.1 - 0.048 13.4 0.0 7.6 6.3 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 KOS13435.1 - 0.063 12.9 0.1 1.2 8.7 0.0 2.7 2 1 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 KOS13435.1 - 0.064 12.7 0.1 7.9 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KOS13435.1 - 0.15 11.4 7.0 11 5.2 0.0 4.2 3 2 0 5 5 4 0 AAA-like domain IncA PF04156.9 KOS13435.1 - 0.74 9.3 11.8 0.25 10.9 5.7 2.0 2 0 0 2 2 2 0 IncA protein AAA_23 PF13476.1 KOS13435.1 - 1.2 9.4 11.1 2.9 8.1 0.0 3.3 3 1 0 3 3 2 0 AAA domain PilJ PF13675.1 KOS13435.1 - 1.8 8.9 8.6 1.8 8.9 3.2 3.3 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_MLP1_2 PF07926.7 KOS13435.1 - 2.6 7.8 11.6 16 5.2 6.7 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KOS13435.1 - 5 5.4 13.2 0.37 9.1 5.3 1.8 3 0 0 3 3 3 0 AAA domain SWI-SNF_Ssr4 PF08549.5 KOS13436.1 - 0.0014 17.0 0.0 0.0014 17.0 0.0 2.2 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1750) TFIIA PF03153.8 KOS13436.1 - 8.6 6.1 8.2 12 5.7 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 KOS13437.1 - 8e-42 142.7 0.0 1.6e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KOS13437.1 - 1.1e-13 51.0 4.5 7.9e-13 48.3 3.0 2.4 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KOS13437.1 - 6.7e-06 26.0 0.0 0.00069 19.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KOS13437.1 - 4.9e-05 23.4 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS13437.1 - 0.0003 20.8 0.1 0.00076 19.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KOS13437.1 - 0.0024 18.3 0.0 0.11 13.0 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS13437.1 - 0.015 14.4 0.0 7.6 5.7 0.0 3.1 3 1 0 3 3 3 0 ADP-ribosylation factor family G-alpha PF00503.15 KOS13437.1 - 0.096 11.3 0.2 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Aminotran_5 PF00266.14 KOS13438.1 - 2e-35 122.2 0.0 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Actin PF00022.14 KOS13439.1 - 2.7e-55 187.4 0.0 3.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS13439.1 - 0.15 10.6 0.0 0.34 9.4 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein Coiled-coil_56 PF09813.4 KOS13439.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Cmc1 PF08583.5 KOS13440.1 - 1.5e-16 59.9 3.9 1.8e-16 59.6 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KOS13440.1 - 0.013 15.3 3.9 0.025 14.5 2.4 1.8 1 1 1 2 2 2 0 CHCH domain Taeniidae_ag PF05596.6 KOS13440.1 - 0.096 12.5 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Taeniidae antigen Pet191_N PF10203.4 KOS13440.1 - 1 9.4 4.4 14 5.8 2.5 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Anticodon_1 PF08264.8 KOS13441.1 - 0.0013 18.5 0.1 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Cohesin_HEAT PF12765.2 KOS13441.1 - 0.015 15.2 0.3 32 4.6 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KOS13441.1 - 0.065 13.3 15.9 32 4.9 0.1 7.6 8 0 0 8 8 8 0 HEAT repeat Ion_trans PF00520.26 KOS13442.1 - 9e-06 25.0 2.9 9e-06 25.0 2.0 1.7 2 0 0 2 2 2 1 Ion transport protein ACT_5 PF13710.1 KOS13442.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 ACT domain zf-RING_2 PF13639.1 KOS13443.1 - 5.3e-07 29.3 17.8 9.6e-07 28.5 12.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS13443.1 - 8.8e-07 28.4 13.0 1.5e-06 27.7 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS13443.1 - 3.8e-05 23.6 17.8 6.7e-05 22.8 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS13443.1 - 0.00018 21.0 17.0 0.00032 20.2 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS13443.1 - 0.0048 16.6 8.3 0.0096 15.7 5.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Papo_T_antigen PF02380.10 KOS13443.1 - 0.037 13.9 5.0 0.085 12.7 3.5 1.6 1 0 0 1 1 1 0 T-antigen specific domain DUF2785 PF10978.3 KOS13443.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) zf-rbx1 PF12678.2 KOS13443.1 - 0.13 12.4 15.8 0.45 10.6 11.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger DAO PF01266.19 KOS13444.1 - 6.2e-49 166.8 1.1 7.9e-49 166.4 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS13444.1 - 4.6e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS13444.1 - 0.00075 19.6 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS13444.1 - 0.0034 17.7 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KOS13444.1 - 0.019 13.1 0.0 0.035 12.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 KOS13444.1 - 0.031 13.2 0.0 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 KOS13444.1 - 0.031 14.2 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Aldedh PF00171.17 KOS13445.1 - 6.6e-79 265.4 0.0 7.8e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB_2 PF02214.17 KOS13445.1 - 0.017 15.3 0.1 0.067 13.4 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain SBDS PF01172.13 KOS13446.1 - 4.1e-16 58.5 0.0 4.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Not3 PF04065.10 KOS13447.1 - 1.3e-94 315.8 20.8 1.3e-94 315.8 14.4 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KOS13447.1 - 8.8e-44 148.6 9.2 8.8e-44 148.6 6.4 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 KOS13447.1 - 0.0039 16.6 2.1 0.0095 15.4 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Sec34 PF04136.10 KOS13447.1 - 0.14 11.8 3.8 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family Vps8 PF12816.2 KOS13448.1 - 1.8e-44 151.3 0.0 4.1e-44 150.1 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Glyco_tranf_2_3 PF13641.1 KOS13449.1 - 9e-21 74.7 0.0 1.3e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS13449.1 - 5.6e-20 71.8 4.2 1.1e-19 70.9 2.9 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KOS13449.1 - 4e-07 29.4 0.0 5.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS13449.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 NUC153 PF08159.7 KOS13450.1 - 2.4e-13 49.3 0.1 4.4e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KOS13451.1 - 2.1e-18 65.4 14.4 8.6e-09 34.9 2.6 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KOS13451.1 - 0.004 16.9 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KOS13451.1 - 0.08 11.6 0.1 1.5 7.5 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Iso_dh PF00180.15 KOS13452.1 - 6.3e-87 291.7 0.0 7.8e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Spo0A_C PF08769.6 KOS13452.1 - 0.1 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal RNA_pol_Rpb1_5 PF04998.12 KOS13453.1 - 6.8e-96 320.7 0.4 6.8e-96 320.7 0.3 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KOS13453.1 - 3.2e-91 306.1 0.0 3.2e-91 306.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KOS13453.1 - 1.4e-65 220.2 0.0 3.6e-65 218.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RRM_1 PF00076.17 KOS13453.1 - 4.6e-42 141.4 0.0 1.8e-21 75.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb1_3 PF04983.13 KOS13453.1 - 1.7e-38 131.8 0.0 4.2e-38 130.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RRM_6 PF14259.1 KOS13453.1 - 3.6e-31 106.9 0.0 3.1e-16 59.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb1_4 PF05000.12 KOS13453.1 - 2.5e-29 101.1 0.0 1.1e-28 99.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_5 PF13893.1 KOS13453.1 - 2.7e-21 75.1 0.0 1.8e-12 46.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 KOS13454.1 - 1.7e-57 193.7 0.0 2.8e-57 193.1 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS13454.1 - 2.8e-10 39.3 0.2 7.6e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.1 KOS13455.1 - 2e-49 168.2 38.3 2.4e-49 168.0 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS13455.1 - 3.3e-15 55.3 30.6 4.5e-15 54.9 21.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S7e PF01251.13 KOS13456.1 - 4.9e-76 254.4 0.3 5.4e-76 254.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e AA_permease_2 PF13520.1 KOS13457.1 - 2.1e-56 191.2 54.3 2.6e-56 190.9 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS13457.1 - 1.9e-36 125.4 48.0 2.5e-36 125.0 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KOS13458.1 - 7e-40 136.8 0.0 8.7e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13458.1 - 2.7e-17 62.6 0.0 3.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS13458.1 - 1.3e-05 25.0 0.9 0.0033 17.1 0.0 3.1 2 1 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KOS13458.1 - 0.032 13.0 0.1 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.20 KOS13459.1 - 1.3e-30 106.5 0.5 1.7e-30 106.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS13459.1 - 6.6e-28 98.0 0.1 9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS13459.1 - 4.3e-18 65.6 0.1 5.8e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KOS13459.1 - 6.8e-08 32.2 0.1 8.9e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KOS13459.1 - 0.00097 18.8 0.4 0.024 14.2 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KOS13459.1 - 0.0011 19.3 1.1 1.3 9.5 0.2 2.6 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KOS13459.1 - 0.0063 15.5 0.4 0.4 9.5 0.0 2.1 1 1 1 2 2 2 2 Saccharopine dehydrogenase Synaptonemal_3 PF15191.1 KOS13459.1 - 0.099 12.3 0.3 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Med4 PF10018.4 KOS13460.1 - 1.9e-23 82.8 3.1 3.1e-23 82.1 2.1 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TEX13 PF15186.1 KOS13460.1 - 0.0023 17.5 3.9 0.0031 17.0 2.7 1.2 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family HAUS-augmin3 PF14932.1 KOS13460.1 - 0.078 12.1 1.5 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF677 PF05055.7 KOS13460.1 - 0.095 11.3 0.2 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3818 PF12825.2 KOS13460.1 - 0.2 10.2 1.1 0.28 9.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) SNARE PF05739.14 KOS13461.1 - 4.5e-05 23.0 0.7 4.5e-05 23.0 0.5 3.1 3 0 0 3 3 3 1 SNARE domain Adenine_glyco PF03352.8 KOS13461.1 - 0.082 12.4 0.4 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase SUV3_C PF12513.3 KOS13461.1 - 0.34 10.3 2.8 0.47 9.9 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal V-SNARE_C PF12352.3 KOS13461.1 - 0.53 10.3 7.7 0.2 11.7 0.3 3.2 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Peptidase_C6 PF00851.13 KOS13461.1 - 3.6 6.0 7.7 1.5 7.3 3.6 1.5 1 1 0 1 1 1 0 Helper component proteinase Mpv17_PMP22 PF04117.7 KOS13462.1 - 9.6e-22 76.4 0.5 1.4e-21 75.8 0.4 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family Aminotran_3 PF00202.16 KOS13463.1 - 1.4e-42 145.7 0.0 6.5e-22 77.8 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KOS13463.1 - 6.1e-26 91.2 0.0 1.5e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Bac_surface_Ag PF01103.18 KOS13464.1 - 5.3e-36 124.7 0.0 6.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Surface antigen MutS_V PF00488.16 KOS13465.1 - 2.6e-92 308.4 0.0 4.5e-92 307.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS13465.1 - 1.3e-33 116.4 0.2 3e-33 115.3 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KOS13465.1 - 4.8e-18 65.5 0.1 1.2e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 KOS13465.1 - 7.3e-16 58.2 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KOS13465.1 - 1.5e-15 57.1 0.0 5.1e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV Ribosomal_L13e PF01294.13 KOS13466.1 - 1.1e-61 207.4 7.4 1.7e-61 206.8 5.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Gcd10p PF04189.8 KOS13467.1 - 1.1e-74 251.2 0.0 4.8e-74 249.1 0.0 1.8 1 1 0 1 1 1 1 Gcd10p family Tcp10_C PF07202.8 KOS13467.1 - 0.12 11.9 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus CS PF04969.11 KOS13468.1 - 3.9e-13 49.7 0.0 1.4e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 CS domain DUF2220 PF09983.4 KOS13468.1 - 0.21 10.7 1.6 0.24 10.5 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) PC_rep PF01851.17 KOS13469.1 - 1.4e-17 62.8 17.0 2.1e-05 24.4 0.0 9.0 10 0 0 10 10 10 6 Proteasome/cyclosome repeat AMMECR1 PF01871.12 KOS13470.1 - 5.7e-42 142.7 0.0 1e-41 141.9 0.0 1.4 1 1 0 1 1 1 1 AMMECR1 DUF1748 PF08520.5 KOS13471.1 - 3.8e-25 87.3 0.2 4.1e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) LIP PF03583.9 KOS13472.1 - 1.8e-37 129.1 0.0 2.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_2 PF02230.11 KOS13472.1 - 0.0014 18.1 0.0 0.0067 15.8 0.0 1.8 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KOS13472.1 - 0.0039 17.0 0.0 0.0053 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KOS13472.1 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KOS13472.1 - 0.021 14.0 0.1 0.048 12.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KOS13472.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.2 KOS13472.1 - 0.047 13.4 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2920 PF11144.3 KOS13472.1 - 0.073 12.0 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) RF-1 PF00472.15 KOS13473.1 - 4.5e-23 81.2 7.9 5.7e-22 77.6 5.5 2.0 1 1 0 1 1 1 1 RF-1 domain Pkinase PF00069.20 KOS13474.1 - 1.1e-62 211.5 0.0 6.5e-62 209.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13474.1 - 9.9e-43 146.0 0.0 1.7e-42 145.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KOS13474.1 - 6.2e-38 130.3 0.4 1.1e-37 129.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 KOS13474.1 - 0.00011 21.2 0.1 0.011 14.7 0.0 2.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KOS13474.1 - 0.0063 16.2 5.0 0.013 15.2 0.0 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family DGF-1_C PF11040.3 KOS13474.1 - 0.036 13.9 0.2 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Snf7 PF03357.16 KOS13475.1 - 1.1e-40 138.7 19.7 1.1e-40 138.7 13.7 1.9 1 1 1 2 2 2 1 Snf7 TraF_2 PF13729.1 KOS13475.1 - 0.032 13.0 6.8 0.023 13.4 0.6 2.0 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF3508 PF12018.3 KOS13475.1 - 0.11 11.4 0.1 0.11 11.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) DUF1269 PF06897.7 KOS13475.1 - 0.15 12.0 0.6 1 9.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) ERM PF00769.14 KOS13475.1 - 0.94 8.9 22.2 1.2e+02 2.0 15.4 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.4 KOS13475.1 - 1.4 7.8 11.3 1.7 7.5 7.4 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 KOS13475.1 - 1.6 7.9 11.5 0.32 10.2 1.3 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein DNA_RNApol_7kD PF03604.8 KOS13476.1 - 1.3e-16 59.7 6.8 1.6e-16 59.4 4.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 KOS13476.1 - 0.0065 16.4 0.7 0.0065 16.4 0.5 1.7 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 KOS13476.1 - 0.013 15.1 0.4 0.016 14.9 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family NinF PF05810.7 KOS13476.1 - 0.039 13.7 0.3 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 NinF protein Zn-ribbon_8 PF09723.5 KOS13476.1 - 0.059 13.3 2.5 0.15 12.0 1.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.2 KOS13476.1 - 0.061 13.1 1.1 0.1 12.3 0.7 1.5 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.13 KOS13476.1 - 0.12 11.9 1.2 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.6 KOS13476.1 - 0.18 11.4 1.0 0.25 11.0 0.7 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2197 PF09963.4 KOS13476.1 - 0.18 11.7 4.0 1.6 8.7 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zinc_ribbon_5 PF13719.1 KOS13476.1 - 0.31 10.6 2.4 2.2 7.9 1.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DUF2296 PF10058.4 KOS13476.1 - 0.32 10.7 2.7 1.1 9.0 0.1 2.1 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_ribbon_recom PF13408.1 KOS13476.1 - 0.45 10.8 3.6 0.54 10.5 1.0 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 KOS13476.1 - 0.54 10.0 3.6 1.4 8.7 2.4 1.6 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KOS13476.1 - 0.7 9.2 3.2 5.8 6.3 0.1 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 KOS13476.1 - 1 8.9 3.6 3.3 7.3 1.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-trcl PF13451.1 KOS13476.1 - 9.9 5.8 6.8 3.8 7.2 0.9 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain S4 PF01479.20 KOS13477.1 - 1.3e-12 46.9 0.0 2.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain SAPS PF04499.10 KOS13477.1 - 0.03 12.9 0.4 0.039 12.5 0.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein S4_2 PF13275.1 KOS13477.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 S4 domain Tim54 PF11711.3 KOS13477.1 - 0.1 11.1 2.9 0.15 10.6 2.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.6 KOS13477.1 - 0.17 11.0 0.9 0.26 10.4 0.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 KOS13477.1 - 0.32 8.6 2.9 0.44 8.1 2.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 KOS13477.1 - 2.1 6.3 7.9 3.1 5.8 5.5 1.1 1 0 0 1 1 1 0 Menin NPR3 PF03666.8 KOS13477.1 - 4.8 5.6 5.8 7.3 5.0 4.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3827 PF12877.2 KOS13477.1 - 6.5 4.7 8.3 8.9 4.2 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF775 PF05603.7 KOS13478.1 - 1e-42 146.0 0.0 1.2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GspL_C PF12693.2 KOS13478.1 - 0.0045 16.7 3.1 0.0073 16.0 2.1 1.3 1 0 0 1 1 1 1 GspL periplasmic domain DAD PF02109.11 KOS13479.1 - 1.4e-39 134.6 1.9 1.6e-39 134.4 1.3 1.0 1 0 0 1 1 1 1 DAD family MCM PF00493.18 KOS13480.1 - 8.1e-134 445.5 0.0 3.2e-132 440.3 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KOS13480.1 - 4.4e-25 88.5 0.2 1.4e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS13480.1 - 2.7e-07 29.9 0.1 2.1e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS13480.1 - 1.4e-06 28.1 0.0 4.8e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS13480.1 - 0.016 14.7 0.1 0.095 12.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KOS13480.1 - 0.036 14.4 0.8 0.13 12.6 0.3 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KOS13480.1 - 0.051 13.0 0.1 0.85 9.0 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Aminotran_1_2 PF00155.16 KOS13481.1 - 1.5e-74 251.1 0.0 1.5e-74 251.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KOS13481.1 - 4.9e-08 32.1 0.0 1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KOS13481.1 - 0.0002 19.7 0.0 0.00053 18.3 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KOS13481.1 - 0.073 12.1 0.1 0.18 10.8 0.0 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DHHA1 PF02272.14 KOS13481.1 - 0.088 12.5 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 DHHA1 domain BDV_P10 PF06515.6 KOS13481.1 - 1.8 8.4 4.9 9.2 6.1 0.2 3.1 3 0 0 3 3 3 0 Borna disease virus P10 protein Ribosomal_S3Ae PF01015.13 KOS13482.1 - 2.4e-82 275.0 4.2 2.8e-82 274.7 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 KOS13482.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Taeniidae_ag PF05596.6 KOS13482.1 - 0.041 13.6 0.2 2.4 8.0 0.0 2.9 1 1 1 2 2 2 0 Taeniidae antigen Peptidase_M76 PF09768.4 KOS13483.1 - 2.9e-66 222.1 0.1 3.6e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 KOS13483.1 - 0.015 15.5 1.6 0.95 9.7 0.2 2.3 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus SprT-like PF10263.4 KOS13483.1 - 0.021 14.4 4.3 0.047 13.3 3.0 1.7 1 1 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 KOS13483.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily RNA_pol_Rbc25 PF08292.7 KOS13484.1 - 6.4e-35 120.0 0.0 1.4e-34 118.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KOS13484.1 - 2.3e-19 69.2 0.1 1.2e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mpp10 PF04006.7 KOS13485.1 - 1.6e-89 300.9 110.1 1.7e-87 294.2 76.3 2.6 1 1 0 1 1 1 1 Mpp10 protein Ribosomal_S11 PF00411.14 KOS13486.1 - 3.1e-41 139.9 0.6 3.7e-41 139.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KOS13486.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 KOS13486.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) OPT PF03169.10 KOS13487.1 - 4.1e-173 577.1 56.9 4.7e-173 576.9 39.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EVE PF01878.13 KOS13488.1 - 3.6e-44 150.2 0.0 9.3e-44 148.9 0.0 1.6 1 1 0 1 1 1 1 EVE domain DUF1891 PF09004.5 KOS13488.1 - 0.089 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Ribosomal_S14 PF00253.16 KOS13489.1 - 3.6e-18 64.6 0.1 7.6e-18 63.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Peptidase_M28 PF04389.12 KOS13490.1 - 5.8e-19 68.5 0.1 1.2e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KOS13490.1 - 1.6e-14 53.5 0.1 2.9e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KOS13490.1 - 1.1e-07 31.4 0.1 9.1e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 PA domain Pkinase PF00069.20 KOS13491.1 - 1.1e-66 224.6 0.0 1.4e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13491.1 - 1.2e-38 132.6 0.0 1.8e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13491.1 - 1.1e-08 34.4 0.0 1.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS13491.1 - 0.0078 15.2 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sedlin_N PF04628.8 KOS13492.1 - 2.3e-22 79.2 0.0 3.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KOS13492.1 - 3.7e-06 26.7 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Inhibitor_I9 PF05922.11 KOS13492.1 - 0.00077 19.9 0.0 0.0022 18.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 HNF-1A_C PF04813.7 KOS13492.1 - 0.08 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus IMD PF08397.6 KOS13493.1 - 0.02 14.2 8.7 0.08 12.2 6.1 2.2 1 1 0 1 1 1 0 IRSp53/MIM homology domain TPR_MLP1_2 PF07926.7 KOS13493.1 - 0.055 13.2 11.2 0.032 13.9 4.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPR_11 PF13414.1 KOS13493.1 - 0.057 13.0 0.9 1.1 8.9 0.3 2.9 2 1 1 3 3 3 0 TPR repeat BBP1_C PF15272.1 KOS13493.1 - 0.39 10.2 9.2 0.043 13.3 3.2 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Wbp11 PF09429.5 KOS13493.1 - 1.8 8.5 7.0 1.7 8.6 3.8 1.7 1 1 0 1 1 1 0 WW domain binding protein 11 DUF1640 PF07798.6 KOS13494.1 - 2.8e-16 60.0 0.2 4e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.13 KOS13494.1 - 0.0056 16.2 2.6 0.01 15.3 1.8 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain OmpH PF03938.9 KOS13494.1 - 0.017 15.0 0.6 0.033 14.1 0.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cu_amine_oxidN1 PF07833.6 KOS13494.1 - 0.086 13.1 0.0 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain Corona_S2 PF01601.11 KOS13494.1 - 0.15 10.1 0.1 0.21 9.6 0.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein IncA PF04156.9 KOS13494.1 - 0.67 9.5 9.8 0.73 9.3 5.9 1.6 1 1 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 KOS13494.1 - 0.83 9.4 5.6 2.1 8.1 3.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 KOS13494.1 - 0.93 9.8 7.3 0.06 13.6 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KOS13494.1 - 1.8 6.9 10.6 0.4 9.0 1.8 2.0 2 0 0 2 2 2 0 AAA domain Flavin_Reduct PF01613.13 KOS13495.1 - 2e-27 95.9 0.3 2.7e-27 95.4 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain WLM PF08325.5 KOS13496.1 - 1.7e-27 96.4 0.0 2.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain WD40 PF00400.27 KOS13497.1 - 3.3e-22 77.4 1.5 1.1e-09 37.8 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KOS13497.1 - 0.043 13.3 0.0 4.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.11 KOS13498.1 - 1.7e-18 66.4 57.3 3e-15 55.8 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0240 PF06784.6 KOS13499.1 - 0.0045 16.6 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) HTH_Tnp_4 PF13613.1 KOS13499.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ING PF12998.2 KOS13500.1 - 3.2e-16 59.5 0.1 7.5e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PLDc_2 PF13091.1 KOS13500.1 - 1.4e-08 34.5 0.0 0.00021 21.0 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PHD PF00628.24 KOS13500.1 - 3.5e-08 32.9 9.4 1e-07 31.4 6.5 1.9 1 0 0 1 1 1 1 PHD-finger PLDc PF00614.17 KOS13500.1 - 1.5e-06 27.8 5.7 0.0018 18.0 0.2 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif zf-HC5HC2H PF13771.1 KOS13500.1 - 0.049 13.7 1.0 0.16 12.1 0.7 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Acyl-CoA_dh_M PF02770.14 KOS13500.1 - 0.14 11.6 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Toxin_trans PF07952.7 KOS13500.1 - 0.27 10.0 0.1 0.46 9.3 0.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Aa_trans PF01490.13 KOS13501.1 - 5.2e-56 189.8 17.5 6.6e-56 189.5 12.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KOS13501.1 - 0.00034 19.5 11.7 0.00034 19.5 8.1 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Ammonium_transp PF00909.16 KOS13502.1 - 0.57 8.6 2.0 0.84 8.0 1.4 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Amidase PF01425.16 KOS13503.1 - 1.3e-84 284.6 0.0 1.5e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 Amidase GD_AH_C PF04295.8 KOS13503.1 - 0.13 10.9 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 D-galactarate dehydratase / Altronate hydrolase, C terminus AAA PF00004.24 KOS13504.1 - 2.6e-41 140.8 0.0 5.1e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KOS13504.1 - 3.8e-05 23.6 0.1 0.00046 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KOS13504.1 - 0.00017 21.6 0.1 0.0078 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KOS13504.1 - 0.00024 20.2 0.0 0.00052 19.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS13504.1 - 0.00024 21.2 0.4 0.016 15.3 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS13504.1 - 0.00028 20.6 1.4 0.0016 18.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 KOS13504.1 - 0.00068 18.9 2.1 0.0078 15.4 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_17 PF13207.1 KOS13504.1 - 0.0032 18.2 0.1 0.0092 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS13504.1 - 0.0043 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS13504.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KOS13504.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KOS13504.1 - 0.012 14.8 0.1 0.04 13.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS13504.1 - 0.019 14.4 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 KOS13504.1 - 0.039 12.8 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KOS13504.1 - 0.048 13.0 1.5 0.33 10.3 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS13504.1 - 0.059 12.9 0.6 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain GrpE PF01025.14 KOS13504.1 - 0.067 12.7 1.6 0.1 12.1 0.3 1.9 2 0 0 2 2 2 0 GrpE RNA_helicase PF00910.17 KOS13504.1 - 0.1 12.7 0.0 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.1 KOS13504.1 - 0.11 12.1 0.2 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KOS13504.1 - 0.12 11.4 1.1 0.36 9.8 0.0 2.3 3 0 0 3 3 3 0 KaiC Ribosomal_S9 PF00380.14 KOS13505.1 - 3e-41 140.4 0.4 3.4e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 FUN14 PF04930.10 KOS13506.1 - 2.3e-20 72.7 0.1 3.6e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 FUN14 family Ycf66_N PF07444.6 KOS13506.1 - 0.056 13.1 0.3 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF2198 PF09964.4 KOS13506.1 - 0.14 11.9 0.4 0.3 10.8 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Pkinase PF00069.20 KOS13507.1 - 5.6e-71 238.7 0.0 8.9e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13507.1 - 2.2e-47 161.2 0.0 3.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KOS13507.1 - 3.1e-21 75.5 0.0 7.5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KOS13507.1 - 1.9e-06 27.0 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13507.1 - 0.0054 16.4 0.1 0.21 11.2 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DSHCT PF08148.7 KOS13507.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain BAR PF03114.13 KOS13508.1 - 2.1e-36 125.5 5.1 3.1e-36 125.0 3.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KOS13508.1 - 6.4e-16 57.4 0.0 1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS13508.1 - 6.2e-15 54.5 0.1 9.7e-15 53.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS13508.1 - 4.8e-12 45.1 0.0 7.7e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TcdB_N PF12918.2 KOS13508.1 - 0.036 14.1 1.5 0.036 14.1 1.0 2.5 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Myosin_tail_1 PF01576.14 KOS13508.1 - 0.046 11.4 4.3 0.066 10.9 1.8 1.8 2 0 0 2 2 2 0 Myosin tail ADIP PF11559.3 KOS13508.1 - 0.068 13.0 5.3 1.2 9.0 2.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 KOS13508.1 - 5.4 6.8 6.8 7.3 6.4 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper PRP38 PF03371.10 KOS13509.1 - 1.1e-62 210.6 0.1 1.6e-62 210.1 0.1 1.2 1 0 0 1 1 1 1 PRP38 family Kinesin PF00225.18 KOS13510.1 - 1.2e-91 306.9 0.0 1.6e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Med4 PF10018.4 KOS13510.1 - 0.25 10.7 3.2 0.38 10.1 1.5 1.7 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin-6_N PF09177.6 KOS13510.1 - 1.4 9.3 3.8 0.95 9.9 1.0 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlgN PF05130.7 KOS13510.1 - 2.5 8.3 16.2 0.1 12.8 4.3 2.8 2 1 1 3 3 3 0 FlgN protein Muted PF14942.1 KOS13510.1 - 2.7 7.8 5.8 6.4 6.6 0.8 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein PHF5 PF03660.9 KOS13511.1 - 7.6e-18 64.5 1.4 8.6e-18 64.3 1.0 1.1 1 0 0 1 1 1 1 PHF5-like protein Myosin_head PF00063.16 KOS13512.1 - 4.4e-241 801.7 0.0 6.5e-241 801.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 KOS13512.1 - 7.5e-36 122.1 2.4 2.2e-35 120.7 1.7 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KOS13512.1 - 2.4e-11 42.2 38.2 0.0031 17.0 1.5 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KOS13512.1 - 8.5e-05 22.7 0.0 0.00076 19.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain Seryl_tRNA_N PF02403.17 KOS13512.1 - 0.0025 17.7 5.3 0.0057 16.6 3.1 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 KOS13512.1 - 0.016 15.0 10.8 0.041 13.7 7.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KOS13512.1 - 0.045 13.6 1.0 9.9 6.1 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MAD PF05557.8 KOS13512.1 - 0.05 11.7 18.2 0.074 11.1 12.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Reo_sigmaC PF04582.7 KOS13512.1 - 0.076 12.1 2.1 0.13 11.3 1.4 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KOS13512.1 - 0.08 12.6 9.0 0.23 11.1 1.0 2.7 1 1 1 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.3 KOS13512.1 - 0.086 12.6 13.1 1.5 8.6 2.2 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KOS13512.1 - 0.12 11.9 13.9 0.052 13.0 2.3 3.7 2 1 0 3 3 3 0 Septum formation initiator DUF342 PF03961.8 KOS13512.1 - 0.15 10.3 3.3 0.27 9.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ABC_tran PF00005.22 KOS13512.1 - 0.16 12.2 0.7 0.85 9.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter IncA PF04156.9 KOS13512.1 - 0.17 11.4 14.1 0.4 10.2 9.8 1.6 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KOS13512.1 - 0.65 10.3 7.3 7.7 6.9 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 KOS13512.1 - 0.69 8.8 10.3 1.4 7.8 7.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 KOS13512.1 - 0.98 8.9 8.4 4.1 6.9 1.2 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 KOS13512.1 - 1 9.5 5.0 0.53 10.4 1.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KOS13512.1 - 1.9 6.8 6.0 6.3 5.1 4.2 1.6 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KOS13512.1 - 4.4 6.9 13.9 1.1e+02 2.4 7.1 3.8 3 1 0 3 3 3 0 Mnd1 family FGGY_C PF02782.11 KOS13513.1 - 7.7e-39 133.3 0.7 1.4e-38 132.5 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KOS13513.1 - 5.5e-20 71.7 1.1 4.5e-19 68.7 0.1 2.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KOS13513.1 - 0.0015 17.8 0.6 0.23 10.7 0.0 2.5 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 KOS13513.1 - 0.0036 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase UPF0075 PF03702.9 KOS13513.1 - 0.023 13.6 0.2 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) FtsA PF14450.1 KOS13513.1 - 0.063 13.1 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Cell division protein FtsA MFS_1 PF07690.11 KOS13514.1 - 2.3e-38 131.8 27.5 2.3e-38 131.8 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 KOS13514.1 - 6.4 6.0 10.1 0.69 9.1 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) Ras PF00071.17 KOS13515.1 - 3.2e-48 163.1 0.4 3.6e-48 162.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS13515.1 - 2.8e-15 56.8 0.1 4.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS13515.1 - 1.4e-07 30.9 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS13515.1 - 2.2e-06 27.6 0.0 3.5e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KOS13515.1 - 3.2e-05 23.4 0.1 0.00029 20.3 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KOS13515.1 - 0.00025 20.3 0.0 0.0085 15.3 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KOS13515.1 - 0.0077 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KOS13515.1 - 0.022 14.4 0.3 0.037 13.7 0.2 1.6 1 1 0 1 1 1 0 Archaeal ATPase Baculo_p74 PF04583.7 KOS13515.1 - 0.03 13.5 0.1 0.58 9.3 0.0 2.0 1 1 1 2 2 2 0 Baculoviridae p74 conserved region ADH_N PF08240.7 KOS13516.1 - 1.7e-28 98.5 0.2 3e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS13516.1 - 1.9e-16 59.7 0.3 3e-16 59.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS13516.1 - 8.1e-06 26.7 0.7 1.8e-05 25.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KOS13516.1 - 0.043 12.8 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KOS13516.1 - 0.056 13.3 0.1 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS13516.1 - 0.088 11.2 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein SNARE_assoc PF09335.6 KOS13517.1 - 1.9e-13 50.6 7.6 6.4e-13 48.9 5.2 2.0 1 0 0 1 1 1 1 SNARE associated Golgi protein MFS_1 PF07690.11 KOS13518.1 - 1e-33 116.5 40.8 1e-33 116.5 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KOS13518.1 - 8.7e-09 34.1 5.1 1.7e-08 33.1 3.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L19 PF01245.15 KOS13519.1 - 3.2e-24 84.8 0.0 5.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 JAB PF01398.16 KOS13520.1 - 2.2e-16 59.6 0.0 4.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KOS13520.1 - 2.6e-05 23.7 0.1 8.4e-05 22.0 0.1 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DSPc PF00782.15 KOS13521.1 - 4.3e-14 52.2 0.0 1.2e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PyrI_C PF02748.10 KOS13521.1 - 0.06 12.7 0.2 5.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TPR_1 PF00515.23 KOS13523.1 - 1.4e-28 97.3 8.9 6.6e-07 28.6 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KOS13523.1 - 6.8e-26 89.7 11.8 2.9e-11 42.8 0.3 5.6 4 1 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 KOS13523.1 - 3.5e-23 79.6 18.2 0.00016 21.3 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13523.1 - 1.1e-20 71.8 4.5 1.9e-05 24.1 0.1 7.4 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13523.1 - 5.4e-17 60.7 9.3 0.00033 21.0 0.1 8.1 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13523.1 - 2.7e-16 59.2 13.5 1.7e-05 24.6 0.0 6.0 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13523.1 - 3.4e-16 59.4 12.9 3e-06 27.7 0.1 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KOS13523.1 - 1.7e-12 46.4 9.6 0.00047 20.1 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13523.1 - 2.6e-12 45.5 11.5 0.064 13.0 0.1 7.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13523.1 - 2.2e-08 34.2 3.6 0.014 15.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13523.1 - 2.9e-08 33.6 6.9 3.9 8.1 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.5 KOS13523.1 - 2.2e-06 26.7 0.4 1.5e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 KOS13523.1 - 3e-06 26.9 15.3 0.0097 15.7 0.3 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 KOS13523.1 - 5.4e-06 25.6 10.9 0.0052 15.8 0.1 4.8 1 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS13523.1 - 6.8e-05 22.9 9.1 0.079 13.0 0.1 4.0 2 1 2 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KOS13523.1 - 0.012 15.3 5.0 0.8 9.5 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KOS13523.1 - 0.16 11.8 2.3 0.74 9.7 0.1 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain RabGAP-TBC PF00566.13 KOS13524.1 - 1.8e-23 83.1 0.0 2.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ARID PF01388.16 KOS13526.1 - 0.0019 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HhH-GPD PF00730.20 KOS13528.1 - 1.8e-16 60.3 0.0 2.9e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KOS13528.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 KOS13528.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain RhoGAP PF00620.22 KOS13529.1 - 3e-35 121.0 0.0 5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DCX PF03607.12 KOS13530.1 - 0.067 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Doublecortin GAS2 PF02187.12 KOS13530.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain SWIB PF02201.13 KOS13531.1 - 3.6e-14 52.1 0.0 7.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Ras PF00071.17 KOS13532.1 - 5.3e-58 194.9 0.0 6.7e-58 194.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS13532.1 - 3.2e-20 72.8 0.0 6.2e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS13532.1 - 9.3e-17 60.8 0.0 3.1e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS13532.1 - 5.2e-09 35.5 0.0 6.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS13532.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS13532.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS13532.1 - 0.0018 18.2 0.1 0.0036 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KOS13532.1 - 0.0088 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KOS13532.1 - 0.024 13.8 0.1 0.12 11.5 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KOS13532.1 - 0.053 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 KOS13532.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain PP_M1 PF03012.9 KOS13532.1 - 0.079 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoprotein AAA_14 PF13173.1 KOS13532.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Utp11 PF03998.8 KOS13533.1 - 2.2e-55 188.1 25.1 2.9e-55 187.7 17.4 1.1 1 0 0 1 1 1 1 Utp11 protein CP12 PF02672.10 KOS13533.1 - 5.4 7.5 8.0 0.3 11.5 1.0 2.3 3 0 0 3 3 3 0 CP12 domain Dynein_light PF01221.13 KOS13534.1 - 3e-36 123.2 0.0 3.6e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 MAAL_C PF07476.6 KOS13534.1 - 0.0045 15.9 0.0 0.0052 15.7 0.0 1.0 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Imm28 PF15574.1 KOS13534.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Immunity protein 28 UQ_con PF00179.21 KOS13535.1 - 1.4e-45 154.1 0.0 1.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS13535.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KOS13535.1 - 0.081 12.8 1.5 0.11 12.4 1.1 1.4 1 1 0 1 1 1 0 RWD domain NUFIP1 PF10453.4 KOS13536.1 - 3.4e-14 52.0 0.6 7e-14 51.0 0.4 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF572 PF04502.8 KOS13536.1 - 0.59 9.2 7.6 1 8.5 5.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LRR_8 PF13855.1 KOS13537.1 - 3.3e-23 81.1 44.3 3.4e-09 36.3 5.0 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 KOS13537.1 - 3.4e-20 71.2 18.4 4.6e-07 29.3 1.8 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS13537.1 - 5.9e-13 46.9 14.5 0.64 10.2 0.0 8.4 7 1 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 KOS13537.1 - 1.1e-11 42.8 19.5 0.065 13.4 0.1 7.9 7 0 0 7 7 7 4 Leucine rich repeat zf-CCCH PF00642.19 KOS13537.1 - 1.5e-05 24.5 6.2 0.00059 19.4 0.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_6 PF13516.1 KOS13537.1 - 5.6e-05 22.8 17.7 0.11 12.6 0.1 7.1 7 0 0 7 7 7 3 Leucine Rich repeat zf-CCCH_2 PF14608.1 KOS13537.1 - 5.3 7.1 12.5 0.55 10.3 3.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 KOS13538.1 - 9.7e-64 215.0 0.0 4.4e-63 212.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13538.1 - 4.3e-22 78.4 0.1 2.4e-19 69.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS13538.1 - 0.002 17.1 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KOS13539.1 - 2.6e-56 190.6 0.0 3.5e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13539.1 - 4.1e-19 68.6 0.1 7.2e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS13539.1 - 0.00042 20.1 0.0 0.0022 17.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KOS13539.1 - 0.0024 17.2 0.2 0.0049 16.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KOS13539.1 - 0.03 13.3 0.4 0.053 12.5 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KOS13539.1 - 0.047 13.2 0.3 0.099 12.1 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 KOS13539.1 - 0.093 11.5 0.3 0.22 10.2 0.2 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KOS13540.1 - 8.6e-67 225.0 0.0 1.3e-66 224.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13540.1 - 3.8e-28 98.2 0.0 1.1e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS13540.1 - 3.3e-08 32.8 0.0 0.015 14.2 0.0 3.0 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 KOS13540.1 - 0.051 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_Me_trans PF04252.8 KOS13541.1 - 2e-24 86.0 0.0 7.6e-19 67.8 0.0 3.1 2 1 0 2 2 2 2 Predicted SAM-dependent RNA methyltransferase Rho_GDI PF02115.12 KOS13542.1 - 1.4e-47 161.7 0.0 1.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor zf-Tim10_DDP PF02953.10 KOS13543.1 - 1.4e-19 69.0 3.3 2e-19 68.6 2.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1178 PF06676.6 KOS13543.1 - 0.038 14.2 0.2 0.044 13.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Phasin_2 PF09361.5 KOS13543.1 - 0.043 13.8 0.2 0.081 12.9 0.1 1.5 1 1 0 1 1 1 0 Phasin protein Mmp37 PF09139.6 KOS13543.1 - 0.057 12.4 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 RRM_1 PF00076.17 KOS13544.1 - 4.8e-26 90.1 0.0 2.5e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13544.1 - 2.7e-15 56.0 0.0 1e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13544.1 - 3e-10 39.7 0.0 5.5e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS13544.1 - 0.00079 19.1 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 KOS13544.1 - 0.0014 18.1 1.5 0.0033 16.8 1.1 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain RRM_3 PF08777.6 KOS13544.1 - 0.064 13.1 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF2360 PF10152.4 KOS13544.1 - 0.15 12.3 7.7 0.25 11.6 5.3 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) EF-hand_7 PF13499.1 KOS13545.1 - 3.4e-16 59.1 0.0 3.2e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS13545.1 - 1.9e-14 52.1 0.4 4.2e-05 23.0 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KOS13545.1 - 1.1e-12 46.2 3.1 5.8e-05 22.1 0.0 3.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 KOS13545.1 - 2.7e-09 36.4 0.1 0.00069 19.1 0.0 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 KOS13545.1 - 1.9e-08 34.1 0.0 0.0015 18.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KOS13545.1 - 2.9e-07 29.5 0.2 0.017 14.4 0.0 3.1 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 KOS13545.1 - 0.017 14.7 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 KOS13545.1 - 0.046 13.7 0.0 1.1 9.3 0.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Sod_Fe_C PF02777.13 KOS13546.1 - 3.7e-16 58.8 0.0 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KOS13546.1 - 0.022 15.0 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Sec7 PF01369.15 KOS13547.1 - 1.2e-64 217.4 0.8 2.2e-64 216.6 0.1 1.8 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KOS13547.1 - 8.3e-54 181.5 4.1 8.3e-54 181.5 2.9 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KOS13547.1 - 1.1e-28 98.5 7.1 1.2e-26 92.0 0.0 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) Ytp1 PF10355.4 KOS13548.1 - 9e-93 310.3 4.6 1.3e-92 309.8 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KOS13548.1 - 9.1e-08 31.6 1.1 9.1e-08 31.6 0.7 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF1129 PF06570.6 KOS13548.1 - 5.3 6.2 7.6 22 4.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Complex1_LYR PF05347.10 KOS13549.1 - 2.1e-10 40.2 2.5 3.1e-10 39.6 1.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS13549.1 - 1.3e-07 31.7 2.0 2.1e-07 31.0 1.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like AA_permease PF00324.16 KOS13550.1 - 7.7e-129 430.1 35.8 8.8e-129 429.9 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS13550.1 - 3.6e-42 144.3 37.6 4.9e-42 143.9 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease ResIII PF04851.10 KOS13551.1 - 1.1e-19 70.9 0.0 2.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS13551.1 - 2e-18 66.4 0.0 7.5e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13551.1 - 1.4e-17 63.2 0.2 3e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lactamase_B_2 PF12706.2 KOS13552.1 - 2.3e-30 105.6 0.6 1.4e-28 99.7 0.5 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KOS13552.1 - 2.1e-13 49.5 0.0 5.9e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KOS13552.1 - 2.5e-09 37.0 0.6 1.9e-08 34.1 0.2 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Kinesin PF00225.18 KOS13553.1 - 1.6e-103 345.9 0.0 2.5e-103 345.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain UreD PF01774.12 KOS13553.1 - 0.0073 15.8 0.3 0.017 14.5 0.2 1.6 1 0 0 1 1 1 1 UreD urease accessory protein DUF4611 PF15387.1 KOS13553.1 - 0.042 13.9 0.3 0.042 13.9 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) IncA PF04156.9 KOS13553.1 - 0.41 10.2 19.4 0.59 9.7 2.1 3.5 3 0 0 3 3 3 0 IncA protein DivIC PF04977.10 KOS13553.1 - 6 6.4 20.0 5.6 6.5 0.0 5.0 4 1 1 5 5 5 0 Septum formation initiator VSG_B PF13206.1 KOS13553.1 - 7.6 5.5 17.5 0.039 13.0 0.4 3.2 4 0 0 4 4 4 0 Trypanosomal VSG domain Sec63 PF02889.11 KOS13554.1 - 1.4e-176 586.2 0.0 6.1e-91 304.9 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KOS13554.1 - 3.6e-47 159.9 0.2 3.5e-28 98.2 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KOS13554.1 - 1.4e-15 57.6 0.1 1.1e-09 38.3 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KOS13554.1 - 2.7e-11 43.1 0.0 2.1e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KOS13554.1 - 4.9e-07 29.9 0.0 0.032 14.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS13554.1 - 3.4e-05 23.5 0.2 0.014 15.1 0.1 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KOS13554.1 - 0.043 14.0 0.3 10 6.3 0.3 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KOS13555.1 - 2.7e-20 72.1 0.0 9.3e-20 70.4 0.0 2.0 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KOS13555.1 - 2.7e-13 49.8 0.0 4.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KOS13555.1 - 8e-06 26.0 0.5 2.2e-05 24.6 0.4 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS13555.1 - 8.3e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS13555.1 - 0.0014 18.6 0.8 0.012 15.5 0.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KOS13555.1 - 0.0014 17.4 0.0 0.0063 15.2 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KOS13555.1 - 0.0052 17.1 0.0 0.0075 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KOS13555.1 - 0.006 16.6 0.2 3.8 7.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 KOS13555.1 - 0.0088 15.7 0.4 0.3 10.7 0.3 2.4 1 1 0 1 1 1 1 Bacterial dnaA protein RuvB_N PF05496.7 KOS13555.1 - 0.021 13.8 1.1 0.23 10.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KOS13555.1 - 0.041 13.6 2.6 0.13 11.9 0.8 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KOS13555.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KOS13555.1 - 0.063 12.9 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KOS13555.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KOS13555.1 - 0.098 12.0 0.3 0.45 9.8 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain TRAM_LAG1_CLN8 PF03798.11 KOS13556.1 - 1.7e-32 112.5 33.0 1.7e-32 112.5 22.9 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KOS13556.1 - 1.8e-16 59.4 0.4 3.8e-14 51.9 0.1 3.1 2 1 0 2 2 2 2 TRAM1-like protein COX2-transmemb PF09125.5 KOS13556.1 - 1.3 8.6 7.8 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane DEAD PF00270.24 KOS13557.1 - 1.2e-37 128.9 0.0 2.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13557.1 - 3.4e-21 74.9 0.0 8.2e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS13557.1 - 2.5e-10 40.5 0.0 4.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS13557.1 - 0.013 15.5 0.6 0.096 12.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KOS13557.1 - 0.018 14.8 1.0 0.059 13.1 0.2 2.3 2 0 0 2 2 2 0 Part of AAA domain AMP-binding PF00501.23 KOS13558.1 - 2.1e-85 286.6 0.0 2.7e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS13558.1 - 0.025 15.4 0.0 0.11 13.4 0.0 2.2 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain hemP PF10636.4 KOS13558.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP Pro_isomerase PF00160.16 KOS13559.1 - 1.9e-48 164.6 0.3 2.2e-48 164.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KOS13560.1 - 2.2e-62 204.8 12.1 2.5e-10 39.8 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS13560.1 - 2e-10 40.7 0.4 0.00045 19.9 0.0 3.6 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KOS13560.1 - 0.0053 16.2 0.0 0.27 10.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain GATase PF00117.23 KOS13560.1 - 0.013 14.9 0.1 6.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase class-I CLU PF13236.1 KOS13561.1 - 4.4e-72 242.0 0.0 7e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KOS13561.1 - 1.5e-45 155.1 0.0 6e-45 153.2 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KOS13561.1 - 2.5e-18 65.7 2.2 5e-08 32.7 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KOS13561.1 - 2.5e-12 46.2 0.8 4e-05 23.3 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 KOS13561.1 - 4.5e-08 33.1 0.0 9.2e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF727 PF05303.7 KOS13561.1 - 0.0051 16.5 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF727) Sigma70_ner PF04546.8 KOS13561.1 - 0.044 13.4 3.0 0.034 13.7 0.7 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Arrestin_N PF00339.24 KOS13562.1 - 9.8e-07 28.7 0.0 3.1e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pet191_N PF10203.4 KOS13564.1 - 8.5e-24 83.3 2.5 9.9e-24 83.1 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KOS13564.1 - 1.3 8.8 4.9 18 5.1 0.1 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DnaJ PF00226.26 KOS13565.1 - 7.6e-23 80.0 0.1 1.2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Symplekin_C PF12295.3 KOS13566.1 - 5.8e-54 182.7 0.0 1.3e-53 181.6 0.0 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 KOS13566.1 - 4e-38 131.1 0.0 7.8e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Ribosomal_L10 PF00466.15 KOS13567.1 - 1.1e-24 86.2 0.2 3.8e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KOS13567.1 - 1.3e-21 76.7 9.4 1.3e-21 76.7 6.5 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1021 PF06257.6 KOS13567.1 - 0.043 13.5 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) Bud13 PF09736.4 KOS13568.1 - 6.2e-38 130.3 9.9 6.2e-38 130.3 6.9 2.9 1 1 1 2 2 2 1 Pre-mRNA-splicing factor of RES complex TFIIA PF03153.8 KOS13568.1 - 0.043 13.7 10.1 0.05 13.5 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 KOS13568.1 - 0.14 11.4 30.5 0.017 14.4 17.7 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF192 PF02643.10 KOS13568.1 - 0.32 10.7 3.3 1.6 8.4 0.1 2.8 1 1 1 2 2 2 0 Uncharacterized ACR, COG1430 DUF2962 PF11176.3 KOS13569.1 - 8e-39 132.6 1.2 9.5e-39 132.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Tetraspannin PF00335.15 KOS13570.1 - 0.0053 16.0 5.6 0.016 14.4 3.9 1.9 1 1 0 1 1 1 1 Tetraspanin family Shisa PF13908.1 KOS13570.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.1 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF4131 PF13567.1 KOS13570.1 - 6.3 6.1 6.8 1.8 7.9 2.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Cupin_8 PF13621.1 KOS13571.1 - 2.1e-14 53.6 0.0 9.2e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS13571.1 - 3.3e-10 40.2 0.0 9e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KOS13571.1 - 0.0055 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.2 KOS13571.1 - 0.021 14.5 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like Elongin_A PF06881.6 KOS13571.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MFS_1 PF07690.11 KOS13572.1 - 6.8e-16 57.9 49.2 1.8e-11 43.3 21.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily AAA PF00004.24 KOS13573.1 - 7.5e-14 52.0 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KOS13573.1 - 4.4e-06 25.6 0.0 0.008 14.9 0.0 2.8 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KOS13573.1 - 1.1e-05 24.6 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KOS13573.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KOS13573.1 - 0.00022 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KOS13573.1 - 0.00029 20.7 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KOS13573.1 - 0.00041 21.1 0.0 0.00092 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS13573.1 - 0.00041 19.4 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KOS13573.1 - 0.00067 19.3 0.0 0.00067 19.3 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 KOS13573.1 - 0.00077 19.6 0.0 0.0037 17.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KOS13573.1 - 0.00086 19.3 0.5 0.062 13.2 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KOS13573.1 - 0.0045 16.4 0.6 0.6 9.4 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KOS13573.1 - 0.012 15.4 0.0 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KOS13573.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KOS13573.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS13573.1 - 0.098 12.6 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KOS13573.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 KOS13573.1 - 0.27 10.9 0.1 0.84 9.3 0.0 1.7 1 1 1 2 2 2 0 NTPase Pkinase PF00069.20 KOS13574.1 - 3.8e-12 45.9 0.0 6.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KOS13574.1 - 3.5e-05 23.6 0.3 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS13574.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KOS13574.1 - 0.009 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS13574.1 - 0.015 14.3 0.1 0.059 12.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS13574.1 - 0.028 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Sterol-sensing PF12349.3 KOS13575.1 - 4e-36 123.7 9.6 6.9e-36 123.0 6.6 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KOS13575.1 - 9.8e-14 50.2 7.6 1.5e-13 49.6 5.2 1.1 1 0 0 1 1 1 1 Patched family DUF3357 PF11837.3 KOS13575.1 - 0.063 13.1 0.1 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) RhoGAP PF00620.22 KOS13576.1 - 1.1e-31 109.4 0.0 2.2e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KOS13576.1 - 5.4e-29 100.0 32.3 9e-14 51.2 3.2 4.6 4 0 0 4 4 4 4 LIM domain FA_hydroxylase PF04116.8 KOS13577.1 - 2.2e-15 57.0 9.5 3.7e-15 56.3 6.6 1.4 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily UCR_UQCRX_QCR9 PF05365.7 KOS13578.1 - 1e-25 89.0 1.4 1.2e-25 88.9 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.1 KOS13578.1 - 0.0023 17.7 0.6 0.0032 17.3 0.4 1.2 1 0 0 1 1 1 1 Tricorn protease C1 domain START PF01852.14 KOS13579.1 - 5.4e-22 78.1 3.1 1.9e-07 30.5 0.5 3.5 3 0 0 3 3 3 3 START domain Glyco_hydro_8 PF01270.12 KOS13581.1 - 2.7e-41 141.4 0.0 3.5e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 INO80_Ies4 PF08193.6 KOS13582.1 - 0.0028 17.6 0.4 0.0028 17.6 0.3 3.7 2 1 1 3 3 3 1 INO80 complex subunit Ies4 UBX PF00789.15 KOS13583.1 - 2e-11 43.7 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain THOC7 PF05615.8 KOS13585.1 - 3.9e-14 53.0 15.3 4.9e-14 52.7 9.6 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 AAA_13 PF13166.1 KOS13585.1 - 0.00045 18.8 9.0 0.00066 18.2 6.2 1.2 1 0 0 1 1 1 1 AAA domain MscS_porin PF12795.2 KOS13585.1 - 0.0046 16.2 17.3 0.24 10.6 6.9 2.5 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain DUF4559 PF15112.1 KOS13585.1 - 0.022 13.9 7.2 0.028 13.5 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Aminotran_4 PF01063.14 KOS13585.1 - 0.031 13.7 0.2 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Aminotransferase class IV CENP-F_leu_zip PF10473.4 KOS13585.1 - 0.049 13.4 12.3 0.21 11.4 5.7 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KOS13585.1 - 0.05 13.3 7.0 0.54 10.0 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain II Mnd1 PF03962.10 KOS13585.1 - 0.066 12.8 13.3 0.017 14.8 6.3 1.9 1 1 1 2 2 2 0 Mnd1 family Prefoldin_2 PF01920.15 KOS13585.1 - 0.1 12.3 12.0 3 7.6 4.4 3.0 2 1 0 3 3 3 0 Prefoldin subunit DIT1_PvcA PF05141.7 KOS13585.1 - 0.1 11.8 2.7 0.14 11.4 1.9 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Biopterin_H PF00351.16 KOS13585.1 - 0.23 10.1 2.2 0.45 9.2 1.3 1.5 1 1 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase FliJ PF02050.11 KOS13585.1 - 0.35 10.9 13.7 0.44 10.6 5.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Complex1_LYR_2 PF13233.1 KOS13585.1 - 0.59 10.6 5.2 1.3 9.5 3.3 1.9 1 1 0 1 1 1 0 Complex1_LYR-like NPV_P10 PF05531.7 KOS13585.1 - 0.71 10.1 4.0 4.5 7.5 0.1 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Hydrolase_3 PF08282.7 KOS13585.1 - 0.72 9.3 6.8 2 7.9 3.3 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase TBPIP PF07106.8 KOS13585.1 - 0.98 8.9 15.5 1.5 8.3 2.7 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Hemerythrin PF01814.18 KOS13585.1 - 1.1 9.4 6.0 11 6.2 2.7 2.5 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Seryl_tRNA_N PF02403.17 KOS13585.1 - 1.6 8.7 13.0 2.8 7.9 3.2 2.9 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain EAP30 PF04157.11 KOS13585.1 - 1.9 7.6 9.4 2.7 7.1 2.2 2.8 2 1 1 3 3 3 0 EAP30/Vps36 family YjcZ PF13990.1 KOS13585.1 - 2.2 7.3 9.3 3.1 6.8 3.8 2.1 1 1 0 2 2 2 0 YjcZ-like protein DUF342 PF03961.8 KOS13585.1 - 2.7 6.2 14.7 0.51 8.6 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 KOS13585.1 - 3 8.3 12.0 26 5.3 1.7 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal AAA_23 PF13476.1 KOS13585.1 - 3.3 7.9 8.2 5.4 7.2 5.6 1.4 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 KOS13585.1 - 5.3 7.8 10.5 5 7.9 5.6 2.2 1 1 1 2 2 2 0 Occludin homology domain MSA-2c PF12238.3 KOS13585.1 - 9.3 5.8 19.5 0.34 10.5 0.9 2.7 2 1 0 2 2 2 0 Merozoite surface antigen 2c SNARE PF05739.14 KOS13588.1 - 9.8e-14 50.7 5.8 9.8e-14 50.7 4.0 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KOS13588.1 - 9.1e-08 32.2 2.7 9.1e-08 32.2 1.8 2.4 2 0 0 2 2 2 1 Syntaxin PBP1_TM PF14812.1 KOS13588.1 - 0.00014 22.1 0.1 0.00033 20.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4658 PF15555.1 KOS13588.1 - 0.0075 16.1 0.5 4.3 7.2 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4658) DUF2077 PF09850.4 KOS13588.1 - 0.015 14.7 0.3 0.015 14.7 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF669 PF05037.8 KOS13588.1 - 0.054 13.3 1.5 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF669) DUF3611 PF12263.3 KOS13588.1 - 0.057 12.8 0.5 0.094 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Herpes_US9 PF06072.6 KOS13588.1 - 0.65 9.8 3.2 1.5 8.6 2.2 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Synaptobrevin PF00957.16 KOS13588.1 - 1.2 8.7 11.4 0.04 13.5 2.0 2.4 2 1 0 2 2 2 0 Synaptobrevin L1R_F9L PF02442.12 KOS13588.1 - 1.3 8.4 9.3 2.7 7.4 0.5 2.3 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DUF4094 PF13334.1 KOS13588.1 - 2.6 8.4 7.7 0.38 11.1 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) 7tm_7 PF08395.7 KOS13588.1 - 3.8 6.4 5.3 7.6 5.4 1.4 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor NPV_P10 PF05531.7 KOS13588.1 - 4.9 7.4 7.3 14 6.0 0.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cu-oxidase_2 PF07731.9 KOS13589.1 - 1.9e-40 137.5 1.4 2.6e-38 130.6 0.5 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KOS13589.1 - 1.8e-35 122.2 0.6 1.1e-33 116.4 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KOS13589.1 - 9.4e-26 89.8 4.4 3.5e-21 75.1 0.5 4.7 4 1 1 5 5 5 2 Multicopper oxidase RyR PF02026.11 KOS13589.1 - 0.0037 17.2 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 RyR domain Cupredoxin_1 PF13473.1 KOS13589.1 - 0.12 12.2 0.0 4.3 7.2 0.0 2.8 3 0 0 3 3 3 0 Cupredoxin-like domain ORC5_C PF14630.1 KOS13590.1 - 7.9e-43 146.8 0.1 1.3e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 KOS13590.1 - 0.012 15.7 0.0 0.058 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 KOS13591.1 - 2.2e-08 33.6 0.3 8.8e-06 25.4 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat RNB PF00773.14 KOS13592.1 - 2.4e-23 82.9 0.1 6e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 RNB domain Pyr_redox_3 PF13738.1 KOS13593.1 - 1.2e-19 71.2 0.0 9.1e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KOS13593.1 - 6.6e-19 68.0 0.0 5.5e-16 58.4 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS13593.1 - 2.5e-12 46.8 0.2 2.2e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS13593.1 - 3.2e-07 30.4 0.0 0.00061 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS13593.1 - 5.1e-05 22.2 0.2 0.00064 18.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KOS13593.1 - 9.9e-05 22.2 0.9 0.00055 19.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS13593.1 - 0.00012 21.0 1.8 0.00095 18.1 0.1 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KOS13593.1 - 0.00017 20.2 2.5 0.098 11.1 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 KOS13593.1 - 0.00033 20.9 0.1 1.8 9.0 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KOS13593.1 - 0.00045 20.3 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KOS13593.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FMO-like PF00743.14 KOS13593.1 - 0.0092 14.2 0.1 0.9 7.6 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 KOS13593.1 - 0.016 15.4 0.0 0.53 10.5 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KOS13593.1 - 0.017 14.2 0.1 0.05 12.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KOS13593.1 - 0.027 13.3 0.2 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KOS13593.1 - 0.058 12.4 0.1 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FrhB_FdhB_N PF04422.8 KOS13593.1 - 0.073 12.9 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TrkA_N PF02254.13 KOS13593.1 - 0.099 12.6 0.0 0.4 10.7 0.1 2.0 2 0 0 2 2 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KOS13593.1 - 0.18 10.9 0.0 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KOS13593.1 - 1.8 8.3 3.9 0.86 9.4 0.8 1.8 2 0 0 2 2 1 0 ThiF family Ada3 PF10198.4 KOS13594.1 - 4.1e-23 81.5 0.3 8.4e-23 80.5 0.2 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DASH_Spc34 PF08657.5 KOS13595.1 - 1.5e-15 57.5 6.9 6e-07 29.3 2.6 2.4 1 1 1 2 2 2 2 DASH complex subunit Spc34 Hexapep PF00132.19 KOS13596.1 - 2.6e-14 51.9 12.1 1.6e-08 33.6 1.4 4.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 KOS13596.1 - 4.7e-14 52.1 0.6 4.7e-14 52.1 0.4 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.7 KOS13596.1 - 0.00051 18.7 0.0 0.00079 18.0 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.1 KOS13596.1 - 0.0035 16.8 10.2 0.52 9.9 5.1 3.9 2 2 2 4 4 4 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KOS13596.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF3835 PF12927.2 KOS13597.1 - 0.18 12.7 0.0 0.18 12.7 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3835) DUF218 PF02698.12 KOS13598.1 - 1.2e-21 76.8 0.0 2.1e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain DAO PF01266.19 KOS13599.1 - 1.4e-19 70.2 0.1 2.9e-10 39.6 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS13599.1 - 2.9e-06 27.2 0.1 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS13599.1 - 6.4e-05 21.9 0.0 9.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KOS13599.1 - 7e-05 23.1 0.4 0.00018 21.8 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS13599.1 - 0.00027 20.8 0.3 0.00065 19.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KOS13599.1 - 0.0025 18.0 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KOS13599.1 - 0.0035 16.4 0.1 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS13599.1 - 0.0036 16.4 0.5 0.0086 15.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KOS13599.1 - 0.016 15.2 0.0 0.67 10.0 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KOS13599.1 - 0.021 13.7 0.1 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KOS13599.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KOS13599.1 - 0.04 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 KOS13599.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 KOS13599.1 - 0.18 10.2 0.1 0.26 9.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AKAP95 PF04988.7 KOS13600.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) RMP PF14996.1 KOS13600.1 - 0.079 12.8 0.3 0.25 11.2 0.2 1.8 1 1 0 1 1 1 0 Retinal Maintenance DNA_pol_A_exo1 PF01612.15 KOS13601.1 - 4e-19 68.7 0.0 6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 KOS13601.1 - 0.004 17.3 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain F-box-like PF12937.2 KOS13602.1 - 1.3e-06 27.9 2.4 1.8e-06 27.5 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KOS13602.1 - 0.00051 19.6 3.6 0.3 10.7 0.1 3.2 3 0 0 3 3 3 2 F-box domain AAA_13 PF13166.1 KOS13603.1 - 5.3e-07 28.5 44.4 0.00021 19.9 5.8 4.1 2 1 2 4 4 4 4 AAA domain DUF724 PF05266.9 KOS13603.1 - 0.00029 20.5 6.5 0.00029 20.5 4.5 6.5 3 2 3 7 7 7 1 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 KOS13603.1 - 0.0075 16.0 4.0 0.0075 16.0 2.8 10.0 8 3 2 11 11 11 3 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KOS13603.1 - 0.036 14.1 46.8 0.071 13.2 0.8 7.0 2 2 5 7 7 7 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KOS13603.1 - 0.52 10.1 4.9 8.6 6.3 0.2 4.4 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Linker_histone PF00538.14 KOS13604.1 - 0.00097 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family DEAD PF00270.24 KOS13605.1 - 1.5e-20 73.3 0.0 4.6e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13605.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rad21_Rec8_N PF04825.8 KOS13606.1 - 4.1e-33 113.6 0.0 7.2e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KOS13606.1 - 1.8e-12 46.2 0.0 3.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KOS13606.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 ScpA/B protein MFS_1 PF07690.11 KOS13607.1 - 5.1e-49 166.8 30.1 5.1e-49 166.8 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS13607.1 - 2.9e-16 59.1 2.7 2.9e-16 59.1 1.9 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 KOS13607.1 - 0.0034 15.4 6.2 0.0045 15.1 0.8 2.8 2 1 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KOS13607.1 - 0.0081 14.3 0.8 0.012 13.7 0.6 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector PHD PF00628.24 KOS13608.1 - 1e-09 37.8 9.3 2.3e-09 36.8 6.4 1.6 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KOS13608.1 - 0.0018 17.9 0.8 0.0046 16.6 0.5 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger PHD_2 PF13831.1 KOS13608.1 - 0.002 17.3 5.1 0.0045 16.2 3.6 1.6 1 0 0 1 1 1 1 PHD-finger Sugar_tr PF00083.19 KOS13609.1 - 4.1e-62 210.2 23.6 5.4e-62 209.8 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS13609.1 - 3.2e-13 49.1 48.5 1.5e-09 37.0 16.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily ARL6IP6 PF15062.1 KOS13609.1 - 1.4 8.8 3.8 1.4 8.8 0.5 2.6 2 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix PPR_2 PF13041.1 KOS13610.1 - 0.12 12.3 0.0 2 8.4 0.0 2.9 2 1 0 2 2 2 0 PPR repeat family PDH PF02153.12 KOS13611.1 - 4.2e-14 52.0 0.0 6.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KOS13611.1 - 7.7e-08 32.3 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KOS13611.1 - 2.2e-07 31.2 0.0 6.8e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KOS13611.1 - 0.00078 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KOS13611.1 - 0.017 14.8 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.15 KOS13611.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KOS13611.1 - 0.074 12.7 0.0 0.29 10.7 0.0 1.7 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_B PF00136.16 KOS13612.1 - 7e-113 377.8 0.2 1.2e-112 377.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KOS13612.1 - 1.5e-47 161.4 0.7 2.5e-47 160.6 0.5 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 KOS13612.1 - 1.2e-22 79.5 1.7 3.1e-22 78.1 1.2 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 KOS13612.1 - 1.9e-17 63.1 0.0 2.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zinc_ribbon_5 PF13719.1 KOS13612.1 - 0.12 12.0 0.5 0.28 10.8 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.11 KOS13613.1 - 1.2e-10 40.8 9.8 2e-10 40.1 6.8 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 KOS13613.1 - 0.67 9.8 4.5 1.6 8.6 3.1 1.6 1 0 0 1 1 1 0 B-box zinc finger Transthyretin PF00576.16 KOS13614.1 - 1.8e-33 114.7 0.5 2e-33 114.5 0.3 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 KOS13614.1 - 0.014 15.4 0.3 0.02 14.9 0.2 1.4 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Sperm_Ag_HE2 PF05324.8 KOS13615.1 - 1.2 9.1 4.7 40 4.2 3.2 2.3 1 1 0 1 1 1 0 Sperm antigen HE2 Transp_cyt_pur PF02133.10 KOS13616.1 - 4.8e-112 374.7 32.4 5.7e-112 374.4 22.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 KOS13617.1 - 1.1e-119 399.9 38.8 1.3e-119 399.6 26.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SMC_Nse1 PF07574.8 KOS13618.1 - 8.8e-21 74.4 0.0 3.8e-18 65.8 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING_2 PF13639.1 KOS13618.1 - 0.00011 21.9 13.2 0.00023 20.9 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 KOS13618.1 - 0.00035 20.4 13.3 0.00036 20.4 8.3 1.7 2 0 0 2 2 2 1 RING-like domain zf-rbx1 PF12678.2 KOS13618.1 - 2.5 8.2 9.9 5.4 7.1 6.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Scm3 PF10384.4 KOS13619.1 - 2.6e-12 46.0 0.8 5.1e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 DUF4611 PF15387.1 KOS13619.1 - 0.023 14.8 1.9 0.043 13.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KOS13619.1 - 0.039 13.4 3.7 0.056 12.9 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 KOS13619.1 - 0.049 13.4 2.1 0.07 12.9 1.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 KOS13619.1 - 0.22 11.1 1.4 0.38 10.4 0.9 1.4 1 0 0 1 1 1 0 FAM176 family DUF4484 PF14831.1 KOS13619.1 - 0.71 9.9 4.6 0.92 9.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) CENP-B_dimeris PF09026.5 KOS13619.1 - 1.2 9.4 11.6 0.4 10.9 6.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rab5-bind PF09311.6 KOS13620.1 - 0.027 14.3 2.5 0.042 13.7 1.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein HrpJ PF07201.6 KOS13620.1 - 0.045 13.7 1.6 0.06 13.3 1.1 1.1 1 0 0 1 1 1 0 HrpJ-like domain MIS13 PF08202.6 KOS13620.1 - 0.076 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Herpes_UL79 PF03049.9 KOS13621.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 UL79 family Ribosomal_L27 PF01016.14 KOS13622.1 - 8.6e-31 105.5 1.4 1.3e-30 104.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Myb_DNA-bind_6 PF13921.1 KOS13623.1 - 0.0028 17.7 0.4 0.5 10.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SRP-alpha_N PF04086.8 KOS13623.1 - 0.059 12.7 0.8 0.24 10.7 0.6 2.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1751 PF08551.5 KOS13624.1 - 0.014 15.6 0.3 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KOS13624.1 - 0.074 13.0 2.1 0.13 12.2 1.4 1.5 1 0 0 1 1 1 0 Rhomboid family Peptidase_M16 PF00675.15 KOS13625.1 - 7.7e-19 67.9 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS13625.1 - 4e-17 62.4 0.0 9.9e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Allantoicase PF03561.10 KOS13626.1 - 3.3e-87 289.6 0.0 1.3e-44 151.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 KOS13626.1 - 4.6e-37 126.8 0.0 7e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase SHMT PF00464.14 KOS13627.1 - 8.1e-173 574.3 0.0 9.4e-173 574.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KOS13627.1 - 9e-06 25.0 0.0 2.7e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KOS13627.1 - 0.042 12.7 0.0 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II AMP-binding PF00501.23 KOS13628.1 - 4.3e-50 170.3 0.0 8.4e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KOS13628.1 - 4.5e-12 46.0 1.4 1.1e-11 44.8 1.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 KOS13628.1 - 8.5e-12 44.0 6.7 0.00026 20.3 0.0 7.0 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS13628.1 - 0.0088 15.5 7.0 3.5 7.2 0.0 5.4 6 0 0 6 6 6 1 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 KOS13628.1 - 0.73 8.2 0.1 9.5 4.6 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DnaJ-X PF14308.1 KOS13629.1 - 1.3e-62 210.7 0.0 1.3e-62 210.7 0.0 2.3 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KOS13629.1 - 4.4e-20 71.1 0.6 4.4e-20 71.1 0.4 2.8 3 0 0 3 3 3 1 DnaJ domain SAPS PF04499.10 KOS13629.1 - 0.078 11.5 7.2 0.011 14.3 2.3 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein NPIP PF06409.6 KOS13629.1 - 0.24 10.0 6.7 0.52 9.0 4.6 1.5 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DDHD PF02862.12 KOS13629.1 - 1.1 8.9 7.9 2.7 7.7 3.9 2.2 2 1 0 2 2 2 0 DDHD domain DUF913 PF06025.7 KOS13629.1 - 2.4 6.8 7.2 0.93 8.1 3.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MAPEG PF01124.13 KOS13630.1 - 4.9e-14 52.0 0.8 7.2e-14 51.5 0.6 1.3 1 1 0 1 1 1 1 MAPEG family ECH PF00378.15 KOS13631.1 - 7.5e-19 67.8 0.2 9.7e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Syja_N PF02383.13 KOS13632.1 - 2.5e-71 240.0 0.0 3.7e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KOS13632.1 - 2.7e-20 73.3 0.1 7.1e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3439 PF11921.3 KOS13632.1 - 4 7.2 12.8 9.2 6.0 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KOS13632.1 - 5.7 4.5 4.7 8.3 4.0 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CHORD PF04968.7 KOS13633.1 - 2.3e-44 149.4 13.0 1.1e-22 79.9 1.7 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KOS13633.1 - 1.3e-08 35.2 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.14 KOS13633.1 - 0.26 10.9 9.8 0.15 11.7 1.6 3.3 3 1 0 3 3 3 0 BTK motif zf-A20 PF01754.11 KOS13633.1 - 1.4 8.5 7.4 4 7.1 0.8 2.5 2 0 0 2 2 2 0 A20-like zinc finger zf-CCHC PF00098.18 KOS13634.1 - 6.4e-43 142.7 45.0 2.7e-08 33.3 1.8 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 KOS13634.1 - 2.1e-11 43.2 35.8 0.017 14.8 0.3 6.0 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 KOS13634.1 - 9.3e-10 38.0 24.1 0.18 11.5 0.1 6.1 1 1 5 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 KOS13634.1 - 5.2e-07 29.0 32.3 0.099 12.1 0.1 6.4 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 KOS13634.1 - 0.017 14.7 2.7 0.017 14.7 1.9 5.8 5 1 1 6 6 6 0 Zinc knuckle Exo_endo_phos PF03372.18 KOS13635.1 - 2.9e-20 73.2 0.4 3.7e-20 72.9 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KOS13635.1 - 1.3e-07 31.2 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_11 PF13414.1 KOS13636.1 - 5.3e-29 99.6 3.3 2.5e-21 75.0 0.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS13636.1 - 2.9e-27 93.1 0.6 2.9e-08 32.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13636.1 - 8.5e-22 75.2 0.5 2.3e-07 30.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS13636.1 - 5.6e-15 54.2 0.1 4e-08 32.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13636.1 - 1.7e-13 49.2 0.9 0.00066 19.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13636.1 - 7.4e-12 45.6 0.1 3.4e-05 24.3 0.0 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13636.1 - 9.1e-12 44.5 0.1 0.00026 21.3 0.0 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13636.1 - 1.1e-10 41.2 1.8 1e-07 31.7 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13636.1 - 1.9e-10 40.9 0.1 7.3e-06 26.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13636.1 - 1e-09 37.4 0.0 3e-05 23.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS13636.1 - 1.1e-06 28.4 0.0 0.00054 19.7 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 KOS13636.1 - 0.00012 22.4 0.1 0.00034 20.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_4 PF07721.9 KOS13636.1 - 0.0002 21.4 0.2 0.062 13.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KOS13636.1 - 0.00037 20.5 1.1 0.0079 16.3 0.1 1.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KOS13636.1 - 0.00044 20.0 0.2 1.1 9.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KOS13636.1 - 0.0013 17.8 0.1 0.0062 15.6 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13636.1 - 0.0037 17.6 4.3 5.9 7.5 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KOS13636.1 - 0.017 13.8 2.0 0.29 9.8 0.4 2.2 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 MIT PF04212.13 KOS13636.1 - 1.1 9.2 8.5 1.9 8.4 0.1 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain GTP_EFTU PF00009.22 KOS13637.1 - 3.7e-41 140.6 0.0 5.7e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KOS13637.1 - 1.3e-24 86.0 0.0 2.6e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KOS13637.1 - 2.6e-21 75.2 0.0 9e-21 73.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 KOS13637.1 - 2.4e-07 31.2 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS13637.1 - 3.2e-07 30.3 0.0 5.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KOS13637.1 - 1.6e-06 28.1 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KOS13637.1 - 8.1e-06 25.6 0.1 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.18 KOS13637.1 - 0.029 14.2 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Ras PF00071.17 KOS13637.1 - 0.13 11.6 0.0 0.45 9.8 0.0 1.8 1 1 0 1 1 1 0 Ras family SRPRB PF09439.5 KOS13637.1 - 0.14 11.3 0.0 0.51 9.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Rapsyn_N PF10579.4 KOS13637.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region ADH_zinc_N PF00107.21 KOS13638.1 - 1.6e-11 43.8 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS13638.1 - 8.5e-05 22.2 0.1 0.00021 21.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 KOS13639.1 - 2.4e-52 177.6 0.0 3.6e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13639.1 - 2.4e-48 164.4 0.0 3.1e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Nitroreductase PF00881.19 KOS13639.1 - 1.3e-12 47.8 0.1 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family APH PF01636.18 KOS13639.1 - 0.014 15.1 0.2 0.099 12.3 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 KOS13640.1 - 5.2e-17 61.0 0.6 9.1e-05 22.1 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS13640.1 - 0.048 12.4 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like Ran_BP1 PF00638.13 KOS13641.1 - 6.6e-10 39.0 0.1 1.4e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain CLASP_N PF12348.3 KOS13642.1 - 1.1e-61 208.1 1.9 2e-57 194.1 0.3 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.1 KOS13642.1 - 1.1e-08 35.2 13.6 8.4e-05 22.7 0.2 5.4 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KOS13642.1 - 1.2e-07 31.1 4.1 0.43 10.7 0.0 5.4 4 0 0 4 4 4 3 HEAT repeat MMS19_C PF12460.3 KOS13642.1 - 0.0036 16.1 0.1 0.99 8.0 0.0 2.4 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 KOS13642.1 - 0.0042 17.5 6.7 14 6.3 0.0 4.9 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KOS13642.1 - 0.11 12.3 0.1 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KOS13642.1 - 0.13 12.2 0.3 5.2 7.1 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion ERCC4 PF02732.10 KOS13643.1 - 1.3e-25 89.8 0.0 2.5e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KOS13643.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain SSF PF00474.12 KOS13644.1 - 8.1e-08 31.3 15.1 3.4e-07 29.2 10.5 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family DUF1279 PF06916.8 KOS13644.1 - 0.1 12.8 0.3 0.39 11.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Tombus_P33 PF08500.5 KOS13644.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus p33 Aldo_ket_red PF00248.16 KOS13645.1 - 2.3e-31 108.6 0.0 1e-30 106.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family tRNA_int_endo PF01974.12 KOS13646.1 - 1.8e-21 75.7 0.0 3.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KOS13646.1 - 2.3e-06 27.0 0.0 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain RCC1 PF00415.13 KOS13647.1 - 5.2e-23 81.0 14.8 7.5e-05 22.8 0.1 7.1 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS13647.1 - 6.7e-21 73.3 24.8 6.2e-09 35.2 0.5 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Polysacc_deac_1 PF01522.16 KOS13648.1 - 2.2e-13 49.8 0.0 3.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PX PF00787.19 KOS13649.1 - 7.5e-13 48.2 0.0 2e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 PX domain PhzC-PhzF PF02567.11 KOS13650.1 - 2.6e-41 141.7 0.0 3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 KOS13650.1 - 0.0016 17.3 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Proline racemase CwfJ_C_1 PF04677.10 KOS13651.1 - 1.9e-28 98.5 0.0 3.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KOS13651.1 - 1.5e-16 60.6 0.0 4.4e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF1777 PF08648.7 KOS13651.1 - 0.0011 18.7 29.2 0.0011 18.7 20.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) Ribosomal_S4e PF00900.15 KOS13652.1 - 4.6e-31 106.3 0.2 1.1e-30 105.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KOS13652.1 - 1.3e-17 63.3 3.8 1.3e-17 63.3 2.7 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 KOS13652.1 - 0.0011 18.3 0.9 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 KOS13652.1 - 0.0011 18.5 2.8 0.0026 17.4 0.5 2.5 2 0 0 2 2 2 1 KOW motif Pkinase PF00069.20 KOS13653.1 - 2e-56 191.0 0.0 2.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13653.1 - 1.5e-21 76.6 0.0 3.2e-21 75.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS13653.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase VHS PF00790.14 KOS13654.1 - 2.8e-36 124.2 0.8 2.8e-36 124.2 0.6 1.6 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 KOS13654.1 - 2.1e-14 52.8 1.1 3.8e-14 52.0 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KOS13654.1 - 3.5e-14 51.9 0.1 7.1e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS13654.1 - 3.4e-13 48.8 0.1 5.7e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KOS13654.1 - 0.0016 18.3 1.1 0.0016 18.3 0.7 2.8 3 0 0 3 3 3 1 GAT domain UIM PF02809.15 KOS13654.1 - 0.0038 16.6 3.7 0.0038 16.6 2.6 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif Hrs_helical PF12210.3 KOS13654.1 - 0.016 15.4 1.6 0.016 15.4 1.1 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DivIVA PF05103.8 KOS13654.1 - 0.42 10.6 2.9 13 5.8 0.5 2.6 2 0 0 2 2 2 0 DivIVA protein bZIP_C PF12498.3 KOS13654.1 - 0.83 10.8 10.7 0.81 10.9 2.0 2.6 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Ribosomal_L2_C PF03947.13 KOS13655.1 - 4e-41 139.8 9.1 2.4e-40 137.3 1.6 2.8 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KOS13655.1 - 5.1e-26 90.4 0.4 5.1e-26 90.4 0.3 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RPN7 PF10602.4 KOS13656.1 - 1.2e-44 151.7 0.3 1.9e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KOS13656.1 - 1.6e-13 50.8 0.0 4.7e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 KOS13656.1 - 5e-05 22.9 0.1 0.086 12.7 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.3 KOS13656.1 - 0.0042 15.9 1.4 0.019 13.7 0.1 2.0 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 Thiolase_N PF00108.18 KOS13657.1 - 6.7e-87 290.8 1.8 6.7e-87 290.8 1.3 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS13657.1 - 1.1e-42 144.3 0.8 1.1e-42 144.3 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KOS13657.1 - 5.7e-05 22.7 1.9 0.00036 20.0 0.1 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain MatE PF01554.13 KOS13658.1 - 2e-45 154.3 29.8 2.9e-27 95.2 8.1 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KOS13658.1 - 6.5e-06 26.0 21.8 1.2e-05 25.1 6.9 3.9 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Histone PF00125.19 KOS13659.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KOS13659.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KOS13659.1 - 0.00033 20.5 0.1 0.00047 20.0 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KOS13659.1 - 0.00039 20.4 0.1 0.00079 19.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KOS13659.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Skp1 PF01466.14 KOS13660.1 - 7.7e-40 134.8 1.2 1.3e-39 134.0 0.9 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KOS13660.1 - 2.9e-24 84.9 0.3 5.7e-24 83.9 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 KOS13660.1 - 0.014 15.4 0.1 0.29 11.1 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain UCH PF00443.24 KOS13661.1 - 2.3e-78 263.0 0.0 3.4e-78 262.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS13661.1 - 5.7e-21 75.2 0.0 2.5e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KOS13661.1 - 3.4e-07 30.5 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 DUSP domain DEAD PF00270.24 KOS13662.1 - 2.7e-45 153.8 0.0 8.3e-45 152.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KOS13662.1 - 3.4e-23 80.9 0.1 9.6e-23 79.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KOS13662.1 - 5.7e-21 74.1 0.0 1.7e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS13662.1 - 0.00093 19.0 0.0 0.0095 15.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Aha1_N PF09229.6 KOS13663.1 - 1.1e-32 112.7 0.1 1.6e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KOS13663.1 - 1.5e-17 63.8 0.0 4.1e-17 62.4 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KOS13663.1 - 0.00027 21.1 0.0 0.00089 19.4 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Hc1 PF07432.8 KOS13663.1 - 0.095 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Histone H1-like protein Hc1 ArgJ PF01960.13 KOS13664.1 - 3e-127 424.2 0.1 3.4e-127 424.0 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Zip PF02535.17 KOS13665.1 - 1.4e-55 188.5 5.3 1.5e-55 188.4 3.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter PCI PF01399.22 KOS13666.1 - 4.4e-20 71.9 3.9 1.8e-19 69.9 0.2 2.5 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 KOS13666.1 - 0.006 15.9 1.3 0.032 13.5 0.1 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 KOS13666.1 - 0.15 11.9 4.6 22 5.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13666.1 - 1.6 9.5 10.6 6.2 7.6 0.4 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 KOS13667.1 - 6.6e-14 51.7 0.1 1.7e-13 50.3 0.1 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS13667.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DnaJ PF00226.26 KOS13668.1 - 4.1e-19 68.0 0.9 1.4e-18 66.4 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain 2-Hacid_dh_C PF02826.14 KOS13669.1 - 5e-44 149.5 0.0 4.7e-41 139.8 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS13669.1 - 2.7e-24 85.1 0.0 3.8e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS13669.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KOS13669.1 - 0.0044 17.4 0.0 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent BAG PF02179.11 KOS13670.1 - 2.8e-12 46.5 0.3 1.6e-11 44.1 0.2 2.0 1 1 0 1 1 1 1 BAG domain zf-TFIIIC PF12660.2 KOS13670.1 - 8.6e-11 41.6 2.7 2.1e-10 40.3 1.9 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ubiquitin PF00240.18 KOS13670.1 - 2.5e-06 26.8 0.0 6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TFIIIC_delta PF12657.2 KOS13670.1 - 4.7e-06 26.4 0.8 1.3e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KOS13670.1 - 7.4e-05 22.4 0.4 0.0028 17.4 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat PAT1 PF09770.4 KOS13670.1 - 6.1 4.9 17.3 8.3 4.5 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Use1 PF09753.4 KOS13672.1 - 8.5e-10 38.4 0.1 3.6e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Membrane fusion protein Use1 HWE_HK PF07536.9 KOS13672.1 - 5.6 7.4 7.7 6.1 7.3 0.5 2.8 2 1 1 3 3 3 0 HWE histidine kinase ubiquitin PF00240.18 KOS13673.1 - 2.4e-17 62.0 2.0 3.1e-14 52.0 1.4 3.0 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS13673.1 - 5e-09 35.7 0.6 1.4e-06 27.8 0.4 2.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KOS13673.1 - 0.00011 22.3 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain TAP42 PF04177.7 KOS13675.1 - 1.4e-57 195.1 0.3 1.7e-57 194.9 0.2 1.0 1 0 0 1 1 1 1 TAP42-like family DHH PF01368.15 KOS13676.1 - 7.4e-07 28.9 0.1 4.1e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 KOS13676.1 - 4.4e-05 23.6 0.0 0.00031 20.9 0.0 2.3 1 1 0 1 1 1 1 DHHA2 domain HECT PF00632.20 KOS13677.1 - 8.7e-73 245.2 0.0 1.4e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2454 PF10521.4 KOS13677.1 - 0.0061 15.5 0.0 0.013 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Alg14 PF08660.6 KOS13678.1 - 2.3e-43 148.1 0.0 2.8e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ubiquitin PF00240.18 KOS13679.1 - 2e-24 84.7 0.2 3.2e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KOS13679.1 - 1.7e-11 43.6 0.0 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 KOS13679.1 - 3.7e-10 39.5 7.1 7.9e-10 38.4 4.9 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger zf-CSL PF05207.8 KOS13679.1 - 0.011 15.1 0.5 0.026 14.0 0.3 1.7 1 0 0 1 1 1 0 CSL zinc finger Ubiquitin_2 PF14560.1 KOS13679.1 - 0.018 15.3 0.1 0.076 13.2 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KOS13679.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 KOS13679.1 - 0.08 12.8 3.1 0.14 12.0 2.2 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 KOS13679.1 - 0.092 12.7 0.1 0.33 11.0 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) ELO PF01151.13 KOS13680.1 - 1.1e-52 178.8 25.5 1.3e-52 178.6 17.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 KOS13681.1 - 1e-54 185.5 21.8 1.3e-54 185.1 15.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kei1 PF08552.6 KOS13682.1 - 1.1e-40 139.3 1.0 1.8e-40 138.6 0.7 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 dsDNA_bind PF01984.15 KOS13682.1 - 7.6e-26 90.1 8.4 1.9e-25 88.9 5.8 1.7 1 1 0 1 1 1 1 Double-stranded DNA-binding domain PX PF00787.19 KOS13683.1 - 8e-19 67.5 0.1 2.7e-18 65.7 0.0 1.9 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 KOS13683.1 - 5.9e-10 38.7 7.6 2.9e-05 23.4 2.3 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KOS13683.1 - 0.0015 18.0 9.8 0.0075 15.7 1.2 2.2 2 0 0 2 2 2 2 BAR domain BAR_3_WASP_bdg PF10456.4 KOS13683.1 - 0.0016 17.7 1.0 0.09 12.0 0.2 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein Dsl1_N PF11988.3 KOS13683.1 - 0.008 15.0 0.4 0.016 14.1 0.3 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal DUF4407 PF14362.1 KOS13683.1 - 0.18 10.7 6.5 0.29 10.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.6 KOS13683.1 - 2 8.2 8.1 2.8 7.8 0.0 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.10 KOS13683.1 - 3.3 6.8 11.4 1.7 7.7 6.4 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.3 KOS13683.1 - 6.7 3.8 17.7 0.46 7.7 8.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PEP-utilisers_N PF05524.8 KOS13683.1 - 8.9 6.1 14.2 4.6 7.0 2.2 3.7 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Aminotran_1_2 PF00155.16 KOS13684.1 - 3.1e-72 243.5 0.0 3.5e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2_jaz PF12171.3 KOS13685.1 - 7.4e-09 35.5 0.2 5.9e-08 32.6 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS13685.1 - 4.6e-05 23.4 0.5 8.7e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS13685.1 - 0.0042 17.1 0.2 0.0063 16.5 0.2 1.3 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KOS13685.1 - 0.027 14.8 1.7 0.069 13.5 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS13685.1 - 0.048 14.0 0.9 0.11 12.8 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type AAA PF00004.24 KOS13686.1 - 8.9e-18 64.7 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KOS13686.1 - 1.7e-15 56.7 0.1 4.1e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KOS13686.1 - 4.5e-14 52.4 0.0 3.8e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KOS13686.1 - 3.2e-12 45.9 0.0 2.3e-09 36.5 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS13686.1 - 4.6e-07 30.0 0.8 2.6e-05 24.3 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KOS13686.1 - 5.9e-07 29.6 0.5 0.00013 22.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KOS13686.1 - 2.2e-06 26.8 0.0 6.9e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KOS13686.1 - 4.4e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KOS13686.1 - 4.5e-06 26.3 0.0 1.1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KOS13686.1 - 7.4e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS13686.1 - 1.1e-05 25.1 0.2 4.1e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KOS13686.1 - 6.5e-05 22.6 0.0 0.0004 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KOS13686.1 - 6.9e-05 21.8 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 KOS13686.1 - 8.1e-05 23.0 0.0 0.00021 21.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS13686.1 - 0.00029 20.2 0.1 0.00072 19.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KOS13686.1 - 0.00082 18.9 0.0 0.0021 17.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KOS13686.1 - 0.00087 19.1 0.0 0.011 15.6 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KOS13686.1 - 0.00089 20.0 0.0 0.0021 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KOS13686.1 - 0.0013 18.3 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 KOS13686.1 - 0.0016 18.0 1.3 0.005 16.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 KOS13686.1 - 0.002 17.6 0.3 0.025 14.1 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 KOS13686.1 - 0.0021 17.5 0.6 1.9 7.8 0.1 2.4 1 1 1 2 2 2 2 AAA-like domain AAA_28 PF13521.1 KOS13686.1 - 0.0044 16.9 0.2 0.016 15.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS13686.1 - 0.0046 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KOS13686.1 - 0.0084 15.2 0.0 0.065 12.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS13686.1 - 0.0099 16.0 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 KOS13686.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KOS13686.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 KOS13686.1 - 0.014 14.7 0.3 0.06 12.7 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 KOS13686.1 - 0.015 14.2 0.1 0.036 13.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KOS13686.1 - 0.023 14.1 0.0 0.067 12.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KOS13686.1 - 0.027 14.7 0.0 0.079 13.2 0.0 1.9 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 KOS13686.1 - 0.038 13.4 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 KOS13686.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thioredoxin PF00085.15 KOS13687.1 - 5.7e-54 180.1 0.1 4.4e-26 90.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KOS13687.1 - 1.8e-19 70.1 0.1 5.1e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KOS13687.1 - 9.8e-15 54.7 0.3 4.7e-06 26.7 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS13687.1 - 2.5e-12 46.7 0.2 1.3e-05 25.2 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS13687.1 - 3.1e-11 43.1 0.0 7.4e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KOS13687.1 - 1.3e-10 41.0 0.1 7.6e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 KOS13687.1 - 7.4e-08 32.4 0.0 9.1e-07 28.8 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 KOS13687.1 - 4.7e-06 26.1 0.3 0.085 12.3 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 KOS13687.1 - 0.001 19.1 0.2 0.33 10.9 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 KOS13687.1 - 0.0075 16.1 0.0 0.92 9.4 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DDE_Tnp_1_2 PF13586.1 KOS13687.1 - 0.052 13.7 0.0 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Transposase DDE domain Mu-like_Com PF10122.4 KOS13687.1 - 0.11 11.5 2.5 7.1 5.7 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Abhydrolase_5 PF12695.2 KOS13688.1 - 5.8e-05 22.8 0.4 0.00029 20.6 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS13688.1 - 0.022 14.6 0.4 0.073 12.9 0.1 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF1749 PF08538.5 KOS13688.1 - 0.045 12.6 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 KOS13688.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) CUE PF02845.11 KOS13689.1 - 2.2e-11 43.0 0.0 4.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain Mito_carr PF00153.22 KOS13690.1 - 2e-28 97.9 2.8 6.7e-16 57.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SAC3_GANP PF03399.11 KOS13691.1 - 5.1e-68 228.6 2.6 6.5e-68 228.3 1.8 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KOS13691.1 - 5.9e-06 26.1 1.4 8e-06 25.6 0.3 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ARL6IP6 PF15062.1 KOS13691.1 - 0.16 11.8 0.3 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Glutaredoxin PF00462.19 KOS13692.1 - 9.3e-19 67.1 0.1 4.5e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KOS13692.1 - 1.2e-13 50.6 0.0 2.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KOS13692.1 - 1.9e-05 24.6 0.1 0.0011 19.0 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like GST_N_3 PF13417.1 KOS13692.1 - 0.0016 18.6 0.0 0.0049 17.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Phosducin PF02114.11 KOS13692.1 - 0.0021 16.8 0.0 0.0042 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosducin Thioredoxin_3 PF13192.1 KOS13692.1 - 0.01 15.6 0.1 0.48 10.2 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain SH3BGR PF04908.10 KOS13692.1 - 0.022 14.7 0.2 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein TrbC_Ftype PF09673.5 KOS13692.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein ArsC PF03960.10 KOS13692.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 ArsC family IGPD PF00475.13 KOS13693.1 - 2.2e-61 205.9 0.7 2.8e-61 205.6 0.5 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF3535 PF12054.3 KOS13694.1 - 1.1e-80 271.4 8.0 2.8e-79 266.8 3.5 3.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KOS13694.1 - 1.2e-71 241.0 0.0 1.9e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS13694.1 - 1.8e-12 46.9 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KOS13694.1 - 9.8e-11 40.8 25.2 0.034 14.2 0.1 11.1 10 1 1 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KOS13694.1 - 4e-06 27.1 0.2 0.073 13.4 0.1 3.5 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HDA2-3 PF11496.3 KOS13694.1 - 0.0031 16.3 0.1 0.006 15.4 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Ipi1_N PF12333.3 KOS13694.1 - 0.014 15.3 1.9 7.3 6.6 0.0 3.9 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Tim44 PF04280.10 KOS13695.1 - 1.3e-29 103.1 0.2 1.2e-28 99.8 0.0 2.5 3 0 0 3 3 3 1 Tim44-like domain Seryl_tRNA_N PF02403.17 KOS13695.1 - 0.05 13.6 2.3 0.091 12.7 1.3 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SQS_PSY PF00494.14 KOS13695.1 - 0.11 11.8 4.7 1.4 8.1 0.1 3.0 2 1 0 3 3 3 0 Squalene/phytoene synthase TPT PF03151.11 KOS13696.1 - 1.1e-32 112.7 12.4 1.1e-32 112.7 8.6 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KOS13696.1 - 1.3e-15 57.1 18.0 1.6e-15 56.8 12.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS13696.1 - 2.6e-15 56.5 28.1 6.2e-10 39.2 6.6 2.6 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KOS13696.1 - 1.8e-06 27.2 9.5 0.00044 19.4 0.3 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KOS13696.1 - 0.006 16.7 23.5 0.0063 16.7 3.6 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 KOS13696.1 - 0.34 10.7 8.9 2.5 7.9 1.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Multi_Drug_Res PF00893.14 KOS13696.1 - 1.1 9.8 10.9 0.2 12.1 2.2 2.8 2 1 0 2 2 2 0 Small Multidrug Resistance protein Bac_export_2 PF01312.14 KOS13696.1 - 3.9 6.2 10.2 0.13 11.1 1.9 2.0 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family RRM_6 PF14259.1 KOS13697.1 - 1.3e-12 47.5 0.0 2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS13697.1 - 1.7e-12 46.7 0.0 2.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13697.1 - 2.7e-06 27.1 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MR_MLE PF01188.16 KOS13697.1 - 0.085 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Cupin_8 PF13621.1 KOS13698.1 - 1.9e-09 37.4 0.0 4.5e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS13698.1 - 1.2e-07 31.9 2.6 1.8e-06 28.1 0.1 3.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.24 KOS13698.1 - 2.9e-06 26.8 8.9 6.4e-06 25.7 6.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KOS13698.1 - 0.0013 18.4 6.2 0.003 17.2 4.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 KOS13698.1 - 0.016 15.2 1.4 0.034 14.1 1.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KOS13698.1 - 0.022 14.9 2.2 0.041 14.0 1.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Siva PF05458.7 KOS13698.1 - 0.23 11.0 2.4 0.43 10.1 1.6 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PHD_2 PF13831.1 KOS13698.1 - 0.47 9.8 9.6 1.2 8.4 6.7 1.7 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.10 KOS13698.1 - 2 8.2 8.2 0.92 9.2 3.0 2.3 2 0 0 2 2 2 0 CW-type Zinc Finger zf-RING_2 PF13639.1 KOS13698.1 - 2.2 8.1 7.0 0.62 9.9 2.6 1.8 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_5 PF13719.1 KOS13698.1 - 8.3 6.0 9.8 1.1e+02 2.4 6.0 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Glyco_transf_8 PF01501.15 KOS13699.1 - 6.4e-22 78.1 0.0 8.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 DEAD PF00270.24 KOS13700.1 - 6.7e-21 74.5 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13700.1 - 3.2e-20 71.7 0.1 3.5e-18 65.2 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KOS13700.1 - 1e-16 60.5 0.1 2.3e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 KOS13700.1 - 0.071 12.9 0.0 0.39 10.5 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS13700.1 - 0.076 12.5 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain PfUIS3 PF11567.3 KOS13700.1 - 0.13 12.3 0.1 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein Pyr_redox_2 PF07992.9 KOS13701.1 - 2.5e-19 69.9 0.0 3.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS13701.1 - 2.8e-14 53.2 0.0 5.2e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KOS13701.1 - 7.3e-10 38.8 0.1 0.00011 22.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KOS13701.1 - 1.3e-08 33.5 1.1 0.00019 20.4 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KOS13701.1 - 6.8e-08 31.7 3.0 0.0023 17.6 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KOS13701.1 - 2e-06 26.8 1.8 0.00091 18.4 0.7 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KOS13701.1 - 1.1e-05 24.9 0.6 0.00025 20.5 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain pair Pyr_redox_3 PF13738.1 KOS13701.1 - 0.00015 21.8 0.4 1.4 8.9 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.4 KOS13701.1 - 0.0048 16.9 1.8 1.1 9.2 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Vg_Tdu PF07545.9 KOS13701.1 - 0.071 12.5 2.7 0.21 11.0 0.9 2.3 2 0 0 2 2 2 0 Vestigial/Tondu family Fer2 PF00111.22 KOS13702.1 - 3.1e-11 42.8 0.3 4.8e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SKN1 PF03935.10 KOS13703.1 - 1.1e-179 597.8 4.0 1.4e-179 597.4 2.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Nitroreductase PF00881.19 KOS13704.1 - 2.7e-08 33.8 0.0 3.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family ECH PF00378.15 KOS13705.1 - 2.3e-19 69.4 0.0 2.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4364 PF14277.1 KOS13705.1 - 0.032 13.8 0.0 0.08 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) DUF566 PF04484.7 KOS13706.1 - 4.3 6.7 11.1 5.1 6.5 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aa_trans PF01490.13 KOS13707.1 - 5.6e-75 252.3 24.1 8e-75 251.8 13.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KOS13707.1 - 1.2e-06 27.6 12.8 1.2e-06 27.6 8.9 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Cytochrom_C_asm PF01578.15 KOS13707.1 - 0.17 11.4 6.8 3 7.3 4.7 2.4 1 1 0 1 1 1 0 Cytochrome C assembly protein Ank_2 PF12796.2 KOS13708.1 - 3.5e-12 46.4 1.0 1.2e-06 28.7 0.0 3.3 2 1 2 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS13708.1 - 3.2e-11 43.4 1.7 4.2e-05 23.9 0.1 3.2 4 0 0 4 4 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS13708.1 - 2.6e-10 40.2 1.7 1.5e-05 25.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS13708.1 - 6.1e-10 38.4 5.7 4.2e-06 26.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KOS13708.1 - 7e-09 35.0 1.6 0.00027 20.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KOS13708.1 - 7.6e-05 22.3 0.1 0.00038 20.0 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain IncA PF04156.9 KOS13708.1 - 0.013 15.0 0.8 0.027 14.0 0.6 1.4 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 KOS13708.1 - 0.067 12.1 1.7 0.14 11.0 1.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KOS13708.1 - 0.12 12.3 0.7 0.27 11.2 0.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KOS13708.1 - 0.22 10.1 1.9 0.35 9.4 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mt_ATP-synt_B PF05405.9 KOS13708.1 - 0.27 10.7 3.3 0.56 9.6 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AAA_13 PF13166.1 KOS13708.1 - 0.39 9.1 0.8 0.59 8.5 0.5 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KOS13708.1 - 7.2 6.2 6.4 4.2 6.9 2.8 1.7 2 0 0 2 2 2 0 Mnd1 family Ribosomal_S17e PF00833.13 KOS13709.1 - 1.9e-57 192.3 0.0 2.3e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_L14e PF01929.12 KOS13710.1 - 1.1e-27 96.1 4.7 1.6e-27 95.6 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KOS13710.1 - 0.025 14.3 0.8 0.052 13.2 0.6 1.6 1 0 0 1 1 1 0 KOW motif Histone PF00125.19 KOS13711.1 - 4.2e-30 103.6 0.7 6.4e-30 103.0 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KOS13711.1 - 3.5e-05 23.8 0.0 5.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KOS13711.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KOS13711.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated SnoaL_2 PF12680.2 KOS13712.1 - 0.053 13.9 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Glyoxalase_4 PF13669.1 KOS13713.1 - 1.5e-11 44.2 0.5 4.1e-10 39.6 0.1 2.0 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KOS13713.1 - 1.1e-10 42.1 0.0 1.6e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KOS13713.1 - 2.8e-09 37.0 0.2 4.9e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KOS13713.1 - 0.0081 16.0 0.0 0.065 13.1 0.0 2.0 1 1 0 2 2 2 1 Glyoxalase-like domain CppA_C PF14507.1 KOS13713.1 - 0.023 14.8 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 CppA C-terminal TLD PF07534.11 KOS13714.1 - 9.8e-24 83.9 0.0 1.8e-22 79.8 0.0 2.5 1 1 0 1 1 1 1 TLD zf-Nse PF11789.3 KOS13715.1 - 8e-16 57.3 0.0 1.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KOS13715.1 - 0.00017 21.2 0.1 0.00029 20.4 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 KOS13715.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain Arm PF00514.18 KOS13715.1 - 0.058 13.2 0.2 14 5.6 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DNA_Packaging_2 PF11123.3 KOS13715.1 - 0.061 13.2 0.1 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 DNA packaging protein zf-MIZ PF02891.15 KOS13715.1 - 0.095 12.2 0.5 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 KOS13715.1 - 0.12 12.2 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain Sel1 PF08238.7 KOS13716.1 - 1.7e-13 50.7 21.0 5.8e-05 23.5 0.0 7.4 7 2 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.23 KOS13716.1 - 0.021 14.4 0.0 3.2 7.5 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13716.1 - 0.028 14.3 9.3 0.083 12.8 0.0 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13716.1 - 0.033 14.1 0.2 0.033 14.1 0.2 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KOS13716.1 - 0.14 12.0 5.5 1.7 8.5 0.1 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KOS13716.1 - 0.18 12.3 10.5 6.1 7.5 0.0 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13716.1 - 0.47 10.3 4.1 6.8 6.7 0.0 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13716.1 - 0.49 11.1 0.2 0.49 11.1 0.1 6.0 6 2 0 6 6 6 0 Tetratricopeptide repeat Pex14_N PF04695.8 KOS13717.1 - 1.8e-10 40.9 1.3 8e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Myb_DNA-binding PF00249.26 KOS13718.1 - 1.7e-09 37.5 0.8 3.8e-09 36.4 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS13718.1 - 0.014 15.5 1.2 0.038 14.0 0.8 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RhoGEF PF00621.15 KOS13719.1 - 5.4e-39 133.9 0.0 8.9e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Ins_P5_2-kin PF06090.7 KOS13720.1 - 4e-15 55.6 0.0 9.4e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 Inositol-pentakisphosphate 2-kinase Abhydrolase_6 PF12697.2 KOS13720.1 - 0.024 14.4 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RAP1 PF07218.6 KOS13720.1 - 0.31 9.0 3.8 0.47 8.5 2.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SRP19 PF01922.12 KOS13721.1 - 2.7e-19 69.5 0.1 4.3e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 SRP19 protein DUF3617 PF12276.3 KOS13721.1 - 1.6 8.1 9.0 0.094 12.1 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) Raptor_N PF14538.1 KOS13722.1 - 6.8e-62 207.8 0.0 1.6e-61 206.6 0.0 1.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KOS13722.1 - 1.9e-09 36.9 6.1 0.094 12.6 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 KOS13722.1 - 2.3e-06 27.1 13.5 0.021 14.8 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat BBS2_Mid PF14783.1 KOS13722.1 - 0.0024 17.6 0.0 4 7.2 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 KOS13722.1 - 0.0055 16.9 4.0 0.083 13.1 0.1 3.9 1 1 3 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KOS13722.1 - 0.067 13.7 11.2 0.058 13.8 1.1 4.8 3 1 1 4 4 4 0 HEAT-like repeat Cnd1 PF12717.2 KOS13722.1 - 0.085 12.7 0.3 7.7 6.3 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_11 PF13414.1 KOS13723.1 - 3.3e-51 170.7 22.8 3.2e-16 58.7 0.0 6.3 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KOS13723.1 - 2.1e-43 144.2 20.7 2.4e-06 26.8 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13723.1 - 4e-37 123.1 21.3 0.00012 21.6 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13723.1 - 1.4e-23 82.6 16.1 6.8e-13 48.3 0.0 6.4 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13723.1 - 9e-23 80.3 10.4 4.7e-05 23.9 0.0 6.6 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13723.1 - 1.3e-20 72.0 7.6 0.00081 19.8 0.3 9.4 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13723.1 - 1.8e-18 64.8 16.3 0.0044 16.6 0.0 8.7 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13723.1 - 1.8e-17 63.4 9.0 0.00052 20.3 0.0 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13723.1 - 1.7e-14 52.3 4.4 0.0025 17.4 0.0 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS13723.1 - 9e-13 47.3 4.3 0.2 11.9 0.0 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS13723.1 - 2.2e-07 30.6 10.2 0.014 15.2 0.0 6.3 6 1 3 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS13723.1 - 8.7e-06 25.7 12.3 0.006 16.7 0.8 4.5 3 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KOS13723.1 - 2.5e-05 24.4 13.4 1.8 9.1 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 KOS13723.1 - 0.015 15.2 6.1 0.26 11.2 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 KOS13723.1 - 0.046 14.2 0.3 0.27 11.8 0.0 2.6 2 0 0 2 2 2 0 Peptidase inhibitor I9 RPN7 PF10602.4 KOS13723.1 - 2.4 7.4 6.7 1.6 8.0 0.1 3.5 2 1 0 3 3 3 0 26S proteasome subunit RPN7 IPK PF03770.11 KOS13724.1 - 5.7e-52 176.2 0.0 1e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase VGCC_beta4Aa_N PF12052.3 KOS13724.1 - 0.2 11.5 5.2 0.9 9.4 3.6 2.2 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ras PF00071.17 KOS13725.1 - 2e-50 170.3 0.0 2.4e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS13725.1 - 1.3e-14 54.6 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS13725.1 - 9.2e-08 31.5 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_peptidase_2 PF04298.7 KOS13725.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PduV-EutP PF10662.4 KOS13725.1 - 0.087 12.3 0.0 1.6 8.2 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KOS13725.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KOS13725.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Phos_pyr_kin PF08543.7 KOS13726.1 - 1.5e-09 37.4 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KOS13726.1 - 6.1e-09 35.4 0.1 2.2e-07 30.3 0.0 2.6 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Y_phosphatase2 PF03162.8 KOS13727.1 - 8.5e-50 168.3 0.0 9.6e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KOS13727.1 - 1.5e-08 35.0 0.1 7.8e-07 29.4 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.15 KOS13727.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Kin17_mid PF10357.4 KOS13728.1 - 1.3e-45 154.1 0.1 2.5e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein DUF629 PF04780.7 KOS13728.1 - 0.0015 17.1 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.3 KOS13728.1 - 0.029 14.5 4.4 0.056 13.5 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KOS13728.1 - 0.03 14.4 1.3 0.097 12.7 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1604 PF07713.8 KOS13728.1 - 0.058 13.1 0.7 0.19 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) zf-met PF12874.2 KOS13728.1 - 0.072 13.3 4.4 0.14 12.3 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Cytochrom_C1 PF02167.10 KOS13729.1 - 1.8e-84 282.7 0.0 2.3e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KOS13729.1 - 0.0029 17.7 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III A_deaminase PF00962.17 KOS13730.1 - 3.2e-106 354.9 0.1 4.2e-106 354.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase FTH PF01827.22 KOS13730.1 - 0.17 11.5 0.6 5.1 6.6 0.0 2.6 3 0 0 3 3 3 0 FTH domain Mg_trans_NIPA PF05653.9 KOS13731.1 - 1.5e-103 345.8 15.8 1.8e-103 345.6 10.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KOS13731.1 - 1e-09 38.5 1.9 1e-09 38.5 1.3 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KOS13731.1 - 3.9e-05 23.6 7.1 3.9e-05 23.6 4.9 3.7 2 1 1 3 3 3 1 EamA-like transporter family RseC_MucC PF04246.7 KOS13731.1 - 6.3 6.3 12.3 3.6 7.1 0.1 3.5 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Flavoprotein PF02441.14 KOS13732.1 - 3.9e-41 139.7 0.1 5.4e-41 139.2 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Ribosomal_L35Ae PF01247.13 KOS13733.1 - 4.3e-41 138.5 0.3 4.9e-41 138.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KOS13733.1 - 0.0093 15.8 0.0 0.99 9.3 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain RhoGAP PF00620.22 KOS13734.1 - 5.8e-50 168.8 0.0 1e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KOS13734.1 - 3.3e-15 56.0 1.9 5.2e-15 55.3 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain YchF-GTPase_C PF06071.8 KOS13735.1 - 3.5e-34 116.4 0.1 7.5e-34 115.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KOS13735.1 - 1.9e-15 56.7 0.0 1.2e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS13735.1 - 1.5e-06 27.5 0.0 3.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 KOS13735.1 - 0.0016 18.7 1.1 2.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain BetaGal_dom3 PF13363.1 KOS13735.1 - 0.0026 17.1 0.1 0.0086 15.4 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 MobB PF03205.9 KOS13735.1 - 0.0039 16.8 0.4 2.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KOS13735.1 - 0.0079 17.0 0.5 0.065 14.0 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS13735.1 - 0.03 14.2 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KOS13736.1 - 9e-44 148.9 0.3 4.3e-43 146.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13736.1 - 1.7e-29 101.5 0.4 3.8e-29 100.3 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KOS13736.1 - 0.0018 16.7 0.0 0.019 13.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 KOS13736.1 - 0.0054 16.0 0.2 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain ResIII PF04851.10 KOS13736.1 - 0.0054 16.5 0.2 0.027 14.2 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KOS13736.1 - 0.0058 16.3 0.4 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KOS13736.1 - 0.019 15.0 0.3 0.077 13.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KOS13736.1 - 0.091 12.3 0.1 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 KOS13737.1 - 1.5e-141 472.3 9.0 1.9e-141 472.0 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_14 PF13173.1 KOS13737.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prp18 PF02840.10 KOS13738.1 - 8.9e-33 113.1 0.0 3.9e-31 107.8 0.0 2.2 1 1 1 2 2 2 2 Prp18 domain PRP4 PF08799.6 KOS13738.1 - 1.1e-10 40.5 3.0 1.1e-10 40.5 2.1 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like HSBP1 PF06825.7 KOS13739.1 - 6.8e-10 38.3 0.0 8.7e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Apolipoprotein PF01442.13 KOS13739.1 - 0.02 14.4 0.9 0.024 14.1 0.6 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CDC37_N PF03234.9 KOS13739.1 - 0.023 15.0 0.6 0.024 14.9 0.4 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1515 PF07439.6 KOS13739.1 - 0.037 13.8 0.1 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PLC-beta_C PF08703.5 KOS13739.1 - 0.038 13.7 0.1 0.04 13.6 0.1 1.0 1 0 0 1 1 1 0 PLC-beta C terminal MtrB PF05440.7 KOS13739.1 - 0.039 14.0 0.0 0.068 13.2 0.0 1.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Erythro-docking PF09277.6 KOS13739.1 - 0.041 13.5 0.5 0.61 9.8 0.0 2.1 1 1 1 2 2 2 0 Erythronolide synthase, docking IncA PF04156.9 KOS13739.1 - 0.048 13.2 0.3 0.057 13.0 0.2 1.1 1 0 0 1 1 1 0 IncA protein Tektin PF03148.9 KOS13739.1 - 0.051 12.1 0.2 0.056 11.9 0.2 1.2 1 0 0 1 1 1 0 Tektin family PhoU PF01895.14 KOS13739.1 - 0.058 13.8 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoU domain DELLA PF12041.3 KOS13739.1 - 0.066 12.8 1.5 6.2 6.5 0.1 2.2 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal YvrJ PF12841.2 KOS13739.1 - 0.067 12.5 0.3 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 YvrJ protein family Baculo_PEP_C PF04513.7 KOS13739.1 - 0.078 12.8 0.3 0.096 12.5 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_LP PF03363.8 KOS13739.1 - 0.079 12.5 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus leader protein DUF1484 PF07363.6 KOS13739.1 - 0.094 13.0 0.4 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) DUF883 PF05957.8 KOS13739.1 - 0.099 13.0 0.2 0.11 12.8 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2937 PF11157.3 KOS13739.1 - 0.1 11.9 0.4 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4200 PF13863.1 KOS13739.1 - 0.13 12.2 0.7 0.17 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4635 PF15466.1 KOS13739.1 - 0.13 11.5 0.2 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) FUSC PF04632.7 KOS13739.1 - 0.14 10.5 1.1 0.15 10.4 0.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.6 KOS13739.1 - 0.16 11.1 0.4 0.16 11.1 0.3 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spectrin PF00435.16 KOS13739.1 - 0.2 11.9 2.5 0.45 10.8 1.3 1.7 1 1 0 1 1 1 0 Spectrin repeat FlxA PF14282.1 KOS13739.1 - 1 9.3 5.0 2.1 8.3 3.4 1.5 1 1 0 1 1 1 0 FlxA-like protein MerR-DNA-bind PF09278.6 KOS13739.1 - 1.5 9.2 4.5 6.4 7.2 3.1 1.9 1 1 0 1 1 1 0 MerR, DNA binding NARP1 PF12569.3 KOS13740.1 - 3.4e-153 511.1 8.4 2.3e-138 462.1 4.6 2.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 KOS13740.1 - 7.9e-11 41.0 13.8 5.7e-05 22.7 0.0 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS13740.1 - 1.8e-10 40.2 11.6 0.018 14.6 0.1 6.4 5 1 0 6 6 6 3 TPR repeat TPR_16 PF13432.1 KOS13740.1 - 1.1e-07 32.3 23.5 0.0064 17.1 0.5 8.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13740.1 - 4e-06 26.1 0.8 0.0061 16.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS13740.1 - 2e-05 24.3 14.5 0.00015 21.5 0.5 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13740.1 - 2.5e-05 24.5 18.5 3.6 8.5 0.1 9.1 8 2 3 11 11 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KOS13740.1 - 4.4e-05 23.5 2.1 0.04 14.0 0.1 4.6 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KOS13740.1 - 0.00087 19.1 13.8 0.02 14.8 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13740.1 - 0.0045 16.6 7.9 0.048 13.4 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13740.1 - 0.0065 16.1 0.1 2 8.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13740.1 - 0.021 15.1 0.5 0.021 15.1 0.3 6.9 7 2 2 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS13740.1 - 0.03 14.1 0.2 16 5.4 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat HTH_Tnp_Mu_1 PF02316.11 KOS13740.1 - 0.03 14.0 0.3 0.26 10.9 0.0 2.4 2 0 0 2 2 2 0 Mu DNA-binding domain TPR_10 PF13374.1 KOS13740.1 - 3.8 7.5 7.3 5.1 7.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.4 KOS13741.1 - 6.2e-78 262.4 1.6 1.1e-77 261.5 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 KOS13741.1 - 1.5e-34 118.7 0.1 3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KOS13741.1 - 6.2e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS13741.1 - 3.9e-09 36.5 0.0 2e-08 34.2 0.0 2.3 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPR_11 PF13414.1 KOS13741.1 - 1.9e-05 24.2 15.0 0.00038 20.0 1.4 5.0 3 1 1 4 4 4 1 TPR repeat TPR_8 PF13181.1 KOS13741.1 - 8.9e-05 22.0 4.1 2.6 8.0 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13741.1 - 0.00012 21.7 16.3 0.094 12.6 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13741.1 - 0.00049 19.9 12.7 0.0065 16.3 1.3 3.6 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13741.1 - 0.00094 19.4 0.5 6.2 7.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13741.1 - 0.0034 18.0 2.3 0.62 10.8 0.2 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13741.1 - 0.013 15.2 12.9 1.8 8.5 0.1 5.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13741.1 - 0.076 12.6 17.8 0.083 12.5 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13741.1 - 0.59 10.9 6.9 14 6.6 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat UFD1 PF03152.9 KOS13742.1 - 7.6e-67 223.8 0.0 9.8e-67 223.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RNase_HII PF01351.13 KOS13744.1 - 7.3e-41 139.9 0.0 7.9e-36 123.5 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease HII Abhydrolase_1 PF00561.15 KOS13745.1 - 1.7e-20 73.6 0.0 2.5e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS13745.1 - 1.9e-12 47.5 1.2 4.7e-11 43.0 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS13745.1 - 0.00048 19.9 0.1 0.027 14.2 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS13745.1 - 0.11 11.9 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Methyltransf_6 PF03737.10 KOS13746.1 - 6.7e-27 94.2 0.1 1.9e-25 89.5 0.1 2.1 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase DUF3449 PF11931.3 KOS13747.1 - 7.5e-64 214.8 0.3 3.3e-63 212.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 KOS13747.1 - 5.8e-06 26.3 4.9 8.6e-05 22.5 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KOS13747.1 - 1.1e-05 25.3 8.9 0.0001 22.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 KOS13747.1 - 0.0028 17.1 1.1 0.0053 16.2 0.7 1.4 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain FANCF PF11107.3 KOS13747.1 - 0.0061 15.8 0.4 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Fanconi anemia group F protein (FANCF) zf-C2H2_2 PF12756.2 KOS13747.1 - 0.016 15.2 1.1 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Hormone_3 PF00159.13 KOS13747.1 - 0.095 12.7 0.3 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Pancreatic hormone peptide zf-DBF PF07535.7 KOS13747.1 - 0.34 10.6 4.6 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 DBF zinc finger AhpC-TSA PF00578.16 KOS13748.1 - 3.2e-25 88.1 0.0 4.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS13748.1 - 2.5e-16 59.5 0.0 3.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin PLRV_ORF5 PF01690.12 KOS13748.1 - 0.004 16.3 0.4 0.0045 16.2 0.3 1.0 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein COX6B PF02297.12 KOS13749.1 - 3.7e-16 58.9 6.2 4.6e-16 58.6 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KOS13749.1 - 0.043 13.7 1.0 0.11 12.4 0.7 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 KOS13749.1 - 2 8.2 7.1 3.7 7.4 4.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Abhydrolase_6 PF12697.2 KOS13750.1 - 7e-12 45.7 1.0 9.8e-12 45.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS13750.1 - 1.4e-10 41.0 0.0 2.7e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS13750.1 - 1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KOS13750.1 - 1.8e-05 24.4 0.9 0.00016 21.3 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 KOS13750.1 - 0.015 13.8 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KOS13750.1 - 0.03 13.5 0.0 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TauD PF02668.11 KOS13751.1 - 6.2e-53 180.0 0.3 7.7e-53 179.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L18e PF00828.14 KOS13752.1 - 5.5e-23 81.7 0.0 1.3e-22 80.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Thioredoxin_8 PF13905.1 KOS13753.1 - 1.1e-05 25.4 0.3 0.0001 22.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KOS13753.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KOS13753.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1647 PF07801.6 KOS13753.1 - 0.044 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Apolipoprotein PF01442.13 KOS13754.1 - 8e-05 22.2 0.9 0.0016 17.9 0.6 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3811 PF11656.3 KOS13754.1 - 0.057 13.4 2.7 0.063 13.3 0.2 2.2 2 0 0 2 2 2 0 YjbD family (DUF3811) Phasin PF05597.6 KOS13754.1 - 0.089 12.5 1.6 3.2 7.5 0.9 2.8 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1690 PF07956.6 KOS13755.1 - 5.3e-12 45.9 7.0 6.8e-12 45.5 4.9 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CCDC92 PF14916.1 KOS13755.1 - 0.0057 16.2 2.1 0.012 15.2 1.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Orthopox_A5L PF06193.6 KOS13755.1 - 0.1 12.5 3.6 0.13 12.1 2.5 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Rootletin PF15035.1 KOS13755.1 - 0.11 12.5 8.5 0.13 12.2 0.2 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 KOS13755.1 - 0.16 11.6 8.4 0.24 11.0 5.9 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KOS13755.1 - 0.21 12.0 4.3 0.11 12.9 0.7 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) COMPASS-Shg1 PF05205.7 KOS13755.1 - 0.62 10.3 6.4 0.87 9.8 3.6 1.9 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4407 PF14362.1 KOS13755.1 - 1.3 7.9 4.6 1.5 7.7 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CR6_interact PF10147.4 KOS13756.1 - 0.00097 18.5 0.6 0.00097 18.5 0.4 1.8 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF533 PF04391.7 KOS13756.1 - 0.048 13.0 0.2 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) ACC_central PF08326.7 KOS13758.1 - 1.1e-169 565.8 0.0 1.4e-169 565.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KOS13758.1 - 2.5e-152 507.7 0.0 3.3e-152 507.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KOS13758.1 - 1.3e-50 171.6 0.0 2.5e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KOS13758.1 - 3e-24 85.2 0.0 9.2e-24 83.6 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KOS13758.1 - 1.5e-19 69.9 0.0 3.1e-18 65.7 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KOS13758.1 - 1.1e-13 50.5 0.0 2.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KOS13758.1 - 2.6e-13 50.1 0.0 9.1e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KOS13758.1 - 7e-07 28.8 0.0 3.1e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.1 KOS13758.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Dala_Dala_lig_C PF07478.8 KOS13758.1 - 0.0015 17.9 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KOS13758.1 - 0.0071 15.7 0.1 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KOS13758.1 - 0.066 12.3 0.5 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 HlyD family secretion protein DUF1014 PF06244.7 KOS13759.1 - 9.2e-25 87.2 8.2 3.6e-24 85.3 5.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) BNIP2 PF12496.3 KOS13759.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.6 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 U79_P34 PF03064.11 KOS13759.1 - 2.6 7.5 14.7 4.3 6.7 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 WD40 PF00400.27 KOS13760.1 - 1.6e-61 202.0 15.4 9.2e-12 44.3 0.0 8.7 9 0 0 9 9 9 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS13760.1 - 2.1e-06 27.6 0.0 0.032 13.9 0.0 3.8 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KOS13760.1 - 1.4e-05 24.6 0.3 3.3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 LisH Apc4_WD40 PF12894.2 KOS13760.1 - 7.8e-05 22.0 0.0 5.4 6.5 0.0 5.2 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 KOS13760.1 - 0.14 9.9 0.0 0.35 8.6 0.0 1.5 1 1 0 1 1 1 0 IKI3 family Ribosomal_S7 PF00177.16 KOS13761.1 - 1.6e-39 134.8 0.5 1.9e-39 134.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L17 PF01196.14 KOS13762.1 - 1.2e-30 105.9 0.3 4.4e-30 104.1 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein L17 Osmo_MPGsynth PF09488.5 KOS13762.1 - 0.075 11.6 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) CtaG_Cox11 PF04442.9 KOS13763.1 - 1.4e-54 183.9 0.0 1.8e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Inositol_P PF00459.20 KOS13764.1 - 5.2e-50 170.2 0.0 1.1e-49 169.2 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family QRPTase_C PF01729.14 KOS13764.1 - 2.5e-49 167.0 0.1 3.9e-49 166.4 0.1 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KOS13764.1 - 3.4e-21 74.8 0.0 1.3e-20 73.0 0.0 2.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Esterase PF00756.15 KOS13765.1 - 1.6e-44 152.2 0.1 1.8e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KOS13765.1 - 1.7e-06 27.8 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS13765.1 - 4.1e-05 22.9 0.0 6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KOS13765.1 - 0.013 15.1 0.1 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS13765.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Homeobox PF00046.24 KOS13765.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Homeobox domain Lipase_3 PF01764.20 KOS13765.1 - 0.081 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) NfrA_C PF13283.1 KOS13765.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term PGAP1 PF07819.8 KOS13765.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein zf-CHY PF05495.7 KOS13766.1 - 2.5e-15 56.3 16.2 2.5e-15 56.3 11.2 1.5 2 0 0 2 2 2 1 CHY zinc finger Cys_rich_KTR PF14205.1 KOS13766.1 - 0.0099 15.3 5.7 0.89 9.0 1.2 2.4 1 1 0 2 2 2 2 Cysteine-rich KTR zf-FPG_IleRS PF06827.9 KOS13766.1 - 0.018 14.6 0.5 0.018 14.6 0.4 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.1 KOS13766.1 - 0.038 13.4 7.5 0.22 11.0 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain LEA_5 PF00477.12 KOS13766.1 - 0.048 13.9 0.1 0.075 13.3 0.1 1.2 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Zn_Tnp_IS1595 PF12760.2 KOS13766.1 - 0.052 13.3 10.3 1.8 8.4 4.7 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DRP PF06044.7 KOS13766.1 - 0.11 11.4 2.7 0.19 10.6 0.3 1.9 1 1 1 2 2 2 0 Dam-replacing family Elf1 PF05129.8 KOS13766.1 - 0.62 9.8 9.0 2.7 7.7 5.4 2.3 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DZR PF12773.2 KOS13766.1 - 0.66 9.8 13.6 0.75 9.6 7.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 KOS13766.1 - 1.4 8.9 10.2 0.16 12.0 1.2 2.6 2 1 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 KOS13766.1 - 1.6 8.0 7.9 5 6.4 3.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 KOS13766.1 - 2 8.1 9.9 10 5.8 5.8 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Evr1_Alr PF04777.8 KOS13766.1 - 3.5 7.5 8.7 61 3.6 5.6 2.9 1 1 0 1 1 1 0 Erv1 / Alr family Zn-ribbon_8 PF09723.5 KOS13766.1 - 4 7.4 13.2 1.6 8.7 1.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.7 KOS13766.1 - 6.7 6.7 11.2 2.7 8.0 1.8 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DUF3797 PF12677.2 KOS13766.1 - 7.4 6.2 6.5 13 5.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Ribosomal_S8 PF00410.14 KOS13767.1 - 8.7e-25 87.0 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Formyl_trans_N PF00551.14 KOS13768.1 - 6.5e-22 77.9 0.0 7.5e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase tRNA-synt_His PF13393.1 KOS13769.1 - 1.2e-41 142.8 0.9 1.7e-36 125.8 0.0 2.5 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KOS13769.1 - 3.1e-18 65.9 0.0 5.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS13769.1 - 5.1e-10 39.1 0.0 9.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KOS13769.1 - 0.0043 15.8 1.2 0.32 9.7 0.3 2.8 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Amidohydro_1 PF01979.15 KOS13770.1 - 2.3e-56 191.8 2.8 3.6e-56 191.2 1.9 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KOS13770.1 - 1.1e-53 180.5 1.1 2.2e-53 179.4 0.8 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 KOS13770.1 - 1.4e-33 114.8 0.1 3.2e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 KOS13770.1 - 2e-26 91.7 0.0 4.7e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 KOS13770.1 - 4.1e-07 29.7 2.0 1.1e-06 28.3 1.4 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KOS13770.1 - 0.00044 19.5 0.7 0.006 15.8 0.1 2.6 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KOS13770.1 - 0.0017 18.4 0.2 0.3 11.0 0.1 2.6 2 0 0 2 2 2 1 Amidohydrolase Ras PF00071.17 KOS13771.1 - 9.6e-59 197.3 0.1 1.3e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS13771.1 - 5.5e-20 72.0 0.0 9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS13771.1 - 6.3e-16 58.1 0.1 7.7e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS13771.1 - 7e-07 28.8 0.0 4.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS13771.1 - 1.1e-05 24.7 0.1 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS13771.1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS13771.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KOS13771.1 - 0.021 14.3 0.1 0.061 12.8 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PEHE PF15275.1 KOS13772.1 - 1.9e-06 28.3 0.9 1.9e-06 28.3 0.7 2.5 3 0 0 3 3 3 1 PEHE domain SAS4 PF15460.1 KOS13772.1 - 9.7e-06 25.3 3.0 2.3e-05 24.1 2.1 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF781 PF05612.7 KOS13772.1 - 0.15 10.7 0.0 4.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Mouse protein of unknown function (DUF781) FAM176 PF14851.1 KOS13773.1 - 0.15 11.7 0.2 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 FAM176 family HD PF01966.17 KOS13774.1 - 0.00012 22.1 0.2 0.00017 21.5 0.1 1.5 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 KOS13774.1 - 0.004 16.4 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 HDOD domain HD_4 PF13328.1 KOS13774.1 - 0.0099 15.6 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 HD domain DUF706 PF05153.10 KOS13774.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) MFS_2 PF13347.1 KOS13775.1 - 3.3e-09 35.6 8.2 3.3e-09 35.6 5.7 3.3 2 1 0 3 3 3 1 MFS/sugar transport protein Borrelia_P13 PF05628.7 KOS13775.1 - 0.01 15.6 0.5 0.49 10.1 0.1 2.7 2 0 0 2 2 2 0 Borrelia membrane protein P13 NQR2_RnfD_RnfE PF03116.10 KOS13775.1 - 0.036 13.2 6.0 0.032 13.4 0.5 2.5 2 1 0 2 2 2 0 NQR2, RnfD, RnfE family MFS_1_like PF12832.2 KOS13775.1 - 0.37 10.6 6.2 0.37 10.6 0.0 3.2 3 0 0 3 3 3 0 MFS_1 like family SUR7 PF06687.7 KOS13775.1 - 5.2 6.5 10.3 1.2 8.6 0.1 3.3 3 1 1 4 4 4 0 SUR7/PalI family DUF1746 PF08508.5 KOS13776.1 - 0.00015 21.7 7.7 0.0013 18.6 5.3 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Abhydrolase_6 PF12697.2 KOS13777.1 - 4.7e-21 75.7 0.1 6.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS13777.1 - 5.7e-13 48.8 0.1 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS13777.1 - 9.2e-05 21.7 0.1 0.00048 19.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KOS13777.1 - 0.0001 22.0 0.8 0.00022 21.0 0.6 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KOS13777.1 - 0.00052 19.6 0.1 0.0059 16.1 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KOS13777.1 - 0.0046 16.4 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KOS13777.1 - 0.026 13.7 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_M16 PF00675.15 KOS13778.1 - 3.1e-39 134.1 0.0 4.9e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS13778.1 - 7.2e-38 130.1 0.0 1.2e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain SH3_1 PF00018.23 KOS13779.1 - 4.9e-44 147.4 1.2 7e-14 50.9 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 KOS13779.1 - 9e-42 140.4 4.1 1e-13 50.5 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KOS13779.1 - 8.3e-22 76.4 0.0 2.6e-07 30.0 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 KOS13779.1 - 3.8e-21 74.5 0.0 7.1e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_3 PF08239.6 KOS13779.1 - 2.1e-05 24.5 1.5 0.55 10.4 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 KOS13779.1 - 0.77 9.8 68.7 1.5 8.9 22.9 5.2 5 1 0 5 5 5 0 Domain of unknown function (DUF1720) Smr PF01713.16 KOS13780.1 - 2.9e-07 30.5 0.0 7.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KOS13780.1 - 6.6e-05 22.4 10.7 0.00089 18.8 0.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KOS13780.1 - 0.036 13.5 4.7 3.2 7.3 1.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain LIP PF03583.9 KOS13781.1 - 3.7e-48 164.2 0.0 4.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS13781.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2420 PF10336.4 KOS13782.1 - 1.2e-21 76.3 0.0 2.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) zf-C2HC5 PF06221.8 KOS13783.1 - 2.9e-11 42.9 4.6 4.7e-11 42.2 3.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type UCH_1 PF13423.1 KOS13784.1 - 7.4e-35 120.8 0.0 1.1e-34 120.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KOS13784.1 - 7.7e-20 71.8 0.0 3.2e-19 69.7 0.0 2.1 1 1 0 1 1 1 1 Exonuclease UCH PF00443.24 KOS13784.1 - 9.2e-05 21.6 0.0 0.00023 20.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KOS13784.1 - 0.0016 18.2 0.4 0.046 13.6 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat efThoc1 PF11957.3 KOS13785.1 - 7.6e-60 202.8 0.0 1.9e-59 201.4 0.0 1.6 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor WD40 PF00400.27 KOS13786.1 - 1e-10 41.0 0.1 0.099 12.5 0.0 6.3 6 1 0 6 6 6 3 WD domain, G-beta repeat SAP PF02037.22 KOS13788.1 - 4.9e-12 45.0 2.2 3.1e-11 42.4 0.7 2.2 2 0 0 2 2 2 1 SAP domain CIA30 PF08547.7 KOS13789.1 - 6.3e-22 78.1 0.0 2.7e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) AMP-binding PF00501.23 KOS13790.1 - 2.2e-69 233.8 0.1 2.6e-69 233.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS13790.1 - 2.7e-15 57.0 0.1 1e-14 55.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ham1p_like PF01725.11 KOS13791.1 - 3.6e-55 186.2 0.0 4.1e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Prefoldin_2 PF01920.15 KOS13792.1 - 1e-20 73.4 4.1 1.2e-20 73.1 2.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4164 PF13747.1 KOS13792.1 - 0.00099 19.1 8.0 0.19 11.8 1.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) DivIC PF04977.10 KOS13792.1 - 0.0088 15.5 4.8 0.48 9.9 0.2 2.2 1 1 1 2 2 2 2 Septum formation initiator XRCC4 PF06632.7 KOS13792.1 - 0.017 14.0 0.7 0.017 14.0 0.5 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF2730 PF10805.3 KOS13792.1 - 0.086 12.5 1.4 0.33 10.6 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ATG16 PF08614.6 KOS13792.1 - 0.11 12.3 6.7 0.88 9.3 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CBF_beta PF02312.12 KOS13792.1 - 0.2 11.2 3.7 0.093 12.3 0.3 1.8 1 1 0 2 2 2 0 Core binding factor beta subunit DUF4140 PF13600.1 KOS13792.1 - 0.22 11.9 3.6 3.2 8.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.3 KOS13792.1 - 0.26 11.0 5.8 0.46 10.2 0.1 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 KOS13792.1 - 0.45 8.8 2.3 0.53 8.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 KOS13792.1 - 0.51 10.1 4.5 0.7 9.7 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF848 PF05852.6 KOS13792.1 - 0.83 9.4 4.8 2.7 7.8 3.2 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_MLP1_2 PF07926.7 KOS13792.1 - 0.92 9.2 7.5 0.58 9.9 1.4 2.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PEP-utilisers_N PF05524.8 KOS13792.1 - 1.1 9.0 4.2 0.66 9.7 0.3 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Prefoldin PF02996.12 KOS13792.1 - 1.2 8.7 4.7 3.9 7.1 1.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.6 KOS13792.1 - 2.8 7.6 9.4 2.3e+02 1.4 6.4 2.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 IncA PF04156.9 KOS13792.1 - 4.2 6.9 11.9 29 4.2 8.3 1.9 1 1 0 1 1 1 0 IncA protein KfrA_N PF11740.3 KOS13792.1 - 5 7.6 10.4 25 5.3 7.2 1.9 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term YlqD PF11068.3 KOS13792.1 - 5 7.1 7.1 10 6.1 1.5 2.1 1 1 1 2 2 2 0 YlqD protein Pyridoxal_deC PF00282.14 KOS13793.1 - 7.3e-104 347.1 0.0 1e-103 346.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 KOS13793.1 - 0.00013 21.0 0.0 0.053 12.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II AAA_5 PF07728.9 KOS13794.1 - 2e-66 221.9 0.0 6.4e-28 97.2 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 KOS13794.1 - 0.00012 22.2 0.1 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 KOS13794.1 - 0.00087 18.9 0.0 1.4 8.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KOS13794.1 - 0.023 14.5 0.0 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Ribosomal_L28e PF01778.12 KOS13795.1 - 2.5e-28 98.8 0.4 2.5e-28 98.8 0.3 2.1 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KOS13795.1 - 1.4e-21 76.4 12.6 1.4e-21 76.4 8.7 3.3 1 1 2 3 3 3 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 KOS13795.1 - 0.039 13.3 0.5 0.07 12.5 0.4 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.7 KOS13795.1 - 0.34 8.7 25.5 0.44 8.4 17.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KOS13795.1 - 0.44 8.5 16.8 0.76 7.7 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein ProRS-C_1 PF09180.6 KOS13796.1 - 1.4e-25 89.0 0.2 2.7e-25 88.0 0.2 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KOS13796.1 - 5.9e-24 84.5 0.0 9.1e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS13796.1 - 9.2e-18 63.9 0.0 3.5e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 KOS13796.1 - 3.7e-12 46.1 0.7 6.7e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF155 PF02582.9 KOS13797.1 - 5.2e-51 173.0 0.0 9.7e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DnaJ PF00226.26 KOS13799.1 - 1.3e-17 63.2 0.2 1.3e-17 63.2 0.2 2.2 2 1 0 2 2 2 1 DnaJ domain AAA_23 PF13476.1 KOS13799.1 - 1.6 9.0 11.0 0.41 10.9 5.4 1.7 2 0 0 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.15 KOS13800.1 - 3.3e-35 121.1 1.5 5.2e-35 120.5 1.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KOS13800.1 - 3.6e-11 43.2 0.0 1.1e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 KOS13800.1 - 3.7e-10 39.3 1.3 8.9e-10 38.1 0.3 2.1 2 0 0 2 2 2 1 HRDC domain DUF883 PF05957.8 KOS13800.1 - 0.25 11.7 4.4 3.8 7.9 0.3 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Pyridoxal_deC PF00282.14 KOS13801.1 - 1.4e-61 208.0 0.0 2.1e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KOS13801.1 - 0.00046 19.0 0.0 0.0007 18.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS13801.1 - 0.081 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BolA PF01722.13 KOS13802.1 - 1.5e-13 50.4 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Nuf2 PF03800.9 KOS13803.1 - 4.5e-39 133.7 2.6 5.4e-39 133.4 0.1 2.3 2 1 0 2 2 2 1 Nuf2 family Glycohydro_20b2 PF14845.1 KOS13803.1 - 0.047 14.3 0.5 0.047 14.3 0.4 2.4 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like Reo_sigmaC PF04582.7 KOS13803.1 - 2.1 7.4 15.0 0.29 10.2 2.4 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Paf1 PF03985.8 KOS13804.1 - 1.4e-49 169.0 3.1 9.4e-38 130.0 0.0 2.3 2 0 0 2 2 2 2 Paf1 Cwf_Cwc_15 PF04889.7 KOS13804.1 - 2 8.0 19.1 4.4 6.9 6.1 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TPR_11 PF13414.1 KOS13805.1 - 1.3e-13 50.3 0.0 1.3e-13 50.3 0.0 3.4 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 KOS13805.1 - 9.3e-11 40.8 0.0 4.7e-05 22.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13805.1 - 8.3e-09 34.7 3.8 0.00013 21.5 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.26 KOS13805.1 - 1.5e-05 24.6 0.0 6.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 KOS13805.1 - 0.00013 21.5 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 KOS13805.1 - 0.00026 20.8 0.3 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13805.1 - 0.0056 16.3 0.0 0.076 12.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13805.1 - 0.0078 15.9 0.3 0.053 13.3 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KOS13805.1 - 0.032 14.1 0.3 0.099 12.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13805.1 - 0.04 14.6 0.0 0.04 14.6 0.0 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13805.1 - 6.5 7.6 12.1 0.32 11.7 0.2 4.8 4 1 2 6 6 6 0 Tetratricopeptide repeat Actin PF00022.14 KOS13806.1 - 3.9e-18 65.0 0.0 3.1e-08 32.4 0.0 3.0 3 0 0 3 3 3 3 Actin DUF1713 PF08213.6 KOS13807.1 - 4.6e-13 48.5 23.9 4.6e-13 48.5 16.6 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Abhydrolase_6 PF12697.2 KOS13808.1 - 7.7e-15 55.3 1.3 1.1e-14 54.8 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS13808.1 - 9.6e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS13808.1 - 1.6e-12 47.1 0.0 6.1e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KOS13808.1 - 4.5e-05 22.7 2.7 0.034 13.3 0.0 3.2 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KOS13808.1 - 9.6e-05 22.0 0.0 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KOS13808.1 - 0.00095 18.7 0.5 0.14 11.7 0.3 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS13808.1 - 0.0095 15.3 0.0 1.3 8.4 0.0 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase LCAT PF02450.10 KOS13808.1 - 0.037 13.0 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.2 KOS13808.1 - 0.046 12.6 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.7 KOS13808.1 - 0.14 11.4 0.3 1.7 7.8 0.2 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DNA_pol_B_2 PF03175.8 KOS13809.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral CYSTM PF12734.2 KOS13811.1 - 4.2e-05 23.5 21.1 4.2e-05 23.5 14.6 3.8 2 2 1 3 3 3 2 Cysteine-rich TM module stress tolerance AAA_33 PF13671.1 KOS13812.1 - 9.6e-17 61.1 1.3 7e-16 58.4 0.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS13812.1 - 0.00048 20.9 0.1 0.00081 20.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 KOS13812.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain CPT PF07931.7 KOS13812.1 - 0.0011 18.5 0.1 0.0084 15.7 0.0 1.9 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KOS13812.1 - 0.0031 17.7 4.1 0.37 11.0 2.8 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS13812.1 - 0.0079 15.3 0.0 0.04 12.9 0.0 1.7 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KOS13812.1 - 0.0082 16.1 0.1 0.013 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KOS13812.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CoaE PF01121.15 KOS13812.1 - 0.026 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_22 PF13401.1 KOS13812.1 - 0.03 14.4 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS13812.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 KOS13812.1 - 0.091 12.4 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.7 KOS13812.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SKI PF01202.17 KOS13812.1 - 0.18 11.6 0.5 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KOS13812.1 - 0.18 10.9 0.2 0.46 9.6 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ACBP PF00887.14 KOS13813.1 - 2.1e-31 107.4 0.1 2.1e-31 107.4 0.1 1.3 2 0 0 2 2 2 1 Acyl CoA binding protein 3Beta_HSD PF01073.14 KOS13814.1 - 1.6e-54 184.5 0.0 6.2e-51 172.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KOS13814.1 - 2.7e-29 102.2 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KOS13814.1 - 1.9e-11 43.3 0.7 1.9e-09 36.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KOS13814.1 - 1.8e-10 41.0 0.1 1.1e-09 38.5 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KOS13814.1 - 5.7e-09 35.2 0.1 8.6e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KOS13814.1 - 7.3e-05 22.7 0.1 0.00016 21.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 KOS13814.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KOS13814.1 - 0.02 14.5 0.7 0.083 12.5 0.5 1.9 1 1 0 1 1 1 0 KR domain DnaJ PF00226.26 KOS13815.1 - 2.5e-17 62.3 0.1 4.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PhrC_PhrF PF11131.3 KOS13815.1 - 0.034 13.7 0.3 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF95 PF01944.12 KOS13815.1 - 0.054 13.1 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF95 WD40 PF00400.27 KOS13816.1 - 1.7e-22 78.4 7.6 4.2e-06 26.4 0.0 5.9 5 1 1 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KOS13816.1 - 5.7e-06 26.1 0.3 3.8e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KOS13816.1 - 0.00012 20.0 0.2 0.011 13.6 0.2 2.3 2 0 0 2 2 2 2 IKI3 family TFIIIC_delta PF12657.2 KOS13816.1 - 0.001 18.8 0.4 1.6 8.3 0.1 2.9 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Glycos_transf_4 PF00953.16 KOS13817.1 - 3.6e-29 101.6 9.2 3.6e-29 101.6 6.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 4 Pkinase PF00069.20 KOS13818.1 - 6.2e-74 248.4 0.0 7.2e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13818.1 - 1.3e-35 122.7 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13818.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS13818.1 - 0.024 14.3 0.1 0.083 12.6 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KOS13818.1 - 0.038 13.0 0.2 0.085 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS13818.1 - 0.04 12.7 0.0 0.088 11.6 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF1751 PF08551.5 KOS13819.1 - 3.3e-21 75.4 4.3 8e-21 74.2 3.0 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Methyltransf_23 PF13489.1 KOS13820.1 - 6.4e-15 55.2 0.0 3.5e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KOS13820.1 - 9.9e-11 41.9 0.0 4.5e-10 39.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS13820.1 - 8.6e-08 32.4 0.0 1.9e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS13820.1 - 1.6e-07 31.6 0.0 7.3e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS13820.1 - 2.2e-06 27.3 0.0 7.1e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS13820.1 - 2.6e-06 27.9 0.0 5.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS13820.1 - 0.00026 20.9 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KOS13820.1 - 0.024 13.5 0.0 0.085 11.8 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family MTS PF05175.9 KOS13820.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF500 PF04366.7 KOS13821.1 - 1.4e-36 124.6 0.0 2.2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Med1 PF10744.4 KOS13822.1 - 0.00031 19.6 0.1 0.0022 16.8 0.0 2.1 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Cellulase PF00150.13 KOS13823.1 - 2.6e-12 46.5 10.3 4.4e-12 45.8 7.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.13 KOS13824.1 - 2.9e-23 81.8 1.2 6.5e-06 26.2 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 KOS13824.1 - 4.7e-08 33.0 1.4 3.5e-05 23.9 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS13824.1 - 3e-06 27.5 0.3 8.5e-06 26.1 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS13824.1 - 1e-05 25.7 0.0 3.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KOS13824.1 - 1.6e-05 24.6 0.3 0.041 14.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat BTB PF00651.26 KOS13824.1 - 5.9e-05 23.0 0.0 2 8.4 0.0 3.7 2 2 1 3 3 3 2 BTB/POZ domain Ank PF00023.25 KOS13824.1 - 0.00074 19.2 0.7 0.034 13.9 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat PQQ_3 PF13570.1 KOS13824.1 - 0.18 12.1 1.9 8.3 6.8 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain Mvb12 PF09452.5 KOS13824.1 - 0.2 11.8 4.0 0.6 10.3 2.8 1.8 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 RCC1_2 PF13540.1 KOS13824.1 - 1.3 8.7 21.9 2.1 8.0 0.0 5.9 6 0 0 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat DAGK_cat PF00781.19 KOS13826.1 - 4.7e-22 77.8 0.1 7.7e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 KOS13826.1 - 0.00064 18.5 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Whirly PF08536.6 KOS13826.1 - 0.16 11.4 0.1 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Whirly transcription factor DEAD PF00270.24 KOS13827.1 - 7.1e-28 97.2 0.0 1.4e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13827.1 - 2.5e-06 27.2 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS13827.1 - 0.00024 21.0 0.0 0.00046 20.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS13827.1 - 0.00025 21.1 0.1 0.013 15.6 0.0 3.3 2 2 0 2 2 2 1 AAA domain SNF2_N PF00176.18 KOS13827.1 - 0.00096 18.0 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_16 PF13191.1 KOS13827.1 - 0.007 16.3 1.1 0.1 12.6 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain VWA_3 PF13768.1 KOS13827.1 - 0.018 14.7 0.1 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Myosin_head PF00063.16 KOS13827.1 - 0.11 10.5 0.0 0.23 9.4 0.0 1.4 2 0 0 2 2 2 0 Myosin head (motor domain) mRNA_cap_enzyme PF01331.14 KOS13828.1 - 1.2e-46 158.8 0.0 1.6e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KOS13828.1 - 2e-16 60.2 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KOS13828.1 - 2.7e-06 26.8 0.0 8.5e-05 22.0 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Polysacc_deac_1 PF01522.16 KOS13829.1 - 4.1e-30 103.9 0.0 6.9e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase zf-H2C2_2 PF13465.1 KOS13830.1 - 0.0093 16.2 0.9 0.0093 16.2 0.6 2.7 3 0 0 3 3 3 1 Zinc-finger double domain LEA_2 PF03168.8 KOS13831.1 - 4.2e-05 23.8 0.2 7.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein Herpes_UL45 PF05473.7 KOS13831.1 - 0.059 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 UL45 protein DUF1358 PF07096.6 KOS13832.1 - 0.0055 16.3 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1358) TMEM51 PF15345.1 KOS13832.1 - 0.081 12.6 0.2 0.24 11.0 0.0 1.9 1 1 1 2 2 2 0 Transmembrane protein 51 Ribophorin_II PF05817.9 KOS13833.1 - 0.0014 16.9 0.1 0.0017 16.6 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Utp12 PF04003.7 KOS13834.1 - 1.2e-12 47.7 0.1 2.4e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KOS13834.1 - 0.0047 16.7 0.8 0.026 14.3 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Zn_clus PF00172.13 KOS13835.1 - 2.7e-06 27.1 7.7 6.2e-06 26.0 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.15 KOS13836.1 - 3.8e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Ank_2 PF12796.2 KOS13837.1 - 9.6e-08 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS13837.1 - 1.2e-06 28.8 0.0 3.6e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS13837.1 - 4.2e-06 26.4 0.0 0.00026 20.