# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Cu-oxidase_2 PF07731.9 EDP41365.1 - 6.3e-38 129.4 3.3 1.1e-37 128.6 2.3 1.4 1 0 0 1 1 1 1 Multicopper oxidase Na_Ca_ex PF01699.19 EDP41366.1 - 5.3e-18 64.9 3.6 8.3e-18 64.3 2.5 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Romo1 PF10247.4 EDP41366.1 - 0.088 13.0 1.1 0.15 12.2 0.7 1.5 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Defensin_2 PF01097.13 EDP41369.1 - 0.00011 21.8 10.5 0.00011 21.8 7.3 2.8 2 1 1 3 3 3 1 Arthropod defensin Defensin_2 PF01097.13 EDP41370.1 - 0.00035 20.2 12.5 0.00035 20.2 8.7 2.8 2 1 1 3 3 3 1 Arthropod defensin FMN_dh PF01070.13 EDP41371.1 - 2.5e-116 388.4 0.0 2.8e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EDP41371.1 - 1.8e-05 24.0 0.5 3.7e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDP41371.1 - 0.00022 20.2 0.2 0.00049 19.1 0.1 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EDP41371.1 - 0.0024 17.0 0.2 0.24 10.4 0.1 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EDP41371.1 - 0.0025 16.7 0.2 0.0041 16.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EDP41371.1 - 0.0058 15.9 0.2 0.11 11.7 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Ricin_B_lectin PF00652.17 EDP41372.1 - 0.012 15.6 0.3 0.13 12.3 0.2 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Asp PF00026.18 EDP41373.1 - 1.5e-31 109.8 0.0 1.8e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP41373.1 - 9.3e-05 22.8 0.0 0.056 13.9 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDP41373.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF2730 PF10805.3 EDP41375.1 - 0.001 18.7 0.4 0.0012 18.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) HHH_7 PF14635.1 EDP41375.1 - 0.049 13.7 0.1 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF465 PF04325.8 EDP41375.1 - 0.24 11.1 1.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF2730 PF10805.3 EDP41377.1 - 0.0044 16.7 0.2 0.0078 15.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Defensin_2 PF01097.13 EDP41378.1 - 0.00035 20.2 12.5 0.00035 20.2 8.7 2.8 2 1 1 3 3 3 1 Arthropod defensin Ricin_B_lectin PF00652.17 EDP41380.1 - 0.012 15.6 0.3 0.14 12.1 0.2 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Asp PF00026.18 EDP41381.1 - 9.8e-41 140.0 0.0 4.3e-40 137.8 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP41381.1 - 3.5e-07 30.6 0.1 0.021 15.2 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDP41381.1 - 0.00036 20.1 0.0 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Cu-oxidase_2 PF07731.9 EDP41383.1 - 3e-43 146.6 4.5 9.5e-38 128.8 0.5 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EDP41383.1 - 7.2e-35 120.2 0.6 1.5e-34 119.2 0.1 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP41383.1 - 5.8e-26 90.5 7.1 9e-23 80.2 0.2 4.7 3 3 0 3 3 3 2 Multicopper oxidase GspH PF12019.3 EDP41383.1 - 0.048 13.7 0.2 7.2 6.7 0.2 3.2 3 1 1 4 4 4 0 Type II transport protein GspH Aldo_ket_red PF00248.16 EDP41384.1 - 3.7e-70 235.9 0.1 4.2e-70 235.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EDP41385.1 - 3.2e-16 58.9 44.4 5.4e-16 58.2 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDP41385.1 - 2.9e-07 29.2 12.2 2.9e-07 29.2 8.4 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein B5 PF03484.10 EDP41386.1 - 6.1e-14 51.6 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase B5 domain MFS_1 PF07690.11 EDP41388.1 - 4.3e-12 45.4 8.6 6.4e-12 44.8 6.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_2 PF07731.9 EDP41389.1 - 7.1e-40 135.7 4.3 2e-38 131.0 1.9 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EDP41389.1 - 9.9e-31 106.7 0.9 5.5e-30 104.3 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP41390.1 - 8.4e-18 64.2 0.0 9.9e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Arr-ms PF12120.3 EDP41390.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Rifampin ADP-ribosyl transferase FMN_dh PF01070.13 EDP41391.1 - 4.9e-66 222.9 0.5 5.7e-66 222.7 0.4 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EDP41391.1 - 4.9e-06 25.9 0.5 6.7e-06 25.4 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDP41391.1 - 6.4e-05 22.0 0.9 0.00016 20.6 0.2 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EDP41391.1 - 0.00029 19.9 0.2 0.067 12.2 0.1 2.1 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EDP41391.1 - 0.00061 19.1 0.2 0.026 13.7 0.0 2.1 1 1 2 3 3 3 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EDP41391.1 - 0.00065 18.7 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IGPS PF00218.16 EDP41391.1 - 0.064 12.2 0.5 0.95 8.4 0.0 2.0 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 EDP41391.1 - 0.098 11.5 0.2 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PcrB PF01884.12 EDP41391.1 - 0.13 11.4 2.1 4.5 6.4 0.2 2.1 1 1 1 2 2 2 0 PcrB family Chitin_synth_1 PF01644.12 EDP41393.1 - 1.1e-63 213.9 0.0 1.4e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDP41393.1 - 1.6e-20 72.5 0.0 2.9e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDP41393.1 - 1.1e-05 24.0 0.0 3.6e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase DASH_Ask1 PF08655.5 EDP41394.1 - 2.5e-30 104.0 1.5 4.7e-30 103.2 1.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Syntaxin_2 PF14523.1 EDP41394.1 - 0.034 14.1 0.3 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Syntaxin-like protein DUF1635 PF07795.6 EDP41394.1 - 0.047 13.0 0.4 0.092 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) OTU PF02338.14 EDP41395.1 - 1.2e-20 74.3 0.3 1.1e-19 71.1 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDP41395.1 - 0.013 14.8 0.0 0.047 13.0 0.0 1.8 1 1 0 1 1 1 0 Peptidase C65 Otubain Actin PF00022.14 EDP41396.1 - 7.1e-116 386.8 0.0 8.3e-116 386.6 0.0 1.0 1 0 0 1 1 1 1 Actin Phosphoesterase PF04185.9 EDP41397.1 - 1.7e-76 257.8 2.4 1.7e-76 257.8 1.7 1.8 2 0 0 2 2 2 1 Phosphoesterase family MFS_1 PF07690.11 EDP41398.1 - 8.1e-24 83.9 20.8 2.5e-23 82.3 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 EDP41399.1 - 1.2e-22 80.0 40.9 2.4e-22 79.1 27.7 1.8 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3040 PF11239.3 EDP41399.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Sugar_tr PF00083.19 EDP41400.1 - 5.6e-60 203.1 7.8 6.5e-60 202.9 5.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4294 PF14127.1 EDP41400.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) SHP PF03579.8 EDP41400.1 - 0.16 11.3 0.5 0.47 9.8 0.4 1.8 1 0 0 1 1 1 0 Small hydrophobic protein FtsH_ext PF06480.10 EDP41400.1 - 0.18 11.9 1.5 0.84 9.8 0.8 2.3 2 0 0 2 2 2 0 FtsH Extracellular GARS_A PF01071.14 EDP41401.1 - 1.9e-72 242.9 0.0 2.8e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 EDP41401.1 - 3.4e-33 114.8 0.0 1.1e-32 113.1 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.10 EDP41401.1 - 9.5e-32 109.4 0.1 6.3e-31 106.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EDP41401.1 - 4.9e-28 97.1 1.3 5.7e-27 93.7 0.2 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EDP41401.1 - 1.4e-18 66.9 0.4 1e-17 64.1 0.2 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 EDP41401.1 - 1.1e-07 30.9 0.0 2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EDP41401.1 - 3.7e-07 30.0 0.0 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EDP41401.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EDP41401.1 - 0.0039 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDP41401.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain WD40 PF00400.27 EDP41402.1 - 1.3e-25 88.2 10.5 5.6e-10 38.7 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDP41402.1 - 1.1e-20 73.2 0.1 3.8e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EDP41402.1 - 8.4e-06 25.6 0.0 4e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ricin_B_lectin PF00652.17 EDP41403.1 - 0.03 14.3 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Asp PF00026.18 EDP41404.1 - 5.2e-16 58.7 0.3 3.8e-11 42.8 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP41404.1 - 0.00074 19.9 0.2 0.27 11.7 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease SLA_LP_auto_ag PF05889.8 EDP41404.1 - 0.003 16.0 0.0 0.0041 15.6 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Tau95 PF09734.4 EDP41406.1 - 0.06 12.6 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit S1FA PF04689.8 EDP41406.1 - 0.18 11.6 1.2 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA ATP-synt_A PF00119.15 EDP41406.1 - 0.49 9.8 9.8 8.1 5.8 0.0 2.1 2 0 0 2 2 2 0 ATP synthase A chain DUF4181 PF13789.1 EDP41406.1 - 0.61 10.0 7.3 0.63 9.9 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) FA_desaturase PF00487.19 EDP41406.1 - 4.8 6.5 20.3 0.031 13.7 6.0 2.1 1 1 1 2 2 2 0 Fatty acid desaturase Defensin_2 PF01097.13 EDP41407.1 - 0.0044 16.7 10.2 0.0044 16.7 7.1 3.1 2 1 1 3 3 3 1 Arthropod defensin DUF2749 PF10907.3 EDP41407.1 - 0.44 10.4 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) MFS_2 PF13347.1 EDP41409.1 - 2.6e-08 32.6 5.2 2.6e-08 32.6 3.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EDP41409.1 - 3.5e-07 29.2 29.6 1.5e-06 27.1 1.7 2.7 3 1 0 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDP41409.1 - 0.005 16.5 5.3 0.73 9.6 0.0 3.8 3 0 0 3 3 3 2 MFS_1 like family GTP_EFTU PF00009.22 EDP41410.1 - 3.8e-40 137.3 0.0 5.6e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDP41410.1 - 1.8e-26 92.0 0.0 3.5e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EDP41410.1 - 9.2e-21 73.5 0.0 2.8e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 EDP41410.1 - 4.6e-07 30.3 0.0 8.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EDP41410.1 - 8.1e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP41410.1 - 1.5e-06 28.0 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EDP41410.1 - 4.1e-06 26.5 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.18 EDP41410.1 - 0.0029 17.4 0.0 0.057 13.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Ras PF00071.17 EDP41410.1 - 0.037 13.4 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Ras family SRPRB PF09439.5 EDP41410.1 - 0.076 12.2 0.1 0.29 10.3 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 EDP41411.1 - 7.4e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDP41411.1 - 4.2e-06 25.9 0.0 7.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDP41411.1 - 1.6e-05 25.0 0.0 0.00035 20.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP41411.1 - 3.8e-05 24.4 0.0 8.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDP41411.1 - 4e-05 23.5 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EDP41411.1 - 5.7e-05 21.9 0.0 0.0034 16.1 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EDP41411.1 - 8.5e-05 22.2 0.6 0.00056 19.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EDP41411.1 - 0.00022 21.1 0.0 0.0006 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDP41411.1 - 0.00024 21.1 1.8 0.052 13.5 0.1 3.9 4 1 1 5 5 5 1 AAA ATPase domain AAA_14 PF13173.1 EDP41411.1 - 0.00065 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP41411.1 - 0.00068 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EDP41411.1 - 0.0036 17.2 0.0 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDP41411.1 - 0.0037 16.6 0.3 1.3 8.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EDP41411.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EDP41411.1 - 0.015 15.0 0.1 0.11 12.1 0.0 2.0 1 1 1 2 2 2 0 NTPase Zeta_toxin PF06414.7 EDP41411.1 - 0.033 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EDP41411.1 - 0.035 13.7 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 NACHT domain KaiC PF06745.8 EDP41411.1 - 0.21 10.7 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EDP41411.1 - 0.23 11.7 0.0 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 EDP41412.1 - 4.4e-22 79.2 0.3 5.9e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDP41412.1 - 9.6e-06 25.2 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Brr6_like_C_C PF10104.4 EDP41412.1 - 0.0084 15.6 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.14 EDP41413.1 - 6.5e-56 189.3 0.0 9.2e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDP41413.1 - 0.00024 19.9 0.0 0.00035 19.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_L10 PF00466.15 EDP41414.1 - 6.7e-25 86.9 0.7 1.4e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EDP41414.1 - 2.1e-22 79.3 11.4 4.5e-22 78.2 6.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF4266 PF14086.1 EDP41415.1 - 0.37 11.3 0.1 0.37 11.3 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4266) ECH PF00378.15 EDP41416.1 - 4.1e-23 81.7 0.0 5.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Arc PF03869.9 EDP41416.1 - 0.0026 17.3 0.0 0.067 12.8 0.0 2.9 3 0 0 3 3 3 1 Arc-like DNA binding domain Peptidase_S49 PF01343.13 EDP41416.1 - 0.021 14.6 0.2 0.69 9.6 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 ECH PF00378.15 EDP41417.1 - 3.3e-19 69.0 0.0 4.5e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4269 PF14091.1 EDP41417.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Peptidase_S49 PF01343.13 EDP41417.1 - 0.11 12.2 0.0 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 WD40 PF00400.27 EDP41418.1 - 1e-07 31.5 6.8 0.14 12.0 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat SAS4 PF15460.1 EDP41419.1 - 7.2e-06 25.8 2.4 1.5e-05 24.7 1.7 1.6 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EDP41419.1 - 0.00076 19.9 0.9 0.00076 19.9 0.6 2.3 2 0 0 2 2 2 1 PEHE domain GLTSCR1 PF15249.1 EDP41419.1 - 0.72 9.9 6.7 4.2 7.5 0.0 2.9 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region CHORD PF04968.7 EDP41420.1 - 6.7e-45 151.1 13.4 7.5e-23 80.5 0.8 2.2 2 0 0 2 2 2 2 CHORD FAP PF07174.6 EDP41420.1 - 0.00085 18.7 7.9 0.0014 18.0 5.5 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) CS PF04969.11 EDP41420.1 - 0.0036 17.8 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 CS domain BTK PF00779.14 EDP41420.1 - 0.052 13.1 7.5 0.22 11.1 1.6 3.1 3 1 0 3 3 3 0 BTK motif DUF1375 PF07119.7 EDP41420.1 - 0.11 12.3 0.1 14 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) zf-C4H2 PF10146.4 EDP41422.1 - 0.056 13.4 0.8 0.42 10.5 0.5 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein ADH_zinc_N PF00107.21 EDP41423.1 - 2.8e-10 39.8 0.0 4.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP41423.1 - 2.6e-05 23.9 0.1 0.0001 21.9 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP41424.1 - 2.2e-05 23.9 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP41424.1 - 4e-05 23.3 0.3 0.0006 19.5 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP41425.1 - 3.8e-11 42.6 0.0 6.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP41425.1 - 8.8e-05 22.2 0.1 0.00033 20.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2730 PF10805.3 EDP41426.1 - 0.0045 16.7 0.3 0.0052 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) HHH_7 PF14635.1 EDP41426.1 - 0.059 13.4 0.1 0.068 13.2 0.0 1.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lge1 PF11488.3 EDP41426.1 - 0.14 12.3 0.6 0.2 11.8 0.4 1.5 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF465 PF04325.8 EDP41426.1 - 0.24 11.1 1.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Transp_cyt_pur PF02133.10 EDP41427.1 - 4.5e-30 104.5 32.8 7.1e-30 103.9 22.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_43 PF04616.9 EDP41428.1 - 4.6e-35 121.0 0.0 5.5e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_zinc_N PF00107.21 EDP41429.1 - 1.6e-24 85.8 0.0 3.6e-24 84.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP41429.1 - 2.9e-12 46.3 0.1 1.9e-11 43.6 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDP41429.1 - 7e-08 33.4 0.0 4.8e-07 30.7 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EDP41429.1 - 0.041 13.4 0.2 0.082 12.4 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EDP41429.1 - 0.13 12.2 1.3 0.66 9.9 0.2 2.1 2 0 0 2 2 2 0 NADH(P)-binding AA_kinase PF00696.23 EDP41430.1 - 3.2e-31 108.7 0.0 5.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EDP41430.1 - 1.8e-08 33.6 0.5 0.00039 19.8 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EDP41430.1 - 2.1e-08 33.5 1.5 0.00016 21.0 0.1 2.6 2 0 0 2 2 2 2 ACT domain Cse1 PF08506.5 EDP41431.1 - 8.1e-132 439.2 0.2 1.5e-131 438.3 0.2 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EDP41431.1 - 5.4e-116 387.4 0.1 1.2e-115 386.2 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EDP41431.1 - 2.3e-16 59.4 2.2 4e-14 52.2 0.1 3.4 3 0 0 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EDP41431.1 - 0.00024 21.0 0.4 0.00024 21.0 0.3 4.6 4 3 1 5 5 5 1 Exportin 1-like protein Cullin_binding PF03556.10 EDP41431.1 - 0.072 13.2 0.0 0.29 11.2 0.0 2.1 1 0 0 1 1 1 0 Cullin binding HEAT PF02985.17 EDP41431.1 - 0.71 10.1 9.4 3.5 7.9 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat RNB PF00773.14 EDP41432.1 - 4.2e-53 180.7 0.0 6.7e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EDP41432.1 - 0.025 14.0 0.0 0.058 12.8 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain NIF PF03031.13 EDP41433.1 - 1.4e-08 34.6 0.2 0.00072 19.2 0.0 2.1 1 1 0 2 2 2 2 NLI interacting factor-like phosphatase ACOX PF01756.14 EDP41434.1 - 2.8e-41 140.9 0.0 4.3e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EDP41434.1 - 5.1e-16 57.9 0.3 1.2e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EDP41434.1 - 2.9e-11 43.7 0.0 6.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EDP41434.1 - 1.5e-09 38.0 0.1 4.2e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mito_carr PF00153.22 EDP41435.1 - 4.7e-48 160.8 4.3 1.4e-21 75.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EDP41435.1 - 6.5e-05 22.9 0.2 0.00025 21.0 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDP41435.1 - 0.00019 21.0 0.0 0.0037 17.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EDP41435.1 - 0.00059 18.9 0.1 0.0086 15.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDP41435.1 - 0.019 14.5 0.1 0.089 12.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Tubulin PF00091.20 EDP41436.1 - 2.7e-69 233.2 0.0 3.7e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDP41436.1 - 2.2e-47 160.2 0.0 3.4e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDP41436.1 - 0.00049 19.6 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EDP41436.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain SRF-TF PF00319.13 EDP41437.1 - 1.9e-21 75.0 0.0 3e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-U1 PF06220.7 EDP41438.1 - 1.3e-07 31.0 0.9 2.3e-07 30.2 0.6 1.4 1 0 0 1 1 1 1 U1 zinc finger CPSF_A PF03178.10 EDP41439.1 - 1.1e-62 212.0 0.0 1.8e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Ribosomal_S26e PF01283.14 EDP41440.1 - 9.1e-19 67.7 0.3 1e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Glyco_hydro_16 PF00722.16 EDP41443.1 - 3.2e-21 75.4 0.2 6.2e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 cIII PF08134.6 EDP41443.1 - 0.02 14.4 0.3 0.051 13.1 0.2 1.6 1 0 0 1 1 1 0 cIII protein family bZIP_1 PF00170.16 EDP41444.1 - 0.025 14.5 0.6 0.025 14.5 0.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 EDP41444.1 - 0.15 11.8 1.5 0.36 10.5 1.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.12 EDP41444.1 - 0.29 11.4 11.7 0.54 10.5 7.7 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor YABBY PF04690.8 EDP41444.1 - 0.32 11.2 2.9 1.3 9.2 2.0 2.1 1 0 0 1 1 1 0 YABBY protein DDHD PF02862.12 EDP41445.1 - 1.9e-17 63.8 0.0 3.2e-12 46.7 0.0 3.4 2 1 1 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 EDP41445.1 - 0.032 14.1 0.7 0.11 12.3 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family WWE PF02825.15 EDP41445.1 - 0.085 12.2 0.5 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 WWE domain Abhydrolase_5 PF12695.2 EDP41445.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family N-SET PF11764.3 EDP41446.1 - 4.7e-12 46.1 3.0 4.7e-12 46.1 2.1 2.8 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EDP41446.1 - 1.3e-10 41.8 0.1 4.1e-09 36.9 0.0 2.7 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.3 EDP41446.1 - 0.029 13.6 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Carboxyl_trans PF01039.17 EDP41447.1 - 2.5e-46 158.0 0.0 3.1e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DEAD PF00270.24 EDP41448.1 - 4.7e-39 133.5 0.0 7.4e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP41448.1 - 4.4e-25 87.3 0.0 7.9e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDP41448.1 - 8.1e-06 24.8 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDP41448.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Spore_coat_CotO PF14153.1 EDP41448.1 - 0.82 9.0 7.0 0.71 9.2 3.6 1.7 2 0 0 2 2 2 0 Spore coat protein CotO BTV_NS2 PF04514.7 EDP41448.1 - 2.4 6.9 8.6 3.7 6.3 6.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MIP-T3 PF10243.4 EDP41448.1 - 3.6 5.9 17.2 4.6 5.5 11.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_L18e PF00828.14 EDP41449.1 - 3.7e-22 79.0 0.0 6.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 SNARE PF05739.14 EDP41450.1 - 2.8e-13 49.3 7.1 2.8e-13 49.3 4.9 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDP41450.1 - 4.2e-07 30.0 0.3 4.2e-07 30.0 0.2 3.5 3 0 0 3 3 3 1 Syntaxin DUF4094 PF13334.1 EDP41450.1 - 0.1 13.0 0.2 0.1 13.0 0.1 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) PBP1_TM PF14812.1 EDP41450.1 - 0.16 12.3 0.1 0.16 12.3 0.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF0941-like PF14591.1 EDP41450.1 - 2.1 8.3 6.7 15 5.6 0.7 3.6 2 2 2 4 4 4 0 AF0941-like Alg14 PF08660.6 EDP41451.1 - 3.4e-24 85.7 0.0 4.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PDH PF02153.12 EDP41452.1 - 4.6e-11 42.0 0.0 8.4e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EDP41452.1 - 0.00024 21.4 0.0 0.00071 19.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EDP41452.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EDP41452.1 - 0.024 13.7 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDP41452.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAHP_synth_1 PF00793.15 EDP41453.1 - 5.2e-88 294.2 0.0 6.3e-88 293.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 EDP41453.1 - 0.048 13.3 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 SRX TPP_enzyme_N PF02776.13 EDP41454.1 - 7.2e-22 77.6 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDP41454.1 - 3.9e-21 75.2 0.0 2.1e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDP41454.1 - 6e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EDP41454.1 - 0.0015 17.5 0.1 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Epimerase PF01370.16 EDP41455.1 - 1.2e-17 64.1 0.2 3.3e-17 62.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDP41455.1 - 1.5e-17 63.2 0.0 2.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDP41455.1 - 8.5e-16 58.4 0.0 1.9e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDP41455.1 - 8.7e-16 57.5 0.2 2.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EDP41455.1 - 3.9e-12 45.9 0.0 2.2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDP41455.1 - 9.8e-10 37.7 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDP41455.1 - 5.2e-06 26.4 0.1 2.1e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP41455.1 - 0.00075 19.2 1.1 0.013 15.1 0.2 2.9 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 EDP41455.1 - 0.028 13.3 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EDP41455.1 - 0.053 13.3 0.0 11 5.8 0.0 2.4 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EDP41456.1 - 4.1e-12 45.7 0.0 5.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDP41456.1 - 2.5e-06 28.3 0.0 4e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EDP41457.1 - 1.2e-63 215.3 0.0 1.5e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDP41457.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DUF787 PF05619.6 EDP41457.1 - 0.15 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) p450 PF00067.17 EDP41458.1 - 9.9e-31 106.7 0.3 1.4e-29 102.9 0.2 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pr_beta_C PF12465.3 EDP41458.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal MFS_1 PF07690.11 EDP41459.1 - 5.9e-42 143.6 60.8 4.8e-39 134.0 41.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP41459.1 - 2.2e-07 29.8 38.4 0.002 16.7 11.9 3.4 1 1 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.11 EDP41459.1 - 0.0032 16.2 14.3 0.079 11.6 9.9 3.0 1 1 0 1 1 1 1 BT1 family DUF3464 PF11947.3 EDP41459.1 - 0.15 11.5 4.3 0.38 10.2 2.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) TPP_enzyme_N PF02776.13 EDP41460.1 - 7.2e-22 77.6 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDP41460.1 - 3.9e-21 75.2 0.0 2.1e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDP41460.1 - 6e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EDP41460.1 - 0.0015 17.5 0.1 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Epimerase PF01370.16 EDP41461.1 - 1.2e-17 64.1 0.2 3.3e-17 62.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDP41461.1 - 1.5e-17 63.2 0.0 2.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDP41461.1 - 8.5e-16 58.4 0.0 1.9e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDP41461.1 - 8.7e-16 57.5 0.2 2.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EDP41461.1 - 3.9e-12 45.9 0.0 2.2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDP41461.1 - 9.8e-10 37.7 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDP41461.1 - 5.2e-06 26.4 0.1 2.1e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP41461.1 - 0.00075 19.2 1.1 0.013 15.1 0.2 2.9 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 EDP41461.1 - 0.028 13.3 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EDP41461.1 - 0.053 13.3 0.0 11 5.8 0.0 2.4 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EDP41462.1 - 4.1e-12 45.7 0.0 5.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDP41462.1 - 2.5e-06 28.3 0.0 4e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EDP41463.1 - 1.2e-63 215.3 0.0 1.5e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDP41463.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DUF787 PF05619.6 EDP41463.1 - 0.15 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) p450 PF00067.17 EDP41464.1 - 9.9e-31 106.7 0.3 1.4e-29 102.9 0.2 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pr_beta_C PF12465.3 EDP41464.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal MFS_1 PF07690.11 EDP41465.1 - 5.9e-42 143.6 60.8 4.8e-39 134.0 41.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP41465.1 - 2.2e-07 29.8 38.4 0.002 16.7 11.9 3.4 1 1 0 2 2 2 2 Sugar (and other) transporter BT1 PF03092.11 EDP41465.1 - 0.0032 16.2 14.3 0.079 11.6 9.9 3.0 1 1 0 1 1 1 1 BT1 family DUF3464 PF11947.3 EDP41465.1 - 0.15 11.5 4.3 0.38 10.2 2.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) TPP_enzyme_N PF02776.13 EDP41466.1 - 7.2e-22 77.6 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDP41466.1 - 3.9e-21 75.2 0.0 2.1e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDP41466.1 - 6e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EDP41466.1 - 0.0015 17.5 0.1 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Epimerase PF01370.16 EDP41467.1 - 1.2e-17 64.1 0.2 3.3e-17 62.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDP41467.1 - 1.5e-17 63.2 0.0 2.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDP41467.1 - 8.5e-16 58.4 0.0 1.9e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDP41467.1 - 8.7e-16 57.5 0.2 2.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EDP41467.1 - 3.9e-12 45.9 0.0 2.2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDP41467.1 - 9.8e-10 37.7 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDP41467.1 - 5.2e-06 26.4 0.1 2.1e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP41467.1 - 0.00075 19.2 1.1 0.013 15.1 0.2 2.9 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 EDP41467.1 - 0.028 13.3 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EDP41467.1 - 0.053 13.3 0.0 11 5.8 0.0 2.4 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EDP41468.1 - 2.5e-07 30.3 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDP41468.1 - 4.3e-06 27.6 0.0 6.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EDP41469.1 - 1.2e-63 215.3 0.0 1.5e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDP41469.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DUF787 PF05619.6 EDP41469.1 - 0.15 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) PDH PF02153.12 EDP41470.1 - 2.5e-11 42.9 0.0 4.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EDP41470.1 - 2.6e-05 24.5 0.0 7.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EDP41470.1 - 6.1e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EDP41470.1 - 0.00022 20.4 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDP41470.1 - 0.0022 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EDP41470.1 - 0.0029 17.0 0.0 0.0081 15.6 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 EDP41470.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 EDP41470.1 - 0.039 13.9 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 EDP41470.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EDP41470.1 - 0.14 11.8 0.0 0.63 9.6 0.0 2.0 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tim17 PF02466.14 EDP41473.1 - 7.6e-20 71.2 0.4 1.1e-19 70.7 0.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L27 PF01016.14 EDP41474.1 - 4.1e-31 106.6 0.1 7.5e-31 105.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF1014 PF06244.7 EDP41476.1 - 8e-23 80.9 7.3 9e-23 80.7 3.5 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) DUF2852 PF11014.3 EDP41476.1 - 0.0029 17.5 2.7 0.0029 17.5 1.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2852) DAO PF01266.19 EDP41477.1 - 2.1e-17 63.0 0.0 1.1e-07 31.1 0.1 2.0 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDP41477.1 - 6e-05 22.9 0.2 0.00015 21.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDP41477.1 - 8.3e-05 22.5 0.2 0.002 18.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDP41477.1 - 0.00093 19.5 0.3 0.002 18.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EDP41477.1 - 0.0036 17.5 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EDP41477.1 - 0.0039 16.0 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDP41477.1 - 0.004 16.2 0.0 0.0084 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EDP41477.1 - 0.0096 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EDP41477.1 - 0.016 15.2 0.0 0.064 13.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDP41477.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EDP41477.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EDP41477.1 - 0.11 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.1 EDP41477.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pyr_redox_3 PF13738.1 EDP41477.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2_jaz PF12171.3 EDP41478.1 - 3.1e-09 36.7 0.3 2.9e-08 33.6 0.8 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDP41478.1 - 0.00013 22.0 0.5 0.00023 21.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDP41478.1 - 0.0021 18.1 0.8 0.0021 18.1 0.5 1.7 1 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EDP41478.1 - 0.0054 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.1 EDP41478.1 - 0.069 13.5 1.4 0.21 11.9 0.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger AAL_decarboxy PF03306.8 EDP41478.1 - 0.09 11.8 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase zf-C2H2 PF00096.21 EDP41478.1 - 0.14 12.5 0.9 0.41 11.0 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_L35Ae PF01247.13 EDP41479.1 - 7.7e-41 137.7 1.0 8.8e-41 137.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EDP41479.1 - 0.0013 18.6 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DNA_pol_B PF00136.16 EDP41480.1 - 2e-111 373.0 0.5 2.9e-111 372.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EDP41480.1 - 3e-44 150.6 0.0 5.9e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EDP41480.1 - 2.2e-19 69.4 0.0 5.4e-19 68.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EDP41480.1 - 4.1e-07 29.7 5.3 9.1e-07 28.6 3.7 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal RED_N PF07808.8 EDP41481.1 - 0.00022 20.5 2.6 0.00051 19.3 1.8 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region Colicin_Pyocin PF01320.13 EDP41481.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Phos_pyr_kin PF08543.7 EDP41482.1 - 1.6e-09 37.3 0.0 3.9e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EDP41482.1 - 6.2e-09 35.4 0.0 7.7e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase A_deaminase PF00962.17 EDP41485.1 - 4.3e-106 354.5 0.1 6.1e-106 354.0 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PGK PF00162.14 EDP41486.1 - 7.4e-150 498.7 1.8 8.5e-150 498.5 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Aldo_ket_red PF00248.16 EDP41487.1 - 9.3e-35 119.8 0.0 1.7e-34 118.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Flavoprotein PF02441.14 EDP41488.1 - 8.3e-38 128.9 0.2 1.1e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein W2 PF02020.13 EDP41489.1 - 1.4e-12 47.3 0.7 1.4e-12 47.3 0.5 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EDP41489.1 - 4.8e-12 44.7 9.1 1.1e-05 24.6 1.2 4.3 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDP41489.1 - 4.8e-06 26.0 4.4 0.018 14.6 0.0 3.9 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EDP41489.1 - 5e-06 25.3 0.1 7.8e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.2 EDP41489.1 - 0.00042 20.4 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF3530 PF12048.3 EDP41489.1 - 0.14 11.1 0.2 5.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Voldacs PF03517.8 EDP41489.1 - 1.3 8.9 15.0 0.71 9.7 1.2 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Ran_BP1 PF00638.13 EDP41490.1 - 1.2e-09 38.2 0.4 2.3e-09 37.3 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain Kei1 PF08552.6 EDP41491.1 - 6.1e-44 149.9 2.0 9.3e-44 149.3 1.4 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 HycI PF01750.13 EDP41491.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease dsDNA_bind PF01984.15 EDP41492.1 - 5.7e-25 87.3 5.4 6.7e-25 87.1 3.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain GGDEF PF00990.16 EDP41492.1 - 0.036 13.6 0.2 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 GGDEF domain DUF2052 PF09747.4 EDP41492.1 - 0.17 11.7 2.1 2.1 8.2 0.1 2.0 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) tRNA_int_endo PF01974.12 EDP41494.1 - 1.3e-17 63.4 0.1 2e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EDP41494.1 - 0.0001 21.7 0.0 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain mRNA_cap_enzyme PF01331.14 EDP41495.1 - 1e-45 155.8 0.0 1.4e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EDP41495.1 - 1.3e-15 57.6 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EDP41495.1 - 5.5e-05 22.6 0.0 0.0016 17.8 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF581 PF04570.9 EDP41496.1 - 0.27 10.5 2.4 0.77 9.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF581) 2-Hacid_dh_C PF02826.14 EDP41497.1 - 9e-48 161.7 0.0 2.1e-47 160.5 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDP41497.1 - 1.1e-17 63.6 0.0 1.6e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDP41497.1 - 1.9e-06 27.7 0.2 1.1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EDP41497.1 - 0.0024 17.2 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pertus-S5-tox PF09276.5 EDP41498.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin S5 subunit DJ-1_PfpI PF01965.19 EDP41499.1 - 1e-18 67.2 0.0 2.6e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EDP41499.1 - 1.3e-05 24.6 0.0 3.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Aldo_ket_red PF00248.16 EDP41500.1 - 2.1e-32 112.1 0.0 2.6e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cu-oxidase_2 PF07731.9 EDP41501.1 - 4.5e-40 136.3 8.3 1.2e-36 125.3 2.6 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EDP41501.1 - 2.1e-34 118.7 0.3 6.5e-34 117.1 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP41501.1 - 4e-25 87.8 7.3 1.3e-21 76.4 0.1 5.1 4 2 1 6 6 6 2 Multicopper oxidase DUF1080 PF06439.6 EDP41501.1 - 0.019 14.8 0.1 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) GspH PF12019.3 EDP41501.1 - 0.077 13.1 0.2 7.3 6.7 0.1 2.8 2 1 1 3 3 3 0 Type II transport protein GspH DUF1214 PF06742.6 EDP41501.1 - 0.1 13.1 0.0 0.81 10.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1214) Ricin_B_lectin PF00652.17 EDP41502.1 - 0.077 13.0 0.8 8 6.5 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Catalase PF00199.14 EDP41503.1 - 5.9e-164 545.3 0.2 7.4e-164 544.9 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDP41503.1 - 2e-20 72.3 0.2 3.8e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EDP41503.1 - 0.00054 19.4 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family LIP PF03583.9 EDP41504.1 - 2.3e-60 204.2 0.0 2.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EDP41504.1 - 2.3e-05 24.1 0.0 5.4e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP41504.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDP41504.1 - 0.0025 17.0 0.8 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDP41504.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cu-oxidase PF00394.17 EDP41505.1 - 2.9e-23 82.5 0.2 4.5e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP41505.1 - 6.3e-23 80.7 3.9 2.1e-22 79.0 0.1 3.0 2 2 1 3 3 3 1 Multicopper oxidase GspH PF12019.3 EDP41505.1 - 0.0082 16.2 0.0 0.67 10.1 0.1 2.2 1 1 1 2 2 2 1 Type II transport protein GspH Cu-oxidase_2 PF07731.9 EDP41506.1 - 9.1e-40 135.3 1.7 1.3e-39 134.8 1.2 1.2 1 0 0 1 1 1 1 Multicopper oxidase Gp_dh_N PF00044.19 EDP41506.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Defensin_2 PF01097.13 EDP41508.1 - 0.00035 20.2 12.5 0.00035 20.2 8.7 2.8 2 1 1 3 3 3 1 Arthropod defensin DUF2730 PF10805.3 EDP41509.1 - 0.0018 17.9 0.3 0.0036 17.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF603 PF04645.7 EDP41509.1 - 0.014 15.3 1.3 0.019 14.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Lge1 PF11488.3 EDP41509.1 - 0.092 12.9 0.8 0.19 11.9 0.5 1.7 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Uds1 PF15456.1 EDP41509.1 - 0.67 9.9 4.2 1.1 9.2 0.7 2.3 2 1 0 2 2 2 0 Up-regulated During Septation Catalase PF00199.14 EDP41510.1 - 1.1e-165 550.9 0.2 1.4e-165 550.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDP41510.1 - 3.9e-21 74.6 0.2 7.2e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EDP41510.