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.1 KOS13837.1 - 5.7e-06 26.1 10.0 5.7e-06 26.1 6.9 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Ank_5 PF13857.1 KOS13837.1 - 1.8e-05 24.8 0.0 7e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KOS13837.1 - 2.1e-05 24.1 0.0 0.00018 21.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.19 KOS13837.1 - 0.00016 21.3 14.3 0.028 14.1 3.8 2.6 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cut8_C PF08559.5 KOS13838.1 - 1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle WD40 PF00400.27 KOS13839.1 - 1e-17 63.2 18.7 5.3e-06 26.1 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat PPR_2 PF13041.1 KOS13840.1 - 1.7e-09 37.4 0.0 0.00019 21.3 0.0 3.2 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KOS13840.1 - 2.3e-06 27.4 5.1 0.0031 17.6 0.0 5.4 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 KOS13840.1 - 0.00043 20.0 0.0 0.11 12.5 0.0 3.7 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 KOS13840.1 - 0.072 12.5 0.0 1.2 8.6 0.0 2.7 2 0 0 2 2 2 0 PPR repeat Asp_Glu_race PF01177.17 KOS13841.1 - 3.8e-26 92.3 0.4 4.6e-26 92.0 0.3 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aminotran_4 PF01063.14 KOS13842.1 - 7.6e-13 48.4 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Oxidored_FMN PF00724.15 KOS13843.1 - 5.6e-48 163.6 0.0 1.7e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HA2 PF04408.18 KOS13844.1 - 2.5e-27 94.8 0.0 1.2e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS13844.1 - 1.5e-23 82.7 0.0 4.9e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS13844.1 - 1.9e-12 46.8 0.0 4.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS13844.1 - 3.1e-07 30.0 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS13844.1 - 1.4e-05 25.2 0.1 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KOS13844.1 - 0.00075 18.4 0.1 0.0028 16.5 0.0 1.9 3 0 0 3 3 3 1 Type II/IV secretion system protein NACHT PF05729.7 KOS13844.1 - 0.0064 16.1 0.2 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Sigma54_activ_2 PF14532.1 KOS13844.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain ResIII PF04851.10 KOS13844.1 - 0.016 15.0 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KOS13844.1 - 0.02 14.8 0.1 0.19 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KOS13844.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KOS13844.1 - 0.029 14.0 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 KOS13844.1 - 0.03 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KOS13844.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KOS13844.1 - 0.048 13.9 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KOS13844.1 - 0.075 12.4 0.0 8.5 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 KOS13844.1 - 0.075 12.2 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 KOS13844.1 - 0.077 11.8 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Myosin_head PF00063.16 KOS13844.1 - 0.08 10.9 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_29 PF13555.1 KOS13844.1 - 0.091 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 KOS13845.1 - 1.7e-42 144.7 0.0 3.1e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13845.1 - 3e-25 87.8 0.0 6.1e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KOS13845.1 - 7.7e-06 24.9 0.0 1.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KOS13845.1 - 0.00033 20.5 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Hint_2 PF13403.1 KOS13845.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Hint domain ATPase-cat_bd PF12156.3 KOS13845.1 - 0.16 12.4 0.6 2.8 8.5 0.0 3.1 4 0 0 4 4 4 0 Putative metal-binding domain of cation transport ATPase Spore_coat_CotO PF14153.1 KOS13845.1 - 0.88 8.9 5.1 1.4 8.3 3.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.1 KOS13845.1 - 1.1 8.1 5.5 1.6 7.6 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGK PF00162.14 KOS13846.1 - 4.1e-151 502.9 1.7 4.6e-151 502.7 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Tim17 PF02466.14 KOS13847.1 - 7.3e-27 93.9 4.2 9.3e-27 93.6 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 KOS13848.1 - 2e-08 33.7 0.0 5.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13848.1 - 1.4e-06 27.9 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13848.1 - 7e-06 25.9 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS13848.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KOS13848.1 - 0.082 12.6 3.6 0.14 11.8 2.5 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IncA PF04156.9 KOS13848.1 - 8.7 5.8 6.5 14 5.2 4.5 1.3 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 KOS13850.1 - 0.00012 20.9 3.2 0.00012 20.9 2.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS13850.1 - 0.00017 20.3 5.6 0.00021 20.0 3.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Nuc_H_symport PF03825.11 KOS13850.1 - 0.015 14.0 0.2 0.02 13.6 0.2 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter 6PGD PF00393.14 KOS13851.1 - 1.3e-132 441.3 0.0 1.7e-132 441.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KOS13851.1 - 8.5e-52 175.2 0.0 1.3e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KOS13851.1 - 0.0076 16.6 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KOS13851.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KOS13851.1 - 0.024 13.7 0.1 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Seipin PF06775.9 KOS13852.1 - 9.6e-30 103.5 0.0 1.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) bZIP_2 PF07716.10 KOS13854.1 - 3.8e-11 42.6 14.1 7.7e-11 41.6 9.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KOS13854.1 - 7.6e-05 22.5 13.3 0.00016 21.5 9.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KOS13854.1 - 0.0026 18.0 7.4 0.0058 16.8 5.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Rab5-bind PF09311.6 KOS13854.1 - 0.0029 17.5 1.2 0.0029 17.5 0.8 1.8 2 0 0 2 2 2 1 Rabaptin-like protein HALZ PF02183.13 KOS13854.1 - 0.02 14.6 0.2 0.036 13.7 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phlebovirus_NSM PF07246.6 KOS13854.1 - 0.034 13.3 1.8 0.057 12.5 1.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2205 PF10224.4 KOS13854.1 - 0.039 13.5 0.6 0.11 12.1 0.4 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) TSC22 PF01166.13 KOS13854.1 - 0.039 13.9 0.2 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 KOS13854.1 - 0.16 12.3 2.0 0.34 11.2 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CASP_C PF08172.7 KOS13854.1 - 0.17 10.8 5.1 0.37 9.7 3.5 1.5 1 0 0 1 1 1 0 CASP C terminal DivIC PF04977.10 KOS13854.1 - 0.18 11.3 1.8 0.4 10.1 1.3 1.6 1 0 0 1 1 1 0 Septum formation initiator IFT20 PF14931.1 KOS13854.1 - 0.22 11.4 4.1 0.44 10.4 2.8 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Spore_III_AF PF09581.5 KOS13854.1 - 0.51 10.1 2.5 1 9.1 1.7 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2315 PF10231.4 KOS13855.1 - 1.5e-06 28.0 3.7 2.2e-06 27.5 2.6 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) TIR_2 PF13676.1 KOS13855.1 - 0.042 13.9 0.3 0.058 13.5 0.2 1.2 1 0 0 1 1 1 0 TIR domain Uso1_p115_head PF04869.9 KOS13855.1 - 0.072 11.8 0.1 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region C2 PF00168.25 KOS13857.1 - 4.3e-07 29.6 0.1 6.7e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 KOS13857.1 - 0.00092 19.6 0.6 0.0026 18.2 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain RNA_pol_3_Rpc31 PF11705.3 KOS13859.1 - 2e-12 47.5 23.2 2.2e-12 47.4 16.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SURF2 PF05477.6 KOS13859.1 - 0.13 11.3 5.8 0.13 11.3 4.0 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TPR_11 PF13414.1 KOS13860.1 - 1.3e-25 88.8 52.1 3.4e-10 39.4 1.2 12.9 7 4 9 16 16 16 8 TPR repeat TPR_1 PF00515.23 KOS13860.1 - 1.2e-24 84.8 8.9 0.00031 20.2 0.0 11.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS13860.1 - 2.5e-24 83.1 39.1 0.00037 20.1 0.1 15.8 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_8 PF13181.1 KOS13860.1 - 5.6e-23 78.9 0.7 0.00072 19.1 0.0 11.4 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13860.1 - 8.2e-16 58.1 55.1 4.5e-05 23.7 0.7 11.7 6 4 5 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13860.1 - 2.2e-15 56.3 66.0 9.3e-10 38.3 0.6 14.1 9 4 8 17 17 17 7 Tetratricopeptide repeat TPR_17 PF13431.1 KOS13860.1 - 1.3e-12 46.8 25.1 0.0047 17.0 0.0 13.1 16 1 1 17 17 15 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13860.1 - 3.1e-12 46.8 101.1 1.4e-06 28.7 2.4 15.0 12 3 5 17 17 15 8 Tetratricopeptide repeat TPR_7 PF13176.1 KOS13860.1 - 8.8e-12 43.8 29.0 0.00014 21.3 0.1 11.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13860.1 - 2.2e-11 43.3 84.9 0.013 16.0 0.7 17.2 12 6 7 19 19 18 6 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13860.1 - 5.5e-09 35.9 36.2 0.0083 16.5 0.2 13.3 14 0 0 14 14 11 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS13860.1 - 0.023 14.5 6.4 0.33 10.8 0.3 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 KOS13860.1 - 0.028 14.8 0.5 0.028 14.8 0.3 14.3 15 0 0 15 15 10 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS13860.1 - 0.34 10.7 49.7 0.067 13.0 0.9 9.4 8 2 2 10 10 10 0 Tetratricopeptide repeat ChAPs PF09295.5 KOS13860.1 - 0.92 8.1 3.6 20 3.7 0.0 4.0 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3414 PF11894.3 KOS13861.1 - 2.7e-225 750.6 0.0 3.7e-225 750.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Suf PF05843.9 KOS13862.1 - 4.3e-70 236.6 7.7 6.8e-69 232.6 0.0 4.3 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) PRELI PF04707.9 KOS13862.1 - 8e-24 83.9 0.0 1.9e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 PRELI-like family TPR_19 PF14559.1 KOS13862.1 - 0.00021 21.5 3.0 0.032 14.5 0.4 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13862.1 - 0.0012 19.3 7.1 0.79 10.5 0.9 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS13862.1 - 0.0074 16.6 0.8 8.6 7.0 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat IBN_N PF03810.14 KOS13863.1 - 4e-05 23.4 0.0 0.00027 20.7 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain RINGv PF12906.2 KOS13864.1 - 1.7e-14 53.5 12.7 2.9e-14 52.8 8.8 1.4 1 0 0 1 1 1 1 RING-variant domain SIMPL PF04402.9 KOS13864.1 - 0.057 13.2 1.1 0.093 12.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) zf-RING_2 PF13639.1 KOS13864.1 - 3.1 7.7 11.9 5.9 6.8 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain GTP_EFTU PF00009.22 KOS13865.1 - 6.5e-62 208.3 0.1 9.6e-62 207.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KOS13865.1 - 8.4e-38 128.6 0.0 2e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KOS13865.1 - 3.4e-21 74.9 0.0 7e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KOS13865.1 - 9.8e-13 47.7 0.0 2.3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KOS13865.1 - 1.8e-10 40.7 0.0 1.8e-09 37.5 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS13865.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase gp12-short_mid PF09089.5 KOS13865.1 - 0.14 12.0 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain TruB_N PF01509.13 KOS13866.1 - 1.3e-39 135.7 0.0 1.7e-38 132.1 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 KOS13867.1 - 8.1e-29 99.3 0.1 4e-28 97.1 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KOS13867.1 - 4.2e-23 82.1 7.7 3.8e-22 79.0 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KOS13867.1 - 2.9e-20 71.7 0.9 6.7e-20 70.6 0.6 1.7 1 0 0 1 1 1 1 PUA domain CDC45 PF02724.9 KOS13867.1 - 4.9 5.0 28.2 6.3 4.7 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CT47 PF15623.1 KOS13867.1 - 5.2 6.7 26.1 7.9 6.1 18.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 RNase_H2-Ydr279 PF09468.5 KOS13867.1 - 5.5 6.0 22.2 8.6 5.4 15.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SDA1 PF05285.7 KOS13867.1 - 9 5.4 38.7 12 5.0 26.8 1.2 1 0 0 1 1 1 0 SDA1 MTHFR PF02219.12 KOS13868.1 - 4e-108 360.8 0.0 5.9e-108 360.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_60s PF00428.14 KOS13869.1 - 1.5e-29 102.1 9.4 1.8e-29 101.9 6.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein tRNA-synt_2b PF00587.20 KOS13870.1 - 5.4e-35 120.5 0.3 9.8e-35 119.6 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KOS13870.1 - 1.3e-21 76.6 7.0 1.3e-21 76.6 4.8 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CR6_interact PF10147.4 KOS13870.1 - 0.0056 16.0 6.2 0.0089 15.3 4.3 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3749 PF12568.3 KOS13870.1 - 0.034 13.7 0.1 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4200 PF13863.1 KOS13870.1 - 0.58 10.1 11.4 0.21 11.5 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.9 KOS13870.1 - 5 7.0 12.5 0.34 10.8 5.2 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KOS13870.1 - 5.5 6.5 5.8 0.9 9.1 1.4 1.6 2 0 0 2 2 2 0 IncA protein Sugar_tr PF00083.19 KOS13871.1 - 2.2e-27 95.7 30.3 4e-20 71.8 8.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS13871.1 - 9.3e-24 83.7 50.5 8.3e-19 67.5 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KOS13871.1 - 2.3e-05 23.0 21.9 0.0042 15.5 1.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein RhoGEF PF00621.15 KOS13872.1 - 1.2e-12 48.0 0.4 1.2e-11 44.7 0.2 2.3 1 1 0 1 1 1 1 RhoGEF domain Ndufs5 PF10200.4 KOS13872.1 - 0.0035 17.2 0.6 0.0076 16.2 0.4 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KOS13872.1 - 0.012 15.7 0.9 0.032 14.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Cmc1 PF08583.5 KOS13872.1 - 0.22 11.3 1.7 0.48 10.2 1.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Vps54 PF07928.7 KOS13873.1 - 6.1e-48 162.3 0.2 1.8e-47 160.8 0.1 1.9 1 0 0 1 1 1 1 Vps54-like protein zf-C3HC4_2 PF13923.1 KOS13874.1 - 2.7e-10 40.0 7.2 5e-10 39.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS13874.1 - 2.9e-09 36.6 6.6 5.3e-09 35.7 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KOS13874.1 - 7.2e-09 35.1 5.0 1.3e-08 34.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS13874.1 - 2.3e-07 30.3 4.1 4.3e-07 29.4 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS13874.1 - 9.8e-07 28.4 5.2 2e-06 27.4 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KOS13874.1 - 3.3e-05 23.5 2.0 3.5e-05 23.4 0.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KOS13874.1 - 0.0002 21.1 8.2 0.0023 17.7 6.1 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KOS13874.1 - 0.00047 19.6 2.0 0.00095 18.6 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 KOS13874.1 - 0.0038 17.1 1.2 0.009 15.8 0.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-rbx1 PF12678.2 KOS13874.1 - 0.19 11.8 3.1 0.67 10.1 2.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 KOS13874.1 - 3.2 7.3 8.0 9 5.8 5.5 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Atg14 PF10186.4 KOS13875.1 - 1.2e-07 30.9 0.1 1.8e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF367 PF04034.8 KOS13877.1 - 1.1e-43 147.8 0.0 1.4e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KOS13877.1 - 1.4e-13 50.1 0.2 2.2e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2890 PF11081.3 KOS13877.1 - 0.022 14.8 1.6 0.032 14.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF572 PF04502.8 KOS13877.1 - 0.048 12.8 2.1 0.077 12.2 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Daxx PF03344.10 KOS13877.1 - 0.11 10.9 4.4 0.15 10.5 3.1 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 KOS13877.1 - 0.22 9.6 6.3 0.32 9.1 4.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sigma70_ner PF04546.8 KOS13877.1 - 1.1 8.8 7.4 2.2 7.8 5.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RR_TM4-6 PF06459.7 KOS13877.1 - 1.4 8.7 6.1 2 8.2 3.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 KOS13877.1 - 3.7 5.3 11.0 5.5 4.7 7.6 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 KOS13877.1 - 4.3 7.2 7.6 6.6 6.6 5.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Mpp10 PF04006.7 KOS13877.1 - 4.8 5.4 13.0 6.6 4.9 9.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Ribosomal_L22e PF01776.12 KOS13878.1 - 8.5e-45 151.3 0.1 1.1e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Acyltransferase PF01553.16 KOS13879.1 - 7e-18 64.3 0.0 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Ribosomal_S28e PF01200.13 KOS13880.1 - 9.8e-33 111.7 1.7 9.9e-33 111.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF883 PF05957.8 KOS13881.1 - 0.0032 17.8 5.6 0.11 12.8 2.4 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 KOS13881.1 - 0.0074 16.1 9.2 0.45 10.4 0.2 2.1 1 1 1 2 2 2 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Apolipoprotein PF01442.13 KOS13881.1 - 0.0077 15.7 1.5 0.01 15.3 1.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HR1 PF02185.11 KOS13881.1 - 0.015 15.0 1.6 0.021 14.5 1.1 1.2 1 0 0 1 1 1 0 Hr1 repeat ALIX_LYPXL_bnd PF13949.1 KOS13881.1 - 0.036 13.0 2.7 0.039 12.9 1.9 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV WEMBL PF05701.6 KOS13881.1 - 0.04 12.3 3.4 0.05 12.0 2.4 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light YtxH PF12732.2 KOS13881.1 - 0.042 14.2 7.3 6.1 7.2 5.1 2.2 1 1 0 1 1 1 0 YtxH-like protein MT0933_antitox PF14013.1 KOS13881.1 - 0.093 12.8 5.8 0.13 12.4 2.8 2.2 1 1 1 2 2 2 0 MT0933-like antitoxin protein Apo-CIII PF05778.7 KOS13881.1 - 0.13 11.6 5.3 0.56 9.6 0.9 2.3 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Fib_alpha PF08702.5 KOS13881.1 - 0.29 11.2 2.1 0.33 11.0 1.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HrpE PF06188.7 KOS13881.1 - 0.31 10.7 4.1 0.37 10.4 2.8 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Pex19 PF04614.7 KOS13881.1 - 0.37 10.3 6.9 0.42 10.1 4.8 1.0 1 0 0 1 1 1 0 Pex19 protein family DUF3450 PF11932.3 KOS13881.1 - 0.5 9.5 7.1 0.54 9.4 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATP-synt_B PF00430.13 KOS13881.1 - 0.58 9.9 9.3 1.3 8.8 6.4 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4398 PF14346.1 KOS13881.1 - 0.9 9.6 11.6 2.2 8.4 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) KfrA_N PF11740.3 KOS13881.1 - 0.97 9.8 8.2 0.9 9.9 3.7 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term PPE PF00823.14 KOS13881.1 - 1.7 8.4 6.6 1.6 8.5 3.1 1.7 1 1 1 2 2 2 0 PPE family LEA_4 PF02987.11 KOS13881.1 - 3.5 7.5 8.3 0.64 9.9 0.2 2.9 3 1 0 3 3 3 0 Late embryogenesis abundant protein DUF4407 PF14362.1 KOS13881.1 - 8.9 5.1 7.0 10 5.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF2A PF08662.6 KOS13882.1 - 9.2e-41 139.6 0.5 8.9e-37 126.6 0.1 4.2 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KOS13882.1 - 0.0078 15.8 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTP_synth_N PF06418.9 KOS13883.1 - 7.3e-116 386.0 0.0 1e-115 385.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KOS13883.1 - 1.1e-49 168.4 0.0 1.7e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KOS13883.1 - 8.7e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KOS13883.1 - 0.0042 16.5 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Carn_acyltransf PF00755.15 KOS13884.1 - 5e-158 526.8 0.0 5.7e-158 526.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SF3b10 PF07189.6 KOS13885.1 - 1.2e-25 89.1 0.0 1.9e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Steroid_dh PF02544.11 KOS13885.1 - 0.066 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase MutS_V PF00488.16 KOS13886.1 - 1.6e-73 247.0 0.1 2.5e-73 246.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS13886.1 - 1.5e-29 103.2 2.2 1.5e-29 103.2 1.5 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KOS13886.1 - 2.7e-22 78.9 0.1 5.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KOS13886.1 - 3.1e-07 30.5 0.1 7.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KOS13886.1 - 0.00033 20.7 0.0 0.00089 19.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KOS13886.1 - 0.33 10.5 1.9 0.43 10.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain adh_short PF00106.20 KOS13887.1 - 2e-10 40.8 0.0 2.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS13887.1 - 2.9e-07 30.4 0.0 3.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KOS13887.1 - 0.00098 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KOS13887.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 1 1 2 2 2 0 KR domain Ribosomal_L32p PF01783.18 KOS13889.1 - 1.4e-14 53.9 2.6 2e-14 53.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Sgf11 PF08209.6 KOS13889.1 - 0.71 9.2 4.6 1.4 8.2 0.1 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 KOS13890.1 - 1e-05 25.5 2.5 1e-05 25.5 1.7 2.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KOS13890.1 - 1.9e-05 24.7 19.7 3.1e-05 24.0 1.7 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KOS13890.1 - 0.015 15.4 0.4 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS13890.1 - 0.13 12.5 1.8 0.34 11.1 1.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KOS13890.1 - 0.18 11.7 2.6 0.19 11.6 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KOS13890.1 - 0.71 10.3 15.2 0.096 13.0 0.6 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Tubulin PF00091.20 KOS13891.1 - 4.3e-67 226.1 0.0 6.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS13891.1 - 5.9e-41 139.4 0.0 9.4e-41 138.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS13891.1 - 0.00021 21.3 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain ParA PF10609.4 KOS13892.1 - 8.4e-30 102.4 0.1 1.9e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KOS13892.1 - 1.7e-15 56.9 0.2 4.3e-15 55.6 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KOS13892.1 - 3.6e-07 30.2 0.1 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS13892.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KOS13892.1 - 0.0023 17.0 1.8 0.0023 17.0 1.2 1.8 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 KOS13892.1 - 0.0057 15.7 0.2 0.01 14.9 0.0 1.4 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.13 KOS13892.1 - 0.019 14.1 0.2 0.061 12.5 0.2 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KOS13892.1 - 0.025 14.1 0.4 0.79 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpb6 PF01192.17 KOS13893.1 - 4e-22 77.6 0.2 5.7e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 FAD_binding_2 PF00890.19 KOS13894.1 - 2.2e-125 418.8 3.8 2.9e-125 418.3 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KOS13894.1 - 3.3e-48 162.7 1.6 4.9e-48 162.2 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 KOS13894.1 - 2.2e-05 23.6 0.5 0.0084 15.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KOS13894.1 - 3.2e-05 22.9 1.5 0.036 12.9 1.8 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KOS13894.1 - 0.0002 20.3 0.3 0.0045 15.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS13894.1 - 0.00079 19.3 4.2 0.0038 17.1 0.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS13894.1 - 0.019 15.0 0.9 4.6 7.2 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS13894.1 - 0.022 13.8 1.3 0.032 13.2 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KOS13894.1 - 0.36 9.2 4.5 0.56 8.6 0.7 2.7 3 0 0 3 3 3 0 HI0933-like protein ICL PF00463.16 KOS13895.1 - 2.1e-259 861.1 3.8 2.3e-259 860.9 2.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KOS13895.1 - 8.2e-10 38.3 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KOS13895.1 - 0.046 13.1 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain ADH_zinc_N PF00107.21 KOS13896.1 - 2.3e-19 69.2 0.2 3.8e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS13896.1 - 1.4e-12 48.5 0.1 1.5e-11 45.2 0.0 2.2 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS13896.1 - 0.0018 18.0 0.0 0.069 12.9 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 KOS13896.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal UQ_con PF00179.21 KOS13897.1 - 9.2e-52 174.1 0.0 1.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS13897.1 - 2e-05 24.3 0.0 2.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KOS13897.1 - 0.00093 19.0 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KOS13897.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prenyltrans PF00432.16 KOS13898.1 - 2.1e-50 167.9 15.6 7.5e-11 41.4 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS13898.1 - 9.9e-45 151.5 1.8 9.2e-14 51.8 0.0 4.0 1 1 5 6 6 6 6 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS13898.1 - 4.4e-09 36.3 0.1 4e-06 26.7 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like PEX11 PF05648.9 KOS13899.1 - 2e-64 216.9 1.5 2.3e-64 216.7 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pkinase PF00069.20 KOS13900.1 - 1.8e-54 184.5 0.0 2.6e-54 184.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS13900.1 - 1.8e-22 79.6 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS13900.1 - 0.0033 16.4 0.0 0.0073 15.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS13900.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF2_N PF00176.18 KOS13902.1 - 1.1e-70 237.8 1.7 2.4e-70 236.7 1.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KOS13902.1 - 3e-53 179.6 17.0 3e-53 179.6 11.8 2.7 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 KOS13902.1 - 1.1e-12 47.5 0.0 2.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS13902.1 - 1.4e-05 25.0 0.0 5.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CPSF_A PF03178.10 KOS13903.1 - 3.1e-83 279.5 0.0 4.3e-82 275.7 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KOS13903.1 - 7.1e-67 225.6 0.0 1e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1945 PF09178.5 KOS13903.1 - 0.1 12.4 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) CathepsinC_exc PF08773.6 KOS13903.1 - 0.23 11.6 0.0 0.53 10.4 0.0 1.6 1 0 0 1 1 1 0 Cathepsin C exclusion domain tRNA-synt_2 PF00152.15 KOS13904.1 - 1.9e-80 270.1 0.1 3.2e-80 269.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS13904.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KOS13904.1 - 0.022 13.9 0.3 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Adaptin_N PF01602.15 KOS13905.1 - 1.3e-108 363.6 0.0 2e-108 363.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KOS13905.1 - 3.1e-51 173.1 0.0 6.6e-51 172.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KOS13905.1 - 8.7e-15 54.7 4.9 4.3e-05 23.7 0.2 5.9 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.17 KOS13905.1 - 4.9e-05 23.0 9.2 0.1 12.7 0.2 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 KOS13905.1 - 0.0031 17.4 1.1 1.1 9.1 0.0 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 KOS13905.1 - 0.017 15.5 6.1 2.2 8.9 0.2 5.1 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KOS13905.1 - 0.018 14.8 2.3 57 3.7 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat BID PF06393.6 KOS13905.1 - 0.059 12.7 0.2 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 BH3 interacting domain (BID) HEAT_EZ PF13513.1 KOS13905.1 - 0.78 10.3 13.1 0.27 11.7 2.6 4.0 3 1 1 4 4 4 0 HEAT-like repeat Sugar_tr PF00083.19 KOS13906.1 - 1.9e-94 316.7 23.9 2.6e-71 240.5 7.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS13906.1 - 8e-14 51.1 37.7 1.2e-10 40.7 11.4 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KOS13906.1 - 8.5 6.4 13.3 0.21 11.6 0.6 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Spb1_C PF07780.7 KOS13907.1 - 2.5e-72 242.8 23.0 2.5e-72 242.8 16.0 4.0 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 KOS13907.1 - 6.8e-54 182.5 0.3 1.4e-53 181.5 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KOS13907.1 - 2.2e-47 160.5 8.3 2.2e-47 160.5 5.7 5.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) IGR PF09597.5 KOS13908.1 - 4.5e-14 52.0 0.1 8.9e-14 51.1 0.0 1.6 1 1 0 1 1 1 1 IGR protein motif WD40 PF00400.27 KOS13909.1 - 7.8e-25 85.8 11.0 4.4e-10 39.0 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KOS13909.1 - 1.2e-19 69.9 0.0 2.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 KOS13909.1 - 5.7e-06 26.1 0.1 5.7e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Bd3614_N PF14442.1 KOS13909.1 - 0.096 12.6 3.3 0.22 11.4 2.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal R3H-assoc PF13902.1 KOS13909.1 - 0.17 11.8 0.2 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 R3H-associated N-terminal domain Band_7 PF01145.20 KOS13910.1 - 5.3e-26 91.6 1.4 5.3e-26 91.6 1.0 1.5 1 1 1 2 2 2 1 SPFH domain / Band 7 family dCMP_cyt_deam_1 PF00383.17 KOS13911.1 - 8.6e-06 25.3 0.2 1.4e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KOS13911.1 - 2.1e-05 24.5 0.3 0.0011 18.8 0.1 2.3 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KOS13911.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Pribosyltran PF00156.22 KOS13912.1 - 2.1e-19 69.4 0.0 2.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KOS13912.1 - 0.00053 19.2 0.0 0.00071 18.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 KOS13912.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 PRTase ComF-like COX5B PF01215.14 KOS13913.1 - 3.5e-32 110.9 0.0 4.2e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF3797 PF12677.2 KOS13913.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) AhpC-TSA PF00578.16 KOS13915.1 - 5.5e-30 103.6 0.0 6.9e-30 103.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KOS13915.1 - 1.6e-11 43.6 0.0 3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KOS13915.1 - 1.7e-11 43.8 0.0 2.1e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin ERG4_ERG24 PF01222.12 KOS13916.1 - 2.7e-126 421.6 25.0 3.1e-126 421.3 17.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Amidase PF01425.16 KOS13917.1 - 3.2e-87 293.1 1.2 4.7e-87 292.6 0.8 1.2 1 1 0 1 1 1 1 Amidase SRP54 PF00448.17 KOS13918.1 - 6e-77 257.5 0.2 9.5e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KOS13918.1 - 6.2e-26 90.6 16.1 8.2e-24 83.8 0.0 3.7 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 KOS13918.1 - 2e-12 47.0 0.7 4.5e-12 45.9 0.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 KOS13918.1 - 3.7e-06 26.8 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KOS13918.1 - 5.9e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KOS13918.1 - 6.4e-05 23.1 0.0 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KOS13918.1 - 0.00012 21.5 0.1 0.00055 19.4 0.1 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 KOS13918.1 - 0.0016 17.8 0.1 0.0061 15.9 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 KOS13918.1 - 0.0053 17.0 0.2 0.067 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_31 PF13614.1 KOS13918.1 - 0.006 16.5 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain EcsC PF12787.2 KOS13918.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 EcsC protein family ArgK PF03308.11 KOS13918.1 - 0.016 13.9 0.2 0.1 11.3 0.0 2.4 2 1 0 2 2 2 0 ArgK protein APS_kinase PF01583.15 KOS13918.1 - 0.017 14.8 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3052 PF11253.3 KOS13918.1 - 0.024 14.2 0.9 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) AAA_17 PF13207.1 KOS13918.1 - 0.034 14.9 0.1 0.083 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KOS13918.1 - 0.036 12.7 0.1 0.56 8.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 KOS13918.1 - 0.046 13.2 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KOS13918.1 - 0.049 13.0 0.1 0.09 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain Thymidylate_kin PF02223.12 KOS13918.1 - 0.063 12.6 3.2 0.071 12.4 0.1 2.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_16 PF13191.1 KOS13918.1 - 0.13 12.1 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KOS13918.1 - 0.15 11.3 5.2 1.3 8.1 0.1 3.3 3 1 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KOS13918.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 KOS13918.1 - 0.21 10.5 1.7 0.77 8.7 0.0 2.5 3 0 0 3 3 3 0 Anion-transporting ATPase FAD_binding_8 PF08022.7 KOS13919.1 - 1.6e-15 56.8 0.0 3.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KOS13919.1 - 1.9e-15 57.0 0.0 7.4e-10 38.9 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain RRM_1 PF00076.17 KOS13920.1 - 2.2e-16 59.2 0.0 4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS13920.1 - 3.6e-13 49.2 0.0 6.9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13920.1 - 2.5e-10 40.0 0.1 7e-10 38.6 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TGS PF02824.16 KOS13921.1 - 9.5e-22 76.6 0.0 1.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KOS13921.1 - 1.2e-17 63.9 0.1 3e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS13921.1 - 4.5e-09 35.7 0.2 1.3e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS13921.1 - 0.017 14.9 0.3 0.56 10.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 KOS13921.1 - 0.026 15.0 0.0 0.085 13.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KOS13921.1 - 0.09 12.1 0.3 11 5.4 0.0 2.7 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain PALP PF00291.20 KOS13921.1 - 0.11 11.7 0.3 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ArgK PF03308.11 KOS13921.1 - 0.17 10.6 2.6 0.12 11.1 0.5 1.7 2 0 0 2 2 2 0 ArgK protein Proteasome PF00227.21 KOS13922.1 - 4.1e-51 172.9 0.3 9e-51 171.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit Homoserine_dh PF00742.14 KOS13922.1 - 7.9e-46 155.9 0.0 1.6e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KOS13922.1 - 4.9e-16 59.1 0.0 9.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TPR_11 PF13414.1 KOS13923.1 - 2.4e-12 46.3 3.2 5.1e-09 35.6 0.4 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KOS13923.1 - 1.2e-07 31.0 8.0 0.00024 20.7 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13923.1 - 1.2e-06 27.8 8.8 0.0039 16.7 0.1 3.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13923.1 - 0.0037 17.7 4.1 0.055 14.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13923.1 - 0.014 16.0 9.4 2.4 8.9 1.4 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS13923.1 - 0.031 14.4 2.1 0.1 12.7 0.8 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KOS13923.1 - 0.053 13.4 5.1 3.2 7.7 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KOS13923.1 - 0.055 13.8 0.6 2.4 8.5 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS13923.1 - 0.075 12.9 0.7 17 5.3 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 KOS13923.1 - 0.52 10.2 4.3 0.65 9.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KOS13923.1 - 3.1 7.7 6.9 22 5.0 0.8 3.3 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KOS13923.1 - 9.1 6.9 6.5 42 4.9 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Syja_N PF02383.13 KOS13924.1 - 9.4e-88 294.0 0.0 1.3e-87 293.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF615 PF04751.9 KOS13924.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Coq4 PF05019.8 KOS13925.1 - 8.7e-64 214.4 0.0 2.6e-63 212.9 0.0 1.6 1 1 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 tRNA-synt_1c PF00749.16 KOS13926.1 - 7.5e-105 350.0 0.1 1e-104 349.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KOS13926.1 - 7.9e-32 110.3 0.4 1.3e-31 109.6 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KOS13926.1 - 6.2e-07 29.8 0.3 2.2e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS13926.1 - 5.9e-05 22.8 0.7 0.00017 21.3 0.5 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS13926.1 - 0.0016 18.3 0.0 0.0084 16.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KOS13926.1 - 0.072 12.2 0.3 0.19 10.8 0.1 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SUR7 PF06687.7 KOS13927.1 - 2e-14 53.6 14.2 9.6e-14 51.4 9.5 2.1 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KOS13927.1 - 0.00049 19.8 13.3 0.00049 19.8 9.2 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF996 PF06195.8 KOS13927.1 - 0.0071 16.3 12.5 0.012 15.5 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF996) DUF3902 PF13042.1 KOS13927.1 - 0.0084 15.4 5.0 0.012 14.8 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3902) DuoxA PF10204.4 KOS13927.1 - 0.061 12.3 4.8 0.096 11.7 3.3 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor PMP22_Claudin PF00822.15 KOS13927.1 - 1.4 8.5 12.7 0.1 12.2 5.5 1.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Shisa PF13908.1 KOS13927.1 - 1.7 8.8 13.7 0.12 12.5 4.8 2.4 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator LIP PF03583.9 KOS13928.1 - 2.4e-68 230.4 0.0 3e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KOS13928.1 - 4.2e-06 26.8 0.0 7.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KOS13928.1 - 0.00021 20.7 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KOS13928.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS13928.1 - 0.0092 15.2 1.3 0.045 12.9 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KOS13928.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Frataxin_Cyay PF01491.11 KOS13929.1 - 8.4e-31 105.9 0.0 1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DUF3630 PF12305.3 KOS13929.1 - 0.036 13.9 0.0 0.11 12.3 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3630) NMO PF03060.10 KOS13930.1 - 2.9e-59 200.8 3.0 4.2e-59 200.3 2.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS13930.1 - 7.7e-07 28.3 2.0 0.017 14.0 0.0 2.6 1 1 2 3 3 3 2 IMP dehydrogenase / GMP reductase domain DUF1902 PF08972.6 KOS13930.1 - 0.011 15.3 0.6 0.042 13.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Ceramidase PF05875.7 KOS13931.1 - 2e-72 243.5 8.1 2.3e-72 243.2 5.6 1.0 1 0 0 1 1 1 1 Ceramidase adh_short PF00106.20 KOS13932.1 - 2.9e-66 222.5 6.5 4.9e-35 120.9 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KOS13932.1 - 1.2e-32 113.0 4.4 8.2e-18 64.7 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 KOS13932.1 - 1.6e-30 105.0 0.0 3.8e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 KOS13932.1 - 4.4e-17 62.6 1.5 6.7e-08 32.5 0.1 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 KOS13932.1 - 3.3e-12 46.3 0.0 2.5e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KOS13932.1 - 0.0029 16.6 0.2 2.5 7.1 0.0 2.7 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KOS13932.1 - 0.0033 17.0 5.6 0.081 12.5 0.7 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cpn60_TCP1 PF00118.19 KOS13933.1 - 6.5e-142 473.5 0.0 7.4e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PEGSRP PF07623.6 KOS13933.1 - 0.0032 16.7 0.1 0.011 14.9 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1584) Zip PF02535.17 KOS13934.1 - 1.5e-27 96.4 12.8 1.5e-27 96.4 8.8 3.1 1 1 1 2 2 2 1 ZIP Zinc transporter Yip1 PF04893.12 KOS13934.1 - 7.8 5.9 10.3 3.1 7.2 0.7 3.0 3 1 0 3 3 3 0 Yip1 domain TFIID_30kDa PF03540.8 KOS13935.1 - 4.5e-27 93.6 0.2 2.3e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 KOS13935.1 - 4.6e-08 32.7 0.2 0.0035 17.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain Glyco_hydro_88 PF07470.8 KOS13936.1 - 3e-11 42.9 0.0 1.1e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.23 KOS13936.1 - 0.0013 17.2 1.4 0.0058 15.0 0.0 2.6 3 1 0 3 3 3 1 AMP-binding enzyme RRM_6 PF14259.1 KOS13937.1 - 7.6e-34 115.5 0.0 1.3e-18 66.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS13937.1 - 6.9e-30 102.4 0.0 2.5e-20 71.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS13937.1 - 1.9e-21 75.6 0.0 2.3e-09 36.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KOS13937.1 - 4.2e-11 42.9 0.2 1.1e-10 41.6 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 KOS13937.1 - 4.5e-06 26.4 0.2 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KOS13937.1 - 0.0037 17.0 0.1 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 KOS13937.1 - 0.0084 15.5 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4651) Integrase_AP2 PF14657.1 KOS13937.1 - 0.03 14.1 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain His_Phos_2 PF00328.17 KOS13938.1 - 3.6e-22 79.1 0.0 4.4e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3844 PF12955.2 KOS13939.1 - 2.7e-27 94.8 2.5 4.5e-27 94.1 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) AIP3 PF03915.8 KOS13939.1 - 0.13 11.1 0.2 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 HlyD PF00529.15 KOS13939.1 - 0.24 10.6 3.9 0.36 10.1 2.3 1.5 1 1 0 1 1 1 0 HlyD family secretion protein ORC4_C PF14629.1 KOS13940.1 - 1.2e-33 116.2 0.1 2.1e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KOS13940.1 - 3.8e-27 95.4 3.0 3.1e-25 89.2 0.2 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KOS13940.1 - 6e-07 29.7 0.0 0.041 14.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS13940.1 - 7.2e-06 26.1 0.0 0.00011 22.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KOS13940.1 - 0.00032 20.4 0.1 0.046 13.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ORC3_N PF07034.6 KOS13940.1 - 0.00044 19.3 0.3 0.00088 18.3 0.0 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus DAP3 PF10236.4 KOS13940.1 - 0.021 13.7 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 KOS13940.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KOS13940.1 - 0.041 13.6 0.0 0.17 11.6 0.0 2.2 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KOS13940.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 KOS13940.1 - 0.11 12.1 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KOS13940.1 - 0.17 11.5 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 KOS13940.1 - 0.18 10.7 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KOS13940.1 - 0.19 12.0 0.0 0.52 10.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PH PF00169.24 KOS13941.1 - 5.1e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Peptidase_S24 PF00717.18 KOS13942.1 - 0.00012 21.6 0.3 0.0019 17.7 0.2 2.3 1 1 0 1 1 1 1 Peptidase S24-like Pcc1 PF09341.5 KOS13943.1 - 3.9e-17 62.0 0.1 4.5e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Rtt102p PF09510.5 KOS13944.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein PTP_N PF12453.3 KOS13944.1 - 1 9.0 3.5 16 5.2 0.7 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Sen15 PF09631.5 KOS13945.1 - 7.1e-18 64.7 0.0 9.2e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein DUF202 PF02656.10 KOS13946.1 - 2.5e-14 53.2 1.6 5.3e-14 52.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Spo12 PF05032.7 KOS13947.1 - 4.4e-09 35.8 0.3 7.4e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 Spo12 family DUF4440 PF14534.1 KOS13947.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) TPR_11 PF13414.1 KOS13948.1 - 6.9e-09 35.2 9.8 7.8e-07 28.6 1.6 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KOS13948.1 - 3e-07 29.8 5.4 0.0012 18.6 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS13948.1 - 2.6e-06 26.7 0.8 0.0073 15.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS13948.1 - 3.3e-06 27.6 3.2 0.00071 20.1 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS13948.1 - 8.8e-05 22.8 0.5 0.0036 17.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS13948.1 - 0.012 15.5 4.0 1.9 8.4 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KOS13948.1 - 0.016 15.0 0.6 0.044 13.6 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KOS13948.1 - 0.084 13.3 0.2 4.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat V-SNARE PF05008.10 KOS13948.1 - 0.71 10.0 4.9 5.1 7.3 0.6 3.0 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Nop25 PF09805.4 KOS13949.1 - 3.8e-16 59.4 23.2 3.8e-16 59.4 16.1 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) CAF1A PF12253.3 KOS13949.1 - 6.1 7.0 10.5 11 6.1 0.0 2.5 1 1 0 2 2 2 0 Chromatin assembly factor 1 subunit A QCR10 PF09796.4 KOS13950.1 - 2.5e-12 46.2 1.1 3.7e-12 45.7 0.8 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 KOS13950.1 - 0.037 13.7 0.3 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein MIF4G PF02854.14 KOS13951.1 - 7.7e-20 71.1 0.0 4.2e-19 68.7 0.0 2.1 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 KOS13951.1 - 1.7e-15 56.6 0.0 1.4e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 MA3 domain Nop14 PF04147.7 KOS13951.1 - 0.044 11.7 30.5 0.008 14.1 18.2 1.8 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.6 KOS13951.1 - 0.4 8.7 10.6 0.84 7.6 7.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 KOS13951.1 - 1.1 7.1 13.6 2.9 5.8 9.5 1.7 1 0 0 1 1 1 0 CDC45-like protein Sec7 PF01369.15 KOS13952.1 - 2.2e-28 99.2 1.8 3.5e-28 98.5 1.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 KOS13952.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain Remorin_N PF03766.8 KOS13952.1 - 0.14 11.9 1.5 0.26 11.0 0.0 2.1 1 1 1 2 2 2 0 Remorin, N-terminal region DUF3435 PF11917.3 KOS13953.1 - 0.14 10.8 1.6 0.21 10.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) TFIIA PF03153.8 KOS13954.1 - 1.4 8.7 5.8 2 8.2 4.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Init_tRNA_PT PF04179.7 KOS13955.1 - 6.5e-109 364.7 0.0 7.5e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Glyco_hydro_3 PF00933.16 KOS13956.1 - 1.2e-85 287.1 0.0 1.7e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KOS13956.1 - 4.4e-59 199.7 0.3 1.2e-58 198.3 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KOS13956.1 - 1.9e-18 66.1 0.1 3.6e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NADH-u_ox-rdase PF10785.4 KOS13957.1 - 0.059 13.6 1.4 0.066 13.4 1.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Tmemb_185A PF10269.4 KOS13957.1 - 0.073 12.6 2.5 0.084 12.4 1.7 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein DUF2306 PF10067.4 KOS13957.1 - 0.15 12.1 3.9 0.21 11.7 2.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Ni_hydr_CYTB PF01292.15 KOS13957.1 - 0.62 9.4 5.3 0.82 9.0 3.7 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SdpI PF13630.1 KOS13957.1 - 0.89 9.2 4.9 1.2 8.8 3.4 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family WD40 PF00400.27 KOS13959.1 - 3.1e-55 182.1 17.1 2.8e-11 42.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS13959.1 - 0.00044 20.0 0.0 3 7.4 0.0 3.6 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KOS13959.1 - 0.00055 19.4 0.3 0.038 13.4 0.1 3.0 2 1 1 3 3 3 1 PQQ-like domain Resistin PF06954.6 KOS13959.1 - 0.01 16.1 0.4 14 6.0 0.2 3.2 3 0 0 3 3 3 0 Resistin MMS1_N PF10433.4 KOS13959.1 - 0.014 13.5 0.0 2.3 6.2 0.0 2.3 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term 4HBT_2 PF13279.1 KOS13960.1 - 6.6e-18 65.3 0.3 9.9e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KOS13960.1 - 4.5e-07 29.9 0.1 1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KOS13960.1 - 0.00017 20.6 0.0 0.00032 19.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase HIT PF01230.18 KOS13961.1 - 2.1e-23 82.7 0.1 2.6e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KOS13961.1 - 6.5e-12 45.7 0.1 8.5e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KOS13961.1 - 0.0016 18.0 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mob1_phocein PF03637.12 KOS13962.1 - 7.4e-66 221.1 0.1 8.4e-66 220.9 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.24 KOS13963.1 - 5.3e-44 149.6 0.0 1.5e-43 148.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS13963.1 - 3.1e-22 78.2 0.0 6.7e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS13963.1 - 0.00033 20.5 0.0 0.001 18.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mob1_phocein PF03637.12 KOS13964.1 - 8e-59 198.2 0.7 1e-58 197.8 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family Usp PF00582.21 KOS13965.1 - 3.2e-13 50.0 0.1 4.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF4458 PF14660.1 KOS13965.1 - 0.11 12.4 0.5 8.7 6.4 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4458) Ribul_P_3_epim PF00834.14 KOS13966.1 - 1.6e-65 219.9 0.1 2e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KOS13966.1 - 0.00083 18.9 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 KOS13966.1 - 0.02 14.1 0.1 0.051 12.8 0.1 1.8 1 1 0 1 1 1 0 PcrB family TMP-TENI PF02581.12 KOS13966.1 - 0.091 11.8 0.4 0.17 10.9 0.3 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 KOS13966.1 - 0.13 11.5 0.0 0.43 9.8 0.0 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein PG_binding_3 PF09374.5 KOS13966.1 - 0.14 12.1 0.6 0.44 10.5 0.1 2.1 1 1 1 2 2 2 0 Predicted Peptidoglycan domain Gtr1_RagA PF04670.7 KOS13967.1 - 1.4e-82 276.3 0.5 2.4e-82 275.5 0.3 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KOS13967.1 - 6e-07 28.8 0.1 1.5e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KOS13967.1 - 2.6e-05 23.6 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS13967.1 - 7.2e-05 23.2 0.1 0.00068 20.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KOS13967.1 - 0.00017 21.5 0.0 0.00041 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KOS13967.1 - 0.025 14.0 0.0 0.4 10.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KOS13967.1 - 0.036 12.9 0.0 0.087 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Suppressor_APC PF11414.3 KOS13967.1 - 0.037 13.8 0.1 1.2 8.9 0.0 2.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Sigma54_activat PF00158.21 KOS13967.1 - 0.045 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3192 PF11399.3 KOS13967.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) AAA_24 PF13479.1 KOS13967.1 - 0.25 10.8 2.0 2.1 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF1640 PF07798.6 KOS13968.1 - 5.2e-64 215.5 3.6 5.8e-64 215.3 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.13 KOS13968.1 - 0.058 13.1 2.2 0.44 10.2 1.6 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper DSBA PF01323.15 KOS13968.1 - 0.059 12.9 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain FlaC_arch PF05377.6 KOS13968.1 - 0.28 11.0 4.2 4.4 7.2 0.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MMR_HSR1 PF01926.18 KOS13969.1 - 2.6e-16 59.6 0.0 7.3e-15 54.9 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS13969.1 - 5.7e-05 22.4 0.1 0.0003 20.0 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS13969.1 - 0.00011 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KOS13969.1 - 0.00068 18.8 0.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 KOS13969.1 - 0.0097 15.7 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KOS13969.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein SAPS PF04499.10 KOS13969.1 - 0.11 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_HRP PF05403.6 KOS13969.1 - 4.8 6.6 32.4 0.038 13.5 15.0 2.2 2 0 0 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) Peptidase_S9_N PF02897.10 KOS13970.1 - 6.6e-83 278.5 0.6 9.9e-83 278.0 0.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KOS13970.1 - 8.5e-49 165.6 0.8 1.4e-48 164.9 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_A22B PF04258.8 KOS13971.1 - 1.8e-69 234.4 11.0 2.3e-69 234.1 7.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KOS13971.1 - 0.00036 19.7 4.7 0.00036 19.7 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) Gemini_mov PF01708.11 KOS13971.1 - 0.0063 16.0 0.7 3.2 7.3 0.0 2.7 2 0 0 2 2 2 2 Geminivirus putative movement protein DUF1430 PF07242.6 KOS13971.1 - 2.1 8.4 7.8 2.1 8.4 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) UDG PF03167.14 KOS13972.1 - 1.6e-23 82.8 0.1 4.1e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Glyco_transf_20 PF00982.16 KOS13973.1 - 4e-181 602.6 0.0 3.7e-136 454.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Calpain_III PF01067.17 KOS13974.1 - 9.1e-10 38.3 0.0 1.7e-06 27.7 0.0 3.4 2 2 0 2 2 2 2 Calpain large subunit, domain III PPC PF04151.10 KOS13974.1 - 0.14 13.1 0.0 5.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Med17 PF10156.4 KOS13976.1 - 1.3e-14 53.3 0.0 1.6e-06 26.6 0.0 2.0 2 0 0 2 2 2 2 Subunit 17 of Mediator complex CDV3 PF15359.1 KOS13976.1 - 0.74 9.9 3.2 18 5.3 0.0 2.9 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Laminin_II PF06009.7 KOS13977.1 - 0.0021 17.8 8.4 0.0021 17.8 5.8 5.2 1 1 4 6 6 6 1 Laminin Domain II Reo_sigmaC PF04582.7 KOS13977.1 - 0.069 12.3 28.1 0.033 13.3 2.9 3.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein IFT57 PF10498.4 KOS13977.1 - 1.3 7.7 52.6 0.036 12.8 6.4 3.2 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 DUF641 PF04859.7 KOS13977.1 - 1.5 8.5 49.6 0.26 11.0 6.6 5.4 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KOS13977.1 - 3 7.3 70.5 0.45 10.0 5.8 4.3 1 1 3 4 4 4 0 IncA protein TrkH PF02386.11 KOS13978.1 - 2.7e-83 279.4 17.1 8.7e-81 271.2 5.6 2.1 2 0 0 2 2 2 2 Cation transport protein Y_phosphatase PF00102.22 KOS13979.1 - 3.5e-57 193.4 0.4 5.4e-56 189.5 0.2 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KOS13979.1 - 1.3e-06 28.6 0.0 9.1e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.15 KOS13979.1 - 0.028 14.0 0.1 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KOS13979.1 - 0.12 12.5 1.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family zf-CCCH_2 PF14608.1 KOS13980.1 - 1.5e-06 27.9 37.9 0.0072 16.2 0.8 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type MMR_HSR1 PF01926.18 KOS13981.1 - 2.2e-12 46.9 0.0 4.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 KOS13981.1 - 0.004 16.0 0.1 0.0073 15.1 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KOS13981.1 - 0.012 14.9 0.1 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 KOS13981.1 - 0.026 13.7 0.2 0.15 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS13981.1 - 0.027 13.9 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS13981.1 - 0.043 13.9 0.3 3.5 7.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 KOS13981.1 - 0.073 13.5 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Transposase_24 PF03004.9 KOS13981.1 - 0.1 12.4 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Pol_alpha_B_N PF08418.5 KOS13981.1 - 0.12 11.9 0.2 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SLD3 PF08639.5 KOS13982.1 - 1.4e-06 27.2 0.0 2.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication regulator SLD3 FA_hydroxylase PF04116.8 KOS13982.1 - 0.085 13.2 0.1 0.81 10.1 0.0 2.2 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily Mid2 PF04478.7 KOS13983.1 - 4.4e-05 22.9 3.1 6.3e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 KOS13983.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sensor PF13796.1 KOS13983.1 - 0.0099 15.4 3.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Putative sensor SKG6 PF08693.5 KOS13983.1 - 0.025 13.9 0.6 0.11 11.8 0.4 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF566 PF04484.7 KOS13983.1 - 1 8.7 25.6 2.6 7.4 17.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF566) PGP_phosphatase PF09419.5 KOS13984.1 - 4.4e-44 149.8 0.0 6.5e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KOS13984.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Prp19 PF08606.6 KOS13984.1 - 0.12 12.1 1.3 3.3 7.5 0.2 2.8 2 0 0 2 2 2 0 Prp19/Pso4-like PNRC PF15365.1 KOS13984.1 - 8.3 6.5 9.8 11 6.1 1.1 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator K_oxygenase PF13434.1 KOS13985.1 - 6.3e-96 321.2 0.0 7.5e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KOS13985.1 - 1.9e-08 34.6 0.0 6e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS13985.1 - 2.6e-06 27.2 0.2 2.4e-05 24.1 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS13985.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2985 PF11204.3 KOS13986.1 - 2.9e-24 84.6 6.4 5e-24 83.8 4.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) HlyIII PF03006.15 KOS13987.1 - 9.1e-55 185.4 21.4 1.2e-54 185.0 14.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.10 KOS13987.1 - 0.033 14.2 10.6 0.19 11.7 0.6 3.4 1 1 2 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family SecE PF00584.15 KOS13988.1 - 2.3e-14 52.7 0.0 2.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex BofA PF07441.6 KOS13988.1 - 0.039 13.9 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 SigmaK-factor processing regulatory protein BofA MBOAT PF03062.14 KOS13988.1 - 0.07 12.2 0.0 0.071 12.2 0.0 1.0 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family ABM PF03992.11 KOS13990.1 - 4.5e-07 29.8 1.4 1.1e-06 28.5 1.0 1.6 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Spt5-NGN PF03439.8 KOS13991.1 - 9.9e-19 66.8 0.0 2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 KOS13991.1 - 8.7e-17 61.6 60.4 2e-09 37.9 12.3 3.1 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 KOS13991.1 - 2.7e-16 58.5 12.1 9.4e-06 25.1 0.1 5.5 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.3 KOS13991.1 - 3.8e-12 46.6 16.3 3.8e-12 46.6 11.3 3.2 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Tox-HDC PF15656.1 KOS13991.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature IlvN PF07991.7 KOS13992.1 - 2.2e-44 150.7 0.0 3.3e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KOS13992.1 - 6.1e-42 142.9 0.0 9.7e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KOS13992.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkH PF02386.11 KOS13994.1 - 6.2e-41 140.1 0.6 7.8e-41 139.8 0.4 1.0 1 0 0 1 1 1 1 Cation transport protein DUF1938 PF09153.5 KOS13994.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1938) WD40 PF00400.27 KOS13995.1 - 4.4e-17 61.2 12.3 1.5e-06 27.8 0.5 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat RWD PF05773.17 KOS13995.1 - 0.00032 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain HEAT_2 PF13646.1 KOS13996.1 - 2.2e-31 108.0 82.8 1.6e-08 34.7 0.4 15.1 11 5 5 16 16 16 10 HEAT repeats HEAT PF02985.17 KOS13996.1 - 1.2e-25 87.2 42.2 0.16 12.1 0.1 21.1 22 0 0 22 22 22 7 HEAT repeat DUF3554 PF12074.3 KOS13996.1 - 2.4e-21 76.5 3.3 8.7e-17 61.5 0.1 6.0 6 1 1 7 7 7 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 KOS13996.1 - 3.4e-17 62.3 100.4 0.00012 22.4 0.1 21.8 18 5 7 25 25 25 10 HEAT-like repeat CLASP_N PF12348.3 KOS13996.1 - 2.7e-08 33.4 6.1 0.00037 19.9 0.0 7.2 6 2 3 9 9 9 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KOS13996.1 - 3e-07 30.7 0.0 0.22 11.9 0.0 6.8 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KOS13996.1 - 3.1e-05 22.4 5.1 3.1 6.0 0.1 6.7 6 1 1 7 7 7 2 Adaptin N terminal region RIX1 PF08167.7 KOS13996.1 - 0.0029 17.3 0.8 1.1 8.9 0.0 5.5 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.2 KOS13996.1 - 0.009 15.9 1.6 0.67 9.9 0.1 4.8 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion DUF2669 PF10876.3 KOS13996.1 - 0.06 13.0 0.5 18 5.0 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2669) DUF1649 PF07855.7 KOS13997.1 - 2.8e-11 43.3 0.0 1.4e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) Chromo PF00385.19 KOS13997.1 - 1.3e-06 27.9 0.2 2.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain polyprenyl_synt PF00348.12 KOS13999.1 - 1.6e-50 171.4 0.0 2e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase XPC-binding PF09280.6 KOS13999.1 - 0.019 14.3 0.7 0.2 11.1 0.1 2.5 2 0 0 2 2 2 0 XPC-binding domain SHR3_chaperone PF08229.6 KOS14002.1 - 1.1e-21 76.7 1.1 2.9e-21 75.3 0.7 1.6 1 1 0 1 1 1 1 ER membrane protein SH3 DUF2215 PF10225.4 KOS14002.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) DUF2554 PF10829.3 KOS14002.1 - 0.17 12.0 0.6 3.1 7.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) SH3_1 PF00018.23 KOS14003.1 - 8.5e-12 44.2 0.1 1.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS14003.1 - 8e-11 41.3 0.0 1.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS14003.1 - 6.1e-10 38.4 0.2 1.3e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Shadoo PF14999.1 KOS14003.1 - 5.6 6.8 16.5 0.59 9.9 4.9 2.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Gly-zipper_OmpA PF13436.1 KOS14003.1 - 8.9 6.0 19.7 0.17 11.5 6.2 2.9 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Ima1_N PF09779.4 KOS14005.1 - 1.5e-20 73.9 4.4 1.7e-20 73.8 1.1 2.4 2 1 0 2 2 2 1 Ima1 N-terminal domain DZR PF12773.2 KOS14005.1 - 0.062 13.1 2.3 12 5.8 0.1 3.0 2 2 0 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 KOS14005.1 - 0.38 10.5 10.2 1.1 9.0 0.1 3.5 3 1 1 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) zf-FPG_IleRS PF06827.9 KOS14005.1 - 1.8 8.3 6.4 1.3 8.7 0.2 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS NTR2 PF15458.1 KOS14006.1 - 1e-25 90.4 21.9 2.7e-14 53.0 3.8 2.3 2 0 0 2 2 2 2 Nineteen complex-related protein 2 Tmemb_cc2 PF10267.4 KOS14006.1 - 0.00039 19.1 0.9 0.00064 18.4 0.6 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein V_ATPase_I PF01496.14 KOS14006.1 - 0.1 10.4 0.4 0.15 9.8 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 KOS14006.1 - 0.2 11.3 1.1 0.47 10.1 0.8 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.7 KOS14006.1 - 8.5 5.3 10.4 0.31 10.0 1.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 SNF5 PF04855.7 KOS14007.1 - 9e-61 205.4 0.0 1.7e-60 204.5 0.0 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ribosomal_S2 PF00318.15 KOS14007.1 - 4.5e-43 146.9 0.0 6.9e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 PITH PF06201.8 KOS14007.1 - 1.9e-31 108.9 0.0 3.3e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 PITH domain GATA PF00320.22 KOS14007.1 - 0.0014 17.9 2.8 0.0038 16.5 1.9 1.8 1 1 0 1 1 1 1 GATA zinc finger Mito_carr PF00153.22 KOS14008.1 - 2.8e-55 184.0 8.5 1.4e-19 69.6 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KOS14008.1 - 0.5 10.4 0.0 0.5 10.4 0.0 2.9 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family TP_methylase PF00590.15 KOS14009.1 - 1.1e-13 51.3 0.2 3.1e-13 49.9 0.0 2.0 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Complex1_LYR PF05347.10 KOS14010.1 - 5.2e-05 22.9 0.0 5.2e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS14010.1 - 0.028 14.6 0.2 0.055 13.6 0.2 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Ribosomal_60s PF00428.14 KOS14011.1 - 2.1e-26 92.1 10.8 2.6e-26 91.8 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S21 PF01165.15 KOS14012.1 - 2.3e-11 42.9 7.0 4.2e-11 42.1 4.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 DUF2013 PF09431.5 KOS14013.1 - 3.4e-32 111.1 0.2 6.1e-32 110.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Golgin_A5 PF09787.4 KOS14013.1 - 1.1 7.6 3.3 1.7 7.0 2.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Clat_adaptor_s PF01217.15 KOS14014.1 - 1e-49 167.9 2.0 1.4e-49 167.4 1.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MAT1 PF06391.8 KOS14015.1 - 7.6e-35 120.3 31.4 1.1e-34 119.8 21.7 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KOS14015.1 - 1.3e-06 27.9 6.5 1.2e-05 24.9 5.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KOS14015.1 - 1.9e-06 27.4 7.2 6.2e-06 25.7 5.1 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS14015.1 - 3.5e-06 26.5 4.3 7.5e-06 25.5 3.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS14015.1 - 1.5e-05 24.9 7.7 7.3e-05 22.7 5.7 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS14015.1 - 3.4e-05 23.5 7.4 0.00013 21.7 5.4 1.8 1 1 1 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 KOS14015.1 - 0.021 14.4 4.6 0.16 11.6 1.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KOS14015.1 - 0.029 14.4 0.6 0.064 13.3 0.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Rad50_zn_hook PF04423.9 KOS14015.1 - 0.037 13.5 5.6 0.6 9.6 0.0 3.5 3 1 0 3 3 3 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 KOS14015.1 - 0.081 12.6 4.2 0.083 12.6 1.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger GAGA PF09237.6 KOS14015.1 - 0.087 12.4 1.5 1.3 8.7 0.2 2.5 2 0 0 2 2 2 0 GAGA factor DZR PF12773.2 KOS14015.1 - 0.31 10.8 3.7 0.89 9.4 2.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.1 KOS14015.1 - 0.78 9.3 7.2 5.3 6.6 3.1 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Nop53 PF07767.6 KOS14015.1 - 0.85 8.5 25.5 1.2 8.0 17.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) LMBR1 PF04791.11 KOS14015.1 - 0.85 8.1 3.7 1 7.8 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C3HC4_4 PF15227.1 KOS14015.1 - 1.4 8.8 7.5 4.9 7.0 5.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Antimicrobial10 PF08105.6 KOS14016.1 - 0.0036 16.9 0.1 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 Metchnikowin family Metallophos PF00149.23 KOS14016.1 - 0.022 14.1 6.1 0.31 10.3 4.2 2.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase zf-DHHC PF01529.15 KOS14017.1 - 7.9e-44 149.1 0.0 1.3e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KOS14017.1 - 0.049 13.4 0.5 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 KOS14017.1 - 0.45 10.3 8.1 0.86 9.4 5.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KOS14017.1 - 6.7 6.3 6.3 11 5.6 4.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain eIF2A PF08662.6 KOS14018.1 - 3.8e-80 268.1 0.0 3.4e-76 255.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KOS14018.1 - 0.0065 16.3 0.2 2.9 7.9 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 KOS14018.1 - 1.4 9.0 10.8 0.12 12.4 1.8 2.8 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 HSP70 PF00012.15 KOS14019.1 - 1.5e-240 799.2 4.2 1.8e-240 799.0 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS14019.1 - 3e-18 65.5 0.4 1.9e-17 62.8 0.2 1.9 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KOS14019.1 - 0.003 16.4 0.6 0.033 13.0 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 KOS14019.1 - 0.013 14.4 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 StbA protein BcrAD_BadFG PF01869.15 KOS14019.1 - 0.039 13.2 0.1 2 7.6 0.0 2.5 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 KOS14019.1 - 0.039 13.0 0.6 0.11 11.5 0.2 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase QRPTase_N PF02749.11 KOS14019.1 - 0.053 13.3 0.1 7.5 6.4 0.0 3.1 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain FGGY_C PF02782.11 KOS14019.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Lectin_leg-like PF03388.8 KOS14020.1 - 6.7e-60 202.0 0.1 9.3e-60 201.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KOS14020.1 - 3e-05 23.4 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Aminotran_1_2 PF00155.16 KOS14021.1 - 4.7e-57 193.5 0.0 5.8e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KOS14021.1 - 0.0088 14.3 0.0 0.014 13.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS14021.1 - 0.022 13.4 0.0 0.041 12.6 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V FMN_dh PF01070.13 KOS14022.1 - 1.1e-115 386.2 0.0 1.5e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KOS14022.1 - 1.6e-40 136.7 0.1 1.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KOS14022.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KOS14022.1 - 0.0006 18.8 0.0 0.00096 18.1 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_C41 PF05417.6 KOS14022.1 - 0.033 13.7 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Hepatitis E cysteine protease NMO PF03060.10 KOS14022.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase PrmA PF06325.8 KOS14023.1 - 1.8e-12 47.0 0.0 3.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KOS14023.1 - 7.1e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS14023.1 - 3.2e-10 40.0 0.1 1.8e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS14023.1 - 8e-09 36.0 0.0 2.3e-08 34.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS14023.1 - 1.2e-07 32.1 0.1 8.7e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS14023.1 - 1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KOS14023.1 - 7.2e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KOS14023.1 - 7.7e-06 25.0 0.0 2.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 KOS14023.1 - 2.6e-05 24.5 0.0 9.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14023.1 - 3.4e-05 24.2 0.0 0.00014 22.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KOS14023.1 - 0.00014 21.0 0.0 0.00033 19.8 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 KOS14023.1 - 0.00031 21.5 0.1 0.0011 19.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KOS14023.1 - 0.00074 18.3 0.0 0.0016 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 KOS14023.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 KOS14023.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KOS14023.1 - 0.055 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 KOS14023.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KOS14023.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB G-alpha PF00503.15 KOS14024.1 - 6.4e-123 410.2 0.0 7.8e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KOS14024.1 - 1.9e-13 50.0 2.7 1.3e-08 34.3 0.1 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS14024.1 - 0.00013 21.1 2.1 0.034 13.2 1.4 2.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS14024.1 - 0.03 14.2 0.1 11 5.9 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 KOS14024.1 - 0.031 14.7 0.1 0.68 10.4 0.0 2.6 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KOS14024.1 - 0.049 13.1 0.1 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KOS14024.1 - 0.085 12.2 0.1 5.8 6.3 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Hexapep PF00132.19 KOS14025.1 - 4.2e-09 35.5 7.3 0.055 13.0 0.4 4.4 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS14025.1 - 8.6e-05 22.0 5.0 0.00082 18.8 0.1 3.2 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KOS14025.1 - 0.00068 18.3 0.2 0.00096 17.8 0.1 1.3 1 1 0 1 1 1 1 L-fucokinase UPF0220 PF05255.6 KOS14026.1 - 4.9e-45 152.7 0.0 6.1e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4131 PF13567.1 KOS14026.1 - 0.052 12.9 3.7 3.6 6.9 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Uso1_p115_head PF04869.9 KOS14027.1 - 2e-53 181.2 0.0 8.8e-53 179.0 0.0 2.1 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region MscS_porin PF12795.2 KOS14027.1 - 0.071 12.4 40.1 0.074 12.3 25.7 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4201 PF13870.1 KOS14027.1 - 0.39 10.1 17.3 0.1 12.0 2.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.5 KOS14027.1 - 1 9.5 10.9 1.8 8.6 4.5 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 KOS14027.1 - 1.4 8.1 24.6 1.4 8.1 3.3 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KOS14027.1 - 3.6 7.3 34.6 12 5.6 2.0 3.7 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 KOS14027.1 - 3.7 4.7 30.9 6.3 3.9 21.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.8 KOS14027.1 - 4.7 7.1 37.7 2.5e+03 -1.7 24.5 3.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.6 KOS14027.1 - 5.1 5.6 22.9 6.5 5.3 4.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 KOS14027.1 - 7.2 7.4 7.1 6.3 7.5 1.7 2.7 1 1 1 2 2 2 0 Occludin homology domain PUF PF00806.14 KOS14029.1 - 8.1e-11 40.7 0.0 0.014 14.8 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat LNP1 PF15419.1 KOS14030.1 - 0.049 13.7 0.1 0.049 13.7 0.1 3.1 3 0 0 3 3 3 0 Leukemia NUP98 fusion partner 1 Reo_sigmaC PF04582.7 KOS14030.1 - 0.051 12.7 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ERM PF00769.14 KOS14030.1 - 0.22 11.0 22.5 0.14 11.6 3.5 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Ax_dynein_light PF10211.4 KOS14030.1 - 4.1 7.1 11.0 0.063 13.1 1.4 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain GLTSCR1 PF15249.1 KOS14031.1 - 3.3e-13 49.6 1.7 7.2e-13 48.5 1.2 1.6 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region Pyr_redox_3 PF13738.1 KOS14032.1 - 1.1e-18 68.0 0.0 3.4e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KOS14032.1 - 4.5e-07 28.4 0.0 1e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KOS14032.1 - 2.3e-06 26.7 0.0 0.0034 16.3 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KOS14032.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS14032.1 - 5.8e-06 26.3 0.0 7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS14032.1 - 9e-05 22.8 0.0 0.067 13.6 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KOS14032.1 - 0.00042 19.3 0.1 0.086 11.7 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KOS14032.1 - 0.00079 19.2 0.0 0.39 10.4 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KOS14032.1 - 0.0018 17.2 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Abhydrolase_6 PF12697.2 KOS14034.1 - 6.5e-30 104.7 2.0 6.5e-30 104.7 1.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS14034.1 - 1.1e-18 67.6 0.0 6.8e-18 65.0 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS14034.1 - 7.2e-14 51.7 0.1 2.3e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KOS14034.1 - 9.2e-07 28.5 0.0 0.015 14.7 0.0 3.4 3 1 1 4 4 4 2 Phospholipase/Carboxylesterase Esterase PF00756.15 KOS14034.1 - 1.2e-06 28.1 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KOS14034.1 - 6.3e-05 22.6 0.0 0.003 17.1 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KOS14034.1 - 6.4e-05 22.7 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 KOS14034.1 - 7.2e-05 22.4 0.1 0.00034 20.2 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KOS14034.1 - 0.00034 19.7 0.0 0.048 12.7 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 KOS14034.1 - 0.0017 16.9 0.0 0.0028 16.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 KOS14034.1 - 0.0034 16.8 0.0 0.0082 15.5 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KOS14034.1 - 0.0069 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Peptidase_S9 PF00326.16 KOS14034.1 - 0.019 14.1 0.0 0.091 11.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KOS14034.1 - 0.038 13.8 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase Lipase_3 PF01764.20 KOS14034.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 KOS14034.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.7 KOS14034.1 - 0.18 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PTPA PF03095.10 KOS14035.1 - 1.5e-96 323.1 0.0 2.7e-96 322.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RFX5_DNA_bdg PF14621.1 KOS14036.1 - 0.0093 15.6 3.5 1.1 8.7 0.1 2.2 2 0 0 2 2 2 2 RFX5 DNA-binding domain AT_hook PF02178.14 KOS14036.1 - 1.6 8.6 30.4 0.33 10.7 4.3 3.6 3 0 0 3 3 3 0 AT hook motif PAT1 PF09770.4 KOS14036.1 - 3.5 5.7 11.6 3.5 5.7 8.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GATase_2 PF00310.16 KOS14037.1 - 8.1e-22 77.4 0.9 9.5e-18 64.0 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KOS14037.1 - 6.1e-15 55.3 0.0 1.3e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KOS14037.1 - 6.9e-13 48.4 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KOS14037.1 - 2.7e-12 46.5 0.1 4.9e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KOS14037.1 - 2.5e-06 26.4 0.0 1.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Chitin_synth_1 PF01644.12 KOS14038.1 - 1.2e-64 217.0 0.0 1.7e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KOS14038.1 - 1.7e-27 96.0 0.6 6.3e-22 77.6 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KOS14038.1 - 5.2e-24 83.7 0.0 3.8e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 KOS14038.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PACT_coil_coil PF10495.4 KOS14038.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein NUDIX PF00293.23 KOS14039.1 - 8.2e-16 57.8 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CWC25 PF12542.3 KOS14040.1 - 1.1e-23 83.4 1.2 1.1e-23 83.4 0.9 3.7 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 KOS14040.1 - 9.6e-15 54.3 14.2 9.6e-15 54.3 9.9 3.2 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Coatomer_E PF04733.9 KOS14043.1 - 5.4e-34 117.7 0.1 6.2e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit Apc3 PF12895.2 KOS14043.1 - 0.0084 16.2 0.0 5.1 7.2 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KOS14043.1 - 0.19 12.2 2.5 7.7 7.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS14043.1 - 0.8 10.3 10.0 0.35 11.4 0.8 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Pribosyltran PF00156.22 KOS14044.1 - 2e-15 56.6 0.2 3.2e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 KOS14044.1 - 0.013 14.8 0.1 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Mito_carr PF00153.22 KOS14045.1 - 1.9e-61 203.7 2.6 4.5e-20 71.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2835 PF11197.3 KOS14045.1 - 0.018 14.8 0.1 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) 2-oxoacid_dh PF00198.18 KOS14046.1 - 2.1e-80 269.3 0.2 2.7e-80 268.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KOS14046.1 - 9.6e-20 70.0 0.7 2.2e-19 68.8 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KOS14046.1 - 1.2e-15 56.8 0.2 2.5e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain DUF3464 PF11947.3 KOS14046.1 - 0.043 13.2 4.3 0.34 10.3 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) HlyD_2 PF12700.2 KOS14046.1 - 0.21 10.7 3.2 0.54 9.3 2.0 1.7 1 1 1 2 2 2 0 HlyD family secretion protein SspB PF04386.8 KOS14046.1 - 1.4 8.4 7.8 2.3 7.8 4.3 2.1 2 0 0 2 2 2 0 Stringent starvation protein B ATP11 PF06644.6 KOS14046.1 - 3.5 7.0 6.9 7.1 6.0 4.8 1.4 1 0 0 1 1 1 0 ATP11 protein RR_TM4-6 PF06459.7 KOS14046.1 - 4.5 7.0 9.5 7.9 6.2 6.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DSHCT PF08148.7 KOS14047.1 - 2.1e-56 190.0 0.3 4.5e-56 188.9 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KOS14047.1 - 9.1e-22 77.3 0.1 1.7e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KOS14047.1 - 6.1e-08 32.1 0.0 3.4e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 KOS14047.1 - 5.9e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS14047.1 - 0.003 17.4 0.1 0.012 15.4 0.1 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2750 PF11042.3 KOS14047.1 - 0.056 13.4 0.1 0.34 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2750) DASH_Dad4 PF08650.5 KOS14048.1 - 1.4e-20 72.9 7.1 1.6e-20 72.7 4.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 KOS14048.1 - 3.8e-05 23.2 2.0 5e-05 22.9 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 GM_CSF PF01109.12 KOS14048.1 - 0.059 13.3 0.3 0.07 13.0 0.2 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor ALS_ss_C PF10369.4 KOS14049.1 - 1.7e-20 72.4 0.0 7.6e-18 64.0 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 KOS14049.1 - 5e-10 38.6 0.1 9.6e-10 37.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KOS14049.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KOS14049.1 - 0.03 14.0 0.6 0.2 11.3 0.1 2.4 2 1 0 2 2 2 0 ACT domain ACT_7 PF13840.1 KOS14049.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 ACT domain TIM PF00121.13 KOS14050.1 - 7.7e-91 303.4 0.0 8.7e-91 303.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase UPF0160 PF03690.8 KOS14051.1 - 1.8e-120 402.2 0.0 2e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Bax1-I PF01027.15 KOS14052.1 - 1.4e-34 119.5 9.2 2e-34 118.9 6.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ATP_bind_1 PF03029.12 KOS14053.1 - 3.8e-73 245.9 3.3 4.3e-67 226.1 0.0 2.9 1 1 2 3 3 3 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KOS14053.1 - 1e-07 31.5 0.0 2.9e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS14053.1 - 9.7e-06 25.5 0.0 3.7e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS14053.1 - 2.7e-05 24.9 0.0 6.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KOS14053.1 - 7e-05 22.3 0.2 0.00024 20.5 0.0 1.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 KOS14053.1 - 8.3e-05 22.4 1.1 0.00021 21.1 0.2 2.1 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 KOS14053.1 - 0.0001 21.8 0.5 0.0015 18.0 0.3 2.1 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 KOS14053.1 - 0.00013 21.5 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KOS14053.1 - 0.00022 21.7 0.0 0.095 13.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KOS14053.1 - 0.00048 20.2 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 KOS14053.1 - 0.001 18.4 0.1 0.054 12.8 0.0 2.4 3 0 0 3 3 2 1 Ras family AAA_25 PF13481.1 KOS14053.1 - 0.0011 18.4 1.5 0.029 13.7 1.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS14053.1 - 0.0013 18.7 0.0 0.0052 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 KOS14053.1 - 0.0015 17.3 0.4 0.14 10.8 0.0 2.2 2 0 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 KOS14053.1 - 0.0017 17.6 0.8 0.013 14.7 0.0 2.4 3 0 0 3 3 2 1 Ferrous iron transport protein B T2SE PF00437.15 KOS14053.1 - 0.0026 16.7 0.1 0.01 14.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 KOS14053.1 - 0.0026 18.0 0.1 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KOS14053.1 - 0.0031 17.2 0.1 0.0066 16.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 KOS14053.1 - 0.0065 15.9 2.9 0.007 15.8 0.2 2.2 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KOS14053.1 - 0.01 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KOS14053.1 - 0.016 15.3 0.0 0.36 11.0 0.0 2.7 2 1 0 2 2 2 0 RNA helicase DUF258 PF03193.11 KOS14053.1 - 0.022 13.9 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KOS14053.1 - 0.024 13.3 0.7 2.5 6.6 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.12 KOS14053.1 - 0.042 13.6 2.3 0.089 12.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 KOS14053.1 - 0.048 13.1 0.8 0.07 12.6 0.1 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain Arf PF00025.16 KOS14053.1 - 0.063 12.5 0.0 5.3 6.2 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family IIGP PF05049.8 KOS14053.1 - 0.073 11.8 0.0 0.44 9.3 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_5 PF07728.9 KOS14053.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KOS14053.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KOS14053.1 - 0.11 12.2 0.0 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KOS14053.1 - 0.14 11.7 1.3 4.7 6.7 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KOS14053.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_28 PF13521.1 KOS14053.1 - 0.16 11.8 1.6 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 KOS14053.1 - 0.17 11.4 0.4 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 KOS14053.1 - 0.18 11.2 1.3 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KOS14053.1 - 1.7 8.4 4.1 2.8 7.7 0.3 2.6 3 0 0 3 3 3 0 Dynamin family AICARFT_IMPCHas PF01808.13 KOS14054.1 - 1.7e-107 359.1 0.0 2.5e-107 358.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KOS14054.1 - 1.1e-20 73.3 0.0 2.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Pantoate_transf PF02548.10 KOS14055.1 - 7e-78 261.3 2.4 1.6e-74 250.3 1.1 2.6 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase ABC_tran PF00005.22 KOS14055.1 - 2.2e-21 76.5 0.0 2.9e-13 50.2 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS14055.1 - 1.5e-05 25.1 0.0 0.017 15.0 0.1 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KOS14055.1 - 3.3e-05 23.7 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit PEP_mutase PF13714.1 KOS14055.1 - 0.00047 19.4 0.7 0.0015 17.7 0.1 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AAA_29 PF13555.1 KOS14055.1 - 0.0019 17.6 0.1 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS14055.1 - 0.0036 17.2 0.3 0.22 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KOS14055.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KOS14055.1 - 0.033 13.2 0.0 4 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 KOS14055.1 - 0.072 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 KOS14055.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS14055.1 - 0.17 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KOS14055.1 - 0.23 10.6 0.1 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein LSM PF01423.17 KOS14056.1 - 4.6e-11 42.1 0.0 7.7e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain SQS_PSY PF00494.14 KOS14056.1 - 0.098 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF3628 PF12300.3 KOS14056.1 - 0.11 12.5 4.3 0.14 12.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) PseudoU_synth_2 PF00849.17 KOS14057.1 - 2.3e-21 76.3 0.0 4.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase RecO_C PF02565.10 KOS14057.1 - 0.032 14.0 0.1 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O C terminal EF-hand_6 PF13405.1 KOS14058.1 - 1.5e-07 30.6 1.7 6.7e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KOS14058.1 - 6.1e-07 29.4 0.8 0.0039 17.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KOS14058.1 - 0.00017 20.6 3.6 0.0043 16.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KOS14058.1 - 0.02 14.5 2.1 0.063 12.8 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_9 PF14658.1 KOS14058.1 - 0.069 13.0 0.1 0.3 11.0 0.0 2.0 3 0 0 3 3 3 0 EF-hand domain CUE PF02845.11 KOS14058.1 - 0.26 10.8 4.2 10 5.6 0.1 2.9 3 0 0 3 3 3 0 CUE domain EF-hand_5 PF13202.1 KOS14058.1 - 0.3 10.4 2.1 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.22 KOS14059.1 - 9.4e-54 181.4 0.0 4e-26 91.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS14059.1 - 8.6e-31 107.3 1.5 2.7e-18 66.3 0.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS14059.1 - 7.9e-12 44.8 0.0 0.0053 16.0 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KOS14059.1 - 1.5e-10 41.3 0.5 0.00019 21.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KOS14059.1 - 4.4e-08 33.4 0.0 0.17 11.8 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KOS14059.1 - 6.1e-08 32.8 0.0 0.00093 19.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS14059.1 - 7.9e-08 31.7 0.1 0.01 15.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KOS14059.1 - 6.3e-05 22.4 1.0 0.086 12.2 0.5 2.8 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KOS14059.1 - 0.00011 23.0 0.0 0.94 10.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KOS14059.1 - 0.00013 21.5 0.3 1.6 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 KOS14059.1 - 0.00015 21.6 0.0 0.43 10.5 0.0 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KOS14059.1 - 0.0002 20.5 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 KOS14059.1 - 0.00067 19.5 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KOS14059.1 - 0.0014 18.3 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 KOS14059.1 - 0.015 13.8 0.0 0.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF815 PF05673.8 KOS14059.1 - 0.016 14.1 0.0 0.59 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KOS14059.1 - 0.022 14.2 0.1 0.63 9.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KOS14059.1 - 0.022 15.0 0.0 16 5.8 0.0 3.0 4 0 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.18 KOS14059.1 - 0.026 14.4 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KOS14059.1 - 0.046 13.5 0.0 15 5.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KOS14059.1 - 0.053 12.2 0.0 8.1 5.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Lysis_S PF04971.7 KOS14059.1 - 0.075 12.7 3.2 0.08 12.6 0.3 2.5 2 0 0 2 2 2 0 Lysis protein S Miro PF08477.8 KOS14059.1 - 0.084 13.3 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KOS14059.1 - 0.12 12.0 0.1 4.9 6.7 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Zeta_toxin PF06414.7 KOS14059.1 - 0.16 11.0 1.1 14 4.6 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin Aminotran_1_2 PF00155.16 KOS14060.1 - 3.3e-94 315.8 0.0 3.8e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cyclin_N PF00134.18 KOS14061.1 - 0.0049 16.4 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KOS14061.1 - 0.42 11.0 0.2 0.42 11.0 0.1 2.1 2 1 0 2 2 2 0 Cyclin Sad1_UNC PF07738.8 KOS14062.1 - 2.1e-28 98.8 0.0 3.5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4407 PF14362.1 KOS14062.1 - 5.5 5.8 14.1 0.076 11.9 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_M28 PF04389.12 KOS14063.1 - 3.4e-31 108.3 0.0 5.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KOS14063.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pro_isomerase PF00160.16 KOS14064.1 - 2.4e-47 161.0 0.1 2.8e-47 160.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PigN PF04987.9 KOS14065.1 - 5.7e-74 249.3 23.3 5.6e-72 242.7 16.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KOS14065.1 - 3.4e-08 33.2 0.6 6.8e-05 22.3 0.1 3.1 3 0 0 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KOS14065.1 - 0.00039 19.7 0.0 0.00067 18.9 0.0 1.4 1 0 0 1 1 1 1 Sulfatase HECT PF00632.20 KOS14066.1 - 9.1e-54 182.7 0.0 1.2e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Acetyltransf_7 PF13508.1 KOS14067.1 - 0.00041 20.4 0.0 0.00084 19.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KOS14067.1 - 0.00061 19.1 0.0 0.00084 18.7 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Acetyltransf_5 PF13444.1 KOS14067.1 - 0.0016 19.0 0.0 0.02 15.4 0.0 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS14067.1 - 0.0028 17.7 0.1 0.039 14.0 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS14067.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family ESSS PF10183.4 KOS14068.1 - 2.2e-20 72.9 1.0 2.8e-20 72.6 0.7 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Exonuc_VII_L PF02601.10 KOS14069.1 - 0.12 11.5 1.3 0.16 11.1 0.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Acetyltransf_5 PF13444.1 KOS14070.1 - 1.1e-07 32.2 0.1 5.1e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS14070.1 - 4.9e-06 26.6 0.4 2e-05 24.7 0.2 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS14070.1 - 1.1e-05 25.3 0.0 3.9e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS14070.1 - 0.00014 21.9 0.0 0.0018 18.4 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KOS14070.1 - 0.022 14.1 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FR47 PF08445.5 KOS14070.1 - 0.089 12.5 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TRAUB PF08164.7 KOS14071.1 - 2.3e-21 75.6 3.0 9.5e-21 73.7 0.0 2.7 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KOS14071.1 - 5.6e-18 65.3 3.5 5.6e-18 65.3 2.4 3.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Daxx PF03344.10 KOS14071.1 - 0.12 10.8 25.2 0.2 10.0 17.4 1.4 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 KOS14071.1 - 7.6 4.0 11.0 9.5 3.7 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Abhydrolase_5 PF12695.2 KOS14072.1 - 9.2e-17 61.1 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS14072.1 - 4.3e-12 46.4 0.1 1.3e-11 44.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KOS14072.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KOS14072.1 - 8.6e-08 32.0 0.0 2e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KOS14072.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF818 PF05677.7 KOS14072.1 - 0.063 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S28 PF05577.7 KOS14072.1 - 0.068 11.7 0.0 0.094 11.2 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HBS1_N PF08938.5 KOS14072.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus DUF2360 PF10152.4 KOS14074.1 - 0.027 14.7 0.4 0.027 14.7 0.3 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Nop53 PF07767.6 KOS14075.1 - 2.2e-77 260.6 26.8 2.6e-77 260.4 18.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) His_Phos_2 PF00328.17 KOS14077.1 - 1.4e-41 143.0 0.0 2.8e-41 141.9 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) DASH_Ask1 PF08655.5 KOS14078.1 - 7.3e-29 99.3 1.3 1.2e-28 98.6 0.9 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Syntaxin_2 PF14523.1 KOS14078.1 - 0.074 13.0 0.4 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Syntaxin-like protein HIG_1_N PF04588.8 KOS14079.1 - 3.3e-05 23.5 0.2 3.3e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Cid2 PF09774.4 KOS14080.1 - 6.6e-29 100.9 0.4 8.4e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AMP-binding PF00501.23 KOS14081.1 - 3.7e-82 275.9 0.0 4.6e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS14081.1 - 3.6e-10 40.6 0.0 1.1e-09 39.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KOS14081.1 - 0.017 13.6 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF3648 PF12364.3 KOS14081.1 - 0.046 13.7 0.1 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) CBFD_NFYB_HMF PF00808.18 KOS14082.1 - 9.3e-19 67.2 1.9 1.3e-18 66.7 1.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS14082.1 - 2e-11 43.8 0.3 2.9e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UQ_con PF00179.21 KOS14083.1 - 8.6e-40 135.4 0.0 1.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KOS14083.1 - 1.1e-10 40.9 0.1 2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DHHA2 PF02833.9 KOS14084.1 - 8.1e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KOS14084.1 - 3.9e-08 33.0 0.1 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DHH family PIF1 PF05970.9 KOS14085.1 - 9.9e-60 202.3 0.1 2.4e-47 161.6 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KOS14085.1 - 6.5e-22 78.0 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KOS14085.1 - 1.9e-08 34.4 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS14085.1 - 5.4e-05 23.2 0.3 0.00035 20.5 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KOS14085.1 - 7.6e-05 22.3 0.2 0.00021 20.9 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KOS14085.1 - 0.0016 18.3 0.0 0.0062 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KOS14085.1 - 0.0017 18.5 0.0 0.0084 16.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KOS14085.1 - 0.0022 18.3 0.0 0.0093 16.2 0.0 2.0 3 0 0 3 3 1 1 ABC transporter AAA_5 PF07728.9 KOS14085.1 - 0.0028 17.3 0.3 0.048 13.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KOS14085.1 - 0.0028 17.1 0.0 0.0073 15.8 0.0 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KOS14085.1 - 0.0037 16.6 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KOS14085.1 - 0.0041 16.8 0.0 0.48 10.1 0.0 2.4 1 1 0 1 1 1 1 NTPase IstB_IS21 PF01695.12 KOS14085.1 - 0.0059 16.0 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 KOS14085.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KOS14085.1 - 0.0082 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KOS14085.1 - 0.011 15.4 0.0 0.049 13.3 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KOS14085.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KOS14085.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 KOS14085.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 KOS14085.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 KOS14085.1 - 0.042 13.4 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 KOS14085.1 - 0.046 12.3 0.0 0.097 11.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KOS14085.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KOS14085.1 - 0.057 12.1 0.0 0.12 11.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 KOS14085.1 - 0.058 12.3 0.0 0.14 11.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KOS14085.1 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KOS14085.1 - 0.077 13.0 0.1 0.6 10.1 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Helicase_RecD PF05127.9 KOS14085.1 - 0.13 11.8 0.2 0.46 10.1 0.1 1.8 1 1 0 1 1 1 0 Helicase Mito_carr PF00153.22 KOS14086.1 - 3.8e-67 222.0 3.1 6.5e-22 77.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.17 KOS14087.1 - 3.4e-43 147.8 3.2 3.4e-43 147.8 2.2 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 KOS14087.1 - 1.6e-10 41.4 0.0 3.8e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 HEAT PF02985.17 KOS14088.1 - 2.8e-23 79.8 19.2 0.00034 20.4 0.0 10.7 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.1 KOS14088.1 - 5.4e-21 74.6 5.2 1.7e-05 25.0 0.0 8.0 4 3 5 9 9 9 7 HEAT repeats HEAT_EZ PF13513.1 KOS14088.1 - 1.4e-20 73.1 21.2 1.9e-10 40.9 0.0 10.1 9 2 2 11 11 11 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KOS14088.1 - 8.4e-12 45.3 0.0 0.0015 18.8 0.0 5.6 6 1 1 7 7 7 3 Vacuolar 14 Fab1-binding region DUF3437 PF11919.3 KOS14088.1 - 9.2e-06 25.2 0.0 0.055 13.1 0.0 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3437) Arm PF00514.18 KOS14088.1 - 2.1e-05 24.1 12.0 1 9.2 0.0 7.8 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KOS14088.1 - 0.00029 20.2 0.0 0.72 9.1 0.0 4.3 4 1 0 5 5 5 1 CLASP N terminal DUF2435 PF10363.4 KOS14088.1 - 0.019 14.8 0.4 0.7 9.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) MMS19_C PF12460.3 KOS14088.1 - 5 5.7 9.1 9.9 4.7 0.1 4.3 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal SNAP PF14938.1 KOS14089.1 - 1.8e-92 309.5 6.5 2e-92 309.3 4.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.1 KOS14089.1 - 0.00028 19.8 4.1 0.0016 17.3 0.8 2.1 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_12 PF13424.1 KOS14089.1 - 0.0013 18.6 15.2 0.96 9.4 0.2 4.1 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KOS14089.1 - 0.0013 18.3 16.1 0.05 13.2 2.7 3.4 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.1 KOS14089.1 - 0.022 15.4 2.7 0.022 15.4 1.9 4.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14089.1 - 0.058 13.2 14.3 11 6.1 0.1 5.2 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14089.1 - 0.68 10.5 13.0 41 4.9 0.1 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS14089.1 - 0.9 9.7 8.5 6.3 7.0 0.5 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 tRNA-synt_2b PF00587.20 KOS14090.1 - 2.9e-45 153.9 0.0 6.2e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS14090.1 - 7.2e-20 70.7 0.4 1.7e-19 69.5 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 KOS14090.1 - 6.1e-17 61.2 0.0 1.7e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KOS14090.1 - 2.1e-10 40.2 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TauD PF02668.11 KOS14091.1 - 3.7e-44 151.3 0.8 4.6e-44 151.0 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RNase_T PF00929.19 KOS14092.1 - 1.9e-26 93.3 0.0 3.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KOS14092.1 - 0.011 15.2 0.0 0.033 13.6 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease RRM_6 PF14259.1 KOS14093.1 - 6.1e-30 103.0 0.4 1.6e-09 37.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS14093.1 - 1.2e-24 85.6 0.1 3.6e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14093.1 - 5.4e-15 54.9 0.1 0.019 14.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PK PF00224.16 KOS14094.1 - 2.2e-155 516.5 2.2 2.7e-155 516.2 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KOS14094.1 - 7.8e-29 99.6 0.0 2.2e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KOS14094.1 - 6.3e-05 21.9 0.9 0.00029 19.8 0.6 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KOS14094.1 - 0.0051 15.7 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cu-oxidase PF00394.17 KOS14095.1 - 8.8e-42 142.6 0.1 2.1e-37 128.4 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KOS14095.1 - 8.9e-33 112.7 4.9 2e-30 105.0 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KOS14095.1 - 3.9e-25 87.8 7.0 1.5e-22 79.5 0.5 4.0 4 1 0 4 4 4 2 Multicopper oxidase LRR_7 PF13504.1 KOS14096.1 - 2e-07 30.1 3.2 0.56 10.6 0.0 6.6 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 KOS14096.1 - 4.4e-07 29.2 6.3 0.092 12.8 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KOS14096.1 - 1.1e-05 24.7 5.5 0.88 9.8 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 KOS14096.1 - 1.7e-05 24.3 3.8 0.94 9.1 0.0 5.5 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) CTP_transf_1 PF01148.15 KOS14097.1 - 4.8e-09 36.2 6.9 4.8e-09 36.2 4.8 4.2 3 2 2 5 5 5 3 Cytidylyltransferase family DUF3292 PF11696.3 KOS14098.1 - 1.9e-05 22.7 4.6 0.00023 19.1 0.1 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 KOS14098.1 - 0.029 13.8 0.1 0.029 13.8 0.1 3.0 4 0 0 4 4 4 0 Plant phosphoribosyltransferase C-terminal TATR PF03430.8 KOS14098.1 - 0.9 8.0 5.6 1.3 7.5 3.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Spc7 PF08317.6 KOS14099.1 - 1.6e-37 128.8 2.2 2.8e-37 128.1 1.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.4 KOS14099.1 - 0.26 10.2 6.2 4.2 6.2 4.4 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KOS14099.1 - 0.96 7.7 2.1 1.6 7.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 KOS14099.1 - 3.2 7.2 12.6 26 4.3 3.9 3.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Enkurin PF13864.1 KOS14099.1 - 6.6 7.0 13.2 0.4 10.9 3.7 3.1 3 0 0 3 3 3 0 Calmodulin-binding MSC PF09402.5 KOS14100.1 - 4.7e-57 193.2 0.8 2.1e-56 191.0 0.0 2.0 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain zf-DHHC PF01529.15 KOS14100.1 - 5.2e-30 104.1 3.3 2.2e-29 102.0 2.3 2.0 1 1 0 1 1 1 1 DHHC palmitoyltransferase HeH PF12949.2 KOS14100.1 - 3.1e-09 36.1 0.0 5.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain Sec61_beta PF03911.11 KOS14101.1 - 2.5e-16 59.1 0.5 3.3e-16 58.7 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family Mre11_DNA_bind PF04152.9 KOS14102.1 - 2.8e-39 134.7 0.2 2.8e-39 134.7 0.1 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KOS14102.1 - 1.9e-19 69.8 0.7 2.6e-19 69.3 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS14102.1 - 2.1e-06 27.6 1.1 1.2e-05 25.2 0.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MCPVI PF02993.9 KOS14102.1 - 0.39 10.8 7.8 0.91 9.6 5.4 1.6 1 0 0 1 1 1 0 Minor capsid protein VI E1_DerP2_DerF2 PF02221.10 KOS14103.1 - 9.9e-19 67.9 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KOS14103.1 - 2.6e-05 24.2 0.0 7.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 ML-like domain Ank_2 PF12796.2 KOS14104.1 - 1.1e-31 109.0 1.8 3.9e-21 75.1 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS14104.1 - 8e-22 75.9 9.7 5e-10 38.6 0.8 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KOS14104.1 - 4.4e-17 60.4 2.8 2.4e-05 24.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KOS14104.1 - 3.7e-15 55.5 7.7 3e-09 36.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS14104.1 - 5.9e-14 52.1 2.6 2e-07 31.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MBOAT PF03062.14 KOS14105.1 - 2.4e-38 132.0 24.2 2.4e-38 132.0 16.7 2.5 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Med2 PF11214.3 KOS14106.1 - 0.0044 17.0 1.2 0.0069 16.3 0.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF445 PF04286.7 KOS14106.1 - 0.015 14.8 2.7 0.017 14.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2884 PF11101.3 KOS14106.1 - 0.027 13.8 1.7 0.075 12.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Dynamin_M PF01031.15 KOS14106.1 - 0.041 12.6 0.5 0.068 11.9 0.3 1.4 1 1 0 1 1 1 0 Dynamin central region DUF883 PF05957.8 KOS14106.1 - 0.067 13.5 12.0 0.69 10.3 0.9 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF842 PF05811.8 KOS14106.1 - 0.081 12.3 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Prominin PF05478.6 KOS14106.1 - 0.12 9.9 2.2 0.17 9.3 1.4 1.3 1 1 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 KOS14106.1 - 0.52 9.7 8.0 0.92 8.9 5.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Muted PF14942.1 KOS14106.1 - 0.53 10.1 5.2 0.6 9.9 2.1 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2317 PF10079.4 KOS14106.1 - 0.62 8.6 6.3 0.31 9.6 2.9 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Fib_alpha PF08702.5 KOS14106.1 - 0.94 9.6 7.9 0.96 9.5 2.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MT0933_antitox PF14013.1 KOS14106.1 - 1.5 8.9 9.9 1.2 9.2 0.8 3.2 2 2 0 2 2 2 0 MT0933-like antitoxin protein Remorin_C PF03763.8 KOS14106.1 - 1.7 8.2 8.5 0.21 11.1 2.3 2.1 1 1 2 3 3 3 0 Remorin, C-terminal region DUF2823 PF11034.3 KOS14106.1 - 6.2 7.0 19.8 3.7 7.7 0.8 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2823) YtxH PF12732.2 KOS14106.1 - 10 6.6 13.8 1.2e+04 -3.3 9.5 3.5 1 1 0 1 1 0 0 YtxH-like protein Profilin PF00235.14 KOS14107.1 - 2.6e-39 134.0 0.0 2.9e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Mis14 PF08641.7 KOS14108.1 - 1.1e-07 31.9 0.3 2e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like EI24 PF07264.6 KOS14109.1 - 1.4e-21 76.9 16.6 2.1e-21 76.3 11.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ICE2 PF08426.5 KOS14110.1 - 6.6e-40 136.9 17.9 1e-36 126.4 11.3 3.2 1 1 0 1 1 1 1 ICE2 LTV PF04180.9 KOS14111.1 - 6.7e-46 157.6 6.6 6.7e-46 157.6 4.5 2.6 2 1 0 2 2 2 1 Low temperature viability protein Rotamase PF00639.16 KOS14111.1 - 4.5 8.0 9.0 43 4.9 2.8 2.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain PPR_2 PF13041.1 KOS14112.1 - 6.8e-11 41.9 0.0 0.00057 19.8 0.0 6.4 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KOS14112.1 - 0.0013 18.8 20.3 0.33 11.3 0.1 7.9 11 1 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 KOS14112.1 - 0.0088 15.9 0.0 49 4.2 0.0 6.0 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.2 KOS14112.1 - 0.23 10.9 0.0 0.23 10.9 0.0 4.3 5 0 0 5 5 5 0 PPR repeat WD40 PF00400.27 KOS14113.1 - 2.6e-06 27.0 10.8 0.042 13.7 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 KOS14113.1 - 0.014 15.0 0.0 2.1 8.0 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KOS14113.1 - 0.15 11.7 8.2 12 5.6 0.0 4.1 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 KOS14113.1 - 0.21 9.3 1.0 0.91 7.2 0.0 2.4 2 2 0 2 2 2 0 IKI3 family PAF-AH_p_II PF03403.8 KOS14114.1 - 1e-41 142.5 0.0 7.1e-22 77.2 0.0 3.3 4 1 0 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KOS14114.1 - 5.2e-10 39.2 0.0 7.3e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KOS14114.1 - 3.4e-06 26.1 0.0 0.00022 20.1 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 KOS14114.1 - 9.4e-06 24.6 0.0 0.00013 20.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.2 KOS14114.1 - 0.00016 21.6 0.0 0.0017 18.2 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS14114.1 - 0.00029 20.6 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Exo_endo_phos PF03372.18 KOS14116.1 - 4.3e-09 36.6 0.0 7.7e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.14 KOS14117.1 - 1.9e-40 138.3 0.3 2.6e-40 137.9 0.2 1.2 1 0 0 1 1 1 1 Carbonic anhydrase WD40 PF00400.27 KOS14118.1 - 2.2e-22 78.0 8.7 1.7e-05 24.4 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KOS14118.1 - 0.0016 16.7 0.0 0.0033 15.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Rsm22 PF09243.5 KOS14119.1 - 1.1e-35 123.0 2.6 1.1e-24 86.8 0.1 2.5 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Leuk-A4-hydro_C PF09127.6 KOS14120.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal PPR_2 PF13041.1 KOS14120.1 - 0.087 12.8 3.2 1.1 9.3 0.1 3.2 2 1 0 2 2 2 0 PPR repeat family BrkDBD PF09607.5 KOS14120.1 - 0.64 9.6 3.8 1.2 8.7 0.8 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain Polyketide_cyc PF03364.15 KOS14121.1 - 2.2e-23 82.6 0.0 2.6e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KOS14121.1 - 0.0045 17.1 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Es2 PF09751.4 KOS14122.1 - 4.5e-53 181.1 0.0 6.3e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein Es2 Methyltransf_16 PF10294.4 KOS14123.1 - 9.6e-13 47.9 0.1 4.8e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 KOS14123.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KOS14123.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain GST_C_3 PF14497.1 KOS14124.1 - 0.0016 18.8 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WXG100 PF06013.7 KOS14124.1 - 0.056 13.4 0.4 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Acetyltransf_8 PF13523.1 KOS14125.1 - 2.9e-46 157.1 0.1 4.2e-46 156.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KOS14125.1 - 0.00097 19.3 0.2 0.01 16.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain LSM PF01423.17 KOS14127.1 - 8e-18 63.7 0.4 1.2e-17 63.1 0.3 1.3 1 0 0 1 1 1 1 LSM domain V-ATPase_C PF03223.10 KOS14128.1 - 1.3e-115 386.3 5.9 1.4e-115 386.1 4.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF1524 PF07510.6 KOS14128.1 - 0.043 13.6 1.3 0.11 12.3 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) DUF3095 PF11294.3 KOS14128.1 - 0.062 12.3 0.4 0.11 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Peptidase_M1 PF01433.15 KOS14129.1 - 3.2e-63 214.1 0.0 4.6e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 IPPT PF01715.12 KOS14129.1 - 3.4e-48 163.8 0.2 4.2e-28 98.0 0.3 2.5 1 1 1 2 2 2 2 IPP transferase Leuk-A4-hydro_C PF09127.6 KOS14129.1 - 8.1e-40 135.7 0.0 1.6e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KOS14129.1 - 7.8e-14 51.8 0.3 6.4e-13 48.8 0.0 2.5 2 0 0 2 2 2 1 Peptidase MA superfamily AAA_17 PF13207.1 KOS14129.1 - 0.013 16.3 0.0 0.059 14.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS14129.1 - 0.039 13.6 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KOS14129.1 - 0.039 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 KOS14129.1 - 0.048 12.3 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein IPT PF01745.11 KOS14129.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.11 KOS14129.1 - 0.082 12.1 0.2 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 KOS14129.1 - 0.11 12.4 3.9 2 8.3 2.7 2.8 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M61 PF05299.7 KOS14129.1 - 0.14 12.1 2.8 1.4 8.9 1.9 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Asn_synthase PF00733.16 KOS14130.1 - 2.3e-48 164.9 0.1 3.6e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KOS14130.1 - 1.8e-11 43.8 0.0 6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KOS14130.1 - 1.7e-09 37.7 0.0 6.6e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain QueC PF06508.8 KOS14130.1 - 0.16 11.2 0.0 0.8 8.9 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC MFS_1 PF07690.11 KOS14131.1 - 1e-31 109.9 37.2 1e-31 109.9 25.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS14131.1 - 3.5e-12 45.6 20.1 4.9e-12 45.1 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter E1-E2_ATPase PF00122.15 KOS14132.1 - 1.4e-17 63.4 0.0 2.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KOS14132.1 - 5.5e-17 62.5 0.0 2.1e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS14132.1 - 1.3e-13 50.6 0.0 3.1e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KOS14132.1 - 5.3e-12 46.6 7.5 7.9e-11 42.7 5.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS14132.1 - 0.016 14.7 0.1 0.04 13.5 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PspA_IM30 PF04012.7 KOS14132.1 - 0.052 12.8 0.2 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 PspA/IM30 family DUF106 PF01956.11 KOS14133.1 - 1.4e-44 151.5 4.0 4.2e-44 150.0 2.7 1.7 1 1 0 1 1 1 1 Integral membrane protein DUF106 LSM PF01423.17 KOS14134.1 - 1.2e-17 63.2 0.0 1.3e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain Methyltransf_18 PF12847.2 KOS14136.1 - 0.00023 21.7 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS14136.1 - 0.00032 20.4 0.0 0.18 11.5 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14136.1 - 0.00085 18.9 0.0 0.0054 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 KOS14136.1 - 0.0018 18.6 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_26 PF13659.1 KOS14136.1 - 0.0033 17.4 0.8 0.019 14.9 0.6 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS14136.1 - 0.014 15.8 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14136.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14136.1 - 0.05 14.0 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 KOS14136.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PMM PF03332.8 KOS14137.1 - 5.9e-100 333.3 0.0 8e-100 332.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase cwf21 PF08312.7 KOS14137.1 - 5.5e-15 54.9 8.3 5.5e-15 54.9 5.8 2.4 2 0 0 2 2 2 1 cwf21 domain Hydrolase_3 PF08282.7 KOS14137.1 - 9.4e-07 28.6 0.0 1.2e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS14137.1 - 0.054 13.8 0.1 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GTP_cyclohydro2 PF00925.15 KOS14138.1 - 2.1e-60 202.7 0.1 8.1e-55 184.6 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II DOT1 PF08123.8 KOS14139.1 - 5.1e-61 205.5 0.0 6.6e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KOS14139.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCCH PF00642.19 KOS14140.1 - 1e-14 53.7 34.0 0.00013 21.5 0.8 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KOS14140.1 - 0.0001 22.0 2.6 0.0001 22.0 1.8 2.2 2 0 0 2 2 2 1 Zinc knuckle Proteasome PF00227.21 KOS14141.1 - 1.6e-50 171.0 0.0 2e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS14141.1 - 5.7e-14 51.1 0.1 1.3e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PRP3 PF08572.5 KOS14142.1 - 6.9e-62 208.7 7.2 1.1e-61 208.0 5.0 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KOS14142.1 - 1e-32 112.5 0.0 3.2e-32 110.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.13 KOS14142.1 - 0.12 12.5 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Acylphosphatase Not1 PF04054.10 KOS14143.1 - 3.6e-91 305.8 0.0 7.9e-91 304.7 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KOS14143.1 - 5.7e-54 181.7 1.7 3e-53 179.4 1.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) VPS28 PF03997.7 KOS14144.1 - 5.2e-54 182.7 0.0 6.1e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein C2 PF00168.25 KOS14145.1 - 3.2e-50 167.8 0.3 7.7e-15 54.5 0.0 4.5 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 KOS14145.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Acetyltransf_3 PF13302.1 KOS14146.1 - 6.9e-27 94.3 0.0 8.3e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS14146.1 - 5.6e-10 39.3 0.0 1.5e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS14146.1 - 0.0019 18.1 0.0 0.006 16.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS14146.1 - 0.0037 16.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 FR47-like protein DUF3893 PF13032.1 KOS14146.1 - 0.043 13.9 0.1 0.074 13.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3893) ANTH PF07651.11 KOS14147.1 - 6.4e-72 241.5 0.1 6.4e-72 241.5 0.1 2.5 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KOS14147.1 - 1.6e-61 206.6 8.3 1.6e-61 206.6 5.7 4.7 6 1 1 7 7 7 1 I/LWEQ domain ENTH PF01417.15 KOS14147.1 - 0.00025 20.8 0.0 0.0013 18.5 0.0 2.3 1 0 0 1 1 1 1 ENTH domain Peptidase_M28 PF04389.12 KOS14148.1 - 5.8e-25 88.0 0.0 9.3e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KOS14148.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KOS14149.1 - 1.2e-25 88.3 4.8 1.5e-06 27.8 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KOS14149.1 - 0.017 13.9 0.1 0.38 9.4 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Apc4_WD40 PF12894.2 KOS14149.1 - 0.097 12.1 0.0 0.54 9.8 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1805 PF08827.6 KOS14149.1 - 0.097 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) PQQ_3 PF13570.1 KOS14149.1 - 6.6 7.1 15.6 56 4.2 0.0 6.4 6 1 1 7 7 7 0 PQQ-like domain HpcH_HpaI PF03328.9 KOS14150.1 - 3.7e-34 117.5 0.5 4.4e-34 117.2 0.4 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KOS14150.1 - 8.4e-13 47.8 0.7 2.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Med8 PF10232.4 KOS14151.1 - 0.028 13.9 0.9 0.042 13.3 0.3 1.4 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 SWIB PF02201.13 KOS14152.1 - 2.5e-25 87.9 0.0 4.1e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KOS14152.1 - 3.4e-07 29.9 1.5 2.4e-06 27.2 1.0 2.2 1 1 0 1 1 1 1 DEK C terminal domain NARP1 PF12569.3 KOS14152.1 - 1.3 7.6 5.5 1.6 7.3 3.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glycoprotein_G PF00802.14 KOS14152.1 - 2.6 7.1 8.3 3.8 6.5 5.8 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF3708 PF12501.3 KOS14153.1 - 0.012 15.4 1.0 0.041 13.7 0.1 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Phasin PF05597.6 KOS14153.1 - 0.024 14.3 10.8 0.27 10.9 0.9 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3584 PF12128.3 KOS14153.1 - 0.035 11.4 3.9 0.035 11.4 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.10 KOS14153.1 - 0.035 13.2 1.6 0.042 13.0 1.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.13 KOS14153.1 - 0.052 13.0 4.5 0.11 12.0 3.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Borrelia_P83 PF05262.6 KOS14153.1 - 0.069 11.4 10.3 0.075 11.2 7.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ApoLp-III PF07464.6 KOS14153.1 - 0.14 12.1 12.7 0.31 11.0 8.8 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.1 KOS14153.1 - 0.23 11.5 3.5 0.88 9.6 2.4 1.9 1 1 0 1 1 1 0 Syntaxin-like protein Cupin_8 PF13621.1 KOS14153.1 - 0.24 10.8 2.0 0.29 10.5 1.4 1.1 1 0 0 1 1 1 0 Cupin-like domain Senescence PF06911.7 KOS14153.1 - 0.43 10.2 9.4 0.43 10.2 5.6 1.7 1 1 1 2 2 2 0 Senescence-associated protein DUF2317 PF10079.4 KOS14153.1 - 1.5 7.3 6.7 1.9 6.9 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4407 PF14362.1 KOS14153.1 - 1.6 7.5 9.6 2.7 6.8 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 KOS14153.1 - 2.5 7.8 16.1 4.9 6.9 9.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRF PF01765.14 KOS14153.1 - 3.5 7.0 12.9 4.7 6.6 6.9 2.1 2 1 0 2 2 2 0 Ribosome recycling factor Mitofilin PF09731.4 KOS14153.1 - 3.9 6.0 16.8 0.45 9.1 7.6 1.9 2 0 0 2 2 2 0 Mitochondrial inner membrane protein TMP_2 PF06791.8 KOS14153.1 - 6.2 6.3 16.8 2.3 7.8 4.9 3.2 1 1 2 3 3 3 0 Prophage tail length tape measure protein MT0933_antitox PF14013.1 KOS14153.1 - 7.9 6.6 18.8 2.2 8.4 4.4 2.9 1 1 1 2 2 2 0 MT0933-like antitoxin protein Img2 PF05046.9 KOS14154.1 - 1.2e-13 51.0 0.0 3e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RNA_pol_Rpb2_6 PF00562.23 KOS14156.1 - 2.9e-124 414.7 0.4 4.5e-124 414.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS14156.1 - 6.6e-64 214.5 0.0 1.1e-63 213.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KOS14156.1 - 9.9e-49 165.3 0.1 1.9e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KOS14156.1 - 5.3e-28 97.0 0.2 1.6e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KOS14156.1 - 2.1e-26 91.4 0.2 5.7e-26 90.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KOS14156.1 - 2.1e-23 81.8 0.1 4.5e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KOS14156.1 - 2.5e-18 65.7 0.1 5.7e-18 64.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.20 KOS14157.1 - 7.9e-68 228.4 0.0 9.7e-68 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14157.1 - 1.2e-31 109.7 0.0 2.3e-31 108.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14157.1 - 2.8e-08 33.1 0.0 1.4e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS14157.1 - 0.0051 15.9 0.1 0.0097 14.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS14157.1 - 0.076 12.7 4.8 0.1 12.3 0.5 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 KOS14158.1 - 3e-114 381.4 0.0 3.5e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Actin ActA PF05058.7 KOS14158.1 - 0.12 10.3 0.1 0.17 9.8 0.1 1.1 1 0 0 1 1 1 0 ActA Protein FAR1 PF03101.10 KOS14159.1 - 0.0014 19.0 0.1 0.0029 18.0 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4367 PF14285.1 KOS14159.1 - 5.3 6.3 4.8 4.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Rav1p_C PF12234.3 KOS14160.1 - 2.5e-83 280.3 2.9 6.5e-75 252.5 0.1 2.4 2 1 0 3 3 3 2 RAVE protein 1 C terminal DUF2305 PF10230.4 KOS14160.1 - 4.9e-19 68.7 0.0 8.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KOS14160.1 - 6.9e-08 32.6 1.6 6.9e-08 32.6 1.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS14160.1 - 0.00041 20.1 0.0 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS14160.1 - 0.0039 16.7 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 KOS14161.1 - 4.3e-11 43.0 2.3 1.5e-08 34.7 0.4 3.4 1 1 2 3 3 3 2 short chain dehydrogenase KR PF08659.5 KOS14161.1 - 0.0003 20.5 2.2 0.022 14.3 0.7 2.9 1 1 1 2 2 2 1 KR domain DUF2470 PF10615.4 KOS14161.1 - 0.0029 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Coiled PF05710.7 KOS14162.1 - 5.6 7.4 10.6 0.42 11.1 2.9 2.1 1 1 1 2 2 2 0 Coiled coil WES_acyltransf PF03007.11 KOS14163.1 - 1.9e-16 60.3 3.4 1.5e-13 50.9 0.0 3.0 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 KOS14163.1 - 5.7e-06 26.2 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DUF4470 PF14737.1 KOS14163.1 - 0.16 11.7 0.1 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) Pro_isomerase PF00160.16 KOS14164.1 - 7.2e-47 159.4 0.1 8.4e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 4HBT PF03061.17 KOS14165.1 - 8.2e-08 32.2 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Arrestin_N PF00339.24 KOS14166.1 - 4.9e-05 23.1 0.1 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SYS1 PF09801.4 KOS14167.1 - 2.5e-23 82.6 8.3 4e-17 62.5 3.4 2.3 2 1 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network PRELI PF04707.9 KOS14168.1 - 8.6e-24 83.8 0.0 2.4e-23 82.4 0.0 1.7 1 1 0 1 1 1 1 PRELI-like family CCDC155 PF14662.1 KOS14169.1 - 1.1 8.8 38.2 0.09 12.3 4.5 3.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 OstA PF03968.9 KOS14169.1 - 1.4 8.8 8.2 0.14 12.1 2.2 1.8 2 0 0 2 2 2 0 OstA-like protein DUF4172 PF13776.1 KOS14169.1 - 1.5 8.9 6.6 0.63 10.1 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) Spc7 PF08317.6 KOS14169.1 - 2 7.0 34.7 0.77 8.3 13.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GAGA_bind PF06217.7 KOS14169.1 - 2.6 7.9 14.0 3.4 7.5 9.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF972 PF06156.8 KOS14169.1 - 9.7 6.5 27.3 1.2 9.5 2.6 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) F-box-like PF12937.2 KOS14170.1 - 2.6e-05 23.8 9.5 3e-05 23.6 5.1 2.4 2 0 0 2 2 2 1 F-box-like RTC4 PF14474.1 KOS14171.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Pex24p PF06398.6 KOS14173.1 - 9.7e-29 100.2 1.8 9.7e-29 100.2 1.3 3.1 2 1 1 3 3 3 2 Integral peroxisomal membrane peroxin Lyase_1 PF00206.15 KOS14175.1 - 8e-122 406.3 0.0 1.3e-121 405.5 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KOS14175.1 - 5.9e-19 67.8 0.1 1.2e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus BASP1 PF05466.7 KOS14176.1 - 0.29 10.9 3.4 0.35 10.6 2.3 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF2216 PF10226.4 KOS14177.1 - 0.0029 17.1 0.4 0.0034 16.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) bZIP_1 PF00170.16 KOS14177.1 - 0.014 15.3 2.1 0.03 14.2 1.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF904 PF06005.7 KOS14177.1 - 0.023 14.9 4.0 0.043 14.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Peptidase_C37 PF05416.7 KOS14177.1 - 0.027 12.7 0.1 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase HALZ PF02183.13 KOS14177.1 - 0.058 13.1 1.8 0.058 13.1 1.2 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 KOS14177.1 - 0.069 12.7 0.8 0.075 12.6 0.6 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KOS14177.1 - 0.094 13.0 3.8 0.19 12.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF724 PF05266.9 KOS14177.1 - 0.15 11.6 4.6 0.17 11.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.10 KOS14177.1 - 0.16 11.4 3.8 0.28 10.6 2.6 1.5 1 1 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 KOS14177.1 - 0.25 9.1 1.5 0.26 9.0 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 KOS14177.1 - 1.5 8.7 7.9 0.39 10.5 2.5 2.0 1 1 1 2 2 2 0 Basic region leucine zipper CASP_C PF08172.7 KOS14177.1 - 2.1 7.2 8.2 14 4.5 5.7 2.1 1 1 0 1 1 1 0 CASP C terminal Sel1 PF08238.7 KOS14178.1 - 2.2e-13 50.3 5.3 2.8e-07 30.9 0.1 2.8 3 0 0 3 3 3 2 Sel1 repeat DUF3632 PF12311.3 KOS14179.1 - 3.1e-21 76.0 1.0 3.9e-21 75.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) UPF0086 PF01868.11 KOS14180.1 - 1.3e-10 40.7 0.0 2.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 FAM212 PF15342.1 KOS14180.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 FAM212 family Pinin_SDK_memA PF04696.8 KOS14181.1 - 3.2e-06 26.7 4.7 0.0013 18.2 2.9 2.3 2 0 0 2 2 2 2 pinin/SDK/memA/ protein conserved region DUF2937 PF11157.3 KOS14181.1 - 5.7 6.2 11.4 2.4 7.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4078 PF13300.1 KOS14182.1 - 3.4e-14 52.7 2.9 3.4e-14 52.7 2.0 3.0 2 2 1 3 3 3 1 Domain of unknown function (DUF4078) LigB PF02900.13 KOS14183.1 - 7.5e-55 185.8 0.3 9e-55 185.5 0.2 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Phosphoesterase PF04185.9 KOS14184.1 - 7.7e-20 71.4 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoesterase family DHFR_1 PF00186.14 KOS14185.1 - 3.4e-22 78.7 0.0 4.5e-13 49.0 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase Svf1 PF08622.5 KOS14186.1 - 3.3e-91 305.6 0.2 3.8e-91 305.4 0.1 1.0 1 0 0 1 1 1 1 Svf1-like Biotin_lipoyl PF00364.17 KOS14186.1 - 0.081 12.5 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme tRNA-synt_2d PF01409.15 KOS14187.1 - 3.7e-46 157.3 0.0 5.9e-25 87.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KOS14187.1 - 2.8e-25 88.3 0.0 1.1e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain RRM_1 PF00076.17 KOS14188.1 - 2.1e-15 56.1 0.0 3.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14188.1 - 2.3e-14 53.1 0.0 4.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 KOS14188.1 - 2.7e-10 40.4 14.1 2.7e-08 34.0 9.7 2.2 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 KOS14188.1 - 0.00052 19.8 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 KOS14189.1 - 1.1e-42 145.4 0.4 2.3e-30 105.3 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KOS14189.1 - 2.9e-34 116.9 0.1 6.4e-34 115.8 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KOS14189.1 - 8e-09 35.5 0.1 1.2e-05 25.1 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS14189.1 - 7.3e-05 21.9 0.1 0.0021 17.1 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 KOS14189.1 - 0.00071 19.1 0.7 0.045 13.4 0.0 3.0 3 0 0 3 3 3 1 MarR family Arm PF00514.18 KOS14190.1 - 3.5e-93 302.6 10.6 3.2e-13 48.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KOS14190.1 - 9.9e-23 80.2 0.0 1.7e-08 34.5 0.0 5.9 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 KOS14190.1 - 1.6e-21 76.2 10.5 2.7e-21 75.5 7.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KOS14190.1 - 1.1e-19 70.3 0.4 8e-07 29.3 0.0 6.0 5 1 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KOS14190.1 - 8.7e-18 62.7 0.5 3.2e-05 23.6 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 KOS14190.1 - 2.5e-08 33.3 0.0 0.01 14.9 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 KOS14190.1 - 1.6e-06 26.7 0.0 0.0015 16.9 0.0 2.6 1 1 2 3 3 3 2 Adaptin N terminal region RICTOR_V PF14668.1 KOS14190.1 - 0.00021 21.1 4.6 0.064 13.1 0.0 4.3 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 KOS14190.1 - 0.00039 20.3 0.0 0.9 9.4 0.0 4.5 4 1 1 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 KOS14190.1 - 0.0091 16.3 0.6 1.5 9.4 0.0 4.1 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KOS14190.1 - 0.018 13.3 0.2 0.29 9.3 0.0 2.3 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Ric8 PF10165.4 KOS14190.1 - 0.028 13.2 0.0 0.23 10.2 0.0 2.4 2 1 1 3 3 3 0 Guanine nucleotide exchange factor synembryn Mo25 PF08569.6 KOS14190.1 - 0.21 10.5 1.0 0.33 9.9 0.0 1.8 2 0 0 2 2 2 0 Mo25-like DEAD PF00270.24 KOS14191.1 - 2e-43 147.7 0.2 1.6e-42 144.8 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS14191.1 - 2.2e-26 91.4 0.4 6.1e-26 90.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KOS14191.1 - 1.7e-06 27.0 0.0 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KOS14191.1 - 4.9e-06 26.4 0.0 9.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KOS14191.1 - 2.8e-05 22.7 0.0 0.083 11.2 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_19 PF13245.1 KOS14191.1 - 0.0022 17.7 0.1 0.009 15.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Herpes_ori_bp PF02399.10 KOS14191.1 - 0.044 11.7 0.1 0.073 11.0 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_22 PF13401.1 KOS14191.1 - 0.064 13.3 1.1 0.25 11.4 0.3 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KOS14191.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 KOS14191.1 - 0.076 12.9 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain Prok-E2_C PF14459.1 KOS14191.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C CHCH PF06747.8 KOS14192.1 - 0.0009 19.1 4.0 0.0013 18.6 2.8 1.2 1 0 0 1 1 1 1 CHCH domain Rcd1 PF04078.8 KOS14193.1 - 5.1e-128 425.4 0.6 6.5e-128 425.1 0.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PNPOx_C PF10590.4 KOS14194.1 - 9.1e-21 73.0 0.6 1.9e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KOS14194.1 - 5.3e-18 64.8 0.0 1.6e-17 63.2 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF21 PF01595.15 KOS14195.1 - 7.4e-35 119.8 2.5 1.2e-34 119.2 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KOS14195.1 - 1.4e-05 24.7 2.8 0.007 16.1 0.0 2.9 3 0 0 3 3 3 2 CBS domain RhoGAP PF00620.22 KOS14196.1 - 2.9e-36 124.3 0.1 1.1e-35 122.5 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KOS14196.1 - 0.067 13.3 1.2 0.31 11.2 0.0 2.7 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2229 PF09989.4 KOS14196.1 - 0.1 12.0 1.6 0.87 9.0 0.0 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Aldedh PF00171.17 KOS14197.1 - 8.7e-165 548.5 0.0 9.9e-165 548.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KOS14197.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Pro_isomerase PF00160.16 KOS14198.1 - 1.6e-44 151.8 0.2 3e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prefoldin PF02996.12 KOS14198.1 - 3.9e-21 74.9 0.2 9.9e-21 73.6 0.2 1.7 1 0 0 1 1 1 1 Prefoldin subunit TPR_11 PF13414.1 KOS14198.1 - 9.5e-08 31.5 4.7 0.0028 17.2 0.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KOS14198.1 - 1e-06 28.2 9.3 2.6e-05 23.8 0.9 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS14198.1 - 1.8e-05 24.1 5.5 3.3e-05 23.3 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS14198.1 - 0.00016 21.1 0.8 0.00071 19.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14198.1 - 0.00097 19.0 1.3 0.19 11.6 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14198.1 - 0.043 14.4 4.0 0.44 11.3 1.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KOS14198.1 - 0.36 11.5 10.6 4.2 8.1 4.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14198.1 - 1.6 9.3 5.1 1.3 9.6 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_18 PF13238.1 KOS14199.1 - 2e-22 79.8 0.0 5.5e-22 78.4 0.0 1.7 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KOS14199.1 - 4e-14 53.4 0.0 5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS14199.1 - 0.00036 20.5 0.1 0.0012 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS14199.1 - 0.00042 20.2 0.8 0.062 13.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KOS14199.1 - 0.00044 20.2 0.3 0.0015 18.5 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KOS14199.1 - 0.00056 20.1 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KOS14199.1 - 0.00071 19.2 0.1 0.0021 17.7 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain NTPase_1 PF03266.10 KOS14199.1 - 0.00077 19.2 0.5 0.0031 17.2 0.1 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 KOS14199.1 - 0.0024 18.0 0.0 0.0046 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KOS14199.1 - 0.0026 17.1 0.1 0.0074 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KOS14199.1 - 0.0027 16.9 0.0 0.0053 15.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 KOS14199.1 - 0.0033 16.9 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain DUF2075 PF09848.4 KOS14199.1 - 0.0036 16.3 0.2 0.0072 15.3 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ADK PF00406.17 KOS14199.1 - 0.0049 16.7 0.1 0.62 9.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.14 KOS14199.1 - 0.0072 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_22 PF13401.1 KOS14199.1 - 0.0091 16.1 0.0 0.021 14.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 KOS14199.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 KOS14199.1 - 0.015 15.7 0.0 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KOS14199.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 KOS14199.1 - 0.021 13.9 0.3 0.083 11.9 0.0 1.8 2 0 0 2 2 2 0 KaiC Thymidylate_kin PF02223.12 KOS14199.1 - 0.025 13.9 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase IstB_IS21 PF01695.12 KOS14199.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 KOS14199.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KOS14199.1 - 0.034 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KOS14199.1 - 0.048 13.1 0.1 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KOS14199.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 KOS14199.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 KOS14199.1 - 0.055 12.3 0.1 0.098 11.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SKI PF01202.17 KOS14199.1 - 0.06 13.2 0.2 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_14 PF13173.1 KOS14199.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KOS14199.1 - 0.076 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KOS14199.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 KOS14199.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KOS14199.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KOS14199.1 - 0.09 11.6 0.1 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KOS14199.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 KOS14199.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PRK PF00485.13 KOS14199.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 KOS14199.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 KOS14199.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CoaE PF01121.15 KOS14199.1 - 0.21 10.9 0.7 16 4.8 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase HA2 PF04408.18 KOS14200.1 - 7.6e-17 61.2 0.0 7.6e-17 61.2 0.0 2.7 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KOS14200.1 - 2.4e-12 46.6 1.1 2.8e-11 43.2 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KOS14200.1 - 1.3e-10 40.9 0.1 3.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS14200.1 - 3.7e-10 39.5 0.1 7.9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS14200.1 - 4.7e-08 33.2 0.1 7e-07 29.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KOS14200.1 - 0.00026 21.3 2.1 1.1 9.4 3.1 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KOS14200.1 - 0.0014 17.5 0.0 0.0093 14.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KOS14200.1 - 0.0051 17.1 1.8 0.15 12.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter UBA PF00627.26 KOS14200.1 - 0.0061 16.3 0.4 0.035 13.9 0.0 2.6 3 0 0 3 3 3 1 UBA/TS-N domain KaiC PF06745.8 KOS14200.1 - 0.014 14.5 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 KOS14200.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KOS14200.1 - 0.18 11.7 0.1 3.5 7.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain Dus PF01207.12 KOS14201.1 - 3.1e-71 239.7 0.0 4.7e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 KOS14201.1 - 0.14 11.3 0.0 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase DUF1900 PF08954.6 KOS14203.1 - 7.6e-45 151.7 0.0 1.2e-43 147.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KOS14203.1 - 1.1e-20 72.9 1.2 9.1e-20 70.0 0.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KOS14203.1 - 1.1e-11 44.1 0.0 6.2e-05 22.7 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Kinesin-relat_1 PF12711.2 KOS14203.1 - 0.00071 19.9 0.4 0.0039 17.5 0.3 2.2 2 0 0 2 2 2 1 Kinesin motor VID27 PF08553.5 KOS14203.1 - 0.0054 15.0 0.0 0.0054 15.0 0.0 2.4 2 0 0 2 2 2 1 VID27 cytoplasmic protein DUF904 PF06005.7 KOS14203.1 - 0.014 15.6 2.8 0.014 15.6 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TSC22 PF01166.13 KOS14203.1 - 0.038 13.9 2.1 0.087 12.8 1.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3373 PF11853.3 KOS14203.1 - 0.055 11.9 1.8 0.094 11.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SPT16 PF08644.6 KOS14203.1 - 8 6.2 7.4 4.7 7.0 0.3 2.7 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) ER_lumen_recept PF00810.13 KOS14204.1 - 8.7e-51 172.2 12.0 1.2e-50 171.8 8.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KOS14204.1 - 0.48 10.0 15.3 0.25 10.9 0.2 4.0 4 1 1 5 5 5 0 PQ loop repeat Ribosomal_L10 PF00466.15 KOS14205.1 - 0.0046 16.8 0.0 0.22 11.4 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L10 Telomere_Sde2 PF13019.1 KOS14206.1 - 2.8e-31 108.4 0.1 2.8e-31 108.4 0.1 1.6 2 0 0 2 2 2 1 Telomere stability and silencing DUF866 PF05907.8 KOS14207.1 - 2.9e-13 49.6 0.0 3.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 KOS14207.1 - 0.0092 15.5 0.2 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c7 zf-DNA_Pol PF08996.5 KOS14207.1 - 0.19 11.0 0.9 0.34 10.2 0.0 1.7 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DJ-1_PfpI PF01965.19 KOS14208.1 - 1.6e-15 56.8 0.0 3.3e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KOS14208.1 - 2.5e-06 26.9 0.0 6.9e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family VHS PF00790.14 KOS14209.1 - 1.5e-13 50.5 0.0 5.4e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KOS14209.1 - 6.1e-06 26.1 0.3 1.5e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 GAT domain Mannosyl_trans2 PF04188.8 KOS14210.1 - 2.3e-46 158.6 24.1 4e-46 157.8 16.7 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) ING PF12998.2 KOS14211.1 - 3.8e-09 36.7 2.8 6e-09 36.1 1.9 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KOS14211.1 - 4.3e-08 32.7 7.0 6.9e-08 32.0 4.8 1.3 1 0 0 1 1 1 1 PHD-finger HAUS4 PF14735.1 KOS14211.1 - 0.0022 17.3 0.6 0.003 16.9 0.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 TraC PF07820.7 KOS14211.1 - 0.02 15.0 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 TraC-like protein zf-HC5HC2H PF13771.1 KOS14211.1 - 0.023 14.8 0.8 0.047 13.8 0.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KOS14211.1 - 0.27 10.5 2.7 0.57 9.5 1.9 1.6 1 0 0 1 1 1 0 PHD-finger SR-25 PF10500.4 KOS14211.1 - 0.47 9.8 12.1 0.035 13.5 4.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-C4pol PF14260.1 KOS14211.1 - 5.4 7.0 7.4 12 5.9 0.4 3.0 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta GTP_EFTU PF00009.22 KOS14213.1 - 4.3e-48 163.2 0.0 1.1e-47 161.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KOS14213.1 - 7.1e-22 77.0 0.0 1.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KOS14213.1 - 9.8e-15 54.2 0.2 4e-13 49.0 0.1 2.6 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS14213.1 - 4.4e-11 42.7 0.2 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KOS14213.1 - 5.8e-08 32.3 0.0 3.5e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KOS14213.1 - 0.00066 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS14213.1 - 0.13 11.4 0.0 1.3 8.1 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Vps39_2 PF10367.4 KOS14214.1 - 3.3e-05 24.0 0.0 6.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KOS14214.1 - 0.00028 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain HLH PF00010.21 KOS14215.1 - 0.00055 19.5 2.8 0.002 17.8 1.9 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DLIC PF05783.6 KOS14215.1 - 0.15 10.6 0.5 0.38 9.3 0.3 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) BUD22 PF09073.5 KOS14216.1 - 1.9e-50 172.1 32.3 1.3e-38 133.2 8.7 2.0 1 1 1 2 2 2 2 BUD22 Ribosomal_60s PF00428.14 KOS14216.1 - 3 8.2 15.6 0.039 14.3 3.0 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein ATP_bind_3 PF01171.15 KOS14217.1 - 2.1e-16 59.9 0.0 3.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 KOS14217.1 - 0.00064 18.3 0.0 0.00093 17.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 KOS14217.1 - 0.035 13.5 1.3 0.035 13.5 0.9 2.9 4 0 0 4 4 4 0 RecR protein DUF2392 PF10288.4 KOS14217.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) DUF2616 PF11077.3 KOS14217.1 - 0.5 9.8 4.7 0.39 10.1 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) DZR PF12773.2 KOS14217.1 - 8.7 6.2 10.9 3.1 7.6 0.5 3.0 3 0 0 3 3 3 0 Double zinc ribbon Suc_Fer-like PF06999.7 KOS14218.1 - 6.1e-27 95.1 0.0 1.1e-26 94.2 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.22 KOS14218.1 - 2.1e-08 33.7 0.2 2.1e-08 33.7 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FEZ PF07763.8 KOS14219.1 - 0.00061 19.5 0.5 0.014 15.1 0.4 2.2 1 1 1 2 2 2 1 FEZ-like protein Clathrin_bdg PF15045.1 KOS14219.1 - 0.019 14.4 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking FGGY_C PF02782.11 KOS14221.1 - 6e-15 55.3 0.0 1.8e-14 53.7 0.0 1.9 1 1 1 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KOS14221.1 - 1.3e-12 47.5 0.0 4.3e-09 36.0 0.0 3.4 4 0 0 4 4 4 3 FGGY family of carbohydrate kinases, N-terminal domain Phosphoesterase PF04185.9 KOS14222.1 - 2.8e-79 267.0 0.7 5e-79 266.2 0.5 1.3 1 0 0 1 1 1 1 Phosphoesterase family Grp1_Fun34_YaaH PF01184.14 KOS14223.1 - 4.2e-59 199.3 16.9 5.3e-59 199.0 11.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CAAD PF14159.1 KOS14223.1 - 0.044 13.4 1.9 0.073 12.7 0.8 1.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Autophagy_N PF03986.8 KOS14224.1 - 8.4e-39 132.6 0.1 3e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KOS14224.1 - 4e-24 84.5 0.1 1.1e-23 83.1 0.1 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KOS14224.1 - 6.1e-14 50.8 2.6 1.1e-13 50.0 1.8 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal HSP70 PF00012.15 KOS14225.1 - 1.8e-56 191.3 0.7 1.8e-56 191.3 0.5 2.4 2 1 0 2 2 2 1 Hsp70 protein DUF4445 PF14574.1 KOS14225.1 - 0.0029 15.8 0.0 0.006 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4445) HMG-CoA_red PF00368.13 KOS14225.1 - 0.011 14.4 3.7 0.31 9.6 0.2 2.4 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase Pribosyltran PF00156.22 KOS14225.1 - 0.039 13.6 1.1 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain WAC_Acf1_DNA_bd PF10537.4 KOS14226.1 - 6.1e-35 119.4 0.1 2e-34 117.8 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KOS14226.1 - 7.3e-09 35.2 0.3 2.3e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 KOS14226.1 - 3e-06 26.9 0.7 1.3e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KOS14226.1 - 0.00033 20.3 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KOS14226.1 - 0.0021 17.8 0.1 0.0068 16.3 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SAPS PF04499.10 KOS14226.1 - 5 5.6 7.7 3 6.3 2.8 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Bromodomain PF00439.20 KOS14227.1 - 5.4e-22 77.5 0.1 1.2e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KOS14227.1 - 1.9e-05 24.2 0.4 8.6e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 Bromodomain associated Orbi_NS1 PF01718.11 KOS14227.1 - 0.085 10.8 0.0 0.13 10.2 0.0 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein BolA PF01722.13 KOS14229.1 - 7.1e-28 96.3 0.3 8.3e-28 96.1 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein NAD_synthase PF02540.12 KOS14230.1 - 4.6e-26 91.2 0.0 2e-25 89.1 0.0 1.8 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 KOS14230.1 - 2.2e-23 82.5 0.0 4.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 KOS14230.1 - 0.093 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Mito_carr PF00153.22 KOS14231.1 - 3.3e-50 167.7 0.7 4.6e-16 58.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L16 PF00252.13 KOS14232.1 - 3.7e-43 146.4 0.1 4.4e-43 146.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RRS1 PF04939.7 KOS14233.1 - 2.4e-57 192.9 5.2 3.4e-57 192.4 3.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF4051 PF13260.1 KOS14233.1 - 0.27 10.6 0.2 0.27 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Glycos_transf_1 PF00534.15 KOS14234.1 - 9.1e-33 113.0 0.0 5.3e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS14234.1 - 3.3e-15 56.5 0.0 9.2e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KOS14234.1 - 9.5e-14 51.5 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KOS14234.1 - 1.4e-10 41.4 0.0 6.5e-10 39.2 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KOS14234.1 - 0.0018 18.4 0.2 0.29 11.4 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Prenyltransf PF01255.14 KOS14235.1 - 5.2e-71 238.3 0.0 5.9e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rotamase PF00639.16 KOS14236.1 - 6.3e-24 84.5 0.0 1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KOS14236.1 - 5.4e-18 65.3 0.0 6.8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KOS14236.1 - 1.1e-05 26.0 0.0 1.5e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KOS14236.1 - 4.2e-05 23.3 0.8 5.8e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 WW domain Iso_dh PF00180.15 KOS14237.1 - 4.4e-69 233.0 0.0 5.2e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rep_fac_C PF08542.6 KOS14238.1 - 1.1e-19 70.1 0.0 2.3e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KOS14238.1 - 5e-12 46.1 0.0 8.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KOS14238.1 - 6.3e-12 45.4 0.0 2.2e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KOS14238.1 - 7.6e-08 32.5 0.1 6.9e-06 26.1 0.0 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KOS14238.1 - 2.3e-06 27.5 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KOS14238.1 - 1.4e-05 24.0 0.0 0.018 13.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 KOS14238.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS14238.1 - 3.1e-05 24.1 0.0 0.015 15.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS14238.1 - 0.00021 20.4 0.0 0.00066 18.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 KOS14238.1 - 0.00037 20.0 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KOS14238.1 - 0.00075 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 KOS14238.1 - 0.002 17.6 0.0 0.43 9.9 0.0 2.5 1 1 2 3 3 3 1 AAA-like domain ArgK PF03308.11 KOS14238.1 - 0.013 14.2 0.0 0.038 12.7 0.0 1.5 1 1 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 KOS14238.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KOS14238.1 - 0.02 14.6 0.0 0.061 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KOS14238.1 - 0.02 14.0 0.1 0.25 10.4 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KOS14238.1 - 0.035 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KOS14238.1 - 0.045 13.6 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KOS14238.1 - 0.05 13.3 0.1 0.29 10.8 0.0 2.0 1 1 1 2 2 2 0 NTPase SRP54 PF00448.17 KOS14238.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MFS_1 PF07690.11 KOS14240.1 - 9.8e-33 113.3 15.4 1.7e-32 112.5 10.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MNSV_P7B PF06692.6 KOS14240.1 - 0.049 13.4 0.2 0.2 11.4 0.1 2.0 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Peptidase_M50 PF02163.17 KOS14240.1 - 0.49 9.3 3.1 0.27 10.1 0.1 2.0 2 1 0 2 2 2 0 Peptidase family M50 MFS_1 PF07690.11 KOS14241.1 - 3.3e-30 104.9 14.2 5.2e-30 104.3 9.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS14241.1 - 4e-08 32.2 5.9 4.7e-08 32.0 3.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF912 PF06024.7 KOS14241.1 - 0.018 15.1 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Acatn PF13000.2 KOS14242.1 - 2.1e-133 445.7 30.1 8.6e-66 222.5 10.0 3.9 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Iso_dh PF00180.15 KOS14243.1 - 1.6e-119 398.9 0.0 1.8e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF664 PF04978.7 KOS14244.1 - 2.6 8.2 5.8 0.3 11.3 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Grp1_Fun34_YaaH PF01184.14 KOS14245.1 - 1.1e-63 214.3 19.4 1.3e-63 214.0 13.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EXOSC1 PF10447.4 KOS14246.1 - 1.9e-26 91.8 0.0 2.6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KOS14246.1 - 4.7e-05 22.5 2.8 9.2e-05 21.6 0.1 3.0 4 0 0 4 4 4 1 Exosome complex exonuclease RRP4 N-terminal region Sec3_C PF09763.4 KOS14247.1 - 7.7e-124 414.3 0.3 2.8e-120 402.5 0.2 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KOS14247.1 - 2e-12 46.7 0.0 3.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Radical_SAM PF04055.16 KOS14248.1 - 3e-12 47.0 0.0 4.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.6 KOS14248.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal SHOCT PF09851.4 KOS14248.1 - 0.12 11.8 0.5 0.36 10.3 0.3 1.7 1 0 0 1 1 1 0 Short C-terminal domain SIR2_2 PF13289.1 KOS14248.1 - 0.18 11.6 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain UbiA PF01040.13 KOS14249.1 - 3.4e-27 95.3 23.3 4.3e-27 94.9 16.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2408 PF10303.4 KOS14250.1 - 4.1e-47 159.6 2.0 5.4e-33 113.9 0.0 5.2 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) Laminin_II PF06009.7 KOS14250.1 - 1.2 8.9 7.6 1.3 8.8 0.6 3.8 4 1 1 5 5 5 0 Laminin Domain II DUF1604 PF07713.8 KOS14251.1 - 1.2e-37 127.5 2.6 3e-37 126.2 1.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KOS14251.1 - 1.8e-06 27.6 0.3 3.9e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KOS14251.1 - 0.05 13.4 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site COX17 PF05051.8 KOS14252.1 - 1.2e-17 63.6 6.5 1.8e-17 63.0 4.5 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 KOS14252.1 - 0.014 15.2 2.5 0.024 14.5 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Fer4_20 PF14691.1 KOS14252.1 - 0.079 12.5 1.8 0.074 12.6 0.7 1.5 1 1 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster adh_short PF00106.20 KOS14253.1 - 8.2e-29 100.6 2.8 1.1e-28 100.2 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS14253.1 - 1.4e-16 60.6 1.5 2.1e-16 60.0 1.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KOS14253.1 - 8.4e-15 55.1 0.2 1e-14 54.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KOS14253.1 - 0.0071 16.3 0.7 0.027 14.4 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KOS14253.1 - 0.029 13.8 0.7 0.13 11.6 0.5 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KOS14253.1 - 0.05 13.4 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PsbY PF06298.6 KOS14253.1 - 0.12 11.9 1.2 0.26 10.8 0.9 1.6 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) IF-2B PF01008.12 KOS14254.1 - 7.2e-56 189.2 0.0 2.5e-55 187.4 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family ThiF PF00899.16 KOS14256.1 - 5.8e-29 100.6 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KOS14256.1 - 0.00041 20.4 0.0 0.0047 17.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ERO1 PF04137.10 KOS14257.1 - 4.6e-103 344.9 0.0 5.7e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF619 PF04768.8 KOS14258.1 - 5.9e-31 107.1 0.0 8e-20 70.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF619) RESP18 PF14948.1 KOS14259.1 - 0.0022 18.0 0.5 2.9 8.0 0.0 3.2 3 0 0 3 3 3 2 RESP18 domain RcsC PF09456.5 KOS14259.1 - 0.074 12.7 0.0 0.26 10.9 0.0 1.9 1 1 1 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) AAA PF00004.24 KOS14260.1 - 7.1e-44 149.1 0.0 1.5e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KOS14260.1 - 5.7e-08 32.8 0.0 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KOS14260.1 - 1.6e-06 27.8 0.0 7.8e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS14260.1 - 4.3e-06 26.8 0.0 2.2e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KOS14260.1 - 7.6e-06 26.1 0.2 0.00042 20.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS14260.1 - 8e-05 23.4 0.0 0.00018 22.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS14260.1 - 8.4e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS14260.1 - 0.00011 21.9 0.0 0.00031 20.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KOS14260.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KOS14260.1 - 0.00089 18.0 0.0 0.0018 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KOS14260.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS14260.1 - 0.002 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS14260.1 - 0.0026 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 KOS14260.1 - 0.0034 16.6 0.0 0.077 12.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 KOS14260.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KOS14260.1 - 0.004 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KOS14260.1 - 0.0077 15.4 0.1 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KOS14260.1 - 0.0078 15.6 0.1 0.094 12.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KOS14260.1 - 0.0098 16.1 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KOS14260.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF2072 PF09845.4 KOS14260.1 - 0.019 14.9 0.2 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Parvo_NS1 PF01057.12 KOS14260.1 - 0.019 13.8 0.1 0.094 11.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KOS14260.1 - 0.02 14.3 0.1 0.094 12.1 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KOS14260.1 - 0.021 14.4 0.3 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KOS14260.1 - 0.023 14.3 0.0 0.59 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 KOS14260.1 - 0.026 13.4 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KOS14260.1 - 0.037 14.1 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KOS14260.1 - 0.06 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 KOS14260.1 - 0.08 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Neugrin PF06413.6 KOS14261.1 - 1.9e-11 44.2 0.3 3.1e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 Neugrin Oligomerisation PF02410.10 KOS14261.1 - 1.1e-08 34.9 0.0 2.9e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 Oligomerisation domain MRP-L20 PF12824.2 KOS14261.1 - 5.5e-06 26.4 2.9 1.4e-05 25.1 2.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_23 PF13384.1 KOS14261.1 - 0.069 12.8 0.7 0.45 10.2 0.0 2.6 2 1 1 3 3 3 0 Homeodomain-like domain Trehalase PF01204.13 KOS14262.1 - 1.6e-157 525.2 0.3 2.2e-157 524.8 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KOS14262.1 - 1.7e-11 43.2 0.1 2.8e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 KOS14262.1 - 0.09 12.6 0.0 2 8.3 0.0 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain SMC_N PF02463.14 KOS14263.1 - 5.7e-63 212.0 0.0 8.1e-63 211.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS14263.1 - 6.6e-29 100.3 0.8 3.5e-28 97.9 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KOS14263.1 - 6.3e-18 65.8 2.0 6.3e-18 65.8 1.4 4.1 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KOS14263.1 - 2.1e-12 47.6 0.0 6.3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KOS14263.1 - 2e-06 27.1 0.0 0.043 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KOS14263.1 - 0.0016 17.9 0.1 0.004 16.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS14263.1 - 1.5 9.1 0.0 1.5 9.1 0.0 5.7 5 3 0 5 5 5 0 ABC transporter Sel1 PF08238.7 KOS14264.1 - 1.2e-16 60.6 23.8 2.3e-05 24.8 0.1 9.4 10 0 0 10 10 10 6 Sel1 repeat Cation_efflux PF01545.16 KOS14265.1 - 2.2e-35 122.1 8.8 2.8e-35 121.7 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family SMN PF06003.7 KOS14266.1 - 0.00013 21.1 2.1 0.00013 21.1 1.4 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KOS14266.1 - 0.00054 19.7 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 KOS14266.1 - 0.0071 16.1 1.1 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Fis1_TPR_C PF14853.1 KOS14266.1 - 0.087 12.7 0.2 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4157 PF13699.1 KOS14266.1 - 0.53 10.4 0.1 0.53 10.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4157) FadA PF09403.5 KOS14266.1 - 2.4 8.2 11.3 1.1 9.2 0.7 2.2 2 0 0 2 2 2 0 Adhesion protein FadA DUF2361 PF10153.4 KOS14268.1 - 5e-21 75.0 7.8 7.9e-21 74.3 5.4 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Nop14 PF04147.7 KOS14268.1 - 0.086 10.7 15.3 0.1 10.4 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KOS14268.1 - 0.12 11.6 3.6 0.19 11.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 KOS14268.1 - 1.1 8.2 22.5 0.16 11.0 0.2 2.1 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.7 KOS14268.1 - 4.6 6.4 14.0 8.1 5.6 9.7 1.4 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KOS14268.1 - 8.5 5.2 13.3 13 4.7 9.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_1 PF00076.17 KOS14269.1 - 0.00045 19.7 0.0 0.00098 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14269.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribonuclease PF00545.15 KOS14272.1 - 2.7e-09 36.9 0.0 3.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ribonuclease DRIM PF07539.7 KOS14273.1 - 2.4e-31 108.0 0.0 9.5e-31 106.1 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KOS14273.1 - 1.8 8.8 8.3 3.8 7.8 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat MFS_1 PF07690.11 KOS14274.1 - 0.034 12.8 8.9 0.034 12.8 5.1 1.6 2 0 0 2 2 2 0 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 KOS14274.1 - 0.046 13.0 0.7 0.059 12.7 0.5 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Na_Ca_ex PF01699.19 KOS14274.1 - 0.95 9.0 5.5 2.3 7.7 2.0 2.4 1 1 1 2 2 2 0 Sodium/calcium exchanger protein Arginosuc_synth PF00764.14 KOS14275.1 - 1.8e-159 530.9 0.0 2.2e-159 530.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KOS14275.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KOS14275.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 KOS14275.1 - 0.095 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Ish1 PF10281.4 KOS14275.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Kelch_3 PF13415.1 KOS14276.1 - 1.4e-36 123.8 8.1 7.7e-09 35.4 0.1 8.2 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KOS14276.1 - 2e-36 123.4 13.1 1.5e-09 37.4 0.5 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS14276.1 - 5.4e-34 115.5 4.8 1.8e-07 30.9 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KOS14276.1 - 1.3e-26 91.6 5.8 1.4e-09 37.6 0.5 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KOS14276.1 - 4.4e-23 80.5 3.5 2e-08 33.6 0.3 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KOS14276.1 - 9.6e-22 75.8 9.5 9.1e-05 22.0 0.1 6.7 6 1 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KOS14276.1 - 0.019 13.6 0.3 7 5.2 0.0 3.6 4 1 1 5 5 5 0 Recombination activating protein 2 Pro-kuma_activ PF09286.6 KOS14277.1 - 2.3e-29 102.3 0.0 3.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KOS14277.1 - 1.1e-09 37.8 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TTL PF03133.10 KOS14278.1 - 1.2e-46 158.9 0.0 2.5e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KOS14278.1 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Metallophos PF00149.23 KOS14279.1 - 1.1e-41 142.4 0.1 1.4e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cu_amine_oxid PF01179.15 KOS14280.1 - 1.8e-163 544.1 0.0 2.2e-163 543.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KOS14280.1 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Peptidase_S8 PF00082.17 KOS14281.1 - 3.1e-08 33.1 0.0 3.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Subtilase family CMAS PF02353.15 KOS14282.1 - 1.8e-64 217.4 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KOS14282.1 - 2.5e-15 56.5 0.0 4.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS14282.1 - 2.2e-11 44.0 0.0 9.5e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14282.1 - 3.9e-08 33.5 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS14282.1 - 1.3e-07 31.6 0.0 4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14282.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS14282.1 - 3.5e-07 30.8 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14282.1 - 8.1e-07 29.4 0.0 1.7e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS14282.1 - 4.1e-06 26.2 0.0 6.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 KOS14282.1 - 0.00048 19.4 0.0 0.0031 16.8 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 KOS14282.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KOS14282.1 - 0.0055 15.8 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KOS14282.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FmrO PF07091.6 KOS14282.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 KOS14282.1 - 0.23 11.1 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRK PF00485.13 KOS14283.1 - 1.5e-51 174.7 0.0 2.1e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KOS14283.1 - 4.8e-43 146.7 0.0 2.1e-40 138.1 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 KOS14283.1 - 9.2e-08 32.4 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS14283.1 - 3.3e-05 24.7 0.0 6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KOS14283.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KOS14283.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS14283.1 - 0.016 14.3 0.1 0.042 12.9 0.0 1.6 1 1 1 2 2 2 0 Zeta toxin ABC_tran PF00005.22 KOS14284.1 - 3.8e-15 56.3 0.0 6.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS14284.1 - 5.9e-09 36.2 0.8 0.0014 18.6 0.3 2.6 2 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KOS14284.1 - 9.8e-06 24.8 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KOS14284.1 - 0.00029 20.2 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KOS14284.1 - 0.0016 17.7 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KOS14284.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS14284.1 - 0.0049 16.8 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KOS14284.1 - 0.0089 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS14284.1 - 0.013 16.3 0.2 0.027 15.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS14284.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain Arf PF00025.16 KOS14284.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_10 PF12846.2 KOS14284.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KOS14284.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS14284.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KOS14284.1 - 0.092 12.8 0.1 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS14284.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KOS14284.1 - 0.13 12.0 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KOS14284.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Y_phosphatase2 PF03162.8 KOS14285.1 - 9.3e-53 177.9 0.0 1.1e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KOS14285.1 - 1.5e-05 25.2 0.0 0.00027 21.2 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KOS14285.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS14285.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase OTU PF02338.14 KOS14286.1 - 2.5e-20 73.2 0.3 2.5e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KOS14286.1 - 5.5e-06 25.9 0.0 0.00024 20.5 0.0 2.2 1 1 0 1 1 1 1 Peptidase C65 Otubain Peptidase_M18 PF02127.10 KOS14287.1 - 2.9e-146 487.3 0.0 3.3e-146 487.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KOS14287.1 - 0.00099 17.9 0.1 0.015 14.1 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase NAD_Gly3P_dh_C PF07479.9 KOS14288.1 - 1.5e-48 164.2 0.0 2.7e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KOS14288.1 - 1.3e-44 151.7 0.1 1.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KOS14288.1 - 0.0012 19.2 0.2 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF1767 PF08585.7 KOS14289.1 - 5.9e-05 23.2 0.0 0.00033 20.8 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1767) DUF1764 PF08576.5 KOS14290.1 - 2.5e-18 66.6 13.0 6.4e-16 59.0 9.0 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Pol_alpha_B_N PF08418.5 KOS14290.1 - 0.053 13.0 9.8 0.059 12.9 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Senescence_reg PF04520.8 KOS14290.1 - 0.19 12.2 8.8 0.24 11.8 6.1 1.1 1 0 0 1 1 1 0 Senescence regulator Mucin PF01456.12 KOS14290.1 - 0.31 10.8 8.6 0.41 10.4 6.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SOBP PF15279.1 KOS14290.1 - 1.9 8.7 6.3 2.2 8.5 4.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 KOS14290.1 - 2.3 6.3 11.8 2.5 6.2 8.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 KOS14290.1 - 2.9 6.1 6.7 3 6.0 4.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF515 PF04415.7 KOS14290.1 - 3.1 5.9 7.1 3.4 5.8 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_viral_N PF00242.12 KOS14290.1 - 3.7 6.4 11.0 4.4 6.2 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 KOS14290.1 - 4 6.5 11.0 4.6 6.3 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.12 KOS14290.1 - 4.3 6.0 6.2 4.6 5.9 4.3 1.0 1 0 0 1 1 1 0 Presenilin ORC6 PF05460.8 KOS14290.1 - 4.7 6.2 10.8 5.1 6.1 7.5 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CS PF04969.11 KOS14291.1 - 0.00024 21.5 0.0 0.00092 19.7 0.0 2.0 1 1 0 1 1 1 1 CS domain AA_permease_2 PF13520.1 KOS14293.1 - 2.4e-73 247.0 37.6 2.4e-73 247.0 26.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KOS14293.1 - 1.4e-20 73.1 35.4 1.7e-20 72.8 24.0 1.4 1 1 0 1 1 1 1 Amino acid permease Homeobox PF00046.24 KOS14293.1 - 4.3e-13 48.6 0.1 9.4e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS14293.1 - 0.00047 19.8 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain polyprenyl_synt PF00348.12 KOS14294.1 - 1.3e-72 243.7 0.0 1.9e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CN_hydrolase PF00795.17 KOS14294.1 - 1.4e-25 89.7 0.0 2.8e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acyltransferase PF01553.16 KOS14295.1 - 1.1e-11 44.3 0.0 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase ICL PF00463.16 KOS14296.1 - 1.1e-196 654.0 0.0 1.3e-196 653.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KOS14296.1 - 1.6e-10 40.6 0.0 5.1e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase zf-ZPR1 PF03367.8 KOS14297.1 - 4.5e-103 341.2 1.5 1.2e-51 174.0 0.0 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 KOS14297.1 - 0.00062 19.4 3.5 0.51 10.0 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KOS14297.1 - 0.005 16.2 12.9 0.046 13.2 0.4 4.4 4 1 0 4 4 4 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 KOS14297.1 - 0.022 13.9 8.3 0.37 10.0 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KOS14297.1 - 0.28 11.0 9.3 3.5 7.5 0.5 3.4 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KOS14297.1 - 0.36 10.8 6.2 6.4 6.8 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain UPF0547 PF10571.4 KOS14297.1 - 3.1 7.5 9.3 9.9 5.9 0.0 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 NAD_binding_8 PF13450.1 KOS14298.1 - 2.4e-11 43.4 0.0 2.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KOS14298.1 - 0.0003 19.8 0.0 0.0003 19.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS14298.1 - 0.0014 18.5 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS14298.1 - 0.0032 17.2 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KOS14298.1 - 0.004 17.2 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS14298.1 - 0.0041 17.5 0.0 0.0049 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 KOS14298.1 - 0.0068 15.9 0.0 0.0073 15.8 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain FAD_binding_2 PF00890.19 KOS14298.1 - 0.0078 15.1 0.0 0.0078 15.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KOS14298.1 - 0.018 14.1 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Strep_67kDa_ant PF06100.6 KOS14298.1 - 0.074 11.4 0.0 0.074 11.4 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Lycopene_cycl PF05834.7 KOS14298.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KOS14298.1 - 0.15 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Dabb PF07876.7 KOS14299.1 - 4.7e-14 52.6 0.0 5.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Uteroglobin PF01099.12 KOS14299.1 - 0.23 11.3 0.7 0.33 10.7 0.1 1.5 2 0 0 2 2 2 0 Uteroglobin family DUF1399 PF07173.7 KOS14300.1 - 0.039 14.2 0.1 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) Amidohydro_3 PF07969.6 KOS14302.1 - 3.8e-31 108.7 0.0 1.4e-29 103.5 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KOS14302.1 - 1.6e-18 67.7 0.2 2e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KOS14302.1 - 0.0035 17.1 1.1 0.0064 16.2 0.1 2.0 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KOS14302.1 - 0.01 15.5 0.0 0.081 12.5 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase family Saccharop_dh PF03435.13 KOS14303.1 - 5e-21 75.1 1.0 8.2e-21 74.4 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KOS14303.1 - 0.0011 19.2 0.1 0.0043 17.3 0.1 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS14303.1 - 0.016 15.1 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KOS14303.1 - 0.024 13.8 0.5 0.041 13.1 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family PEN-2 PF10251.4 KOS14303.1 - 0.041 14.0 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase NAD_binding_10 PF13460.1 KOS14303.1 - 0.058 13.3 0.3 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 NADH(P)-binding ADH_N PF08240.7 KOS14304.1 - 8e-28 96.3 3.3 1.2e-27 95.7 0.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS14304.1 - 1.6e-25 89.1 0.2 5.4e-25 87.4 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KOS14304.1 - 5.5e-05 24.0 0.0 0.00012 23.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KOS14304.1 - 0.059 13.0 0.1 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Pyr_redox_3 PF13738.1 KOS14304.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Asp_decarbox PF02261.11 KOS14304.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartate decarboxylase RCC1 PF00415.13 KOS14305.1 - 1.9e-21 75.9 10.1 1.8e-05 24.8 0.2 6.2 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS14305.1 - 4.3e-13 48.4 22.8 2.4e-05 23.8 1.0 5.7 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 KOS14305.1 - 3.7e-11 42.5 3.6 6.7e-11 41.7 2.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KOS14305.1 - 0.018 14.3 0.4 0.052 12.8 0.3 1.8 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KOS14305.1 - 0.023 14.4 2.7 0.032 13.9 0.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 KOS14305.1 - 0.093 12.0 0.3 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RanBP PF00641.13 KOS14305.1 - 7.7 5.7 6.8 23 4.1 0.2 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others GatB_N PF02934.10 KOS14306.1 - 1.5e-103 345.6 0.0 1.9e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KOS14306.1 - 1.7e-26 92.6 0.0 2.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 GatB domain Arylsulfotran_2 PF14269.1 KOS14307.1 - 3.4e-33 115.0 2.8 4.8e-33 114.5 1.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KOS14307.1 - 3.2e-09 35.8 0.6 1.7e-08 33.3 0.4 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Med9 PF07544.8 KOS14308.1 - 0.00074 19.1 0.1 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF3635 PF12330.3 KOS14309.1 - 9.4e-14 51.2 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 KOS14309.1 - 0.014 14.5 0.0 0.058 12.5 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain APH PF01636.18 KOS14309.1 - 4.1 7.0 13.3 0.13 11.9 1.1 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.17 KOS14310.1 - 1.9e-06 27.4 0.0 3.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14310.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14310.1 - 0.0026 17.5 0.1 0.0083 15.9 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS14310.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 KOS14310.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.21 KOS14312.1 - 1.9e-28 97.0 74.1 5.6e-06 26.3 0.5 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS14312.1 - 1.2e-25 87.9 73.7 0.00013 22.0 0.6 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS14312.1 - 1.7e-20 72.1 47.0 2.2e-05 24.5 0.1 9.7 9 0 0 9 9 9 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 KOS14312.1 - 1e-08 34.7 19.9 0.00036 20.3 0.1 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS14312.1 - 7.3e-06 25.9 32.4 0.031 14.4 0.0 9.0 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding IBR PF01485.16 KOS14312.1 - 0.095 12.5 16.5 1.7 8.6 0.4 5.3 2 2 2 4 4 4 0 IBR domain RRN7 PF11781.3 KOS14312.1 - 0.98 8.9 9.4 3.6 7.1 0.1 4.1 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-LYAR PF08790.6 KOS14312.1 - 4.2 7.1 0.0 4.2 7.1 0.0 5.3 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger DUF2321 PF10083.4 KOS14312.1 - 4.6 6.7 5.4 1.3 8.4 0.1 2.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) adh_short PF00106.20 KOS14313.1 - 5.8e-23 81.6 0.3 9.7e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS14313.1 - 5.1e-07 29.5 0.1 7.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS14313.1 - 1.6e-06 28.3 0.1 3.8e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KOS14313.1 - 2.3e-05 24.2 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KOS14313.1 - 0.00014 20.8 0.1 0.00018 20.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 KOS14313.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 KOS14313.1 - 0.04 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4063 PF13272.1 KOS14313.1 - 0.043 13.6 0.8 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) F420_oxidored PF03807.12 KOS14313.1 - 0.045 14.1 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KOS14313.1 - 0.059 12.6 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Molybdopterin PF00384.17 KOS14314.1 - 1.5e-71 241.4 0.0 7.7e-70 235.7 0.0 2.6 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KOS14314.1 - 1.4e-17 62.5 0.1 4.1e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KOS14314.1 - 4.5e-17 61.6 0.0 1.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KOS14314.1 - 4.1e-15 55.6 0.0 9.4e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KOS14314.1 - 1.7e-09 37.2 0.3 4.5e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KOS14314.1 - 0.00011 21.9 0.1 0.0071 16.1 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-UDP PF14569.1 KOS14314.1 - 0.06 13.1 0.2 0.44 10.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger Fer4_18 PF13746.1 KOS14314.1 - 0.3 11.5 3.8 0.87 10.0 2.7 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain BING4CT PF08149.6 KOS14315.1 - 3.9e-37 125.6 0.0 2.9e-36 122.8 0.0 2.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 KOS14315.1 - 9.2e-07 28.5 0.0 0.00056 19.6 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KOS14315.1 - 5.9e-06 25.3 0.0 8.9e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region PUA PF01472.15 KOS14316.1 - 1.9e-16 59.5 0.0 2.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 PUA domain ADH_N PF08240.7 KOS14317.1 - 4.6e-26 90.7 4.0 4.6e-26 90.7 2.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS14317.1 - 6.9e-22 77.3 0.1 1.4e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS14317.1 - 1.6e-05 24.1 0.8 0.00035 19.7 0.4 2.3 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KOS14317.1 - 5.5e-05 24.0 0.0 9.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_nitro PF00148.14 KOS14317.1 - 0.09 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Cation_efflux PF01545.16 KOS14318.1 - 9e-18 64.3 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family Ferritin PF00210.19 KOS14318.1 - 0.046 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain PsaX PF08078.7 KOS14318.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PsaX family DNA_binding_1 PF01035.15 KOS14319.1 - 2.8e-23 81.4 0.0 3.8e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain WD40 PF00400.27 KOS14320.1 - 4.4e-39 130.9 8.5 3.9e-10 39.1 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat Peptidase_C12 PF01088.16 KOS14321.1 - 1.1e-54 184.9 0.0 1.2e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 V-SNARE_C PF12352.3 KOS14322.1 - 6.4e-17 61.3 4.7 1.8e-16 59.9 3.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KOS14322.1 - 6.8e-15 55.0 2.6 6.8e-15 55.0 1.8 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 KOS14322.1 - 0.0037 16.9 0.3 0.0037 16.9 0.2 1.8 2 1 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 KOS14322.1 - 0.0075 14.3 0.1 0.011 13.8 0.1 1.3 1 0 0 1 1 1 1 Fusion glycoprotein F0 MMPL PF03176.10 KOS14322.1 - 0.024 13.3 0.6 0.04 12.6 0.3 1.3 1 1 0 1 1 1 0 MMPL family Sigma_reg_N PF13800.1 KOS14322.1 - 0.057 13.4 3.2 0.093 12.7 2.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Leo1 PF04004.8 KOS14322.1 - 0.058 13.1 0.3 0.058 13.1 0.2 1.7 2 0 0 2 2 2 0 Leo1-like protein ODV-E18 PF10717.4 KOS14322.1 - 0.061 12.7 0.6 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2730 PF10805.3 KOS14322.1 - 0.061 13.0 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF912 PF06024.7 KOS14322.1 - 0.074 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF883 PF05957.8 KOS14322.1 - 0.35 11.2 12.8 0.37 11.2 0.5 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1640 PF07798.6 KOS14322.1 - 0.37 10.8 8.2 0.88 9.5 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Gluconate_2-dh3 PF13618.1 KOS14322.1 - 2.3 8.3 7.8 3.3 7.8 0.4 2.7 1 1 2 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 ABC_tran PF00005.22 KOS14323.1 - 3e-37 127.9 0.0 6.4e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KOS14323.1 - 1.3e-29 103.4 10.3 1.3e-29 103.4 7.2 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 KOS14323.1 - 1.4e-07 31.7 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KOS14323.1 - 2e-06 27.1 0.0 0.0003 20.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KOS14323.1 - 0.00015 21.7 0.4 0.00037 20.5 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KOS14323.1 - 0.00063 19.2 0.2 0.0026 17.2 0.1 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane_3 PF13748.1 KOS14323.1 - 0.0019 17.2 0.1 0.0053 15.8 0.1 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF258 PF03193.11 KOS14323.1 - 0.0047 16.1 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KOS14323.1 - 0.0056 16.8 0.2 0.034 14.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS14323.1 - 0.011 16.5 0.0 0.032 15.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PLAC8 PF04749.12 KOS14323.1 - 0.012 16.1 2.1 0.09 13.3 0.1 2.7 2 1 0 2 2 2 0 PLAC8 family AAA PF00004.24 KOS14323.1 - 0.014 15.6 0.0 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS14323.1 - 0.02 14.5 0.0 0.45 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KOS14323.1 - 0.03 13.0 0.0 0.056 12.1 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.1 KOS14323.1 - 0.045 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KOS14323.1 - 0.056 13.3 0.1 0.65 9.9 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KOS14323.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain DUF1253 PF06862.7 KOS14324.1 - 1.4e-152 508.2 0.0 1.6e-152 507.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) FAM220 PF15487.1 KOS14325.1 - 0.35 10.2 4.4 0.4 10.0 3.0 1.3 1 0 0 1 1 1 0 FAM220 family Arf PF00025.16 KOS14327.1 - 3.2e-17 62.3 0.0 1.9e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS14327.1 - 3.4e-05 23.0 0.0 4.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS14327.1 - 0.00037 19.3 0.0 0.035 12.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KOS14327.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KOS14327.1 - 0.0084 16.6 0.0 0.076 13.5 0.0 2.1 1 1 1 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KOS14327.1 - 0.014 15.5 0.0 0.051 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS14327.1 - 0.018 14.5 0.1 0.15 11.4 0.0 2.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KOS14327.1 - 0.081 12.3 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 KOS14327.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MIP-T3 PF10243.4 KOS14328.1 - 0.1 11.0 36.2 0.12 10.7 25.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 KOS14328.1 - 0.12 11.6 36.7 0.16 11.1 25.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAGP PF05507.6 KOS14328.1 - 0.36 10.6 2.8 0.71 9.6 1.9 1.5 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) RR_TM4-6 PF06459.7 KOS14328.1 - 1.7 8.4 22.4 2.3 8.0 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF936 PF06075.7 KOS14328.1 - 3.2 6.5 27.7 3.9 6.2 19.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Ycf1 PF05758.7 KOS14328.1 - 3.4 5.2 17.3 4.2 4.9 12.0 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 KOS14328.1 - 3.4 6.5 6.3 4.3 6.2 4.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 KOS14328.1 - 3.5 5.5 22.1 4.6 5.1 15.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 KOS14328.1 - 7.3 5.6 14.5 11 5.0 10.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Serinc PF03348.10 KOS14328.1 - 7.7 5.1 8.4 10 4.6 5.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF221 PF02714.10 KOS14329.1 - 1.3e-82 277.3 21.4 1.3e-82 277.3 14.8 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS14329.1 - 7e-35 119.9 5.3 7e-35 119.9 3.7 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KOS14329.1 - 4.7e-19 68.6 1.0 7.7e-19 68.0 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KOS14329.1 - 9.1e-12 44.7 0.4 2.6e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein GATA PF00320.22 KOS14330.1 - 2.4e-14 52.3 5.1 4.6e-14 51.4 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Phosphoesterase PF04185.9 KOS14331.1 - 4.8e-80 269.5 4.1 7.1e-80 269.0 2.8 1.2 1 0 0 1 1 1 1 Phosphoesterase family Amino_oxidase PF01593.19 KOS14332.1 - 3.2e-50 171.5 0.2 8.3e-50 170.1 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KOS14332.1 - 6e-10 39.0 0.2 1.2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KOS14332.1 - 7.6e-07 29.3 0.2 3.9e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS14332.1 - 2.1e-05 23.5 0.4 3.7e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS14332.1 - 3.3e-05 23.0 0.1 5.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KOS14332.1 - 5e-05 22.3 0.2 0.0054 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS14332.1 - 0.00011 22.5 0.2 0.00029 21.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS14332.1 - 0.0012 17.3 0.0 0.0046 15.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KOS14332.1 - 0.0013 18.6 0.1 0.0036 17.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KOS14332.1 - 0.0032 16.6 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KOS14332.1 - 0.048 13.4 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KOS14332.1 - 0.057 12.2 0.2 0.096 11.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KOS14332.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KOS14332.1 - 0.087 11.8 0.1 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PCI PF01399.22 KOS14333.1 - 8.6e-05 22.8 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 PCI domain Ten1_2 PF15490.1 KOS14334.1 - 4.5e-06 26.2 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit CAP_C PF08603.6 KOS14335.1 - 0.071 12.4 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Rot1 PF10681.4 KOS14336.1 - 2.5e-44 151.1 1.6 3.2e-44 150.8 1.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box-like PF12937.2 KOS14337.1 - 3.4e-05 23.4 0.7 0.00062 19.4 0.3 2.6 2 0 0 2 2 2 1 F-box-like RE_BstXI PF09552.5 KOS14337.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 BstXI restriction endonuclease HORMA PF02301.13 KOS14338.1 - 2.3e-19 69.7 0.0 3.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Cut8_N PF14482.1 KOS14338.1 - 0.1 12.5 1.8 0.35 10.9 1.2 1.9 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DUF1649 PF07855.7 KOS14338.1 - 0.19 11.3 0.2 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) SR-25 PF10500.4 KOS14338.1 - 0.73 9.2 6.4 1.1 8.6 4.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nodulin-like PF06813.8 KOS14339.1 - 2.2e-18 66.4 6.3 6.2e-18 64.9 4.4 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KOS14339.1 - 5.5e-17 61.5 22.9 1.4e-16 60.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpc4 PF05132.9 KOS14340.1 - 6e-27 94.1 1.6 1.5e-26 92.8 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 PC-Esterase PF13839.1 KOS14341.1 - 6.9e-06 26.0 0.0 1.8e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Acylphosphatase PF00708.13 KOS14342.1 - 1.5e-22 79.4 0.0 1.5e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Cluap1 PF10234.4 KOS14343.1 - 0.012 14.7 0.4 0.013 14.7 0.3 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF106 PF01956.11 KOS14343.1 - 0.15 11.6 0.2 0.17 11.4 0.1 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 TPR_11 PF13414.1 KOS14344.1 - 5.6e-25 86.7 5.5 6.4e-12 44.9 0.4 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KOS14344.1 - 4.1e-16 57.8 6.2 1.1e-07 31.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14344.1 - 4.1e-15 55.4 13.9 1.2e-05 25.1 0.2 3.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS14344.1 - 7.7e-15 53.7 0.9 0.0014 18.6 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS14344.1 - 3.4e-14 53.0 2.9 4.2e-07 30.4 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14344.1 - 4.6e-14 52.5 5.3 3.3e-07 30.5 0.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14344.1 - 7.5e-14 50.4 6.8 3.9e-07 29.4 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14344.1 - 6.1e-13 48.1 3.6 3.7e-06 27.1 0.1 4.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS14344.1 - 1e-10 40.5 10.9 0.0005 19.6 0.1 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14344.1 - 3.6e-08 33.3 3.1 0.00013 22.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14344.1 - 7.3e-05 22.2 4.1 1.3 9.0 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS14344.1 - 0.0001 22.0 1.8 0.013 15.3 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 KOS14344.1 - 0.0017 17.6 5.5 0.0041 16.3 3.8 1.6 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 KOS14344.1 - 0.0049 16.9 3.0 0.65 10.1 0.5 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 KOS14344.1 - 0.0052 17.3 1.7 11 6.8 0.0 3.9 3 0 0 3 3 3 0 Sel1 repeat MIT PF04212.13 KOS14344.1 - 0.0062 16.4 3.1 0.53 10.2 0.3 3.2 3 1 0 3 3 2 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 KOS14344.1 - 0.0071 16.4 4.4 0.074 13.1 0.4 3.1 2 1 2 4 4 3 1 Tetratricopeptide repeat RPN7 PF10602.4 KOS14344.1 - 0.012 15.0 0.5 1.3 8.3 0.0 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_5 PF12688.2 KOS14344.1 - 0.084 12.9 0.2 0.47 10.5 0.1 2.2 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_10 PF13374.1 KOS14344.1 - 0.18 11.7 3.3 8 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 KOS14344.1 - 6.9 6.7 15.3 11 6.0 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) p450 PF00067.17 KOS14345.1 - 8.3e-76 255.3 0.0 1.7e-75 254.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UAA PF08449.6 KOS14346.1 - 2.1e-64 217.3 10.6 1.9e-62 210.8 7.4 2.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KOS14346.1 - 5.8e-07 29.6 21.5 6.3e-06 26.2 3.9 3.8 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KOS14346.1 - 3.3e-05 22.9 3.4 0.011 14.5 0.3 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) Borrelia_P13 PF05628.7 KOS14346.1 - 0.0013 18.5 1.0 0.0056 16.4 0.6 2.1 2 0 0 2 2 2 1 Borrelia membrane protein P13 TPT PF03151.11 KOS14346.1 - 0.0023 17.5 8.5 0.0023 17.5 5.9 3.3 3 1 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 KOS14346.1 - 0.019 15.1 23.8 0.044 13.9 1.1 3.4 4 1 0 4 4 4 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 KOS14346.1 - 0.16 11.7 5.4 2.3 8.0 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Nuc_sug_transp PF04142.10 KOS14346.1 - 1.5 7.8 14.0 0.19 10.8 0.4 2.5 3 0 0 3 3 3 0 Nucleotide-sugar transporter dCMP_cyt_deam_1 PF00383.17 KOS14347.1 - 2.2e-07 30.4 0.2 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region PAP2 PF01569.16 KOS14347.1 - 8.6e-06 25.4 1.9 1.7e-05 24.5 1.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily APOBEC_N PF08210.6 KOS14347.1 - 0.00063 19.4 0.2 0.0017 18.0 0.1 1.7 2 0 0 2 2 2 1 APOBEC-like N-terminal domain SpoVAB PF13782.1 KOS14347.1 - 0.1 12.5 3.0 0.72 9.8 0.2 2.7 2 1 1 3 3 3 0 Stage V sporulation protein AB TPK_catalytic PF04263.11 KOS14348.1 - 5.3e-24 84.1 0.0 8.3e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KOS14348.1 - 6.5e-15 54.6 0.1 1e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUP PF06516.6 KOS14349.1 - 4.3e-103 344.4 0.2 6.7e-103 343.7 0.0 1.4 2 0 0 2 2 2 1 Purine nucleoside permease (NUP) NUDIX PF00293.23 KOS14349.1 - 1.5e-12 47.2 0.0 2.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Costars PF14705.1 KOS14349.1 - 0.097 12.6 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Costars Nop52 PF05997.7 KOS14350.1 - 1.4e-51 174.9 0.0 1.8e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MIF4G PF02854.14 KOS14351.1 - 2.6e-52 177.2 0.4 5.2e-52 176.3 0.2 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KOS14351.1 - 1.4e-17 63.2 0.2 4.9e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 KOS14351.1 - 3.5e-09 36.3 0.2 1.4e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 MA3 domain GIT_SHD PF08518.6 KOS14352.1 - 3.1e-22 77.5 8.6 4.4e-13 48.3 1.7 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TMF_DNA_bd PF12329.3 KOS14352.1 - 0.0077 16.0 3.9 0.0077 16.0 2.7 4.0 4 0 0 4 4 4 2 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 KOS14352.1 - 0.37 9.8 33.0 0.011 14.8 17.7 2.1 2 0 0 2 2 2 0 Tropomyosin DUF972 PF06156.8 KOS14352.1 - 1.7 9.0 21.7 2.7 8.3 1.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 KOS14352.1 - 3.8 7.3 25.1 6.8 6.5 2.3 3.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KOS14352.1 - 5.1 7.0 4.9 3.1 7.7 0.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 KOS14352.1 - 9.4 6.2 13.9 0.24 11.3 1.3 3.4 2 1 1 3 3 3 0 bZIP transcription factor Aldo_ket_red PF00248.16 KOS14353.1 - 5.7e-71 238.6 0.1 6.5e-71 238.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.2 KOS14354.1 - 2.3e-21 76.7 0.6 3e-21 76.3 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS14354.1 - 5.8e-14 52.0 0.0 1.2e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS14354.1 - 5.2e-09 35.9 0.0 1e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.9 KOS14354.1 - 0.00024 20.4 0.1 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FSH1 PF03959.8 KOS14354.1 - 0.00026 20.5 0.1 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KOS14354.1 - 0.00041 20.1 0.0 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KOS14354.1 - 0.00052 19.5 0.1 0.2 11.0 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KOS14354.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KOS14354.1 - 0.0015 18.1 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 KOS14354.1 - 0.13 11.5 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family NUC153 PF08159.7 KOS14355.1 - 1.1e-09 37.6 0.1 1.1e-09 37.6 0.1 3.5 3 0 0 3 3 3 2 NUC153 domain bZIP_1 PF00170.16 KOS14356.1 - 9.2e-07 28.7 4.0 2.8e-06 27.1 1.4 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KOS14356.1 - 0.11 12.7 2.8 1.9 8.8 0.1 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.10 KOS14356.1 - 0.19 11.5 7.3 0.28 11.0 2.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Cwf_Cwc_15 PF04889.7 KOS14357.1 - 0.54 9.9 5.5 0.067 12.8 0.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Med5 PF08689.5 KOS14358.1 - 2.8e-08 31.9 0.0 5e-08 31.1 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit Med5 SapB_2 PF03489.12 KOS14358.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 2 LRR_4 PF12799.2 KOS14359.1 - 3.5e-11 42.4 1.3 6.3e-09 35.2 0.3 2.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS14359.1 - 1.1e-09 37.8 1.5 2.8e-09 36.5 1.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KOS14359.1 - 2.2e-07 29.9 1.2 0.45 10.7 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KOS14359.1 - 0.00016 21.2 7.5 1.2 9.6 0.0 4.4 4 0 0 4 4 4 2 Leucine rich repeat Kri1 PF05178.7 KOS14360.1 - 1.8e-24 85.9 12.8 1.8e-24 85.9 8.9 4.9 3 2 0 4 4 4 1 KRI1-like family Kri1_C PF12936.2 KOS14360.1 - 3.4e-18 65.3 0.1 3.4e-18 65.3 0.1 4.0 4 0 0 4 4 4 1 KRI1-like family C-terminal 4HBT PF03061.17 KOS14361.1 - 1.9e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KOS14361.1 - 0.017 15.1 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF4227 PF14004.1 KOS14362.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4227) Apc5 PF12862.2 KOS14365.1 - 4.8e-12 45.5 0.5 4.8e-12 45.5 0.4 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 KOS14365.1 - 3.4e-05 23.8 3.5 0.0053 16.8 0.1 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NYN_YacP PF05991.6 KOS14365.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 YacP-like NYN domain TPR_11 PF13414.1 KOS14365.1 - 0.54 9.9 11.5 0.27 10.9 0.2 4.1 4 0 0 4 4 4 0 TPR repeat PPR_2 PF13041.1 KOS14366.1 - 3.8e-27 93.9 0.3 1.8e-07 31.0 0.0 8.5 8 1 2 10 10 10 4 PPR repeat family PPR PF01535.15 KOS14366.1 - 2.2e-15 55.4 2.4 0.042 13.8 0.0 8.2 9 0 0 9 9 9 4 PPR repeat PPR_3 PF13812.1 KOS14366.1 - 4.3e-13 48.4 26.2 0.019 15.2 0.0 10.6 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 KOS14366.1 - 7.8e-13 47.6 7.2 0.0025 17.2 0.0 7.0 9 0 0 9 9 9 4 PPR repeat NAP PF00956.13 KOS14367.1 - 2.9e-30 105.1 18.6 1.9e-28 99.2 12.9 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 KOS14367.1 - 0.55 9.2 16.4 0.78 8.7 11.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 KOS14367.1 - 1.7 6.5 12.1 2.6 5.9 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 KOS14367.1 - 3.2 6.6 6.1 3.9 6.4 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PTRF_SDPR PF15237.1 KOS14367.1 - 3.7 6.8 7.5 40 3.5 4.1 2.3 2 0 0 2 2 2 0 PTRF/SDPR family CENP-B_dimeris PF09026.5 KOS14367.1 - 9.5 6.5 32.5 12 6.1 1.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BMF PF15185.1 KOS14367.1 - 9.6 5.4 12.1 2.9 7.1 6.1 1.7 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis Yae1_N PF09811.4 KOS14368.1 - 1.3e-05 24.5 4.7 2.9e-05 23.5 3.3 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 KOS14368.1 - 0.026 14.1 0.1 0.58 9.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 KOS14369.1 - 0.006 16.9 1.6 0.006 16.9 1.1 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein UBN_AB PF14075.1 KOS14369.1 - 0.031 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Dus PF01207.12 KOS14370.1 - 2.5e-46 157.9 0.0 4e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ribosomal_L1 PF00687.16 KOS14372.1 - 1.4e-21 76.8 0.0 1.2e-20 73.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Toprim_3 PF13362.1 KOS14372.1 - 0.012 15.8 0.0 0.071 13.3 0.0 2.2 3 0 0 3 3 3 0 Toprim domain Lactamase_B_2 PF12706.2 KOS14373.1 - 8.3e-29 100.5 0.7 1.3e-28 99.9 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KOS14373.1 - 4.9e-06 26.3 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS14373.1 - 0.19 11.3 4.8 0.23 11.1 1.4 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily SSB PF00436.20 KOS14374.1 - 5.9e-14 51.7 0.0 7.4e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Thioredoxin PF00085.15 KOS14375.1 - 1.1e-33 115.0 0.3 1.2e-33 114.8 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS14375.1 - 1.4e-10 41.3 0.2 5.7e-10 39.3 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS14375.1 - 4.5e-08 33.1 0.0 2.4e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KOS14375.1 - 3.5e-06 26.6 0.5 0.00018 21.0 0.2 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KOS14375.1 - 1.3e-05 24.7 0.1 1.5e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KOS14375.1 - 3.4e-05 23.5 0.2 5.7e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 KOS14375.1 - 3.7e-05 23.2 0.1 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.1 KOS14375.1 - 0.00013 21.8 0.1 0.00018 21.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 KOS14375.1 - 0.0072 15.8 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Calsequestrin PF01216.12 KOS14375.1 - 0.015 14.0 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin Glutaredoxin PF00462.19 KOS14375.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_6 PF13848.1 KOS14375.1 - 0.04 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_5 PF13743.1 KOS14375.1 - 0.097 12.2 0.1 0.2 11.2 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.15 KOS14375.1 - 0.16 11.5 1.3 0.22 11.0 0.1 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain RhoGEF PF00621.15 KOS14376.1 - 1.1e-30 106.8 0.0 1.8e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain Urm1 PF09138.6 KOS14377.1 - 1.5e-34 117.9 0.0 1.7e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KOS14377.1 - 8.9e-05 22.8 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family TrkA_C PF02080.16 KOS14377.1 - 0.14 11.7 0.1 0.51 9.9 0.0 2.0 1 1 1 2 2 2 0 TrkA-C domain zf-U1 PF06220.7 KOS14378.1 - 3.3e-18 64.9 6.5 4.3e-18 64.5 4.5 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KOS14378.1 - 0.51 10.5 4.1 0.83 9.8 2.8 1.4 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Lung_7-TM_R PF06814.8 KOS14379.1 - 1.6e-53 181.5 24.4 6.1e-53 179.6 16.9 1.8 1 1 0 1 1 1 1 Lung seven transmembrane receptor UCH PF00443.24 KOS14380.1 - 3e-30 105.2 0.0 3.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KOS14380.1 - 9.7e-13 48.0 0.4 1.9e-12 47.0 0.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KOS14380.1 - 0.029 13.8 0.0 0.03 13.7 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Aminotran_3 PF00202.16 KOS14381.1 - 8.8e-84 281.2 0.0 1.2e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ASL_C2 PF14698.1 KOS14381.1 - 0.1 12.6 0.8 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Argininosuccinate lyase C-terminal WD40 PF00400.27 KOS14382.1 - 9.1e-61 199.7 18.7 1.2e-10 40.8 0.0 8.0 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS14382.1 - 0.09 10.8 7.8 2.3 6.2 0.1 3.9 1 1 3 4 4 4 0 Nucleoporin Nup120/160 FAD-oxidase_C PF02913.14 KOS14383.1 - 3.7e-58 196.7 0.0 6.4e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KOS14383.1 - 1.7e-37 128.0 0.2 3.2e-37 127.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.22 KOS14384.1 - 2.1e-65 216.4 6.7 4.7e-21 74.3 0.1 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DNA_pol_B_thumb PF14791.1 KOS14385.1 - 3.2e-18 65.1 0.0 6.6e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KOS14385.1 - 9e-14 51.4 0.0 1.8e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KOS14385.1 - 3.7e-13 49.4 0.0 1.7e-11 44.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KOS14385.1 - 3.9e-09 35.9 0.0 6.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KOS14385.1 - 0.00011 22.3 0.0 0.078 13.1 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KOS14385.1 - 0.00048 20.3 0.0 0.00098 19.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH PF00633.18 KOS14385.1 - 0.00065 19.2 0.1 0.073 12.8 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_2 PF12826.2 KOS14385.1 - 0.00067 19.4 0.0 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.3 KOS14385.1 - 0.091 12.6 0.0 2.2 8.2 0.0 2.4 1 1 1 2 2 2 0 Pathogenicity locus DcpS_C PF11969.3 KOS14386.1 - 3.5e-13 49.7 0.0 6.8e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KOS14386.1 - 9.2e-10 38.9 0.2 2.3e-05 24.8 0.1 2.3 2 0 0 2 2 2 2 HIT domain PH PF00169.24 KOS14387.1 - 7.7e-29 99.9 0.1 2.5e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KOS14387.1 - 9.8e-13 48.3 7.8 0.00019 21.6 1.5 3.8 3 1 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.1 KOS14387.1 - 1.6e-06 28.0 5.3 0.00083 19.3 0.4 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KOS14387.1 - 4.5e-06 26.4 2.3 0.1 12.4 0.0 3.2 3 0 0 3 3 3 3 PH domain Mcp5_PH PF12814.2 KOS14387.1 - 1.3e-05 25.0 5.0 0.12 12.3 1.1 3.3 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 KOS14387.1 - 0.0029 17.7 3.4 1.4 9.0 0.8 3.7 2 2 1 3 3 3 2 Pleckstrin homology domain Ribosomal_L22 PF00237.14 KOS14388.1 - 1.5e-20 73.0 0.1 2.3e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAD_binding_8 PF08022.7 KOS14389.1 - 3.1e-17 62.3 0.1 5.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KOS14389.1 - 4.9e-12 46.0 0.0 2.8e-07 30.5 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KOS14389.1 - 0.0002 21.4 1.8 0.0002 21.4 1.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KOS14389.1 - 0.015 15.4 0.0 0.055 13.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Cellulase PF00150.13 KOS14390.1 - 6.7e-13 48.4 11.1 1.7e-12 47.1 7.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GIDA PF01134.17 KOS14391.1 - 6.8e-127 423.5 0.0 1.6e-126 422.3 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KOS14391.1 - 1.4e-16 60.2 0.0 3.5e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 KOS14391.1 - 3.1e-05 23.2 1.5 8.2e-05 21.8 0.9 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS14391.1 - 3.7e-05 23.7 0.2 9.6e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS14391.1 - 0.00068 18.6 2.2 0.43 9.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS14391.1 - 0.014 14.2 3.9 0.034 12.9 2.7 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KOS14391.1 - 0.015 15.6 0.5 0.036 14.4 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KOS14391.1 - 0.035 13.6 0.6 0.06 12.9 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KOS14391.1 - 0.11 12.2 1.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KOS14391.1 - 0.45 8.9 3.6 0.28 9.5 1.3 1.5 2 0 0 2 2 2 0 HI0933-like protein RNase_T PF00929.19 KOS14392.1 - 1.6e-18 67.5 0.0 2.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease GalP_UDP_tr_C PF02744.12 KOS14392.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF2026 PF09641.5 KOS14392.1 - 0.13 11.6 0.0 0.51 9.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2026) FKBP_C PF00254.23 KOS14393.1 - 4.6e-32 109.8 0.0 5.8e-32 109.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_31 PF01055.21 KOS14396.1 - 2e-127 425.7 1.7 2.9e-127 425.1 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KOS14396.1 - 2e-19 69.1 0.0 5.3e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like T2SJ PF11612.3 KOS14396.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J CRAL_TRIO_2 PF13716.1 KOS14396.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Myb_Cef PF11831.3 KOS14397.1 - 4.3e-40 137.3 0.0 4.3e-40 137.3 0.0 4.0 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KOS14397.1 - 2.2e-21 75.6 4.4 1.1e-11 44.5 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS14397.1 - 7.8e-20 70.7 7.3 5.4e-14 52.0 1.9 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain UPF0016 PF01169.14 KOS14398.1 - 7.7e-40 134.9 19.2 4.1e-21 74.9 1.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 KOS14398.1 - 2e-05 24.1 4.8 0.0085 15.5 0.0 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE TerC PF03741.11 KOS14398.1 - 0.00071 19.0 5.4 0.0071 15.8 0.0 2.3 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF4131 PF13567.1 KOS14398.1 - 0.059 12.7 7.8 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YtpI PF14007.1 KOS14398.1 - 0.12 12.3 0.3 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 YtpI-like protein LysE PF01810.13 KOS14398.1 - 0.18 11.0 13.6 0.8 8.9 2.9 2.2 2 0 0 2 2 2 0 LysE type translocator DUF204 PF02659.10 KOS14398.1 - 1.2 9.2 13.7 4.9 7.3 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF NAPRTase PF04095.11 KOS14399.1 - 8.8e-53 179.0 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Peptidase_M20 PF01546.23 KOS14400.1 - 3.2e-31 108.3 0.0 5.1e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS14400.1 - 2e-14 53.2 0.0 3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KOS14400.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF1207 PF06727.6 KOS14400.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) CDP-OH_P_transf PF01066.16 KOS14401.1 - 9.1e-12 45.1 2.7 9.1e-12 45.1 1.9 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.22 KOS14402.1 - 1.6e-56 187.9 3.1 6.7e-20 70.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 KOS14403.1 - 7.9e-52 175.5 0.2 7.9e-52 175.5 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KOS14403.1 - 5.5e-35 121.7 3.3 5.5e-35 121.7 2.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KOS14403.1 - 2.9e-27 94.5 0.3 4.6e-13 49.1 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KOS14403.1 - 1.6e-12 48.0 0.0 2.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS14403.1 - 0.043 13.3 0.2 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Clat_adaptor_s PF01217.15 KOS14404.1 - 3.3e-52 175.9 1.1 3.7e-52 175.8 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pro_isomerase PF00160.16 KOS14405.1 - 5.5e-41 140.3 0.0 8.6e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KOS14405.1 - 1.8e-07 30.6 0.2 5.2e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger Herpes_capsid PF06112.6 KOS14405.1 - 0.23 11.4 5.5 0.14 12.2 1.9 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SOBP PF15279.1 KOS14405.1 - 2.3 8.5 5.9 0.59 10.4 1.3 1.8 1 1 0 2 2 2 0 Sine oculis-binding protein NADH-u_ox-rdase PF10785.4 KOS14406.1 - 1.2e-31 108.7 0.2 1.6e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KOS14406.1 - 3.1e-15 55.6 0.0 4.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Ribosomal_L12 PF00542.14 KOS14407.1 - 3.3e-20 71.8 10.0 3.1e-19 68.7 4.8 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PBP_dimer PF03717.10 KOS14407.1 - 0.029 14.4 0.4 0.034 14.2 0.3 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF2765 PF10963.3 KOS14407.1 - 0.054 13.4 0.5 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) DUF4349 PF14257.1 KOS14407.1 - 1.5 8.0 7.2 5 6.2 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) ATP12 PF07542.6 KOS14408.1 - 6.7e-40 135.8 0.1 1.3e-39 134.9 0.1 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein LEAP-2 PF07359.6 KOS14408.1 - 0.043 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) SnoaL_3 PF13474.1 KOS14408.1 - 0.095 12.7 0.4 18 5.4 0.0 3.1 2 1 1 3 3 3 0 SnoaL-like domain Metallophos PF00149.23 KOS14409.1 - 2.2e-43 147.9 0.3 2.8e-43 147.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS14409.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RecR PF02132.10 KOS14409.1 - 0.073 12.5 0.2 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 RecR protein MFS_1 PF07690.11 KOS14410.1 - 3e-39 134.7 26.3 3e-39 134.7 18.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS14410.1 - 1.7e-13 49.9 17.6 3e-13 49.1 12.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter PP2C PF00481.16 KOS14411.1 - 2.9e-32 112.0 0.0 3.3e-30 105.3 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C RRM_1 PF00076.17 KOS14411.1 - 2.2e-15 56.0 0.0 4.6e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14411.1 - 4.8e-07 29.6 0.0 1e-05 25.4 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14411.1 - 3.1e-06 26.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IFT43 PF15305.1 KOS14411.1 - 2.9 7.9 8.1 0.088 12.8 0.3 2.2 2 0 0 2 2 2 0 Intraflagellar transport protein 43 Methyltransf_11 PF08241.7 KOS14412.1 - 5.5e-09 36.3 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS14412.1 - 1.1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14412.1 - 5e-06 26.9 0.1 9.1e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14412.1 - 3.7e-05 23.3 0.0 0.005 16.4 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS14412.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 KOS14412.1 - 0.08 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 KOS14412.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PTS_2-RNA PF01885.11 KOS14413.1 - 2.4e-51 173.7 0.0 3.3e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RabGAP-TBC PF00566.13 KOS14414.1 - 6.5e-46 156.4 0.0 8.5e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TrmE_N PF10396.4 KOS14415.1 - 5.1e-32 110.2 0.0 1.7e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KOS14415.1 - 1e-18 67.5 0.9 4e-18 65.6 0.1 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KOS14415.1 - 3e-18 65.8 0.0 5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS14415.1 - 1.7e-07 30.6 0.0 2.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KOS14415.1 - 6.4e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KOS14415.1 - 0.00032 21.1 0.0 0.00061 20.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KOS14415.1 - 0.0076 15.4 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KOS14415.1 - 0.0099 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 KOS14415.1 - 0.048 13.0 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 KOS14415.1 - 0.054 13.4 0.4 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS14415.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase GTP_EFTU PF00009.22 KOS14415.1 - 0.1 12.0 0.0 5.3 6.4 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KOS14415.1 - 0.16 12.1 0.1 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.16 KOS14416.1 - 9.1e-70 234.6 0.1 1e-69 234.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 KOS14416.1 - 0.074 12.9 2.9 0.4 10.6 0.0 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family CGI-121 PF08617.5 KOS14417.1 - 2.2e-30 105.4 0.0 4.3e-30 104.5 0.0 1.4 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Pescadillo_N PF06732.6 KOS14418.1 - 7.2e-119 396.2 0.5 7.2e-119 396.2 0.3 2.0 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 KOS14418.1 - 0.00062 19.8 0.0 0.0023 18.0 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MTP18 PF10558.4 KOS14419.1 - 2.1e-52 176.9 0.4 3.5e-52 176.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ACPS PF01648.15 KOS14419.1 - 9.8e-18 64.0 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Carb_kinase PF01256.12 KOS14420.1 - 7.1e-54 182.6 0.0 8.5e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Ras PF00071.17 KOS14421.1 - 2.2e-54 183.2 0.0 2.5e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS14421.1 - 1e-16 61.5 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS14421.1 - 2.3e-08 33.4 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS14421.1 - 0.0011 18.3 0.0 0.01 15.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.1 KOS14421.1 - 0.09 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ubie_methyltran PF01209.13 KOS14422.1 - 1e-70 237.4 0.3 2.5e-37 128.2 0.0 2.3 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KOS14422.1 - 7.8e-10 39.1 0.0 3.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14422.1 - 2.7e-09 36.8 0.0 0.0003 20.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14422.1 - 6.4e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS14422.1 - 2.1e-07 30.8 0.0 3.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14422.1 - 5.1e-07 30.0 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS14422.1 - 3.4e-06 27.5 0.0 6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS14422.1 - 0.0002 21.4 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KOS14422.1 - 0.0091 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Complex1_LYR PF05347.10 KOS14423.1 - 1.1e-11 44.3 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS14423.1 - 1.6e-10 41.0 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KOS14423.1 - 4.5e-06 27.0 0.0 5.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like S1-P1_nuclease PF02265.11 KOS14424.1 - 1.2e-48 165.9 1.2 1.2e-47 162.7 0.8 2.4 1 1 0 1 1 1 1 S1/P1 Nuclease OST3_OST6 PF04756.8 KOS14425.1 - 1.1e-20 73.7 4.0 1.1e-20 73.7 2.8 1.5 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 KOS14425.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF3094 PF11293.3 KOS14425.1 - 6 6.4 7.7 71 2.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) Sugar_tr PF00083.19 KOS14426.1 - 2.5e-213 708.6 48.9 1.4e-111 373.2 17.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS14426.1 - 1.5e-47 162.0 86.3 2.8e-23 82.1 19.9 4.1 2 2 2 4 4 4 4 Major Facilitator Superfamily WASH-7_mid PF14744.1 KOS14426.1 - 0.058 12.2 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 TB2_DP1_HVA22 PF03134.14 KOS14426.1 - 0.21 11.3 5.3 0.053 13.2 0.6 2.3 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GARS_A PF01071.14 KOS14427.1 - 1.1e-73 246.9 0.0 1.6e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KOS14427.1 - 2.4e-33 114.5 0.0 6.5e-33 113.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KOS14427.1 - 9.2e-30 103.6 0.0 1.9e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KOS14427.1 - 7.4e-29 99.7 0.4 1.4e-27 95.7 0.1 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KOS14427.1 - 3.6e-19 68.7 2.0 2.2e-18 66.2 0.3 2.9 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 KOS14427.1 - 1.5e-07 30.4 0.0 2.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KOS14427.1 - 8.3e-06 25.6 0.0 4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KOS14427.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KOS14427.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Chorismate_bind PF00425.13 KOS14428.1 - 1.5e-75 253.8 0.0 1.9e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Homeobox_KN PF05920.6 KOS14429.1 - 1.2e-13 50.5 1.1 1.2e-13 50.5 0.8 2.2 2 1 0 2 2 2 1 Homeobox KN domain Ustilago_mating PF05722.7 KOS14429.1 - 0.00027 20.3 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Tctex-1 PF03645.8 KOS14429.1 - 0.034 13.9 0.1 0.76 9.6 0.0 2.7 3 0 0 3 3 3 0 Tctex-1 family Spc97_Spc98 PF04130.8 KOS14429.1 - 0.081 11.2 0.9 0.11 10.7 0.6 1.1 1 0 0 1 1 1 0 Spc97 / Spc98 family Sas10_Utp3 PF04000.10 KOS14430.1 - 1.2e-10 41.4 2.2 2.6e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CHASE3 PF05227.8 KOS14430.1 - 0.096 12.3 0.2 0.36 10.5 0.0 2.0 1 1 1 2 2 2 0 CHASE3 domain Hep_59 PF07052.6 KOS14431.1 - 9.3e-07 29.1 0.1 5.1e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Aldo_ket_red PF00248.16 KOS14432.1 - 1.8e-14 53.2 0.0 9.3e-08 31.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Hexapep PF00132.19 KOS14433.1 - 8.3e-08 31.3 7.5 0.0006 19.1 0.1 4.4 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KOS14433.1 - 0.06 12.9 5.3 0.089 12.3 0.5 3.0 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase PAXNEB PF05625.6 KOS14434.1 - 1.6e-36 125.9 0.0 2.1e-24 86.0 0.0 3.1 3 0 0 3 3 3 3 PAXNEB protein CDH PF02611.10 KOS14435.1 - 0.041 13.1 0.1 0.07 12.3 0.1 1.3 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DUF1616 PF07760.6 KOS14435.1 - 0.49 9.4 3.0 1.6 7.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Mon1 PF03164.9 KOS14436.1 - 6.4e-41 140.3 0.0 9e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 MAP65_ASE1 PF03999.7 KOS14437.1 - 0.14 10.7 3.9 0.19 10.2 2.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ADH_N PF08240.7 KOS14438.1 - 5.9e-25 87.1 1.5 1.5e-24 85.8 1.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS14438.1 - 8.6e-16 57.6 0.0 1.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KOS14438.1 - 4.8e-05 22.5 0.0 7.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KOS14438.1 - 0.00028 20.9 0.0 0.00064 19.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KOS14438.1 - 0.00031 20.5 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KOS14438.1 - 0.00079 19.2 0.2 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 KOS14438.1 - 0.0058 16.0 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KOS14438.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KOS14438.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 KOS14438.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 KOS14438.1 - 0.043 12.8 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KOS14438.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 KOS14438.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KOS14438.1 - 0.15 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DASH_Dam1 PF08653.5 KOS14439.1 - 1.9e-20 72.3 0.2 2.9e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 RPA_C PF08784.6 KOS14439.1 - 0.02 15.2 1.6 0.033 14.5 0.1 2.3 2 1 0 2 2 2 0 Replication protein A C terminal MADF_DNA_bdg PF10545.4 KOS14440.1 - 0.00065 19.8 1.2 0.0049 17.0 0.3 2.7 2 2 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like FliJ PF02050.11 KOS14440.1 - 0.064 13.3 1.9 0.11 12.5 1.3 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein BicD PF09730.4 KOS14440.1 - 0.12 10.6 0.7 0.17 10.1 0.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D WXG100 PF06013.7 KOS14440.1 - 0.21 11.5 3.1 6.7 6.7 0.7 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG PilJ PF13675.1 KOS14440.1 - 0.3 11.4 6.5 0.7 10.2 2.6 2.9 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Complex1_LYR PF05347.10 KOS14440.1 - 0.33 10.7 7.0 0.17 11.6 0.5 2.6 2 1 0 2 2 2 0 Complex 1 protein (LYR family) DUF3886 PF13025.1 KOS14440.1 - 2.1 8.3 4.6 0.9 9.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) G-patch PF01585.18 KOS14441.1 - 8e-12 44.7 1.9 2.3e-11 43.2 1.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KOS14441.1 - 0.0001 22.0 1.3 0.0001 22.0 0.9 3.5 2 1 0 2 2 1 1 DExH-box splicing factor binding site SR-25 PF10500.4 KOS14441.1 - 0.00016 21.1 23.2 0.00032 20.2 16.1 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TATR PF03430.8 KOS14441.1 - 0.00042 19.0 14.6 0.00049 18.8 10.1 1.1 1 0 0 1 1 1 1 Trans-activating transcriptional regulator CDC45 PF02724.9 KOS14441.1 - 0.03 12.3 15.9 0.038 12.0 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KOS14441.1 - 0.035 14.0 14.3 0.05 13.5 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.2 KOS14441.1 - 0.054 13.6 15.7 0.091 12.9 10.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MIP-T3 PF10243.4 KOS14441.1 - 0.078 11.4 25.6 0.11 10.9 17.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 KOS14441.1 - 0.15 12.1 25.5 0.069 13.1 16.2 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 KOS14441.1 - 0.15 11.3 25.2 0.32 10.3 17.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Serinc PF03348.10 KOS14441.1 - 0.21 10.2 2.1 0.25 10.0 1.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glyco_transf_15 PF01793.11 KOS14441.1 - 0.42 9.4 11.2 0.59 9.0 7.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2413 PF10310.4 KOS14441.1 - 0.5 9.1 20.1 0.85 8.3 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_polI_A34 PF08208.6 KOS14441.1 - 0.76 9.4 34.1 1.4 8.5 23.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.7 KOS14441.1 - 1.2 8.3 22.1 2.1 7.4 15.3 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Parvo_coat PF00740.13 KOS14441.1 - 1.2 7.9 7.7 1.8 7.3 5.3 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2058 PF09831.4 KOS14441.1 - 2.9 7.7 24.1 5.6 6.8 16.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Zip PF02535.17 KOS14441.1 - 3.2 6.6 4.6 4.2 6.2 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 KOS14441.1 - 3.3 7.1 21.0 5.8 6.3 14.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NAM-associated PF14303.1 KOS14441.1 - 3.5 7.9 33.3 11 6.3 23.1 1.9 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain NARP1 PF12569.3 KOS14441.1 - 6.8 5.3 19.4 9.6 4.8 13.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 KOS14441.1 - 9.3 5.5 18.2 16 4.7 12.6 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 UreF PF01730.11 KOS14442.1 - 2e-07 31.2 0.8 3.1e-07 30.5 0.6 1.3 1 0 0 1 1 1 1 UreF SLS PF14611.1 KOS14443.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Peptidase_C25_C PF03785.9 KOS14443.1 - 0.024 14.4 0.2 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain TPR_11 PF13414.1 KOS14444.1 - 2.9e-22 78.0 14.8 1.5e-11 43.7 0.1 3.9 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KOS14444.1 - 3.4e-22 77.0 0.8 1.2e-06 27.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14444.1 - 7e-19 66.1 12.2 5.7e-05 22.7 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS14444.1 - 7.3e-16 56.6 0.1 0.0028 17.2 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS14444.1 - 2.5e-12 45.9 5.6 5.6e-05 23.0 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14444.1 - 1.1e-11 44.3 13.2 0.0053 17.2 0.1 6.5 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14444.1 - 1.6e-10 40.7 11.4 0.002 18.0 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS14444.1 - 1.5e-09 38.2 25.0 5.3e-07 30.1 0.0 5.6 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14444.1 - 1.3e-07 31.7 13.4 0.057 13.7 0.1 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.1 KOS14444.1 - 5.4e-07 29.6 7.2 0.0015 18.6 0.2 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14444.1 - 1.4e-06 27.6 2.7 1.2 9.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14444.1 - 3.1e-05 24.1 2.1 1.8 9.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS14444.1 - 0.0004 20.4 5.3 0.28 11.3 0.1 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 KOS14444.1 - 0.00065 18.9 0.9 0.97 8.5 0.0 2.6 2 1 0 2 2 2 2 Coatomer epsilon subunit FTCD_C PF04961.7 KOS14444.1 - 0.12 11.7 4.7 0.24 10.7 0.8 2.7 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase TPR_9 PF13371.1 KOS14444.1 - 0.37 10.6 7.7 1.7 8.5 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat PIG-S PF10510.4 KOS14445.1 - 2.6e-97 326.6 2.3 2.7e-86 290.3 0.1 2.2 1 1 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Trypan_PARP PF05887.6 KOS14445.1 - 5.8 6.7 10.8 11 5.8 7.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) K_oxygenase PF13434.1 KOS14446.1 - 1.1e-08 34.4 0.0 2.3e-05 23.4 0.0 2.9 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KOS14446.1 - 0.00048 20.2 0.1 0.39 10.7 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase BPL_C PF02237.12 KOS14446.1 - 0.027 14.1 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain XPG_I PF00867.13 KOS14447.1 - 4e-18 65.2 0.0 7.6e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KOS14447.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PolyA_pol PF01743.15 KOS14448.1 - 3.2e-22 79.0 0.0 6.5e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KOS14448.1 - 2.5e-06 26.9 0.0 0.00012 21.5 0.0 2.5 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A SIP1 PF04938.7 KOS14449.1 - 1.2e-22 80.4 0.0 2.6e-22 79.3 0.0 1.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) RAI16-like PF10257.4 KOS14450.1 - 4.9e-18 65.1 0.6 7e-18 64.6 0.4 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FHA PF00498.21 KOS14451.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain DAP3 PF10236.4 KOS14452.1 - 4e-59 200.0 0.0 5.2e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KOS14452.1 - 8.2e-07 29.1 0.6 2.9e-06 27.3 0.3 2.0 1 1 1 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KOS14452.1 - 0.00038 20.2 0.0 0.0094 15.6 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 KOS14452.1 - 0.00064 19.1 0.1 0.0031 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KOS14452.1 - 0.0022 17.4 0.0 0.0049 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KOS14452.1 - 0.0032 17.1 0.0 0.015 15.0 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KOS14452.1 - 0.008 16.3 0.0 0.064 13.4 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS14452.1 - 0.013 15.2 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS14452.1 - 0.016 15.3 0.1 0.27 11.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 KOS14452.1 - 0.1 11.4 0.3 1.3 7.7 0.0 2.4 2 0 0 2 2 2 0 MCM2/3/5 family SQS_PSY PF00494.14 KOS14453.1 - 1.7e-36 125.8 0.0 2.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase zf-DHHC PF01529.15 KOS14453.1 - 0.7 9.2 2.8 21 4.4 1.8 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Abhydrolase_6 PF12697.2 KOS14454.1 - 7.3e-26 91.4 4.9 9.3e-26 91.1 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS14454.1 - 5.2e-11 42.4 0.1 1.2e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KOS14454.1 - 4e-08 33.7 0.1 6.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KOS14454.1 - 5.3e-08 32.6 0.1 6.3e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KOS14454.1 - 9.5e-06 25.3 0.1 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KOS14454.1 - 0.0018 17.8 0.1 0.005 16.4 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KOS14454.1 - 0.0063 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2305 PF10230.4 KOS14454.1 - 0.015 14.7 0.0 0.086 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF2974 PF11187.3 KOS14454.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KOS14454.1 - 0.023 14.3 0.1 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KOS14454.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Chlorophyllase PF07224.6 KOS14454.1 - 0.07 11.9 0.0 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase RNA_pol_Rpb8 PF03870.10 KOS14455.1 - 1e-41 142.3 0.1 1.2e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 FTR1 PF03239.9 KOS14456.1 - 3.9e-53 180.3 3.1 2e-34 118.9 0.2 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3169 PF11368.3 KOS14456.1 - 2.8e-05 23.4 3.3 0.0067 15.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3169) O-antigen_lig PF13425.1 KOS14456.1 - 0.057 13.3 17.4 0.78 9.7 0.6 3.4 2 1 0 3 3 3 0 O-antigen ligase like membrane protein Thia_YuaJ PF09515.5 KOS14456.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.8 3 1 1 4 4 4 0 Thiamine transporter protein (Thia_YuaJ) Wzy_C PF04932.10 KOS14456.1 - 0.42 10.3 10.3 0.31 10.8 0.3 3.1 3 0 0 3 3 3 0 O-Antigen ligase DUF3981 PF13139.1 KOS14456.1 - 0.47 10.4 3.7 0.44 10.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) Metallophos PF00149.23 KOS14457.1 - 1.6e-09 37.4 0.0 3.6e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS14457.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Polysacc_synt_4 PF04669.8 KOS14458.1 - 1.9e-26 92.6 4.4 1.1e-25 90.1 3.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Aconitase PF00330.15 KOS14459.1 - 5.8e-71 239.3 0.1 2.3e-47 161.5 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS14459.1 - 5.1e-19 68.6 0.0 1.3e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Glu_synthase PF01645.12 KOS14459.1 - 0.006 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aconitase_2_N PF06434.8 KOS14459.1 - 0.12 11.8 0.0 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus Pkinase PF00069.20 KOS14460.1 - 5.3e-69 232.2 0.0 6.7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14460.1 - 1.4e-32 112.7 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS14460.1 - 0.034 13.2 0.0 0.077 12.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KOS14460.1 - 0.056 12.4 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KOS14460.1 - 0.059 13.0 0.1 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KOS14460.1 - 0.11 11.7 0.7 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF566 PF04484.7 KOS14460.1 - 1.5 8.2 10.6 2 7.8 7.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 KOS14460.1 - 1.7 8.4 8.5 2.2 8.0 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.15 KOS14461.1 - 3.8e-72 242.8 0.0 5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS14461.1 - 7.2e-11 41.7 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF383 PF04063.9 KOS14461.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF1682 PF07946.9 KOS14461.1 - 0.57 8.9 3.0 1 8.1 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GTP_EFTU PF00009.22 KOS14462.1 - 9.5e-60 201.2 1.2 1e-59 201.1 0.3 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS14462.1 - 1.7e-28 98.6 0.0 3.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS14462.1 - 8.7e-16 57.8 4.4 2.3e-15 56.4 3.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS14462.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KOS14462.1 - 0.0001 21.8 0.4 0.00025 20.6 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KOS14462.1 - 0.0052 17.2 0.0 0.0095 16.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KOS14462.1 - 0.056 12.9 0.4 9.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KOS14462.1 - 0.092 12.1 1.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KOS14462.1 - 0.13 12.5 0.3 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter BCDHK_Adom3 PF10436.4 KOS14463.1 - 2.9e-45 153.7 0.0 3.8e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KOS14463.1 - 3.5e-12 46.0 0.0 1.2e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS14463.1 - 1.7e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1400 PF07176.6 KOS14463.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) NPL4 PF05021.10 KOS14464.1 - 2.8e-100 335.4 0.0 3.6e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KOS14464.1 - 4.1e-67 224.4 0.4 6.3e-67 223.8 0.3 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DZR PF12773.2 KOS14464.1 - 0.035 13.9 0.7 0.035 13.9 0.5 2.6 3 0 0 3 3 3 0 Double zinc ribbon UN_NPL4 PF11543.3 KOS14464.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Trep_dent_lipo PF09710.5 KOS14464.1 - 0.33 9.5 0.0 0.48 9.0 0.0 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Hydantoinase_A PF01968.13 KOS14465.1 - 1.9e-88 296.3 0.9 3.3e-88 295.5 0.6 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KOS14465.1 - 4.1e-58 195.7 0.3 3.7e-56 189.3 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Ribosomal_L29 PF00831.18 KOS14466.1 - 2.8e-18 65.3 3.0 2.8e-18 65.3 2.1 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KOS14466.1 - 0.025 14.8 3.7 0.03 14.5 2.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Dynamitin PF04912.9 KOS14466.1 - 0.046 12.5 3.6 0.051 12.3 2.5 1.1 1 0 0 1 1 1 0 Dynamitin RRM_1 PF00076.17 KOS14467.1 - 3.7e-19 68.1 0.0 5.6e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14467.1 - 4.6e-14 51.9 0.5 1.2e-09 37.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14467.1 - 1.8e-12 47.0 0.0 5.4e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KOS14467.1 - 5.3e-05 22.8 0.0 0.00019 21.0 0.0 1.8 2 0 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 KOS14467.1 - 0.0073 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 DUF4523 PF15023.1 KOS14467.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ilar_coat PF01787.11 KOS14467.1 - 0.18 11.3 1.6 0.27 10.7 1.1 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein Translin PF01997.11 KOS14468.1 - 4.1e-39 134.2 0.0 5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Translin family GDI PF00996.13 KOS14469.1 - 1.9e-202 672.3 0.0 2.2e-202 672.1 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KOS14469.1 - 0.019 14.9 0.0 0.067 13.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aminotran_5 PF00266.14 KOS14470.1 - 7.2e-32 110.5 0.0 9.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KOS14470.1 - 0.0039 17.0 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Beta_elim_lyase PF01212.16 KOS14470.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase YtxH PF12732.2 KOS14470.1 - 0.1 12.9 0.1 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 YtxH-like protein Aldo_ket_red PF00248.16 KOS14471.1 - 1e-47 162.2 0.0 1.2e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family peroxidase PF00141.18 KOS14472.1 - 7.6e-50 169.5 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase S1 PF00575.18 KOS14473.1 - 4e-52 174.1 8.1 4e-13 49.2 0.1 10.0 9 0 0 9 9 9 6 S1 RNA binding domain TPR_14 PF13428.1 KOS14473.1 - 3.6e-11 42.6 7.2 0.0035 17.8 0.1 5.2 6 1 0 6 6 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14473.1 - 3.1e-10 40.2 0.0 0.03 14.6 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS14473.1 - 1.2e-09 38.6 3.5 0.057 14.1 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14473.1 - 4.3e-07 29.3 1.7 1.2 9.2 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14473.1 - 2.8e-06 27.4 1.6 0.042 14.3 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14473.1 - 2.8e-06 27.1 2.5 0.87 9.5 0.6 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 KOS14473.1 - 8.8e-05 22.3 4.5 0.012 15.4 0.2 3.6 2 2 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_1 PF00515.23 KOS14473.1 - 0.00016 21.1 0.1 0.055 13.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS14473.1 - 0.00047 19.7 0.7 2.4 7.8 0.0 3.4 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.1 KOS14473.1 - 0.011 15.4 0.1 13 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14473.1 - 0.02 14.6 0.5 2.4 8.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KOS14473.1 - 0.028 14.3 0.1 2.3 8.3 0.0 3.6 4 0 0 4 4 3 0 PPR repeat SPOB_a PF14689.1 KOS14473.1 - 0.054 13.0 0.1 5.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_17 PF13431.1 KOS14473.1 - 0.18 12.0 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat P34-Arc PF04045.9 KOS14474.1 - 6e-105 349.8 0.0 7.4e-105 349.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Hemerythrin PF01814.18 KOS14474.1 - 0.075 13.2 0.3 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain HAMP PF00672.20 KOS14475.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 HAMP domain Sigma70_ner PF04546.8 KOS14475.1 - 0.036 13.6 9.9 0.04 13.5 6.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF305 PF03713.8 KOS14475.1 - 0.11 12.2 0.9 0.14 11.9 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF305) DUF4407 PF14362.1 KOS14475.1 - 0.3 9.9 3.4 0.35 9.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-protein PF00469.15 KOS14475.1 - 0.57 9.5 4.3 0.64 9.3 3.0 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Nucleoplasmin PF03066.10 KOS14475.1 - 0.87 9.0 7.2 0.86 9.1 5.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KOS14475.1 - 2.4 8.5 15.0 2.3 8.5 9.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KOS14475.1 - 6.3 5.9 9.2 6.6 5.8 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 KOS14475.1 - 6.9 6.5 19.3 8.1 6.2 13.4 1.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LSM PF01423.17 KOS14476.1 - 8e-09 34.9 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 KOS14477.1 - 9.7e-35 119.5 0.1 1.5e-34 118.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS14477.1 - 1.4e-22 79.2 0.2 2e-11 43.5 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KOS14477.1 - 8.6e-06 25.7 0.0 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arc_trans_TRASH PF08394.5 KOS14477.1 - 0.018 15.1 1.1 0.048 13.8 0.8 1.7 1 0 0 1 1 1 0 Archaeal TRASH domain Helicase_RecD PF05127.9 KOS14477.1 - 0.06 12.9 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Helicase CAF-1_p150 PF11600.3 KOS14478.1 - 0.37 10.1 60.7 0.063 12.6 35.5 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 KOS14478.1 - 5.2 5.5 3.2 7.9 4.9 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ish1 PF10281.4 KOS14479.1 - 1.9e-41 139.7 28.3 2.3e-08 33.9 0.7 6.8 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KOS14479.1 - 4.4e-07 29.2 0.0 0.033 13.7 0.0 4.2 4 0 0 4 4 4 2 SAP domain HeH PF12949.2 KOS14479.1 - 9e-06 25.1 0.1 3 7.4 0.0 4.7 4 0 0 4 4 4 3 HeH/LEM domain LEM PF03020.10 KOS14479.1 - 0.038 13.4 0.0 11 5.5 0.0 3.5 3 0 0 3 3 3 0 LEM domain SAM_2 PF07647.12 KOS14479.1 - 0.36 10.7 3.1 24 4.8 0.1 3.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) LRR_4 PF12799.2 KOS14480.1 - 1.5e-17 62.7 9.4 1.4e-07 30.9 1.0 5.4 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS14480.1 - 3e-16 58.9 11.2 6.8e-11 41.7 2.7 4.8 3 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KOS14480.1 - 4.3e-11 41.2 13.3 0.47 10.6 0.5 8.3 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS14480.1 - 6.7e-09 34.5 18.8 0.77 10.2 0.6 8.5 8 0 0 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 KOS14480.1 - 1.9e-05 24.3 0.1 0.00071 19.1 0.0 2.6 1 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 KOS14480.1 - 0.0039 17.1 14.2 39 4.7 0.4 7.4 7 1 1 8 8 8 0 Leucine Rich repeat MIP-T3 PF10243.4 KOS14480.1 - 7.7 4.8 29.8 11 4.3 20.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RINT1_TIP1 PF04437.8 KOS14481.1 - 3.2e-65 220.5 0.0 6.8e-65 219.5 0.0 1.5 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Exo_endo_phos PF03372.18 KOS14482.1 - 8e-13 48.8 0.8 5.2e-08 33.1 0.1 2.6 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Caldesmon PF02029.10 KOS14482.1 - 0.11 10.8 9.5 0.18 10.1 6.6 1.2 1 0 0 1 1 1 0 Caldesmon Phosphodiest PF01663.17 KOS14483.1 - 2e-12 47.1 0.2 3.7e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MadM PF03818.8 KOS14483.1 - 0.00036 20.0 0.2 0.0016 17.9 0.2 2.1 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit Metalloenzyme PF01676.13 KOS14483.1 - 0.00048 19.5 0.2 0.00084 18.7 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KOS14483.1 - 0.0046 16.2 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase CHD5 PF04420.9 KOS14485.1 - 1.6e-38 131.8 0.1 2e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF106 PF01956.11 KOS14485.1 - 0.6 9.6 6.0 1.2 8.6 4.1 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 TPP_enzyme_N PF02776.13 KOS14486.1 - 3.3e-37 127.6 0.1 7.1e-37 126.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KOS14486.1 - 2.1e-23 82.6 0.0 1.5e-22 79.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KOS14486.1 - 1.2e-17 63.8 0.4 3.7e-17 62.3 0.0 1.9 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RRM_6 PF14259.1 KOS14487.1 - 3.4e-05 23.7 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14487.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS14487.1 - 0.2 11.3 0.0 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ApbA_C PF08546.6 KOS14490.1 - 2.2e-21 76.1 0.0 3.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KOS14490.1 - 7.7e-18 64.3 0.0 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Iso_dh PF00180.15 KOS14491.1 - 3.9e-100 335.1 0.0 4.6e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4448 PF14610.1 KOS14492.1 - 1e-08 34.9 0.6 9.7e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KOS14492.1 - 5.8e-05 22.3 0.2 0.00012 21.3 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 KOS14492.1 - 0.038 12.6 0.1 0.062 11.9 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-CCCH PF00642.19 KOS14493.1 - 4.2e-17 61.3 16.5 2.5e-09 36.5 1.3 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KOS14493.1 - 0.051 13.1 10.9 0.15 11.6 0.1 3.5 2 1 1 3 3 3 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 KOS14493.1 - 0.084 12.8 10.9 0.49 10.4 0.4 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_60s PF00428.14 KOS14493.1 - 7.6 7.0 9.0 42 4.6 3.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.20 KOS14494.1 - 1.1e-45 155.8 0.0 2.6e-45 154.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14494.1 - 2.5e-18 66.0 0.0 4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS14494.1 - 3.9e-06 26.7 1.6 1.1e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS14494.1 - 2.1e-05 23.6 0.0 3.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KOS14494.1 - 0.0005 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KOS14494.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAD_binding_3 PF01494.14 KOS14495.1 - 8.6e-21 74.3 3.1 2e-09 36.9 1.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KOS14495.1 - 7.4e-05 22.5 0.2 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KOS14495.1 - 0.0028 16.5 2.8 0.22 10.3 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase SE PF08491.5 KOS14495.1 - 0.0029 16.4 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KOS14495.1 - 0.0066 15.4 1.3 0.88 8.4 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 KOS14495.1 - 0.085 13.2 0.1 13 6.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS14495.1 - 0.12 11.4 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family RNA_pol_Rpb1_1 PF04997.7 KOS14496.1 - 4.8e-108 361.3 0.0 6.3e-108 361.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KOS14496.1 - 5.4e-103 344.0 0.0 8.1e-103 343.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KOS14496.1 - 3.5e-69 232.0 0.0 5.9e-69 231.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KOS14496.1 - 2.5e-60 203.4 0.0 5.4e-60 202.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KOS14496.1 - 8.3e-47 158.8 0.0 1.6e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KOS14496.1 - 3.9e-46 156.1 0.4 8.6e-46 155.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KOS14496.1 - 4e-37 126.2 0.0 8.9e-37 125.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KOS14496.1 - 1.7e-17 61.8 186.8 0.012 15.6 6.8 13.0 7 2 10 17 17 17 17 RNA polymerase Rpb1 C-terminal repeat DUF3712 PF12505.3 KOS14497.1 - 2.3e-106 350.7 22.4 1.6e-22 79.8 0.3 9.2 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KOS14497.1 - 4.8e-08 33.2 10.8 0.0065 16.8 0.0 6.7 6 0 0 6 6 6 2 Late embryogenesis abundant protein DUF1510 PF07423.6 KOS14498.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4097 PF13349.1 KOS14498.1 - 0.11 12.0 1.2 0.17 11.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Synaptobrevin PF00957.16 KOS14498.1 - 3.1 7.4 4.2 5.1 6.7 2.9 1.3 1 0 0 1 1 1 0 Synaptobrevin SoxE PF06525.6 KOS14498.1 - 3.4 6.8 5.8 0.82 8.9 0.0 2.4 2 1 0 2 2 2 0 Sulfocyanin (SoxE) UAA PF08449.6 KOS14499.1 - 3.1e-75 252.9 11.2 3.5e-75 252.7 7.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KOS14499.1 - 0.4 10.3 15.1 0.021 14.5 5.8 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4231 PF14015.1 KOS14499.1 - 0.51 10.3 0.1 0.51 10.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Sugar_tr PF00083.19 KOS14500.1 - 9.3e-85 284.8 26.8 1.1e-84 284.6 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS14500.1 - 1.1e-15 57.2 46.6 7.3e-14 51.2 8.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Retrotrans_gag PF03732.12 KOS14500.1 - 0.07 13.2 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein SRP54 PF00448.17 KOS14501.1 - 4e-44 150.4 0.0 1.3e-42 145.5 0.0 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KOS14501.1 - 5.6e-36 124.3 8.3 2.3e-26 92.7 0.3 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 KOS14501.1 - 4.1e-06 26.3 0.0 8.1e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KOS14501.1 - 2.5e-05 23.2 0.0 0.00014 20.7 0.0 1.9 1 1 0 1 1 1 1 ArgK protein SRP54_N PF02881.14 KOS14501.1 - 6.1e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MobB PF03205.9 KOS14501.1 - 0.0025 17.5 0.0 0.007 16.0 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KOS14501.1 - 0.015 15.4 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 KOS14501.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Pyrid_oxidase_2 PF13883.1 KOS14502.1 - 8.4e-21 74.4 0.1 1.1e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_L30_N PF08079.7 KOS14503.1 - 2.3e-26 91.6 17.2 4.3e-26 90.7 11.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KOS14503.1 - 2.1e-17 62.4 0.4 2.1e-17 62.4 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PGC7_Stella PF15549.1 KOS14503.1 - 0.25 11.2 5.5 0.41 10.6 3.8 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain FA_hydroxylase PF04116.8 KOS14504.1 - 2.4e-14 53.7 19.5 2.4e-14 53.7 13.5 2.2 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily HSP70 PF00012.15 KOS14505.1 - 1.3e-155 518.7 0.0 3.7e-155 517.2 0.0 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KOS14505.1 - 5.9e-10 38.2 0.0 9.5e-10 37.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 KOS14505.1 - 0.03 14.1 1.4 24 4.8 0.1 3.5 3 1 0 3 3 3 0 Cell division protein FtsA Nnf1 PF03980.9 KOS14506.1 - 1.7e-09 37.6 2.0 1.7e-09 37.6 1.4 1.9 1 1 1 2 2 2 1 Nnf1 CENP-Q PF13094.1 KOS14506.1 - 0.0043 17.0 3.0 0.0043 17.0 2.1 2.1 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 KOS14506.1 - 0.021 14.6 3.6 0.022 14.5 0.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 KOS14506.1 - 0.023 14.3 1.4 0.023 14.3 0.9 1.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF904 PF06005.7 KOS14506.1 - 0.068 13.4 0.3 0.068 13.4 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Condensation PF00668.15 KOS14506.1 - 0.11 11.3 1.9 0.14 10.9 1.0 1.4 1 1 0 1 1 1 0 Condensation domain ATG16 PF08614.6 KOS14506.1 - 0.11 12.3 4.7 0.13 12.0 2.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.16 KOS14506.1 - 0.2 11.0 7.0 0.22 10.9 3.7 1.9 1 1 1 2 2 2 0 Intermediate filament protein DivIC PF04977.10 KOS14506.1 - 0.21 11.0 5.9 0.071 12.6 0.6 2.3 2 1 0 2 2 2 0 Septum formation initiator Siah-Interact_N PF09032.6 KOS14506.1 - 0.23 11.5 3.7 0.48 10.5 0.9 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal KxDL PF10241.4 KOS14506.1 - 0.26 11.2 3.5 0.58 10.1 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein Mnd1 PF03962.10 KOS14506.1 - 0.92 9.1 3.8 2.2 7.9 2.7 1.7 1 1 0 1 1 1 0 Mnd1 family TMF_TATA_bd PF12325.3 KOS14506.1 - 2.2 8.0 5.7 0.57 9.9 0.8 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.1 KOS14506.1 - 2.5 8.5 13.4 2.1 8.8 5.7 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) M PF02370.11 KOS14506.1 - 6.5 7.4 11.5 0.43 11.0 0.9 4.0 4 0 0 4 4 4 0 M protein repeat Skp1_POZ PF03931.10 KOS14507.1 - 1.8e-09 37.5 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain APS_kinase PF01583.15 KOS14508.1 - 1.5e-69 232.6 0.0 1.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KOS14508.1 - 8e-07 29.0 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS14508.1 - 1.1e-05 26.2 0.0 1.9e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS14508.1 - 2.2e-05 24.7 0.0 3.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KOS14508.1 - 0.00021 20.5 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KOS14508.1 - 0.0011 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KOS14508.1 - 0.0045 16.1 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 KOS14508.1 - 0.021 15.1 0.0 0.077 13.3 0.0 1.7 1 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KOS14508.1 - 0.1 12.6 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 KOS14508.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_23 PF13476.1 KOS14508.1 - 0.12 12.7 0.1 0.15 12.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 KOS14509.1 - 9.1e-31 107.0 3.0 1.3e-30 106.5 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS14509.1 - 1.1e-13 51.5 0.1 1.3e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS14509.1 - 1.9e-11 43.9 1.4 2.7e-11 43.4 1.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KOS14509.1 - 7.1e-05 22.5 0.4 0.00014 21.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KOS14509.1 - 0.0095 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KOS14509.1 - 0.0096 15.3 0.2 0.023 14.1 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KOS14509.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 KOS14509.1 - 0.017 14.7 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KOS14509.1 - 0.052 13.6 0.3 0.13 12.3 0.2 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KOS14509.1 - 0.079 12.9 2.9 0.15 12.0 2.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 KOS14509.1 - 0.094 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AAA PF00004.24 KOS14510.1 - 1.5e-96 319.6 0.0 3.2e-47 160.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KOS14510.1 - 5.8e-16 58.2 0.1 1.9e-15 56.5 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KOS14510.1 - 5.8e-14 51.7 0.1 1.2e-05 24.4 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS14510.1 - 5.4e-13 49.0 0.0 1.8e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KOS14510.1 - 5.9e-13 49.0 0.0 2.3e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KOS14510.1 - 5.1e-12 45.7 0.6 5.6e-06 26.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 KOS14510.1 - 2.2e-11 43.2 0.0 4.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 KOS14510.1 - 3.3e-11 44.0 0.5 0.00065 20.5 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 KOS14510.1 - 4.2e-11 43.0 0.2 0.0021 18.2 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KOS14510.1 - 1.1e-09 38.5 0.6 0.0018 18.3 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 KOS14510.1 - 3.2e-09 35.9 0.1 0.0012 17.6 0.0 2.5 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KOS14510.1 - 3.3e-08 33.1 3.7 0.013 14.8 0.0 4.4 3 2 2 5 5 5 2 AAA domain IstB_IS21 PF01695.12 KOS14510.1 - 3.3e-08 33.1 0.0 0.0036 16.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KOS14510.1 - 4.7e-08 32.3 0.0 0.0072 15.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KOS14510.1 - 1.4e-07 31.1 1.0 0.0084 15.8 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KOS14510.1 - 2.4e-07 30.7 0.0 0.0067 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KOS14510.1 - 3.2e-07 29.7 0.3 0.021 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS14510.1 - 1.1e-06 28.7 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 KOS14510.1 - 1.3e-06 27.6 1.1 0.51 9.4 0.0 3.4 2 1 1 3 3 3 2 KaiC Vps4_C PF09336.5 KOS14510.1 - 2e-06 27.5 0.0 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 KOS14510.1 - 2.5e-06 27.8 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KOS14510.1 - 3.8e-06 26.9 0.1 0.1 12.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 KOS14510.1 - 6.8e-06 26.4 0.0 0.043 14.1 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 KOS14510.1 - 7.1e-06 25.0 0.1 0.0076 15.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KOS14510.1 - 7.1e-06 25.9 0.0 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 KOS14510.1 - 1.4e-05 24.5 0.0 0.36 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KOS14510.1 - 2.2e-05 23.7 0.1 0.21 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KOS14510.1 - 2.3e-05 24.1 0.0 0.1 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Sigma54_activ_2 PF14532.1 KOS14510.1 - 2.3e-05 24.4 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KOS14510.1 - 2.9e-05 23.1 0.0 0.0089 14.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KOS14510.1 - 6.6e-05 22.7 0.0 1.4 8.5 0.0 3.3 2 1 1 3 3 3 2 Archaeal ATPase Bac_DnaA PF00308.13 KOS14510.1 - 8e-05 22.3 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 KOS14510.1 - 0.00011 21.8 0.0 0.5 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KOS14510.1 - 0.00017 21.1 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KOS14510.1 - 0.00029 20.5 0.1 0.48 10.0 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.1 KOS14510.1 - 0.0007 19.2 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KOS14510.1 - 0.0017 17.4 1.7 0.34 9.8 0.0 2.7 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KOS14510.1 - 0.0025 16.7 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KOS14510.1 - 0.0034 17.0 0.4 1.1 8.9 0.0 3.4 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 KOS14510.1 - 0.0036 16.8 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KOS14510.1 - 0.0087 14.9 0.0 0.27 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KOS14510.1 - 0.012 15.0 1.3 4.9 6.4 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain KAP_NTPase PF07693.9 KOS14510.1 - 0.03 13.3 0.0 0.44 9.4 0.0 2.5 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 KOS14510.1 - 0.032 13.3 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KOS14510.1 - 0.035 13.7 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 KOS14510.1 - 0.056 12.6 0.0 7.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 KOS14510.1 - 0.085 12.3 0.0 6.6 6.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KOS14510.1 - 0.12 12.0 0.2 8.8 6.0 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 KOS14510.1 - 0.13 11.7 0.2 62 3.0 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase Zot PF05707.7 KOS14510.1 - 0.14 11.6 0.1 24 4.3 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 KOS14510.1 - 0.22 11.4 2.0 7.2 6.4 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase SET PF00856.23 KOS14511.1 - 3e-14 53.6 0.0 7.5e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KOS14511.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Astro_capsid PF03115.9 KOS14511.1 - 0.23 9.6 2.1 0.32 9.2 1.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor UQ_con PF00179.21 KOS14512.1 - 9e-46 154.7 0.0 1e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KOS14512.1 - 0.25 11.2 1.4 0.74 9.7 1.0 2.0 1 1 0 1 1 1 0 RWD domain PrsW-protease PF13367.1 KOS14513.1 - 1e-11 44.4 1.2 1.8e-11 43.6 0.8 1.4 1 1 0 1 1 1 1 Protease prsW family tRNA-synt_2b PF00587.20 KOS14514.1 - 1.7e-66 223.0 0.1 2.7e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS14514.1 - 1.1e-22 79.7 0.0 3.5e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain RFC1 PF08519.7 KOS14514.1 - 0.0026 17.5 0.1 0.008 15.9 0.1 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain SpoIIIAH PF12685.2 KOS14514.1 - 0.018 14.5 1.1 0.036 13.5 0.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Ribosomal_60s PF00428.14 KOS14514.1 - 0.88 10.0 11.5 3.4 8.1 8.0 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3419 PF11899.3 KOS14515.1 - 2.1e-140 467.7 0.0 2.9e-140 467.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KOS14515.1 - 1.4e-09 37.8 0.0 5.1e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14515.1 - 1.7e-08 34.1 0.0 4.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS14515.1 - 1.4e-07 31.8 0.0 1.3e-05 25.5 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS14515.1 - 2.2e-07 30.2 0.0 3.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KOS14515.1 - 6.4e-06 26.5 0.0 2.2e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14515.1 - 0.00012 22.4 0.0 0.0012 19.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS14515.1 - 0.00051 20.6 0.0 0.0019 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS14515.1 - 0.015 14.3 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KOS14515.1 - 0.057 13.4 0.0 0.9 9.5 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain zf-H2C2_2 PF13465.1 KOS14516.1 - 5.7e-26 89.4 16.0 2.3e-07 30.7 0.1 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KOS14516.1 - 5.9e-22 76.6 23.2 2.1e-05 24.6 1.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS14516.1 - 4.7e-15 54.7 20.3 0.00041 20.4 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS14516.1 - 7.9e-07 29.0 6.8 0.023 14.8 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KOS14516.1 - 0.00037 20.2 10.4 0.03 14.2 0.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KOS14516.1 - 0.0014 18.7 11.2 0.27 11.5 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KOS14516.1 - 0.011 16.0 8.9 0.13 12.7 0.3 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 KOS14516.1 - 2 8.1 6.0 8.6 6.1 0.3 2.9 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger Septin PF00735.13 KOS14517.1 - 5.4e-103 343.8 0.1 6.8e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KOS14517.1 - 3.9e-08 33.2 0.0 8.3e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KOS14517.1 - 2.9e-07 29.8 0.1 8.7e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 KOS14517.1 - 5.6e-06 25.9 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KOS14517.1 - 5.9e-06 25.5 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS14517.1 - 2.6e-05 24.1 0.4 0.14 12.0 0.1 2.4 1 1 1 2 2 2 2 Dynamin family Gtr1_RagA PF04670.7 KOS14517.1 - 6.3e-05 22.2 0.2 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KOS14517.1 - 0.0029 17.0 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KOS14517.1 - 0.0047 16.3 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KOS14517.1 - 0.0066 16.7 0.2 0.012 15.8 0.1 1.6 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 KOS14517.1 - 0.02 13.7 0.1 0.056 12.3 0.0 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_29 PF13555.1 KOS14517.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KOS14517.1 - 0.022 13.8 0.0 0.79 8.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS14517.1 - 0.029 14.5 0.1 0.64 10.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_32 PF13654.1 KOS14517.1 - 0.036 12.7 0.9 0.12 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KOS14517.1 - 0.038 14.4 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Ras PF00071.17 KOS14517.1 - 0.038 13.3 0.0 0.12 11.7 0.0 2.1 1 1 0 1 1 1 0 Ras family PduV-EutP PF10662.4 KOS14517.1 - 0.069 12.6 0.1 1.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CKS PF01111.14 KOS14518.1 - 2.1e-34 117.1 0.4 2.7e-34 116.8 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KOS14518.1 - 0.33 11.0 0.6 0.33 11.0 0.4 2.0 2 0 0 2 2 2 0 APC 15 residue motif MutS_V PF00488.16 KOS14519.1 - 7.8e-76 254.5 0.1 1.4e-75 253.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KOS14519.1 - 1.4e-38 132.7 0.6 2.5e-38 131.9 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KOS14519.1 - 7.4e-35 119.3 0.0 1.8e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KOS14519.1 - 1.8e-13 50.7 0.0 5.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KOS14519.1 - 2.8e-09 37.0 0.2 6.9e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV Nucleo_P87 PF07267.6 KOS14519.1 - 1.3 7.5 10.0 2.7 6.5 7.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.7 KOS14519.1 - 1.4 6.7 13.2 2.2 6.0 9.2 1.2 1 0 0 1 1 1 0 Nop14-like family FAT PF02259.18 KOS14520.1 - 1.4e-114 382.7 0.4 1.4e-114 382.7 0.3 2.5 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 KOS14520.1 - 7.1e-55 186.0 0.1 1.4e-54 185.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KOS14520.1 - 2e-54 183.8 0.1 1.7e-53 180.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KOS14520.1 - 2.4e-41 139.8 0.3 2.4e-41 139.8 0.2 3.4 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 KOS14520.1 - 4.7e-21 74.8 22.7 0.00055 20.1 0.1 10.3 6 2 4 10 10 10 6 HEAT repeats FATC PF02260.15 KOS14520.1 - 1.2e-14 53.3 0.2 3.6e-14 51.8 0.2 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KOS14520.1 - 2.4e-09 36.4 21.2 0.025 14.6 0.0 11.9 14 0 0 14 14 13 2 HEAT repeat HEAT_EZ PF13513.1 KOS14520.1 - 6.2e-08 32.9 32.4 0.043 14.3 0.0 12.4 11 3 3 15 15 15 3 HEAT-like repeat TPR_19 PF14559.1 KOS14520.1 - 0.00057 20.1 0.0 8.2 6.8 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_PBS PF03130.11 KOS14520.1 - 0.0049 17.2 3.6 13 6.6 0.1 6.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_16 PF13432.1 KOS14520.1 - 0.005 17.4 0.7 4.8 7.9 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Cnd1 PF12717.2 KOS14520.1 - 0.099 12.4 2.4 0.52 10.1 0.0 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KOS14520.1 - 0.13 12.0 3.9 5.7 6.9 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TPR_2 PF07719.12 KOS14520.1 - 0.56 10.2 4.8 30 4.8 0.4 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 KOS14521.1 - 4.1e-68 227.8 0.4 4.8e-68 227.6 0.3 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone zf-UBR PF02207.15 KOS14522.1 - 5.1e-11 42.1 9.5 5.1e-11 42.1 6.6 3.5 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 KOS14522.1 - 0.00044 19.8 6.8 0.00044 19.8 4.7 4.1 3 2 1 4 4 4 1 PHD-finger zf-PHD-like PF15446.1 KOS14522.1 - 3.1 7.0 14.5 0.17 11.1 0.1 3.3 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain LSM PF01423.17 KOS14523.1 - 2.8e-12 45.9 0.0 3.3e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS14523.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Hist_deacetyl PF00850.14 KOS14524.1 - 1.8e-77 260.7 0.0 2.4e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SMN PF06003.7 KOS14524.1 - 1.9 7.5 12.8 3.2 6.7 8.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HCO3_cotransp PF00955.16 KOS14525.1 - 4.7e-44 150.9 16.0 8e-25 87.4 2.6 3.1 2 1 1 3 3 3 3 HCO3- transporter family Acid_PPase PF12689.2 KOS14526.1 - 1.2e-61 207.2 0.0 1.4e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KOS14526.1 - 1.6e-05 25.1 1.1 7.1e-05 23.0 0.1 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_L29e PF01779.12 KOS14527.1 - 2.5e-25 88.0 9.4 3.8e-25 87.4 6.5 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Oxidored_q6 PF01058.17 KOS14528.1 - 5.3e-22 77.8 0.0 7.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit EMP24_GP25L PF01105.19 KOS14529.1 - 1.9e-44 151.5 0.1 2.2e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PS_Dcarbxylase PF02666.10 KOS14530.1 - 7.9e-74 247.3 0.0 1.7e-72 243.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Sld5 PF05916.6 KOS14532.1 - 0.00012 22.3 0.0 0.00016 21.9 0.0 1.3 1 1 0 1 1 1 1 GINS complex protein HK PF02110.10 KOS14533.1 - 5.1e-66 222.3 6.1 1.3e-62 211.1 4.2 2.5 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KOS14533.1 - 3.4e-43 146.8 0.8 6.4e-43 145.9 0.1 1.8 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 KOS14533.1 - 9.7e-05 21.6 1.7 0.00016 20.9 0.6 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF4507 PF14964.1 KOS14533.1 - 0.031 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) DUF3280 PF11684.3 KOS14533.1 - 0.036 14.2 0.3 0.088 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) Orn_Arg_deC_N PF02784.11 KOS14534.1 - 9.1e-68 228.1 0.0 1.2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KOS14534.1 - 3.9e-30 103.9 0.0 6.2e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Glyco_transf_41 PF13844.1 KOS14534.1 - 0.12 10.3 0.0 0.18 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 G_glu_transpept PF01019.16 KOS14535.1 - 1.5e-142 475.7 0.0 1.7e-142 475.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GATase_4 PF13230.1 KOS14536.1 - 1.2e-20 73.3 0.0 3.7e-20 71.7 0.0 1.8 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KOS14536.1 - 3.3e-10 40.0 0.0 7.4e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KOS14536.1 - 1.5e-07 30.4 0.0 3.4e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 KOS14536.1 - 0.14 11.9 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain WD40 PF00400.27 KOS14537.1 - 8.9e-47 155.3 1.3 5.3e-11 41.9 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS14537.1 - 6.4e-12 44.3 9.2 0.00016 20.0 0.2 4.8 2 2 3 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KOS14537.1 - 0.027 13.9 0.4 5.7 6.3 0.0 2.8 2 1 1 3 3 3 0 PQQ-like domain DUF724 PF05266.9 KOS14537.1 - 0.92 9.0 6.9 2.6 7.6 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 KOS14537.1 - 2.2 7.2 9.8 3.3 6.6 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Voltage_CLC PF00654.15 KOS14538.1 - 2.3e-90 303.1 30.0 2.3e-90 303.1 20.8 2.1 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KOS14538.1 - 2.3e-11 43.2 0.0 1.9e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain PCI PF01399.22 KOS14539.1 - 7.7e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3359 PF11839.3 KOS14539.1 - 0.55 10.6 3.5 1.9 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3359) Ribosomal_L7Ae PF01248.21 KOS14540.1 - 1.8e-21 75.4 0.2 3.1e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CM_2 PF01817.16 KOS14541.1 - 0.0012 18.8 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 Chorismate mutase type II tRNA-synt_1g PF09334.6 KOS14542.1 - 1.1e-145 485.2 0.1 1.3e-145 484.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KOS14542.1 - 2e-09 36.9 7.8 6.6e-09 35.3 5.4 1.9 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 KOS14542.1 - 1.5e-07 29.8 0.1 0.00011 20.3 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) YwqJ-deaminase PF14431.1 KOS14542.1 - 0.013 15.3 0.5 2.1 8.2 0.1 3.0 3 0 0 3 3 3 0 YwqJ-like deaminase DZR PF12773.2 KOS14542.1 - 0.077 12.8 9.0 0.11 12.3 4.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon HalX PF08663.5 KOS14542.1 - 0.11 12.4 1.7 0.33 10.9 1.2 1.8 1 0 0 1 1 1 0 HalX domain zinc_ribbon_2 PF13240.1 KOS14542.1 - 5.6 6.5 8.8 19 4.9 3.3 2.9 2 1 0 2 2 2 0 zinc-ribbon domain DNA_topoisoIV PF00521.15 KOS14543.1 - 1.2e-124 416.4 0.0 2e-124 415.7 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KOS14543.1 - 4.5e-32 110.6 0.3 4.5e-32 110.6 0.2 1.7 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 KOS14543.1 - 1.2e-13 50.8 0.0 2.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KOS14543.1 - 1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS14543.1 - 0.00085 18.9 0.2 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinesin PF00225.18 KOS14544.1 - 3.9e-106 354.5 0.0 7.7e-106 353.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 KOS14544.1 - 2.4 7.9 17.0 5.9 6.6 1.9 3.9 2 1 1 3 3 3 0 Domain of unknown function DUF87 SAC3_GANP PF03399.11 KOS14545.1 - 3.2e-50 170.5 0.0 5.7e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family peroxidase PF00141.18 KOS14545.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Peroxidase Abhydrolase_3 PF07859.8 KOS14546.1 - 8.4e-30 103.9 0.0 1.2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KOS14546.1 - 2.4e-05 23.1 0.0 3.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KOS14546.1 - 0.00062 19.0 0.1 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS14546.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BSP_II PF05432.6 KOS14547.1 - 0.0055 16.0 24.3 0.0081 15.4 16.9 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 KOS14547.1 - 1.1 9.5 39.7 2.4 8.4 3.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SGT1 PF07093.6 KOS14547.1 - 2.4 6.4 27.9 3.8 5.7 19.3 1.4 1 0 0 1 1 1 0 SGT1 protein VanZ PF04892.7 KOS14548.1 - 3.1e-09 36.8 2.6 5e-09 36.2 1.8 1.3 1 1 0 1 1 1 1 VanZ like family Voltage_CLC PF00654.15 KOS14548.1 - 0.012 14.6 3.7 0.045 12.7 2.6 1.7 1 1 0 1 1 1 0 Voltage gated chloride channel DUF1275 PF06912.6 KOS14548.1 - 0.059 12.5 0.7 0.081 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Sec2p PF06428.6 KOS14549.1 - 2.5e-14 52.9 10.0 2.5e-14 52.9 6.9 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p RPAP1_N PF08621.5 KOS14549.1 - 0.077 12.5 0.3 0.077 12.5 0.2 3.2 4 0 0 4 4 4 0 RPAP1-like, N-terminal AAA_27 PF13514.1 KOS14549.1 - 0.38 8.3 18.3 0.55 7.8 12.7 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 KOS14549.1 - 4.9 5.4 10.3 7.2 4.8 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1762 PF08574.5 KOS14551.1 - 5.5e-08 33.1 20.5 1.5e-07 31.7 3.4 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF1762) WD40 PF00400.27 KOS14552.1 - 3.3e-57 188.4 13.4 2e-13 49.6 0.6 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS14552.1 - 8.7e-07 27.4 3.4 0.22 9.5 0.0 4.4 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS14552.1 - 1e-05 24.5 3.3 2.9 6.5 0.4 5.2 1 1 3 4 4 4 3 Nup133 N terminal like DUF3312 PF11768.3 KOS14552.1 - 0.0007 17.9 0.0 0.0012 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) eIF2A PF08662.6 KOS14552.1 - 0.00085 19.0 3.4 1.4 8.5 0.0 4.0 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KOS14552.1 - 0.0074 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.7 KOS14552.1 - 2.3 5.9 6.0 3.6 5.2 0.4 2.4 1 1 0 2 2 2 0 IKI3 family Sulfate_transp PF00916.15 KOS14553.1 - 2.2e-44 151.5 3.5 2.2e-44 151.5 2.4 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KOS14553.1 - 4.5e-13 48.8 0.0 8.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KOS14553.1 - 3e-12 45.9 0.1 1.2e-11 43.9 0.0 2.0 1 1 1 2 2 2 1 STAS domain STAS_2 PF13466.1 KOS14553.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 STAS domain Pkinase PF00069.20 KOS14554.1 - 8.8e-59 198.7 0.0 2.7e-58 197.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Abhydrolase_3 PF07859.8 KOS14554.1 - 2e-48 164.7 0.0 3.9e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 KOS14554.1 - 1.7e-22 79.7 0.0 3.4e-22 78.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2424 PF10340.4 KOS14554.1 - 8.7e-13 47.6 0.0 9.2e-12 44.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KOS14554.1 - 3.4e-06 26.8 0.0 2.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Kinase-like PF14531.1 KOS14554.1 - 1.5e-05 24.1 0.0 0.00025 20.1 0.0 2.8 3 1 0 3 3 3 1 Kinase-like YrbL-PhoP_reg PF10707.4 KOS14554.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL COesterase PF00135.23 KOS14554.1 - 0.012 14.3 0.0 3.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Carboxylesterase family Kdo PF06293.9 KOS14554.1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KOS14554.1 - 0.082 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HNF-1_N PF04814.8 KOS14554.1 - 2.8 7.9 9.0 3.3 7.7 0.6 2.4 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RNase_PH PF01138.16 KOS14555.1 - 1.4e-22 80.4 0.0 2.1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 BPL_LplA_LipB PF03099.14 KOS14556.1 - 2.2e-09 37.3 0.0 3.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Fe-S_biosyn PF01521.15 KOS14557.1 - 1.1e-13 51.1 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NAD_binding_5 PF07994.7 KOS14558.1 - 6.5e-112 373.8 0.0 7.7e-112 373.5 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KOS14558.1 - 5.2e-44 148.6 0.0 8.2e-44 148.0 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF89 PF01937.14 KOS14559.1 - 3e-99 332.1 0.0 1.5e-56 191.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF89 Ala_racemase_N PF01168.15 KOS14559.1 - 5.3e-33 114.4 0.1 3.4e-31 108.4 0.1 2.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_6 PF12697.2 KOS14560.1 - 1.3e-22 80.7 0.3 3.7e-22 79.3 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS14560.1 - 2.8e-18 66.3 0.2 1.1e-17 64.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS14560.1 - 3e-10 40.0 0.0 6.6e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS14560.1 - 1.8e-05 24.0 0.1 0.0025 17.0 0.0 3.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KOS14560.1 - 0.0017 18.1 0.1 0.0057 16.4 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KOS14560.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.9 KOS14560.1 - 0.01 15.0 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.5 KOS14560.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.13 KOS14560.1 - 0.025 14.0 0.3 0.15 11.4 0.2 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S10 PF00450.17 KOS14560.1 - 0.031 13.4 0.2 0.092 11.8 0.0 1.9 2 1 0 2 2 2 0 Serine carboxypeptidase Esterase_phd PF10503.4 KOS14560.1 - 0.11 11.7 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase SWIRM PF04433.12 KOS14561.1 - 3e-35 120.2 0.1 7.7e-35 118.8 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KOS14561.1 - 7.2e-08 32.3 0.1 7.2e-08 32.3 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS14561.1 - 2.2e-07 30.8 2.0 4.2e-07 29.9 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.12 KOS14561.1 - 1.1e-06 28.0 1.6 2.2e-06 27.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SNF2_N PF00176.18 KOS14562.1 - 6.1e-74 248.5 0.1 8.8e-74 247.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS14562.1 - 1.2e-16 60.3 0.1 2.1e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS14562.1 - 9.3e-09 35.3 0.0 3.3e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS14562.1 - 1e-05 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KOS14562.1 - 5.1e-05 22.2 0.0 0.00017 20.5 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.1 KOS14562.1 - 0.0067 16.4 0.4 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 DNA-binding domain HA2 PF04408.18 KOS14563.1 - 2.6e-14 53.0 0.2 8.6e-13 48.1 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS14563.1 - 8.6e-14 51.1 0.1 1.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KOS14563.1 - 2.5e-10 40.1 0.0 7.5e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KOS14563.1 - 6.3e-09 35.5 0.1 1.3e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS14563.1 - 0.00076 19.6 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KOS14563.1 - 0.00089 18.4 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 KOS14563.1 - 0.011 14.6 0.0 0.033 13.1 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KOS14563.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KOS14563.1 - 0.016 14.2 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF494 PF04361.8 KOS14563.1 - 0.044 13.4 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF494) ResIII PF04851.10 KOS14563.1 - 0.16 11.8 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit WD40 PF00400.27 KOS14564.1 - 2.6e-86 280.6 24.7 1e-14 53.7 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS14564.1 - 1.6e-09 36.4 8.4 0.0013 16.9 0.1 4.4 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KOS14564.1 - 1.1e-05 23.8 0.2 0.00046 18.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KOS14564.1 - 2.2e-05 23.3 1.3 1.3 7.6 0.0 3.9 1 1 3 4 4 4 3 Nup133 N terminal like eIF2A PF08662.6 KOS14564.1 - 0.00019 21.1 0.6 0.04 13.6 0.1 3.3 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DAHP_synth_1 PF00793.15 KOS14565.1 - 1.5e-95 318.9 0.1 1.9e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Pterin_bind PF00809.17 KOS14565.1 - 0.061 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme Glucan_synthase PF02364.10 KOS14566.1 - 0 1328.9 0.0 0 1328.1 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KOS14566.1 - 4.6e-37 126.5 0.0 1.4e-36 124.8 0.0 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 ATP-synt_ab PF00006.20 KOS14567.1 - 1.3e-63 214.3 0.0 2.2e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS14567.1 - 1.8e-25 89.5 0.1 3e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS14567.1 - 1.5e-24 85.9 1.2 8.2e-24 83.6 0.6 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.1 KOS14567.1 - 0.0088 16.0 0.2 0.029 14.3 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KOS14567.1 - 0.015 14.5 0.1 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KOS14567.1 - 0.023 14.3 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KOS14567.1 - 0.023 14.3 0.4 1 9.0 0.1 3.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KOS14567.1 - 0.025 13.9 0.1 0.059 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KOS14567.1 - 0.028 14.6 0.0 0.33 11.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KOS14567.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KOS14567.1 - 0.056 13.5 0.0 0.22 11.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain KaiC PF06745.8 KOS14567.1 - 0.067 12.3 0.2 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 KOS14567.1 - 0.079 11.8 0.1 0.079 11.8 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KOS14567.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SCAMP PF04144.8 KOS14568.1 - 9.7e-44 149.3 14.1 1.2e-43 149.0 9.8 1.1 1 0 0 1 1 1 1 SCAMP family DUF4200 PF13863.1 KOS14568.1 - 0.022 14.6 1.0 0.033 14.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4305 PF14146.1 KOS14568.1 - 0.078 12.7 2.6 0.17 11.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) mRNA_triPase PF02940.10 KOS14569.1 - 3.9e-56 190.1 0.0 4.7e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PDZ_2 PF13180.1 KOS14569.1 - 0.09 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 PDZ domain VRR_NUC PF08774.6 KOS14570.1 - 1.1e-18 67.1 0.0 3.6e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 VRR-NUC domain SAP PF02037.22 KOS14570.1 - 2.5e-05 23.6 1.5 2.5e-05 23.6 1.0 1.9 2 0 0 2 2 2 1 SAP domain TMV_coat PF00721.16 KOS14571.1 - 0.011 15.7 0.9 0.014 15.3 0.5 1.3 1 1 0 1 1 1 0 Virus coat protein (TMV like) Pneumo_phosprot PF02478.11 KOS14571.1 - 1.6 8.2 10.9 0.26 10.8 5.1 1.4 1 1 1 2 2 2 0 Pneumovirus phosphoprotein FAA_hydrolase_N PF09298.6 KOS14571.1 - 7.2 6.6 9.4 0.89 9.5 0.9 2.1 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Borrelia_P83 PF05262.6 KOS14572.1 - 2.6 6.1 26.3 3.1 5.9 18.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RNase_H2-Ydr279 PF09468.5 KOS14572.1 - 6.5 5.8 18.7 11 5.1 12.9 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Nop10p PF04135.7 KOS14573.1 - 4.2e-20 71.2 0.2 4.7e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family MMtag PF10159.4 KOS14574.1 - 1.7e-29 101.7 2.3 1.9e-29 101.5 1.6 1.0 1 0 0 1 1 1 1 Kinase phosphorylation protein RNA_pol_Rpb4 PF03874.11 KOS14575.1 - 3.5e-25 88.2 0.1 4.9e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 V-SNARE_C PF12352.3 KOS14577.1 - 1.5e-14 53.8 0.5 2.8e-14 52.9 0.4 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KOS14577.1 - 3.1e-05 23.5 0.8 0.00012 21.6 0.0 2.2 3 0 0 3 3 3 1 Sec20 Mito_fiss_reg PF05308.6 KOS14577.1 - 0.013 14.9 2.2 0.016 14.6 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Syntaxin-18_N PF10496.4 KOS14577.1 - 0.093 12.5 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus CIAPIN1 PF05093.8 KOS14579.1 - 3.3e-29 100.9 1.4 6.4e-29 99.9 1.0 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FYVE PF01363.16 KOS14580.1 - 2.3e-22 78.6 4.2 2.3e-22 78.6 2.9 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KOS14580.1 - 1.3e-10 40.8 6.9 1.3e-10 40.8 4.8 3.8 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 KOS14580.1 - 0.0012 18.8 8.4 0.0012 18.8 5.8 3.4 3 2 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KOS14580.1 - 1.7 8.4 25.8 2 8.2 5.2 3.8 4 0 0 4 4 4 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS14580.1 - 2.1 8.4 26.0 0.049 13.6 6.0 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KOS14580.1 - 2.3 8.2 15.0 0.22 11.5 3.9 3.2 3 1 0 3 3 3 0 FANCL C-terminal domain Syntaxin-18_N PF10496.4 KOS14581.1 - 5.5e-09 35.7 2.2 1.2e-08 34.6 0.0 2.6 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KOS14581.1 - 0.039 13.6 5.5 0.098 12.3 3.8 1.7 1 0 0 1 1 1 0 SNARE domain ISG65-75 PF11727.3 KOS14581.1 - 2.3 7.1 10.9 0.35 9.8 2.8 2.6 3 0 0 3 3 3 0 Invariant surface glycoprotein Peptidase_M20 PF01546.23 KOS14582.1 - 1.2e-12 47.7 0.0 4.6e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ste5 PF11610.3 KOS14582.1 - 0.11 12.0 0.8 9.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Scaffold protein Ste5-Fus5 binding region DUF4505 PF14956.1 KOS14583.1 - 6.6e-06 25.8 0.0 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4505) COX6B PF02297.12 KOS14584.1 - 1e-17 63.9 7.2 1.1e-15 57.3 5.0 2.5 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Gamma-thionin PF00304.15 KOS14584.1 - 0.24 11.4 0.4 0.24 11.4 0.3 1.6 2 0 0 2 2 2 0 Gamma-thionin family OMPdecase PF00215.19 KOS14585.1 - 1.2e-70 237.4 0.0 1.9e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HhH-GPD PF00730.20 KOS14585.1 - 1.4e-15 57.4 0.0 2.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KOS14585.1 - 2.2e-06 27.0 0.0 1.3e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif YEATS PF03366.11 KOS14586.1 - 4.7e-32 109.5 0.0 7.5e-32 108.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family Dus PF01207.12 KOS14587.1 - 9.9e-48 162.5 0.0 1.6e-45 155.2 0.0 2.7 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KOS14587.1 - 8.4e-07 28.5 2.9 0.007 16.0 0.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) YL1_C PF08265.6 KOS14588.1 - 3e-16 58.6 0.7 3e-16 58.6 0.5 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Cut12 PF11500.3 KOS14588.1 - 0.026 14.2 2.2 0.036 13.7 1.5 1.1 1 0 0 1 1 1 0 Spindle pole body formation-associated protein SGS PF05002.10 KOS14589.1 - 1.9e-28 98.0 0.1 3e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KOS14589.1 - 5.5e-11 42.8 0.1 7.5e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.4 KOS14589.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) cNMP_binding PF00027.24 KOS14590.1 - 2.6e-40 136.1 0.0 3.1e-18 65.3 0.0 4.3 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KOS14590.1 - 1.8e-16 60.6 12.9 8.3e-11 42.1 3.0 3.8 3 1 0 4 4 4 2 Patatin-like phospholipase EMP24_GP25L PF01105.19 KOS14591.1 - 7e-47 159.5 0.0 8.1e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ECH PF00378.15 KOS14592.1 - 6.6e-78 261.2 1.4 8.1e-78 260.9 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KOS14592.1 - 0.00032 20.5 0.4 0.0084 15.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 KOS14592.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Alg6_Alg8 PF03155.10 KOS14593.1 - 2.9e-111 372.6 28.4 3.5e-111 372.3 19.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DNA_pol_E_B PF04042.11 KOS14594.1 - 3.4e-40 137.5 0.0 4.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Translin PF01997.11 KOS14595.1 - 4.7e-44 150.3 0.0 5.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Translin family HTH_41 PF14502.1 KOS14595.1 - 0.15 11.6 0.1 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L18e PF00828.14 KOS14597.1 - 7.9e-25 87.6 0.7 1.1e-24 87.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_S13_N PF08069.7 KOS14598.1 - 3.3e-30 103.6 0.3 5.4e-30 103.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KOS14598.1 - 1.7e-20 72.5 0.1 2.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KOS14598.1 - 7.6e-05 22.4 0.1 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 'Paired box' domain HTH_32 PF13565.1 KOS14598.1 - 0.018 15.8 0.3 0.051 14.3 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTHP PF11534.3 KOS14598.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) Histone PF00125.19 KOS14599.1 - 5.3e-27 93.7 0.0 6.8e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS14599.1 - 3e-05 24.0 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Adap_comp_sub PF00928.16 KOS14600.1 - 1.5e-89 299.6 0.0 2.1e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS14600.1 - 1.5e-06 27.9 0.2 2.9e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 KOS14600.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_6 PF14259.1 KOS14601.1 - 3.7e-09 36.4 0.2 2.6e-07 30.5 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS14601.1 - 1e-07 31.4 0.1 0.01 15.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14601.1 - 0.074 12.9 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA PF00627.26 KOS14602.1 - 2.4e-06 27.2 0.5 7.4e-06 25.6 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KOS14602.1 - 5e-06 25.9 0.1 1.2e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 KOS14602.1 - 0.0011 18.4 0.3 0.0065 15.9 0.0 2.6 2 0 0 2 2 2 1 CUE domain Erythro-docking PF09277.6 KOS14602.1 - 0.04 13.6 0.0 12 5.6 0.0 3.0 2 0 0 2 2 2 0 Erythronolide synthase, docking IncA PF04156.9 KOS14602.1 - 2.3 7.7 7.2 4.7 6.7 4.5 1.9 1 1 0 1 1 1 0 IncA protein UIM PF02809.15 KOS14602.1 - 8.6 6.2 8.3 2.3 8.0 1.2 3.3 2 0 0 2 2 2 0 Ubiquitin interaction motif RasGEF PF00617.14 KOS14603.1 - 1.2e-39 136.0 0.1 2e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KOS14603.1 - 8.8e-05 22.5 0.0 0.00022 21.2 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif MMS19_N PF14500.1 KOS14604.1 - 4.3e-64 216.3 0.0 1.8e-49 168.3 0.0 5.1 3 2 1 5 5 5 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KOS14604.1 - 4.6e-51 173.8 0.0 4.7e-50 170.5 0.0 2.5 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 KOS14604.1 - 0.16 12.0 11.2 0.3 11.2 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat Amidohydro_4 PF13147.1 KOS14605.1 - 1.1e-14 55.1 3.7 1.1e-14 55.1 2.6 4.0 2 2 1 3 3 3 1 Amidohydrolase Amidohydro_5 PF13594.1 KOS14605.1 - 8.7e-14 51.0 4.0 8e-11 41.6 0.1 3.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KOS14605.1 - 2.4e-09 37.2 3.2 2.8e-06 27.2 0.0 3.4 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_3 PF07969.6 KOS14605.1 - 8.3e-06 25.2 1.3 0.00034 19.9 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Prominin PF05478.6 KOS14605.1 - 0.78 7.1 0.0 1.1 6.6 0.0 1.1 1 0 0 1 1 1 0 Prominin MBOAT PF03062.14 KOS14606.1 - 9.7e-30 103.7 27.5 2e-29 102.7 19.0 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KOS14606.1 - 0.0028 17.7 1.8 0.01 15.9 1.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Metallophos PF00149.23 KOS14607.1 - 2e-29 102.4 0.0 1e-28 100.0 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 KOS14607.1 - 2.1e-21 75.3 8.2 4.3e-15 55.0 0.8 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS14607.1 - 8.4e-16 56.8 6.1 6.1e-05 22.4 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14607.1 - 3.9e-10 38.8 4.7 0.027 14.3 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 KOS14607.1 - 1e-07 31.8 0.0 4.6e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_16 PF13432.1 KOS14607.1 - 2.7e-07 31.0 2.5 8.3e-05 23.1 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14607.1 - 0.00023 21.5 1.3 0.89 10.3 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS14607.1 - 0.0012 18.8 3.9 0.068 13.3 0.1 3.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14607.1 - 0.0057 16.5 2.3 0.016 15.1 0.2 2.4 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14607.1 - 0.0072 16.6 3.3 0.4 11.0 1.1 2.8 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS14607.1 - 0.015 15.0 0.4 0.22 11.4 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14607.1 - 0.026 14.9 2.2 11 6.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KOS14607.1 - 0.068 12.9 1.1 15 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Metallophos_2 PF12850.2 KOS14607.1 - 0.097 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SHS2_Rpb7-N PF03876.12 KOS14608.1 - 4.3e-15 55.5 0.0 6.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KOS14608.1 - 0.00024 21.1 0.0 0.00058 19.9 0.0 1.5 1 1 0 1 1 1 1 S1 RNA binding domain Glyco_transf_20 PF00982.16 KOS14609.1 - 7e-154 512.8 0.2 9.4e-154 512.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KOS14609.1 - 9.2e-21 73.8 0.0 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase BAR PF03114.13 KOS14610.1 - 1.6e-45 155.4 0.4 2e-45 155.0 0.3 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KOS14610.1 - 0.029 13.7 2.7 0.12 11.7 1.9 2.0 1 1 0 1 1 1 0 Arfaptin-like domain Pyridoxal_deC PF00282.14 KOS14611.1 - 4.8e-67 225.9 0.0 6.5e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KOS14611.1 - 1.6e-06 27.5 0.0 2.6e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KOS14611.1 - 6.5e-05 21.8 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_60s PF00428.14 KOS14611.1 - 0.11 12.8 3.9 0.28 11.6 2.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Methyltransf_16 PF10294.4 KOS14612.1 - 5.5e-14 51.9 0.0 2.1e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 KOS14612.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KOS14612.1 - 0.0014 19.2 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14612.1 - 0.059 12.9 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14612.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain RasGAP PF00616.14 KOS14613.1 - 7.7e-07 28.9 0.0 1.7e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KOS14613.1 - 0.078 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Adaptin_N PF01602.15 KOS14614.1 - 4.6e-97 325.5 12.5 5.5e-97 325.2 8.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KOS14614.1 - 1.8e-18 66.5 0.0 3.9e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT PF02985.17 KOS14614.1 - 0.00029 20.6 3.3 1.7 8.9 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Nop14 PF04147.7 KOS14615.1 - 4.7e-223 742.7 22.7 5.5e-223 742.4 15.7 1.0 1 0 0 1 1 1 1 Nop14-like family PH PF00169.24 KOS14616.1 - 3.2e-06 27.2 0.0 1.5e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 KOS14616.1 - 4.2e-05 23.6 0.1 0.0028 17.8 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KOS14616.1 - 0.017 15.3 1.4 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain zf-RING_2 PF13639.1 KOS14617.1 - 6.7e-10 38.6 11.5 1.1e-09 37.9 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS14617.1 - 2.4e-06 27.1 10.4 3.6e-06 26.5 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KOS14617.1 - 2.9e-06 27.2 2.6 5.5e-06 26.4 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KOS14617.1 - 3.1e-05 23.5 8.2 4.6e-05 22.9 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS14617.1 - 0.0003 20.7 10.9 0.00047 20.1 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS14617.1 - 0.089 12.4 9.8 0.15 11.7 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS14617.1 - 0.6 9.9 6.9 1.5 8.7 4.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger NT-C2 PF10358.4 KOS14618.1 - 8.8e-08 31.7 0.0 0.001 18.5 0.0 3.2 3 0 0 3 3 3 3 N-terminal C2 in EEIG1 and EHBP1 proteins Pyr_redox PF00070.22 KOS14619.1 - 1.1e-15 57.8 0.1 7.5e-12 45.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS14619.1 - 1.9e-08 34.4 0.0 0.0021 17.9 0.0 3.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS14619.1 - 0.00013 22.1 0.0 1 9.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 KOS14619.1 - 0.0099 15.6 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS14619.1 - 0.0099 15.4 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thi4 PF01946.12 KOS14619.1 - 0.046 12.8 0.0 0.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Peptidase_S9 PF00326.16 KOS14619.1 - 0.06 12.5 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KOS14619.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.19 KOS14619.1 - 0.1 11.4 0.1 1.3 7.8 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KOS14619.1 - 0.15 10.6 0.0 0.69 8.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Abhydrolase_5 PF12695.2 KOS14620.1 - 0.0077 15.9 0.2 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS14620.1 - 0.012 15.4 2.9 0.029 14.2 1.5 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family TAP_C PF03943.8 KOS14621.1 - 5.8e-12 44.8 0.0 1.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 KOS14621.1 - 2e-07 31.3 0.4 7.4e-07 29.5 0.3 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 KOS14621.1 - 3.8e-06 26.3 2.8 9.6e-05 21.9 1.3 2.8 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KOS14621.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 KOS14621.1 - 0.015 15.3 1.5 4.6 7.8 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 KOS14621.1 - 0.017 14.8 2.1 0.081 12.6 1.4 2.2 1 1 0 1 1 1 0 Leucine rich repeat Peptidase_M20 PF01546.23 KOS14622.1 - 3.8e-25 88.4 0.0 5.7e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KOS14622.1 - 2.2e-11 43.4 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KOS14622.1 - 0.0086 15.8 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Tau95 PF09734.4 KOS14623.1 - 4.6e-47 160.8 0.0 6.1e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CDC45 PF02724.9 KOS14624.1 - 5.4 4.9 6.7 8.8 4.2 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_11 PF13414.1 KOS14625.1 - 1.4e-26 91.8 10.0 2.2e-05 24.0 0.0 7.2 7 2 0 7 7 6 6 TPR repeat TPR_16 PF13432.1 KOS14625.1 - 3.8e-20 72.0 16.6 4.6e-05 23.9 1.0 8.2 5 2 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14625.1 - 2.5e-18 64.9 16.6 0.0076 16.7 0.9 10.7 6 2 5 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14625.1 - 2.8e-18 64.2 16.0 0.071 13.0 0.0 10.7 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14625.1 - 3.6e-15 56.0 8.8 1.3e-07 31.8 0.0 7.3 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS14625.1 - 1.2e-13 49.9 8.2 0.018 14.5 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 KOS14625.1 - 4.2e-11 42.5 10.9 8 7.1 0.0 9.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14625.1 - 4.7e-10 39.2 14.1 0.039 13.8 0.0 7.6 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS14625.1 - 3.3e-09 35.8 4.0 1.5 8.8 0.0 8.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS14625.1 - 1.3e-07 31.2 0.3 1.5 9.1 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KOS14625.1 - 7.9e-07 28.8 21.4 0.0048 16.7 0.3 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS14625.1 - 1.1e-06 28.6 7.6 0.06 13.4 0.0 5.9 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KOS14625.1 - 1.2e-06 27.8 4.4 0.00049 19.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KOS14625.1 - 4.6e-05 22.3 0.2 0.21 10.2 0.0 3.2 3 0 0 3 3 3 2 N-acetyltransferase B complex (NatB) non catalytic subunit NARP1 PF12569.3 KOS14625.1 - 0.00056 18.7 1.9 0.23 10.1 0.0 3.3 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 KOS14625.1 - 0.0012 18.4 6.7 1.8 8.5 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KOS14625.1 - 0.0016 18.4 6.7 0.27 11.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KOS14625.1 - 0.0047 17.1 0.8 0.56 10.4 0.1 3.2 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation Arm PF00514.18 KOS14626.1 - 0.14 11.9 0.1 0.14 11.9 0.1 8.2 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KOS14627.1 - 1.9e-12 47.1 0.8 6.4e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF1780 PF08682.5 KOS14628.1 - 0.048 13.1 1.6 0.073 12.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1780) DUF572 PF04502.8 KOS14628.1 - 0.083 12.0 5.7 0.13 11.4 3.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) COBRA1 PF06209.8 KOS14628.1 - 0.14 10.7 0.3 0.2 10.2 0.2 1.2 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) UnbV_ASPIC PF07593.7 KOS14629.1 - 0.087 12.5 0.2 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 ASPIC and UnbV Nop14 PF04147.7 KOS14630.1 - 0.17 9.7 13.4 0.35 8.7 9.3 1.4 1 0 0 1 1 1 0 Nop14-like family Cep57_CLD PF14073.1 KOS14630.1 - 0.56 10.0 15.0 0.18 11.6 3.1 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF1949 PF09186.6 KOS14630.1 - 0.67 9.5 5.3 5.5 6.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Tropomyosin_1 PF12718.2 KOS14630.1 - 0.83 9.4 12.9 0.065 13.0 5.0 2.0 2 0 0 2 2 2 0 Tropomyosin like PPR_3 PF13812.1 KOS14631.1 - 9.4e-17 59.8 8.9 0.0085 16.3 0.0 8.2 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KOS14631.1 - 9.2e-15 54.3 0.4 0.006 16.5 0.0 6.1 6 1 0 6 6 6 4 PPR repeat family PPR_1 PF12854.2 KOS14631.1 - 2.2e-08 33.4 0.4 0.00019 20.8 0.0 4.8 6 0 0 6 6 6 1 PPR repeat PPR PF01535.15 KOS14631.1 - 5.6e-08 32.2 3.4 0.086 12.8 0.0 6.2 7 0 0 7 7 7 1 PPR repeat ECSIT PF06239.6 KOS14631.1 - 0.00053 18.9 0.0 0.012 14.4 0.0 2.3 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.1 KOS14631.1 - 0.095 13.3 3.8 19 6.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14631.1 - 1.4 9.7 10.8 12 6.9 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat PH PF00169.24 KOS14632.1 - 0.00041 20.5 0.1 0.78 9.9 0.0 2.7 2 0 0 2 2 2 2 PH domain F-box-like PF12937.2 KOS14633.1 - 1.4e-13 50.2 1.7 3.3e-13 49.1 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS14633.1 - 8.6e-10 38.0 0.3 4.2e-09 35.8 0.2 2.2 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 KOS14633.1 - 5.1e-06 26.0 1.8 6.6e-06 25.6 0.3 1.8 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 KOS14633.1 - 0.0011 19.4 5.0 0.0034 17.8 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KOS14633.1 - 0.0016 17.5 4.0 0.0044 16.1 2.8 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14633.1 - 0.014 15.2 0.9 6.2 7.0 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3677 PF12432.3 KOS14633.1 - 0.059 13.8 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) TPR_1 PF00515.23 KOS14633.1 - 0.11 12.2 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KOS14633.1 - 0.31 11.4 2.1 0.65 10.3 0.4 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Sds3 PF08598.6 KOS14634.1 - 3.9e-13 49.4 3.6 3.9e-13 49.4 2.5 1.5 1 1 1 2 2 2 1 Sds3-like ESCRT-II PF05871.7 KOS14635.1 - 6.6e-36 123.2 0.0 1.3e-35 122.3 0.0 1.4 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3602 PF12223.3 KOS14636.1 - 2.8e-14 53.2 17.6 5.6e-09 36.2 3.2 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Protamine_P2 PF00841.14 KOS14636.1 - 0.45 11.1 5.2 1 9.9 3.6 1.6 1 0 0 1 1 1 0 Sperm histone P2 SAP30_Sin3_bdg PF13867.1 KOS14637.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Fis1_TPR_C PF14853.1 KOS14638.1 - 1.1e-22 79.6 1.3 1.8e-22 78.9 0.9 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KOS14638.1 - 4.6e-15 54.6 0.0 7.8e-15 53.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 KOS14638.1 - 0.017 15.7 0.3 0.036 14.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14638.1 - 0.023 14.5 1.7 0.025 14.4 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat COPI_C PF06957.6 KOS14638.1 - 0.034 12.7 0.1 0.055 12.0 0.0 1.3 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus TPR_19 PF14559.1 KOS14638.1 - 0.056 13.7 0.3 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Leu_leader PF08054.6 KOS14638.1 - 1.1 8.9 3.7 0.88 9.2 0.4 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide Gln-synt_C PF00120.19 KOS14639.1 - 2.1e-56 190.9 0.0 2.5e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KOS14639.1 - 4.4e-18 64.6 0.0 6.8e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FF PF01846.14 KOS14640.1 - 1.6e-25 88.7 0.6 2.7e-09 36.8 0.0 5.6 5 0 0 5 5 5 5 FF domain WW PF00397.21 KOS14640.1 - 1.3e-09 37.6 13.9 3.2e-05 23.7 2.8 2.8 2 0 0 2 2 2 2 WW domain Sds3 PF08598.6 KOS14641.1 - 1.4e-17 63.8 0.9 1.4e-17 63.8 0.6 1.9 2 1 0 2 2 2 1 Sds3-like DUF3275 PF11679.3 KOS14642.1 - 0.098 12.2 2.5 0.074 12.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) RRM_1 PF00076.17 KOS14643.1 - 2.7e-20 71.7 0.0 5.8e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14643.1 - 6.3e-16 58.1 0.0 3.6e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14643.1 - 9.5e-11 41.3 0.0 0.0052 16.6 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.24 KOS14644.1 - 3.7e-44 150.8 0.0 5.4e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS14644.1 - 5.9e-12 45.6 0.0 3.4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nup35_RRM PF05172.8 KOS14645.1 - 1.3e-09 37.7 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KOS14645.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L21p PF00829.16 KOS14647.1 - 3.9e-08 33.3 0.1 1.8e-06 27.9 0.1 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Ank_4 PF13637.1 KOS14648.1 - 7.7e-18 64.4 1.6 2.3e-12 47.0 0.2 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS14648.1 - 2.8e-17 61.5 1.5 2.6e-07 30.0 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KOS14648.1 - 2.8e-17 62.8 5.5 4e-16 59.1 2.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KOS14648.1 - 2.4e-15 56.1 4.8 3.6e-06 27.0 0.3 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS14648.1 - 6.3e-13 47.6 0.5 8.9e-05 22.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Sas10_Utp3 PF04000.10 KOS14649.1 - 2.5e-10 40.3 0.3 6.1e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ist1 PF03398.9 KOS14651.1 - 1.1e-52 177.8 4.5 1.3e-52 177.5 3.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PQ-loop PF04193.9 KOS14652.1 - 6.2e-19 67.3 11.4 1.1e-10 40.8 3.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF2781 PF10914.3 KOS14652.1 - 0.022 14.5 0.7 0.06 13.1 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) BRCA-2_OB1 PF09103.5 KOS14653.1 - 3.4e-28 97.7 0.0 5.3e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 KOS14653.1 - 9.7e-07 28.5 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 BRCA2, helical Cyt-b5 PF00173.23 KOS14654.1 - 4.2e-13 48.8 0.4 6.5e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 3HCDH_N PF02737.13 KOS14655.1 - 6.3e-56 188.8 1.8 8.9e-56 188.3 1.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KOS14655.1 - 4.3e-31 107.1 0.0 1.1e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 KOS14655.1 - 0.00054 19.0 0.6 0.00094 18.2 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 KOS14655.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 ThiF family NAD_Gly3P_dh_N PF01210.18 KOS14655.1 - 0.0013 18.5 1.6 0.0035 17.1 1.1 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KOS14655.1 - 0.0044 16.4 1.9 0.028 13.7 1.3 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KOS14655.1 - 0.0045 16.5 0.6 0.0076 15.8 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1104 PF06518.6 KOS14655.1 - 0.0082 16.2 0.3 1.1 9.4 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) NAD_binding_2 PF03446.10 KOS14655.1 - 0.011 15.6 4.0 0.75 9.6 2.8 2.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KOS14655.1 - 0.045 14.1 3.1 0.9 10.0 2.2 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 KOS14655.1 - 0.083 13.3 0.1 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L5_C PF00673.16 KOS14656.1 - 1.5e-07 31.0 0.0 5.8e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KOS14656.1 - 0.031 14.0 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L5 Helicase_C_2 PF13307.1 KOS14657.1 - 2.8e-56 190.0 0.0 6.2e-56 188.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KOS14657.1 - 3.9e-44 150.0 0.0 5.7e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.11 KOS14657.1 - 0.0016 17.6 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein DEAD PF00270.24 KOS14657.1 - 0.003 17.0 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 KOS14657.1 - 0.013 14.2 0.0 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 KOS14657.1 - 0.046 13.5 0.1 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS14657.1 - 0.17 12.0 0.2 24 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain SIS PF01380.17 KOS14658.1 - 2.3e-58 195.4 0.2 1.6e-33 115.0 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KOS14658.1 - 2.8e-26 92.0 0.0 6.1e-19 67.9 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KOS14658.1 - 6.8e-21 74.6 0.0 1.7e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KOS14658.1 - 2.3e-14 53.1 0.0 8.4e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KOS14658.1 - 1.5e-07 30.3 0.0 2.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KOS14658.1 - 0.0019 17.9 0.0 0.027 14.1 0.0 2.5 2 0 0 2 2 2 1 SIS domain Plasmid_Txe PF06769.8 KOS14658.1 - 0.0081 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Plasmid encoded toxin Txe TFIIIC_sub6 PF10419.4 KOS14659.1 - 7.3e-10 38.1 0.0 1.3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit HCNGP PF07818.8 KOS14660.1 - 6.1e-15 55.0 0.0 9.4e-15 54.4 0.0 1.4 1 1 0 1 1 1 1 HCNGP-like protein CPSF100_C PF13299.1 KOS14661.1 - 1.4e-24 87.0 0.4 3.4e-19 69.6 0.0 3.2 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KOS14661.1 - 1.3e-17 63.8 0.0 8.5e-17 61.2 0.0 2.4 3 0 0 3 3 3 1 Beta-Casp domain Complex1_LYR_1 PF13232.1 KOS14664.1 - 7.7e-16 58.0 0.8 1.8e-15 56.8 0.6 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KOS14664.1 - 1.3e-08 34.5 2.2 2.3e-08 33.7 1.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) GvpO PF05800.6 KOS14664.1 - 0.097 12.5 0.3 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO HPP PF04982.8 KOS14665.1 - 0.015 15.1 2.5 0.02 14.6 1.7 1.3 1 0 0 1 1 1 0 HPP family DUF979 PF06166.7 KOS14665.1 - 0.028 13.3 0.5 0.031 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) NMO PF03060.10 KOS14666.1 - 3.2e-45 154.7 0.5 8.4e-45 153.3 0.3 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KOS14666.1 - 0.0017 17.2 0.0 0.43 9.4 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KOS14666.1 - 0.0061 15.4 0.3 0.013 14.3 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KOS14666.1 - 0.62 8.9 2.5 2.7 6.8 1.7 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase RCC1 PF00415.13 KOS14667.1 - 2.8e-15 56.2 7.9 0.00043 20.4 0.1 6.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS14667.1 - 6.9e-07 28.7 2.6 6.9e-07 28.7 1.8 5.3 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat IncA PF04156.9 KOS14668.1 - 0.012 15.2 1.9 0.012 15.2 1.3 2.7 3 0 0 3 3 3 0 IncA protein Cep57_MT_bd PF06657.8 KOS14668.1 - 0.041 13.8 16.0 0.05 13.5 3.1 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.6 KOS14668.1 - 0.055 13.2 0.3 0.055 13.2 0.2 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.6 KOS14668.1 - 0.31 10.3 5.4 3.9 6.8 0.3 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Hemerythrin PF01814.18 KOS14668.1 - 0.58 10.3 14.2 0.45 10.6 0.1 3.0 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain BRE1 PF08647.6 KOS14668.1 - 0.69 9.9 24.0 0.05 13.5 3.8 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TBPIP PF07106.8 KOS14668.1 - 1.1 8.8 23.6 0.043 13.3 4.0 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 KOS14668.1 - 2.5 6.9 27.4 0.084 11.8 7.2 2.6 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 KOS14669.1 - 9.4e-25 85.5 0.1 5.6e-07 29.2 0.1 5.0 5 1 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 KOS14669.1 - 0.0011 18.6 0.1 2.5 7.9 0.0 3.3 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region RRM_1 PF00076.17 KOS14670.1 - 2.3e-11 43.1 0.0 3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14670.1 - 4.4e-08 32.9 0.0 5.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14670.1 - 8.2e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS14670.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 GATase PF00117.23 KOS14671.1 - 0.0019 17.6 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I FYVE_2 PF02318.11 KOS14672.1 - 0.12 12.2 0.3 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger AAA PF00004.24 KOS14673.1 - 9.6e-85 281.4 0.0 6.8e-42 142.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS14673.1 - 2e-14 53.9 0.5 7.4e-08 32.5 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KOS14673.1 - 1.1e-11 44.6 0.2 7.4e-06 25.7 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KOS14673.1 - 1.3e-10 40.7 0.0 3.5e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS14673.1 - 2.5e-10 40.5 0.1 5.4e-05 23.3 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KOS14673.1 - 4e-08 34.1 0.0 0.00094 19.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 KOS14673.1 - 2.2e-07 29.9 0.0 0.0064 15.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 KOS14673.1 - 2.6e-07 30.5 0.0 0.00071 19.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KOS14673.1 - 4.6e-07 29.1 0.0 0.00036 19.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KOS14673.1 - 9.4e-07 28.9 0.0 0.0047 17.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 KOS14673.1 - 1.4e-06 28.1 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS14673.1 - 2.6e-06 27.1 3.7 0.0014 18.3 0.0 3.8 4 0 0 4 4 3 2 Part of AAA domain AAA_2 PF07724.9 KOS14673.1 - 2.6e-06 27.4 0.0 0.013 15.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KOS14673.1 - 9e-06 25.4 0.2 0.0022 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KOS14673.1 - 2.8e-05 24.1 0.4 0.07 13.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 KOS14673.1 - 8.2e-05 21.8 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS14673.1 - 8.9e-05 21.9 0.0 0.08 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.6 KOS14673.1 - 0.00019 21.0 0.0 0.53 9.9 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KOS14673.1 - 0.00036 20.2 0.0 0.63 9.6 0.0 3.3 2 2 2 4 4 4 1 Archaeal ATPase AAA_25 PF13481.1 KOS14673.1 - 0.00042 19.7 4.7 0.091 12.1 0.1 3.5 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 KOS14673.1 - 0.00046 19.8 0.1 0.23 11.1 0.0 3.7 4 0 0 4 4 4 1 NACHT domain AAA_18 PF13238.1 KOS14673.1 - 0.00046 20.4 0.0 0.036 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KOS14673.1 - 0.00089 19.3 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.10 KOS14673.1 - 0.0014 17.3 0.0 0.046 12.4 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KOS14673.1 - 0.0037 16.2 0.0 0.094 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 KOS14673.1 - 0.0058 16.2 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KOS14673.1 - 0.012 14.7 0.1 2.7 7.0 0.0 2.6 3 0 0 3 3 2 0 KaiC ABC_tran PF00005.22 KOS14673.1 - 0.02 15.2 0.0 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 KOS14673.1 - 0.021 14.4 0.1 0.47 10.0 0.0 2.5 2 1 1 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KOS14673.1 - 0.026 14.1 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KOS14673.1 - 0.036 13.5 0.0 3.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 KOS14673.1 - 0.058 12.6 0.0 0.72 9.0 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein DAP3 PF10236.4 KOS14673.1 - 0.064 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 KOS14673.1 - 0.066 12.9 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 KOS14673.1 - 0.11 11.3 0.0 0.63 8.8 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ribosomal_S4 PF00163.14 KOS14674.1 - 8.1e-28 96.6 0.4 1.3e-27 95.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KOS14674.1 - 3.8e-13 48.6 0.5 3.8e-13 48.6 0.3 2.3 3 0 0 3 3 3 1 S4 domain HMG_CoA_synt_N PF01154.12 KOS14675.1 - 1.6e-86 288.2 0.1 2.5e-86 287.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 KOS14675.1 - 1e-80 271.2 0.1 1.4e-80 270.8 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 KOS14675.1 - 0.00015 21.6 0.0 0.0051 16.7 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KOS14675.1 - 0.028 14.0 0.3 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Snf7 PF03357.16 KOS14676.1 - 1.3e-43 148.3 19.3 1.6e-43 148.0 13.4 1.0 1 0 0 1 1 1 1 Snf7 DUF4559 PF15112.1 KOS14676.1 - 0.0041 16.3 7.1 0.0054 15.9 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) DUF1569 PF07606.6 KOS14676.1 - 0.069 13.0 0.7 0.069 13.0 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1569) Mod_r PF07200.8 KOS14676.1 - 0.097 12.5 12.7 5.3 6.9 7.8 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2746 PF10874.3 KOS14676.1 - 0.2 11.8 0.4 0.2 11.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) NPV_P10 PF05531.7 KOS14676.1 - 0.65 10.2 5.2 1.8 8.8 0.6 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein THP2 PF09432.5 KOS14676.1 - 0.95 9.3 7.3 0.41 10.5 2.0 2.3 1 1 0 2 2 2 0 Tho complex subunit THP2 AAA_23 PF13476.1 KOS14676.1 - 1.3 9.3 6.3 1.8 8.8 4.3 1.3 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 KOS14676.1 - 4.4 6.9 14.2 2.9 7.5 7.2 2.0 1 1 1 2 2 2 0 Mnd1 family DUF848 PF05852.6 KOS14676.1 - 4.5 7.1 11.9 5 6.9 6.5 2.3 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HeLo PF14479.1 KOS14676.1 - 5 6.8 13.0 1.3 8.7 1.7 2.1 1 1 1 2 2 2 0 Prion-inhibition and propagation Atg14 PF10186.4 KOS14676.1 - 7.1 5.4 12.8 23 3.7 8.8 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KOS14676.1 - 7.8 4.7 9.9 20 3.4 6.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Tim17 PF02466.14 KOS14677.1 - 9.1e-19 67.7 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Nup84_Nup100 PF04121.8 KOS14678.1 - 3.9e-98 328.9 0.0 4.6e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 CorA PF01544.13 KOS14680.1 - 1.4e-14 53.8 6.9 6.2e-06 25.4 0.9 3.2 2 1 1 3 3 3 3 CorA-like Mg2+ transporter protein PhoD PF09423.5 KOS14681.1 - 1.6e-41 142.3 0.1 1.1e-40 139.5 0.1 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase HATPase_c PF02518.21 KOS14682.1 - 1.4e-18 66.6 0.2 3.2e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KOS14682.1 - 1.4e-17 63.7 0.0 6.4e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KOS14682.1 - 1.2e-15 57.2 0.1 3.