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Acetyltransf_2 PF00797.12 EDP41511.1 - 5.8e-60 202.8 0.0 6.7e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_C71 PF12386.3 EDP41511.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei Metallophos PF00149.23 EDP41513.1 - 0.011 15.1 0.6 0.021 14.2 0.4 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF676 PF05057.9 EDP41514.1 - 2.2e-06 27.1 0.0 4.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EDP41514.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDP41514.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Stimulus_sens_1 PF13756.1 EDP41514.1 - 0.0062 16.9 0.8 1.2 9.5 0.4 2.9 2 0 0 2 2 2 1 Stimulus-sensing domain Thioesterase PF00975.15 EDP41514.1 - 0.043 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.6 EDP41514.1 - 0.064 12.3 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Na_Ca_ex PF01699.19 EDP41515.1 - 1.6e-37 128.1 29.6 8.6e-22 77.2 6.3 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2036 PF09724.4 EDP41516.1 - 5.4e-39 134.2 0.0 6.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Sec8_exocyst PF04048.9 EDP41516.1 - 0.076 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ecl1 PF12855.2 EDP41517.1 - 7.2e-06 25.1 1.0 1.7e-05 23.9 0.7 1.6 1 1 0 1 1 1 1 Life-span regulatory factor Sld5 PF05916.6 EDP41518.1 - 0.028 14.7 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 GINS complex protein TnpB_IS66 PF05717.8 EDP41518.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 IS66 Orf2 like protein CAP_GLY PF01302.20 EDP41519.1 - 2.5e-24 84.7 1.5 4.5e-24 83.9 1.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EDP41519.1 - 1.6e-17 63.5 0.0 2.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Med9 PF07544.8 EDP41520.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Seryl_tRNA_N PF02403.17 EDP41521.1 - 0.0072 16.3 6.2 0.0072 16.3 4.3 12.8 4 2 9 13 13 13 6 Seryl-tRNA synthetase N-terminal domain COPIIcoated_ERV PF07970.7 EDP41522.1 - 1.3e-63 214.5 0.0 1.7e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDP41522.1 - 5.2e-31 106.4 0.0 1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Complex1_49kDa PF00346.14 EDP41523.1 - 6.7e-123 409.0 0.0 9.1e-123 408.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Bromodomain PF00439.20 EDP41524.1 - 2.9e-21 75.1 0.1 6.3e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Epsilon_antitox PF08998.6 EDP41524.1 - 0.042 13.8 0.2 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial epsilon antitoxin PRMT5 PF05185.11 EDP41525.1 - 1.9e-06 27.0 0.0 4.4e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EDP41525.1 - 5.4e-06 26.9 0.2 1.9e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDP41525.1 - 0.00023 20.3 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDP41525.1 - 0.00096 19.1 0.1 0.12 12.4 0.2 2.6 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP41525.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDP41525.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 EDP41525.1 - 0.046 13.0 0.1 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GNAT_acetyltr_2 PF13718.1 EDP41526.1 - 4.9e-77 257.6 0.0 9.5e-77 256.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EDP41526.1 - 1e-65 220.6 0.0 3.9e-65 218.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EDP41526.1 - 1e-33 114.8 0.0 2.4e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EDP41526.1 - 7.6e-28 96.5 0.2 2.6e-27 94.8 0.1 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EDP41526.1 - 0.0022 17.9 0.0 0.0077 16.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDP41526.1 - 0.0031 17.6 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NPR3 PF03666.8 EDP41526.1 - 6.6 5.1 10.1 0.99 7.8 0.0 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Transaldolase PF00923.14 EDP41527.1 - 2e-96 322.5 0.3 2.2e-96 322.3 0.2 1.0 1 0 0 1 1 1 1 Transaldolase CorA PF01544.13 EDP41528.1 - 3.7e-11 42.6 3.8 5.4e-11 42.0 2.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GTP_cyclohydroI PF01227.17 EDP41528.1 - 0.18 11.0 0.2 0.79 8.9 0.0 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase I FlaC_arch PF05377.6 EDP41528.1 - 0.56 10.1 5.3 6.8 6.6 1.9 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Adaptin_binding PF10199.4 EDP41529.1 - 0.0041 17.4 0.4 0.048 13.9 0.3 2.2 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF877 PF05943.7 EDP41529.1 - 0.086 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF877) Cyclin PF08613.6 EDP41530.1 - 4.8e-11 43.2 0.0 7.3e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Cyclin RabGAP-TBC PF00566.13 EDP41531.1 - 9e-41 139.6 0.0 1.9e-40 138.6 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Elongin_A PF06881.6 EDP41532.1 - 2.1e-22 79.5 0.1 2.5e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2404 PF10296.4 EDP41533.1 - 0.00052 20.0 0.0 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) WD40 PF00400.27 EDP41535.1 - 5.1e-41 137.1 17.1 3.9e-09 36.0 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat Hira PF07569.6 EDP41535.1 - 9.6e-18 64.1 0.0 3e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 EDP41535.1 - 0.00066 19.1 0.8 0.0018 17.7 0.5 1.8 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 EDP41535.1 - 0.18 11.4 0.3 78 2.8 0.0 3.8 5 0 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EDP41536.1 - 3.8e-27 95.2 0.3 5.1e-27 94.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDP41536.1 - 8.8e-26 91.1 0.0 1.2e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDP41536.1 - 7e-13 48.6 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EDP41536.1 - 0.00068 19.9 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EDP41536.1 - 0.012 15.4 0.5 0.03 14.1 0.1 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EDP41536.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EDP41536.1 - 0.016 13.8 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EDP41536.1 - 0.071 12.1 0.0 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_C PF00137.16 EDP41536.1 - 0.13 12.1 0.4 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 ATP synthase subunit C Lactamase_B PF00753.22 EDP41537.1 - 2.4e-22 79.5 3.2 8.8e-22 77.7 2.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDP41537.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDP41537.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain E3_binding PF02817.12 EDP41537.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 e3 binding domain DUF1977 PF09320.6 EDP41538.1 - 4e-17 62.3 5.3 8.6e-10 38.8 1.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1977) DnaJ PF00226.26 EDP41539.1 - 6.4e-06 25.8 0.1 1.8e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain MIT PF04212.13 EDP41539.1 - 0.066 13.1 0.7 0.066 13.1 0.5 1.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EDP41539.1 - 0.08 12.9 0.3 0.41 10.6 0.2 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.22 EDP41540.1 - 1.9e-66 219.8 3.7 1.8e-23 82.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ChAPs PF09295.5 EDP41541.1 - 1e-139 465.7 0.0 1.4e-139 465.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EDP41541.1 - 1.5e-06 28.4 0.3 0.00091 19.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP41541.1 - 1.1e-05 24.9 0.3 2.4 8.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDP41541.1 - 3.4e-05 23.3 2.5 0.16 11.6 0.0 3.5 3 0 0 3 3 3 2 TPR repeat Apc3 PF12895.2 EDP41541.1 - 0.00021 21.3 3.1 0.084 13.0 0.1 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDP41541.1 - 0.00067 20.0 0.5 58 4.7 0.0 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EDP41541.1 - 0.00074 18.6 0.4 0.21 10.6 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDP41541.1 - 0.57 10.7 3.4 1.3e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EDP41542.1 - 2.9e-37 128.2 37.6 2.9e-37 128.2 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-bind_6 PF13921.1 EDP41543.1 - 4.1e-37 126.0 9.5 4.9e-15 55.3 0.7 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDP41543.1 - 3.7e-34 116.5 9.9 4.2e-12 45.9 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EDP41543.1 - 0.00016 21.5 6.4 0.67 9.8 0.0 3.6 3 1 0 3 3 3 3 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EDP41543.1 - 0.2 11.5 5.3 18 5.3 2.3 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAT PF02259.18 EDP41544.1 - 2.6e-70 237.1 6.8 7.9e-70 235.5 4.6 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EDP41544.1 - 1.7e-19 70.2 0.0 3.6e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_11 PF13414.1 EDP41544.1 - 0.25 11.0 4.9 1.4 8.6 0.0 3.6 3 1 1 4 4 4 0 TPR repeat PI3_PI4_kinase PF00454.22 EDP41546.1 - 2.2e-30 105.8 0.0 6.9e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EDP41546.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.1 EDP41546.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) KAR9 PF08580.5 EDP41546.1 - 0.6 8.3 3.9 1.1 7.4 2.7 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MFS_1 PF07690.11 EDP41547.1 - 3.3e-32 111.5 35.6 3.3e-32 111.5 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Snf7 PF03357.16 EDP41548.1 - 1.7e-39 134.9 17.9 1.7e-39 134.9 12.4 1.6 1 1 1 2 2 2 1 Snf7 MxiH PF09392.5 EDP41548.1 - 0.043 14.3 0.5 0.42 11.1 0.3 2.4 1 1 0 1 1 1 0 Type III secretion needle MxiH like Atg14 PF10186.4 EDP41548.1 - 0.14 11.0 10.9 0.02 13.8 4.7 1.8 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TraF_2 PF13729.1 EDP41548.1 - 0.14 10.9 6.8 0.14 10.9 0.7 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DAO PF01266.19 EDP41549.1 - 4.5e-44 150.8 0.8 5.5e-44 150.5 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDP41549.1 - 0.0017 18.3 0.0 0.0058 16.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDP41549.1 - 0.0088 16.1 0.1 0.087 12.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDP41549.1 - 0.037 14.4 0.1 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EDP41549.1 - 0.057 11.5 0.0 0.089 10.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) BOP1NT PF08145.7 EDP41550.1 - 1.6e-101 339.4 0.7 2.4e-101 338.8 0.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EDP41550.1 - 5.3e-21 73.6 3.8 4.7e-05 23.0 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Proteasome PF00227.21 EDP41552.1 - 9.4e-26 90.2 0.0 1.3e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M28 PF04389.12 EDP41553.1 - 8.1e-16 58.2 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EDP41553.1 - 2.1e-12 46.7 0.0 3.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EDP41553.1 - 1e-08 34.7 0.5 2.5e-08 33.5 0.2 1.7 2 0 0 2 2 2 1 PA domain DUF4463 PF14703.1 EDP41553.1 - 0.0034 17.8 0.0 0.0072 16.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Tmemb_cc2 PF10267.4 EDP41553.1 - 0.023 13.2 0.2 0.11 11.0 0.1 1.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PTRF_SDPR PF15237.1 EDP41553.1 - 0.071 12.5 0.4 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 PTRF/SDPR family Methyltransf_11 PF08241.7 EDP41553.1 - 0.1 13.0 0.1 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Laminin_I PF06008.9 EDP41553.1 - 0.13 11.5 0.4 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Laminin Domain I TBPIP PF07106.8 EDP41553.1 - 0.36 10.3 1.3 0.74 9.3 0.1 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WD40 PF00400.27 EDP41554.1 - 5.8e-52 171.8 10.6 7.5e-10 38.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDP41554.1 - 0.0057 14.8 0.4 5.7 4.9 0.0 3.7 2 1 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDP41554.1 - 0.048 13.1 0.4 6.3 6.1 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain SBDS PF01172.13 EDP41555.1 - 3.4e-14 52.3 0.1 4.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein tRNA-synt_2 PF00152.15 EDP41558.1 - 5.1e-99 331.2 0.0 7.5e-99 330.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDP41558.1 - 1.7e-09 37.3 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain T2SE_Nter PF05157.10 EDP41558.1 - 0.0068 16.4 0.7 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein E, N-terminal domain tRNA-synt_2b PF00587.20 EDP41558.1 - 0.063 12.8 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) cNMP_binding PF00027.24 EDP41559.1 - 5.4e-42 141.5 0.0 3.9e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 EDP41559.1 - 0.029 13.8 0.0 0.078 12.4 0.0 1.8 1 0 0 1 1 1 0 Cupin domain Mt_ATP-synt_D PF05873.7 EDP41560.1 - 5.2e-05 22.9 0.1 5.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CAMP_factor PF07373.6 EDP41560.1 - 0.008 15.6 0.1 0.0096 15.4 0.0 1.1 1 0 0 1 1 1 1 CAMP factor (Cfa) DUF1366 PF07104.6 EDP41560.1 - 0.036 13.6 1.6 0.049 13.2 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) Peptidase_M75 PF09375.5 EDP41560.1 - 0.051 12.8 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 Imelysin DUF1327 PF07041.6 EDP41560.1 - 0.051 13.4 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) DUF2408 PF10303.4 EDP41560.1 - 0.14 12.2 0.3 0.17 12.0 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Ribosomal_S25 PF03297.10 EDP41561.1 - 1.6e-39 134.1 0.7 2.5e-39 133.5 0.5 1.3 1 0 0 1 1 1 1 S25 ribosomal protein Nop14 PF04147.7 EDP41561.1 - 0.015 13.2 0.2 0.019 12.9 0.1 1.1 1 0 0 1 1 1 0 Nop14-like family EF-hand_7 PF13499.1 EDP41562.1 - 1.5e-08 34.6 0.0 1.9e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EDP41562.1 - 1.8e-07 29.9 0.1 1.9e-05 23.6 0.0 2.8 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.1 EDP41562.1 - 3e-07 29.7 0.1 8.3e-06 25.2 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EDP41562.1 - 3.9e-06 26.3 0.3 2.4e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDP41562.1 - 0.0031 16.7 2.2 0.0042 16.3 0.1 2.4 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EDP41562.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 1 0 1 1 1 0 EF-hand domain DUF2956 PF11169.3 EDP41563.1 - 0.083 12.8 2.3 0.15 12.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) IncA PF04156.9 EDP41563.1 - 0.41 10.2 3.5 0.78 9.3 2.4 1.5 1 0 0 1 1 1 0 IncA protein AMMECR1 PF01871.12 EDP41564.1 - 2e-40 137.6 0.0 2.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 RF-1 PF00472.15 EDP41565.1 - 9e-21 73.8 0.1 9e-21 73.8 0.1 2.2 1 1 1 2 2 2 1 RF-1 domain Fork_head PF00250.13 EDP41566.1 - 8.1e-16 57.8 0.0 1.9e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EDP41566.1 - 0.03 14.4 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 FHA domain DUF788 PF05620.6 EDP41567.1 - 8.9e-31 107.0 0.2 1.2e-30 106.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Tmemb_14 PF03647.8 EDP41567.1 - 0.02 15.2 0.8 0.031 14.6 0.3 1.5 1 1 0 1 1 1 0 Transmembrane proteins 14C CbtA PF09490.5 EDP41567.1 - 0.026 13.8 4.4 0.034 13.4 3.1 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Ribosomal_S3Ae PF01015.13 EDP41568.1 - 9.5e-82 273.0 2.4 1.1e-81 272.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EDP41568.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SNF5 PF04855.7 EDP41569.1 - 1.9e-52 178.1 0.0 3.4e-49 167.5 0.0 2.4 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 Sporozoite_P67 PF05642.6 EDP41569.1 - 0.064 11.1 0.7 0.13 10.1 0.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.17 EDP41570.1 - 5.7e-07 29.0 0.0 8.9e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP41570.1 - 0.0005 19.9 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Flavokinase PF01687.12 EDP41572.1 - 1.4e-34 118.6 0.0 1.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Thr_synth_N PF14821.1 EDP41573.1 - 3.4e-27 94.2 0.0 5e-26 90.5 0.0 2.4 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EDP41573.1 - 2.8e-17 62.9 0.0 5e-17 62.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 EDP41574.1 - 1e-16 60.0 8.3 6.1e-09 35.4 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP41574.1 - 0.4 11.0 6.5 8.1 6.8 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain PfkB PF00294.19 EDP41575.1 - 1.6e-34 119.4 0.1 1.9e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RNA_Me_trans PF04252.8 EDP41576.1 - 5.6e-20 71.5 0.0 1.9e-18 66.5 0.0 2.3 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNARE_assoc PF09335.6 EDP41577.1 - 9.4e-11 41.9 8.7 9.4e-11 41.9 6.0 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Sod_Fe_C PF02777.13 EDP41578.1 - 9e-16 57.6 0.0 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDP41578.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.6 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ndc1_Nup PF09531.5 EDP41579.1 - 2e-45 155.3 3.9 2.7e-45 154.9 2.7 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup MCM PF00493.18 EDP41580.1 - 6.9e-133 442.5 0.0 3.7e-130 433.5 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 EDP41580.1 - 1.1e-15 58.1 0.0 6.1e-15 55.7 0.0 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDP41580.1 - 2.9e-07 29.8 0.1 2.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDP41580.1 - 6.4e-07 29.1 0.0 2.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDP41580.1 - 0.011 15.3 0.1 0.079 12.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP41580.1 - 0.11 12.0 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2974 PF11187.3 EDP41582.1 - 0.0026 17.1 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) LIM PF00412.17 EDP41583.1 - 1.9e-28 98.2 34.7 2e-14 53.3 5.4 4.1 3 1 0 3 3 3 3 LIM domain JAB PF01398.16 EDP41584.1 - 1.3e-16 60.3 0.0 6.2e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDP41584.1 - 9.2e-08 31.6 0.2 3.8e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Spc97_Spc98 PF04130.8 EDP41585.1 - 1.3e-100 337.2 0.1 1.7e-100 336.9 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family HTH_24 PF13412.1 EDP41585.1 - 0.11 11.9 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ADH_N PF08240.7 EDP41586.1 - 3e-27 94.5 0.8 4.9e-27 93.8 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP41586.1 - 1.5e-11 43.9 0.1 2.5e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EDP41586.1 - 0.12 10.8 0.1 0.23 9.9 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein Ras PF00071.17 EDP41587.1 - 6.3e-48 162.2 0.5 7.2e-48 162.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP41587.1 - 1e-13 51.7 0.1 1.6e-13 51.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP41587.1 - 3e-08 33.0 0.0 3.6e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDP41587.1 - 5e-06 26.4 0.0 5.9e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDP41587.1 - 3.8e-05 23.1 0.2 0.00072 19.0 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EDP41587.1 - 0.00063 19.0 0.0 0.019 14.2 0.0 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EDP41587.1 - 0.0011 18.2 0.1 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EDP41587.1 - 0.009 15.7 0.1 0.023 14.4 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase CaKB PF03185.10 EDP41587.1 - 0.076 12.3 0.2 0.7 9.2 0.0 2.0 1 1 1 2 2 2 0 Calcium-activated potassium channel, beta subunit Baculo_p74 PF04583.7 EDP41587.1 - 0.076 12.1 0.1 0.36 9.9 0.0 1.8 1 1 1 2 2 2 0 Baculoviridae p74 conserved region AAA_14 PF13173.1 EDP41587.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 EDP41588.1 - 7.6e-07 28.8 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Clat_adaptor_s PF01217.15 EDP41589.1 - 0.00023 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IQ PF00612.22 EDP41590.1 - 2.3e-19 67.0 34.2 0.00076 18.8 0.1 9.5 9 1 0 9 9 9 7 IQ calmodulin-binding motif CH PF00307.26 EDP41590.1 - 4.2e-11 42.8 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EDP41590.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Cu-oxidase_2 PF07731.9 EDP41591.1 - 3.1e-25 88.2 0.5 3.7e-25 88.0 0.4 1.1 1 0 0 1 1 1 1 Multicopper oxidase FH2 PF02181.18 EDP41592.1 - 3.7e-70 236.6 0.2 5.3e-70 236.1 0.2 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain UCR_hinge PF02320.11 EDP41592.1 - 0.15 12.0 0.5 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein ATP-synt_D PF01813.12 EDP41593.1 - 4.1e-62 209.2 0.1 5.5e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Abdominal-A PF12407.3 EDP41594.1 - 0.15 11.6 0.4 0.22 11.0 0.3 1.3 1 0 0 1 1 1 0 Homeobox protein ADK PF00406.17 EDP41595.1 - 2.9e-37 127.8 0.0 1.2e-36 125.8 0.0 1.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EDP41595.1 - 4.1e-11 43.3 0.0 5.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP41595.1 - 1.1e-07 32.6 0.0 1.7e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP41595.1 - 5.8e-07 29.4 0.0 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 EDP41595.1 - 5.7e-05 22.5 0.0 0.00031 20.1 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase Zeta_toxin PF06414.7 EDP41595.1 - 0.026 13.6 0.0 0.05 12.6 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin CLN3 PF02487.12 EDP41596.1 - 2e-51 175.0 3.9 2.6e-51 174.6 2.7 1.2 1 0 0 1 1 1 1 CLN3 protein DUF1656 PF07869.7 EDP41596.1 - 9.9 6.0 9.6 17 5.2 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Snf7 PF03357.16 EDP41597.1 - 4.3e-34 117.3 17.8 7.7e-34 116.5 12.4 1.4 1 1 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.7 EDP41597.1 - 0.094 12.4 7.1 0.15 11.8 4.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.6 EDP41597.1 - 0.3 11.5 5.4 1.8 9.0 0.0 2.9 2 1 0 2 2 2 0 Cytochrome b562 PspA_IM30 PF04012.7 EDP41597.1 - 0.85 8.9 18.6 1.6 8.0 3.6 2.3 1 1 0 2 2 2 0 PspA/IM30 family Resolvase PF00239.16 EDP41597.1 - 1.9 8.3 11.7 0.37 10.6 3.7 2.2 1 1 1 2 2 2 0 Resolvase, N terminal domain DivIC PF04977.10 EDP41597.1 - 7 6.2 6.8 1.6 8.3 0.6 2.6 3 0 0 3 3 3 0 Septum formation initiator YlqD PF11068.3 EDP41597.1 - 7.1 6.6 13.0 5.2 7.1 5.3 2.2 1 1 1 2 2 2 0 YlqD protein Pkinase PF00069.20 EDP41598.1 - 9.2e-44 149.5 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP41598.1 - 1.2e-25 90.1 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP41598.1 - 2.2e-07 30.1 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP41598.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDP41598.1 - 0.0051 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EDP41598.1 - 0.0092 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EDP41598.1 - 0.08 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyto_heme_lyase PF01265.12 EDP41599.1 - 5e-65 219.6 1.2 7.8e-65 219.0 0.8 1.4 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SIS PF01380.17 EDP41600.1 - 6e-14 51.7 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EDP41600.1 - 0.014 15.1 0.4 0.11 12.2 0.1 2.1 1 1 1 2 2 2 0 SIS domain YTH PF04146.10 EDP41601.1 - 4.9e-41 139.6 0.0 5.5e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 YT521-B-like domain Ribosomal_60s PF00428.14 EDP41602.1 - 0.021 15.1 3.8 0.037 14.4 2.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein UCR_Fe-S_N PF10399.4 EDP41602.1 - 0.15 11.2 6.6 0.32 10.2 4.6 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_hydro_9 PF00759.14 EDP41602.1 - 0.32 9.8 1.1 0.51 9.1 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Chorion_2 PF03964.10 EDP41602.1 - 9.3 6.8 10.2 17 5.9 6.5 1.9 1 1 0 1 1 1 0 Chorion family 2 CLASP_N PF12348.3 EDP41603.1 - 2e-13 50.2 0.2 2.6e-06 26.9 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EDP41603.1 - 4.5e-07 29.3 8.7 1.4 9.2 0.2 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EDP41603.1 - 0.0041 17.3 21.1 0.29 11.4 0.0 7.0 5 1 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EDP41603.1 - 0.0087 16.5 18.2 0.8 10.2 0.1 6.0 5 1 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 EDP41603.1 - 0.013 15.3 0.1 18 5.1 0.0 4.1 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EDP41603.1 - 0.073 13.0 2.5 4.2 7.4 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.1 EDP41603.1 - 0.25 11.3 1.5 8.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.3 EDP41604.1 - 7.5e-07 28.7 0.0 7.8e-05 22.1 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 EDP41604.1 - 4.5e-06 26.8 9.1 0.0013 18.9 0.2 5.1 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EDP41604.1 - 5.7e-05 22.8 8.8 0.092 12.8 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat Ipi1_N PF12333.3 EDP41604.1 - 0.074 13.0 0.0 17 5.4 0.0 3.6 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EDP41604.1 - 0.076 13.5 6.8 0.24 11.9 0.1 5.1 4 1 2 6 6 6 0 HEAT-like repeat Transp_cyt_pur PF02133.10 EDP41605.1 - 7e-26 90.7 35.7 2.9e-25 88.7 24.7 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HMGL-like PF00682.14 EDP41606.1 - 5.3e-71 239.0 0.4 5.3e-71 239.0 0.3 1.7 2 0 0 2 2 2 1 HMGL-like Dus PF01207.12 EDP41607.1 - 2.6e-38 131.6 0.0 3.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) EPSP_synthase PF00275.15 EDP41608.1 - 2.1e-121 405.3 0.2 3.5e-121 404.5 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EDP41608.1 - 7e-95 316.8 0.8 2.2e-94 315.2 0.2 1.9 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EDP41608.1 - 3.9e-58 196.7 0.0 1.4e-57 194.9 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 EDP41608.1 - 2.6e-26 92.3 0.0 5.1e-24 84.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EDP41608.1 - 1.2e-24 86.1 0.0 4.2e-24 84.4 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EDP41608.1 - 8.3e-14 51.8 0.0 2.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EDP41608.1 - 1.5e-08 34.2 0.6 4.5e-08 32.6 0.1 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.1 EDP41608.1 - 0.00059 19.7 0.0 0.008 16.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDP41608.1 - 0.0027 18.5 0.0 0.0068 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP41608.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EDP41608.1 - 0.5 9.3 0.0 0.86 8.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_membrane PF00664.18 EDP41609.1 - 3.2e-42 144.8 3.3 3.2e-42 144.8 2.3 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDP41609.1 - 3.8e-32 111.4 0.0 7.8e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EDP41609.1 - 9.3e-05 21.6 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.14 EDP41609.1 - 0.0014 17.8 0.1 0.017 14.3 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP41609.1 - 0.0021 18.1 0.0 0.0071 16.3 0.0 1.6 1 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EDP41609.1 - 0.0073 14.9 0.1 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EDP41609.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDP41609.1 - 0.043 13.8 0.6 0.18 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain CDP-OH_P_transf PF01066.16 EDP41610.1 - 1.9e-15 57.0 5.2 1.9e-15 57.0 3.6 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4395 PF14340.1 EDP41610.1 - 0.0093 16.0 1.6 0.019 15.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) Hexapep PF00132.19 EDP41611.1 - 5.6e-12 44.5 1.4 3.5e-05 23.1 0.1 3.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDP41611.1 - 2.6e-05 23.6 6.5 0.0068 15.9 3.7 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EDP41611.1 - 0.0085 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EDP41611.1 - 0.022 14.8 0.4 0.14 12.2 0.2 2.1 1 1 0 1 1 1 0 MobA-like NTP transferase domain MIF4G PF02854.14 EDP41612.1 - 5e-32 111.0 0.0 6.7e-19 68.1 0.0 3.6 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 EDP41612.1 - 1.2e-05 25.1 31.3 1.2e-05 25.1 21.7 3.6 2 1 1 3 3 3 1 Up-frameshift suppressor 2 KH_1 PF00013.24 EDP41613.1 - 4e-40 135.2 7.0 9.8e-15 53.9 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDP41613.1 - 2.3e-29 100.4 16.1 2.3e-10 39.8 0.3 3.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EDP41613.1 - 1.6e-14 53.1 8.0 5.9e-06 25.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDP41613.1 - 1.1e-07 31.3 3.8 0.12 12.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDP41613.1 - 0.00073 19.2 3.6 2 8.2 0.1 3.6 3 0 0 3 3 3 2 NusA-like KH domain UDPGT PF00201.13 EDP41614.1 - 7.7e-09 34.6 0.0 6.8e-08 31.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EDP41614.1 - 0.12 12.1 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain p450 PF00067.17 EDP41615.1 - 2e-61 207.9 0.2 5.2e-54 183.4 0.1 2.4 2 1 0 2 2 2 2 Cytochrome P450 PAS_3 PF08447.6 EDP41615.1 - 0.1 12.7 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 PAS fold dUTPase PF00692.14 EDP41616.1 - 9.2e-44 148.0 0.0 1.1e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase Pro_isomerase PF00160.16 EDP41617.1 - 7.6e-39 133.4 0.0 1.8e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LMWPc PF01451.16 EDP41617.1 - 0.0027 18.0 0.3 0.0045 17.3 0.2 1.5 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase RhoGAP PF00620.22 EDP41618.1 - 1.2e-33 115.8 0.3 2.6e-33 114.7 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain Ran_BP1 PF00638.13 EDP41619.1 - 1e-21 77.1 1.2 1.8e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 EDP41619.1 - 1.6e-07 30.9 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 WH1 domain Daxx PF03344.10 EDP41619.1 - 6.7 5.0 26.2 8.2 4.7 18.2 1.1 1 0 0 1 1 1 0 Daxx Family Usp PF00582.21 EDP41620.1 - 4.9e-16 59.1 0.2 1.8e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Lon_C PF05362.8 EDP41621.1 - 4.3e-67 225.3 0.4 7.9e-67 224.5 0.1 1.5 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EDP41621.1 - 2e-34 119.0 0.1 2e-34 119.0 0.0 1.7 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EDP41621.1 - 1.9e-21 76.6 0.0 5.5e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EDP41621.1 - 1e-07 31.5 0.0 2.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EDP41621.1 - 4.3e-06 26.5 0.0 8.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EDP41621.1 - 8e-06 24.7 0.0 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.9 EDP41621.1 - 4.1e-05 23.5 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EDP41621.1 - 5.7e-05 23.9 0.0 0.00018 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDP41621.1 - 7e-05 22.8 0.1 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDP41621.1 - 8e-05 22.7 0.0 0.0019 18.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP41621.1 - 0.00066 18.7 0.0 0.004 16.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDP41621.1 - 0.00091 19.1 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP41621.1 - 0.0016 18.7 2.0 0.0032 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDP41621.1 - 0.0019 16.9 0.3 0.27 9.8 0.1 2.3 2 0 0 2 2 2 1 TIP49 C-terminus ClpB_D2-small PF10431.4 EDP41621.1 - 0.0023 17.7 0.7 0.013 15.4 0.1 2.6 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein SKI PF01202.17 EDP41621.1 - 0.0076 16.1 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase DUF258 PF03193.11 EDP41621.1 - 0.028 13.6 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EDP41621.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EDP41621.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EDP41621.1 - 0.042 13.5 0.1 0.48 10.1 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 EDP41621.1 - 0.043 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EDP41621.1 - 0.051 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EDP41621.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDP41621.1 - 0.059 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EDP41621.1 - 0.077 12.9 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EDP41621.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol_B PF00136.16 EDP41622.1 - 3.7e-147 490.8 0.6 5.3e-147 490.3 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDP41622.1 - 4.4e-86 288.7 0.0 2.5e-85 286.2 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDP41622.1 - 5.7e-19 67.9 10.5 1.3e-18 66.7 7.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EDP41622.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EDP41622.1 - 0.022 14.5 0.2 0.08 12.7 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily DUF1476 PF07345.6 EDP41622.1 - 0.16 12.2 0.6 9.3 6.5 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) DNA_pol_B_2 PF03175.8 EDP41622.1 - 0.36 9.4 6.2 0.97 8.0 1.9 2.7 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral Nol1_Nop2_Fmu PF01189.12 EDP41623.1 - 3e-90 302.4 0.0 8.1e-90 301.0 0.0 1.7 2 0 0 2 2 2 1 NOL1/NOP2/sun family Met_10 PF02475.11 EDP41623.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 EDP41623.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase CNH PF00780.17 EDP41624.1 - 3.1e-77 259.6 0.0 4.7e-77 259.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EDP41624.1 - 1.1e-46 158.1 0.0 2.4e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EDP41624.1 - 2.6e-36 125.1 0.3 4e-36 124.5 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EDP41624.1 - 1.7e-05 24.5 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF221 PF02714.10 EDP41625.1 - 1.2e-66 224.8 28.2 1.2e-66 224.8 19.5 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDP41625.1 - 3.1e-15 56.0 1.3 3.1e-15 56.0 0.9 3.6 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDP41625.1 - 2.9e-08 34.0 0.2 1.2e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) YjeF_N PF03853.10 EDP41626.1 - 1.4e-32 112.6 0.0 1.7e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox_3 PF13738.1 EDP41627.1 - 1.8e-23 83.6 0.0 1.5e-20 74.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDP41627.1 - 2.1e-19 69.1 0.1 1.1e-18 66.7 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EDP41627.1 - 2.6e-12 47.0 0.0 5.3e-09 36.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP41627.1 - 1.3e-10 41.1 0.3 5.3e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDP41627.1 - 2.8e-10 39.6 0.2 5.1e-06 25.6 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EDP41627.1 - 3.6e-10 40.1 2.2 0.00038 20.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDP41627.1 - 2.4e-09 36.5 0.0 2.3e-07 30.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDP41627.1 - 8.6e-08 32.0 0.2 2.5e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EDP41627.1 - 0.00012 22.2 0.3 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EDP41627.1 - 0.00013 20.5 1.0 0.012 14.0 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 EDP41627.1 - 0.00017 20.8 0.0 0.0058 15.7 0.0 2.4 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EDP41627.1 - 0.00021 20.9 0.9 0.00045 19.9 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EDP41627.1 - 0.00026 20.1 0.1 0.015 14.3 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EDP41627.1 - 0.00072 18.7 2.5 0.053 12.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 EDP41627.1 - 0.0029 17.0 0.1 0.0049 16.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EDP41627.1 - 0.013 15.7 0.0 6 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EDP41627.1 - 0.013 14.3 1.4 0.25 10.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_2 PF03446.10 EDP41627.1 - 0.024 14.4 0.4 0.044 13.6 0.0 1.5 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.7 EDP41627.1 - 0.026 13.4 0.1 0.2 10.5 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDP41627.1 - 0.027 13.3 0.0 0.027 13.3 0.0 1.5 2 0 0 2 2 1 0 FAD binding domain TrkA_N PF02254.13 EDP41627.1 - 0.061 13.3 0.5 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 EDP41627.1 - 0.069 13.1 0.1 0.069 13.1 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 EDP41627.1 - 0.086 12.5 0.1 0.086 12.5 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EDP41627.1 - 0.19 10.7 0.2 0.64 9.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDP41627.1 - 0.36 10.3 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain GATA PF00320.22 EDP41628.1 - 3.6e-14 51.8 7.9 1.9e-13 49.5 5.2 2.4 2 0 0 2 2 2 1 GATA zinc finger PQ-loop PF04193.9 EDP41629.1 - 1.6e-13 50.0 2.4 1.6e-13 50.0 1.7 1.8 2 0 0 2 2 2 1 PQ loop repeat DUF1301 PF06979.7 EDP41629.1 - 0.0057 16.8 1.2 0.07 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1301) DUF4063 PF13272.1 EDP41629.1 - 0.068 12.9 0.8 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) PH PF00169.24 EDP41630.1 - 0.0039 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DNA_pol_A PF00476.15 EDP41631.1 - 2.2e-87 293.1 0.0 3.7e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Brr6_like_C_C PF10104.4 EDP41632.1 - 1.1e-39 135.0 0.1 1.3e-39 134.7 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Y_phosphatase2 PF03162.8 EDP41633.1 - 1e-26 93.2 0.0 1e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDP41633.1 - 0.018 15.3 0.0 0.13 12.4 0.0 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family Sad1_UNC PF07738.8 EDP41634.1 - 4.5e-27 94.4 0.0 5e-25 87.8 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal IncA PF04156.9 EDP41634.1 - 0.0002 21.0 0.9 0.0002 21.0 0.6 2.6 2 1 1 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 EDP41634.1 - 0.086 12.0 0.8 0.24 10.5 0.5 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Herpes_UL73 PF03554.8 EDP41634.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Spc7 PF08317.6 EDP41634.1 - 0.23 10.1 8.0 0.017 13.8 1.6 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EDP41634.1 - 0.42 10.3 4.9 12 5.6 0.1 3.1 3 0 0 3 3 3 0 Laminin Domain II Tropomyosin_1 PF12718.2 EDP41634.1 - 0.46 10.3 16.2 0.02 14.7 6.1 2.2 2 0 0 2 2 2 0 Tropomyosin like PCEMA1 PF07418.6 EDP41634.1 - 1 8.6 5.5 0.37 10.1 0.1 2.6 3 0 0 3 3 3 0 Acidic phosphoprotein precursor PCEMA1 Aldo_ket_red PF00248.16 EDP41635.1 - 4.3e-51 173.4 0.0 5e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SHR3_chaperone PF08229.6 EDP41636.1 - 1.3e-31 109.1 6.0 2.7e-31 108.0 4.2 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 DBD_Tnp_Mut PF03108.10 EDP41637.1 - 2.6e-05 23.6 0.0 0.00022 20.7 0.0 2.3 3 0 0 3 3 3 1 MuDR family transposase MULE PF10551.4 EDP41637.1 - 0.0051 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC_2 PF13696.1 EDP41637.1 - 0.0068 15.8 4.8 0.066 12.7 0.7 2.6 2 0 0 2 2 2 1 Zinc knuckle SWIM PF04434.12 EDP41637.1 - 0.0097 15.3 0.3 0.029 13.8 0.2 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_6 PF15288.1 EDP41637.1 - 0.37 10.4 6.8 0.064 12.9 0.9 2.6 2 0 0 2 2 2 0 Zinc knuckle Helicase_C_3 PF13625.1 EDP41638.1 - 3.3e-27 94.7 0.0 1e-26 93.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP41638.1 - 3.3e-15 56.4 0.0 7.2e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDP41638.1 - 1.9e-13 49.9 0.1 3.3e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP41638.1 - 2.8e-11 43.1 0.1 7.1e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MSP1_C PF07462.6 EDP41638.1 - 0.029 12.7 0.8 0.042 12.2 0.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dynactin_p62 PF05502.8 EDP41639.1 - 3.1e-57 194.4 27.5 1.2e-40 139.7 8.7 3.0 1 1 1 3 3 3 3 Dynactin p62 family AIP3 PF03915.8 EDP41640.1 - 1.5e-103 347.0 1.9 2.1e-103 346.4 1.3 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 EDP41641.1 - 0.0073 16.3 0.1 0.009 16.0 0.1 1.2 1 0 0 1 1 1 1 Syntaxin-like protein Trp_repressor PF01371.14 EDP41641.1 - 0.075 12.9 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Trp repressor protein DUF3336 PF11815.3 EDP41642.1 - 3.1e-37 127.3 0.5 6e-37 126.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDP41642.1 - 5.1e-20 72.2 0.0 9.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase XRN_N PF03159.13 EDP41643.1 - 1.8e-74 250.1 0.0 1.8e-74 250.1 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PAPS_reduct PF01507.14 EDP41644.1 - 6.7e-19 68.3 0.0 1.1e-08 35.1 0.0 3.1 2 1 1 3 3 3 3 Phosphoadenosine phosphosulfate reductase family HCV_env PF01539.12 EDP41645.1 - 0.0052 16.2 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 Nop16 PF09420.5 EDP41646.1 - 6.9e-32 110.8 0.2 8.2e-32 110.5 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pkinase PF00069.20 EDP41647.1 - 1.8e-20 73.2 0.0 1.3e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EDP41647.1 - 1.3e-18 65.3 3.7 0.0008 19.2 0.0 6.6 6 0 0 6 6 6 5 HEAT repeat WD40 PF00400.27 EDP41647.1 - 6.3e-15 54.4 22.9 5.5e-09 35.5 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EDP41647.1 - 8.7e-11 41.3 0.0 0.0008 18.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase HEAT_2 PF13646.1 EDP41647.1 - 3.4e-09 36.8 0.0 0.0096 16.1 0.0 3.5 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EDP41647.1 - 3.9e-05 24.0 0.4 0.15 12.5 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 EDP41647.1 - 0.029 12.6 3.9 0.082 11.2 2.7 1.7 1 1 0 1 1 1 0 Adaptin N terminal region Arm PF00514.18 EDP41647.1 - 0.057 13.2 0.3 26 4.8 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Actin PF00022.14 EDP41648.1 - 1.8e-89 299.8 0.0 7.8e-88 294.5 0.0 2.0 1 1 0 1 1 1 1 Actin Robl_LC7 PF03259.12 EDP41648.1 - 0.068 12.7 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain Acetyltransf_1 PF00583.19 EDP41649.1 - 5.2e-12 45.6 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EDP41649.1 - 6.7e-06 26.0 0.0 9.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDP41649.1 - 2.2e-05 24.1 0.1 9.3e-05 22.1 0.1 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EDP41649.1 - 5.1e-05 23.4 0.0 6.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDP41649.1 - 9.3e-05 22.5 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDP41649.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PRMT5 PF05185.11 EDP41650.1 - 7.1e-135 450.3 0.0 9.2e-135 450.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EDP41650.1 - 0.00013 22.4 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP41650.1 - 0.0084 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41650.1 - 0.045 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.3 EDP41650.1 - 0.091 11.6 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RRM_1 PF00076.17 EDP41651.1 - 1.8e-18 65.9 0.3 4.2e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP41651.1 - 8.8e-15 54.4 0.0 2.5e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP41651.1 - 8e-10 38.4 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CS PF04969.11 EDP41652.1 - 1.2e-06 28.9 0.0 2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 CS domain SIN1 PF05422.7 EDP41653.1 - 3e-07 29.3 0.0 3.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) Aconitase PF00330.15 EDP41654.1 - 2.1e-170 567.2 0.1 6.3e-170 565.6 0.1 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDP41654.1 - 2.5e-45 153.7 0.0 4.9e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pyr_redox_2 PF07992.9 EDP41655.1 - 1.8e-26 93.2 0.1 2.2e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDP41655.1 - 2e-16 60.1 0.2 1.2e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP41655.1 - 3.9e-07 30.3 0.1 0.00069 19.7 0.0 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDP41655.1 - 3.5e-05 23.0 0.7 0.0004 19.5 0.0 2.5 2 1 1 3 3 3 1 Thi4 family GIDA PF01134.17 EDP41655.1 - 6.8e-05 21.8 1.7 0.0053 15.6 0.0 3.2 4 1 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EDP41655.1 - 0.00031 20.7 0.4 0.0034 17.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDP41655.1 - 0.00075 18.6 2.1 0.15 11.1 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase DAO PF01266.19 EDP41655.1 - 0.001 18.0 0.1 0.0028 16.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EDP41655.1 - 0.0014 18.8 0.2 0.089 13.0 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDP41655.1 - 0.0023 18.0 0.1 0.95 9.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EDP41655.1 - 0.004 16.0 2.9 0.021 13.6 0.5 2.3 2 1 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 EDP41655.1 - 0.0075 15.2 0.1 0.5 9.2 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EDP41655.1 - 0.011 14.4 0.2 0.046 12.3 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EDP41655.1 - 0.018 14.1 0.1 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EDP41655.1 - 0.024 13.1 0.3 0.093 11.1 0.3 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EDP41655.1 - 0.13 11.9 0.1 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus COesterase PF00135.23 EDP41656.1 - 1.2e-68 232.1 4.3 1.5e-66 225.2 0.3 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EDP41656.1 - 0.0085 15.6 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_L4 PF00573.17 EDP41657.1 - 4.4e-44 150.1 0.4 7.9e-44 149.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EDP41657.1 - 6.3e-28 96.4 0.8 6.3e-28 96.4 0.6 2.7 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain PAPS_reduct PF01507.14 EDP41658.1 - 6.2e-40 136.8 0.0 7.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Orbi_VP6 PF01516.11 EDP41658.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF3395 PF11875.3 EDP41659.1 - 3.1e-35 121.0 0.1 7.8e-35 119.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EDP41659.1 - 1.6e-10 40.5 0.7 2.8e-10 39.7 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain LSM PF01423.17 EDP41660.1 - 3.2e-06 26.6 0.0 3.5e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain Redoxin PF08534.5 EDP41661.1 - 1.5e-31 108.8 0.0 1.7e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDP41661.1 - 2.7e-10 40.0 0.0 3.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Rap_GAP PF02145.10 EDP41662.1 - 5.6e-48 162.8 0.0 1.2e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 EDP41662.1 - 6.7e-33 113.8 0.0 9.9e-32 109.9 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 EDP41662.1 - 1.8e-32 112.8 7.7 1.8e-30 106.2 5.3 3.2 1 1 0 1 1 1 1 Tuberin HAD_2 PF13419.1 EDP41663.1 - 5.5e-22 78.8 0.1 2.1e-21 76.9 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDP41663.1 - 0.00029 21.3 0.0 0.00033 21.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDP41663.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_hydro_47 PF01532.15 EDP41664.1 - 5.3e-143 476.9 0.0 6.5e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LRR_6 PF13516.1 EDP41665.1 - 6.4e-11 41.1 14.2 2.7 8.3 0.0 8.6 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.2 EDP41665.1 - 5.5e-08 32.2 8.1 0.0055 16.3 0.0 5.8 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDP41665.1 - 7.1e-05 22.3 13.0 1.9 8.8 0.1 8.4 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EDP41665.1 - 0.0014 18.2 12.9 2.4 7.9 0.1 5.6 4 2 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 EDP41665.1 - 2.4 8.7 16.8 61 4.4 0.0 7.0 7 0 0 7 7 7 0 Leucine rich repeat DUF2454 PF10521.4 EDP41666.1 - 0.0063 15.5 0.1 14 4.5 0.0 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) HEAT PF02985.17 EDP41666.1 - 4.6 7.5 13.2 5.4 7.3 0.1 6.7 6 0 0 6 6 6 0 HEAT repeat UCH PF00443.24 EDP41667.1 - 8.7e-35 120.1 0.1 1.2e-34 119.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EDP41667.1 - 1.9e-18 65.6 0.1 1.9e-16 59.2 0.0 2.7 2 0 0 2 2 2 1 A repeated domain in UCH-protein UCH_1 PF13423.1 EDP41667.1 - 2e-10 40.6 0.0 4.1e-08 33.0 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 EDP41667.1 - 1.5 8.3 9.7 14 5.1 5.0 2.4 2 0 0 2 2 2 0 IncA protein Rer1 PF03248.8 EDP41668.1 - 1.1e-65 220.5 2.8 1.4e-65 220.2 1.9 1.0 1 0 0 1 1 1 1 Rer1 family 2TM PF13239.1 EDP41668.1 - 2.1 8.4 5.0 10 6.2 0.7 2.4 2 0 0 2 2 2 0 2TM domain Cupin_8 PF13621.1 EDP41669.1 - 3.5e-32 111.8 0.0 1.4e-31 109.8 0.0 1.5 1 1 1 2 2 2 1 Cupin-like domain Nop25 PF09805.4 EDP41669.1 - 0.099 12.7 7.5 0.094 12.7 3.8 1.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.7 EDP41669.1 - 9.1 5.4 14.8 0.74 9.0 6.9 1.5 2 0 0 2 2 2 0 NOA36 protein LIP PF03583.9 EDP41670.1 - 8.1e-61 205.7 0.6 1.1e-60 205.3 0.4 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EDP41670.1 - 3.6e-06 27.0 0.1 1e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP41670.1 - 7.9e-05 22.4 1.0 0.00024 20.8 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDP41670.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EDP41670.1 - 0.039 13.2 0.2 9.1 5.4 0.0 3.1 2 1 1 3 3 3 0 Dienelactone hydrolase family LIP PF03583.9 EDP41671.1 - 4.4e-65 219.7 0.0 5.4e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EDP41671.1 - 0.00023 20.9 0.1 0.00063 19.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP41671.1 - 0.0015 18.5 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDP41671.1 - 0.084 12.3 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Asp PF00026.18 EDP41672.1 - 1.7e-50 172.1 1.4 5.2e-50 170.4 0.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP41672.1 - 1.2e-08 35.2 0.1 0.00023 21.6 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EDP41672.1 - 8.2e-05 22.6 0.1 0.00076 19.4 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EDP41672.1 - 0.054 13.3 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 EDP41672.1 - 0.099 12.1 0.0 0.71 9.4 0.0 2.4 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal LIP PF03583.9 EDP41673.1 - 4.4e-62 209.9 0.0 5.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EDP41673.1 - 8.3e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDP41673.1 - 0.00024 20.3 0.5 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDP41673.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDP41673.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cu-oxidase_3 PF07732.10 EDP41674.1 - 8.4e-18 64.2 0.0 9.9e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Arr-ms PF12120.3 EDP41674.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Rifampin ADP-ribosyl transferase RQC PF09382.5 EDP41676.1 - 2.6e-20 72.1 0.1 5.6e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 EDP41676.1 - 4.6e-20 71.7 0.0 9.6e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP41676.1 - 5.5e-18 64.6 0.0 3.2e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 6PGD PF00393.14 EDP41677.1 - 5.6e-132 439.3 0.0 6.8e-132 439.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDP41677.1 - 1.3e-53 181.2 0.0 1.9e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDP41677.1 - 0.019 15.3 0.1 0.042 14.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EDP41677.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_1 PF00515.23 EDP41678.1 - 6.4e-29 98.3 1.2 1.3e-08 34.0 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDP41678.1 - 1.9e-27 94.6 4.9 8.3e-20 70.2 1.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDP41678.1 - 1.3e-21 74.7 1.3 3.2e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDP41678.1 - 2.6e-15 55.2 0.9 6.1e-07 29.1 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP41678.1 - 9.3e-14 50.0 1.5 0.00045 19.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP41678.1 - 3.4e-13 48.9 0.2 7.1e-05 23.0 0.0 4.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDP41678.1 - 2.1e-12 47.3 0.5 1.5e-06 28.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP41678.1 - 1.8e-11 43.8 2.3 4.2e-08 33.0 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP41678.1 - 1.7e-09 36.7 0.4 7.4e-05 22.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP41678.1 - 2.2e-09 37.5 0.2 1.4e-05 25.3 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP41678.1 - 1.3e-06 28.1 0.0 0.00016 21.4 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EDP41678.1 - 1e-05 25.9 0.1 5.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 EDP41678.1 - 3.3e-05 23.1 0.1 7.8e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EDP41678.1 - 6.4e-05 23.0 1.4 0.0076 16.3 0.4 2.2 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDP41678.1 - 0.0002 21.2 2.1 0.96 9.4 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDP41678.1 - 0.0013 19.0 3.3 1.2 9.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDP41678.1 - 0.0084 16.4 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EDP41678.1 - 0.078 12.8 5.0 2.3 8.1 0.2 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 EDP41678.1 - 0.2 11.4 2.0 4.1 7.2 0.1 3.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Sterol-sensing PF12349.3 EDP41679.1 - 3e-36 124.1 10.3 6e-36 123.2 7.1 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EDP41679.1 - 5.4e-10 37.8 8.1 7.7e-10 37.3 5.6 1.1 1 0 0 1 1 1 1 Patched family Rad21_Rec8_N PF04825.8 EDP41681.1 - 1.6e-32 111.7 0.0 3.1e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDP41681.1 - 2.1e-10 39.5 0.0 3.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EDP41681.1 - 0.0072 15.9 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 ScpA/B protein Aa_trans PF01490.13 EDP41682.1 - 1.4e-44 152.1 12.7 9.3e-44 149.5 6.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF2371 PF10177.4 EDP41682.1 - 0.19 11.5 2.3 16 5.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Aa_trans PF01490.13 EDP41683.1 - 6e-12 44.7 0.7 7e-12 44.5 0.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EDP41683.1 - 0.00078 18.3 1.8 0.00098 18.0 1.3 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family RhoGAP PF00620.22 EDP41684.1 - 3.8e-37 127.2 0.1 7.2e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EDP41684.1 - 6.8e-29 99.7 31.2 1.3e-13 50.7 2.3 4.9 5 0 0 5 5 5 4 LIM domain F-box-like PF12937.2 EDP41685.1 - 1.8e-05 24.3 1.2 4.8e-05 22.9 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDP41685.1 - 0.0016 18.0 2.7 0.015 14.9 0.4 2.5 2 0 0 2 2 2 1 F-box domain Cytomega_US3 PF05963.6 EDP41685.1 - 0.055 12.7 0.1 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus US3 protein Ank_2 PF12796.2 EDP41686.1 - 1.7e-12 47.5 4.2 1.8e-06 28.1 0.0 4.3 2 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP41686.1 - 5.4e-10 39.5 6.5 0.00065 20.1 0.1 4.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 EDP41686.1 - 6.7e-10 38.2 8.8 5e-06 26.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EDP41686.1 - 1.6e-08 33.9 5.3 0.00032 20.6 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EDP41686.1 - 8.1e-08 32.2 11.9 1.8e-05 24.8 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EDP41686.1 - 7.7e-05 22.2 0.0 0.00034 20.1 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Mnd1 PF03962.10 EDP41686.1 - 1.2 8.7 5.0 1.3 8.6 2.0 1.9 2 0 0 2 2 2 0 Mnd1 family Spc7 PF08317.6 EDP41686.1 - 1.7 7.2 4.9 1 7.9 1.6 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Sporozoite_P67 PF05642.6 EDP41686.1 - 4.3 5.0 12.6 8.3 4.1 8.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SH3_1 PF00018.23 EDP41687.1 - 1.4e-41 139.6 1.2 7.5e-14 50.8 0.0 3.8 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EDP41687.1 - 1.9e-36 123.4 6.0 1e-11 44.2 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EDP41687.1 - 4.1e-22 77.4 0.0 9e-08 31.4 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 EDP41687.1 - 8.6e-17 60.5 0.0 1.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_3 PF08239.6 EDP41687.1 - 0.00083 19.4 0.4 8.2 6.7 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_1 PF00536.25 EDP41687.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) START PF01852.14 EDP41688.1 - 3.4e-13 49.3 1.8 0.00018 20.8 0.0 3.4 3 0 0 3 3 3 3 START domain SelP_N PF04592.9 EDP41688.1 - 0.74 9.1 7.4 1.9 7.7 5.1 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Corona_nucleoca PF00937.13 EDP41688.1 - 1.3 7.8 24.9 0.023 13.6 2.5 2.6 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein Serinc PF03348.10 EDP41688.1 - 1.4 7.5 2.1 3.3 6.3 1.4 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.8 EDP41688.1 - 4.6 7.3 32.4 0.051 13.6 5.2 4.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.10 EDP41688.1 - 5.9 6.4 6.1 11 5.5 4.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Mak16 PF04874.9 EDP41689.1 - 4.5e-21 74.8 26.6 2.7e-20 72.3 10.8 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 EDP41689.1 - 0.062 12.7 0.7 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Conserved carboxylase domain Pkinase PF00069.20 EDP41690.1 - 9.2e-47 159.3 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP41690.1 - 2.3e-42 144.8 0.0 2.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP41690.1 - 0.021 14.5 0.0 0.051 13.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nitroreductase PF00881.19 EDP41691.1 - 7e-19 68.2 0.0 8.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.19 EDP41692.1 - 2e-10 40.7 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Cyclin PF08613.6 EDP41694.1 - 2.2e-21 76.8 0.4 2.6e-21 76.5 0.3 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDP41694.1 - 0.0034 16.9 0.6 0.0043 16.6 0.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Prp18 PF02840.10 EDP41695.1 - 4.3e-31 107.6 0.2 8.4e-31 106.7 0.0 1.5 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EDP41695.1 - 7.3e-13 47.5 3.1 1.6e-12 46.4 2.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like LcrG PF07216.7 EDP41695.1 - 0.16 12.0 1.8 0.28 11.2 0.2 2.2 2 1 0 2 2 2 0 LcrG protein Transformer PF06495.6 EDP41695.1 - 0.84 9.4 7.4 1.5 8.6 5.2 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein COX6B PF02297.12 EDP41696.1 - 1.1e-15 57.4 5.7 1.3e-15 57.1 3.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EDP41696.1 - 0.02 14.8 0.5 0.056 13.3 0.4 1.8 1 1 0 1 1 1 0 CHCH domain FANCL_C PF11793.3 EDP41696.1 - 0.25 11.3 2.6 0.88 9.5 1.9 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain Med1 PF10744.4 EDP41697.1 - 0.049 12.3 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 DAGK_cat PF00781.19 EDP41699.1 - 1.8e-11 43.5 0.0 3.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EDP41699.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Methyltransf_23 PF13489.1 EDP41700.1 - 7.3e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EDP41700.1 - 6.3e-05 23.7 0.3 0.00015 22.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41700.1 - 0.00012 22.4 0.0 0.00045 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP41700.1 - 0.0032 17.9 0.0 0.0093 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41700.1 - 0.033 14.7 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LEA_2 PF03168.8 EDP41701.1 - 0.00059 20.1 0.0 0.00098 19.4 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF3753 PF12575.3 EDP41701.1 - 0.17 11.6 1.8 0.36 10.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Cpn60_TCP1 PF00118.19 EDP41702.1 - 1.1e-142 476.1 10.6 1.4e-142 475.7 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UFD1 PF03152.9 EDP41703.1 - 9.4e-54 181.2 0.0 3.2e-51 172.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Methyltransf_6 PF03737.10 EDP41704.1 - 3.9e-19 69.0 0.0 8.5e-18 64.6 0.0 2.2 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase DUF3808 PF10300.4 EDP41705.1 - 7.9e-67 225.8 0.1 1.4e-66 224.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EDP41705.1 - 4.6e-07 29.3 10.0 0.00017 21.1 1.2 4.0 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EDP41705.1 - 5.1e-06 25.8 8.5 0.21 11.2 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP41705.1 - 5.9e-05 22.6 18.0 0.0061 16.3 0.7 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP41705.1 - 0.00016 21.5 6.6 0.21 11.5 0.4 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP41705.1 - 0.0029 17.3 5.4 5.3 7.0 0.3 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP41705.1 - 0.017 14.8 4.4 13 5.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDP41705.1 - 0.047 14.3 0.6 8.2 7.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BaffR-Tall_bind PF09256.5 EDP41705.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding TPR_19 PF14559.1 EDP41705.1 - 0.073 13.4 0.3 27 5.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP41705.1 - 0.083 13.5 0.2 24 5.9 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP41705.1 - 0.16 12.5 0.7 30 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDP41705.1 - 0.2 11.9 1.5 0.6 10.4 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP41705.1 - 2.7 8.2 9.1 0.64 10.1 1.1 3.0 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CRAL_TRIO PF00650.15 EDP41706.1 - 2e-31 108.6 0.0 3.2e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EDP41706.1 - 1.3e-12 47.8 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDP41706.1 - 4e-08 33.2 0.0 1.5e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mito_fiss_reg PF05308.6 EDP41707.1 - 2.7 7.2 9.2 0.12 11.7 2.5 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Abhydrolase_1 PF00561.15 EDP41709.1 - 3.7e-20 72.4 0.0 1e-15 57.9 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDP41709.1 - 2.2e-11 44.0 1.6 3.4e-10 40.2 1.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDP41709.1 - 0.0039 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EDP41709.1 - 0.03 14.0 0.0 0.46 10.2 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_His PF13393.1 EDP41710.1 - 2.3e-38 132.0 3.5 4.5e-34 117.9 0.0 2.5 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EDP41710.1 - 2.2e-18 66.4 0.0 3.8e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP41710.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDP41710.1 - 0.002 16.9 1.8 0.19 10.4 0.3 2.9 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Use1 PF09753.4 EDP41711.1 - 1.2e-10 41.3 0.0 1.6e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 Ribonuc_L-PSP PF01042.16 EDP41712.1 - 1.1e-41 141.3 0.3 1.4e-41 140.9 0.2 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP RhoGEF PF00621.15 EDP41713.1 - 1.1e-13 51.5 0.6 2.2e-12 47.1 0.4 2.3 1 1 0 1 1 1 1 RhoGEF domain Ndufs5 PF10200.4 EDP41714.1 - 0.00087 19.2 1.4 0.0016 18.3 1.0 1.5 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EDP41714.1 - 0.0021 18.1 0.4 0.003 17.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 EDP41714.1 - 0.024 14.6 1.0 0.044 13.8 0.7 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EDP41714.1 - 0.028 14.1 3.8 0.069 12.9 2.6 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EDP41714.1 - 0.38 10.8 0.1 0.38 10.8 0.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Gpi1 PF05024.10 EDP41715.1 - 1.7e-37 128.9 9.7 3.2e-37 128.0 6.7 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.17 EDP41716.1 - 1.4e-58 196.8 0.1 1.9e-58 196.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP41716.1 - 4.8e-20 72.2 0.0 7.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP41716.1 - 7.4e-16 57.8 0.1 9.3e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDP41716.1 - 8.8e-07 28.5 0.0 4.7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDP41716.1 - 2.3e-05 23.6 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDP41716.1 - 6.6e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDP41716.1 - 0.00018 20.7 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF1638 PF07796.6 EDP41716.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Seipin PF06775.9 EDP41717.1 - 3.2e-34 118.1 0.0 6.9e-34 117.1 0.0 1.5 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TAP42 PF04177.7 EDP41718.1 - 3e-59 200.6 0.0 3.8e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DAGK_cat PF00781.19 EDP41719.1 - 2.8e-21 75.2 0.0 5.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EDP41719.1 - 0.0011 17.8 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Thioredoxin PF00085.15 EDP41720.1 - 6.8e-56 186.3 0.0 1.3e-27 95.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EDP41720.1 - 1.2e-21 77.1 0.1 1.2e-21 77.1 0.0 3.1 4 0 0 4 4 4 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EDP41720.1 - 2.2e-17 63.2 0.3 9.7e-08 32.1 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDP41720.1 - 9.9e-14 51.2 0.4 1e-05 25.5 0.1 3.7 3 2 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EDP41720.1 - 6.4e-12 45.3 0.2 8.1e-06 25.7 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EDP41720.1 - 2.3e-08 33.7 0.0 0.0037 16.9 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 EDP41720.1 - 1.9e-06 27.8 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.5 EDP41720.1 - 1.8e-05 24.2 0.1 0.027 14.0 0.0 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.1 EDP41720.1 - 0.00025 20.5 0.0 0.54 9.7 0.0 2.6 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EDP41720.1 - 0.00082 19.4 2.1 0.29 11.1 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin DDE_Tnp_1_2 PF13586.1 EDP41720.1 - 0.0076 16.4 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Transposase DDE domain HyaE PF07449.6 EDP41720.1 - 0.025 14.4 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EDP41720.1 - 0.046 13.2 0.1 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF953 PF06110.6 EDP41720.1 - 0.046 13.1 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Mu-like_Com PF10122.4 EDP41720.1 - 0.15 11.1 1.6 12 5.0 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Glutaredoxin PF00462.19 EDP41720.1 - 0.86 9.6 5.1 9.3 6.3 0.6 3.3 2 2 0 2 2 2 0 Glutaredoxin Amidohydro_1 PF01979.15 EDP41721.1 - 8.9e-58 196.5 2.1 1.3e-57 195.9 1.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EDP41721.1 - 3.3e-52 175.7 0.7 6.9e-52 174.6 0.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 EDP41721.1 - 1.9e-35 120.8 0.0 3.7e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 EDP41721.1 - 1.4e-25 89.0 0.0 2.9e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 EDP41721.1 - 1.4e-05 24.8 0.9 3.6e-05 23.4 0.6 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDP41721.1 - 0.00039 19.7 0.1 0.0049 16.1 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family ubiquitin PF00240.18 EDP41722.1 - 3e-21 74.5 0.3 3.6e-21 74.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDP41722.1 - 1.8e-14 53.1 0.4 2.1e-14 52.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDP41722.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain AhpC-TSA PF00578.16 EDP41723.1 - 0.00015 21.4 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family UEV PF05743.8 EDP41724.1 - 1.7e-08 34.1 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 UEV domain TelA PF05816.6 EDP41724.1 - 0.0037 16.0 0.0 0.0047 15.6 0.0 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DEAD PF00270.24 EDP41725.1 - 7.7e-07 28.7 0.1 1.5e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP41725.1 - 3.9e-06 26.6 0.0 8.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DHH PF01368.15 EDP41726.1 - 8.6e-09 35.1 0.0 4.6e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 DHH family Pox_A32 PF04665.7 EDP41726.1 - 0.028 13.7 0.2 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein DHHA2 PF02833.9 EDP41727.1 - 0.0074 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain Iron_traffic PF04362.9 EDP41727.1 - 0.13 11.7 0.3 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking DUF155 PF02582.9 EDP41728.1 - 3.1e-52 176.9 0.0 6.4e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TFIIA PF03153.8 EDP41728.1 - 0.0026 17.7 0.7 0.0026 17.7 0.5 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EDP41728.1 - 0.0028 15.7 3.4 0.0028 15.7 2.4 1.9 2 0 0 2 2 2 1 CDC45-like protein DUF2890 PF11081.3 EDP41728.1 - 0.0051 16.9 1.4 0.015 15.3 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Nop14 PF04147.7 EDP41728.1 - 0.1 10.4 13.2 0.016 13.1 6.2 1.7 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 EDP41728.1 - 0.15 11.5 12.1 0.37 10.3 8.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin Vfa1 PF08432.5 EDP41728.1 - 0.23 11.4 2.9 0.56 10.2 2.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 EDP41728.1 - 1.6 8.2 8.6 0.24 10.8 2.6 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Vps54 PF07928.7 EDP41729.1 - 2.2e-46 157.3 2.8 1.2e-45 154.9 0.1 2.5 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EDP41729.1 - 3.9e-06 25.9 4.9 8.3e-06 24.9 1.4 2.4 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) TrkH PF02386.11 EDP41729.1 - 0.078 11.5 0.2 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein vATP-synt_E PF01991.13 EDP41729.1 - 0.12 11.6 3.4 0.099 11.9 0.5 2.2 3 0 0 3 3 3 0 ATP synthase (E/31 kDa) subunit RCC1 PF00415.13 EDP41730.1 - 6.3e-20 71.1 0.0 0.00044 20.4 0.0 5.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EDP41730.1 - 1.2e-10 41.5 0.3 5.1e-09 36.4 0.1 3.0 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP41730.1 - 1.6e-10 40.8 0.5 1.3e-08 34.7 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) BTB PF00651.26 EDP41730.1 - 2.6e-08 33.8 0.0 0.00032 20.6 0.0 3.3 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EDP41730.1 - 2.2e-05 24.6 0.0 6.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 EDP41730.1 - 2.5e-05 23.7 0.1 2.5e-05 23.7 0.1 5.9 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EDP41730.1 - 4.8e-05 23.2 1.3 0.0064 16.6 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EDP41730.1 - 0.0008 19.1 0.5 0.061 13.1 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat CAF-1_p150 PF11600.3 EDP41730.1 - 1.6 8.0 21.9 0.19 11.0 5.8 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hamartin PF04388.7 EDP41730.1 - 5.7 5.4 18.7 8.8 4.8 12.9 1.2 1 0 0 1 1 1 0 Hamartin protein Mito_fiss_reg PF05308.6 EDP41731.1 - 2.2 7.6 13.0 0.3 10.4 5.1 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator YchF-GTPase_C PF06071.8 EDP41732.1 - 2.2e-33 113.9 0.0 4.2e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDP41732.1 - 2.1e-14 53.4 0.0 7.6e-14 51.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP41732.1 - 3.7e-06 26.2 0.0 6.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 EDP41732.1 - 0.0031 17.2 0.7 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDP41732.1 - 0.02 14.7 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDP41732.1 - 0.03 14.6 3.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain BetaGal_dom3 PF13363.1 EDP41732.1 - 0.08 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_17 PF13207.1 EDP41732.1 - 0.11 13.3 1.0 0.8 10.5 0.7 2.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDP41732.1 - 0.34 11.1 1.6 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 ABC transporter RNase_HII PF01351.13 EDP41733.1 - 1.9e-19 70.1 0.0 1.4e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII Cor1 PF04803.7 EDP41733.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region Cylicin_N PF15241.1 EDP41733.1 - 0.078 12.8 1.1 0.18 11.7 0.8 1.5 1 0 0 1 1 1 0 Cylicin N-terminus RNase_HII PF01351.13 EDP41734.1 - 1.1e-10 41.4 0.2 1.5e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease HII DNA_pol_A_exo1 PF01612.15 EDP41735.1 - 7.9e-34 116.6 0.3 1.1e-33 116.1 0.2 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EDP41735.1 - 2.4e-12 46.9 0.0 5.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EDP41735.1 - 1e-09 37.9 0.3 2e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 HRDC domain Nitroreductase PF00881.19 EDP41735.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Nitroreductase family ChaB PF06150.7 EDP41735.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 ChaB Cellulase PF00150.13 EDP41736.1 - 8.1e-11 41.6 3.4 1.6e-10 40.6 2.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2613 PF11021.3 EDP41736.1 - 0.33 10.6 7.7 10 5.9 3.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Cellulase PF00150.13 EDP41737.1 - 1.1e-13 51.1 5.3 1.7e-13 50.4 3.7 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3701 PF12482.3 EDP41737.1 - 0.071 12.8 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage integrase protein DEAD PF00270.24 EDP41738.1 - 2.1e-42 144.4 0.2 9.2e-42 142.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP41738.1 - 3.7e-28 97.2 0.4 7.5e-28 96.2 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP41738.1 - 0.0047 16.7 0.0 0.02 14.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDP41738.1 - 0.0073 16.0 0.2 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 EDP41738.1 - 0.011 15.0 0.1 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1253 PF06862.7 EDP41738.1 - 0.027 12.8 0.0 0.16 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF3449 PF11931.3 EDP41739.1 - 8.1e-63 211.4 2.0 6.5e-61 205.2 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3449) zf-met PF12874.2 EDP41739.1 - 4.6e-08 32.9 2.7 6.5e-05 22.9 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EDP41739.1 - 4.6e-06 26.0 1.5 1.1e-05 24.8 1.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EDP41739.1 - 7.5e-06 25.9 6.3 0.00053 20.0 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDP41739.1 - 0.011 15.7 2.3 1.1 9.4 0.4 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) MADF_DNA_bdg PF10545.4 EDP41739.1 - 0.074 13.2 2.8 0.1 12.7 0.0 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like OmpH PF03938.9 EDP41739.1 - 5 7.0 11.3 47 3.8 0.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2175 PF09943.4 EDP41739.1 - 6.8 6.8 6.9 23 5.0 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Ribonuclease_T2 PF00445.13 EDP41742.1 - 6.8e-34 117.1 1.6 1e-33 116.5 0.6 1.6 1 1 1 2 2 2 1 Ribonuclease T2 family TPR_7 PF13176.1 EDP41742.1 - 0.029 14.1 0.1 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat rve PF00665.21 EDP41743.1 - 8.5e-21 74.2 0.0 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EDP41743.1 - 0.0052 16.2 0.3 0.057 12.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain 3-HAO PF06052.7 EDP41743.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase RNA_pol_Rpb1_5 PF04998.12 EDP41744.1 - 9.2e-83 277.6 0.0 2.7e-82 276.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDP41744.1 - 6.9e-60 201.7 0.0 1.7e-59 200.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDP41744.1 - 1.2e-35 122.5 0.0 2.5e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDP41744.1 - 1.7e-20 72.7 0.0 5.8e-20 71.0 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EDP41744.1 - 1.7e-13 50.5 4.7 2.7e-09 36.7 0.4 3.5 2 1 1 3 3 3 3 RNA polymerase Rpb1, domain 1 ThiF PF00899.16 EDP41745.1 - 1.1e-34 119.1 0.0 2.1e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family DAO PF01266.19 EDP41745.1 - 0.0015 17.4 0.1 0.0027 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDP41745.1 - 0.018 14.0 0.3 0.038 13.0 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain XdhC_C PF13478.1 EDP41745.1 - 0.026 14.8 0.0 0.52 10.6 0.0 2.6 2 1 1 3 3 3 0 XdhC Rossmann domain Saccharop_dh PF03435.13 EDP41745.1 - 0.034 13.1 0.1 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EDP41745.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EDP41745.1 - 0.16 11.7 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDP41745.1 - 0.16 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EDP41745.1 - 0.21 11.0 0.1 0.47 9.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 6PF2K PF01591.13 EDP41746.1 - 4.9e-68 228.5 0.0 6.6e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDP41746.1 - 2.6e-30 105.5 0.0 6.5e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDP41746.1 - 2.3e-09 37.2 0.2 5.3e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP41746.1 - 0.00059 20.6 0.0 0.0033 18.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 EDP41746.1 - 0.017 14.3 0.0 0.039 13.1 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 GBP PF02263.14 EDP41746.1 - 0.05 12.6 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Peptidase_M24 PF00557.19 EDP41747.1 - 1.3e-43 148.9 0.0 1.9e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Vesiculo_matrix PF06326.7 EDP41747.1 - 0.036 13.5 1.6 0.059 12.8 1.1 1.3 1 0 0 1 1 1 0 Vesiculovirus matrix protein CDC45 PF02724.9 EDP41747.1 - 2.9 5.8 6.4 3.8 5.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 EDP41748.1 - 8.2e-31 106.3 0.0 8.6e-31 106.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rhodanese PF00581.15 EDP41749.1 - 3.5e-21 75.6 0.0 8.1e-12 45.4 0.0 2.5 2 1 0 2 2 2 2 Rhodanese-like domain Arrestin_N PF00339.24 EDP41750.1 - 1.7e-14 53.9 0.2 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EDP41750.1 - 1.5e-13 50.9 0.9 2.1e-12 47.2 0.3 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Mito_fiss_reg PF05308.6 EDP41750.1 - 0.00013 21.4 2.0 0.00024 20.5 1.4 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator LDB19 PF13002.2 EDP41750.1 - 0.00017 21.1 0.2 0.0022 17.5 0.0 2.5 3 0 0 3 3 3 1 Arrestin_N terminal like Nup188 PF10487.4 EDP41751.1 - 3.2e-11 41.9 0.0 5.5e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Rogdi_lz PF10259.4 EDP41751.1 - 0.023 13.8 0.0 0.067 12.2 0.0 1.7 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Ric8 PF10165.4 EDP41751.1 - 0.32 9.7 1.1 0.48 9.1 0.2 1.7 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn COG6 PF06419.6 EDP41752.1 - 2.9e-46 157.8 0.0 3.8e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 B12-binding PF02310.14 EDP41752.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Macro PF01661.16 EDP41753.1 - 3.6e-38 130.0 0.1 4.9e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Macro domain Methyltransf_23 PF13489.1 EDP41754.1 - 1.2e-09 38.0 0.1 1.7e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41754.1 - 1.4e-08 35.0 0.0 2.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41754.1 - 6.5e-06 26.7 0.0 1.2e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP41754.1 - 7.5e-06 26.2 0.0 4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDP41754.1 - 1.6e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EDP41754.1 - 0.00014 21.8 0.0 0.00023 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP41754.1 - 0.00019 21.0 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP41754.1 - 0.0036 17.7 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EDP41754.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Nucleoporin_N PF08801.6 EDP41755.1 - 3.2e-12 45.9 0.0 3.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EDP41756.1 - 8.1e-54 183.1 4.0 1.2e-53 182.5 2.8 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1682 PF07946.9 EDP41757.1 - 1.5e-48 165.2 0.0 1.9e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) USP7_ICP0_bdg PF12436.3 EDP41758.1 - 2.2e-80 269.4 0.9 4.2e-80 268.5 0.6 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EDP41758.1 - 1.3e-66 224.0 1.3 2.6e-63 213.3 0.3 2.6 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EDP41758.1 - 1.3e-56 191.7 0.1 1.9e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP41758.1 - 1.5e-33 116.5 0.0 2.