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain U3_assoc_6 PF08640.6 KOS14683.1 - 1.7e-19 69.3 2.2 7.8e-19 67.2 0.6 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Nucleoplasmin PF03066.10 KOS14683.1 - 0.13 11.7 7.8 4.8 6.6 3.9 2.6 2 0 0 2 2 2 0 Nucleoplasmin RTA1 PF04479.8 KOS14684.1 - 3.3e-27 95.4 6.0 4.1e-27 95.1 4.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Frag1 PF10277.4 KOS14684.1 - 0.015 14.7 4.8 0.02 14.4 3.3 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Cation_ATPase_C PF00689.16 KOS14684.1 - 0.4 10.1 6.5 0.58 9.6 4.5 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Nucleoporin_C PF03177.9 KOS14685.1 - 7.4e-70 236.0 0.2 9.8e-70 235.6 0.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KOS14685.1 - 9.2e-42 143.2 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like DUF2370 PF10176.4 KOS14686.1 - 0.23 10.7 6.0 0.58 9.4 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF605 PF04652.11 KOS14686.1 - 1 8.6 17.5 1.4 8.2 12.1 1.1 1 0 0 1 1 1 0 Vta1 like XPG_I PF00867.13 KOS14688.1 - 1.1e-11 44.5 0.0 3.1e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KOS14688.1 - 2.1e-07 31.1 0.0 4.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain SMC_N PF02463.14 KOS14688.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PHD PF00628.24 KOS14689.1 - 6.5e-07 28.9 19.8 1.1e-06 28.2 13.7 1.4 1 0 0 1 1 1 1 PHD-finger Zn_clus PF00172.13 KOS14690.1 - 2e-05 24.3 7.6 2e-05 24.3 5.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIP5K PF01504.13 KOS14691.1 - 9e-62 208.4 0.0 1.7e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KOS14691.1 - 5.6e-20 71.4 0.1 8.7e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KOS14691.1 - 4.8e-18 64.8 9.1 1.6e-17 63.1 6.3 2.0 1 0 0 1 1 1 1 FYVE zinc finger VHS PF00790.14 KOS14692.1 - 2.8e-39 133.9 0.0 9.3e-39 132.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KOS14692.1 - 9.5e-17 60.8 2.7 9.6e-17 60.8 0.5 2.0 2 0 0 2 2 2 1 GAT domain Erp_C PF06780.6 KOS14692.1 - 0.0023 17.7 1.3 0.005 16.6 0.6 1.8 1 1 1 2 2 2 2 Erp protein C-terminus Gag_spuma PF03276.9 KOS14692.1 - 0.08 11.2 1.7 0.11 10.8 1.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4262 PF14081.1 KOS14692.1 - 0.12 12.5 0.1 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) RBM39linker PF15519.1 KOS14692.1 - 0.14 12.4 1.0 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Pkinase PF00069.20 KOS14693.1 - 1.4e-71 240.7 0.0 3.3e-71 239.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14693.1 - 6.6e-36 123.6 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14693.1 - 0.00026 20.0 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS14693.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 4.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family Rxt3 PF08642.5 KOS14694.1 - 7e-19 68.1 0.0 7e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KOS14694.1 - 0.006 16.5 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 LCCL domain DUF3074 PF11274.3 KOS14695.1 - 0.064 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) DSPc PF00782.15 KOS14696.1 - 5.4e-18 64.8 0.0 1.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS14696.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BP28CT PF08146.7 KOS14697.1 - 2.2e-23 82.6 0.2 1.8e-22 79.6 0.2 2.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KOS14697.1 - 1.3e-13 50.9 6.8 1.3e-13 50.9 4.7 8.1 8 2 1 9 9 9 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KOS14697.1 - 2.4 8.4 12.9 0.33 11.1 0.7 5.5 4 0 0 4 4 4 0 HEAT repeat HLH PF00010.21 KOS14698.1 - 3.8e-09 36.0 0.0 8.6e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hint_2 PF13403.1 KOS14698.1 - 0.00093 19.1 0.4 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 Hint domain DUF4613 PF15390.1 KOS14698.1 - 0.32 9.1 3.1 0.4 8.8 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PEP-utilisers_N PF05524.8 KOS14698.1 - 0.34 10.7 2.7 0.3 10.8 0.3 2.0 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal TRAPPC9-Trs120 PF08626.6 KOS14699.1 - 1.3e-70 238.0 0.0 1.7e-53 181.3 0.0 3.5 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mit_ribos_Mrp51 PF11709.3 KOS14700.1 - 2.1e-18 66.6 0.4 5.2e-18 65.3 0.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit eIF-3_zeta PF05091.7 KOS14700.1 - 0.073 11.6 2.7 0.33 9.5 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) She9_MDM33 PF05546.6 KOS14701.1 - 1.7e-56 191.0 10.4 2.1e-56 190.7 7.2 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family IncA PF04156.9 KOS14701.1 - 0.016 14.8 10.6 0.43 10.1 0.2 3.2 2 1 1 3 3 3 0 IncA protein Amidase PF01425.16 KOS14701.1 - 0.1 11.4 2.7 0.15 10.8 1.9 1.2 1 0 0 1 1 1 0 Amidase Peptidase_M13_N PF05649.8 KOS14702.1 - 2e-97 326.6 0.0 2.7e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KOS14702.1 - 1.5e-56 190.8 0.0 2.5e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 3H PF02829.9 KOS14702.1 - 0.045 13.7 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 3H domain Peptidase_M13_N PF05649.8 KOS14703.1 - 2.9e-86 289.9 0.0 3.6e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KOS14703.1 - 1.3e-55 187.8 0.0 2e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 tRNA-synt_2 PF00152.15 KOS14704.1 - 1.9e-44 151.8 0.0 3.2e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ECH_C PF13766.1 KOS14704.1 - 7.6e-19 68.0 0.0 4.7e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KOS14704.1 - 2.6e-13 49.6 0.0 1.9e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family tRNA_anti-codon PF01336.20 KOS14704.1 - 2e-05 24.3 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FRG1 PF06229.7 KOS14704.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FRG1-like family Ferric_reduct PF01794.14 KOS14705.1 - 2.5e-14 53.4 12.8 2.5e-14 53.4 8.9 3.2 2 2 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KOS14705.1 - 5.3e-13 48.7 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KOS14705.1 - 9.4e-13 48.3 0.0 5.1e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NUC173 PF08161.7 KOS14706.1 - 3.2e-38 131.0 0.1 1.3e-37 129.0 0.0 2.1 2 0 0 2 2 2 1 NUC173 domain CAS_CSE1 PF03378.10 KOS14706.1 - 0.00061 18.2 0.0 0.0013 17.1 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus zf-RING_4 PF14570.1 KOS14707.1 - 2e-21 75.3 11.5 3.3e-21 74.5 8.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KOS14707.1 - 1.9e-05 24.2 9.2 3.3e-05 23.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KOS14707.1 - 0.00065 19.4 2.6 0.0012 18.6 1.8 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 KOS14707.1 - 0.00093 19.0 0.0 0.0097 15.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS14707.1 - 0.0011 18.6 0.0 0.0044 16.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 KOS14707.1 - 0.0085 16.0 12.9 0.014 15.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KOS14707.1 - 0.015 15.0 4.2 0.037 13.7 2.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1510 PF07423.6 KOS14708.1 - 0.016 14.5 28.6 0.019 14.3 19.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KOS14708.1 - 0.017 12.9 9.6 0.016 12.9 6.7 1.0 1 0 0 1 1 1 0 Ycf1 SprA-related PF12118.3 KOS14708.1 - 0.022 14.1 17.7 0.024 13.9 12.3 1.0 1 0 0 1 1 1 0 SprA-related family NAM-associated PF14303.1 KOS14708.1 - 0.19 12.0 26.0 0.24 11.6 18.0 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FLO_LFY PF01698.11 KOS14708.1 - 0.26 10.0 14.0 0.29 9.9 9.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SDA1 PF05285.7 KOS14708.1 - 0.58 9.3 31.1 0.61 9.3 21.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KOS14708.1 - 0.63 7.9 24.1 0.77 7.7 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.1 KOS14708.1 - 0.96 7.5 3.4 1.3 7.1 2.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.7 KOS14708.1 - 1.2 8.9 14.7 1.4 8.8 10.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 KOS14708.1 - 2.3 8.0 21.7 2.7 7.8 15.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.4 KOS14708.1 - 2.4 6.9 21.0 2.9 6.6 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3357 PF11837.3 KOS14708.1 - 2.7 7.8 6.5 24 4.8 4.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) PPP4R2 PF09184.6 KOS14708.1 - 3.2 7.2 28.9 3.7 7.0 20.0 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 KOS14708.1 - 4 5.8 13.0 4.6 5.6 9.0 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 KOS14708.1 - 4.6 4.7 14.3 4.6 4.7 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 KOS14708.1 - 5 4.9 31.4 5.3 4.8 21.8 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 KOS14708.1 - 7.2 6.4 23.2 7.9 6.3 16.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Neur_chan_memb PF02932.11 KOS14708.1 - 7.3 6.4 10.7 8.4 6.1 7.1 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 KOS14708.1 - 9.6 5.0 15.6 11 4.8 10.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CBFD_NFYB_HMF PF00808.18 KOS14709.1 - 2.5e-08 33.8 0.3 5.1e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIN_3 PF13470.1 KOS14709.1 - 0.025 15.2 0.6 0.038 14.6 0.4 1.3 1 0 0 1 1 1 0 PIN domain Myb_CC_LHEQLE PF14379.1 KOS14709.1 - 0.046 13.3 0.2 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif MSP1_C PF07462.6 KOS14709.1 - 0.34 9.2 7.3 0.53 8.6 5.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus K_channel_TID PF07941.6 KOS14709.1 - 0.54 10.5 21.2 0.069 13.3 11.5 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DDRGK PF09756.4 KOS14709.1 - 0.58 9.5 3.0 0.85 8.9 2.1 1.2 1 0 0 1 1 1 0 DDRGK domain DUF3138 PF11336.3 KOS14709.1 - 1.3 7.1 5.8 1.6 6.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1682 PF07946.9 KOS14709.1 - 1.4 7.6 3.6 1.7 7.3 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Bromodomain PF00439.20 KOS14710.1 - 4.5e-42 141.8 1.9 4.3e-20 71.4 0.1 2.3 2 0 0 2 2 2 2 Bromodomain Adaptin_N PF01602.15 KOS14711.1 - 1.3e-84 284.4 8.4 2e-84 283.7 5.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KOS14711.1 - 6.2e-07 29.4 3.6 0.011 15.6 0.1 3.7 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KOS14711.1 - 7.8e-07 29.2 8.3 0.018 15.3 0.2 5.6 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.17 KOS14711.1 - 0.00031 20.5 4.0 0.42 10.8 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat DUF732 PF05305.9 KOS14711.1 - 0.067 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Arm PF00514.18 KOS14711.1 - 0.18 11.6 2.9 16 5.4 0.1 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KOS14711.1 - 1.1 9.7 13.8 13 6.3 0.1 5.9 6 1 1 7 7 7 0 HEAT-like repeat Tim54 PF11711.3 KOS14712.1 - 1.4e-57 195.0 0.0 8.3e-57 192.5 0.0 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SH3BP5 PF05276.9 KOS14712.1 - 0.0097 15.2 4.6 0.67 9.2 0.0 2.8 3 0 0 3 3 3 2 SH3 domain-binding protein 5 (SH3BP5) Bac_rhamnosid PF05592.6 KOS14712.1 - 0.069 11.3 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase SAM_2 PF07647.12 KOS14713.1 - 3.7e-10 39.4 0.5 9.3e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KOS14713.1 - 1.2e-06 28.5 0.1 3.8e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NDK PF00334.14 KOS14714.1 - 2e-52 176.5 0.0 2.6e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ctf8 PF09696.5 KOS14715.1 - 1.5e-05 24.7 0.2 2.4e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Ctf8 Mito_fiss_reg PF05308.6 KOS14716.1 - 0.93 8.8 7.9 0.065 12.5 0.9 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DNA_pol_B PF00136.16 KOS14717.1 - 5.4e-87 292.5 0.0 7.9e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KOS14717.1 - 2.5e-25 89.0 0.0 8.9e-12 44.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KOS14717.1 - 1.3e-09 37.9 6.1 2.8e-09 36.8 4.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 KOS14717.1 - 0.053 12.1 0.1 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral PolC_DP2 PF03833.8 KOS14717.1 - 1.7 6.1 1.2 2.6 5.5 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GalKase_gal_bdg PF10509.4 KOS14719.1 - 7.9e-21 73.0 0.0 1.7e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KOS14719.1 - 1.1e-11 44.7 0.1 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KOS14719.1 - 2.2e-09 37.2 0.5 4.3e-09 36.3 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain MA-Mit PF09245.5 KOS14719.1 - 0.053 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen LCM PF04072.9 KOS14720.1 - 1.7e-22 79.8 0.0 3e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TFIIA_gamma_C PF02751.9 KOS14722.1 - 7.3e-25 86.5 0.2 1e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KOS14722.1 - 2.3e-19 68.6 0.1 3.4e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_J PF04911.7 KOS14723.1 - 2.9e-21 74.6 0.3 3.1e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase j chain SPRY PF00622.23 KOS14724.1 - 5.1e-06 26.5 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 2 SPRY domain CRAL_TRIO PF00650.15 KOS14725.1 - 2.6e-37 127.7 0.0 3.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KOS14725.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS14725.1 - 0.014 15.5 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain EF-hand_1 PF00036.27 KOS14726.1 - 2.8e-24 82.5 10.9 2.2e-09 35.9 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KOS14726.1 - 3.1e-23 81.6 8.7 8.8e-14 51.3 1.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KOS14726.1 - 1.1e-20 71.6 10.4 3.9e-09 35.6 0.2 4.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 KOS14726.1 - 1.6e-17 62.8 11.8 1.1e-10 40.9 1.3 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KOS14726.1 - 1.1e-16 59.3 10.8 5.7e-06 25.4 0.1 3.8 3 1 1 4 4 4 3 EF hand EF-hand_9 PF14658.1 KOS14726.1 - 9.5e-10 38.2 0.3 8.4e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KOS14726.1 - 1.1e-08 34.7 1.2 5.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 KOS14726.1 - 0.0055 16.2 0.1 0.11 12.0 0.0 2.4 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.4 KOS14726.1 - 0.013 15.4 0.3 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3164 PF11363.3 KOS14726.1 - 0.018 14.4 0.2 4.3 6.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) DUF4373 PF14297.1 KOS14726.1 - 0.17 12.1 0.6 3.1 8.1 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4373) Complex1_LYR PF05347.10 KOS14727.1 - 2.2e-12 46.5 0.2 4e-12 45.7 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS14727.1 - 5.8e-11 42.4 0.3 8.5e-11 41.8 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KOS14727.1 - 0.00067 20.1 0.5 0.00085 19.7 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.20 KOS14728.1 - 6.8e-68 228.6 0.0 8.1e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14728.1 - 1.7e-49 168.2 0.0 2.2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14728.1 - 0.0048 15.8 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS14728.1 - 0.044 13.4 0.0 3.8 7.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family SE PF08491.5 KOS14729.1 - 7.5e-84 280.8 0.0 1e-82 277.0 0.0 2.4 2 1 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KOS14729.1 - 3.2e-13 49.3 0.5 5e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KOS14729.1 - 1.6e-08 34.0 1.9 2.7e-06 26.6 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KOS14729.1 - 4.2e-06 25.8 0.1 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A GDI PF00996.13 KOS14729.1 - 0.0013 17.1 0.1 0.0046 15.3 0.0 1.7 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 KOS14729.1 - 0.0029 16.5 1.5 1.7 7.5 0.1 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KOS14729.1 - 0.0047 16.8 0.0 0.0084 16.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS14729.1 - 0.0059 16.6 0.2 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KOS14729.1 - 0.02 13.7 1.0 0.2 10.4 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KOS14729.1 - 0.042 12.9 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KOS14729.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KOS14729.1 - 0.057 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KOS14729.1 - 0.074 13.0 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KOS14729.1 - 0.099 12.2 0.1 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KOS14729.1 - 0.15 12.5 1.3 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KOS14729.1 - 0.17 11.6 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family ATP-synt_10 PF05176.9 KOS14730.1 - 3.2e-63 213.3 0.0 4.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DnaJ PF00226.26 KOS14731.1 - 2.7e-22 78.2 0.8 2.7e-22 78.2 0.5 1.5 2 0 0 2 2 2 1 DnaJ domain Bacteriocin_IIc PF10439.4 KOS14731.1 - 0.026 14.6 4.0 0.037 14.1 2.8 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 KOS14731.1 - 0.032 13.9 0.2 0.069 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KOS14731.1 - 0.27 10.8 7.3 0.46 10.1 5.1 1.3 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KOS14731.1 - 0.34 10.4 7.3 1 8.9 5.1 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KOS14731.1 - 0.49 10.1 8.6 1.5 8.5 0.3 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain Mcp5_PH PF12814.2 KOS14732.1 - 2.2e-33 114.8 0.0 8.8e-33 112.8 0.0 2.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology UPRTase PF14681.1 KOS14734.1 - 2.4e-78 262.0 0.0 2.7e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KOS14734.1 - 0.00017 21.2 0.0 0.00025 20.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NGP1NT PF08153.7 KOS14735.1 - 1.4e-43 147.9 0.0 1.4e-43 147.9 0.0 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KOS14735.1 - 2.1e-19 69.5 0.0 1.6e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS14735.1 - 5.1e-06 25.8 0.1 2.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS14735.1 - 0.00024 20.3 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 KOS14735.1 - 0.00071 18.8 0.1 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS14735.1 - 0.0062 16.0 0.1 0.54 9.6 0.0 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS14735.1 - 0.062 13.1 9.1 1.3 8.8 0.0 4.3 4 2 1 5 5 5 0 Dynamin family Pox_RNA_Pol_19 PF05320.7 KOS14735.1 - 0.22 11.2 11.0 0.85 9.3 7.6 2.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 KOS14735.1 - 0.67 8.6 27.9 1 8.0 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.4 KOS14735.1 - 3.2 5.1 6.5 4.9 4.6 4.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UAA PF08449.6 KOS14736.1 - 2e-16 59.8 14.8 3.8e-16 58.8 10.3 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KOS14736.1 - 1.4e-10 41.0 6.9 1.4e-10 41.0 4.8 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KOS14736.1 - 0.002 18.1 8.8 0.002 18.1 6.1 2.9 2 1 1 3 3 3 1 EamA-like transporter family Ribosomal_L3 PF00297.17 KOS14737.1 - 1.5e-38 132.7 0.5 7.8e-38 130.3 0.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 PX PF00787.19 KOS14738.1 - 2.3e-20 72.4 1.4 5.3e-20 71.3 0.2 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KOS14738.1 - 3.1e-06 26.6 2.0 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like DUF3250 PF11618.3 KOS14738.1 - 0.024 14.8 0.2 5.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3250) LSM PF01423.17 KOS14739.1 - 2.4e-12 46.2 0.0 3.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain zf-C3HC4_2 PF13923.1 KOS14740.1 - 2.1e-06 27.6 23.9 0.00083 19.3 1.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KOS14740.1 - 1.9e-05 24.0 10.2 5.3e-05 22.5 1.9 3.1 2 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4 PF00097.20 KOS14740.1 - 5.7e-05 22.6 23.0 0.022 14.3 8.5 3.1 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS14740.1 - 0.00011 21.8 26.1 0.00057 19.5 9.3 3.4 2 2 1 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.1 KOS14740.1 - 0.00034 20.3 23.0 0.065 13.0 8.8 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.1 KOS14740.1 - 0.0027 17.5 20.8 0.039 13.8 1.5 3.3 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KOS14740.1 - 0.0064 16.1 16.4 0.019 14.6 6.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Atg14 PF10186.4 KOS14740.1 - 0.031 13.2 6.3 0.062 12.2 4.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TATR PF03430.8 KOS14740.1 - 0.19 10.3 2.6 0.25 9.9 1.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DYW_deaminase PF14432.1 KOS14740.1 - 0.67 9.9 6.6 0.21 11.5 1.6 2.4 2 1 0 2 2 2 0 DYW family of nucleic acid deaminases FYVE PF01363.16 KOS14740.1 - 1.4 8.8 20.5 0.17 11.7 7.3 2.7 2 1 0 2 2 2 0 FYVE zinc finger NUDIX PF00293.23 KOS14741.1 - 7.1e-16 58.0 0.5 1.1e-15 57.4 0.4 1.3 1 1 0 1 1 1 1 NUDIX domain Clathrin PF00637.15 KOS14742.1 - 9.5e-203 663.9 30.8 8.1e-33 113.0 0.2 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KOS14742.1 - 5e-31 106.3 1.4 2.1e-30 104.4 0.0 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.15 KOS14742.1 - 2.4e-28 96.4 0.4 0.0004 20.4 0.0 7.3 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin-link PF09268.5 KOS14742.1 - 5.2e-10 38.1 1.3 8.5e-10 37.4 0.1 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 KOS14742.1 - 1.3e-08 34.1 3.1 0.01 14.6 0.0 4.8 5 0 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.23 KOS14742.1 - 1.1e-05 24.7 4.3 0.53 9.9 0.3 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14742.1 - 0.00033 20.3 6.2 0.49 10.4 0.3 6.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS14742.1 - 0.026 14.4 13.0 2.7 7.9 0.5 7.0 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14742.1 - 0.082 12.7 11.3 3.9 7.5 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14742.1 - 0.17 12.5 18.0 17 6.4 0.1 9.2 11 1 1 12 12 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 KOS14742.1 - 0.51 10.0 14.0 0.67 9.6 0.2 6.3 7 1 0 7 7 7 0 TPR repeat ETC_C1_NDUFA5 PF04716.9 KOS14743.1 - 5.8e-15 54.5 0.0 8.5e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF4604 PF15377.1 KOS14744.1 - 4.3e-13 49.7 0.2 6e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2702 PF10863.3 KOS14744.1 - 0.058 13.1 0.2 0.08 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) ACPS PF01648.15 KOS14745.1 - 3.9e-11 42.7 0.0 2.2e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily Phospho_p8 PF10195.4 KOS14746.1 - 0.069 13.0 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Rep_fac-A_3 PF08661.6 KOS14747.1 - 2.2e-20 72.6 0.0 2.5e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4431 PF14485.1 KOS14747.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) RabGAP-TBC PF00566.13 KOS14748.1 - 2.4e-28 99.0 3.8 4.6e-26 91.6 1.5 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain G-gamma PF00631.17 KOS14748.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 GGL domain DUF155 PF02582.9 KOS14749.1 - 8.7e-42 142.9 0.0 1.4e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MCM PF00493.18 KOS14750.1 - 1.3e-128 428.4 0.0 1.2e-125 418.6 0.0 2.2 2 0 0 2 2 2 2 MCM2/3/5 family Ras PF00071.17 KOS14750.1 - 7e-61 204.3 0.2 1.5e-60 203.2 0.1 1.6 2 0 0 2 2 1 1 Ras family MCM_N PF14551.1 KOS14750.1 - 9.8e-21 74.4 0.0 3.6e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Miro PF08477.8 KOS14750.1 - 5.5e-20 72.0 0.0 1.5e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS14750.1 - 1.4e-11 43.9 0.0 2.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Mg_chelatase PF01078.16 KOS14750.1 - 4.6e-09 35.7 0.0 1.4e-06 27.6 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 KOS14750.1 - 1.2e-05 25.2 0.1 5.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sigma54_activat PF00158.21 KOS14750.1 - 2.9e-05 23.6 0.0 0.024 14.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 KOS14750.1 - 9.8e-05 22.0 0.1 0.38 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS14750.1 - 0.00021 21.4 0.2 0.0042 17.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KOS14750.1 - 0.0003 20.2 0.1 0.0057 16.1 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KOS14750.1 - 0.00083 18.5 0.0 0.018 14.2 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Sporozoite_P67 PF05642.6 KOS14750.1 - 0.00092 17.2 2.0 0.0015 16.5 1.4 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AAA_3 PF07726.6 KOS14750.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KOS14750.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 KOS14750.1 - 0.11 12.4 4.0 0.69 9.8 0.1 3.5 4 1 0 4 4 4 0 AAA ATPase domain SRPRB PF09439.5 KOS14750.1 - 0.12 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PBP1_TM PF14812.1 KOS14750.1 - 1.4 9.2 8.0 3.2 8.1 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ADH_zinc_N PF00107.21 KOS14751.1 - 0.0057 16.1 0.1 0.013 15.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS14751.1 - 0.017 14.8 0.0 2.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KOS14752.1 - 5.7e-08 33.1 0.0 1.7e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS14752.1 - 0.00037 20.1 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14752.1 - 0.0022 18.3 0.0 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS14752.1 - 0.0048 17.4 0.0 0.025 15.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS14752.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14752.1 - 0.0084 16.5 0.0 0.027 14.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KOS14752.1 - 0.011 15.1 0.0 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RCC1 PF00415.13 KOS14754.1 - 7.3e-29 99.7 11.5 1.3e-09 38.0 0.1 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KOS14754.1 - 4.9e-12 45.1 16.9 1.9e-06 27.3 0.0 6.1 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Racemase_4 PF13615.1 KOS14755.1 - 2.8e-20 72.4 0.2 6.8e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 KOS14755.1 - 1.6e-13 50.3 0.0 3.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Nitr_red_bet_C PF14711.1 KOS14755.1 - 0.1 12.1 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal DUF2418 PF10332.4 KOS14757.1 - 2e-24 85.7 0.5 3.6e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) MOZ_SAS PF01853.13 KOS14758.1 - 3.1e-77 258.0 0.6 4.6e-77 257.5 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KOS14758.1 - 3.6e-15 55.3 30.8 3.8e-11 42.5 3.3 3.4 2 1 1 3 3 3 2 PHD-finger Cript PF10235.4 KOS14759.1 - 4.1e-24 84.7 3.3 4.1e-24 84.7 2.3 1.4 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT Mu-like_Com PF10122.4 KOS14759.1 - 0.00059 18.8 1.2 0.51 9.4 0.1 2.5 2 0 0 2 2 2 2 Mu-like prophage protein Com Tnp_zf-ribbon_2 PF13842.1 KOS14759.1 - 0.04 14.3 11.3 0.04 14.3 7.8 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon C6_DPF PF10170.4 KOS14759.1 - 0.13 12.3 6.2 0.057 13.4 2.4 1.8 1 1 0 2 2 2 0 Cysteine-rich domain DZR PF12773.2 KOS14759.1 - 0.19 11.5 10.8 1 9.2 5.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KOS14759.1 - 0.21 11.1 8.0 4.1 7.0 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF2039 PF10217.4 KOS14759.1 - 0.24 11.4 12.6 0.055 13.4 4.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 KOS14759.1 - 0.29 10.9 6.9 0.1 12.4 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) C1_1 PF00130.17 KOS14759.1 - 0.91 9.2 11.8 13 5.6 3.6 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Gin PF10764.4 KOS14759.1 - 1.2 8.8 7.3 21 4.9 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Prok-RING_1 PF14446.1 KOS14759.1 - 1.4 8.6 13.6 3.3 7.5 3.1 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Sgf11 PF08209.6 KOS14759.1 - 8.1 5.8 7.5 18 4.7 0.0 3.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Sec39 PF08314.6 KOS14760.1 - 5.6e-27 94.0 0.0 8.2e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 CedA PF10729.4 KOS14760.1 - 0.0059 16.1 0.3 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 Cell division activator CedA Pkinase PF00069.20 KOS14761.1 - 1.2e-56 191.7 0.0 1.6e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14761.1 - 5.3e-29 101.0 0.0 7.7e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14761.1 - 0.044 12.7 0.0 1.6 7.6 0.0 2.4 3 0 0 3 3 3 0 Kinase-like COX7C PF02935.11 KOS14762.1 - 3.1e-06 26.8 0.1 3.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MT-A70 PF05063.9 KOS14763.1 - 2.1e-53 180.4 0.1 6.4e-53 178.8 0.1 1.7 1 1 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 KOS14763.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNB PF00773.14 KOS14764.1 - 5.7e-93 311.7 0.1 7.5e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KOS14764.1 - 2.2e-12 47.2 0.1 7.9e-12 45.4 0.1 2.0 1 0 0 1 1 1 1 PIN domain DUF1953 PF09196.5 KOS14764.1 - 0.069 12.8 0.0 0.43 10.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1953) OB_RNB PF08206.6 KOS14764.1 - 0.075 12.5 0.1 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain LSM PF01423.17 KOS14765.1 - 3.5e-16 58.5 0.8 6.6e-16 57.6 0.6 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS14765.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain NIR_SIR PF01077.17 KOS14766.1 - 1e-45 154.9 0.0 6.3e-39 132.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 KOS14766.1 - 2.6e-28 98.8 0.1 7.3e-28 97.3 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.12 KOS14766.1 - 1.1e-27 95.4 0.0 7.7e-13 47.8 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 KOS14766.1 - 1.9e-08 34.1 0.9 3.8e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg YwhD PF08741.5 KOS14766.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 YwhD family HtaA PF04213.8 KOS14766.1 - 0.14 12.3 0.2 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Htaa Spt20 PF12090.3 KOS14767.1 - 7e-37 126.5 0.0 2.9e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 Spt20 family MCLC PF05934.6 KOS14767.1 - 1.6 6.9 3.9 2.2 6.4 2.7 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Dicty_REP PF05086.7 KOS14767.1 - 2.5 5.7 3.5 3.3 5.3 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 KOS14767.1 - 4 6.5 15.8 7.2 5.7 10.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PEX11 PF05648.9 KOS14768.1 - 1.8e-17 63.3 0.1 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) STAS_2 PF13466.1 KOS14768.1 - 0.013 15.5 0.8 0.029 14.3 0.6 1.6 1 0 0 1 1 1 0 STAS domain Ribosomal_S17 PF00366.15 KOS14769.1 - 3.4e-15 55.8 0.3 5.3e-15 55.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 MgsA_C PF12002.3 KOS14770.1 - 7.1e-53 178.7 0.1 1.8e-52 177.4 0.0 1.7 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KOS14770.1 - 4.7e-16 59.1 0.0 8.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS14770.1 - 4.8e-15 55.2 0.0 7.7e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS14770.1 - 9.1e-10 38.7 1.5 3.8e-07 30.2 0.6 3.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KOS14770.1 - 1.1e-08 34.9 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS14770.1 - 3.9e-08 33.4 3.6 4.8e-05 23.4 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KOS14770.1 - 2.9e-07 30.4 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KOS14770.1 - 6.8e-06 25.3 0.2 0.076 12.1 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KOS14770.1 - 4.4e-05 23.4 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KOS14770.1 - 5e-05 22.8 0.0 8.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KOS14770.1 - 5.2e-05 22.7 0.0 0.0027 17.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 KOS14770.1 - 0.00022 22.0 0.0 0.0012 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS14770.1 - 0.00042 20.0 0.1 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KOS14770.1 - 0.00068 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 KOS14770.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KOS14770.1 - 0.0016 18.0 0.8 0.0051 16.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KOS14770.1 - 0.003 17.2 0.0 0.87 9.2 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 KOS14770.1 - 0.0033 17.2 0.7 0.012 15.4 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS14770.1 - 0.0037 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KOS14770.1 - 0.0066 15.3 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Sgf11 PF08209.6 KOS14770.1 - 0.0069 15.6 0.6 0.015 14.5 0.4 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) AAA_18 PF13238.1 KOS14770.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KOS14770.1 - 0.012 14.3 0.0 0.034 12.8 0.0 1.5 1 1 0 2 2 2 0 TIP49 C-terminus AAA_10 PF12846.2 KOS14770.1 - 0.016 14.6 0.1 0.33 10.3 0.1 2.3 1 1 0 1 1 1 0 AAA-like domain DNA_pol3_delta2 PF13177.1 KOS14770.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AFG1_ATPase PF03969.11 KOS14770.1 - 0.03 13.1 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase NTPase_1 PF03266.10 KOS14770.1 - 0.035 13.8 0.3 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 NTPase NACHT PF05729.7 KOS14770.1 - 0.041 13.5 0.1 0.15 11.6 0.1 2.0 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KOS14770.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 KOS14770.1 - 0.052 13.1 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KOS14770.1 - 0.058 13.0 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KOS14770.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MCM PF00493.18 KOS14770.1 - 0.073 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Viral_helicase1 PF01443.13 KOS14770.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KOS14770.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KOS14770.1 - 0.13 11.1 0.0 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KOS14770.1 - 0.3 10.4 3.1 0.39 10.0 0.2 2.4 2 1 1 3 3 3 0 AAA domain zf-RING_3 PF14369.1 KOS14770.1 - 0.59 10.1 3.4 12 6.0 0.3 3.3 3 0 0 3 3 3 0 zinc-finger Bot1p PF12298.3 KOS14771.1 - 3.6e-24 85.6 0.1 5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 KOS14771.1 - 0.0055 16.6 0.1 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 SCP2 PF02036.12 KOS14772.1 - 5.3e-23 81.2 1.8 6.3e-23 81.0 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KOS14772.1 - 0.00075 19.4 0.8 0.0009 19.2 0.6 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Myb_DNA-binding PF00249.26 KOS14773.1 - 0.0063 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS14773.1 - 0.029 14.4 2.5 0.035 14.2 0.6 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain HCMV_UL139 PF12507.3 KOS14773.1 - 0.037 14.1 2.7 0.075 13.1 1.8 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Clathrin PF00637.15 KOS14774.1 - 1.7e-18 66.6 1.1 1.9e-13 50.2 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KOS14774.1 - 0.00065 19.4 7.4 0.0018 18.0 5.1 1.8 1 0 0 1 1 1 1 Ring finger domain VPS11_C PF12451.3 KOS14774.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 KOS14774.1 - 0.0013 18.4 5.0 0.0025 17.5 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KOS14774.1 - 0.0051 16.8 1.2 0.016 15.3 0.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KOS14774.1 - 0.017 15.1 6.8 0.036 14.1 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS14774.1 - 0.06 13.0 4.8 0.12 12.0 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS14774.1 - 0.24 11.2 1.5 0.73 9.7 1.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cyclin PF08613.6 KOS14776.1 - 2.7e-14 53.8 0.0 3.1e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KOS14776.1 - 0.0029 17.1 0.1 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain PHD_2 PF13831.1 KOS14776.1 - 0.026 13.8 0.1 0.058 12.7 0.1 1.6 1 0 0 1 1 1 0 PHD-finger DUF2404 PF10296.4 KOS14777.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) EF_TS PF00889.14 KOS14778.1 - 3.4e-18 65.7 0.0 9e-18 64.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS NYAP_C PF15452.1 KOS14778.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter ABC_membrane_2 PF06472.10 KOS14779.1 - 4.7e-94 314.6 4.6 7.2e-94 314.0 3.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KOS14779.1 - 6.8e-17 62.0 0.0 6.8e-16 58.8 0.0 2.6 3 0 0 3 3 2 1 ABC transporter RuvB_N PF05496.7 KOS14779.1 - 0.0024 16.9 0.1 0.0063 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KOS14779.1 - 0.0048 17.6 0.1 0.016 16.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KOS14779.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KOS14779.1 - 0.023 14.6 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 KOS14779.1 - 0.024 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS14779.1 - 0.028 14.1 0.3 0.27 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KOS14779.1 - 0.033 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KOS14779.1 - 0.036 14.2 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS14779.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KOS14779.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 KOS14779.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KOS14779.1 - 0.44 10.8 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain tRNA-synt_1d PF00750.14 KOS14780.1 - 9.7e-85 284.4 0.1 1.3e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KOS14780.1 - 2.2e-21 76.0 0.7 6.3e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain PDDEXK_1 PF12705.2 KOS14780.1 - 0.8 9.0 4.1 0.9 8.8 1.9 1.7 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Cpn60_TCP1 PF00118.19 KOS14781.1 - 7.1e-140 466.8 3.2 8.3e-140 466.6 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.24 KOS14782.1 - 4.1e-43 146.7 0.0 7.2e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS14782.1 - 8.8e-08 32.3 0.1 5.1e-06 26.6 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KOS14782.1 - 1e-07 31.7 0.1 4.9e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS14782.1 - 8.2e-07 29.2 0.1 0.00033 20.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KOS14782.1 - 3.5e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KOS14782.1 - 3.5e-05 22.9 0.0 6.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KOS14782.1 - 4.4e-05 23.1 0.2 0.00015 21.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF4200 PF13863.1 KOS14782.1 - 0.00079 19.3 1.7 0.00079 19.3 1.2 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) TIP49 PF06068.8 KOS14782.1 - 0.00086 18.1 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 KOS14782.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KOS14782.1 - 0.0013 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KOS14782.1 - 0.0016 19.2 1.4 0.0029 18.4 0.1 2.3 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KOS14782.1 - 0.0017 17.5 0.0 0.0043 16.1 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.1 KOS14782.1 - 0.0017 17.9 0.2 0.022 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KOS14782.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KOS14782.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KOS14782.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS14782.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KOS14782.1 - 0.0062 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KOS14782.1 - 0.007 16.6 0.4 0.028 14.7 0.0 2.2 2 1 0 3 3 1 1 AAA domain PhoH PF02562.11 KOS14782.1 - 0.0095 15.1 0.2 0.021 14.0 0.1 1.5 1 1 0 1 1 1 1 PhoH-like protein AAA_24 PF13479.1 KOS14782.1 - 0.0097 15.5 0.2 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KOS14782.1 - 0.011 15.2 0.1 0.034 13.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 KOS14782.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KOS14782.1 - 0.014 15.0 0.0 0.22 11.1 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Tropomyosin_1 PF12718.2 KOS14782.1 - 0.015 15.1 5.3 0.017 14.9 1.7 2.0 2 0 0 2 2 2 0 Tropomyosin like ResIII PF04851.10 KOS14782.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KOS14782.1 - 0.019 14.0 0.6 0.061 12.4 0.0 2.1 2 1 1 3 3 3 0 KaiC AAA_25 PF13481.1 KOS14782.1 - 0.027 13.8 0.2 0.098 12.0 0.1 1.8 1 1 1 2 2 2 0 AAA domain DUF4140 PF13600.1 KOS14782.1 - 0.037 14.4 2.7 0.14 12.5 1.4 2.3 3 0 0 3 3 1 0 N-terminal domain of unknown function (DUF4140) NACHT PF05729.7 KOS14782.1 - 0.044 13.4 0.0 0.15 11.7 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KOS14782.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KOS14782.1 - 0.074 13.3 0.8 7.1 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KOS14782.1 - 0.074 11.8 0.0 0.41 9.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KOS14782.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 KOS14782.1 - 0.12 11.9 0.5 0.47 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KOS14782.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IncA PF04156.9 KOS14782.1 - 0.17 11.4 0.7 0.43 10.1 0.5 1.6 1 0 0 1 1 1 0 IncA protein FBPase PF00316.15 KOS14783.1 - 4.9e-129 429.8 0.0 5.7e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KOS14783.1 - 0.021 14.1 0.0 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 Inositol monophosphatase family PLDc PF00614.17 KOS14784.1 - 9.7e-14 50.6 0.2 8.4e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KOS14784.1 - 1.8e-12 47.1 0.0 4.4e-07 29.6 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 KOS14784.1 - 0.00022 20.9 1.3 0.00055 19.7 0.6 1.9 2 0 0 2 2 2 1 PX domain Cyclin_N PF00134.18 KOS14785.1 - 6.8e-15 54.7 0.7 1.3e-14 53.8 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KOS14785.1 - 9.7e-13 48.7 1.5 1.1e-12 48.6 0.2 1.7 2 0 0 2 2 2 1 Cyclin Xpo1 PF08389.7 KOS14786.1 - 1.8e-24 86.3 0.0 8.4e-24 84.1 0.0 2.3 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 KOS14786.1 - 1.4e-06 28.1 0.3 4.9e-06 26.3 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pkinase PF00069.20 KOS14787.1 - 4.8e-66 222.5 0.0 6.4e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14787.1 - 3e-45 154.3 0.0 4.3e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14787.1 - 6.8e-11 41.6 0.0 3.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KOS14787.1 - 0.0066 16.2 1.3 0.11 12.2 0.0 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS14787.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KOS14787.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CBFD_NFYB_HMF PF00808.18 KOS14788.1 - 2.6e-18 65.8 0.1 4.7e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Toxin_63 PF15541.1 KOS14788.1 - 0.037 13.9 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 63 Myosin_head PF00063.16 KOS14789.1 - 1.5e-245 816.5 0.0 1.5e-245 816.5 0.0 2.5 2 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 KOS14789.1 - 0.00026 20.5 0.1 0.0005 19.6 0.1 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KOS14789.1 - 0.0094 15.6 0.1 0.12 12.0 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 KOS14789.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.7 3 1 1 4 4 4 0 AAA domain DUF3040 PF11239.3 KOS14789.1 - 0.7 9.9 5.1 0.56 10.2 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Reo_sigmaC PF04582.7 KOS14789.1 - 3.6 6.6 30.3 4.5 6.3 5.2 3.7 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 KOS14789.1 - 8.7 5.7 85.4 0.044 13.2 34.8 3.3 1 1 3 4 4 4 0 Intermediate filament protein COX14 PF14880.1 KOS14790.1 - 2e-05 24.0 1.8 2e-05 24.0 1.3 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PNP_UDP_1 PF01048.15 KOS14791.1 - 5.8e-35 120.3 0.1 6.8e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Aldo_ket_red PF00248.16 KOS14792.1 - 4.5e-55 186.4 0.0 5.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Molydop_binding PF01568.16 KOS14792.1 - 0.096 12.5 0.1 0.85 9.4 0.1 2.2 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain EMP24_GP25L PF01105.19 KOS14793.1 - 5e-34 117.6 0.1 5.7e-34 117.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Mycobact_memb PF05423.8 KOS14793.1 - 0.21 11.3 1.5 1.5 8.5 0.3 2.2 2 0 0 2 2 2 0 Mycobacterium membrane protein SMC_N PF02463.14 KOS14794.1 - 2.9e-75 252.3 0.0 4.1e-75 251.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS14794.1 - 1.4e-26 92.7 0.0 4.2e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS14794.1 - 1.7e-15 57.8 0.1 9.1e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KOS14794.1 - 3e-06 26.5 0.1 0.0011 18.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KOS14794.1 - 4e-06 27.3 21.8 4e-06 27.3 15.1 5.4 3 2 0 3 3 2 1 AAA domain Tropomyosin PF00261.15 KOS14794.1 - 5.5e-05 22.3 1.8 5.5e-05 22.3 1.2 7.0 3 2 3 7 7 7 2 Tropomyosin AAA_29 PF13555.1 KOS14794.1 - 6.2e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliJ PF02050.11 KOS14794.1 - 0.0067 16.4 14.4 0.0067 16.4 10.0 9.8 3 3 7 11 11 9 2 Flagellar FliJ protein DUF4415 PF14384.1 KOS14794.1 - 0.007 16.5 2.7 4.2 7.5 0.0 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4415) ABC_tran PF00005.22 KOS14794.1 - 0.19 12.0 0.0 0.19 12.0 0.0 5.9 4 2 0 4 4 3 0 ABC transporter Reo_sigmaC PF04582.7 KOS14794.1 - 8.9 5.3 34.2 3.4 6.7 2.8 4.7 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Kinesin PF00225.18 KOS14795.1 - 9.9e-103 343.3 0.2 1.2e-102 343.0 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain CENP-F_leu_zip PF10473.4 KOS14795.1 - 0.029 14.2 13.3 0.08 12.7 3.2 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 O-FucT PF10250.4 KOS14795.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Sterol_MT_C PF08498.5 KOS14796.1 - 4.2e-28 97.0 0.2 6.4e-28 96.5 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 KOS14796.1 - 3.3e-19 68.9 0.0 4.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS14796.1 - 1.5e-17 63.8 0.0 3.2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS14796.1 - 1.4e-16 60.6 0.0 2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS14796.1 - 7.3e-15 54.7 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KOS14796.1 - 6.4e-14 52.4 0.0 4.6e-13 49.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS14796.1 - 1.2e-12 47.9 0.0 3.2e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS14796.1 - 1.3e-11 44.8 0.2 5.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS14796.1 - 1.5e-11 44.5 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KOS14796.1 - 8.6e-07 28.3 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KOS14796.1 - 4.3e-06 26.3 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KOS14796.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KOS14796.1 - 2.9e-05 23.5 0.0 7.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_3 PF01596.12 KOS14796.1 - 0.00019 20.5 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 KOS14796.1 - 0.00076 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 KOS14796.1 - 0.0032 16.6 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KOS14796.1 - 0.0037 16.6 0.0 0.0086 15.4 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KOS14796.1 - 0.0065 17.2 0.0 0.021 15.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KOS14796.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_32 PF13679.1 KOS14796.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DHO_dh PF01180.16 KOS14797.1 - 1.1e-95 320.0 0.0 1.9e-95 319.2 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KOS14797.1 - 7.2e-06 25.0 0.0 0.00022 20.1 0.0 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase BtpA PF03437.10 KOS14797.1 - 0.059 12.6 0.1 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 BtpA family FTHFS PF01268.14 KOS14798.1 - 5.6e-261 866.3 0.0 1.7e-260 864.8 0.0 1.7 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KOS14798.1 - 3.4e-61 205.0 1.4 3.4e-61 205.0 1.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KOS14798.1 - 5.2e-37 126.4 0.2 1.2e-36 125.2 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain MAP65_ASE1 PF03999.7 KOS14799.1 - 8.1e-52 176.6 2.5 1.7e-50 172.3 1.7 2.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) HCaRG PF07258.9 KOS14799.1 - 0.024 14.1 0.5 0.06 12.8 0.3 1.6 1 0 0 1 1 1 0 HCaRG protein FlaC_arch PF05377.6 KOS14799.1 - 0.071 13.0 0.1 0.27 11.1 0.0 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prok-TraM PF09228.5 KOS14799.1 - 0.12 12.5 1.8 0.42 10.8 0.0 2.8 4 0 0 4 4 4 0 Prokaryotic Transcriptional repressor TraM DUF342 PF03961.8 KOS14799.1 - 0.18 10.1 0.1 2.1 6.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) UQ_con PF00179.21 KOS14800.1 - 5.5e-47 158.7 0.0 6.6e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS14800.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KOS14800.1 - 0.0074 15.9 0.1 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KOS14800.1 - 0.026 14.3 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.21 KOS14801.1 - 6.7e-39 132.5 0.1 7.8e-39 132.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEMT PF04191.8 KOS14802.1 - 1.5e-54 182.6 10.5 2e-31 108.2 0.9 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF4199 PF13858.1 KOS14802.1 - 4.1e-05 23.5 0.0 0.28 11.0 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF4199) Herpes_capsid PF06112.6 KOS14802.1 - 1.1 9.2 14.5 0.56 10.2 8.2 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF2871 PF11070.3 KOS14802.1 - 6.3 6.9 8.8 7.8 6.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2871) Ribosomal_L36 PF00444.13 KOS14803.1 - 1.4e-20 72.9 9.6 2e-20 72.4 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Pkinase PF00069.20 KOS14804.1 - 9.1e-41 139.7 0.0 1.1e-39 136.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14804.1 - 4e-21 75.2 0.0 1.8e-12 46.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KOS14804.1 - 5.3e-07 28.8 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KOS14804.1 - 0.01 15.5 1.4 0.14 11.8 0.3 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family GTP_EFTU PF00009.22 KOS14805.1 - 5e-56 189.1 0.1 7.4e-56 188.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KOS14805.1 - 2e-36 124.1 0.0 4.6e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KOS14805.1 - 3.9e-17 62.1 0.6 1.1e-16 60.7 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KOS14805.1 - 0.00016 21.2 0.1 0.00016 21.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KOS14805.1 - 0.0018 18.1 0.3 0.0062 16.4 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase 5HT_transporter PF03491.8 KOS14805.1 - 0.023 14.8 0.2 0.083 13.0 0.0 2.0 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Cation_efflux PF01545.16 KOS14806.1 - 6.9e-77 258.3 2.7 9.4e-77 257.8 1.9 1.1 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 KOS14806.1 - 0.00013 21.4 0.7 0.00035 19.9 0.5 1.7 1 0 0 1 1 1 1 High-affinity nickel-transport protein Zip PF02535.17 KOS14806.1 - 0.051 12.5 11.9 0.1 11.5 8.2 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Herpes_LMP1 PF05297.6 KOS14806.1 - 2.6 6.8 9.1 0.34 9.7 0.6 2.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) His_Phos_2 PF00328.17 KOS14807.1 - 7.6e-69 232.6 0.0 1.2e-68 232.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KOS14807.1 - 5.9e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Frag1 PF10277.4 KOS14808.1 - 1.6e-18 67.0 0.2 1.6e-18 67.0 0.2 3.5 3 1 1 5 5 5 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KOS14808.1 - 0.00038 20.4 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF543 PF04418.7 KOS14809.1 - 1e-25 89.4 0.7 1.9e-25 88.6 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF543) ApoC-I PF04691.7 KOS14809.1 - 0.0033 17.0 1.0 0.014 15.0 0.2 2.0 1 1 1 2 2 2 1 Apolipoprotein C-I (ApoC-1) CagY_I PF14585.1 KOS14809.1 - 0.027 14.3 2.6 0.33 10.9 2.5 1.9 1 1 1 2 2 2 0 CagY type 1 repeat DUF883 PF05957.8 KOS14809.1 - 0.062 13.6 3.9 0.85 10.0 0.5 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2317 PF10079.4 KOS14809.1 - 0.075 11.6 0.3 0.088 11.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) YtxH PF12732.2 KOS14809.1 - 3.1 8.2 8.6 0.46 10.8 1.4 2.5 2 1 0 2 2 2 0 YtxH-like protein Ribosomal_S7 PF00177.16 KOS14810.1 - 2.5e-33 114.7 0.1 3.3e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF619 PF04768.8 KOS14811.1 - 1.9e-40 138.0 0.0 3.3e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KOS14811.1 - 1e-24 87.1 0.0 2.7e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KOS14811.1 - 3.7e-23 82.3 0.0 5.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 KOS14811.1 - 2.3e-07 30.8 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 KOS14811.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arm PF00514.18 KOS14811.1 - 0.018 14.8 0.3 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pam16 PF03656.8 KOS14811.1 - 0.055 13.2 0.8 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Pam16 adh_short PF00106.20 KOS14812.1 - 6.5e-22 78.2 0.1 1e-21 77.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KOS14812.1 - 2.1e-16 60.4 0.0 4.3e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KOS14812.1 - 1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KOS14812.1 - 0.0015 17.6 0.1 0.0047 16.0 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.10 KOS14812.1 - 0.036 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KOS14812.1 - 0.036 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.17 KOS14813.1 - 1.3e-66 222.9 0.3 1.5e-66 222.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS14813.1 - 7.4e-19 68.3 0.0 1.2e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS14813.1 - 4.5e-15 55.3 0.2 6.9e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS14813.1 - 7.6e-08 31.7 0.1 9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS14813.1 - 3.3e-06 26.6 0.3 8.3e-06 25.3 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS14813.1 - 5.4e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KOS14813.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KOS14813.1 - 0.0042 16.3 0.0 0.032 13.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KOS14813.1 - 0.011 14.8 0.2 0.07 12.3 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KOS14813.1 - 0.015 15.3 0.1 0.083 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KOS14813.1 - 0.019 15.1 0.0 0.078 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KOS14813.1 - 0.039 14.1 0.0 0.34 11.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KOS14813.1 - 0.042 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 KOS14813.1 - 0.046 13.2 1.5 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KOS14813.1 - 0.051 13.8 0.1 0.15 12.3 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KOS14813.1 - 0.11 12.2 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YTH PF04146.10 KOS14813.1 - 0.15 11.6 0.4 2.7 7.5 0.0 2.0 1 1 1 2 2 2 0 YT521-B-like domain TFIIB PF00382.14 KOS14814.1 - 1.4e-29 101.6 5.2 4.5e-18 64.8 0.6 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KOS14814.1 - 2.2e-14 52.5 0.6 3.6e-14 51.8 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KOS14814.1 - 0.0035 17.2 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain RB_B PF01857.15 KOS14814.1 - 0.0082 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain A2L_zn_ribbon PF08792.5 KOS14814.1 - 0.11 11.9 0.5 12 5.5 0.1 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 KOS14814.1 - 0.16 11.1 0.5 0.41 9.9 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KOS14814.1 - 0.26 10.9 2.5 6.3 6.5 0.0 3.4 3 0 0 3 3 3 0 Nudix N-terminal PIP5K PF01504.13 KOS14815.1 - 1e-78 263.9 0.0 1.6e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FCH PF00611.18 KOS14816.1 - 9.7e-21 73.7 0.4 9.7e-21 73.7 0.2 2.7 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KOS14816.1 - 3.7e-11 42.2 0.0 6.6e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS14816.1 - 9e-09 34.7 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS14816.1 - 3.5e-08 32.7 0.0 8e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SF-assemblin PF06705.6 KOS14816.1 - 0.23 10.5 7.8 2.7 7.0 2.6 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin DegT_DnrJ_EryC1 PF01041.12 KOS14816.1 - 1 8.2 4.2 0.86 8.5 1.1 1.9 1 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SUI1 PF01253.17 KOS14817.1 - 1.5e-14 53.5 0.0 2.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cgr1 PF03879.9 KOS14817.1 - 0.0052 16.9 8.7 0.0076 16.4 6.0 1.2 1 0 0 1 1 1 1 Cgr1 family Guanylate_kin PF00625.16 KOS14817.1 - 0.041 13.3 0.8 0.075 12.4 0.3 1.7 2 0 0 2 2 2 0 Guanylate kinase Mito_carr PF00153.22 KOS14818.1 - 2.8e-41 139.1 1.0 6.7e-16 57.7 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M24 PF00557.19 KOS14819.1 - 2e-41 141.8 0.0 3e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KOS14819.1 - 7.5e-27 94.4 0.0 1.3e-21 77.4 0.0 2.8 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain UQ_con PF00179.21 KOS14820.1 - 7.9e-23 80.4 0.0 8.3e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PMSR PF01625.16 KOS14821.1 - 3.3e-53 179.7 0.2 4e-53 179.4 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.10 KOS14821.1 - 0.015 14.8 0.2 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Iso_dh PF00180.15 KOS14822.1 - 4.9e-79 265.8 0.0 6.2e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RRM_1 PF00076.17 KOS14823.1 - 2.3e-18 65.5 0.1 3.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14823.1 - 8e-15 54.5 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14823.1 - 4.2e-13 48.9 0.0 6.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS14823.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Cyclin_N PF00134.18 KOS14824.1 - 2e-08 33.8 0.0 4.5e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain RecO_C PF02565.10 KOS14824.1 - 0.017 14.9 0.1 0.68 9.8 0.0 2.4 2 1 0 2 2 2 0 Recombination protein O C terminal Lum_binding PF00677.12 KOS14825.1 - 4.8e-31 106.5 0.0 3.4e-18 65.3 0.0 3.7 2 1 0 2 2 2 2 Lumazine binding domain JAB PF01398.16 KOS14826.1 - 1.1e-35 121.7 0.0 2.2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KOS14826.1 - 5.3e-27 94.1 1.3 5.3e-27 94.1 0.9 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KOS14826.1 - 2.2e-09 36.8 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MbeB_N PF04837.7 KOS14826.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Peptidase_S10 PF00450.17 KOS14827.1 - 8e-105 351.3 0.0 1.1e-104 350.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KOS14827.1 - 0.013 15.3 1.7 0.32 10.8 0.1 3.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Amidohydro_2 PF04909.9 KOS14828.1 - 2e-11 44.0 0.3 6.7e-11 42.2 0.1 1.7 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KOS14828.1 - 7e-05 22.9 0.7 0.00016 21.8 0.5 1.5 1 1 0 1 1 1 1 Amidohydrolase Histone PF00125.19 KOS14829.1 - 1.4e-22 79.6 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS14829.1 - 1.3e-06 28.3 0.1 2.9e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KOS14829.1 - 0.00031 20.9 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KOS14829.1 - 0.0095 16.4 0.2 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1018) RP-C PF03428.8 KOS14829.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain Mitofilin PF09731.4 KOS14829.1 - 0.023 13.3 1.1 0.028 13.0 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3530 PF12048.3 KOS14829.1 - 0.044 12.7 1.1 0.052 12.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Bt_P21 PF05560.6 KOS14829.1 - 0.063 12.6 0.1 0.075 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein LETM1 PF07766.8 KOS14830.1 - 2.2e-16 59.7 5.1 3.6e-09 36.0 0.6 2.1 2 0 0 2 2 2 2 LETM1-like protein UQ_con PF00179.21 KOS14831.1 - 1.5e-38 131.4 0.0 1.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KOS14831.1 - 0.093 12.6 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KOS14831.1 - 0.13 11.9 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Rhomboid PF01694.17 KOS14832.1 - 1.5e-25 89.9 13.6 1.5e-25 89.9 9.4 2.0 2 1 0 2 2 2 1 Rhomboid family DUF457 PF04307.9 KOS14832.1 - 0.053 12.8 1.3 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF202 PF02656.10 KOS14832.1 - 0.17 12.0 2.3 3.1 8.0 0.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) AAA_5 PF07728.9 KOS14833.1 - 1.4e-116 384.4 0.2 1.7e-20 73.1 0.0 9.9 9 1 1 10 10 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS14833.1 - 9.4e-24 83.4 0.0 6.4e-08 32.2 0.0 7.6 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KOS14833.1 - 2.1e-23 82.9 0.0 0.0036 17.5 0.0 7.0 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS14833.1 - 2.1e-22 79.6 3.3 0.016 15.3 0.0 8.7 7 1 0 7 7 7 6 AAA domain AAA_33 PF13671.1 KOS14833.1 - 1.5e-16 60.5 8.5 0.009 15.8 0.0 8.1 7 0 0 7 7 6 4 AAA domain AAA_16 PF13191.1 KOS14833.1 - 7.2e-16 58.7 55.6 0.00041 20.3 0.4 11.8 10 3 0 11 11 8 6 AAA ATPase domain ABC_tran PF00005.22 KOS14833.1 - 2.9e-15 56.7 0.3 0.0054 17.0 0.0 6.2 7 0 0 7 7 5 3 ABC transporter AAA_17 PF13207.1 KOS14833.1 - 3.5e-14 53.6 0.0 0.4 11.4 0.0 7.0 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.21 KOS14833.1 - 3.6e-14 52.6 0.1 0.08 12.4 0.0 6.9 6 0 0 6 6 6 3 Sigma-54 interaction domain T2SE PF00437.15 KOS14833.1 - 5.1e-14 51.8 0.0 0.074 11.9 0.0 6.8 6 1 0 6 6 6 3 Type II/IV secretion system protein AAA_29 PF13555.1 KOS14833.1 - 9.6e-14 50.6 2.3 0.15 11.6 0.0 6.1 6 0 0 6 6 6 4 P-loop containing region of AAA domain AAA_19 PF13245.1 KOS14833.1 - 3.4e-12 45.9 15.4 0.11 12.2 0.0 7.8 6 0 0 6 6 6 2 Part of AAA domain Sigma54_activ_2 PF14532.1 KOS14833.1 - 6e-12 45.7 1.9 0.0014 18.6 0.0 6.8 6 0 0 6 6 6 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KOS14833.1 - 1.3e-11 43.9 4.4 0.032 13.3 0.0 6.8 6 0 0 6 6 6 3 Zeta toxin AAA_14 PF13173.1 KOS14833.1 - 6.4e-11 42.2 0.0 0.0036 17.2 0.0 6.2 7 0 0 7 7 5 2 AAA domain NACHT PF05729.7 KOS14833.1 - 7.1e-11 42.0 1.3 0.13 11.9 0.1 6.5 6 0 0 6 6 6 1 NACHT domain AAA_28 PF13521.1 KOS14833.1 - 1.4e-10 41.3 3.3 0.55 10.1 0.0 7.5 6 0 0 6 6 6 1 AAA domain DUF258 PF03193.11 KOS14833.1 - 1.5e-10 40.4 0.1 0.044 12.9 0.0 5.2 5 0 0 5 5 5 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KOS14833.1 - 1.9e-10 41.1 0.1 1.2 9.4 0.0 6.6 6 0 0 6 6 6 1 AAA domain Mg_chelatase PF01078.16 KOS14833.1 - 2.7e-10 39.7 8.1 1.6 7.8 0.0 8.2 9 0 0 9 9 7 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 KOS14833.1 - 3.4e-10 40.4 0.0 1.9 8.9 0.0 6.5 6 0 0 6 6 6 1 Miro-like protein UPF0079 PF02367.12 KOS14833.1 - 9.7e-10 38.1 1.9 1.5 8.4 0.1 6.3 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KOS14833.1 - 2.3e-09 37.3 0.1 4.9 7.3 0.0 6.5 6 0 0 6 6 6 0 RNA helicase DUF815 PF05673.8 KOS14833.1 - 5.3e-09 35.3 1.5 0.55 9.1 0.0 4.9 5 0 0 5 5 5 3 Protein of unknown function (DUF815) MobB PF03205.9 KOS14833.1 - 6.2e-08 32.4 0.2 1.1 8.9 0.0 6.1 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KOS14833.1 - 4.2e-06 26.3 1.8 3.8 6.9 0.0 5.2 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain RuvB_N PF05496.7 KOS14833.1 - 1.2e-05 24.5 3.5 5.9 5.8 0.0 5.9 6 1 0 6 6 5 0 Holliday junction DNA helicase ruvB N-terminus vWA-TerF-like PF10138.4 KOS14833.1 - 4.4e-05 23.4 0.1 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus PhoH PF02562.11 KOS14833.1 - 5.7e-05 22.4 0.8 2.6 7.2 0.0 5.2 5 0 0 5 5 5 1 PhoH-like protein PduV-EutP PF10662.4 KOS14833.1 - 6.8e-05 22.3 1.9 1.2 8.6 0.1 4.6 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KOS14833.1 - 0.00079 18.9 6.2 3.3 7.1 0.1 6.2 7 0 0 7 7 7 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KOS14833.1 - 0.0031 17.0 3.6 7 6.1 0.0 5.0 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KOS14833.1 - 0.0081 16.1 0.0 71 3.3 0.0 4.9 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KOS14833.1 - 0.011 15.3 3.8 21 4.6 0.0 5.4 6 0 0 6 6 4 0 AAA domain Bac_DnaA PF00308.13 KOS14833.1 - 0.026 14.1 0.2 30 4.1 0.0 4.4 5 0 0 5 5 4 0 Bacterial dnaA protein AAA_6 PF12774.2 KOS14833.1 - 0.026 14.0 0.0 48 3.3 0.0 4.8 6 0 0 6 6 4 0 Hydrolytic ATP binding site of dynein motor region D1 Arch_ATPase PF01637.13 KOS14833.1 - 0.04 13.6 0.0 16 5.1 0.0 4.4 6 0 0 6 6 4 0 Archaeal ATPase SRPRB PF09439.5 KOS14833.1 - 0.045 12.9 1.5 51 3.0 0.0 4.8 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit PIF1 PF05970.9 KOS14833.1 - 0.055 12.4 0.3 9.5 5.0 0.0 3.9 4 0 0 4 4 4 0 PIF1-like helicase AAA_7 PF12775.2 KOS14833.1 - 0.11 11.5 0.6 35 3.3 0.0 4.0 3 0 0 3 3 3 0 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 KOS14833.1 - 0.14 11.6 0.0 14 5.1 0.0 3.9 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 KOS14833.1 - 0.14 12.0 0.0 15 5.4 0.0 2.8 4 0 0 4 4 2 0 AAA domain KAP_NTPase PF07693.9 KOS14833.1 - 0.19 10.6 0.0 51 2.6 0.0 3.7 3 0 0 3 3 3 0 KAP family P-loop domain ResIII PF04851.10 KOS14833.1 - 0.25 11.1 7.6 9.7 5.9 0.0 4.2 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KOS14833.1 - 0.26 11.5 24.3 0.36 11.1 0.0 6.1 6 1 0 6 6 5 0 AAA domain TIP49 PF06068.8 KOS14833.1 - 0.29 9.8 3.5 4.9 5.7 0.0 4.1 5 0 0 5 5 5 0 TIP49 C-terminus KaiC PF06745.8 KOS14833.1 - 0.31 10.1 0.8 25 3.9 0.0 3.7 4 0 0 4 4 4 0 KaiC DUF87 PF01935.12 KOS14833.1 - 1.2 8.8 1.0 39 3.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 PEPCK_ATP PF01293.15 KOS14833.1 - 1.8 7.0 0.0 3.9 5.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase NTPase_1 PF03266.10 KOS14833.1 - 2.1 8.0 4.5 64 3.2 0.3 4.4 6 0 0 6 6 4 0 NTPase Septin PF00735.13 KOS14833.1 - 3 6.7 2.3 42 3.0 0.1 2.9 4 0 0 4 4 2 0 Septin OpcA PF07239.6 KOS14833.1 - 5.2 5.9 0.0 12 4.7 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein OpcA Nairovirus_M PF07948.6 KOS14833.1 - 9.9 4.1 0.0 16 3.4 0.0 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like KilA-N PF04383.8 KOS14834.1 - 0.00034 20.2 0.0 0.00093 18.7 0.0 1.7 1 1 0 1 1 1 1 KilA-N domain DUF1786 PF08735.5 KOS14834.1 - 0.032 13.4 0.2 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) HTH_26 PF13443.1 KOS14834.1 - 0.12 12.5 0.1 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain PAT1 PF09770.4 KOS14834.1 - 3.5 5.7 26.4 4.8 5.2 18.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KOS14835.1 - 1.8e-41 141.9 0.0 3.3e-26 92.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14835.1 - 1.2e-17 63.8 0.0 3.4e-17 62.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.24 KOS14836.1 - 2.5e-40 137.7 0.0 4.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KOS14836.1 - 1.8e-27 94.9 0.1 5.6e-26 90.2 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KOS14836.1 - 2.5e-21 75.2 4.3 6.3e-21 74.0 3.0 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 KOS14836.1 - 3.9e-06 27.0 0.1 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS14836.1 - 2e-05 24.3 0.0 6.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KOS14836.1 - 4.7e-05 24.1 0.0 0.00014 22.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KOS14836.1 - 5.2e-05 22.7 0.0 0.00016 21.1 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KOS14836.1 - 7.2e-05 22.6 0.0 0.00022 21.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS14836.1 - 0.00013 21.4 0.2 0.056 12.8 0.1 2.5 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KOS14836.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KOS14836.1 - 0.00024 20.9 0.0 0.00066 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS14836.1 - 0.00027 20.9 0.1 0.0045 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KOS14836.1 - 0.00059 19.7 0.0 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KOS14836.1 - 0.0008 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KOS14836.1 - 0.0015 17.3 0.0 0.0031 16.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KOS14836.1 - 0.0032 17.6 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 KOS14836.1 - 0.0085 15.5 0.0 0.11 11.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain KaiC PF06745.8 KOS14836.1 - 0.012 14.6 0.1 2 7.5 0.0 2.4 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 KOS14836.1 - 0.019 14.1 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KOS14836.1 - 0.034 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KOS14836.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF3543 PF12063.3 KOS14836.1 - 0.038 13.1 1.0 4.5 6.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3543) AAA_24 PF13479.1 KOS14836.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS14836.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 KOS14836.1 - 0.056 13.0 0.2 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KOS14836.1 - 0.069 12.2 0.1 1.8 7.5 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KOS14836.1 - 0.07 13.4 1.4 0.095 13.0 0.0 2.0 3 0 0 3 3 1 0 AAA domain Arch_ATPase PF01637.13 KOS14836.1 - 0.08 12.6 0.4 1.2 8.7 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 KOS14836.1 - 0.11 11.6 1.1 0.24 10.6 0.0 2.0 3 0 0 3 3 2 0 PhoH-like protein Bac_DnaA PF00308.13 KOS14836.1 - 0.12 11.9 0.9 2.2 7.8 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein Torsin PF06309.6 KOS14836.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_10 PF12846.2 KOS14836.1 - 0.27 10.6 1.5 0.6 9.4 0.1 2.2 3 0 0 3 3 3 0 AAA-like domain p450 PF00067.17 KOS14837.1 - 8.8e-54 182.7 0.1 1.1e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Duo1 PF08651.5 KOS14837.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 Citrate_synt PF00285.16 KOS14838.1 - 1.4e-100 336.4 0.0 1.8e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase WD40 PF00400.27 KOS14839.1 - 5.6e-48 159.1 15.5 2e-09 36.9 0.0 11.8 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 KOS14839.1 - 9.7e-18 64.0 0.3 1.7e-17 63.2 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KOS14839.1 - 0.00017 21.3 0.1 1.5 8.5 0.1 4.8 3 1 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KOS14839.1 - 0.00025 19.3 3.5 0.13 10.4 0.1 3.9 3 1 0 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KOS14839.1 - 0.0031 16.9 0.3 0.059 12.8 0.0 2.8 1 1 1 2 2 2 1 PQQ-like domain DUF1513 PF07433.6 KOS14839.1 - 0.033 13.1 0.1 1 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Utp21 PF04192.7 KOS14840.1 - 7.3e-48 162.7 0.0 1.1e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KOS14840.1 - 1.9e-14 52.8 16.2 0.00083 19.1 0.0 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS14840.1 - 5.7e-05 22.6 0.4 0.0027 17.2 0.0 2.8 2 1 1 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 KOS14840.1 - 0.0035 15.6 1.7 0.2 9.9 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain Perilipin PF03036.11 KOS14841.1 - 1.4e-06 27.4 1.6 0.00073 18.4 0.0 2.1 2 0 0 2 2 2 2 Perilipin family LRRC37AB_C PF14914.1 KOS14841.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Apolipoprotein PF01442.13 KOS14841.1 - 0.014 14.9 4.1 0.042 13.3 2.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Carbpep_Y_N PF05388.6 KOS14841.1 - 0.032 14.3 2.3 0.42 10.7 0.0 2.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide DUF883 PF05957.8 KOS14841.1 - 0.21 11.9 2.3 7.4 7.0 0.7 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Occludin_ELL PF07303.8 KOS14841.1 - 3.5 8.3 6.7 2.6 8.8 1.8 2.6 1 1 2 3 3 3 0 Occludin homology domain Foie-gras_1 PF11817.3 KOS14844.1 - 4.5e-20 72.1 11.8 2.7e-14 53.2 0.3 2.7 2 1 1 3 3 3 2 Foie gras liver health family 1 TPR_12 PF13424.1 KOS14844.1 - 0.017 15.0 6.4 0.22 11.4 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14844.1 - 0.43 10.6 4.7 0.13 12.2 0.8 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SNARE PF05739.14 KOS14845.1 - 0.00016 21.3 0.6 0.00023 20.7 0.4 1.3 1 0 0 1 1 1 1 SNARE domain DUF2645 PF10840.3 KOS14845.1 - 0.024 14.7 0.4 0.027 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) DUF443 PF04276.7 KOS14845.1 - 0.044 13.2 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Sec20 PF03908.8 KOS14845.1 - 0.19 11.4 1.4 0.47 10.1 0.9 1.7 1 1 0 1 1 1 0 Sec20 DUF4234 PF14018.1 KOS14845.1 - 0.54 10.0 4.0 0.61 9.8 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) TRAPPC-Trs85 PF12739.2 KOS14846.1 - 1.2e-68 231.6 15.8 1.9e-68 231.0 10.9 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Scytalone_dh PF02982.9 KOS14847.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Scytalone dehydratase His_Phos_1 PF00300.17 KOS14848.1 - 1.9e-33 115.8 0.0 1.4e-32 113.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Urb2 PF10441.4 KOS14849.1 - 1.8e-30 106.2 0.5 5.7e-29 101.3 0.0 3.3 3 0 0 3 3 3 1 Urb2/Npa2 family TAFII55_N PF04658.8 KOS14850.1 - 1.1e-51 174.5 0.1 1.1e-51 174.5 0.1 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF607 PF04678.8 KOS14850.1 - 2.6 7.9 4.4 5.4 6.9 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Herpes_capsid PF06112.6 KOS14850.1 - 4.8 7.2 21.7 2.8 7.9 11.7 2.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PINIT PF14324.1 KOS14851.1 - 1.6e-34 119.0 0.2 3.1e-34 118.1 0.2 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KOS14851.1 - 2e-19 68.8 6.4 4.1e-19 67.8 4.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KOS14851.1 - 2.1e-06 27.1 1.8 4e-06 26.2 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KOS14851.1 - 0.0038 16.6 0.5 1.3 8.5 0.0 3.2 3 0 0 3 3 3 1 SAP domain zf-C3HC4_4 PF15227.1 KOS14851.1 - 0.92 9.4 4.7 1.9 8.4 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KOS14851.1 - 1.3 8.8 5.3 3 7.7 3.7 1.7 1 0 0 1 1 1 0 Ring finger domain Zds_C PF08632.5 KOS14852.1 - 5.1e-19 67.4 0.9 9.8e-19 66.4 0.6 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Smr PF01713.16 KOS14853.1 - 1.9e-11 43.9 0.0 5.8e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Smr domain SPACA7 PF15307.1 KOS14853.1 - 4.2e-05 23.6 1.4 0.0004 20.4 0.0 2.9 2 1 1 3 3 3 1 Sperm acrosome-associated protein 7 Acetate_kinase PF00871.12 KOS14853.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Acetokinase family DUF1771 PF08590.5 KOS14853.1 - 2.6 8.1 15.7 0.21 11.6 6.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1771) WH1 PF00568.18 KOS14854.1 - 1.8e-20 72.7 0.0 2.7e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KOS14854.1 - 0.009 15.5 0.1 0.028 14.0 0.0 1.9 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.8 KOS14854.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family KAR9 PF08580.5 KOS14854.1 - 5.1 5.2 8.0 7.2 4.7 5.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2841 PF11001.3 KOS14855.1 - 6.2e-36 123.0 0.6 9.7e-36 122.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HEAT PF02985.17 KOS14856.1 - 1.8e-45 148.9 21.3 0.00094 19.0 0.0 13.1 13 0 0 13 13 13 12 HEAT repeat HEAT_2 PF13646.1 KOS14856.1 - 2.8e-34 117.2 12.7 7.9e-08 32.4 0.0 7.1 2 1 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KOS14856.1 - 2.1e-15 56.8 0.9 0.0013 19.0 0.0 7.8 2 2 6 10 10 10 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KOS14856.1 - 2.5e-12 46.8 21.6 0.1 13.1 0.2 10.2 8 3 2 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.15 KOS14856.1 - 5.2e-10 38.2 5.1 6.6e-06 24.7 0.6 3.6 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KOS14856.1 - 2.3e-07 30.3 1.1 0.037 13.3 0.0 4.4 3 2 2 5 5 5 3 CLASP N terminal Arm PF00514.18 KOS14856.1 - 8.4e-07 28.5 4.3 6 6.8 0.0 7.5 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Herpes_U5 PF05999.6 KOS14856.1 - 0.0017 17.0 0.6 0.0054 15.3 0.0 1.9 2 0 0 2 2 2 1 Herpesvirus U5-like family Cnd1 PF12717.2 KOS14856.1 - 0.0059 16.4 3.5 1.6 8.5 0.1 4.7 1 1 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Ras PF00071.17 KOS14857.1 - 1.2e-56 190.5 0.0 1.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS14857.1 - 7.6e-19 68.3 0.0 1.4e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS14857.1 - 7.1e-13 48.1 0.0 8.2e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS14857.1 - 3.5e-07 30.1 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS14857.1 - 7.8e-07 28.4 0.0 9.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS14857.1 - 2.2e-06 27.2 0.0 3.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KOS14857.1 - 0.00057 20.0 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS14857.1 - 0.0013 17.9 0.1 0.0027 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KOS14857.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 KOS14857.1 - 0.0024 17.3 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KOS14857.1 - 0.0044 16.5 0.1 0.22 11.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KOS14857.1 - 0.005 16.4 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS14857.1 - 0.0058 16.3 0.0 0.022 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Septin PF00735.13 KOS14857.1 - 0.0073 15.3 0.4 0.069 12.1 0.0 2.2 2 1 0 2 2 2 1 Septin AAA_10 PF12846.2 KOS14857.1 - 0.0084 15.5 0.1 0.015 14.7 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 KOS14857.1 - 0.0091 15.7 0.1 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 KOS14857.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 KOS14857.1 - 0.017 14.5 0.0 0.042 13.2 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KOS14857.1 - 0.032 13.9 0.0 0.081 12.6 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 KOS14857.1 - 0.04 13.1 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 KOS14857.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 KOS14857.1 - 0.086 12.1 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DFP PF04127.10 KOS14858.1 - 2.3e-19 69.7 0.0 1.4e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AMP-binding PF00501.23 KOS14859.1 - 2.4e-64 217.2 0.0 4.3e-64 216.4 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme SURF4 PF02077.10 KOS14860.1 - 1.1e-97 326.5 9.4 1.3e-97 326.4 6.5 1.0 1 0 0 1 1 1 1 SURF4 family Intg_mem_TP0381 PF09529.5 KOS14860.1 - 0.0099 15.1 5.2 0.0099 15.1 3.6 2.5 2 1 0 2 2 2 1 Integral membrane protein (intg_mem_TP0381) HR_lesion PF05514.6 KOS14860.1 - 0.019 14.8 1.6 0.019 14.8 1.1 3.7 3 1 1 4 4 4 0 HR-like lesion-inducing AdoHcyase PF05221.12 KOS14861.1 - 7.4e-141 467.7 0.0 8.5e-141 467.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KOS14861.1 - 2e-83 278.1 1.6 3e-83 277.5 1.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KOS14861.1 - 9.5e-10 37.9 0.2 2.1e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KOS14861.1 - 0.0004 19.7 0.2 0.00062 19.1 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KOS14861.1 - 0.0012 18.8 0.1 0.0032 17.4 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KOS14861.1 - 0.012 15.2 0.2 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.14 KOS14861.1 - 0.028 13.5 0.3 0.21 10.6 0.2 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KOS14861.1 - 0.035 14.2 0.2 0.069 13.2 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KOS14861.1 - 0.048 13.9 0.1 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TMEM107 PF14995.1 KOS14861.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein GATA PF00320.22 KOS14862.1 - 2e-14 52.5 4.9 4e-14 51.6 3.4 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.1 KOS14862.1 - 0.12 12.1 0.7 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.1 KOS14863.1 - 9.7e-09 35.1 0.6 9.7e-09 35.1 0.4 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KOS14863.1 - 9.7e-08 31.9 13.6 2.9e-06 27.2 0.2 3.7 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS14863.1 - 6.4e-05 23.0 9.7 0.00038 20.5 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS14863.1 - 9.9e-05 22.1 2.6 0.34 10.8 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KOS14863.1 - 0.0073 16.4 2.0 3.8 7.8 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type BTV_NS2 PF04514.7 KOS14863.1 - 0.23 10.2 1.2 0.39 9.5 0.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-Di19 PF05605.7 KOS14863.1 - 0.81 9.8 3.6 3.9 7.6 0.8 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PCNA_N PF00705.13 KOS14864.1 - 6.2e-51 171.1 1.2 3.1e-50 168.9 1.2 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KOS14864.1 - 9.6e-42 141.9 0.9 1.4e-22 79.9 0.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 KOS14864.1 - 2.9e-06 26.2 0.2 0.0045 15.7 0.1 2.1 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 KOS14864.1 - 9.5e-06 24.9 0.0 1.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.7 KOS14864.1 - 0.0048 15.8 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Hus1-like protein DNA_primase_lrg PF04104.9 KOS14865.1 - 2.2e-77 259.8 0.0 3.2e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SNF2_N PF00176.18 KOS14867.1 - 4e-68 229.3 0.1 5.5e-68 228.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS14867.1 - 2.1e-07 30.6 0.0 6.8e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KOS14867.1 - 0.0006 19.5 9.7 0.0013 18.5 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS14867.1 - 0.0023 17.6 6.5 0.0052 16.4 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KOS14867.1 - 0.031 14.0 0.6 0.09 12.5 0.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KOS14867.1 - 0.046 13.3 6.7 0.11 12.2 4.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KOS14867.1 - 0.053 13.3 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 KOS14867.1 - 0.06 13.3 7.4 0.15 12.0 5.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 KOS14867.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain FA_hydroxylase PF04116.8 KOS14868.1 - 1.3e-14 54.5 14.1 1.3e-14 54.5 9.8 2.8 2 1 1 3 3 3 3 Fatty acid hydroxylase superfamily Hist_deacetyl PF00850.14 KOS14869.1 - 9.1e-92 307.6 0.4 1.4e-91 307.0 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KOS14869.1 - 5.3e-12 45.5 0.0 1.9e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Arb2 domain DUF1749 PF08538.5 KOS14869.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Tfb4 PF03850.9 KOS14870.1 - 8.1e-76 254.8 0.1 9.9e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KOS14870.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-H2C2_2 PF13465.1 KOS14871.1 - 2.1e-32 109.8 43.5 1.1e-09 38.0 0.9 7.2 7 1 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 KOS14871.1 - 1.8e-29 100.2 35.4 2.1e-06 27.6 0.3 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS14871.1 - 2.8e-20 71.0 37.8 0.00015 21.8 0.2 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS14871.1 - 4.1e-11 42.6 10.4 4.5e-05 23.4 0.1 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KOS14871.1 - 7e-08 32.1 15.2 0.00048 19.9 0.1 5.6 5 1 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.2 KOS14871.1 - 0.00017 21.6 9.5 0.5 10.6 0.0 4.7 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KOS14871.1 - 0.00022 21.2 23.6 0.002 18.1 0.6 4.9 3 1 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding RPAP2_Rtr1 PF04181.8 KOS14871.1 - 0.00071 19.6 10.3 0.51 10.4 0.5 4.8 3 1 2 5 5 5 1 Rtr1/RPAP2 family zf-C2H2_2 PF12756.2 KOS14871.1 - 0.005 16.9 14.1 0.0061 16.6 0.3 4.7 4 1 1 5 5 5 1 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KOS14871.1 - 0.035 14.1 12.1 0.51 10.3 0.1 3.7 4 0 0 4 4 3 0 zinc-finger Rep_fac-A_C PF08646.5 KOS14871.1 - 0.035 13.8 4.6 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain MBD PF01429.14 KOS14871.1 - 0.035 13.6 1.9 1.5 8.4 0.3 3.1 2 1 0 2 2 2 0 Methyl-CpG binding domain C1_4 PF07975.7 KOS14871.1 - 0.17 11.8 9.1 7.9 6.5 0.5 3.9 3 1 1 4 4 3 0 TFIIH C1-like domain zf-AN1 PF01428.11 KOS14871.1 - 0.19 11.6 5.7 14 5.6 0.6 4.1 2 1 1 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.5 KOS14871.1 - 0.28 11.1 15.9 7.3 6.6 1.2 4.6 3 2 1 4 4 4 0 Zinc ribbon domain FYDLN_acid PF09538.5 KOS14871.1 - 0.29 11.7 7.0 9.2 6.8 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2197 PF09963.4 KOS14871.1 - 0.38 10.7 4.7 2.1 8.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) XPA_N PF01286.13 KOS14871.1 - 0.45 10.2 3.3 12 5.7 0.0 3.4 3 0 0 3 3 3 0 XPA protein N-terminal zf-BED PF02892.10 KOS14871.1 - 0.61 9.8 8.7 5.8 6.7 0.5 3.2 2 0 0 2 2 2 0 BED zinc finger Rad50_zn_hook PF04423.9 KOS14871.1 - 0.66 9.4 4.0 5.2 6.6 0.1 3.0 3 1 0 3 3 2 0 Rad50 zinc hook motif C1_3 PF07649.7 KOS14871.1 - 0.99 9.4 8.0 5.2 7.1 0.2 3.5 4 0 0 4 4 3 0 C1-like domain zinc_ribbon_5 PF13719.1 KOS14871.1 - 1.7 8.3 6.5 18 5.0 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KOS14871.1 - 2.1 8.1 6.6 17 5.2 0.3 3.4 4 0 0 4 4 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KOS14871.1 - 6.3 6.2 8.5 9.1 5.6 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding DUF629 PF04780.7 KOS14871.1 - 6.3 5.1 6.8 1.4 7.3 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF629) DUF164 PF02591.10 KOS14871.1 - 7.3 6.5 8.4 3.5 7.5 0.1 3.1 4 0 0 4 4 3 0 Putative zinc ribbon domain DUF2225 PF09986.4 KOS14871.1 - 9.3 5.6 8.1 4.7 6.5 0.5 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Lipase_3 PF01764.20 KOS14872.1 - 9.1e-15 54.4 0.0 2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KOS14872.1 - 0.0072 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KOS14872.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS14872.1 - 0.52 10.1 4.8 0.14 11.9 0.5 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Snf7 PF03357.16 KOS14873.1 - 3.5e-29 101.3 15.6 3.5e-29 101.3 10.8 1.3 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KOS14873.1 - 0.44 8.3 7.0 0.58 7.9 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AF0941-like PF14591.1 KOS14873.1 - 0.5 10.4 5.0 0.26 11.3 0.7 2.3 2 1 0 2 2 2 0 AF0941-like HrpB7 PF09486.5 KOS14873.1 - 0.79 9.6 9.1 0.15 12.0 3.6 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) LUC7 PF03194.10 KOS14873.1 - 1.3 8.4 11.8 4.1 6.8 8.2 1.8 1 1 0 1 1 1 0 LUC7 N_terminus G10 PF01125.12 KOS14874.1 - 1.1e-63 213.1 3.4 1.2e-63 213.0 2.3 1.0 1 0 0 1 1 1 1 G10 protein eRF1_1 PF03463.10 KOS14875.1 - 4.5e-46 155.6 0.0 8.2e-46 154.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KOS14875.1 - 8e-21 74.4 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KOS14875.1 - 2.6e-20 73.0 0.0 4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 YliH PF10799.3 KOS14875.1 - 0.092 12.4 0.1 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DUF2346 PF09803.4 KOS14876.1 - 2.7e-09 36.7 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF605 PF04652.11 KOS14877.1 - 7.8 5.7 24.7 11 5.2 17.1 1.3 1 0 0 1 1 1 0 Vta1 like CN_hydrolase PF00795.17 KOS14878.1 - 4.5e-22 78.3 0.0 6.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA_16 PF13191.1 KOS14879.1 - 8e-11 42.2 5.3 3.2e-08 33.7 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 KOS14879.1 - 2.2e-10 40.8 0.0 9.6e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS14879.1 - 4.5e-09 36.5 0.1 2.5e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS14879.1 - 0.00055 19.6 0.1 0.017 14.8 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KOS14879.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KOS14879.1 - 0.0017 17.9 2.0 0.0055 16.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KOS14879.1 - 0.0055 16.6 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KOS14879.1 - 0.013 15.1 0.1 0.045 13.4 0.1 2.0 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 KOS14879.1 - 0.016 14.5 0.1 0.089 12.2 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KOS14879.1 - 0.017 14.2 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 KOS14879.1 - 0.028 13.3 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 KOS14879.1 - 0.044 12.7 0.0 0.096 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KOS14879.1 - 0.06 13.0 0.6 0.14 11.8 0.0 1.9 2 1 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 KOS14879.1 - 0.098 12.3 0.0 0.51 9.9 0.0 1.9 1 1 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 KOS14879.1 - 0.14 11.5 0.0 0.71 9.2 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.8 KOS14879.1 - 0.23 10.1 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KOS14879.1 - 0.39 10.5 0.0 0.39 10.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain zf-CCHC PF00098.18 KOS14880.1 - 5.3e-06 26.1 1.3 5.3e-06 26.1 0.9 6.5 7 1 0 7 7 7 3 Zinc knuckle zf-CCHC_4 PF14392.1 KOS14880.1 - 0.0024 17.5 0.8 0.0024 17.5 0.5 4.9 4 1 1 5 5 5 2 Zinc knuckle zf-CCHC_6 PF15288.1 KOS14880.1 - 0.03 14.0 2.0 0.03 14.0 1.4 4.4 3 2 1 4 4 4 0 Zinc knuckle zf-ribbon_3 PF13248.1 KOS14880.1 - 0.68 9.2 20.0 2.1 7.6 3.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-dskA_traR PF01258.12 KOS14880.1 - 1.8 8.3 12.1 6.8 6.5 0.2 4.2 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DUF4614 PF15391.1 KOS14881.1 - 1.1 9.0 11.5 1.3 8.7 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF566 PF04484.7 KOS14881.1 - 1.6 8.1 15.7 2.1 7.7 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Herpes_BLLF1 PF05109.8 KOS14881.1 - 9.1 4.1 27.6 10 3.9 19.1 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ThiF PF00899.16 KOS14883.1 - 3.5e-13 49.5 0.1 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family IPP-2 PF04979.9 KOS14884.1 - 1.9e-07 31.3 8.5 3.6e-05 24.0 5.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) PHD PF00628.24 KOS14885.1 - 8.3e-10 38.2 8.5 1.8e-09 37.1 5.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 KOS14885.1 - 0.00014 21.3 0.2 0.00014 21.3 0.1 2.2 3 1 0 3 3 3 1 CpG binding protein zinc finger C terminal domain C1_1 PF00130.17 KOS14885.1 - 0.0067 16.1 2.7 0.019 14.6 1.9 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KOS14885.1 - 0.2 11.0 3.4 0.43 9.9 2.3 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KOS14885.1 - 2 8.2 13.7 0.14 11.9 3.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 NTP_transferase PF00483.18 KOS14886.1 - 2.4e-42 144.9 0.0 3.8e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KOS14886.1 - 5.4e-09 36.3 0.1 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 KOS14886.1 - 2.6e-06 27.1 0.1 4.6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 KOS14886.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF1741 PF08427.5 KOS14889.1 - 4.3e-25 88.5 0.2 1.3e-24 87.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Sugar_tr PF00083.19 KOS14890.1 - 4.3e-23 81.6 28.6 1.4e-18 66.7 6.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KOS14890.1 - 2.9e-15 55.8 42.0 8.8e-15 54.2 29.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KOS14891.1 - 5.2e-20 71.4 28.8 5.2e-20 71.4 19.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS14891.1 - 1.8e-15 56.5 22.1 4.2e-13 48.6 4.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Pex24p PF06398.6 KOS14892.1 - 6.9e-25 87.6 5.1 3.5e-24 85.2 3.5 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Sugar_tr PF00083.19 KOS14893.1 - 1.5e-19 69.9 29.5 5.2e-18 64.8 20.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS14893.1 - 4.8e-17 61.7 42.5 1.4e-16 60.1 28.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily BRO1 PF03097.13 KOS14894.1 - 3.3e-70 236.7 1.4 3.4e-70 236.7 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KOS14894.1 - 4.9e-25 88.1 1.5 7.2e-25 87.5 1.0 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV G-patch PF01585.18 KOS14895.1 - 1.6e-12 46.9 2.0 6e-12 45.1 1.4 2.1 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 KOS14895.1 - 4.6e-12 45.4 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 KOS14895.1 - 2.4e-05 24.0 0.8 2.4e-05 24.0 0.6 3.2 4 0 0 4 4 4 1 DExH-box splicing factor binding site DUF1769 PF08588.5 KOS14896.1 - 2.4e-16 59.4 0.4 5.1e-16 58.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) BRAP2 PF07576.7 KOS14897.1 - 2.2e-14 52.9 0.0 1.2e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 AF0941-like PF14591.1 KOS14897.1 - 0.044 13.8 2.9 0.11 12.5 0.2 2.4 2 1 0 2 2 2 0 AF0941-like RHD3 PF05879.7 KOS14897.1 - 0.056 11.3 12.1 0.078 10.8 8.4 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CPW_WPC PF09717.5 KOS14897.1 - 0.44 11.2 3.5 0.8 10.3 0.9 2.2 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) HAUS6_N PF14661.1 KOS14897.1 - 0.45 9.8 13.8 0.77 9.0 9.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1515 PF07439.6 KOS14897.1 - 0.45 10.3 2.1 1 9.1 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.10 KOS14897.1 - 0.94 8.6 10.9 1.5 7.9 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.7 KOS14897.1 - 1.3 9.3 8.2 3.9 7.8 0.1 3.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KOS14897.1 - 1.7 8.7 13.3 5.2 7.1 1.2 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 KOS14897.1 - 3.3 7.6 24.5 5.1 7.0 13.9 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.6 KOS14897.1 - 5.1 6.5 18.6 3.4 7.0 2.2 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 SURF6 PF04935.7 KOS14898.1 - 3.8e-39 134.1 28.3 3.8e-39 134.1 19.6 2.3 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 KOS14898.1 - 1.4e-12 47.4 5.5 1.4e-12 47.4 3.8 4.6 4 1 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Myc_N PF01056.13 KOS14898.1 - 0.9 8.6 18.7 0.0079 15.3 6.7 2.2 2 1 0 2 2 2 0 Myc amino-terminal region TRAM_LAG1_CLN8 PF03798.11 KOS14899.1 - 7.2e-33 113.8 23.2 7.2e-33 113.8 16.1 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KOS14899.1 - 0.00014 21.3 2.7 0.00099 18.5 0.0 2.7 2 0 0 2 2 2 1 TRAM1-like protein SHNi-TPR PF10516.4 KOS14900.1 - 4.8e-12 44.9 0.1 1.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 KOS14900.1 - 7.1e-09 35.4 3.8 0.00049 19.9 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KOS14900.1 - 0.00042 19.9 1.7 0.043 13.4 0.1 2.4 2 0 0 2 2 2 2 TPR repeat YfdX PF10938.3 KOS14900.1 - 0.059 13.0 2.2 0.073 12.7 0.1 2.1 2 0 0 2 2 2 0 YfdX protein TPR_16 PF13432.1 KOS14900.1 - 0.27 11.9 6.4 4.7 7.9 0.7 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KOS14900.1 - 0.49 10.4 4.9 0.5 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CHASE3 PF05227.8 KOS14900.1 - 5.4 6.6 8.9 6 6.5 3.5 2.6 2 1 1 3 3 3 0 CHASE3 domain La PF05383.12 KOS14901.1 - 3.7e-16 58.6 0.1 5.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 La domain NAD_binding_1 PF00175.16 KOS14902.1 - 4.5e-07 30.4 0.0 6.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KOS14902.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KOS14902.1 - 0.031 14.1 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain WD40 PF00400.27 KOS14903.1 - 1.1e-22 79.0 21.6 1.7e-06 27.6 0.0 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 KOS14903.1 - 2.7e-15 56.1 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Gpi16 PF04113.9 KOS14904.1 - 3.8e-100 335.5 0.4 5.5e-51 173.2 0.8 2.1 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component DEAD PF00270.24 KOS14905.1 - 8e-45 152.3 0.1 1.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS14905.1 - 7.7e-21 73.7 0.0 2.4e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KOS14905.1 - 1.1e-20 72.9 0.5 2.4e-20 71.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KOS14905.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit L51_S25_CI-B8 PF05047.11 KOS14907.1 - 4.4e-11 42.3 0.0 5.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NicO PF03824.11 KOS14908.1 - 9.6e-43 146.5 4.4 9.6e-43 146.5 3.1 3.7 3 2 0 3 3 3 1 High-affinity nickel-transport protein DUF3357 PF11837.3 KOS14908.1 - 0.019 14.8 0.7 49 3.8 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3357) WRW PF10206.4 KOS14908.1 - 0.14 12.1 0.2 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Cupin_8 PF13621.1 KOS14910.1 - 2.1e-31 109.3 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KOS14910.1 - 5e-06 26.7 0.1 5.2e-05 23.4 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KOS14910.1 - 1.5e-05 24.3 0.3 0.0003 20.1 0.0 2.7 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 KOS14910.1 - 0.084 12.3 0.0 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Med20 PF08612.6 KOS14911.1 - 1.3e-06 27.7 0.0 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex XkdW PF09636.5 KOS14911.1 - 0.3 10.9 0.9 1.3 8.8 0.3 2.0 2 0 0 2 2 2 0 XkdW protein ThiF PF00899.16 KOS14912.1 - 1.4e-42 144.7 0.3 2.5e-42 143.9 0.2 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KOS14912.1 - 4.5e-22 77.4 0.0 1e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KOS14912.1 - 4.7e-06 26.7 0.1 8.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KOS14912.1 - 0.00011 21.3 0.5 0.00016 20.7 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KOS14912.1 - 0.0011 19.2 0.1 0.002 18.3 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 KOS14912.1 - 0.0016 17.4 0.2 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS14912.1 - 0.06 13.7 0.2 0.51 10.7 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KOS14912.1 - 0.087 12.2 0.4 0.15 11.4 0.3 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KOS14912.1 - 0.11 11.5 0.7 0.15 11.0 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KOS14912.1 - 0.11 12.0 0.2 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DnaJ_CXXCXGXG PF00684.14 KOS14913.1 - 5.9e-06 26.2 3.8 0.0051 16.8 0.4 2.3 2 0 0 2 2 2 2 DnaJ central domain OrfB_Zn_ribbon PF07282.6 KOS14913.1 - 0.056 13.1 0.9 9.4 5.9 0.3 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain IPK PF03770.11 KOS14914.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase AD PF09793.4 KOS14915.1 - 3.8e-13 49.0 0.0 6.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Vps55 PF04133.9 KOS14916.1 - 2.1e-33 114.5 7.3 2.5e-33 114.3 5.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF1469 PF07332.6 KOS14916.1 - 9.4 5.9 15.9 0.71 9.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF21 PF01595.15 KOS14917.1 - 3e-34 117.9 1.0 4.7e-34 117.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KOS14917.1 - 0.00043 20.0 0.3 13 5.6 0.0 3.7 3 0 0 3 3 3 3 CBS domain AAA PF00004.24 KOS14918.1 - 2.5e-56 189.5 0.0 2e-43 147.7 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KOS14918.1 - 2e-24 85.4 0.5 5.2e-24 84.0 0.3 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KOS14918.1 - 4.8e-09 36.4 14.0 0.0071 16.3 0.1 5.9 2 2 3 6 6 6 2 AAA ATPase domain IstB_IS21 PF01695.12 KOS14918.1 - 1.7e-08 34.1 0.4 0.00016 21.1 0.0 3.0 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 KOS14918.1 - 1.9e-07 31.9 0.3 0.0063 17.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KOS14918.1 - 3.2e-07 29.9 12.8 0.0081 15.5 0.1 5.3 3 2 2 5 5 5 3 AAA domain RuvB_N PF05496.7 KOS14918.1 - 4.2e-06 25.9 0.0 0.0023 16.9 0.0 2.9 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KOS14918.1 - 7.2e-06 25.0 0.0 0.0063 15.4 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.1 KOS14918.1 - 7.7e-06 25.8 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KOS14918.1 - 1e-05 25.4 1.3 0.046 13.6 0.0 4.0 4 1 0 4 4 3 1 AAA domain AAA_22 PF13401.1 KOS14918.1 - 1.2e-05 25.4 6.2 0.24 11.5 0.0 5.0 4 2 2 6 6 5 2 AAA domain NACHT PF05729.7 KOS14918.1 - 2e-05 24.3 1.3 0.077 12.6 0.1 4.0 3 1 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 KOS14918.1 - 3.5e-05 23.0 0.6 0.18 10.8 0.1 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 KOS14918.1 - 5.5e-05 22.8 0.2 0.47 10.2 0.1 3.4 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 KOS14918.1 - 8.1e-05 21.8 2.5 0.12 11.4 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS14918.1 - 8.6e-05 22.2 0.3 0.33 10.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KOS14918.1 - 0.00012 20.8 0.1 0.074 11.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 KOS14918.1 - 0.00016 21.2 0.0 0.029 13.8 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KOS14918.1 - 0.00017 21.6 0.0 0.76 9.8 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 KOS14918.1 - 0.00019 21.7 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KOS14918.1 - 0.00028 20.8 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KOS14918.1 - 0.00032 19.9 0.0 0.059 12.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Bac_DnaA PF00308.13 KOS14918.1 - 0.00039 20.1 0.0 0.056 13.0 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.17 KOS14918.1 - 0.0014 18.7 0.0 0.72 10.0 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.1 KOS14918.1 - 0.0065 16.4 1.2 3.9 7.3 0.0 3.2 2 1 1 3 3 3 0 AAA domain UPF0079 PF02367.12 KOS14918.1 - 0.0066 16.0 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KOS14918.1 - 0.0094 16.2 0.2 2.8 8.2 0.0 2.8 3 0 0 3 3 2 1 ABC transporter NB-ARC PF00931.17 KOS14918.1 - 0.012 14.5 0.0 1.4 7.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_29 PF13555.1 KOS14918.1 - 0.013 15.0 0.2 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KOS14918.1 - 0.015 15.6 0.1 0.076 13.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KOS14918.1 - 0.052 13.1 1.9 3.7 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KOS14918.1 - 0.058 12.4 0.2 7.5 5.5 0.0 2.5 3 0 0 3 3 2 0 KaiC PduV-EutP PF10662.4 KOS14918.1 - 0.074 12.5 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KOS14918.1 - 0.075 11.9 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KOS14918.1 - 0.097 12.3 0.1 15 5.2 0.0 3.1 4 0 0 4 4 3 0 NTPase Cytidylate_kin2 PF13189.1 KOS14918.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.17 KOS14918.1 - 0.1 12.4 0.9 0.45 10.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.10 KOS14918.1 - 0.11 11.1 0.0 1.8 7.1 0.0 2.3 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 KOS14918.1 - 0.13 11.9 0.3 5.3 6.6 0.1 3.1 2 1 1 3 3 3 0 Adenylylsulphate kinase Arch_ATPase PF01637.13 KOS14918.1 - 0.13 11.9 0.0 32 4.0 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase DUF2075 PF09848.4 KOS14918.1 - 0.28 10.1 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) LETM1 PF07766.8 KOS14919.1 - 4.8e-87 291.3 1.1 4.8e-87 291.3 0.8 2.1 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 KOS14919.1 - 0.00017 21.6 1.9 0.011 15.8 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KOS14919.1 - 0.00055 19.5 0.1 0.024 14.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.1 KOS14919.1 - 0.064 13.1 1.7 0.79 9.6 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain SKN1 PF03935.10 KOS14920.1 - 8.6e-184 611.3 6.5 1e-183 611.1 4.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ABC_membrane PF00664.18 KOS14921.1 - 1.6e-65 221.2 24.5 4.2e-35 121.5 8.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS14921.1 - 1.2e-48 164.9 0.2 4.1e-30 104.8 0.0 3.2 3 1 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.18 KOS14921.1 - 4e-05 23.5 0.0 0.098 12.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 KOS14921.1 - 9e-05 21.8 3.7 0.15 11.3 0.2 3.8 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KOS14921.1 - 9.9e-05 22.4 1.3 0.015 15.3 0.3 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KOS14921.1 - 0.00011 21.6 0.1 0.36 10.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KOS14921.1 - 0.002 17.9 0.1 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 KOS14921.1 - 0.0025 17.2 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KOS14921.1 - 0.0026 17.5 0.9 0.24 11.1 0.1 2.9 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 KOS14921.1 - 0.009 15.5 0.0 0.93 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_21 PF13304.1 KOS14921.1 - 0.013 15.4 0.1 1.6 8.6 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.1 KOS14921.1 - 0.014 16.1 0.0 0.075 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KOS14921.1 - 0.016 14.0 0.1 0.077 11.7 0.0 2.0 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KOS14921.1 - 0.019 15.4 2.1 7.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Miro-like protein DUF258 PF03193.11 KOS14921.1 - 0.019 14.1 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KOS14921.1 - 0.034 13.5 0.1 4.1 6.7 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.17 KOS14921.1 - 0.07 11.9 0.6 3.1 6.5 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.1 KOS14921.1 - 0.13 12.6 0.1 24 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KOS14921.1 - 0.17 11.5 0.3 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KOS14921.1 - 0.18 12.0 0.0 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP-synt_E PF05680.7 KOS14922.1 - 1.3e-22 79.5 0.0 1.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain LdpA_C PF12617.3 KOS14922.1 - 0.01 15.1 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal ABC_tran_2 PF12848.2 KOS14922.1 - 0.016 15.0 0.8 0.019 14.7 0.6 1.2 1 0 0 1 1 1 0 ABC transporter Caudo_TAP PF02413.12 KOS14922.1 - 0.056 13.6 0.9 0.069 13.3 0.7 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein GSH-S_N PF02951.9 KOS14922.1 - 0.084 12.6 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain TRM PF02005.11 KOS14923.1 - 7.6e-113 377.2 0.0 5.8e-111 371.0 0.0 2.0 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PPK2 PF03976.9 KOS14923.1 - 0.034 13.4 0.2 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RRM_1 PF00076.17 KOS14924.1 - 6.9e-13 48.0 0.1 2.3e-12 46.3 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS14924.1 - 1.1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14924.1 - 2.5e-06 27.2 0.0 5.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 KOS14925.1 - 8.7e-15 54.6 0.5 1e-14 54.3 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Antimicrobial_7 PF08102.6 KOS14925.1 - 0.017 15.1 0.2 0.033 14.2 0.2 1.5 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Gp37 PF09646.5 KOS14925.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Gp37 protein Pkinase PF00069.20 KOS14926.1 - 4e-74 249.0 0.1 4e-74 249.0 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14926.1 - 5.3e-53 179.7 0.2 5.3e-53 179.7 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KOS14926.1 - 1.1e-20 73.8 0.0 3.5e-20 72.1 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 KOS14926.1 - 1.6e-11 44.3 1.0 4.2e-11 42.9 0.7 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 KOS14926.1 - 3.1e-08 32.9 0.1 6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KOS14926.1 - 0.00031 20.9 1.6 0.019 15.1 1.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 KOS14926.1 - 0.12 12.0 0.1 0.12 12.0 0.0 3.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family Caldesmon PF02029.10 KOS14926.1 - 0.77 8.1 5.8 1.3 7.3 4.0 1.2 1 0 0 1 1 1 0 Caldesmon ATP-synt_ab PF00006.20 KOS14927.1 - 3.4e-69 232.6 0.0 5.8e-69 231.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KOS14927.1 - 8.9e-23 80.9 0.3 2.7e-22 79.3 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KOS14927.1 - 5.1e-19 68.2 2.7 8.7e-19 67.5 1.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KOS14927.1 - 3e-05 23.8 1.5 6.9e-05 22.6 1.1 1.6 1 0 0 1 1 1 1 HAS barrel domain FmdE PF02663.9 KOS14927.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Dus PF01207.12 KOS14928.1 - 4.4e-47 160.4 0.0 7.7e-37 126.7 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF849 PF05853.7 KOS14928.1 - 0.048 12.5 0.5 0.096 11.5 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Ribosomal_L21e PF01157.13 KOS14929.1 - 1.1e-35 121.4 4.2 5.1e-35 119.2 2.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e SH3_2 PF07653.12 KOS14929.1 - 0.007 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HSP70 PF00012.15 KOS14930.1 - 3.2e-73 246.6 0.3 4.2e-73 246.2 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS14930.1 - 4.6e-08 32.0 0.2 1.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 KOS14930.1 - 0.00093 18.1 0.1 0.012 14.5 0.1 2.4 2 1 0 2 2 2 1 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.13 KOS14930.1 - 0.0022 17.1 0.3 0.28 10.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FtsA PF14450.1 KOS14930.1 - 0.021 14.6 0.6 5.3 6.9 0.0 3.3 3 1 0 3 3 3 0 Cell division protein FtsA HAD_2 PF13419.1 KOS14931.1 - 8.4e-14 52.1 0.0 2.1e-09 37.8 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS14931.1 - 3e-10 40.8 0.0 5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KOS14931.1 - 0.0048 16.7 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KOS14931.1 - 0.019 14.6 0.0 0.094 12.4 0.0 2.2 2 0 0 2 2 2 0 HAD-hyrolase-like HAD PF12710.2 KOS14931.1 - 0.084 13.0 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EspF PF04806.7 KOS14931.1 - 0.18 11.9 0.1 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 EspF protein repeat Pkinase PF00069.20 KOS14932.1 - 7.5e-72 241.5 0.0 8.4e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14932.1 - 5.2e-32 110.9 0.0 6.4e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14932.1 - 0.00031 19.8 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS14932.1 - 0.00061 19.6 0.1 0.0021 17.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KOS14932.1 - 0.0095 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KOS14932.1 - 0.027 13.5 0.1 0.075 12.0 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cellulase PF00150.13 KOS14933.1 - 2.5e-16 59.7 0.0 7.3e-08 31.9 0.0 3.2 3 0 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) Mt_ATP-synt_B PF05405.9 KOS14934.1 - 4.1e-45 153.1 5.2 5.1e-45 152.8 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DASH_Duo1 PF08651.5 KOS14934.1 - 0.1 12.1 2.9 3.4 7.2 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 PBP_sp32 PF07222.7 KOS14934.1 - 1.3 8.1 5.5 2 7.5 3.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Med26 PF08711.6 KOS14935.1 - 1.3e-06 27.7 0.0 3.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_L18e PF00828.14 KOS14937.1 - 5.3e-31 107.6 0.1 7.2e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Rep_fac-A_C PF08646.5 KOS14938.1 - 2.6e-50 169.9 0.0 3.5e-47 159.7 0.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KOS14938.1 - 1.1e-26 92.5 0.8 2.2e-26 91.5 0.6 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KOS14938.1 - 6.6e-13 48.3 0.0 4.9e-10 39.1 0.0 3.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 KOS14938.1 - 0.086 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 Endonuclease_NS PF01223.18 KOS14939.1 - 4.1e-51 173.5 0.0 5.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.27 KOS14940.1 - 1.7e-11 43.5 9.7 0.027 14.3 0.0 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat VHS PF00790.14 KOS14942.1 - 3e-32 111.1 0.2 3e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KOS14942.1 - 7.1e-17 61.0 9.8 1.4e-16 60.1 6.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KOS14942.1 - 3.1e-07 29.3 8.3 2.7e-05 23.3 1.0 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 KOS14942.1 - 0.0074 16.1 3.9 0.014 15.2 2.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger OAD_gamma PF04277.8 KOS14942.1 - 1.7 9.0 6.8 2e+02 2.4 4.7 2.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain IBR PF01485.16 KOS14942.1 - 3.3 7.6 9.5 14 5.6 6.7 1.8 1 1 0 1 1 1 0 IBR domain LSM14 PF12701.2 KOS14943.1 - 1.8e-26 91.7 0.0 4.3e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KOS14943.1 - 1.1e-09 38.7 7.5 1.1e-09 38.7 5.2 2.8 2 2 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KOS14943.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 KOS14943.1 - 0.0092 14.5 4.6 0.016 13.7 3.2 1.4 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DUF3827 PF12877.2 KOS14943.1 - 2 6.3 11.4 2.9 5.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Macoilin PF09726.4 KOS14943.1 - 7.8 4.6 10.8 10 4.2 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Cellulase PF00150.13 KOS14944.1 - 3.3e-17 62.5 3.3 7.3e-17 61.4 2.3 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 KOS14944.1 - 0.069 12.4 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Neur_chan_memb PF02932.11 KOS14944.1 - 0.13 12.1 5.4 0.29 10.9 3.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 KOS14944.1 - 0.17 10.8 11.3 0.25 10.2 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GHMP_kinases_N PF00288.21 KOS14945.1 - 1.6e-13 50.4 3.2 4.8e-13 48.9 2.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS14945.1 - 2.6e-06 27.5 0.0 5.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal FliT PF05400.8 KOS14946.1 - 0.35 11.2 7.4 0.4 11.1 3.9 1.9 2 1 1 3 3 3 0 Flagellar protein FliT RhoGAP PF00620.22 KOS14947.1 - 3.2e-40 137.2 0.1 1.1e-39 135.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 KOS14947.1 - 2.6e-10 40.3 0.0 1.7e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KOS14947.1 - 3.5e-08 33.4 0.0 1.2e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.24 KOS14947.1 - 0.039 14.1 0.0 15 5.8 0.0 2.5 2 0 0 2 2 2 0 PH domain DUF3325 PF11804.3 KOS14948.1 - 0.011 15.6 3.9 0.031 14.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Coiled-coil_56 PF09813.4 KOS14949.1 - 0.00049 20.0 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF155 PF02582.9 KOS14950.1 - 8.7e-51 172.2 0.1 8.7e-51 172.2 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF218 PF02698.12 KOS14951.1 - 0.0024 17.3 0.0 0.025 14.0 0.0 2.1 1 1 0 2 2 2 1 DUF218 domain His_biosynth PF00977.16 KOS14952.1 - 1.1e-42 145.8 0.0 1.5e-24 86.5 0.0 2.9 2 2 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 KOS14952.1 - 2.1e-23 82.7 0.0 3.1e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KOS14952.1 - 1.9e-11 43.8 0.0 5.5e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KOS14952.1 - 1.4e-10 41.1 0.0 8e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 KOS14952.1 - 0.0056 16.1 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 WGG PF10273.4 KOS14953.1 - 7.2e-21 74.0 0.0 1.3e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3425 PF11905.3 KOS14953.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) CLASP_N PF12348.3 KOS14954.1 - 1.2e-31 109.8 0.0 1.6e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 KOS14954.1 - 0.0069 16.6 0.4 0.018 15.2 0.3 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 KOS14954.1 - 0.026 14.6 1.4 0.048 13.7 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat GDI PF00996.13 KOS14955.1 - 1.2e-53 181.9 0.0 5e-53 179.9 0.0 1.7 1 1 0 1 1 1 1 GDP dissociation inhibitor OHCU_decarbox PF09349.5 KOS14956.1 - 2.9e-07 30.9 0.0 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 2 OHCU decarboxylase COG4 PF08318.7 KOS14958.1 - 7.7e-30 103.7 0.0 1.6e-29 102.6 0.0 1.5 1 1 0 1 1 1 1 COG4 transport protein SET PF00856.23 KOS14960.1 - 7.7e-05 23.0 0.0 0.0031 17.8 0.0 2.6 1 1 0 1 1 1 1 SET domain LRR_8 PF13855.1 KOS14962.1 - 3.3e-28 97.2 2.1 1.4e-09 37.5 0.4 6.2 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 KOS14962.1 - 3.1e-25 87.3 0.1 0.00011 21.7 0.0 8.1 4 3 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS14962.1 - 3.1e-12 44.7 10.8 0.97 9.7 0.0 10.4 10 2 1 11 11 11 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS14962.1 - 5.7e-10 37.7 13.4 7.9 7.1 0.1 10.2 9 1 1 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 KOS14962.1 - 2.9e-05 23.6 1.7 0.5 9.9 0.1 3.6 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 KOS14962.1 - 9.4e-05 22.1 1.4 50 4.4 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich repeat RhoGEF PF00621.15 KOS14963.1 - 1.3e-22 80.5 0.0 2.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain MatE PF01554.13 KOS14965.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 MatE DUF2269 PF10027.4 KOS14965.1 - 1.2 8.8 4.1 3.2 7.5 0.3 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) CactinC_cactus PF09732.4 KOS14966.1 - 7.1e-55 183.9 3.5 1.1e-54 183.3 2.4 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KOS14966.1 - 3.7e-46 156.8 1.8 9.2e-46 155.5 1.2 1.7 1 0 0 1 1 1 1 Conserved mid region of cactin Pkinase PF00069.20 KOS14967.1 - 4.6e-41 140.7 0.0 1.8e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14967.1 - 1.4e-22 80.0 0.0 1.3e-14 53.9 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KOS14967.1 - 0.037 13.7 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.18 KOS14968.1 - 2.7e-107 358.3 0.0 3.7e-107 357.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain ICMT PF04140.9 KOS14968.1 - 3.5e-25 88.0 0.7 7.7e-25 86.9 0.5 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KOS14968.1 - 1.4e-11 44.4 1.8 1.4e-11 44.4 1.2 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ECF-ribofla_trS PF07155.7 KOS14968.1 - 0.0087 15.8 1.3 0.017 14.8 0.9 1.4 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component DUF904 PF06005.7 KOS14968.1 - 0.013 15.7 1.1 0.029 14.6 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) PRAI PF00697.17 KOS14968.1 - 0.028 13.9 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF1295 PF06966.7 KOS14968.1 - 0.05 12.8 4.5 0.031 13.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Ribosomal_S6e PF01092.14 KOS14969.1 - 4.8e-53 178.1 0.1 4.8e-53 178.1 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e AATase PF07247.7 KOS14970.1 - 0.034 12.7 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase SRR1 PF07985.7 KOS14970.1 - 0.17 11.8 0.1 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 SRR1 DEP PF00610.16 KOS14971.1 - 0.00042 19.9 0.1 0.082 12.6 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PCI PF01399.22 KOS14971.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 PCI domain RGS PF00615.14 KOS14971.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Regulator of G protein signaling domain UTP15_C PF09384.5 KOS14972.1 - 1.2e-44 151.5 0.0 2.1e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KOS14972.1 - 4.1e-30 102.5 1.3 5.7e-07 29.1 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KOS14972.1 - 0.0015 16.7 0.5 0.62 8.1 0.0 3.1 2 2 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KOS14972.1 - 0.028 12.7 0.0 0.08 11.2 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain AMP-binding PF00501.23 KOS14973.1 - 2.8e-92 309.2 0.1 3.4e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS14973.1 - 2.5e-21 76.3 0.2 1.8e-20 73.6 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DnaJ PF00226.26 KOS14974.1 - 6.4e-23 80.2 0.9 1.2e-22 79.3 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS14974.1 - 7.7e-23 80.1 0.0 2.5e-20 72.1 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KOS14974.1 - 5.4e-15 55.1 20.0 9e-15 54.4 13.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KOS14974.1 - 0.00068 19.2 7.0 0.24 11.1 1.2 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_C PF00034.16 KOS14974.1 - 0.041 14.6 1.5 5.1 8.0 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c Paired_CXXCH_1 PF09699.5 KOS14974.1 - 0.061 12.8 3.4 1.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.1 KOS14974.1 - 0.069 12.7 12.3 0.37 10.4 8.7 2.1 1 1 0 1 1 1 0 Cytochrome c7 SUV3_C PF12513.3 KOS14974.1 - 0.077 12.4 0.2 5.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal Cytochrom_c3_2 PF14537.1 KOS14974.1 - 0.16 12.2 13.2 0.72 10.2 8.8 2.2 1 1 2 3 3 3 0 Cytochrome c3 DUF1924 PF09086.6 KOS14974.1 - 1.1 9.3 7.2 1.7 8.7 0.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrom_CIII PF02085.11 KOS14974.1 - 1.8 8.7 11.5 18 5.4 7.9 2.3 1 1 0 1 1 1 0 Class III cytochrome C family zinc-ribbons_6 PF07191.7 KOS14974.1 - 2.9 7.7 9.2 3.2 7.5 2.0 2.3 2 0 0 2 2 2 0 zinc-ribbons Cytochrome_CBB3 PF13442.1 KOS14974.1 - 5.6 7.1 11.6 7.6 6.7 1.8 3.2 2 1 1 3 3 2 0 Cytochrome C oxidase, cbb3-type, subunit III DMRL_synthase PF00885.14 KOS14975.1 - 9.9e-48 161.4 0.0 1.1e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase His_Phos_1 PF00300.17 KOS14976.1 - 5.3e-13 49.3 0.0 5.9e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Adaptin_N PF01602.15 KOS14977.1 - 1.6e-53 181.8 0.1 1.8e-53 181.6 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region CoA_trans PF01144.18 KOS14978.1 - 7.5e-99 329.2 1.4 3.6e-59 199.5 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KOS14978.1 - 0.084 12.5 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Ribosomal_L14 PF00238.14 KOS14979.1 - 1.6e-42 144.1 0.3 1.8e-42 143.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NAC PF01849.13 KOS14980.1 - 2.4e-20 71.7 0.1 4.5e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 NAC domain D123 PF07065.9 KOS14981.1 - 3.4e-78 262.7 0.0 4e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KOS14981.1 - 0.0016 18.3 0.0 0.029 14.2 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4343) BNR_2 PF13088.1 KOS14982.1 - 2.7e-08 33.4 4.2 0.096 11.9 0.0 6.0 5 2 1 6 6 6 3 BNR repeat-like domain BNR PF02012.15 KOS14982.1 - 5.9e-07 28.3 45.4 0.53 10.3 0.4 11.0 10 0 0 10 10 10 7 BNR/Asp-box repeat PSII_BNR PF14870.1 KOS14982.1 - 0.00054 19.0 1.2 0.21 10.5 0.0 3.7 4 1 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 Mad3_BUB1_I PF08311.7 KOS14983.1 - 1.8e-08 34.1 11.7 0.049 13.4 1.5 7.8 6 2 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.1 KOS14983.1 - 2.4e-07 30.5 12.6 4.1 7.3 0.1 7.6 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KOS14983.1 - 2.7e-07 30.1 12.2 4.4 7.0 0.0 7.9 6 1 2 9 9 9 2 TPR repeat TPR_19 PF14559.1 KOS14983.1 - 6.2e-06 26.4 8.0 4.2 7.7 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.5 KOS14983.1 - 0.00014 20.8 13.4 0.002 17.0 0.0 5.8 4 1 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 KOS14983.1 - 0.00045 20.8 28.2 0.69 10.6 0.0 8.9 9 1 2 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS14983.1 - 0.0013 18.5 13.3 9.1 6.4 0.1 9.2 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_17 PF13431.1 KOS14983.1 - 0.0046 17.0 6.4 12 6.4 0.0 6.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KOS14983.1 - 0.0059 17.1 37.9 6.4 7.7 0.0 13.7 13 3 4 17 17 14 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS14983.1 - 0.018 14.8 14.2 24 5.0 0.0 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 KOS14983.1 - 0.066 13.6 5.0 6.1 7.5 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat R3H PF01424.17 KOS14984.1 - 3e-13 49.2 0.2 6.2e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 KOS14984.1 - 7.6e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS14984.1 - 4.1e-07 29.5 0.0 7.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS14984.1 - 2.6e-05 23.9 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KOS14985.1 - 2.4e-61 207.2 0.0 2.7e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KOS14985.1 - 0.029 13.8 1.9 0.58 9.7 0.0 2.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Guanylate_kin PF00625.16 KOS14986.1 - 7.7e-59 198.2 0.0 1.1e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 KOS14986.1 - 2.2e-08 34.3 0.1 2.2e-07 31.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KOS14986.1 - 1.3e-06 28.3 0.0 1.1e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS14986.1 - 7.3e-06 26.1 0.0 2.5e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS14986.1 - 7.6e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KOS14986.1 - 0.00015 22.5 0.0 0.0004 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KOS14986.1 - 0.00039 20.7 0.0 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Acetyltransf_1 PF00583.19 KOS14986.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RNA_helicase PF00910.17 KOS14986.1 - 0.0017 18.5 0.0 0.0055 16.8 0.0 1.8 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KOS14986.1 - 0.0029 17.9 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Miro PF08477.8 KOS14986.1 - 0.0074 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 KOS14986.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KOS14986.1 - 0.0077 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KOS14986.1 - 0.011 15.5 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 KOS14986.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KOS14986.1 - 0.016 15.1 0.1 0.094 12.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KOS14986.1 - 0.029 14.5 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KOS14986.1 - 0.048 13.1 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 KOS14986.1 - 0.049 12.5 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KOS14986.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 KOS14986.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4485 PF14846.1 KOS14986.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4485) NACHT PF05729.7 KOS14986.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 KOS14986.1 - 0.077 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 KOS14986.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 KOS14986.1 - 0.086 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 KOS14986.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin Acetyltransf_4 PF13420.1 KOS14986.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gtr1_RagA PF04670.7 KOS14986.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pkinase PF00069.20 KOS14987.1 - 9.1e-71 238.0 0.0 1.1e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14987.1 - 1.7e-32 112.4 0.0 2.8e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS14987.1 - 0.0022 16.9 0.0 0.93 8.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like GRAB PF10375.4 KOS14988.1 - 5.9e-08 32.0 0.5 8.1e-06 25.2 0.0 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain DUF4200 PF13863.1 KOS14988.1 - 0.055 13.4 50.2 0.041 13.8 5.9 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 KOS14988.1 - 0.13 12.5 0.3 0.13 12.5 0.2 5.5 2 1 2 4 4 3 0 Protein of unknown function (DUF904) DUF1796 PF08795.5 KOS14988.1 - 0.17 11.5 9.6 1.3 8.6 0.5 2.4 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Syntaxin-6_N PF09177.6 KOS14988.1 - 0.36 11.2 25.9 0.5 10.8 5.9 3.8 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF3584 PF12128.3 KOS14988.1 - 0.37 8.0 49.9 1.1 6.5 34.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 KOS14988.1 - 0.52 10.2 48.5 0.12 12.3 8.6 5.5 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KOS14988.1 - 0.6 9.6 60.6 2.6 7.5 19.6 4.0 1 1 3 4 4 4 0 IncA protein Reo_sigmaC PF04582.7 KOS14988.1 - 0.91 8.6 12.8 3.7 6.6 2.7 2.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KOS14988.1 - 5.6 6.7 17.2 3.7 7.3 1.7 3.7 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KOS14988.1 - 8.9 6.0 52.0 19 4.9 17.3 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KOS14988.1 - 9.7 4.7 42.1 0.77 8.3 10.6 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein LSM PF01423.17 KOS14989.1 - 5.2e-20 70.7 0.1 5.8e-20 70.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS14989.1 - 0.0003 20.6 0.0 0.00037 20.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Thioredoxin PF00085.15 KOS14990.1 - 6e-26 90.1 0.0 7.1e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS14990.1 - 9.7e-10 38.6 0.1 7.3e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS14990.1 - 5.2e-08 32.9 0.0 8.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KOS14990.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KOS14990.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KOS14990.1 - 0.0026 17.2 0.1 0.091 12.3 0.1 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KOS14990.1 - 0.0032 17.1 0.0 0.0085 15.7 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.9 KOS14990.1 - 0.009 16.2 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 KOS14990.1 - 0.0091 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain ABC_transp_aux PF09822.4 KOS14990.1 - 0.015 14.7 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Glutaredoxin PF00462.19 KOS14990.1 - 0.022 14.7 0.2 0.11 12.4 0.2 2.2 1 1 0 1 1 1 0 Glutaredoxin DSBA PF01323.15 KOS14990.1 - 0.099 12.1 0.2 1.4 8.4 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Pkinase PF00069.20 KOS14991.1 - 2.2e-70 236.8 0.1 3e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS14991.1 - 2.4e-42 144.8 0.0 3.5e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KOS14991.1 - 2.4e-28 97.9 0.0 4e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KOS14991.1 - 3.6e-06 26.1 0.0 9.8e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 KOS14991.1 - 0.031 13.8 0.2 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Ribosomal_L1 PF00687.16 KOS14992.1 - 5.8e-57 192.5 0.0 9.6e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Herpes_V23 PF01802.12 KOS14992.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein PBP1_TM PF14812.1 KOS14992.1 - 0.016 15.4 2.0 0.035 14.4 1.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S24e PF01282.14 KOS14993.1 - 6.1e-34 115.6 0.0 1e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e LSM PF01423.17 KOS14994.1 - 2e-18 65.6 0.2 2.4e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain Ras PF00071.17 KOS14995.1 - 1.1e-49 167.8 0.0 1.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS14995.1 - 1.4e-15 57.8 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS14995.1 - 6.1e-10 38.6 0.0 8.5e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS14995.1 - 9.1e-05 21.7 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS14995.1 - 0.0047 15.6 0.9 1.1 7.8 0.1 2.5 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 KOS14995.1 - 0.015 15.4 0.1 0.15 12.2 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 KOS14995.1 - 0.025 13.8 0.1 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KOS14995.1 - 0.07 13.2 0.1 0.19 11.8 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KOS14995.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 KOS14995.1 - 0.11 11.8 0.0 0.3 10.5 0.0 1.6 1 1 0 1 1 1 0 STAS domain GRIM-19 PF06212.7 KOS14996.1 - 5.1e-28 97.3 0.0 1.1e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 GRIM-19 protein Clathrin PF00637.15 KOS14996.1 - 3.5e-15 55.8 0.4 7.3e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KOS14996.1 - 0.065 13.1 0.2 0.57 10.1 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_2 PF13639.1 KOS14996.1 - 0.15 11.9 2.0 0.49 10.2 0.2 2.3 2 0 0 2 2 2 0 Ring finger domain NUDE_C PF04880.8 KOS14997.1 - 0.47 10.8 5.2 0.33 11.3 0.7 2.1 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region DUF1757 PF08560.5 KOS14998.1 - 0.022 14.4 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Gly-zipper_OmpA PF13436.1 KOS14998.1 - 0.11 12.1 0.5 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PTPS_related PF10131.4 KOS14999.1 - 0.0048 15.1 0.7 0.0059 14.8 0.5 1.0 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DIOX_N PF14226.1 KOS15000.1 - 2.9e-11 43.9 0.0 7.4e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KOS15000.1 - 7.2e-09 35.8 0.3 4e-08 33.4 0.0 2.4 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Trypsin_2 PF13365.1 KOS15001.1 - 1.9e-06 27.8 0.0 3.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF2414 PF10309.4 KOS15002.1 - 1.6e-10 40.4 0.0 2.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FAD_binding_3 PF01494.14 KOS15003.1 - 4.8e-26 91.6 0.0 7.6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KOS15003.1 - 5.2e-09 35.4 0.4 3.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS15003.1 - 8.2e-07 28.9 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS15003.1 - 0.00041 20.7 0.0 0.0031 17.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KOS15003.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KOS15003.1 - 0.0018 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KOS15003.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KOS15003.1 - 0.0025 16.3 0.0 0.004 15.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 KOS15003.1 - 0.0037 16.7 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KOS15003.1 - 0.0093 14.8 0.6 0.015 14.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KOS15003.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS15003.1 - 0.032 13.3 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.10 KOS15003.1 - 0.045 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KOS15003.1 - 0.05 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KOS15003.1 - 0.11 12.2 0.2 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KOS15003.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PI-PLC-X PF00388.14 KOS15004.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DPBB_1 PF03330.13 KOS15005.1 - 8.7e-12 44.8 0.3 2.3e-11 43.5 0.2 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KOS15005.1 - 0.00089 19.2 0.1 0.0017 18.3 0.0 1.5 2 0 0 2 2 2 1 Cerato-platanin Barwin PF00967.12 KOS15005.1 - 0.028 14.1 0.7 0.05 13.2 0.5 1.7 1 1 0 1 1 1 0 Barwin family ThiF PF00899.16 KOS15006.1 - 1.4e-35 122.0 0.2 2.7e-35 121.1 0.0 1.5 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 KOS15006.1 - 4.2e-25 87.1 0.7 7.7e-25 86.2 0.5 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 KOS15006.1 - 1.4e-18 66.4 0.0 2.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 KOS15006.1 - 1.4e-17 62.7 3.8 3.3e-17 61.6 2.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KOS15006.1 - 0.0022 17.5 0.5 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain UAE_UbL PF14732.1 KOS15006.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 KOS15006.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.3 KOS15006.1 - 0.17 11.7 2.2 0.41 10.5 1.5 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Peptidase_C13 PF01650.13 KOS15007.1 - 2e-46 158.3 0.2 2.6e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family DASH_Dad3 PF08656.5 KOS15008.1 - 6.5e-22 77.0 0.4 8.6e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Flu_M1_C PF08289.6 KOS15008.1 - 0.018 15.0 0.1 0.036 14.0 0.0 1.6 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DS PF01916.12 KOS15009.1 - 3.3e-131 436.8 0.0 4e-131 436.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Aldedh PF00171.17 KOS15010.1 - 8.1e-10 37.6 7.5 1.3e-08 33.6 5.2 2.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DPM2 PF07297.7 KOS15011.1 - 2.6e-24 85.2 1.2 3.1e-24 85.0 0.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KOS15011.1 - 1.6e-05 24.5 0.9 1.9e-05 24.2 0.6 1.1 1 0 0 1 1 1 1 PIG-P EI24 PF07264.6 KOS15011.1 - 0.0024 17.3 1.7 0.0027 17.1 1.2 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) OST3_OST6 PF04756.8 KOS15011.1 - 0.0085 15.6 0.3 0.01 15.4 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family GPI2 PF06432.6 KOS15011.1 - 0.062 12.6 0.1 0.073 12.3 0.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase COX14 PF14880.1 KOS15011.1 - 1.8 8.2 4.1 2.6 7.7 0.3 2.2 2 1 0 2 2 2 0 Cytochrome oxidase c assembly Steroid_dh PF02544.11 KOS15012.1 - 9.9e-39 132.4 3.1 9.9e-39 132.4 2.2 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KOS15012.1 - 6e-05 22.4 1.9 9.7e-05 21.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KOS15012.1 - 0.00041 20.4 0.9 0.00041 20.4 0.6 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase ubiquitin PF00240.18 KOS15012.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family ICMT PF04140.9 KOS15012.1 - 0.073 13.2 2.1 0.19 11.9 1.5 1.7 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family WD40 PF00400.27 KOS15013.1 - 1.2e-89 291.2 21.4 4.6e-13 48.4 0.0 9.1 9 0 0 9 9 9 9 WD domain, G-beta repeat eIF2A PF08662.6 KOS15013.1 - 8.5e-06 25.6 0.0 0.0017 18.1 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 KOS15013.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.1 KOS15013.1 - 0.00024 20.3 0.2 0.51 9.3 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KOS15013.1 - 0.00026 19.2 10.2 0.58 8.2 0.1 4.6 2 1 1 5 5 5 4 Nucleoporin Nup120/160 IKI3 PF04762.7 KOS15013.1 - 0.019 12.7 1.9 0.061 11.1 0.0 2.1 2 0 0 2 2 2 0 IKI3 family DUF3662 PF12401.3 KOS15013.1 - 0.035 14.2 0.5 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) Robl_LC7 PF03259.12 KOS15013.1 - 0.053 13.0 0.0 0.31 10.6 0.1 2.2 2 0 0 2 2 2 0 Roadblock/LC7 domain Nucleoporin_N PF08801.6 KOS15013.1 - 0.098 11.3 4.4 4.8 5.8 0.1 3.5 2 2 0 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 KOS15013.1 - 0.2 10.4 0.0 0.51 9.0 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region Methyltransf_11 PF08241.7 KOS15015.1 - 6.9e-14 52.1 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS15015.1 - 1.7e-11 44.0 0.0 2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS15015.1 - 1.9e-11 43.7 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS15015.1 - 3.3e-11 43.5 0.0 4.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS15015.1 - 1.6e-10 41.5 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS15015.1 - 9.1e-09 35.6 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS15015.1 - 1.9e-08 34.3 0.6 2.8e-08 33.7 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KOS15015.1 - 5.7e-08 32.1 0.0 7.6e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KOS15015.1 - 2.5e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 KOS15015.1 - 1e-05 24.9 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KOS15015.1 - 6e-05 22.6 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KOS15015.1 - 8.5e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KOS15015.1 - 0.0058 15.7 0.1 0.0072 15.4 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KOS15015.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KOS15015.1 - 0.032 13.4 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 KOS15015.1 - 0.049 13.1 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 KOS15015.1 - 0.051 12.6 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 KOS15015.1 - 0.063 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KOS15015.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 KOS15015.1 - 0.074 13.0 0.2 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 KOS15015.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB 2OG-FeII_Oxy_2 PF13532.1 KOS15017.1 - 2.1e-16 60.3 0.0 6.9e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KOS15017.1 - 3.3e-08 33.7 0.1 7e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop PF01798.13 KOS15018.1 - 7.1e-58 194.1 0.2 1.4e-57 193.2 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KOS15018.1 - 1.5e-26 91.9 0.0 2.6e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KOS15018.1 - 1.5e-15 57.0 0.3 1.5e-15 57.0 0.2 2.7 2 1 0 2 2 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KOS15018.1 - 0.043 13.4 40.2 0.083 12.5 27.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KOS15018.1 - 0.094 12.6 13.0 0.13 12.1 9.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 KOS15018.1 - 0.36 8.7 25.8 3.4 5.5 0.0 2.2 2 0 0 2 2 2 0 CDC45-like protein RR_TM4-6 PF06459.7 KOS15018.1 - 1.4 8.7 18.6 3.2 7.5 12.9 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 KOS15018.1 - 4 6.0 25.6 6.5 5.3 17.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 KOS15018.1 - 4.4 7.0 9.8 8.5 6.1 6.8 1.6 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 KOS15018.1 - 5.6 6.0 18.9 12 4.9 13.1 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Rtf2 PF04641.7 KOS15018.1 - 8.5 5.4 24.1 13 4.8 16.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MFS_1 PF07690.11 KOS15019.1 - 1.3e-41 142.5 48.9 1.2e-40 139.3 33.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS15019.1 - 1.5e-13 50.1 13.8 1.5e-13 50.1 9.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KOS15019.1 - 3.6e-05 22.1 17.8 7.2e-05 21.1 11.8 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KOS15021.1 - 2.9e-77 259.8 0.1 5e-77 259.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KOS15021.1 - 7.7e-70 234.6 0.0 1.3e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KOS15021.1 - 4.5e-14 52.4 0.0 1.3e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KOS15021.1 - 2e-10 40.5 0.0 5.1e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KOS15021.1 - 5e-08 33.7 2.4 9.7e-08 32.8 0.0 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KOS15021.1 - 3.6e-06 25.8 0.0 2.1e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 KOS15021.1 - 0.0006 18.7 0.0 0.0015 17.4 0.0 1.6 1 0 0 1 1 1 1 Condensation domain CTP_transf_1 PF01148.15 KOS15022.1 - 4.2e-73 246.2 18.1 6.5e-73 245.5 12.5 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family WBS_methylT PF12589.3 KOS15023.1 - 3.3e-19 69.1 8.4 6.2e-19 68.2 5.8 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KOS15023.1 - 1.9e-09 37.9 0.0 3.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS15023.1 - 4.4e-08 33.0 0.0 7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS15023.1 - 3.3e-06 27.3 0.0 6.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS15023.1 - 1.7e-05 24.4 0.0 3.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS15023.1 - 0.00018 22.0 0.1 0.00032 21.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS15023.1 - 0.00027 21.3 0.5 0.0016 18.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS15023.1 - 0.0084 16.1 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KOS15023.1 - 0.017 14.6 0.0 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 DNA methylase AdoMet_MTase PF07757.8 KOS15023.1 - 0.019 15.0 0.0 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 KOS15023.1 - 0.056 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) LSM PF01423.17 KOS15024.1 - 1.4e-15 56.6 0.6 1.7e-15 56.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 KOS15024.1 - 0.06 13.0 0.1 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 KOS15024.1 - 0.11 12.4 0.2 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 KOS15024.1 - 0.12 12.0 0.5 0.25 11.0 0.4 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain API5 PF05918.6 KOS15024.1 - 5.5 5.3 7.2 6.9 5.0 5.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pribosyltran_N PF13793.1 KOS15025.1 - 8.5e-44 148.0 0.2 6.2e-42 142.0 0.0 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KOS15025.1 - 3.8e-36 124.5 0.9 4.8e-32 111.1 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KOS15025.1 - 1.1e-11 44.5 0.9 5.1e-11 42.3 0.4 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KOS15025.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Aconitase PF00330.15 KOS15026.1 - 5.8e-153 509.7 0.0 2.8e-152 507.4 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KOS15026.1 - 1.4e-31 109.2 0.0 2.9e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 KOS15026.1 - 0.0022 17.8 2.7 0.029 14.2 0.8 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 DUF521 PF04412.8 KOS15026.1 - 0.082 11.4 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ribosomal_S21e PF01249.13 KOS15027.1 - 2e-32 110.9 0.0 2.2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF2040 PF09745.4 KOS15028.1 - 1.7e-36 124.8 21.9 1.7e-36 124.8 15.2 1.9 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Amidohydro_4 PF13147.1 KOS15028.1 - 0.0015 18.6 0.7 0.002 18.1 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase PALP PF00291.20 KOS15029.1 - 7.3e-51 173.2 0.0 8.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PUF PF00806.14 KOS15030.1 - 7.6e-58 188.8 5.6 3.1e-06 26.3 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ABC_tran PF00005.22 KOS15031.1 - 1.9e-43 148.0 0.0 3.1e-22 79.3 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS15031.1 - 1.7e-17 64.3 1.2 0.00055 19.9 0.0 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KOS15031.1 - 1.2e-11 44.2 3.9 0.24 10.6 0.0 4.7 5 0 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS15031.1 - 1.7e-09 37.0 0.3 0.00085 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS15031.1 - 1.6e-07 31.5 0.1 0.018 15.1 0.0 4.8 6 0 0 6 6 5 2 AAA domain AAA_10 PF12846.2 KOS15031.1 - 3.5e-06 26.6 3.8 0.022 14.2 0.0 4.2 4 1 0 4 4 3 2 AAA-like domain AAA_17 PF13207.1 KOS15031.1 - 3.7e-06 27.7 0.1 0.11 13.3 0.0 3.6 3 0 0 3 3 2 2 AAA domain CLASP_N PF12348.3 KOS15031.1 - 4.7e-06 26.1 0.0 0.046 13.0 0.1 2.7 1 1 1 2 2 2 2 CLASP N terminal Miro PF08477.8 KOS15031.1 - 1.1e-05 25.9 0.0 0.046 14.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KOS15031.1 - 1.3e-05 25.0 1.1 0.0053 16.6 0.0 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KOS15031.1 - 9.9e-05 22.0 0.0 0.25 10.9 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 KOS15031.1 - 0.00026 20.1 0.2 2.1 7.3 0.0 4.0 3 1 0 4 4 4 1 AAA ATPase domain HEAT_2 PF13646.1 KOS15031.1 - 0.00028 21.1 0.0 1.5 9.1 0.0 3.9 2 1 1 3 3 3 1 HEAT repeats DUF258 PF03193.11 KOS15031.1 - 0.00031 19.9 0.0 0.29 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KOS15031.1 - 0.00031 20.6 0.0 0.94 9.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KOS15031.1 - 0.00051 20.3 0.1 0.46 10.7 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KOS15031.1 - 0.00054 18.5 0.0 1.1 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KOS15031.1 - 0.00055 19.6 0.1 0.64 9.7 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KOS15031.1 - 0.00058 19.4 0.1 2.1 7.7 0.0 3.6 4 1 0 4 4 4 2 FtsK/SpoIIIE family AAA_33 PF13671.1 KOS15031.1 - 0.00058 19.7 0.0 0.99 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KOS15031.1 - 0.00081 19.5 0.1 3 8.0 0.0 4.9 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) Chromo PF00385.19 KOS15031.1 - 0.00084 18.9 0.3 0.0032 17.0 0.0 2.2 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_helicase PF00910.17 KOS15031.1 - 0.002 18.2 0.0 3.7 7.7 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KOS15031.1 - 0.0026 17.2 0.0 2.5 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 KOS15031.1 - 0.0029 16.4 0.2 0.51 9.0 0.0 2.8 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 KOS15031.1 - 0.0038 17.5 0.1 0.055 13.7 0.0 4.4 4 1 0 4 4 3 2 AAA domain DUF87 PF01935.12 KOS15031.1 - 0.0051 16.6 11.2 0.032 14.0 0.2 4.4 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_28 PF13521.1 KOS15031.1 - 0.0058 16.5 0.0 3.6 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KOS15031.1 - 0.0076 15.1 1.7 2.2 7.0 0.0 3.1 4 0 0 4 4 3 1 NB-ARC domain AAA_30 PF13604.1 KOS15031.1 - 0.0079 15.7 0.1 8.2 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KOS15031.1 - 0.01 15.7 6.2 0.25 11.2 1.0 4.0 3 1 0 3 3 3 0 AAA ATPase domain UME PF08064.8 KOS15031.1 - 0.014 15.3 0.8 0.049 13.5 0.2 2.2 2 0 0 2 2 2 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 KOS15031.1 - 0.023 15.0 0.0 0.95 9.8 0.0 2.9 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KOS15031.1 - 0.033 14.6 0.1 13 6.4 0.0 4.7 4 1 1 5 5 3 0 HEAT-like repeat AAA_14 PF13173.1 KOS15031.1 - 0.039 13.8 0.0 8.8 6.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 KOS15031.1 - 0.065 12.7 0.1 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KOS15031.1 - 0.079 12.7 0.1 0.74 9.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 KOS15031.1 - 0.089 12.6 1.0 2.2 8.0 0.0 2.9 3 0 0 3 3 2 0 Dynamin family G-alpha PF00503.15 KOS15031.1 - 0.13 10.8 6.8 1.2 7.7 0.0 2.8 3 0 0 3 3 2 0 G-protein alpha subunit Ofd1_CTDD PF10637.4 KOS15032.1 - 2.9e-88 295.4 0.0 2.9e-81 272.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KOS15032.1 - 3.7e-17 62.6 0.2 9.4e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KOS15032.1 - 0.005 16.4 0.6 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.7 KOS15032.1 - 1.9 8.1 8.5 3.6 7.2 5.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rot1 PF10681.4 KOS15033.1 - 2.6e-52 177.2 6.1 3.3e-52 176.9 4.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF1227 PF06777.6 KOS15034.1 - 9.3e-60 200.5 0.5 2e-59 199.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 KOS15034.1 - 3.6e-45 153.8 0.0 8.8e-45 152.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KOS15034.1 - 8.8e-43 145.7 0.1 7.7e-42 142.6 0.0 2.3 2 1 0 2 2 2 1 DEAD_2 ResIII PF04851.10 KOS15034.1 - 0.0015 18.4 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS15034.1 - 0.0023 17.4 0.2 1 8.8 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Peripla_BP_2 PF01497.13 KOS15034.1 - 0.0071 15.4 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein SNF2_N PF00176.18 KOS15034.1 - 0.026 13.3 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain YtxC PF08812.6 KOS15034.1 - 0.46 9.9 3.3 0.36 10.2 0.0 2.3 3 0 0 3 3 3 0 YtxC-like family Gly_transf_sug PF04488.10 KOS15035.1 - 3.8e-21 75.4 0.1 7e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KOS15035.1 - 0.0017 16.9 0.8 0.084 11.3 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KOS15035.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Sin_N PF04801.8 KOS15036.1 - 1.8e-28 99.5 0.0 2.2e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region DNA_primase_S PF01896.14 KOS15037.1 - 5e-48 162.5 0.0 8.4e-48 161.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF348 PF03990.9 KOS15037.1 - 0.043 13.3 0.2 0.098 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF348) WD40 PF00400.27 KOS15038.1 - 2.4e-40 134.9 3.6 1.7e-11 43.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KOS15038.1 - 8e-24 83.4 8.7 1.5e-23 82.5 6.0 1.5 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KOS15038.1 - 0.00015 21.5 0.0 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KOS15038.1 - 0.14 10.2 1.2 9.9 4.1 0.0 2.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 His_Phos_1 PF00300.17 KOS15039.1 - 0.0028 17.7 0.0 0.0036 17.3 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 14-3-3 PF00244.15 KOS15040.1 - 1.2e-117 391.1 6.6 1.3e-117 390.9 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF342 PF03961.8 KOS15040.1 - 0.22 9.9 2.4 0.2 10.0 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) tRNA-synt_1b PF00579.20 KOS15041.1 - 3e-72 243.2 0.0 4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_L16 PF00252.13 KOS15042.1 - 2.4e-32 111.4 0.1 3.1e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RRN3 PF05327.6 KOS15043.1 - 1.2e-149 499.0 0.0 8.6e-149 496.2 0.0 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Pex14_N PF04695.8 KOS15043.1 - 0.055 13.5 0.1 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.8 KOS15044.1 - 2.6e-51 173.7 0.0 4.4e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KOS15044.1 - 1.1e-12 47.2 0.0 1.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS15044.1 - 1.6e-11 43.6 0.0 2.6e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS15044.1 - 1.1e-10 40.6 0.0 2.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Pex2_Pex12 PF04757.9 KOS15044.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Ribosomal_S10 PF00338.17 KOS15045.1 - 2.2e-29 101.1 0.3 2.6e-29 100.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UDPG_MGDP_dh_N PF03721.9 KOS15046.1 - 1e-55 187.9 0.1 2.5e-55 186.7 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KOS15046.1 - 7.9e-32 109.5 0.1 3.4e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KOS15046.1 - 7.3e-31 106.2 0.0 1.5e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 KOS15046.1 - 0.0021 17.7 0.1 0.06 13.0 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KOS15046.1 - 0.0077 16.6 0.0 3.9 7.9 0.0 2.8 2 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KOS15046.1 - 0.028 13.3 0.1 0.068 12.1 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase ALG3 PF05208.8 KOS15047.1 - 9.8e-114 380.4 12.8 9.8e-114 380.4 8.9 1.4 2 0 0 2 2 2 1 ALG3 protein DUF3146 PF11344.3 KOS15047.1 - 0.032 13.6 0.5 0.067 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) SBDS_C PF09377.5 KOS15048.1 - 9.4e-44 148.1 0.7 1.8e-43 147.2 0.5 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KOS15048.1 - 2.4e-32 110.5 0.6 4.3e-32 109.7 0.5 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNARE_assoc PF09335.6 KOS15049.1 - 1.3e-06 28.5 1.2 2.5e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein UPF0104 PF03706.8 KOS15049.1 - 0.0011 18.3 3.9 0.4 9.9 0.4 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0104) Tetraspannin PF00335.15 KOS15049.1 - 0.27 10.4 1.4 0.5 9.6 1.0 1.3 1 1 0 1 1 1 0 Tetraspanin family ABC_tran PF00005.22 KOS15050.1 - 4.2e-46 156.6 0.1 5.4e-23 81.7 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KOS15050.1 - 1.9e-23 82.0 3.7 1.9e-23 82.0 2.5 3.8 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 KOS15050.1 - 8e-17 62.1 5.0 2.4e-06 27.7 0.0 4.5 4 1 1 5 5 4 3 AAA domain SMC_N PF02463.14 KOS15050.1 - 8.5e-09 34.9 0.1 0.013 14.7 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KOS15050.1 - 1.6e-08 34.7 0.3 0.0064 16.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS15050.1 - 1.1e-07 31.2 0.0 0.0042 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS15050.1 - 2.4e-07 31.6 0.4 0.092 13.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 KOS15050.1 - 5e-07 29.6 0.0 0.023 14.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 KOS15050.1 - 9.6e-07 28.8 0.0 0.015 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KOS15050.1 - 2.3e-06 26.9 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KOS15050.1 - 4.4e-06 27.1 0.0 0.16 12.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 KOS15050.1 - 3.7e-05 23.4 0.0 0.092 12.4 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KOS15050.1 - 3.8e-05 23.4 0.1 0.34 10.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 KOS15050.1 - 3.9e-05 22.8 0.2 0.14 11.1 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 KOS15050.1 - 5.7e-05 22.1 0.0 0.036 12.9 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 KOS15050.1 - 0.00016 21.1 0.3 0.72 9.2 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 KOS15050.1 - 0.00019 21.7 0.5 3.4 7.9 0.0 4.1 5 0 0 5 5 3 1 AAA domain AAA_33 PF13671.1 KOS15050.1 - 0.00022 21.1 3.4 0.52 10.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain ArgK PF03308.11 KOS15050.1 - 0.00029 19.7 0.0 0.38 9.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 KOS15050.1 - 0.00041 20.2 0.1 0.15 11.9 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KOS15050.1 - 0.00071 19.9 8.1 0.76 10.0 0.0 4.6 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 KOS15050.1 - 0.0008 19.5 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Cuticle_3 PF11018.3 KOS15050.1 - 0.0023 18.1 0.1 0.0049 17.0 0.1 1.5 1 0 0 1 1 1 1 Pupal cuticle protein C1 AAA_14 PF13173.1 KOS15050.1 - 0.0034 17.2 0.0 5 7.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 KOS15050.1 - 0.0034 17.5 0.0 1.4 9.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS15050.1 - 0.0041 16.5 0.1 3.7 6.9 0.0 3.0 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KOS15050.1 - 0.005 16.6 4.4 1.3 8.8 0.1 4.0 4 0 0 4 4 4 1 Dynamin family cobW PF02492.14 KOS15050.1 - 0.0063 15.9 0.0 2.1 7.7 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KOS15050.1 - 0.0066 16.4 7.8 0.49 10.3 0.5 3.6 3 2 0 3 3 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KOS15050.1 - 0.0073 15.8 0.0 0.66 9.4 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 KOS15050.1 - 0.011 14.7 0.0 0.035 12.9 0.0 1.9 2 0 0 2 2 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 KOS15050.1 - 0.012 15.3 0.3 3.4 7.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KOS15050.1 - 0.024 14.3 0.6 9.7 5.8 0.0 3.2 3 1 0 3 3 2 0 Archaeal ATPase DUF87 PF01935.12 KOS15050.1 - 0.029 14.1 0.0 0.029 14.1 0.0 3.6 5 0 0 5 5 4 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 KOS15050.1 - 0.045 13.4 0.0 8.8 6.0 0.0 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KOS15050.1 - 0.13 11.7 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.24 KOS15051.1 - 2.6e-43 147.4 0.7 7.5e-43 145.9 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15051.1 - 7.1e-28 96.2 0.3 2.2e-27 94.6 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KOS15051.1 - 1.3e-05 24.8 0.3 3.3e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KOS15051.1 - 8.6e-05 22.4 0.0 0.0002 21.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KOS15051.1 - 0.0034 16.9 0.1 0.017 14.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS15051.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 KOS15051.1 - 0.049 12.7 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Fanconi_A PF03511.9 KOS15051.1 - 0.06 13.1 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein Flavi_DEAD PF07652.9 KOS15051.1 - 0.077 12.7 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain CMS1 PF14617.1 KOS15051.1 - 0.089 11.8 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Na_H_Exchanger PF00999.16 KOS15052.1 - 1.5e-66 224.5 36.9 1.9e-66 224.1 25.