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EDP41758.1 - 6.3e-10 39.3 0.1 1.1e-07 32.1 0.0 3.8 2 2 1 3 3 3 1 MATH domain Chalcone PF02431.10 EDP41759.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Abhydrolase_6 PF12697.2 EDP41760.1 - 2.5e-18 66.8 0.0 3.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP41760.1 - 4.5e-14 52.5 0.0 1.5e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP41760.1 - 9.4e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDP41760.1 - 3.2e-07 30.1 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase PF07224.6 EDP41760.1 - 0.023 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.15 EDP41760.1 - 0.039 14.1 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EDP41760.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EDP41760.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Arrestin_N PF00339.24 EDP41761.1 - 4.5e-05 23.3 0.2 0.0096 15.7 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Polysacc_deac_1 PF01522.16 EDP41762.1 - 4.2e-30 103.9 0.0 9.2e-30 102.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TauD PF02668.11 EDP41763.1 - 1.2e-38 133.2 0.1 1.6e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribonuclease PF00545.15 EDP41764.1 - 6.3e-10 38.9 0.0 7.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ribonuclease PI3_PI4_kinase PF00454.22 EDP41765.1 - 1.4e-34 119.6 0.0 1.6e-33 116.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDP41765.1 - 1.1e-22 80.0 0.0 2.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 EDP41765.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) cwf18 PF08315.7 EDP41766.1 - 5.5e-25 88.2 2.5 6.7e-25 88.0 1.7 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF2594 PF10769.4 EDP41766.1 - 0.098 12.7 0.4 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) NifQ PF04891.7 EDP41766.1 - 1 9.4 3.4 1 9.4 0.7 1.8 1 1 1 2 2 2 0 NifQ zf-Mss51 PF13824.1 EDP41767.1 - 2.2e-21 75.4 1.1 3.9e-21 74.6 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 cobW PF02492.14 EDP41768.1 - 1e-34 119.5 0.0 1.3e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EDP41768.1 - 4e-07 29.0 1.1 1.9e-06 26.8 0.8 1.8 1 1 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 EDP41768.1 - 0.0019 18.4 0.0 0.0036 17.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EDP41768.1 - 0.0023 18.7 0.0 0.0033 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDP41768.1 - 0.01 15.7 0.0 0.032 14.2 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 EDP41768.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Arch_ATPase PF01637.13 EDP41768.1 - 0.035 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EDP41768.1 - 0.071 12.8 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 NTPase ABC_tran PF00005.22 EDP41768.1 - 0.075 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EDP41768.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDP41768.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EDP41768.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein CoaE PF01121.15 EDP41768.1 - 0.13 11.6 0.1 0.68 9.3 0.0 2.0 1 1 0 2 2 2 0 Dephospho-CoA kinase Vma12 PF11712.3 EDP41769.1 - 5.3e-15 55.3 0.0 7.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase AFG1_ATPase PF03969.11 EDP41770.1 - 1.2e-86 290.7 0.9 4.8e-83 278.9 0.0 2.9 2 1 0 3 3 3 2 AFG1-like ATPase AAA_22 PF13401.1 EDP41770.1 - 1e-06 28.9 0.0 4.3e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP41770.1 - 0.0094 15.9 0.8 0.13 12.2 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EDP41770.1 - 0.045 13.9 0.8 0.27 11.4 0.0 2.7 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP41770.1 - 0.047 13.4 0.1 0.31 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDP41770.1 - 0.094 12.9 0.1 0.84 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mad3_BUB1_I PF08311.7 EDP41771.1 - 7.2e-37 125.9 0.3 1.2e-36 125.2 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EDP41771.1 - 7.3e-15 54.8 0.0 1.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP41771.1 - 0.026 13.5 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Telomere_Sde2 PF13019.1 EDP41771.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Telomere stability and silencing TFIIA PF03153.8 EDP41771.1 - 0.53 10.1 12.7 0.015 15.2 3.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Brix PF04427.13 EDP41772.1 - 1.2e-54 184.9 0.0 1.5e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Cpn60_TCP1 PF00118.19 EDP41773.1 - 7.5e-141 470.0 8.3 8.5e-141 469.8 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EDP41773.1 - 0.00039 19.7 0.1 0.0018 17.5 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination Pkinase PF00069.20 EDP41774.1 - 1.4e-61 207.9 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP41774.1 - 4.4e-25 88.2 0.0 5.5e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP41774.1 - 8.2e-07 28.2 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP41774.1 - 2.9e-05 23.2 0.1 4.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDP41774.1 - 0.00032 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EDP41774.1 - 0.029 14.0 0.1 0.053 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2423 PF10338.4 EDP41775.1 - 6.7e-13 48.3 1.9 6.7e-13 48.3 1.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) TMEM51 PF15345.1 EDP41775.1 - 7 6.2 9.1 8.8 5.9 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Ank_2 PF12796.2 EDP41776.1 - 4.8e-42 142.2 8.6 1.6e-16 60.4 0.6 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDP41776.1 - 7.4e-31 104.4 9.2 8.7e-07 28.4 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EDP41776.1 - 2.2e-25 88.5 3.1 1.9e-08 34.5 0.1 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP41776.1 - 2.3e-21 75.3 6.6 4.7e-05 23.4 0.1 6.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP41776.1 - 4.8e-20 69.6 7.9 0.0047 17.0 0.1 7.8 7 0 0 7 7 7 6 Ankyrin repeat GDPD PF03009.12 EDP41776.1 - 9.1e-12 45.0 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ProQ PF04352.8 EDP41776.1 - 0.12 11.9 0.5 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 ProQ/FINO family SPX PF03105.14 EDP41777.1 - 2.9e-07 30.5 0.0 3.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 SPX domain CRM1_C PF08767.6 EDP41778.1 - 3.6e-127 423.6 2.9 1.5e-126 421.6 0.0 3.3 3 1 1 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 EDP41778.1 - 1.2e-40 138.7 4.1 2.4e-39 134.5 0.5 4.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EDP41778.1 - 1.7e-13 50.2 0.7 1e-12 47.7 0.5 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.8 EDP41778.1 - 0.0064 16.4 0.1 2.3 8.1 0.0 4.3 4 0 0 4 4 4 1 UME (NUC010) domain Zn_peptidase PF04228.8 EDP41778.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase zf-C2H2 PF00096.21 EDP41780.1 - 1.8e-06 27.9 9.9 0.00095 19.3 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP41780.1 - 0.00023 21.2 8.0 0.039 14.2 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDP41780.1 - 0.028 14.6 6.4 0.071 13.4 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDP41780.1 - 0.042 13.7 2.7 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDP41780.1 - 2 8.1 8.0 0.33 10.6 1.8 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type bZIP_1 PF00170.16 EDP41781.1 - 6.2e-08 32.4 12.3 1.5e-07 31.2 8.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDP41781.1 - 0.0001 22.0 9.1 0.00024 20.8 6.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF4047 PF13256.1 EDP41781.1 - 0.0053 16.7 0.9 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) bZIP_Maf PF03131.12 EDP41781.1 - 0.065 13.5 6.7 0.15 12.3 4.6 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 EDP41781.1 - 0.079 12.7 1.6 0.15 11.8 1.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Glutaredoxin PF00462.19 EDP41782.1 - 1.4e-17 63.4 0.0 2.2e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin PDCD2_C PF04194.8 EDP41783.1 - 3.8e-33 114.4 0.0 3.8e-33 114.4 0.0 2.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CDC45 PF02724.9 EDP41783.1 - 4 5.3 8.7 6.5 4.6 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EDP41783.1 - 4.1 7.7 7.1 8.7 6.7 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EDP41783.1 - 4.4 5.0 11.9 6.5 4.5 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family MTHFR PF02219.12 EDP41784.1 - 4.7e-97 324.5 0.0 3e-96 321.9 0.0 1.9 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase AAA PF00004.24 EDP41785.1 - 1.2e-11 44.9 0.0 2.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP41785.1 - 1.9e-09 37.8 0.1 1.6e-07 31.5 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDP41785.1 - 7.8e-07 29.3 0.0 2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 EDP41785.1 - 0.00036 20.1 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 CDC6, C terminal AAA_11 PF13086.1 EDP41785.1 - 0.041 13.4 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDP41785.1 - 0.046 13.4 2.3 0.054 13.2 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain ORC5_C PF14630.1 EDP41785.1 - 0.093 12.1 1.7 7.6 5.8 0.0 3.2 4 1 0 4 4 4 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF815 PF05673.8 EDP41785.1 - 0.2 10.5 0.0 0.7 8.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SOG2 PF10428.4 EDP41785.1 - 4.2 5.9 11.5 6.1 5.3 8.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_22 PF03901.12 EDP41786.1 - 3e-66 224.1 25.3 3.7e-66 223.8 17.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Exo_endo_phos PF03372.18 EDP41787.1 - 6.2e-19 68.8 0.0 9.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3392 PF11872.3 EDP41787.1 - 0.024 14.5 2.2 0.78 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Ank PF00023.25 EDP41789.1 - 1.2e-15 56.3 3.8 4.4e-07 29.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDP41789.1 - 8.3e-14 51.6 3.4 5.8e-08 33.0 0.8 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDP41789.1 - 3.9e-13 49.5 0.6 1.4e-12 47.8 0.4 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EDP41789.1 - 8.8e-13 48.0 0.6 6.1e-12 45.3 0.3 2.6 3 0 0 3 3 3 1 IPT/TIG domain Ank_5 PF13857.1 EDP41789.1 - 5.6e-09 35.9 7.2 2.7e-06 27.4 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP41789.1 - 8.7e-08 31.6 3.3 0.00022 21.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat DPBB_1 PF03330.13 EDP41790.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cu_bind_like PF02298.12 EDP41790.1 - 0.0089 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Plastocyanin-like domain TMEM95 PF15203.1 EDP41790.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 1 0 2 2 2 0 TMEM95 family RHD3 PF05879.7 EDP41791.1 - 3.2e-234 779.2 0.0 6.3e-234 778.2 0.0 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EDP41791.1 - 1.3e-05 24.3 0.1 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EDP41791.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDP41791.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EDP41791.1 - 0.00056 19.9 0.0 0.0022 17.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EDP41791.1 - 0.00088 19.7 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein NTF2 PF02136.15 EDP41792.1 - 2.7e-28 98.7 0.4 2.7e-28 98.7 0.3 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EDP41792.1 - 2.6e-09 36.5 0.0 5.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP41792.1 - 2.1e-08 34.0 0.1 5.7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP41792.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 EDP41792.1 - 0.0012 18.3 28.4 0.002 17.6 19.7 1.3 1 0 0 1 1 1 1 Vta1 like Limkain-b1 PF11608.3 EDP41792.1 - 0.012 15.2 0.1 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 SOBP PF15279.1 EDP41792.1 - 1.9 8.8 17.0 3.3 8.0 11.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.8 EDP41792.1 - 3.4 6.9 13.5 6 6.1 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dynamin_M PF01031.15 EDP41793.1 - 3.8e-104 347.6 0.0 5.6e-104 347.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDP41793.1 - 3.6e-33 114.7 0.0 7.6e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EDP41793.1 - 7.9e-28 96.1 2.0 1.7e-27 95.1 1.4 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain TatD_DNase PF01026.16 EDP41794.1 - 5.3e-32 111.0 0.0 6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EDP41794.1 - 0.011 15.3 0.2 0.094 12.2 0.0 2.4 2 2 1 3 3 3 0 Amidohydrolase Cyclin_N PF00134.18 EDP41795.1 - 2.2e-44 150.0 0.8 5e-44 148.9 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDP41795.1 - 1.1e-25 89.8 0.3 5.1e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-HIT PF04438.11 EDP41796.1 - 1.2e-05 24.8 8.6 1.7e-05 24.3 6.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Pox_A9 PF04835.7 EDP41798.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 A9 protein conserved region Prenyltrans PF00432.16 EDP41799.1 - 1.4e-20 72.4 18.2 8.7e-07 28.3 0.0 6.1 4 2 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDP41799.1 - 1.3e-12 48.0 0.5 1.6e-06 28.4 0.1 4.3 3 1 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDP41799.1 - 0.002 18.1 0.0 0.089 12.8 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Thioredoxin PF00085.15 EDP41800.1 - 5.1e-27 93.5 0.0 2e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EDP41800.1 - 5.9e-06 26.4 0.1 5.9e-06 26.4 0.1 3.0 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDP41800.1 - 7.5e-05 22.6 0.2 0.00045 20.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EDP41800.1 - 7.9e-05 22.6 0.0 0.00072 19.6 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EDP41800.1 - 0.00016 21.5 0.0 0.00048 19.9 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EDP41800.1 - 0.022 14.4 0.1 0.079 12.6 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EDP41800.1 - 0.023 14.2 2.2 0.023 14.2 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EDP41800.1 - 0.73 9.8 11.4 4.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin PPR_2 PF13041.1 EDP41801.1 - 0.011 15.6 0.0 1.2 9.1 0.0 3.5 4 0 0 4 4 4 0 PPR repeat family DUF3405 PF11885.3 EDP41802.1 - 3e-128 428.2 10.8 1e-125 419.8 7.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) DUF3609 PF12259.3 EDP41803.1 - 0.033 12.8 0.0 0.059 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) CPSF73-100_C PF11718.3 EDP41803.1 - 0.51 9.6 2.0 1.1 8.5 1.4 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 EDP41804.1 - 1.3e-16 60.7 0.1 2.4e-16 59.8 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain STT3 PF02516.9 EDP41805.1 - 9.8e-126 420.5 40.6 2.1e-125 419.4 28.1 1.5 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit AAA PF00004.24 EDP41806.1 - 9.2e-60 200.6 0.0 1.6e-45 154.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP41806.1 - 2.1e-07 30.7 0.0 0.0048 16.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDP41806.1 - 4.6e-07 29.1 0.0 0.0034 16.4 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDP41806.1 - 1.7e-06 28.8 0.0 0.013 16.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP41806.1 - 2e-06 27.9 8.4 0.013 15.4 0.1 4.6 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EDP41806.1 - 8.1e-06 26.0 0.3 0.0063 16.6 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDP41806.1 - 1.2e-05 25.2 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EDP41806.1 - 5.5e-05 22.8 0.1 0.0023 17.6 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EDP41806.1 - 0.00026 20.0 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.1 EDP41806.1 - 0.00032 20.1 0.3 0.017 14.5 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDP41806.1 - 0.00075 19.1 0.6 0.4 10.2 0.0 3.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EDP41806.1 - 0.0011 18.4 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EDP41806.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EDP41806.1 - 0.0013 18.4 0.5 1.6 8.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 EDP41806.1 - 0.0016 17.9 0.0 0.73 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EDP41806.1 - 0.0037 17.2 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP41806.1 - 0.0044 16.9 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EDP41806.1 - 0.0074 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.12 EDP41806.1 - 0.0088 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 EDP41806.1 - 0.01 14.9 0.5 0.039 13.1 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDP41806.1 - 0.011 15.8 0.0 0.073 13.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EDP41806.1 - 0.012 15.2 0.3 0.028 14.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EDP41806.1 - 0.013 15.5 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ArgK PF03308.11 EDP41806.1 - 0.015 14.0 0.2 0.015 14.0 0.1 1.6 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EDP41806.1 - 0.018 15.3 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EDP41806.1 - 0.028 13.1 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 EDP41806.1 - 0.029 14.0 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 EDP41806.1 - 0.029 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EDP41806.1 - 0.077 12.6 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 EDP41806.1 - 0.17 10.8 0.0 7.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 EDP41806.1 - 0.31 9.8 0.0 1.7 7.4 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain FAM75 PF14650.1 EDP41806.1 - 0.36 10.1 16.5 0.64 9.3 11.5 1.4 1 0 0 1 1 1 0 FAM75 family Ldh_1_C PF02866.13 EDP41807.1 - 4.6e-46 156.7 0.9 4.8e-46 156.6 0.1 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EDP41807.1 - 8.5e-44 148.8 0.0 1.7e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDP41807.1 - 1.1e-05 24.3 0.0 1.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDP41807.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2279 PF10043.4 EDP41807.1 - 0.074 13.3 0.7 0.44 10.8 0.7 2.1 2 1 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) Semialdhyde_dh PF01118.19 EDP41807.1 - 0.088 13.1 0.2 0.83 9.9 0.0 2.6 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DUF3144 PF11342.3 EDP41807.1 - 0.11 12.5 0.4 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) COG7 PF10191.4 EDP41808.1 - 7.5e-28 96.9 14.0 4.6e-18 64.5 7.5 3.2 2 1 0 3 3 3 3 Golgi complex component 7 (COG7) DAHP_synth_1 PF00793.15 EDP41809.1 - 6.4e-91 303.8 0.0 7.5e-91 303.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family HEAT PF02985.17 EDP41811.1 - 1.5e-20 71.3 4.4 0.0013 18.6 0.0 10.0 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 EDP41811.1 - 1.2e-12 47.8 16.9 2.6e-05 24.5 0.0 8.2 8 0 0 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EDP41811.1 - 5.3e-12 45.8 9.9 0.00038 20.6 0.0 6.5 2 2 6 8 8 8 5 HEAT repeats IBN_N PF03810.14 EDP41811.1 - 2.4e-09 36.9 2.9 1.5e-07 31.1 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 EDP41811.1 - 0.0014 18.4 4.4 1.6 8.6 0.1 4.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EDP41811.1 - 0.017 14.3 1.4 4.3 6.5 0.0 2.9 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 EDP41811.1 - 0.02 13.1 1.6 0.058 11.6 0.0 2.4 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.7 EDP41811.1 - 0.23 11.1 5.2 1.1 8.8 0.0 4.0 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis SNF2_N PF00176.18 EDP41812.1 - 1.1e-79 267.3 0.1 2e-79 266.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EDP41812.1 - 1.5e-40 137.6 0.4 5.3e-40 135.8 0.3 2.1 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EDP41812.1 - 3.4e-26 91.8 1.8 3.4e-26 91.8 1.2 3.6 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EDP41812.1 - 1.8e-13 50.1 0.0 7.8e-13 48.0 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDP41812.1 - 1.2e-10 40.7 0.0 3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EDP41812.1 - 1.1e-06 28.5 2.2 1.3e-05 25.1 0.0 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDP41812.1 - 1.2e-06 28.1 0.0 3.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 EDP41812.1 - 8e-05 22.7 1.4 8e-05 22.7 0.9 4.1 3 0 0 3 3 3 1 DNA-binding domain AAA_14 PF13173.1 EDP41812.1 - 0.024 14.5 0.0 0.1 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.10 EDP41812.1 - 0.048 13.0 0.1 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 DUF2407_C PF13373.1 EDP41814.1 - 2.1e-11 43.9 2.3 2.1e-11 43.9 1.6 2.7 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EDP41814.1 - 0.00019 21.5 0.0 0.031 14.4 0.0 3.0 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain PBP1_TM PF14812.1 EDP41814.1 - 0.16 12.2 2.5 4.6 7.6 1.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S8 PF00082.17 EDP41815.1 - 2.2e-55 187.8 1.6 3.3e-55 187.2 1.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EDP41815.1 - 8e-26 89.6 0.7 1.5e-25 88.7 0.1 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain TFIIA PF03153.8 EDP41815.1 - 0.0075 16.2 0.7 0.0075 16.2 0.5 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Calreticulin PF00262.13 EDP41816.1 - 2.7e-157 523.1 7.1 3.5e-157 522.7 4.9 1.1 1 0 0 1 1 1 1 Calreticulin family Lyase_1 PF00206.15 EDP41817.1 - 2.6e-96 322.4 0.0 3.8e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EDP41817.1 - 9.7e-30 102.4 0.0 2e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DnaJ PF00226.26 EDP41818.1 - 1.6e-23 82.2 0.5 2.4e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDP41818.1 - 6.7e-18 64.3 0.0 6.8e-17 61.1 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDP41818.1 - 5.2e-12 45.6 23.1 8.6e-12 44.9 16.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 EDP41818.1 - 0.00053 20.2 8.5 0.001 19.3 5.9 1.5 1 0 0 1 1 1 1 Cytochrome c3 HypA PF01155.14 EDP41818.1 - 0.43 10.2 9.2 1.9 8.1 1.9 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 EDP41818.1 - 8.9 6.4 11.5 4.2 7.4 2.9 2.4 1 1 1 2 2 2 0 Stc1 domain Glyco_hydro_85 PF03644.8 EDP41820.1 - 1.3e-69 234.7 0.1 2e-69 234.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SNARE PF05739.14 EDP41821.1 - 1.6e-17 62.8 4.8 5.5e-17 61.2 1.7 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EDP41821.1 - 6.4e-17 61.4 6.9 1.2e-16 60.5 0.0 2.8 2 1 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 EDP41821.1 - 0.0023 17.5 8.1 0.0027 17.2 2.5 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.6 EDP41821.1 - 0.041 13.7 12.9 0.22 11.3 8.5 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.16 EDP41821.1 - 0.073 12.6 0.3 0.073 12.6 0.2 2.3 2 0 0 2 2 2 0 Synaptobrevin FlaC_arch PF05377.6 EDP41821.1 - 0.11 12.3 2.5 17 5.4 0.3 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FDF PF09532.5 EDP41821.1 - 0.15 12.6 2.4 0.37 11.3 1.7 1.8 1 0 0 1 1 1 0 FDF domain TMPIT PF07851.8 EDP41821.1 - 0.59 9.1 5.2 0.11 11.5 1.1 1.6 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin PF00804.20 EDP41821.1 - 5.8 7.1 13.3 3.4e+02 1.4 9.2 3.0 1 1 0 1 1 1 0 Syntaxin DUF1664 PF07889.7 EDP41821.1 - 6.6 6.5 8.4 3.5 7.4 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EDP41821.1 - 7.3 6.5 9.0 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TAF PF02969.12 EDP41822.1 - 1.6e-29 101.6 0.4 2.6e-29 100.9 0.3 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EDP41822.1 - 6.2e-06 26.2 0.3 1.1e-05 25.3 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF421 PF04239.7 EDP41822.1 - 0.099 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF421) THF_DHG_CYH PF00763.18 EDP41823.1 - 7.8e-18 64.6 0.0 5.4e-08 32.8 0.0 2.4 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EDP41823.1 - 1.3e-13 50.3 0.0 7.1e-09 34.9 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 EDP41823.1 - 0.0006 18.7 0.1 0.00085 18.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Shikimate_DH PF01488.15 EDP41823.1 - 0.069 13.2 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AMOP PF03782.12 EDP41823.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 AMOP domain RRM_1 PF00076.17 EDP41824.1 - 6.7e-12 44.8 0.2 2.9e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP41824.1 - 4.8e-11 42.4 0.0 8.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP41824.1 - 0.004 16.9 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.15 EDP41826.1 - 1.3e-19 70.1 0.0 1.3e-19 70.1 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDP41826.1 - 7.9e-14 52.5 0.0 1.8e-12 48.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP41826.1 - 2.3e-12 47.4 0.1 4.4e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP41826.1 - 3e-07 30.3 0.0 8.7e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDP41826.1 - 0.00011 21.9 0.1 0.00031 20.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Vps35 PF03635.12 EDP41827.1 - 3.3e-295 981.1 0.0 3.8e-295 980.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribosomal_L18ae PF01775.12 EDP41828.1 - 5.3e-57 191.0 1.7 6.4e-57 190.8 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RRM_6 PF14259.1 EDP41829.1 - 2.3e-15 56.3 0.1 1.5e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP41829.1 - 4.5e-12 45.6 0.2 4.4e-09 36.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP41829.1 - 1.4e-08 34.3 0.0 0.00042 20.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EDP41829.1 - 3.6e-08 32.9 0.0 0.0039 16.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EDP41829.1 - 1.4e-06 27.7 3.4 2.7e-06 26.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 EDP41829.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 PWI domain RRM_3 PF08777.6 EDP41829.1 - 0.018 14.8 0.1 2 8.2 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif SAP PF02037.22 EDP41829.1 - 0.02 14.3 0.1 0.047 13.2 0.1 1.7 1 0 0 1 1 1 0 SAP domain ubiquitin PF00240.18 EDP41830.1 - 1e-34 117.6 0.7 1.6e-34 117.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EDP41830.1 - 2.1e-30 104.0 11.3 4e-30 103.1 7.8 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EDP41830.1 - 1.7e-19 69.2 0.7 1.7e-19 69.2 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDP41830.1 - 1.1e-05 25.5 0.1 5.1e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDP41830.1 - 0.00017 21.3 0.0 0.0005 19.8 0.0 1.7 1 1 1 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDP41830.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDP41830.1 - 0.01 15.9 0.3 0.027 14.6 0.2 1.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 EDP41830.1 - 0.22 11.3 1.7 0.53 10.1 0.2 2.0 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-C2H2_2 PF12756.2 EDP41831.1 - 3.9e-23 81.4 0.0 7.2e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CDC45 PF02724.9 EDP41831.1 - 0.022 12.8 2.5 0.021 12.9 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NST1 PF13945.1 EDP41833.1 - 3.5e-24 85.9 16.2 5.6e-24 85.2 0.1 2.9 3 0 0 3 3 3 2 Salt tolerance down-regulator YL1 PF05764.8 EDP41833.1 - 0.0035 16.9 1.7 0.0035 16.9 1.2 2.8 3 0 0 3 3 3 2 YL1 nuclear protein MIP-T3 PF10243.4 EDP41834.1 - 1.9e-05 23.3 47.5 2.4e-05 23.0 32.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 HC2 PF07382.6 EDP41834.1 - 0.00057 19.8 29.6 0.00057 19.8 20.5 2.1 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Evr1_Alr PF04777.8 EDP41835.1 - 8.8e-25 86.4 0.3 2.4e-24 85.0 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family UCH PF00443.24 EDP41836.1 - 9.8e-69 231.4 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP41836.1 - 6.1e-26 91.5 0.0 8.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EDP41836.1 - 9.5e-05 22.7 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 EDP41836.1 - 0.0057 16.1 0.3 0.014 14.8 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger CRC_subunit PF08624.5 EDP41837.1 - 1e-43 148.5 0.0 3.8e-43 146.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit PPR_2 PF13041.1 EDP41838.1 - 1.3e-06 28.2 0.0 0.00012 21.9 0.0 3.5 3 1 1 4 4 4 1 PPR repeat family PPR_3 PF13812.1 EDP41838.1 - 0.0032 17.6 5.4 0.0079 16.4 0.1 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EDP41838.1 - 0.043 13.8 0.2 0.36 10.9 0.0 2.7 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.1 EDP41838.1 - 0.19 12.4 6.5 5.2 7.9 0.0 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat eIF2_C PF09173.6 EDP41839.1 - 1e-37 128.0 0.1 2.3e-37 126.8 0.1 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 EDP41839.1 - 4.8e-37 127.2 0.0 8.1e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EDP41839.1 - 3.7e-11 42.9 0.5 3.7e-11 42.9 0.4 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP41839.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDP41839.1 - 0.053 13.3 0.2 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Dynamin family Got1 PF04178.7 EDP41840.1 - 5.1e-15 55.6 12.2 9.6e-08 32.1 1.5 2.2 1 1 1 2 2 2 2 Got1/Sft2-like family DUF2632 PF10943.3 EDP41840.1 - 0.037 13.5 2.6 0.045 13.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) DUF4396 PF14342.1 EDP41840.1 - 0.33 11.0 5.2 0.67 10.0 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) ABC2_membrane_4 PF12730.2 EDP41840.1 - 1.5 7.9 13.9 2 7.5 9.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YrhK PF14145.1 EDP41840.1 - 4.8 6.9 10.7 0.16 11.6 1.8 2.5 3 0 0 3 3 3 0 YrhK-like protein ATP_sub_h PF10775.4 EDP41841.1 - 7.4e-21 73.6 2.4 9.3e-21 73.3 0.8 1.8 2 0 0 2 2 2 1 ATP synthase complex subunit h DUF3519 PF12033.3 EDP41841.1 - 0.062 13.4 0.2 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3519) IATP PF04568.7 EDP41842.1 - 3.8e-14 52.5 0.9 4.6e-14 52.2 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP AAA_11 PF13086.1 EDP41843.1 - 3.8e-50 170.6 0.7 5.8e-50 170.0 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EDP41843.1 - 1.1e-45 155.5 0.0 3.2e-45 153.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDP41843.1 - 1.4e-13 50.3 4.0 3.4e-12 45.9 0.6 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDP41843.1 - 2e-13 50.3 0.1 1.9e-08 34.1 0.0 3.4 2 1 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 EDP41843.1 - 0.00038 19.8 0.1 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EDP41843.1 - 0.012 15.5 0.4 0.079 12.9 0.2 2.5 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EDP41843.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EDP41843.1 - 0.14 11.0 0.1 0.29 10.0 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) OTU PF02338.14 EDP41844.1 - 7.6e-11 42.6 0.7 4.1e-10 40.2 0.1 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDP41844.1 - 0.00096 18.5 0.3 0.84 8.9 0.4 2.2 1 1 0 2 2 2 2 Peptidase C65 Otubain Apc1 PF12859.2 EDP41845.1 - 2e-17 63.3 0.0 5.1e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EDP41845.1 - 0.014 15.5 13.9 0.026 14.7 0.1 5.3 5 0 0 5 5 5 0 Proteasome/cyclosome repeat RrnaAD PF00398.15 EDP41846.1 - 9.3e-57 192.0 0.0 2.4e-56 190.6 0.0 1.5 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EDP41846.1 - 1.6e-10 41.0 0.0 3.2e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41846.1 - 6.4e-07 29.9 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDP41846.1 - 9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EDP41846.1 - 9.8e-06 25.9 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41846.1 - 2.5e-05 24.6 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDP41846.1 - 7.9e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EDP41846.1 - 9.8e-05 21.9 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP41846.1 - 0.00039 20.1 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDP41846.1 - 0.00056 19.0 0.0 0.00088 18.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EDP41846.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.13 EDP41846.1 - 0.0056 15.9 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EDP41846.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EDP41846.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 EDP41846.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_28 PF02636.12 EDP41846.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Adaptin_N PF01602.15 EDP41847.1 - 3.3e-139 464.5 5.4 4.1e-139 464.2 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDP41847.1 - 1.7e-27 96.4 1.2 1.8e-22 80.0 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDP41847.1 - 7.4e-19 67.8 6.7 2.1e-07 31.1 0.0 6.4 2 1 5 7 7 7 6 HEAT repeats HEAT PF02985.17 EDP41847.1 - 7.4e-14 50.5 4.2 0.0041 17.0 0.0 7.6 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EDP41847.1 - 1.6e-06 28.4 5.1 0.51 10.9 0.0 7.4 8 1 1 9 9 9 1 HEAT-like repeat Cnd3 PF12719.2 EDP41847.1 - 0.00012 21.2 0.3 0.0005 19.1 0.1 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EDP41847.1 - 0.0027 17.0 0.4 0.29 10.4 0.0 3.3 3 1 1 4 4 4 1 CLASP N terminal Cohesin_HEAT PF12765.2 EDP41847.1 - 0.02 14.8 0.1 2.1 8.4 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sec7_N PF12783.2 EDP41847.1 - 0.072 12.5 0.2 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_PBS PF03130.11 EDP41847.1 - 0.91 10.1 7.3 91 3.9 0.1 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF3074 PF11274.3 EDP41848.1 - 2e-39 135.1 0.0 3.6e-39 134.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) Kelch_5 PF13854.1 EDP41849.1 - 2.2e-14 53.0 1.6 4.6e-07 29.6 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 EDP41849.1 - 1.5e-12 47.2 4.8 0.0014 18.7 0.4 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EDP41849.1 - 9.8e-11 41.2 7.6 0.00014 21.5 0.0 6.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDP41849.1 - 3.5e-06 26.9 4.1 0.0023 18.0 0.2 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EDP41849.1 - 0.00049 19.7 0.2 0.0038 16.9 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 EDP41849.1 - 0.012 15.1 2.5 0.057 12.9 0.2 3.2 3 0 0 3 3 3 0 Kelch motif Bacteriocin_IIc PF10439.4 EDP41849.1 - 0.036 14.1 4.4 0.46 10.6 1.7 2.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Aldose_epim PF01263.15 EDP41850.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Aldose 1-epimerase ZU5 PF00791.15 EDP41850.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ZU5 domain PMT PF02366.13 EDP41851.1 - 8.5e-78 261.0 15.9 8.5e-78 261.0 11.0 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDP41851.1 - 8.2e-16 58.0 1.9 1.1e-14 54.4 0.7 2.2 1 1 1 2 2 2 2 MIR domain Stonin2_N PF12016.3 EDP41852.1 - 0.078 12.1 0.7 0.096 11.8 0.5 1.0 1 0 0 1 1 1 0 Stonin 2 GMC_oxred_N PF00732.14 EDP41853.1 - 8.6e-37 126.8 0.2 3.4e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDP41853.1 - 8.2e-22 78.0 0.0 2.7e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDP41853.1 - 3.4e-12 45.9 4.0 3e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDP41853.1 - 9.4e-09 34.6 7.7 0.00077 18.4 3.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDP41853.1 - 7.4e-05 22.7 0.1 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDP41853.1 - 0.00025 20.2 1.1 0.00045 19.3 0.5 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EDP41853.1 - 0.00047 20.1 2.4 0.0017 18.3 1.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EDP41853.1 - 0.00054 19.1 1.1 0.00076 18.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EDP41853.1 - 0.024 15.0 0.6 0.12 12.8 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDP41853.1 - 0.024 13.7 3.3 3.5 6.6 3.3 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDP41853.1 - 0.024 13.5 0.1 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EDP41853.1 - 0.051 13.2 0.5 0.097 12.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EDP41853.1 - 0.099 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.17 EDP41853.1 - 0.23 10.2 0.4 0.4 9.4 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDP41853.1 - 0.43 10.6 2.3 13 5.7 1.0 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDP41853.1 - 0.56 9.5 3.8 1.1 8.6 2.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EDP41853.1 - 0.61 8.4 3.0 0.43 8.9 0.9 1.6 2 0 0 2 2 2 0 HI0933-like protein Bin3 PF06859.7 EDP41854.1 - 8.9e-23 80.3 0.0 1.4e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 EDP41854.1 - 8.1e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41854.1 - 1.2e-07 32.3 0.0 2.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP41854.1 - 0.00018 21.8 0.0 0.0021 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP41854.1 - 0.00041 19.9 0.0 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP41854.1 - 0.0024 17.9 0.0 0.0051 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41854.1 - 0.0035 17.7 0.0 2 8.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain FmrO PF07091.6 EDP41854.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RNA_pol PF00940.14 EDP41855.1 - 6.2e-157 522.2 0.0 8.8e-157 521.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EDP41855.1 - 6e-79 265.5 2.1 6e-79 265.5 1.4 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Macoilin PF09726.4 EDP41855.1 - 0.087 11.0 9.0 0.13 10.4 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PPR_2 PF13041.1 EDP41855.1 - 0.2 11.6 0.1 31 4.6 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family PPR_3 PF13812.1 EDP41855.1 - 0.45 10.9 3.2 33 5.1 0.2 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Sod_Fe_C PF02777.13 EDP41856.1 - 7e-36 122.2 0.2 1.2e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDP41856.1 - 6.6e-31 106.4 2.1 8.2e-31 106.1 0.4 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SET PF00856.23 EDP41858.1 - 1.2e-22 81.0 0.4 1.2e-22 81.0 0.3 3.7 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EDP41858.1 - 1.6e-06 27.9 11.3 0.0017 18.2 0.1 3.5 3 0 0 3 3 3 2 SRI (Set2 Rpb1 interacting) domain Selenoprotein_S PF06936.6 EDP41858.1 - 1.2 8.6 20.9 1.7 8.1 11.8 2.6 2 0 0 2 2 2 0 Selenoprotein S (SelS) XPA_C PF05181.7 EDP41859.1 - 3.8e-27 93.6 1.2 6.4e-27 92.8 0.9 1.4 1 0 0 1 1 1 1 XPA protein C-terminus GFA PF04828.9 EDP41859.1 - 0.0032 17.3 0.9 5.4 7.0 0.0 3.3 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.27 EDP41861.1 - 0.00022 20.9 0.3 4.6 7.2 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EDP41861.1 - 0.0033 16.7 0.4 0.077 12.3 0.0 3.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature FA_desaturase PF00487.19 EDP41862.1 - 3.4e-32 111.8 24.8 3.4e-32 111.8 17.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Mus7 PF09462.5 EDP41863.1 - 3.9e-82 277.0 0.1 5.5e-82 276.5 0.1 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family RhoGEF PF00621.15 EDP41864.1 - 2.9e-24 85.9 0.9 1e-22 80.9 0.0 2.5 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EDP41864.1 - 4e-18 65.0 10.5 9.1e-18 63.9 7.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EDP41864.1 - 2.1e-06 27.8 0.0 8.3e-06 25.9 0.0 2.1 2 1 0 2 2 2 1 PH domain Cytadhesin_P30 PF07271.6 EDP41865.1 - 0.0059 15.9 46.1 0.0078 15.5 31.9 1.1 1 0 0 1 1 1 1 Cytadhesin P30/P32 Collagen PF01391.13 EDP41865.1 - 0.34 10.4 11.2 0.57 9.7 7.8 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) CTD_bind PF04818.8 EDP41866.1 - 0.0026 17.9 0.0 0.021 15.0 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase II-binding domain. SRP9-21 PF05486.7 EDP41867.1 - 7.3e-11 41.6 0.9 7.7e-11 41.