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Actin PF00022.14 KOS15053.1 - 7.3e-42 143.1 0.1 6e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 Actin PMT PF02366.13 KOS15054.1 - 1.4e-74 250.6 21.3 1.4e-74 250.6 14.8 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS15054.1 - 5.1e-19 68.5 0.7 5.8e-18 65.0 0.5 2.1 1 1 0 1 1 1 1 MIR domain UPF0121 PF03661.8 KOS15055.1 - 6.1e-23 81.2 4.1 7.9e-23 80.9 2.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CDC37_N PF03234.9 KOS15056.1 - 8.6e-47 159.7 9.6 8.6e-47 159.7 6.6 1.7 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KOS15056.1 - 3.9e-25 88.3 6.3 7.7e-22 77.5 0.0 2.6 3 0 0 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KOS15056.1 - 4e-18 65.1 1.3 1.2e-17 63.6 0.0 2.5 3 0 0 3 3 3 1 Cdc37 C terminal domain Peptidase_S49 PF01343.13 KOS15057.1 - 1e-50 171.4 1.0 2e-26 92.6 1.0 3.3 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 KOS15057.1 - 3.9e-08 33.1 1.0 5.9e-06 26.0 0.2 2.6 2 1 0 2 2 2 2 Clp protease SDH_sah PF01972.11 KOS15057.1 - 0.0001 21.2 0.1 0.00023 20.0 0.1 1.5 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Ligase_CoA PF00549.14 KOS15057.1 - 0.064 12.8 0.3 0.48 10.0 0.1 2.4 1 1 1 2 2 2 0 CoA-ligase Atg14 PF10186.4 KOS15058.1 - 0.026 13.4 13.3 0.85 8.5 9.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2353 PF09789.4 KOS15058.1 - 0.075 12.2 8.8 0.13 11.5 6.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.4 KOS15058.1 - 0.21 11.4 12.6 0.4 10.5 8.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 KOS15058.1 - 0.56 10.0 14.5 1.1 9.1 10.0 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF4407 PF14362.1 KOS15058.1 - 1.5 7.7 11.9 2.7 6.8 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 KOS15058.1 - 1.6 9.4 7.7 3.2 8.5 5.3 1.4 1 0 0 1 1 1 0 Occludin homology domain DUF342 PF03961.8 KOS15058.1 - 3.3 6.0 4.7 4.7 5.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KOS15058.1 - 3.8 5.2 6.4 5.3 4.7 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KOS15058.1 - 5.1 6.6 20.4 9.2 5.8 14.1 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KOS15058.1 - 7.1 5.5 13.8 11 4.8 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KOS15058.1 - 8.5 6.2 13.8 0.39 10.5 3.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KOS15058.1 - 9.8 6.5 8.9 24 5.3 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SIR2 PF02146.12 KOS15059.1 - 8e-58 195.0 0.0 1.4e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KOS15059.1 - 1.4e-07 31.1 0.1 2.9e-06 26.9 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF592) CutC PF03932.9 KOS15059.1 - 0.00053 19.2 0.0 0.0024 17.1 0.0 2.0 2 0 0 2 2 2 1 CutC family TPP_enzyme_M PF00205.17 KOS15059.1 - 0.042 13.5 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RRN3 PF05327.6 KOS15059.1 - 1.6 6.7 4.0 2.6 6.0 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP-synt_C PF00137.16 KOS15060.1 - 2.3e-28 97.8 32.1 2.9e-17 62.3 5.9 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 KOS15060.1 - 0.57 9.8 5.0 0.69 9.5 2.1 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PX PF00787.19 KOS15061.1 - 1.3e-22 79.6 0.2 2.1e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 PX domain XPG_N PF00752.12 KOS15062.1 - 2.5e-34 117.5 0.0 5.6e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS15062.1 - 3.4e-30 103.9 0.0 6.9e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KOS15062.1 - 2.4e-08 34.1 0.1 6.9e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KOS15062.1 - 0.027 14.6 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KOS15062.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda SKN1 PF03935.10 KOS15063.1 - 2.1e-171 570.5 4.0 2.6e-171 570.2 2.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3471 PF11954.3 KOS15063.1 - 0.056 13.2 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) zf-C2H2_4 PF13894.1 KOS15064.1 - 3.7e-12 45.6 18.2 0.00023 21.2 0.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS15064.1 - 4.3e-11 42.4 25.0 3.8e-06 26.9 0.6 4.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS15064.1 - 3.3e-07 30.2 14.4 0.064 13.5 0.2 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KOS15064.1 - 0.022 14.8 5.6 1.2 9.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KOS15064.1 - 0.035 13.7 14.3 0.15 11.7 0.7 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KOS15064.1 - 0.15 12.2 1.9 6.3 6.9 0.0 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 KOS15064.1 - 0.16 11.5 1.4 6.9 6.3 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KOS15064.1 - 0.2 11.3 1.3 8.1 6.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KOS15064.1 - 1.3 9.0 6.1 4 7.4 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 KOS15065.1 - 1.4e-48 165.4 0.0 3e-48 164.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family TPPII PF12580.3 KOS15065.1 - 3.4e-44 150.5 0.0 5.3e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Sld5 PF05916.6 KOS15067.1 - 7.9e-09 35.7 2.3 1.6e-08 34.8 1.6 1.5 1 0 0 1 1 1 1 GINS complex protein DUF1818 PF08848.6 KOS15067.1 - 0.059 13.4 0.3 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) Fcf1 PF04900.7 KOS15068.1 - 1.1e-20 73.6 0.1 2.6e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Fcf1 Presenilin PF01080.12 KOS15068.1 - 0.1 11.4 0.2 0.18 10.5 0.1 1.4 1 0 0 1 1 1 0 Presenilin DUF1469 PF07332.6 KOS15069.1 - 0.01 15.5 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Gtr1_RagA PF04670.7 KOS15070.1 - 3.8e-40 137.4 0.2 1.5e-37 128.9 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS15070.1 - 1.5e-05 25.4 0.0 3.8e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS15070.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KOS15070.1 - 0.001 18.3 0.0 0.16 11.2 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.8 KOS15070.1 - 0.0023 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KOS15070.1 - 0.0024 17.7 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS15070.1 - 0.0041 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KOS15070.1 - 0.0063 15.9 0.0 0.02 14.3 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 KOS15070.1 - 0.0097 15.3 0.0 0.052 12.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 KOS15070.1 - 0.0097 15.6 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 KOS15070.1 - 0.034 14.4 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF1647 PF07801.6 KOS15070.1 - 0.085 12.3 0.5 0.25 10.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) zf-C4H2 PF10146.4 KOS15070.1 - 0.2 11.6 0.4 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein LisH PF08513.6 KOS15071.1 - 0.0048 16.6 0.2 0.0082 15.8 0.1 1.4 1 0 0 1 1 1 1 LisH DUF1424 PF07232.6 KOS15071.1 - 0.0057 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative rep protein (DUF1424) Nup160 PF11715.3 KOS15072.1 - 3e-42 144.4 0.0 6.8e-42 143.3 0.0 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nol1_Nop2_Fmu PF01189.12 KOS15073.1 - 2e-16 60.2 0.1 1.4e-10 41.0 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family BcrAD_BadFG PF01869.15 KOS15073.1 - 2.6e-15 56.4 0.0 4.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FtsJ PF01728.14 KOS15073.1 - 1.4e-05 25.2 0.0 3.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KOS15073.1 - 9.7e-05 22.3 1.1 0.00028 20.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS15073.1 - 0.0086 15.4 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain IBN_N PF03810.14 KOS15074.1 - 1.6e-08 34.2 1.3 2.7e-07 30.4 0.4 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KOS15074.1 - 0.057 13.3 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Exportin 1-like protein Vps52 PF04129.7 KOS15075.1 - 1.9e-34 119.0 0.2 3.3e-31 108.4 0.1 3.1 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 KOS15075.1 - 0.0004 18.6 1.8 0.0011 17.2 0.3 2.1 3 0 0 3 3 3 1 Exocyst complex component Sec3 CENP-Q PF13094.1 KOS15075.1 - 0.0029 17.6 4.7 0.0061 16.6 3.3 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 KOS15075.1 - 0.0046 16.4 1.8 0.0087 15.5 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 KOS15075.1 - 0.0052 16.6 4.2 0.0052 16.6 2.9 1.9 3 0 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KOS15075.1 - 0.0056 16.0 16.3 0.016 14.5 11.3 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Spc7 PF08317.6 KOS15075.1 - 0.015 14.0 3.7 0.024 13.2 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KOS15075.1 - 0.019 15.1 1.6 0.027 14.6 0.3 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 KOS15075.1 - 0.1 12.8 3.2 0.2 11.9 1.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KOS15075.1 - 0.15 11.5 6.2 0.25 10.7 2.9 2.1 2 0 0 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KOS15075.1 - 0.16 11.8 10.8 0.11 12.2 2.8 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 KOS15075.1 - 0.32 10.7 5.6 0.89 9.3 3.2 2.1 2 0 0 2 2 2 0 Laminin Domain II Muted PF14942.1 KOS15075.1 - 0.47 10.3 2.7 1.4 8.7 1.9 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein GrpE PF01025.14 KOS15075.1 - 0.71 9.3 3.3 63 3.0 0.0 2.7 2 1 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.17 KOS15075.1 - 1.4 8.9 5.8 0.75 9.8 1.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Brix PF04427.13 KOS15076.1 - 7.2e-43 146.4 0.0 1.2e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain Daxx PF03344.10 KOS15076.1 - 0.012 14.1 14.8 0.017 13.6 10.3 1.3 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 KOS15076.1 - 0.018 14.8 19.3 0.026 14.2 13.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPDY PF03771.11 KOS15076.1 - 0.027 13.9 0.2 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Nop14 PF04147.7 KOS15076.1 - 0.053 11.4 16.5 0.071 11.0 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KOS15076.1 - 0.092 11.7 6.4 0.15 11.0 4.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIA PF03153.8 KOS15076.1 - 0.4 10.5 15.0 0.62 9.8 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KOS15076.1 - 1.6 7.9 6.9 2.3 7.3 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 KOS15076.1 - 6.4 4.7 6.7 10 4.0 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2526 PF10735.4 KOS15077.1 - 0.076 13.0 0.2 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) TRAM_LAG1_CLN8 PF03798.11 KOS15078.1 - 0.0017 17.9 20.7 0.0028 17.2 14.4 1.4 1 0 0 1 1 1 1 TLC domain VPS9 PF02204.13 KOS15079.1 - 2.9e-29 101.1 0.0 5.1e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KOS15079.1 - 2.3e-11 42.9 0.1 4.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 KOS15079.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif Dynamin_M PF01031.15 KOS15080.1 - 2.2e-111 371.4 0.0 3.9e-111 370.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KOS15080.1 - 1.8e-55 187.3 0.0 3.5e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KOS15080.1 - 6e-27 93.3 2.9 1e-26 92.6 1.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KOS15080.1 - 0.0028 17.5 0.0 0.0089 15.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS15080.1 - 0.023 15.1 0.1 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 KOS15080.1 - 0.11 11.5 0.3 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 AIG1 family P16-Arc PF04699.9 KOS15081.1 - 2.3e-43 147.8 0.0 2.5e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PPR_3 PF13812.1 KOS15082.1 - 2.2e-21 74.2 30.8 0.04 14.2 0.0 13.2 13 1 1 14 14 14 7 Pentatricopeptide repeat domain PPR_2 PF13041.1 KOS15082.1 - 4.1e-20 71.5 0.0 1.8e-06 27.8 0.0 7.2 6 2 1 7 7 7 4 PPR repeat family PPR PF01535.15 KOS15082.1 - 2.4e-16 58.4 3.2 0.025 14.5 0.0 10.2 13 0 0 13 13 13 4 PPR repeat PPR_1 PF12854.2 KOS15082.1 - 4.2e-06 26.1 0.0 6.5 6.3 0.0 6.4 6 0 0 6 6 6 2 PPR repeat Met_asp_mut_E PF06368.6 KOS15082.1 - 0.084 11.0 0.0 0.17 10.0 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) TPR_19 PF14559.1 KOS15082.1 - 0.099 12.9 19.9 2.8 8.3 0.1 6.6 8 1 1 9 9 9 0 Tetratricopeptide repeat SMK-1 PF04802.10 KOS15083.1 - 1.1e-52 178.3 1.4 2e-52 177.5 1.0 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 OHCU_decarbox PF09349.5 KOS15084.1 - 1.9e-31 109.5 0.1 2.1e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase L51_S25_CI-B8 PF05047.11 KOS15085.1 - 0.00017 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TPR_MLP1_2 PF07926.7 KOS15086.1 - 3.3e-07 30.1 22.2 3.3e-07 30.1 15.4 14.3 8 3 4 14 14 14 5 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 KOS15086.1 - 8.7e-07 28.7 7.7 8.7e-07 28.7 5.3 13.7 8 5 8 16 16 16 8 Laminin Domain II AAA_23 PF13476.1 KOS15087.1 - 2.2e-23 83.6 5.0 2.2e-23 83.6 3.4 4.9 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.14 KOS15087.1 - 1.3e-17 63.7 0.0 3.4e-08 33.0 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS15087.1 - 1.1e-10 41.9 0.0 0.00022 21.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KOS15087.1 - 1.6e-09 37.5 0.3 3.1e-08 33.4 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KOS15087.1 - 1.8e-06 27.2 0.0 0.0013 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.1 KOS15087.1 - 4.3e-06 25.4 67.4 0.00031 19.3 0.0 6.5 3 1 2 6 6 6 3 AAA domain AAA_29 PF13555.1 KOS15087.1 - 0.0035 16.8 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1829 PF08862.5 KOS15087.1 - 0.024 14.8 0.0 0.58 10.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF1829 ABC_tran PF00005.22 KOS15087.1 - 0.026 14.8 0.0 0.026 14.8 0.0 6.2 3 1 1 5 5 5 0 ABC transporter DLIC PF05783.6 KOS15088.1 - 1.7e-24 86.3 0.0 6.5e-13 48.1 0.0 3.8 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 KOS15088.1 - 5.8e-05 23.1 0.7 0.00028 20.9 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 KOS15088.1 - 7.9e-05 23.1 0.0 0.00043 20.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KOS15088.1 - 0.00016 21.8 0.2 0.0017 18.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KOS15088.1 - 0.00023 20.6 0.0 0.00066 19.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS15088.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain NACHT PF05729.7 KOS15088.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KOS15088.1 - 0.0039 17.4 0.0 0.0077 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 KOS15088.1 - 0.0043 17.8 0.0 0.017 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS15088.1 - 0.0062 16.2 0.7 0.048 13.4 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KOS15088.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KOS15088.1 - 0.0067 16.3 0.3 0.022 14.6 0.1 2.1 2 1 1 3 3 2 1 AAA domain AAA_28 PF13521.1 KOS15088.1 - 0.0079 16.1 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KOS15088.1 - 0.0089 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KOS15088.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS15088.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KOS15088.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KOS15088.1 - 0.027 14.1 0.1 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KOS15088.1 - 0.048 13.4 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KOS15088.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 KOS15088.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.24 KOS15088.1 - 0.074 13.2 0.2 0.15 12.2 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KOS15088.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KOS15088.1 - 0.077 12.5 0.5 0.19 11.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.12 KOS15088.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KOS15088.1 - 0.13 11.3 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 KOS15088.1 - 0.14 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF912 PF06024.7 KOS15089.1 - 0.028 14.4 0.2 2 8.5 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CAML PF14963.1 KOS15090.1 - 0.013 14.9 0.9 0.017 14.4 0.0 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand SCP2 PF02036.12 KOS15091.1 - 0.00057 20.1 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family DUF1077 PF06417.7 KOS15092.1 - 3e-42 142.9 6.3 3.9e-42 142.5 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF106 PF01956.11 KOS15092.1 - 0.0092 15.5 4.2 0.011 15.2 2.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Ribosomal_L7Ae PF01248.21 KOS15093.1 - 2.1e-23 81.6 0.1 3.8e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ETF_QO PF05187.8 KOS15093.1 - 0.023 14.6 0.9 0.034 14.1 0.6 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF2722 PF10846.3 KOS15093.1 - 0.13 11.2 2.4 0.17 10.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM176 PF14851.1 KOS15093.1 - 0.91 9.1 3.1 1.6 8.4 2.1 1.4 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.3 KOS15093.1 - 1 8.0 8.1 1.3 7.7 5.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rota_VP2 PF05087.7 KOS15093.1 - 1.7 6.4 7.2 2 6.1 5.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF3824 PF12868.2 KOS15093.1 - 5.1 8.0 5.8 1.1 10.2 1.2 1.8 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Cullin_binding PF03556.10 KOS15094.1 - 5.8e-31 107.0 0.1 1.1e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KOS15094.1 - 2e-12 46.4 1.5 4.1e-12 45.4 0.4 1.9 2 0 0 2 2 2 1 UBA-like domain 3-HAO PF06052.7 KOS15095.1 - 4.1e-41 139.9 0.1 5.2e-40 136.3 0.1 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KOS15095.1 - 0.0054 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KOS15095.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Cupin PFU PF09070.6 KOS15096.1 - 1.1e-34 118.8 0.0 1.8e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KOS15096.1 - 1.5e-21 75.3 29.8 1.5e-06 27.8 2.4 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat PUL PF08324.6 KOS15096.1 - 1.6e-17 63.2 0.0 2.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 KOS15096.1 - 0.0019 17.9 0.0 3.6 7.3 0.0 3.7 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KOS15096.1 - 0.12 12.6 2.1 6.3 7.2 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Glyco_transf_41 PF13844.1 KOS15097.1 - 2.4e-101 339.0 0.2 1.9e-46 158.0 0.0 4.4 4 0 0 4 4 4 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KOS15097.1 - 9.5e-20 70.0 1.5 1.1e-07 31.3 0.1 4.3 3 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KOS15097.1 - 4.5e-17 60.8 0.7 2e-05 23.9 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15097.1 - 3.1e-13 48.5 2.0 0.0039 17.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15097.1 - 7.3e-13 48.2 0.1 1.8e-08 34.1 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15097.1 - 8e-13 47.5 0.9 0.0038 17.3 0.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KOS15097.1 - 1.9e-10 40.3 9.5 0.012 15.4 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15097.1 - 2.2e-10 40.2 8.3 0.00026 21.3 0.1 5.6 4 2 2 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15097.1 - 6.5e-10 39.4 5.2 0.012 16.2 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS15097.1 - 3.5e-09 35.7 0.0 0.091 12.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15097.1 - 4.6e-09 35.4 0.0 0.00077 19.0 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15097.1 - 6.6e-07 29.0 5.3 0.0016 18.2 0.3 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KOS15097.1 - 9.8e-06 25.9 0.2 0.00041 20.6 0.1 2.8 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 KOS15097.1 - 1.4e-05 25.1 0.1 0.82 10.2 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15097.1 - 5.4e-05 23.4 0.1 0.028 14.7 0.0 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_5 PF12688.2 KOS15097.1 - 0.00089 19.2 0.0 0.0073 16.3 0.0 2.5 3 0 0 3 3 3 1 Tetratrico peptide repeat Apc3 PF12895.2 KOS15097.1 - 0.1 12.7 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Aminotran_3 PF00202.16 KOS15098.1 - 1.2e-106 356.4 0.0 1.6e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KOS15098.1 - 7.9e-05 21.9 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KOS15098.1 - 0.0006 18.8 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KOS15098.1 - 0.078 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V XPG_N PF00752.12 KOS15099.1 - 2.7e-27 94.9 0.0 6.3e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KOS15099.1 - 1.3e-26 92.4 0.1 2.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KOS15099.1 - 0.00027 20.5 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KOS15099.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Trypsin PF00089.21 KOS15100.1 - 0.11 12.0 5.7 14 5.1 0.2 4.1 1 1 2 3 3 3 0 Trypsin IBR PF01485.16 KOS15101.1 - 1.9e-20 72.4 39.2 6.1e-11 42.0 1.9 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 KOS15101.1 - 6.2e-06 25.7 2.8 6.2e-06 25.7 1.9 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15101.1 - 0.0001 22.2 4.1 0.0001 22.2 2.8 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS15101.1 - 0.00016 21.4 4.0 0.00016 21.4 2.8 3.8 2 1 1 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.1 KOS15101.1 - 0.0067 16.1 15.2 0.036 13.7 0.9 3.8 3 0 0 3 3 3 2 RING-type zinc-finger DUF1488 PF07369.6 KOS15101.1 - 0.067 13.0 0.4 4.9 7.0 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1488) Arylsulfotran_2 PF14269.1 KOS15102.1 - 8.5e-43 146.6 2.1 8.5e-43 146.6 1.4 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KOS15102.1 - 3.2e-14 52.3 1.9 1.2e-13 50.4 1.3 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BSD PF03909.12 KOS15103.1 - 2.3e-18 65.6 0.0 8.5e-14 51.0 0.1 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KOS15103.1 - 8.2e-10 38.2 0.0 5.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Hid1 PF12722.2 KOS15104.1 - 1e-98 331.2 0.0 1.4e-98 330.7 0.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KOS15104.1 - 1.4e-30 106.0 0.0 7.6e-30 103.6 0.0 1.8 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein zf-DBF PF07535.7 KOS15104.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.7 1 0 0 1 1 1 0 DBF zinc finger NOA36 PF06524.7 KOS15104.1 - 0.87 8.7 5.7 1.4 8.1 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein NAC PF01849.13 KOS15105.1 - 1e-15 56.9 0.6 2.1e-13 49.5 0.4 2.5 1 1 0 1 1 1 1 NAC domain UBA PF00627.26 KOS15105.1 - 5.7e-05 22.8 0.1 0.00013 21.6 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KOS15105.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain dsrm PF00035.20 KOS15106.1 - 1.7e-08 34.8 0.0 2.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KOS15106.1 - 3.7e-05 23.6 0.0 7.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KOS15106.1 - 4.1e-05 23.9 0.0 0.0001 22.7 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain NADH_B2 PF14813.1 KOS15107.1 - 0.00049 19.7 0.6 0.00053 19.6 0.4 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Rad51 PF08423.6 KOS15108.1 - 9.5e-08 31.2 0.8 7.9e-07 28.2 0.4 2.1 1 1 1 2 2 2 1 Rad51 AAA_25 PF13481.1 KOS15108.1 - 1.5e-05 24.4 0.4 8e-05 22.1 0.3 2.0 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 KOS15108.1 - 0.00035 19.7 0.4 0.0008 18.5 0.1 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 KOS15108.1 - 0.00096 18.3 0.1 0.0024 17.0 0.1 1.7 1 0 0 1 1 1 1 KaiC Sep15_SelM PF08806.6 KOS15108.1 - 0.097 12.4 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Sep15/SelM redox domain PRCC PF10253.4 KOS15111.1 - 4e-16 60.2 6.2 4e-16 60.2 4.3 2.3 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting zf-CCHC PF00098.18 KOS15112.1 - 6.5e-15 54.2 20.3 0.00086 19.1 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KOS15112.1 - 6.1e-07 28.8 16.4 0.00037 19.9 0.4 4.1 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 KOS15112.1 - 2e-06 27.3 20.1 0.13 11.9 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.1 KOS15112.1 - 0.0065 16.1 13.3 1.2 8.8 0.5 3.7 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.1 KOS15112.1 - 0.047 13.1 0.9 0.047 13.1 0.6 3.6 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger DUF2732 PF10809.3 KOS15112.1 - 0.17 11.4 2.4 0.49 9.9 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) mono-CXXC PF15626.1 KOS15112.1 - 0.31 10.9 6.0 2.8 7.9 0.5 3.6 2 1 0 2 2 2 0 single CXXC unit PIG-F PF06699.6 KOS15113.1 - 7.2e-22 78.2 8.8 1.1e-21 77.6 6.1 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F MOR2-PAG1_N PF14222.1 KOS15114.1 - 4.5e-93 312.8 0.0 7.5e-93 312.0 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KOS15114.1 - 3.8e-29 102.2 3.8 3.8e-29 102.2 2.6 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KOS15114.1 - 3.6e-11 41.4 0.2 7.5e-07 27.1 0.0 2.1 2 0 0 2 2 2 2 Cell morphogenesis central region Nup88 PF10168.4 KOS15115.1 - 4.7e-26 90.8 0.0 3.9e-13 48.1 0.1 2.2 2 0 0 2 2 2 2 Nuclear pore component DUF948 PF06103.6 KOS15115.1 - 0.061 13.1 3.8 0.78 9.6 0.3 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DNA_pol_E_B PF04042.11 KOS15116.1 - 5.6e-32 110.6 0.3 7.7e-32 110.2 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 KOS15116.1 - 1.1e-12 48.0 0.0 2.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Pex2_Pex12 PF04757.9 KOS15117.1 - 2.8e-36 125.0 8.1 4.4e-36 124.4 5.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region DUF2404 PF10296.4 KOS15118.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Ribosomal_S18 PF01084.15 KOS15119.1 - 5.2e-19 67.8 0.1 1e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Response_reg PF00072.19 KOS15120.1 - 7.9e-05 22.6 0.2 0.00017 21.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KOS15120.1 - 0.0047 17.2 0.0 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain CALCOCO1 PF07888.6 KOS15121.1 - 5.6e-06 24.9 12.9 1.1e-05 23.9 8.9 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Macoilin PF09726.4 KOS15121.1 - 0.082 11.1 13.1 0.16 10.2 9.1 1.4 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 KOS15121.1 - 0.37 10.6 15.7 0.81 9.5 10.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sugarporin_N PF11471.3 KOS15121.1 - 0.62 9.7 8.5 0.089 12.4 0.5 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension V_ATPase_I PF01496.14 KOS15121.1 - 4.3 5.0 2.9 7.3 4.3 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KOS15121.1 - 4.8 5.7 13.0 0.42 9.2 5.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Rhodanese PF00581.15 KOS15122.1 - 1.2e-17 64.3 0.0 1.7e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain BCDHK_Adom3 PF10436.4 KOS15123.1 - 1.2e-26 93.1 4.4 1.7e-26 92.7 3.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KOS15123.1 - 8e-06 25.5 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ku_PK_bind PF08785.6 KOS15123.1 - 0.082 12.8 0.2 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like DUF1935 PF09149.5 KOS15124.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) SIR2 PF02146.12 KOS15125.1 - 2e-55 187.2 0.0 2.8e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Voldacs PF03517.8 KOS15125.1 - 0.065 13.0 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Methyltransf_31 PF13847.1 KOS15126.1 - 8.8e-12 44.8 0.0 1.5e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KOS15126.1 - 2.7e-10 39.8 0.1 3.7e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KOS15126.1 - 2.7e-09 37.5 0.1 5.4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KOS15126.1 - 5.8e-09 35.3 0.0 7.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 KOS15126.1 - 1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS15126.1 - 7.3e-08 32.8 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS15126.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KOS15126.1 - 1.2e-05 24.2 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KOS15126.1 - 1.8e-05 23.9 0.1 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KOS15126.1 - 3e-05 23.4 0.2 5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KOS15126.1 - 3.1e-05 24.3 0.0 6.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS15126.1 - 5.3e-05 23.5 0.0 9.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KOS15126.1 - 0.0012 18.8 0.2 0.0019 18.2 0.2 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KOS15126.1 - 0.0021 17.6 0.1 0.0034 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KOS15126.1 - 0.012 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 KOS15126.1 - 0.013 16.3 0.0 0.026 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KOS15126.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 KOS15126.1 - 0.15 11.2 0.8 0.64 9.1 0.6 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB Sua5_yciO_yrdC PF01300.13 KOS15127.1 - 1.1e-51 174.6 0.0 2.1e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KOS15127.1 - 1.5e-28 99.3 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ran_BP1 PF00638.13 KOS15128.1 - 6.1e-50 168.3 1.4 1.1e-49 167.5 1.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 KOS15128.1 - 0.00069 19.2 2.0 0.0009 18.8 1.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 KOS15128.1 - 0.0015 18.2 0.3 0.01 15.5 0.2 2.0 1 1 0 1 1 1 1 WH1 domain PS-DH PF14765.1 KOS15128.1 - 0.079 12.1 0.1 0.45 9.6 0.0 1.9 1 1 1 2 2 2 0 Polyketide synthase dehydratase Glyco_hydro_2 PF00703.16 KOS15128.1 - 0.13 12.7 2.8 11 6.4 0.3 2.6 2 1 0 2 2 2 0 Glycosyl hydrolases family 2 EBV-NA3 PF05009.7 KOS15128.1 - 8.7 5.5 8.6 0.65 9.2 2.6 1.5 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sec10 PF07393.6 KOS15129.1 - 1e-225 751.1 0.0 1.2e-225 750.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 CENP-Q PF13094.1 KOS15129.1 - 0.076 13.0 0.0 22 5.0 0.2 2.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit INT_SG_DDX_CT_C PF15300.1 KOS15129.1 - 0.11 11.9 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus FAD_binding_1 PF00667.15 KOS15130.1 - 1e-51 175.4 0.0 1.7e-51 174.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KOS15130.1 - 6e-31 107.3 0.1 1.1e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KOS15130.1 - 9.8e-20 71.1 0.0 3.8e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KOS15130.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Ribosomal_S8e PF01201.17 KOS15131.1 - 2.3e-37 128.1 8.7 1.3e-36 125.6 6.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 KOS15131.1 - 0.027 14.3 1.9 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Mer2 Macoilin PF09726.4 KOS15131.1 - 0.73 8.0 9.7 0.98 7.6 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein LIP PF03583.9 KOS15132.1 - 8.3e-16 58.0 0.1 1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF2178 PF09946.4 KOS15133.1 - 2.3 8.0 6.5 0.83 9.4 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) ADIP PF11559.3 KOS15135.1 - 8.4 6.2 16.0 0.21 11.4 5.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2431 PF10354.4 KOS15136.1 - 1.6e-28 99.7 0.0 5.5e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Asp PF00026.18 KOS15137.1 - 2.1e-51 175.0 4.9 8.1e-51 173.1 3.4 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KOS15137.1 - 2.5e-07 31.0 0.4 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KOS15137.1 - 9.6e-05 21.9 0.0 0.00025 20.6 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KOS15137.1 - 0.00054 19.9 0.8 0.0058 16.5 0.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KOS15137.1 - 0.028 14.2 0.5 0.54 10.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease WD40 PF00400.27 KOS15138.1 - 2.7e-12 46.0 14.0 2e-05 24.2 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3071 PF11268.3 KOS15138.1 - 0.039 13.6 0.2 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Enolase_C PF00113.17 KOS15139.1 - 1.8e-144 480.2 0.2 2.5e-144 479.7 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KOS15139.1 - 1.1e-56 190.4 0.4 1.1e-56 190.4 0.3 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KOS15139.1 - 6.1e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KOS15139.1 - 0.003 16.5 0.2 0.0076 15.2 0.1 1.7 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus SAP18 PF06487.7 KOS15140.1 - 1.6e-11 44.0 0.0 2.2e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TPP_enzyme_N PF02776.13 KOS15141.1 - 9.1e-55 184.7 0.1 4.2e-54 182.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KOS15141.1 - 3.1e-49 166.4 0.4 7.1e-47 158.8 0.0 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KOS15141.1 - 2.4e-38 130.9 0.3 5.4e-38 129.8 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KOS15141.1 - 0.045 13.2 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Thiolase_N PF00108.18 KOS15142.1 - 5e-82 274.8 0.4 7.3e-82 274.2 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KOS15142.1 - 7.1e-47 157.8 0.2 2.1e-46 156.3 0.2 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KOS15142.1 - 3.3e-06 26.7 0.7 1e-05 25.1 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF4358 PF14270.1 KOS15142.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Adap_comp_sub PF00928.16 KOS15143.1 - 5.9e-68 228.8 0.0 7.2e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KOS15143.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Exo_endo_phos PF03372.18 KOS15144.1 - 2.3e-21 76.8 0.0 3.5e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KOS15144.1 - 3.7e-16 58.3 1.4 3.9e-06 26.3 0.4 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS15144.1 - 7.2e-11 41.6 1.0 1.2e-06 28.2 0.3 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KOS15144.1 - 3e-09 35.6 0.8 0.26 11.4 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KOS15144.1 - 6.4e-05 22.5 4.1 4.9 7.7 0.0 5.3 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KOS15144.1 - 0.036 14.1 1.2 26 5.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Sec23_trunk PF04811.10 KOS15145.1 - 3e-66 223.2 0.0 4.1e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KOS15145.1 - 1.2e-20 72.8 0.0 2.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KOS15145.1 - 5.6e-17 61.0 3.9 1e-16 60.1 2.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KOS15145.1 - 1.6e-15 57.3 0.0 3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KOS15145.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 KOS15145.1 - 0.00035 20.3 2.0 0.00035 20.3 1.4 1.9 2 0 0 2 2 2 1 WW domain DAO PF01266.19 KOS15146.1 - 9.1e-45 153.0 0.2 1.1e-44 152.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS15146.1 - 4.7e-07 30.1 0.7 0.0062 16.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS15146.1 - 5e-06 25.6 1.2 0.0001 21.3 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS15146.1 - 0.00017 21.5 0.6 0.0093 15.8 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KOS15146.1 - 0.00037 18.8 0.0 0.031 12.4 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 KOS15146.1 - 0.00073 19.5 0.2 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KOS15146.1 - 0.0031 16.1 0.3 1.6 7.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KOS15146.1 - 0.0063 15.6 0.1 0.28 10.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KOS15146.1 - 0.0096 15.0 0.4 0.024 13.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.13 KOS15146.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 KOS15146.1 - 0.039 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 KOS15146.1 - 0.059 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KOS15146.1 - 0.061 11.7 0.8 0.54 8.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KOS15146.1 - 0.093 12.5 0.4 12 5.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ldh_1_N PF00056.18 KOS15146.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain K_oxygenase PF13434.1 KOS15146.1 - 0.17 10.7 0.0 0.46 9.3 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Bystin PF05291.6 KOS15147.1 - 3e-131 436.8 0.0 4.3e-131 436.3 0.0 1.2 1 0 0 1 1 1 1 Bystin RF-1 PF00472.15 KOS15148.1 - 2.5e-39 133.6 1.7 2.5e-39 133.6 1.2 2.2 2 1 0 2 2 2 1 RF-1 domain PCRF PF03462.13 KOS15148.1 - 1.2e-25 89.4 0.4 3.7e-25 87.8 0.3 1.9 1 0 0 1 1 1 1 PCRF domain Secretin_N_2 PF07655.8 KOS15150.1 - 0.0063 16.8 12.5 0.012 15.9 8.6 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain FlgD PF03963.9 KOS15150.1 - 0.053 13.5 2.8 0.18 11.9 1.9 1.9 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region PAP1 PF08601.5 KOS15150.1 - 1.2 8.7 14.2 1.4 8.5 9.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Lin-8 PF03353.10 KOS15150.1 - 1.5 8.0 3.3 1.8 7.7 2.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 KOS15150.1 - 2.8 6.0 12.9 3.1 5.9 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 KOS15150.1 - 3.8 5.9 5.6 4.1 5.8 3.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2217 PF10265.4 KOS15150.1 - 6.9 5.3 7.8 7 5.2 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_BLLF1 PF05109.8 KOS15150.1 - 9.3 4.0 33.2 11 3.8 23.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RAP1 PF07218.6 KOS15150.1 - 9.6 4.1 15.0 10 4.0 10.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S5 PF00333.15 KOS15151.1 - 4.4e-28 96.8 1.5 7.6e-28 96.0 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KOS15151.1 - 2.4e-21 74.8 0.0 3.9e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L19e PF01280.15 KOS15151.1 - 0.23 11.1 3.1 0.43 10.3 2.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e Glyco_transf_22 PF03901.12 KOS15152.1 - 1.6e-82 277.8 30.8 2e-82 277.4 21.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-LITAF-like PF10601.4 KOS15152.1 - 0.27 11.1 1.4 0.91 9.4 1.0 1.9 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Prenyltrans PF00432.16 KOS15153.1 - 6.1e-31 105.6 6.6 1.4e-09 37.3 0.1 6.3 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KOS15153.1 - 2.2e-25 88.7 0.3 3.1e-13 49.6 0.2 5.4 4 1 2 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 KOS15153.1 - 2.2e-25 89.2 1.3 2e-16 60.3 0.0 5.0 2 2 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 KOS15153.1 - 1.9e-06 27.3 0.3 0.69 9.0 0.0 4.1 2 1 2 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 KOS15153.1 - 0.00018 20.8 0.0 0.027 13.6 0.0 3.7 2 1 2 5 5 5 1 A-macroglobulin complement component Cpn60_TCP1 PF00118.19 KOS15154.1 - 6.1e-124 414.2 4.0 7e-124 414.0 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ammonium_transp PF00909.16 KOS15155.1 - 4e-110 368.0 25.3 4.6e-110 367.8 17.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Na_Ca_ex PF01699.19 KOS15156.1 - 2e-38 131.1 30.3 4.6e-20 71.6 6.8 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein WD40 PF00400.27 KOS15157.1 - 5.6e-84 273.3 7.4 5.4e-09 35.5 0.0 12.5 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 KOS15157.1 - 2.6e-37 127.6 0.2 4.5e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KOS15157.1 - 2e-09 36.1 12.8 0.037 12.1 1.1 6.3 3 2 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS15157.1 - 4.9e-08 32.1 0.1 0.27 9.9 0.0 5.1 3 2 1 4 4 4 4 Nup133 N terminal like zf-met PF12874.2 KOS15158.1 - 2.5e-06 27.4 1.1 4.8e-06 26.5 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type ENTH PF01417.15 KOS15159.1 - 3e-46 156.3 0.2 5.2e-46 155.5 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KOS15159.1 - 0.0011 17.8 0.3 0.0022 16.7 0.2 1.7 1 1 0 1 1 1 1 ANTH domain PAT1 PF09770.4 KOS15159.1 - 0.94 7.6 35.3 1.2 7.2 24.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 KOS15159.1 - 1.2 7.5 33.0 2.3 6.5 22.9 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 Myc_target_1 PF15179.1 KOS15159.1 - 8.5 5.9 15.6 0.18 11.3 6.3 1.5 2 0 0 2 2 2 0 Myc target protein 1 MOZ_SAS PF01853.13 KOS15160.1 - 6.1e-86 286.4 0.4 1.1e-85 285.6 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KOS15160.1 - 3.2e-18 65.1 0.0 7.7e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DcpS_C PF11969.3 KOS15160.1 - 0.79 9.9 3.3 0.95 9.7 0.1 2.2 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Cytochrom_C PF00034.16 KOS15161.1 - 8.8e-09 36.0 0.6 7.5e-08 33.1 0.4 2.0 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KOS15161.1 - 4.3e-08 33.1 1.6 9.5e-07 28.8 1.1 2.5 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KOS15161.1 - 0.0026 17.2 1.2 0.0087 15.5 0.1 2.1 2 1 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 KOS15161.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Haem-binding domain Ras PF00071.17 KOS15162.1 - 1.5e-56 190.2 0.0 1.8e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS15162.1 - 1.3e-15 57.9 0.0 1.8e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS15162.1 - 5.7e-07 28.9 0.0 9.6e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS15162.1 - 0.00073 18.8 0.0 0.00099 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KOS15162.1 - 0.026 13.6 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GDA1_CD39 PF01150.12 KOS15163.1 - 4.6e-83 279.1 0.0 5.7e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KOS15163.1 - 0.041 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF663 PF04950.7 KOS15164.1 - 5.2e-89 298.1 0.0 5.2e-89 298.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KOS15164.1 - 1e-30 105.0 0.0 3.9e-30 103.2 0.0 2.0 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KOS15164.1 - 2.6e-06 26.9 0.1 0.00018 20.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KOS15164.1 - 1.1e-05 25.5 0.0 3.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS15164.1 - 1.7e-05 24.8 1.0 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KOS15164.1 - 7.8e-05 22.4 0.3 7.8e-05 22.4 0.2 2.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KOS15164.1 - 0.00091 18.7 0.1 0.0028 17.1 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KOS15164.1 - 0.0039 17.3 0.1 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KOS15164.1 - 0.0039 17.0 0.0 0.016 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KOS15164.1 - 0.004 17.2 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KOS15164.1 - 0.0059 16.2 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KOS15164.1 - 0.0078 15.9 0.0 0.0078 15.9 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 KOS15164.1 - 0.008 16.1 0.3 0.046 13.6 0.1 2.4 2 1 0 2 2 1 1 50S ribosome-binding GTPase cobW PF02492.14 KOS15164.1 - 0.0093 15.4 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KOS15164.1 - 0.01 16.3 1.6 0.018 15.5 0.0 2.3 2 0 0 2 2 1 0 Miro-like protein ABC_tran PF00005.22 KOS15164.1 - 0.011 15.9 0.0 0.011 15.9 0.0 2.4 3 0 0 3 3 1 0 ABC transporter AAA_17 PF13207.1 KOS15164.1 - 0.012 16.4 0.0 0.012 16.4 0.0 3.2 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KOS15164.1 - 0.027 14.3 3.4 0.044 13.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KOS15164.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS15164.1 - 0.046 13.6 0.1 0.046 13.6 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 KOS15164.1 - 1 9.6 11.5 6.6 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L18p PF00861.17 KOS15165.1 - 2.2e-44 150.4 0.7 2.8e-43 146.9 0.0 2.6 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KOS15165.1 - 1e-33 115.7 5.4 1e-33 115.7 3.8 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3340 PF11818.3 KOS15165.1 - 0.0076 16.2 2.7 0.013 15.4 1.4 1.8 1 1 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) Thr_synth_N PF14821.1 KOS15165.1 - 0.019 14.9 0.2 4.5 7.3 0.0 2.8 2 1 0 2 2 2 0 Threonine synthase N terminus MtrA PF04208.9 KOS15165.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Peptidase_M24 PF00557.19 KOS15166.1 - 9.3e-27 93.9 1.0 1.3e-26 93.4 0.7 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3588 PF12140.3 KOS15166.1 - 0.046 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) AAA_2 PF07724.9 KOS15167.1 - 8.7e-45 152.6 0.0 1.1e-41 142.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KOS15167.1 - 9.7e-25 86.2 0.3 4.1e-24 84.2 0.0 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KOS15167.1 - 2.7e-19 69.6 0.0 1.3e-09 38.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS15167.1 - 7.5e-13 48.4 0.1 1.1e-07 31.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KOS15167.1 - 4.6e-10 39.7 0.2 0.0089 16.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KOS15167.1 - 8.6e-09 35.0 0.2 1.4e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 KOS15167.1 - 1.2e-08 35.1 11.9 0.00031 20.7 0.0 5.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 KOS15167.1 - 2.5e-07 30.6 0.0 0.0089 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KOS15167.1 - 0.00011 21.6 0.0 0.05 13.0 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KOS15167.1 - 0.00015 22.0 0.4 0.53 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KOS15167.1 - 0.00033 20.4 3.5 0.018 14.7 0.0 3.3 3 1 0 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 KOS15167.1 - 0.00044 19.0 0.7 0.16 10.6 0.1 3.2 3 0 0 3 3 3 1 TIP49 C-terminus RNA_helicase PF00910.17 KOS15167.1 - 0.00052 20.1 0.1 0.49 10.6 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 KOS15167.1 - 0.00088 18.9 0.0 0.36 10.6 0.0 3.2 4 0 0 4 4 2 1 Part of AAA domain AAA_28 PF13521.1 KOS15167.1 - 0.00092 19.2 1.7 2.4 8.1 0.0 4.1 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KOS15167.1 - 0.0012 18.0 0.2 1.1 8.4 0.0 3.0 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KOS15167.1 - 0.0013 19.5 3.1 0.51 11.1 0.0 3.8 4 1 0 4 4 4 1 AAA domain SRP54 PF00448.17 KOS15167.1 - 0.002 17.6 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KOS15167.1 - 0.0037 17.6 4.3 6.8 6.9 3.7 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 KOS15167.1 - 0.0045 16.6 0.0 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 KOS15167.1 - 0.017 13.8 0.2 6.1 5.3 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 KOS15167.1 - 0.019 14.0 1.4 0.63 9.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.9 KOS15167.1 - 0.031 13.9 0.0 0.81 9.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KOS15167.1 - 0.034 14.4 0.8 17 5.6 0.0 3.3 3 0 0 3 3 3 0 ABC transporter DUF258 PF03193.11 KOS15167.1 - 0.049 12.8 0.0 0.59 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_3 PF07726.6 KOS15167.1 - 0.059 12.9 0.1 0.85 9.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KOS15167.1 - 0.061 12.9 0.8 10 5.7 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 KOS15167.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin IncA PF04156.9 KOS15167.1 - 0.28 10.7 8.6 0.79 9.2 6.0 1.8 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 KOS15167.1 - 4.1 6.2 11.9 7.4 5.4 8.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Na_Ca_ex PF01699.19 KOS15168.1 - 8.7e-25 86.9 27.5 3.7e-15 55.7 7.7 4.0 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KOS15168.1 - 3.7e-09 36.8 13.6 3.7e-09 36.8 9.4 3.8 2 0 0 2 2 2 1 Domain of unknown function (DUF307) Prenylcys_lyase PF07156.9 KOS15169.1 - 2.8e-42 144.9 0.0 8.2e-42 143.4 0.0 1.7 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KOS15169.1 - 1.6e-09 37.6 0.1 1.2e-08 34.8 0.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KOS15169.1 - 8.5e-07 28.3 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KOS15169.1 - 0.00026 20.8 0.0 0.024 14.4 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KOS15169.1 - 0.0011 18.1 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KOS15169.1 - 0.0023 16.8 0.0 0.0078 15.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS15169.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS15169.1 - 0.04 13.9 0.0 0.49 10.4 0.0 2.4 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KOS15169.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KOS15169.1 - 0.14 11.0 0.1 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A OPT PF03169.10 KOS15170.1 - 4e-158 527.6 36.5 4.6e-158 527.4 25.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short_C2 PF13561.1 KOS15171.1 - 2e-24 86.6 0.0 2.4e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KOS15171.1 - 2.7e-18 66.4 0.3 4.4e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS15171.1 - 1.3e-09 37.9 0.1 1.9e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Nucleocap_ssRNA PF11128.3 KOS15171.1 - 0.026 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid GST_N_2 PF13409.1 KOS15172.1 - 3e-15 55.9 0.0 6.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS15172.1 - 3.3e-15 55.7 0.0 6.3e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KOS15172.1 - 1.7e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS15172.1 - 0.00011 22.5 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS15172.1 - 0.0003 20.9 0.1 0.03 14.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain tRNA-synt_2 PF00152.15 KOS15173.1 - 1.5e-86 290.1 0.0 2.1e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KOS15173.1 - 6.6e-12 45.1 0.0 1.8e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KOS15173.1 - 1.4e-08 34.2 0.1 3.5e-05 23.1 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KOS15173.1 - 0.042 13.4 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 KOS15173.1 - 0.044 13.2 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like SecY PF00344.15 KOS15174.1 - 4.4e-96 321.8 13.2 5.9e-96 321.4 9.1 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KOS15174.1 - 2.4e-17 62.1 0.3 6.5e-17 60.7 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Sortase PF04203.8 KOS15174.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Sortase family FAP PF07174.6 KOS15176.1 - 0.63 9.2 29.2 0.81 8.9 20.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4349 PF14257.1 KOS15176.1 - 5.9 6.0 5.7 9 5.4 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) NUDE_C PF04880.8 KOS15176.1 - 7.5 6.8 11.9 11 6.3 8.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PRCC PF10253.4 KOS15177.1 - 1.7 9.3 6.1 0.18 12.4 0.6 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_C48 PF02902.14 KOS15178.1 - 1.7e-32 112.7 0.0 3.3e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-C2H2 PF00096.21 KOS15179.1 - 3.3e-11 42.8 29.0 2.8e-06 27.3 0.7 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS15179.1 - 3.5e-11 42.8 14.3 9.7e-05 22.4 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KOS15179.1 - 5.3e-10 38.9 16.2 0.00025 21.1 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS15179.1 - 2.9e-06 26.9 5.0 0.0017 18.1 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KOS15179.1 - 0.0011 18.5 6.4 0.041 13.5 0.2 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KOS15179.1 - 0.059 13.3 7.2 0.1 12.5 0.2 3.2 2 1 1 3 3 3 0 Zinc ribbon domain IBR PF01485.16 KOS15179.1 - 0.12 12.2 4.3 2.1 8.2 1.3 2.4 1 1 1 2 2 2 0 IBR domain zf-met PF12874.2 KOS15179.1 - 5 7.4 11.5 6.8 7.0 0.1 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KOS15179.1 - 8.9 6.0 7.6 6.7 6.4 0.1 3.5 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger RmlD_sub_bind PF04321.12 KOS15180.1 - 4e-54 183.4 0.9 4e-54 183.4 0.6 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Vps5 PF09325.5 KOS15180.1 - 1.4e-39 135.7 11.4 2.9e-39 134.7 7.9 1.4 1 0 0 1 1 1 1 Vps5 C terminal like Epimerase PF01370.16 KOS15180.1 - 4.7e-24 85.1 0.1 8.3e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 KOS15180.1 - 2.3e-23 82.1 0.1 7.4e-23 80.4 0.0 1.8 2 0 0 2 2 2 1 PX domain NAD_binding_10 PF13460.1 KOS15180.1 - 3.3e-09 37.0 1.1 5.8e-09 36.1 0.3 1.8 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KOS15180.1 - 5e-08 32.2 1.3 1.2e-06 27.6 0.0 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KOS15180.1 - 3.6e-06 26.0 1.1 0.00016 20.7 0.0 2.5 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KOS15180.1 - 0.0004 19.1 0.1 0.0017 17.0 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Arfaptin PF06456.8 KOS15180.1 - 0.003 16.9 7.5 0.06 12.6 0.9 2.3 2 0 0 2 2 2 2 Arfaptin-like domain NmrA PF05368.8 KOS15180.1 - 0.11 11.6 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family DNA_topoisoIV PF00521.15 KOS15180.1 - 0.15 10.8 1.9 0.25 10.1 1.3 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A adh_short PF00106.20 KOS15180.1 - 0.66 9.8 8.8 3.7 7.4 3.5 3.2 2 1 0 2 2 2 0 short chain dehydrogenase Bax1-I PF01027.15 KOS15181.1 - 1.4e-43 148.8 26.6 1.7e-43 148.6 18.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 KOS15181.1 - 0.13 11.6 14.2 1.4 8.3 4.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) PhaG_MnhG_YufB PF03334.9 KOS15181.1 - 9.2 6.3 10.9 0.88 9.6 3.5 2.3 2 1 1 3 3 3 0 Na+/H+ antiporter subunit PIGA PF08288.7 KOS15182.1 - 2.1e-40 136.9 0.2 2e-39 133.8 0.0 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KOS15182.1 - 5.2e-25 87.8 0.0 7.6e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS15182.1 - 2.7e-13 50.3 0.1 2.7e-13 50.3 0.1 2.0 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KOS15182.1 - 5.5e-11 42.4 0.9 1.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KOS15182.1 - 9.8e-11 41.9 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KOS15182.1 - 4.9e-07 29.6 0.0 7.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Fe-S_biosyn PF01521.15 KOS15183.1 - 8.3e-19 67.5 0.0 1.1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SUV3_C PF12513.3 KOS15183.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AA_permease PF00324.16 KOS15184.1 - 2.2e-18 65.8 3.8 5.1e-18 64.6 2.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS15184.1 - 1.3e-06 27.2 1.0 1.3e-06 27.2 0.7 1.1 1 0 0 1 1 1 1 Amino acid permease Serinc PF03348.10 KOS15185.1 - 4.2e-118 394.7 2.7 5.2e-118 394.4 1.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cyto_heme_lyase PF01265.12 KOS15186.1 - 1.1e-55 189.0 1.5 1.2e-55 188.9 1.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase WD40 PF00400.27 KOS15187.1 - 4.7e-42 140.4 20.1 3.7e-08 32.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KOS15187.1 - 0.035 13.6 0.0 3.7 7.1 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 KOS15187.1 - 0.06 12.0 0.0 0.097 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like TFIIIC_delta PF12657.2 KOS15187.1 - 0.25 11.0 3.7 5.8 6.5 1.1 3.1 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Sld5 PF05916.6 KOS15188.1 - 2.2e-19 69.7 0.3 3.1e-19 69.2 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein TFCD_C PF12612.3 KOS15189.1 - 1.5e-19 70.1 1.4 3.2e-19 69.1 0.3 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KOS15189.1 - 0.00046 20.0 9.1 0.22 11.6 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat DUF544 PF04424.8 KOS15190.1 - 4.8e-13 48.9 0.0 7.6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF3439 PF11921.3 KOS15190.1 - 2.3 8.0 14.3 6.7 6.4 9.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BCNT PF07572.7 KOS15191.1 - 2.4e-16 59.4 2.9 4.7e-16 58.5 2.0 1.5 1 1 0 1 1 1 1 Bucentaur or craniofacial development FliJ PF02050.11 KOS15191.1 - 0.044 13.8 0.5 0.09 12.8 0.1 1.6 1 1 1 2 2 2 0 Flagellar FliJ protein Yos1 PF08571.5 KOS15192.1 - 2e-17 63.0 0.1 4e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Yos1-like GEMIN8 PF15348.1 KOS15192.1 - 0.64 10.0 8.1 0.063 13.3 1.7 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 GATA PF00320.22 KOS15193.1 - 1e-15 56.7 2.1 2.6e-15 55.4 1.5 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF737 PF05300.6 KOS15194.1 - 0.61 10.0 3.1 7 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF737) ABC2_membrane_2 PF12679.2 KOS15196.1 - 1.1 8.0 11.1 2.2 7.0 7.1 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein PCI PF01399.22 KOS15198.1 - 1.5e-10 41.2 3.4 2.6e-10 40.5 0.1 3.0 3 0 0 3 3 3 1 PCI domain Peptidase_M15_2 PF05951.8 KOS15198.1 - 1.9 7.9 6.4 1.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) His_Phos_2 PF00328.17 KOS15199.1 - 6.4e-38 130.9 0.1 8.2e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4298 PF14131.1 KOS15199.1 - 0.095 12.5 0.2 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) SAM_1 PF00536.25 KOS15200.1 - 3.4e-17 62.3 0.1 7.6e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KOS15200.1 - 5.1e-14 51.8 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 KOS15200.1 - 6.3e-09 35.0 0.1 9.6e-07 28.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KOS15200.1 - 1.2e-07 31.0 0.1 0.019 14.4 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain SH3_9 PF14604.1 KOS15200.1 - 8.2e-07 28.5 1.4 0.0036 16.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.18 KOS15200.1 - 0.00042 20.7 0.0 0.00093 19.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HTH_9 PF08221.6 KOS15201.1 - 2.4e-20 72.1 0.7 6.8e-11 41.8 0.0 4.4 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 KOS15201.1 - 2e-12 47.2 0.5 1.1e-11 44.8 0.1 2.3 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 KOS15201.1 - 0.00015 21.1 0.3 0.039 13.4 0.0 3.5 3 1 1 4 4 4 1 TFIIE alpha subunit GTP1_OBG PF01018.17 KOS15202.1 - 2.2e-38 131.3 1.3 3.3e-38 130.8 0.9 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 KOS15202.1 - 1.5e-19 70.0 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS15202.1 - 4.6e-08 32.4 0.0 2.9e-07 29.9 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KOS15202.1 - 2.2e-05 24.0 0.0 0.0087 15.5 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 KOS15202.1 - 0.00014 21.1 0.0 0.0019 17.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KOS15202.1 - 0.0002 21.2 0.0 0.16 11.8 0.0 2.2 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 KOS15202.1 - 0.022 15.0 0.0 0.038 14.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter ArgK PF03308.11 KOS15202.1 - 0.052 12.3 0.0 0.9 8.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein SRPRB PF09439.5 KOS15202.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HSF_DNA-bind PF00447.12 KOS15203.1 - 4.2e-33 113.6 0.0 9.4e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF972 PF06156.8 KOS15203.1 - 0.38 11.1 5.8 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) FdhE PF04216.7 KOS15203.1 - 2.2 7.9 5.6 1.4 8.5 0.3 2.7 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation IKKbetaNEMObind PF12179.3 KOS15204.1 - 0.098 12.4 1.1 20 5.0 0.1 3.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain AAA_13 PF13166.1 KOS15204.1 - 0.44 8.9 19.0 2 6.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain Epimerase PF01370.16 KOS15205.1 - 1.1e-11 44.6 0.2 4.2e-11 42.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KOS15205.1 - 1.3e-08 33.8 1.4 6.5e-07 28.3 1.0 2.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KOS15205.1 - 2e-06 26.9 0.4 0.0024 16.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KOS15205.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Vezatin PF12632.2 KOS15207.1 - 4.5e-06 25.9 0.0 2e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes Cullin PF00888.17 KOS15208.1 - 1.1e-25 90.2 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family peroxidase PF00141.18 KOS15209.1 - 5.7e-83 277.9 0.0 4.5e-47 160.4 0.0 2.3 2 0 0 2 2 2 2 Peroxidase MCM PF00493.18 KOS15210.1 - 9.7e-135 448.6 0.0 1.9e-134 447.6 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS15210.1 - 5.1e-19 68.9 0.1 4.8e-18 65.8 0.1 2.5 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KOS15210.1 - 2.3e-07 30.6 0.0 7.6e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KOS15210.1 - 3.7e-07 29.5 0.0 0.00011 21.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KOS15210.1 - 0.00033 20.2 0.1 0.003 17.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS15210.1 - 0.00052 19.5 0.2 1.4 8.3 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain DSX_dimer PF08828.5 KOS15210.1 - 0.7 9.4 5.0 14 5.2 0.0 3.2 3 0 0 3 3 3 0 Doublesex dimerisation domain NMD3 PF04981.8 KOS15211.1 - 1.8e-77 259.6 3.6 2.6e-77 259.1 2.5 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KOS15211.1 - 0.0049 16.6 5.1 0.012 15.3 2.0 2.6 2 1 0 2 2 2 1 Double zinc ribbon GcpE PF04551.9 KOS15211.1 - 0.16 10.7 0.1 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 GcpE protein zf-C4pol PF14260.1 KOS15211.1 - 0.18 11.8 1.3 1.2 9.1 1.0 2.3 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta NinF PF05810.7 KOS15211.1 - 0.22 11.3 3.2 3.9 7.3 0.9 3.1 2 1 0 2 2 2 0 NinF protein GCS PF03074.11 KOS15212.1 - 2e-150 500.9 0.0 2.6e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase zf-HC2 PF13490.1 KOS15212.1 - 0.13 12.1 0.9 1.3 9.0 0.1 2.8 2 0 0 2 2 2 0 Putative zinc-finger His_Phos_2 PF00328.17 KOS15213.1 - 1.1e-50 173.0 0.2 1.3e-50 172.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 KOS15214.1 - 1.9e-43 149.1 0.0 2.3e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 KOS15215.1 - 2.6e-28 99.3 0.0 1.6e-17 63.8 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) CPSase_L_D2 PF02786.12 KOS15216.1 - 2.9e-80 268.4 0.0 5.8e-80 267.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KOS15216.1 - 7.1e-65 218.1 0.0 1.2e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KOS15216.1 - 4.6e-36 123.2 0.1 1.2e-35 121.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 KOS15216.1 - 8e-29 100.9 0.0 1.7e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 KOS15216.1 - 4.4e-27 94.1 0.0 9.9e-27 93.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KOS15216.1 - 1.6e-20 73.6 0.1 3.1e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KOS15216.1 - 7.6e-17 61.0 0.0 2.5e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KOS15216.1 - 9.4e-15 54.0 1.3 2.2e-14 52.8 0.5 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KOS15216.1 - 3.8e-13 48.8 0.1 2.7e-05 23.7 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KOS15216.1 - 5.1e-11 42.3 0.0 9.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KOS15216.1 - 8.6e-08 31.7 0.0 2.6e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KOS15216.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KOS15216.1 - 6e-05 22.5 0.0 0.071 12.5 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KOS15216.1 - 9.3e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KOS15216.1 - 9.4e-05 21.8 0.3 0.016 14.5 0.1 2.7 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_3 PF13437.1 KOS15216.1 - 0.0015 18.8 0.0 2.4 8.5 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 KOS15216.1 - 0.034 13.3 0.5 0.059 12.5 0.4 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KOS15216.1 - 0.072 12.2 0.0 1.3 8.1 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 KOS15216.1 - 0.25 11.0 2.0 0.76 9.4 0.3 2.4 2 1 1 3 3 2 0 Glycine cleavage H-protein Pkinase PF00069.20 KOS15217.1 - 4.6e-40 137.3 0.0 8.6e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15217.1 - 2.1e-11 43.4 0.0 4.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS15217.1 - 6.4e-05 22.8 3.1 0.00014 21.6 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS15217.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinetochor_Ybp2 PF08568.5 KOS15217.1 - 0.079 11.2 0.0 0.16 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Nipped-B_C PF12830.2 KOS15218.1 - 4.3e-41 140.6 0.1 1.4e-40 138.9 0.1 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KOS15218.1 - 6.7e-11 41.9 0.6 1.1e-07 31.6 0.1 2.9 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion BCIP PF13862.1 KOS15219.1 - 1.1e-39 135.9 0.0 1.4e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DnaJ PF00226.26 KOS15220.1 - 3.7e-16 58.6 0.1 5.7e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain UDG PF03167.14 KOS15221.1 - 3.9e-17 62.1 0.0 6.8e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DER1 PF04511.10 KOS15222.1 - 1.9e-27 96.0 1.7 2.3e-27 95.7 1.2 1.1 1 0 0 1 1 1 1 Der1-like family FHA PF00498.21 KOS15223.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KOS15223.1 - 5.3e-09 35.7 9.1 8.4e-09 35.1 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS15223.1 - 0.00023 20.8 7.3 0.00038 20.1 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KOS15223.1 - 0.00041 19.9 5.2 0.00073 19.1 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KOS15223.1 - 0.00046 20.2 5.5 0.0013 18.8 3.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS15223.1 - 0.002 17.7 8.9 0.0033 17.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS15223.1 - 0.0046 16.7 1.4 0.0086 15.8 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KOS15223.1 - 0.0073 16.3 11.9 0.012 15.6 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KOS15223.1 - 0.6 9.9 3.8 0.65 9.8 1.8 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Galactosyl_T PF01762.16 KOS15224.1 - 8.3e-09 35.3 0.8 1.7e-05 24.5 0.0 3.1 2 1 1 3 3 3 3 Galactosyltransferase Vps5 PF09325.5 KOS15225.1 - 1.3e-19 70.3 7.1 2.1e-19 69.7 4.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF1796 PF08795.5 KOS15225.1 - 0.013 15.1 0.4 0.042 13.4 0.2 1.9 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) PX PF00787.19 KOS15225.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 PX domain UQ_con PF00179.21 KOS15226.1 - 7.5e-50 168.0 0.0 8.6e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS15226.1 - 6.3e-07 29.2 0.0 8.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF3661 PF12400.3 KOS15228.1 - 2.8e-35 121.2 6.3 2.8e-35 121.2 4.3 1.5 2 0 0 2 2 2 1 Vaculolar membrane protein GDPD PF03009.12 KOS15229.1 - 2.9e-36 125.2 0.0 3.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KOS15229.1 - 0.0018 18.3 1.4 0.004 17.2 1.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pyr_redox_2 PF07992.9 KOS15230.1 - 2.9e-21 76.2 0.0 4.5e-20 72.3 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KOS15230.1 - 2.6e-12 46.1 0.0 5.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KOS15230.1 - 1.2e-10 41.5 0.6 1.7e-08 34.7 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS15230.1 - 3.8e-05 23.8 0.0 0.0003 20.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KOS15230.1 - 9.2e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 KOS15230.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Peripla_BP_6 PF13458.1 KOS15230.1 - 0.054 12.8 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein UDPG_MGDP_dh_N PF03721.9 KOS15230.1 - 0.14 11.5 0.2 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PWI PF01480.12 KOS15231.1 - 2.6e-27 94.7 0.0 3.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 PWI domain Phage_term_smal PF05944.7 KOS15231.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage small terminase subunit SRR1 PF07985.7 KOS15232.1 - 1.7e-09 37.4 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 tRNA-synt_2c PF01411.14 KOS15233.1 - 3.2e-218 725.4 0.0 4.1e-218 725.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KOS15233.1 - 3.8e-16 58.6 0.2 9.4e-16 57.4 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KOS15233.1 - 9.7e-05 22.0 0.3 0.00035 20.2 0.2 2.1 1 0 0 1 1 1 1 DHHA1 domain MBOAT PF03062.14 KOS15234.1 - 7.5e-49 166.5 4.2 7.5e-49 166.5 2.9 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkr1 PF08636.5 KOS15234.1 - 0.03 14.3 0.1 0.03 14.3 0.1 3.3 3 1 0 3 3 3 0 ER protein Pkr1 Ribosomal_60s PF00428.14 KOS15235.1 - 7.1 7.1 8.3 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Mur_ligase_M PF08245.7 KOS15236.1 - 2.6e-05 24.3 0.2 0.016 15.2 0.1 3.0 1 1 0 1 1 1 1 Mur ligase middle domain DER1 PF04511.10 KOS15237.1 - 3.9e-38 130.9 7.0 4.4e-38 130.7 4.9 1.0 1 0 0 1 1 1 1 Der1-like family DUF368 PF04018.8 KOS15237.1 - 0.004 16.3 0.6 0.0079 15.4 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF368) IMS_HHH PF11798.3 KOS15237.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif Ras PF00071.17 KOS15238.1 - 2.4e-57 192.8 0.1 2.8e-57 192.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS15238.1 - 4.4e-17 62.6 0.0 6.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS15238.1 - 2.5e-08 33.3 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KOS15238.1 - 2.1e-06 27.2 0.1 3.9e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KOS15238.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KOS15238.1 - 0.0065 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS15238.1 - 0.031 13.4 0.3 0.047 12.8 0.0 1.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AlaDh_PNT_C PF01262.16 KOS15238.1 - 0.11 12.0 0.2 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF258 PF03193.11 KOS15238.1 - 0.12 11.5 0.1 0.24 10.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KOS15238.1 - 0.53 9.7 2.6 3.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 KOS15239.1 - 1e-79 265.7 0.1 1.2e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS15239.1 - 6.2e-14 51.6 0.0 7.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KOS15239.1 - 6.8e-13 48.3 0.0 7.3e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KOS15239.1 - 5.2e-12 45.1 1.0 7.8e-09 34.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KOS15239.1 - 2.9e-11 42.9 0.0 3.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS15239.1 - 7.1e-09 36.2 0.0 9.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KOS15239.1 - 6.5e-06 26.0 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KOS15239.1 - 0.0063 15.6 0.2 0.018 14.1 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KOS15239.1 - 0.018 14.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KOS15239.1 - 0.087 12.7 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF500 PF04366.7 KOS15240.1 - 6.7e-42 141.9 0.6 1.2e-41 141.0 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) HECT PF00632.20 KOS15241.1 - 1.9e-88 296.7 0.0 2.8e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L36e PF01158.13 KOS15242.1 - 2e-36 123.8 2.4 2.3e-36 123.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.1 KOS15242.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal HD_3 PF13023.1 KOS15243.1 - 2.1e-38 131.6 2.3 2.5e-38 131.3 0.3 2.0 2 0 0 2 2 2 1 HD domain HD PF01966.17 KOS15243.1 - 0.00035 20.5 1.1 0.00035 20.5 0.8 2.3 2 1 0 2 2 2 1 HD domain SUR7 PF06687.7 KOS15244.1 - 2.1e-13 50.3 12.7 3.9e-13 49.4 8.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 KOS15244.1 - 5e-06 25.9 2.9 8.4e-06 25.1 2.0 1.3 1 0 0 1 1 1 1 Clc-like UPF0114 PF03350.11 KOS15244.1 - 0.054 13.4 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Claudin_2 PF13903.1 KOS15244.1 - 0.13 11.9 14.1 0.017 14.8 6.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WD40 PF00400.27 KOS15245.1 - 1e-13 50.5 1.6 1.4e-06 27.9 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS15245.1 - 1.8e-06 27.5 0.1 3.2e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KOS15245.1 - 0.022 14.2 0.0 0.078 12.5 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.1 KOS15245.1 - 0.024 14.8 0.4 3.2 8.1 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain 2OG-FeII_Oxy PF03171.15 KOS15246.1 - 3e-14 53.0 0.0 5.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KOS15246.1 - 0.039 14.4 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ETC_C1_NDUFA4 PF04800.7 KOS15248.1 - 1.5e-34 117.9 0.2 2.2e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region HSA PF07529.8 KOS15249.1 - 2.5e-15 56.0 5.0 2.5e-15 56.0 3.5 4.2 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 KOS15249.1 - 0.00059 19.8 1.5 0.0019 18.2 1.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRP PF06011.7 KOS15250.1 - 7.9e-66 222.4 19.2 1e-65 222.0 13.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KOS15250.1 - 6.5e-24 84.5 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Tenui_PVC2 PF06656.6 KOS15250.1 - 0.35 8.6 0.5 0.63 7.7 0.3 1.3 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Pkinase PF00069.20 KOS15251.1 - 3.9e-35 121.2 0.0 2.1e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15251.1 - 1.3e-25 90.0 0.0 6.6e-24 84.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15251.1 - 2.5e-07 29.9 0.0 4.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS15251.1 - 0.055 12.5 0.0 0.38 9.7 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KOS15251.1 - 0.13 11.5 0.0 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family PP2C PF00481.16 KOS15252.1 - 6.4e-09 35.5 0.1 0.00044 19.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KOS15252.1 - 2.3e-07 30.7 0.1 0.0041 16.8 0.0 2.6 1 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KOS15252.1 - 6.2e-05 22.4 0.0 0.00039 19.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DUF382 PF04037.8 KOS15254.1 - 7.1e-59 197.2 0.1 1.3e-58 196.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KOS15254.1 - 4.5e-19 67.5 4.8 4.5e-19 67.5 3.3 2.1 2 0 0 2 2 2 1 PSP Nop14 PF04147.7 KOS15254.1 - 1.6 6.5 9.8 2.9 5.7 6.8 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 KOS15254.1 - 3.9 5.4 6.1 6.5 4.7 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tubulin PF00091.20 KOS15255.1 - 2.9e-74 249.5 0.0 5.9e-74 248.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS15255.1 - 6.1e-45 152.3 0.0 1.2e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS15255.1 - 1.7e-05 24.8 0.0 3.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Pkinase PF00069.20 KOS15256.1 - 6.3e-60 202.5 0.1 7.3e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15256.1 - 7.3e-21 74.4 0.0 1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS15256.1 - 1.9e-07 31.0 0.1 4.7e-06 26.4 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KOS15256.1 - 0.014 14.9 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 KOS15256.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 KOS15256.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain RIO1 PF01163.17 KOS15256.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family SCO1-SenC PF02630.9 KOS15256.1 - 0.071 12.7 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 SCO1/SenC YrbL-PhoP_reg PF10707.4 KOS15256.1 - 0.28 10.5 1.5 3.9 6.7 0.0 2.4 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL KTI12 PF08433.5 KOS15257.1 - 1.1e-52 178.8 0.0 1.4e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KOS15257.1 - 5.7e-06 26.2 0.1 1.2e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS15257.1 - 0.068 13.9 0.0 0.095 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KOS15258.1 - 3.9e-65 219.5 0.0 5.9e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15258.1 - 2.7e-44 151.1 0.0 4.1e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15258.1 - 2.9e-09 36.3 0.0 1.6e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KOS15258.1 - 0.026 13.5 0.0 0.1 11.6 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS15258.1 - 0.35 10.5 6.3 0.23 11.1 0.1 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family ETF PF01012.16 KOS15259.1 - 1.7e-39 135.1 0.5 3.3e-39 134.2 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KOS15259.1 - 3e-35 119.7 1.7 3.3e-35 119.5 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.24 KOS15260.1 - 2.1e-34 118.5 0.0 3.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS15260.1 - 9.6e-10 38.7 0.2 2.2e-09 37.5 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS15260.1 - 3.2e-08 33.8 0.0 7.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS15260.1 - 2.9e-07 31.3 0.1 2.4e-06 28.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS15260.1 - 3e-06 26.7 0.2 0.029 13.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 KOS15260.1 - 6.7e-06 26.0 0.0 1.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KOS15260.1 - 8.5e-06 25.7 0.0 2.3e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KOS15260.1 - 1.8e-05 25.0 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS15260.1 - 2.7e-05 23.9 0.1 6.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KOS15260.1 - 4.2e-05 23.2 1.4 0.0002 21.0 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_24 PF13479.1 KOS15260.1 - 8.5e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KOS15260.1 - 0.00016 20.8 0.2 0.003 16.6 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS15260.1 - 0.00029 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KOS15260.1 - 0.00034 20.2 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KOS15260.1 - 0.00037 20.2 0.3 0.023 14.4 0.2 2.1 1 1 0 1 1 1 1 Archaeal ATPase Viral_helicase1 PF01443.13 KOS15260.1 - 0.00041 19.9 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KOS15260.1 - 0.00057 19.5 0.1 0.0028 17.3 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 KOS15260.1 - 0.00065 19.3 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KOS15260.1 - 0.00096 19.3 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KOS15260.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS15260.1 - 0.0022 17.1 0.0 0.005 15.9 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KOS15260.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.9 KOS15260.1 - 0.0039 16.2 0.0 0.98 8.3 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain DUF815 PF05673.8 KOS15260.1 - 0.0066 15.4 0.0 0.027 13.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 KOS15260.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KOS15260.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KOS15260.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 KOS15260.1 - 0.022 13.4 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_13 PF13166.1 KOS15260.1 - 0.029 12.8 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KOS15260.1 - 0.048 13.3 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KOS15260.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad51 PF08423.6 KOS15260.1 - 0.052 12.4 0.1 2.5 6.9 0.0 2.1 1 1 0 2 2 2 0 Rad51 PhoH PF02562.11 KOS15260.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 KOS15260.1 - 0.06 13.3 0.1 0.51 10.3 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 KOS15260.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 KOS15260.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 KOS15260.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 KOS15260.1 - 0.094 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 KOS15260.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 KOS15260.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KOS15260.1 - 0.14 11.3 0.0 0.81 8.7 0.0 1.9 1 1 1 2 2 2 0 KaiC HlyIII PF03006.15 KOS15261.1 - 8.9e-53 178.9 21.1 1.3e-52 178.4 14.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related Rhodanese PF00581.15 KOS15261.1 - 6.5e-07 29.6 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF2534 PF10749.4 KOS15261.1 - 0.036 14.0 0.8 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) DUF883 PF05957.8 KOS15261.1 - 0.22 11.9 2.0 1.9 8.9 0.6 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WD40 PF00400.27 KOS15262.1 - 1.1e-32 110.6 0.7 6.7e-09 35.2 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.4 KOS15262.1 - 2.5e-05 23.8 0.2 0.00053 19.4 0.0 2.3 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KOS15262.1 - 0.0063 14.7 0.1 0.0091 14.1 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS15262.1 - 0.031 13.0 0.6 0.13 11.0 0.4 2.3 1 1 0 1 1 1 0 Nup133 N terminal like BBS2_Mid PF14783.1 KOS15262.1 - 0.04 13.6 0.2 2.5 7.9 0.1 3.0 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF4365 PF14280.1 KOS15262.1 - 0.043 13.5 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4365) DUF3312 PF11768.3 KOS15262.1 - 0.059 11.5 0.0 0.32 9.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) SPRY PF00622.23 KOS15263.1 - 6.1e-17 61.8 0.1 9.3e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 SPRY domain ABC_membrane PF00664.18 KOS15264.1 - 2.2e-75 253.6 25.5 3.5e-38 131.5 4.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KOS15264.1 - 4.8e-59 198.5 0.0 3e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KOS15264.1 - 3.3e-12 46.0 0.0 0.00015 21.0 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KOS15264.1 - 2.7e-07 30.7 1.6 0.6 10.2 0.1 4.6 4 1 0 4 4 3 2 AAA domain AAA_21 PF13304.1 KOS15264.1 - 6e-07 29.7 0.1 0.18 11.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 KOS15264.1 - 7.1e-07 28.9 0.1 0.0065 16.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KOS15264.1 - 5e-06 25.9 0.1 0.052 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS15264.1 - 5.3e-06 26.5 6.5 0.024 14.6 1.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KOS15264.1 - 7.8e-06 24.7 0.4 0.022 13.3 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KOS15264.1 - 2.2e-05 24.2 2.8 0.24 11.3 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KOS15264.1 - 3.2e-05 24.7 0.2 0.28 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KOS15264.1 - 3.6e-05 23.2 0.4 0.23 10.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KOS15264.1 - 0.00041 20.2 0.2 1.4 8.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KOS15264.1 - 0.0014 18.9 0.1 0.3 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KOS15264.1 - 0.0026 16.9 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KOS15264.1 - 0.0041 16.9 0.2 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KOS15264.1 - 0.0053 16.4 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KOS15264.1 - 0.0065 15.9 1.6 1.2 8.5 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain G-alpha PF00503.15 KOS15264.1 - 0.009 14.7 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit APS_kinase PF01583.15 KOS15264.1 - 0.027 14.1 0.1 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.13 KOS15264.1 - 0.031 13.8 0.4 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KOS15264.1 - 0.1 11.6 0.0 19 4.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 KOS15264.1 - 0.11 11.2 0.1 0.41 9.3 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 KOS15264.1 - 0.11 12.1 0.1 19 4.9 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PALP PF00291.20 KOS15265.1 - 1.4e-72 244.5 0.4 1.8e-72 244.1 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KOS15265.1 - 1e-42 143.6 0.0 1.1e-24 85.8 0.0 3.4 2 1 1 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase Peripla_BP_6 PF13458.1 KOS15265.1 - 0.0068 15.8 0.1 0.051 12.9 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein MMR_HSR1 PF01926.18 KOS15266.1 - 9.2e-16 57.8 0.1 2e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS15266.1 - 1.8e-07 30.6 0.3 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KOS15266.1 - 7.8e-06 25.4 0.1 0.00093 18.6 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS15266.1 - 0.00092 19.0 1.4 0.29 10.9 0.1 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KOS15266.1 - 0.0038 16.4 0.1 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NUDE_C PF04880.8 KOS15267.1 - 2.7e-13 50.6 5.8 2.7e-13 50.6 4.0 3.6 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KOS15267.1 - 0.00026 21.2 25.2 0.0014 18.8 3.1 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF904) IncA PF04156.9 KOS15267.1 - 0.026 14.0 26.7 0.014 14.9 13.2 2.9 2 1 1 3 3 3 0 IncA protein ATG16 PF08614.6 KOS15267.1 - 0.037 13.8 23.2 0.15 11.8 14.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 KOS15267.1 - 0.049 13.6 0.2 0.049 13.6 0.1 4.2 3 2 2 5 5 5 0 bZIP transcription factor DUF3584 PF12128.3 KOS15267.1 - 0.071 10.4 23.6 0.0024 15.3 12.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.13 KOS15267.1 - 0.086 12.5 0.2 0.086 12.5 0.1 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF1640 PF07798.6 KOS15267.1 - 0.26 11.3 16.2 0.07 13.1 4.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) Reo_sigmaC PF04582.7 KOS15267.1 - 0.39 9.8 4.4 0.19 10.8 0.6 2.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KOS15267.1 - 0.71 10.2 19.5 2.3 8.6 2.8 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 KOS15267.1 - 0.74 9.9 9.0 0.19 11.8 0.6 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IFT57 PF10498.4 KOS15267.1 - 1.1 7.8 19.2 0.12 11.1 5.6 2.3 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 DivIC PF04977.10 KOS15267.1 - 1.5 8.3 16.5 0.14 11.6 0.7 4.1 2 1 3 5 5 5 0 Septum formation initiator FlaC_arch PF05377.6 KOS15267.1 - 2 8.3 7.7 0.61 10.0 0.1 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.16 KOS15267.1 - 3.6 6.9 25.9 1.5 8.1 4.5 3.0 2 1 1 3 3 3 0 Intermediate filament protein DMPK_coil PF08826.5 KOS15267.1 - 3.6 7.5 26.3 0.35 10.7 0.4 5.0 3 2 0 4 4 4 0 DMPK coiled coil domain like Prefoldin_2 PF01920.15 KOS15267.1 - 3.8 7.3 20.6 0.22 11.3 1.1 4.1 2 1 1 3 3 3 0 Prefoldin subunit ADIP PF11559.3 KOS15267.1 - 5.2 6.9 26.3 2.4 8.0 5.3 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 KOS15267.1 - 6.3 6.6 17.9 2.6 7.9 0.6 4.7 4 1 0 4 4 4 0 Basic region leucine zipper CCDC92 PF14916.1 KOS15267.1 - 6.5 6.4 9.2 0.46 10.1 0.2 2.8 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Peptidase_S46 PF10459.4 KOS15267.1 - 7.2 4.8 12.8 10 4.4 8.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Proteasome PF00227.21 KOS15268.1 - 4.2e-47 159.8 0.0 4.8e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF836 PF05768.9 KOS15269.1 - 8e-13 48.4 0.0 9.4e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KOS15269.1 - 0.081 13.1 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain CPDase PF07823.6 KOS15269.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Ribosomal_S13 PF00416.17 KOS15270.1 - 2.5e-22 79.3 0.0 3.3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KOS15270.1 - 0.00011 20.8 0.0 0.00015 20.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF4057 PF13266.1 KOS15270.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) Metallophos PF00149.23 KOS15271.1 - 7e-40 136.5 0.2 8.9e-40 136.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS15271.1 - 0.0014 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ARPC4 PF05856.7 KOS15272.1 - 2.1e-74 248.5 2.1 2.4e-74 248.3 1.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Fe_dep_repr_C PF02742.10 KOS15272.1 - 0.15 11.7 1.4 0.6 9.8 0.1 2.6 3 1 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain tRNA-synt_1 PF00133.17 KOS15273.1 - 4e-33 114.2 0.0 4.1e-17 61.4 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KOS15273.1 - 1.9e-15 56.4 0.0 2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KOS15273.1 - 6e-15 55.3 0.2 1.9e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KOS15273.1 - 1.1e-05 24.7 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Aminotran_1_2 PF00155.16 KOS15274.1 - 6.9e-20 71.3 0.0 9.8e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KOS15274.1 - 6.9e-06 24.8 0.0 1.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.14 KOS15274.1 - 0.0022 16.8 0.0 0.0037 16.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V TBP PF00352.16 KOS15275.1 - 9.5e-67 220.3 0.2 1.1e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KOS15275.1 - 7.2e-05 22.7 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Sugar_tr PF00083.19 KOS15276.1 - 1.1e-16 60.5 24.7 1.5e-15 56.7 17.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DNA_pol_E_B PF04042.11 KOS15277.1 - 1.8e-43 148.2 0.0 3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 KOS15277.1 - 0.037 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal E1-E2_ATPase PF00122.15 KOS15278.1 - 2.7e-27 95.2 0.3 5.3e-27 94.3 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 KOS15278.1 - 6.2e-27 93.8 0.0 1.4e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 KOS15278.1 - 7.4e-25 88.2 0.0 1.8e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS15278.1 - 1.5e-24 87.5 0.0 3.2e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KOS15278.1 - 4.6e-06 26.2 6.8 1.5e-05 24.6 4.7 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KOS15278.1 - 1.7e-05 24.6 0.0 6.1e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KOS15278.1 - 0.0042 16.5 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS15278.1 - 0.36 10.3 0.0 0.81 9.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CHCH PF06747.8 KOS15279.1 - 2.2e-07 30.6 5.0 4.4e-07 29.6 3.5 1.5 1 0 0 1 1 1 1 CHCH domain THDPS_M PF14789.1 KOS15279.1 - 0.018 14.9 0.8 2.1 8.3 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle DnaJ PF00226.26 KOS15280.1 - 8.9e-22 76.5 0.1 8.9e-22 76.5 0.1 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KOS15280.1 - 2.8e-19 68.5 17.8 1.2e-08 34.4 1.0 5.4 3 3 3 6 6 6 6 TPR repeat TPR_16 PF13432.1 KOS15280.1 - 6.4e-15 55.3 20.1 6.7e-05 23.4 0.1 6.0 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15280.1 - 2.7e-12 45.5 14.0 0.087 12.7 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 KOS15280.1 - 2.1e-11 42.9 6.8 0.064 12.8 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15280.1 - 7.6e-11 41.3 6.9 0.06 13.5 0.0 5.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15280.1 - 1.1e-09 37.9 15.5 0.00015 21.5 0.9 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15280.1 - 1.6e-09 37.9 29.8 0.00022 21.5 2.0 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15280.1 - 1.6e-08 34.4 19.2 0.16 12.6 0.7 8.7 4 3 5 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS15280.1 - 2.5e-05 23.7 5.6 0.38 10.6 0.0 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KOS15280.1 - 3.7e-05 24.0 13.5 0.013 15.7 1.3 3.8 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_8 PF13181.1 KOS15280.1 - 0.00037 20.0 6.3 9.3 6.2 0.1 5.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KOS15280.1 - 0.00066 19.7 13.7 0.013 15.5 0.1 4.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KOS15280.1 - 0.0022 17.8 17.3 0.039 13.9 1.4 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 KOS15280.1 - 0.0059 16.6 15.4 0.012 15.6 0.9 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15280.1 - 0.068 13.6 16.4 2.7 8.6 1.1 7.7 9 1 0 9 9 7 0 Tetratricopeptide repeat PPR PF01535.15 KOS15280.1 - 0.15 12.1 1.2 11 6.1 0.2 4.1 4 0 0 4 4 4 0 PPR repeat TPR_4 PF07721.9 KOS15280.1 - 0.53 10.8 8.0 2.7 8.6 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KOS15280.1 - 4.9 7.1 14.6 0.33 10.8 0.6 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain FIVAR PF07554.8 KOS15280.1 - 7.6 6.8 9.3 2.9 8.2 0.3 3.4 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain Ytp1 PF10355.4 KOS15281.1 - 2.9e-77 259.5 23.5 4e-76 255.7 11.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KOS15281.1 - 2.6e-25 88.0 2.7 2.6e-25 88.0 1.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3403 PF11883.3 KOS15281.1 - 0.23 11.7 0.4 8.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) adh_short PF00106.20 KOS15282.1 - 1.3e-27 96.7 0.5 1.8e-27 96.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS15282.1 - 1.3e-16 60.7 0.6 1.9e-16 60.2 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS15282.1 - 9.5e-08 32.2 0.0 1.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KOS15282.1 - 1.8e-05 24.6 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KOS15282.1 - 0.003 16.6 0.1 0.0062 15.6 0.0 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.21 KOS15282.1 - 0.023 14.2 0.2 0.14 11.7 0.2 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 KOS15282.1 - 0.041 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 KOS15282.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.16 KOS15282.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KOS15282.1 - 0.11 12.2 1.3 0.2 11.4 0.3 1.9 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Arginase PF00491.16 KOS15283.1 - 3e-87 292.4 0.0 4.1e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KOS15283.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Pterin_bind PF00809.17 KOS15284.1 - 1.6e-64 217.1 0.0 2.5e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KOS15284.1 - 3.4e-40 136.6 0.0 7.6e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 KOS15284.1 - 3.4e-34 117.3 0.0 1.5e-18 66.9 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase FYVE_2 PF02318.11 KOS15285.1 - 0.026 14.4 2.2 0.25 11.2 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.2 KOS15285.1 - 0.074 12.8 3.6 0.19 11.5 2.5 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 KOS15285.1 - 0.17 12.0 0.8 0.39 10.9 0.5 1.6 1 1 0 1 1 1 0 CHY zinc finger DUF1610 PF07754.6 KOS15285.1 - 0.35 11.0 2.7 0.69 10.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Ribosomal_L37ae PF01780.14 KOS15285.1 - 0.37 10.7 2.7 5.4 6.9 0.1 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 KOS15285.1 - 0.63 9.7 2.1 0.46 10.1 0.3 1.6 2 0 0 2 2 2 0 Replication factor-A C terminal domain Rubredoxin PF00301.15 KOS15285.1 - 1.5 8.7 6.4 10 6.0 0.1 3.0 3 0 0 3 3 3 0 Rubredoxin zf-piccolo PF05715.8 KOS15285.1 - 2.6 8.1 5.4 7 6.7 0.1 2.3 1 1 1 2 2 2 0 Piccolo Zn-finger DUF202 PF02656.10 KOS15286.1 - 3.1e-12 46.5 6.8 3.1e-12 46.5 4.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 KOS15286.1 - 0.052 13.2 0.3 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4131 PF13567.1 KOS15286.1 - 4.8 6.5 6.5 8.7 5.7 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Vps53_N PF04100.7 KOS15287.1 - 9.1e-75 251.8 1.2 1.5e-74 251.1 0.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 KOS15287.1 - 0.00011 20.4 0.0 0.00054 18.1 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec6 ORC5_C PF14630.1 KOS15287.1 - 0.088 12.2 4.1 0.57 9.5 0.1 3.1 2 1 1 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus APG6 PF04111.7 KOS15287.1 - 5.9 5.8 8.7 3.2 6.6 4.3 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 EF-hand_1 PF00036.27 KOS15288.1 - 2.4e-27 92.1 10.9 1.8e-07 29.9 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KOS15288.1 - 3e-23 81.7 2.1 1.9e-11 43.9 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KOS15288.1 - 3.6e-21 73.0 7.2 4.8e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KOS15288.1 - 3.1e-20 70.5 11.9 4.4e-05 22.6 0.3 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KOS15288.1 - 1.6e-15 56.4 13.9 0.0041 16.7 1.3 4.7 2 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KOS15288.1 - 2.4e-07 30.7 0.0 0.0083 16.1 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KOS15288.1 - 7.7e-06 25.5 4.8 0.54 10.0 0.3 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KOS15288.1 - 0.00013 21.7 0.1 3 7.8 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain DUF3164 PF11363.3 KOS15288.1 - 0.035 13.4 0.2 0.27 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) TerB PF05099.8 KOS15288.1 - 0.1 12.3 0.3 13 5.5 0.0 2.6 2 1 0 2 2 2 0 Tellurite resistance protein TerB SNF2_N PF00176.18 KOS15289.1 - 1.2e-67 227.7 0.2 2e-67 227.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KOS15289.1 - 1.1e-29 102.5 0.6 4.7e-29 100.5 0.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 KOS15289.1 - 9.1e-16 57.5 0.0 4.6e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 KOS15289.1 - 1e-15 57.1 0.1 9.9e-11 41.1 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 KOS15289.1 - 2.5e-06 27.4 0.0 3.4e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS15289.1 - 0.00014 21.3 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2422 PF10337.4 KOS15289.1 - 0.14 10.9 6.7 0.7 8.6 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) AMP-binding PF00501.23 KOS15290.1 - 1.6e-49 168.4 0.0 2.5e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Gar1 PF04410.9 KOS15290.1 - 8.2e-41 139.0 0.1 1.9e-40 137.8 0.1 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MmgE_PrpD PF03972.9 KOS15291.1 - 3.5e-158 526.4 0.3 3.5e-158 526.4 0.2 1.4 2 0 0 2 2 2 1 MmgE/PrpD family Pkinase PF00069.20 KOS15292.1 - 1.9e-54 184.5 0.0 3.7e-54 183.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15292.1 - 2.7e-21 75.8 0.0 4.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS15292.1 - 0.0022 17.7 0.2 0.0051 16.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KOS15292.1 - 0.026 13.8 0.1 0.058 12.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Zip PF02535.17 KOS15292.1 - 8.4 5.2 11.3 0.049 12.6 2.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Put_Phosphatase PF06888.7 KOS15293.1 - 6.9e-53 179.2 0.0 8e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 KOS15293.1 - 1.7e-05 25.1 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS15293.1 - 0.00032 20.9 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP_bind_1 PF03029.12 KOS15294.1 - 5.9e-75 251.8 0.0 6.6e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KOS15294.1 - 0.00023 20.7 0.0 0.00026 20.5 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 KOS15294.1 - 0.0019 17.9 0.1 0.0063 16.2 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KOS15294.1 - 0.0034 18.1 1.4 0.012 16.3 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS15294.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KOS15294.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KOS15294.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS15294.1 - 0.079 13.2 0.1 0.3 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KOS15294.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KOS15294.1 - 0.13 11.6 0.6 6.1 6.1 0.0 3.0 3 1 1 4 4 4 0 AAA domain MobB PF03205.9 KOS15294.1 - 0.15 11.7 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KOS15294.1 - 0.16 11.9 0.0 0.86 9.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase RhoGEF PF00621.15 KOS15295.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glyco_trans_4_3 PF12000.3 KOS15295.1 - 0.092 12.3 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group PALP PF00291.20 KOS15296.1 - 2.4e-62 210.9 0.1 3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1b PF00579.20 KOS15297.1 - 6.9e-20 71.3 0.0 2.1e-19 69.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF914 PF06027.7 KOS15298.1 - 6.8e-09 35.0 2.8 1.2e-08 34.1 2.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KOS15298.1 - 0.0022 18.1 7.3 0.0022 18.1 5.1 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KOS15298.1 - 2.9 7.9 29.2 0.031 14.3 7.0 2.4 2 0 0 2 2 2 0 EamA-like transporter family Chitin_synth_2 PF03142.10 KOS15299.1 - 1.5e-228 759.4 0.0 2.7e-228 758.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KOS15299.1 - 8.8e-16 58.1 6.8 8.8e-16 58.1 4.7 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KOS15299.1 - 2e-14 53.9 0.1 8.1e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KOS15299.1 - 4.4e-07 29.6 0.0 9.4e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KOS15299.1 - 1.2e-05 24.6 0.1 0.078 12.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_1_4 PF13692.1 KOS15300.1 - 2.6e-22 79.4 0.1 1e-21 77.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KOS15300.1 - 3.6e-09 36.9 12.5 3.6e-09 36.9 8.7 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KOS15300.1 - 3.5e-05 23.2 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KOS15300.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 KOS15301.1 - 7.3e-66 221.4 1.9 7.3e-66 221.4 1.3 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS15301.1 - 4.8e-34 117.4 9.8 4.8e-34 117.4 6.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS15301.1 - 5.5e-30 105.3 0.0 1.2e-23 84.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS15301.1 - 6.1e-15 54.9 0.0 1.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS15301.1 - 6.8e-15 55.7 0.0 1.4e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS15301.1 - 6.9e-15 54.2 0.0 6.9e-15 54.2 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS15301.1 - 0.00039 20.0 0.3 0.0073 15.9 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fibrillarin PF01269.12 KOS15302.1 - 1.4e-110 367.6 0.0 1.8e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KOS15302.1 - 1.9e-05 24.2 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KOS15302.1 - 0.0092 15.5 0.1 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KOS15302.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rdx PF10262.4 KOS15303.1 - 1.9e-19 69.4 0.0 2.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Rdx family NAD_binding_1 PF00175.16 KOS15304.1 - 7.2e-27 94.1 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KOS15304.1 - 2.9e-18 65.8 0.0 5.9e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KOS15304.1 - 4.6e-07 29.8 0.0 6.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KOS15304.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Avl9 PF09794.4 KOS15305.1 - 6.7e-133 442.8 0.0 8.7e-133 442.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KOS15305.1 - 4.3e-08 32.7 1.6 1.9e-07 30.6 0.2 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KOS15305.1 - 2.5e-07 30.3 0.5 0.00037 20.1 0.0 2.5 1 1 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 KOS15305.1 - 0.0066 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DEAD PF00270.24 KOS15306.1 - 1.7e-45 154.5 0.0 1.6e-44 151.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15306.1 - 7.7e-24 83.3 0.0 5.3e-23 80.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KOS15306.1 - 0.00081 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KOS15306.1 - 0.033 14.0 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NAP PF00956.13 KOS15307.1 - 4.6e-77 258.4 6.8 4.6e-77 258.4 4.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) PBP1_TM PF14812.1 KOS15307.1 - 0.026 14.8 3.5 0.026 14.8 2.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KOS15307.1 - 0.39 10.2 33.5 0.14 11.6 6.2 3.2 3 0 0 3 3 3 0 Nucleoplasmin Nop14 PF04147.7 KOS15307.1 - 0.43 8.4 25.4 0.011 13.6 1.8 2.3 2 0 0 2 2 2 0 Nop14-like family Striatin PF08232.7 KOS15307.1 - 2.6 8.3 7.9 2.6 8.3 3.8 2.1 2 0 0 2 2 2 0 Striatin family DEAD PF00270.24 KOS15308.1 - 1.3e-39 135.4 0.0 2.9e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15308.1 - 3.3e-20 71.7 0.1 1.5e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KOS15308.1 - 4.1e-18 64.9 2.7 1.4e-17 63.2 0.2 2.8 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.10 KOS15308.1 - 4.6e-05 23.3 0.0 0.00017 21.4 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_pol_Rpc34 PF05158.7 KOS15309.1 - 1.1e-67 228.5 0.0 1.5e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HxlR PF01638.12 KOS15309.1 - 0.067 12.8 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Rrf2 PF02082.15 KOS15309.1 - 0.14 12.3 0.2 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator Presenilin PF01080.12 KOS15309.1 - 1.2 7.9 6.5 1.7 7.4 4.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.9 KOS15309.1 - 5.2 4.9 10.8 0.77 7.7 4.6 1.6 2 0 0 2 2 2 0 CDC45-like protein Flg_bbr_C PF06429.8 KOS15310.1 - 0.011 15.5 1.3 0.04 13.8 0.9 1.9 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Sybindin PF04099.7 KOS15311.1 - 5.5e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family PWWP PF00855.12 KOS15312.1 - 5.6e-19 68.1 0.4 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 KOS15312.1 - 2.5e-05 23.7 0.0 5.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain USP8_dimer PF08969.6 KOS15312.1 - 0.044 13.7 0.5 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 USP8 dimerisation domain SRP-alpha_N PF04086.8 KOS15312.1 - 0.17 11.2 9.9 0.24 10.7 6.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hex_IIIa PF02455.11 KOS15312.1 - 3.2 6.3 7.0 4 6.0 4.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Hid1 PF12722.2 KOS15312.1 - 3.9 5.0 4.6 4.3 4.9 3.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 KOS15312.1 - 4.5 5.1 9.3 5.7 4.8 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein BRE1 PF08647.6 KOS15313.1 - 1.5e-18 66.5 8.8 1.5e-18 66.5 6.1 6.8 6 1 0 7 7 7 1 BRE1 E3 ubiquitin ligase zf-RING_5 PF14634.1 KOS15313.1 - 7.6e-07 28.7 11.3 1.4e-06 27.9 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS15313.1 - 1.8e-06 27.8 11.3 3e-06 27.1 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15313.1 - 1.2e-05 24.8 11.8 2e-05 24.1 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS15313.1 - 2.4e-05 23.8 8.0 4.4e-05 23.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS15313.1 - 0.00025 20.8 9.4 0.00043 20.0 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KOS15313.1 - 0.00054 19.6 3.4 0.00098 18.8 2.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Lebercilin PF15619.1 KOS15313.1 - 0.0013 18.2 19.5 0.0013 18.2 13.5 5.5 2 2 2 5 5 3 1 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 KOS15313.1 - 0.013 15.4 1.3 0.013 15.4 0.9 7.1 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding zf-rbx1 PF12678.2 KOS15313.1 - 0.063 13.3 4.4 0.13 12.3 3.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger UPF0547 PF10571.4 KOS15313.1 - 0.18 11.5 1.1 0.4 10.4 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_UBOX PF13445.1 KOS15313.1 - 0.27 10.9 4.5 0.6 9.8 3.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 KOS15313.1 - 0.32 10.8 5.0 0.84 9.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 KOS15313.1 - 0.45 10.4 7.7 0.82 9.5 5.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Reo_sigmaC PF04582.7 KOS15313.1 - 0.85 8.7 26.6 0.069 12.3 2.0 4.5 3 2 1 4 4 4 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KOS15313.1 - 4.1 4.9 89.1 0.14 9.8 18.8 4.3 3 1 1 4 4 4 0 Myosin tail zf-ribbon_3 PF13248.1 KOS15313.1 - 4.9 6.4 6.6 16 4.8 4.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain MRC1 PF09444.5 KOS15314.1 - 2.7e-18 66.6 19.2 2.7e-18 66.6 13.3 3.3 3 1 0 3 3 3 1 MRC1-like domain Packaging_FI PF14000.1 KOS15315.1 - 0.075 13.2 4.2 0.6 10.3 0.2 2.4 2 0 0 2 2 2 0 DNA packaging protein FI MCM2_N PF12619.3 KOS15315.1 - 0.97 9.4 7.4 2.2 8.2 5.1 1.6 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 DUF4219 PF13961.1 KOS15315.1 - 2.7 7.4 5.0 0.72 9.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) ALIX_LYPXL_bnd PF13949.1 KOS15315.1 - 4.7 6.0 8.7 0.39 9.6 1.6 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Ku PF02735.11 KOS15316.1 - 2.3e-30 105.4 0.0 4.1e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KOS15316.1 - 3.4e-23 82.2 0.0 5.7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KOS15316.1 - 7.2e-05 22.1 0.0 0.00044 19.6 0.0 2.4 3 0 0 3 3 3 1 SAP domain Ku_C PF03730.9 KOS15316.1 - 0.022 15.2 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Myb_DNA-binding PF00249.26 KOS15318.1 - 9.8e-12 44.7 1.0 2.7e-11 43.3 0.7 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS15318.1 - 7.6e-08 32.3 0.7 1.7e-07 31.2 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain UCH PF00443.24 KOS15319.1 - 7.6e-52 176.0 0.0 9.7e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS15319.1 - 6e-20 71.8 0.0 8.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KOS15319.1 - 0.0011 18.3 0.0 0.095 11.9 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase NOB1_Zn_bind PF08772.6 KOS15320.1 - 1.2e-28 98.7 0.3 2.4e-28 97.7 0.2 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_60s PF00428.14 KOS15320.1 - 1e-05 25.8 1.2 2.9e-05 24.3 0.8 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF802 PF05650.6 KOS15320.1 - 0.22 11.6 4.7 0.48 10.5 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF802) RRP7 PF12923.2 KOS15320.1 - 0.28 11.2 4.5 0.077 13.0 0.6 1.9 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) AF1Q PF15017.1 KOS15320.1 - 1.6 8.6 14.9 1.2 9.0 0.6 3.2 2 1 1 3 3 3 0 Drug resistance and apoptosis regulator CAP_GLY PF01302.20 KOS15321.1 - 3.5e-17 61.8 0.0 5.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KOS15321.1 - 5.1e-05 22.7 0.2 0.83 9.3 0.1 4.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS15321.1 - 0.0011 18.7 7.2 0.83 9.4 0.1 4.1 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 KOS15321.1 - 0.0023 17.7 1.6 1.9 8.8 0.1 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 KOS15321.1 - 0.057 13.6 8.2 12 6.6 0.1 5.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KOS15321.1 - 0.45 10.7 1.7 1.1e+02 3.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Palm_thioest PF02089.10 KOS15322.1 - 3.6e-59 200.0 0.0 4.6e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 KOS15322.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS15322.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4188 PF13826.1 KOS15322.1 - 0.085 12.9 1.4 0.25 11.4 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4188) Glyco_hydro_16 PF00722.16 KOS15323.1 - 2e-08 33.7 0.0 3.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 T2SF PF00482.18 KOS15326.1 - 0.12 12.3 0.5 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Mod_r PF07200.8 KOS15327.1 - 2.1e-18 66.6 7.0 7e-18 64.9 4.9 1.8 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.1 KOS15327.1 - 0.0097 15.9 10.2 0.09 12.7 7.1 2.1 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF2353 PF09789.4 KOS15327.1 - 0.014 14.6 3.5 0.34 10.1 0.8 2.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 KOS15327.1 - 0.029 13.8 0.7 0.029 13.8 0.5 2.1 2 1 0 2 2 2 0 Septum formation initiator LPP PF04728.8 KOS15327.1 - 0.033 13.9 0.9 0.56 10.0 0.1 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper EzrA PF06160.7 KOS15327.1 - 0.039 12.1 4.5 0.051 11.7 3.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Cep57_CLD_2 PF14197.1 KOS15327.1 - 0.075 12.9 6.9 0.031 14.2 1.6 2.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KOS15327.1 - 0.16 12.3 3.7 0.74 10.1 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RP-C PF03428.8 KOS15327.1 - 0.2 11.1 4.1 1 8.8 0.7 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain Tropomyosin_1 PF12718.2 KOS15327.1 - 0.25 11.1 9.4 0.15 11.9 2.8 1.9 1 1 1 2 2 2 0 Tropomyosin like APG6 PF04111.7 KOS15327.1 - 0.35 9.8 6.1 0.49 9.3 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KOS15327.1 - 0.49 10.0 6.4 0.44 10.1 3.0 1.7 1 1 1 2 2 2 0 Mnd1 family GrpE PF01025.14 KOS15327.1 - 0.82 9.1 6.3 1.5 8.3 4.4 1.6 1 1 0 1 1 1 0 GrpE AAA_16 PF13191.1 KOS15327.1 - 0.97 9.3 8.1 4.5 7.2 5.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain MutS_III PF05192.13 KOS15327.1 - 1.2 8.8 5.2 1.9 8.2 3.6 1.4 1 1 0 1 1 1 0 MutS domain III DUF4404 PF14357.1 KOS15327.1 - 1.4 9.4 9.9 7.4 7.0 3.9 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4404) DIM1 PF02966.11 KOS15328.1 - 4.6e-66 220.3 0.4 5.1e-66 220.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KOS15328.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KOS15328.1 - 0.015 15.3 0.1 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 KOS15328.1 - 0.055 13.5 0.2 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like ATP-synt_G PF04718.10 KOS15329.1 - 5.6e-19 68.7 0.1 1.1e-18 67.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit CPSF73-100_C PF11718.3 KOS15330.1 - 1.5e-49 168.2 0.6 1.4e-48 165.1 0.4 2.0 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KOS15330.1 - 2.3e-31 108.3 0.0 4.2e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KOS15330.1 - 7.6e-14 51.8 0.2 1.4e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS15330.1 - 2.8e-11 43.3 0.3 9.7e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KOS15330.1 - 5.2e-11 42.1 0.1 1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KOS15330.1 - 1.3e-06 28.1 0.0 6.3e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cullin PF00888.17 KOS15331.1 - 4.2e-146 487.8 0.0 1.7e-145 485.8 0.0 1.9 2 1 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KOS15331.1 - 7.3e-30 102.6 1.5 1.6e-29 101.5 1.0 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Rrf2 PF02082.15 KOS15331.1 - 0.027 14.5 0.1 0.11 12.6 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator Ribonuc_red_lgN PF00317.16 KOS15331.1 - 0.23 11.2 2.1 18 5.2 0.0 3.5 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Mito_carr PF00153.22 KOS15332.1 - 2.9e-72 238.4 1.0 5.7e-24 83.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein eIF3g PF12353.3 KOS15333.1 - 7.9e-41 138.9 1.2 1.2e-40 138.3 0.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KOS15333.1 - 6.8e-19 67.2 0.0 1.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15333.1 - 1.8e-15 56.6 0.0 3.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15333.1 - 3.6e-09 36.3 0.0 6.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS15333.1 - 0.092 12.5 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF2782 PF11191.3 KOS15333.1 - 0.37 10.7 2.6 0.88 9.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) Ribosomal_S13 PF00416.17 KOS15334.1 - 8e-40 135.5 1.3 9.5e-40 135.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KOS15334.1 - 0.0018 16.8 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 KOS15334.1 - 0.0068 15.2 0.0 0.0087 14.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) HHH_6 PF14579.1 KOS15334.1 - 0.082 12.9 0.1 0.28 11.2 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif TPR_2 PF07719.12 KOS15335.1 - 2.7e-33 111.1 20.5 7.6e-05 22.3 0.0 10.4 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 KOS15335.1 - 1.3e-28 98.4 19.3 5.8e-12 45.0 0.1 7.7 5 1 2 8 8 8 6 TPR repeat TPR_1 PF00515.23 KOS15335.1 - 2.7e-26 90.0 11.0 9.5e-05 21.8 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 KOS15335.1 - 2.5e-22 78.8 10.7 1.3e-10 41.2 0.0 6.3 5 2 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KOS15335.1 - 1.7e-19 69.5 18.5 3.6e-10 39.6 0.0 8.4 5 1 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15335.1 - 2.5e-19 67.5 0.0 0.00043 19.8 0.0 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15335.1 - 2.2e-16 60.0 46.3 1.6e-11 44.5 0.2 9.2 8 1 4 12 12 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15335.1 - 6.7e-14 51.9 23.0 0.028 14.7 0.6 8.1 7 2 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15335.1 - 2.9e-13 49.1 32.5 0.074 13.7 0.5 10.3 5 2 6 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 KOS15335.1 - 4.4e-13 47.9 11.0 0.009 15.7 0.0 8.5 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15335.1 - 5e-11 42.2 22.7 0.16 12.5 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15335.1 - 6.1e-11 41.6 4.9 5.5 7.4 0.0 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 KOS15335.1 - 3.6e-07 29.8 21.3 0.029 14.3 0.0 6.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_4 PF07721.9 KOS15335.1 - 0.021 15.2 29.3 0.15 12.6 0.4 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15335.1 - 0.12 12.1 16.1 1.6 8.6 0.1 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KOS15335.1 - 0.21 11.4 3.8 3.8 7.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 KOS15335.1 - 0.86 10.0 3.3 18 5.9 0.0 4.0 4 0 0 4 4 3 0 Pentatricopeptide repeat domain HORMA PF02301.13 KOS15336.1 - 8.2e-45 152.8 0.3 9.3e-45 152.6 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF1682 PF07946.9 KOS15336.1 - 0.014 14.2 0.2 0.015 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1649 PF07855.7 KOS15336.1 - 0.065 12.8 0.5 0.25 10.9 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1649) MFS_1 PF07690.11 KOS15337.1 - 1.2e-25 89.9 39.6 1.3e-21 76.6 7.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS15337.1 - 5.5e-06 25.2 1.4 5.5e-06 25.2 1.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2370 PF10176.4 KOS15337.1 - 0.0085 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) EamA PF00892.15 KOS15338.1 - 5.9e-07 29.5 9.2 5.9e-07 29.5 6.4 3.1 4 0 0 4 4 4 2 EamA-like transporter family EF-hand_4 PF12763.2 KOS15339.1 - 1.8e-36 124.0 0.0 4.2e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KOS15339.1 - 9e-11 41.7 0.0 6.6e-05 22.9 0.0 4.7 4 1 0 4 4 4 2 EF-hand domain pair UBA PF00627.26 KOS15339.1 - 5.2e-07 29.3 0.4 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 KOS15339.1 - 3.1e-06 26.0 0.0 0.077 12.3 0.0 5.0 6 0 0 6 6 6 1 EF hand EF-hand_6 PF13405.1 KOS15339.1 - 5.4e-06 25.8 0.0 0.38 10.7 0.0 5.5 6 0 0 6 6 6 1 EF-hand domain Macoilin PF09726.4 KOS15339.1 - 4e-05 22.1 3.8 6.1e-05 21.5 2.6 1.3 1 0 0 1 1 1 1 Transmembrane protein MAD PF05557.8 KOS15339.1 - 0.00019 19.6 14.5 0.00028 19.1 10.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein EF-hand_8 PF13833.1 KOS15339.1 - 0.0098 15.4 0.0 4.6 6.9 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair UBA_3 PF09288.5 KOS15339.1 - 0.038 13.6 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain IncA PF04156.9 KOS15339.1 - 0.19 11.2 28.0 1.1 8.8 19.5 2.0 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 KOS15339.1 - 0.25 11.2 28.4 1.6 8.6 10.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 KOS15339.1 - 1.1 7.5 9.5 1.6 7.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF16 PF01519.11 KOS15339.1 - 1.5 9.0 5.8 3.1 8.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Reo_sigmaC PF04582.7 KOS15339.1 - 1.7 7.7 7.7 3.5 6.7 5.0 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 KOS15339.1 - 4.4 6.6 25.1 16 4.8 17.5 1.6 1 1 0 1 1 1 0 Intermediate filament protein DUF641 PF04859.7 KOS15339.1 - 4.5 7.0 16.4 0.91 9.2 5.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 KOS15339.1 - 4.8 7.3 10.3 2.6 8.1 5.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0052 PF01933.13 KOS15340.1 - 9.5e-28 97.3 0.0 6.7e-27 94.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised protein family UPF0052 MgtE PF01769.11 KOS15341.1 - 6.3e-18 65.3 19.7 1.9e-07 31.4 0.1 4.7 5 0 0 5 5 5 3 Divalent cation transporter Ku PF02735.11 KOS15342.1 - 4.7e-22 78.3 0.0 7.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 KOS15342.1 - 0.005 16.9 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Patatin PF01734.17 KOS15342.1 - 0.11 12.3 0.7 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 Patatin-like phospholipase RhoGAP PF00620.22 KOS15344.1 - 4e-39 133.6 0.0 9e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KOS15344.1 - 4.6e-12 45.8 22.1 1e-07 31.9 2.8 3.5 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 KOS15344.1 - 2.9e-05 23.6 7.2 2.9e-05 23.6 5.0 4.1 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2321 PF10083.4 KOS15344.1 - 0.0046 16.4 1.5 0.087 12.3 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) Mnd1 PF03962.10 KOS15344.1 - 0.32 10.6 2.2 0.6 9.7 1.5 1.3 1 0 0 1 1 1 0 Mnd1 family Apc4 PF12896.2 KOS15345.1 - 3e-32 111.6 0.6 4.4e-32 111.0 0.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PAP_assoc PF03828.14 KOS15346.1 - 3e-17 62.3 0.0 6.7e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KOS15346.1 - 5.5e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF925 PF06042.6 KOS15346.1 - 0.17 11.4 1.6 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF925) SIR2 PF02146.12 KOS15347.1 - 1.3e-26 93.4 0.1 1.5e-19 70.3 0.0 3.1 3 0 0 3 3 3 2 Sir2 family DUF3439 PF11921.3 KOS15347.1 - 0.00056 19.6 5.1 0.0015 18.2 3.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) CBP4 PF07960.6 KOS15348.1 - 7.9e-14 51.3 0.0 9.7e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 CBP4 DUF4164 PF13747.1 KOS15348.1 - 0.0035 17.4 1.5 0.004 17.2 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) SBP_bac_7 PF03480.8 KOS15348.1 - 0.027 13.5 0.3 0.031 13.3 0.2 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF4574 PF15141.1 KOS15348.1 - 0.043 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) MAS20 PF02064.10 KOS15348.1 - 0.046 13.6 0.7 0.06 13.2 0.5 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor HSP70 PF00012.15 KOS15349.1 - 5.2e-265 880.0 14.0 5.8e-265 879.8 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KOS15349.1 - 1e-19 70.3 1.0 1.8e-17 62.9 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KOS15349.1 - 3.3e-05 23.1 2.5 0.023 13.8 0.1 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase HAP1_N PF04849.8 KOS15349.1 - 0.03 13.2 2.9 0.05 12.5 2.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FGGY_C PF02782.11 KOS15349.1 - 0.06 12.9 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF2680 PF10925.3 KOS15349.1 - 0.11 12.3 4.5 2.2 8.2 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) ScpA_ScpB PF02616.9 KOS15349.1 - 1.3 8.5 8.4 0.07 12.6 1.5 2.0 2 0 0 2 2 2 0 ScpA/B protein Spectrin PF00435.16 KOS15349.1 - 1.6 9.0 7.9 3.6 7.9 2.2 2.7 1 1 1 2 2 2 0 Spectrin repeat CP12 PF02672.10 KOS15349.1 - 8.5 6.9 9.1 2.7 8.5 2.7 2.5 2 0 0 2 2 2 0 CP12 domain Miro PF08477.8 KOS15350.1 - 9.7e-36 122.8 0.0 2e-18 67.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 KOS15350.1 - 2.7e-32 111.4 0.0 2e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 KOS15350.1 - 1.5e-25 88.2 3.3 2.1e-25 87.7 0.1 2.5 3 0 0 3 3 2 1 EF hand associated EF_assoc_2 PF08356.7 KOS15350.1 - 6.6e-25 86.7 0.0 1.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 EF hand associated AAA_22 PF13401.1 KOS15350.1 - 4.3e-08 33.3 0.0 0.0022 18.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain EF-hand_7 PF13499.1 KOS15350.1 - 2.6e-07 30.6 0.4 0.0045 17.0 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KOS15350.1 - 4.4e-07 29.2 2.3 0.00047 19.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.18 KOS15350.1 - 3.9e-06 26.7 0.0 0.018 14.9 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KOS15350.1 - 7.5e-06 26.0 1.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SRPRB PF09439.5 KOS15350.1 - 1.5e-05 24.2 0.0 0.032 13.4 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.13 KOS15350.1 - 2.3e-05 24.0 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KOS15350.1 - 3.9e-05 23.1 0.8 0.052 12.9 0.0 3.6 2 2 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KOS15350.1 - 5.7e-05 22.8 0.1 0.079 12.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain EF-hand_1 PF00036.27 KOS15350.1 - 5.9e-05 22.0 0.9 0.033 13.5 0.0 2.5 2 0 0 2 2 2 1 EF hand Arf PF00025.16 KOS15350.1 - 6.6e-05 22.2 0.0 0.0091 15.2 0.0 2.9 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.1 KOS15350.1 - 8.5e-05 22.2 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain EF-hand_8 PF13833.1 KOS15350.1 - 0.00036 20.0 1.6 0.23 11.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair AAA_10 PF12846.2 KOS15350.1 - 0.00074 19.0 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KOS15350.1 - 0.0011 18.2 0.1 0.041 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 KOS15350.1 - 0.0014 18.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KOS15350.1 - 0.0018 18.5 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 KOS15350.1 - 0.002 18.4 0.0 3.1 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS15350.1 - 0.0025 17.5 0.1 0.071 12.8 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KOS15350.1 - 0.0036 16.7 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.9 KOS15350.1 - 0.0044 16.7 0.2 3.2 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) EF-hand_10 PF14788.1 KOS15350.1 - 0.0056 16.3 0.4 0.47 10.1 0.1 2.3 2 0 0 2 2 2 1 EF hand AAA_25 PF13481.1 KOS15350.1 - 0.0058 16.0 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KOS15350.1 - 0.0068 16.2 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 KOS15350.1 - 0.0071 16.3 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS15350.1 - 0.0074 15.7 0.1 2.4 7.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KOS15350.1 - 0.009 15.8 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KOS15350.1 - 0.013 15.0 0.2 27 4.2 0.0 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein SPARC_Ca_bdg PF10591.4 KOS15350.1 - 0.015 15.3 0.0 11 6.0 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA PF00004.24 KOS15350.1 - 0.023 14.8 0.3 3.3 7.9 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KOS15350.1 - 0.029 13.8 0.0 2.5 7.5 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 KOS15350.1 - 0.046 12.8 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 1 0 AIG1 family Septin PF00735.13 KOS15350.1 - 0.053 12.5 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_5 PF13202.1 KOS15350.1 - 0.054 12.8 1.6 0.3 10.5 0.1 2.3 2 0 0 2 2 2 0 EF hand Arch_ATPase PF01637.13 KOS15350.1 - 0.056 13.1 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 KOS15350.1 - 0.063 12.2 0.0 0.75 8.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KOS15350.1 - 0.071 12.1 0.1 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KOS15350.1 - 0.11 12.6 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 KOS15350.1 - 0.12 11.2 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.4 KOS15350.1 - 0.14 11.0 0.0 4.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ribosomal_L6e PF01159.14 KOS15351.1 - 2.8e-37 127.2 0.2 4.4e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 KOS15351.1 - 0.0043 16.8 0.3 0.0043 16.8 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain DAHP_synth_2 PF01474.11 KOS15352.1 - 0.003 16.0 0.7 0.0031 15.9 0.5 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Hamartin PF04388.7 KOS15355.1 - 3.7e-06 25.9 23.9 0.00052 18.8 5.3 2.6 2 1 0 2 2 2 2 Hamartin protein IncA PF04156.9 KOS15355.1 - 0.041 13.4 31.5 0.66 9.5 4.7 2.6 1 1 0 2 2 2 0 IncA protein Filament PF00038.16 KOS15355.1 - 0.15 11.5 21.8 2.6 7.4 10.2 2.6 1 1 0 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 KOS15355.1 - 0.19 10.9 3.6 0.43 9.6 0.1 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KOS15355.1 - 0.5 10.7 14.4 4.8 7.5 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KOS15355.1 - 0.54 10.0 19.4 0.55 10.0 0.8 4.8 4 1 0 4 4 4 0 Prefoldin subunit GAS PF13851.1 KOS15355.1 - 1.7 7.7 26.8 0.71 9.0 5.6 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KOS15355.1 - 2.3 8.0 6.2 9.3 6.0 1.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KOS15355.1 - 4 7.2 6.5 4.1 7.2 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 KOS15355.1 - 4.7 6.0 17.0 3.9 6.3 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.3 KOS15355.1 - 4.9 7.0 34.0 0.83 9.5 9.3 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding YlqD PF11068.3 KOS15355.1 - 5.8 6.9 18.8 0.53 10.3 6.9 2.6 2 0 0 2 2 2 0 YlqD protein CtIP_N PF10482.4 KOS15355.1 - 6.5 6.5 17.2 0.25 11.1 0.3 3.4 3 1 1 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain Seryl_tRNA_N PF02403.17 KOS15355.1 - 7.4 6.6 17.6 1.5 8.8 1.8 4.0 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain POT1 PF02765.12 KOS15357.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 NUDIX PF00293.23 KOS15358.1 - 3.4e-12 46.1 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.18 KOS15359.1 - 2.2e-14 53.2 0.5 4.8e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS15359.1 - 0.0023 18.0 0.1 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF177 PF02620.12 KOS15359.1 - 0.11 12.5 3.8 0.2 11.7 2.6 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 SURF2 PF05477.6 KOS15359.1 - 1.1 8.3 5.9 1.4 7.9 4.1 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ODC_AZ PF02100.12 KOS15361.1 - 6.9e-15 54.4 0.0 2.2e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme VPR PF00522.13 KOS15361.1 - 0.047 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 VPR/VPX protein AIRC PF00731.15 KOS15363.1 - 1.6e-63 212.4 2.3 4.2e-63 211.1 1.6 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KOS15363.1 - 1.5e-55 187.2 0.0 2.4e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GMC_oxred_N PF00732.14 KOS15363.1 - 2.9e-43 148.1 0.0 4.6e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS15363.1 - 1.7e-36 125.6 0.1 1e-35 123.1 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase ATP-grasp_4 PF13535.1 KOS15363.1 - 5.4e-14 52.3 0.1 2e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain DAO PF01266.19 KOS15363.1 - 1.6e-06 27.2 0.4 0.00033 19.6 0.4 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KOS15363.1 - 0.0012 18.7 0.3 0.0092 15.8 0.1 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS15363.1 - 0.0013 18.6 0.3 0.005 16.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dala_Dala_lig_C PF07478.8 KOS15363.1 - 0.0017 17.7 0.0 0.0058 16.0 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KOS15363.1 - 0.0017 17.1 0.0 0.043 12.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Lycopene_cycl PF05834.7 KOS15363.1 - 0.0019 17.1 0.3 0.0034 16.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KOS15363.1 - 0.0032 16.3 12.7 0.022 13.6 1.1 3.2 3 1 1 4 4 3 2 FAD binding domain Pyr_redox PF00070.22 KOS15363.1 - 0.032 14.6 1.3 2.9 8.3 0.2 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CoA_binding_2 PF13380.1 KOS15363.1 - 0.041 14.0 0.1 17 5.6 0.0 3.0 1 1 1 2 2 2 0 CoA binding domain 3HCDH_N PF02737.13 KOS15363.1 - 0.13 11.8 1.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 KOS15363.1 - 0.13 11.4 0.2 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 KOS15363.1 - 0.17 11.0 1.2 0.42 9.7 0.1 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KOS15363.1 - 0.49 8.7 0.8 1.2 7.5 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein DUF3684 PF12449.3 KOS15364.1 - 0 1089.5 0.0 0 1089.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c PF02518.21 KOS15364.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F_actin_cap_B PF01115.12 KOS15365.1 - 9.8e-92 306.5 0.0 1.1e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Glycoamylase PF10091.4 KOS15365.1 - 0.049 12.7 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative glucoamylase BAR_2 PF10455.4 KOS15366.1 - 2e-46 158.1 0.9 4.3e-46 157.1 0.6 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KOS15366.1 - 4.3e-15 55.8 7.5 8.3e-14 51.6 5.2 2.0 1 1 0 1 1 1 1 BAR domain KapB PF08810.5 KOS15366.1 - 0.00021 21.3 4.0 0.016 15.2 0.2 2.9 2 1 1 3 3 3 1 Kinase associated protein B STAT_alpha PF01017.15 KOS15366.1 - 0.13 11.9 6.7 1 9.0 0.2 2.8 2 1 0 2 2 2 0 STAT protein, all-alpha domain MCPsignal PF00015.16 KOS15366.1 - 0.13 11.7 5.3 0.44 10.0 1.6 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Seryl_tRNA_N PF02403.17 KOS15366.1 - 0.15 12.0 6.8 0.66 10.0 0.0 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KOS15366.1 - 0.3 10.0 7.7 4 6.3 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 T4SS PF07996.6 KOS15366.1 - 0.33 10.7 5.7 6.9 6.4 0.5 2.8 2 1 0 2 2 2 0 Type IV secretion system proteins GAS PF13851.1 KOS15366.1 - 0.45 9.6 10.1 0.18 10.9 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.1 KOS15366.1 - 0.48 10.4 9.0 2 8.4 0.5 3.2 3 1 0 3 3 3 0 Up-regulated During Septation Tape_meas_lam_C PF09718.5 KOS15366.1 - 0.52 10.2 2.3 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zf-C4H2 PF10146.4 KOS15366.1 - 0.58 10.1 7.7 0.093 12.7 0.6 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein HSCB_C PF07743.8 KOS15366.1 - 0.69 10.4 5.9 2.9 8.3 0.6 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain bZIP_1 PF00170.16 KOS15366.1 - 0.71 9.8 3.9 0.74 9.8 0.0 2.8 3 0 0 3 3 3 0 bZIP transcription factor IncA PF04156.9 KOS15366.1 - 0.88 9.1 8.3 1 8.9 0.1 2.2 2 0 0 2 2 2 0 IncA protein PilO PF04350.8 KOS15366.1 - 1.3 8.8 8.9 19 5.1 0.2 3.3 3 0 0 3 3 3 0 Pilus assembly protein, PilO Acyl-CoA_dh_C PF12806.2 KOS15366.1 - 1.4 8.7 4.6 15 5.4 0.1 2.9 2 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF16 PF01519.11 KOS15366.1 - 6.2 7.1 7.2 7.9 6.7 1.5 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 Mnd1 PF03962.10 KOS15366.1 - 8.3 6.0 10.3 2.4 7.7 0.2 2.4 2 1 0 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 KOS15366.1 - 8.8 6.8 10.7 53 4.3 0.1 4.0 2 2 2 4 4 4 0 Syntaxin 6, N-terminal BRO1 PF03097.13 KOS15367.1 - 4.6e-97 325.1 5.8 4.6e-97 325.1 4.0 2.2 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KOS15367.1 - 2.6e-49 167.8 9.0 2.6e-49 167.8 6.3 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CBFD_NFYB_HMF PF00808.18 KOS15368.1 - 1.3e-17 63.5 0.3 2.5e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS15368.1 - 8.9e-08 32.1 0.4 4.4e-07 29.9 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 LRR_4 PF12799.2 KOS15369.1 - 3.3e-39 131.8 24.4 8.4e-09 34.8 1.0 7.0 3 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS15369.1 - 6e-23 80.3 25.1 1.6e-08 34.1 0.3 5.7 3 1 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 KOS15369.1 - 2.5e-15 54.1 26.2 0.046 13.7 0.2 10.6 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 KOS15369.1 - 1.3e-13 49.4 20.1 0.53 10.5 0.0 10.0 7 3 3 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.1 KOS15369.1 - 9.3e-12 44.8 5.2 6.2e-07 29.1 0.3 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 KOS15369.1 - 8.2e-11 40.2 23.2 2 8.9 0.0 10.1 9 1 0 9 9 9 5 Leucine rich repeat LRR_3 PF07725.7 KOS15369.1 - 6.7 6.6 15.5 27 4.7 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat CBFD_NFYB_HMF PF00808.18 KOS15370.1 - 3.3e-25 87.9 0.0 4.7e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KOS15370.1 - 5.2e-05 23.2 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Daxx PF03344.10 KOS15370.1 - 0.0022 16.5 1.1 0.0034 15.9 0.8 1.3 1 0 0 1 1 1 1 Daxx Family Cwf_Cwc_15 PF04889.7 KOS15370.1 - 4.1 7.0 7.8 5.4 6.6 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HisG PF01634.13 KOS15371.1 - 7.4e-51 171.9 0.0 1.1e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KOS15371.1 - 7e-27 93.1 0.1 1.2e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KOS15371.1 - 0.00055 19.5 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KOS15371.1 - 0.037 13.2 0.0 0.11 11.7 0.0 1.8 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 zf-Tim10_DDP PF02953.10 KOS15372.1 - 1.4e-19 69.1 0.5 1.9e-19 68.7 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KOS15372.1 - 0.11 11.9 0.9 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Chitin_synth_2 PF03142.10 KOS15373.1 - 3e-234 778.3 0.0 4.2e-234 777.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KOS15373.1 - 3e-87 293.3 0.0 3.4e-74 250.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 KOS15373.1 - 2.8e-18 65.5 0.0 4.6e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KOS15373.1 - 1.4e-15 57.7 0.5 1.1e-10 41.6 0.0 3.5 3 0 0 3 3 3 2 Glycosyltransferase like family 2 DEK_C PF08766.6 KOS15373.1 - 4.8e-13 48.6 0.1 9.4e-12 44.5 0.0 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 KOS15373.1 - 1.4e-10 41.1 5.4 1.4e-10 41.1 3.7 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KOS15373.1 - 7.5e-07 28.9 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KOS15373.1 - 0.00026 20.2 0.0 0.00071 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Kinesin PF00225.18 KOS15373.1 - 0.39 9.3 0.0 0.73 8.4 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain Proteasome PF00227.21 KOS15374.1 - 2.5e-40 137.7 0.0 2.8e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ldh_1_N PF00056.18 KOS15375.1 - 5.8e-45 152.5 0.0 8.3e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KOS15375.1 - 1.3e-40 139.0 0.0 2.9e-40 137.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KOS15375.1 - 2.4e-05 23.2 0.0 3.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KOS15375.1 - 0.0033 16.4 0.5 0.029 13.4 0.0 2.5 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 KOS15375.1 - 0.011 16.0 0.1 0.11 12.7 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 KOS15375.1 - 0.16 11.2 0.0 0.46 9.7 0.1 1.7 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Ferrochelatase PF00762.14 KOS15376.1 - 1.2e-103 346.3 0.0 1.4e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase SAGA-Tad1 PF12767.2 KOS15377.1 - 1.1e-40 139.8 0.3 1.1e-40 139.8 0.2 1.8 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit bZIP_1 PF00170.16 KOS15378.1 - 7.9e-07 28.9 8.0 1.8e-06 27.8 3.3 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KOS15378.1 - 0.27 11.0 9.9 1.4 8.8 5.8 2.4 1 1 1 2 2 2 0 Basic region leucine zipper FAD-oxidase_C PF02913.14 KOS15379.1 - 0.0084 15.4 0.9 0.01 15.1 0.1 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain Bromo_TP PF07524.8 KOS15380.1 - 1.7e-10 40.4 0.1 2.7e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KOS15380.1 - 5e-07 29.6 0.1 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term DUF2924 PF11149.3 KOS15380.1 - 0.1 12.5 0.7 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Bromodomain PF00439.20 KOS15381.1 - 6.3e-11 42.0 0.0 2.7e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BAH PF01426.13 KOS15381.1 - 5.9e-08 32.4 0.0 8.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 BAH domain ABC_ATPase PF09818.4 KOS15382.1 - 5.7e-139 463.5 0.0 2.8e-138 461.2 0.0 1.8 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 KOS15382.1 - 0.035 13.4 0.0 0.09 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNase_PH PF01138.16 KOS15383.1 - 6.2e-30 104.2 0.0 8.8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DSPc PF00782.15 KOS15384.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KOS15384.1 - 0.00024 21.1 0.0 0.0008 19.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KOS15384.1 - 0.0032 16.8 0.0 0.0063 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KOS15384.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Aminotran_3 PF00202.16 KOS15385.1 - 5.5e-104 347.6 0.0 6.5e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KOS15385.1 - 0.0004 19.4 0.0 0.00076 18.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KOS15385.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase rRNA_proc-arch PF13234.1 KOS15386.1 - 4.2e-81 272.0 0.0 6.2e-81 271.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KOS15386.1 - 2.5e-57 193.0 0.1 2.5e-57 193.0 0.0 2.7 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.24 KOS15386.1 - 7e-21 74.4 0.0 5.7e-20 71.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15386.1 - 7.8e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS15386.1 - 0.015 15.1 0.0 0.16 11.8 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KOS15386.1 - 0.062 12.4 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 KOS15386.1 - 0.083 11.7 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein UMP1 PF05348.6 KOS15387.1 - 7.6e-22 77.6 0.5 9.3e-22 77.3 0.4 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Y_phosphatase2 PF03162.8 KOS15388.1 - 1.2e-59 200.3 0.0 1.8e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KOS15388.1 - 1.4e-07 31.8 0.0 3.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS15388.1 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KOS15388.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Sel1 PF08238.7 KOS15389.1 - 1.6e-39 133.4 20.6 1.1e-05 25.9 0.3 8.0 8 0 0 8 8 8 7 Sel1 repeat Peptidase_S10 PF00450.17 KOS15390.1 - 1.3e-93 314.4 0.0 1.7e-93 314.0 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KOS15390.1 - 0.0027 17.6 0.0 0.015 15.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family HhH-GPD PF00730.20 KOS15391.1 - 8e-19 67.9 0.0 1.8e-18 66.7 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KOS15391.1 - 1.3e-15 56.8 0.0 3.2e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.4 KOS15391.1 - 0.0014 18.6 5.7 0.0038 17.3 3.9 1.8 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 KOS15391.1 - 0.0018 17.8 0.5 0.0064 16.1 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KOS15391.1 - 0.016 15.3 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain RabGAP-TBC PF00566.13 KOS15392.1 - 3e-47 160.8 0.0 4.8e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Histidinol_dh PF00815.15 KOS15393.1 - 1.4e-166 554.2 6.0 1.4e-165 550.9 4.2 2.0 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KOS15393.1 - 1.9e-23 81.8 0.3 3.7e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KOS15393.1 - 4e-10 39.8 0.9 9.8e-10 38.5 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KOS15393.1 - 0.071 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Toprim_3 PF13362.1 KOS15393.1 - 0.081 13.1 1.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Toprim domain EF-hand_1 PF00036.27 KOS15394.1 - 3.3e-39 129.1 11.1 6.2e-09 34.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KOS15394.1 - 1.9e-33 114.3 3.9 4e-16 58.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KOS15394.1 - 1.8e-32 110.7 8.3 2.5e-14 52.6 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KOS15394.1 - 1.3e-29 99.3 7.5 2.8e-09 36.0 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KOS15394.1 - 2.7e-29 99.1 8.2 3.1e-07 29.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KOS15394.1 - 8.5e-15 54.4 0.1 4.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KOS15394.1 - 9e-09 35.3 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KOS15394.1 - 4.3e-08 32.8 0.4 0.0055 16.4 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KOS15394.1 - 1.9e-06 27.3 0.0 0.35 10.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KOS15394.1 - 5.1e-05 23.1 0.8 0.00015 21.6 0.2 1.9 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 KOS15394.1 - 0.00043 19.7 0.3 0.00053 19.4 0.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 KOS15394.1 - 0.00087 19.0 0.6 0.67 9.6 0.1 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KOS15394.1 - 0.0095 15.5 0.4 0.16 11.5 0.3 2.8 1 1 0 1 1 1 1 Caleosin related protein DUF3349 PF11829.3 KOS15394.1 - 0.025 14.9 0.0 0.66 10.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) Fe_hyd_lg_C PF02906.9 KOS15394.1 - 0.14 11.3 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain KIP1 PF07765.7 KOS15394.1 - 0.38 10.6 1.6 12 5.8 0.0 3.2 3 1 0 4 4 4 0 KIP1-like protein INCENP_ARK-bind PF03941.10 KOS15395.1 - 1.3e-09 37.7 0.0 4.2e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SH3_9 PF14604.1 KOS15396.1 - 1.7e-13 49.9 0.2 3.1e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KOS15396.1 - 6.1e-13 48.8 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 KOS15396.1 - 3.4e-12 45.5 0.1 6.5e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 KOS15396.1 - 8e-10 38.4 0.0 1.3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KOS15396.1 - 9.9e-08 31.3 0.1 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 KOS15396.1 - 8.7e-06 25.8 0.1 1.5e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KOS15396.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 KOS15396.1 - 0.02 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_11 PF15413.1 KOS15396.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 KOS15396.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 PH domain DUF2435 PF10363.4 KOS15397.1 - 3e-26 91.1 0.2 1.5e-25 88.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KOS15397.1 - 0.0052 16.2 1.1 0.012 15.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) ADH_zinc_N_2 PF13602.1 KOS15398.1 - 2e-08 35.2 0.0 5.7e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KOS15398.1 - 0.00013 21.7 0.1 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KOS15398.1 - 0.0084 15.6 0.1 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Erv26 PF04148.8 KOS15399.1 - 1.3e-06 27.9 3.0 2.9e-06 26.8 2.1 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Robl_LC7 PF03259.12 KOS15399.1 - 0.04 13.4 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain DUF2842 PF11003.3 KOS15399.1 - 1.2 9.1 10.3 0.41 10.5 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2842) DnaJ PF00226.26 KOS15400.1 - 7.9e-21 73.5 0.9 1.4e-20 72.8 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain PX PF00787.19 KOS15401.1 - 1.5e-14 53.7 0.2 2.9e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 KOS15401.1 - 1.1e-08 34.6 9.1 1.1e-08 34.6 6.3 1.6 2 0 0 2 2 2 1 SNARE domain DUF1664 PF07889.7 KOS15401.1 - 0.081 12.7 2.0 0.14 11.9 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 KOS15401.1 - 0.13 11.8 8.5 1.2 8.6 4.1 2.1 2 0 0 2 2 2 0 IncA protein Snapin_Pallidin PF14712.1 KOS15401.1 - 0.27 11.5 7.4 1.9 8.8 4.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 KOS15401.1 - 0.92 7.2 2.9 0.96 7.2 1.4 1.2 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TBCC PF07986.7 KOS15402.1 - 1.8e-13 49.9 0.6 4.6e-13 48.6 0.2 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C RFamide_26RFa PF11109.3 KOS15402.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 BBP1_C PF15272.1 KOS15402.1 - 0.13 11.8 0.3 0.18 11.3 0.2 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PRANC PF09372.5 KOS15402.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 PRANC domain CTP_transf_2 PF01467.21 KOS15403.1 - 0.096 12.7 0.0 0.36 10.8 0.0 1.9 1 1 0 1 1 1 0 Cytidylyltransferase Abhydrolase_5 PF12695.2 KOS15404.1 - 2.2e-07 30.7 0.0 3.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS15404.1 - 1.6e-06 28.2 3.3 2.2e-06 27.7 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KOS15404.1 - 0.0004 20.0 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KOS15404.1 - 0.0087 15.6 0.1 0.038 13.6 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Esterase PF00756.15 KOS15404.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 KOS15404.1 - 0.042 13.1 0.1 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KOS15404.1 - 0.075 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KOS15404.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 KOS15404.1 - 0.098 12.8 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PP2C PF00481.16 KOS15405.1 - 5.6e-77 258.5 0.0 8.1e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BCS1_N PF08740.6 KOS15406.1 - 2.3e-51 174.1 0.1 3.1e-51 173.6 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KOS15406.1 - 5e-17 62.3 0.0 8.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KOS15406.1 - 7.8e-05 23.4 0.0 0.00018 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS15406.1 - 0.0015 17.9 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS15406.1 - 0.0033 17.3 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS15406.1 - 0.023 14.4 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 KOS15406.1 - 0.026 14.5 3.8 0.027 14.4 0.2 2.8 2 1 1 3 3 2 0 AAA ATPase domain AAA_28 PF13521.1 KOS15406.1 - 0.028 14.3 0.0 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KOS15406.1 - 0.065 13.5 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KOS15406.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 KOS15406.1 - 0.083 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 KOS15406.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS15406.1 - 0.098 12.1 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KOS15406.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 KOS15406.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Alpha_GJ PF03229.8 KOS15407.1 - 5.3 7.3 7.7 0.79 10.0 1.5 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J KH_1 PF00013.24 KOS15408.1 - 2.2e-26 91.2 0.0 9.6e-10 37.9 0.1 6.3 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 KOS15408.1 - 1.1e-17 63.2 0.5 3e-07 29.9 0.1 4.5 4 0 0 4 4 4 3 KH domain tRNA_U5-meth_tr PF05958.6 KOS15409.1 - 5.3e-20 71.4 0.2 1.3e-18 66.7 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KOS15409.1 - 3.6e-10 39.6 0.0 7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KOS15409.1 - 3.3e-06 26.7 0.0 7.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KOS15409.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS15409.1 - 8.8e-05 21.9 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KOS15409.1 - 9.4e-05 22.9 0.1 0.00026 21.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 KOS15409.1 - 0.002 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRAM PF01938.15 KOS15409.1 - 0.0024 17.5 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_11 PF08241.7 KOS15409.1 - 0.0026 18.1 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KOS15409.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TPMT PF05724.6 KOS15409.1 - 0.0098 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Met_10 PF02475.11 KOS15409.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 KOS15409.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Proteasome PF00227.21 KOS15410.1 - 8.1e-52 175.2 0.0 1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KOS15410.1 - 1.7e-11 43.1 0.1 4.1e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal LSM PF01423.17 KOS15411.1 - 4.6e-12 45.3 0.0 6.7e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS15411.1 - 0.00021 21.1 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RNA_pol_Rpb5_C PF01191.14 KOS15412.1 - 1.2e-34 117.6 0.1 2.6e-34 116.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KOS15412.1 - 3.7e-29 100.9 2.3 5.6e-29 100.4 0.8 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KOS15412.1 - 0.00015 21.5 0.1 0.00026 20.7 0.1 1.4 1 1 0 1 1 1 1 Restriction endonuclease SH3BGR PF04908.10 KOS15413.1 - 3.2e-06 26.9 0.0 9.9e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Ion_trans PF00520.26 KOS15414.1 - 3e-98 326.9 70.4 1.5e-32 112.5 4.3 5.1 5 0 0 5 5 5 4 Ion transport protein GDA1_CD39 PF01150.12 KOS15415.1 - 6.2e-95 318.2 0.0 8.7e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KOS15415.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SCO1-SenC PF02630.9 KOS15416.1 - 1.1e-55 187.9 0.0 1.5e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KOS15416.1 - 0.0085 15.7 0.0 0.046 13.3 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family NMT1_2 PF13379.1 KOS15417.1 - 0.0041 16.5 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family PRP1_N PF06424.7 KOS15418.1 - 5.4e-50 169.1 6.8 1.4e-49 167.8 4.7 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KOS15418.1 - 1.5e-20 71.7 55.3 0.015 15.8 0.5 15.4 7 3 9 16 16 16 11 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15418.1 - 3e-13 50.0 51.5 3.1e-07 30.9 1.0 9.6 10 2 1 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15418.1 - 2.9e-10 40.3 30.2 2.3 8.6 0.1 10.2 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15418.1 - 2.6e-06 26.8 6.7 0.94 9.5 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15418.1 - 7.8e-06 26.0 7.7 0.26 11.8 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS15418.1 - 3.9e-05 23.2 9.1 0.16 11.6 0.1 7.5 8 2 0 8 8 8 1 TPR repeat TPR_12 PF13424.1 KOS15418.1 - 0.00052 19.9 21.2 0.37 10.7 0.3 7.4 8 1 0 8 8 8 3 Tetratricopeptide repeat DEAD PF00270.24 KOS15419.1 - 8.3e-22 77.4 0.0 1.3e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KOS15419.1 - 1.4e-12 48.0 0.4 3.3e-12 46.8 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KOS15419.1 - 1.3e-11 44.1 0.2 7e-11 41.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KOS15419.1 - 1.3e-07 31.7 0.0 2.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like UreE_C PF05194.7 KOS15419.1 - 0.016 15.3 0.1 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KOS15420.1 - 1e-26 93.8 1.4 1.8e-26 93.0 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KOS15420.1 - 3.8e-18 65.0 0.0 7.8e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KOS15420.1 - 2.3e-16 59.0 0.4 5e-16 57.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KOS15420.1 - 3.5e-13 50.1 0.0 1e-12 48.6 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KOS15420.1 - 0.012 15.8 0.3 0.023 14.9 0.2 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_28 PF02636.12 KOS15421.1 - 2.6e-68 230.1 0.0 3.5e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase OB_NTP_bind PF07717.11 KOS15422.1 - 6.1e-16 58.2 0.0 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS15422.1 - 1.1e-14 54.2 0.1 3.5e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS15422.1 - 5.3e-11 42.2 0.0 4.2e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS15422.1 - 2.2e-07 30.5 0.6 7.6e-07 28.7 0.4 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS15422.1 - 3.1e-06 27.1 0.0 2.1e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS15422.1 - 0.00021 21.4 0.8 0.0022 18.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 KOS15422.1 - 0.0052 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 KOS15422.1 - 0.0094 14.8 0.2 0.023 13.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KOS15422.1 - 0.016 14.6 0.0 0.084 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KOS15422.1 - 0.017 15.3 0.0 0.26 11.6 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 KOS15422.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KOS15422.1 - 0.053 13.5 1.0 0.74 9.7 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 KOS15422.1 - 0.063 12.5 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KOS15422.1 - 0.092 12.5 1.8 0.15 11.7 0.2 2.3 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KOS15422.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 HLH PF00010.21 KOS15423.1 - 7.1e-17 60.8 0.8 1.6e-16 59.7 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4079 PF13301.1 KOS15423.1 - 0.14 12.1 5.5 0.067 13.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) BAF1_ABF1 PF04684.8 KOS15423.1 - 0.23 10.2 0.1 0.34 9.6 0.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor YajC PF02699.10 KOS15423.1 - 0.34 10.6 0.3 0.64 9.7 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Malic_M PF03949.10 KOS15424.1 - 1.8e-83 280.0 0.0 2.4e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KOS15424.1 - 2.9e-67 225.7 0.0 4.7e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain zf-CCCH PF00642.19 KOS15425.1 - 2.7e-05 23.7 1.3 2.7e-05 23.7 0.9 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 KOS15425.1 - 0.019 14.6 1.0 4.1 7.0 0.2 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-CCCH_2 PF14608.1 KOS15425.1 - 0.69 10.0 11.7 3.1 7.9 0.2 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Topoisom_I_N PF02919.10 KOS15426.1 - 2e-82 275.6 0.1 2e-82 275.6 0.1 2.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KOS15426.1 - 2.7e-62 209.9 0.2 5.8e-62 208.8 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KOS15426.1 - 5.5e-17 61.1 0.9 1.4e-13 50.2 0.1 2.8 2 0 0 2 2 2 2 C-terminal topoisomerase domain Peptidase_M20 PF01546.23 KOS15427.1 - 2.4e-25 89.1 0.1 1.5e-24 86.5 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KOS15427.1 - 4.2e-17 61.3 8.3 0.00023 20.8 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 KOS15427.1 - 5.2e-09 35.8 0.0 9.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 KOS15427.1 - 0.0024 16.1 0.4 0.022 12.9 0.0 2.5 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KOS15427.1 - 0.023 13.4 0.0 2.4 6.8 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.1 KOS15427.1 - 0.033 14.4 0.2 8.8 6.7 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain BBS2_Mid PF14783.1 KOS15427.1 - 0.096 12.4 0.0 0.82 9.4 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.9 KOS15427.1 - 0.45 9.2 0.0 0.89 8.2 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Cornichon PF03311.9 KOS15428.1 - 1.2e-45 154.7 7.7 1.3e-45 154.6 5.3 1.0 1 0 0 1 1 1 1 Cornichon protein Mito_carr PF00153.22 KOS15429.1 - 4.6e-58 192.9 2.4 2.8e-20 71.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 KOS15430.1 - 7.5e-48 160.0 18.1 5.1e-17 61.2 1.0 6.7 3 3 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 KOS15430.1 - 3.3e-36 121.4 16.8 1.9e-06 27.1 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15430.1 - 2.8e-34 114.2 15.3 0.00017 21.2 0.0 10.4 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15430.1 - 6.1e-26 90.4 14.3 1.1e-06 29.1 0.2 6.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15430.1 - 4e-25 87.5 19.2 4.6e-06 26.4 0.0 6.7 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15430.1 - 2.9e-19 67.3 10.2 0.00089 18.8 0.0 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15430.1 - 2e-17 61.8 5.7 6.3e-05 22.8 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15430.1 - 4.8e-14 51.5 15.2 0.0047 17.4 0.0 9.9 5 4 6 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15430.1 - 2.7e-10 40.4 9.3 0.025 14.9 0.1 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS15430.1 - 2.8e-10 39.2 9.8 0.99 9.3 0.0 8.3 8 1 1 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS15430.1 - 5.8e-10 39.1 7.4 0.02 15.0 0.0 4.5 2 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KOS15430.1 - 6.1e-09 35.6 4.8 0.00014 21.6 0.0 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KOS15430.1 - 5.8e-06 25.5 14.9 0.00045 19.3 2.7 4.5 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15430.1 - 0.00018 21.7 15.6 5.3 7.7 0.0 8.7 9 1 1 10 10 9 1 Tetratricopeptide repeat NARP1 PF12569.3 KOS15430.1 - 0.00095 18.0 0.3 0.02 13.7 0.1 4.1 2 2 3 5 5 5 2 NMDA receptor-regulated protein 1 ALS2CR8 PF15299.1 KOS15430.1 - 0.003 17.1 0.6 0.0061 16.1 0.4 1.4 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SHNi-TPR PF10516.4 KOS15430.1 - 0.0043 16.2 4.9 14 4.9 0.0 5.5 5 0 0 5 5 5 0 SHNi-TPR Sox_N PF12444.3 KOS15430.1 - 0.1 13.7 6.5 0.32 12.1 4.5 1.8 1 0 0 1 1 1 0 Sox developmental protein N terminal Apc5 PF12862.2 KOS15430.1 - 0.22 11.3 3.6 1.2 9.0 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 Ribosomal_L13 PF00572.13 KOS15431.1 - 3.5e-50 169.3 0.1 4.1e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Snf7 PF03357.16 KOS15432.1 - 2.7e-05 23.6 7.4 2.7e-05 23.6 5.1 2.3 1 1 1 2 2 2 2 Snf7 HeLo PF14479.1 KOS15432.1 - 0.079 12.6 3.3 0.22 11.2 2.3 1.7 1 1 0 1 1 1 0 Prion-inhibition and propagation SMC_N PF02463.14 KOS15433.1 - 1.7e-18 66.7 0.0 3.5e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS15433.1 - 4.9e-12 46.6 0.0 4.9e-12 46.6 0.0 4.4 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KOS15433.1 - 2.4e-05 24.4 0.0 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KOS15433.1 - 0.0022 17.4 0.0 0.0095 15.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KOS15433.1 - 0.013 16.2 3.2 0.024 15.4 0.0 3.2 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KOS15433.1 - 0.033 13.9 0.3 0.23 11.2 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 KOS15433.1 - 0.084 13.1 0.0 0.084 13.1 0.0 4.1 3 2 0 3 3 3 0 ABC transporter DivIC PF04977.10 KOS15433.1 - 0.21 11.0 0.0 0.21 11.0 0.0 6.9 5 2 2 7 7 7 0 Septum formation initiator AAA_22 PF13401.1 KOS15433.1 - 0.84 9.7 0.0 0.84 9.7 0.0 3.5 4 1 0 4 4 4 0 AAA domain AAA PF00004.24 KOS15433.1 - 1.9 8.6 5.8 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CRAL_TRIO PF00650.15 KOS15434.1 - 1e-25 90.0 0.0 1.4e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS15434.1 - 5.1e-07 29.7 0.7 1.5e-06 28.2 0.5 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-RING_2 PF13639.1 KOS15435.1 - 1.5e-14 53.5 9.6 2.3e-14 52.9 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KOS15435.1 - 3.3e-09 36.7 5.2 5.6e-09 35.9 3.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KOS15435.1 - 1e-07 31.4 8.1 1.6e-07 30.8 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15435.1 - 9.5e-07 28.7 7.8 1.5e-06 28.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS15435.1 - 2.8e-06 26.9 6.3 4.7e-06 26.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS15435.1 - 3.3e-06 26.7 7.4 5e-06 26.1 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KOS15435.1 - 7.7e-05 22.4 4.1 0.00013 21.6 2.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 KOS15435.1 - 0.034 14.1 2.4 0.06 13.3 1.7 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 KOS15435.1 - 0.095 12.7 9.5 0.15 12.0 6.6 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KOS15435.1 - 0.19 11.3 7.8 0.36 10.4 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KOS15435.1 - 0.59 10.2 11.2 0.95 9.5 7.7 1.3 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KOS15435.1 - 1.7 8.6 7.9 3.5 7.6 5.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KOS15435.1 - 4.7 7.1 6.6 22 5.0 4.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING MDM31_MDM32 PF08118.6 KOS15436.1 - 1.9e-115 386.1 0.3 7.3e-60 202.8 0.0 3.0 3 0 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins Pex2_Pex12 PF04757.9 KOS15437.1 - 2.1e-30 105.8 5.4 3.1e-30 105.3 3.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KOS15437.1 - 2.2e-10 40.2 7.5 3.6e-10 39.5 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS15437.1 - 5.9e-10 38.7 5.7 8.8e-10 38.1 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KOS15437.1 - 7.1e-09 35.5 6.6 1.2e-08 34.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15437.1 - 4.4e-08 32.6 6.4 7.1e-08 31.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS15437.1 - 4.6e-08 32.5 8.3 7.6e-08 31.9 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KOS15437.1 - 1.4e-07 31.5 3.5 2.4e-07 30.7 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KOS15437.1 - 3.9e-05 23.4 3.7 3.9e-05 23.4 2.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KOS15437.1 - 0.0002 20.9 5.4 0.00049 19.7 3.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KOS15437.1 - 0.002 17.6 7.0 0.0032 17.0 4.8 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KOS15437.1 - 0.002 17.9 4.1 0.0039 16.9 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 KOS15437.1 - 0.0036 16.5 1.1 0.0066 15.6 0.8 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 KOS15437.1 - 0.014 15.1 3.8 0.029 14.1 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_RING PF05883.6 KOS15437.1 - 0.026 14.3 1.3 0.06 13.1 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain IBR PF01485.16 KOS15437.1 - 0.043 13.6 3.7 0.093 12.6 2.6 1.6 1 0 0 1 1 1 0 IBR domain RAB3GAP2_C PF14656.1 KOS15437.1 - 0.067 11.3 0.0 0.1 10.6 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus FERM_M PF00373.13 KOS15437.1 - 0.098 12.8 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 FERM central domain Baculo_IE-1 PF05290.6 KOS15437.1 - 0.11 12.2 0.9 0.21 11.3 0.6 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Phasin_2 PF09361.5 KOS15437.1 - 0.31 11.0 3.5 0.54 10.3 0.5 2.4 2 0 0 2 2 2 0 Phasin protein TerY-C PF15616.1 KOS15437.1 - 0.39 10.6 4.0 0.91 9.4 2.8 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain Mmp37 PF09139.6 KOS15438.1 - 1.1e-86 290.8 0.0 1.7e-86 290.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 FoP_duplication PF13865.1 KOS15439.1 - 2.6e-05 24.5 0.3 7.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 KOS15439.1 - 0.0022 17.9 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 KOS15439.1 - 0.0029 17.6 2.1 0.0064 16.5 1.5 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding RRM_5 PF13893.1 KOS15439.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS15439.1 - 0.0083 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Porin_3 PF01459.17 KOS15441.1 - 6.7e-62 209.2 0.7 7.5e-62 209.1 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin PBP1_TM PF14812.1 KOS15442.1 - 0.065 13.5 3.1 0.081 13.2 2.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KOS15442.1 - 0.14 11.6 5.3 0.14 11.6 3.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 KOS15442.1 - 0.23 10.6 5.7 0.24 10.6 3.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 KOS15442.1 - 0.28 10.3 4.1 0.3 10.2 2.8 1.0 1 0 0 1 1 1 0 NOA36 protein CENP-F_C_Rb_bdg PF10490.4 KOS15442.1 - 0.31 10.3 1.3 0.81 9.0 0.9 1.8 1 1 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Sigma70_ner PF04546.8 KOS15442.1 - 0.7 9.4 5.7 0.72 9.4 4.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 KOS15442.1 - 1.1 8.3 7.5 1.2 8.2 5.2 1.0 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KOS15442.1 - 2.1 8.6 7.7 2.6 8.3 5.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 KOS15442.1 - 4.1 5.7 6.9 4.3 5.7 4.8 1.0 1 0 0 1 1 1 0 Daxx Family Ribosomal_60s PF00428.14 KOS15442.1 - 4.6 7.6 13.0 9 6.7 9.0 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.8 KOS15442.1 - 9.1 3.9 7.7 10 3.7 5.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cullin PF00888.17 KOS15443.1 - 5.4e-174 580.0 14.5 5.4e-174 580.0 10.0 1.5 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KOS15443.1 - 8.6e-28 95.9 4.5 1.1e-27 95.6 2.2 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain rve_3 PF13683.1 KOS15443.1 - 0.0036 16.7 0.0 0.014 14.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Penicillinase_R PF03965.11 KOS15443.1 - 0.17 11.9 3.9 1.2 9.2 0.1 4.0 3 2 0 3 3 3 0 Penicillinase repressor Peptidase_M6 PF05547.6 KOS15444.1 - 0.18 9.7 0.0 0.24 9.4 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 DUF4256 PF14066.1 KOS15445.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) PI31_Prot_C PF08577.6 KOS15446.1 - 2.4e-07 31.2 17.4 5.1e-07 30.2 12.1 1.6 1 0 0 1 1 1 1 PI31 proteasome regulator DUF1325 PF07039.6 KOS15447.1 - 1.7e-21 76.1 0.1 4.7e-12 45.6 0.0 2.2 1 1 1 2 2 2 2 SGF29 tudor-like domain Cyclin_N PF00134.18 KOS15448.1 - 4.6e-10 39.1 0.2 1e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS15448.1 - 1.2e-05 25.2 0.2 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain Lipase_3 PF01764.20 KOS15449.1 - 1.2e-19 70.3 0.0 1.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 KOS15449.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Lactamase_B PF00753.22 KOS15450.1 - 1.4e-13 50.9 3.4 7.1e-13 48.6 2.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KOS15450.1 - 3.3e-05 23.5 0.1 7.5e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain OB_NTP_bind PF07717.11 KOS15451.1 - 1.1e-29 102.5 0.0 2.1e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS15451.1 - 1.9e-27 95.2 0.1 4.9e-27 93.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS15451.1 - 1.8e-11 43.7 0.0 5.5e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KOS15451.1 - 6.1e-11 42.2 0.2 1.2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KOS15451.1 - 5.5e-05 22.7 0.1 0.00012 21.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KOS15451.1 - 0.0001 21.3 0.0 0.00023 20.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KOS15451.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KOS15451.1 - 0.0016 18.7 0.3 0.095 13.0 0.0 2.7 2 1 1 3 3 2 1 ABC transporter AAA_19 PF13245.1 KOS15451.1 - 0.0067 16.1 1.3 0.018 14.7 0.3 2.2 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KOS15451.1 - 0.013 15.5 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 KOS15451.1 - 0.046 13.3 0.1 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KOS15451.1 - 0.047 14.1 0.1 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 KOS15451.1 - 0.11 12.3 0.0 1 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KOS15451.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ThiF PF00899.16 KOS15452.1 - 3.1e-38 130.6 0.3 8.3e-38 129.2 0.1 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 KOS15452.1 - 2.3e-28 97.5 1.2 5.2e-28 96.4 0.8 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KOS15452.1 - 2.2e-18 65.3 5.7 3.8e-18 64.5 3.9 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KOS15452.1 - 1.8e-07 31.1 0.0 5.9e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 KOS15452.1 - 0.0095 16.0 0.4 0.019 15.0 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KOS15452.1 - 0.12 12.7 3.5 4.7 7.6 2.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase vATP-synt_E PF01991.13 KOS15453.1 - 4.3e-57 192.6 17.2 5e-57 192.3 11.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2762 PF10960.3 KOS15453.1 - 0.03 14.0 1.1 0.03 14.0 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) UPF0449 PF15136.1 KOS15453.1 - 0.27 11.4 6.3 0.17 12.0 2.8 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2564 PF10819.3 KOS15453.1 - 2.7 8.1 8.5 12 6.1 0.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2564) V_ATPase_I PF01496.14 KOS15453.1 - 4.3 5.0 9.8 5.3 4.7 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ank_2 PF12796.2 KOS15454.1 - 1.1e-14 54.5 2.5 2.1e-14 53.5 1.3 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS15454.1 - 6.2e-11 42.5 1.3 0.00015 22.1 0.4 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS15454.1 - 3.7e-10 39.1 2.5 0.0002 21.0 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KOS15454.1 - 9.8e-10 37.7 1.3 0.0019 18.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS15454.1 - 8.1e-09 35.4 3.9 2.3e-06 27.6 0.8 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) CMS1 PF14617.1 KOS15456.1 - 1.1e-48 165.4 1.6 1.4e-47 161.9 1.1 1.9 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit eIF3_subunit PF08597.5 KOS15456.1 - 0.063 12.8 6.7 0.085 12.4 4.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Baculo_PP31 PF05311.6 KOS15456.1 - 0.12 11.6 3.6 0.18 11.0 2.5 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1708 PF08101.6 KOS15458.1 - 5.7e-21 74.8 0.1 4.1e-14 52.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) DUF4451 PF14616.1 KOS15458.1 - 8.2e-20 70.8 1.6 1.4e-19 70.0 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) RhoGAP PF00620.22 KOS15458.1 - 0.0037 16.8 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Cnd3 PF12719.2 KOS15459.1 - 8.7e-75 251.4 3.4 8.7e-75 251.4 2.4 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KOS15459.1 - 8.6e-12 45.1 18.8 1.2e-08 35.0 0.8 5.9 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.17 KOS15459.1 - 9.6e-09 34.6 7.6 0.32 11.2 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KOS15459.1 - 8.3e-07 29.3 6.5 0.16 12.4 0.0 6.5 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 KOS15459.1 - 0.00058 19.7 3.7 2.5 7.8 0.1 4.5 3 3 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.1 KOS15459.1 - 0.0021 17.3 3.8 0.02 14.1 0.2 3.0 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Adaptin_N PF01602.15 KOS15459.1 - 0.011 14.0 2.1 0.11 10.8 0.2 2.4 2 0 0 2 2 2 0 Adaptin N terminal region DUF2435 PF10363.4 KOS15459.1 - 0.039 13.8 0.5 4.3 7.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) CENP-K PF11802.3 KOS15460.1 - 1.9e-07 30.5 3.6 1.1e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Centromere-associated protein K DUF2383 PF09537.5 KOS15460.1 - 0.021 15.0 0.3 0.04 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Mod_r PF07200.8 KOS15460.1 - 0.7 9.7 7.5 0.67 9.8 4.5 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 KOS15460.1 - 1.4 8.5 7.6 1.8 8.1 5.2 1.2 1 0 0 1 1 1 0 Mnd1 family F-box-like_2 PF13013.1 KOS15460.1 - 9 6.0 8.7 24 4.7 6.0 1.6 1 1 0 1 1 1 0 F-box-like domain DUF2416 PF10315.4 KOS15461.1 - 1.1e-12 48.0 0.3 1.4e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Zn_peptidase_2 PF04298.7 KOS15461.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Myb_DNA-binding PF00249.26 KOS15462.1 - 4.9e-18 64.9 4.0 1.2e-10 41.2 0.2 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS15462.1 - 1.1e-12 47.8 0.3 1.6e-05 24.9 0.0 4.3 3 2 1 4 4 4 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KOS15462.1 - 0.0079 16.3 3.4 0.9 9.7 0.1 3.9 3 1 1 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like RRM_6 PF14259.1 KOS15463.1 - 6.6e-08 32.4 0.0 2.2e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS15463.1 - 1e-05 25.0 0.0 3.9e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15463.1 - 6.7e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 KOS15463.1 - 0.027 13.9 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) DUF4456 PF14644.1 KOS15463.1 - 0.078 12.1 5.0 0.041 13.0 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) DUF883 PF05957.8 KOS15463.1 - 0.69 10.3 5.8 3.7 7.9 3.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CENP-B_dimeris PF09026.5 KOS15463.1 - 9.1 6.5 12.9 17 5.6 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3300 PF11737.3 KOS15464.1 - 0.93 8.7 6.8 2 7.6 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Bromodomain PF00439.20 KOS15465.1 - 2.3e-21 75.5 0.0 4.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain T2SM_b PF10741.4 KOS15465.1 - 0.086 12.4 1.6 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b RNA_pol_N PF01194.12 KOS15466.1 - 5.8e-29 99.9 0.5 6.7e-29 99.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PEPCK_ATP PF01293.15 KOS15467.1 - 2e-217 722.3 0.0 2.3e-217 722.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 KOS15467.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KOS15467.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KOS15468.1 - 6.7e-46 152.6 6.9 6.5e-09 35.3 0.0 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat eIF2A PF08662.6 KOS15468.1 - 7.7e-09 35.5 0.0 0.011 15.4 0.0 4.3 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KOS15468.1 - 9.5e-08 31.4 0.1 0.049 12.7 0.0 4.1 3 2 0 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KOS15468.1 - 0.00056 18.7 0.0 5.3 5.6 0.0 4.7 3 2 1 5 5 5 1 Nup133 N terminal like CPSF_A PF03178.10 KOS15468.1 - 0.0018 17.4 0.0 3.8 6.4 0.0 3.8 3 2 0 3 3 3 2 CPSF A subunit region IKI3 PF04762.7 KOS15468.1 - 0.0043 14.9 0.2 0.069 10.9 0.1 2.3 2 1 0 2 2 2 1 IKI3 family DUF3312 PF11768.3 KOS15468.1 - 0.026 12.7 0.1 0.087 11.0 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Diphthamide_syn PF01866.12 KOS15469.1 - 1.9e-63 214.5 0.0 1.7e-34 119.4 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Erg28 PF03694.8 KOS15470.1 - 3.3e-33 114.0 0.4 3.7e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 Erg28 like protein Abhydrolase_9_N PF15420.1 KOS15470.1 - 0.14 11.9 2.6 0.29 10.8 1.8 1.6 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Zn_clus PF00172.13 KOS15471.1 - 0.00019 21.2 9.8 0.00019 21.2 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KOS15471.1 - 0.00033 20.4 0.0 0.00087 19.0 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KOS15471.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain ATP-synt_DE_N PF02823.11 KOS15472.1 - 2e-19 69.1 0.3 2.9e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain NDUF_B12 PF08122.7 KOS15473.1 - 6e-19 67.5 1.0 6.6e-19 67.3 0.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family PGAP1 PF07819.8 KOS15474.1 - 1.3e-59 201.5 0.0 1.9e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KOS15474.1 - 3.4e-07 30.3 1.1 3.4e-07 30.3 0.8 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS15474.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KOS15474.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 KOS15474.1 - 0.1 11.6 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KOS15474.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) Sec6 PF06046.8 KOS15475.1 - 2.2e-113 379.2 0.9 3.1e-113 378.8 0.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 SSF PF00474.12 KOS15476.1 - 9e-14 50.9 28.8 1.6e-13 50.1 20.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Ribosomal_L39 PF00832.15 KOS15477.1 - 9e-21 73.0 10.0 1e-20 72.8 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein F1F0-ATPsyn_F PF10791.4 KOS15478.1 - 1.4e-27 95.7 0.1 1.7e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KOS15478.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Rad52_Rad22 PF04098.10 KOS15479.1 - 4.9e-54 182.2 0.2 1.1e-53 181.0 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein TAFII28 PF04719.9 KOS15480.1 - 1.9e-23 82.0 0.0 3e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region NPR3 PF03666.8 KOS15480.1 - 0.61 8.5 2.7 0.85 8.0 1.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BTV_NS2 PF04514.7 KOS15480.1 - 5.7 5.7 10.4 7 5.4 7.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_M48 PF01435.13 KOS15481.1 - 8.3e-40 136.7 0.0 1.7e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 KOS15481.1 - 0.011 15.4 0.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M56 PF05569.6 KOS15481.1 - 0.14 11.0 3.1 0.3 10.0 1.8 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF4044 PF13253.1 KOS15481.1 - 1.4 8.0 4.3 3.4 6.8 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Longin PF13774.1 KOS15482.1 - 2.2e-25 87.9 0.1 3.3e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KOS15482.1 - 1.5e-15 56.5 0.0 2.9e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 KOS15482.1 - 0.0065 16.2 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Ribosomal_S10 PF00338.17 KOS15483.1 - 4.8e-20 71.2 0.0 1.1e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Senescence_reg PF04520.8 KOS15483.1 - 0.047 14.1 0.4 0.09 13.2 0.3 1.4 1 0 0 1 1 1 0 Senescence regulator PRA1 PF03208.14 KOS15484.1 - 4.2e-36 123.6 2.7 4.9e-36 123.3 1.8 1.0 1 0 0 1 1 1 1 PRA1 family protein DNA_ligase_A_M PF01068.16 KOS15485.1 - 1.1e-52 178.4 0.0 1.6e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KOS15485.1 - 1.5e-52 178.0 1.8 2.3e-52 177.3 1.2 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KOS15485.1 - 1.6e-24 86.1 0.0 3.7e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KOS15485.1 - 0.0091 15.6 0.4 1.9 8.2 0.0 2.7 3 0 0 3 3 3 2 DNA ligase OB-like domain GAS2 PF02187.12 KOS15485.1 - 0.022 14.4 0.1 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain eIF-3c_N PF05470.7 KOS15485.1 - 0.1 10.6 0.1 0.14 10.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mago_nashi PF02792.9 KOS15486.1 - 5.3e-76 253.1 0.4 6e-76 252.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 KOS15486.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Ras PF00071.17 KOS15487.1 - 8.8e-55 184.5 0.0 1e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS15487.1 - 3e-18 66.4 0.0 4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS15487.1 - 1.2e-15 57.2 0.0 1.5e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KOS15487.1 - 4.6e-06 26.5 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS15487.1 - 2.5e-05 23.5 0.0 2.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS15487.1 - 4e-05 23.1 0.0 7.8e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KOS15487.1 - 0.0012 18.8 0.3 0.0074 16.2 0.0 2.1 1 1 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KOS15487.1 - 0.0019 17.3 0.5 0.016 14.3 0.0 2.3 2 1 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KOS15487.1 - 0.0029 17.7 0.0 0.0069 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 KOS15487.1 - 0.012 14.8 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 KOS15487.1 - 0.027 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KOS15487.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KOS15487.1 - 0.039 13.4 0.2 0.082 12.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KOS15487.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KOS15487.1 - 0.059 12.9 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS15487.1 - 0.096 12.1 0.0 9.8 5.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNase_P_Rpp14 PF01900.14 KOS15488.1 - 2.7e-21 75.4 0.0 4.7e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family SH3_2 PF07653.12 KOS15488.1 - 7.1e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KOS15488.1 - 0.00045 19.5 0.0 0.0093 15.3 0.0 2.3 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS15488.1 - 0.0073 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pil1 PF13805.1 KOS15489.1 - 5.3e-09 35.6 0.5 5.3e-09 35.6 0.3 2.1 2 0 0 2 2 2 1 Eisosome component PIL1 Nrap PF03813.9 KOS15490.1 - 2.7e-217 723.6 0.0 3e-217 723.4 0.0 1.0 1 0 0 1 1 1 1 Nrap protein SPA PF08616.5 KOS15491.1 - 4.3e-27 94.0 0.0 8e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 KOS15491.1 - 6.1e-16 58.7 1.2 3.2e-15 56.4 0.0 2.8 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPX PF03105.14 KOS15492.1 - 1.5e-28 100.3 0.6 1.7e-27 96.9 0.0 2.6 2 1 0 2 2 2 1 SPX domain zf-C3HC4_4 PF15227.1 KOS15492.1 - 5.5e-06 26.1 8.5 1e-05 25.3 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KOS15492.1 - 1.2e-05 24.8 8.0 2e-05 24.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15492.1 - 1.7e-05 24.3 10.2 3e-05 23.5 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15492.1 - 0.00013 21.9 11.3 0.00021 21.2 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS15492.1 - 0.00017 21.3 11.4 0.0003 20.5 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS15492.1 - 0.00038 20.1 8.1 0.00073 19.2 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KOS15492.1 - 0.0039 16.7 3.2 0.0077 15.8 2.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KOS15492.1 - 0.022 14.5 3.2 0.042 13.6 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KOS15492.1 - 0.4 10.4 7.9 1.2 8.8 5.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger GCFC PF07842.7 KOS15493.1 - 1.1e-67 228.3 12.5 1.5e-67 227.8 8.7 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KOS15493.1 - 7.3e-10 38.4 0.8 7.3e-10 38.4 0.6 1.9 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 KOS15493.1 - 0.0014 18.4 2.4 0.007 16.1 0.3 2.8 2 1 0 2 2 2 1 DExH-box splicing factor binding site DUF2029 PF09594.5 KOS15497.1 - 0.048 13.1 0.1 0.049 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) RRM_1 PF00076.17 KOS15498.1 - 3e-07 29.9 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KOS15498.1 - 0.0027 17.7 0.0 0.0074 16.3 0.0 1.8 2 0 0 2 2 2 1 PWI domain RRM_6 PF14259.1 KOS15498.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phos_pyr_kin PF08543.7 KOS15499.1 - 3.7e-74 249.0 1.7 1.6e-55 187.9 0.2 2.2 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KOS15499.1 - 1.6e-34 119.4 0.6 2.5e-34 118.9 0.4 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 KOS15499.1 - 0.0025 17.0 0.3 0.28 10.2 0.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family DUF2052 PF09747.4 KOS15500.1 - 0.03 14.2 0.1 0.054 13.4 0.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GPP34 PF05719.6 KOS15500.1 - 0.63 10.0 4.7 1.3 9.0 3.3 1.5 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Pox_A9 PF04835.7 KOS15501.1 - 0.88 9.5 6.4 0.13 12.1 0.9 2.2 2 0 0 2 2 2 0 A9 protein conserved region Cation_efflux PF01545.16 KOS15502.1 - 1.1e-14 54.2 4.1 1.1e-14 54.2 2.8 1.9 2 0 0 2 2 2 1 Cation efflux family F-box-like PF12937.2 KOS15503.1 - 0.056 13.1 1.7 0.15 11.8 0.2 2.5 3 0 0 3 3 3 0 F-box-like Xpo1 PF08389.7 KOS15504.1 - 1.1e-13 51.3 0.5 3e-12 46.6 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_C PF08767.6 KOS15504.1 - 2.7e-05 23.2 0.0 7e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 CRM1 C terminal HEAT_EZ PF13513.1 KOS15504.1 - 4.8 7.7 9.6 8.7 6.9 0.1 5.5 5 1 0 5 5 5 0 HEAT-like repeat Nbl1_Borealin_N PF10444.4 KOS15505.1 - 3.5e-08 32.6 0.2 4.7e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Apolipoprotein PF01442.13 KOS15505.1 - 0.086 12.3 1.0 0.094 12.2 0.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TOM13 PF08219.6 KOS15506.1 - 2.1e-10 40.1 1.2 2.1e-10 40.1 0.8 1.8 2 0 0 2 2 2 1 Outer membrane protein TOM13 Pex14_N PF04695.8 KOS15507.1 - 0.11 12.4 4.9 0.23 11.4 3.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 KOS15507.1 - 0.39 8.9 15.7 0.47 8.6 10.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1183 PF06682.7 KOS15507.1 - 1 8.9 16.0 1.2 8.6 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF566 PF04484.7 KOS15507.1 - 2.7 7.4 13.8 3.7 6.9 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DNA_pol_viral_N PF00242.12 KOS15507.1 - 7.8 5.4 11.0 9.5 5.1 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Apt1 PF10351.4 KOS15507.1 - 9.6 4.9 10.9 12 4.5 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2373 PF10180.4 KOS15508.1 - 2.8e-13 49.2 2.0 8.9e-08 31.5 1.9 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Rrn6 PF10214.4 KOS15508.1 - 0.65 8.0 4.1 0.88 7.5 2.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor F-actin_cap_A PF01267.12 KOS15510.1 - 4.6e-69 232.4 0.0 5.9e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit LETM1 PF07766.8 KOS15510.1 - 0.072 12.1 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein Calcipressin PF04847.7 KOS15511.1 - 1.4e-26 93.2 0.2 8.8e-26 90.6 0.1 2.1 1 1 0 1 1 1 1 Calcipressin Voldacs PF03517.8 KOS15511.1 - 2.5e-20 72.7 0.9 2.5e-20 72.7 0.6 2.1 2 1 1 3 3 3 1 Regulator of volume decrease after cellular swelling HSF_DNA-bind PF00447.12 KOS15512.1 - 1.1e-20 73.7 0.0 1.8e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HUN PF08729.5 KOS15513.1 - 4.9e-13 48.7 0.1 1.4e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 KOS15513.1 - 9e-09 35.3 0.1 1.7e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Ubinuclein conserved middle domain Mg_trans_NIPA PF05653.9 KOS15514.1 - 2.7e-93 312.2 24.0 3.6e-93 311.8 16.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KOS15514.1 - 4.4e-05 23.5 9.5 4.4e-05 23.5 6.6 4.0 3 1 2 5 5 5 1 EamA-like transporter family EmrE PF13536.1 KOS15514.1 - 0.0027 17.8 8.1 0.0027 17.8 5.6 3.3 1 1 3 4 4 4 1 Multidrug resistance efflux transporter Trm112p PF03966.11 KOS15515.1 - 2.7e-20 72.4 0.0 3.7e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.7 KOS15515.1 - 0.056 12.7 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-NADH-PPase PF09297.6 KOS15515.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.5 KOS15515.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.7 2 0 0 2 2 2 0 A2L zinc ribbon domain Pyridoxal_deC PF00282.14 KOS15516.1 - 4.1e-24 84.7 0.0 6.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KOS15516.1 - 1.2e-10 40.6 0.0 2.3e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KOS15516.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KOS15516.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase ABC_membrane_2 PF06472.10 KOS15517.1 - 1.7e-88 296.4 6.8 2.2e-88 296.0 4.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KOS15517.1 - 3.6e-20 72.6 0.0 9.5e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KOS15517.1 - 0.00083 19.7 0.6 0.0045 17.3 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KOS15517.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KOS15517.1 - 0.0094 15.1 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS15517.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KOS15517.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 KOS15517.1 - 0.096 11.3 0.4 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRP-alpha_N PF04086.8 KOS15517.1 - 2.9 7.1 13.5 5.5 6.2 9.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_1b PF00579.20 KOS15518.1 - 1.4e-63 214.7 0.0 2.2e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EMP70 PF02990.11 KOS15519.1 - 9.1e-181 601.8 0.1 1.4e-180 601.2 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1c PF00749.16 KOS15520.1 - 1.1e-101 339.6 0.0 1.5e-101 339.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KOS15520.1 - 3e-33 114.9 0.0 9.2e-32 110.0 0.0 2.3 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KOS15520.1 - 1.9e-30 105.5 0.0 3.5e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 KOS15520.1 - 3.5e-10 40.4 1.5 3.5e-10 40.4 1.0 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_60s PF00428.14 KOS15520.1 - 8.3 6.8 13.1 0.41 11.0 4.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosom_S12_S23 PF00164.20 KOS15521.1 - 6.2e-38 128.9 0.4 7e-38 128.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 T4_Gp59_C PF08994.5 KOS15521.1 - 0.047 13.8 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Brix PF04427.13 KOS15522.1 - 1.7e-38 132.2 0.0 2.1e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF0172 PF03665.8 KOS15523.1 - 2.3e-33 115.3 1.1 7.2e-33 113.7 0.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF1663 PF07909.6 KOS15523.1 - 0.088 11.3 0.0 0.098 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) Med14 PF08638.6 KOS15524.1 - 3e-39 134.3 0.0 3.5e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit MED14 Mito_carr PF00153.22 KOS15526.1 - 6.2e-10 38.6 0.1 0.0025 17.4 0.0 3.4 4 0 0 4 4 4 2 Mitochondrial carrier protein ERCC4 PF02732.10 KOS15527.1 - 3.3e-09 36.6 0.3 5.2e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain TC1 PF15063.1 KOS15527.1 - 0.082 12.4 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 AAA_16 PF13191.1 KOS15528.1 - 0.059 13.3 0.1 0.094 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain TruD PF01142.13 KOS15529.1 - 1.7e-58 198.1 0.0 9e-58 195.7 0.0 2.1 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) TPR_17 PF13431.1 KOS15530.1 - 1.4e-06 27.9 8.1 0.024 14.7 0.2 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS15530.1 - 6.3e-06 25.7 3.0 6.3e-06 25.7 2.1 5.6 7 0 0 7 7 7 2 TPR repeat TPR_2 PF07719.12 KOS15530.1 - 0.0007 19.3 2.4 0.0007 19.3 1.6 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS15530.1 - 0.0017 17.8 1.0 0.0017 17.8 0.7 4.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15530.1 - 0.0024 18.4 5.3 0.0024 18.4 3.7 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15530.1 - 0.0033 17.7 22.4 0.074 13.4 2.2 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15530.1 - 0.015 15.9 47.5 0.022 15.3 0.4 10.3 7 2 3 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15530.1 - 0.035 13.8 0.3 4.7 7.2 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15530.1 - 2.3 8.1 30.2 0.66 9.9 1.0 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Med3 PF11593.3 KOS15530.1 - 5 6.2 8.0 10 5.2 5.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pex16 PF08610.5 KOS15531.1 - 2e-73 247.3 0.7 4.9e-61 206.5 0.1 2.0 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) IMS PF00817.15 KOS15532.1 - 5.3e-46 156.1 0.2 1.6e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KOS15532.1 - 2.5e-17 62.9 0.2 5.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KOS15532.1 - 0.00077 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif Spore_YhcN_YlaJ PF09580.5 KOS15532.1 - 0.019 15.0 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PEP-utilisers_N PF05524.8 KOS15532.1 - 0.13 12.1 3.7 0.86 9.4 0.0 2.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal ox_reductase_C PF08635.5 KOS15533.1 - 1.4e-135 445.9 0.2 6.4e-70 233.1 0.0 2.3 2 0 0 2 2 2 2 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KOS15533.1 - 2.7e-39 134.3 0.0 5.8e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS15533.1 - 2.7e-06 27.1 0.0 0.002 17.9 0.0 2.9 2 0 0 2 2 2 2 Oxidoreductase family, C-terminal alpha/beta domain Chordopox_A30L PF06015.7 KOS15533.1 - 0.49 10.0 1.9 5 6.8 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus A30L protein EOS1 PF12326.3 KOS15534.1 - 6.3e-20 71.3 0.4 1.3e-19 70.2 0.3 1.6 1 1 0 1 1 1 1 N-glycosylation protein Clathrin_lg_ch PF01086.12 KOS15535.1 - 5e-32 111.6 21.5 2.2e-28 99.7 14.9 2.2 1 1 0 1 1 1 1 Clathrin light chain DUF2937 PF11157.3 KOS15535.1 - 0.2 10.9 6.2 2.7 7.3 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF501 PF04417.7 KOS15535.1 - 0.43 10.4 7.5 0.35 10.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Nucleo_P87 PF07267.6 KOS15535.1 - 0.49 9.0 7.4 0.61 8.7 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BPL_LplA_LipB PF03099.14 KOS15536.1 - 2.8e-17 62.8 0.0 6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GPP34 PF05719.6 KOS15537.1 - 1.9e-56 191.3 0.2 2.6e-56 190.9 0.2 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DEAD PF00270.24 KOS15538.1 - 1.9e-46 157.6 0.0 1.5e-44 151.5 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15538.1 - 6.3e-25 86.8 0.0 1.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KOS15538.1 - 0.00011 20.7 0.1 0.0022 16.4 0.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) Malate_synthase PF01274.17 KOS15539.1 - 2.2e-210 699.1 0.0 2.5e-210 698.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 KOS15539.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family KH_1 PF00013.24 KOS15540.1 - 6.5e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KOS15540.1 - 0.00042 19.8 0.0 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KOS15540.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 KH domain Peptidase_M16 PF00675.15 KOS15541.1 - 4.5e-43 146.5 3.5 1.1e-41 142.1 0.0 3.7 3 1 1 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KOS15541.1 - 4.5e-40 137.3 0.0 1.5e-25 89.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Pkinase PF00069.20 KOS15542.1 - 1.8e-59 200.9 0.0 2.5e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15542.1 - 3.9e-26 91.6 0.0 5.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Got1 PF04178.7 KOS15542.1 - 3.8e-19 68.9 13.0 6.6e-19 68.1 9.0 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Kinase-like PF14531.1 KOS15542.1 - 0.0088 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ABC_tran PF00005.22 KOS15543.1 - 9e-35 119.9 0.1 9.4e-17 61.5 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 KOS15543.1 - 2.6e-14 52.4 3.7 6.7e-14 51.1 2.6 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KOS15543.1 - 5.1e-14 52.9 3.1 0.07 13.0 0.0 4.3 2 2 0 4 4 4 4 AAA domain SMC_N PF02463.14 KOS15543.1 - 2.1e-11 43.4 3.8 9.9e-05 21.6 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 KOS15543.1 - 1.1e-07 31.0 3.2 1.1e-07 31.0 2.2 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_15 PF13175.1 KOS15543.1 - 1.4e-07 30.9 2.2 0.23 10.4 0.1 4.6 5 0 0 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 KOS15543.1 - 1.1e-06 28.8 0.1 0.0024 18.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KOS15543.1 - 4.7e-06 26.8 0.1 0.02 15.0 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.2 KOS15543.1 - 7.6e-06 25.5 11.0 4.1e-05 23.2 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain DUF258 PF03193.11 KOS15543.1 - 1.2e-05 24.6 1.9 0.061 12.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS15543.1 - 2.1e-05 23.9 1.2 0.04 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 KOS15543.1 - 3e-05 23.7 1.3 0.0036 16.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KOS15543.1 - 4e-05 23.1 0.1 0.027 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 KOS15543.1 - 7.2e-05 23.0 6.9 0.00036 20.8 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_17 PF13207.1 KOS15543.1 - 9.8e-05 23.1 0.0 0.55 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain VirE PF05272.6 KOS15543.1 - 0.00038 19.9 0.0 0.4 10.1 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E Miro PF08477.8 KOS15543.1 - 0.00042 20.7 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 KOS15543.1 - 0.00052 20.1 0.3 0.18 11.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 KOS15543.1 - 0.00058 19.7 0.4 0.098 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 KOS15543.1 - 0.0007 19.3 2.4 0.0007 19.3 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 KOS15543.1 - 0.00071 19.6 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 KOS15543.1 - 0.00087 19.0 11.2 0.002 17.9 7.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KOS15543.1 - 0.0016 18.6 2.0 0.0016 18.6 1.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_18 PF13238.1 KOS15543.1 - 0.0021 18.3 0.4 1.2 9.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KOS15543.1 - 0.0025 17.5 1.9 0.29 10.8 0.1 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KOS15543.1 - 0.0025 17.6 0.0 3 7.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 KOS15543.1 - 0.0032 17.2 1.4 0.0032 17.2 1.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain UPF0079 PF02367.12 KOS15543.1 - 0.0036 16.9 0.4 0.049 13.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_16 PF13484.1 KOS15543.1 - 0.005 17.5 5.3 0.0056 17.4 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Rad17 PF03215.10 KOS15543.1 - 0.0058 15.3 0.0 1.9 7.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KOS15543.1 - 0.0066 16.3 1.2 3.2 7.6 0.0 3.3 2 2 2 4 4 4 0 AAA domain AAA_28 PF13521.1 KOS15543.1 - 0.0073 16.2 0.3 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KOS15543.1 - 0.0095 14.8 0.0 0.72 8.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.1 KOS15543.1 - 0.012 15.9 0.9 0.012 15.9 0.6 2.8 2 1 1 3 3 3 0 AAA domain SRP54 PF00448.17 KOS15543.1 - 0.012 15.0 3.6 0.34 10.3 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_3 PF12798.2 KOS15543.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.4 2 0 0 2 2 1 0 4Fe-4S binding domain Thymidylate_kin PF02223.12 KOS15543.1 - 0.035 13.4 0.2 9 5.6 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.1 KOS15543.1 - 0.043 13.4 1.2 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 KOS15543.1 - 0.054 13.8 0.2 0.054 13.8 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_10 PF12846.2 KOS15543.1 - 0.093 12.1 1.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Fer4_8 PF13183.1 KOS15543.1 - 0.096 12.7 8.9 0.32 11.0 6.2 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain ArgK PF03308.11 KOS15543.1 - 0.1 11.3 0.4 1 8.0 0.0 2.1 2 0 0 2 2 2 0 ArgK protein MMR_HSR1 PF01926.18 KOS15543.1 - 0.12 12.2 0.6 11 5.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 KOS15543.1 - 0.14 11.0 0.0 9.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KOS15543.1 - 0.16 11.6 2.2 2.7 7.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Fer4_4 PF12800.2 KOS15543.1 - 0.17 12.2 13.7 0.055 13.8 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 KOS15543.1 - 7.8 7.1 10.2 0.098 13.2 0.8 2.5 3 0 0 3 3 1 0 4Fe-4S single cluster domain Glyco_transf_20 PF00982.16 KOS15544.1 - 7.7e-146 486.2 0.0 1.1e-145 485.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KOS15544.1 - 4.1e-72 241.8 0.0 7.4e-72 241.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KOS15544.1 - 4.1e-07 29.8 0.0 0.013 15.0 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase ERCC4 PF02732.10 KOS15545.1 - 3.8e-26 91.5 0.0 1.2e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain Peptidase_M17 PF00883.16 KOS15546.1 - 1e-114 382.6 0.0 1.4e-114 382.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KOS15546.1 - 1.3e-06 28.1 0.2 3.1e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Tfb2 PF03849.9 KOS15548.1 - 4.7e-125 417.0 1.1 7.2e-125 416.4 0.7 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 SNF2_N PF00176.18 KOS15548.1 - 1.1e-40 139.2 0.0 2e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS15548.1 - 2.6e-12 46.4 0.0 6e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KOS15548.1 - 1e-07 31.0 0.0 3.7e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C_3 PF13625.1 KOS15548.1 - 4.8e-05 23.1 0.0 0.00042 20.0 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Acyl-CoA_dh_1 PF00441.19 KOS15549.1 - 4.1e-46 156.7 3.6 4.1e-46 156.7 2.5 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KOS15549.1 - 1.3e-26 93.3 0.6 4.2e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KOS15549.1 - 3e-23 82.5 1.3 6.4e-23 81.4 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KOS15549.1 - 3.1e-17 61.8 0.0 6.3e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AgrD PF05931.6 KOS15549.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal AgrD protein Prefoldin_2 PF01920.15 KOS15549.1 - 1.6 8.5 4.3 6.1 6.6 0.0 2.5 3 0 0 3 3 3 0 Prefoldin subunit RRM_1 PF00076.17 KOS15550.1 - 3.4e-24 84.2 0.0 1.7e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15550.1 - 1.8e-15 56.6 0.0 3.8e-07 30.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15550.1 - 1.5e-10 40.7 0.0 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS15550.1 - 0.00094 18.9 0.0 0.0069 16.1 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KOS15550.1 - 0.0045 16.8 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Pro_isomerase PF00160.16 KOS15551.1 - 3.5e-40 137.7 0.0 4.1e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KOS15552.1 - 4e-18 64.8 0.0 6.3e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15552.1 - 3.8e-10 39.5 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15552.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2183 PF09949.4 KOS15552.1 - 0.063 13.2 0.0 1.5 8.8 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) WD40 PF00400.27 KOS15553.1 - 3.6e-51 169.3 23.7 1.1e-10 40.9 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KOS15553.1 - 2e-28 99.2 0.0 5.1e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KOS15553.1 - 0.00069 17.8 4.2 1.1 7.2 0.0 3.6 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF3886 PF13025.1 KOS15553.1 - 0.18 11.8 2.2 0.44 10.5 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) WD40 PF00400.27 KOS15554.1 - 2.8e-56 185.4 15.3 8.8e-10 38.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 KOS15554.1 - 0.00088 19.4 1.3 13 6.2 0.2 3.8 2 1 1 3 3 3 3 PQQ-like domain Gmad1 PF10647.4 KOS15554.1 - 0.0084 15.5 0.3 0.24 10.7 0.0 2.9 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 KOS15554.1 - 0.18 10.0 0.0 0.4 8.9 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain TCTP PF00838.12 KOS15555.1 - 7.7e-66 221.1 1.6 8.6e-66 220.9 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 KOS15555.1 - 0.068 12.9 0.3 0.12 12.1 0.2 1.4 1 1 0 1 1 1 0 Spore germination protein GerPC Rsbr_N PF08678.5 KOS15555.1 - 0.088 12.6 0.1 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Rsbr N terminal TroA PF01297.12 KOS15555.1 - 0.089 12.0 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family Isy1 PF06246.7 KOS15556.1 - 1e-78 264.2 0.9 1.3e-78 263.9 0.6 1.1 1 0 0 1 1 1 1 Isy1-like splicing family LRR_4 PF12799.2 KOS15557.1 - 0.00013 21.4 0.8 1.1 8.9 0.1 4.6 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS15557.1 - 0.00015 21.3 0.1 1.3 9.3 0.0 5.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 KOS15557.1 - 0.00065 19.5 0.5 16 5.9 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 KOS15557.1 - 0.0025 17.5 0.5 1.7 8.4 0.1 3.5 3 1 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 KOS15557.1 - 0.06 13.5 3.5 14 6.3 0.0 4.7 4 0 0 4 4 4 0 Leucine rich repeat DAO PF01266.19 KOS15558.1 - 6.6e-49 166.7 0.0 9.7e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KOS15558.1 - 1.3e-09 37.9 0.1 4.3e-09 36.2 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS15558.1 - 3.9e-09 36.6 0.0 0.00054 19.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KOS15558.1 - 2.4e-07 29.9 1.1 0.0068 15.2 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 KOS15558.1 - 6.6e-06 25.4 0.2 1.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KOS15558.1 - 9.2e-06 24.7 0.1 0.034 12.9 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 KOS15558.1 - 1.2e-05 25.6 0.1 6.1e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KOS15558.1 - 2.8e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KOS15558.1 - 0.00064 19.1 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KOS15558.1 - 0.0018 17.6 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KOS15558.1 - 0.0025 16.3 0.1 0.15 10.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_10 PF13460.1 KOS15558.1 - 0.0025 17.8 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding ThiF PF00899.16 KOS15558.1 - 0.0028 17.4 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 KOS15558.1 - 0.003 17.5 0.0 0.0082 16.1 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KOS15558.1 - 0.0053 15.7 0.1 0.0097 14.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_9 PF13454.1 KOS15558.1 - 0.0066 16.2 0.1 0.88 9.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KOS15558.1 - 0.0092 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KOS15558.1 - 0.011 15.8 0.1 0.11 12.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KOS15558.1 - 0.012 16.0 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 KOS15558.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KOS15558.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KOS15558.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KOS15558.1 - 0.054 13.2 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.4 KOS15558.1 - 0.076 12.7 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Rossmann-like domain Amino_oxidase PF01593.19 KOS15558.1 - 0.081 11.9 0.3 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.14 KOS15558.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KOS15558.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KOS15558.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KOS15558.1 - 0.21 10.1 0.1 0.42 9.1 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Ribosomal_L27e PF01777.13 KOS15559.1 - 1.3e-35 121.3 0.9 1.3e-35 121.3 0.7 1.8 2 0 0 2 2 2 1 Ribosomal L27e protein family GHMP_kinases_N PF00288.21 KOS15559.1 - 1.8e-07 31.0 2.8 3.8e-07 30.0 1.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain KOW PF00467.24 KOS15559.1 - 0.0036 16.9 1.7 0.01 15.5 1.2 1.8 1 0 0 1 1 1 1 KOW motif TFIIA PF03153.8 KOS15560.1 - 7.1e-50 170.9 20.5 6.2e-30 105.3 13.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2201_N PF13203.1 KOS15560.1 - 0.016 14.4 2.3 0.017 14.2 1.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Cwf_Cwc_15 PF04889.7 KOS15560.1 - 0.033 13.9 10.8 0.038 13.6 7.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 KOS15560.1 - 0.1 10.9 12.6 0.12 10.7 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 KOS15560.1 - 0.37 10.1 9.1 0.43 9.9 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 KOS15560.1 - 1.2 8.9 6.6 1.5 8.6 4.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 KOS15560.1 - 2.8 7.3 12.5 4 6.8 8.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SRP-alpha_N PF04086.8 KOS15560.1 - 5.7 6.2 14.2 13 5.1 9.9 1.6 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.4 KOS15560.1 - 6.7 5.4 7.2 8.3 5.1 5.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 KOS15560.1 - 9.3 4.1 9.0 12 3.7 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3295 PF11702.3 KOS15561.1 - 5.7e-12 45.3 2.8 5.7e-12 45.3 1.9 4.7 1 1 3 5 5 5 2 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KOS15561.1 - 4.5e-08 32.5 0.0 4.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Pet127 PF08634.5 KOS15562.1 - 1.2e-108 362.3 0.1 1.8e-108 361.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LMBR1 PF04791.11 KOS15562.1 - 0.16 10.5 0.1 0.25 9.8 0.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Dicty_REP PF05086.7 KOS15562.1 - 0.88 7.2 11.1 1.3 6.7 7.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sulfate_transp PF00916.15 KOS15563.1 - 5.7e-16 58.3 7.3 1.3e-14 53.8 5.1 2.5 1 1 0 1 1 1 1 Sulfate transporter family Peptidase_S41 PF03572.13 KOS15563.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 DUF3292 PF11696.3 KOS15564.1 - 2.3e-10 39.0 0.6 0.00026 19.0 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 KOS15564.1 - 2.3e-06 27.1 4.5 0.0002 20.9 0.4 2.8 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 KOS15564.1 - 0.007 15.9 7.7 0.039 13.5 0.6 2.6 2 0 0 2 2 2 2 Reticulon DUF3753 PF12575.3 KOS15564.1 - 0.16 11.7 0.1 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) eIF3_N PF09440.5 KOS15565.1 - 8.5e-35 119.8 3.5 1.7e-34 118.8 2.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KOS15565.1 - 4.1e-08 33.4 0.0 1.3e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.1 KOS15565.1 - 0.017 15.4 0.8 0.054 13.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KOS15565.1 - 0.026 14.1 0.0 0.077 12.6 0.0 1.8 1 0 0 1 1 1 0 TPR repeat RNA_pol_I_A49 PF06870.7 KOS15566.1 - 2.4e-74 250.2 0.0 2.9e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor YbgS PF13985.1 KOS15566.1 - 0.0077 16.1 1.3 0.014 15.3 0.4 1.8 2 0 0 2 2 2 1 YbgS-like protein Glycoamylase PF10091.4 KOS15566.1 - 0.022 13.8 0.3 0.042 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative glucoamylase GntR PF00392.16 KOS15566.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Tcf25 PF04910.9 KOS15567.1 - 1.5e-75 254.4 0.1 5.8e-75 252.4 0.0 2.0 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_2 PF07719.12 KOS15567.1 - 7.1 6.8 7.7 41 4.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0197 PF05251.7 KOS15568.1 - 6.5e-06 26.3 2.1 9.4e-06 25.8 1.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) DUF202 PF02656.10 KOS15568.1 - 0.067 13.4 1.7 0.091 12.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.16 KOS15568.1 - 6.9 6.6 8.0 0.58 10.0 0.5 2.1 2 0 0 2 2 2 0 Gram positive anchor W2 PF02020.13 KOS15569.1 - 4.9e-17 61.6 0.2 1.7e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_mis_repair PF01119.14 KOS15570.1 - 3e-31 107.3 0.0 5.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KOS15570.1 - 1.9e-11 43.7 0.0 4.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KOS15570.1 - 1.3e-10 40.9 0.0 4.1e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 KOS15571.1 - 8.2e-62 208.6 0.0 1.3e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15571.1 - 8.5e-37 126.6 0.0 5.7e-35 120.6 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15571.1 - 1.6e-05 24.0 0.0 2.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Apt1 PF10351.4 KOS15571.1 - 0.26 10.1 4.3 0.44 9.3 3.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain APH PF01636.18 KOS15571.1 - 0.27 10.9 0.1 0.27 10.9 0.0 4.3 3 3 1 4 4 4 0 Phosphotransferase enzyme family DUF4200 PF13863.1 KOS15571.1 - 0.5 10.3 22.7 0.062 13.2 3.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 KOS15571.1 - 7.9 6.5 10.9 0.29 11.1 2.3 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SNF2_N PF00176.18 KOS15572.1 - 9.1e-68 228.2 0.0 1.4e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS15572.1 - 3.3e-13 49.2 0.0 4.2e-12 45.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS15572.1 - 3.7e-08 33.0 0.0 2.6e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS15572.1 - 1.3e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1115 PF06544.7 KOS15572.1 - 0.028 14.1 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Carn_acyltransf PF00755.15 KOS15573.1 - 2.3e-157 524.6 0.0 2.7e-157 524.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNase_H PF00075.19 KOS15574.1 - 3.9e-31 108.1 0.0 5.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KOS15574.1 - 3.4e-19 68.5 0.2 7.2e-19 67.5 0.2 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.1 KOS15574.1 - 0.08 12.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Yip1 PF04893.12 KOS15575.1 - 3.6e-11 42.8 8.5 4.7e-11 42.4 5.9 1.2 1 0 0 1 1 1 1 Yip1 domain Rota_NSP4 PF01452.11 KOS15575.1 - 0.062 12.6 0.2 0.079 12.2 0.1 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein PP2C PF00481.16 KOS15576.1 - 6.9e-72 241.9 0.2 8.3e-72 241.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KOS15576.1 - 0.045 13.4 1.1 0.4 10.3 0.7 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) EBP PF05241.7 KOS15577.1 - 7e-51 172.0 7.8 8.2e-51 171.7 5.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein FHA PF00498.21 KOS15578.1 - 3.6e-08 33.3 0.0 8.9e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 FHA domain NR_Repeat PF14046.1 KOS15579.1 - 0.53 10.0 2.1 1 9.1 0.1 2.4 3 0 0 3 3 3 0 Nuclear receptor repeat Telomerase_RBD PF12009.3 KOS15580.1 - 1.3e-29 102.8 0.8 2.7e-29 101.7 0.5 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KOS15580.1 - 4.1e-11 42.6 0.0 1.9e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLA2_B PF01735.13 KOS15581.1 - 6.2e-16 57.6 0.2 2e-08 32.8 0.5 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain NatB_MDM20 PF09797.4 KOS15582.1 - 1.4e-57 195.1 3.8 2.9e-57 194.0 1.9 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit SpoVAD PF07451.6 KOS15582.1 - 0.0044 15.5 0.0 0.0081 14.6 0.0 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Muted PF14942.1 KOS15582.1 - 0.033 14.0 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein TPR_14 PF13428.1 KOS15582.1 - 1.4 9.7 5.4 42 5.1 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 KOS15583.1 - 1.8e-07 30.5 0.0 6.7e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KOS15583.1 - 7.9e-07 28.4 0.0 2.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Glyco_hydro_2_C PF02836.12 KOS15583.1 - 0.00041 19.3 0.0 0.00061 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HEAT PF02985.17 KOS15583.1 - 0.0018 18.1 1.2 0.51 10.5 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KOS15583.1 - 0.0084 16.3 0.2 0.17 12.1 0.1 2.9 2 1 1 3 3 3 1 HEAT repeats DUF1542 PF07564.6 KOS15583.1 - 0.19 11.7 1.4 0.5 10.4 1.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) HEAT_EZ PF13513.1 KOS15583.1 - 0.47 11.0 5.3 0.48 10.9 0.0 3.7 3 1 0 3 3 3 0 HEAT-like repeat Peptidase_C54 PF03416.14 KOS15584.1 - 6.1e-66 222.3 0.0 7.5e-65 218.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 ATG13 PF10033.4 KOS15585.1 - 1.1e-39 136.2 0.0 2.1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF2229 PF09989.4 KOS15586.1 - 1.6 8.1 4.1 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Seryl_tRNA_N PF02403.17 KOS15586.1 - 6.5 6.8 12.2 3.3 7.7 2.2 3.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRO1 PF03097.13 KOS15587.1 - 5.7e-16 58.2 0.0 7.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain UCH PF00443.24 KOS15588.1 - 3.7e-46 157.4 0.0 4.4e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS15588.1 - 2.3e-19 69.9 0.0 2.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 KOS15589.1 - 4.8e-11 42.1 5.3 9.3e-11 41.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15589.1 - 1.2e-07 31.2 5.0 2.7e-07 30.1 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15589.1 - 1.7e-07 31.1 3.4 4.5e-07 29.7 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS15589.1 - 1.2e-06 28.2 6.0 3e-06 26.9 4.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KOS15589.1 - 6.7e-05 22.5 4.9 0.00014 21.4 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KOS15589.1 - 0.025 14.4 6.7 0.28 11.0 4.7 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.7 KOS15589.1 - 0.16 11.8 5.6 1.7 8.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) mono-CXXC PF15626.1 KOS15589.1 - 0.27 11.1 2.6 0.59 10.1 1.8 1.6 1 0 0 1 1 1 0 single CXXC unit Prok-RING_4 PF14447.1 KOS15589.1 - 0.46 10.0 5.1 1.2 8.6 1.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KOS15589.1 - 0.8 9.4 5.6 0.76 9.5 2.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KOS15589.1 - 8.4 6.0 7.7 61 3.3 5.4 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF2781 PF10914.3 KOS15590.1 - 9.1e-27 93.6 9.2 1.3e-26 93.1 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pterin_4a PF01329.14 KOS15590.1 - 3.9e-23 81.0 0.1 5.7e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PAPA-1 PF04795.7 KOS15591.1 - 4.7e-20 72.0 3.5 4.7e-20 72.0 2.5 2.5 2 1 0 2 2 2 1 PAPA-1-like conserved region Ribonucleas_3_3 PF14622.1 KOS15592.1 - 1.8e-30 105.5 0.0 3.6e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KOS15592.1 - 1.2e-06 28.9 0.0 2.9e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain ShlB PF03865.8 KOS15592.1 - 0.03 13.0 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Ribosomal_L37 PF08561.5 KOS15593.1 - 2e-25 88.1 10.6 3.1e-21 74.7 1.0 2.7 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DUF1289 PF06945.8 KOS15593.1 - 0.014 14.8 2.1 0.014 14.8 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF2992 PF11208.3 KOS15593.1 - 6.2 6.7 12.6 8 6.3 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Borrelia_P83 PF05262.6 KOS15593.1 - 7.7 4.6 12.1 9.6 4.3 8.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DPBB_1 PF03330.13 KOS15594.1 - 0.00022 21.1 0.1 0.00033 20.6 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Vps16_C PF04840.7 KOS15595.1 - 2e-51 174.8 0.1 1.7e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 KOS15595.1 - 6.5e-48 163.2 0.0 6.5e-28 97.3 0.0 3.2 3 0 0 3 3 3 3 Vps16, N-terminal region Apc4_WD40 PF12894.2 KOS15595.1 - 0.0052 16.2 0.0 1.7 8.2 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain GATA PF00320.22 KOS15596.1 - 0.00016 20.9 9.9 0.013 14.8 0.8 3.0 2 1 0 2 2 2 2 GATA zinc finger Maf1 PF09174.5 KOS15597.1 - 2.6e-34 118.6 0.0 7.4e-29 100.8 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator MRP-L27 PF09809.4 KOS15598.1 - 1.6e-05 24.4 0.4 0.0019 17.8 0.3 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF202 PF02656.10 KOS15599.1 - 9.1e-22 77.0 0.2 9.1e-22 77.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2189 PF09955.4 KOS15599.1 - 0.37 10.7 8.2 0.26 11.2 2.6 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DNA_pol_delta_4 PF04081.8 KOS15600.1 - 1.4e-20 73.7 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Abhydrolase_5 PF12695.2 KOS15601.1 - 0.00066 19.4 0.0 0.00096 18.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KOS15601.1 - 0.001 18.8 0.1 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase WD40 PF00400.27 KOS15602.1 - 2e-69 227.1 16.4 2.8e-12 46.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KOS15602.1 - 6e-21 74.4 2.5 1.3e-20 73.4 1.7 1.6 1 0 0 1 1 1 1 Tup N-terminal Nbas_N PF15492.1 KOS15602.1 - 0.00039 19.6 0.4 0.072 12.1 0.0 3.4 2 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KOS15602.1 - 0.0014 18.2 0.7 12 5.6 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KOS15602.1 - 0.0039 15.5 0.1 0.087 11.0 0.0 2.4 1 1 0 2 2 2 1 Cytochrome D1 heme domain Spc7 PF08317.6 KOS15602.1 - 0.028 13.0 0.1 0.046 12.3 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PQQ_2 PF13360.1 KOS15602.1 - 0.069 12.5 0.1 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain DUF3450 PF11932.3 KOS15602.1 - 0.1 11.8 0.8 0.35 10.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Proteasome_A_N PF10584.4 KOS15602.1 - 0.27 10.5 1.0 32 3.9 0.0 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Pribosyltran_N PF13793.1 KOS15603.1 - 1.1e-42 144.4 0.1 1.1e-40 137.9 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KOS15603.1 - 2.2e-33 115.5 1.5 3.7e-32 111.5 1.0 2.2 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KOS15603.1 - 3.9e-13 49.2 0.1 5.6e-12 45.4 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Ribosomal_L7Ae PF01248.21 KOS15604.1 - 2e-29 100.9 1.2 2.4e-29 100.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Coatomer_WDAD PF04053.9 KOS15605.1 - 6.7e-141 470.0 0.0 4.6e-140 467.3 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KOS15605.1 - 5.3e-52 171.9 12.8 1.7e-10 40.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KOS15605.1 - 0.025 12.7 1.9 1.3 7.1 0.0 3.8 5 0 0 5 5 5 0 Nucleoporin Nup120/160 Vac14_Fig4_bd PF11916.3 KOS15606.1 - 4.3e-72 241.0 11.1 4.3e-72 241.0 7.7 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KOS15606.1 - 7.5e-42 141.6 0.0 1.4e-37 127.9 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KOS15606.1 - 5.7e-15 53.9 11.3 0.00013 21.7 0.0 8.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KOS15606.1 - 5.9e-11 42.5 0.0 0.018 15.2 0.0 5.1 3 2 0 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 KOS15606.1 - 0.00021 21.6 0.0 10 6.7 0.0 5.2 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 KOS15606.1 - 0.0006 19.7 2.6 0.83 9.4 0.0 4.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.8 KOS15606.1 - 0.0054 15.8 1.0 0.031 13.3 0.0 2.5 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.3 KOS15606.1 - 0.0065 15.2 0.4 0.0065 15.2 0.2 3.1 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Ribosomal_L1 PF00687.16 KOS15607.1 - 3.9e-51 173.4 3.6 4.8e-51 173.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEAD PF00270.24 KOS15608.1 - 3.8e-20 72.0 0.6 8.9e-20 70.8 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15608.1 - 2.1e-18 65.9 0.0 1.5e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KOS15608.1 - 1.2e-05 25.0 0.1 4.7e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 RQC domain ResIII PF04851.10 KOS15608.1 - 3.2e-05 23.8 0.0 0.00013 21.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS15608.1 - 0.023 14.8 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SecA_DEAD PF07517.9 KOS15608.1 - 0.13 11.5 0.1 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain IncA PF04156.9 KOS15608.1 - 0.23 11.0 3.7 0.24 10.9 1.2 2.0 2 0 0 2 2 2 0 IncA protein RIO1 PF01163.17 KOS15609.1 - 4.8e-71 238.0 0.0 4.8e-71 238.0 0.0 2.5 3 0 0 3 3 3 1 RIO1 family SDA1 PF05285.7 KOS15609.1 - 1.1e-05 24.9 3.1 1.1e-05 24.9 2.1 2.3 2 1 0 2 2 2 1 SDA1 Kdo PF06293.9 KOS15609.1 - 0.00022 20.3 3.2 0.0046 16.0 2.2 2.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KOS15609.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CDC45 PF02724.9 KOS15609.1 - 0.35 8.8 19.8 0.037 12.0 10.4 1.7 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 KOS15609.1 - 9.5 3.9 26.9 0.05 11.5 12.4 1.6 2 0 0 2 2 2 0 Nop14-like family FSH1 PF03959.8 KOS15610.1 - 5e-51 173.1 0.0 5.8e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KOS15610.1 - 1.1e-05 25.4 0.0 0.11 12.3 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS15610.1 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family He_PIG_assoc PF10632.4 KOS15610.1 - 0.024 13.9 0.1 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Abhydrolase_2 PF02230.11 KOS15610.1 - 0.03 13.7 0.0 0.55 9.6 0.0 2.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase HA PF03457.9 KOS15610.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain PPR_3 PF13812.1 KOS15611.1 - 1.4e-05 25.0 13.3 0.057 13.7 0.0 6.5 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KOS15611.1 - 0.015 15.2 0.1 1.5 8.8 0.0 3.1 3 1 1 4 4 4 0 PPR repeat family PPR PF01535.15 KOS15611.1 - 0.092 12.7 0.3 6.3 7.0 0.0 3.1 2 0 0 2 2 2 0 PPR repeat PPR_1 PF12854.2 KOS15611.1 - 0.2 11.1 1.0 0.45 10.0 0.1 2.1 2 0 0 2 2 2 0 PPR repeat SPC22 PF04573.7 KOS15613.1 - 2.6e-40 137.5 0.0 2.9e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit OGG_N PF07934.7 KOS15613.1 - 0.061 13.2 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain CI-B14_5a PF07347.7 KOS15614.1 - 0.031 14.0 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) SPC25 PF06703.6 KOS15615.1 - 1.2e-17 64.0 0.0 1.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) WD40 PF00400.27 KOS15617.1 - 6.6e-20 70.1 0.3 3.1e-05 23.6 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KOS15617.1 - 0.073 11.3 0.3 0.36 9.0 0.2 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Phage_T4_gp19 PF06841.7 KOS15617.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 ABA_GPCR PF12430.3 KOS15618.1 - 6.1e-34 116.8 6.1 6.1e-34 116.8 4.3 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KOS15618.1 - 4.2e-12 45.9 0.1 9.3e-12 44.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) EMP24_GP25L PF01105.19 KOS15618.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2968 PF11180.3 KOS15618.1 - 0.19 11.0 4.4 6.4 6.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DASH_Duo1 PF08651.5 KOS15620.1 - 1.2e-15 56.8 3.3 2.1e-15 56.0 2.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 TSA PF03249.8 KOS15620.1 - 0.059 11.9 3.8 0.079 11.4 2.6 1.1 1 0 0 1 1 1 0 Type specific antigen Med2 PF11214.3 KOS15620.1 - 0.061 13.3 8.3 0.089 12.8 5.4 1.5 1 1 0 1 1 1 0 Mediator complex subunit 2 DUF572 PF04502.8 KOS15620.1 - 0.11 11.7 9.5 0.14 11.3 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 KOS15620.1 - 0.27 10.0 6.2 0.13 11.0 2.8 1.4 1 1 0 1 1 1 0 Golgi-body localisation protein domain IncA PF04156.9 KOS15620.1 - 0.28 10.7 8.8 0.37 10.3 6.1 1.2 1 0 0 1 1 1 0 IncA protein GTSE1_N PF15259.1 KOS15620.1 - 1.7 8.5 5.0 0.9 9.4 1.8 1.8 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 RNase_PH PF01138.16 KOS15621.1 - 2.1e-13 50.6 0.0 4.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS15621.1 - 4.7e-06 26.4 0.0 7.2e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 CDC48_N PF02359.13 KOS15621.1 - 0.023 14.6 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain RabGAP-TBC PF00566.13 KOS15622.1 - 9.9e-42 142.8 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CASP_C PF08172.7 KOS15623.1 - 1e-48 165.5 5.4 1e-48 165.5 3.8 3.8 1 1 1 2 2 2 1 CASP C terminal UBA PF00627.26 KOS15623.1 - 1.1e-18 66.4 1.4 3e-10 39.6 0.0 3.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 KOS15623.1 - 1.7e-13 49.7 4.6 1.7e-13 49.7 3.2 2.3 2 0 0 2 2 2 1 XPC-binding domain UBA_4 PF14555.1 KOS15623.1 - 0.0013 18.2 0.0 0.034 13.6 0.0 3.2 3 0 0 3 3 3 1 UBA-like domain CENP-F_leu_zip PF10473.4 KOS15623.1 - 0.012 15.5 5.0 0.012 15.5 3.5 5.2 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 KOS15623.1 - 0.17 11.6 6.9 0.19 11.5 1.8 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ANTH PF07651.11 KOS15624.1 - 1.1e-51 175.2 1.5 1.5e-51 174.8 1.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KOS15624.1 - 1.9e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 KOS15624.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 VHS domain Oxysterol_BP PF01237.13 KOS15625.1 - 1.9e-120 401.6 0.0 1.9e-120 401.6 0.0 1.5 2 0 0 2 2 1 1 Oxysterol-binding protein Ank_5 PF13857.1 KOS15625.1 - 3.6e-13 49.2 0.2 0.00027 21.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS15625.1 - 1.3e-11 44.6 0.3 3.7e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS15625.1 - 2.9e-11 43.5 0.2 0.00016 22.0 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS15625.1 - 3.5e-11 42.3 1.1 0.00053 19.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KOS15625.1 - 9.1e-11 40.9 0.3 0.063 13.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KOS15625.1 - 2.9e-08 33.8 0.2 9e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KOS15625.1 - 3e-07 30.6 0.2 1.2e-06 28.7 0.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KOS15625.1 - 5.2e-06 26.4 0.4 1.4e-05 25.0 0.2 1.8 2 0 0 2 2 1 1 Pleckstrin homology domain OmpH PF03938.9 KOS15625.1 - 0.015 15.2 1.1 0.015 15.2 0.8 1.9 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 KOS15625.1 - 0.22 9.3 1.4 0.38 8.5 1.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.14 KOS15625.1 - 4.8 7.6 25.0 8.7 6.8 8.9 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PPTA PF01239.17 KOS15626.1 - 2e-42 140.7 17.7 2.7e-09 35.9 0.0 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 KOS15626.1 - 0.088 13.0 2.5 62 4.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Dfp1_Him1_M PF08630.5 KOS15628.1 - 4.6e-28 97.5 0.0 8e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KOS15628.1 - 8.6e-19 66.9 3.3 1.4e-18 66.2 2.3 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 KOS15628.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain Prp19_bind PF06991.6 KOS15628.1 - 0.012 14.9 0.5 0.019 14.2 0.3 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain BRCT PF00533.21 KOS15628.1 - 0.023 14.8 0.0 0.059 13.5 0.0 1.8 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.11 KOS15629.1 - 1.1e-34 119.6 73.5 5.4e-30 104.2 43.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 KOS15629.1 - 0.039 13.5 0.2 0.067 12.7 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Gar1 PF04410.9 KOS15630.1 - 5.6e-35 120.0 0.0 1.1e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Adaptin_N PF01602.15 KOS15631.1 - 5.8e-86 288.8 0.0 7.9e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KOS15631.1 - 1.7e-09 37.8 5.4 0.00019 21.6 0.0 5.8 4 3 2 6 6 6 2 HEAT repeats HEAT PF02985.17 KOS15631.1 - 7.4e-08 31.8 1.4 1.7 8.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 KOS15631.1 - 0.00077 19.3 0.0 0.062 13.1 0.0 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KOS15631.1 - 0.0026 18.2 7.4 0.37 11.3 0.1 5.8 3 2 3 6 6 6 1 HEAT-like repeat DUF221 PF02714.10 KOS15632.1 - 6.4e-81 271.7 22.1 6.4e-81 271.7 15.3 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KOS15632.1 - 1.2e-22 80.0 7.8 9.5e-22 77.2 0.7 2.9 2 0 0 2 2 2 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KOS15632.1 - 3.1e-08 34.0 0.0 5.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) SNF2_N PF00176.18 KOS15633.1 - 2.3e-32 112.0 0.0 8.6e-25 87.1 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS15633.1 - 2e-09 37.1 0.0 3.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Rrn6 PF10214.4 KOS15634.1 - 1.5e-07 29.9 0.4 1.5e-07 29.9 0.3 3.4 3 1 1 4 4 4 2 RNA polymerase I-specific transcription-initiation factor PNRC PF15365.1 KOS15634.1 - 0.00017 21.5 7.9 0.0007 19.5 5.4 2.1 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator SAPS PF04499.10 KOS15635.1 - 7.3e-129 430.4 0.4 7.3e-129 430.4 0.3 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.14 KOS15635.1 - 0.13 10.0 1.7 0.2 9.4 1.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SMC_N PF02463.14 KOS15636.1 - 1.8e-63 213.7 0.6 2.5e-63 213.2 0.4 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS15636.1 - 5.4e-32 110.2 0.0 1.7e-31 108.6 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS15636.1 - 4.4e-13 49.8 0.0 4.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KOS15636.1 - 3.8e-08 32.8 0.0 3e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KOS15636.1 - 4.2e-07 29.4 0.0 1.5e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KOS15636.1 - 0.00058 19.7 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.3 KOS15636.1 - 0.0014 16.1 8.5 0.0014 16.1 5.9 5.1 4 1 1 5 5 4 2 Protein of unknown function (DUF3584) ABC_tran PF00005.22 KOS15636.1 - 0.012 15.9 0.0 0.012 15.9 0.0 5.8 5 2 0 5 5 4 0 ABC transporter FlaC_arch PF05377.6 KOS15636.1 - 0.028 14.3 3.1 4.1 7.3 0.0 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AAA_10 PF12846.2 KOS15636.1 - 0.83 9.0 0.0 0.83 9.0 0.0 4.3 3 2 0 3 3 2 0 AAA-like domain AAA_23 PF13476.1 KOS15636.1 - 4.5 7.5 70.8 0.27 11.5 25.9 5.5 2 2 0 2 2 1 0 AAA domain Reo_sigmaC PF04582.7 KOS15636.1 - 4.8 6.2 22.9 0.39 9.8 0.4 4.3 3 2 1 5 5 5 0 Reovirus sigma C capsid protein Peptidase_C50 PF03568.12 KOS15637.1 - 2.2e-65 220.8 0.0 4.9e-65 219.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C50 Prenyltrans PF00432.16 KOS15638.1 - 5.6e-25 86.5 12.4 2.1e-06 27.1 0.0 6.8 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS15638.1 - 3.6e-23 82.1 0.0 5.5e-09 36.4 0.0 3.7 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS15638.1 - 6.2e-05 22.9 0.0 0.077 13.0 0.0 3.5 1 1 3 4 4 4 3 Prenyltransferase-like Glyco_hydro_47 PF01532.15 KOS15639.1 - 2.5e-138 461.5 0.0 2.9e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FixP_N PF14715.1 KOS15639.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP MRG PF05712.8 KOS15640.1 - 1.9e-55 186.8 0.0 4.6e-55 185.5 0.0 1.5 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 KOS15640.1 - 8.1e-11 41.4 0.2 1.7e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3018 PF11455.3 KOS15640.1 - 0.063 13.2 0.7 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Chromo PF00385.19 KOS15640.1 - 0.063 12.9 0.9 0.14 11.8 0.6 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FNIP_N PF14636.1 KOS15640.1 - 0.12 12.8 3.3 0.23 11.9 2.3 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus PAG PF15347.1 KOS15640.1 - 0.31 10.1 3.5 0.52 9.3 2.4 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched VSG_B PF13206.1 KOS15640.1 - 4 6.4 11.8 7.8 5.5 8.2 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain Acyltransferase PF01553.16 KOS15641.1 - 5.4e-16 58.2 0.0 6.8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TFIIB PF00382.14 KOS15642.1 - 2.7e-34 116.7 0.1 2.2e-18 65.7 0.0 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KOS15642.1 - 1.3e-28 99.0 1.6 1.3e-28 99.0 1.1 2.9 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 KOS15642.1 - 1.1e-08 34.1 0.2 2.4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KOS15642.1 - 0.00022 20.8 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 KOS15642.1 - 0.0051 15.9 0.3 0.01 15.0 0.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain AAA PF00004.24 KOS15643.1 - 1.1e-38 132.4 0.0 1.9e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS15643.1 - 9.8e-07 28.0 0.0 2.6e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KOS15643.1 - 2e-06 27.9 0.1 0.00072 19.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KOS15643.1 - 3.1e-06 27.3 0.2 0.00011 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KOS15643.1 - 6.9e-06 26.8 0.0 1.7e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KOS15643.1 - 1.9e-05 24.6 0.0 4.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KOS15643.1 - 3e-05 23.7 0.2 0.00015 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KOS15643.1 - 4.6e-05 23.3 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS15643.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KOS15643.1 - 7.6e-05 21.9 0.6 0.0014 17.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KOS15643.1 - 0.00027 20.4 0.3 0.00049 19.5 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KOS15643.1 - 0.00034 20.0 1.4 0.012 15.0 0.3 2.2 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KOS15643.1 - 0.00049 20.1 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KOS15643.1 - 0.00058 20.0 0.0 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KOS15643.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KOS15643.1 - 0.0012 17.6 0.0 0.0023 16.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 KOS15643.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KOS15643.1 - 0.0018 17.9 0.0 0.0044 16.6 0.0 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_28 PF13521.1 KOS15643.1 - 0.0023 17.9 0.1 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS15643.1 - 0.0024 16.9 0.1 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KOS15643.1 - 0.0042 16.8 0.8 0.015 14.9 0.3 2.0 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 KOS15643.1 - 0.0044 16.5 0.0 0.0096 15.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KOS15643.1 - 0.0075 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.16 KOS15643.1 - 0.01 15.3 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase KaiC PF06745.8 KOS15643.1 - 0.012 14.7 0.0 0.19 10.7 0.0 2.2 1 1 1 2 2 2 0 KaiC DUF815 PF05673.8 KOS15643.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 KOS15643.1 - 0.016 14.8 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KOS15643.1 - 0.018 14.6 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 KOS15643.1 - 0.032 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KOS15643.1 - 0.033 14.1 0.2 4.8 7.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 KOS15643.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KOS15643.1 - 0.047 12.9 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein IPT PF01745.11 KOS15643.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.7 KOS15643.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 KOS15643.1 - 0.076 12.7 0.0 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 KOS15643.1 - 0.12 12.6 0.1 0.41 10.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KOS15643.1 - 0.19 10.6 0.7 2.8 6.8 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain CPSase_L_D2 PF02786.12 KOS15644.1 - 8.3e-114 378.1 0.1 2.6e-82 275.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 KOS15644.1 - 4.4e-44 149.5 0.0 9.4e-44 148.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 KOS15644.1 - 2e-43 147.0 0.0 4.8e-43 145.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KOS15644.1 - 5e-43 146.7 0.0 1.2e-42 145.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 KOS15644.1 - 5.4e-43 145.6 0.1 1.1e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KOS15644.1 - 1.4e-40 137.7 0.0 7.1e-21 74.3 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KOS15644.1 - 3.7e-36 124.5 0.1 5.9e-22 78.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KOS15644.1 - 5.3e-36 123.8 0.0 1.2e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KOS15644.1 - 9.8e-20 70.5 0.0 5.9e-11 41.6 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KOS15644.1 - 1.2e-16 60.7 0.0 8e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KOS15644.1 - 3.3e-15 55.8 0.0 9.4e-07 28.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KOS15644.1 - 3.6e-13 49.2 0.0 6.1e-12 45.3 0.0 3.0 3 0 0 3 3 2 1 MGS-like domain ATP-grasp_3 PF02655.9 KOS15644.1 - 6.4e-07 29.3 0.1 0.0058 16.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KOS15644.1 - 2.6e-05 23.7 0.0 0.0012 18.3 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 KOS15644.1 - 0.0024 17.3 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Hydrolase PF00702.21 KOS15644.1 - 0.011 16.1 0.0 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Met_10 PF02475.11 KOS15645.1 - 1.4e-58 197.7 0.0 1.9e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KOS15645.1 - 0.0034 17.4 0.6 0.01 15.8 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS15645.1 - 0.0096 16.4 0.0 0.042 14.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain cobW PF02492.14 KOS15646.1 - 2.2e-48 164.0 2.0 1.2e-47 161.6 1.4 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 KOS15646.1 - 4.2e-26 91.3 0.0 1.3e-25 89.8 0.0 1.8 1 0 0 1 1 1 1 HIT domain CobW_C PF07683.9 KOS15646.1 - 1.8e-21 75.6 0.5 2.8e-15 55.8 0.0 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 KOS15646.1 - 7.9e-09 35.7 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ArgK PF03308.11 KOS15646.1 - 0.0041 15.9 0.1 2 7.0 0.0 2.3 2 0 0 2 2 2 2 ArgK protein UPF0079 PF02367.12 KOS15646.1 - 0.011 15.3 0.1 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KOS15646.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KOS15646.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Nitr_red_bet_C PF14711.1 KOS15646.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal AAA_22 PF13401.1 KOS15646.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KOS15647.1 - 1.5e-46 158.0 0.0 8.6e-22 77.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KOS15647.1 - 6.6e-21 75.5 0.1 0.00058 19.9 0.0 4.5 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 KOS15647.1 - 9.8e-20 70.1 3.3 9.8e-20 70.1 2.3 2.3 3 0 0 3 3 1 1 ABC transporter AAA_23 PF13476.1 KOS15647.1 - 2.6e-11 44.2 3.7 0.00017 21.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KOS15647.1 - 7.3e-10 38.2 0.2 0.00028 20.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KOS15647.1 - 2.3e-09 36.8 2.5 0.26 10.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KOS15647.1 - 2.9e-07 31.3 0.8 0.021 15.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KOS15647.1 - 1.2e-06 27.8 8.5 0.18 10.7 0.0 4.8 4 1 0 5 5 5 3 AAA ATPase domain Miro PF08477.8 KOS15647.1 - 1.7e-06 28.5 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KOS15647.1 - 1.9e-06 28.0 1.1 0.017 15.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KOS15647.1 - 2e-06 27.1 0.0 0.00077 18.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KOS15647.1 - 2.5e-06 27.6 0.1 0.067 13.1 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 KOS15647.1 - 1e-05 25.4 0.9 0.013 15.4 0.3 3.1 3 1 0 3 3 2 1 50S ribosome-binding GTPase MobB PF03205.9 KOS15647.1 - 2.1e-05 24.2 1.1 0.29 10.8 0.1 3.6 2 1 1 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KOS15647.1 - 2.4e-05 24.0 0.1 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KOS15647.1 - 3.9e-05 23.9 1.1 0.21 11.8 0.0 3.6 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KOS15647.1 - 9.9e-05 21.9 0.1 0.51 9.7 0.0 2.8 2 1 0 2 2 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 KOS15647.1 - 0.00012 22.0 0.0 0.33 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KOS15647.1 - 0.00014 21.2 0.0 0.31 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KOS15647.1 - 0.00015 21.6 5.6 0.22 11.3 0.1 4.0 3 1 1 4 4 3 2 Dynamin family DUF87 PF01935.12 KOS15647.1 - 0.00019 21.3 4.4 1.3 8.7 0.0 4.3 3 1 1 4 4 4 1 Domain of unknown function DUF87 AAA_33 PF13671.1 KOS15647.1 - 0.00034 20.5 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KOS15647.1 - 0.00053 19.8 0.0 0.28 11.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KOS15647.1 - 0.00074 19.0 0.2 0.54 9.6 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain FeoB_N PF02421.13 KOS15647.1 - 0.00079 18.7 0.2 0.042 13.1 0.2 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA PF00004.24 KOS15647.1 - 0.00089 19.4 0.5 1.6 8.9 0.0 3.8 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KOS15647.1 - 0.0021 17.9 0.1 16 5.4 0.0 4.1 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 KOS15647.1 - 0.0032 16.9 0.1 0.61 9.5 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KOS15647.1 - 0.0033 17.5 0.8 4.8 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Pox_A32 PF04665.7 KOS15647.1 - 0.0045 16.3 0.2 1.6 7.9 0.0 3.0 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_5 PF07728.9 KOS15647.1 - 0.006 16.3 0.4 4.2 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 KOS15647.1 - 0.012 14.4 0.0 3.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 KOS15647.1 - 0.013 15.2 0.2 2 8.2 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 KOS15647.1 - 0.017 13.9 0.0 4.6 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KOS15647.1 - 0.02 14.4 3.9 0.82 9.2 0.0 3.4 5 0 0 5 5 2 0 AAA domain AAA_24 PF13479.1 KOS15647.1 - 0.023 14.2 0.1 4.9 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KOS15647.1 - 0.028 13.9 0.7 1.4 8.3 0.0 3.0 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KOS15647.1 - 0.033 13.6 0.8 5.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Thymidylate_kin PF02223.12 KOS15647.1 - 0.037 13.4 0.2 19 4.5 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_13 PF13166.1 KOS15647.1 - 0.051 12.0 4.5 1.4 7.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.21 KOS15647.1 - 0.059 12.8 0.0 5.3 6.4 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KOS15647.1 - 0.062 13.0 4.7 4.1 7.0 0.2 3.8 4 0 0 4 4 4 0 NTPase Septin PF00735.13 KOS15647.1 - 0.19 10.7 5.5 4.4 6.2 0.0 3.0 4 0 0 4 4 3 0 Septin Rad60-SLD PF11976.3 KOS15648.1 - 6.1e-25 86.6 0.3 7.1e-25 86.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KOS15648.1 - 4.8e-11 41.8 0.0 5.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF4115 PF13464.1 KOS15648.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) DUF3085 PF11284.3 KOS15648.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) zf-CSL PF05207.8 KOS15649.1 - 4.6e-25 86.8 1.4 5.2e-25 86.7 0.9 1.0 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 KOS15649.1 - 0.0096 15.4 0.5 0.013 15.0 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KOS15649.1 - 0.026 14.1 0.7 0.036 13.7 0.5 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 KOS15649.1 - 0.048 13.2 2.4 0.09 12.3 1.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF164 PF02591.10 KOS15649.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 2 0 0 2 2 2 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 KOS15649.1 - 0.097 12.6 0.9 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF4109 PF13397.1 KOS15649.1 - 0.15 12.4 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) TF_Zn_Ribbon PF08271.7 KOS15649.1 - 0.21 10.9 2.9 0.24 10.7 0.9 1.9 1 1 0 2 2 2 0 TFIIB zinc-binding GTSE1_N PF15259.1 KOS15650.1 - 0.013 15.5 3.7 0.013 15.5 2.6 2.3 2 1 0 2 2 2 0 G-2 and S-phase expressed 1 SOBP PF15279.1 KOS15650.1 - 2.5 8.4 19.9 4.6 7.5 4.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Misat_Tub_SegII PF10644.4 KOS15651.1 - 1.7e-27 95.7 0.0 3.3e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KOS15651.1 - 5.2e-26 91.2 0.1 9.4e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KOS15651.1 - 0.0013 18.5 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tim17 PF02466.14 KOS15652.1 - 0.0075 16.3 0.3 0.71 9.9 0.0 3.1 3 0 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 KOS15653.1 - 1.6e-34 119.2 0.0 2.7e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15653.1 - 1.4e-17 63.6 0.0 4.3e-16 58.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15653.1 - 5.8e-05 22.1 0.0 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like bZIP_2 PF07716.10 KOS15653.1 - 0.14 12.0 0.7 0.31 10.8 0.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Pex24p PF06398.6 KOS15654.1 - 8.9e-06 24.7 4.1 2.6e-05 23.2 2.6 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Fork_head PF00250.13 KOS15655.1 - 3.9e-30 103.7 0.0 7.5e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain GATA PF00320.22 KOS15656.1 - 5.4e-16 57.6 6.4 5.4e-16 57.6 4.5 2.1 3 0 0 3 3 3 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KOS15656.1 - 0.013 14.8 1.4 0.026 13.8 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RRN7 PF11781.3 KOS15656.1 - 0.11 12.0 1.0 0.23 11.0 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KOS15656.1 - 0.78 9.3 4.6 0.16 11.5 0.4 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Arf PF00025.16 KOS15657.1 - 1.2e-43 148.3 0.1 2.5e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Clat_adaptor_s PF01217.15 KOS15657.1 - 8.6e-32 109.8 0.8 1.7e-31 108.8 0.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain G-alpha PF00503.15 KOS15657.1 - 6.2e-11 41.6 2.1 1.5e-05 23.8 0.1 2.5 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KOS15657.1 - 3.1e-05 23.8 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS15657.1 - 6.1e-05 22.2 0.2 0.00019 20.6 0.0 1.8 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KOS15657.1 - 8.1e-05 21.9 0.0 0.00018 20.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KOS15657.1 - 0.00034 21.0 0.0 0.00078 19.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KOS15657.1 - 0.0029 17.0 0.0 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 Ras family Fes1 PF08609.5 KOS15658.1 - 6.5e-19 68.2 0.2 1.3e-18 67.2 0.2 1.6 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KOS15658.1 - 0.0011 19.2 4.0 0.064 13.5 0.1 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KOS15658.1 - 0.035 14.1 0.3 11 6.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.18 KOS15658.1 - 0.093 12.5 2.2 8.8 6.3 0.0 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KOS15658.1 - 0.32 11.5 4.2 0.37 11.3 0.1 3.1 3 1 0 3 3 3 0 HEAT-like repeat TFIIE_alpha PF02002.12 KOS15659.1 - 1.6e-11 43.6 0.0 2.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 KOS15659.1 - 0.15 11.4 1.2 0.34 10.2 0.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding 60KD_IMP PF02096.15 KOS15660.1 - 1.3e-41 142.4 5.6 2.1e-41 141.7 3.9 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TMF_DNA_bd PF12329.3 KOS15662.1 - 0.12 12.2 1.6 6 6.7 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding POX PF07526.6 KOS15662.1 - 0.12 12.6 1.9 0.28 11.4 1.3 1.7 1 1 0 1 1 1 0 Associated with HOX DUF4472 PF14739.1 KOS15662.1 - 0.33 11.4 4.7 1.5 9.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) AA_permease PF00324.16 KOS15663.1 - 1e-15 57.0 2.7 1.2e-15 56.8 1.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KOS15663.1 - 0.0015 17.1 3.2 0.0017 16.9 2.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2428 PF10350.4 KOS15664.1 - 6.5e-40 136.7 3.2 1.2e-39 135.9 2.2 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KOS15664.1 - 7.5e-05 22.4 12.3 0.15 12.2 0.2 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KOS15664.1 - 0.00013 22.1 21.2 0.12 12.6 3.4 6.1 3 2 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KOS15664.1 - 0.00056 20.3 8.0 1.4 9.5 0.5 5.2 4 0 0 4 4 4 2 HEAT-like repeat CLASP_N PF12348.3 KOS15664.1 - 0.024 14.0 0.8 0.12 11.7 0.3 2.1 2 0 0 2 2 2 0 CLASP N terminal Adaptin_N PF01602.15 KOS15664.1 - 0.46 8.7 2.6 1 7.6 0.1 2.3 3 0 0 3 3 3 0 Adaptin N terminal region Sec7 PF01369.15 KOS15665.1 - 1.4e-19 70.5 0.0 2.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Pkinase PF00069.20 KOS15666.1 - 4.6e-64 216.0 0.0 6.4e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15666.1 - 1.4e-28 99.6 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KOS15666.1 - 0.027 14.2 0.1 0.15 11.7 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family AAA_11 PF13086.1 KOS15667.1 - 2.6e-63 213.7 0.0 5.4e-63 212.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KOS15667.1 - 9.5e-59 198.1 0.0 1.6e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 KOS15667.1 - 4.5e-20 71.3 3.0 1.2e-19 69.8 2.1 1.5 1 1 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 KOS15667.1 - 2.7e-11 43.0 0.5 2.7e-11 43.0 0.4 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KOS15667.1 - 2.2e-09 37.1 0.1 2.2e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KOS15667.1 - 9.9e-07 28.5 0.1 0.18 11.2 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KOS15667.1 - 3.1e-06 26.6 0.0 0.0016 17.7 0.0 2.3 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KOS15667.1 - 0.00029 21.0 0.1 0.14 12.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KOS15667.1 - 0.0093 15.3 0.0 0.048 13.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain 7tm_2 PF00002.19 KOS15667.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) AAA PF00004.24 KOS15667.1 - 0.036 14.2 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS15667.1 - 0.051 13.5 0.1 0.051 13.5 0.0 3.7 2 1 0 3 3 3 0 AAA ATPase domain Peptidase_M22 PF00814.20 KOS15668.1 - 1.3e-76 257.6 0.0 1.8e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family DUF1681 PF07933.9 KOS15669.1 - 1.3e-49 167.8 0.0 1.5e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SSV1_ORF_D-335 PF07935.6 KOS15669.1 - 0.03 14.0 0.1 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 ORF D-335-like protein NAD_binding_10 PF13460.1 KOS15670.1 - 8.2e-21 74.8 0.1 1.3e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KOS15670.1 - 6.9e-14 51.6 0.0 1.5e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KOS15670.1 - 6.5e-12 44.7 0.0 2.1e-10 39.7 0.0 2.2 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KOS15670.1 - 2.4e-11 43.5 0.1 6.2e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KOS15670.1 - 5.4e-11 41.9 0.0 7.2e-09 34.9 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KOS15670.1 - 1.5e-10 40.4 0.5 5.4e-07 28.7 0.3 3.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KOS15670.1 - 0.00055 19.0 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KOS15670.1 - 0.0069 16.3 0.2 0.081 12.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KOS15670.1 - 0.0097 15.5 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 KR domain DapB_N PF01113.15 KOS15670.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KOS15670.1 - 0.016 15.6 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KOS15670.1 - 0.075 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein tRNA-synt_2b PF00587.20 KOS15671.1 - 1.7e-29 102.6 0.3 4.8e-29 101.1 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KOS15671.1 - 0.039 12.7 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Na_H_Exchanger PF00999.16 KOS15672.1 - 1.3e-60 204.9 21.7 1.6e-60 204.6 15.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_S19e PF01090.14 KOS15673.1 - 5.1e-56 187.9 0.0 5.9e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Nucleoplasmin PF03066.10 KOS15673.1 - 0.1 12.0 6.1 0.12 11.8 4.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Androgen_recep PF02166.11 KOS15673.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Androgen receptor Pho88 PF10032.4 KOS15674.1 - 2.1e-69 232.5 0.1 2.5e-69 232.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) VWA_2 PF13519.1 KOS15675.1 - 1.5e-11 44.7 0.0 3.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KOS15675.1 - 2.7e-07 30.4 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 KOS15675.1 - 3.7e-05 22.8 0.0 5.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A zf-CCCH PF00642.19 KOS15676.1 - 8.7e-09 34.8 2.5 8.7e-09 34.8 1.7 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KOS15676.1 - 4.6e-08 32.9 9.2 8.7e-08 32.0 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS15676.1 - 9.1e-08 31.6 4.8 1.6e-07 30.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS15676.1 - 3.7e-06 26.5 8.1 6.7e-06 25.7 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KOS15676.1 - 8e-06 25.5 8.0 1.4e-05 24.8 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KOS15676.1 - 2.8e-05 23.7 5.0 7.2e-05 22.4 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KOS15676.1 - 0.00014 21.6 7.8 0.00032 20.5 5.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KOS15676.1 - 0.00014 21.4 8.7 0.00028 20.4 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KOS15676.1 - 0.0045 16.4 3.5 0.0081 15.6 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KOS15676.1 - 0.88 9.7 5.3 3.6 7.7 3.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KOS15676.1 - 1.5 8.7 6.1 5.8 6.8 4.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger PI3_PI4_kinase PF00454.22 KOS15677.1 - 1.4e-30 106.4 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Herpes_UL51 PF04540.8 KOS15677.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL51 protein SWIRM PF04433.12 KOS15678.1 - 2.9e-09 36.9 0.0 8.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KOS15678.1 - 6e-09 35.3 6.6 1.1e-08 34.4 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KOS15678.1 - 1.2e-08 34.8 0.0 3.7e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KOS15678.1 - 1.5e-05 25.0 0.0 4.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Acyl-CoA_ox_N PF14749.1 KOS15678.1 - 0.14 12.4 3.8 0.41 10.9 2.7 1.8 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Elf1 PF05129.8 KOS15678.1 - 0.15 11.7 1.0 0.4 10.4 0.7 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like tRNA-synt_1 PF00133.17 KOS15679.1 - 9.4e-225 747.1 0.0 2e-224 746.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS15679.1 - 2.7e-27 95.3 0.0 6.6e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KOS15679.1 - 1.2e-18 66.9 0.8 3.2e-06 26.0 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KOS15679.1 - 0.00022 20.4 0.0 0.0059 15.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Bromodomain PF00439.20 KOS15680.1 - 3e-25 87.9 0.1 5.6e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KOS15680.1 - 1.1e-10 41.4 0.1 2.1e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KOS15680.1 - 3.1e-08 33.5 0.0 8.1e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family OSCP PF00213.13 KOS15681.1 - 3.8e-32 111.5 1.5 5.4e-32 111.0 1.1 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit GWT1 PF06423.7 KOS15681.1 - 9.7e-28 96.9 2.0 2.3e-27 95.7 0.4 2.4 2 0 0 2 2 2 1 GWT1 DUF2231 PF09990.4 KOS15681.1 - 0.044 14.1 0.8 0.044 14.1 0.6 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) PTPA PF03095.10 KOS15682.1 - 8e-108 360.1 0.0 9.4e-108 359.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SAP PF02037.22 KOS15683.1 - 2.5e-11 42.7 1.4 6.5e-11 41.4 1.0 1.8 1 0 0 1 1 1 1 SAP domain CCT_2 PF09425.5 KOS15683.1 - 0.017 14.6 0.2 0.017 14.6 0.2 2.4 2 0 0 2 2 2 0 Divergent CCT motif Tmemb_cc2 PF10267.4 KOS15683.1 - 0.027 13.0 3.3 0.042 12.4 2.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CAF-1_p150 PF11600.3 KOS15683.1 - 2.7 7.3 22.9 4 6.7 15.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Packaging_FI PF14000.1 KOS15683.1 - 5.2 7.2 11.5 2.1 8.5 3.3 2.6 2 1 0 2 2 2 0 DNA packaging protein FI zf-DHHC PF01529.15 KOS15684.1 - 7.6e-34 116.5 0.5 1.5e-31 109.0 0.0 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase ATP11 PF06644.6 KOS15685.1 - 2.7e-76 256.6 5.3 3.1e-76 256.4 3.7 1.0 1 0 0 1 1 1 1 ATP11 protein CAF-1_p150 PF11600.3 KOS15685.1 - 0.002 17.5 25.4 0.002 17.5 17.6 1.8 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2413 PF10310.4 KOS15685.1 - 0.38 9.5 8.2 0.51 9.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) V_ATPase_I PF01496.14 KOS15685.1 - 0.56 8.0 5.5 0.7 7.6 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KOS15685.1 - 0.98 8.4 7.7 1.3 7.9 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KOS15685.1 - 1.1 8.7 5.1 1.8 8.1 3.5 1.4 1 0 0 1 1 1 0 IncA protein Asp-B-Hydro_N PF05279.6 KOS15685.1 - 1.3 8.7 12.3 1.9 8.2 8.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.12 KOS15685.1 - 2 8.1 6.7 3.7 7.2 4.6 1.4 1 0 0 1 1 1 0 DDHD domain OmpH PF03938.9 KOS15685.1 - 7 6.5 16.8 15 5.4 11.5 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MPC PF03650.8 KOS15686.1 - 5e-37 126.5 0.3 5.9e-37 126.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ATG27 PF09451.5 KOS15687.1 - 4.4e-40 137.6 0.3 1.3e-39 136.0 0.1 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Mito_carr PF00153.22 KOS15688.1 - 1.7e-46 155.8 8.9 1.2e-18 66.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps26 PF03643.10 KOS15689.1 - 7.3e-123 408.7 0.6 1e-122 408.2 0.4 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KOS15689.1 - 0.0014 18.5 0.2 0.21 11.4 0.0 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-sulfurylase PF01747.12 KOS15690.1 - 1.4e-86 289.2 0.1 2e-86 288.7 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KOS15690.1 - 6.8e-57 191.5 0.0 1e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KOS15690.1 - 4.2e-52 175.7 0.0 7e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KOS15690.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TPR_11 PF13414.1 KOS15691.1 - 2.8e-29 100.5 8.1 4.3e-09 35.9 0.7 3.7 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KOS15691.1 - 2.6e-23 80.5 4.2 1.5e-05 24.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15691.1 - 2.5e-20 70.6 7.5 0.00031 20.4 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15691.1 - 6.6e-16 58.5 7.4 1.3e-06 28.9 0.1 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15691.1 - 1e-15 57.4 14.3 1.4e-08 34.5 0.0 4.8 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15691.1 - 6.4e-14 51.2 10.4 0.00014 22.1 0.0 5.9 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15691.1 - 1.7e-12 46.4 5.3 0.018 15.2 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15691.1 - 1.7e-12 46.1 2.1 0.025 14.3 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15691.1 - 2.6e-11 43.7 3.4 3.7e-06 27.1 0.9 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KOS15691.1 - 3.2e-11 42.1 12.8 0.0023 17.5 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15691.1 - 1.6e-07 31.3 2.4 1.1 9.8 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KOS15691.1 - 6.9e-07 29.3 1.8 0.014 15.4 0.1 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KOS15691.1 - 5.7e-05 22.9 9.7 0.24 11.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KOS15691.1 - 0.00058 19.9 16.8 0.0048 16.9 1.0 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15691.1 - 0.0072 16.1 10.7 0.62 9.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat DDE_Tnp_ISL3 PF01610.12 KOS15691.1 - 0.074 12.6 0.5 0.16 11.5 0.4 1.6 1 0 0 1 1 1 0 Transposase Fis1_TPR_C PF14853.1 KOS15691.1 - 0.12 12.2 0.3 34 4.4 0.1 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LRR_4 PF12799.2 KOS15692.1 - 5.9e-48 159.8 46.4 3.2e-07 29.7 0.2 13.5 7 4 7 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS15692.1 - 5.2e-44 147.8 49.2 6.7e-08 32.1 0.2 9.4 3 3 4 10 10 10 8 Leucine rich repeat PP2C PF00481.16 KOS15692.1 - 6.3e-39 133.9 0.0 1.2e-38 133.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 KOS15692.1 - 1.8e-25 89.3 0.0 3.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KOS15692.1 - 2e-20 69.6 52.9 0.027 14.4 0.6 17.8 18 1 1 19 19 19 8 Leucine Rich Repeat LRR_7 PF13504.1 KOS15692.1 - 8.3e-08 31.2 53.8 1.5 9.3 0.4 16.5 17 0 0 17 17 17 3 Leucine rich repeat LRR_6 PF13516.1 KOS15692.1 - 1.9e-07 30.4 45.1 6.7 7.1 0.6 14.1 14 2 2 16 16 16 4 Leucine Rich repeat RA PF00788.18 KOS15692.1 - 0.0014 19.0 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 KOS15692.1 - 0.0076 15.8 11.9 0.27 10.7 0.1 4.8 2 1 3 5 5 5 1 Leucine-rich repeat SNase PF00565.12 KOS15693.1 - 5.1e-20 71.7 0.0 1.4e-18 67.1 0.0 2.2 1 1 0 1 1 1 1 Staphylococcal nuclease homologue LRR_8 PF13855.1 KOS15693.1 - 4.9e-12 45.4 0.4 6.5e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KOS15693.1 - 7.5e-09 35.0 0.0 0.018 14.6 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS15693.1 - 0.00098 18.8 3.5 15 6.1 0.0 5.0 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 KOS15693.1 - 0.13 12.5 3.9 92 3.9 0.0 4.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KOS15693.1 - 1.3 9.3 4.9 99 3.4 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat AMP-binding PF00501.23 KOS15694.1 - 8e-224 742.6 7.5 6.8e-84 281.6 0.0 3.6 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KOS15694.1 - 5.6e-66 222.4 28.7 1.9e-21 76.2 0.0 7.4 5 3 0 5 5 5 4 Condensation domain PP-binding PF00550.20 KOS15694.1 - 1.7e-41 140.2 1.2 3.1e-10 40.1 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KOS15694.1 - 7.8e-15 55.5 6.6 1.8e-05 25.5 0.0 5.1 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Nucleocap_ssRNA PF11128.3 KOS15694.1 - 1.9 7.9 0.0 3.8 6.9 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Med12 PF09497.5 KOS15695.1 - 1.1e-19 70.0 0.1 5.8e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KOS15695.1 - 0.073 11.5 1.3 0.16 10.4 0.9 1.4 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain TruB_C PF09142.6 KOS15696.1 - 0.0099 15.4 0.3 0.13 11.9 0.0 2.7 3 0 0 3 3 3 1 tRNA Pseudouridine synthase II, C terminal Metallophos PF00149.23 KOS15698.1 - 1.8e-13 50.3 4.9 7.4e-13 48.3 3.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS15698.1 - 0.00012 21.9 0.1 0.00064 19.5 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CAP_GLY PF01302.20 KOS15699.1 - 4.5e-14 51.9 0.2 6.9e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Filament PF00038.16 KOS15699.1 - 9.1e-07 28.6 35.1 9.1e-07 28.6 24.3 2.9 1 1 2 3 3 3 1 Intermediate filament protein Fez1 PF06818.10 KOS15699.1 - 0.0033 17.4 23.5 0.0033 17.4 16.3 3.6 1 1 2 3 3 3 1 Fez1 Tropomyosin_1 PF12718.2 KOS15699.1 - 2.1 8.1 74.5 0.17 11.7 10.1 4.3 1 1 2 3 3 3 0 Tropomyosin like Allexi_40kDa PF05549.6 KOS15699.1 - 3 7.0 31.7 0.86 8.8 4.6 4.2 1 1 3 4 4 4 0 Allexivirus 40kDa protein Tropomyosin PF00261.15 KOS15699.1 - 4.7 6.2 72.3 0.074 12.1 21.2 3.3 2 1 1 3 3 3 0 Tropomyosin KH_1 PF00013.24 KOS15700.1 - 9.6e-72 236.5 12.0 1.8e-13 49.9 0.0 11.8 11 1 0 11 11 11 8 KH domain KH_3 PF13014.1 KOS15700.1 - 9.1e-42 140.0 16.2 1.2e-08 34.4 0.0 9.5 9 0 0 9 9 9 6 KH domain KH_2 PF07650.12 KOS15700.1 - 4e-11 42.3 6.0 0.27 10.8 0.0 6.6 6 0 0 6 6 6 4 KH domain KH_4 PF13083.1 KOS15700.1 - 0.00066 19.2 5.8 1.8 8.2 0.0 5.5 6 0 0 6 6 6 2 KH domain KH_5 PF13184.1 KOS15700.1 - 0.0018 18.0 0.3 29 4.5 0.0 5.0 5 0 0 5 5 5 0 NusA-like KH domain Siva PF05458.7 KOS15700.1 - 0.022 14.3 0.4 0.5 9.9 0.1 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ZU5 PF00791.15 KOS15700.1 - 0.025 14.2 0.9 19 4.9 0.0 3.9 5 0 0 5 5 5 0 ZU5 domain NIL PF09383.5 KOS15700.1 - 3.7 7.1 8.5 26 4.4 0.0 4.9 5 0 0 5 5 5 0 NIL domain Metallophos PF00149.23 KOS15701.1 - 1.1e-05 24.9 3.7 3.5e-05 23.2 1.1 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase GN3L_Grn1 PF08701.6 KOS15702.1 - 7.4e-23 80.2 12.9 7.4e-23 80.2 8.9 4.0 4 0 0 4 4 3 1 GNL3L/Grn1 putative GTPase Nucleoplasmin PF03066.10 KOS15702.1 - 0.0011 18.4 2.0 0.0011 18.4 1.4 4.2 3 1 0 3 3 2 1 Nucleoplasmin Myc_N PF01056.13 KOS15702.1 - 0.0017 17.6 0.2 0.0017 17.6 0.2 4.2 3 1 0 3 3 2 1 Myc amino-terminal region BUD22 PF09073.5 KOS15702.1 - 0.003 16.6 37.8 0.033 13.2 13.4 3.4 3 0 0 3 3 3 3 BUD22 MMR_HSR1 PF01926.18 KOS15702.1 - 0.0063 16.4 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOA36 PF06524.7 KOS15702.1 - 0.0068 15.7 23.8 0.18 11.0 9.3 2.5 2 0 0 2 2 2 2 NOA36 protein Arf PF00025.16 KOS15702.1 - 0.024 13.8 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KOS15702.1 - 0.042 14.3 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein CbiA PF01656.18 KOS15702.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KOS15702.1 - 0.056 14.2 0.0 0.056 14.2 0.0 3.2 3 2 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 KOS15702.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.8 4 0 0 4 4 4 0 Dynamin family AAA_21 PF13304.1 KOS15702.1 - 0.14 12.0 0.2 2 8.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Sporozoite_P67 PF05642.6 KOS15702.1 - 6 4.5 18.8 3.3 5.4 0.4 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 KOS15703.1 - 3.2e-17 62.2 49.6 7.9e-12 44.5 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Semialdhyde_dhC PF02774.13 KOS15704.1 - 5.4e-43 146.9 0.0 7.4e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KOS15704.1 - 1.1e-26 93.4 0.0 3.2e-26 92.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS15704.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KOS15704.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.1 KOS15704.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 KOS15704.1 - 0.13 11.8 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 KR domain DcpS_C PF11969.3 KOS15705.1 - 1.9e-26 92.5 0.0 3.3e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KOS15705.1 - 4.8e-21 75.2 0.0 8.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 KOS15705.1 - 0.0093 16.4 0.1 0.13 12.8 0.0 2.4 2 1 0 2 2 2 1 HIT domain vATP-synt_AC39 PF01992.11 KOS15706.1 - 3.9e-97 325.3 0.0 4.4e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Cyclin_C PF02984.14 KOS15706.1 - 0.054 13.4 0.1 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Acyl_CoA_thio PF02551.10 KOS15706.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase PS_Dcarbxylase PF02666.10 KOS15707.1 - 7.5e-48 162.5 0.0 1.3e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KOS15707.1 - 2.7e-15 55.9 0.1 6.5e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 KOS15707.1 - 7.5e-05 21.7 0.0 0.00018 20.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KOS15707.1 - 0.00029 20.9 0.3 0.00072 19.6 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS15707.1 - 0.0014 18.3 0.2 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KOS15707.1 - 0.053 12.8 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 EF hand GAD-like PF08887.6 KOS15707.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain ILVD_EDD PF00920.16 KOS15708.1 - 3.8e-193 642.6 0.2 4.3e-193 642.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Nefa_Nip30_N PF10187.4 KOS15709.1 - 2.6e-24 85.3 10.2 2.6e-24 85.3 7.1 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Pol_alpha_B_N PF08418.5 KOS15709.1 - 0.55 9.7 7.5 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1423 PF07227.6 KOS15709.1 - 4.8 5.7 5.7 5.9 5.4 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) GrpE PF01025.14 KOS15709.1 - 6.5 6.2 8.7 5.6 6.4 4.0 2.0 2 0 0 2 2 2 0 GrpE Hydrolase_like PF13242.1 KOS15710.1 - 3.4e-21 74.7 0.0 8.6e-21 73.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KOS15710.1 - 6e-20 71.0 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS15710.1 - 3.8e-05 23.9 0.1 0.00067 19.9 0.0 2.8 4 0 0 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KOS15710.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HA2 PF04408.18 KOS15711.1 - 1.4e-18 66.7 0.1 6.2e-18 64.6 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS15711.1 - 3e-13 49.4 0.0 2.3e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KOS15711.1 - 1e-07 31.7 0.0 3.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KOS15711.1 - 4e-07 29.6 0.0 8.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KOS15711.1 - 8.8e-07 29.1 0.6 3.4e-06 27.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 KOS15711.1 - 0.015 14.4 0.0 0.037 13.1 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KOS15711.1 - 0.04 14.2 15.9 0.08 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KOS15711.1 - 0.089 11.9 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Hpt PF01627.18 KOS15712.1 - 5.2e-11 42.4 0.2 9.7e-11 41.5 0.0 1.5 2 0 0 2 2 2 1 Hpt domain GrpE PF01025.14 KOS15712.1 - 0.034 13.7 0.5 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 GrpE DUF3919 PF13057.1 KOS15712.1 - 0.039 13.4 0.1 2.4 7.5 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3919) Macoilin PF09726.4 KOS15712.1 - 0.042 12.1 0.0 0.054 11.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein ERG4_ERG24 PF01222.12 KOS15713.1 - 1e-149 498.7 10.0 1.2e-149 498.5 7.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KOS15713.1 - 3.9e-07 29.6 0.5 1e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KOS15713.1 - 0.0005 20.1 4.0 0.00052 20.0 0.0 3.1 4 1 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 KOS15713.1 - 0.061 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2462 PF09495.5 KOS15714.1 - 8.7e-11 42.4 9.7 1e-10 42.2 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Spore_SspJ PF09575.5 KOS15714.1 - 0.13 12.5 2.4 0.42 10.8 1.7 2.0 1 1 0 1 1 1 0 Small spore protein J (Spore_SspJ) Fcf2 PF08698.6 KOS15716.1 - 6e-15 55.0 0.1 2.5e-13 49.8 0.0 2.9 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing WD40 PF00400.27 KOS15718.1 - 8.4e-08 31.8 3.6 0.0069 16.2 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Mit_KHE1 PF10173.4 KOS15719.1 - 8.8e-45 152.8 1.2 1.2e-44 152.4 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related LysE PF01810.13 KOS15719.1 - 0.13 11.5 0.3 8.4 5.6 0.0 2.2 2 0 0 2 2 2 0 LysE type translocator Peptidase_S28 PF05577.7 KOS15720.1 - 2.8e-38 131.6 0.0 4.7e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 SET PF00856.23 KOS15721.1 - 5.9e-09 36.4 0.0 2e-06 28.1 0.0 3.1 2 1 0 2 2 2 1 SET domain dCMP_cyt_deam_1 PF00383.17 KOS15721.1 - 2.5e-07 30.2 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HR1 PF02185.11 KOS15722.1 - 1.1e-20 73.0 11.1 1.4e-10 40.7 3.3 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KOS15722.1 - 1.9e-18 65.8 28.8 2.7e-09 36.5 6.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Uds1 PF15456.1 KOS15722.1 - 1.9 8.4 11.3 2.6 8.0 2.8 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Occludin_ELL PF07303.8 KOS15722.1 - 3.2 8.5 9.7 22 5.8 2.7 2.4 2 0 0 2 2 2 0 Occludin homology domain Peptidase_S28 PF05577.7 KOS15723.1 - 2.1e-34 118.8 0.3 6.3e-34 117.2 0.2 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DEC-1_N PF04625.8 KOS15723.1 - 0.23 10.1 10.2 0.4 9.3 7.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RAP1 PF07218.6 KOS15723.1 - 3 5.8 8.2 4.2 5.3 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S17 PF00366.15 KOS15724.1 - 1.3e-27 95.6 2.0 1.8e-27 95.1 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 CTNNBL PF08216.6 KOS15725.1 - 3.3e-27 94.1 2.7 4.2e-27 93.8 0.4 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear ACT PF01842.20 KOS15725.1 - 0.77 9.3 7.5 0.062 12.7 0.4 2.8 4 0 0 4 4 4 0 ACT domain Aminotran_1_2 PF00155.16 KOS15726.1 - 1.7e-36 125.9 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KOS15726.1 - 0.0006 18.2 0.0 0.0011 17.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4390 PF14334.1 KOS15726.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) LRR_6 PF13516.1 KOS15727.1 - 1e-12 46.7 0.0 5.5 7.3 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 KOS15727.1 - 5.6e-11 40.9 2.4 2 8.7 0.0 8.5 8 1 0 8 8 8 2 Leucine Rich Repeat F-box-like PF12937.2 KOS15727.1 - 6.9e-11 41.7 6.9 8.8e-11 41.3 3.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KOS15727.1 - 8.3e-09 34.8 0.0 0.18 11.4 0.0 5.6 2 1 4 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KOS15727.1 - 1.7e-08 34.0 0.3 0.36 10.6 0.0 5.8 3 1 0 5 5 5 2 Leucine rich repeat F-box PF00646.28 KOS15727.1 - 0.00074 19.1 1.0 0.0035 16.9 0.7 2.2 1 0 0 1 1 1 1 F-box domain LRR_7 PF13504.1 KOS15727.1 - 0.0012 18.7 9.4 14 6.4 0.0 7.4 8 0 0 8 8 8 1 Leucine rich repeat Ste50p-SAM PF09235.5 KOS15727.1 - 0.21 11.6 2.2 28 4.8 0.1 3.9 3 1 1 4 4 4 0 Ste50p, sterile alpha motif DEAD PF00270.24 KOS15728.1 - 7.8e-39 132.8 0.0 1.4e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS15728.1 - 1.7e-20 72.6 0.0 4e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KOS15728.1 - 1.1e-17 63.2 0.0 2.5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KOS15728.1 - 1e-05 25.4 0.1 2.6e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 KOS15728.1 - 0.19 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) GTP_EFTU PF00009.22 KOS15729.1 - 2.3e-52 177.1 0.0 4.2e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KOS15729.1 - 1.1e-13 50.8 0.0 4.2e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 KOS15729.1 - 9e-08 31.8 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KOS15729.1 - 5.7e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KOS15729.1 - 5.8e-06 25.8 0.0 1.8e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KOS15729.1 - 7.4e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS15729.1 - 0.057 13.2 0.1 2.4 7.9 0.1 2.6 1 1 0 1 1 1 0 Dynamin family Ras PF00071.17 KOS15729.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.7 1 0 0 1 1 1 0 Ras family Miro PF08477.8 KOS15729.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Hydrolase_like2 PF13246.1 KOS15730.1 - 2.6e-12 46.5 0.0 7e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KOS15730.1 - 1.6e-11 45.0 0.6 2e-05 25.1 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS15730.1 - 1.6e-11 44.7 0.0 6.1e-11 42.8 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KOS15730.1 - 5.2e-11 42.0 0.0 1.9e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KOS15730.1 - 8.1e-05 22.3 0.2 0.0041 16.7 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Peptidase_C14 PF00656.17 KOS15731.1 - 2.9e-62 210.6 0.0 3.4e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Abhydrolase_5 PF12695.2 KOS15732.1 - 1.9e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS15732.1 - 1.3e-05 25.2 0.1 2.3e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS15732.1 - 0.012 15.1 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.16 KOS15732.1 - 0.062 12.5 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Endosulfine PF04667.12 KOS15733.1 - 5.2e-22 77.6 0.1 7.8e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region CK_II_beta PF01214.13 KOS15734.1 - 5.7e-77 257.3 0.0 7.1e-77 257.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Tom22 PF04281.8 KOS15735.1 - 1.3e-43 147.8 0.8 1.5e-43 147.6 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Pox_Ag35 PF03286.9 KOS15735.1 - 0.11 12.0 2.7 0.15 11.5 1.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTS_EIIA_1 PF00358.15 KOS15735.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Nop14 PF04147.7 KOS15735.1 - 2.5 5.9 4.6 2.8 5.7 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family EPL1 PF10513.4 KOS15736.1 - 9e-26 91.0 1.0 9e-26 91.0 0.7 4.5 4 2 1 5 5 5 1 Enhancer of polycomb-like FAM176 PF14851.1 KOS15736.1 - 0.85 9.2 4.5 3.7 7.2 3.1 2.1 1 0 0 1 1 1 0 FAM176 family RhoGAP PF00620.22 KOS15737.1 - 3.5e-07 29.9 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KOS15737.1 - 2.2e-05 24.5 0.2 6.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Abhydrolase_6 PF12697.2 KOS15738.1 - 1.7e-06 28.1 0.6 2.5e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS15738.1 - 3.4e-06 26.8 0.0 5.8e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS15738.1 - 0.012 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PhoPQ_related PF10142.4 KOS15738.1 - 0.026 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Hist_deacetyl PF00850.14 KOS15739.1 - 2.8e-59 200.9 1.5 4.1e-59 200.4 1.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Trs65 PF12735.2 KOS15740.1 - 1.6e-06 27.7 0.0 0.016 14.4 0.0 2.7 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 POP1 PF06978.6 KOS15741.1 - 1.4e-39 135.6 17.1 3.1e-38 131.3 11.9 2.3 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KOS15741.1 - 4.9e-16 58.3 0.0 1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 KOS15741.1 - 0.002 17.5 0.1 0.0088 15.4 0.0 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Sugar_tr PF00083.19 KOS15742.1 - 2.1e-31 109.0 24.0 1.4e-30 106.2 16.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS15742.1 - 3.3e-29 101.7 32.3 3.3e-29 101.7 22.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KOS15742.1 - 0.00016 20.0 7.8 0.047 11.8 0.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KOS15742.1 - 0.001 18.8 6.6 0.18 11.5 0.8 2.9 2 1 0 2 2 2 2 MFS_1 like family ATG22 PF11700.3 KOS15742.1 - 0.0027 16.2 6.5 0.0027 16.2 4.5 2.8 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like eIF-3c_N PF05470.7 KOS15743.1 - 5.9e-178 592.6 13.4 5.9e-178 592.6 9.3 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KOS15743.1 - 2.4e-13 50.3 0.9 8.3e-13 48.5 0.1 2.5 2 1 0 2 2 2 1 PCI domain Sigma70_r4 PF04545.11 KOS15743.1 - 0.0073 15.5 0.0 0.047 13.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 DUF4208 PF13907.1 KOS15743.1 - 0.47 10.7 5.0 17 5.6 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) zf-CCCH PF00642.19 KOS15744.1 - 4.3e-13 48.6 13.3 1.7e-06 27.5 2.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KOS15744.1 - 8.3e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS15744.1 - 0.00028 20.4 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15744.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-5_eIF-2B PF01873.12 KOS15745.1 - 2.9e-46 156.1 0.5 4.5e-46 155.5 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 KOS15745.1 - 0.0084 15.4 0.1 0.017 14.4 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding DUF1754 PF08555.5 KOS15745.1 - 0.53 10.9 15.3 0.95 10.0 3.4 2.4 1 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Arc_trans_TRASH PF08394.5 KOS15745.1 - 1.1 9.4 5.9 1.3 9.2 0.1 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain Cyclin_N PF00134.18 KOS15746.1 - 4.1e-08 32.8 0.0 8.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS15746.1 - 0.012 15.5 6.1 0.11 12.4 0.1 2.9 3 0 0 3 3 3 0 Cyclin, C-terminal domain BPL_LplA_LipB PF03099.14 KOS15746.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family TFIIB PF00382.14 KOS15746.1 - 0.15 11.8 0.5 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat ATP-synt PF00231.14 KOS15747.1 - 3e-69 233.5 1.1 3.5e-69 233.3 0.8 1.0 1 0 0 1 1 1 1 ATP synthase CPSase_sm_chain PF00988.17 KOS15748.1 - 4.8e-45 152.2 0.0 7.3e-45 151.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KOS15748.1 - 2.6e-36 124.8 0.0 3.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KOS15748.1 - 0.00011 21.7 0.9 0.0015 17.9 0.5 2.5 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 KOS15748.1 - 0.056 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_5 PF13507.1 KOS15749.1 - 5.2e-93 310.6 0.0 8.6e-93 309.9 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KOS15749.1 - 1.6e-45 154.8 0.2 8.4e-27 94.0 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KOS15749.1 - 1.6e-21 76.3 0.1 7e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain zf-C2H2_jaz PF12171.3 KOS15750.1 - 1.1e-06 28.6 0.5 2.2e-06 27.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS15750.1 - 3.7e-06 26.9 1.3 8.7e-06 25.7 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KOS15750.1 - 0.075 12.5 1.3 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF1674 PF07896.7 KOS15751.1 - 4.2e-13 49.2 2.4 7e-13 48.5 1.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) HDV_ag PF01517.13 KOS15751.1 - 0.025 14.2 0.5 0.033 13.8 0.3 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Isochorismatase PF00857.15 KOS15752.1 - 2.2e-24 86.3 0.4 7.4e-24 84.6 0.2 2.1 1 1 0 1 1 1 1 Isochorismatase family UPAR_LY6 PF00021.16 KOS15752.1 - 0.086 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain DUF1168 PF06658.7 KOS15754.1 - 2.9e-32 111.1 8.1 2.9e-32 111.1 5.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Thioredoxin_4 PF13462.1 KOS15754.1 - 0.022 14.7 0.6 0.031 14.2 0.4 1.2 1 0 0 1 1 1 0 Thioredoxin OstA PF03968.9 KOS15754.1 - 0.092 12.7 2.0 0.16 11.9 1.4 1.4 1 0 0 1 1 1 0 OstA-like protein MRP-L46 PF11788.3 KOS15754.1 - 2.7 8.7 8.6 1.8 9.2 3.1 2.1 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 DDHD PF02862.12 KOS15754.1 - 2.7 7.7 5.7 3.3 7.4 3.9 1.3 1 1 0 1 1 1 0 DDHD domain GTP_EFTU PF00009.22 KOS15756.1 - 9.3e-57 191.5 0.1 1.7e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KOS15756.1 - 1e-36 125.1 0.0 2.7e-36 123.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 KOS15756.1 - 6.1e-31 106.0 0.0 1.4e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KOS15756.1 - 4.8e-23 80.8 0.0 1.3e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KOS15756.1 - 1e-12 47.9 0.4 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 YqjK PF13997.1 KOS15756.1 - 4.9 7.3 5.9 1.5 9.0 1.6 1.9 2 0 0 2 2 2 0 YqjK-like protein SF3b1 PF08920.5 KOS15757.1 - 7.1e-21 74.7 13.2 1.8e-16 60.5 0.0 3.7 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KOS15757.1 - 2.9e-20 72.3 11.9 3.4e-06 27.2 0.1 8.4 6 2 4 10 10 10 5 HEAT repeats HEAT PF02985.17 KOS15757.1 - 3.2e-13 48.5 13.2 0.064 13.3 0.0 11.1 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 KOS15757.1 - 4.3e-12 46.1 10.0 0.024 15.1 0.0 9.3 7 3 2 9 9 9 3 HEAT-like repeat Adaptin_N PF01602.15 KOS15757.1 - 2.3e-09 36.1 0.4 0.036 12.3 0.2 3.9 2 2 2 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KOS15757.1 - 3.6e-06 27.2 0.9 4 7.8 0.0 5.7 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 KOS15757.1 - 0.0002 20.7 1.8 13 5.0 0.0 5.2 4 1 1 5 5 5 1 NUC173 domain CLASP_N PF12348.3 KOS15757.1 - 0.00021 20.7 4.9 0.29 10.4 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal Arm PF00514.18 KOS15757.1 - 0.0043 16.8 0.8 21 5.1 0.0 5.4 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 KOS15757.1 - 0.034 13.7 3.2 0.31 10.6 0.0 3.4 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Dopey_N PF04118.9 KOS15757.1 - 0.047 12.4 0.4 0.48 9.1 0.0 2.6 3 0 0 3 3 3 0 Dopey, N-terminal SMC_N PF02463.14 KOS15758.1 - 4.2e-68 228.8 0.0 8.6e-68 227.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KOS15758.1 - 4.4e-21 75.0 1.3 1.4e-19 70.2 0.4 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KOS15758.1 - 8.8e-14 52.1 2.2 1.6e-06 28.2 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KOS15758.1 - 8.6e-12 45.8 25.4 8.6e-12 45.8 17.6 5.9 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KOS15758.1 - 1.7e-05 24.0 0.3 7.3e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KOS15758.1 - 2.8e-05 23.5 0.0 8e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 KOS15758.1 - 0.0055 15.9 8.4 0.0055 15.9 5.8 7.1 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 KOS15758.1 - 0.48 10.7 0.0 0.37 11.1 0.0 5.3 4 2 0 4 4 4 0 ABC transporter Ribosomal_S2 PF00318.15 KOS15759.1 - 8.2e-45 152.6 0.0 8.1e-23 80.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Pyr_redox_3 PF13738.1 KOS15760.1 - 6.3e-05 23.1 0.1 0.015 15.3 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KOS15760.1 - 0.001 18.8 0.6 0.1 12.4 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS15760.1 - 0.0036 17.1 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS15760.1 - 0.021 15.2 0.3 0.85 10.0 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS15760.1 - 0.022 14.7 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH PF00725.17 KOS15760.1 - 0.042 14.2 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain XFP_N PF09364.5 KOS15760.1 - 0.082 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Pkinase PF00069.20 KOS15761.1 - 7e-53 179.4 0.0 9.2e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15761.1 - 2.3e-36 125.1 0.0 7.1e-35 120.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15761.1 - 1.1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS15761.1 - 0.0089 15.7 0.0 0.068 12.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2076 PF09849.4 KOS15762.1 - 6.9e-09 36.1 4.9 7.9e-09 35.9 3.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KOS15762.1 - 0.0001 22.1 6.5 0.00014 21.6 4.5 1.2 1 0 0 1 1 1 1 CHCH domain Succ_CoA_lig PF13607.1 KOS15762.1 - 0.19 11.3 0.8 0.53 9.8 0.0 2.0 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain DUF605 PF04652.11 KOS15762.1 - 6.1 6.1 8.6 7.6 5.8 6.0 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_L15e PF00827.12 KOS15763.1 - 3.7e-92 307.1 10.9 4.3e-92 306.9 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 IFP_35_N PF07334.8 KOS15764.1 - 0.0061 16.5 0.1 0.67 9.9 0.0 2.1 2 0 0 2 2 2 2 Interferon-induced 35 kDa protein (IFP 35) N-terminus IncA PF04156.9 KOS15764.1 - 0.025 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 IncA protein Clr5 PF14420.1 KOS15764.1 - 0.11 12.4 0.6 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Clr5 domain PspB PF06667.7 KOS15764.1 - 0.54 10.2 4.5 2.5 8.1 0.7 2.2 1 1 1 2 2 2 0 Phage shock protein B Med21 PF11221.3 KOS15765.1 - 1.4e-12 47.8 8.4 2.2e-12 47.1 5.8 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 KOS15765.1 - 0.002 17.3 5.1 0.0028 16.8 3.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding GAT PF03127.9 KOS15765.1 - 0.014 15.3 3.5 0.019 14.9 1.9 1.7 1 1 0 1 1 1 0 GAT domain Phage_GP20 PF06810.6 KOS15765.1 - 0.02 14.3 4.4 0.033 13.6 3.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 AAA_13 PF13166.1 KOS15765.1 - 0.027 12.9 5.0 0.032 12.6 3.5 1.0 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KOS15765.1 - 0.068 12.9 4.4 0.13 12.0 3.1 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF3647 PF12363.3 KOS15765.1 - 0.076 13.1 2.4 16 5.6 0.0 2.8 1 1 0 2 2 2 0 Phage protein VCX_VCY PF15231.1 KOS15765.1 - 0.18 12.2 2.1 0.28 11.6 1.4 1.4 1 1 0 1 1 1 0 Variable charge X/Y family YicC_N PF03755.8 KOS15765.1 - 0.18 11.7 5.4 0.22 11.4 3.5 1.3 1 1 0 1 1 1 0 YicC-like family, N-terminal region DUF2203 PF09969.4 KOS15765.1 - 0.29 11.3 1.7 0.54 10.4 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HisKA PF00512.20 KOS15765.1 - 0.3 11.1 3.2 0.31 11.0 0.2 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TBPIP PF07106.8 KOS15765.1 - 0.4 10.2 4.5 0.28 10.7 1.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KOS15765.1 - 0.74 9.3 8.3 0.88 9.1 5.8 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KOS15765.1 - 0.83 8.6 5.7 0.85 8.6 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cofilin_ADF PF00241.15 KOS15766.1 - 6.7e-44 148.8 0.6 7.7e-44 148.6 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Arv1 PF04161.8 KOS15769.1 - 1.5e-20 74.0 0.0 2.4e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 Arv1-like family TPR_11 PF13414.1 KOS15770.1 - 2.7e-20 71.7 18.9 1.5e-13 50.1 5.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KOS15770.1 - 3.6e-12 45.3 11.3 3.9e-08 32.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15770.1 - 5.1e-10 38.4 13.3 8e-06 25.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15770.1 - 1.4e-07 31.9 7.7 3.5e-05 24.3 1.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15770.1 - 1.5e-07 31.2 8.4 1.2e-05 25.1 1.5 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15770.1 - 3.2e-05 23.4 6.8 0.0057 16.3 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15770.1 - 0.00013 22.3 10.4 0.00034 20.9 0.8 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS15770.1 - 0.00017 21.6 7.8 0.0044 17.1 0.3 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KOS15770.1 - 0.00035 20.1 7.8 0.00079 19.0 0.4 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KOS15770.1 - 0.00053 18.8 0.2 0.00075 18.3 0.1 1.3 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KOS15770.1 - 0.00071 19.8 16.7 0.0071 16.6 3.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15770.1 - 0.0014 18.6 6.4 0.14 12.4 0.2 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KOS15770.1 - 0.0034 17.7 12.2 0.15 12.6 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KOS15770.1 - 0.0094 15.8 5.8 0.29 11.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KOS15770.1 - 0.01 16.1 0.9 7.9 7.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15770.1 - 0.017 14.9 5.8 0.08 12.8 2.5 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 KOS15770.1 - 0.039 13.8 4.7 0.052 13.4 0.4 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RRM_1 PF00076.17 KOS15771.1 - 1.8e-09 37.0 0.0 6.1e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15771.1 - 1.9e-08 34.0 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15771.1 - 6.7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 KOS15771.1 - 0.18 12.2 2.2 0.31 11.4 1.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hydro_16 PF00722.16 KOS15772.1 - 5.3e-07 29.1 0.0 9.3e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 CcmD PF04995.9 KOS15773.1 - 0.54 10.0 5.4 0.1 12.3 0.7 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PHD PF00628.24 KOS15774.1 - 8.8e-07 28.5 7.1 1.7e-06 27.6 4.9 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KOS15774.1 - 0.00054 19.6 3.5 0.0017 18.0 2.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 WHIM2 PF15613.1 KOS15774.1 - 0.00076 19.3 0.7 0.0016 18.2 0.5 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 DUF4206 PF13901.1 KOS15774.1 - 0.043 13.3 2.4 0.076 12.5 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) DDT PF02791.12 KOS15774.1 - 0.27 11.0 0.8 0.48 10.2 0.5 1.3 1 0 0 1 1 1 0 DDT domain Tyr-DNA_phospho PF06087.7 KOS15776.1 - 1.1e-10 40.7 0.0 1.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase TFIIE_beta PF02186.10 KOS15776.1 - 2.4e-05 24.2 0.2 5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain DHOase PF12890.2 KOS15776.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Dihydro-orotase-like Sas10 PF09368.5 KOS15777.1 - 8.5e-26 89.9 5.0 8.5e-26 89.9 3.5 2.3 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KOS15777.1 - 2.9e-07 30.5 0.2 1.2e-06 28.6 0.1 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RRM_6 PF14259.1 KOS15778.1 - 2.4e-44 149.1 0.0 1.9e-19 69.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS15778.1 - 2.8e-39 132.6 0.0 3.4e-16 58.6 0.0 5.1 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15778.1 - 7.5e-16 57.7 0.0 7e-09 35.4 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KOS15778.1 - 1.4e-09 37.5 0.0 0.0067 16.1 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KOS15778.1 - 0.13 11.9 0.0 1.8 8.3 0.0 2.8 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CPSF_A PF03178.10 KOS15779.1 - 1.1e-35 123.2 0.0 7.7e-35 120.5 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KOS15779.1 - 1e-11 43.7 0.0 1.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Plasmodium_HRP PF05403.6 KOS15780.1 - 4.1e-06 26.5 21.5 4.1e-06 26.5 14.9 3.4 3 1 0 3 3 3 1 Plasmodium histidine-rich protein (HRPII/III) WD40 PF00400.27 KOS15781.1 - 6.6e-15 54.3 12.0 5.3e-07 29.2 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Rax2 PF12768.2 KOS15781.1 - 0.0028 16.8 0.1 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity FA_desaturase PF00487.19 KOS15782.1 - 5.1e-24 85.1 23.6 1e-23 84.1 16.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase IF-2B PF01008.12 KOS15783.1 - 2.7e-58 197.1 0.0 3.3e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DBR1 PF05011.8 KOS15784.1 - 3.2e-15 56.2 0.3 7.8e-15 55.0 0.2 1.6 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KOS15784.1 - 5.7e-10 38.9 0.0 9.7e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS15784.1 - 2.1e-06 27.6 0.0 4.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NpwBP PF12622.2 KOS15785.1 - 1.9e-16 60.2 7.3 1.9e-16 60.2 5.0 3.1 1 1 2 3 3 3 1 mRNA biogenesis factor TFIIE-A_C-term PF11521.3 KOS15785.1 - 0.18 11.7 3.4 0.39 10.6 2.4 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PAT1 PF09770.4 KOS15785.1 - 7.2 4.7 9.0 8 4.5 6.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GRAM PF02893.15 KOS15786.1 - 8.4e-19 66.8 0.0 2e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Cyt-b5 PF00173.23 KOS15787.1 - 1.4e-11 44.0 0.0 1.6e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sel1 PF08238.7 KOS15788.1 - 5.6e-33 112.6 23.4 0.00011 22.6 1.3 8.4 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 KOS15788.1 - 0.25 11.8 1.8 7.1 7.3 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat SRP40_C PF05022.7 KOS15789.1 - 2.1e-29 101.8 2.6 2.1e-29 101.8 1.8 2.4 2 1 0 2 2 1 1 SRP40, C-terminal domain GAGA_bind PF06217.7 KOS15789.1 - 0.015 15.2 5.0 0.019 14.9 3.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 KOS15789.1 - 0.037 14.0 10.7 0.072 13.1 7.4 1.6 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 KOS15789.1 - 0.049 12.9 12.6 0.09 12.1 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RdRP PF05183.7 KOS15789.1 - 0.068 11.8 2.3 0.096 11.3 1.6 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Paramyxo_ncap PF00973.14 KOS15789.1 - 0.21 10.2 2.4 0.28 9.8 1.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDHD PF02862.12 KOS15789.1 - 0.24 11.1 4.8 0.39 10.4 3.3 1.4 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 KOS15789.1 - 0.25 10.0 10.6 0.33 9.6 7.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 KOS15789.1 - 0.36 8.8 5.0 0.36 8.8 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TP53IP5 PF15331.1 KOS15789.1 - 0.36 10.7 9.0 0.52 10.1 6.3 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BLVR PF06375.6 KOS15789.1 - 0.39 10.5 16.6 0.061 13.1 8.2 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 KOS15789.1 - 0.48 9.5 12.0 0.84 8.7 8.3 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ycf1 PF05758.7 KOS15789.1 - 0.58 7.8 8.2 0.64 7.6 5.7 1.1 1 0 0 1 1 1 0 Ycf1 MCPVI PF02993.9 KOS15789.1 - 0.63 10.1 6.7 0.79 9.8 4.6 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF4448 PF14610.1 KOS15789.1 - 4.2 6.8 5.5 7.6 5.9 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3987 PF13148.1 KOS15789.1 - 7.5 5.0 13.7 11 4.4 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.5 KOS15789.1 - 7.8 6.2 14.1 0.52 10.0 6.2 1.7 2 0 0 2 2 1 0 Peptidase family S49 N-terminal DUF935 PF06074.7 KOS15789.1 - 8.4 4.9 11.1 8.7 4.9 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF935) adh_short PF00106.20 KOS15790.1 - 4.9e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Trypan_PARP PF05887.6 KOS15790.1 - 0.004 16.9 32.9 0.004 16.9 22.8 4.8 4 2 0 5 5 5 1 Procyclic acidic repetitive protein (PARP) DUF4366 PF14283.1 KOS15790.1 - 0.12 11.7 0.3 0.41 10.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EST1_DNA_bind PF10373.4 KOS15791.1 - 0.00018 20.8 0.3 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain HSP90 PF00183.13 KOS15792.1 - 3.7e-252 837.4 29.8 4.7e-252 837.1 20.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KOS15792.1 - 1.5e-11 44.0 0.0 3.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KOS15792.1 - 2.7e-11 43.2 0.2 2.7e-11 43.2 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Adaptin_N PF01602.15 KOS15793.1 - 7.1e-89 298.5 6.4 1.1e-88 297.8 4.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KOS15793.1 - 3.6e-63 211.0 0.0 1e-62 209.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KOS15793.1 - 1.1e-60 203.3 0.2 2.8e-60 202.0 0.2 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KOS15793.1 - 1.4e-10 41.2 6.9 0.0005 20.3 0.0 5.1 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KOS15793.1 - 7.4e-08 32.4 1.8 0.031 14.1 0.0 4.9 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KOS15793.1 - 8.7e-06 25.4 0.4 0.11 12.6 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KOS15793.1 - 0.011 16.1 3.5 16 6.1 0.0 5.1 3 2 2 5 5 5 0 HEAT-like repeat CLASP_N PF12348.3 KOS15793.1 - 0.026 13.9 1.6 0.93 8.8 0.1 3.2 2 2 0 2 2 2 0 CLASP N terminal ParcG PF10274.4 KOS15793.1 - 0.038 13.8 4.9 0.076 12.9 0.0 3.2 2 1 0 3 3 3 0 Parkin co-regulated protein Arm PF00514.18 KOS15793.1 - 0.08 12.7 0.6 2.5 8.0 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SH3_3 PF08239.6 KOS15795.1 - 0.028 14.5 1.1 0.14 12.3 0.8 2.2 1 0 0 1 1 1 0 Bacterial SH3 domain RRM_1 PF00076.17 KOS15796.1 - 1.7e-09 37.1 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15796.1 - 1.9e-08 34.1 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15796.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_int_end_N2 PF12928.2 KOS15798.1 - 1.1e-18 66.4 0.0 2.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KOS15798.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Lipase_GDSL PF00657.17 KOS15799.1 - 5.6e-20 72.1 2.1 8e-20 71.6 1.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KOS15799.1 - 1.1e-07 32.1 0.6 2e-07 31.3 0.4 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Dor1 PF04124.7 KOS15800.1 - 2.6e-13 49.1 4.5 4.7e-13 48.3 3.1 1.6 1 1 0 1 1 1 1 Dor1-like family PHA_synth_III_E PF09712.5 KOS15800.1 - 0.37 10.1 5.1 0.077 12.3 0.3 2.1 2 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Lipase_GDSL PF00657.17 KOS15801.1 - 6e-20 72.0 0.2 7.7e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KOS15801.1 - 3.4e-10 40.3 2.6 5.9e-10 39.5 1.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lact_bio_phlase PF09508.5 KOS15801.1 - 0.14 9.7 0.0 0.18 9.4 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase FimP PF09766.4 KOS15802.1 - 2.6e-07 30.0 13.2 6.3e-07 28.7 9.1 1.5 1 1 0 1 1 1 1 Fms-interacting protein DUF2630 PF10944.3 KOS15802.1 - 0.012 15.6 5.3 0.012 15.6 3.7 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2630) Oxidored_nitro PF00148.14 KOS15802.1 - 0.02 13.5 0.5 0.025 13.2 0.3 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TMF_TATA_bd PF12325.3 KOS15802.1 - 0.046 13.4 10.1 0.025 14.2 4.7 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_27 PF13514.1 KOS15802.1 - 0.086 10.5 17.2 0.38 8.3 11.8 1.8 1 1 0 1 1 1 0 AAA domain SpaB_C PF14028.1 KOS15802.1 - 0.13 11.8 12.0 0.15 11.5 8.3 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain DUF4446 PF14584.1 KOS15802.1 - 0.17 11.6 4.2 6.2 6.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) EzrA PF06160.7 KOS15802.1 - 0.26 9.4 9.1 0.31 9.1 5.8 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sulfatase_C PF14707.1 KOS15802.1 - 0.82 9.9 5.7 0.99 9.7 1.0 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF3508 PF12018.3 KOS15802.1 - 1.1 8.1 6.4 1.5 7.7 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) APG6 PF04111.7 KOS15802.1 - 1.3 7.9 12.9 0.76 8.7 7.4 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KOS15802.1 - 1.6 8.8 6.4 1.4 9.0 3.2 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.7 KOS15802.1 - 1.8 6.8 15.8 2.3 6.5 10.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 KOS15802.1 - 2.8 7.8 12.7 1 9.2 6.8 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaF PF07309.6 KOS15802.1 - 8.2 6.3 12.0 8.6 6.2 1.4 2.3 2 0 0 2 2 2 0 Flagellar protein FlaF DUF972 PF06156.8 KOS15802.1 - 9.7 6.6 8.9 11 6.4 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2372 PF10178.4 KOS15803.1 - 0.14 12.3 0.1 0.59 10.2 0.0 2.1 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Pkinase PF00069.20 KOS15804.1 - 6.9e-75 251.5 0.0 9.8e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15804.1 - 2.5e-35 121.8 0.0 3.6e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15804.1 - 1.5e-05 24.1 0.0 3.3e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Tubulin PF00091.20 KOS15805.1 - 6.1e-72 241.9 0.0 1.2e-71 240.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KOS15805.1 - 4.3e-48 162.5 0.3 6.7e-48 161.8 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KOS15805.1 - 9.6e-07 28.8 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KOS15805.1 - 0.00057 19.4 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain BTB_2 PF02214.17 KOS15806.1 - 0.0017 18.5 0.0 0.049 13.8 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Saccharop_dh PF03435.13 KOS15807.1 - 2e-103 346.3 0.0 2.8e-103 345.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 KOS15807.1 - 6.3e-89 297.1 0.0 2.1e-88 295.4 0.0 1.8 2 0 0 2 2 2 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 KOS15807.1 - 5.2e-05 23.5 0.1 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KOS15807.1 - 0.0045 17.2 0.2 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.16 KOS15807.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KOS15807.1 - 0.0058 16.7 0.0 0.069 13.2 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KOS15807.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KOS15807.1 - 0.0075 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_18 PF12847.2 KOS15807.1 - 0.013 16.1 0.0 0.11 13.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain IlvN PF07991.7 KOS15807.1 - 0.03 13.6 0.2 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3Beta_HSD PF01073.14 KOS15807.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_23 PF13489.1 KOS15807.1 - 0.14 11.8 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KOS15807.1 - 0.16 12.4 0.1 6.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain SIR2 PF02146.12 KOS15808.1 - 3e-21 75.9 0.1 3.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 Sir2 family DUF364 PF04016.7 KOS15808.1 - 0.0023 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF364) DUF2325 PF10087.4 KOS15808.1 - 0.079 12.8 0.2 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Ank_2 PF12796.2 KOS15809.1 - 5.6e-53 177.2 4.8 1.3e-20 73.5 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KOS15809.1 - 1.2e-38 128.9 13.0 1.7e-10 40.1 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KOS15809.1 - 1.3e-30 102.4 1.2 3.2e-07 29.9 0.1 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KOS15809.1 - 4e-27 93.6 9.9 1.2e-07 31.6 0.4 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS15809.1 - 4.5e-25 87.5 4.6 5.3e-11 42.7 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DUF1242 PF06842.7 KOS15809.1 - 2.9e-16 58.6 2.1 5.2e-16 57.8 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Cpn10 PF00166.16 KOS15810.1 - 4.6e-26 90.5 0.0 5.2e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Septin PF00735.13 KOS15811.1 - 9.4e-113 375.8 0.1 1.2e-112 375.5 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KOS15811.1 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KOS15811.1 - 1.1e-06 27.8 0.1 2.8e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KOS15811.1 - 1.4e-06 27.8 0.0 1.8e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KOS15811.1 - 9.8e-05 22.2 3.4 0.13 12.0 0.1 2.8 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 KOS15811.1 - 0.00026 21.1 0.3 0.0014 18.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 KOS15811.1 - 0.00026 20.2 0.0 0.00073 18.7 0.0 1.8 2 0 0 2 2 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KOS15811.1 - 0.00048 20.6 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KOS15811.1 - 0.0005 20.1 0.1 0.0058 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.4 KOS15811.1 - 0.00088 18.7 0.4 0.051 13.0 0.1 2.7 2 1 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 KOS15811.1 - 0.0015 17.9 0.0 0.0052 16.1 0.0 1.9 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.22 KOS15811.1 - 0.0016 18.7 0.0 0.0047 17.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 KOS15811.1 - 0.0026 16.9 0.0 0.0063 15.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MobB PF03205.9 KOS15811.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KOS15811.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KOS15811.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 KOS15811.1 - 0.0082 15.6 1.4 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KOS15811.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_10 PF12846.2 KOS15811.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KOS15811.1 - 0.018 14.8 0.0 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KOS15811.1 - 0.021 14.2 0.2 0.065 12.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 KOS15811.1 - 0.029 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.8 KOS15811.1 - 0.029 13.1 0.0 0.077 11.8 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.7 KOS15811.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KOS15811.1 - 0.036 13.9 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KOS15811.1 - 0.036 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 KOS15811.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KOS15811.1 - 0.055 13.6 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase FeoB_N PF02421.13 KOS15811.1 - 0.067 12.4 0.1 0.33 10.2 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KOS15811.1 - 0.1 12.0 0.4 8.3 5.8 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KOS15811.1 - 0.13 12.6 1.9 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KOS15812.1 - 2.5e-69 229.0 2.2 9.6e-24 82.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIID-18kDa PF02269.11 KOS15813.1 - 2.5e-31 107.3 1.4 6.6e-28 96.3 0.4 2.5 2 1 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit tRNA-synt_1b PF00579.20 KOS15813.1 - 0.072 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) RNase_P_Rpp14 PF01900.14 KOS15813.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Rpp14/Pop5 family NIF PF03031.13 KOS15814.1 - 1.8e-51 173.9 0.1 4e-51 172.8 0.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EIF_2_alpha PF07541.7 KOS15815.1 - 3.3e-44 149.2 0.6 6.1e-44 148.3 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KOS15815.1 - 1.4e-12 47.5 0.2 3.5e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DUF4312 PF14189.1 KOS15815.1 - 0.0013 18.4 0.8 0.11 12.3 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4312) EXOSC1 PF10447.4 KOS15815.1 - 0.053 13.4 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF2944 PF11161.3 KOS15815.1 - 0.076 12.6 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF4453 PF14627.1 KOS15815.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Ufd2P_core PF10408.4 KOS15816.1 - 1e-175 585.5 0.0 1.3e-175 585.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KOS15816.1 - 7.4e-29 99.5 0.4 7.8e-28 96.2 0.1 2.9 2 0 0 2 2 2 1 U-box domain B12D PF06522.6 KOS15817.1 - 6e-19 67.5 0.1 7.3e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ImmE5 PF11480.3 KOS15817.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Colicin-E5 Imm protein ABC2_membrane PF01061.19 KOS15818.1 - 7.7e-32 110.1 20.3 1.3e-31 109.3 14.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KOS15818.1 - 4.9e-25 88.4 0.0 7.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS15818.1 - 1.1e-07 32.1 0.0 2.8e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS15818.1 - 5.9e-05 22.3 0.1 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS15818.1 - 0.00017 21.0 0.9 0.00059 19.3 0.3 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS15818.1 - 0.00032 20.8 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS15818.1 - 0.00037 20.5 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS15818.1 - 0.0021 18.8 0.0 0.0041 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KOS15818.1 - 0.004 16.2 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KOS15818.1 - 0.0059 16.0 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 KOS15818.1 - 0.02 13.9 11.9 0.03 13.3 8.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.1 KOS15818.1 - 0.073 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS15818.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KOS15818.1 - 0.093 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 KOS15818.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS15818.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KOS15818.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KOS15818.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KOS15818.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC2_membrane PF01061.19 KOS15819.1 - 6.2e-30 103.9 22.1 1.1e-29 103.0 15.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KOS15819.1 - 9.6e-26 90.7 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KOS15819.1 - 2e-07 31.2 0.0 9.4e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KOS15819.1 - 2.5e-05 23.5 0.1 4.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KOS15819.1 - 0.00013 21.4 0.4 0.00047 19.6 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KOS15819.1 - 0.00015 21.9 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KOS15819.1 - 0.00023 20.3 0.0 0.39 9.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 KOS15819.1 - 0.00054 19.9 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KOS15819.1 - 0.0017 19.1 0.0 0.0039 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KOS15819.1 - 0.0063 15.9 0.5 0.24 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain UPF0182 PF03699.8 KOS15819.1 - 0.046 11.6 2.4 0.069 11.0 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Zeta_toxin PF06414.7 KOS15819.1 - 0.05 12.6 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 KOS15819.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KOS15819.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS15819.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS15819.1 - 0.091 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KOS15819.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KOS15819.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KOS15819.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KOS15819.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 KOS15819.1 - 0.17 11.3 0.2 0.22 11.0 0.1 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KOS15819.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.14 KOS15819.1 - 0.2 10.8 0.0 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Pro_isomerase PF00160.16 KOS15820.1 - 1.7e-47 161.5 0.0 3.5e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KOS15820.1 - 5.7e-13 48.1 0.2 0.0031 17.3 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat FadA PF09403.5 KOS15820.1 - 0.28 11.2 1.3 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Adhesion protein FadA 4HBT PF03061.17 KOS15821.1 - 5.9e-12 45.5 0.1 8.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Cpn60_TCP1 PF00118.19 KOS15822.1 - 2.1e-143 478.4 1.1 2.7e-143 478.1 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 KOS15822.1 - 0.017 14.9 0.4 0.099 12.5 0.1 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain PRK PF00485.13 KOS15823.1 - 1.8e-06 27.6 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.1 KOS15823.1 - 0.00038 19.9 0.0 0.00074 18.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KOS15823.1 - 0.0011 19.7 0.0 0.002 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS15823.1 - 0.0012 17.9 0.0 0.0026 16.8 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KOS15823.1 - 0.0026 17.7 0.0 0.0033 17.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 KOS15823.1 - 0.0026 16.5 0.0 0.0036 16.1 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 KOS15823.1 - 0.0042 16.9 0.1 0.0086 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS15823.1 - 0.008 15.9 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KOS15823.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KOS15823.1 - 0.012 15.9 0.4 0.025 14.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KOS15823.1 - 0.014 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 KOS15823.