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Ribosomal_L24e PF01246.15 EDP41868.1 - 3.1e-05 23.7 3.3 3.4e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e Flu_M1 PF00598.14 EDP41868.1 - 0.038 13.3 0.9 0.048 13.0 0.6 1.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) WD40 PF00400.27 EDP41869.1 - 1.7e-33 113.2 5.3 5.8e-08 32.3 0.0 5.3 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EDP41869.1 - 0.0059 14.7 3.1 3.2 5.7 2.2 3.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PRP4 PF08799.6 EDP41870.1 - 7.9e-10 37.8 1.5 1.6e-09 36.8 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40 PF00400.27 EDP41870.1 - 0.00017 21.3 0.1 0.00045 20.0 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Nbas_N PF15492.1 EDP41870.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal tRNA-synt_2d PF01409.15 EDP41871.1 - 8e-86 287.2 0.0 1.1e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDP41871.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EDP41871.1 - 0.00038 19.3 0.6 0.0024 16.6 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Peptidase_M3 PF01432.15 EDP41872.1 - 6.6e-131 437.4 0.0 8.1e-131 437.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 MFS_1 PF07690.11 EDP41874.1 - 3.5e-44 150.9 30.9 4.5e-44 150.6 21.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP41874.1 - 4.9e-13 48.4 13.1 4.9e-13 48.4 9.1 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EDP41874.1 - 4.1e-07 28.4 0.3 8.8e-07 27.3 0.2 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 EDP41874.1 - 4.5e-06 25.1 1.7 6.4e-06 24.6 1.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EDP41874.1 - 0.0028 15.8 2.8 0.0028 15.8 1.9 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector ESSS PF10183.4 EDP41874.1 - 0.58 10.5 1.6 0.94 9.9 0.3 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 EDP41875.1 - 2.3e-20 72.6 19.4 3.9e-11 42.2 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EDP41875.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sugar_tr PF00083.19 EDP41875.1 - 9.3 4.6 15.7 0.23 10.0 0.3 3.6 3 1 1 4 4 4 0 Sugar (and other) transporter Lipase_3 PF01764.20 EDP41876.1 - 4.6e-27 94.3 0.0 5.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EDP41876.1 - 2.8e-07 30.1 0.0 1.9e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EDP41876.1 - 6.8e-05 22.8 0.0 9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP41876.1 - 0.0026 17.5 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDP41876.1 - 0.037 12.5 0.0 0.054 11.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EDP41876.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EDP41876.1 - 0.044 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.8 EDP41876.1 - 0.063 12.7 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF676 PF05057.9 EDP41876.1 - 0.095 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 EDP41876.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase MFS_1 PF07690.11 EDP41877.1 - 7.1e-31 107.1 37.7 1.5e-29 102.8 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_7 PF03441.9 EDP41878.1 - 2.2e-89 299.3 3.6 5.4e-89 298.0 2.5 1.6 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase GMC_oxred_N PF00732.14 EDP41879.1 - 7.3e-48 163.2 0.3 9.6e-48 162.8 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDP41879.1 - 5e-29 101.4 0.0 9.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDP41879.1 - 6.7e-07 28.5 0.6 0.0016 17.3 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDP41879.1 - 7.8e-05 22.6 1.8 0.0002 21.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDP41879.1 - 0.00095 19.0 0.2 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDP41879.1 - 0.012 14.5 1.8 0.22 10.3 0.4 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDP41879.1 - 0.041 12.3 0.3 1.5 7.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EDP41879.1 - 0.053 12.4 0.1 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EDP41879.1 - 0.084 11.9 0.0 0.48 9.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Asp PF00026.18 EDP41880.1 - 1.2e-11 44.4 0.0 1.4e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EDP41880.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ADH_zinc_N PF00107.21 EDP41882.1 - 1.5e-20 73.0 0.1 2.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP41882.1 - 1.4e-16 60.2 0.7 5.8e-16 58.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EDP41882.1 - 0.0067 16.9 0.0 0.037 14.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Asp PF00026.18 EDP41884.1 - 7.1e-34 117.4 0.0 4.4e-33 114.8 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP41884.1 - 0.00048 20.5 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EDP41884.1 - 0.0017 18.3 0.0 0.016 15.1 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EDP41884.1 - 0.023 14.5 0.0 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 EDP41884.1 - 0.029 13.9 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal His_Phos_2 PF00328.17 EDP41886.1 - 4.1e-13 49.3 0.0 1.8e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Metallophos PF00149.23 EDP41887.1 - 2.9e-09 36.6 1.6 5.4e-09 35.7 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDP41887.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Amidase PF01425.16 EDP41888.1 - 8e-85 285.3 0.0 1.1e-84 284.8 0.0 1.2 1 0 0 1 1 1 1 Amidase EVE PF01878.13 EDP41891.1 - 6.9e-41 139.6 0.0 8.6e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 EVE domain DUF1891 PF09004.5 EDP41891.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Pkinase PF00069.20 EDP41892.1 - 2.9e-53 180.6 0.0 2.1e-46 158.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP41892.1 - 9.3e-23 80.6 0.0 4.4e-19 68.5 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDP41892.1 - 8.1e-05 21.7 0.0 0.00023 20.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP41892.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP41892.1 - 0.043 13.5 0.1 0.09 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RasGAP PF00616.14 EDP41893.1 - 1e-40 139.4 0.1 3.4e-40 137.8 0.0 1.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EDP41893.1 - 3.6e-10 39.6 1.2 1.2e-09 38.0 0.9 1.9 1 0 0 1 1 1 1 RasGAP C-terminus Cep57_MT_bd PF06657.8 EDP41893.1 - 0.063 13.2 1.0 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_L13e PF01294.13 EDP41894.1 - 3.7e-62 208.9 4.5 5.4e-62 208.4 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Peptidase_M76 PF09768.4 EDP41895.1 - 1.2e-66 223.4 0.1 1.4e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 EDP41895.1 - 0.046 13.9 1.6 4.1 7.7 0.1 2.3 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus SprT-like PF10263.4 EDP41895.1 - 0.18 11.4 2.7 0.45 10.1 1.9 1.7 1 1 0 1 1 1 0 SprT-like family SNARE PF05739.14 EDP41896.1 - 0.00044 19.8 0.2 0.00044 19.8 0.1 2.3 3 1 0 3 3 3 1 SNARE domain Lebercilin PF15619.1 EDP41896.1 - 0.00056 19.3 5.3 0.0007 19.0 3.7 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease V-SNARE_C PF12352.3 EDP41896.1 - 0.022 14.8 1.6 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Prefoldin_3 PF13758.1 EDP41896.1 - 0.12 12.1 3.7 1.8 8.3 0.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit MutS_V PF00488.16 EDP41897.1 - 1.6e-93 312.4 0.0 2.9e-93 311.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDP41897.1 - 5.2e-30 104.7 0.2 1.4e-29 103.3 0.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EDP41897.1 - 5.4e-16 58.5 0.1 1.6e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EDP41897.1 - 9.2e-16 58.1 0.3 4.9e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EDP41897.1 - 3.5e-15 56.0 0.0 6.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain I ING PF12998.2 EDP41898.1 - 6.8e-10 39.1 1.7 1.3e-09 38.2 1.2 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EDP41898.1 - 3.6e-08 32.9 11.3 7.1e-08 32.0 7.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EDP41898.1 - 0.73 10.0 5.7 0.19 11.8 1.3 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain PLDc_2 PF13091.1 EDP41899.1 - 7.2e-12 45.1 0.0 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDP41899.1 - 2e-07 30.5 4.1 0.012 15.4 0.2 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif Gcd10p PF04189.8 EDP41901.1 - 1.1e-43 149.5 0.0 6.3e-27 94.4 0.0 2.2 1 1 1 2 2 2 2 Gcd10p family Glutenin_hmw PF03157.8 EDP41902.1 - 0.021 13.1 0.5 0.021 13.1 0.4 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit Mpp10 PF04006.7 EDP41903.1 - 6.5e-87 292.3 116.1 1.1e-76 258.5 28.8 4.0 1 1 1 3 3 3 2 Mpp10 protein Aminotran_3 PF00202.16 EDP41904.1 - 3e-39 134.8 0.0 2.4e-18 66.1 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EDP41904.1 - 7.1e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF0240 PF06784.6 EDP41905.1 - 0.73 9.4 3.5 0.3 10.7 0.1 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0240) TPR_1 PF00515.23 EDP41907.1 - 1.3e-30 103.7 13.5 5.8e-06 25.6 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EDP41907.1 - 7.5e-27 92.7 18.4 2.1e-11 43.3 0.3 5.5 4 1 2 6 6 6 5 TPR repeat TPR_2 PF07719.12 EDP41907.1 - 1.7e-23 80.5 19.1 0.0011 18.7 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDP41907.1 - 6.8e-20 69.3 3.4 0.0008 19.0 0.0 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDP41907.1 - 2.8e-17 61.6 12.9 0.0037 17.7 0.0 8.0 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDP41907.1 - 1.9e-15 55.7 5.2 0.00071 19.5 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat APC8 PF04049.8 EDP41907.1 - 5e-15 55.4 0.7 5.6e-14 52.0 0.5 2.3 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_16 PF13432.1 EDP41907.1 - 3.1e-14 53.1 19.5 6e-05 23.5 0.4 6.5 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDP41907.1 - 3.2e-14 52.6 15.1 1.4e-06 28.0 0.1 5.9 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EDP41907.1 - 4.7e-12 44.7 10.4 0.0041 16.8 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_15 PF13429.1 EDP41907.1 - 2.8e-10 39.7 7.2 0.0043 16.1 0.1 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP41907.1 - 4e-09 36.6 3.0 0.032 14.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP41907.1 - 2.2e-08 33.8 18.3 0.00012 21.8 0.4 5.4 3 1 4 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EDP41907.1 - 2.6e-08 33.8 12.5 0.0067 16.5 0.0 4.5 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDP41907.1 - 3.8e-05 23.8 6.8 1.9 9.1 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.5 EDP41907.1 - 6.8e-05 21.7 0.1 0.00041 19.2 0.0 2.0 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 EDP41907.1 - 0.34 11.2 6.7 2.1 8.6 2.0 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.13 EDP41907.1 - 0.43 10.5 5.0 1.2 9.0 0.1 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain FHA PF00498.21 EDP41908.1 - 1.2e-16 60.5 0.5 3.8e-16 58.9 0.0 2.2 3 0 0 3 3 3 1 FHA domain Ribosomal_L38e PF01781.13 EDP41909.1 - 8.6e-32 108.7 2.8 9.8e-32 108.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Ribosomal_S11 PF00411.14 EDP41910.1 - 2.2e-40 137.2 0.2 2.6e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 EDP41910.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) CS PF04969.11 EDP41911.1 - 7.5e-17 61.6 0.0 1.8e-16 60.4 0.0 1.6 2 0 0 2 2 2 1 CS domain SNF2_N PF00176.18 EDP41912.1 - 3.8e-51 173.6 0.0 5.4e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EDP41912.1 - 4.1e-10 39.4 0.0 6.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDP41912.1 - 2.5e-05 24.1 0.0 6.2e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2439 PF10382.4 EDP41912.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Bac_surface_Ag PF01103.18 EDP41913.1 - 1.4e-22 80.5 0.0 1.4e-17 64.1 0.0 2.1 1 1 1 2 2 2 2 Surface antigen RNA_pol_Rbc25 PF08292.7 EDP41914.1 - 2.9e-33 114.6 0.0 4.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDP41914.1 - 2.4e-20 72.4 0.1 1.4e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RhoGAP PF00620.22 EDP41915.1 - 7.8e-17 61.2 0.7 1.2e-16 60.6 0.5 1.3 1 0 0 1 1 1 1 RhoGAP domain Vps8 PF12816.2 EDP41916.1 - 1.1e-59 200.9 0.4 2.9e-59 199.6 0.3 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 EDP41916.1 - 0.0063 16.3 0.4 0.028 14.3 0.3 2.2 1 0 0 1 1 1 1 WD domain, G-beta repeat MdcE PF06833.6 EDP41916.1 - 0.0095 15.1 1.2 0.12 11.6 0.1 2.2 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Peptidase_M41 PF01434.13 EDP41917.1 - 2.7e-68 229.6 0.1 1.7e-67 226.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EDP41917.1 - 2.3e-42 144.3 0.0 4.5e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDP41917.1 - 2e-10 40.8 0.1 6.5e-10 39.1 0.0 1.9 2 0 0 2 2 1 1 FtsH Extracellular AAA_22 PF13401.1 EDP41917.1 - 0.00084 19.4 0.0 0.33 11.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDP41917.1 - 0.0021 17.7 0.5 0.0069 16.1 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDP41917.1 - 0.0025 18.6 0.0 0.0074 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP41917.1 - 0.0059 16.9 1.3 0.72 10.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDP41917.1 - 0.0063 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDP41917.1 - 0.017 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDP41917.1 - 0.021 14.5 0.0 0.094 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDP41917.1 - 0.029 14.3 2.7 0.19 11.6 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 EDP41917.1 - 0.031 13.3 0.0 0.088 11.8 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EDP41917.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EDP41917.1 - 0.084 12.2 0.3 0.28 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain PC_rep PF01851.17 EDP41920.1 - 5.1e-20 70.5 12.3 1e-06 28.6 0.0 8.8 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HhH-GPD PF00730.20 EDP41921.1 - 1.1e-14 54.5 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDP41921.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 EDP41921.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain Aa_trans PF01490.13 EDP41923.1 - 4.9e-54 183.3 20.3 6.5e-54 182.9 14.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Nsp1_C PF05064.8 EDP41924.1 - 9.1e-31 105.9 0.2 1.8e-30 104.9 0.2 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EDP41924.1 - 7.5e-16 58.3 145.6 2.5e-07 30.9 29.7 4.9 1 1 3 4 4 4 3 Nucleoporin FG repeat region TACC PF05010.9 EDP41924.1 - 0.0015 18.3 0.5 0.0023 17.7 0.3 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) LTXXQ PF07813.7 EDP41924.1 - 0.0025 18.2 6.4 0.0054 17.1 4.4 1.5 1 0 0 1 1 1 1 LTXXQ motif family protein DUF4201 PF13870.1 EDP41924.1 - 0.013 14.9 1.6 0.026 13.9 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Lipoprotein_7 PF01540.11 EDP41924.1 - 0.033 13.2 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Tropomyosin PF00261.15 EDP41924.1 - 0.11 11.5 3.3 0.17 10.9 2.3 1.1 1 0 0 1 1 1 0 Tropomyosin Glyco_transf_54 PF04666.8 EDP41924.1 - 0.13 10.9 0.3 0.2 10.3 0.2 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Atg14 PF10186.4 EDP41924.1 - 0.16 10.8 1.6 0.29 10.0 1.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EDP41924.1 - 1.2 8.7 5.3 0.48 9.9 1.9 1.6 2 0 0 2 2 2 0 IncA protein Proteasome PF00227.21 EDP41925.1 - 8.7e-28 96.8 0.0 1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Peptidase_S9 PF00326.16 EDP41926.1 - 2.6e-49 167.3 0.1 4.2e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDP41926.1 - 2.1e-10 40.5 0.3 3.8e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDP41926.1 - 0.078 11.4 0.0 2.1 6.7 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EDP41926.1 - 0.083 12.4 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Rep_fac_C PF08542.6 EDP41927.1 - 1.5e-19 69.7 0.0 5.8e-19 67.8 0.0 2.0 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDP41927.1 - 5.2e-09 35.9 0.1 8.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit SNF2_N PF00176.18 EDP41927.1 - 0.059 12.1 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Aminotran_1_2 PF00155.16 EDP41928.1 - 2.1e-37 128.9 0.0 2.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SET PF00856.23 EDP41929.1 - 3.3e-07 30.7 0.0 6.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 SET domain Peripla_BP_1 PF00532.16 EDP41929.1 - 0.057 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Fels1 PF05666.6 EDP41929.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like IBR PF01485.16 EDP41929.1 - 1.9 8.4 13.2 6.9 6.6 8.3 2.3 1 1 1 2 2 2 0 IBR domain Actin PF00022.14 EDP41930.1 - 4.6e-51 173.4 0.0 6.1e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDP41930.1 - 0.04 12.5 0.0 0.29 9.6 0.0 2.2 3 0 0 3 3 3 0 MreB/Mbl protein PilM_2 PF11104.3 EDP41930.1 - 0.052 12.4 0.0 7.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; HSP70 PF00012.15 EDP41930.1 - 0.13 10.1 0.0 0.35 8.7 0.0 1.5 2 0 0 2 2 2 0 Hsp70 protein Pro_isomerase PF00160.16 EDP41931.1 - 7.8e-49 165.8 0.2 9.1e-49 165.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mss4 PF04421.8 EDP41932.1 - 1.5e-06 27.9 0.0 0.0099 15.6 0.0 2.6 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 EDP41932.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDP41932.1 - 0.0081 16.3 0.1 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TRAM_LAG1_CLN8 PF03798.11 EDP41933.1 - 4e-34 117.9 31.5 4e-34 117.9 21.8 1.9 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 EDP41933.1 - 4.4e-15 54.9 0.3 1.6e-13 49.9 0.2 2.9 1 1 0 1 1 1 1 TRAM1-like protein DnaJ PF00226.26 EDP41934.1 - 1.2e-15 56.9 5.0 1.3e-15 56.8 2.6 1.7 2 0 0 2 2 2 1 DnaJ domain RecO_C PF02565.10 EDP41934.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Recombination protein O C terminal RPT PF13446.1 EDP41934.1 - 0.065 12.6 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein NAGLU_C PF12972.2 EDP41934.1 - 0.091 12.1 0.2 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DEAD PF00270.24 EDP41935.1 - 1.9e-38 131.5 0.0 3.6e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP41935.1 - 1.1e-11 44.3 0.0 3.5e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP41935.1 - 3.3e-09 36.8 0.0 5.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDP41935.1 - 0.013 15.2 0.1 0.075 12.7 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain Flavi_DEAD PF07652.9 EDP41935.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 EDP41935.1 - 0.091 12.9 0.4 3.1 7.9 0.3 2.7 1 1 0 1 1 1 0 AAA domain Cyt-b5 PF00173.23 EDP41936.1 - 4.7e-22 77.5 0.1 9e-22 76.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EDP41936.1 - 4.2e-10 40.0 21.4 4.2e-10 40.0 14.8 2.4 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Lactamase_B_2 PF12706.2 EDP41937.1 - 1.9e-30 105.8 0.1 4.4e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EDP41937.1 - 2.3e-15 55.8 0.0 2.4e-14 52.5 0.0 2.7 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EDP41937.1 - 1.5e-07 31.2 0.1 1.1e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily PH PF00169.24 EDP41938.1 - 1.6e-06 28.2 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Ribosomal_60s PF00428.14 EDP41938.1 - 1.1e-05 25.7 7.0 2.8e-05 24.4 4.9 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EDP41938.1 - 0.041 13.3 8.2 0.074 12.5 5.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EDP41938.1 - 0.055 12.6 4.3 0.12 11.5 3.0 1.6 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.3 EDP41938.1 - 0.22 11.4 8.9 0.1 12.5 4.2 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 EDP41938.1 - 0.23 10.6 3.0 0.37 10.0 2.1 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EDP41938.1 - 0.38 10.9 11.2 0.87 9.8 7.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EDP41938.1 - 0.65 8.6 8.7 1.1 7.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.27 EDP41939.1 - 1.9e-62 205.0 21.9 2.2e-11 43.1 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EDP41939.1 - 2.3e-08 33.9 0.1 0.022 14.4 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDP41939.1 - 0.00082 17.3 0.0 0.58 7.8 0.0 2.5 2 1 1 3 3 3 2 IKI3 family Gaa1 PF04114.9 EDP41940.1 - 1.2e-46 159.4 12.3 6.6e-23 81.1 0.0 3.9 2 2 0 2 2 2 2 Gaa1-like, GPI transamidase component Methyltransf_23 PF13489.1 EDP41941.1 - 4.5e-23 81.7 0.0 6.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP41941.1 - 7.2e-16 58.4 0.0 1.7e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP41941.1 - 1.5e-13 50.6 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41941.1 - 2.2e-13 50.7 0.0 1.4e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP41941.1 - 3.2e-13 49.9 0.0 6.2e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP41941.1 - 5.4e-07 29.8 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDP41941.1 - 1.5e-06 27.5 0.0 3.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EDP41941.1 - 2.2e-06 27.7 0.3 5.3e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDP41941.1 - 0.00014 20.7 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EDP41941.1 - 0.00021 20.4 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EDP41941.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EDP41941.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EDP41941.1 - 0.12 11.7 0.4 0.21 10.9 0.3 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.6 EDP41941.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CLU PF13236.1 EDP41942.1 - 1.2e-73 247.2 0.0 1.8e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EDP41942.1 - 2.6e-47 160.9 0.0 5.1e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EDP41942.1 - 2.4e-17 62.6 0.9 4.6e-08 32.8 0.0 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDP41942.1 - 5.8e-14 51.4 5.2 3e-05 23.7 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 EDP41942.1 - 2.2e-08 34.0 0.0 4.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_11 PF13414.1 EDP41942.1 - 0.00065 19.2 2.8 0.024 14.2 0.1 3.3 3 0 0 3 3 3 1 TPR repeat HMG-CoA_red PF00368.13 EDP41943.1 - 2.2e-158 526.8 2.8 2.8e-158 526.4 2.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EDP41943.1 - 1e-14 54.2 5.1 5.7e-09 35.6 0.3 2.8 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation IgaA PF07095.6 EDP41943.1 - 0.0025 15.6 0.6 0.0046 14.8 0.4 1.3 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA Patched PF02460.13 EDP41943.1 - 0.0057 14.6 0.0 0.0098 13.8 0.0 1.3 1 0 0 1 1 1 1 Patched family AMP-binding PF00501.23 EDP41945.1 - 1.3e-85 287.3 0.0 1.7e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDP41945.1 - 0.0042 18.0 0.0 0.015 16.2 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain DJ-1_PfpI PF01965.19 EDP41946.1 - 3.7e-17 62.1 0.1 4.9e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EDP41946.1 - 1.2e-09 37.6 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EDP41946.1 - 0.016 14.8 0.7 0.074 12.6 0.1 2.0 1 1 1 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Sec63 PF02889.11 EDP41947.1 - 4.1e-172 571.5 0.0 3.4e-90 302.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDP41947.1 - 7.8e-47 158.9 0.0 4.1e-28 97.9 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EDP41947.1 - 4.6e-13 49.4 0.0 5.9e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDP41947.1 - 3.1e-12 46.1 0.0 1.9e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDP41947.1 - 9.2e-05 21.3 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SET PF00856.23 EDP41948.1 - 6.2e-12 46.1 1.0 3.7e-10 40.3 0.0 3.7 3 2 0 3 3 3 1 SET domain PHD PF00628.24 EDP41948.1 - 3.3e-07 29.8 14.5 6.4e-07 28.9 10.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDP41948.1 - 0.012 14.9 7.7 0.024 13.9 5.3 1.5 1 0 0 1 1 1 0 PHD-finger HEAT_EZ PF13513.1 EDP41949.1 - 0.029 14.8 13.0 0.37 11.3 0.1 6.3 6 1 1 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.1 EDP41949.1 - 0.13 12.5 7.6 5.6 7.3 0.1 5.1 4 1 0 5 5 5 0 HEAT repeats GDI PF00996.13 EDP41949.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor HEAT PF02985.17 EDP41949.1 - 1.3 9.2 7.2 59 4.1 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat Anticodon_1 PF08264.8 EDP41950.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PG_binding_1 PF01471.13 EDP41950.1 - 0.057 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain PCI PF01399.22 EDP41951.1 - 0.031 14.5 0.1 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 PCI domain UvrD-helicase PF00580.16 EDP41952.1 - 4.8e-13 49.1 0.0 5.1e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EDP41952.1 - 2.3e-11 43.7 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 EDP41952.1 - 9.3e-10 38.5 0.0 2.9e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EDP41952.1 - 4e-08 33.0 0.1 0.037 13.5 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EDP41952.1 - 9.1e-07 28.6 0.0 0.00045 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EDP41952.1 - 6e-06 25.9 0.0 1.9e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EDP41952.1 - 3.4e-05 23.1 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.1 EDP41952.1 - 0.00038 20.5 0.0 0.66 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP41952.1 - 0.022 14.7 0.5 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_12 PF13087.1 EDP41952.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain BolA PF01722.13 EDP41953.1 - 7.7e-18 64.2 1.0 1.8e-17 63.0 0.1 2.0 3 0 0 3 3 3 1 BolA-like protein DUF605 PF04652.11 EDP41953.1 - 5.8 6.2 15.0 7.5 5.8 10.4 1.1 1 0 0 1 1 1 0 Vta1 like CN_hydrolase PF00795.17 EDP41954.1 - 0.00013 21.4 0.0 0.00068 19.0 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase RNA_pol_Rpb5_C PF01191.14 EDP41954.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DEAD PF00270.24 EDP41956.1 - 2.5e-20 72.6 0.0 5.8e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EDP41956.1 - 6.2e-20 71.7 0.0 1.8e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDP41956.1 - 2e-17 62.8 0.2 4.3e-17 61.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NPR3 PF03666.8 EDP41957.1 - 3.8e-58 197.1 10.4 3.9e-48 164.1 5.2 3.0 3 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EDP41957.1 - 2.4e-06 26.5 0.2 7.1e-05 21.6 0.0 2.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 FAM92 PF06730.6 EDP41957.1 - 0.16 11.2 1.4 9.5 5.4 0.1 2.4 2 0 0 2 2 2 0 FAM92 protein Drf_GBD PF06371.8 EDP41958.1 - 3.7e-11 42.7 0.0 7.2e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Kinesin PF00225.18 EDP41959.1 - 8.3e-104 346.8 0.1 1.3e-103 346.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Bac_DnaA PF00308.13 EDP41959.1 - 0.089 12.4 0.4 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein PapD-like PF14874.1 EDP41960.1 - 0.027 14.4 0.2 1 9.3 0.1 2.6 2 0 0 2 2 2 0 Flagellar-associated PapD-like PapD-like PF14874.1 EDP41961.1 - 5.6e-08 32.6 0.0 0.0021 17.9 0.1 3.5 3 0 0 3 3 3 3 Flagellar-associated PapD-like Vps39_1 PF10366.4 EDP41962.1 - 3.9e-24 84.7 0.1 1.9e-23 82.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EDP41962.1 - 1.2e-22 80.0 0.2 7.7e-22 77.5 0.3 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EDP41962.1 - 3.8e-11 42.7 0.1 1.5e-05 24.6 0.0 3.1 4 0 0 4 4 4 2 Region in Clathrin and VPS CNH PF00780.17 EDP41962.1 - 7.5e-07 28.8 0.0 5.8e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 CNH domain PPR PF01535.15 EDP41962.1 - 0.14 12.1 0.4 78 3.5 0.0 4.0 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.1 EDP41962.1 - 0.24 11.2 3.5 18 5.4 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDP41962.1 - 2.6 8.0 7.0 13 5.7 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EDP41963.1 - 1.1e-46 159.4 0.0 1.3e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDP41963.1 - 0.0048 15.2 0.0 0.0081 14.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EDP41963.1 - 0.012 14.7 0.0 0.22 10.5 0.0 2.4 2 1 0 2 2 2 0 Beta-eliminating lyase DUF2611 PF11022.3 EDP41964.1 - 0.14 12.2 0.1 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2611) Peptidase_M1 PF01433.15 EDP41966.1 - 1.2e-93 314.3 0.4 1e-90 304.6 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDP41966.1 - 2.3e-44 151.9 2.2 3.5e-44 151.3 1.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDP41966.1 - 2.3e-15 56.7 0.4 5.7e-15 55.4 0.3 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M1 PF01433.15 EDP41967.1 - 8.4e-93 311.5 0.1 1.8e-61 208.3 0.3 2.2 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EDP41967.1 - 4.1e-58 197.1 1.3 5.8e-58 196.6 0.9 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDP41967.1 - 1.8e-13 50.6 0.2 5.6e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M1 PF01433.15 EDP41968.1 - 2.1e-107 359.5 0.0 8.3e-68 229.2 0.1 2.4 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EDP41968.1 - 3.6e-60 203.9 0.4 5.5e-60 203.3 0.3 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDP41968.1 - 8.4e-14 51.7 0.3 3e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase MA superfamily SEP PF08059.8 EDP41969.1 - 1.8e-25 89.0 0.0 6.4e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EDP41969.1 - 0.0052 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Pap_E4 PF02711.9 EDP41969.1 - 6.3 7.6 6.3 2.5 8.9 0.8 2.7 2 1 0 2 2 2 0 E4 protein Mito_carr PF00153.22 EDP41970.1 - 1.5e-38 130.3 3.9 1.7e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Ras PF00071.17 EDP41971.1 - 5.4e-41 139.6 0.2 6.4e-41 139.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP41971.1 - 1.5e-11 44.7 0.0 2.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP41971.1 - 1e-09 37.9 0.1 5.2e-09 35.5 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDP41971.1 - 0.00027 20.4 0.1 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDP41971.1 - 0.00053 19.1 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PP_M1 PF03012.9 EDP41971.1 - 0.016 14.5 0.1 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein SWIB PF02201.13 EDP41972.1 - 9.7e-13 47.6 0.0 2.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_S9 PF00380.14 EDP41973.1 - 5.4e-41 139.6 0.1 6.1e-41 139.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.17 EDP41974.1 - 8.7e-58 194.8 0.0 1.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family NUFIP1 PF10453.4 EDP41975.1 - 1e-10 40.9 0.0 2.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Nop14 PF04147.7 EDP41975.1 - 0.02 12.8 8.7 0.03 12.2 6.1 1.2 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.6 EDP41975.1 - 0.029 12.5 3.3 0.034 12.2 2.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EDP41975.1 - 6.6 4.8 11.1 9 4.4 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC_tran PF00005.22 EDP41976.1 - 2.5e-45 154.1 0.0 8.4e-27 94.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDP41976.1 - 1.7e-40 139.1 28.5 1.6e-24 86.7 8.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDP41976.1 - 8.3e-13 48.0 0.6 0.024 13.8 0.0 4.6 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP41976.1 - 5.8e-10 39.6 0.0 0.034 14.1 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EDP41976.1 - 1e-08 35.3 4.1 0.0026 17.7 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 EDP41976.1 - 1.5e-08 34.0 0.0 6.4e-05 22.4 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDP41976.1 - 1.2e-07 32.2 0.1 0.0098 16.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EDP41976.1 - 1.4e-05 24.1 0.0 0.026 13.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EDP41976.1 - 2.3e-05 24.5 0.1 0.41 10.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EDP41976.1 - 9.5e-05 21.9 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EDP41976.1 - 9.7e-05 21.6 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDP41976.1 - 0.00024 21.0 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EDP41976.1 - 0.0005 18.7 0.0 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EDP41976.1 - 0.00077 18.6 0.1 0.4 9.7 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin cobW PF02492.14 EDP41976.1 - 0.002 17.5 0.8 0.3 10.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EDP41976.1 - 0.0035 17.8 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EDP41976.1 - 0.0065 15.8 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP41976.1 - 0.01 15.4 0.4 17 5.0 0.1 3.4 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 EDP41976.1 - 0.011 15.4 0.1 1.8 8.2 0.0 3.3 4 0 0 4 4 3 0 Archaeal ATPase AAA PF00004.24 EDP41976.1 - 0.032 14.4 0.0 6.3 7.0 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDP41976.1 - 0.032 13.6 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EDP41976.1 - 0.038 14.1 0.0 11 6.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.9 EDP41976.1 - 0.044 13.5 0.3 4 7.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EDP41976.1 - 0.064 13.0 0.6 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EDP41976.1 - 0.067 13.0 0.0 4.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EDP41976.1 - 0.068 12.6 0.0 8.8 5.7 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase MobB PF03205.9 EDP41976.1 - 0.071 12.8 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EDP41976.1 - 0.081 12.5 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EDP41976.1 - 0.12 11.9 0.0 9.1 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDP41976.1 - 0.12 13.1 0.0 1.9 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EDP41976.1 - 0.13 12.0 0.0 4 7.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Bac_DnaA PF00308.13 EDP41976.1 - 0.16 11.5 0.1 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_18 PF13238.1 EDP41976.1 - 0.27 11.5 0.0 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain GCV_T PF01571.16 EDP41977.1 - 1.5e-59 200.9 0.1 1.9e-59 200.6 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDP41977.1 - 9e-26 89.7 0.0 2.7e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EDP41977.1 - 0.033 14.0 0.1 0.14 12.0 0.0 2.0 2 1 0 2 2 2 0 Sarcosine oxidase, gamma subunit family LRR_4 PF12799.2 EDP41978.1 - 1.5e-14 53.2 14.0 2.5e-07 30.1 2.9 4.8 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP41978.1 - 1.9e-14 53.1 18.5 1.1e-10 41.0 5.0 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EDP41978.1 - 1.2e-09 36.8 16.6 0.064 13.3 0.3 7.5 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 EDP41978.1 - 1.2e-07 31.0 10.7 2.5 8.4 0.1 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EDP41978.1 - 4.2e-05 23.0 20.2 1.2 9.6 0.1 7.4 7 0 0 7 7 7 1 Leucine rich repeat zf-CCCH PF00642.19 EDP41978.1 - 4.8e-05 22.9 7.4 0.0011 18.5 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RAM PF15320.1 EDP41978.1 - 0.33 11.2 3.6 21 5.4 0.0 2.7 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein DUF2763 PF10961.3 EDP41978.1 - 7.7 6.9 7.4 32 5.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Sugar_tr PF00083.19 EDP41979.1 - 2e-14 53.0 22.2 1.5e-12 46.9 15.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter WD40 PF00400.27 EDP41980.1 - 1.7e-45 151.2 17.6 4.5e-09 35.8 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat HARP PF07443.8 EDP41980.1 - 0.043 13.2 0.7 1.1 8.7 0.1 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) CHCH PF06747.8 EDP41981.1 - 3.3e-08 33.2 4.5 6.3e-08 32.3 3.1 1.5 1 0 0 1 1 1 1 CHCH domain Tom5 PF10642.4 EDP41981.1 - 0.035 13.7 0.3 0.035 13.7 0.2 2.4 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase adh_short PF00106.20 EDP41982.1 - 5.3e-07 29.7 0.0 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Ytp1 PF10355.4 EDP41983.1 - 1.4e-69 234.3 10.4 1.7e-69 234.0 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) SAM_1 PF00536.25 EDP41984.1 - 8.7e-17 61.0 0.0 1.6e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDP41984.1 - 1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EDP41984.1 - 4.3e-08 32.4 0.0 3.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 SH3 domain RA PF00788.18 EDP41984.1 - 2.9e-06 27.6 0.0 5.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.1 EDP41984.1 - 3.1e-06 26.6 0.3 0.0033 16.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EDP41984.1 - 0.0067 15.8 0.7 1.3 8.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SAM_PNT PF02198.11 EDP41984.1 - 0.0099 15.6 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Sec7 PF01369.15 EDP41985.1 - 5.5e-17 62.0 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Cullin PF00888.17 EDP41986.1 - 1e-21 77.1 0.0 1.9e-21 76.2 0.0 1.4 2 0 0 2 2 2 1 Cullin family DUF2201 PF09967.4 EDP41986.1 - 0.078 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) RmlD_sub_bind PF04321.12 EDP41987.1 - 5.8e-55 186.1 0.0 9.6e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Vps5 PF09325.5 EDP41987.1 - 1.9e-38 132.0 5.9 3.4e-38 131.2 4.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Epimerase PF01370.16 EDP41987.1 - 7.4e-25 87.7 0.0 1.4e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 EDP41987.1 - 3.4e-23 81.5 0.0 6.8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 PX domain NAD_binding_10 PF13460.1 EDP41987.1 - 2e-09 37.6 0.2 4.1e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDP41987.1 - 1.2e-07 30.9 0.3 1.4e-05 24.1 0.2 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EDP41987.1 - 1.3e-05 24.2 0.1 0.0028 16.6 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EDP41987.1 - 0.0017 17.1 0.0 0.003 16.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EDP41987.1 - 0.0054 16.6 0.1 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EDP41987.1 - 0.0084 15.3 0.1 0.023 13.9 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EDP41987.1 - 0.034 14.0 8.0 0.024 14.5 2.4 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EDP41987.1 - 0.1 12.4 0.4 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pou PF00157.12 EDP41987.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Vezatin PF12632.2 EDP41989.1 - 7.5e-06 25.2 0.0 1.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes 60KD_IMP PF02096.15 EDP41990.1 - 1.4e-39 135.8 5.2 2.2e-39 135.1 3.6 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein TBP PF00352.16 EDP41991.1 - 5.8e-62 205.0 0.2 1.7e-31 107.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EDP41991.1 - 4.3e-05 23.4 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) HSF_DNA-bind PF00447.12 EDP41992.1 - 4.1e-34 116.8 0.1 5.6e-34 116.4 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding RNA_pol_Rpc82 PF05645.8 EDP41994.1 - 2.9e-14 53.2 0.2 4.9e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EDP41994.1 - 5.6e-06 26.1 2.2 0.0067 16.2 0.4 3.6 3 1 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EDP41994.1 - 0.0019 17.6 0.0 0.0079 15.6 0.0 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit SNARE_assoc PF09335.6 EDP41995.1 - 6.6e-12 45.7 3.0 1.1e-11 44.9 2.1 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF2554 PF10829.3 EDP41995.