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KOS15823.1 - 0.047 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 KOS15823.1 - 0.061 12.8 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 KOS15823.1 - 0.066 11.8 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain cobW PF02492.14 KOS15823.1 - 0.068 12.6 0.3 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KOS15823.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 KOS15823.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KOS15823.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KOS15823.1 - 0.17 10.8 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Ribosomal_L18ae PF01775.12 KOS15824.1 - 1e-57 193.3 1.4 1.3e-57 193.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain THF_DHG_CYH PF00763.18 KOS15825.1 - 6.3e-19 68.1 0.0 2.5e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KOS15825.1 - 4.2e-15 55.1 0.0 9e-09 34.5 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KOS15825.1 - 0.01 15.9 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SBP_bac_5 PF00496.17 KOS15825.1 - 0.025 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TAF PF02969.12 KOS15826.1 - 6.5e-28 96.4 0.9 1.1e-27 95.7 0.3 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 KOS15826.1 - 6.2e-13 48.6 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 KOS15826.1 - 7e-05 22.8 0.3 0.00019 21.4 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KOS15826.1 - 0.046 13.4 0.3 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Bromodomain associated TFIID-31kDa PF02291.10 KOS15826.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SNARE PF05739.14 KOS15827.1 - 4.4e-18 64.7 2.5 4.4e-18 64.7 1.7 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 KOS15827.1 - 1.9e-17 63.1 3.5 1.6e-16 60.1 0.7 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.20 KOS15827.1 - 0.00069 19.7 0.7 0.00069 19.7 0.5 2.6 2 1 1 3 3 3 1 Syntaxin MCPsignal PF00015.16 KOS15827.1 - 0.016 14.7 3.1 0.21 11.1 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 KOS15827.1 - 0.052 13.1 1.4 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 Synaptobrevin Flu_M1_C PF08289.6 KOS15827.1 - 0.1 12.6 3.4 7.4 6.6 0.1 3.4 2 2 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Spc24 PF08286.6 KOS15827.1 - 0.28 10.8 5.5 5.9 6.6 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.8 KOS15827.1 - 0.33 10.7 5.4 0.29 10.8 1.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 KOS15827.1 - 0.48 10.2 3.1 2.7 7.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 KOS15827.1 - 0.51 10.7 3.0 5.9 7.3 0.1 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 KOS15827.1 - 1.8 6.8 7.6 19 3.5 5.1 2.0 1 1 0 1 1 1 0 AAA domain V-SNARE PF05008.10 KOS15827.1 - 3.5 7.8 10.7 0.25 11.5 1.1 3.2 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus DUF883 PF05957.8 KOS15827.1 - 4.6 7.7 6.8 0.76 10.2 0.6 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Adaptin_N PF01602.15 KOS15828.1 - 4.6e-147 490.5 7.4 5.4e-147 490.2 5.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KOS15828.1 - 3.2e-26 92.2 4.8 3.5e-22 79.0 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KOS15828.1 - 4.2e-15 55.7 15.2 7e-05 23.0 0.0 7.0 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.17 KOS15828.1 - 7.8e-09 34.8 5.3 0.084 13.0 0.0 6.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 KOS15828.1 - 2e-06 28.1 5.3 0.13 12.8 0.0 6.0 5 0 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.2 KOS15828.1 - 2.7e-05 23.3 0.7 0.0014 17.6 0.2 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 KOS15828.1 - 0.0025 17.2 0.9 0.26 10.6 0.1 3.0 3 2 0 3 3 3 1 CLASP N terminal Arm_2 PF04826.8 KOS15828.1 - 0.02 13.9 0.0 0.053 12.6 0.0 1.7 1 0 0 1 1 1 0 Armadillo-like eIF2_C PF09173.6 KOS15829.1 - 6.7e-38 128.6 0.1 1.6e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 KOS15829.1 - 5.4e-37 127.0 0.0 9.3e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KOS15829.1 - 8.3e-13 48.2 0.6 2.9e-12 46.5 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS15829.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS15829.1 - 0.046 13.5 0.2 0.15 11.8 0.1 2.2 1 1 0 1 1 1 0 Dynamin family Sod_Fe_C PF02777.13 KOS15830.1 - 1.8e-34 117.7 0.1 3.1e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KOS15830.1 - 2.5e-32 110.9 3.5 5.3e-32 109.9 2.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RrnaAD PF00398.15 KOS15831.1 - 1.4e-56 191.4 0.0 1.9e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KOS15831.1 - 2.4e-10 40.4 0.0 5e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS15831.1 - 7.4e-07 29.7 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS15831.1 - 3.5e-06 26.4 0.0 7.2e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KOS15831.1 - 5.3e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KOS15831.1 - 8.8e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KOS15831.1 - 0.0001 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS15831.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KOS15831.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KOS15831.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 KOS15831.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KOS15831.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 KOS15831.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Spermine_synth PF01564.12 KOS15831.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase DREV PF05219.7 KOS15831.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 KOS15831.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase E1-E2_ATPase PF00122.15 KOS15832.1 - 2.2e-21 75.9 0.0 2.2e-21 75.9 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KOS15832.1 - 7e-15 56.0 0.0 3e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS15832.1 - 7e-12 45.8 0.2 1.5e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS15832.1 - 8.2e-08 32.1 0.0 2.2e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KOS15832.1 - 0.00069 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mg_trans_NIPA PF05653.9 KOS15833.1 - 4.2e-50 170.4 6.4 5.4e-50 170.0 4.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KOS15833.1 - 1.9e-05 24.7 18.3 7.4e-05 22.7 1.1 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KOS15833.1 - 0.005 17.0 0.5 0.005 17.0 0.4 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Ctr PF04145.10 KOS15834.1 - 1.7e-36 125.4 0.5 2.4e-36 124.9 0.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KOS15834.1 - 0.045 13.2 0.3 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PIG-L PF02585.12 KOS15835.1 - 6e-27 94.6 0.2 8.5e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Peptidase_S9 PF00326.16 KOS15837.1 - 4.4e-16 58.7 0.0 5.4e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KOS15837.1 - 2.2e-06 27.1 0.0 2.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS15837.1 - 3.7e-06 26.7 0.0 1e-05 25.3 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS15837.1 - 1.1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KOS15837.1 - 4.9e-05 23.3 0.0 6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KOS15837.1 - 0.0011 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KOS15837.1 - 0.0047 16.5 0.0 0.0047 16.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS15837.1 - 0.015 14.7 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KOS15837.1 - 0.03 14.0 0.2 0.039 13.6 0.0 1.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KOS15837.1 - 0.087 12.3 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.9 KOS15837.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase SNF2_N PF00176.18 KOS15838.1 - 5.6e-37 127.1 0.0 8.4e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KOS15838.1 - 1.5e-07 31.1 13.9 3.1e-07 30.0 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS15838.1 - 2.7e-06 26.9 11.3 4.9e-06 26.1 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15838.1 - 9e-06 25.6 12.9 1.7e-05 24.7 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15838.1 - 1.2e-05 24.8 12.2 2.2e-05 24.0 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KOS15838.1 - 0.00011 22.0 0.0 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 KOS15838.1 - 0.00013 21.4 8.6 0.00028 20.3 5.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KOS15838.1 - 0.00069 19.2 13.4 0.0012 18.5 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C_4 PF13871.1 KOS15838.1 - 0.0026 17.2 1.2 0.037 13.4 0.1 2.4 2 0 0 2 2 2 1 Helicase_C-like zf-UDP PF14569.1 KOS15838.1 - 0.016 14.9 3.9 0.035 13.8 2.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Syntaxin-6_N PF09177.6 KOS15838.1 - 0.034 14.5 0.1 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 Syntaxin 6, N-terminal zf-RING_4 PF14570.1 KOS15838.1 - 0.049 13.2 9.9 0.098 12.2 6.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KOS15838.1 - 0.33 10.6 6.2 0.69 9.6 4.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KOS15838.1 - 0.63 9.9 9.9 1.1 9.1 6.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Caudo_TAP PF02413.12 KOS15838.1 - 1.1 9.3 5.9 1.7 8.7 0.2 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein zf-RING_6 PF14835.1 KOS15838.1 - 1.3 8.8 6.3 2.9 7.7 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mid1 PF12929.2 KOS15839.1 - 1.3e-75 254.8 1.8 5.4e-75 252.7 1.2 1.8 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KOS15839.1 - 0.0018 18.6 3.0 0.084 13.2 0.1 2.4 2 0 0 2 2 2 2 Fz domain FtsJ PF01728.14 KOS15839.1 - 0.053 13.4 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase VHS PF00790.14 KOS15840.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 VHS domain Oxidored-like PF09791.4 KOS15841.1 - 1.5e-05 24.3 0.1 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF1244 PF06844.6 KOS15841.1 - 0.044 13.5 0.1 0.072 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1244) MCM PF00493.18 KOS15842.1 - 3e-135 450.3 0.7 3e-135 450.3 0.5 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KOS15842.1 - 7.3e-21 74.8 0.0 2.7e-20 73.0 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS15842.1 - 8.6e-08 31.5 0.0 9.6e-07 28.1 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KOS15842.1 - 0.0013 18.2 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KOS15842.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS15842.1 - 0.025 14.3 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.9 KOS15842.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain Mito_carr PF00153.22 KOS15843.1 - 1e-69 230.2 1.6 5e-23 80.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KOS15844.1 - 2.4e-65 214.2 19.2 4.2e-13 48.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KOS15844.1 - 5.3e-05 21.5 6.3 0.24 9.4 0.2 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KOS15844.1 - 0.0073 14.6 0.0 1.1 7.5 0.1 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 KOS15844.1 - 0.036 13.7 0.7 40 4.0 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 KOS15844.1 - 0.093 11.4 1.3 2.1 7.0 0.1 2.8 2 1 1 3 3 3 0 Nup133 N terminal like PLU-1 PF08429.6 KOS15845.1 - 3.1e-50 170.9 0.4 5.1e-50 170.2 0.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 KOS15845.1 - 3.3e-42 143.3 0.2 8.3e-42 142.0 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 KOS15845.1 - 1.2e-14 53.4 0.0 2.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 KOS15845.1 - 1.2e-13 50.4 19.7 9.8e-09 34.7 3.7 2.7 2 0 0 2 2 2 2 PHD-finger zf-C5HC2 PF02928.11 KOS15845.1 - 1.5e-07 31.3 1.5 1.5e-07 31.3 1.1 3.0 4 0 0 4 4 2 1 C5HC2 zinc finger ARID PF01388.16 KOS15845.1 - 5.1e-06 26.2 0.0 1.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD_2 PF13831.1 KOS15845.1 - 0.049 12.9 10.7 0.7 9.2 1.8 3.0 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 KOS15845.1 - 0.086 12.1 6.9 0.11 11.7 0.3 2.7 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain ADK_lid PF05191.9 KOS15845.1 - 0.18 11.5 7.1 1.4 8.6 0.4 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_2 PF13639.1 KOS15845.1 - 0.86 9.4 22.0 2.2 8.1 5.2 2.9 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.1 KOS15845.1 - 0.87 9.3 26.0 0.11 12.3 5.0 3.1 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KOS15845.1 - 1.5 8.6 19.3 0.32 10.7 1.1 3.8 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KOS15845.1 - 7.9 6.5 16.0 11 6.1 1.4 3.0 2 0 0 2 2 2 0 RING-like domain Band_7 PF01145.20 KOS15846.1 - 1.5e-19 70.5 0.1 2.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family RA PF00788.18 KOS15847.1 - 5.2e-15 55.7 0.0 1e-11 45.1 0.0 3.4 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 KOS15847.1 - 3.1e-06 26.4 0.0 7.2e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS15847.1 - 0.00049 19.6 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_19 PF13245.1 KOS15847.1 - 0.0045 16.7 0.2 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain TUG-UBL1 PF11470.3 KOS15847.1 - 0.081 12.8 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Ras_bdg_2 PF14847.1 KOS15847.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Tim17 PF02466.14 KOS15848.1 - 7.8e-29 100.3 8.8 1.4e-27 96.3 6.1 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DHHW PF14286.1 KOS15848.1 - 0.1 11.9 0.3 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 DHHW protein RPA_C PF08784.6 KOS15849.1 - 1e-12 48.3 0.0 1.8e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KOS15849.1 - 3.5e-09 36.3 0.3 6.6e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ten1_2 PF15490.1 KOS15849.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.7 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit Sec23_trunk PF04811.10 KOS15850.1 - 1.5e-53 181.6 0.0 3.7e-53 180.3 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KOS15850.1 - 9.2e-25 86.0 0.1 1.6e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KOS15850.1 - 7.5e-18 64.8 0.0 1.8e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KOS15850.1 - 3e-16 58.6 4.6 6e-16 57.7 3.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KOS15850.1 - 0.00054 19.6 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Epimerase PF01370.16 KOS15851.1 - 3.6e-46 157.4 0.0 4.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KOS15851.1 - 3.6e-28 97.2 0.0 6.6e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KOS15851.1 - 2.8e-13 49.2 0.0 1.1e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KOS15851.1 - 5.1e-12 45.2 0.0 2.4e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KOS15851.1 - 1.9e-10 40.0 0.0 2.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KOS15851.1 - 6.4e-09 35.1 0.0 7.6e-08 31.5 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KOS15851.1 - 1.7e-06 28.0 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KOS15851.1 - 3.4e-05 23.5 0.1 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KOS15851.1 - 0.00025 21.0 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KOS15851.1 - 0.019 14.1 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family ATP_synt_H PF05493.8 KOS15852.1 - 1.1e-22 79.8 4.6 1.1e-22 79.7 3.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 KOS15852.1 - 0.06 12.7 0.7 0.066 12.6 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ARL6IP6 PF15062.1 KOS15852.1 - 0.12 12.3 0.6 0.16 11.8 0.2 1.4 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix Claudin_2 PF13903.1 KOS15852.1 - 0.14 11.8 1.4 0.15 11.7 1.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CoatB PF10389.4 KOS15852.1 - 0.41 10.5 3.3 0.68 9.8 2.3 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B WD40 PF00400.27 KOS15853.1 - 5.7e-13 48.2 9.9 0.00041 20.1 0.0 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS15853.1 - 3.8e-07 29.8 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 KOS15853.1 - 1.7e-06 28.0 3.7 0.32 11.3 0.0 4.7 5 0 0 5 5 5 2 PQQ-like domain PQQ PF01011.16 KOS15853.1 - 3.6e-06 26.2 0.2 0.12 11.9 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat YqzE PF14038.1 KOS15853.1 - 2.7 7.8 5.6 0.57 9.9 1.2 1.8 2 0 0 2 2 2 0 YqzE-like protein PDEase_II PF02112.10 KOS15854.1 - 5.1e-52 176.8 0.0 7.3e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KOS15854.1 - 4.5e-11 42.6 0.0 6.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS15854.1 - 0.025 14.2 3.3 0.16 11.6 2.3 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3349 PF11829.3 KOS15855.1 - 0.059 13.7 0.4 1.1 9.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) CTD_bind PF04818.8 KOS15855.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. FliX PF10768.4 KOS15855.1 - 1.8 8.8 7.1 0.14 12.3 1.2 2.0 2 0 0 2 2 2 0 Class II flagellar assembly regulator Las1 PF04031.8 KOS15856.1 - 4.7e-44 149.7 0.1 1.3e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 Las1-like Methyltransf_26 PF13659.1 KOS15857.1 - 3.4e-13 49.6 0.0 6.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KOS15857.1 - 9.9e-12 44.7 0.0 2.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 KOS15857.1 - 0.0015 18.0 0.0 0.21 11.0 0.0 2.5 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 KOS15857.1 - 0.12 11.4 0.0 1.4 7.9 0.0 1.9 2 0 0 2 2 2 0 N-6 DNA Methylase DUF974 PF06159.8 KOS15858.1 - 4.7e-25 88.4 0.0 1e-23 84.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF974) DUF4232 PF14016.1 KOS15858.1 - 0.005 16.4 3.0 0.046 13.3 0.3 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF4232) NPCBM_assoc PF10633.4 KOS15858.1 - 0.042 13.8 0.1 0.042 13.8 0.1 2.8 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase RabGAP-TBC PF00566.13 KOS15859.1 - 1.1e-22 80.6 1.2 3e-21 75.8 0.2 2.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain DUF2433 PF10360.4 KOS15860.1 - 1.6e-25 89.9 0.0 7.4e-25 87.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.17 KOS15860.1 - 0.007 15.9 0.0 0.1 12.2 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15860.1 - 0.014 15.3 0.1 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 KOS15860.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KOS15860.1 - 0.035 13.9 0.1 0.16 11.7 0.0 2.2 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Nup35_RRM PF05172.8 KOS15860.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF515 PF04415.7 KOS15860.1 - 2.8 6.0 10.4 4.4 5.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sporozoite_P67 PF05642.6 KOS15860.1 - 3.1 5.5 15.1 0.0047 14.8 1.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Thioredoxin PF00085.15 KOS15861.1 - 1.2e-31 108.4 0.1 7e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KOS15861.1 - 8.4e-09 35.4 0.0 2.9e-05 23.9 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KOS15861.1 - 4.1e-06 26.9 0.4 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KOS15861.1 - 9.2e-06 25.8 0.2 0.24 11.6 0.1 3.6 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS15861.1 - 1.2e-05 25.2 0.1 0.08 13.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.1 KOS15861.1 - 0.0034 17.1 0.1 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KOS15861.1 - 0.0087 16.0 0.4 0.59 10.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Med26 PF08711.6 KOS15862.1 - 0.024 14.1 0.1 0.057 12.9 0.1 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain NolV PF06635.7 KOS15862.1 - 0.05 12.7 0.8 0.094 11.8 0.5 1.4 1 0 0 1 1 1 0 Nodulation protein NolV STE3 PF02076.10 KOS15863.1 - 6.6e-36 123.8 9.1 1.9e-18 66.5 1.3 2.0 1 1 1 2 2 2 2 Pheromone A receptor RhoGEF PF00621.15 KOS15864.1 - 2.6e-40 138.2 1.6 5.1e-40 137.2 1.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KOS15864.1 - 2.8e-31 108.0 0.0 5.9e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KOS15864.1 - 5.5e-26 90.4 0.0 9.7e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KOS15864.1 - 8.3e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CENP-F_leu_zip PF10473.4 KOS15864.1 - 1.1 9.1 4.8 1.5 8.6 0.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3128 PF11326.3 KOS15865.1 - 4.1e-22 78.1 0.1 5.5e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Prefoldin PF02996.12 KOS15866.1 - 1.4e-31 108.5 0.0 1.8e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit HVSL PF09749.4 KOS15866.1 - 0.068 12.1 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Complex1_LYR PF05347.10 KOS15867.1 - 1.8e-07 30.8 0.1 3.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KOS15867.1 - 9.5e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 1 0 1 1 1 1 Complex1_LYR-like UQ_con PF00179.21 KOS15868.1 - 4.6e-35 120.0 0.0 5.1e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KOS15868.1 - 0.0026 17.5 0.1 0.01 15.6 0.1 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B RNase_PH PF01138.16 KOS15869.1 - 9.1e-23 81.0 0.0 2.1e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KOS15869.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Fimbrial_CS1 PF04449.7 KOS15869.1 - 0.042 13.9 0.2 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 CS1 type fimbrial major subunit RRM_1 PF00076.17 KOS15870.1 - 5.6e-78 256.5 0.0 2.3e-18 65.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15870.1 - 3.1e-70 232.0 0.3 5.2e-15 55.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15870.1 - 4.6e-38 128.8 0.0 6.8e-08 32.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 KOS15870.1 - 0.0004 20.3 0.0 0.17 11.9 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 KOS15870.1 - 0.00096 18.8 0.0 11 5.8 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KOS15870.1 - 0.067 12.9 0.0 8.5 6.2 0.0 3.7 3 0 0 3 3 3 0 Limkain b1 DUF221 PF02714.10 KOS15870.1 - 0.46 9.2 0.8 32 3.2 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF221 Gp_dh_C PF02800.15 KOS15871.1 - 1.4e-71 239.0 0.0 1.9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KOS15871.1 - 8.6e-61 204.3 0.1 1.3e-60 203.6 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KOS15871.1 - 0.096 12.6 0.1 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PEMT PF04191.8 KOS15872.1 - 3.3e-33 113.9 6.4 6.5e-33 113.0 4.4 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase YrhK PF14145.1 KOS15872.1 - 0.0088 15.6 10.2 2 8.1 4.9 2.8 2 1 0 2 2 2 1 YrhK-like protein TIM21 PF08294.6 KOS15873.1 - 2.1e-13 50.1 0.0 8.8e-09 35.1 0.0 2.6 2 1 0 2 2 2 2 TIM21 TatD_DNase PF01026.16 KOS15874.1 - 3.2e-47 160.9 0.1 4.4e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase bZIP_1 PF00170.16 KOS15875.1 - 6e-09 35.7 16.9 5e-07 29.5 6.0 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 KOS15875.1 - 2.3e-06 27.2 4.4 2.3e-06 27.2 3.0 2.0 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 MAD PF05557.8 KOS15875.1 - 0.0026 15.9 3.5 0.0035 15.5 2.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Tmemb_cc2 PF10267.4 KOS15875.1 - 0.008 14.8 1.3 0.013 14.1 0.9 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein bZIP_2 PF07716.10 KOS15875.1 - 0.15 11.8 18.0 3.9 7.3 2.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper ApbA_C PF08546.6 KOS15876.1 - 1.4e-37 128.5 0.0 2.3e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KOS15876.1 - 1.5e-21 76.3 0.0 9e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA COMPASS-Shg1 PF05205.7 KOS15877.1 - 2.2e-08 34.3 0.6 4.9e-08 33.2 0.3 1.6 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 OmpH PF03938.9 KOS15877.1 - 0.039 13.8 0.1 0.062 13.2 0.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2331 PF10093.4 KOS15877.1 - 0.092 11.5 2.8 0.11 11.2 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) PRKCSH_1 PF13015.1 KOS15879.1 - 0.00064 19.2 0.6 0.0014 18.1 0.1 1.8 1 1 1 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KOS15879.1 - 0.0075 17.0 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4051 PF13260.1 KOS15879.1 - 0.073 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) HpaP PF09483.5 KOS15880.1 - 0.024 14.6 9.2 0.031 14.2 6.4 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Pex14_N PF04695.8 KOS15880.1 - 0.062 13.3 5.8 0.11 12.5 4.0 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neuromodulin_N PF10580.4 KOS15880.1 - 0.13 11.8 0.2 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Gap junction protein N-terminal region DUF2360 PF10152.4 KOS15880.1 - 1.7 8.9 6.0 2.5 8.4 4.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Cnd1 PF12717.2 KOS15882.1 - 1.2e-56 191.3 4.0 9.3e-54 181.9 0.0 3.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 KOS15882.1 - 7.6e-41 139.5 0.0 1.1e-39 135.7 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 KOS15882.1 - 1.1e-06 28.1 5.2 0.099 12.7 0.1 6.7 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 KOS15882.1 - 1.5e-05 25.3 7.1 0.022 15.2 0.5 6.0 6 0 0 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 KOS15882.1 - 6.5e-05 21.4 1.1 0.0013 17.1 0.2 2.8 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 KOS15882.1 - 0.00063 19.9 11.4 0.032 14.5 0.2 5.6 7 1 1 8 8 8 2 HEAT repeats Cys_Met_Meta_PP PF01053.15 KOS15883.1 - 2e-153 510.2 0.0 2.2e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KOS15883.1 - 3.7e-14 52.4 0.0 5.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KOS15883.1 - 3.7e-12 45.9 0.0 1.4e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KOS15883.1 - 7.4e-12 44.6 0.1 3.4e-11 42.5 0.1 1.9 1 1 1 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KOS15883.1 - 5.3e-08 32.3 0.0 1.3e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KOS15883.1 - 0.00055 18.3 0.1 0.00088 17.6 0.1 1.4 1 1 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KOS15883.1 - 0.0082 14.6 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) CPSase_L_D2 PF02786.12 KOS15883.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GDC-P PF02347.11 KOS15883.1 - 0.027 13.1 0.1 0.042 12.5 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Radical_SAM PF04055.16 KOS15883.1 - 0.11 12.6 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily SOR_SNZ PF01680.12 KOS15884.1 - 1.3e-116 387.4 5.1 2.2e-116 386.7 3.6 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KOS15884.1 - 4.4e-07 29.2 4.9 4.5e-05 22.6 0.1 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KOS15884.1 - 0.0088 15.3 0.4 0.16 11.1 0.0 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 KOS15884.1 - 0.016 14.2 0.5 0.081 11.8 0.0 2.3 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 KOS15884.1 - 0.019 14.0 0.1 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Trp_syntA PF00290.15 KOS15884.1 - 0.046 12.2 0.0 0.086 11.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Dus PF01207.12 KOS15884.1 - 0.048 12.4 0.9 6.2 5.5 0.0 2.5 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.10 KOS15884.1 - 0.21 10.7 7.0 0.071 12.2 0.1 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase RNA_pol PF00940.14 KOS15885.1 - 2.5e-158 526.8 0.0 3.6e-158 526.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KOS15885.1 - 1.7e-77 260.8 3.0 2.9e-77 260.0 2.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 KOS15885.1 - 9.1e-05 22.3 0.0 0.079 12.9 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KOS15885.1 - 0.00028 20.9 0.3 0.19 12.0 0.0 3.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 KOS15885.1 - 0.072 13.0 1.7 3.7 7.7 0.0 3.5 3 0 0 3 3 3 0 PPR repeat PMT PF02366.13 KOS15886.1 - 1.4e-77 260.3 19.8 1.4e-77 260.3 13.7 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS15886.1 - 4.2e-17 62.3 0.2 7.6e-17 61.4 0.1 1.5 1 1 0 1 1 1 1 MIR domain Fascin PF06268.8 KOS15886.1 - 0.062 13.4 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Fascin domain Glyco_transf_22 PF03901.12 KOS15887.1 - 1.2e-70 238.5 22.7 1.5e-70 238.3 15.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3405 PF11885.3 KOS15888.1 - 1.6e-127 425.8 10.9 2.9e-71 240.2 3.5 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Glyco_transf_5 PF08323.6 KOS15888.1 - 0.085 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain NTF2 PF02136.15 KOS15889.1 - 2.9e-29 101.8 0.1 4.8e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KOS15889.1 - 2.2e-11 43.2 0.0 4.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15889.1 - 1.1e-08 34.8 0.0 3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15889.1 - 0.00013 21.6 0.1 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4055 PF13264.1 KOS15889.1 - 0.035 14.1 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) Daxx PF03344.10 KOS15889.1 - 8 4.8 6.0 11 4.3 4.2 1.1 1 0 0 1 1 1 0 Daxx Family Thioredoxin PF00085.15 KOS15890.1 - 8.9e-27 92.8 0.0 1.1e-25 89.3 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KOS15890.1 - 3.1e-07 30.5 0.1 3.1e-07 30.5 0.1 2.9 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KOS15890.1 - 0.00029 20.7 0.0 0.0013 18.7 0.0 2.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KOS15890.1 - 0.0024 17.9 0.0 0.015 15.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KOS15890.1 - 0.057 12.9 0.0 0.057 12.9 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin AhpC-TSA PF00578.16 KOS15890.1 - 0.09 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Ribosomal_S9 PF00380.14 KOS15892.1 - 1.4e-34 118.9 0.1 2.8e-34 117.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Vps35 PF03635.12 KOS15893.1 - 0 1013.6 0.0 0 1013.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Folliculin PF11704.3 KOS15893.1 - 0.043 13.3 1.0 11 5.5 0.1 3.2 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Vma12 PF11712.3 KOS15894.1 - 2.6e-16 59.5 0.0 3.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Mito_carr PF00153.22 KOS15895.1 - 3.1e-66 219.1 1.3 6e-23 80.3 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein CRF PF00473.12 KOS15895.1 - 0.047 13.7 1.4 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Corticotropin-releasing factor family Prefoldin_2 PF01920.15 KOS15896.1 - 1.2e-16 60.3 5.7 1.4e-16 60.1 4.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KOS15896.1 - 0.0034 17.0 4.0 0.0099 15.5 2.8 1.7 1 1 0 1 1 1 1 Prefoldin subunit PhoU_div PF01865.11 KOS15896.1 - 0.034 13.3 3.7 0.6 9.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF47 Prefoldin_3 PF13758.1 KOS15896.1 - 0.06 13.1 1.7 0.094 12.4 1.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit ADK PF00406.17 KOS15896.1 - 0.067 13.0 0.2 0.091 12.6 0.1 1.4 1 1 0 1 1 1 0 Adenylate kinase Ferritin PF00210.19 KOS15896.1 - 0.089 12.5 0.3 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Ferritin-like domain UBN2 PF14223.1 KOS15896.1 - 0.15 11.8 2.2 4.2 7.1 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type IncA PF04156.9 KOS15896.1 - 0.52 9.8 4.0 1 8.8 2.8 1.5 1 1 0 1 1 1 0 IncA protein dCMP_cyt_deam_1 PF00383.17 KOS15897.1 - 8.1e-24 83.2 0.0 1.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KOS15897.1 - 2.4e-05 24.2 0.1 4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KOS15897.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KOS15897.1 - 0.19 11.4 0.4 2.6 7.7 0.3 2.1 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase LSM PF01423.17 KOS15898.1 - 3.3e-18 65.0 0.2 4.5e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KOS15898.1 - 0.81 10.1 5.0 1.5 9.3 3.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PhoD PF09423.5 KOS15899.1 - 1.8e-06 26.8 0.0 0.04 12.4 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Aldedh PF00171.17 KOS15900.1 - 1e-103 347.1 0.0 1.2e-103 346.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ChaC PF04752.7 KOS15901.1 - 6.6e-50 169.5 0.0 1.4e-49 168.4 0.0 1.6 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 KOS15901.1 - 9e-25 86.2 1.7 2.3e-24 84.9 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KOS15901.1 - 6.3e-10 38.9 1.3 6.3e-10 38.9 0.9 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS15901.1 - 7.9e-09 35.4 4.9 3.4e-08 33.3 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KOS15901.1 - 4.9e-05 23.3 5.2 0.035 14.2 0.2 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KOS15901.1 - 0.0024 18.0 4.0 0.56 10.6 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KOS15901.1 - 0.0048 17.1 3.4 0.086 13.2 0.4 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KOS15901.1 - 0.02 14.7 2.9 1.3 8.9 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger GST_N PF02798.15 KOS15902.1 - 2.2e-08 34.1 0.0 5.6e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS15902.1 - 6.1e-08 32.5 0.1 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS15902.1 - 6.7e-06 26.2 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS15902.1 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS15902.1 - 0.0002 21.1 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS15902.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CHCH PF06747.8 KOS15903.1 - 0.00011 22.0 1.9 0.00011 22.0 1.3 2.3 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 KOS15903.1 - 0.37 10.6 8.6 1.2 8.9 2.0 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KOS15903.1 - 1 9.4 9.1 2.7 8.1 3.5 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Acetyltransf_1 PF00583.19 KOS15904.1 - 2e-14 53.3 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS15904.1 - 2.1e-06 27.3 0.1 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KOS15904.1 - 1.5e-05 25.0 0.0 1.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS15904.1 - 0.00026 21.0 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS15904.1 - 0.00041 20.3 0.0 0.00061 19.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KOS15904.1 - 0.005 17.0 0.0 0.0073 16.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS15904.1 - 0.0052 16.6 0.1 0.0097 15.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GST_N PF02798.15 KOS15905.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS15905.1 - 0.0059 16.5 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KOS15905.1 - 0.007 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cyt-b5 PF00173.23 KOS15906.1 - 5.9e-19 67.6 0.0 8e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MCM PF00493.18 KOS15907.1 - 4.7e-140 466.0 0.1 6.1e-140 465.7 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KOS15907.1 - 1.1e-17 64.6 0.0 2.2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KOS15907.1 - 1.2e-06 27.8 0.0 0.00037 19.7 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS15907.1 - 8.3e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KOS15907.1 - 0.00084 18.9 0.0 0.0049 16.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KOS15907.1 - 0.029 13.8 0.0 0.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF664 PF04978.7 KOS15907.1 - 0.052 13.7 0.3 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF664) MgsA_C PF12002.3 KOS15907.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal AAA PF00004.24 KOS15907.1 - 0.12 12.6 0.1 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pam17 PF08566.5 KOS15908.1 - 2e-53 180.6 0.0 2.2e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Thymidylat_synt PF00303.14 KOS15909.1 - 4.3e-107 357.1 0.0 5.5e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 KOS15909.1 - 2.6e-26 92.6 0.0 9.4e-26 90.7 0.0 2.0 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 KOS15910.1 - 6.6e-16 57.7 0.3 1.1e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15910.1 - 4.9e-12 45.6 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15910.1 - 4.1e-09 36.1 1.0 5.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS15910.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif AAA PF00004.24 KOS15911.1 - 1.5e-40 138.4 0.0 2.5e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS15911.1 - 5.1e-07 29.8 0.2 0.0022 18.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 KOS15911.1 - 2.5e-05 24.2 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KOS15911.1 - 6.5e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KOS15911.1 - 7.6e-05 22.4 0.8 0.00056 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS15911.1 - 0.0003 20.8 0.2 0.0029 17.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KOS15911.1 - 0.00049 20.0 0.6 0.051 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KOS15911.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KOS15911.1 - 0.0021 17.9 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KOS15911.1 - 0.0045 16.6 0.1 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KOS15911.1 - 0.0049 16.2 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KOS15911.1 - 0.0052 17.5 0.9 0.014 16.2 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS15911.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KOS15911.1 - 0.006 15.7 0.1 0.11 11.6 0.1 2.2 1 1 1 2 2 2 1 KaiC AAA_19 PF13245.1 KOS15911.1 - 0.0074 16.0 0.4 0.015 15.0 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KOS15911.1 - 0.011 16.0 0.2 0.031 14.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KOS15911.1 - 0.022 13.6 0.0 0.051 12.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 KOS15911.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KOS15911.1 - 0.038 12.7 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KOS15911.1 - 0.038 13.3 1.0 1.9 7.8 0.2 2.3 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 KOS15911.1 - 0.07 12.3 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 KOS15911.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KOS15911.1 - 0.08 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KOS15911.1 - 0.1 12.2 0.2 0.42 10.2 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KOS15911.1 - 0.1 11.7 0.1 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KOS15911.1 - 0.16 11.5 0.2 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KOS15912.1 - 2.8e-66 223.3 0.0 4.1e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS15912.1 - 3.8e-12 45.9 0.0 7.4e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KOS15912.1 - 4e-08 33.1 4.7 4e-08 33.1 3.3 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15912.1 - 2.3e-07 30.3 4.3 2.3e-07 30.3 3.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KOS15912.1 - 6.6e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS15912.1 - 7.7e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KOS15912.1 - 1.4e-06 27.9 7.2 1.4e-06 27.9 5.0 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KOS15912.1 - 1.9e-05 24.2 5.0 1.9e-05 24.2 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS15912.1 - 0.0026 17.4 5.1 0.0026 17.4 3.5 2.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KOS15912.1 - 0.012 15.2 0.4 0.036 13.7 0.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Tmpp129 PF10272.4 KOS15912.1 - 0.022 13.5 0.2 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor AAA_22 PF13401.1 KOS15912.1 - 0.053 13.6 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zn_Tnp_IS91 PF14319.1 KOS15912.1 - 1.3 8.5 10.8 0.057 12.9 0.5 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-C3HC4_4 PF15227.1 KOS15912.1 - 5.1 7.0 16.6 0.028 14.2 2.1 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DLH PF01738.13 KOS15913.1 - 7.7e-15 54.7 0.0 9.4e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KOS15913.1 - 2.7e-05 23.9 0.0 5.8e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family RICTOR_N PF14664.1 KOS15914.1 - 4.9e-56 189.9 4.7 2.3e-52 177.8 1.2 2.4 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KOS15914.1 - 1.3e-51 174.7 0.0 6e-48 162.8 0.0 3.3 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 KOS15914.1 - 7.6e-17 61.0 5.4 1.8e-15 56.5 1.3 3.8 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 KOS15914.1 - 4.3e-07 29.8 0.0 1.7e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HR1 PF02185.11 KOS15914.1 - 0.0029 17.3 1.2 0.0042 16.8 0.3 1.7 2 0 0 2 2 2 1 Hr1 repeat DUF3818 PF12825.2 KOS15915.1 - 2.6e-39 134.8 0.0 2.6e-39 134.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KOS15915.1 - 7.8e-15 54.6 0.1 2.6e-14 52.9 0.1 2.0 1 0 0 1 1 1 1 PX-associated Coa1 PF08695.5 KOS15916.1 - 5e-31 106.6 0.0 7.8e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Rhomboid PF01694.17 KOS15917.1 - 3.1e-07 30.5 1.7 3.3e-07 30.4 0.4 1.6 2 0 0 2 2 2 1 Rhomboid family ATP-synt_S1 PF05827.7 KOS15918.1 - 0.00054 19.3 3.5 0.16 11.2 0.5 2.2 1 1 0 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) MT-A70 PF05063.9 KOS15919.1 - 2.1e-13 50.2 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 MT-A70 zf-LYAR PF08790.6 KOS15920.1 - 1e-09 37.8 1.8 3.2e-09 36.3 1.3 1.9 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger AUX_IAA PF02309.11 KOS15920.1 - 0.065 12.9 7.5 0.082 12.6 5.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Caldesmon PF02029.10 KOS15920.1 - 0.89 7.9 15.9 1.7 6.9 11.0 1.4 1 1 0 1 1 1 0 Caldesmon Paramyxo_ncap PF00973.14 KOS15920.1 - 1.2 7.8 7.4 1.4 7.5 5.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.11 KOS15920.1 - 1.2 8.9 6.8 1.4 8.7 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP-synt_Eps PF04627.8 KOS15921.1 - 3.4e-18 64.9 2.6 3.9e-18 64.7 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DASH_Dad1 PF08649.5 KOS15922.1 - 1.8e-16 59.5 0.3 2.2e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Glyco_transf_4 PF13439.1 KOS15922.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PDT PF00800.13 KOS15923.1 - 5.9e-06 25.9 0.0 9.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase Thioredox_DsbH PF03190.10 KOS15923.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Mago-bind PF09282.5 KOS15924.1 - 1.2e-12 47.0 1.0 2.5e-12 46.1 0.7 1.5 1 0 0 1 1 1 1 Mago binding Med10 PF09748.4 KOS15925.1 - 4.2e-22 78.3 0.0 5.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Mis14 PF08641.7 KOS15925.1 - 0.03 14.3 0.4 0.046 13.7 0.3 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like FUSC PF04632.7 KOS15925.1 - 0.044 12.2 0.1 0.065 11.6 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family NIT PF08376.5 KOS15925.1 - 0.062 12.8 1.7 0.13 11.7 0.7 1.8 1 1 1 2 2 2 0 Nitrate and nitrite sensing RRM_1 PF00076.17 KOS15926.1 - 1.9e-14 53.0 0.0 1.8e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS15926.1 - 6.3e-09 35.6 0.0 0.00031 20.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS15926.1 - 8e-09 35.2 0.1 0.004 16.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 KOS15927.1 - 1.6e-08 34.5 0.0 5.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KOS15927.1 - 1.4e-07 31.4 0.0 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain HIG_1_N PF04588.8 KOS15928.1 - 3.1e-15 55.6 0.0 4.4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1510 PF07423.6 KOS15928.1 - 0.02 14.3 0.2 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TPR_11 PF13414.1 KOS15929.1 - 4.2e-39 132.0 23.6 6.7e-18 64.1 1.4 5.4 4 1 1 5 5 5 5 TPR repeat DnaJ PF00226.26 KOS15929.1 - 4.1e-24 84.0 3.0 6.7e-24 83.3 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 KOS15929.1 - 1.4e-23 80.7 27.1 0.00026 20.6 0.0 8.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 KOS15929.1 - 1.5e-23 81.3 21.0 1.5e-07 30.7 0.0 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KOS15929.1 - 2.6e-17 62.9 26.7 2.3e-05 24.9 0.4 6.3 4 3 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 KOS15929.1 - 3.6e-16 59.2 24.1 3.3e-05 24.1 0.9 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KOS15929.1 - 5.9e-16 57.5 26.0 0.025 15.2 0.1 8.0 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15929.1 - 1.2e-13 50.7 20.6 2.8e-07 30.3 0.6 5.5 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KOS15929.1 - 1.5e-09 37.2 14.9 0.008 16.3 0.2 7.2 9 0 0 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KOS15929.1 - 1.7e-09 37.7 11.3 3.6e-07 30.2 0.2 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KOS15929.1 - 1.9e-09 36.6 14.8 0.18 11.6 0.1 7.5 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS15929.1 - 2.2e-06 27.0 21.0 0.067 13.0 0.2 7.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KOS15929.1 - 3.9e-06 26.6 22.0 0.068 13.0 0.1 6.4 3 3 4 7 7 7 4 Tetratricopeptide repeat DUF3856 PF12968.2 KOS15929.1 - 0.00045 20.0 9.9 0.95 9.2 2.1 4.4 2 2 1 3 3 3 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 KOS15929.1 - 0.0016 17.6 3.8 0.26 10.5 0.2 4.1 4 0 0 4 4 4 1 SHNi-TPR TPR_6 PF13174.1 KOS15929.1 - 0.16 12.4 29.3 0.19 12.2 0.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 KOS15929.1 - 0.46 10.6 26.2 0.49 10.5 1.2 5.9 3 2 3 6 6 6 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.2 KOS15930.1 - 0.0046 16.8 8.0 0.0046 16.8 5.5 3.7 1 1 2 3 3 3 2 Tropomyosin like muHD PF10291.4 KOS15931.1 - 8.5e-21 74.2 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KOS15931.1 - 6.2e-10 39.1 0.0 6.2e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Plus-3 PF03126.13 KOS15932.1 - 1.5e-16 60.3 0.0 5.2e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain Casc1 PF12366.3 KOS15932.1 - 1.3 8.4 7.0 0.63 9.4 2.8 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 SR-25 PF10500.4 KOS15933.1 - 0.084 12.3 10.1 0.21 11.0 7.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VTC PF09359.5 KOS15934.1 - 4e-103 344.3 0.0 7.6e-103 343.4 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KOS15934.1 - 3.5e-32 112.2 9.8 3.5e-32 112.2 6.8 3.5 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 KOS15934.1 - 8.6e-12 45.1 3.9 2e-11 43.9 2.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 KOS15934.1 - 1 9.0 4.4 8.8 6.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Ribosomal_S4 PF00163.14 KOS15935.1 - 1.8e-12 47.4 1.9 3e-12 46.7 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KOS15935.1 - 3.9e-12 45.4 0.0 1e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 S4 domain Glyco_transf_15 PF01793.11 KOS15936.1 - 3.9e-139 463.2 5.9 4.8e-139 462.9 4.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIT PF15330.1 KOS15936.1 - 0.03 14.4 0.1 0.078 13.1 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TIP49 PF06068.8 KOS15937.1 - 2.1e-179 596.3 0.1 2.6e-179 596.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KOS15937.1 - 4.4e-10 39.0 0.5 5e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KOS15937.1 - 9.3e-10 38.8 1.5 2.3e-05 24.5 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS15937.1 - 1.1e-05 25.6 0.4 0.086 12.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KOS15937.1 - 8.8e-05 22.1 0.2 0.00069 19.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KOS15937.1 - 0.00018 21.2 0.1 0.083 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KOS15937.1 - 0.00023 21.1 0.3 0.045 13.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KOS15937.1 - 0.00039 19.8 0.3 0.00095 18.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KOS15937.1 - 0.0021 18.0 0.1 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS15937.1 - 0.0036 16.7 0.2 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KOS15937.1 - 0.013 14.9 0.1 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KOS15937.1 - 0.014 14.5 0.1 0.98 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 KOS15937.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 KOS15937.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KOS15937.1 - 0.042 12.9 0.2 0.091 11.8 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 KOS15937.1 - 0.049 13.2 0.1 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KOS15937.1 - 0.14 11.8 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain URO-D PF01208.12 KOS15938.1 - 5.1e-130 433.3 0.0 5.9e-130 433.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) BING4CT PF08149.6 KOS15938.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain PMT PF02366.13 KOS15939.1 - 4.8e-72 242.2 17.6 4.8e-72 242.2 12.2 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KOS15939.1 - 6.2e-36 123.7 2.5 3e-35 121.4 1.0 2.4 2 1 0 2 2 2 1 MIR domain EMG1 PF03587.9 KOS15940.1 - 1.2e-75 253.2 0.2 9.7e-75 250.2 0.0 1.9 2 0 0 2 2 2 1 EMG1/NEP1 methyltransferase Phostensin_N PF13916.1 KOS15940.1 - 0.01 15.7 1.5 0.025 14.5 1.0 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal TFIIA PF03153.8 KOS15940.1 - 1.1 9.1 11.3 1.5 8.6 7.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APC_CDC26 PF10471.4 KOS15940.1 - 1.2 9.9 8.6 0.26 12.0 3.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Suf PF05843.9 KOS15940.1 - 3 7.5 6.0 4.5 6.9 4.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SNARE PF05739.14 KOS15941.1 - 5.8e-19 67.5 1.5 5.8e-19 67.5 1.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KOS15941.1 - 9.3e-07 28.9 10.5 4.1e-06 26.9 2.6 2.8 2 1 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 KOS15941.1 - 0.0018 17.8 10.4 0.0029 17.1 1.7 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 KOS15941.1 - 0.0057 16.2 0.4 0.0057 16.2 0.3 2.3 2 1 1 3 3 3 1 Synaptobrevin DUF2562 PF10814.3 KOS15941.1 - 0.099 12.5 2.9 0.097 12.6 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Mt_ATP-synt_B PF05405.9 KOS15941.1 - 1.9 7.9 8.7 0.86 9.0 4.1 1.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kinesin PF00225.18 KOS15942.1 - 2.1e-83 279.8 0.0 3.1e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Haem_oxygenas_2 PF14518.1 KOS15942.1 - 0.12 12.5 0.1 2 8.6 0.1 2.4 1 1 0 1 1 1 0 Iron-containing redox enzyme Sec63 PF02889.11 KOS15943.1 - 5.1e-21 75.2 0.0 7.4e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KOS15943.1 - 1.5e-16 59.9 0.7 2.9e-16 58.9 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S11 PF00411.14 KOS15944.1 - 2.5e-14 53.3 0.2 3.6e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2423 PF10338.4 KOS15946.1 - 9.1e-13 47.9 4.5 2.2e-12 46.7 3.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Calreticulin PF00262.13 KOS15946.1 - 0.021 13.4 0.2 0.025 13.2 0.2 1.1 1 0 0 1 1 1 0 Calreticulin family DPM3 PF08285.6 KOS15947.1 - 2.3e-26 91.4 0.1 2.5e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF165 PF02592.10 KOS15947.1 - 0.061 13.5 0.7 0.081 13.1 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 TIP41 PF04176.8 KOS15948.1 - 4.8e-42 143.2 0.0 1.7e-39 134.9 0.0 2.2 2 0 0 2 2 2 2 TIP41-like family DUF1655 PF07868.6 KOS15948.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) TatD_DNase PF01026.16 KOS15949.1 - 5.8e-34 117.4 0.0 7e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase SAE2 PF08573.5 KOS15951.1 - 0.00057 20.5 0.9 0.00057 20.5 0.7 3.3 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus CENP-Q PF13094.1 KOS15951.1 - 0.0057 16.7 0.7 0.0088 16.0 0.5 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3987 PF13148.1 KOS15951.1 - 0.01 14.4 1.3 0.014 14.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) PilJ PF13675.1 KOS15951.1 - 0.014 15.7 1.2 0.03 14.6 0.8 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ank_2 PF12796.2 KOS15952.1 - 4.3e-23 81.4 3.1 3.7e-12 46.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KOS15952.1 - 1.3e-14 53.1 0.3 8e-08 31.7 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat TIG PF01833.19 KOS15952.1 - 4.7e-13 48.9 2.9 1.4e-12 47.3 1.3 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.1 KOS15952.1 - 1.2e-12 47.9 0.2 4.8e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS15952.1 - 1.1e-10 41.4 3.2 1.2e-08 34.9 0.8 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS15952.1 - 4.4e-10 38.8 0.1 4.3e-05 23.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat CDC45 PF02724.9 KOS15952.1 - 1.2 7.1 6.2 2.4 6.0 4.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KOS15952.1 - 1.3 7.4 15.9 0.18 10.2 6.1 2.3 2 0 0 2 2 2 0 Daxx Family CENP-B_dimeris PF09026.5 KOS15952.1 - 2 8.6 13.5 6.1 7.1 9.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.27 KOS15954.1 - 1.2e-16 59.8 10.1 6e-06 25.9 0.1 4.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Pmp3 PF01679.12 KOS15955.1 - 1e-14 53.9 7.1 1.6e-14 53.3 5.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Cation_efflux PF01545.16 KOS15956.1 - 9.7e-45 152.8 14.1 5.3e-30 104.4 2.5 3.2 2 1 1 3 3 3 3 Cation efflux family DUF1230 PF06799.6 KOS15956.1 - 8.7 6.2 6.7 2.7 7.8 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1230) Mur_ligase_M PF08245.7 KOS15959.1 - 2.2e-06 27.8 0.0 1e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain PrpF PF04303.8 KOS15960.1 - 1.3e-51 175.5 5.7 1.9e-34 119.0 2.7 3.0 2 1 0 2 2 2 2 PrpF protein Peripla_BP_2 PF01497.13 KOS15960.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein FIST PF08495.5 KOS15961.1 - 0.0035 16.5 0.0 0.37 9.9 0.0 2.5 2 0 0 2 2 2 2 FIST N domain PBP PF01161.15 KOS15962.1 - 1.5e-20 73.5 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DnaJ PF00226.26 KOS15963.1 - 6.5e-18 64.2 0.3 1.2e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KOS15963.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein SpoVR PF04293.8 KOS15963.1 - 0.84 7.9 5.6 1.2 7.4 3.9 1.1 1 0 0 1 1 1 0 SpoVR like protein Asp PF00026.18 KOS15964.1 - 1e-44 153.1 0.9 2.2e-44 152.0 0.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KOS15964.1 - 8.3e-12 45.4 0.1 8.6e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KOS15964.1 - 0.00042 19.8 0.2 0.002 17.6 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KOS15964.1 - 0.072 12.9 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 KOS15964.1 - 0.093 12.6 0.2 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2454 PF10521.4 KOS15965.1 - 5.6e-12 45.2 0.0 2.2e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) Sec34 PF04136.10 KOS15966.1 - 1.8e-16 60.2 0.7 4.4e-16 58.9 0.4 1.7 2 0 0 2 2 2 1 Sec34-like family Phg_2220_C PF09524.5 KOS15966.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) DUF2347 PF09804.4 KOS15967.1 - 2.1e-37 128.9 0.0 2.6e-35 122.0 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 KOS15967.1 - 0.093 11.1 0.2 7.1 4.9 0.0 2.6 2 1 1 3 3 3 0 Transport protein Avl9 zf-C3HC4_3 PF13920.1 KOS15968.1 - 1.7e-05 24.4 8.1 1.7e-05 24.4 5.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 KOS15968.1 - 0.81 10.1 31.3 0.12 12.7 2.1 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type LAG1-DNAbind PF09271.6 KOS15969.1 - 1e-23 84.3 0.0 5.6e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KOS15969.1 - 1.3e-20 73.7 0.0 3.6e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain DUF501 PF04417.7 KOS15969.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) HEAT_2 PF13646.1 KOS15971.1 - 1e-06 28.9 1.1 0.011 16.0 0.0 4.8 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.17 KOS15971.1 - 1.1e-05 25.1 4.8 0.63 10.2 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.15 KOS15971.1 - 0.048 11.9 0.0 0.12 10.6 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region DNA_ligase_A_M PF01068.16 KOS15972.1 - 2.4e-09 36.8 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 KOS15972.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain SelB-wing_2 PF09106.6 KOS15972.1 - 0.029 14.2 0.2 0.91 9.5 0.0 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Actin PF00022.14 KOS15973.1 - 4.8e-29 100.9 0.0 1.5e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS15973.1 - 0.023 13.2 0.0 0.42 9.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Tex_N PF09371.5 KOS15973.1 - 0.19 11.0 0.2 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Actin PF00022.14 KOS15974.1 - 8.1e-118 393.2 0.0 9.2e-118 393.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KOS15974.1 - 0.003 16.2 0.0 0.018 13.6 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Pkinase PF00069.20 KOS15975.1 - 8.6e-72 241.4 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15975.1 - 7.7e-32 110.3 0.0 9.7e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS15975.1 - 0.00015 20.9 0.0 0.00047 19.2 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS15975.1 - 0.00079 19.2 0.1 0.0021 17.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS15975.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KOS15975.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KOS15976.1 - 4.6e-38 130.8 0.0 3.7e-37 127.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15976.1 - 5.8e-20 71.4 0.0 7.2e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS15976.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS15976.1 - 0.0032 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KOS15976.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gemini_AL2 PF01440.11 KOS15976.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL2 protein Apc4_WD40 PF12894.2 KOS15976.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Choline_kinase PF01633.15 KOS15976.1 - 0.19 11.3 0.0 0.98 8.9 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase EF1G PF00647.14 KOS15977.1 - 6.4e-43 144.8 0.0 1.1e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 KOS15977.1 - 7.2e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KOS15977.1 - 5.1e-10 39.0 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KOS15977.1 - 5.1e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KOS15977.1 - 1.3e-09 37.9 0.1 6.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KOS15977.1 - 3.8e-07 30.4 0.0 1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KOS15977.1 - 3.9e-06 26.7 0.0 8.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Bap31 PF05529.7 KOS15978.1 - 2.5e-52 177.1 7.7 3.9e-52 176.5 5.4 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like IFT57 PF10498.4 KOS15978.1 - 0.0054 15.5 3.4 0.0063 15.2 2.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 RmuC PF02646.11 KOS15978.1 - 0.0067 15.2 0.6 0.0082 15.0 0.4 1.2 1 0 0 1 1 1 1 RmuC family UPF0118 PF01594.11 KOS15978.1 - 0.015 14.2 6.2 0.72 8.7 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 TRP PF06011.7 KOS15978.1 - 0.031 12.8 5.8 0.47 8.9 0.3 2.2 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel OmpH PF03938.9 KOS15978.1 - 0.32 10.9 7.4 0.053 13.4 2.2 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1077 PF06417.7 KOS15978.1 - 1.7 7.9 6.6 0.16 11.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1077) DivIC PF04977.10 KOS15978.1 - 2.6 7.5 6.7 1.4 8.4 2.4 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF4446 PF14584.1 KOS15978.1 - 3.6 7.4 7.6 0.29 10.9 0.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF2681 PF10883.3 KOS15978.1 - 5.6 7.2 9.4 2 8.7 2.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) ALO PF04030.9 KOS15979.1 - 1.1e-61 208.7 1.1 1.9e-61 207.8 0.8 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KOS15979.1 - 2.9e-18 65.6 0.0 6.9e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_dim PF02852.17 KOS15980.1 - 2.5e-41 140.1 0.1 5.6e-41 139.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KOS15980.1 - 4.6e-38 131.1 14.9 4.4e-37 127.9 10.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS15980.1 - 1.3e-22 79.9 11.1 4.8e-21 74.9 1.0 3.6 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KOS15980.1 - 1.2e-11 44.3 6.9 6.9e-10 38.5 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 KOS15980.1 - 6.8e-11 41.6 2.3 2.2e-09 36.6 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KOS15980.1 - 2.3e-09 37.6 0.5 3.7e-05 23.8 0.1 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS15980.1 - 2.4e-08 33.8 4.2 0.00032 20.6 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KOS15980.1 - 1.3e-07 31.0 5.6 0.0051 15.9 0.0 3.8 3 1 0 4 4 4 3 FAD binding domain HI0933_like PF03486.9 KOS15980.1 - 1.8e-07 30.0 11.3 0.0001 20.9 0.6 4.1 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 KOS15980.1 - 1e-06 27.8 1.9 1e-06 27.8 1.3 3.9 3 1 1 4 4 4 1 FAD binding domain Thi4 PF01946.12 KOS15980.1 - 2.1e-06 27.0 5.2 0.00031 19.8 0.1 2.5 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 KOS15980.1 - 2.2e-05 24.0 2.8 0.032 13.7 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KOS15980.1 - 3e-05 23.0 14.6 0.018 13.9 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KOS15980.1 - 4.2e-05 22.6 0.8 0.017 14.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KOS15980.1 - 0.013 14.5 0.7 0.094 11.7 0.2 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase F420_oxidored PF03807.12 KOS15980.1 - 0.14 12.5 4.1 0.99 9.8 0.1 3.2 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.7 KOS15980.1 - 0.37 9.6 7.1 0.75 8.6 0.4 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein DUF89 PF01937.14 KOS15981.1 - 8e-109 363.6 0.0 9.8e-109 363.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Thioredoxin PF00085.15 KOS15982.1 - 2.4e-55 184.6 0.3 2.2e-29 101.2 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KOS15982.1 - 2.9e-40 138.0 0.2 3.8e-33 114.8 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KOS15982.1 - 1.7e-12 47.2 0.1 0.02 15.0 0.0 4.7 4 1 0 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.1 KOS15982.1 - 1.8e-09 37.7 5.5 0.056 13.6 1.1 5.5 2 2 0 3 3 3 3 Thioredoxin-like domain AhpC-TSA PF00578.16 KOS15982.1 - 1e-07 31.6 1.1 0.3 10.7 0.0 4.2 4 0 0 4 4 4 3 AhpC/TSA family Thioredoxin_7 PF13899.1 KOS15982.1 - 2.5e-07 30.5 0.2 0.0085 16.0 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_4 PF13462.1 KOS15982.1 - 5.4e-06 26.5 0.2 0.0017 18.3 0.1 2.7 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.5 KOS15982.1 - 0.00027 20.4 0.6 1.2 8.6 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_9 PF14595.1 KOS15982.1 - 0.0059 16.1 0.2 1 8.9 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 KOS15982.1 - 0.027 14.2 0.3 13 5.6 0.0 3.3 3 1 1 4 4 4 0 Thioredoxin domain Proteasome PF00227.21 KOS15983.1 - 5.3e-59 198.7 0.0 6.5e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS15983.1 - 2.9e-15 55.2 0.3 6.5e-15 54.1 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature His_Phos_1 PF00300.17 KOS15984.1 - 1e-20 74.4 0.0 1.6e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.12 KOS15985.1 - 6e-46 156.5 0.0 1.2e-45 155.5 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein Cyclin_N PF00134.18 KOS15986.1 - 1.3e-16 60.3 2.2 6.4e-16 58.0 0.6 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KOS15986.1 - 0.041 13.6 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Ribosomal_S5_C PF03719.10 KOS15987.1 - 1.3e-14 53.1 0.6 3.7e-14 51.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KOS15987.1 - 7.2e-14 51.2 1.3 1.7e-13 50.0 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Methyltransf_16 PF10294.4 KOS15988.1 - 4.7e-24 84.7 0.0 6.2e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase FRG1 PF06229.7 KOS15989.1 - 2.4e-17 63.0 0.5 4.6e-17 62.1 0.0 1.8 2 1 0 2 2 2 1 FRG1-like family Fascin PF06268.8 KOS15989.1 - 0.0011 18.9 0.0 0.017 15.2 0.0 2.5 2 1 1 3 3 3 1 Fascin domain DUF3748 PF12566.3 KOS15989.1 - 0.04 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Alg6_Alg8 PF03155.10 KOS15990.1 - 2.6e-113 379.3 18.1 1.4e-55 189.0 0.3 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family zf-RING_2 PF13639.1 KOS15991.1 - 5.9e-09 35.6 8.1 4.7e-08 32.7 3.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KOS15991.1 - 2.7e-06 27.3 3.6 9.8e-06 25.5 2.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KOS15991.1 - 1.5e-05 24.5 0.6 1.5e-05 24.5 0.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain PQ-loop PF04193.9 KOS15991.1 - 3.5e-05 23.2 5.0 9.3e-05 21.9 0.2 2.5 2 0 0 2 2 2 1 PQ loop repeat zf-C3HC4_3 PF13920.1 KOS15991.1 - 0.00051 19.6 2.1 0.00051 19.6 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS15991.1 - 0.00064 19.6 4.3 0.00064 19.6 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS15991.1 - 0.00096 18.7 4.9 0.0027 17.3 3.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KOS15991.1 - 0.0093 15.7 1.5 0.0093 15.7 1.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger UCH PF00443.24 KOS15992.1 - 1e-42 146.0 0.1 1.4e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS15992.1 - 1.5e-24 86.9 0.2 2.3e-24 86.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_5 PF12695.2 KOS15993.1 - 5.2e-05 23.0 0.1 9e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KOS15993.1 - 0.00054 19.4 4.4 0.00079 18.9 0.4 3.0 2 1 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.2 KOS15993.1 - 0.0018 18.1 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KOS15993.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 KOS15993.1 - 0.055 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1749 PF08538.5 KOS15993.1 - 0.081 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase PF07224.6 KOS15993.1 - 0.098 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Mad3_BUB1_I PF08311.7 KOS15994.1 - 8.8e-36 122.4 0.1 2e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KOS15994.1 - 3.6e-16 59.1 0.0 7.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS15994.1 - 0.0047 16.0 0.0 0.015 14.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase cwf18 PF08315.7 KOS15995.1 - 8.8e-24 84.4 1.3 1.1e-23 84.0 0.9 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Phage_portal_2 PF05136.8 KOS15995.1 - 0.021 13.3 0.4 0.027 13.0 0.2 1.3 1 1 0 1 1 1 0 Phage portal protein, lambda family XhlA PF10779.4 KOS15995.1 - 0.41 10.5 1.8 0.96 9.4 1.3 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Cyclin_N PF00134.18 KOS15996.1 - 1.3e-43 147.5 0.2 2.6e-43 146.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS15996.1 - 9.2e-24 83.6 0.0 2.4e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glutaredoxin PF00462.19 KOS15997.1 - 5.6e-17 61.4 0.0 8.6e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin zf-C2H2 PF00096.21 KOS15998.1 - 3.7e-07 30.1 8.3 0.00073 19.7 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS15998.1 - 0.00014 21.9 7.8 0.03 14.6 1.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KOS15998.1 - 0.0056 16.9 5.7 0.035 14.3 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KOS15998.1 - 0.023 14.5 2.7 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KOS15998.1 - 1.4 8.6 8.0 0.26 11.0 1.8 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TPR_19 PF14559.1 KOS15999.1 - 0.0008 19.6 0.2 0.0042 17.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR_3 PF13812.1 KOS15999.1 - 0.0012 19.0 6.8 2.9 8.4 0.1 4.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain TPR_7 PF13176.1 KOS15999.1 - 0.0057 16.3 0.1 17 5.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KOS15999.1 - 0.14 12.1 1.9 0.29 11.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KOS15999.1 - 0.15 12.0 1.7 13 5.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 KOS16000.1 - 2.8e-18 65.0 1.5 3.5e-10 39.3 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat bZIP_1 PF00170.16 KOS16000.1 - 3.8e-06 26.7 11.6 3.8e-06 26.7 8.0 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KOS16000.1 - 0.00025 20.8 8.5 0.00025 20.8 5.9 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Tropomyosin PF00261.15 KOS16000.1 - 0.023 13.8 3.6 0.038 13.0 2.5 1.2 1 0 0 1 1 1 0 Tropomyosin CLTH PF10607.4 KOS16000.1 - 0.023 14.3 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Toprim_3 PF13362.1 KOS16000.1 - 0.1 12.8 0.7 0.37 11.0 0.1 2.2 2 1 1 3 3 3 0 Toprim domain COG7 PF10191.4 KOS16001.1 - 3.9e-28 97.8 11.1 3.8e-18 64.8 3.7 3.1 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) HisKA_2 PF07568.7 KOS16001.1 - 0.11 12.4 0.7 2 8.3 0.0 2.9 2 1 0 2 2 2 0 Histidine kinase PDCD2_C PF04194.8 KOS16002.1 - 1.2e-30 106.2 0.1 1.2e-30 106.2 0.1 2.9 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Nucleoplasmin PF03066.10 KOS16002.1 - 0.87 9.0 6.2 1.9 8.0 4.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF2146 PF10220.4 KOS16002.1 - 1.6 6.6 4.6 2.2 6.1 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Lactamase_B_2 PF12706.2 KOS16003.1 - 4.3e-32 111.2 0.6 6.3e-32 110.6 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KOS16003.1 - 7.6e-15 54.9 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.19 KOS16004.1 - 3.1e-142 474.6 9.4 3.8e-142 474.3 6.5 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Brix PF04427.13 KOS16004.1 - 1.1e-54 184.9 0.0 1.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Brix domain Sua5_yciO_yrdC PF01300.13 KOS16004.1 - 0.0028 16.9 0.1 0.019 14.2 0.0 2.3 2 0 0 2 2 2 1 Telomere recombination DUF688 PF05097.7 KOS16004.1 - 0.0045 15.9 5.0 0.008 15.1 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF688) Nop14 PF04147.7 KOS16004.1 - 5.8 4.6 22.1 9.9 3.9 15.3 1.3 1 0 0 1 1 1 0 Nop14-like family CRM1_C PF08767.6 KOS16005.1 - 3.6e-127 423.7 0.0 3.6e-127 423.7 0.0 3.7 3 2 2 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 KOS16005.1 - 4.4e-40 136.9 2.7 4.4e-40 136.9 1.9 4.1 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KOS16005.1 - 1e-13 50.9 1.2 6.2e-13 48.4 0.8 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2367 PF10164.4 KOS16006.1 - 0.021 14.6 0.4 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) RrnaAD PF00398.15 KOS16007.1 - 2.5e-22 79.1 0.0 4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Med3 PF11593.3 KOS16008.1 - 3.8 6.6 4.3 5.5 6.1 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2207 PF09972.4 KOS16008.1 - 8 4.9 8.7 12 4.2 6.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATG11 PF10377.4 KOS16009.1 - 6.2e-17 61.6 0.2 5.2e-16 58.7 0.0 2.4 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 KOS16009.1 - 0.0071 15.1 5.9 0.69 8.6 0.0 3.1 3 0 0 3 3 3 2 Autophagy protein Apg17 DUF948 PF06103.6 KOS16009.1 - 0.016 15.0 3.2 11 5.9 0.0 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.11 KOS16009.1 - 9.9 6.2 18.2 0.18 11.8 1.3 3.7 4 0 0 4 4 4 0 Flagellar FliJ protein Glyoxal_oxid_N PF07250.6 KOS16010.1 - 1.4e-26 93.0 0.1 9.1e-23 80.5 0.0 3.5 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KOS16010.1 - 6.5e-20 71.0 0.2 1.7e-19 69.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Podoplanin PF05808.6 KOS16010.1 - 0.00067 19.2 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Podoplanin Kelch_4 PF13418.1 KOS16010.1 - 0.0075 16.0 2.9 1.3 8.8 0.1 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF912 PF06024.7 KOS16010.1 - 0.036 14.1 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mid2 PF04478.7 KOS16010.1 - 0.083 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.8 KOS16010.1 - 0.1 11.2 0.1 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.10 KOS16010.1 - 0.13 11.8 0.5 0.24 10.9 0.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 KOS16010.1 - 0.71 9.2 5.4 1.4 8.2 3.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AAA_23 PF13476.1 KOS16011.1 - 6.8 6.9 14.8 12 6.1 10.2 1.3 1 0 0 1 1 1 0 AAA domain zf-DNL PF05180.7 KOS16012.1 - 2.7e-28 97.4 0.1 3.5e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 DNL zinc finger Med22 PF06179.7 KOS16013.1 - 5.3e-15 55.3 1.5 8e-15 54.7 1.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SurA_N_2 PF13623.1 KOS16013.1 - 0.1 12.5 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 SurA N-terminal domain Cellulase PF00150.13 KOS16014.1 - 3.6e-17 62.4 4.5 5.9e-17 61.7 3.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNA_pol_Rpb4 PF03874.11 KOS16015.1 - 1.1e-14 54.4 0.4 1.4e-14 54.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1018 PF06252.7 KOS16015.1 - 0.01 16.3 0.2 0.017 15.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Ribonuc_L-PSP PF01042.16 KOS16016.1 - 5.6e-12 45.4 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP MMgT PF10270.4 KOS16017.1 - 7.1e-15 55.3 0.0 9.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF1279 PF06916.8 KOS16018.1 - 1.5e-16 60.4 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2927 PF11150.3 KOS16018.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) Asp PF00026.18 KOS16019.1 - 2.6e-47 161.6 7.4 7.5e-47 160.1 5.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KOS16019.1 - 2.8e-11 43.7 1.3 2.1e-05 24.9 0.1 2.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KOS16019.1 - 9e-05 22.0 0.5 0.00074 19.1 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal RVP PF00077.15 KOS16019.1 - 0.00035 20.4 0.1 0.5 10.3 0.0 3.1 3 0 0 3 3 3 2 Retroviral aspartyl protease TAXi_N PF14543.1 KOS16019.1 - 0.001 19.0 1.9 0.0061 16.5 0.7 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KOS16019.1 - 0.0067 16.2 0.0 0.97 9.3 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Abhydrolase_5 PF12695.2 KOS16020.1 - 7.3e-08 32.2 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KOS16020.1 - 8e-07 28.1 0.1 1.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KOS16020.1 - 1.3e-06 27.8 0.0 3.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KOS16020.1 - 0.0016 18.0 0.0 0.018 14.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KOS16020.1 - 0.0085 15.5 0.3 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Acetyltransf_1 PF00583.19 KOS16021.1 - 1.2e-12 47.6 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS16021.1 - 1.3e-05 25.2 0.0 3.5e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS16021.1 - 0.00026 21.1 0.1 0.0004 20.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS16021.1 - 0.02 14.7 0.5 0.027 14.3 0.3 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS16021.1 - 0.044 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS16021.1 - 0.067 13.0 0.2 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS16021.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein JAB PF01398.16 KOS16022.1 - 1.9e-07 30.8 0.6 1.1e-06 28.3 0.0 2.4 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NurA PF09376.5 KOS16022.1 - 0.19 11.1 0.2 0.79 9.1 0.1 1.8 2 0 0 2 2 2 0 NurA domain WD40 PF00400.27 KOS16024.1 - 1.8e-49 163.8 24.2 4.2e-11 42.2 0.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KOS16024.1 - 4e-12 45.6 0.4 4e-12 45.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 KOS16024.1 - 1.9e-07 29.6 9.5 0.07 11.2 0.0 5.1 1 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 KOS16024.1 - 3.3e-06 26.6 0.0 8.3e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 KOS16024.1 - 9.5e-05 22.5 4.4 7.9 6.9 0.0 5.6 5 1 1 6 6 6 1 PQQ-like domain BBS2_Mid PF14783.1 KOS16024.1 - 0.0015 18.2 0.0 0.041 13.6 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KOS16024.1 - 0.013 14.9 3.8 11 5.3 0.3 3.4 2 1 0 3 3 3 0 PQQ-like domain GTP_EFTU PF00009.22 KOS16025.1 - 8.2e-35 119.9 2.2 4.6e-34 117.5 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KOS16025.1 - 5.5e-25 87.3 0.2 1.3e-24 86.1 0.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KOS16025.1 - 1.3e-11 44.4 1.4 7.4e-06 25.9 0.0 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KOS16025.1 - 2.3e-05 24.3 0.0 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS16025.1 - 9.8e-05 22.8 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KOS16025.1 - 0.00015 21.1 0.1 0.00032 20.0 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 KOS16025.1 - 0.00026 20.4 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KOS16025.1 - 0.00073 18.8 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 KOS16025.1 - 0.0032 16.9 1.5 0.029 13.8 0.3 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KOS16025.1 - 0.0057 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KOS16025.1 - 0.15 11.2 0.0 0.4 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HMG_box PF00505.14 KOS16026.1 - 1.2e-25 89.5 2.5 1.6e-25 89.1 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KOS16026.1 - 1.4e-19 70.2 2.6 2e-19 69.7 1.8 1.2 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 KOS16026.1 - 0.0054 16.4 0.0 0.011 15.3 0.0 1.5 2 0 0 2 2 2 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 KOS16026.1 - 0.049 13.4 3.2 0.087 12.6 2.2 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 YABBY PF04690.8 KOS16026.1 - 0.15 12.3 0.6 0.19 11.9 0.1 1.5 1 1 0 1 1 1 0 YABBY protein Ras PF00071.17 KOS16027.1 - 7e-60 201.0 0.0 8.1e-60 200.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS16027.1 - 1.1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KOS16027.1 - 9.9e-15 54.2 0.0 1.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS16027.1 - 7.2e-08 31.8 0.0 9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS16027.1 - 2.3e-07 30.4 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KOS16027.1 - 3.9e-05 23.5 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Hpr_kinase_C PF07475.7 KOS16027.1 - 0.053 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 KOS16027.1 - 0.055 13.6 0.1 0.93 9.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain VWA_2 PF13519.1 KOS16028.1 - 2.6e-15 56.9 0.4 6.3e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KOS16028.1 - 4.3e-09 35.1 17.8 0.00065 19.0 0.7 4.2 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 KOS16028.1 - 6.1e-07 29.2 0.0 9.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KOS16028.1 - 1.2e-05 25.0 0.4 2.2e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PDH PF02153.12 KOS16028.1 - 0.0095 14.8 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase DUF243 PF03103.12 KOS16028.1 - 0.03 14.4 0.5 0.03 14.4 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF243) RNA_pol_Rpb2_6 PF00562.23 KOS16029.1 - 1.2e-121 406.1 0.0 2.2e-121 405.2 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KOS16029.1 - 8.4e-58 194.6 0.0 6.9e-57 191.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KOS16029.1 - 1.3e-37 129.0 0.3 4e-37 127.4 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KOS16029.1 - 1.3e-27 95.8 0.1 3.3e-27 94.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KOS16029.1 - 1.9e-23 82.0 0.2 1.3e-22 79.3 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KOS16029.1 - 2e-21 75.4 0.0 4.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KOS16029.1 - 2.6e-11 43.3 0.1 6.1e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ABC1 PF03109.11 KOS16030.1 - 1.2e-30 105.9 0.0 2.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 ABC1 family TFIIA PF03153.8 KOS16030.1 - 3.6 7.4 5.5 5.9 6.6 3.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PseudoU_synth_1 PF01416.15 KOS16031.1 - 7.7e-21 74.4 0.0 2.7e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase CTP-dep_RFKase PF01982.11 KOS16031.1 - 0.14 11.7 0.0 0.97 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF120 Ribosomal_L7Ae PF01248.21 KOS16032.1 - 4.4e-27 93.4 0.2 5.7e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KOS16032.1 - 0.0031 17.3 0.1 0.0034 17.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KOS16032.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 KOS16032.1 - 0.096 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 CTP_transf_2 PF01467.21 KOS16033.1 - 1.2e-15 57.9 0.0 2.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Anoctamin PF04547.7 KOS16035.1 - 4.5e-89 299.1 4.8 5.6e-89 298.8 3.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel CHCH PF06747.8 KOS16036.1 - 0.00022 21.0 12.5 0.00027 20.7 3.7 3.0 2 1 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 KOS16036.1 - 0.0031 17.2 11.1 0.21 11.4 2.9 3.0 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KOS16036.1 - 0.096 12.7 8.8 0.18 11.8 1.9 2.7 2 1 2 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 KOS16036.1 - 0.11 12.6 10.5 0.45 10.7 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) Ndufs5 PF10200.4 KOS16036.1 - 0.18 11.7 2.0 1.7 8.6 0.2 2.2 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Colipase-like PF15083.1 KOS16036.1 - 0.77 9.7 6.5 0.81 9.6 3.8 1.5 1 1 0 1 1 1 0 Colipase-like Pet191_N PF10203.4 KOS16036.1 - 0.98 9.5 10.2 7.5 6.6 5.2 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 KOS16036.1 - 2.2 8.2 8.8 0.82 9.6 0.3 3.2 2 2 1 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 KOS16036.1 - 3.2 7.6 8.0 3.3 7.6 0.4 3.1 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0203) DUF1470 PF07336.6 KOS16037.1 - 0.0053 17.0 8.1 0.056 13.7 2.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1470) KfrA_N PF11740.3 KOS16037.1 - 0.28 11.6 5.2 1 9.8 3.6 1.9 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term ApoO PF09769.4 KOS16038.1 - 1.1e-30 106.4 0.6 1.9e-30 105.6 0.4 1.4 2 0 0 2 2 2 1 Apolipoprotein O CLTH PF10607.4 KOS16039.1 - 1.9e-15 56.8 0.0 8.9e-14 51.3 0.0 2.1 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KOS16039.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 LisH DUF3572 PF12096.3 KOS16039.1 - 0.024 14.4 0.1 0.12 12.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3572) TPR_1 PF00515.23 KOS16040.1 - 0.0013 18.2 7.5 0.19 11.3 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS16040.1 - 0.01 15.7 7.7 0.042 13.7 0.5 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS16040.1 - 0.017 14.8 0.0 2.7 8.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KOS16040.1 - 0.018 14.9 0.3 8.4 6.4 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KOS16040.1 - 0.055 14.1 0.1 2.9 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KOS16040.1 - 0.063 12.9 4.6 0.24 11.0 0.1 3.3 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.1 KOS16040.1 - 0.076 13.7 0.0 0.77 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec8_exocyst PF04048.9 KOS16041.1 - 1.7e-24 86.0 0.0 3.6e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KOS16041.1 - 5.3e-06 25.5 0.0 9.8e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 KOS16041.1 - 0.018 14.8 1.3 0.066 13.0 0.0 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NotI PF12183.3 KOS16042.1 - 0.014 14.4 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Restriction endonuclease NotI FtsX PF02687.16 KOS16043.1 - 0.052 13.3 0.1 0.065 13.0 0.1 1.1 1 0 0 1 1 1 0 FtsX-like permease family Rpn3_C PF08375.6 KOS16044.1 - 5.2e-25 87.6 1.8 1.5e-24 86.1 1.3 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KOS16044.1 - 4e-22 78.5 0.3 1.6e-21 76.5 0.2 2.1 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 KOS16044.1 - 0.05 13.2 1.2 5 6.8 0.1 2.9 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 KOS16044.1 - 0.1 12.5 0.2 0.1 12.5 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTV_NS2 PF04514.7 KOS16044.1 - 0.28 10.0 1.7 0.47 9.2 1.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PMEI PF04043.10 KOS16044.1 - 0.49 10.2 4.2 14 5.5 0.1 2.9 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor TPR_12 PF13424.1 KOS16044.1 - 2.5 8.1 7.7 2 8.3 1.2 3.4 2 2 2 4 4 4 0 Tetratricopeptide repeat PCI PF01399.22 KOS16045.1 - 5.5e-12 45.9 0.5 4e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 PCI domain COX6C PF02937.10 KOS16045.1 - 0.17 11.7 2.4 1.4 8.8 1.1 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Sel1 PF08238.7 KOS16046.1 - 6.2e-10 39.3 16.5 9.6e-09 35.6 0.0 6.1 6 0 0 6 6 6 1 Sel1 repeat TPR_2 PF07719.12 KOS16046.1 - 0.0001 21.9 2.0 0.0023 17.7 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KOS16046.1 - 0.00086 18.8 0.1 0.015 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KOS16046.1 - 0.002 17.6 0.3 0.098 12.3 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 KOS16046.1 - 0.0072 16.0 0.4 0.084 12.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Exo_endo_phos PF03372.18 KOS16047.1 - 3.1e-20 73.1 0.0 5.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KOS16047.1 - 0.0011 18.8 5.9 0.046 13.6 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PFK PF00365.15 KOS16048.1 - 3.3e-158 524.9 1.0 1.7e-91 306.1 0.0 3.0 3 0 0 3 3 3 3 Phosphofructokinase L31 PF09784.4 KOS16049.1 - 9.8e-39 131.5 0.6 1.1e-38 131.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Myotub-related PF06602.9 KOS16050.1 - 1.4e-117 392.4 0.9 2e-117 391.9 0.7 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Radical_SAM PF04055.16 KOS16050.1 - 6e-16 59.0 0.1 1.5e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KOS16050.1 - 1.7e-10 40.7 0.2 3.4e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Y_phosphatase3 PF13350.1 KOS16050.1 - 0.0026 18.0 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS16050.1 - 0.0058 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KOS16050.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Acetyltransf_10 PF13673.1 KOS16050.1 - 0.023 14.8 0.0 0.088 12.9 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 KOS16051.1 - 5.4e-24 83.1 1.4 3.9e-09 36.0 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KOS16051.1 - 3e-05 23.6 0.5 0.0019 17.7 0.1 2.9 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 KOS16051.1 - 0.0045 17.2 1.1 2.6 8.4 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain Asp_Arg_Hydrox PF05118.10 KOS16051.1 - 0.08 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase PQQ PF01011.16 KOS16051.1 - 0.61 9.7 5.7 1.7 8.3 0.1 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat NAD_binding_7 PF13241.1 KOS16052.1 - 1.2e-25 89.7 0.0 1.7e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KOS16052.1 - 2.6e-18 65.0 0.0 4.3e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KOS16052.1 - 8.4e-14 50.2 0.3 1.5e-13 49.4 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 KOS16052.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 KOS16053.1 - 4.7e-20 70.6 12.1 8.4e-05 22.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-H2C2_2 PF13465.1 KOS16053.1 - 0.0093 16.2 2.1 0.47 10.8 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KOS16053.1 - 0.017 15.4 1.3 0.039 14.2 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16053.1 - 0.1 12.9 2.5 0.16 12.3 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger FAA_hydrolase PF01557.13 KOS16054.1 - 3.3e-56 190.1 0.0 4.2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Rad51 PF08423.6 KOS16055.1 - 2.6e-132 439.4 0.0 3.6e-132 438.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KOS16055.1 - 3.1e-14 52.8 0.1 4.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KOS16055.1 - 1.7e-08 33.9 0.2 2.2e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KOS16055.1 - 1.8e-08 34.3 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 KOS16055.1 - 2.1e-07 30.2 0.0 3.6e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 KOS16055.1 - 0.026 13.4 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KOS16055.1 - 0.25 10.1 1.8 0.6 8.8 1.0 1.7 1 1 1 2 2 2 0 PAXNEB protein Thymidylate_kin PF02223.12 KOS16056.1 - 2.6e-46 157.3 0.0 3.6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 KOS16056.1 - 1.1e-05 25.2 0.1 2.4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Abhydrolase_5 PF12695.2 KOS16056.1 - 4.3e-05 23.3 0.0 0.0001 22.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 KOS16056.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AAA_28 PF13521.1 KOS16056.1 - 0.0009 19.2 0.1 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KOS16056.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.13 KOS16056.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family LIP PF03583.9 KOS16056.1 - 0.083 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase DUF915 PF06028.6 KOS16056.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MRP-S28 PF10213.4 KOS16058.1 - 3.1e-31 108.1 0.0 7.9e-31 106.7 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein SpoIIE PF07228.7 KOS16059.1 - 4e-14 52.7 0.0 2.7e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KOS16059.1 - 5.5e-08 32.4 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KOS16059.1 - 0.1 12.0 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C NIF PF03031.13 KOS16061.1 - 1.8e-41 141.4 0.0 2.5e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PCI PF01399.22 KOS16062.1 - 1.1e-13 51.4 0.0 9.4e-13 48.4 0.0 2.5 2 1 1 3 3 3 1 PCI domain TFIIE_alpha PF02002.12 KOS16062.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit P21-Arc PF04062.9 KOS16063.1 - 7.6e-70 234.2 0.0 8.4e-70 234.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit He_PIG PF05345.7 KOS16064.1 - 8.7e-14 51.2 5.8 3.2e-08 33.4 0.0 4.1 3 0 0 3 3 3 3 Putative Ig domain Vps36_ESCRT-II PF11605.3 KOS16065.1 - 0.0038 17.0 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF2392 PF10288.4 KOS16067.1 - 1.5e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 KOS16067.1 - 1.7 8.5 5.2 12 5.7 0.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon Herpes_UL32 PF06070.6 KOS16068.1 - 0.69 8.2 7.3 0.78 8.1 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 CUE PF02845.11 KOS16069.1 - 3.5e-09 35.9 0.0 5.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 KOS16069.1 - 9.2e-05 21.9 1.7 0.00015 21.3 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 DUF1296 PF06972.6 KOS16069.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-primase PF09329.6 KOS16070.1 - 8.8e-09 34.8 0.7 1.6e-08 33.9 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger WRC PF08879.5 KOS16070.1 - 0.012 15.3 0.3 0.029 14.0 0.2 1.7 1 0 0 1 1 1 0 WRC zf-C3Hc3H PF13891.1 KOS16070.1 - 0.015 15.3 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 Potential DNA-binding domain PROCN PF08083.6 KOS16071.1 - 3.2e-209 694.4 6.0 4.8e-209 693.8 4.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KOS16071.1 - 5.7e-126 418.4 0.5 9.4e-126 417.7 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KOS16071.1 - 2.8e-90 299.8 0.6 7.6e-90 298.4 0.4 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KOS16071.1 - 2.7e-79 264.1 5.4 3e-79 263.9 1.8 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KOS16071.1 - 1.4e-66 222.2 0.0 2.5e-66 221.3 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KOS16071.1 - 1.7e-41 139.9 0.2 3.9e-41 138.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KOS16071.1 - 7.6e-33 112.8 0.0 1.5e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 KOS16071.1 - 7.4e-05 22.4 0.0 0.00021 21.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SCP-1 PF05483.7 KOS16071.1 - 0.26 8.9 0.1 0.39 8.4 0.0 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) zf-rbx1 PF12678.2 KOS16072.1 - 3.3e-25 87.9 7.5 4.1e-25 87.6 5.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KOS16072.1 - 6.2e-14 51.6 6.2 1e-13 50.9 4.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KOS16072.1 - 4.6e-07 29.5 4.6 4.6e-07 29.5 3.2 1.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KOS16072.1 - 0.00015 21.7 1.6 0.00028 20.8 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KOS16072.1 - 0.00095 18.7 5.1 0.0017 17.9 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KOS16072.1 - 0.003 17.1 1.0 0.0046 16.5 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KOS16072.1 - 0.016 15.1 1.8 0.016 15.1 1.3 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_6 PF14835.1 KOS16072.1 - 0.079 12.7 1.3 0.099 12.4 0.6 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KOS16072.1 - 0.093 12.4 2.4 0.14 11.8 1.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Glutaredoxin PF00462.19 KOS16073.1 - 2e-12 46.8 0.0 3.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KOS16073.1 - 0.0054 16.9 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Acp26Ab PF05777.7 KOS16073.1 - 0.076 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Lipase_3 PF01764.20 KOS16074.1 - 1.1e-12 47.7 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) ATE_C PF04377.10 KOS16075.1 - 2.8e-44 150.2 0.4 4.5e-44 149.6 0.3 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KOS16075.1 - 1e-23 82.9 2.5 2.3e-23 81.8 1.8 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus FA_desaturase PF00487.19 KOS16076.1 - 7.7e-17 61.5 17.4 7.7e-17 61.5 12.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KOS16076.1 - 2.1e-15 56.2 0.0 3.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CHCC PF10276.4 KOS16077.1 - 2e-10 40.3 0.2 4.7e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger domain ATP_bind_4 PF01902.12 KOS16078.1 - 5.2e-35 120.8 0.0 4.5e-25 88.3 0.0 2.2 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KOS16078.1 - 4.2e-15 55.5 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 KOS16078.1 - 0.00051 18.7 0.0 0.00076 18.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Aminotran_5 PF00266.14 KOS16079.1 - 6.9e-90 301.4 0.0 1.5e-89 300.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V zf-HC5HC2H_2 PF13832.1 KOS16080.1 - 9.9e-35 118.8 6.3 9.9e-35 118.8 4.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KOS16080.1 - 1.7e-26 92.1 4.0 1.7e-26 92.1 2.8 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 KOS16080.1 - 4.1e-23 81.0 0.1 8.8e-23 80.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.4 KOS16080.1 - 4.9e-22 78.8 0.2 1.1e-21 77.7 0.1 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 KOS16080.1 - 8.4e-15 53.8 2.9 8.4e-15 53.8 2.0 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KOS16080.1 - 2.2e-09 36.8 25.3 1.4e-08 34.2 6.5 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KOS16080.1 - 0.0024 17.5 0.9 0.0024 17.5 0.7 2.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KOS16080.1 - 3.9 7.2 18.0 3 7.6 3.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KOS16080.1 - 5.9 6.9 26.3 0.1 12.6 4.8 3.2 3 0 0 3 3 3 0 RING-like domain DUF3402 PF11882.3 KOS16081.1 - 1e-116 390.3 0.0 1.4e-116 389.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KOS16081.1 - 2.3e-43 148.1 0.0 3.7e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein GEMIN8 PF15348.1 KOS16081.1 - 0.02 14.9 0.0 1.6 8.7 0.0 2.6 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 DUF3808 PF10300.4 KOS16082.1 - 1.6e-85 287.4 0.7 4.2e-85 286.0 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KOS16082.1 - 1.1e-05 25.0 9.6 0.052 13.1 0.1 3.8 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 KOS16082.1 - 5.7e-05 22.9 3.5 0.067 13.1 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KOS16082.1 - 6.6e-05 22.5 8.6 0.062 13.2 0.3 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KOS16082.1 - 7.9e-05 22.1 3.2 0.058 13.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KOS16082.1 - 8.9e-05 22.7 0.5 1.7 9.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KOS16082.1 - 0.00063 19.2 3.7 0.58 9.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KOS16082.1 - 0.00064 20.0 0.6 0.49 10.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS16082.1 - 0.025 14.3 2.5 12 6.0 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat HemX PF04375.9 KOS16082.1 - 0.054 12.0 1.8 0.085 11.4 1.3 1.2 1 0 0 1 1 1 0 HemX tRNA-synt_1e PF01406.14 KOS16083.1 - 8e-125 415.9 0.0 1.2e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KOS16083.1 - 6.2e-09 35.0 1.1 8.3e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 KOS16083.1 - 7.4e-06 24.8 0.7 0.0022 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.17 KOS16083.1 - 1.1e-05 23.7 0.4 0.0031 15.6 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KOS16083.1 - 0.002 18.3 1.6 0.003 17.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.13 KOS16083.1 - 0.066 11.8 0.2 5.3 5.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) EGL-1 PF11430.3 KOS16083.1 - 0.58 9.8 2.9 0.48 10.0 0.8 1.8 2 0 0 2 2 2 0 Programmed cell death activator EGL-1 peroxidase PF00141.18 KOS16084.1 - 2.5e-51 174.3 0.0 3.5e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 KOS16084.1 - 0.12 11.7 0.1 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB TPK_catalytic PF04263.11 KOS16084.1 - 0.16 11.5 0.3 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain F_bP_aldolase PF01116.15 KOS16085.1 - 6.9e-99 330.5 0.0 7.8e-99 330.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pil1 PF13805.1 KOS16086.1 - 4.4e-19 68.6 2.1 6.9e-19 68.0 1.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2730 PF10805.3 KOS16086.1 - 0.0026 17.4 1.3 0.0056 16.3 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Myosin_tail_1 PF01576.14 KOS16086.1 - 0.017 12.8 2.9 0.024 12.4 2.0 1.2 1 0 0 1 1 1 0 Myosin tail Phage_GP20 PF06810.6 KOS16086.1 - 0.017 14.5 0.6 0.039 13.3 0.4 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 KOS16086.1 - 0.026 13.7 2.2 0.052 12.7 1.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 KOS16086.1 - 0.05 13.4 0.4 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 KOS16086.1 - 0.14 11.7 4.0 0.39 10.2 0.7 2.2 1 1 1 2 2 2 0 IncA protein Erp_C PF06780.6 KOS16086.1 - 0.3 10.9 3.2 1.5 8.6 0.8 2.1 2 0 0 2 2 2 0 Erp protein C-terminus Tropomyosin_1 PF12718.2 KOS16086.1 - 0.44 10.3 5.4 0.12 12.1 1.2 1.9 2 0 0 2 2 2 0 Tropomyosin like Vps51 PF08700.6 KOS16086.1 - 0.78 9.6 4.5 2 8.3 0.9 2.4 2 0 0 2 2 2 0 Vps51/Vps67 CENP-Q PF13094.1 KOS16086.1 - 4.3 7.3 9.7 1.8 8.5 4.1 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 KOS16086.1 - 6.8 6.5 8.1 0.39 10.5 0.4 2.4 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Glyoxalase PF00903.20 KOS16087.1 - 0.041 13.8 6.1 0.056 13.4 3.6 1.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WI12 PF07107.6 KOS16087.1 - 1 9.2 6.3 0.2 11.5 0.7 2.4 2 2 0 2 2 2 0 Wound-induced protein WI12 zf-Tim10_DDP PF02953.10 KOS16088.1 - 1.5e-20 72.2 0.5 1.8e-20 71.9 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1258 PF06869.7 KOS16088.1 - 0.059 12.4 0.1 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF59 PF01883.14 KOS16089.1 - 3.7e-08 33.2 0.0 8.2e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 Transket_pyr PF02779.19 KOS16090.1 - 5.1e-49 166.1 0.0 7.2e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KOS16090.1 - 8.2e-40 135.5 0.0 1.6e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain GLTP PF08718.6 KOS16091.1 - 1.9e-41 141.5 0.0 2.8e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF1798 PF08807.5 KOS16091.1 - 0.0064 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) DUF2497 PF10691.4 KOS16091.1 - 0.044 13.7 0.1 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Chitin_synth_2 PF03142.10 KOS16092.1 - 1.5e-235 782.5 0.0 2.2e-235 782.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KOS16092.1 - 7e-101 338.3 0.0 1.1e-100 337.7 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 KOS16092.1 - 9.7e-21 74.6 0.0 5.3e-15 55.8 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS16092.1 - 7.2e-16 58.4 2.4 4.2e-15 55.9 1.7 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KOS16092.1 - 2.2e-13 49.7 1.1 1.5e-12 47.0 0.5 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KOS16092.1 - 9.3e-12 44.5 0.0 1.8e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KOS16092.1 - 3.8e-06 26.2 0.1 0.00031 20.0 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS16092.1 - 0.00023 20.8 0.0 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 PXA PF02194.10 KOS16093.1 - 4.8e-29 101.2 0.2 9.6e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 PXA domain RGS PF00615.14 KOS16093.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain Xan_ur_permease PF00860.15 KOS16093.1 - 0.0029 16.1 0.1 0.0042 15.6 0.1 1.2 1 0 0 1 1 1 1 Permease family FMO-like PF00743.14 KOS16094.1 - 6.7e-34 116.9 0.0 3e-23 81.8 0.0 3.3 4 0 0 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KOS16094.1 - 1.4e-17 64.4 0.0 4.5e-17 62.7 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KOS16094.1 - 2e-08 34.3 0.0 4.9e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS16094.1 - 1e-07 31.8 0.1 3.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KOS16094.1 - 3.2e-06 26.3 0.3 2.8e-05 23.1 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KOS16094.1 - 6.7e-06 25.9 0.5 0.0012 18.5 0.6 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KOS16094.1 - 0.00082 18.5 0.3 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KOS16094.1 - 0.022 13.8 0.4 0.07 12.2 0.3 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 KOS16094.1 - 0.022 13.6 0.1 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KOS16094.1 - 0.029 12.8 1.7 0.044 12.2 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KOS16094.1 - 0.11 11.4 1.7 0.17 10.8 1.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KOS16094.1 - 0.14 12.6 0.9 0.23 11.8 0.1 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KOS16094.1 - 0.44 9.1 1.7 0.68 8.4 1.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 KOS16094.1 - 0.56 9.0 7.6 0.18 10.7 2.7 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KOS16094.1 - 1.5 7.6 3.0 1.9 7.2 2.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NIPSNAP PF07978.8 KOS16095.1 - 1.5e-21 76.3 5.5 2.4e-20 72.3 1.3 2.2 2 0 0 2 2 2 2 NIPSNAP DUF718 PF05336.8 KOS16095.1 - 0.00096 18.9 1.1 0.035 13.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF718) LRR_6 PF13516.1 KOS16096.1 - 3.1e-14 51.3 4.2 0.59 10.3 0.0 7.7 7 1 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.2 KOS16096.1 - 2.1e-05 24.0 9.7 0.51 10.0 0.0 5.8 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KOS16096.1 - 0.00053 19.6 10.8 4.2 7.7 0.1 7.2 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 KOS16096.1 - 0.0016 18.1 13.7 0.025 14.3 0.4 5.4 4 2 1 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 KOS16096.1 - 1.9 9.0 12.9 8.8 7.0 0.2 6.1 7 0 0 7 7 7 0 Leucine rich repeat Nucleoplasmin PF03066.10 KOS16096.1 - 6.5 6.2 13.6 13 5.3 9.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin SNARE PF05739.14 KOS16097.1 - 5.1e-13 48.4 2.8 5.1e-13 48.4 1.9 1.7 2 0 0 2 2 2 1 SNARE domain FGE-sulfatase PF03781.11 KOS16097.1 - 0.053 12.8 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 MPC PF03650.8 KOS16098.1 - 5.3e-42 142.5 0.1 5.8e-42 142.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Telomere_reg-2 PF10193.4 KOS16099.1 - 1.3e-24 86.6 0.0 6.3e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Telomere length regulation protein DNA_pol_phi PF04931.8 KOS16100.1 - 6.8e-68 229.2 34.2 1.3e-66 225.0 23.7 2.6 1 1 0 1 1 1 1 DNA polymerase phi Daxx PF03344.10 KOS16100.1 - 0.099 11.1 23.0 0.24 9.8 15.9 1.6 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 KOS16100.1 - 0.6 8.1 18.4 1.3 7.0 12.7 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fip1 PF05182.8 KOS16101.1 - 6.8e-22 76.4 1.0 1.2e-21 75.7 0.7 1.4 1 0 0 1 1 1 1 Fip1 motif Fasciclin PF02469.17 KOS16102.1 - 4.8e-54 181.7 0.0 4.1e-14 52.6 0.0 5.3 5 0 0 5 5 5 5 Fasciclin domain DUF4381 PF14316.1 KOS16102.1 - 0.91 9.6 3.7 1.7 8.7 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) TRAPP PF04051.11 KOS16103.1 - 1.3e-36 125.3 0.0 1.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phosphoprotein PF00922.12 KOS16103.1 - 0.57 9.3 7.6 0.2 10.8 2.6 1.8 1 1 1 2 2 2 0 Vesiculovirus phosphoprotein CRAL_TRIO PF00650.15 KOS16104.1 - 1.1e-34 119.2 0.2 2.3e-34 118.1 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS16104.1 - 2.3e-12 46.8 1.0 7.3e-12 45.2 0.7 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain 2-Hacid_dh_C PF02826.14 KOS16105.1 - 2.4e-50 170.1 0.0 3.6e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KOS16105.1 - 2.4e-16 59.3 0.0 3.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KOS16105.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 KOS16105.1 - 0.036 13.9 0.5 0.34 10.7 0.1 2.6 2 2 1 3 3 3 0 short chain dehydrogenase Shikimate_DH PF01488.15 KOS16105.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sybindin PF04099.7 KOS16106.1 - 2.3e-37 127.8 0.0 2.5e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KOS16106.1 - 8.7e-07 28.8 0.0 8.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NOGCT PF08155.6 KOS16107.1 - 1.8e-29 101.1 2.3 1.8e-29 101.1 1.6 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KOS16107.1 - 1.3e-28 98.5 0.1 3.1e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KOS16107.1 - 8.3e-18 64.4 0.0 2.4e-17 62.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KOS16107.1 - 5.8e-09 35.4 0.0 9.9e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KOS16107.1 - 0.0003 21.2 0.0 0.00083 19.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KOS16107.1 - 0.0037 16.4 0.0 0.035 13.2 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KOS16107.1 - 0.0042 16.9 2.1 1.7 8.4 0.0 3.5 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.11 KOS16107.1 - 0.0042 16.2 0.0 0.01 14.9 0.0 1.7 1 0 0 1 1 1 1 AIG1 family LEA_6 PF10714.4 KOS16107.1 - 0.034 13.9 1.6 0.065 13.0 1.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Ras PF00071.17 KOS16107.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Ras family GTP_EFTU PF00009.22 KOS16107.1 - 0.15 11.4 3.1 0.17 11.2 0.2 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Sugar_tr PF00083.19 KOS16108.1 - 2.1e-85 286.9 23.2 2.5e-85 286.7 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS16108.1 - 1.5e-17 63.3 28.3 1.5e-17 63.3 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KOS16109.1 - 5.9e-153 509.5 0.3 6.7e-153 509.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.16 KOS16110.1 - 1.4e-77 260.7 0.0 1.7e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Glyco_hydro_10 PF00331.15 KOS16110.1 - 0.089 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 COPIIcoated_ERV PF07970.7 KOS16111.1 - 4.9e-35 121.1 0.1 7.2e-35 120.6 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KOS16111.1 - 4.4e-21 74.6 0.0 9.1e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.24 KOS16112.1 - 3.1e-91 302.4 0.0 1.5e-46 157.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS16112.1 - 1.4e-13 50.4 0.0 3e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KOS16112.1 - 2.4e-11 43.8 0.0 0.00027 20.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KOS16112.1 - 1.4e-10 41.4 0.7 0.0022 18.1 0.0 4.9 2 2 2 4 4 4 2 AAA domain AAA_16 PF13191.1 KOS16112.1 - 3.2e-10 40.2 3.2 0.0012 18.9 0.0 4.1 3 2 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 KOS16112.1 - 4.7e-10 40.3 0.0 6.9e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KOS16112.1 - 1.4e-09 37.8 0.5 0.0014 18.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KOS16112.1 - 2.7e-09 37.0 0.0 0.002 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KOS16112.1 - 3e-08 32.8 0.0 0.00061 18.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KOS16112.1 - 1.2e-07 31.6 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KOS16112.1 - 1.5e-07 30.8 0.4 0.014 14.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS16112.1 - 3e-07 30.5 0.0 0.028 14.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KOS16112.1 - 6.2e-07 29.0 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KOS16112.1 - 8e-07 29.1 0.0 0.032 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KOS16112.1 - 1.4e-06 27.5 0.0 0.0097 15.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KOS16112.1 - 4.5e-06 26.3 3.5 0.016 14.9 0.0 4.1 4 0 0 4 4 3 2 Part of AAA domain NACHT PF05729.7 KOS16112.1 - 6.1e-06 25.9 1.0 0.48 10.0 0.0 3.7 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 KOS16112.1 - 1.1e-05 25.0 0.0 0.047 13.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KOS16112.1 - 1.3e-05 24.6 10.9 0.16 11.3 0.1 5.1 3 2 2 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.1 KOS16112.1 - 1.7e-05 24.9 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KOS16112.1 - 3.3e-05 24.2 0.2 0.047 13.9 0.0 3.1 3 0 0 3 3 2 1 ABC transporter KaiC PF06745.8 KOS16112.1 - 5.6e-05 22.3 0.1 1.2 8.2 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 KOS16112.1 - 7.2e-05 23.0 0.0 0.62 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.1 KOS16112.1 - 0.00018 21.4 0.0 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 KOS16112.1 - 0.0003 20.4 0.0 0.61 9.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.17 KOS16112.1 - 0.0007 19.4 0.0 0.97 9.2 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 KOS16112.1 - 0.00082 18.8 0.1 0.29 10.6 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain Rad17 PF03215.10 KOS16112.1 - 0.0021 16.8 0.0 0.66 8.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PhoH PF02562.11 KOS16112.1 - 0.0021 17.3 0.2 0.83 8.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.12 KOS16112.1 - 0.0024 16.8 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KOS16112.1 - 0.0038 17.0 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 KOS16112.1 - 0.0058 15.5 0.0 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 KOS16112.1 - 0.006 15.4 0.2 0.28 9.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.1 KOS16112.1 - 0.011 15.3 0.0 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KOS16112.1 - 0.016 14.9 0.0 1.4 8.5 0.0 3.3 2 2 2 4 4 4 0 Archaeal ATPase AAA_24 PF13479.1 KOS16112.1 - 0.018 14.6 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KOS16112.1 - 0.026 14.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AFG1_ATPase PF03969.11 KOS16112.1 - 0.027 13.2 0.0 4.2 6.0 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 KOS16112.1 - 0.039 13.5 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KOS16112.1 - 0.11 12.1 0.2 2.3 7.9 0.0 3.0 4 0 0 4 4 2 0 NTPase PduV-EutP PF10662.4 KOS16112.1 - 0.18 11.2 0.0 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KOS16113.1 - 1e-49 168.0 0.0 2.3e-42 144.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS16113.1 - 7.1e-10 39.1 4.0 2.8e-06 27.4 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain Sigma54_activ_2 PF14532.1 KOS16113.1 - 2.7e-06 27.4 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KOS16113.1 - 6.5e-06 25.6 0.0 4.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 KOS16113.1 - 9.6e-06 25.7 0.0 0.0074 16.4 0.0 3.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KOS16113.1 - 1.4e-05 24.7 0.7 0.0057 16.3 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KOS16113.1 - 2.6e-05 24.2 0.0 6.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KOS16113.1 - 7.1e-05 22.5 0.2 0.024 14.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 KOS16113.1 - 0.00033 20.5 0.1 0.00081 19.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain AAA_18 PF13238.1 KOS16113.1 - 0.0016 18.7 3.7 0.022 15.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.21 KOS16113.1 - 0.0035 16.8 0.0 1.3 8.4 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.1 KOS16113.1 - 0.0036 16.7 0.1 0.016 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS16113.1 - 0.0054 16.6 1.7 0.028 14.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 KOS16113.1 - 0.0065 15.3 0.0 0.78 8.5 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Torsin PF06309.6 KOS16113.1 - 0.0078 16.1 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 1 Torsin Mg_chelatase PF01078.16 KOS16113.1 - 0.013 14.7 0.2 0.21 10.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KOS16113.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 KOS16113.1 - 0.02 15.7 0.0 0.02 15.7 0.0 3.1 4 0 0 4 4 2 0 AAA domain NB-ARC PF00931.17 KOS16113.1 - 0.033 13.0 0.1 6.9 5.4 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain TIP49 PF06068.8 KOS16113.1 - 0.038 12.7 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus DUF2075 PF09848.4 KOS16113.1 - 0.052 12.5 0.0 0.16 10.8 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KOS16113.1 - 0.094 11.9 0.0 0.38 9.9 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein Glu-tRNAGln PF02686.10 KOS16113.1 - 0.47 10.2 4.0 4.6 7.1 0.1 2.9 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit AAA_11 PF13086.1 KOS16113.1 - 1.7 8.1 0.0 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain WD40 PF00400.27 KOS16114.1 - 1.2e-43 145.4 27.4 2e-06 27.4 0.0 10.2 10 0 0 10 10 10 9 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KOS16114.1 - 3.7e-08 33.5 0.1 7.5e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Cytidylyltransferase NIF3 PF01784.13 KOS16115.1 - 8.5e-56 189.2 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Nitro_FeMo-Co PF02579.12 KOS16115.1 - 0.1 12.6 0.0 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor COX5A PF02284.11 KOS16116.1 - 1.5e-39 134.3 0.3 2e-39 133.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LSM PF01423.17 KOS16117.1 - 1.4e-12 46.9 0.0 1.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KOS16117.1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Tail_tube PF10618.4 KOS16117.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein Mito_carr PF00153.22 KOS16118.1 - 1.2e-66 220.4 1.8 3.2e-25 87.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L28e PF01778.12 KOS16119.1 - 3.4e-34 117.7 0.1 4.3e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family FAD_binding_1 PF00667.15 KOS16120.1 - 1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KOS16120.1 - 3.1e-31 108.2 0.0 5.8e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KOS16120.1 - 6.4e-13 49.2 0.0 2.5e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 KOS16120.1 - 0.0027 17.1 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin domain FAD_binding_6 PF00970.19 KOS16120.1 - 0.066 13.3 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain OB_NTP_bind PF07717.11 KOS16121.1 - 9.5e-28 96.3 0.1 2.6e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KOS16121.1 - 1.3e-25 89.3 0.2 5.3e-25 87.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS16121.1 - 1.5e-13 50.3 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS16121.1 - 2.5e-05 23.8 0.0 5.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KOS16121.1 - 0.00012 21.0 0.0 0.00025 20.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KOS16121.1 - 0.0005 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KOS16121.1 - 0.002 17.6 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KOS16121.1 - 0.013 15.2 0.1 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KOS16121.1 - 0.023 13.5 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KOS16121.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KOS16121.1 - 0.16 12.2 1.9 0.32 11.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter MT-A70 PF05063.9 KOS16122.1 - 7.2e-41 139.6 0.0 1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Arf PF00025.16 KOS16123.1 - 9e-35 119.4 0.1 7.5e-22 77.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KOS16123.1 - 1.3e-11 44.1 0.0 2e-08 33.8 0.0 2.0 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KOS16123.1 - 3.5e-08 33.3 0.0 6.2e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KOS16123.1 - 9.4e-07 29.3 0.0 3.6e-05 24.2 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein SRPRB PF09439.5 KOS16123.1 - 3e-05 23.3 0.0 7.4e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KOS16123.1 - 5.8e-05 22.3 0.0 7.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KOS16123.1 - 0.00098 17.9 0.0 0.0065 15.2 0.0 2.1 3 0 0 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 KOS16123.1 - 0.0016 17.8 0.0 0.55 9.6 0.0 2.2 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KOS16123.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 KOS16123.1 - 0.044 14.0 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KOS16123.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SUV3_C PF12513.3 KOS16124.1 - 7.9e-15 54.0 0.2 1.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KOS16124.1 - 2.4e-12 46.5 0.0 5.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1263 PF06882.7 KOS16124.1 - 0.029 13.9 0.0 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1263) Ssl1 PF04056.9 KOS16125.1 - 7.5e-59 198.5 0.0 1.2e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KOS16125.1 - 7.7e-17 61.0 7.8 7.7e-17 61.0 5.4 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KOS16125.1 - 5e-08 33.2 0.1 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-HIT PF04438.11 KOS16125.1 - 4.3 7.0 21.6 0.39 10.4 2.0 3.5 4 0 0 4 4 4 0 HIT zinc finger zf-RING_2 PF13639.1 KOS16125.1 - 5.1 7.0 19.5 3.2 7.6 5.2 2.7 2 0 0 2 2 2 0 Ring finger domain RRM_1 PF00076.17 KOS16126.1 - 5.4e-17 61.1 0.0 9.3e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSS1_SEM1 PF05160.8 KOS16126.1 - 4.4e-16 58.4 11.0 8.7e-10 38.2 0.8 2.5 2 0 0 2 2 2 2 DSS1/SEM1 family RRM_6 PF14259.1 KOS16126.1 - 8.8e-13 48.0 0.0 2.3e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16126.1 - 1.6e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cgr1 PF03879.9 KOS16127.1 - 5.6e-17 61.8 26.8 6.1e-17 61.7 18.6 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2514 PF10721.4 KOS16127.1 - 0.15 11.7 18.8 0.18 11.5 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Caudo_TAP PF02413.12 KOS16127.1 - 0.22 11.7 8.0 0.27 11.4 5.6 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein SPATIAL PF15256.1 KOS16127.1 - 1.1 9.3 8.4 1.2 9.1 5.8 1.0 1 0 0 1 1 1 0 SPATIAL PBP_sp32 PF07222.7 KOS16127.1 - 1.3 8.1 6.5 1.4 8.0 4.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAF-1_p150 PF11600.3 KOS16127.1 - 3.3 7.0 24.9 3.8 6.8 17.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 KOS16127.1 - 3.7 6.4 8.9 4 6.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KOS16127.1 - 4.4 6.2 9.5 4.6 6.1 6.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2058 PF09831.4 KOS16127.1 - 5 6.9 14.9 5.5 6.8 10.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Nop53 PF07767.6 KOS16127.1 - 5.5 5.8 21.8 6.1 5.7 15.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDRGK PF09756.4 KOS16127.1 - 8.1 5.8 22.8 11 5.3 15.8 1.2 1 0 0 1 1 1 0 DDRGK domain LSM PF01423.17 KOS16128.1 - 7.6e-16 57.4 0.4 9.7e-16 57.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_16 PF10294.4 KOS16129.1 - 3.3e-36 124.3 0.0 4.1e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS16129.1 - 0.00014 22.3 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS16129.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KOS16129.1 - 0.054 12.8 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Lactamase_B_2 PF12706.2 KOS16130.1 - 2.3e-15 56.6 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS16130.1 - 3.4e-10 39.8 0.0 5.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 KOS16131.1 - 3.3e-72 242.7 0.0 3.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16131.1 - 1e-31 109.9 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KOS16131.1 - 0.00044 19.3 0.1 0.00078 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KOS16131.1 - 0.0026 17.5 0.6 0.059 13.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS16131.1 - 0.0036 16.3 0.0 0.012 14.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like YukC PF10140.4 KOS16131.1 - 0.082 11.4 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC E1-E2_ATPase PF00122.15 KOS16132.1 - 1e-68 230.8 1.6 1e-68 230.8 1.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KOS16132.1 - 4.3e-50 169.7 6.9 6.8e-50 169.1 3.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KOS16132.1 - 1.7e-33 116.8 0.0 1.3e-32 114.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS16132.1 - 1.3e-19 69.3 0.1 2.9e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KOS16132.1 - 1.3e-18 66.7 0.0 2.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KOS16132.1 - 2.1e-15 57.4 0.0 8.2e-15 55.4 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KOS16132.1 - 1.4e-09 37.9 1.3 7.8e-08 32.2 1.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KOS16132.1 - 0.0089 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CK_II_beta PF01214.13 KOS16133.1 - 5.5e-72 241.1 0.0 6.5e-72 240.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit eIF-5a PF01287.15 KOS16134.1 - 1.7e-27 95.1 0.2 2.3e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KOS16134.1 - 0.00015 21.3 0.5 0.00026 20.5 0.4 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KOS16134.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Sec1 PF00995.18 KOS16135.1 - 3.7e-123 412.1 0.0 4.2e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2798 PF11391.3 KOS16135.1 - 0.069 12.9 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) LUC7 PF03194.10 KOS16136.1 - 8.1e-71 238.5 1.3 9.4e-71 238.3 0.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Mnd1 PF03962.10 KOS16136.1 - 0.0066 16.1 1.4 0.0084 15.7 1.0 1.3 1 0 0 1 1 1 1 Mnd1 family Bombinin PF05298.6 KOS16136.1 - 0.03 13.7 0.3 0.05 13.0 0.2 1.4 1 0 0 1 1 1 0 Bombinin APG6 PF04111.7 KOS16136.1 - 0.043 12.8 2.5 0.051 12.6 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DNA_Packaging PF11053.3 KOS16136.1 - 0.069 12.7 1.5 0.11 12.0 1.0 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme YgbB PF02542.11 KOS16136.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 YgbB family V_ATPase_I PF01496.14 KOS16136.1 - 0.14 9.9 1.4 0.17 9.7 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.5 KOS16136.1 - 0.33 11.0 2.6 0.55 10.3 1.6 1.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region B56 PF01603.15 KOS16137.1 - 1.2e-167 557.6 5.1 1.5e-167 557.3 3.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pyrophosphatase PF00719.14 KOS16138.1 - 6.2e-53 178.4 0.1 8.3e-53 178.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase CSTF2_hinge PF14327.1 KOS16139.1 - 8.2e-29 99.5 3.8 8.2e-29 99.5 2.6 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KOS16139.1 - 2.3e-22 78.4 0.1 3.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16139.1 - 1.1e-15 57.3 0.0 2.5e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KOS16139.1 - 2.9e-09 36.0 8.2 2.9e-09 36.0 5.7 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KOS16139.1 - 2.2e-08 33.7 0.0 3.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DASH_Spc19 PF08287.6 KOS16140.1 - 3.1e-22 78.8 3.0 4.1e-22 78.4 2.1 1.2 1 0 0 1 1 1 1 Spc19 DivIC PF04977.10 KOS16140.1 - 0.086 12.3 0.4 0.086 12.3 0.3 2.3 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.13 KOS16140.1 - 0.16 11.6 2.6 2.7 7.7 0.8 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cortex-I_coil PF09304.5 KOS16140.1 - 0.17 11.9 6.2 0.39 10.7 0.2 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil SlyX PF04102.7 KOS16140.1 - 5.5 7.4 8.8 12 6.3 1.1 2.8 2 1 0 2 2 2 0 SlyX SYCE1 PF15233.1 KOS16140.1 - 5.5 6.9 10.4 5.8 6.8 1.0 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 TEA PF01285.13 KOS16141.1 - 4.3e-34 118.4 0.1 4.3e-34 118.4 0.1 2.2 3 0 0 3 3 3 1 TEA/ATTS domain family He_PIG PF05345.7 KOS16142.1 - 0.0085 16.0 1.7 0.022 14.7 0.1 2.3 2 0 0 2 2 2 1 Putative Ig domain Aa_trans PF01490.13 KOS16143.1 - 4.3e-64 216.4 32.5 5.1e-64 216.2 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KOS16143.1 - 0.00082 18.2 20.6 0.00082 18.2 14.3 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.20 KOS16145.1 - 3.8e-12 46.4 1.2 1.4e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KOS16145.1 - 1.6e-06 27.9 1.1 0.00034 20.3 0.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 KOS16145.1 - 0.00028 20.9 0.4 0.19 11.7 0.0 2.5 1 1 1 2 2 2 2 NADH(P)-binding adh_short_C2 PF13561.1 KOS16145.1 - 0.00064 19.5 0.3 0.0051 16.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Rad1 PF02144.11 KOS16146.1 - 1.4e-59 201.0 0.2 1.6e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 HLH PF00010.21 KOS16148.1 - 1.6e-13 50.0 0.1 3.1e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Methyltransf_16 PF10294.4 KOS16149.1 - 1.1e-15 57.4 0.0 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KOS16149.1 - 0.00037 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KOS16149.1 - 0.00061 19.4 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16149.1 - 0.0049 17.4 0.1 0.016 15.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS16149.1 - 0.047 13.7 0.1 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain RRP7 PF12923.2 KOS16150.1 - 2e-24 86.1 12.8 1.7e-22 79.8 3.4 2.6 3 0 0 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KOS16150.1 - 8.6e-05 22.0 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16150.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.12 KOS16150.1 - 0.065 13.5 3.1 2.3 8.6 2.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L14 DUF159 PF02586.9 KOS16151.1 - 1.5e-39 135.6 0.0 2.2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Methyltransf_16 PF10294.4 KOS16152.1 - 5.3e-11 42.2 0.0 9.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KOS16152.1 - 0.00018 22.0 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16152.1 - 0.00096 19.5 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KOS16152.1 - 0.001 18.5 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KOS16152.1 - 0.0064 16.2 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS16152.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KOS16152.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KOS16152.1 - 0.018 15.0 0.4 0.03 14.3 0.3 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 KOS16152.1 - 0.094 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 HSCB_C PF07743.8 KOS16153.1 - 8.8e-17 61.3 3.2 8.8e-17 61.3 2.2 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KOS16153.1 - 3e-10 39.6 0.0 9.9e-10 38.0 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 KOS16153.1 - 0.021 14.6 1.2 0.038 13.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-tcix PF14952.1 KOS16153.1 - 0.038 13.3 4.8 0.069 12.4 3.3 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.1 KOS16153.1 - 0.15 11.3 2.2 0.24 10.6 1.5 1.3 1 0 0 1 1 1 0 zinc-ribbon domain FdhE PF04216.7 KOS16153.1 - 2.6 7.6 6.1 13 5.3 0.4 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Ribosomal_L3 PF00297.17 KOS16155.1 - 1.9e-121 404.4 6.9 2.3e-121 404.2 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.20 KOS16156.1 - 2.4e-41 141.5 0.4 2.3e-24 85.9 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16156.1 - 7.1e-12 44.9 0.4 1.7e-09 37.1 0.1 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KOS16156.1 - 0.17 10.6 0.1 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sugar_tr PF00083.19 KOS16157.1 - 2.9e-118 395.3 26.5 3.3e-118 395.1 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KOS16157.1 - 3.7e-21 75.2 36.0 1.2e-15 57.1 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_N PF00033.14 KOS16157.1 - 0.0041 16.5 0.6 0.0041 16.5 0.4 2.9 4 0 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB MFS_3 PF05977.8 KOS16157.1 - 0.028 12.5 7.3 0.004 15.3 1.5 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector DUF554 PF04474.7 KOS16157.1 - 0.069 12.2 4.2 0.026 13.6 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF554) DUF2530 PF10745.4 KOS16157.1 - 7 6.7 10.4 3.1 7.8 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Sec15 PF04091.7 KOS16158.1 - 3.8e-82 276.0 0.2 3.8e-82 276.0 0.2 3.3 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 KOS16158.1 - 3.9e-09 36.4 3.5 1.2e-08 34.9 2.4 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 KOS16158.1 - 4.2e-07 29.6 8.9 4.2e-07 29.6 6.2 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps51 PF08700.6 KOS16158.1 - 8.4e-05 22.3 0.7 0.00037 20.2 0.5 2.2 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KOS16158.1 - 0.00072 19.4 7.1 0.00072 19.4 4.9 3.2 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 KOS16158.1 - 0.0028 17.6 6.0 0.0084 16.0 2.0 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps53_N PF04100.7 KOS16158.1 - 0.5 9.0 17.2 0.088 11.5 5.4 2.5 3 0 0 3 3 3 0 Vps53-like, N-terminal HA2 PF04408.18 KOS16159.1 - 9.7e-17 60.8 0.1 2.7e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KOS16159.1 - 1e-11 44.5 0.1 2.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 KOS16159.1 - 3e-08 34.1 0.0 0.016 15.7 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 KOS16159.1 - 5.7e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KOS16159.1 - 1.5e-05 24.5 0.1 3.4e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase EB1 PF03271.12 KOS16160.1 - 1.5e-12 47.3 0.2 2.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KOS16160.1 - 1.2e-05 25.3 0.1 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain LIP PF03583.9 KOS16161.1 - 1e-66 225.1 0.0 1.4e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 KOS16161.1 - 8.4e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2450 PF10475.4 KOS16161.1 - 0.00021 20.3 0.1 0.0003 19.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Peptidase_S9 PF00326.16 KOS16161.1 - 0.0013 18.0 0.3 0.84 8.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KOS16161.1 - 0.0016 17.9 0.0 0.0041 16.5 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 KOS16161.1 - 0.013 14.9 0.0 0.053 12.9 0.0 1.8 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF1399 PF07173.7 KOS16163.1 - 5e-12 46.2 2.4 9e-07 29.2 0.0 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF1399) zinc_ribbon_5 PF13719.1 KOS16163.1 - 0.0061 16.1 0.3 0.029 13.9 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KOS16163.1 - 0.0063 16.1 0.3 0.025 14.2 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.4 KOS16163.1 - 2 8.2 9.3 0.17 11.6 1.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Aa_trans PF01490.13 KOS16164.1 - 8.8e-16 57.3 42.2 1e-15 57.1 29.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2207 PF09972.4 KOS16164.1 - 0.63 8.5 0.0 0.63 8.5 0.0 3.5 2 2 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF1752 PF08550.5 KOS16165.1 - 1.9e-10 40.1 3.4 3.4e-10 39.3 2.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) LIP PF03583.9 KOS16166.1 - 4.9e-66 222.8 0.1 6.4e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KOS16166.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS16166.1 - 0.0031 17.2 0.0 0.0073 16.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KOS16166.1 - 0.0047 16.1 0.1 2.2 7.4 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KOS16166.1 - 0.016 14.6 0.1 0.15 11.4 0.0 2.3 1 1 2 3 3 3 0 Phospholipase/Carboxylesterase Membr_traf_MHD PF10540.4 KOS16167.1 - 3.2e-19 69.0 1.6 1.4e-18 67.0 0.1 3.0 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KOS16167.1 - 1.9e-05 24.4 0.0 6.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 C2 domain WD40 PF00400.27 KOS16168.1 - 7.4e-10 38.3 0.1 0.0021 17.8 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 KOS16168.1 - 3.1e-08 33.1 0.4 6.7e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KOS16168.1 - 0.00026 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 KOS16168.1 - 0.11 12.1 8.6 0.23 11.1 0.5 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif SH3_9 PF14604.1 KOS16169.1 - 4e-32 109.5 4.0 7.9e-16 57.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KOS16169.1 - 4.7e-26 89.9 2.9 1.3e-12 46.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KOS16169.1 - 3.7e-15 55.1 0.3 1.8e-07 30.5 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KOS16169.1 - 2.5e-14 53.2 0.0 3.9e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2370 PF10176.4 KOS16170.1 - 1.1e-49 168.8 0.0 2.7e-49 167.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF3722 PF12519.3 KOS16171.1 - 2.1e-41 141.8 0.9 1e-39 136.3 0.6 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KOS16171.1 - 3.7e-06 26.4 0.1 1.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic porin Ribophorin_I PF04597.9 KOS16172.1 - 2.1e-93 313.2 0.0 2.4e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I RabGAP-TBC PF00566.13 KOS16173.1 - 2e-24 86.2 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Bromo_TP PF07524.8 KOS16174.1 - 8.5e-08 31.8 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KOS16174.1 - 0.013 15.6 0.7 0.032 14.3 0.3 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KOS16174.1 - 0.032 14.2 0.2 0.032 14.2 0.1 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.15 KOS16175.1 - 8.6e-29 100.0 0.0 1.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KOS16175.1 - 3.9e-11 42.9 0.3 3.9e-11 42.9 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KOS16175.1 - 1.9e-09 37.6 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RNA_pol_3_Rpc31 PF11705.3 KOS16175.1 - 0.024 14.5 16.2 0.1 12.5 11.2 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.6 KOS16175.1 - 5.6 6.4 12.3 14 5.1 8.5 1.7 1 0 0 1 1 1 0 PPP4R2 DnaJ PF00226.26 KOS16176.1 - 2.4e-27 94.4 3.5 3.7e-27 93.8 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS16176.1 - 5.2e-15 55.1 0.3 5.3e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain RPT PF13446.1 KOS16176.1 - 0.082 12.3 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 A repeated domain in UCH-protein DUF1212 PF06738.7 KOS16177.1 - 1.9e-39 135.1 1.4 1.9e-39 135.1 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KOS16177.1 - 9.3e-13 48.2 4.9 9.3e-13 48.2 3.4 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3815) DUF46 PF01864.12 KOS16177.1 - 0.0092 15.8 1.5 0.018 14.8 1.1 1.4 1 0 0 1 1 1 1 Putative integral membrane protein DUF46 P22_AR_N PF10547.4 KOS16177.1 - 0.12 12.1 0.4 0.46 10.3 0.2 1.9 2 0 0 2 2 2 0 P22_AR N-terminal domain DnaJ PF00226.26 KOS16178.1 - 2.4e-16 59.2 1.3 4.9e-16 58.2 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Fer2_BFD PF04324.10 KOS16178.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain DUF4405 PF14358.1 KOS16178.1 - 0.48 10.5 4.1 1.4 9.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) MIS13 PF08202.6 KOS16179.1 - 9.8e-21 74.0 9.4 1e-18 67.4 6.5 2.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family RESP18 PF14948.1 KOS16179.1 - 0.042 13.8 2.0 0.2 11.7 1.4 2.2 1 1 0 1 1 1 0 RESP18 domain TMF_TATA_bd PF12325.3 KOS16179.1 - 0.39 10.4 7.8 0.15 11.7 2.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spt4 PF06093.8 KOS16180.1 - 1.2e-30 105.2 0.3 1.3e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNA_POL_M_15KD PF02150.11 KOS16180.1 - 0.052 13.2 0.6 8.8 6.1 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Cytochrom_c3_2 PF14537.1 KOS16180.1 - 0.061 13.6 0.5 0.076 13.3 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c3 Thioredoxin_2 PF13098.1 KOS16180.1 - 0.095 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain ABC_tran PF00005.22 KOS16181.1 - 7.3e-46 155.8 0.0 6.2e-26 91.3 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KOS16181.1 - 1.9e-17 64.1 0.0 0.01 15.7 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KOS16181.1 - 1e-09 37.9 0.1 0.0024 17.1 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 KOS16181.1 - 3.4e-08 33.0 0.1 7.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 KOS16181.1 - 1.3e-06 27.8 0.1 0.039 13.4 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KOS16181.1 - 6.9e-06 25.3 0.0 0.059 12.3 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 KOS16181.1 - 1.1e-05 25.9 4.3 0.024 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KOS16181.1 - 4.2e-05 23.4 0.0 0.013 15.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 KOS16181.1 - 0.00017 22.0 0.0 0.11 13.0 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein SbcCD_C PF13558.1 KOS16181.1 - 0.00024 20.9 0.0 0.33 10.8 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KOS16181.1 - 0.00025 21.8 0.0 0.13 13.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 KOS16181.1 - 0.00035 20.4 0.0 0.18 11.6 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 ArgK PF03308.11 KOS16181.1 - 0.00058 18.7 0.5 0.076 11.7 0.1 2.5 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KOS16181.1 - 0.00075 19.6 0.1 3.7 7.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KOS16181.1 - 0.0011 18.7 0.1 0.2 11.3 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B HEAT_EZ PF13513.1 KOS16181.1 - 0.0016 18.8 7.6 0.4 11.2 0.3 5.3 4 2 2 6 6 4 1 HEAT-like repeat AAA_25 PF13481.1 KOS16181.1 - 0.0017 17.7 0.0 1.9 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 KOS16181.1 - 0.0019 18.4 9.3 0.1 12.9 0.9 4.4 2 1 3 5 5 4 2 HEAT repeats DUF258 PF03193.11 KOS16181.1 - 0.0024 17.0 0.0 0.073 12.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KOS16181.1 - 0.0036 17.1 0.3 0.41 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS16181.1 - 0.0043 16.5 2.9 1.9 7.8 0.1 3.9 4 1 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 KOS16181.1 - 0.0043 16.1 0.0 6.5 5.7 0.0 3.5 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.7 KOS16181.1 - 0.0063 16.1 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Tudor-knot PF11717.3 KOS16181.1 - 0.0066 16.1 0.1 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Dynamin_N PF00350.18 KOS16181.1 - 0.024 14.4 0.1 0.3 10.8 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_28 PF13521.1 KOS16181.1 - 0.037 13.9 0.9 11 5.9 0.8 3.2 2 1 1 3 3 3 0 AAA domain CLASP_N PF12348.3 KOS16181.1 - 0.075 12.3 0.0 19 4.5 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal cobW PF02492.14 KOS16181.1 - 0.075 12.4 0.1 7.9 5.8 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KOS16181.1 - 0.077 13.1 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KOS16181.1 - 0.097 12.6 6.9 0.52 10.2 0.1 4.2 3 2 0 3 3 3 0 AAA ATPase domain ABC_ATPase PF09818.4 KOS16181.1 - 1.2 7.6 4.2 10 4.5 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class COX15-CtaA PF02628.10 KOS16182.1 - 1e-81 274.1 3.3 1.4e-81 273.6 2.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PepSY_TM_1 PF13172.1 KOS16182.1 - 0.52 10.1 9.2 1.8 8.4 0.1 3.7 3 0 0 3 3 3 0 PepSY-associated TM helix IMPDH PF00478.20 KOS16183.1 - 1.4e-138 461.6 0.0 4.7e-136 453.3 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KOS16183.1 - 2e-17 62.6 0.1 2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KOS16183.1 - 1.1e-13 51.0 4.7 2.5e-10 40.0 1.5 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KOS16183.1 - 3.9e-11 42.3 1.3 1.3e-10 40.6 0.7 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KOS16183.1 - 1.3e-07 31.1 1.3 9.2e-06 25.0 0.2 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KOS16183.1 - 0.00078 18.5 2.5 0.00089 18.3 0.8 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 KOS16183.1 - 0.0021 17.0 0.1 0.0049 15.8 0.1 1.6 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase EAL PF00563.15 KOS16183.1 - 0.027 13.9 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 EAL domain B12-binding PF02310.14 KOS16183.1 - 0.028 14.2 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DHO_dh PF01180.16 KOS16183.1 - 0.032 13.2 2.8 0.11 11.4 0.2 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PK PF00224.16 KOS16183.1 - 0.052 12.1 0.6 0.12 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain PcrB PF01884.12 KOS16183.1 - 0.053 12.7 3.2 1.4 8.1 0.0 3.5 4 0 0 4 4 4 0 PcrB family DUF1273 PF06908.6 KOS16183.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Dus PF01207.12 KOS16183.1 - 0.14 10.9 0.4 0.42 9.4 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Ank_2 PF12796.2 KOS16184.1 - 3.1e-22 78.7 0.4 2.9e-10 40.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS16184.1 - 5.4e-21 74.5 1.4 5.2e-12 45.9 0.1 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KOS16184.1 - 9.7e-20 69.3 0.3 8.6e-08 31.6 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KOS16184.1 - 1.8e-17 61.6 0.5 7e-05 22.6 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KOS16184.1 - 2.4e-17 62.5 0.6 3.3e-07 30.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KOS16184.1 - 3.7e-06 26.5 0.1 1.8e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain TarH PF02203.10 KOS16184.1 - 0.015 15.1 3.1 0.032 14.0 2.1 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue Sec62 PF03839.11 KOS16185.1 - 3.4e-45 154.2 3.8 5e-45 153.6 2.6 1.3 1 1 0 1 1 1 1 Translocation protein Sec62 Mito_carr PF00153.22 KOS16186.1 - 2.8e-65 216.0 3.6 7.8e-22 76.8 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 KOS16187.1 - 1.4e-38 132.0 0.0 2.9e-38 131.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16187.1 - 3.7e-19 68.3 0.0 7e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KOS16187.1 - 1.2e-17 63.2 0.1 2.1e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KOS16187.1 - 0.00091 19.0 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_M24 PF00557.19 KOS16188.1 - 2.9e-52 177.2 0.0 4.5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KOS16188.1 - 2e-35 121.1 0.0 4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fumble PF03630.9 KOS16189.1 - 1.3e-111 372.7 0.0 5.6e-83 278.6 0.0 2.1 2 0 0 2 2 2 2 Fumble TMF_DNA_bd PF12329.3 KOS16189.1 - 0.09 12.5 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding StbA PF06406.6 KOS16189.1 - 0.2 10.5 0.2 6.7 5.5 0.0 2.1 2 0 0 2 2 2 0 StbA protein SPX PF03105.14 KOS16190.1 - 5.7e-45 154.2 0.0 7.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KOS16190.1 - 5.7e-32 111.1 40.5 7.7e-32 110.7 28.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KOS16190.1 - 6.9e-18 64.3 36.6 5e-14 51.6 9.0 2.2 1 1 1 2 2 2 2 Citrate transporter DUF2421 PF10334.4 KOS16190.1 - 0.25 10.9 2.0 9 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) Methyltransf_28 PF02636.12 KOS16191.1 - 1.6e-34 119.4 0.0 3.6e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 KOS16191.1 - 0.00016 22.1 0.0 0.0018 18.6 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain RrnaAD PF00398.15 KOS16191.1 - 0.0057 15.7 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KOS16191.1 - 0.0096 15.9 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RNA_POL_M_15KD PF02150.11 KOS16192.1 - 1.9e-13 49.8 2.1 1.9e-13 49.8 1.4 2.5 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KOS16192.1 - 3.5e-10 39.3 2.8 3.5e-10 39.3 2.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 KOS16192.1 - 0.0055 16.9 1.7 2 8.7 0.2 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 KOS16192.1 - 0.018 15.3 1.0 0.018 15.3 0.7 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar GFA PF04828.9 KOS16192.1 - 0.018 14.9 3.3 0.53 10.2 0.2 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Pox_E10 PF04805.7 KOS16192.1 - 0.022 14.2 0.6 0.054 13.0 0.4 1.6 1 0 0 1 1 1 0 E10-like protein conserved region DZR PF12773.2 KOS16192.1 - 0.028 14.2 6.9 0.89 9.4 0.2 2.9 3 0 0 3 3 3 0 Double zinc ribbon T4_baseplate PF12322.3 KOS16192.1 - 0.038 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-ribbon_3 PF13248.1 KOS16192.1 - 0.045 12.9 0.1 0.045 12.9 0.1 3.1 3 1 0 3 3 2 0 zinc-ribbon domain CpXC PF14353.1 KOS16192.1 - 0.16 11.8 8.7 0.99 9.3 0.0 3.2 1 1 2 3 3 3 0 CpXC protein C1_1 PF00130.17 KOS16192.1 - 0.17 11.6 4.4 0.79 9.5 0.1 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.1 KOS16192.1 - 0.35 11.3 6.9 2.4 8.7 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.8 KOS16192.1 - 0.38 10.4 6.8 7.8 6.2 2.2 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_ME53 PF06061.6 KOS16192.1 - 0.48 9.3 7.1 0.076 11.9 1.4 1.8 2 0 0 2 2 2 0 Baculoviridae ME53 zinc_ribbon_4 PF13717.1 KOS16192.1 - 0.58 9.9 0.2 0.58 9.9 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KOS16192.1 - 0.7 9.5 0.2 0.7 9.5 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain RecR PF02132.10 KOS16192.1 - 1.4 8.3 0.1 1.4 8.3 0.1 3.2 4 0 0 4 4 4 0 RecR protein DNA_RNApol_7kD PF03604.8 KOS16192.1 - 1.6 8.2 11.7 2.3 7.7 0.0 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Cys_rich_CPXG PF14255.1 KOS16192.1 - 2.2 8.1 0.0 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.5 KOS16192.1 - 2.5 8.1 12.5 3.7 7.5 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KOS16192.1 - 3.7 7.4 12.9 4.9 7.0 3.5 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 KOS16192.1 - 4.9 7.6 8.5 62 4.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.6 KOS16192.1 - 5.4 6.7 8.2 16 5.2 0.2 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Cpn60_TCP1 PF00118.19 KOS16193.1 - 5.9e-137 457.2 8.8 7e-137 456.9 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAGLU_C PF12972.2 KOS16193.1 - 0.11 11.8 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Laminin_G_3 PF13385.1 KOS16194.1 - 2.3e-16 60.4 2.7 2.3e-16 60.4 1.9 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KOS16194.1 - 0.0026 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain CAF1A PF12253.3 KOS16196.1 - 9.9e-22 76.8 5.7 9.9e-22 76.8 3.9 2.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A ORC3_N PF07034.6 KOS16197.1 - 1.9e-05 23.8 0.6 0.091 11.7 0.0 2.9 2 1 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus WD40 PF00400.27 KOS16198.1 - 2.7e-22 77.7 4.4 0.00055 19.7 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat VID27 PF08553.5 KOS16198.1 - 0.0071 14.6 0.0 0.012 13.8 0.0 1.3 1 0 0 1 1 1 1 VID27 cytoplasmic protein NPR2 PF06218.6 KOS16199.1 - 2.9e-101 339.2 0.2 5.4e-44 150.5 0.2 3.2 2 1 1 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.8 KOS16199.1 - 6.8e-06 24.8 0.1 6.8e-06 24.8 0.1 2.4 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 SNF2_N PF00176.18 KOS16201.1 - 9.9e-73 244.5 0.0 1.4e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KOS16201.1 - 3.3e-19 68.7 0.0 6.2e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KOS16201.1 - 1.9e-15 56.4 0.0 4.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS16201.1 - 5.4e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 KOS16201.1 - 0.0007 19.2 13.1 0.0014 18.2 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KOS16201.1 - 0.0073 16.3 16.5 0.017 15.1 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IFRD_C PF04836.7 KOS16201.1 - 0.016 15.3 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Interferon-related protein conserved region zf-RING_2 PF13639.1 KOS16201.1 - 0.029 14.2 16.2 0.067 13.0 11.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KOS16201.1 - 0.45 10.2 17.8 0.25 11.0 10.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rhodanese PF00581.15 KOS16202.1 - 3e-11 43.6 0.0 6.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Sec7 PF01369.15 KOS16203.1 - 4.3e-59 199.3 0.0 7.1e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KOS16203.1 - 2.2e-14 53.2 0.0 9.7e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF515 PF04415.7 KOS16203.1 - 0.73 8.0 0.6 1.1 7.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Prefoldin_2 PF01920.15 KOS16204.1 - 1.7e-12 46.9 6.4 2e-12 46.8 4.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF705 PF05152.7 KOS16204.1 - 0.022 13.7 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Stk19 PF10494.4 KOS16204.1 - 0.04 13.3 0.8 0.045 13.1 0.6 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 Mod_r PF07200.8 KOS16204.1 - 0.047 13.6 2.8 0.048 13.5 1.0 1.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF87 PF01935.12 KOS16204.1 - 0.13 12.0 1.3 0.15 11.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF4441 PF14536.1 KOS16204.1 - 0.52 10.2 2.3 8.6 6.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) Cortex-I_coil PF09304.5 KOS16204.1 - 0.73 9.9 7.4 0.62 10.1 1.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil MscS_porin PF12795.2 KOS16204.1 - 0.93 8.7 6.2 6.4 6.0 0.3 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Synaptobrevin PF00957.16 KOS16204.1 - 1.1 8.8 5.8 1 8.9 0.4 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF4200 PF13863.1 KOS16204.1 - 1.4 8.8 10.6 9.2 6.2 7.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Ada3 PF10198.4 KOS16204.1 - 8.2 6.1 8.1 39 3.9 5.6 1.9 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Ribonuc_P_40 PF08584.6 KOS16205.1 - 3.6e-17 62.2 0.0 1.7e-14 53.4 0.0 2.0 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit DUF3433 PF11915.3 KOS16205.1 - 0.082 13.0 1.3 0.27 11.4 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3433) Sec66 PF09802.4 KOS16206.1 - 5.1e-31 107.5 0.7 6.1e-31 107.2 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF964 PF06133.6 KOS16206.1 - 0.018 15.0 1.0 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF964) ATP_transf PF09830.4 KOS16207.1 - 5.6e-14 51.6 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 KOS16207.1 - 0.0014 19.0 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 HIT domain IFRD PF05004.8 KOS16207.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) E1-E2_ATPase PF00122.15 KOS16208.1 - 9.8e-66 221.0 1.2 9.8e-66 221.0 0.9 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KOS16208.1 - 1.3e-23 84.5 0.1 3.2e-23 83.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KOS16208.1 - 6.4e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KOS16208.1 - 4.5e-10 38.8 0.0 9.9e-10 37.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KOS16208.1 - 0.0005 19.7 0.1 0.0018 17.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KOS16208.1 - 0.0022 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit NDUF_B4 PF07225.7 KOS16208.1 - 0.25 11.1 1.4 0.36 10.6 0.2 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Cpn60_TCP1 PF00118.19 KOS16209.1 - 1.3e-156 522.0 2.0 1.4e-156 521.8 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L11_N PF03946.9 KOS16210.1 - 4.9e-16 57.9 0.0 8.3e-16 57.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KOS16210.1 - 4.7e-11 42.6 0.0 7.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DEAD PF00270.24 KOS16211.1 - 2.6e-41 140.9 0.1 4e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16211.1 - 1.1e-23 82.9 0.1 1.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KOS16211.1 - 0.0071 15.4 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ala_racemase_N PF01168.15 KOS16211.1 - 0.1 12.1 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain Chitin_synth_2 PF03142.10 KOS16212.1 - 2.4e-273 907.3 0.3 3e-273 907.0 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 KOS16212.1 - 8.7e-15 55.1 0.1 1.7e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KOS16212.1 - 2.5e-14 53.4 1.3 2.5e-14 53.4 0.9 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KOS16212.1 - 7.3e-06 25.3 0.0 9.1e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KOS16212.1 - 0.0028 17.3 0.0 0.0083 15.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 RRM_1 PF00076.17 KOS16213.1 - 3.6e-23 80.9 0.0 4.9e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16213.1 - 2.2e-19 69.1 0.0 3.4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16213.1 - 2.1e-11 43.5 0.0 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_5 PF12695.2 KOS16214.1 - 0.00033 20.4 0.0 0.00055 19.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KOS16214.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 KOS16214.1 - 0.024 14.5 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Herpes_gE PF02480.11 KOS16214.1 - 0.039 12.2 0.0 0.054 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Chlorophyllase2 PF12740.2 KOS16214.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PPR_2 PF13041.1 KOS16215.1 - 3.3e-09 36.5 0.0 5.4e-06 26.2 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KOS16215.1 - 7.5e-05 22.7 3.5 0.0059 16.7 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 KOS16215.1 - 0.00053 19.7 0.5 3.1 7.9 0.0 4.2 5 0 0 5 5 5 2 PPR repeat GLE1 PF07817.8 KOS16216.1 - 1.9e-54 184.3 0.5 3.2e-54 183.5 0.0 1.6 2 0 0 2 2 2 1 GLE1-like protein PA26 PF04636.8 KOS16216.1 - 0.11 11.1 1.4 0.15 10.7 1.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Peptidase_S15 PF02129.13 KOS16216.1 - 0.89 8.9 5.2 1.5 8.1 3.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Spore_coat_CotO PF14153.1 KOS16216.1 - 1.3 8.4 13.0 2.3 7.6 9.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO AIF-MLS PF14962.1 KOS16216.1 - 2.5 7.7 15.5 4.7 6.8 10.8 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MCPVI PF02993.9 KOS16216.1 - 5.5 7.0 10.4 10 6.1 7.2 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Kelch_3 PF13415.1 KOS16217.1 - 4.6e-28 96.7 4.3 3.8e-05 23.7 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KOS16217.1 - 3.3e-26 90.7 8.6 0.0003 20.5 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.1 KOS16217.1 - 9.6e-24 83.0 0.4 9.6e-24 83.0 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KOS16217.1 - 4.6e-17 61.3 6.5 0.00039 20.4 0.0 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KOS16217.1 - 7.6e-15 54.4 4.3 0.0008 19.2 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KOS16217.1 - 1.4e-10 40.4 5.1 0.0036 16.8 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KOS16217.1 - 2.4e-10 39.7 2.5 0.00096 18.8 0.0 5.7 5 0 0 5 5 5 2 Kelch motif FoP_duplication PF13865.1 KOS16217.1 - 0.83 10.1 9.5 0.13 12.7 3.1 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Nop25 PF09805.4 KOS16217.1 - 1.7 8.7 14.0 1.5 8.8 6.2 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Pectate_lyase_3 PF12708.2 KOS16218.1 - 2.9e-74 249.9 1.3 3.7e-58 197.2 0.1 2.2 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KOS16218.1 - 1.9e-05 24.0 2.7 0.085 12.3 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KOS16218.1 - 0.0017 18.0 0.0 0.008 15.9 0.0 2.0 1 1 0 1 1 1 1 Right handed beta helix region RNase_H PF00075.19 KOS16219.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 RNase H Dsl1_C PF11989.3 KOS16220.1 - 1.2e-06 27.8 0.0 1.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.8 KOS16220.1 - 0.0031 15.7 14.0 0.0068 14.6 9.7 1.7 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Nup96 PF12110.3 KOS16221.1 - 5.9e-84 281.6 2.9 8.7e-84 281.0 2.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KOS16221.1 - 1.3e-39 135.2 0.0 2.7e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KOS16221.1 - 1.2e-21 77.1 383.0 3.6e-07 30.4 34.4 10.7 4 2 7 11 11 11 8 Nucleoporin FG repeat region ketoacyl-synt PF00109.21 KOS16222.1 - 2e-62 210.9 0.0 4e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 KOS16222.1 - 3.4e-48 163.7 0.0 7.5e-48 162.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 KOS16222.1 - 8e-48 163.4 0.4 1.4e-47 162.6 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KOS16222.1 - 1.2e-36 126.1 0.3 5.2e-33 114.2 0.0 3.1 2 1 0 2 2 2 2 KR domain adh_short PF00106.20 KOS16222.1 - 4.3e-34 117.8 0.8 8.8e-29 100.5 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KOS16222.1 - 1.2e-31 108.9 0.0 3.2e-31 107.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KOS16222.1 - 9.9e-27 93.8 0.0 1.8e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 KOS16222.1 - 5.9e-16 58.6 0.0 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KOS16222.1 - 4.4e-11 42.4 0.1 1.4e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KOS16222.1 - 1.1e-09 38.5 2.5 1.2e-07 31.8 1.2 3.8 4 1 0 4 4 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 KOS16222.1 - 1.3e-06 27.3 0.1 9.5e-06 24.5 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KOS16222.1 - 3.7e-05 22.7 0.1 3.7e-05 22.7 0.1 2.0 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein ADH_zinc_N_2 PF13602.1 KOS16222.1 - 0.00017 22.4 0.6 0.0029 18.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KOS16222.1 - 0.00019 21.6 0.6 0.00049 20.3 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KOS16222.1 - 0.00041 20.0 0.1 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 KOS16222.1 - 0.00074 19.9 0.0 0.0031 17.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS16222.1 - 0.0021 18.5 0.0 0.0082 16.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain DapB_N PF01113.15 KOS16222.1 - 0.0037 17.1 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KOS16222.1 - 0.007 15.6 0.1 0.022 14.0 0.1 1.8 2 0 0 2 2 1 1 NmrA-like family Methyltransf_31 PF13847.1 KOS16222.1 - 0.0078 15.8 0.0 0.064 12.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ThiF PF00899.16 KOS16222.1 - 0.11 12.3 0.2 0.39 10.5 0.2 2.0 1 0 0 1 1 1 0 ThiF family Methyltransf_23 PF13489.1 KOS16222.1 - 0.13 11.9 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PTH2 PF01981.11 KOS16223.1 - 3.4e-06 26.7 0.1 5e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RhoGEF PF00621.15 KOS16224.1 - 8.8e-42 143.0 0.6 3.9e-39 134.3 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain FYVE PF01363.16 KOS16224.1 - 5.6e-17 61.4 12.3 1.2e-16 60.3 8.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KOS16224.1 - 1.1e-07 32.0 0.1 8.9e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_5 PF15405.1 KOS16224.1 - 0.11 12.4 0.1 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.1 KOS16224.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Rft-1 PF04506.8 KOS16225.1 - 1.7e-60 204.9 4.5 8.6e-59 199.3 3.1 2.4 1 1 0 1 1 1 1 Rft protein LIP PF03583.9 KOS16226.1 - 4.8e-12 45.6 0.0 5.5e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase SRP9-21 PF05486.7 KOS16227.1 - 3.6e-14 52.2 0.4 5e-14 51.8 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) SRP-alpha_N PF04086.8 KOS16228.1 - 0.0071 15.7 1.8 0.0089 15.4 1.2 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Abhydrolase_8 PF06259.7 KOS16228.1 - 1.6 8.1 8.2 0.22 11.0 2.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase Glyoxalase_2 PF12681.2 KOS16229.1 - 3.6e-13 50.0 0.0 8e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KOS16229.1 - 2.3e-05 24.3 0.0 0.00065 19.6 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1620 PF07774.8 KOS16230.1 - 2.8e-46 157.5 0.0 3.8e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KOS16230.1 - 0.00023 20.7 0.2 0.0012 18.3 0.1 2.3 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KOS16230.1 - 0.0049 16.3 3.9 0.4 10.3 0.0 4.4 5 0 0 5 5 5 1 PQQ enzyme repeat Mus7 PF09462.5 KOS16231.1 - 9.1e-89 298.9 4.3 1.4e-88 298.3 3.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family B-block_TFIIIC PF04182.7 KOS16232.1 - 4.1e-11 42.5 0.0 1.3e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KOS16232.1 - 0.00047 19.7 4.1 0.058 13.0 0.0 5.1 5 0 0 5 5 5 1 MarR family HTH_20 PF12840.2 KOS16232.1 - 0.0021 17.8 2.2 3.5 7.5 0.2 4.1 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_24 PF13412.1 KOS16232.1 - 0.08 12.3 0.0 23 4.4 0.0 3.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding OPA3 PF07047.7 KOS16234.1 - 3.6e-32 110.9 0.8 5.7e-32 110.3 0.6 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Arc_PepC PF06819.6 KOS16235.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain ATG16 PF08614.6 KOS16235.1 - 0.024 14.4 1.5 0.036 13.9 1.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 KOS16235.1 - 0.027 14.4 1.0 0.027 14.4 0.7 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.16 KOS16235.1 - 0.051 13.5 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 bZIP transcription factor CNTF PF01110.12 KOS16235.1 - 0.062 12.5 0.1 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Ciliary neurotrophic factor FliJ PF02050.11 KOS16235.1 - 0.063 13.3 1.7 0.12 12.4 1.2 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein HD_5 PF13487.1 KOS16235.1 - 0.079 12.9 0.2 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 HD domain AAA_13 PF13166.1 KOS16235.1 - 0.086 11.2 1.4 0.1 11.0 1.0 1.0 1 0 0 1 1 1 0 AAA domain Hemerythrin PF01814.18 KOS16235.1 - 0.17 12.0 3.9 0.26 11.4 2.7 1.4 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DivIC PF04977.10 KOS16235.1 - 1.2 8.6 5.9 0.62 9.5 0.8 2.6 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.10 KOS16235.1 - 4.5 7.1 7.2 0.44 10.4 0.9 2.3 3 0 0 3 3 3 0 Basic region leucine zipper IncA PF04156.9 KOS16235.1 - 4.9 6.6 9.3 13 5.2 6.4 1.7 1 1 0 1 1 1 0 IncA protein WD40 PF00400.27 KOS16236.1 - 6.9e-38 127.1 14.6 1.1e-10 41.0 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 KOS16236.1 - 9.7e-06 25.1 0.1 0.0091 15.6 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 KOS16236.1 - 0.0022 17.7 1.0 0.29 10.8 0.0 3.5 3 1 1 4 4 4 1 Transcription factor IIIC subunit delta N-term eIF2A PF08662.6 KOS16236.1 - 0.004 16.8 0.0 2 8.0 0.0 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KOS16236.1 - 0.01 15.2 0.7 0.021 14.2 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KOS16236.1 - 0.069 11.2 0.0 0.31 9.1 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DDOST_48kD PF03345.9 KOS16237.1 - 9.7e-98 327.4 0.0 1.7e-97 326.6 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.4 KOS16237.1 - 0.034 12.2 0.0 0.048 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF410 PF04190.8 KOS16238.1 - 2.4e-22 79.7 0.5 1.7e-21 76.9 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF410) LRR_6 PF13516.1 KOS16239.1 - 4.6e-07 29.2 0.0 9.5 6.6 0.0 7.0 7 0 0 7 7 7 3 Leucine Rich repeat Arrestin_N PF00339.24 KOS16240.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Lipase_3 PF01764.20 KOS16241.1 - 4.2e-22 78.2 0.0 5.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KOS16241.1 - 0.00029 20.7 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS16241.1 - 0.004 16.7 0.0 0.0092 15.5 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS16241.1 - 0.013 15.2 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 KOS16241.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 KOS16242.1 - 6.8e-18 64.6 0.0 8.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KOS16242.1 - 8.6e-05 22.5 0.0 9.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS16242.1 - 0.0072 16.0 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KOS16242.1 - 0.0094 14.4 0.1 0.014 13.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KOS16242.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KOS16242.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KOS16242.1 - 0.034 13.5 0.0 0.046 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 KOS16242.1 - 0.075 12.6 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3546 PF12066.3 KOS16243.1 - 3.3e-16 59.2 1.1 8.9e-16 57.8 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KOS16243.1 - 1.7e-06 28.4 0.0 2.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Arsenite-resistance protein 2 RRM_1 PF00076.17 KOS16243.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 KOS16243.1 - 0.13 11.8 3.0 0.36 10.4 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) PPR_2 PF13041.1 KOS16245.1 - 5.8e-36 122.2 0.0 1e-11 44.6 0.0 10.3 10 1 1 11 11 11 5 PPR repeat family PPR_3 PF13812.1 KOS16245.1 - 9e-29 97.3 18.8 2.9e-05 24.0 0.0 13.1 14 0 0 14 14 14 6 Pentatricopeptide repeat domain PPR PF01535.15 KOS16245.1 - 3.2e-28 95.7 1.8 2.2e-05 24.1 0.0 13.2 12 2 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 KOS16245.1 - 1.3e-13 50.1 3.7 8.8e-07 28.2 0.0 8.6 11 2 0 11 11 11 1 PPR repeat ECSIT PF06239.6 KOS16245.1 - 0.00064 18.6 0.0 0.035 12.9 0.0 3.2 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 KOS16245.1 - 0.0054 17.2 24.9 0.3 11.8 0.7 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat RPM2 PF08579.6 KOS16245.1 - 0.28 11.3 0.0 9.1 6.4 0.0 3.1 3 1 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Acetyltransf_1 PF00583.19 KOS16246.1 - 1.5e-16 60.1 0.1 2.5e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS16246.1 - 1.6e-09 37.9 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS16246.1 - 6.4e-09 35.4 0.1 9.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KOS16246.1 - 6.3e-08 32.8 0.0 8.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS16246.1 - 1.8e-07 31.2 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS16246.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS16246.1 - 1.7e-06 27.9 0.1 3e-06 27.0 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KOS16246.1 - 0.00026 20.8 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KOS16246.1 - 0.091 12.3 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PMI_typeI PF01238.16 KOS16247.1 - 1.6e-104 349.8 0.0 2.1e-104 349.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_N PF06719.8 KOS16247.1 - 0.002 17.4 0.0 0.0047 16.2 0.0 1.6 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus Cupin_2 PF07883.6 KOS16247.1 - 0.0039 16.6 0.5 0.12 11.8 0.1 2.3 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KOS16247.1 - 0.25 11.0 1.2 2.4 7.8 0.0 2.6 3 0 0 3 3 3 0 AraC-like ligand binding domain NDUF_B7 PF05676.8 KOS16248.1 - 2.1e-17 62.2 0.1 2.6e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KOS16248.1 - 0.029 14.1 0.4 0.042 13.6 0.3 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like RNA_pol_A_bac PF01000.21 KOS16249.1 - 9.6e-30 103.0 0.0 1.8e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KOS16249.1 - 1.4e-13 49.7 0.0 1.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DSPn PF14671.1 KOS16250.1 - 3.4e-36 124.3 0.0 3.2e-35 121.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KOS16250.1 - 2.5e-15 56.2 0.2 8.2e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KOS16250.1 - 5.5e-05 22.6 0.0 8.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KOS16250.1 - 0.0042 17.1 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KOS16250.1 - 0.038 14.2 0.1 0.077 13.2 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family XRN_N PF03159.13 KOS16251.1 - 8.9e-108 359.1 0.0 2.1e-107 357.9 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Pentapeptide_2 PF01469.13 KOS16251.1 - 0.0003 20.3 0.8 0.00053 19.5 0.6 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) zf-CCHC PF00098.18 KOS16251.1 - 0.0011 18.8 7.3 0.0026 17.5 5.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Astro_capsid PF03115.9 KOS16251.1 - 8.6 4.4 6.3 15 3.6 4.4 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PUF PF00806.14 KOS16252.1 - 8.2e-23 78.5 0.0 0.0017 17.7 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KOS16252.1 - 3.4e-16 58.6 0.0 1.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16252.1 - 2.3e-14 53.0 0.0 8.6e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16252.1 - 1.2e-08 34.6 0.0 0.00018 21.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.17 KOS16253.1 - 1.4e-40 138.0 0.1 2.9e-40 137.0 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 KOS16253.1 - 2.1e-13 49.5 0.2 3.7e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 KOS16253.1 - 4.1e-11 42.8 7.9 1.2e-10 41.3 5.5 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KOS16253.1 - 7.4e-11 42.0 7.3 2.2e-10 40.5 5.0 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain Peptidase_M28 PF04389.12 KOS16254.1 - 5.6e-34 117.4 0.0 7.7e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 AAA PF00004.24 KOS16255.1 - 3.9e-16 59.4 0.0 6.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KOS16255.1 - 1.8e-13 50.5 0.0 2e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Ribosomal_S6 PF01250.12 KOS16255.1 - 6.4e-09 35.5 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S6 Rad17 PF03215.10 KOS16255.1 - 4.5e-07 28.9 0.0 6.2e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KOS16255.1 - 1.4e-06 28.4 0.0 6.6e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS16255.1 - 3.6e-06 26.6 0.2 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KOS16255.1 - 4.9e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.6 KOS16255.1 - 9.8e-06 25.4 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_11 PF13086.1 KOS16255.1 - 1.8e-05 24.4 0.0 4.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KOS16255.1 - 1.8e-05 24.8 0.1 0.00027 20.9 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KOS16255.1 - 2.2e-05 23.6 0.0 4.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KOS16255.1 - 0.00019 20.6 0.0 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KOS16255.1 - 0.00072 19.3 0.0 0.0035 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KOS16255.1 - 0.0017 17.8 0.3 0.38 10.2 0.0 2.4 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 KOS16255.1 - 0.0018 17.8 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KOS16255.1 - 0.0038 16.8 0.1 0.0084 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KOS16255.1 - 0.0085 15.0 0.0 0.031 13.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 KOS16255.1 - 0.014 14.2 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KOS16255.1 - 0.015 14.6 0.2 0.066 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 KOS16255.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KOS16255.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KOS16255.1 - 0.027 13.9 0.0 0.32 10.4 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KOS16255.1 - 0.038 14.7 0.0 0.088 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KOS16255.1 - 0.055 12.9 0.1 0.86 9.0 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 KOS16255.1 - 0.059 12.5 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 KOS16255.1 - 0.066 12.8 0.0 0.35 10.4 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 KOS16255.1 - 0.096 11.4 0.1 0.45 9.2 0.1 1.9 1 1 0 1 1 1 0 MCM2/3/5 family AAA_18 PF13238.1 KOS16255.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NIF PF03031.13 KOS16256.1 - 1.2e-24 86.7 0.0 9e-24 83.9 0.0 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KOS16256.1 - 2.9e-10 39.8 0.0 6.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KOS16256.1 - 2.9e-07 30.5 0.0 6.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Noelin-1 PF12308.3 KOS16256.1 - 0.12 12.2 2.2 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Neurogenesis glycoprotein MFS_1 PF07690.11 KOS16257.1 - 2.2e-36 125.3 27.6 2.2e-36 125.3 19.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3596 PF12167.3 KOS16257.1 - 0.081 12.4 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) Ribosomal_L2_C PF03947.13 KOS16258.1 - 1e-41 141.7 1.9 1.4e-41 141.2 1.3 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KOS16258.1 - 8.1e-14 51.3 0.0 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PTPLA PF04387.9 KOS16259.1 - 6.9e-46 155.6 8.7 6.9e-46 155.6 6.0 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA CDP-OH_P_transf PF01066.16 KOS16260.1 - 1.8e-17 63.5 10.8 6.2e-17 61.7 7.5 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Ras PF00071.17 KOS16261.1 - 8.5e-66 220.3 0.7 1.1e-65 219.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KOS16261.1 - 1.2e-21 77.4 0.4 3.2e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KOS16261.1 - 3.2e-17 62.3 0.1 4e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KOS16261.1 - 1.9e-06 27.2 0.0 2.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS16261.1 - 2.7e-06 26.9 0.1 6.1e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KOS16261.1 - 3.9e-05 22.9 0.1 4.9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KOS16261.1 - 4.5e-05 23.3 1.2 5.4e-05 23.1 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KOS16261.1 - 0.00017 21.7 0.2 0.00029 20.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 KOS16261.1 - 0.00038 19.6 0.8 0.017 14.3 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KOS16261.1 - 0.0013 18.0 0.1 0.013 14.7 0.0 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 KOS16261.1 - 0.0014 18.0 0.3 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 KOS16261.1 - 0.0016 18.6 0.1 0.36 11.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS16261.1 - 0.006 16.3 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS16261.1 - 0.0063 16.8 0.9 0.18 12.1 0.6 2.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KOS16261.1 - 0.016 15.1 0.3 0.056 13.4 0.1 2.2 1 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KOS16261.1 - 0.051 13.0 0.1 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KOS16261.1 - 0.072 12.6 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KOS16261.1 - 0.077 11.9 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin UPF1_Zn_bind PF09416.5 KOS16262.1 - 5.2e-68 227.4 1.5 5.2e-68 227.4 1.0 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KOS16262.1 - 1.4e-59 200.8 0.0 2.6e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS16262.1 - 1.7e-52 178.3 2.7 2.6e-52 177.7 1.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS16262.1 - 3.3e-15 55.6 1.3 3.8e-13 48.9 0.3 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KOS16262.1 - 3e-14 53.0 0.6 2e-12 47.0 0.2 3.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 KOS16262.1 - 3.9e-07 30.0 0.1 2.3e-06 27.5 0.1 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KOS16262.1 - 6.2e-06 25.9 0.1 0.18 11.3 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KOS16262.1 - 1.9e-05 24.3 0.4 0.00011 21.8 0.0 2.4 2 1 0 2 2 2 1 Helicase DUF2075 PF09848.4 KOS16262.1 - 6e-05 22.1 4.1 0.00046 19.2 0.4 3.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KOS16262.1 - 9.9e-05 21.7 3.1 0.047 13.0 0.1 2.6 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 KOS16262.1 - 0.00068 19.1 0.2 0.024 14.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DEAD PF00270.24 KOS16262.1 - 0.00083 18.8 1.0 0.0026 17.2 0.5 2.0 2 1 1 3 3 3 1 DEAD/DEAH box helicase PhoH PF02562.11 KOS16262.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 KOS16262.1 - 0.022 14.4 0.2 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.9 KOS16262.1 - 0.029 13.3 0.0 5 5.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.24 KOS16262.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS16262.1 - 0.055 13.6 0.2 0.25 11.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 KOS16262.1 - 0.074 12.1 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 KOS16262.1 - 0.075 12.4 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS16262.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RRM_1 PF00076.17 KOS16263.1 - 3.8e-34 116.1 0.0 8.1e-19 67.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16263.1 - 1.2e-21 76.3 0.0 6.5e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16263.1 - 3.8e-18 65.0 0.0 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KOS16263.1 - 0.002 17.8 0.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Mito_carr PF00153.22 KOS16264.1 - 6.8e-05 22.4 1.0 0.0078 15.8 0.1 3.2 3 0 0 3 3 3 1 Mitochondrial carrier protein Ripply PF14998.1 KOS16264.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Transcription Regulator ABC_tran PF00005.22 KOS16265.1 - 3.5e-61 205.4 0.0 7.9e-30 103.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS16265.1 - 9.4e-50 169.5 31.2 9.2e-28 97.4 8.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KOS16265.1 - 2.5e-14 53.0 2.6 1.1e-07 31.3 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KOS16265.1 - 2.3e-11 44.2 0.0 0.14 12.0 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KOS16265.1 - 3.8e-08 34.1 0.0 0.0017 19.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS16265.1 - 6.5e-08 31.9 0.8 0.00052 19.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KOS16265.1 - 7.6e-07 28.4 0.0 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KOS16265.1 - 2.5e-06 27.9 0.2 0.00021 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KOS16265.1 - 7.1e-06 26.1 0.5 0.54 10.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KOS16265.1 - 7.2e-06 25.5 0.0 0.032 13.6 0.0 3.4 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KOS16265.1 - 1.2e-05 25.4 1.7 0.13 12.2 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KOS16265.1 - 1.2e-05 24.1 0.0 0.032 12.8 0.0 3.1 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 KOS16265.1 - 1.9e-05 24.9 0.0 0.063 13.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 KOS16265.1 - 0.00046 19.3 0.0 0.08 12.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KOS16265.1 - 0.0014 18.5 0.2 0.57 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KOS16265.1 - 0.0021 17.5 2.2 2.8 7.2 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 KOS16265.1 - 0.0023 17.8 0.0 1.9 8.4 0.0 3.3 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KOS16265.1 - 0.0057 16.3 0.1 1.3 8.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) MobB PF03205.9 KOS16265.1 - 0.0087 15.7 0.1 4.9 6.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KOS16265.1 - 0.022 14.7 0.1 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KOS16265.1 - 0.027 13.9 0.0 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KOS16265.1 - 0.031 14.4 0.2 25 5.0 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KOS16265.1 - 0.037 14.2 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 KOS16265.1 - 0.063 13.2 0.0 7 6.6 0.0 3.2 4 0 0 4 4 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KOS16265.1 - 0.084 12.6 0.4 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KOS16265.1 - 0.11 12.1 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.15 KOS16265.1 - 0.15 10.6 0.0 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit VirE PF05272.6 KOS16265.1 - 0.2 11.1 0.0 0.7 9.3 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E Pkinase PF00069.20 KOS16266.1 - 6.1e-43 146.8 0.0 9.1e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KOS16266.1 - 1.8e-42 144.2 0.3 2.8e-42 143.5 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KOS16266.1 - 1.1e-22 80.4 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KOS16266.1 - 0.0001 21.8 0.3 0.01 15.2 0.0 3.0 3 1 1 4 4 4 1 PQQ-like domain PQQ PF01011.16 KOS16266.1 - 0.0004 19.7 0.2 0.045 13.2 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat YrbL-PhoP_reg PF10707.4 KOS16266.1 - 0.046 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KOS16266.1 - 0.056 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SynMuv_product PF06047.6 KOS16267.1 - 1.3e-41 140.5 2.0 2.4e-41 139.7 1.4 1.4 1 0 0 1 1 1 1 Ras-induced vulval development antagonist Transformer PF06495.6 KOS16267.1 - 0.39 10.5 24.4 0.06 13.2 10.3 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein tRNA-synt_1c PF00749.16 KOS16268.1 - 8.4e-83 277.6 0.0 1.2e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ArsA_ATPase PF02374.10 KOS16269.1 - 3.3e-107 358.0 0.1 3.8e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KOS16269.1 - 2.2e-14 53.3 0.1 4.1e-14 52.4 0.1 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KOS16269.1 - 1.9e-09 37.6 0.0 4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KOS16269.1 - 1.5e-05 24.3 0.2 4.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KOS16269.1 - 0.00046 19.6 0.1 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 KOS16269.1 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 YhjQ protein PhoH PF02562.11 KOS16269.1 - 0.0023 17.1 0.0 0.0051 16.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 KOS16269.1 - 0.0038 16.9 0.1 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain MipZ PF09140.6 KOS16269.1 - 0.0097 15.0 0.1 0.016 14.2 0.1 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KOS16269.1 - 0.01 15.2 0.3 0.084 12.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KOS16269.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Tir_receptor_N PF07490.6 KOS16269.1 - 0.02 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus VirC1 PF07015.6 KOS16269.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein NB-ARC PF00931.17 KOS16269.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 KOS16269.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CTP_synth_N PF06418.9 KOS16269.1 - 0.13 11.3 0.1 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus DEAD PF00270.24 KOS16270.1 - 2.2e-41 141.1 0.0 1.7e-40 138.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16270.1 - 1.8e-23 82.1 0.1 4.4e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS16270.1 - 0.00036 20.4 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KOS16270.1 - 0.0045 16.9 0.1 0.073 13.0 0.0 2.5 2 0 0 2 2 2 1 Helicase C-terminal domain Helicase_C_4 PF13871.1 KOS16270.1 - 0.0067 15.8 0.2 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Helicase_C-like zf-CCHC_4 PF14392.1 KOS16270.1 - 0.023 14.3 0.3 0.052 13.2 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1253 PF06862.7 KOS16270.1 - 0.063 11.6 0.1 0.69 8.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) zf-CCHC PF00098.18 KOS16270.1 - 0.068 13.1 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle SecA_DEAD PF07517.9 KOS16270.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain SNF2_N PF00176.18 KOS16271.1 - 7.8e-84 280.9 1.7 1.9e-83 279.7 1.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS16271.1 - 1.1e-18 66.8 0.0 5e-17 61.5 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 KOS16271.1 - 6.4e-18 64.4 0.0 1.9e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.8 KOS16271.1 - 7.4e-17 60.9 7.2 7.4e-17 60.9 5.0 3.3 2 0 0 2 2 2 1 HSA SnAC PF14619.1 KOS16271.1 - 5.5e-15 55.2 0.6 5.5e-15 55.2 0.4 3.8 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 KOS16271.1 - 9.8e-08 31.2 0.8 9.8e-08 31.2 0.6 3.3 3 0 0 3 3 3 1 QLQ zf-C2H2 PF00096.21 KOS16273.1 - 2.5e-07 30.6 19.9 2.7e-05 24.2 1.0 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KOS16273.1 - 5e-07 29.7 3.7 5e-07 29.7 2.5 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KOS16273.1 - 5.4e-07 29.5 11.1 0.00053 20.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KOS16273.1 - 0.0033 17.2 1.8 0.0094 15.8 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KOS16273.1 - 5.6 7.2 7.4 6.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PTR2 PF00854.16 KOS16274.1 - 4.4e-30 104.7 13.3 7.1e-30 104.0 6.4 2.7 1 1 1 2 2 2 1 POT family MFS_1 PF07690.11 KOS16274.1 - 6.9e-05 21.7 32.0 0.00026 19.8 18.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.22 KOS16275.1 - 3.1e-68 225.5 0.0 1.3e-22 79.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.7 KOS16275.1 - 0.04 14.1 0.1 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 The GLUG motif DUF2813 PF11398.3 KOS16275.1 - 0.053 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) RRM_1 PF00076.17 KOS16276.1 - 1.9e-38 129.9 0.0 2.3e-18 65.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16276.1 - 1.6e-33 114.4 0.1 2.2e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16276.1 - 5.5e-14 51.7 0.0 7.1e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Grp1_Fun34_YaaH PF01184.14 KOS16277.1 - 9.8e-80 266.7 18.0 1.2e-79 266.4 12.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GST_N PF02798.15 KOS16278.1 - 6.5e-12 45.4 0.0 1.6e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KOS16278.1 - 9.2e-11 41.5 0.0 2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KOS16278.1 - 1.2e-10 41.4 0.0 4.2e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Noc2 PF03715.8 KOS16279.1 - 5.4e-105 350.5 0.4 7.7e-105 350.0 0.3 1.2 1 0 0 1 1 1 1 Noc2p family SDA1 PF05285.7 KOS16279.1 - 0.7 9.1 20.3 1.3 8.2 14.1 1.5 1 0 0 1 1 1 0 SDA1 WD40 PF00400.27 KOS16280.1 - 1.2e-55 183.4 1.4 3.8e-11 42.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KOS16280.1 - 1.7e-10 39.9 4.2 3e-10 39.1 2.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 KOS16280.1 - 0.00098 17.3 0.8 0.069 11.2 0.1 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KOS16280.1 - 0.015 14.4 0.5 2.8 6.9 0.0 3.2 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Pex14_N PF04695.8 KOS16281.1 - 7.3e-33 113.5 6.5 2.1e-31 108.7 0.2 3.5 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 KOS16281.1 - 0.00013 21.6 3.0 0.00019 21.0 2.1 1.2 1 0 0 1 1 1 1 IncA protein HemX PF04375.9 KOS16281.1 - 0.0016 17.1 0.1 0.002 16.7 0.1 1.3 1 0 0 1 1 1 1 HemX AAA_32 PF13654.1 KOS16281.1 - 0.012 14.3 3.0 0.016 13.9 2.0 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 KOS16281.1 - 0.013 15.6 2.8 0.019 15.1 1.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LXG PF04740.7 KOS16281.1 - 0.021 14.6 4.6 0.031 14.0 3.2 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily AAA_13 PF13166.1 KOS16281.1 - 0.025 13.0 1.9 0.034 12.6 1.3 1.0 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KOS16281.1 - 0.026 11.8 9.5 0.033 11.5 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.7 KOS16281.1 - 0.027 12.9 2.8 0.85 7.9 3.2 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family PaaA_PaaC PF05138.7 KOS16281.1 - 0.037 12.9 0.7 0.051 12.5 0.5 1.2 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein CALCOCO1 PF07888.6 KOS16281.1 - 0.051 11.8 6.2 0.072 11.3 4.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 KOS16281.1 - 0.059 12.8 8.2 0.085 12.3 5.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 KOS16281.1 - 0.059 12.5 1.1 0.097 11.8 0.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ERM PF00769.14 KOS16281.1 - 0.063 12.8 9.3 0.11 12.0 6.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GvpL_GvpF PF06386.6 KOS16281.1 - 0.11 12.0 2.7 0.14 11.6 1.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4235 PF14019.1 KOS16281.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Transposase_22 PF02994.9 KOS16281.1 - 0.11 10.9 3.4 0.17 10.3 2.4 1.3 1 0 0 1 1 1 0 L1 transposable element DUF763 PF05559.6 KOS16281.1 - 0.13 11.1 0.7 0.19 10.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Hemerythrin PF01814.18 KOS16281.1 - 0.16 12.1 6.1 1.6 8.8 0.5 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain ALIX_LYPXL_bnd PF13949.1 KOS16281.1 - 0.19 10.6 9.2 0.2 10.5 5.0 1.7 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV CENP-Q PF13094.1 KOS16281.1 - 0.22 11.5 10.5 0.34 10.9 7.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 KOS16281.1 - 0.29 10.0 4.7 0.49 9.2 3.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 KOS16281.1 - 0.36 11.2 10.5 3.1 8.2 3.0 3.6 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.1 KOS16281.1 - 0.42 10.5 11.2 0.99 9.3 7.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.8 KOS16281.1 - 0.52 9.3 3.4 0.72 8.8 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein FliD_N PF02465.13 KOS16281.1 - 0.81 10.0 6.0 2.7 8.4 2.1 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus APG6 PF04111.7 KOS16281.1 - 1 8.3 10.0 2.6 6.9 7.1 1.5 2 0 0 2 2 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 KOS16281.1 - 1.4 9.3 5.8 3 8.3 0.4 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 KOS16281.1 - 1.5 8.9 5.9 7.4 6.7 3.3 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Med9 PF07544.8 KOS16281.1 - 1.5 8.5 5.8 1 9.1 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Bud13 PF09736.4 KOS16281.1 - 1.6 8.9 6.5 2.4 8.4 4.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex ATP-synt_B PF00430.13 KOS16281.1 - 1.8 8.3 7.6 3 7.6 5.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Uds1 PF15456.1 KOS16281.1 - 2.6 8.0 8.6 20 5.2 0.5 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DUF1664 PF07889.7 KOS16281.1 - 2.7 7.7 7.8 16 5.3 4.8 2.6 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF2317 PF10079.4 KOS16281.1 - 2.9 6.3 6.7 5.5 5.4 4.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) V-SNARE PF05008.10 KOS16281.1 - 5.3 7.2 8.0 3.9 7.7 3.8 2.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Mnd1 PF03962.10 KOS16281.1 - 6.9 6.2 9.9 17 5.0 6.9 1.6 1 1 0 1 1 1 0 Mnd1 family Acetyltransf_1 PF00583.19 KOS16283.1 - 4.1e-16 58.7 0.0 6.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KOS16283.1 - 2.1e-06 27.8 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KOS16283.1 - 5.8e-05 23.1 0.0 9.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS16283.1 - 0.00029 20.7 0.0 0.00038 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KOS16283.1 - 0.00029 20.5 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KOS16283.1 - 0.00037 20.6 0.0 0.00052 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KOS16283.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS16283.1 - 0.009 15.8 0.0 0.038 13.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Aa_trans PF01490.13 KOS16284.1 - 7e-79 265.2 28.9 9.4e-79 264.7 20.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PfkB PF00294.19 KOS16285.1 - 2.2e-63 214.1 1.3 2.7e-63 213.9 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KOS16285.1 - 3e-06 26.6 0.0 6.6e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Toxin_47 PF15527.1 KOS16285.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Putative toxin 47 DUF3947 PF13135.1 KOS16285.1 - 0.073 13.2 1.7 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) COQ7 PF03232.8 KOS16286.1 - 2.2e-59 199.7 1.0 2.7e-59 199.4 0.7 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KOS16286.1 - 0.0033 17.7 0.1 0.0085 16.4 0.0 1.7 2 0 0 2 2 2 1 Rubrerythrin DUF3849 PF12960.2 KOS16286.1 - 0.015 15.2 0.3 0.06 13.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3849) AOX PF01786.12 KOS16286.1 - 0.016 14.6 0.7 0.18 11.1 0.4 2.1 1 1 0 1 1 1 0 Alternative oxidase WD40 PF00400.27 KOS16287.1 - 4e-21 74.0 4.8 0.00061 19.5 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 KOS16287.1 - 8.4e-05 22.3 0.0 8.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) DUF4402 PF14352.1 KOS16287.1 - 0.096 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Plant_all_beta PF10532.4 KOS16287.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Plant specific N-all beta domain NDK PF00334.14 KOS16288.1 - 6.8e-57 191.0 0.0 7.7e-57 190.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KOS16288.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Pkr1 PF08636.5 KOS16289.1 - 2.9e-15 56.0 2.3 3.3e-15 55.8 1.6 1.0 1 0 0 1 1 1 1 ER protein Pkr1 DUF4229 PF14012.1 KOS16289.1 - 0.00042 20.1 0.2 0.00052 19.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) YfhO PF09586.5 KOS16289.1 - 0.016 13.2 0.4 0.018 13.1 0.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TRAM_LAG1_CLN8 PF03798.11 KOS16289.1 - 0.024 14.1 0.2 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 TLC domain Cytochrom_B_N PF00033.14 KOS16289.1 - 0.047 13.0 2.4 0.9 8.8 0.3 2.0 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Fmp27 PF10344.4 KOS16289.1 - 0.062 10.9 0.1 0.058 11.0 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF1049 PF06305.6 KOS16289.1 - 0.1 12.1 4.8 0.16 11.4 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Tox-PL-2 PF15643.1 KOS16289.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Papain fold toxin 2 DUF3169 PF11368.3 KOS16289.1 - 0.14 11.3 3.8 0.17 11.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF383 PF04063.9 KOS16290.1 - 2.3e-58 196.9 0.1 8.3e-58 195.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KOS16290.1 - 5.1e-19 67.5 1.6 8.2e-19 66.9 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) RabGAP-TBC PF00566.13 KOS16291.1 - 7.5e-48 162.8 0.2 1.2e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 KOS16291.1 - 5.4e-07 29.0 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 KOS16291.1 - 0.069 13.0 0.6 0.77 9.8 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 KOS16291.1 - 0.072 13.2 2.1 0.22 11.7 0.2 2.8 3 1 0 3 3 3 0 EF-hand domain pair Pkinase PF00069.20 KOS16292.1 - 1.2e-62 211.3 0.0 1.5e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16292.1 - 8e-35 120.1 0.0 4.9e-33 114.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS16292.1 - 4.9e-07 28.9 0.0 7.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KOS16292.1 - 7.1e-06 25.9 1.8 0.011 15.5 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KOS16292.1 - 3.2e-05 23.1 0.1 0.0012 17.9 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KOS16292.1 - 0.022 14.1 0.0 0.083 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KOS16292.1 - 0.025 13.9 0.1 0.047 13.0 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KOS16292.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ssu72 PF04722.8 KOS16294.1 - 2e-81 271.9 0.0 2.4e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 KOS16294.1 - 0.03 14.6 1.1 0.086 13.1 0.1 2.0 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase FadR_C PF07840.7 KOS16294.1 - 0.07 12.7 0.1 0.099 12.2 0.1 1.2 1 0 0 1 1 1 0 FadR C-terminal domain DUF1890 PF09001.6 KOS16294.1 - 0.13 12.2 0.1 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) E1_dh PF00676.15 KOS16295.1 - 1.4e-111 372.0 0.3 1.7e-111 371.7 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KOS16295.1 - 7.3e-05 21.8 0.1 0.0002 20.3 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 KOS16295.1 - 0.0089 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain MFS_1 PF07690.11 KOS16296.1 - 3.1e-20 72.2 29.8 3.9e-20 71.8 20.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KOS16296.1 - 4.7e-15 55.1 14.1 1.6e-14 53.3 9.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Ribosomal_S14 PF00253.16 KOS16297.1 - 7.4e-22 76.4 4.5 8.1e-22 76.3 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 KOS16297.1 - 0.19 11.8 5.5 2.5 8.2 0.9 2.2 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.5 KOS16297.1 - 0.28 10.6 1.8 0.42 10.1 1.2 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain Cyclin_N PF00134.18 KOS16298.1 - 2.2e-37 127.4 0.2 4.5e-37 126.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KOS16298.1 - 1.2e-09 38.0 0.8 3.6e-09 36.5 0.6 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Glycoprotein_G PF00802.14 KOS16298.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Clathrin_H_link PF13838.1 KOS16298.1 - 0.24 11.3 2.0 6.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Clathrin-H-link Abhydro_lipase PF04083.11 KOS16299.1 - 3.1e-14 52.0 0.0 6.5e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KOS16299.1 - 2.9e-08 33.8 2.4 5.1e-08 33.0 1.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KOS16299.1 - 3.6e-07 30.0 0.0 6.7e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS16299.1 - 7.8e-07 28.8 0.5 4.7e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.9 KOS16299.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Redoxin PF08534.5 KOS16300.1 - 0.00023 20.7 0.0 0.00044 19.8 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KOS16300.1 - 0.00034 20.2 0.0 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Glyco_transf_22 PF03901.12 KOS16301.1 - 9.3e-30 103.9 12.4 1.1e-29 103.7 8.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family EXS PF03124.9 KOS16302.1 - 1.6e-65 221.4 14.7 1.8e-65 221.2 10.2 1.0 1 0 0 1 1 1 1 EXS family Homeobox PF00046.24 KOS16303.1 - 1.3e-14 53.5 2.7 2.4e-14 52.6 1.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KOS16303.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_3 PF01381.17 KOS16303.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix AAR2 PF05282.6 KOS16304.1 - 6.3e-55 186.5 0.0 8.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DUF1138 PF06592.8 KOS16304.1 - 0.13 12.2 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) zf-C3HC4 PF00097.20 KOS16305.1 - 1.8e-08 33.9 7.8 1e-07 31.5 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KOS16305.1 - 2.3e-08 33.7 3.0 2.3e-08 33.7 2.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KOS16305.1 - 5.6e-08 32.6 9.9 4.8e-07 29.6 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS16305.1 - 2.3e-07 30.5 11.6 1.3e-06 28.1 4.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KOS16305.1 - 1e-06 28.4 10.2 1.7e-06 27.8 4.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING SAP PF02037.22 KOS16305.1 - 1.9e-06 27.2 0.1 3.7e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.1 KOS16305.1 - 2.6e-06 27.0 8.4 2.3e-05 23.9 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS16305.1 - 7.3e-06 25.6 11.2 1.4e-05 24.6 4.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 KOS16305.1 - 0.00014 21.3 2.9 0.00076 18.9 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KOS16305.1 - 0.00056 19.3 8.0 0.001 18.4 2.9 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 KOS16305.1 - 0.0012 18.6 1.8 0.0065 16.2 0.6 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_5 PF13719.1 KOS16305.1 - 0.0016 18.0 0.6 11 5.7 0.0 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.1 KOS16305.1 - 0.0043 16.6 5.8 0.26 10.8 1.7 2.5 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KOS16305.1 - 0.016 15.3 5.0 0.23 11.5 1.5 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C2HC_2 PF13913.1 KOS16305.1 - 0.017 14.7 0.1 0.054 13.1 0.0 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 KOS16305.1 - 0.056 13.1 3.6 23 4.7 0.0 3.8 4 0 0 4 4 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 KOS16305.1 - 0.061 13.3 2.4 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 zinc-finger zf-Di19 PF05605.7 KOS16305.1 - 0.13 12.4 3.9 0.23 11.5 0.0 2.6 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.16 KOS16305.1 - 0.18 11.7 10.8 1.4 8.8 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KOS16305.1 - 0.28 10.9 8.7 0.099 12.3 2.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C2H2_4 PF13894.1 KOS16305.1 - 2.8 8.4 0.0 2.8 8.4 0.0 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-RING_2 PF13639.1 KOS16307.1 - 3.3e-05 23.6 6.6 5.2e-05 22.9 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 KOS16307.1 - 0.00045 19.8 1.8 0.00045 19.8 1.3 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KOS16307.1 - 0.0045 16.6 2.1 0.0045 16.6 1.5 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KOS16307.1 - 0.0079 15.8 7.7 0.03 13.9 5.3 1.9 1 1 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 KOS16307.1 - 0.029 14.3 3.2 0.029 14.3 2.2 1.5 2 0 0 2 2 1 0 FANCL C-terminal domain C1_2 PF03107.11 KOS16307.1 - 0.11 12.6 4.9 0.17 12.0 3.4 1.3 1 0 0 1 1 1 0 C1 domain Mitofilin PF09731.4 KOS16307.1 - 0.15 10.6 5.1 0.16 10.5 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_L37ae PF01780.14 KOS16307.1 - 0.26 11.1 6.4 0.86 9.5 1.3 2.5 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-MIZ PF02891.15 KOS16307.1 - 0.35 10.4 8.4 1.8 8.1 0.1 2.8 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger C1_3 PF07649.7 KOS16307.1 - 0.36 10.8 3.6 0.77 9.8 2.5 1.6 1 0 0 1 1 1 0 C1-like domain zf-4CXXC_R1 PF10497.4 KOS16307.1 - 1 9.4 5.8 6.1 7.0 0.3 2.5 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_2 PF13923.1 KOS16307.1 - 1.2 9.2 7.1 2.7 8.1 4.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.10 KOS16307.1 - 1.2 8.7 6.0 6.6 6.3 0.1 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger RINGv PF12906.2 KOS16307.1 - 1.5 8.9 8.7 2.4 8.2 6.0 1.4 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.2 KOS16307.1 - 2.2 8.4 8.9 0.45 10.6 3.4 1.9 2 1 0 2 2 1 0 RING-H2 zinc finger Tnp_zf-ribbon_2 PF13842.1 KOS16307.1 - 3.3 8.2 8.4 0.34 11.3 2.3 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Ctr PF04145.10 KOS16308.1 - 3.4e-28 98.5 0.1 5.1e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family eIF3_subunit PF08597.5 KOS16309.1 - 9.6e-36 123.5 23.2 1.1e-35 123.4 16.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Lon_C PF05362.8 KOS16310.1 - 4.3e-65 218.8 0.0 7e-65 218.1 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KOS16310.1 - 1.3e-24 86.8 0.0 2.6e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KOS16310.1 - 2.2e-09 37.1 0.0 5.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KOS16310.1 - 6.6e-09 35.3 0.0 1.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KOS16310.1 - 3.2e-05 23.9 0.5 0.00021 21.3 0.1 2.4 2 1 1 3 3 2 1 AAA ATPase domain LON PF02190.11 KOS16310.1 - 4.2e-05 23.3 0.0 9.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_17 PF13207.1 KOS16310.1 - 0.00019 22.2 0.0 0.0005 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS16310.1 - 0.00026 20.6 0.1 0.001 18.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_PrkA PF08298.6 KOS16310.1 - 0.00035 19.3 0.0 0.00055 18.7 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 KOS16310.1 - 0.00046 20.3 0.1 0.011 15.8 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KOS16310.1 - 0.00056 19.3 0.2 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KOS16310.1 - 0.00057 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KOS16310.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KOS16310.1 - 0.0021 17.9 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 KOS16310.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.7 KOS16310.1 - 0.012 14.6 0.0 0.086 11.8 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KOS16310.1 - 0.014 14.5 0.6 0.077 12.1 0.0 2.4 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KOS16310.1 - 0.014 14.0 0.1 0.19 10.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_3 PF07726.6 KOS16310.1 - 0.015 14.9 0.1 0.096 12.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KOS16310.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KOS16310.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KOS16310.1 - 0.018 15.0 0.1 0.097 12.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 KOS16310.1 - 0.018 14.4 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.7 KOS16310.1 - 0.047 13.3 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 KOS16310.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 KOS16310.1 - 0.059 12.2 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KOS16310.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KOS16310.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KOS16310.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KOS16310.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KOS16310.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 KOS16310.1 - 0.13 11.9 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CCDC-167 PF15188.1 KOS16310.1 - 0.14 12.1 1.5 0.33 10.9 1.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ABC_tran PF00005.22 KOS16310.1 - 0.15 12.3 0.1 0.64 10.3 0.0 2.1 3 0 0 3 3 1 0 ABC transporter SKI PF01202.17 KOS16310.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Parvo_NS1 PF01057.12 KOS16310.1 - 0.22 10.3 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 KOS16310.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KOS16310.1 - 0.48 10.7 0.0 0.78 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glucosamine_iso PF01182.15 KOS16311.1 - 9.1e-65 218.1 0.0 1.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Acetyltransf_1 PF00583.19 KOS16312.1 - 4.2e-15 55.5 0.1 7.1e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KOS16312.1 - 2.4e-06 27.1 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KOS16312.1 - 9.9e-06 25.6 0.1 2.9e-05 24.1 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS16312.1 - 0.00039 20.5 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KOS16312.1 - 0.00063 19.5 0.3 0.0015 18.4 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KOS16312.1 - 0.0035 17.2 0.2 0.0046 16.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KOS16312.1 - 0.025 14.2 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.1 KOS16312.1 - 0.054 13.4 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPS PF01242.14 KOS16312.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Ank_2 PF12796.2 KOS16313.1 - 9.5e-17 61.1 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KOS16313.1 - 4.2e-15 55.7 0.9 2.5e-11 43.7 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS16313.1 - 2.2e-12 46.0 1.4 4.4e-08 32.5 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KOS16313.1 - 1.7e-09 36.9 0.2 2.2e-05 24.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS16313.1 - 2.6e-09 37.0 3.2 1.1e-06 28.6 0.5 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Methyltransf_18 PF12847.2 KOS16313.1 - 3.2e-05 24.4 0.0 0.0092 16.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Adaptin_N PF01602.15 KOS16314.1 - 5.9e-142 473.6 17.6 7e-142 473.4 12.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KOS16314.1 - 2e-18 66.7 0.0 3.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KOS16314.1 - 3.6e-06 27.1 7.0 0.56 10.5 0.1 5.5 4 3 2 6 6 6 3 HEAT repeats HEAT PF02985.17 KOS16314.1 - 0.00085 19.2 1.3 22 5.4 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 KOS16314.1 - 0.0012 18.7 9.6 0.002 17.9 0.8 4.1 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 KOS16314.1 - 0.0033 17.0 0.3 0.0033 17.0 0.2 3.5 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.3 KOS16314.1 - 1.2 8.3 8.3 3.4 6.9 0.1 3.3 2 1 1 3 3 3 0 CLASP N terminal Arf PF00025.16 KOS16315.1 - 5.6e-64 214.5 0.0 1.2e-63 213.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS16315.1 - 2e-12 46.6 0.0 2.5e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KOS16315.1 - 1.4e-10 40.8 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KOS16315.1 - 3.3e-10 39.1 0.4 2.8e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KOS16315.1 - 4.9e-10 38.9 0.0 5.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KOS16315.1 - 1.1e-05 25.2 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KOS16315.1 - 1.9e-05 25.1 0.0 2.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein 6PF2K PF01591.13 KOS16315.1 - 0.023 13.7 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 KOS16315.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 L27 domain FeoB_N PF02421.13 KOS16315.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Ribosomal_L37e PF01907.14 KOS16316.1 - 3.6e-25 87.5 12.8 5.7e-25 86.8 8.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KOS16316.1 - 0.0036 17.0 3.5 0.0058 16.4 2.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 KOS16316.1 - 0.037 13.7 0.1 0.04 13.5 0.1 1.1 1 0 0 1 1 1 0 SelR domain zf-RING_5 PF14634.1 KOS16316.1 - 0.15 11.8 4.0 0.21 11.3 2.7 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS16316.1 - 0.62 9.7 6.3 0.96 9.1 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 KOS16316.1 - 6.1 6.3 11.2 4.1 6.8 1.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Pox_MCEL PF03291.11 KOS16317.1 - 2.1e-78 263.5 0.0 2.5e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_11 PF08241.7 KOS16317.1 - 9.9e-11 41.9 0.0 2.1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS16317.1 - 1.5e-10 40.9 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16317.1 - 1.6e-10 41.5 0.0 4.6e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16317.1 - 2.8e-09 37.3 0.0 6.7e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KOS16317.1 - 1.3e-08 34.6 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS16317.1 - 5.4e-08 33.1 0.0 2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KOS16317.1 - 0.00017 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KOS16317.1 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KOS16317.1 - 0.0039 16.2 0.0 0.0091 14.9 0.0 1.6 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubiq_cyt_C_chap PF03981.7 KOS16318.1 - 2.9e-31 108.1 0.0 1.4e-30 106.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DSPc PF00782.15 KOS16319.1 - 3.6e-27 94.5 0.0 5.9e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KOS16319.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KOS16319.1 - 0.0037 16.6 0.0 0.0089 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KOS16319.1 - 0.011 15.9 0.1 0.062 13.5 0.0 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family Rhodanese PF00581.15 KOS16319.1 - 0.014 15.7 0.0 1 9.7 0.0 2.5 2 1 0 2 2 2 0 Rhodanese-like domain tRNA-synt_2d PF01409.15 KOS16320.1 - 7.6e-86 287.3 0.0 1.1e-85 286.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KOS16320.1 - 2.7e-05 23.8 0.0 6.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KOS16320.1 - 0.00025 19.9 1.0 0.002 16.9 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) RNA_pol_A_bac PF01000.21 KOS16321.1 - 2.1e-29 101.9 0.0 4.9e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KOS16321.1 - 3.1e-16 58.2 0.0 4.1e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.23 KOS16322.1 - 4.2e-28 97.6 0.0 6.1e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.19 KOS16323.1 - 4.6e-33 114.7 26.0 7.7e-33 114.0 18.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KOS16323.1 - 6.9e-11 41.7 0.0 1.9e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3045 PF11243.3 KOS16323.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Pkinase PF00069.20 KOS16324.1 - 1.6e-71 240.4 0.0 2.4e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16324.1 - 9.2e-40 136.3 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS16324.1 - 8.9e-07 28.1 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 KOS16324.1 - 0.00031 20.1 0.1 0.00056 19.3 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 KOS16324.1 - 0.025 13.9 0.2 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Peptidase_M3 PF01432.15 KOS16325.1 - 3.8e-127 425.1 0.0 5e-127 424.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 PAP_assoc PF03828.14 KOS16326.1 - 2.3e-15 56.2 0.0 4.5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KOS16326.1 - 8.2e-09 35.6 0.0 2.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain RNA_pol_L_2 PF13656.1 KOS16327.1 - 3.7e-26 90.3 0.0 4.7e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KOS16327.1 - 1.4e-13 49.7 0.0 1.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GRASP55_65 PF04495.9 KOS16328.1 - 3.4e-50 169.6 0.0 4.1e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 KOS16328.1 - 0.0061 16.3 0.0 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ_2 PF13180.1 KOS16328.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Complex1_51K PF01512.12 KOS16329.1 - 4.1e-48 162.9 0.0 5.8e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KOS16329.1 - 2.3e-18 65.0 0.2 4.6e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KOS16329.1 - 4.5e-08 32.8 0.0 1.3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 SLBB domain DUF4111 PF13427.1 KOS16329.1 - 0.1 12.4 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) FA_hydroxylase PF04116.8 KOS16330.1 - 5e-15 55.8 20.5 5e-15 55.8 14.2 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Biotin_lipoyl PF00364.17 KOS16331.1 - 6.3e-21 73.7 0.8 1.2e-20 72.8 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KOS16331.1 - 2.4e-05 23.8 0.0 7.1e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KOS16331.1 - 0.026 14.1 0.1 0.084 12.5 0.0 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like HlyD_2 PF12700.2 KOS16331.1 - 0.11 11.6 0.2 6.6 5.7 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Ribosomal_L34 PF00468.12 KOS16332.1 - 5.8e-16 57.8 9.4 8.6e-16 57.3 6.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Diphthamide_syn PF01866.12 KOS16333.1 - 1.3e-89 300.4 0.0 4.2e-55 187.1 0.0 2.7 1 1 1 2 2 2 2 Putative diphthamide synthesis protein GMC_oxred_N PF00732.14 KOS16334.1 - 1.1e-62 211.8 0.2 2.1e-62 210.9 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS16334.1 - 2.5e-34 118.6 0.0 7.9e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KOS16334.1 - 0.00013 21.0 0.1 0.00025 20.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KOS16334.1 - 0.00016 20.7 0.0 0.00041 19.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KOS16334.1 - 0.0002 21.2 0.3 0.00043 20.0 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KOS16334.1 - 0.00072 19.4 0.0 0.0021 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS16334.1 - 0.0012 18.7 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KOS16334.1 - 0.0023 16.8 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KOS16334.1 - 0.014 13.8 0.3 0.094 11.1 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 KOS16334.1 - 0.023 14.6 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KOS16334.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KOS16335.1 - 1.9e-72 243.8 0.9 2.5e-72 243.5 0.6 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS16335.1 - 1.5e-35 122.6 0.0 2.9e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KOS16335.1 - 1.4e-07 31.7 0.0 0.023 14.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KOS16335.1 - 5.2e-07 28.8 0.0 0.00082 18.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS16335.1 - 4.3e-05 22.5 1.7 0.0035 16.2 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KOS16335.1 - 0.00024 21.0 0.5 0.00072 19.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KOS16335.1 - 0.00052 19.9 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KOS16335.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KOS16335.1 - 0.014 13.8 0.7 0.032 12.7 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 KOS16335.1 - 0.02 13.9 0.1 0.04 12.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KOS16335.1 - 0.055 13.8 1.2 0.37 11.2 0.2 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KOS16335.1 - 0.16 11.9 2.1 0.6 10.1 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain SURF1 PF02104.10 KOS16336.1 - 4.8e-44 150.7 0.0 1.4e-43 149.1 0.0 1.7 1 1 0 1 1 1 1 SURF1 family TPR_1 PF00515.23 KOS16337.1 - 3.5e-56 184.6 8.0 9e-06 25.0 0.4 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KOS16337.1 - 5.8e-49 163.6 11.5 1.5e-11 43.7 0.0 6.6 3 2 1 6 6 6 6 TPR repeat TPR_2 PF07719.12 KOS16337.1 - 3.5e-46 151.4 6.8 8.9e-05 22.1 0.2 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KOS16337.1 - 3e-37 123.5 10.4 0.00024 20.6 0.0 10.2 7 1 3 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 KOS16337.1 - 4.1e-33 110.8 0.1 0.0002 21.6 0.0 9.7 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KOS16337.1 - 2.8e-30 104.0 7.3 4.4e-06 26.5 0.0 6.6 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.1 KOS16337.1 - 2.1e-26 92.0 0.1 9.4e-06 25.8 0.0 7.0 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 KOS16337.1 - 3.2e-24 82.7 5.7 0.0028 17.3 0.0 9.5 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KOS16337.1 - 2.6e-23 80.2 8.0 0.0076 16.3 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KOS16337.1 - 8.3e-23 80.4 5.3 7.5e-05 23.2 0.3 6.9 4 1 4 9 9 8 7 Tetratricopeptide repeat TPR_6 PF13174.1 KOS16337.1 - 7.5e-21 73.1 5.6 0.13 12.7 1.3 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 KOS16337.1 - 4.4e-16 58.4 6.9 0.00049 19.9 0.0 7.0 3 1 4 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 KOS16337.1 - 2e-12 47.0 4.7 1.8e-05 24.7 0.1 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KOS16337.1 - 4.6e-09 35.7 2.4 0.013 14.5 0.0 4.7 1 1 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 KOS16337.1 - 0.00026 20.9 0.6 1.9 8.4 0.4 4.0 2 2 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 KOS16337.1 - 0.016 15.0 3.1 4.1 7.3 0.1 4.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Tcf25 PF04910.9 KOS16337.1 - 0.11 11.4 0.8 3.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Transcriptional repressor TCF25 TPR_10 PF13374.1 KOS16337.1 - 0.13 12.1 7.1 1.9 8.5 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Herpes_U47 PF05467.6 KOS16337.1 - 0.39 8.4 0.0 0.63 7.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Kinesin PF00225.18 KOS16338.1 - 4.4e-103 344.4 0.1 8.8e-103 343.5 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.27 KOS16338.1 - 1.2e-54 180.2 35.2 2.9e-12 45.9 0.5 8.2 9 0 0 9 9 9 7 WD domain, G-beta repeat eIF2A PF08662.6 KOS16338.1 - 2.2e-05 24.2 0.0 0.0012 18.6 0.0 3.0 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3939 PF13075.1 KOS16338.1 - 0.016 14.8 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Cys_Met_Meta_PP PF01053.15 KOS16339.1 - 8.1e-118 393.0 0.0 1.3e-117 392.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 KOS16339.1 - 1.4e-17 63.4 0.0 9e-17 60.9 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KOS16339.1 - 2.8e-06 27.4 0.1 5.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KOS16339.1 - 0.027 13.7 0.1 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature CybS PF05328.7 KOS16340.1 - 5.5e-33 113.4 0.1 7.5e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 CybS DUF423 PF04241.10 KOS16341.1 - 9.4e-25 86.3 4.3 1.3e-24 85.9 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Arf PF00025.16 KOS16342.1 - 5.4e-64 214.6 0.0 6.3e-64 214.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KOS16342.1 - 3.9e-15 55.5 0.0 5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KOS16342.1 - 5.3e-12 45.1 0.4 2.2e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KOS16342.1 - 5.4e-11 43.0 0.0 6.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KOS16342.1 - 6.6e-10 38.6 0.0 7.6e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KOS16342.1 - 4.1e-09 36.4 0.0 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KOS16342.1 - 6e-08 32.1 0.0 6.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KOS16342.1 - 1.4e-07 31.1 0.0 2.5e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KOS16342.1 - 0.0057 15.9 0.2 0.013 14.8 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B WD40 PF00400.27 KOS16343.1 - 3.7e-06 26.6 18.8 0.0002 21.1 0.0 7.7 9 0 0 9 9 9 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KOS16343.1 - 0.079 13.2 2.3 0.79 10.0 0.2 3.7 4 0 0 4 4 4 0 PQQ-like domain mIF3 PF14877.1 KOS16344.1 - 1.5e-05 24.4 0.2 7e-05 22.2 0.1 2.0 1 1 1 2 2 2 1 Mitochondrial translation initiation factor IF3_N PF05198.11 KOS16344.1 - 0.00089 19.1 0.3 0.0023 17.8 0.1 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 KOS16344.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Spc24 PF08286.6 KOS16345.1 - 3.3e-12 46.1 1.0 3.9e-12 45.9 0.7 1.2 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 TMCO5 PF14992.1 KOS16345.1 - 0.063 12.4 1.3 0.088 11.9 0.9 1.3 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 KOS16345.1 - 0.083 10.7 0.6 0.086 10.6 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ino80_Iec3 PF14612.1 KOS16346.1 - 0.00042 20.4 1.1 0.00059 19.9 0.7 1.3 1 1 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF972 PF06156.8 KOS16346.1 - 0.012 15.8 1.2 0.016 15.5 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RmuC PF02646.11 KOS16346.1 - 0.037 12.8 0.2 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 RmuC family PspA_IM30 PF04012.7 KOS16346.1 - 0.04 13.2 2.3 0.057 12.7 1.2 1.4 1 1 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.6 KOS16346.1 - 0.04 12.5 0.3 0.05 12.2 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4424 PF14415.1 KOS16346.1 - 0.045 13.2 0.2 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Pup PF05639.6 KOS16346.1 - 0.12 12.9 2.0 0.15 12.5 0.2 2.1 2 0 0 2 2 2 0 Pup-like protein Hid1 PF12722.2 KOS16346.1 - 0.13 9.9 2.4 0.15 9.7 1.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CHD5 PF04420.9 KOS16346.1 - 0.13 11.8 0.8 0.2 11.3 0.6 1.2 1 0 0 1 1 1 0 CHD5-like protein Sigma70_ner PF04546.8 KOS16346.1 - 2.3 7.8 7.5 1.2 8.6 3.4 1.8 1 1 1 2 2 2 0 Sigma-70, non-essential region Ribonuclease_P PF00825.13 KOS16347.1 - 7.5e-05 22.6 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease P RRM_6 PF14259.1 KOS16349.1 - 2.1e-19 69.2 0.0 2.1e-11 43.6 0.0 3.3 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16349.1 - 8.4e-15 54.3 0.0 1.9e-09 37.2 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS16349.1 - 1.4e-14 53.4 0.0 3.5e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Drc1-Sld2 PF11719.3 KOS16350.1 - 1.5e-10 40.7 18.0 2.3e-10 40.1 5.7 2.3 1 1 1 2 2 2 2 DNA replication and checkpoint protein DEAD PF00270.24 KOS16351.1 - 5.5e-37 126.8 0.1 3.6e-36 124.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16351.1 - 6.8e-20 70.7 0.1 1.3e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2 PF00096.21 KOS16352.1 - 1.4e-05 25.1 6.3 0.012 15.9 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16352.1 - 0.00013 22.0 8.3 0.0057 16.8 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KOS16352.1 - 0.067 13.4 0.3 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type V-ATPase_H_N PF03224.9 KOS16353.1 - 1.4e-57 195.1 0.1 2.7e-55 187.6 0.0 2.3 2 1 0 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 KOS16353.1 - 2.1e-34 117.9 0.1 9e-34 115.9 0.1 2.1 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.1 KOS16353.1 - 8.5e-05 22.7 0.9 0.0064 16.7 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KOS16353.1 - 0.0057 16.6 0.0 0.037 14.1 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.18 KOS16353.1 - 0.034 13.9 0.2 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat LpxD PF04613.9 KOS16353.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD PIG-U PF06728.8 KOS16354.1 - 3.3e-72 243.4 26.6 3.9e-72 243.2 18.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Nse4_C PF08743.5 KOS16355.1 - 6.9e-27 93.3 0.0 2.3e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KOS16355.1 - 1.2e-11 44.2 0.1 2.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE MFS_1 PF07690.11 KOS16358.1 - 2.3e-17 62.7 38.1 9.1e-14 50.9 10.6 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily HILPDA PF15220.1 KOS16358.1 - 0.057 13.4 1.7 0.56 10.2 0.0 2.8 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated CAP_GLY PF01302.20 KOS16359.1 - 4e-22 77.6 0.2 6.2e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain TMF_DNA_bd PF12329.3 KOS16359.1 - 0.00019 21.1 0.1 0.00019 21.1 0.1 6.7 4 1 3 7 7 7 3 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 KOS16360.1 - 6.7e-75 251.5 0.0 3.2e-40 137.9 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16360.1 - 3.5e-41 141.0 0.3 7e-19 67.9 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 KOS16360.1 - 2.6e-20 72.7 1.5 3.5e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 KOS16360.1 - 7.6e-18 64.6 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 KOS16360.1 - 1.8e-12 47.1 0.0 5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KOS16360.1 - 6.5e-05 22.7 0.2 0.00039 20.2 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KOS16360.1 - 0.00055 18.9 0.0 0.0059 15.5 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KOS16360.1 - 0.74 8.5 0.1 1.3 7.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 OTU PF02338.14 KOS16361.1 - 9.7e-18 64.9 0.0 2.2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KOS16361.1 - 5.2e-05 22.7 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain Transglut_core3 PF13471.1 KOS16361.1 - 0.89 9.3 0.0 0.89 9.3 0.0 3.3 4 0 0 4 4 4 0 Transglutaminase-like superfamily DUF3074 PF11274.3 KOS16362.1 - 6.5e-39 133.4 0.1 1.2e-38 132.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) RRM_1 PF00076.17 KOS16363.1 - 4e-13 48.7 0.0 7.7e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16363.1 - 1.1e-12 47.7 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16363.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_gE PF02480.11 KOS16363.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Aldose_epim PF01263.15 KOS16364.1 - 1.1e-24 87.1 0.0 3.2e-24 85.5 0.0 1.7 1 1 0 1 1 1 1 Aldose 1-epimerase HEAT_2 PF13646.1 KOS16365.1 - 3.5e-07 30.3 9.6 0.0034 17.6 0.7 3.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KOS16365.1 - 1e-05 25.1 5.9 0.06 13.4 0.1 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KOS16365.1 - 0.0011 19.3 13.5 0.23 11.9 1.3 4.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KOS16365.1 - 0.018 14.9 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KOS16365.1 - 0.15 11.9 1.7 0.65 9.9 0.4 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KOS16365.1 - 4.6 8.0 9.2 31 5.4 0.1 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat WD40 PF00400.27 KOS16366.1 - 3.3e-17 61.6 2.9 9.7e-07 28.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 KOS16366.1 - 0.00094 18.7 0.1 0.1 12.2 0.0 3.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KOS16366.1 - 0.025 14.2 0.0 0.85 9.2 0.0 2.7 2 1 2 4 4 3 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KOS16366.1 - 0.4 10.0 4.3 0.81 9.0 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Glyco_hydro_85 PF03644.8 KOS16367.1 - 2.8e-75 253.3 0.0 3.9e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Ribosomal_L24e PF01246.15 KOS16370.1 - 3e-29 100.6 3.3 3e-29 100.6 2.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2116 PF09889.4 KOS16370.1 - 1.8 8.4 4.5 4.1 7.2 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) GSH_synth_ATP PF03917.12 KOS16371.1 - 1.9e-103 345.9 0.0 2.7e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KOS16371.1 - 2.5e-34 117.5 0.0 4.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Mito_carr PF00153.22 KOS16373.1 - 2.5e-32 110.4 6.9 2.2e-14 52.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC1 PF03109.11 KOS16374.1 - 4.9e-23 81.3 0.0 8.8e-14 51.4 0.0 2.5 2 0 0 2 2 2 2 ABC1 family ABC_tran PF00005.22 KOS16375.1 - 5.3e-54 182.2 0.0 1.1e-30 106.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KOS16375.1 - 1.5e-47 162.3 35.1 2.1e-25 89.7 8.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KOS16375.1 - 1.6e-08 34.8 2.2 0.67 9.8 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KOS16375.1 - 6.4e-08 32.0 0.0 0.00036 19.8 0.0 3.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KOS16375.1 - 8e-05 22.0 1.1 0.2 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KOS16375.1 - 9e-05 21.9 1.7 0.04 13.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.18 KOS16375.1 - 0.00028 20.8 0.4 0.16 11.9 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KOS16375.1 - 0.00046 20.6 0.1 0.48 10.9 0.2 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KOS16375.1 - 0.00074 19.5 3.4 0.13 12.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KOS16375.1 - 0.0025 17.0 1.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KOS16375.1 - 0.0055 16.1 0.3 1.7 7.9 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain Arch_ATPase PF01637.13 KOS16375.1 - 0.0081 15.8 0.1 0.55 9.8 0.0 3.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 KOS16375.1 - 0.012 16.4 0.4 7 7.5 0.0 3.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KOS16375.1 - 0.012 14.9 0.1 0.27 10.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2453 PF10507.4 KOS16375.1 - 0.014 15.2 0.7 0.15 11.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) AAA_23 PF13476.1 KOS16375.1 - 0.015 15.5 4.9 1.8 8.8 0.2 3.0 2 1 1 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KOS16375.1 - 0.038 13.4 0.0 5.3 6.4 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 KOS16375.1 - 0.045 12.6 0.4 21 3.9 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.1 KOS16375.1 - 0.12 12.5 5.0 10 6.3 0.2 4.5 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 KOS16375.1 - 0.15 11.8 3.6 0.24 11.1 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 C2 PF00168.25 KOS16376.1 - 4e-22 77.8 0.0 4.5e-17 61.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain Ank_4 PF13637.1 KOS16377.1 - 3e-12 46.6 0.1 6.5e-07 29.7 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KOS16377.1 - 9e-12 45.1 0.3 3.9e-10 39.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KOS16377.1 - 1.5e-08 34.6 0.0 2.7e-05 24.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KOS16377.1 - 8.7e-08 31.6 0.0 0.00058 19.5 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KOS16377.1 - 6.7e-07 28.9 0.1 0.0025 17.8 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeat DBI_PRT PF02277.12 KOS16377.1 - 0.031 13.3 0.5 0.12 11.4 0.7 1.7 2 0 0 2 2 2 0 Phosphoribosyltransferase DUF2664 PF10867.3 KOS16377.1 - 0.066 13.8 0.0 0.13 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2664) ATP-cone PF03477.11 KOS16377.1 - 0.32 11.4 1.4 0.62 10.5 0.4 2.0 2 0 0 2 2 2 0 ATP cone domain Dak1 PF02733.12 KOS16378.1 - 8.1e-110 366.4 0.6 1.3e-109 365.7 0.4 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KOS16378.1 - 6.6e-49 165.9 3.6 2.4e-48 164.1 2.3 1.9 2 0 0 2 2 2 1 DAK2 domain Diphtheria_T PF02764.9 KOS16378.1 - 0.026 14.2 0.2 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain SIMPL PF04402.9 KOS16378.1 - 0.051 13.4 0.5 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) PCI PF01399.22 KOS16379.1 - 9.4e-17 61.2 0.0 2.9e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KOS16379.1 - 0.0053 16.1 0.7 0.0053 16.1 0.5 2.1 3 0 0 3 3 3 1 26S proteasome subunit RPN7 Tubulin_C PF03953.12 KOS16379.1 - 0.012 15.6 0.0 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 Tubulin C-terminal domain TIP49 PF06068.8 KOS16380.1 - 6.4e-179 594.8 3.1 7.5e-179 594.5 2.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KOS16380.1 - 1.3e-09 38.3 0.4 4.4e-07 30.1 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KOS16380.1 - 1.2e-08 34.3 1.1 2.1e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS16380.1 - 1.7e-06 28.1 0.1 0.053 13.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KOS16380.1 - 2.9e-06 27.0 0.9 0.0028 17.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 KOS16380.1 - 9.5e-06 24.6 0.3 1.7e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KOS16380.1 - 1.5e-05 25.0 0.0 7.4e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 KOS16380.1 - 2.6e-05 23.5 2.1 0.00082 18.5 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KOS16380.1 - 0.00013 21.5 0.1 0.13 11.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 KOS16380.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KOS16380.1 - 0.00038 19.9 0.0 0.00088 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KOS16380.1 - 0.0016 18.3 0.1 1.4 8.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KOS16380.1 - 0.0017 19.1 0.0 0.0055 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KOS16380.1 - 0.0049 16.4 0.2 0.0092 15.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KOS16380.1 - 0.0059 16.0 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KOS16380.1 - 0.0076 15.7 0.6 0.55 9.6 0.0 2.6 2 1 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 KOS16380.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KOS16380.1 - 0.0084 15.7 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KOS16380.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KOS16380.1 - 0.013 14.6 0.2 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KOS16380.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KOS16380.1 - 0.025 14.0 0.3 0.043 13.3 0.2 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_2 PF07724.9 KOS16380.1 - 0.044 13.6 1.0 0.26 11.1 0.0 2.7 3 1 0 3 3 2 0 AAA domain (Cdc48 subfamily) UPF0079 PF02367.12 KOS16380.1 - 0.051 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sipho_tail PF05709.6 KOS16380.1 - 0.059 12.4 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein AAA_28 PF13521.1 KOS16380.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KOS16380.1 - 0.075 12.8 2.1 0.2 11.4 0.5 2.3 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit Zot PF05707.7 KOS16380.1 - 0.076 12.4 0.0 4.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Parvo_NS1 PF01057.12 KOS16380.1 - 0.083 11.7 0.3 0.13 11.0 0.2 1.4 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 KOS16380.1 - 0.088 13.1 1.7 0.31 11.3 0.6 2.6 2 1 0 2 2 1 0 AAA domain cobW PF02492.14 KOS16380.1 - 0.094 12.1 1.3 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KOS16380.1 - 0.11 12.8 0.1 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KOS16380.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Prenyltrans PF00432.16 KOS16381.1 - 1.6e-30 104.2 16.9 2.6e-06 26.8 0.0 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KOS16381.1 - 2.6e-19 69.7 0.0 1e-14 54.9 0.0 3.8 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KOS16381.1 - 0.0032 17.4 0.0 0.14 12.2 0.0 2.9 1 1 2 3 3 3 3 Prenyltransferase-like RHD3 PF05879.7 KOS16382.1 - 3.8e-240 798.8 0.1 4.8e-240 798.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KOS16382.1 - 8e-06 25.0 0.1 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 KOS16382.1 - 1.6e-05 24.8 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KOS16382.1 - 4.1e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KOS16382.1 - 0.00058 20.3 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KOS16382.1 - 0.00061 19.7 0.2 0.0045 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2383 PF09537.5 KOS16382.1 - 0.066 13.4 3.1 0.39 10.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) MTHFR PF02219.12 KOS16383.1 - 5e-101 337.5 0.0 4.8e-100 334.3 0.0 2.0 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2204 PF09970.4 KOS16383.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) AFG1_ATPase PF03969.11 KOS16384.1 - 4.3e-85 285.6 0.1 1.7e-81 273.8 0.0 3.0 2 1 1 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 KOS16384.1 - 2e-05 24.6 0.0 7.3e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KOS16384.1 - 2.1e-05 24.6 0.0 0.00022 21.3 0.0 2.6 4 0 0 4 4 4 1 AAA domain zf-Mss51 PF13824.1 KOS16385.1 - 1.1e-21 76.4 0.9 2e-21 75.6 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Exo_endo_phos PF03372.18 KOS16386.1 - 2.2e-13 50.7 0.0 7.7e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DPBB_1 PF03330.13 KOS16387.1 - 1.2e-06 28.4 0.0 1.6e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KOS16387.1 - 0.0034 17.3 0.1 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Cerato-platanin AAA PF00004.24 KOS16388.1 - 4.1e-59 198.5 0.0 9.4e-45 152.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS16388.1 - 1.3e-06 28.5 8.4 0.011 15.6 0.1 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.9 KOS16388.1 - 3.1e-06 26.9 0.2 0.0054 16.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KOS16388.1 - 8.1e-06 25.0 0.2 0.0033 16.4 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KOS16388.1 - 2.1e-05 24.6 0.4 0.007 16.5 0.0 3.7 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KOS16388.1 - 0.00014 22.6 0.0 0.015 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KOS16388.1 - 0.00021 20.7 0.8 0.042 13.2 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 KOS16388.1 - 0.00027 20.6 0.4 0.002 17.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KOS16388.1 - 0.00053 19.6 1.0 0.99 9.0 0.0 3.2 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.12 KOS16388.1 - 0.00056 19.3 0.1 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KOS16388.1 - 0.0029 17.0 0.0 0.73 9.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain KaiC PF06745.8 KOS16388.1 - 0.0035 16.5 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 KaiC UPF0079 PF02367.12 KOS16388.1 - 0.0047 16.5 0.1 3.6 7.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_2 PF07724.9 KOS16388.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 KOS16388.1 - 0.0047 15.8 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KOS16388.1 - 0.005 16.4 0.0 0.5 9.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KOS16388.1 - 0.0055 16.5 0.0 0.15 11.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KOS16388.1 - 0.0064 16.6 0.0 0.086 13.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KOS16388.1 - 0.0074 15.4 0.2 0.037 13.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KOS16388.1 - 0.011 15.0 0.0 0.054 12.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KOS16388.1 - 0.011 15.3 0.3 0.026 14.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KOS16388.1 - 0.013 15.3 0.0 0.085 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KOS16388.1 - 0.013 15.5 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KOS16388.1 - 0.014 15.3 0.2 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KOS16388.1 - 0.017 14.0 0.0 0.74 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Vps4_C PF09336.5 KOS16388.1 - 0.02 14.7 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 KOS16388.1 - 0.022 13.5 0.1 0.076 11.7 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus Zeta_toxin PF06414.7 KOS16388.1 - 0.045 12.8 0.0 0.63 9.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KOS16388.1 - 0.081 13.2 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KOS16388.1 - 0.23 10.2 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain zf-HIT PF04438.11 KOS16389.1 - 5e-05 22.8 8.8 7.6e-05 22.2 6.1 1.3 1 0 0 1 1 1 1 HIT zinc finger AAA PF00004.24 KOS16390.1 - 5.2e-13 49.3 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KOS16390.1 - 2.2e-09 37.5 0.0 3.9e-08 33.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KOS16390.1 - 8.2e-07 29.2 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS16390.1 - 0.0048 16.6 1.3 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Cdc6_C PF09079.6 KOS16390.1 - 0.0087 15.7 0.0 0.027 14.1 0.0 1.9 1 1 0 1 1 1 1 CDC6, C terminal AAA_11 PF13086.1 KOS16390.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KOS16390.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Oxysterol_BP PF01237.13 KOS16391.1 - 2.9e-88 295.7 0.0 3.6e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein FNIP_N PF14636.1 KOS16391.1 - 0.47 10.9 3.6 0.18 12.3 0.8 1.5 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Beta_elim_lyase PF01212.16 KOS16392.1 - 7.8e-67 225.4 0.1 9.9e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KOS16392.1 - 0.00015 20.8 0.0 0.00037 19.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KOS16392.1 - 0.014 13.6 0.0 0.018 13.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KOS16392.1 - 0.032 13.2 0.1 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family CH PF00307.26 KOS16393.1 - 1.4e-65 218.1 0.2 4.6e-17 62.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KOS16393.1 - 5.4e-07 29.1 0.0 0.18 11.5 0.0 3.6 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_7 PF13499.1 KOS16393.1 - 0.00053 20.0 0.8 0.0039 17.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KOS16393.1 - 0.11 12.4 0.6 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DAHP_synth_2 PF01474.11 KOS16394.1 - 1.1e-178 594.1 0.0 1.2e-178 593.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family IGPS PF00218.16 KOS16395.1 - 6.4e-91 303.9 0.0 1.3e-90 302.8 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KOS16395.1 - 2.3e-48 164.3 0.0 7.8e-44 149.5 0.0 2.3 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KOS16395.1 - 9.3e-47 158.9 0.1 1.6e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KOS16395.1 - 6.1e-06 25.8 0.0 1.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KOS16395.1 - 0.003 17.1 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Methyltransf_4 PF02390.12 KOS16396.1 - 3.8e-54 182.7 0.0 1.2e-40 138.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KOS16396.1 - 0.0002 21.9 0.0 0.0014 19.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KOS16396.1 - 0.003 17.8 0.0 0.0099 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16396.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KOS16396.1 - 0.0039 17.2 0.0 0.0081 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KOS16396.1 - 0.015 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 KOS16396.1 - 0.02 14.4 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KOS16396.1 - 0.06 12.7 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KOS16396.1 - 0.11 12.2 0.0 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KOS16396.1 - 0.15 12.5 0.0 10 6.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain SPT16 PF08644.6 KOS16397.1 - 6.7e-52 175.3 3.2 7.3e-52 175.2 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 KOS16397.1 - 9.2e-20 70.4 0.0 2.4e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Snurportin1 PF11538.3 KOS16397.1 - 3.3 7.5 10.0 4.4 7.1 0.7 2.7 2 0 0 2 2 2 0 Snurportin1 PGM_PMM_I PF02878.11 KOS16398.1 - 2.3e-20 72.4 0.0 1.9e-09 37.1 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KOS16398.1 - 5.5e-14 52.3 0.0 2.9e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KOS16398.1 - 1.1e-10 41.3 0.1 3.1e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KOS16398.1 - 0.0011 19.0 0.1 0.0026 17.7 0.1 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Adenylsucc_synt PF00709.16 KOS16399.1 - 8.4e-160 532.0 0.0 9.5e-160 531.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase RTC PF01137.16 KOS16400.1 - 1.1e-59 201.0 0.0 1.4e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KOS16400.1 - 4.8e-31 106.8 0.0 7.9e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain COX4 PF02936.9 KOS16401.1 - 8.5e-33 113.0 0.3 1.9e-32 111.9 0.1 1.5 1 1 1 2 2 2 1 Cytochrome c oxidase subunit IV Proteasome PF00227.21 KOS16402.1 - 3.4e-47 160.1 0.3 1.6e-45 154.7 0.2 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KOS16402.1 - 2.8e-15 55.2 0.1 4.7e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PC_rep PF01851.17 KOS16403.1 - 2.7e-43 143.7 24.1 3.8e-09 36.2 0.1 11.6 12 0 0 12 12 12 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KOS16403.1 - 1.1e-18 67.2 6.2 4.4e-10 39.7 0.0 5.0 3 1 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KOS16403.1 - 2.1e-07 31.1 10.5 0.012 16.1 0.2 6.0 7 0 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KOS16403.1 - 1.6e-06 27.6 2.1 9.3 6.6 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat Apc3 PF12895.2 KOS16403.1 - 0.014 15.4 0.3 0.61 10.2 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3602 PF12223.3 KOS16403.1 - 0.091 13.1 0.7 15 6.0 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) Telomere_reg-2 PF10193.4 KOS16403.1 - 0.11 12.7 1.7 1.8 8.8 0.1 3.1 3 0 0 3 3 3 0 Telomere length regulation protein HEAT_PBS PF03130.11 KOS16403.1 - 0.13 12.8 6.0 33 5.3 0.0 4.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Nop PF01798.13 KOS16404.1 - 1.5e-39 134.6 0.1 2.6e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 KOS16404.1 - 2.6e-39 134.4 1.8 4.9e-39 133.5 1.2 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 KOS16404.1 - 2.3e-16 59.3 0.0 5.6e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain Ribosomal_S3_C PF00189.15 KOS16404.1 - 0.02 15.0 0.2 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein S3, C-terminal domain Aminotran_1_2 PF00155.16 KOS16405.1 - 7.4e-48 163.3 0.0 1e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KOS16405.1 - 7.8e-05 21.1 0.0 0.00013 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KOS16405.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.16 KOS16405.1 - 0.1 11.4 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-III Clp1 PF06807.9 KOS16406.1 - 5.1e-06 26.3 0.0 3.2e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KOS16406.1 - 7e-06 25.7 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CPT PF07931.7 KOS16406.1 - 0.1 12.2 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PPR_3 PF13812.1 KOS16407.1 - 0.00034 20.6 2.5 0.4 11.0 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KOS16407.1 - 0.0017 18.2 0.0 0.011 15.7 0.0 2.3 3 0 0 3 3 3 1 PPR repeat family MIF4G_like PF09088.6 KOS16408.1 - 1.5e-58 197.4 0.0 4.2e-58 195.9 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 KOS16408.1 - 7.2e-36 123.6 0.0 1e-26 93.7 0.0 2.2 2 0 0 2 2 2 2 MIF4G like AAA PF00004.24 KOS16409.1 - 2.2e-05 24.6 0.0 4.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KOS16409.1 - 0.032 14.3 0.2 0.23 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.9 KOS16409.1 - 0.09 10.5 0.0 0.13 10.0 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.1 KOS16409.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 KOS16409.1 - 0.14 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Fe_hyd_lg_C PF02906.9 KOS16410.1 - 4.3e-68 229.6 0.0 7.2e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peroxin-3 PF04882.7 KOS16411.1 - 9.6e-100 334.2 0.0 1.1e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 MCPVI PF02993.9 KOS16411.1 - 0.53 10.4 4.6 0.85 9.7 3.2 1.3 1 0 0 1 1 1 0 Minor capsid protein VI CwfJ_C_1 PF04677.10 KOS16412.1 - 1.4e-30 105.4 0.0 2.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KOS16412.1 - 4.6e-07 30.2 0.0 7.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 WD40 PF00400.27 KOS16413.1 - 1.1e-09 37.8 2.3 0.00011 21.9 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat TAF4 PF05236.9 KOS16414.1 - 6.8e-26 91.1 1.4 6.7e-25 87.8 1.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Macoilin PF09726.4 KOS16414.1 - 5.5 5.1 8.1 7.7 4.6 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein HLH PF00010.21 KOS16415.1 - 2.5e-13 49.4 0.0 5.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF342 PF03961.8 KOS16415.1 - 0.17 10.2 0.1 0.24 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UBX PF00789.15 KOS16416.1 - 1.3e-17 63.6 0.0 3.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KOS16416.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like RibD_C PF01872.12 KOS16417.1 - 3.7e-30 105.0 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DUF1771 PF08590.5 KOS16418.1 - 1.2e-17 63.6 10.0 1.2e-17 63.6 6.9 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1771) Smr PF01713.16 KOS16418.1 - 1.3e-14 54.0 0.3 1.3e-14 54.0 0.2 2.3 2 0 0 2 2 2 1 Smr domain Helicase_C PF00271.26 KOS16418.1 - 1.8e-12 46.9 0.0 4.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KOS16418.1 - 7.4e-05 22.3 0.0 0.00021 20.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KOS16418.1 - 0.001 18.9 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KOS16418.1 - 0.044 12.5 0.1 0.39 9.4 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain Actin PF00022.14 KOS16419.1 - 3.6e-130 433.9 0.0 4e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Actin 6PF2K PF01591.13 KOS16420.1 - 8.4e-60 201.6 0.0 1.3e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KOS16420.1 - 1.1e-19 71.1 0.3 3.5e-19 69.4 0.1 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KOS16420.1 - 2.6e-08 33.8 0.5 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KOS16420.1 - 0.00019 21.1 0.1 0.00093 18.8 0.1 2.0 1 1 0 1 1 1 1 Adenylylsulphate kinase CPT PF07931.7 KOS16420.1 - 0.00037 20.1 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 KOS16420.1 - 0.0037 16.3 0.0 0.019 14.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 KOS16420.1 - 0.0051 16.0 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KOS16420.1 - 0.028 15.2 0.4 0.18 12.6 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KOS16420.1 - 0.032 14.4 0.1 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KOS16420.1 - 0.12 12.1 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain HEAT_2 PF13646.1 KOS16421.1 - 7.5e-39 131.9 2.3 1e-13 51.3 0.0 3.6 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 KOS16421.1 - 5.3e-13 48.1 0.4 0.014 15.7 0.0 6.9 7 0 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT PF02985.17 KOS16421.1 - 9.9e-12 43.9 2.0 0.38 10.9 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KOS16421.1 - 1e-11 44.9 0.3 0.15 12.5 0.1 5.3 5 0 0 5 5 5 3 HEAT-like repeat Arm PF00514.18 KOS16421.1 - 0.023 14.5 1.0 13 5.8 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UPF0147 PF03685.8 KOS16421.1 - 0.045 13.6 0.1 0.55 10.1 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) DWNN PF08783.6 KOS16422.1 - 3.9e-32 110.0 0.0 7.4e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KOS16422.1 - 2e-06 27.1 5.9 9.5e-06 25.0 4.1 2.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KOS16422.1 - 8e-06 25.5 2.0 1.6e-05 24.5 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 KOS16422.1 - 0.00018 21.4 14.8 0.00018 21.4 10.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 KOS16422.1 - 0.0026 17.4 0.3 0.0026 17.4 0.2 2.0 2 0 0 2 2 1 1 Zinc knuckle zf-C3HC4_3 PF13920.1 KOS16422.1 - 0.0034 17.0 10.5 0.0034 17.0 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KOS16422.1 - 0.0049 16.5 14.7 0.0049 16.5 10.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KOS16422.1 - 0.0096 15.5 15.9 0.02 14.5 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KOS16422.1 - 0.017 14.9 14.5 0.017 14.9 10.0 1.7 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 KOS16422.1 - 0.042 13.7 14.3 0.091 12.6 9.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KOS16422.1 - 0.14 11.9 8.0 0.023 14.4 2.8 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Hamartin PF04388.7 KOS16422.1 - 0.29 9.7 10.5 0.52 8.9 0.4 2.2 2 0 0 2 2 2 0 Hamartin protein zf-CCHC_5 PF14787.1 KOS16422.1 - 0.49 9.9 4.6 0.25 10.8 0.6 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Zn_Tnp_IS1595 PF12760.2 KOS16422.1 - 0.59 9.9 8.3 0.79 9.5 0.1 2.8 3 0 0 3 3 2 0 Transposase zinc-ribbon domain Gin PF10764.4 KOS16422.1 - 1.2 8.9 6.2 1 9.1 1.2 2.6 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF1272 PF06906.6 KOS16422.1 - 1.8 8.5 10.3 4.3 7.2 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Trm112p PF03966.11 KOS16422.1 - 7.1 7.0 7.7 8.8 6.7 4.2 2.0 2 0 0 2 2 1 0 Trm112p-like protein MGC-24 PF05283.6 KOS16422.1 - 9.5 5.9 24.9 0.073 12.8 8.1 3.1 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24) DUF3591 PF12157.3 KOS16423.1 - 1.9e-183 610.0 0.3 3e-183 609.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KOS16423.1 - 1.8e-05 24.2 1.9 4.4e-05 23.0 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Med16 PF11635.3 KOS16423.1 - 0.049 11.6 0.1 0.07 11.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Cys_Met_Meta_PP PF01053.15 KOS16424.1 - 4e-49 166.9 0.0 1.1e-40 139.1 0.0 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KOS16424.1 - 0.012 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KOS16424.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II eIF-5_eIF-2B PF01873.12 KOS16425.1 - 7.5e-42 141.9 0.0 1.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KOS16425.1 - 4.5e-26 90.6 2.5 2e-25 88.5 1.7 2.2 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_RNApol_7kD PF03604.8 KOS16425.1 - 0.14 11.6 3.3 0.26 10.8 2.3 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Sporozoite_P67 PF05642.6 KOS16425.1 - 1.1 7.0 5.2 2.1 6.1 3.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.9 KOS16425.1 - 1.7 8.1 11.7 3 7.3 3.6 2.5 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 KOS16425.1 - 5.1 6.6 21.3 7.8 6.0 6.0 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region Mo25 PF08569.6 KOS16426.1 - 1.2e-100 336.7 3.2 1.5e-100 336.5 2.2 1.0 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.9 KOS16426.1 - 0.0015 17.7 0.9 0.0015 17.7 0.7 1.6 2 0 0 2 2 2 1 V-ATPase subunit H Nic96 PF04097.9 KOS16427.1 - 1.2e-162 542.2 0.2 1.6e-162 541.7 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 CBS PF00571.23 KOS16428.1 - 8.9e-15 54.2 7.1 4.6e-06 26.3 0.0 5.5 5 0 0 5 5 5 5 CBS domain TRAPP PF04051.11 KOS16429.1 - 2.4e-31 108.3 0.0 2.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Atg14 PF10186.4 KOS16430.1 - 6.6e-16 58.1 0.7 1.2e-15 57.2 0.5 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FTA4 PF13093.1 KOS16430.1 - 0.51 9.7 5.7 0.9 8.9 3.9 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4201 PF13870.1 KOS16430.1 - 2 7.7 9.9 0.63 9.4 4.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AMP-binding PF00501.23 KOS16431.1 - 2.9e-91 305.9 0.0 3.7e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS16431.1 - 1.4e-10 41.9 0.0 6e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain tRNA-synt_2b PF00587.20 KOS16432.1 - 2.9e-41 140.9 0.0 4.6e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KOS16432.1 - 6.8e-08 32.3 0.0 6.7e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 KOS16432.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase CDC45 PF02724.9 KOS16433.1 - 1e-186 621.7 0.0 1.1e-186 621.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein His_biosynth PF00977.16 KOS16434.1 - 1.8e-27 96.0 0.0 2.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein IATP PF04568.7 KOS16435.1 - 3.4e-14 52.6 0.4 4.1e-14 52.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF4055 PF13264.1 KOS16435.1 - 0.022 14.8 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) zf-CHC2 PF01807.15 KOS16436.1 - 0.0046 16.4 0.2 0.0067 15.9 0.1 1.3 1 0 0 1 1 1 1 CHC2 zinc finger AAA_11 PF13086.1 KOS16437.1 - 6.1e-50 169.9 0.1 1.1e-49 169.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KOS16437.1 - 3.8e-46 156.9 0.0 7.3e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KOS16437.1 - 1.1e-13 50.6 4.2 1.4e-11 43.9 1.1 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 KOS16437.1 - 6.7e-11 42.1 0.1 1.2e-08 34.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KOS16437.1 - 0.0025 17.1 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KOS16437.1 - 0.029 14.5 0.8 3.8 7.6 0.1 3.2 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KOS16437.1 - 0.046 13.2 0.2 17 4.7 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FliD_N PF02465.13 KOS16438.1 - 0.051 13.9 0.9 0.065 13.6 0.0 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1289 PF06945.8 KOS16438.1 - 0.059 12.8 0.2 0.095 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Cyclase PF04199.8 KOS16439.1 - 0.002 17.8 0.4 0.0038 16.9 0.3 1.5 1 0 0 1 1 1 1 Putative cyclase Nol1_Nop2_Fmu PF01189.12 KOS16440.1 - 1.8e-18 66.9 0.7 3.4e-17 62.7 0.0 2.7 2 1 0 2 2 2 1 NOL1/NOP2/sun family GMC_oxred_N PF00732.14 KOS16443.1 - 6.1e-36 124.0 0.1 3e-35 121.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KOS16443.1 - 3.2e-24 85.8 0.3 9.2e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KOS16443.1 - 5.3e-10 38.7 3.1 2.2e-05 23.4 1.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KOS16443.1 - 6.7e-06 25.2 10.7 0.006 15.5 3.6 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KOS16443.1 - 0.00036 19.6 2.1 0.00076 18.6 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KOS16443.1 - 0.00054 19.9 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KOS16443.1 - 0.0007 18.7 0.8 0.0014 17.7 0.5 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KOS16443.1 - 0.0027 17.6 2.2 0.0066 16.4 1.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KOS16443.1 - 0.07 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KOS16443.1 - 0.088 12.8 2.4 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KOS16443.1 - 0.11 12.9 0.9 0.43 11.0 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KOS16443.1 - 0.26 9.5 0.0 0.39 8.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.9 KOS16443.1 - 0.43 8.9 3.2 1.3 7.4 1.5 1.9 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KOS16443.1 - 0.66 9.3 2.9 1.2 8.5 2.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PPR_2 PF13041.1 KOS16444.1 - 8e-08 32.1 0.0 0.00012 21.9 0.0 4.0 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.1 KOS16444.1 - 0.00016 21.6 3.8 0.025 14.8 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Ribosomal_L11_N PF03946.9 KOS16444.1 - 0.0034 16.8 0.0 0.055 12.9 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain PPR PF01535.15 KOS16444.1 - 0.0051 16.7 0.6 10 6.3 0.0 4.9 6 0 0 6 6 6 1 PPR repeat Pyridox_oxase_2 PF12766.2 KOS16445.1 - 4.4e-17 62.2 0.0 8.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF543 PF04418.7 KOS16446.1 - 0.066 13.1 3.0 0.081 12.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ThiW PF09512.5 KOS16446.1 - 0.32 10.8 5.3 0.37 10.6 2.4 1.8 1 1 1 2 2 2 0 Thiamine-precursor transporter protein (ThiW) NTF2 PF02136.15 KOS16447.1 - 2.9e-08 34.0 1.1 7.7e-07 29.5 0.0 2.8 1 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KOS16447.1 - 3e-07 30.3 0.0 6.4e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 Collagen_bind_2 PF12904.2 KOS16447.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Sec5 PF15469.1 KOS16448.1 - 2.7e-50 170.6 0.0 5.6e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 KOS16448.1 - 0.0001 22.0 0.0 0.00036 20.3 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KOS16448.1 - 0.012 15.5 0.1 0.061 13.1 0.0 2.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pep3_Vps18 PF05131.9 KOS16449.1 - 9.7e-26 89.9 0.2 7.2e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KOS16449.1 - 0.00036 20.1 0.9 0.034 13.7 0.1 2.6 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 KOS16449.1 - 0.00079 19.5 0.1 0.017 15.2 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_11 PF13414.1 KOS16449.1 - 0.00081 18.9 3.6 0.2 11.3 0.6 3.2 2 0 0 2 2 2 2 TPR repeat zf-RING_2 PF13639.1 KOS16449.1 - 0.0045 16.7 4.5 0.041 13.7 0.9 3.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KOS16449.1 - 0.015 15.3 1.4 0.026 14.6 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger TPR_17 PF13431.1 KOS16449.1 - 0.036 14.2 0.7 0.92 9.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1664 PF07889.7 KOS16449.1 - 0.054 13.3 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_8 PF13181.1 KOS16449.1 - 0.14 12.0 0.5 1.2 9.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_5 PF14634.1 KOS16449.1 - 0.35 10.6 5.2 0.11 12.2 0.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-Apc11 PF12861.2 KOS16449.1 - 0.55 10.1 4.0 0.38 10.6 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FA_desaturase PF00487.19 KOS16450.1 - 9.3e-23 80.9 14.9 9.3e-23 80.9 10.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KOS16450.1 - 2.4e-18 65.0 0.2 4.5e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ank_2 PF12796.2 KOS16451.1 - 1e-44 150.7 5.6 2.1e-14 53.6 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KOS16451.1 - 1.4e-41 138.2 13.7 3.8e-09 35.9 0.1 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KOS16451.1 - 3.4e-37 126.1 11.8 2.9e-12 46.7 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS16451.1 - 7.2e-32 108.6 18.6 1.3e-10 41.1 0.5 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) zf-DHHC PF01529.15 KOS16451.1 - 2e-30 105.4 7.2 2e-30 105.4 5.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.1 KOS16451.1 - 3.2e-27 91.8 9.1 2.6e-06 27.1 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KOS16452.1 - 1.8e-09 37.7 0.2 1.6e-08 34.7 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KOS16452.1 - 2.9e-07 29.9 1.4 0.021 14.6 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KOS16452.1 - 5.1e-06 26.5 0.6 0.0035 17.5 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KOS16452.1 - 5.3e-05 23.6 0.4 0.00023 21.5 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS16452.1 - 0.00017 21.5 0.4 8.6 6.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ebola_NP PF05505.7 KOS16453.1 - 0.82 7.6 12.6 0.94 7.4 8.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIE-A_C-term PF11521.3 KOS16453.1 - 5.2 7.0 17.9 0.13 12.1 1.4 2.3 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ldh_1_N PF00056.18 KOS16454.1 - 2.7e-41 140.6 0.0 4.2e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KOS16454.1 - 1.4e-39 135.6 0.1 2.5e-39 134.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KOS16454.1 - 0.00054 18.7 0.0 0.00076 18.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KOS16454.1 - 0.079 12.2 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase cobW PF02492.14 KOS16455.1 - 6.6e-36 123.4 0.0 8.2e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KOS16455.1 - 6.2e-07 28.4 1.5 2.8e-06 26.3 1.0 1.8 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KOS16455.1 - 0.00032 20.6 0.0 0.0012 18.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KOS16455.1 - 0.00089 20.0 0.0 0.0015 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.7 KOS16455.1 - 0.0061 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_18 PF13238.1 KOS16455.1 - 0.0088 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KOS16455.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KOS16455.1 - 0.02 15.2 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KOS16455.1 - 0.022 14.2 0.1 6.4 6.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.9 KOS16455.1 - 0.026 13.4 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 KOS16455.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase CbiA PF01656.18 KOS16455.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.8 KOS16455.1 - 0.051 12.2 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 KOS16455.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 KOS16455.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KOS16455.1 - 0.075 13.0 0.1 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 KOS16455.1 - 0.077 11.9 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KOS16455.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 KOS16455.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 KOS16455.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein NACHT PF05729.7 KOS16455.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SelP_N PF04592.9 KOS16455.1 - 9.4 5.5 9.9 15 4.9 6.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PI3_PI4_kinase PF00454.22 KOS16456.1 - 3.5e-35 121.5 0.0 7.3e-34 117.2 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KOS16456.1 - 1.1e-20 73.6 0.1 3.7e-20 71.8 0.0 1.9 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PLDc_2 PF13091.1 KOS16457.1 - 3.4e-16 59.1 0.0 8.6e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain STT3 PF02516.9 KOS16458.1 - 3e-126 422.2 38.9 5.8e-126 421.2 26.9 1.4 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Pkinase PF00069.20 KOS16459.1 - 1e-70 237.8 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16459.1 - 7.9e-39 133.2 0.0 1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KOS16459.1 - 1.3e-07 30.9 0.0 1.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KOS16459.1 - 0.0001 21.4 0.2 0.00046 19.3 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KOS16459.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KOS16459.1 - 0.047 13.4 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KOS16459.1 - 0.098 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hat1_N PF10394.4 KOS16460.1 - 2.3e-34 118.7 0.0 4.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 KOS16460.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KOS16460.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KOS16460.1 - 0.029 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain V-SNARE_C PF12352.3 KOS16461.1 - 5.1e-14 52.0 2.3 5.1e-14 52.0 1.6 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Ank_2 PF12796.2 KOS16462.1 - 7.1e-48 160.8 15.3 2.7e-16 59.6 0.3 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) SPX PF03105.14 KOS16462.1 - 1.1e-33 117.1 1.9 7.7e-20 71.8 0.0 2.3 2 0 0 2 2 2 2 SPX domain Ank PF00023.25 KOS16462.1 - 1.1e-32 110.2 9.0 1.5e-06 27.7 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KOS16462.1 - 2.7e-31 107.3 10.3 7.3e-09 35.9 0.2 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KOS16462.1 - 3.6e-25 87.4 9.3 0.00015 21.8 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KOS16462.1 - 6.9e-22 75.3 8.9 0.0033 17.5 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat GDPD PF03009.12 KOS16462.1 - 3.8e-12 46.2 0.0 7.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family AcetylCoA_hydro PF02550.10 KOS16462.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Nop PF01798.13 KOS16463.1 - 5.6e-60 200.9 0.1 1.5e-59 199.6 0.0 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KOS16463.1 - 2.3e-26 91.3 0.2 5.7e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KOS16463.1 - 6e-21 74.3 0.1 6e-21 74.3 0.1 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain BCDHK_Adom3 PF10436.4 KOS16463.1 - 0.037 13.5 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Na_trans_assoc PF06512.8 KOS16463.1 - 0.67 9.8 13.2 1.1 9.2 9.2 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated GAGA_bind PF06217.7 KOS16463.1 - 3.3 7.6 12.4 5.1 6.9 8.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Glu_synthase PF01645.12 KOS16464.1 - 1.9e-159 530.5 0.0 2.8e-159 529.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KOS16464.1 - 1.7e-129 431.6 0.0 2.4e-129 431.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KOS16464.1 - 5e-116 387.0 0.0 8.5e-116 386.2 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KOS16464.1 - 8.3e-65 217.5 1.7 1.6e-64 216.6 1.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KOS16464.1 - 8.1e-23 80.1 0.1 1.8e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KOS16464.1 - 6.5e-18 65.3 0.0 1.7e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KOS16464.1 - 2.9e-11 43.8 0.3 0.0003 20.9 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KOS16464.1 - 3.2e-09 36.6 0.1 1.3e-08 34.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KOS16464.1 - 9.1e-08 32.4 0.8 4.5e-05 23.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KOS16464.1 - 4.8e-07 29.1 0.1 8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KOS16464.1 - 5.7e-06 25.4 1.9 5.3e-05 22.2 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KOS16464.1 - 7.8e-06 24.9 0.5 0.00024 20.0 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KOS16464.1 - 1.8e-05 23.3 0.2 1.8e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KOS16464.1 - 0.00012 21.3 0.7 0.00021 20.4 0.1 1.7 2 0 0 2 2 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KOS16464.1 - 0.0011 19.2 0.4 0.71 10.1 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KOS16464.1 - 0.0019 17.3 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KOS16464.1 - 0.012 14.7 0.1 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AdoHcyase_NAD PF00670.16 KOS16464.1 - 0.013 15.3 4.3 1.3 8.8 0.0 2.8 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KOS16464.1 - 0.025 13.7 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.13 KOS16464.1 - 0.025 13.4 0.4 0.15 10.8 0.2 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.18 KOS16464.1 - 0.027 14.1 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KOS16464.1 - 0.043 13.3 0.9 0.45 10.0 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KOS16464.1 - 0.17 12.0 0.4 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 KOS16464.1 - 0.24 9.5 0.6 1.7 6.7 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.17 KOS16464.1 - 0.5 9.1 4.0 0.17 10.7 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KOS16464.1 - 7.3 6.1 5.7 0.6 9.7 0.2 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KOS16464.1 - 9.3 6.2 7.2 3.7 7.5 0.1 2.8 3 0 0 3 3 2 0 NADH(P)-binding UQ_con PF00179.21 KOS16465.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme MRP-L46 PF11788.3 KOS16466.1 - 2.6e-17 63.4 0.6 4.8e-17 62.6 0.4 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Rsa3 PF14615.1 KOS16467.1 - 2.2e-09 36.4 0.3 1.5e-06 27.3 0.1 2.3 2 0 0 2 2 2 2 Ribosome-assembly protein 3 SURF2 PF05477.6 KOS16467.1 - 1.6 7.8 5.2 2 7.4 3.6 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Usp PF00582.21 KOS16468.1 - 2.3e-18 66.7 0.0 3.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Mak10 PF04112.8 KOS16469.1 - 7.7e-28 96.8 0.0 1.3e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1 PF00133.17 KOS16470.1 - 2.3e-151 504.7 0.0 3e-151 504.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KOS16470.1 - 1.5e-23 83.2 0.0 2.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KOS16470.1 - 2.7e-23 82.2 0.0 1.1e-14 53.9 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 KOS16470.1 - 0.00025 20.5 3.8 0.00054 19.5 2.6 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KOS16470.1 - 0.002 17.4 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KOS16470.1 - 0.0075 15.4 0.0 0.94 8.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KOS16470.1 - 0.13 10.9 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) Per1 PF04080.8 KOS16471.1 - 9.7e-74 248.1 4.8 1.3e-73 247.7 3.3 1.1 1 0 0 1 1 1 1 Per1-like CBS PF00571.23 KOS16471.1 - 0.078 12.7 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 CBS domain Nucleoporin_FG PF13634.1 KOS16472.1 - 4.7e-21 75.1 115.1 4.2e-11 43.0 29.9 3.8 1 1 2 3 3 3 3 Nucleoporin FG repeat region RepB PF07506.6 KOS16472.1 - 0.021 14.6 1.8 0.04 13.7 1.2 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein Sarcoglycan_2 PF05510.8 KOS16472.1 - 0.19 9.9 4.1 0.091 11.0 0.8 1.8 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Mnd1 PF03962.10 KOS16472.1 - 1.6 8.3 9.1 0.61 9.7 3.4 1.9 1 1 1 2 2 2 0 Mnd1 family DivIC PF04977.10 KOS16472.1 - 2.9 7.4 4.8 4.1 6.9 0.0 2.9 2 2 1 3 3 3 0 Septum formation initiator Cluap1 PF10234.4 KOS16472.1 - 4.9 6.2 10.3 1 8.5 3.7 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 SNO PF01174.14 KOS16473.1 - 1.1e-47 162.1 0.0 4.2e-37 127.5 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KOS16473.1 - 7e-08 32.2 0.1 1.7e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KOS16473.1 - 0.00048 19.6 0.1 0.0039 16.6 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 KOS16473.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 KOS16473.1 - 0.012 15.0 0.2 0.13 11.6 0.1 2.3 1 1 0 1 1 1 0 Peptidase C26 DJ-1_PfpI PF01965.19 KOS16473.1 - 0.03 13.7 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family DEAD PF00270.24 KOS16474.1 - 5.4e-42 143.1 0.0 5e-41 140.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16474.1 - 3.8e-27 93.9 0.0 6.6e-26 89.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KOS16474.1 - 0.0019 18.0 6.9 0.002 18.0 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KOS16474.1 - 0.004 16.2 0.0 0.004 16.2 0.0 2.7 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit IFT46_B_C PF12317.3 KOS16474.1 - 0.012 14.9 0.0 0.012 14.9 0.0 2.2 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Lipase_2 PF01674.13 KOS16474.1 - 0.042 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) DUF1253 PF06862.7 KOS16474.1 - 0.5 8.7 0.0 0.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Ndc1_Nup PF09531.5 KOS16474.1 - 1.1 7.5 5.0 1.5 7.1 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_polI_A34 PF08208.6 KOS16474.1 - 1.3 8.6 32.6 2.4 7.7 22.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Aminotran_4 PF01063.14 KOS16475.1 - 1.2e-26 93.6 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Ribosomal_L6 PF00347.18 KOS16476.1 - 2.3e-26 92.0 1.4 1.6e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Epimerase PF01370.16 KOS16477.1 - 2.7e-09 36.8 0.0 4.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KOS16477.1 - 4.1e-09 36.6 0.1 9.9e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KOS16477.1 - 0.0036 17.2 0.1 0.0095 15.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KOS16477.1 - 0.016 14.0 0.0 0.15 10.9 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KOS16477.1 - 0.02 13.6 0.0 0.079 11.6 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KOS16477.1 - 0.057 12.3 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein AlaDh_PNT_C PF01262.16 KOS16477.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 KOS16477.1 - 0.15 11.2 0.1 2.8 7.1 0.3 2.5 3 0 0 3 3 3 0 NmrA-like family SNF2_N PF00176.18 KOS16478.1 - 2.4e-69 233.4 0.5 5.6e-69 232.2 0.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KOS16478.1 - 3.2e-16 58.9 0.3 9.5e-16 57.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 KOS16478.1 - 4.9e-09 35.8 11.1 4.9e-09 35.8 7.7 3.7 3 1 1 4 4 4 1 HSA RNase_H2_suC PF08615.6 KOS16478.1 - 2 8.2 10.9 11 5.9 5.1 2.9 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MAM33 PF02330.11 KOS16479.1 - 4.8e-35 121.1 0.0 5.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ribosomal_L7Ae PF01248.21 KOS16480.1 - 8.8e-24 82.8 0.0 1e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 KOS16480.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Rieske PF00355.21 KOS16481.1 - 4.7e-18 64.5 0.0 8.1e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 KOS16481.1 - 1.3e-15 57.3 2.6 2.9e-15 56.2 1.8 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region RRM_1 PF00076.17 KOS16482.1 - 2.2e-21 75.2 0.0 2e-09 36.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16482.1 - 7.3e-20 70.7 0.0 6.6e-10 38.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16482.1 - 2.2e-05 24.2 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 KOS16483.1 - 1.4e-20 72.8 0.5 2.3e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 KOS16483.1 - 4.2e-09 35.9 0.1 2e-08 33.7 0.1 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16483.1 - 5.8e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16483.1 - 0.00029 20.6 0.1 0.0007 19.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS16483.1 - 0.0081 15.9 0.1 0.087 12.6 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif Eaf7 PF07904.8 KOS16484.1 - 1.1e-17 63.7 0.0 2.3e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Abhydrolase_3 PF07859.8 KOS16485.1 - 1.7e-27 96.3 0.0 2.4e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KOS16485.1 - 6.8e-06 26.1 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KOS16485.1 - 0.00065 19.4 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KOS16485.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KOS16485.1 - 0.0015 18.0 0.0 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KOS16485.1 - 0.002 17.3 0.0 0.031 13.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KOS16485.1 - 0.0029 16.9 0.0 0.0091 15.2 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.15 KOS16485.1 - 0.0096 16.1 0.0 0.025 14.8 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain zf-RNPHF PF08080.7 KOS16485.1 - 0.07 12.6 0.7 0.21 11.1 0.1 2.0 2 0 0 2 2 2 0 RNPHF zinc finger PITH PF06201.8 KOS16486.1 - 3.4e-26 91.8 0.0 6.4e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 PITH domain Abhydrolase_3 PF07859.8 KOS16487.1 - 4.5e-35 121.1 0.0 5.8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS16487.1 - 4.5e-05 22.7 0.0 0.0017 17.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KOS16487.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS16487.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KOS16487.1 - 0.0023 16.4 0.0 0.0041 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KOS16487.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SH3_1 PF00018.23 KOS16488.1 - 3.6e-08 32.6 0.0 5.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS16488.1 - 2.2e-05 23.9 0.3 3.6e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KOS16488.1 - 0.058 12.8 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain VMA21 PF09446.5 KOS16490.1 - 1.2e-08 34.6 5.9 2.5e-08 33.6 4.1 1.5 1 1 0 1 1 1 1 VMA21-like domain DUF2638 PF10937.3 KOS16491.1 - 3.9e-15 56.8 1.3 4.5e-15 56.6 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) SR-25 PF10500.4 KOS16491.1 - 0.021 14.3 8.8 0.024 14.1 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KOS16491.1 - 7.2 6.6 15.2 10 6.1 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SMC_N PF02463.14 KOS16492.1 - 2.6e-26 92.2 0.0 6.8e-26 90.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KOS16492.1 - 8.8e-11 42.5 27.6 8.8e-11 42.5 19.2 4.5 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KOS16492.1 - 4e-06 26.1 1.6 6.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KOS16492.1 - 9.7e-06 25.7 0.2 0.0023 17.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KOS16492.1 - 2.3e-05 23.8 0.1 6.1e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 KOS16492.1 - 0.0011 18.9 0.1 0.02 14.8 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 KOS16492.1 - 2 8.7 23.1 20 5.4 0.0 5.0 2 2 2 4 4 4 0 ABC transporter IL11 PF07400.6 KOS16492.1 - 3.1 7.2 5.5 2.5 7.5 0.8 2.7 3 0 0 3 3 3 0 Interleukin 11 PPTA PF01239.17 KOS16493.1 - 3.6e-05 22.9 0.0 8e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Protein prenyltransferase alpha subunit repeat GSHPx PF00255.14 KOS16494.1 - 1e-39 134.2 0.2 1.3e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KOS16494.1 - 4.9e-05 23.0 0.0 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KOS16494.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 KOS16494.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) SCO1-SenC PF02630.9 KOS16494.1 - 0.078 12.5 0.1 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 SCO1/SenC Na_H_Exchanger PF00999.16 KOS16495.1 - 8.5e-53 179.2 18.5 1e-52 178.9 12.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KOS16495.1 - 0.00052 19.9 1.2 0.01 15.7 0.0 3.1 3 0 0 3 3 3 1 YrhC-like protein Methyltransf_PK PF05891.7 KOS16496.1 - 8.6e-52 175.5 0.1 8.8e-26 90.5 0.0 3.3 2 2 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 KOS16496.1 - 0.00012 22.3 0.0 0.002 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KOS16496.1 - 0.00018 21.2 0.0 0.0014 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KOS16496.1 - 0.00022 21.6 0.0 0.017 15.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KOS16496.1 - 0.0008 19.8 0.0 0.024 15.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KOS16496.1 - 0.0013 19.3 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KOS16496.1 - 0.17 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Abhydrolase_6 PF12697.2 KOS16497.1 - 5.8e-30 104.8 0.6 7.3e-30 104.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KOS16497.1 - 7.1e-21 74.8 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KOS16497.1 - 1.8e-12 47.1 0.0 3.2e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KOS16497.1 - 8.9e-05 22.0 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KOS16497.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KOS16497.1 - 0.00053 19.2 0.4 0.015 14.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KOS16497.1 - 0.0011 18.3 0.3 1.4 8.1 0.2 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family PGAP1 PF07819.8 KOS16497.1 - 0.0026 17.4 0.0 0.0097 15.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 KOS16497.1 - 0.0042 17.3 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KOS16497.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF1100 PF06500.6 KOS16497.1 - 0.017 13.7 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 KOS16497.1 - 0.063 12.6 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PPTA PF01239.17 KOS16498.1 - 8.6e-33 110.3 6.6 2.8e-11 42.2 0.0 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 KOS16498.1 - 0.63 9.5 7.7 25 4.4 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) OTCace PF00185.19 KOS16499.1 - 5.8e-43 146.4 0.0 9.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KOS16499.1 - 7.6e-43 145.5 0.1 1.1e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RRM_1 PF00076.17 KOS16500.1 - 9.1e-28 95.6 0.0 3.5e-16 58.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16500.1 - 6.5e-22 77.2 0.0 4.4e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16500.1 - 1.2e-08 34.7 0.0 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KOS16500.1 - 0.027 14.3 0.0 2.2 8.1 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif DRMBL PF07522.9 KOS16501.1 - 3.1e-10 40.0 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KOS16501.1 - 1.6e-09 37.5 0.6 2.6e-09 36.9 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KOS16501.1 - 0.23 11.0 10.2 0.87 9.2 7.1 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Calreticulin PF00262.13 KOS16502.1 - 2.9e-157 523.0 8.8 4.2e-157 522.5 6.1 1.2 1 0 0 1 1 1 1 Calreticulin family Peptidase_S8 PF00082.17 KOS16502.1 - 2.4e-54 184.4 1.7 2.4e-54 184.4 1.2 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 KOS16502.1 - 7.6e-25 86.5 0.0 1.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain LuxS PF02664.10 KOS16502.1 - 0.21 11.1 0.1 0.78 9.2 0.0 1.9 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) Glyco_hydro_66 PF13199.1 KOS16502.1 - 0.26 9.6 0.1 0.45 8.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Apc1 PF12859.2 KOS16503.1 - 5.4e-09 36.2 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KOS16503.1 - 0.00022 21.2 17.5 0.0027 17.8 0.2 6.5 7 0 0 7 7 7 2 Proteasome/cyclosome repeat NST1 PF13945.1 KOS16505.1 - 9.7e-23 81.2 2.5 7.3e-21 75.1 0.1 4.8 4 1 1 5 5 5 2 Salt tolerance down-regulator MIP-T3 PF10243.4 KOS16505.1 - 3.2e-09 35.7 57.7 4.4e-09 35.3 34.9 2.3 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 Lipin_N PF04571.9 KOS16505.1 - 0.37 10.4 0.1 0.7 9.5 0.1 1.4 1 0 0 1 1 1 0 lipin, N-terminal conserved region Kelch_4 PF13418.1 KOS16506.1 - 1.6e-14 53.3 7.7 1.2e-06 28.1 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KOS16506.1 - 7e-14 51.4 2.8 9.8e-06 25.4 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KOS16506.1 - 2.3e-12 46.6 11.4 4.1e-05 23.6 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KOS16506.1 - 2.8e-08 33.5 5.6 0.014 15.5 0.1 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.10 KOS16506.1 - 0.00058 19.5 2.4 0.0031 17.2 0.0 3.4 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 KOS16506.1 - 0.058 12.9 3.2 0.81 9.2 0.0 3.7 3 0 0 3 3 3 0 Kelch motif RRM_6 PF14259.1 KOS16507.1 - 2.1e-12 46.8 0.0 4.6e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16507.1 - 9.8e-12 44.5 0.4 1.9e-08 34.0 0.1 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KOS16507.1 - 2.8e-07 30.0 0.0 8e-05 22.1 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KOS16507.1 - 8.7e-07 28.4 4.8 2e-06 27.2 3.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 KOS16507.1 - 1.1e-05 25.1 0.1 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PWI PF01480.12 KOS16507.1 - 3.2e-05 23.9 0.0 7.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain Phage_prot_Gp6 PF05133.9 KOS16507.1 - 0.032 12.7 3.6 0.32 9.5 0.6 2.1 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like RRM_3 PF08777.6 KOS16507.1 - 0.079 12.8 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 RNA binding motif DUF4140 PF13600.1 KOS16507.1 - 0.27 11.6 4.1 9.9 6.6 0.0 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) SET PF00856.23 KOS16508.1 - 8.2e-07 29.4 0.0 2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 SET domain DUF2407_C PF13373.1 KOS16509.1 - 2.4e-11 43.7 6.4 2.4e-11 43.7 4.4 3.6 3 1 0 3 3 3 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KOS16509.1 - 6.9e-09 35.7 0.0 2.4e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KOS16509.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Nucleo_P87 PF07267.6 KOS16509.1 - 0.027 13.1 2.9 0.035 12.8 2.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sigma70_ner PF04546.8 KOS16509.1 - 0.072 12.6 7.9 0.15 11.6 5.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 KOS16509.1 - 0.087 12.5 10.4 0.17 11.5 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ubiquitin PF00240.18 KOS16509.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Nucleoplasmin PF03066.10 KOS16509.1 - 0.18 11.3 6.5 0.29 10.6 4.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 KOS16509.1 - 0.47 8.2 3.8 0.64 7.8 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 KOS16509.1 - 0.61 10.4 14.1 0.4 11.0 7.8 2.1 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KOS16509.1 - 1.3 8.7 5.3 0.3 10.7 1.3 1.7 2 0 0 2 2 2 0 FAM176 family BTV_NS2 PF04514.7 KOS16509.1 - 1.7 7.4 8.2 3 6.6 5.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 KOS16509.1 - 2.9 6.6 6.7 4.3 6.0 4.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 KOS16509.1 - 4.1 6.5 8.0 5.9 6.0 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 KOS16509.1 - 6.4 4.6 9.3 9.3 4.1 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_2 PF12756.2 KOS16510.1 - 4.4e-38 129.4 11.7 3e-29 101.1 0.1 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KOS16510.1 - 5.7e-08 32.6 9.9 2.2e-06 27.6 3.4 3.1 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KOS16510.1 - 2.6e-06 27.4 4.9 2.6e-06 27.4 3.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KOS16510.1 - 0.00062 19.5 2.9 0.00062 19.5 2.0 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-DBF PF07535.7 KOS16510.1 - 0.011 15.3 0.9 0.011 15.3 0.6 2.7 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.21 KOS16510.1 - 0.029 14.7 3.9 0.029 14.7 2.7 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KOS16510.1 - 0.03 14.6 2.4 0.03 14.6 1.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Spatacsin_C PF14649.1 KOS16510.1 - 0.041 12.7 1.6 0.067 12.0 1.1 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus DUF629 PF04780.7 KOS16510.1 - 0.1 11.1 5.4 0.37 9.2 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Colicin_immun PF09204.5 KOS16510.1 - 0.22 11.5 4.5 0.55 10.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity AKAP95 PF04988.7 KOS16510.1 - 0.39 10.4 9.2 1.4 8.6 0.6 2.9 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) TPR_MLP1_2 PF07926.7 KOS16510.1 - 0.43 10.3 7.9 0.92 9.2 5.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SLX9 PF15341.1 KOS16510.1 - 0.62 10.5 8.9 0.04 14.3 2.3 1.9 2 0 0 2 2 1 0 Ribosome biogenesis protein SLX9 Vps39_2 PF10367.4 KOS16510.1 - 0.79 9.9 6.3 1.4 9.1 0.6 2.8 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 CRC_subunit PF08624.5 KOS16511.1 - 1.8e-48 164.0 0.4 3.6e-48 163.0 0.0 1.6 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit CAF1 PF04857.15 KOS16512.1 - 4.4e-63 213.0 0.0 6.1e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Pirin PF02678.11 KOS16513.1 - 8.8e-29 99.5 0.2 1.5e-27 95.5 0.1 2.6 3 0 0 3 3 3 1 Pirin Pirin_C PF05726.8 KOS16513.1 - 3.4e-24 84.9 0.0 1.1e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KOS16513.1 - 0.4 10.2 8.3 0.078 12.4 0.9 2.9 3 1 0 3 3 3 0 Cupin domain WD40 PF00400.27 KOS16514.1 - 1.8e-10 40.2 2.5 0.46 10.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1308 PF07000.6 KOS16515.1 - 6.9e-19 67.7 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Peptidase_S10 PF00450.17 KOS16516.1 - 1.1e-91 308.0 1.1 1.9e-91 307.3 0.7 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Josephin PF02099.12 KOS16517.1 - 3.9e-44 150.0 0.5 6.8e-44 149.2 0.4 1.4 1 0 0 1 1 1 1 Josephin UIM PF02809.15 KOS16517.1 - 0.00044 19.5 12.9 0.0029 17.0 0.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif Metallophos PF00149.23 KOS16518.1 - 1.3e-41 142.1 0.0 1.7e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GKAP PF03359.8 KOS16518.1 - 0.36 10.4 1.5 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein AMP-binding PF00501.23 KOS16519.1 - 2.6e-78 263.2 0.0 3.5e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KOS16519.1 - 5.3e-10 40.1 0.1 4.2e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Lgl_C PF08596.5 KOS16520.1 - 2.2e-19 69.2 0.0 3.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KOS16520.1 - 0.0064 16.3 0.0 1.1 9.3 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Imm43 PF15602.1 KOS16520.1 - 0.056 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 43 DUF3312 PF11768.3 KOS16520.1 - 0.094 10.9 0.0 3.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Nup160 PF11715.3 KOS16520.1 - 0.12 10.5 0.0 0.53 8.3 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Peptidase_S10 PF00450.17 KOS16521.1 - 5.5e-89 299.2 4.0 7.5e-89 298.7 2.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.20 KOS16522.1 - 5e-07 29.1 0.0 7.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KOS16522.1 - 0.002 17.2 0.0 0.0044 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 KOS16522.1 - 0.13 12.4 0.3 1.5 9.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat GFO_IDH_MocA PF01408.17 KOS16524.1 - 3.4e-16 59.8 0.0 5.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KOS16524.1 - 4.3e-09 36.1 0.0 8.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KOS16524.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Atg8 PF02991.11 KOS16525.1 - 7.6e-49 163.9 0.1 8.8e-49 163.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KOS16525.1 - 7e-07 29.3 0.0 9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_9 PF14604.1 KOS16525.1 - 0.061 12.9 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain DUF2407 PF10302.4 KOS16525.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain OPT PF03169.10 KOS16526.1 - 1.9e-144 482.4 56.5 2.3e-144 482.2 39.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein JAB PF01398.16 KOS16527.1 - 1.9e-19 69.4 0.1 3.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KOS16527.1 - 1.1e-10 41.5 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PQ-loop PF04193.9 KOS16528.1 - 1.5e-26 91.6 1.7 8.8e-14 50.8 0.6 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KOS16528.1 - 0.0017 18.2 4.9 0.029 14.2 0.7 2.5 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF3185 PF11381.3 KOS16528.1 - 0.012 15.3 2.3 0.02 14.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF998 PF06197.8 KOS16528.1 - 0.36 10.1 9.5 0.059 12.6 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF998) ER_lumen_recept PF00810.13 KOS16528.1 - 0.44 11.0 6.8 0.5 10.8 3.9 1.7 1 1 0 1 1 1 0 ER lumen protein retaining receptor CDC50 PF03381.10 KOS16529.1 - 5.1e-88 294.8 0.0 6.7e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family NDUFB10 PF10249.4 KOS16530.1 - 0.0048 17.0 0.6 0.0053 16.8 0.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF3492 PF11997.3 KOS16530.1 - 0.1 12.1 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Ribosomal_S16 PF00886.14 KOS16531.1 - 1.6e-28 98.1 0.3 2.3e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Prp19_bind PF06991.6 KOS16532.1 - 4.3e-53 180.3 11.2 4.3e-53 180.3 7.8 1.6 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain MBF1 PF08523.5 KOS16533.1 - 1.4e-14 53.8 0.6 2.5e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KOS16533.1 - 4.6e-14 51.9 0.1 8.7e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KOS16533.1 - 2.1e-07 30.8 0.1 2.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KOS16533.1 - 3e-05 24.1 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 KOS16533.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CPSase_L_D2 PF02786.12 KOS16534.1 - 6.7e-106 352.2 0.0 6.9e-82 273.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KOS16534.1 - 9.4e-43 144.8 0.3 2.7e-42 143.3 0.1 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KOS16534.1 - 5.8e-39 133.7 0.2 2.5e-19 69.7 0.1 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KOS16534.1 - 8.4e-35 119.2 0.0 1.3e-17 63.9 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KOS16534.1 - 5.8e-28 97.5 0.0 1.9e-12 46.5 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KOS16534.1 - 4.7e-19 68.3 0.0 4.1e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KOS16534.1 - 5.5e-13 48.7 0.0 4.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KOS16534.1 - 3.3e-07 30.3 0.0 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 KOS16534.1 - 8.4e-07 28.6 0.0 0.00088 18.7 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KOS16534.1 - 1.2e-05 24.6 0.2 0.053 12.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KOS16534.1 - 0.0015 18.1 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.16 KOS16534.1 - 0.0098 15.3 0.0 0.75 9.1 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family MGS PF02142.17 KOS16534.1 - 0.032 14.1 0.0 0.19 11.6 0.0 2.5 2 1 0 2 2 2 0 MGS-like domain DUF500 PF04366.7 KOS16535.1 - 2.1e-35 120.8 0.3 3.5e-35 120.1 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KOS16535.1 - 1.7e-13 49.7 0.2 3.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KOS16535.1 - 5.8e-08 32.1 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KOS16535.1 - 3.6e-07 29.6 0.1 7.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CTP_transf_2 PF01467.21 KOS16536.1 - 1.4e-29 103.1 0.0 2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase APC10 PF03256.11 KOS16537.1 - 2.4e-47 161.0 0.3 3.8e-47 160.4 0.0 1.4 2 0 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) BBP1_C PF15272.1 KOS16537.1 - 0.0053 16.3 0.9 0.0076 15.8 0.6 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal FrhB_FdhB_C PF04432.8 KOS16537.1 - 0.022 14.1 0.0 0.17 11.2 0.0 2.0 1 1 1 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Mito_carr PF00153.22 KOS16538.1 - 3.1e-46 155.0 0.1 1.9e-16 59.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 KOS16539.1 - 5.1e-38 130.2 0.0 9.3e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KOS16539.1 - 3e-28 97.4 0.0 2.9e-27 94.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NAD_binding_3 PF03447.11 KOS16539.1 - 0.017 15.4 0.3 0.19 12.1 0.0 2.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain ResIII PF04851.10 KOS16539.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KOS16539.1 - 0.04 14.0 1.1 0.26 11.4 0.1 2.8 3 1 0 3 3 3 0 AAA domain SNF2_N PF00176.18 KOS16539.1 - 0.048 12.4 0.0 0.098 11.4 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain PIF1 PF05970.9 KOS16539.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DsrH PF04077.7 KOS16539.1 - 0.068 12.8 0.3 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein Helicase_C_2 PF13307.1 KOS16539.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain NADH_dehy_S2_C PF06444.6 KOS16539.1 - 0.49 10.7 1.2 0.52 10.6 0.0 1.6 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus ERG2_Sigma1R PF04622.7 KOS16540.1 - 2.4e-90 301.5 0.1 2.9e-90 301.2 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein tRNA-synt_2b PF00587.20 KOS16541.1 - 5.5e-21 74.9 0.0 2.6e-20 72.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 KOS16541.1 - 3.7e-09 36.4 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Seryl_tRNA_N PF02403.17 KOS16541.1 - 0.014 15.3 2.4 0.024 14.6 1.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1279 PF06916.8 KOS16541.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) TPR_14 PF13428.1 KOS16541.1 - 4.3 8.2 11.2 6.7 7.6 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat GalP_UDP_transf PF01087.17 KOS16542.1 - 1.2e-60 204.7 0.1 2.1e-60 203.9 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KOS16542.1 - 1.4e-44 151.6 0.0 2.4e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain TPT PF03151.11 KOS16543.1 - 1.1e-22 80.2 12.7 1.1e-22 80.2 8.8 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KOS16543.1 - 0.0015 17.5 25.1 0.0034 16.3 17.4 1.5 1 1 0 1 1 1 1 UAA transporter family DUF1118 PF06549.7 KOS16543.1 - 4.7 7.3 8.9 1.1 9.3 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1118) Sec63 PF02889.11 KOS16544.1 - 5.4e-69 232.8 0.0 8.2e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KOS16544.1 - 7.1e-31 106.9 0.2 5.7e-28 97.5 0.1 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KOS16544.1 - 4.2e-09 36.5 0.0 7.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KOS16544.1 - 3.4e-06 26.8 0.0 3e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KOS16544.1 - 0.0051 16.9 0.3 0.049 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AA_kinase PF00696.23 KOS16545.1 - 4.5e-39 134.4 0.3 5.8e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KOS16545.1 - 9.7e-16 57.2 1.5 1.5e-14 53.4 0.1 2.5 2 0 0 2 2 2 1 PUA domain CBS PF00571.23 KOS16545.1 - 0.024 14.4 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 CBS domain PGK PF00162.14 KOS16545.1 - 0.083 11.4 0.2 0.36 9.3 0.1 1.7 1 1 0 2 2 2 0 Phosphoglycerate kinase UCH PF00443.24 KOS16546.1 - 6.6e-48 163.1 0.0 8e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS16546.1 - 1.5e-19 70.5 0.0 4.2e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KOS16546.1 - 3.2e-09 36.0 0.1 8.3e-09 34.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family UPF0564 PF10595.4 KOS16546.1 - 0.11 11.3 0.2 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Abhydrolase_5 PF12695.2 KOS16547.1 - 4.8e-23 81.5 0.0 9e-23 80.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KOS16547.1 - 3.7e-18 66.2 0.1 1.5e-16 60.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KOS16547.1 - 2.3e-07 30.4 0.1 0.00088 18.7 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 KOS16547.1 - 2.4e-07 30.2 0.0 8.8e-06 25.1 0.0 2.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KOS16547.1 - 2.6e-07 30.3 0.0 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KOS16547.1 - 1e-06 28.4 0.0 0.0007 19.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 KOS16547.1 - 1.1e-06 28.5 0.0 2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 KOS16547.1 - 2.2e-06 26.4 0.5 0.0016 17.0 0.0 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KOS16547.1 - 6.2e-06 25.9 0.3 2.5e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KOS16547.1 - 1.9e-05 24.0 0.1 0.18 10.9 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 KOS16547.1 - 0.00041 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 KOS16547.1 - 0.0076 15.7 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KOS16547.1 - 0.021 14.6 0.1 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 KOS16547.1 - 0.063 11.5 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II LIP PF03583.9 KOS16547.1 - 0.13 11.4 0.1 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase SelR PF01641.13 KOS16548.1 - 4.7e-53 178.1 0.3 5.3e-53 177.9 0.2 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 KOS16548.1 - 0.026 14.2 1.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 KOS16548.1 - 0.057 13.2 2.5 0.18 11.6 1.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Yippee-Mis18 PF03226.9 KOS16548.1 - 0.25 11.3 3.9 2.7 8.1 2.7 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.7 KOS16548.1 - 1.1 8.5 4.2 1.2 8.5 0.1 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 KOS16548.1 - 1.9 7.9 7.3 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Phage_int_SAM_1 PF02899.12 KOS16549.1 - 0.057 13.5 1.2 0.23 11.6 0.1 2.3 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2348 PF09807.4 KOS16551.1 - 9.9e-10 37.9 0.2 0.00063 18.9 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2348) HTH_31 PF13560.1 KOS16551.1 - 0.13 12.4 1.1 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Slx4 PF09494.5 KOS16552.1 - 1.8e-10 40.4 0.0 3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease SAP PF02037.22 KOS16552.1 - 0.0032 16.9 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain PTA_PTB PF01515.14 KOS16552.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF1829 PF08862.5 KOS16552.1 - 0.38 11.0 3.9 1 9.7 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF1829 DUF2421 PF10334.4 KOS16553.1 - 0.028 14.0 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF1115 PF06544.7 KOS16554.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) EnY2 PF10163.4 KOS16555.1 - 5.2e-14 51.9 0.0 6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF4127 PF13552.1 KOS16555.1 - 0.09 11.1 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) COX16 PF14138.1 KOS16556.1 - 1.6e-25 89.0 0.0 2.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.8 KOS16556.1 - 6.6e-25 86.8 1.0 1.4e-24 85.8 0.1 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DAHP_synth_1 PF00793.15 KOS16557.1 - 3.7e-93 311.1 0.0 4.3e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DnaJ PF00226.26 KOS16558.1 - 2.2e-25 88.1 0.9 3.5e-25 87.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KOS16558.1 - 5e-19 67.9 0.0 3.1e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KOS16558.1 - 1.3e-13 50.7 20.9 2.2e-13 50.0 14.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 KOS16558.1 - 0.0026 18.0 7.6 0.0058 16.9 5.3 1.6 1 0 0 1 1 1 1 Cytochrome c3 HypA PF01155.14 KOS16558.1 - 0.25 11.0 7.2 1.2 8.8 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lyase_1 PF00206.15 KOS16559.1 - 1.3e-95 320.2 0.0 1.8e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KOS16559.1 - 1.6e-29 101.7 0.1 3.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF3802 PF12290.3 KOS16559.1 - 0.11 12.8 0.1 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) XPA_C PF05181.7 KOS16560.1 - 5.9e-23 80.2 4.2 6.9e-22 76.7 2.9 2.2 1 1 0 1 1 1 1 XPA protein C-terminus SPT6_acidic PF14632.1 KOS16560.1 - 3.6 7.8 10.9 0.1 12.7 1.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SET PF00856.23 KOS16561.1 - 8.1e-22 78.2 0.3 8.1e-22 78.2 0.2 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KOS16561.1 - 4e-14 52.3 0.7 1.1e-13 50.9 0.5 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain BTG PF07742.7 KOS16561.1 - 0.074 12.5 0.1 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 BTG family HEAT PF02985.17 KOS16562.1 - 2.3e-19 67.6 7.7 0.00048 19.9 0.0 9.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 KOS16562.1 - 5.2e-14 52.2 15.3 5.7e-05 23.4 0.0 9.0 7 1 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.1 KOS16562.1 - 1.6e-12 47.5 15.2 3.8e-05 23.8 0.0 7.5 2 1 4 7 7 7 3 HEAT repeats IBN_N PF03810.14 KOS16562.1 - 5.6e-11 42.2 0.6 2e-09 37.2 0.0 3.0 3 0 0 3 3 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KOS16562.1 - 5.2e-05 21.7 0.4 0.0072 14.6 0.0 3.1 2 1 1 3 3 3 2 Adaptin N terminal region ParcG PF10274.4 KOS16562.1 - 0.0011 18.9 0.0 0.0044 16.9 0.0 2.0 2 0 0 2 2 2 1 Parkin co-regulated protein MMS19_N PF14500.1 KOS16562.1 - 0.0019 17.4 0.5 0.5 9.5 0.1 2.9 2 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.7 KOS16562.1 - 0.0038 16.9 1.4 8.7 5.9 0.0 4.9 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis Arm PF00514.18 KOS16562.1 - 0.0044 16.7 1.9 5.4 6.9 0.0 3.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 KOS16562.1 - 0.005 15.1 0.0 3.3 5.8 0.0 3.0 2 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 KOS16562.1 - 0.025 13.9 0.0 5.3 6.3 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal DUF383 PF04063.9 KOS16562.1 - 0.077 12.5 0.1 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Sec7_N PF12783.2 KOS16562.1 - 0.12 11.8 0.2 8 5.8 0.0 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SNF2_N PF00176.18 KOS16563.1 - 3.2e-81 272.4 0.1 5e-81 271.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KOS16563.1 - 1.1e-39 134.7 0.1 3.8e-39 133.0 0.1 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KOS16563.1 - 2.7e-29 101.8 4.2 2.7e-29 101.8 2.9 3.5 3 0 0 3 3 2 1 HAND Helicase_C PF00271.26 KOS16563.1 - 1.3e-14 53.7 0.0 1.9e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KOS16563.1 - 7.6e-11 41.3 0.0 1.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KOS16563.1 - 2.1e-07 30.9 0.0 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KOS16563.1 - 9.9e-07 28.3 0.0 2.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 KOS16563.1 - 0.00085 19.3 0.4 0.00085 19.3 0.3 3.7 5 0 0 5 5 4 1 DNA-binding domain Myb_DNA-binding PF00249.26 KOS16563.1 - 0.0079 16.2 0.0 0.048 13.7 0.0 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_14 PF13173.1 KOS16563.1 - 0.016 15.0 0.2 0.077 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Lactamase_B_5 PF14597.1 KOS16563.1 - 0.016 14.5 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DEAD_2 PF06733.10 KOS16563.1 - 0.033 13.6 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 ATP_sub_h PF10775.4 KOS16564.1 - 5.5e-22 77.2 3.2 5.5e-22 77.2 2.2 1.9 1 1 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KOS16564.1 - 0.11 12.4 0.4 0.18 11.7 0.3 1.8 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 UCH PF00443.24 KOS16565.1 - 2.4e-67 226.8 0.0 4.2e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KOS16565.1 - 6.3e-23 81.6 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KOS16565.1 - 1e-08 35.5 0.0 3.6e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain USP8_dimer PF08969.6 KOS16565.1 - 0.00033 20.5 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain zf-MIZ PF02891.15 KOS16565.1 - 0.016 14.7 2.9 0.037 13.5 0.6 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger WD40 PF00400.27 KOS16566.1 - 2e-34 116.2 2.3 6.3e-09 35.3 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.6 KOS16566.1 - 2.6e-27 94.3 0.9 6.9e-27 92.9 0.6 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 KOS16566.1 - 0.00015 21.6 0.0 0.00044 20.1 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 KOS16566.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF4347 PF14252.1 KOS16566.1 - 0.072 12.5 0.1 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Rtf2 PF04641.7 KOS16566.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1076 PF06416.7 KOS16566.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Pribosyltran PF00156.22 KOS16567.1 - 1.1e-07 31.5 0.1 2.8e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GTP_EFTU PF00009.22 KOS16568.1 - 1.6e-33 115.7 0.0 4.8e-33 114.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KOS16568.1 - 4.1e-17 62.0 0.0 1.2e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KOS16568.1 - 4.4e-15 55.5 4.6 6.4e-11 42.2 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 KOS16568.1 - 0.0038 16.7 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KOS16568.1 - 0.0055 17.1 0.0 0.023 15.1 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KOS16568.1 - 0.071 13.2 0.6 0.41 10.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KOS16568.1 - 0.33 10.9 0.0 0.33 10.9 0.0 3.7 4 0 0 4 4 4 0 AAA ATPase domain DUF962 PF06127.6 KOS16569.1 - 8.1e-24 83.3 0.0 1.9e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) P53_C PF11619.3 KOS16569.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain RRM_1 PF00076.17 KOS16570.1 - 7.4e-19 67.1 0.1 9.4e-19 66.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KOS16570.1 - 7.5e-15 54.6 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KOS16570.1 - 3.8e-08 33.0 0.0 5.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 KOS16571.1 - 4e-10 39.1 41.9 0.0012 18.3 0.0 11.1 9 4 5 14 14 14 5 TPR repeat TPR_16 PF13432.1 KOS16571.1 - 8.2e-08 32.7 9.7 4.7e-05 23.9 0.3 13.6 8 4 4 13 13 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 KOS16571.1 - 3.8e-06 26.9 30.8 0.00098 19.4 0.2 9.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KOS16571.1 - 1.4e-05 24.5 21.4 0.31 10.7 0.1 9.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KOS16571.1 - 1.5e-05 24.5 45.2 0.0062 16.3 0.4 12.7 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_14 PF13428.1 KOS16571.1 - 4.3e-05 23.7 1.4 4.3e-05 23.7 0.9 18.1 12 4 7 19 19 18 3 Tetratricopeptide repeat TPR_8 PF13181.1 KOS16571.1 - 0.00023 20.7 2.0 0.34 10.8 0.0 5.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KOS16571.1 - 0.0011 18.5 26.0 0.015 15.0 0.1 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat SHD1 PF03983.7 KOS16571.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 DUF2852 PF11014.3 KOS16571.1 - 0.19 11.7 3.2 0.59 10.0 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_17 PF13431.1 KOS16571.1 - 0.67 10.2 21.9 5.4 7.4 0.1 8.3 10 0 0 10 10 8 0 Tetratricopeptide repeat Ank_5 PF13857.1 KOS16572.1 - 0.015 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PseudoU_synth_1 PF01416.15 KOS16573.1 - 1.5e-23 83.1 0.0 8.7e-13 48.6 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase SET PF00856.23 KOS16573.1 - 3.1e-08 34.0 0.0 1.5e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 SET domain Mito_carr PF00153.22 KOS16574.1 - 2.4e-50 168.1 4.6 1.9e-16 59.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KOS16574.1 - 0.00095 19.0 0.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase SDA1 PF05285.7 KOS16575.1 - 8.5e-83 278.3 33.0 8.5e-83 278.3 22.9 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KOS16575.1 - 8.6e-20 70.7 0.1 2.8e-19 69.1 0.0 2.0 1 0 0 1 1 1 1 NUC130/3NT domain DUF2456 PF10445.4 KOS16576.1 - 2.5e-23 81.7 2.3 4.8e-23 80.8 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) SH3_1 PF00018.23 KOS16577.1 - 6.2e-13 47.9 0.0 8.9e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KOS16577.1 - 1.8e-08 33.8 0.0 2.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KOS16577.1 - 3.9e-08 32.6 0.0 5.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KOS16577.1 - 0.0025 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain ZZ PF00569.12 KOS16578.1 - 5.1e-11 41.9 3.7 1.1e-09 37.6 0.9 2.2 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_3 PF07649.7 KOS16578.1 - 0.13 12.3 8.2 0.77 9.8 3.6 2.2 2 0 0 2 2 2 0 C1-like domain C1_1 PF00130.17 KOS16578.1 - 0.5 10.1 4.3 8 6.2 1.3 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DIE2_ALG10 PF04922.7 KOS16579.1 - 3.2e-94 316.0 21.6 4.1e-94 315.7 15.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family dCMP_cyt_deam_1 PF00383.17 KOS16580.1 - 1.8e-25 88.5 1.8 2.9e-25 87.8 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KOS16580.1 - 6.1e-05 23.8 0.0 0.00012 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KOS16580.1 - 0.0013 18.6 0.0 0.0047 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 KOS16580.1 - 0.05 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase AAA_18 PF13238.1 KOS16580.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 KOS16580.1 - 0.16 11.3 0.1 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Vfa1 PF08432.5 KOS16581.1 - 1.3e-10 41.6 1.4 5.5e-07 29.7 0.2 2.0 1 1 1 2 2 2 2 AAA-ATPase Vps4-associated protein 1 5-FTHF_cyc-lig PF01812.15 KOS16583.1 - 2.5e-38 131.7 0.0 2.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Methyltransf_16 PF10294.4 KOS16584.1 - 1.6e-14 53.7 0.0 1.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KOS16584.1 - 0.008 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DPBB_1 PF03330.13 KOS16585.1 - 4.2e-07 29.8 0.1 9e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KOS16585.1 - 9.5e-06 25.2 0.4 1.5e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Barwin family YTH PF04146.10 KOS16585.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 YT521-B-like domain Indigoidine_A PF04227.7 KOS16586.1 - 1.7e-112 375.4 0.6 2.6e-112 374.8 0.4 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KOS16586.1 - 3e-21 75.8 0.1 6.6e-21 74.7 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase 4F5 PF04419.9 KOS16587.1 - 4.2e-11 43.3 11.4 4.2e-11 43.3 7.9 2.2 2 0 0 2 2 2 1 4F5 protein family IGF2_C PF08365.6 KOS16587.1 - 2.1 8.1 5.5 6.7 6.5 1.1 2.1 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide Cyt-b5 PF00173.23 KOS16588.1 - 1.1e-08 34.7 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DSBA PF01323.15 KOS16589.1 - 4.6e-26 91.5 0.0 5.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF605 PF04652.11 KOS16590.1 - 4.9e-71 240.1 2.9 7.3e-71 239.5 2.0 1.2 1 0 0 1 1 1 1 Vta1 like CoA_binding PF02629.14 KOS16590.1 - 2.3e-25 88.9 1.4 5.9e-24 84.3 0.1 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KOS16590.1 - 2.5e-21 75.8 0.0 4.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KOS16590.1 - 6e-06 25.9 0.0 4.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KOS16590.1 - 0.00056 20.0 0.0 0.0027 17.8 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 KOS16590.1 - 0.036 14.5 0.0 0.15 12.6 0.0 2.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L10 PF00466.15 KOS16591.1 - 1.7e-16 59.9 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Evr1_Alr PF04777.8 KOS16592.1 - 6.5e-29 99.6 0.5 1.1e-28 98.9 0.4 1.4 1 0 0 1 1 1 1 Erv1 / Alr family