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) Sld5 PF05916.6 EDP41996.1 - 2.1e-09 37.6 0.0 3.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein HrpJ PF07201.6 EDP41996.1 - 0.15 12.0 2.9 0.12 12.3 0.5 1.7 1 1 1 2 2 2 0 HrpJ-like domain RRM_1 PF00076.17 EDP41997.1 - 2.7e-37 126.2 0.0 8.5e-15 54.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP41997.1 - 2.5e-32 110.6 0.0 5.9e-13 48.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP41997.1 - 3.1e-21 74.9 0.0 7.1e-09 35.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP41997.1 - 0.0024 17.5 0.0 0.67 9.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif UPF0052 PF01933.13 EDP41998.1 - 3.4e-13 49.6 0.0 6.3e-13 48.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 tRNA_U5-meth_tr PF05958.6 EDP41999.1 - 2.4e-11 42.9 0.0 4.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EDP41999.1 - 1.8e-09 37.3 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EDP41999.1 - 3.3e-06 26.7 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EDP41999.1 - 9.7e-06 25.2 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EDP41999.1 - 3.4e-05 23.2 0.0 6.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EDP41999.1 - 9.1e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP41999.1 - 9.9e-05 22.8 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDP41999.1 - 0.00011 21.3 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EDP41999.1 - 0.00014 22.2 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDP41999.1 - 0.00078 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TPMT PF05724.6 EDP41999.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.13 EDP41999.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EDP41999.1 - 0.022 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EDP41999.1 - 0.027 14.0 0.0 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_32 PF13679.1 EDP41999.1 - 0.03 14.0 0.1 0.068 12.8 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EDP41999.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EDP41999.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EamA PF00892.15 EDP42000.1 - 7.3e-09 35.7 38.3 2.7e-08 33.9 4.6 3.2 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDP42000.1 - 0.0083 16.3 10.8 0.0083 16.3 7.5 3.7 3 2 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 EDP42000.1 - 0.078 12.6 23.9 0.069 12.8 4.6 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family RhoGAP PF00620.22 EDP42002.1 - 2e-38 131.4 0.1 6.8e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain RasGAP_C PF03836.10 EDP42002.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus KH_1 PF00013.24 EDP42003.1 - 1.8e-30 104.3 0.0 6e-09 35.4 0.0 5.5 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 EDP42003.1 - 2.4e-22 78.1 3.7 2.7e-07 30.0 0.1 5.3 5 0 0 5 5 5 4 KH domain Secretin_N PF03958.12 EDP42003.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.6 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain Macoilin PF09726.4 EDP42003.1 - 1.3 7.1 7.4 2.2 6.4 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RNA_pol_Rpb5_N PF03871.9 EDP42004.1 - 9e-30 102.9 2.5 1.3e-29 102.4 1.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EDP42004.1 - 2.6e-07 30.1 2.0 6.5e-07 28.8 1.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.7 EDP42004.1 - 3.7e-05 23.5 0.1 5.6e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Restriction endonuclease NAD_binding_1 PF00175.16 EDP42005.1 - 3.5e-28 98.3 0.0 5.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDP42005.1 - 5.7e-17 61.6 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDP42005.1 - 2.7e-06 27.3 0.0 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDP42005.1 - 0.00021 21.2 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain ABC_ATPase PF09818.4 EDP42006.1 - 4.9e-154 513.2 0.0 6.3e-154 512.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EDP42006.1 - 0.0019 17.6 0.0 0.0063 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDP42006.1 - 0.043 13.2 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Chitin_synth_2 PF03142.10 EDP42007.1 - 6.6e-224 744.1 0.1 8.9e-224 743.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDP42007.1 - 1.5e-18 67.2 6.9 2.1e-18 66.7 2.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDP42007.1 - 2.7e-15 56.7 0.1 1.7e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDP42007.1 - 0.00049 19.4 0.2 0.92 8.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDP42007.1 - 0.02 14.5 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.23 EDP42007.1 - 0.022 14.5 0.0 0.058 13.2 0.0 1.8 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DSPc PF00782.15 EDP42008.1 - 1.7e-05 24.3 0.2 6.3e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDP42008.1 - 0.00012 21.5 0.1 0.00033 20.0 0.1 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EDP42008.1 - 0.00028 20.3 0.1 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EDP42008.1 - 0.00057 19.9 0.1 0.0081 16.2 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF914 PF06027.7 EDP42009.1 - 2.9e-07 29.6 3.5 2.9e-07 29.6 2.4 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EDP42009.1 - 0.00041 20.3 7.4 0.00041 20.3 5.1 3.1 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.6 EDP42009.1 - 0.0031 16.4 1.1 0.0031 16.4 0.8 1.9 2 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EDP42009.1 - 0.018 15.2 6.5 0.018 15.2 4.5 3.1 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Bromodomain PF00439.20 EDP42010.1 - 1.6e-12 47.1 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain BAH PF01426.13 EDP42010.1 - 2e-12 46.9 0.0 3.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain Pkinase PF00069.20 EDP42011.1 - 4.5e-59 199.7 0.0 5.2e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42011.1 - 1.1e-19 70.5 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP42011.1 - 4.8e-07 29.7 0.0 4e-06 26.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDP42011.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EDP42011.1 - 0.017 14.1 0.1 0.034 13.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 EDP42011.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain YrbL-PhoP_reg PF10707.4 EDP42011.1 - 0.096 12.0 0.1 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL tRNA-synt_1b PF00579.20 EDP42012.1 - 1.6e-21 76.7 0.0 8.8e-21 74.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Vmethyltransf PF01660.12 EDP42012.1 - 0.0061 15.2 0.1 0.0081 14.8 0.0 1.2 1 0 0 1 1 1 1 Viral methyltransferase LSM PF01423.17 EDP42013.1 - 1.6e-12 46.7 0.0 2.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDP42013.1 - 1.5e-05 24.8 0.1 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Avl9 PF09794.4 EDP42014.1 - 3e-54 183.9 0.0 4.4e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EDP42014.1 - 0.0023 17.6 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Fibrillarin PF01269.12 EDP42016.1 - 2.9e-111 369.8 0.0 3.7e-111 369.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EDP42016.1 - 1.8e-05 24.3 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EDP42016.1 - 0.0036 16.8 0.1 0.0073 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EDP42016.1 - 0.0041 16.7 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Tubulin PF00091.20 EDP42017.1 - 1.1e-73 247.6 0.0 2.2e-73 246.6 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDP42017.1 - 9.9e-45 151.6 0.9 1.1e-44 151.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDP42017.1 - 1.8e-05 24.7 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4451 PF14616.1 EDP42017.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Ion_trans PF00520.26 EDP42018.1 - 2e-98 327.5 69.0 3.7e-39 134.0 3.3 6.0 5 1 1 6 6 6 4 Ion transport protein FlhC PF05280.6 EDP42018.1 - 0.044 13.2 0.0 0.61 9.5 0.0 2.6 3 0 0 3 3 3 0 Flagellar transcriptional activator (FlhC) BCS1_N PF08740.6 EDP42019.1 - 1.5e-51 174.7 0.0 1.9e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDP42019.1 - 5.5e-17 62.2 0.0 9.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDP42019.1 - 1.6e-05 25.7 0.0 3.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDP42019.1 - 0.00094 19.2 0.3 0.0036 17.3 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 EDP42019.1 - 0.0011 18.4 0.0 0.007 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP42019.1 - 0.0028 17.5 0.1 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDP42019.1 - 0.0037 16.9 0.3 0.027 14.1 0.0 2.5 2 1 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EDP42019.1 - 0.023 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDP42019.1 - 0.039 14.0 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDP42019.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EDP42019.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EDP42019.1 - 0.062 13.0 0.0 0.19 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EDP42019.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EDP42019.1 - 0.086 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EDP42019.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EDP42019.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 RNA helicase MgtE PF01769.11 EDP42020.1 - 2.6e-21 76.3 29.3 8.8e-08 32.5 0.2 4.8 5 0 0 5 5 5 3 Divalent cation transporter Ycf66_N PF07444.6 EDP42020.1 - 7.5 6.3 11.8 0.15 11.7 1.5 2.7 2 0 0 2 2 2 0 Ycf66 protein N-terminus PCI PF01399.22 EDP42021.1 - 6.4e-11 42.5 0.9 2.4e-10 40.6 0.1 2.5 2 0 0 2 2 2 1 PCI domain Peptidase_M15_2 PF05951.8 EDP42021.1 - 0.23 10.8 4.0 0.44 9.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF882) DUF382 PF04037.8 EDP42022.1 - 1.1e-57 193.3 0.0 1.9e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EDP42022.1 - 2.8e-19 68.2 6.0 2.8e-19 68.2 4.2 2.1 2 0 0 2 2 2 1 PSP Nop14 PF04147.7 EDP42022.1 - 0.26 9.1 7.4 0.46 8.3 5.1 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EDP42022.1 - 1.5 7.2 8.8 2.7 6.3 6.1 1.4 1 0 0 1 1 1 0 Daxx Family Proteasome PF00227.21 EDP42024.1 - 1.2e-49 168.1 0.0 1.5e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EDP42024.1 - 1.5e-12 46.5 0.1 3.1e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Rio2_N PF09202.6 EDP42024.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Pyr_redox_2 PF07992.9 EDP42025.1 - 7.8e-20 71.6 0.0 2.2e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EDP42025.1 - 1.8e-13 49.8 0.0 3.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EDP42025.1 - 1.6e-07 31.5 0.1 2.6e-06 27.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP42025.1 - 1.6e-05 25.0 0.0 8.6e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EDP42025.1 - 3e-05 24.2 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 EDP42025.1 - 3e-05 23.6 0.0 7.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FAD_binding_2 PF00890.19 EDP42025.1 - 0.018 13.9 1.4 0.45 9.2 0.0 2.2 1 1 1 2 2 2 0 FAD binding domain DUF498 PF04430.9 EDP42025.1 - 0.046 13.2 0.0 0.27 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) AIF_C PF14721.1 EDP42025.1 - 0.066 13.4 0.2 1.7 8.9 0.0 2.4 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EF-hand_4 PF12763.2 EDP42026.1 - 8.8e-37 125.0 0.0 4.1e-15 55.3 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EDP42026.1 - 2e-08 34.2 0.0 0.00054 20.0 0.0 4.3 4 1 1 5 5 5 1 EF-hand domain pair EF-hand_6 PF13405.1 EDP42026.1 - 8e-06 25.3 0.8 2.8 8.0 0.0 6.0 7 0 0 7 7 6 1 EF-hand domain EF-hand_1 PF00036.27 EDP42026.1 - 1.2e-05 24.2 0.1 0.31 10.4 0.0 4.4 6 0 0 6 6 4 1 EF hand Macoilin PF09726.4 EDP42026.1 - 0.0026 16.1 15.6 0.0035 15.6 10.8 1.1 1 0 0 1 1 1 1 Transmembrane protein EF-hand_8 PF13833.1 EDP42026.1 - 0.0033 17.0 0.0 1.1 8.9 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair ADIP PF11559.3 EDP42026.1 - 0.0068 16.3 7.5 0.0068 16.3 5.2 2.2 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF812 PF05667.6 EDP42026.1 - 0.025 13.1 14.0 0.038 12.5 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.1 EDP42026.1 - 0.087 12.2 19.9 0.13 11.6 13.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.14 EDP42026.1 - 0.089 10.6 16.5 0.056 11.2 9.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family End3 PF12761.2 EDP42026.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.7 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 IncA PF04156.9 EDP42026.1 - 0.3 10.6 30.3 0.018 14.6 16.7 1.8 1 1 1 2 2 2 0 IncA protein CALCOCO1 PF07888.6 EDP42026.1 - 0.52 8.5 20.7 0.82 7.8 14.3 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 EDP42026.1 - 0.81 9.4 23.6 1.5 8.5 16.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.4 EDP42026.1 - 0.87 9.5 21.5 0.014 15.4 2.3 3.3 2 1 1 3 3 3 0 Zinc finger-containing protein CENP-Q PF13094.1 EDP42026.1 - 1.2 9.0 32.3 0.29 11.1 11.2 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 EDP42026.1 - 1.6 7.3 17.3 2.6 6.6 12.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EDP42026.1 - 1.7 7.7 8.8 0.96 8.5 3.7 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EDP42026.1 - 2.3 6.6 17.8 7.7 4.8 12.4 1.5 1 1 0 1 1 1 0 AAA domain EzrA PF06160.7 EDP42026.1 - 2.6 6.1 19.4 3.6 5.6 13.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ERM PF00769.14 EDP42026.1 - 3.9 6.9 31.8 0.76 9.2 19.4 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1515 PF07439.6 EDP42026.1 - 6.3 6.6 6.4 6.7 6.5 3.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) APG6 PF04111.7 EDP42026.1 - 9.3 5.1 24.0 2.3 7.2 13.6 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 UBA PF00627.26 EDP42027.1 - 2e-06 27.4 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.5 EDP42027.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CUE PF02845.11 EDP42027.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 CUE domain SAGA-Tad1 PF12767.2 EDP42028.1 - 7e-48 163.4 0.4 1.2e-47 162.7 0.3 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Ependymin PF00811.13 EDP42028.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Ependymin Pkinase PF00069.20 EDP42029.1 - 1e-55 188.7 0.0 1.4e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42029.1 - 3.6e-38 131.1 0.0 5.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42029.1 - 1.1e-08 34.4 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42029.1 - 0.0099 15.6 4.2 0.07 12.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP42029.1 - 0.062 12.3 0.1 0.24 10.4 0.0 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.23 EDP42030.1 - 8.7e-16 58.1 0.8 1.5e-15 57.3 0.2 1.7 2 0 0 2 2 2 1 SPRY domain bZIP_1 PF00170.16 EDP42031.1 - 4.2e-07 29.8 8.3 1.8e-06 27.7 3.3 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDP42031.1 - 0.39 10.5 9.8 0.33 10.8 4.2 2.2 1 1 1 2 2 2 0 Basic region leucine zipper KTI12 PF08433.5 EDP42032.1 - 2.4e-45 154.8 0.0 2.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDP42032.1 - 6.4e-10 39.0 0.1 8.3e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP42032.1 - 0.086 13.6 0.0 0.14 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Hairpins PF04877.7 EDP42033.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 HrpZ DEAD PF00270.24 EDP42034.1 - 3.3e-43 147.0 0.0 1e-42 145.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42034.1 - 4.4e-23 80.9 0.0 1.3e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PAP_assoc PF03828.14 EDP42035.1 - 2e-16 59.6 0.1 2.3e-15 56.2 0.0 2.7 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDP42035.1 - 1.2e-08 35.1 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Gloverin PF10793.4 EDP42035.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Gloverin-like protein AAA PF00004.24 EDP42036.1 - 1.4e-33 115.9 0.0 1.9e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP42036.1 - 5.2e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDP42036.1 - 5.7e-08 33.6 0.2 7e-07 30.0 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDP42036.1 - 1e-07 32.1 0.0 2.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP42036.1 - 1.5e-06 27.9 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDP42036.1 - 2.9e-06 27.5 0.0 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDP42036.1 - 6.5e-06 26.1 0.0 1.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EDP42036.1 - 9.7e-06 25.2 0.1 8.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EDP42036.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDP42036.1 - 3e-05 23.9 0.0 6.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDP42036.1 - 5.1e-05 22.7 0.2 0.024 14.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.1 EDP42036.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDP42036.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EDP42036.1 - 0.00021 20.7 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EDP42036.1 - 0.00041 20.0 0.1 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EDP42036.1 - 0.0005 19.0 0.1 0.0061 15.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EDP42036.1 - 0.00052 19.6 0.0 0.00095 18.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EDP42036.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP42036.1 - 0.00093 18.3 0.1 0.0037 16.3 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EDP42036.1 - 0.0012 19.0 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EDP42036.1 - 0.0015 18.3 0.3 0.09 12.4 0.2 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 EDP42036.1 - 0.0019 18.1 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDP42036.1 - 0.0049 15.9 0.0 0.011 14.8 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 EDP42036.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 EDP42036.1 - 0.013 15.0 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDP42036.1 - 0.017 14.3 0.0 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EDP42036.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 EDP42036.1 - 0.017 14.1 0.0 2.8 6.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.4 EDP42036.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EDP42036.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EDP42036.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 EDP42036.1 - 0.026 14.1 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDP42036.1 - 0.034 12.8 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EDP42036.1 - 0.036 14.3 0.0 0.061 13.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 EDP42036.1 - 0.053 13.1 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EDP42036.1 - 0.054 13.8 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EDP42036.1 - 0.057 13.3 0.2 0.25 11.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain FMN_red PF03358.10 EDP42036.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase PduV-EutP PF10662.4 EDP42036.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Phosphodiest PF01663.17 EDP42036.1 - 0.068 12.4 1.0 0.19 10.9 0.2 1.8 1 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase FtsK_SpoIIIE PF01580.13 EDP42036.1 - 0.078 12.4 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EDP42036.1 - 0.088 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KaiC PF06745.8 EDP42036.1 - 0.11 11.5 0.0 0.53 9.3 0.0 1.9 1 1 1 2 2 2 0 KaiC MMR_HSR1 PF01926.18 EDP42036.1 - 0.12 12.2 0.1 0.77 9.7 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EDP42036.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 EDP42036.1 - 0.21 10.0 0.0 0.27 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EDP42037.1 - 9.2e-13 47.5 0.2 2.3e-05 24.1 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat PP2C PF00481.16 EDP42038.1 - 1.1e-56 192.0 0.0 1.8e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C HlyIII PF03006.15 EDP42039.1 - 8.6e-49 165.9 21.2 1.2e-48 165.5 14.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF1129 PF06570.6 EDP42039.1 - 2.5 7.3 5.4 4.3 6.5 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) TAF8_C PF10406.4 EDP42040.1 - 3.9e-07 30.0 0.0 9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term E1-E2_ATPase PF00122.15 EDP42041.1 - 1.4e-54 184.5 1.1 3.8e-54 183.1 0.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDP42041.1 - 3.1e-33 114.8 5.6 3.1e-33 114.8 3.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDP42041.1 - 4e-28 99.2 0.0 1.6e-26 94.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDP42041.1 - 5.8e-17 60.9 0.0 5.8e-17 60.9 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDP42041.1 - 6.5e-16 58.0 0.0 1.5e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDP42041.1 - 2.1e-12 47.6 0.0 6e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDP42041.1 - 0.0002 21.0 0.2 0.0046 16.5 0.3 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EDP42041.1 - 0.043 13.3 1.8 0.11 12.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) DUF2207 PF09972.4 EDP42041.1 - 0.062 11.8 3.4 0.099 11.2 0.1 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Rdx PF10262.4 EDP42043.1 - 4e-18 65.1 0.0 7.3e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Rdx family DUF2613 PF11021.3 EDP42043.1 - 0.039 13.6 5.7 0.18 11.5 3.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) SIR2 PF02146.12 EDP42045.1 - 3.2e-26 92.1 0.1 4.2e-18 65.6 0.0 3.3 3 0 0 3 3 3 2 Sir2 family ETF PF01012.16 EDP42046.1 - 5.7e-40 136.7 1.6 1e-39 135.8 1.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EDP42046.1 - 2.2e-35 120.1 1.6 4.5e-35 119.1 0.1 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Apc4 PF12896.2 EDP42047.1 - 1.7e-39 135.3 0.1 2.6e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Ku PF02735.11 EDP42048.1 - 3.5e-19 69.0 0.0 5.8e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EDP42048.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like Glyco_trans_1_4 PF13692.1 EDP42049.1 - 4.7e-16 59.1 0.1 1.4e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EDP42049.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDP42049.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ufd2P_core PF10408.4 EDP42050.1 - 1.5e-175 585.0 0.0 1.8e-175 584.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EDP42050.1 - 3.5e-25 87.7 0.2 1.2e-24 86.0 0.1 2.0 1 0 0 1 1 1 1 U-box domain DivIC PF04977.10 EDP42050.1 - 0.06 12.8 0.2 0.26 10.7 0.2 2.1 1 0 0 1 1 1 0 Septum formation initiator EIF_2_alpha PF07541.7 EDP42051.1 - 2.5e-42 143.2 0.5 9.4e-42 141.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EDP42051.1 - 1.7e-12 47.2 1.5 2.2e-12 46.8 0.1 1.9 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 EDP42051.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF4453 PF14627.1 EDP42051.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Cpn60_TCP1 PF00118.19 EDP42052.1 - 6.9e-142 473.4 0.5 8e-142 473.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 EDP42052.1 - 0.0097 15.7 0.1 0.3 10.9 0.1 2.7 2 0 0 2 2 2 1 Resolvase, N terminal domain Pro_isomerase PF00160.16 EDP42053.1 - 3.3e-47 160.5 0.0 6.6e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EDP42053.1 - 2.7e-11 42.8 1.1 0.0098 15.7 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat AviRa PF11599.3 EDP42053.1 - 0.022 13.8 0.0 0.71 8.8 0.0 2.4 3 0 0 3 3 3 0 RRNA methyltransferase AviRa Neural_ProG_Cyt PF06567.6 EDP42054.1 - 0.075 13.1 0.1 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain BCNT PF07572.7 EDP42055.1 - 1.3e-16 60.2 1.8 2.2e-16 59.5 1.2 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development FliJ PF02050.11 EDP42055.1 - 0.028 14.4 0.1 0.065 13.2 0.1 1.6 1 1 1 2 2 2 0 Flagellar FliJ protein zf-RING_2 PF13639.1 EDP42057.1 - 0.24 11.2 4.6 0.52 10.1 1.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EDP42057.1 - 0.37 10.5 4.6 2.4 7.9 2.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Na_Ca_ex PF01699.19 EDP42058.1 - 4.3e-24 84.7 41.8 8.5e-15 54.5 6.8 3.9 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EDP42058.1 - 9.6e-09 35.5 13.0 9.6e-09 35.5 9.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Semialdhyde_dhC PF02774.13 EDP42059.1 - 3.4e-39 134.5 0.0 4.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EDP42059.1 - 6.8e-27 94.1 0.0 2e-26 92.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EDP42059.1 - 0.0064 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ILVD_EDD PF00920.16 EDP42060.1 - 1e-196 654.3 0.1 1.2e-196 654.2 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family MR_MLE_C PF13378.1 EDP42060.1 - 0.023 14.6 0.3 22 5.0 0.0 3.4 2 1 1 3 3 3 0 Enolase C-terminal domain-like PS_Dcarbxylase PF02666.10 EDP42061.1 - 1.4e-49 168.1 0.0 2e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EDP42061.1 - 7.6e-16 57.7 0.0 8.2e-15 54.4 0.1 2.5 3 0 0 3 3 3 1 C2 domain EF-hand_1 PF00036.27 EDP42061.1 - 0.00017 20.6 0.1 0.00045 19.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDP42061.1 - 0.00044 20.3 0.5 0.0044 17.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EDP42061.1 - 0.002 17.8 0.1 0.0063 16.3 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EDP42061.1 - 0.011 14.9 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 EF hand Kinocilin PF15033.1 EDP42061.1 - 0.14 11.7 1.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinocilin protein Cytochrom_C PF00034.16 EDP42062.1 - 1.1e-09 38.9 0.1 2.1e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDP42062.1 - 8.8e-09 35.3 2.2 1.6e-07 31.3 1.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EDP42062.1 - 0.00081 18.8 0.3 0.007 15.8 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EDP42062.1 - 0.049 13.9 0.1 0.079 13.2 0.1 1.3 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase GATA PF00320.22 EDP42063.1 - 1.5e-14 53.0 2.5 2.8e-14 52.1 1.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_L15e PF00827.12 EDP42064.1 - 9e-92 305.8 10.3 1.1e-91 305.6 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L18_c PF14204.1 EDP42065.1 - 2.4e-35 120.9 6.3 2.9e-35 120.6 4.4 1.1 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EDP42065.1 - 0.00078 19.4 0.2 0.6 10.1 0.0 2.8 2 1 0 2 2 2 2 Threonine synthase N terminus DUF3340 PF11818.3 EDP42065.1 - 0.0028 17.6 2.3 0.0039 17.1 0.9 1.6 1 1 1 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) MtrA PF04208.9 EDP42065.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Staphylokinase PF02821.11 EDP42065.1 - 0.031 14.0 2.7 0.7 9.6 0.4 2.2 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family K_oxygenase PF13434.1 EDP42065.1 - 0.09 11.6 0.8 0.11 11.4 0.6 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) His_Phos_2 PF00328.17 EDP42066.1 - 1.5e-38 133.0 1.6 1.9e-38 132.7 1.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_2 PF00328.17 EDP42067.1 - 3.8e-44 151.4 0.0 4.8e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) B12D PF06522.6 EDP42068.1 - 5e-12 45.3 0.0 5.3e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ERG4_ERG24 PF01222.12 EDP42069.1 - 3.3e-144 480.6 8.6 3.7e-144 480.4 6.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EDP42069.1 - 1.9e-06 27.3 1.0 4.1e-06 26.2 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EDP42069.1 - 2.8e-05 24.1 1.0 0.00014 21.9 0.0 2.8 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EDP42069.1 - 0.022 14.9 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NAD_binding_8 PF13450.1 EDP42070.1 - 6.9e-10 38.8 0.1 0.00027 20.8 0.1 2.3 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDP42070.1 - 0.00032 19.8 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EDP42070.1 - 0.00073 18.5 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDP42070.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDP42070.1 - 0.035 13.1 0.1 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EDP42070.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDP42070.1 - 0.16 12.4 0.2 0.61 10.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDP42070.1 - 0.19 10.5 0.1 0.25 10.1 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Prenylcys_lyase PF07156.9 EDP42071.1 - 4.2e-11 42.3 0.0 5e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Cofilin_ADF PF00241.15 EDP42072.1 - 2.9e-44 149.9 0.7 3.3e-44 149.8 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.17 EDP42073.1 - 1.5e-56 190.2 0.0 1.8e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP42073.1 - 1.3e-15 57.9 0.0 1.8e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP42073.1 - 5.8e-07 28.9 0.0 9.8e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDP42073.1 - 0.00073 18.7 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDP42073.1 - 0.026 13.6 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GDA1_CD39 PF01150.12 EDP42074.1 - 3.1e-89 299.4 0.0 3.9e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EDP42074.1 - 0.028 13.6 0.1 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Ppx/GppA phosphatase family DcpS_C PF11969.3 EDP42075.1 - 1.5e-25 89.6 0.2 5.9e-25 87.7 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EDP42075.1 - 3e-18 66.2 0.0 4.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal TFCD_C PF12612.3 EDP42076.1 - 1.3e-17 63.8 0.4 2.3e-16 59.8 0.0 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal B56 PF01603.15 EDP42076.1 - 0.007 15.0 0.0 1.2 7.7 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd3 PF12719.2 EDP42076.1 - 0.024 13.6 3.4 0.056 12.4 0.9 2.7 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Vac14_Fab1_bd PF12755.2 EDP42076.1 - 0.026 14.8 0.0 0.2 12.0 0.0 2.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region FANCI_S2 PF14676.1 EDP42076.1 - 0.1 12.4 4.0 0.23 11.3 0.7 2.8 2 1 0 2 2 2 0 FANCI solenoid 2 Racemase_4 PF13615.1 EDP42076.1 - 0.11 12.8 1.7 1.1 9.5 0.8 2.9 3 0 0 3 3 3 0 Putative alanine racemase HEAT PF02985.17 EDP42076.1 - 0.2 11.8 0.1 0.2 11.8 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat HEAT_PBS PF03130.11 EDP42076.1 - 0.38 11.3 12.1 1 10.0 0.7 5.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Hpt PF01627.18 EDP42077.1 - 4.1e-10 39.5 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Hpt domain DUF4132 PF13569.1 EDP42077.1 - 0.024 14.1 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4132) DUF544 PF04424.8 EDP42078.1 - 2.4e-15 56.3 0.0 3.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Peptidase_M24 PF00557.19 EDP42079.1 - 3.6e-26 92.0 0.2 5.1e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3588 PF12140.3 EDP42079.1 - 0.07 13.2 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) Pkinase PF00069.20 EDP42080.1 - 1.5e-39 135.7 0.0 3.1e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42080.1 - 6.6e-12 45.0 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP42080.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 3.5 4 1 0 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDP42080.1 - 0.0025 17.3 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinetochor_Ybp2 PF08568.5 EDP42080.1 - 0.053 11.7 0.0 0.34 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin Pox_ser-thr_kin PF05445.6 EDP42080.1 - 0.75 8.5 0.0 1.2 7.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_2 PF07724.9 EDP42081.1 - 3.9e-46 157.0 0.0 2.7e-42 144.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EDP42081.1 - 1.8e-26 91.8 1.4 4e-26 90.7 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EDP42081.1 - 8.8e-20 71.2 0.0 2.7e-10 40.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP42081.1 - 1.3e-12 47.5 0.2 2e-07 30.8 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDP42081.1 - 6.1e-09 35.5 0.1 7.6e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EDP42081.1 - 1.5e-08 34.8 0.5 0.012 15.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EDP42081.1 - 9.5e-08 32.2 8.9 0.00047 20.1 0.0 5.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EDP42081.1 - 1.6e-06 28.0 0.0 0.016 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDP42081.1 - 8.7e-05 22.0 0.4 0.04 13.3 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.1 EDP42081.1 - 0.00056 20.7 1.7 0.52 11.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EDP42081.1 - 0.00062 20.0 0.5 0.8 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EDP42081.1 - 0.00072 19.7 0.1 0.49 10.5 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 EDP42081.1 - 0.00092 18.9 5.3 0.028 14.1 0.1 3.3 3 1 0 3 3 2 1 Archaeal ATPase SRP54 PF00448.17 EDP42081.1 - 0.0012 18.3 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EDP42081.1 - 0.0018 17.4 1.1 2.9 6.9 0.0 3.5 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EDP42081.1 - 0.002 18.1 2.0 2.2 8.2 0.0 4.3 4 1 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EDP42081.1 - 0.0027 17.4 0.0 0.6 9.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EDP42081.1 - 0.0046 16.6 0.1 0.23 11.1 0.0 2.7 3 0 0 3 3 2 1 NACHT domain IncA PF04156.9 EDP42081.1 - 0.0046 16.5 10.7 0.011 15.3 7.4 1.6 1 0 0 1 1 1 1 IncA protein TrwB_AAD_bind PF10412.4 EDP42081.1 - 0.019 13.6 0.2 5.6 5.4 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EDP42081.1 - 0.026 14.2 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EDP42081.1 - 0.036 13.6 0.1 0.48 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EDP42081.1 - 0.046 13.3 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EDP42081.1 - 0.048 13.2 1.7 0.45 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EDP42081.1 - 0.053 12.7 0.0 0.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDP42081.1 - 0.14 12.5 5.5 57 3.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EDP42081.1 - 0.15 11.5 0.3 8.3 5.8 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EDP42081.1 - 0.18 12.0 3.1 27 5.0 0.0 3.5 2 1 1 3 3 3 0 ABC transporter Atg14 PF10186.4 EDP42081.1 - 0.96 8.3 7.3 1.6 7.6 5.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BCIP PF13862.1 EDP42082.1 - 1.3e-19 70.4 0.0 1.8e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein NIF PF03031.13 EDP42083.1 - 3.2e-52 176.3 0.1 4.7e-52 175.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF663 PF04950.7 EDP42085.1 - 1.9e-90 302.8 0.0 1.9e-90 302.8 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDP42085.1 - 3.5e-30 103.3 0.0 2.6e-29 100.5 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.1 EDP42085.1 - 2.3e-05 24.5 0.0 7.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDP42085.1 - 5.5e-05 22.9 0.1 0.00014 21.5 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EDP42085.1 - 9.8e-05 21.8 3.5 0.0012 18.3 0.0 3.0 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EDP42085.1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EDP42085.1 - 0.0021 17.8 0.0 0.0067 16.1 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EDP42085.1 - 0.0024 17.7 0.0 0.0084 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDP42085.1 - 0.0032 17.4 0.5 0.016 15.2 0.2 2.4 2 1 0 2 2 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EDP42085.1 - 0.0037 17.5 0.0 0.0037 17.5 0.0 2.9 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.7 EDP42085.1 - 0.004 16.8 0.0 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EDP42085.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDP42085.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EDP42085.1 - 0.0078 17.0 0.0 0.0078 17.0 0.0 3.3 2 1 1 3 3 3 1 AAA domain Miro PF08477.8 EDP42085.1 - 0.013 16.0 1.6 0.028 14.9 0.0 2.5 2 0 0 2 2 1 0 Miro-like protein PduV-EutP PF10662.4 EDP42085.1 - 0.018 14.5 0.1 0.051 13.0 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EDP42085.1 - 0.019 14.4 0.0 0.069 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDP42085.1 - 0.031 14.1 2.5 0.11 12.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDP42085.1 - 0.037 13.4 0.1 0.083 12.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EDP42085.1 - 0.043 13.5 0.5 0.09 12.4 0.3 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EDP42085.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDP42085.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.1 EDP42085.1 - 9.4 6.5 10.4 0.88 9.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain ADH_zinc_N PF00107.21 EDP42086.1 - 3.8e-11 42.6 0.0 5.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AA_permease PF00324.16 EDP42087.1 - 2.9e-122 408.4 44.4 3.4e-122 408.2 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDP42087.1 - 1.6e-31 109.3 47.5 2.1e-31 108.9 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_2 PF07992.9 EDP42088.1 - 1.3e-17 64.3 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDP42088.1 - 1.6e-11 44.4 0.0 5.2e-08 33.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.1 EDP42088.1 - 2e-07 30.2 0.2 0.00093 18.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EDP42088.1 - 3.4e-07 30.3 0.1 8.4e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EDP42088.1 - 3.9e-07 28.9 0.4 7.3e-05 21.7 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EDP42088.1 - 7.7e-06 25.0 0.8 4.9e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 EF hand NAD_binding_9 PF13454.1 EDP42088.1 - 0.014 15.1 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding EF-hand_8 PF13833.1 EDP42088.1 - 0.025 14.1 0.1 0.083 12.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair NAD_binding_7 PF13241.1 EDP42088.1 - 0.081 13.1 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EDP42088.1 - 0.11 12.5 0.0 27 4.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Transglut_C PF00927.17 EDP42088.1 - 0.15 12.1 0.2 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Asp_Glu_race PF01177.17 EDP42088.1 - 0.17 11.7 0.0 0.8 9.5 0.0 1.9 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase Syja_N PF02383.13 EDP42089.1 - 6.6e-65 218.9 0.0 1.1e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EDP42089.1 - 1.9e-22 80.3 0.0 4.3e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_13 PF13166.1 EDP42090.1 - 0.16 10.4 56.1 0.093 11.1 1.4 4.2 2 1 2 4 4 4 0 AAA domain Sec34 PF04136.10 EDP42090.1 - 2 8.1 21.9 0.41 10.3 1.2 4.5 4 0 0 4 4 4 0 Sec34-like family DUF812 PF05667.6 EDP42090.1 - 3.2 6.1 80.5 0.055 11.9 15.5 4.7 1 1 2 4 4 4 0 Protein of unknown function (DUF812) PHD PF00628.24 EDP42091.1 - 1.5e-08 34.2 9.2 2.5e-08 33.4 6.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EDP42091.1 - 0.0039 16.8 1.4 0.0073 15.9 1.0 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger PHD_2 PF13831.1 EDP42091.1 - 0.02 14.1 6.8 0.036 13.3 4.7 1.4 1 0 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 EDP42091.1 - 0.034 14.0 1.5 0.053 13.4 1.1 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Peptidase_M16 PF00675.15 EDP42092.1 - 1.1e-39 135.5 0.0 1.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDP42092.1 - 2.9e-38 131.3 0.0 4.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Abhydrolase_6 PF12697.2 EDP42093.1 - 7.2e-22 78.3 0.2 1.7e-21 77.1 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42093.1 - 8.1e-15 54.8 0.0 2.8e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDP42093.1 - 9.5e-05 22.1 0.5 0.0002 21.1 0.4 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EDP42093.1 - 0.0029 17.0 0.0 2.4 7.4 0.0 2.5 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EDP42093.1 - 0.003 17.1 0.1 0.17 11.4 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EDP42093.1 - 0.016 14.5 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EDP42093.1 - 0.027 13.6 0.0 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Linker_histone PF00538.14 EDP42094.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Pkinase PF00069.20 EDP42095.1 - 5.4e-08 32.2 0.0 9.1e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDP42095.1 - 2.3e-06 27.5 0.1 5.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP42095.1 - 0.017 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EDP42095.1 - 0.027 13.2 0.1 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EDP42095.1 - 0.069 12.7 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase IPK PF03770.11 EDP42097.1 - 9.2e-42 142.9 0.0 1.7e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_L14e PF01929.12 EDP42098.1 - 2.3e-21 75.9 2.6 5.7e-19 68.2 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L14 Ribosomal_S8 PF00410.14 EDP42099.1 - 1.4e-24 86.3 0.0 1.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 EDP42100.1 - 3.5e-21 75.2 0.0 4.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EDP42100.1 - 0.11 13.1 0.1 0.12 13.0 0.1 1.2 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Glyco_hydro_8 PF01270.12 EDP42101.1 - 1.8e-40 138.7 0.0 2.2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DNA_pol_A_exo1 PF01612.15 EDP42102.1 - 1.6e-19 70.0 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF508 PF04370.7 EDP42102.1 - 0.0084 15.7 3.7 0.39 10.3 1.7 3.0 2 1 0 3 3 3 1 Domain of unknown function (DUF508) DnaJ PF00226.26 EDP42103.1 - 2.4e-16 59.2 0.2 2.4e-16 59.2 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain tRNA-synt_2b PF00587.20 EDP42104.1 - 1.7e-34 118.9 0.3 2.8e-34 118.1 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDP42104.1 - 7.3e-13 48.4 9.8 1.1e-11 44.7 4.9 2.6 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain ProRS-C_1 PF09180.6 EDP42105.1 - 1.7e-25 88.7 0.2 3.3e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EDP42105.1 - 1.6e-24 86.3 0.0 2.5e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP42105.1 - 4e-17 61.9 0.0 4.6e-16 58.5 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain tRNA_edit PF04073.10 EDP42105.1 - 9.7e-13 48.0 0.2 2.1e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain SRP19 PF01922.12 EDP42106.1 - 2.5e-16 60.0 0.0 4.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein DUF3617 PF12276.3 EDP42106.1 - 1.1 8.7 5.3 1.9 7.9 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) zf-CCHC PF00098.18 EDP42107.1 - 7.8e-51 167.6 52.3 7.6e-08 31.9 1.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EDP42107.1 - 2.8e-15 55.6 39.7 0.011 15.3 0.3 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EDP42107.1 - 3.2e-10 39.5 36.2 0.054 13.2 0.2 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EDP42107.1 - 0.00018 20.8 37.9 1.6 8.3 0.2 7.2 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 EDP42107.1 - 0.0098 15.5 1.2 0.0098 15.5 0.8 6.8 6 1 1 7 7 7 4 Zinc knuckle IBR PF01485.16 EDP42107.1 - 0.12 12.3 0.8 0.12 12.3 0.5 5.8 3 2 2 5 5 5 0 IBR domain SKN1 PF03935.10 EDP42108.1 - 4.3e-170 566.1 3.1 6.7e-170 565.5 2.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DEAD PF00270.24 EDP42109.1 - 1.1e-18 67.3 0.0 2.4e-17 62.9 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42109.1 - 3.9e-05 23.4 0.0 8.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP42109.1 - 0.027 14.2 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDP42109.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Fer2 PF00111.22 EDP42110.1 - 7.1e-11 41.7 0.7 1.1e-10 41.1 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Sugar_tr PF00083.19 EDP42111.1 - 9.6e-53 179.3 15.1 1.3e-52 178.9 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP42111.1 - 0.00019 20.2 31.6 0.017 13.8 3.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EDP42112.1 - 5.7e-23 79.9 12.3 2.9e-06 26.9 0.1 6.7 6 1 1 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EDP42112.1 - 3.3e-05 23.6 0.0 0.0001 22.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDP42112.1 - 5.3e-05 21.2 0.3 0.0034 15.2 0.2 2.4 2 0 0 2 2 2 2 IKI3 family TFIIIC_delta PF12657.2 EDP42112.1 - 0.00029 20.6 0.9 0.47 10.1 0.2 3.0 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Nbas_N PF15492.1 EDP42112.1 - 0.037 13.1 0.3 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.20 EDP42113.1 - 8.3e-60 202.1 0.0 9.7e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42113.1 - 2.6e-26 92.2 0.0 3.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42113.1 - 0.002 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42113.1 - 0.03 14.0 0.1 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDP42113.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Utp12 PF04003.7 EDP42114.1 - 4.3e-11 42.6 0.1 7.7e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EDP42114.1 - 0.012 15.4 0.0 0.29 11.0 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat ATP12 PF07542.6 EDP42115.1 - 0.055 13.4 0.3 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 ATP12 chaperone protein Cut8_C PF08559.5 EDP42116.1 - 9.2e-05 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle PRELI PF04707.9 EDP42117.1 - 2.7e-17 62.7 0.0 3.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family IP_trans PF02121.13 EDP42117.1 - 0.078 12.1 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Suf PF05843.9 EDP42118.1 - 1.2e-68 231.8 0.4 1.7e-67 228.0 0.0 3.0 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EDP42118.1 - 0.00021 21.5 0.6 0.64 10.4 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42118.1 - 0.091 13.4 10.6 9.1 7.2 0.0 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDP42119.1 - 3.7e-50 167.4 22.7 3.3e-16 58.6 0.0 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EDP42119.1 - 1.3e-43 144.8 18.1 1.6e-05 24.3 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42119.1 - 4.6e-39 129.2 17.6 0.00094 18.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42119.1 - 2.7e-24 84.9 15.4 1.1e-10 41.3 0.0 6.4 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDP42119.1 - 9.8e-21 71.9 14.9 0.039 13.7 0.0 9.3 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDP42119.1 - 1.2e-19 70.4 9.3 4.8e-05 23.9 0.0 6.5 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42119.1 - 8.8e-19 66.3 5.0 0.0017 18.8 0.0 8.9 5 3 5 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDP42119.1 - 1.8e-15 57.0 8.8 0.00048 20.4 0.0 6.7 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDP42119.1 - 1.2e-12 46.5 5.4 0.28 11.0 0.0 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDP42119.1 - 1e-09 37.8 8.9 0.21 11.8 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDP42119.1 - 2e-08 33.9 1.4 0.22 11.3 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EDP42119.1 - 0.00095 19.2 14.0 0.14 12.2 0.5 4.4 3 3 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDP42119.1 - 0.0015 18.4 5.8 0.61 10.0 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.3 EDP42119.1 - 0.0089 14.8 16.1 0.02 13.6 0.2 3.8 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EDP42119.1 - 0.028 14.8 15.8 30 5.3 0.3 7.9 10 0 0 10 10 9 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.3 EDP42120.1 - 5.3e-23 82.1 26.0 1.7e-22 80.5 18.0 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Zn_clus PF00172.13 EDP42121.1 - 1.5e-05 24.7 8.5 3.3e-05 23.6 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3414 PF11894.3 EDP42122.1 - 1.1e-226 755.2 0.0 1.5e-226 754.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Pyridoxal_deC PF00282.14 EDP42123.1 - 2.3e-99 332.3 0.0 2.7e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF2269 PF10027.4 EDP42125.1 - 0.048 13.4 5.7 0.031 14.0 2.6 1.6 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Thioredoxin PF00085.15 EDP42127.1 - 3.8e-05 23.3 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TruB_N PF01509.13 EDP42129.1 - 2.1e-38 131.8 0.0 1.5e-36 125.8 0.0 2.1 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) Formyl_trans_N PF00551.14 EDP42130.1 - 2.7e-18 66.1 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EDP42130.1 - 2.6e-07 30.6 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF500 PF04366.7 EDP42131.1 - 1.6e-36 124.5 0.0 2.8e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Esterase PF00756.15 EDP42132.1 - 7.7e-43 146.7 0.0 9.5e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EDP42132.1 - 1.3e-06 28.1 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDP42132.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EDP42132.1 - 0.004 16.0 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EDP42132.1 - 0.0053 16.6 0.0 0.0073 16.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP42132.1 - 0.017 14.7 0.1 0.047 13.2 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDP42132.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EDP42132.1 - 0.032 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EDP42132.1 - 0.035 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DnaJ PF00226.26 EDP42133.1 - 0.008 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Abi PF02517.11 EDP42134.1 - 1.8e-16 60.0 0.8 4e-16 58.9 0.6 1.5 1 0 0 1 1 1 1 CAAX protease self-immunity DUF883 PF05957.8 EDP42135.1 - 0.00011 22.5 2.9 0.0048 17.2 0.1 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EDP42135.1 - 0.0035 17.6 2.6 0.33 11.3 1.8 2.1 1 1 0 1 1 1 1 YtxH-like protein Apolipoprotein PF01442.13 EDP42135.1 - 0.025 14.0 3.2 0.058 12.8 0.3 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Chlorosome_CsmC PF11098.3 EDP42135.1 - 0.11 12.2 1.1 0.24 11.1 0.1 1.8 1 1 1 2 2 2 0 Chlorosome envelope protein C GvpO PF05800.6 EDP42135.1 - 0.13 12.2 1.0 1.1 9.2 0.0 2.0 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO Tape_meas_lam_C PF09718.5 EDP42135.1 - 0.22 11.4 8.0 0.33 10.8 0.7 2.5 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DivIVA PF05103.8 EDP42135.1 - 0.32 11.0 5.4 4 7.4 3.7 2.0 1 1 0 1 1 1 0 DivIVA protein CsbD PF05532.7 EDP42135.1 - 0.5 10.0 13.0 1 9.0 0.8 3.3 2 1 1 3 3 3 0 CsbD-like ATP-synt_B PF00430.13 EDP42135.1 - 0.96 9.2 8.3 7.9 6.2 5.8 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HrpE PF06188.7 EDP42135.1 - 1 9.1 7.1 5.3 6.7 4.8 1.8 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E MT0933_antitox PF14013.1 EDP42135.1 - 4.9 7.3 10.2 7.3e+02 0.3 7.1 3.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein Inositol_P PF00459.20 EDP42136.1 - 4.3e-47 160.6 0.2 2e-46 158.5 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family AAA_5 PF07728.9 EDP42137.1 - 1.1e-67 226.0 0.0 1.7e-28 99.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 EDP42137.1 - 0.00035 20.7 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 EDP42137.1 - 0.00078 19.0 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDP42137.1 - 0.054 13.4 0.1 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDP42137.1 - 0.077 13.1 0.1 1.9 8.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EDP42137.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CdhC PF03598.10 EDP42137.1 - 0.11 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Raptor_N PF14538.1 EDP42138.1 - 6.3e-62 207.9 1.9 6.7e-62 207.8 0.0 2.1 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EDP42138.1 - 1.5e-10 40.5 6.5 0.12 12.3 0.0 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.17 EDP42138.1 - 4.3e-07 29.4 12.3 0.01 15.8 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EDP42138.1 - 0.00015 22.1 6.8 0.31 11.5 0.1 5.6 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EDP42138.1 - 0.024 14.9 0.3 0.024 14.9 0.2 4.4 3 1 2 5 5 5 0 HEAT repeats BBS2_Mid PF14783.1 EDP42138.1 - 0.13 12.0 0.0 2.1 8.1 0.0 2.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cnd1 PF12717.2 EDP42138.1 - 0.17 11.7 0.6 6.9 6.4 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 EDP42138.1 - 0.3 10.8 0.1 0.63 9.8 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain RIX1 PF08167.7 EDP42139.1 - 0.22 11.2 8.9 1.1 8.9 0.1 4.6 4 1 0 5 5 5 0 rRNA processing/ribosome biogenesis zf-CCCH_2 PF14608.1 EDP42140.1 - 3.1e-06 26.9 7.9 3.1e-06 26.9 5.5 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Ank_2 PF12796.2 EDP42140.1 - 5e-05 23.5 0.0 9.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP42140.1 - 0.00021 21.7 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH PF00642.19 EDP42140.1 - 0.001 18.6 12.4 0.13 11.9 1.8 2.6 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.1 EDP42140.1 - 0.0013 18.9 0.0 0.036 14.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EDP42140.1 - 0.048 13.4 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 EDP42140.1 - 0.092 13.0 0.0 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.20 EDP42141.1 - 5.7e-71 238.7 0.0 6.7e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42141.1 - 7e-32 110.5 0.0 8.7e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42141.1 - 5.4e-05 22.2 0.2 0.00079 18.4 0.1 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EDP42141.1 - 0.00021 20.7 0.2 0.00033 20.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDP42141.1 - 0.00042 20.1 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP42141.1 - 0.0019 17.3 0.1 0.0031 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3114 PF11311.3 EDP42141.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) 3Beta_HSD PF01073.14 EDP42142.1 - 5e-55 186.1 0.0 3.3e-51 173.6 0.0 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDP42142.1 - 1.4e-28 99.9 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDP42142.1 - 1.7e-12 46.8 0.0 1.3e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDP42142.1 - 2.5e-10 40.6 0.0 2.4e-09 37.4 0.0 2.4 1 1 1 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EDP42142.1 - 4.3e-09 35.6 0.0 7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EDP42142.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EDP42142.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EDP42142.1 - 0.015 14.9 0.1 0.03 13.9 0.1 1.6 1 1 0 1 1 1 0 KR domain zf-CHY PF05495.7 EDP42143.1 - 8e-14 51.5 10.6 1.2e-13 51.0 7.4 1.2 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.1 EDP42143.1 - 0.0096 15.3 6.0 1.7 8.1 1.6 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR Zn_Tnp_IS1595 PF12760.2 EDP42143.1 - 0.019 14.7 8.5 0.42 10.4 3.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 EDP42143.1 - 0.029 14.0 0.4 0.029 14.0 0.3 2.0 2 0 0 2 2 1 0 Zinc finger found in FPG and IleRS DZR PF12773.2 EDP42143.1 - 0.064 13.0 7.8 0.37 10.6 5.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EDP42143.1 - 0.23 11.0 0.3 0.23 11.0 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DRP PF06044.7 EDP42143.1 - 0.29 10.0 1.8 0.51 9.2 0.2 1.9 1 1 1 2 2 2 0 Dam-replacing family Zn-ribbon_8 PF09723.5 EDP42143.1 - 0.31 11.0 11.0 0.3 11.0 1.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EDP42143.1 - 0.36 10.1 4.9 11 5.4 3.4 2.4 1 1 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EDP42143.1 - 0.37 10.1 5.2 1.4 8.2 0.7 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 EDP42143.1 - 0.72 9.5 7.2 3.8 7.2 5.1 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RING_3 PF14369.1 EDP42143.1 - 0.79 9.7 9.2 0.34 10.9 1.7 2.7 1 1 2 3 3 2 0 zinc-finger HypA PF01155.14 EDP42143.1 - 1.3 8.7 7.1 12 5.5 4.9 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 EDP42143.1 - 3.4 7.7 8.9 7.2 6.6 2.0 2.6 1 1 0 2 2 2 0 TFIIH C1-like domain DUF3797 PF12677.2 EDP42143.1 - 5.1 6.7 5.6 11 5.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zinc_ribbon_4 PF13717.1 EDP42143.1 - 8.7 6.1 12.9 11 5.7 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain ACBP PF00887.14 EDP42144.1 - 1.3e-33 114.5 0.5 1.8e-33 114.0 0.3 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein IFN-gamma PF00714.12 EDP42144.1 - 0.0051 16.6 0.1 2.5 7.9 0.0 2.1 1 1 1 2 2 2 2 Interferon gamma DUF1145 PF06611.7 EDP42145.1 - 0.028 14.0 2.0 0.088 12.4 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) Methyltransf_23 PF13489.1 EDP42147.1 - 1.1e-12 48.0 0.0 4.6e-12 45.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP42147.1 - 2.9e-11 43.7 0.0 1.3e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP42147.1 - 2e-08 34.5 0.0 1.3e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42147.1 - 5.7e-08 32.4 0.0 2.9e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP42147.1 - 2.4e-07 31.0 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP42147.1 - 3.1e-07 30.9 0.0 5.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDP42147.1 - 3e-05 23.1 0.0 0.00061 18.8 0.0 2.1 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EDP42147.1 - 4.6e-05 23.4 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDP42147.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EDP42147.1 - 0.003 18.3 0.0 0.0083 16.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDP42147.1 - 0.022 14.4 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LCM PF04072.9 EDP42147.1 - 0.036 13.6 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase FmrO PF07091.6 EDP42147.1 - 0.063 12.2 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ham1p_like PF01725.11 EDP42148.1 - 5.6e-25 87.8 0.0 3e-20 72.3 0.0 2.0 1 1 1 2 2 2 2 Ham1 family Glycos_transf_4 PF00953.16 EDP42149.1 - 1.2e-29 103.2 8.9 1.2e-29 103.2 6.2 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 TPR_11 PF13414.1 EDP42150.1 - 9e-07 28.4 3.1 0.0085 15.7 0.0 4.5 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 EDP42150.1 - 2.3e-05 24.2 1.6 0.0071 16.2 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42150.1 - 3.4e-05 23.4 1.0 0.35 10.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP42150.1 - 0.00033 20.1 0.0 0.18 11.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP42150.1 - 0.0022 17.6 0.6 0.28 11.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP42150.1 - 0.032 14.6 0.4 9.3 6.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDP42150.1 - 0.19 11.9 6.0 2 8.8 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDP42150.1 - 0.23 12.1 26.9 1.4 9.6 0.2 5.5 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDP42151.1 - 2.9e-14 52.4 14.1 4.8e-08 32.5 0.0 6.1 4 2 2 6 6 6 3 TPR repeat TPR_19 PF14559.1 EDP42151.1 - 1.1e-08 35.2 21.6 0.0047 17.2 0.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDP42151.1 - 1.9e-07 30.6 0.5 0.0024 17.9 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42151.1 - 4.6e-07 29.8 47.7 0.0024 18.3 1.5 9.7 7 3 4 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42151.1 - 4.7e-07 29.2 17.0 1 9.4 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP42151.1 - 6.1e-07 28.7 1.1 1.3 8.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42151.1 - 1.7e-05 24.6 25.3 0.0012 18.7 0.3 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP42151.1 - 4.6e-05 23.9 43.2 0.0038 17.8 0.2 8.2 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDP42151.1 - 6.8e-05 22.3 0.0 7.7 6.5 0.0 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP42151.1 - 0.00014 22.0 9.1 2.7 8.6 0.0 6.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP42151.1 - 0.0032 17.2 18.6 0.041 13.7 0.8 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDP42151.1 - 0.079 12.7 4.0 1.3 9.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EDP42151.1 - 0.083 13.0 0.1 0.083 13.0 0.0 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF4398 PF14346.1 EDP42151.1 - 0.17 11.9 2.5 0.29 11.2 0.0 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF4398) TPR_11 PF13414.1 EDP42152.1 - 2.2e-11 43.2 7.3 1.6e-06 27.6 0.9 2.0 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 EDP42152.1 - 1.2e-06 28.9 6.5 0.00054 20.5 0.4 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP42152.1 - 1.7e-05 24.2 0.2 5.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42152.1 - 2.3e-05 23.9 2.3 5.2e-05 22.8 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP42152.1 - 4.8e-05 22.8 1.5 0.00049 19.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42152.1 - 0.0012 19.2 3.0 0.03 14.9 0.1 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDP42152.1 - 0.012 15.3 0.5 0.033 14.0 0.2 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDP42152.1 - 0.048 13.8 0.3 0.46 10.8 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP42152.1 - 0.13 12.3 2.3 0.16 12.1 0.8 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDP42152.1 - 0.16 11.9 4.1 0.15 12.0 0.7 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EDP42153.1 - 2.4e-63 212.9 0.1 3.5e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDP42153.1 - 6.1e-37 125.8 0.0 1.5e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EDP42153.1 - 1.1e-21 76.4 0.0 2.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EDP42153.1 - 9.6e-13 47.7 0.0 2.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDP42153.1 - 1.4e-12 47.5 0.0 9.7e-12 44.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP42153.1 - 2.6e-05 24.1 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NARP1 PF12569.3 EDP42154.1 - 7.7e-166 552.8 15.5 1.1e-147 492.9 9.2 2.6 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EDP42154.1 - 5.9e-10 38.3 19.4 3.8e-05 23.2 0.1 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDP42154.1 - 3.6e-09 36.1 13.1 0.0016 18.0 0.1 5.9 4 1 1 5 5 5 3 TPR repeat TPR_9 PF13371.1 EDP42154.1 - 4e-08 32.9 17.6 0.00021 21.0 0.6 6.5 7 1 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP42154.1 - 7.5e-07 29.3 11.3 0.0018 18.5 0.3 6.4 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42154.1 - 3.9e-05 23.9 22.5 9.7 7.1 2.0 10.1 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDP42154.1 - 9.3e-05 22.9 0.6 9.3e-05 22.9 0.4 8.5 10 1 0 10 10 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDP42154.1 - 9.8e-05 22.1 1.3 11 5.9 0.0 4.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EDP42154.1 - 0.00018 21.0 5.9 0.0027 17.2 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.2 EDP42154.1 - 0.0034 17.4 0.1 0.11 12.4 0.0 3.0 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_12 PF13424.1 EDP42154.1 - 0.0055 16.6 19.3 0.0057 16.5 0.0 5.7 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP42154.1 - 0.016 14.9 4.0 1.7 8.6 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP42154.1 - 0.047 13.5 10.1 0.17 11.7 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDP42154.1 - 5.3 7.1 12.4 1.1 9.3 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Pkinase PF00069.20 EDP42155.1 - 2.8e-66 223.3 0.0 3.9e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42155.1 - 9e-29 100.3 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDP42155.1 - 1.1e-11 44.9 1.8 3.2e-11 43.5 1.3 1.8 1 1 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 EDP42155.1 - 3.6e-09 36.3 0.0 6.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 EDP42155.1 - 2.5e-08 33.2 0.0 1.1e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDP42155.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PP-binding PF00550.20 EDP42156.1 - 3.7e-14 52.7 0.3 5.3e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EDP42156.1 - 1.4e-06 28.2 0.6 2e-06 27.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EDP42156.1 - 0.027 14.5 0.2 0.043 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L17 PF01196.14 EDP42157.1 - 2.3e-10 40.8 0.1 1.3e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L17 RICTOR_M PF14666.1 EDP42157.1 - 0.051 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Bcl-2_BAD PF10514.4 EDP42157.1 - 0.15 11.9 1.9 0.2 11.5 1.3 1.2 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD DUF1751 PF08551.5 EDP42158.1 - 2.2e-11 43.9 3.9 4.6e-11 42.9 2.7 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF4052 PF13261.1 EDP42158.1 - 0.42 10.0 13.2 0.11 11.8 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4052) DUF2417 PF10329.4 EDP42158.1 - 1.2 8.4 9.0 1.9 7.8 6.2 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) WD40 PF00400.27 EDP42159.1 - 1.2e-62 205.6 17.6 1.7e-09 37.1 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDP42159.1 - 0.001 18.5 0.0 5.5 6.5 0.0 5.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EDP42159.1 - 0.0013 16.9 0.0 0.0043 15.2 0.0 1.9 2 1 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EDP42159.1 - 0.0015 18.3 0.0 0.08 12.6 0.0 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 EDP42159.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_S7 PF00177.16 EDP42160.1 - 1e-38 132.2 0.3 1.2e-38 131.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CtaG_Cox11 PF04442.9 EDP42161.1 - 6.8e-54 181.7 0.1 8.5e-54 181.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DKCLD PF08068.7 EDP42162.1 - 3.6e-28 97.2 0.0 1.8e-27 95.0 0.0 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EDP42162.1 - 3e-23 82.6 6.5 3.5e-22 79.1 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EDP42162.1 - 7e-21 73.7 0.6 1.3e-20 72.8 0.4 1.5 1 0 0 1 1 1 1 PUA domain Ribosomal_L22e PF01776.12 EDP42163.1 - 2.6e-44 149.8 0.1 3.3e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Spb1_C PF07780.7 EDP42164.1 - 1.5e-68 230.5 21.0 1.5e-68 230.5 14.6 4.0 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 EDP42164.1 - 2.1e-52 177.7 0.0 4.2e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EDP42164.1 - 1.7e-45 154.3 2.7 1.7e-45 154.3 1.9 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) DUF148 PF02520.12 EDP42164.1 - 0.49 10.2 8.3 0.26 11.1 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 eIF2A PF08662.6 EDP42165.1 - 8e-41 139.8 0.2 4.3e-37 127.7 0.0 4.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EDP42165.1 - 0.00012 21.8 5.6 0.86 9.5 0.0 6.1 8 0 0 8 8 8 1 WD domain, G-beta repeat RRM_1 PF00076.17 EDP42165.1 - 0.00027 20.4 0.0 0.00075 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42165.1 - 0.00081 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lgl_C PF08596.5 EDP42165.1 - 0.074 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal PEX11 PF05648.9 EDP42166.1 - 1.1e-63 214.5 1.8 1.2e-63 214.3 1.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RepC PF06504.6 EDP42166.1 - 0.056 12.3 0.1 0.15 11.0 0.0 1.6 1 1 0 2 2 2 0 Replication protein C (RepC) DNApol3-delta_C PF09115.5 EDP42166.1 - 0.06 13.3 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Sel1 PF08238.7 EDP42167.1 - 7.3e-09 35.9 24.2 0.0013 19.2 0.2 6.6 5 2 0 5 5 5 5 Sel1 repeat TPR_1 PF00515.23 EDP42167.1 - 0.36 10.5 2.6 13 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Deltaretro_Tax PF05599.6 EDP42168.1 - 0.00092 19.4 0.8 0.0025 18.0 0.5 1.9 1 1 0 1 1 1 1 Deltaretrovirus Tax protein Ribosomal_L32p PF01783.18 EDP42168.1 - 0.0011 19.0 1.6 0.0018 18.3 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family ICL PF00463.16 EDP42169.1 - 1e-94 317.6 1.4 1.2e-94 317.4 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family ICL PF00463.16 EDP42170.1 - 6.6e-147 489.8 0.2 7.9e-147 489.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDP42170.1 - 3.7e-10 39.4 0.0 4.8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EDP42170.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain DUF367 PF04034.8 EDP42171.1 - 1.4e-42 144.3 0.0 1.8e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EDP42171.1 - 1.3e-13 50.2 0.2 2.1e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 EDP42171.1 - 0.004 15.7 4.4 0.0054 15.2 3.1 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EDP42171.1 - 0.034 12.0 13.6 0.058 11.3 9.4 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 EDP42171.1 - 1.1 8.6 5.1 1.7 8.1 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EDP42171.1 - 1.6 6.6 8.6 2.2 6.2 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EDP42171.1 - 8.2 4.4 7.9 11 3.9 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Prenyltrans PF00432.16 EDP42173.1 - 2.7e-40 135.5 7.0 5.5e-11 41.8 0.1 4.2 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDP42173.1 - 4.6e-23 81.7 0.0 3e-12 46.9 0.0 2.9 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDP42173.1 - 4.5e-06 26.6 0.1 1.5e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Prenyltransferase-like MutS_V PF00488.16 EDP42174.1 - 1.6e-75 253.5 0.4 3e-75 252.6 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EDP42174.1 - 1.4e-37 129.4 4.8 2.6e-37 128.6 3.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDP42174.1 - 2.8e-09 36.9 0.0 6.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EDP42174.1 - 1.4e-08 34.8 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EDP42174.1 - 7.6e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EDP42174.1 - 0.054 13.0 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb6 PF01192.17 EDP42175.1 - 4.4e-21 74.3 0.2 6.2e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Sod_Cu PF00080.15 EDP42175.1 - 0.099 12.7 0.5 0.35 10.9 0.4 1.8 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) AMP-binding PF00501.23 EDP42176.1 - 2.3e-48 164.6 0.0 3.6e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EDP42176.1 - 5.6e-11 42.5 0.8 1.5e-10 41.2 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDP42176.1 - 1.4e-10 41.9 0.4 4.5e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep PF00132.19 EDP42176.1 - 5.8e-08 31.8 12.7 0.0012 18.2 0.1 7.2 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.8 EDP42176.1 - 0.2 10.1 0.0 4.3 5.7 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hexapep_2 PF14602.1 EDP42176.1 - 4.8 6.8 14.5 6.3 6.4 0.0 5.5 5 1 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase Hepar_II_III PF07940.8 EDP42177.1 - 1e-07 31.8 2.3 1.3e-07 31.5 0.2 2.1 2 0 0 2 2 2 1 Heparinase II/III-like protein TPPK_C PF12555.3 EDP42177.1 - 0.0087 15.7 2.8 0.0087 15.7 2.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphokinase C terminal DUF1628 PF07790.6 EDP42177.1 - 0.15 12.8 0.7 0.66 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) SDF PF00375.13 EDP42177.1 - 0.33 9.6 0.0 0.51 9.0 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Pkinase PF00069.20 EDP42178.1 - 2.8e-35 121.7 0.0 4.5e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42178.1 - 1.8e-13 50.1 0.0 3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42178.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42178.1 - 0.027 14.2 0.2 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Carn_acyltransf PF00755.15 EDP42180.1 - 2.7e-143 478.1 0.0 3.3e-143 477.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Gluconate_2-dh3 PF13618.1 EDP42180.1 - 0.17 12.0 3.0 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 Hydrolase_4 PF12146.3 EDP42181.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 EDP42181.1 - 0.091 12.6 0.1 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_2 PF00152.15 EDP42182.1 - 9.1e-83 277.8 0.1 1.2e-82 277.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDP42182.1 - 3.7e-05 23.5 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDP42182.1 - 0.023 13.9 0.2 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Tubulin_C PF03953.12 EDP42183.1 - 6.5e-40 136.0 0.0 8.3e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain RecT PF03837.9 EDP42183.1 - 0.038 13.2 0.1 0.067 12.4 0.1 1.3 1 0 0 1 1 1 0 RecT family Tubulin PF00091.20 EDP42184.1 - 5.4e-55 186.5 0.0 6.6e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 EDP42184.1 - 0.0035 16.8 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 EDP42184.1 - 0.082 11.8 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Cupin_8 PF13621.1 EDP42185.1 - 1.4e-15 57.4 0.0 1e-13 51.3 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDP42185.1 - 5.2e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EDP42185.1 - 0.00081 19.0 0.5 0.002 17.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 EDP42185.1 - 0.005 16.1 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.28 EDP42185.1 - 0.039 13.6 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 F-box domain Cupin_2 PF07883.6 EDP42185.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain TLD PF07534.11 EDP42186.1 - 2.3e-22 79.4 0.0 3.8e-19 69.0 0.0 3.4 2 1 0 2 2 2 2 TLD RhoGEF PF00621.15 EDP42187.1 - 3.2e-42 144.4 0.1 4.8e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EDP42187.1 - 8.4e-09 34.8 5.7 9.4e-07 28.3 0.2 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP42187.1 - 3.2e-06 26.7 2.8 0.00062 19.4 0.4 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EDP42187.1 - 1.4e-05 24.4 6.3 4.5 7.6 0.0 5.5 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EDP42187.1 - 0.0045 16.9 4.6 12 6.6 0.1 5.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EDP42187.1 - 0.049 13.7 2.0 0.22 11.6 0.0 3.2 4 0 0 4 4 4 0 Leucine Rich repeat CPSF_A PF03178.10 EDP42188.1 - 1e-80 271.2 0.0 7.7e-80 268.3 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EDP42188.1 - 6.6e-69 232.3 0.0 9.8e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term AdoMet_MTase PF07757.8 EDP42189.1 - 3.2e-33 114.1 0.3 3.4e-32 110.8 0.2 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EDP42189.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ins_P5_2-kin PF06090.7 EDP42191.1 - 2.1e-16 59.8 0.0 2.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MAPEG PF01124.13 EDP42192.1 - 4.2e-16 58.7 0.3 6.2e-16 58.1 0.2 1.4 1 1 0 1 1 1 1 MAPEG family DUF2962 PF11176.3 EDP42193.1 - 4.9e-34 117.1 0.2 5.8e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) L31 PF09784.4 EDP42193.1 - 0.14 12.1 0.7 0.27 11.3 0.5 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 ADH_zinc_N PF00107.21 EDP42194.1 - 5.5e-17 61.5 0.3 8.8e-17 60.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDP42194.1 - 4.7e-07 30.7 1.3 6.9e-07 30.2 0.2 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 EDP42194.1 - 0.029 14.3 0.1 0.066 13.2 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_N PF08240.7 EDP42194.1 - 0.03 14.0 0.0 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Tetraspannin PF00335.15 EDP42195.1 - 6e-05 22.4 5.0 9.3e-05 21.8 3.5 1.5 1 1 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 EDP42195.1 - 1.2 8.9 8.1 1.8 8.4 5.5 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4131 PF13567.1 EDP42195.1 - 1.3 8.4 4.2 0.69 9.3 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.26 EDP42196.1 - 3.9e-08 33.2 1.2 9.7e-08 31.9 0.9 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP42196.1 - 0.058 13.5 2.7 0.24 11.5 0.6 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Bud13 PF09736.4 EDP42197.1 - 1.4e-38 132.4 4.6 1.4e-38 132.4 3.2 2.4 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex zf-Nse PF11789.3 EDP42199.1 - 5.1e-14 51.5 0.0 9.3e-14 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDP42199.1 - 9.8e-08 31.5 0.1 5.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RING-type zinc-finger U-box PF04564.10 EDP42199.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 EDP42199.1 - 0.0062 16.2 0.1 0.024 14.4 0.0 1.9 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EDP42199.1 - 0.0086 15.8 0.1 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP42199.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm PF00514.18 EDP42199.1 - 0.078 12.8 0.0 0.38 10.6 0.0 2.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat zf-C3HC4_4 PF15227.1 EDP42199.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CTP_synth_N PF06418.9 EDP42201.1 - 9.8e-94 313.4 0.2 2.3e-54 184.3 0.9 2.1 1 1 1 2 2 2 2 CTP synthase N-terminus GATase PF00117.23 EDP42201.1 - 7.1e-49 165.8 0.0 1e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDP42201.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EDP42201.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Steroid_dh PF02544.11 EDP42202.1 - 1.8e-15 57.0 1.4 8.1e-14 51.6 1.0 2.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SF3b10 PF07189.6 EDP42203.1 - 6.7e-27 93.1 0.0 7.8e-27 92.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SNF2_N PF00176.18 EDP42204.1 - 1.5e-70 237.3 1.4 2.9e-70 236.4 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EDP42204.1 - 1.3e-53 180.7 15.7 1.3e-53 180.7 10.9 3.4 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EDP42204.1 - 4.1e-13 48.9 0.0 9.4e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP42204.1 - 1.5e-05 24.9 0.0 6.3e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pex14_N PF04695.8 EDP42205.1 - 5.9e-06 26.3 0.0 5.9e-06 26.3 0.0 3.1 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1485 PF07364.7 EDP42205.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Adaptin_N PF01602.15 EDP42206.1 - 2e-108 363.0 0.0 3.3e-108 362.2 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EDP42206.1 - 2.8e-49 166.7 0.1 5.7e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EDP42206.1 - 1.1e-13 51.2 2.9 0.00022 21.4 0.0 5.6 2 2 4 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 EDP42206.1 - 0.00046 20.4 2.1 3.2 8.4 0.2 5.4 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Arm PF00514.18 EDP42206.1 - 0.0045 16.7 1.4 54 3.8 0.0 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EDP42206.1 - 0.01 15.8 12.4 0.34 11.1 0.1 6.1 7 0 0 7 7 7 0 HEAT repeat Cnd1 PF12717.2 EDP42206.1 - 0.39 10.5 2.5 12 5.6 0.0 3.4 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EDP42206.1 - 3.4 8.2 8.6 3.4 8.2 0.4 4.0 3 1 1 4 4 4 0 HEAT-like repeat bZIP_2 PF07716.10 EDP42207.1 - 2.6e-08 33.5 14.2 2.6e-08 33.5 9.9 2.4 3 1 0 3 3 3 1 Basic region leucine zipper HALZ PF02183.13 EDP42207.1 - 7.1e-05 22.4 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 EDP42207.1 - 0.00011 22.0 11.4 0.00036 20.4 7.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDP42207.1 - 0.0096 16.2 5.9 0.0096 16.2 4.1 3.2 3 0 0 3 3 3 1 bZIP Maf transcription factor TSC22 PF01166.13 EDP42207.1 - 0.049 13.6 0.0 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Phlebovirus_NSM PF07246.6 EDP42207.1 - 0.1 11.7 0.8 0.19 10.8 0.6 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M NOA36 PF06524.7 EDP42207.1 - 0.82 8.8 3.5 1.3 8.2 2.5 1.2 1 0 0 1 1 1 0 NOA36 protein XhlA PF10779.4 EDP42207.1 - 3.5 7.6 7.4 0.39 10.6 1.5 2.0 2 0 0 2 2 2 0 Haemolysin XhlA mRNA_cap_enzyme PF01331.14 EDP42208.1 - 1.8e-26 93.0 0.1 2.1e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EDP42208.1 - 8.1e-13 48.6 0.4 2.1e-12 47.2 0.3 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EDP42208.1 - 0.0003 20.2 0.3 0.0069 15.7 0.1 2.8 2 1 0 2 2 2 1 ATP dependent DNA ligase domain mRNA_cap_C PF03919.10 EDP42209.1 - 7.9e-12 45.4 0.0 1.4e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.14 EDP42209.1 - 2.7e-05 23.9 0.0 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Sugar_tr PF00083.19 EDP42210.1 - 1.2e-95 320.7 24.3 1.8e-94 316.8 16.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP42210.1 - 3.2e-09 35.9 41.3 3e-06 26.2 15.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EDP42210.1 - 0.27 10.7 2.1 5 6.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF697) MFS_1 PF07690.11 EDP42211.1 - 1.9e-12 46.6 51.0 1.9e-09 36.7 23.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP42211.1 - 0.00042 19.0 15.3 0.00042 19.0 10.6 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter ParA PF10609.4 EDP42213.1 - 4.9e-31 106.4 0.1 1.1e-30 105.3 0.1 1.5 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EDP42213.1 - 1.6e-07 30.9 0.1 2.4e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EDP42213.1 - 0.055 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ubie_methyltran PF01209.13 EDP42213.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_2 PF00890.19 EDP42214.1 - 8.6e-126 420.1 4.8 1.1e-125 419.7 3.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EDP42214.1 - 1e-47 161.1 1.4 1.6e-47 160.6 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EDP42214.1 - 1.3e-05 25.1 0.5 0.0039 17.1 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDP42214.1 - 1.4e-05 24.3 0.1 0.0078 15.3 0.1 2.6 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EDP42214.1 - 3.7e-05 22.7 1.7 0.037 12.9 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EDP42214.1 - 7.5e-05 21.7 0.4 0.0032 16.4 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDP42214.1 - 0.015 14.3 0.3 0.032 13.2 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EDP42214.1 - 0.045 13.7 1.4 4.8 7.1 0.3 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP42214.1 - 0.32 9.4 3.9 0.56 8.6 0.7 2.6 3 0 0 3 3 3 0 HI0933-like protein DUF1690 PF07956.6 EDP42215.1 - 0.0003 20.7 3.1 0.00042 20.2 2.2 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Mnd1 PF03962.10 EDP42215.1 - 0.0011 18.6 5.2 0.0015 18.2 3.6 1.2 1 0 0 1 1 1 1 Mnd1 family DUF608 PF04685.8 EDP42215.1 - 0.003 16.3 0.4 0.0033 16.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Peptidase_M91 PF14891.1 EDP42215.1 - 0.027 14.5 0.3 0.03 14.3 0.2 1.1 1 0 0 1 1 1 0 Effector protein DUF4239 PF14023.1 EDP42215.1 - 0.034 13.5 1.4 0.077 12.3 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) rve_3 PF13683.1 EDP42215.1 - 0.042 13.3 0.4 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain ATP-synt_F6 PF05511.6 EDP42215.1 - 0.07 13.0 1.1 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Gon7 PF08738.5 EDP42215.1 - 0.21 11.5 2.8 0.34 10.9 1.9 1.5 1 1 0 1 1 1 0 Gon7 family APG6 PF04111.7 EDP42215.1 - 0.24 10.4 6.0 0.3 10.1 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Strep_SA_rep PF06696.6 EDP42215.1 - 0.34 10.7 4.4 0.31 10.8 0.4 2.7 2 1 1 3 3 3 0 Streptococcal surface antigen repeat IncA PF04156.9 EDP42215.1 - 1.1 8.7 5.0 1.2 8.6 3.5 1.1 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 EDP42215.1 - 3.4 7.6 8.4 6.8 6.6 5.8 1.5 1 1 0 1 1 1 0 FlxA-like protein zf-C2HC5 PF06221.8 EDP42216.1 - 2.2e-11 43.3 3.1 3.6e-11 42.6 2.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cupin_8 PF13621.1 EDP42217.1 - 1.3e-09 37.9 0.1 4.4e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDP42217.1 - 3.1e-06 27.3 0.4 0.00014 22.0 0.0 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase efThoc1 PF11957.3 EDP42218.1 - 3.2e-62 210.6 0.0 8e-62 209.3 0.0 1.6 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RRM_1 PF00076.17 EDP42219.1 - 6.4e-13 48.1 0.0 1.7e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42219.1 - 7.1e-13 48.3 0.0 1.7e-12 47.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42219.1 - 8.2e-08 31.9 0.0 3.9e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ubiquitin PF00240.18 EDP42220.1 - 2.4e-35 119.7 1.2 7.9e-35 118.0 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EDP42220.1 - 5.8e-24 83.6 0.4 1.1e-23 82.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EDP42220.1 - 1.1e-19 69.8 0.5 2e-19 69.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDP42220.1 - 4.4e-06 26.8 0.5 2.6e-05 24.3 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDP42220.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDP42220.1 - 0.00044 20.0 0.6 0.001 18.9 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDP42220.1 - 0.0054 16.9 0.6 0.0071 16.5 0.4 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 EDP42220.1 - 0.02 13.2 3.3 0.32 9.2 0.2 2.2 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EDP42220.1 - 0.047 13.7 0.6 0.091 12.8 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) IBR PF01485.16 EDP42220.1 - 0.07 13.0 0.8 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 IBR domain Pkinase PF00069.20 EDP42221.1 - 7.9e-57 192.3 0.0 1.1e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42221.1 - 4.3e-20 71.8 0.0 7.5e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDP42221.1 - 0.1 11.3 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1713 PF08213.6 EDP42222.1 - 4.7e-13 48.4 23.9 4.7e-13 48.4 16.6 2.5 4 0 0 4 4 4 1 Mitochondrial domain of unknown function (DUF1713) PepSY_2 PF13670.1 EDP42222.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_L2_C PF03947.13 EDP42223.1 - 8.7e-45 151.7 1.3 8.4e-43 145.2 0.9 2.2 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDP42224.1 - 2.2e-12 46.7 3.2 5.5e-12 45.4 0.2 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Skp1_POZ PF03931.10 EDP42225.1 - 1.7e-24 85.6 0.1 2.7e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 EDP42225.1 - 9.2e-16 57.6 0.3 1.8e-15 56.7 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.26 EDP42225.1 - 0.0069 16.3 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain DUF3535 PF12054.3 EDP42226.1 - 1.6e-83 280.8 3.1 2.9e-80 270.0 0.5 4.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EDP42226.1 - 1.3e-70 237.5 0.0 2.1e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP42226.1 - 3.5e-12 45.9 0.0 8.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EDP42226.1 - 3.5e-05 23.5 11.2 0.25 11.5 0.0 7.5 7 1 1 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EDP42226.1 - 4.7e-05 23.7 0.3 0.36 11.2 0.1 3.0 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region HDA2-3 PF11496.3 EDP42226.1 - 0.00063 18.6 0.4 0.0034 16.2 0.3 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Trypan_PARP PF05887.6 EDP42226.1 - 0.0027 17.5 1.4 0.0027 17.5 1.0 1.7 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) HEAT_EZ PF13513.1 EDP42226.1 - 1.4 9.4 26.2 1.2 9.6 0.0 8.4 9 0 0 9 9 9 0 HEAT-like repeat CIA30 PF08547.7 EDP42227.1 - 3e-21 75.9 0.0 3.7e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Tim44 PF04280.10 EDP42228.1 - 9.9e-29 100.2 0.1 1.2e-27 96.6 0.0 2.5 3 0 0 3 3 3 1 Tim44-like domain Seryl_tRNA_N PF02403.17 EDP42228.1 - 0.051 13.5 2.0 0.085 12.8 1.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SQS_PSY PF00494.14 EDP42228.1 - 0.29 10.3 4.7 1.3 8.2 0.1 3.0 2 1 0 3 3 3 0 Squalene/phytoene synthase DUF2422 PF10337.4 EDP42228.1 - 1.9 7.1 4.1 4.5 5.9 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Smr PF01713.16 EDP42229.1 - 3.1e-09 36.9 0.1 1.7e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 EDP42229.1 - 7.7e-05 22.2 9.3 0.00048 19.7 1.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EDP42229.1 - 0.047 13.1 3.9 4.5 6.8 0.7 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain Paf1 PF03985.8 EDP42230.1 - 6.8e-34 117.3 8.1 1.9e-23 82.9 0.1 2.2 2 0 0 2 2 2 2 Paf1 FCP1_C PF09309.5 EDP42230.1 - 0.00018 20.9 11.9 0.00018 20.9 8.2 2.7 3 0 0 3 3 3 1 FCP1, C-terminal UCH_1 PF13423.1 EDP42231.1 - 4.8e-31 108.2 0.0 6.8e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EDP42231.1 - 5.5e-21 75.5 0.0 3.1e-20 73.0 0.0 2.2 2 1 0 2 2 2 1 Exonuclease UCH PF00443.24 EDP42231.1 - 3.2e-05 23.1 0.0 8e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EDP42231.1 - 0.018 14.9 0.2 1.2 9.0 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF718 PF05336.8 EDP42232.1 - 0.043 13.6 1.5 0.069 12.9 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF718) Peptidase_M9_N PF08453.5 EDP42232.1 - 0.11 11.8 0.2 0.29 10.4 0.1 1.7 2 0 0 2 2 2 0 Peptidase family M9 N-terminal DUF2419 PF10343.4 EDP42233.1 - 0.00053 19.3 0.0 0.47 9.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2419) VHS PF00790.14 EDP42234.1 - 5.8e-36 123.2 2.2 7.9e-36 122.7 0.6 1.7 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 EDP42234.1 - 5e-16 58.0 0.9 9.5e-16 57.1 0.3 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EDP42234.1 - 2.8e-15 55.4 0.0 5.3e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDP42234.1 - 8e-12 44.4 0.1 1.5e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 EDP42234.1 - 3.8e-05 23.6 0.7 3.8e-05 23.6 0.5 2.7 3 0 0 3 3 3 1 GAT domain Hrs_helical PF12210.3 EDP42234.1 - 0.006 16.8 0.7 0.02 15.1 0.5 1.9 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.15 EDP42234.1 - 0.012 15.1 1.3 0.012 15.1 0.9 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif TPR_11 PF13414.1 EDP42235.1 - 2.6e-12 46.1 0.2 2.6e-12 46.1 0.2 3.2 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EDP42235.1 - 1.1e-06 27.9 1.1 0.0026 17.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 EDP42235.1 - 1.5e-06 27.8 0.0 6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 EDP42235.1 - 9.8e-06 25.2 0.1 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 EDP42235.1 - 0.00015 21.3 8.8 0.0087 15.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42235.1 - 0.0077 16.1 0.2 0.0077 16.1 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EDP42236.1 - 3.4e-41 140.5 0.8 4.8e-41 140.0 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDP42236.1 - 1.4e-13 51.0 0.5 7.3e-13 48.7 0.0 2.4 2 1 1 3 3 3 1 PCI domain RPN7 PF10602.4 EDP42237.1 - 0.0066 15.8 0.2 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 SNAP PF14938.1 EDP42237.1 - 0.023 13.8 0.6 0.053 12.6 0.4 1.7 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP Aha1_N PF09229.6 EDP42238.1 - 1.1e-29 103.0 0.0 1.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EDP42238.1 - 3.2e-18 66.0 0.0 7.6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EDP42238.1 - 6.1e-05 23.2 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Apolipoprotein PF01442.13 EDP42240.1 - 0.025 14.0 0.0 2.7 7.4 0.0 2.6 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1428 PF07237.6 EDP42240.1 - 0.036 13.9 1.8 0.065 13.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) DUF1967 PF09269.6 EDP42240.1 - 0.046 13.3 0.2 18 5.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Phe_tRNA-synt_N PF02912.13 EDP42240.1 - 0.15 11.8 0.3 7 6.4 0.0 2.6 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain ATP-cone PF03477.11 EDP42240.1 - 0.22 11.9 2.3 5.1 7.5 0.1 2.5 1 1 1 2 2 2 0 ATP cone domain DUF883 PF05957.8 EDP42240.1 - 0.35 11.2 6.9 9 6.7 0.7 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 EDP42240.1 - 2.9 8.0 10.9 1.8 8.6 1.3 3.0 1 1 2 3 3 3 0 MT0933-like antitoxin protein Tape_meas_lam_C PF09718.5 EDP42240.1 - 4.9 7.1 8.3 16 5.4 0.0 3.7 3 1 1 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 EDP42240.1 - 5.8 7.3 5.9 1.6e+02 2.7 4.1 2.5 1 1 0 1 1 1 0 YtxH-like protein COX7C PF02935.11 EDP42241.1 - 0.023 14.4 0.2 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc MSA-2c PF12238.3 EDP42241.1 - 0.3 10.7 4.9 0.4 10.3 3.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c E_Pc_C PF06752.7 EDP42241.1 - 0.46 9.9 11.5 0.55 9.6 7.9 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DnaJ PF00226.26 EDP42242.1 - 4.8e-18 64.6 1.3 1.1e-17 63.5 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Macoilin PF09726.4 EDP42242.1 - 0.18 10.0 8.7 0.2 9.8 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Cyclin_N PF00134.18 EDP42243.1 - 5.1e-06 26.0 0.1 1.1e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain MatE PF01554.13 EDP42244.1 - 2.2e-44 150.9 26.2 4e-26 91.5 7.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EDP42244.1 - 3.3e-07 30.2 7.8 3.3e-07 30.2 5.4 3.9 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain UCR_6-4kD PF08997.5 EDP42244.1 - 0.84 9.3 4.4 3.3 7.5 3.1 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein CoatB PF10389.4 EDP42244.1 - 1.2 9.0 4.8 0.2 11.5 0.5 1.9 2 0 0 2 2 2 0 Bacteriophage coat protein B Mito_carr PF00153.22 EDP42245.1 - 1.1e-24 85.9 1.4 6.5e-17 61.0 0.2 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein DEAD PF00270.24 EDP42246.1 - 1.5e-43 148.2 0.0 2.9e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDP42246.1 - 4.2e-24 83.8 0.5 1.8e-23 81.8 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDP42246.1 - 3.7e-21 74.7 0.0 8.2e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EDP42246.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 EDP42246.1 - 0.016 15.0 0.1 0.079 12.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPT PF03151.11 EDP42248.1 - 1.7e-30 105.6 10.1 1.7e-30 105.6 7.0 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EDP42248.1 - 5.1e-17 62.0 19.1 1.1e-10 41.6 3.6 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EDP42248.1 - 3e-15 55.9 13.5 3.8e-15 55.5 9.4 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EDP42248.1 - 6.5e-09 35.2 9.3 6.2e-06 25.5 0.8 2.5 2 1 0 2 2 2 2 Nucleotide-sugar transporter CRA PF06589.6 EDP42248.1 - 0.12 11.7 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) UPF0546 PF10639.4 EDP42248.1 - 0.37 10.6 8.8 3.2 7.6 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Multi_Drug_Res PF00893.14 EDP42248.1 - 1 9.8 8.6 0.17 12.3 1.4 2.6 2 1 0 2 2 2 0 Small Multidrug Resistance protein Bac_export_2 PF01312.14 EDP42248.1 - 1.9 7.2 7.7 0.16 10.8 1.1 2.1 1 1 0 2 2 2 0 FlhB HrpN YscU SpaS Family EmrE PF13536.1 EDP42248.1 - 5.6 7.2 22.1 0.93 9.7 2.3 3.0 3 1 1 4 4 4 0 Multidrug resistance efflux transporter BAG PF02179.11 EDP42249.1 - 1.1e-13 51.1 0.2 3.1e-13 49.6 0.1 1.8 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EDP42249.1 - 2.4e-06 26.8 0.4 6.4e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EDP42249.1 - 0.0085 16.3 0.1 0.38 11.0 0.0 3.0 3 1 0 3 3 3 1 Ubiquitin-like domain SAS4 PF15460.1 EDP42249.1 - 0.052 13.4 0.2 0.5 10.2 0.1 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 zf-TFIIIC PF12660.2 EDP42250.1 - 5.1e-19 68.0 6.4 1.2e-18 66.7 4.4 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DnaJ-X PF14308.1 EDP42251.1 - 1.1e-62 210.9 0.2 1.1e-62 210.9 0.2 2.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDP42251.1 - 1.6e-20 72.5 2.0 2.2e-20 72.1 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4613 PF15390.1 EDP42251.1 - 1.3 7.1 4.7 2 6.4 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ribosomal_S4e PF00900.15 EDP42252.1 - 2.8e-29 100.5 0.2 5.5e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EDP42252.1 - 1.6e-17 63.0 4.2 1.6e-17 63.0 2.9 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EDP42252.1 - 0.0026 17.1 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 EDP42252.1 - 0.07 12.8 2.9 0.096 12.4 0.7 2.3 2 0 0 2 2 2 0 KOW motif CwfJ_C_2 PF04676.9 EDP42253.1 - 4.2e-17 62.4 0.1 2.2e-16 60.1 0.1 2.0 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EDP42253.1 - 1e-05 25.1 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Zip PF02535.17 EDP42255.1 - 1.5e-51 175.2 6.9 1.8e-51 175.0 4.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ArgJ PF01960.13 EDP42256.1 - 3.9e-120 400.8 0.0 5.2e-120 400.4 0.0 1.1 1 0 0 1 1 1 1 ArgJ family Thioredoxin_8 PF13905.1 EDP42257.1 - 2.8e-06 27.3 0.0 7.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like LIP PF03583.9 EDP42258.1 - 2.4e-49 168.0 0.0 3.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase SelP_N PF04592.9 EDP42258.1 - 3.4 6.9 12.7 5.4 6.3 8.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cyclin PF08613.6 EDP42260.1 - 2.2e-35 122.2 1.7 2e-21 76.9 0.2 2.3 2 0 0 2 2 2 2 Cyclin Thiolase_N PF00108.18 EDP42261.1 - 6.9e-84 280.9 2.0 6.9e-84 280.9 1.4 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDP42261.1 - 3.4e-42 142.7 1.0 3.4e-42 142.7 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EDP42261.1 - 0.024 14.6 0.1 0.11 12.5 0.1 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 EDP42261.1 - 1.1 8.6 7.4 0.16 11.3 0.3 2.9 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Histone PF00125.19 EDP42262.1 - 2.5e-13 49.9 0.1 3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDP42262.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EDP42262.1 - 0.00033 20.5 0.1 0.00047 20.0 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EDP42262.1 - 0.00039 20.4 0.1 0.00079 19.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EDP42262.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EDP42263.1 - 4.2e-30 103.6 0.7 6.4e-30 103.0 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDP42263.1 - 3.5e-05 23.8 0.0 5.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDP42263.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDP42263.1 - 0.017 14.8 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated Abhydrolase_6 PF12697.2 EDP42264.1 - 2.3e-18 66.8 0.1 3.1e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42264.1 - 2.5e-14 53.2 0.0 3.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDP42264.1 - 3.1e-14 52.5 0.1 2.3e-13 49.8 0.1 2.3 2 1 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EDP42264.1 - 1.3e-06 28.1 0.0 3e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EDP42264.1 - 0.0013 18.2 0.0 0.041 13.4 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDP42264.1 - 0.0014 17.9 0.0 2.8 7.1 0.0 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDP42264.1 - 0.0036 16.7 0.0 0.034 13.5 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EDP42264.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 EDP42264.1 - 0.074 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_transf_8 PF01501.15 EDP42265.1 - 5.4e-23 81.6 0.0 7.3e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDP42265.1 - 0.039 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.11 EDP42265.1 - 0.043 13.5 0.8 0.19 11.5 0.5 2.0 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF2420 PF10336.4 EDP42266.1 - 1.6e-18 66.3 0.0 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) UCH PF00443.24 EDP42267.1 - 9.8e-78 260.9 0.0 1.4e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP42267.1 - 5e-21 75.4 0.0 4.4e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EDP42267.1 - 7.9e-10 39.0 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Glutaredoxin PF00462.19 EDP42268.1 - 2.9e-19 68.7 0.0 4.2e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EDP42268.1 - 3.1e-14 52.5 0.0 5.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDP42268.1 - 0.00011 22.1 0.1 0.028 14.5 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like GST_N_3 PF13417.1 EDP42268.1 - 0.0019 18.3 0.0 0.0037 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 EDP42268.1 - 0.014 15.2 0.0 0.048 13.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_2 PF13098.1 EDP42268.1 - 0.035 14.2 0.0 0.14 12.3 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin-like domain Phosducin PF02114.11 EDP42268.1 - 0.047 12.4 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosducin ArsC PF03960.10 EDP42268.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 ArsC family TrbC_Ftype PF09673.5 EDP42268.1 - 0.094 12.3 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Nuf2 PF03800.9 EDP42269.1 - 4e-27 95.0 1.2 5.8e-27 94.4 0.3 1.6 2 0 0 2 2 2 1 Nuf2 family Apc13p PF05839.6 EDP42269.1 - 0.02 14.8 1.7 0.084 12.8 0.1 2.4 2 1 0 2 2 2 0 Apc13p protein EzrA PF06160.7 EDP42269.1 - 0.091 10.9 11.5 0.13 10.4 8.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Herpes_UL25 PF01499.11 EDP42269.1 - 0.32 9.2 7.7 0.1 10.9 3.2 1.6 1 1 1 2 2 2 0 Herpesvirus UL25 family PilJ PF13675.1 EDP42269.1 - 0.4 11.0 9.2 0.86 9.9 1.9 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term APG6 PF04111.7 EDP42269.1 - 1 8.3 12.7 0.58 9.1 7.4 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EDP42269.1 - 1.7 8.6 14.7 3 7.7 0.1 3.6 1 1 2 4 4 4 0 DMPK coiled coil domain like Tho2 PF11262.3 EDP42269.1 - 3.7 6.5 6.4 12 4.7 3.4 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Mnd1 PF03962.10 EDP42269.1 - 5.8 6.5 12.5 3 7.4 6.1 2.1 1 1 1 2 2 2 0 Mnd1 family DUF972 PF06156.8 EDP42269.1 - 8 6.8 9.4 7.9 6.8 2.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GHMP_kinases_N PF00288.21 EDP42270.1 - 6.1e-14 51.8 0.1 1.6e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDP42270.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal SAC3_GANP PF03399.11 EDP42271.1 - 4.5e-68 228.8 1.3 6e-68 228.4 0.9 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDP42271.1 - 0.041 13.6 0.7 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF982 PF06169.7 EDP42271.1 - 0.065 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF982) DUF1348 PF07080.6 EDP42271.1 - 0.076 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) AAA_33 PF13671.1 EDP42272.1 - 1.1e-14 54.4 1.3 1.1e-13 51.2 0.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP42272.1 - 4e-06 27.1 0.4 0.00023 21.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP42272.1 - 0.014 16.2 0.2 0.044 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EDP42272.1 - 0.048 12.8 0.8 0.76 8.9 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 EDP42272.1 - 0.071 12.5 0.4 0.19 11.1 0.1 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IalB PF06776.7 EDP42272.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein SKI PF01202.17 EDP42272.1 - 0.084 12.7 0.8 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase AAA_22 PF13401.1 EDP42272.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDP42272.1 - 0.13 11.3 0.4 1.7 7.6 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin WD40 PF00400.27 EDP42273.1 - 5.8e-11 41.8 9.1 0.019 14.8 0.1 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat IGPD PF00475.13 EDP42274.1 - 1.5e-60 203.2 2.6 2.1e-60 202.8 1.8 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SAP PF02037.22 EDP42275.1 - 8.3e-12 44.3 0.7 1.3e-11 43.7 0.5 1.3 1 0 0 1 1 1 1 SAP domain Actin PF00022.14 EDP42276.1 - 1.4e-20 73.1 0.0 4.9e-10 38.3 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EDP42276.1 - 0.023 13.3 0.0 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein SOG2 PF10428.4 EDP42276.1 - 0.64 8.6 5.9 0.94 8.0 4.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3157 PF11355.3 EDP42276.1 - 1.4 8.1 4.4 2.4 7.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) TFIIA PF03153.8 EDP42276.1 - 9.6 5.9 7.5 0.81 9.5 1.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MTHFR PF02219.12 EDP42277.1 - 8.3e-74 248.2 0.0 4.8e-62 209.6 0.0 2.2 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase SMC_Nse1 PF07574.8 EDP42278.1 - 1.8e-20 73.4 0.2 8.5e-19 67.9 0.2 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EDP42278.1 - 9.8e-06 25.4 9.3 2.5e-05 24.1 6.4 1.7 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EDP42278.1 - 0.019 14.7 6.7 0.04 13.7 4.6 1.6 1 0 0 1 1 1 0 Ring finger domain MarR_2 PF12802.2 EDP42278.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 MarR family IBR PF01485.16 EDP42278.1 - 0.21 11.4 3.9 0.44 10.4 2.7 1.5 1 0 0 1 1 1 0 IBR domain Aminotran_1_2 PF00155.16 EDP42279.1 - 4.5e-74 249.5 0.0 5.1e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ubiquitin PF00240.18 EDP42280.1 - 7.5e-35 118.1 0.7 1.3e-34 117.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDP42280.1 - 8.3e-20 70.2 0.7 1.4e-19 69.5 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 EDP42280.1 - 1.4e-08 34.4 8.5 2.4e-08 33.7 5.9 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.1 EDP42280.1 - 1.1e-05 25.5 0.1 4.5e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDP42280.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDP42280.1 - 0.0063 16.3 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDP42280.1 - 0.012 15.8 0.1 0.016 15.4 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDP42280.1 - 0.054 13.5 0.1 0.4 10.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) PX PF00787.19 EDP42281.1 - 1.4e-19 69.9 0.2 2.8e-19 68.9 0.2 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.13 EDP42281.1 - 0.0016 17.9 8.5 0.023 14.2 2.0 2.4 2 0 0 2 2 2 2 BAR domain Vps5 PF09325.5 EDP42281.1 - 0.0049 16.1 8.8 0.017 14.4 0.3 2.3 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 EDP42281.1 - 0.011 15.0 0.7 0.026 13.8 0.5 1.6 1 0 0 1 1 1 0 FAM92 protein AAA PF00004.24 EDP42282.1 - 6.9e-18 65.1 0.0 1.6e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EDP42282.1 - 3.9e-17 62.0 0.0 1.1e-16 60.5 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDP42282.1 - 7e-14 51.7 0.0 1.1e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDP42282.1 - 1e-10 40.9 0.0 5.8e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDP42282.1 - 1.1e-06 28.8 0.1 7.5e-05 22.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDP42282.1 - 2.3e-06 27.3 0.6 7.5e-05 22.4 0.4 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP42282.1 - 2.5e-06 26.7 0.1 1.1e-05 24.5 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDP42282.1 - 3.5e-06 27.1 3.4 0.00017 21.6 2.4 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EDP42282.1 - 3.6e-06 26.6 0.1 1.5e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EDP42282.1 - 7.7e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP42282.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EDP42282.1 - 7e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDP42282.1 - 0.00025 20.0 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EDP42282.1 - 0.00029 20.2 0.0 0.00085 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EDP42282.1 - 0.00036 20.4 0.1 0.0046 16.8 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EDP42282.1 - 0.00036 20.9 0.0 0.00043 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDP42282.1 - 0.0008 19.0 0.7 0.0018 17.9 0.1 1.9 2 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EDP42282.1 - 0.0015 18.5 0.2 0.017 15.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP42282.1 - 0.0015 19.3 0.0 0.0037 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EDP42282.1 - 0.0015 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EDP42282.1 - 0.0016 18.0 0.0 0.0049 16.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDP42282.1 - 0.0017 17.8 0.8 1.1 8.6 0.1 2.4 1 1 1 2 2 2 2 AAA-like domain DEAD PF00270.24 EDP42282.1 - 0.0039 16.7 0.5 0.032 13.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EDP42282.1 - 0.0053 15.9 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDP42282.1 - 0.0083 16.4 0.0 0.021 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDP42282.1 - 0.014 15.2 0.1 0.035 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDP42282.1 - 0.015 14.7 0.2 0.072 12.4 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EDP42282.1 - 0.017 14.1 0.1 0.06 12.3 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EDP42282.1 - 0.019 15.1 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EDP42282.1 - 0.047 13.1 2.0 0.16 11.3 0.0 2.6 4 0 0 4 4 4 0 FtsK/SpoIIIE family PhoH PF02562.11 EDP42282.1 - 0.063 12.4 0.2 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.18 EDP42282.1 - 0.083 11.6 0.2 1.3 7.7 0.1 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_29 PF13555.1 EDP42282.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLASP_N PF12348.3 EDP42283.1 - 9.1e-68 228.0 0.2 2.6e-64 216.7 0.2 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EDP42283.1 - 2.8e-10 39.3 1.7 0.0049 16.8 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EDP42283.1 - 1.5e-09 37.9 5.4 0.00065 19.9 0.1 4.3 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EDP42283.1 - 7.8e-05 23.0 12.1 0.76 10.3 0.1 5.6 5 0 0 5 5 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EDP42283.1 - 0.00028 20.7 0.8 4.7 7.2 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EDP42283.1 - 0.0077 16.0 0.0 6.6 6.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 zf-DHHC PF01529.15 EDP42283.1 - 0.032 13.6 0.1 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DnaJ-X PF14308.1 EDP42283.1 - 0.085 12.1 6.7 4.3 6.5 3.7 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing Ycf1 PF05758.7 EDP42283.1 - 0.31 8.7 3.2 0.43 8.2 2.2 1.1 1 0 0 1 1 1 0 Ycf1 FHIPEP PF00771.15 EDP42283.1 - 0.34 9.2 5.7 0.58 8.4 3.9 1.3 1 0 0 1 1 1 0 FHIPEP family DUF4557 PF15101.1 EDP42283.1 - 2.6 7.8 15.0 6.3 6.5 10.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tim54 PF11711.3 EDP42283.1 - 4.5 5.7 12.8 0.74 8.3 5.8 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 EDP42283.1 - 5.7 6.6 8.8 17 5.0 6.1 1.8 1 0 0 1 1 1 0 FAM176 family HECT PF00632.20 EDP42284.1 - 9.8e-72 241.7 0.0 1.5e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Herpes_LMP1 PF05297.6 EDP42284.1 - 6.9 5.4 10.9 12 4.7 7.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WD40 PF00400.27 EDP42285.1 - 5e-06 26.1 4.2 0.0025 17.6 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 EDP42285.1 - 0.016 13.3 0.2 0.028 12.5 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HA2 PF04408.18 EDP42286.1 - 3.3e-27 94.4 0.0 1.2e-26 92.6 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDP42286.1 - 1.9e-22 79.2 0.0 5.5e-22 77.7 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDP42286.1 - 1.5e-12 47.2 0.0 3.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP42286.1 - 1.6e-07 30.9 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDP42286.1 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDP42286.1 - 0.0057 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 EDP42286.1 - 0.0068 16.0 0.3 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EDP42286.1 - 0.016 15.1 0.1 0.16 11.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDP42286.1 - 0.019 14.6 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase ResIII PF04851.10 EDP42286.1 - 0.035 13.9 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HDC PF02329.11 EDP42286.1 - 0.053 12.1 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine carboxylase PI chain AAA_19 PF13245.1 EDP42286.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EDP42286.1 - 0.087 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EDP42286.1 - 0.095 12.1 0.0 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 EDP42286.1 - 0.12 11.6 0.0 0.3 10.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EDP42286.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Myosin_head PF00063.16 EDP42286.1 - 0.18 9.7 0.0 0.28 9.1 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Asp_protease PF09668.5 EDP42287.1 - 9.9e-59 196.3 0.0 1.5e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EDP42287.1 - 6.7e-11 42.5 0.1 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.1 EDP42287.1 - 3.7e-07 29.5 0.0 7.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain gag-asp_proteas PF13975.1 EDP42287.1 - 1.1e-06 28.3 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EDP42287.1 - 1.8e-06 27.7 0.2 9e-06 25.5 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EDP42287.1 - 1.9e-06 27.8 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Tropomyosin PF00261.15 EDP42287.1 - 0.0095 15.0 0.1 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Tropomyosin UBA PF00627.26 EDP42287.1 - 0.038 13.8 0.6 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain RNB PF00773.14 EDP42288.1 - 1.3e-54 185.6 0.0 2.6e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 RNB domain SHMT PF00464.14 EDP42289.1 - 5.6e-172 571.5 0.0 6.6e-172 571.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EDP42289.1 - 1.7e-07 30.6 0.0 5.5e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDP42289.1 - 0.0054 15.7 0.0 0.015 14.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Apolipoprotein PF01442.13 EDP42289.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Aminotran_5 PF00266.14 EDP42289.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Kin17_mid PF10357.4 EDP42290.1 - 1e-43 147.9 0.1 1.6e-43 147.4 0.1 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Peptidase_M16 PF00675.15 EDP42291.1 - 3e-18 66.0 0.0 5.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDP42291.1 - 1.5e-13 50.8 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain 2-Hacid_dh PF00389.25 EDP42292.1 - 4.5e-20 71.4 0.0 4.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EDP42292.1 - 3.3e-09 36.1 0.0 5.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_5 PF13893.1 EDP42293.1 - 0.01 15.6 0.1 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP42293.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EDP42293.1 - 0.59 9.6 3.9 0.71 9.4 2.7 1.2 1 0 0 1 1 1 0 IncA protein ORC5_C PF14630.1 EDP42294.1 - 3e-51 174.4 0.0 3.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus TIP120 PF08623.5 EDP42294.1 - 0.034 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF2259 PF10016.4 EDP42294.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Oxidored_FMN PF00724.15 EDP42295.1 - 2.6e-49 168.0 0.0 4.2e-42 144.3 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Pribosyl_synth PF14572.1 EDP42295.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain GFO_IDH_MocA PF01408.17 EDP42295.1 - 0.04 14.4 0.0 0.14 12.7 0.0 1.9 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Oxidored_FMN PF00724.15 EDP42296.1 - 5.2e-50 170.3 0.0 9e-43 146.5 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Myb_DNA-binding PF00249.26 EDP42297.1 - 1e-09 38.2 0.0 0.00017 21.6 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP42297.1 - 0.00027 20.9 0.2 0.62 10.2 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain UQ_con PF00179.21 EDP42298.1 - 1.6e-52 176.6 0.0 1.8e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDP42298.1 - 5.1e-05 23.0 0.0 6.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDP42298.1 - 0.00058 19.7 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EDP42298.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain ELO PF01151.13 EDP42299.1 - 9.8e-47 159.3 25.5 1.2e-46 159.0 17.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ada3 PF10198.4 EDP42300.1 - 1.6e-23 82.8 2.1 3.7e-23 81.6 1.5 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 SSF PF00474.12 EDP42301.1 - 5.4e-05 22.0 15.9 0.00023 19.9 11.0 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Cytochrom_B_N PF00033.14 EDP42301.1 - 2.6 7.3 17.5 0.031 13.6 5.1 2.8 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB PPP4R2 PF09184.6 EDP42302.1 - 1.3e-13 51.1 0.0 1.9e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 PPP4R2 Mg_trans_NIPA PF05653.9 EDP42303.1 - 6e-103 343.9 13.6 7.1e-103 343.6 9.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EDP42303.1 - 2.4e-09 37.3 1.4 2.4e-09 37.3 0.9 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EDP42303.1 - 5.4e-05 23.2 6.7 5.4e-05 23.2 4.6 3.2 3 1 0 3 3 3 2 EamA-like transporter family DUF1113 PF06541.6 EDP42304.1 - 0.074 12.8 1.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) VirB8 PF04335.8 EDP42304.1 - 0.29 10.7 3.0 0.17 11.4 0.4 1.8 2 0 0 2 2 2 0 VirB8 protein CAP59_mtransfer PF11735.3 EDP42305.1 - 4.3e-60 202.9 0.0 6.1e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FCH PF00611.18 EDP42306.1 - 6.5e-09 35.8 0.0 2e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain BBP1_C PF15272.1 EDP42306.1 - 0.11 12.0 1.5 0.14 11.6 0.5 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal RhoGAP PF00620.22 EDP42307.1 - 3.5e-05 23.4 0.1 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_60s PF00428.14 EDP42308.1 - 1.3e-28 99.1 12.8 1.5e-28 98.9 8.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MT PF12777.2 EDP42308.1 - 0.047 12.4 0.6 0.052 12.3 0.4 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF3037 PF11236.3 EDP42308.1 - 0.087 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Rnk_N PF14760.1 EDP42308.1 - 0.14 12.2 0.4 0.36 10.9 0.2 1.8 2 0 0 2 2 2 0 Rnk N-terminus Ribosomal_S19 PF00203.16 EDP42309.1 - 5.9e-19 67.4 0.2 1e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EDP42309.1 - 0.0023 17.8 0.0 0.0028 17.5 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH Herpes_UL51 PF04540.8 EDP42309.1 - 0.068 12.7 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL51 protein ERCC4 PF02732.10 EDP42310.1 - 1.3e-25 89.7 0.0 2.2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Cytochrom_C1 PF02167.10 EDP42311.1 - 4e-85 284.9 0.0 4.9e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EDP42311.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III CPSase_L_D2 PF02786.12 EDP42312.1 - 4.8e-54 182.8 0.0 7.6e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EDP42312.1 - 2.2e-23 82.4 0.0 4.5e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDP42312.1 - 4e-20 71.7 0.0 1e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EDP42312.1 - 9.4e-13 48.2 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EDP42312.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDP42312.1 - 0.00078 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EDP42312.1 - 0.0079 15.6 0.0 0.046 13.1 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Asp PF00026.18 EDP42313.1 - 2.2e-23 83.0 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EDP42313.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDP42313.1 - 0.068 13.6 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Grp1_Fun34_YaaH PF01184.14 EDP42314.1 - 8.8e-42 142.7 16.5 1e-41 142.5 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family NADH-u_ox-rdase PF10785.4 EDP42314.1 - 2.1 8.6 5.1 1 9.6 0.8 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Grp1_Fun34_YaaH PF01184.14 EDP42315.1 - 3e-70 235.8 17.2 3.9e-70 235.4 11.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CAAD PF14159.1 EDP42315.1 - 0.031 13.9 0.9 0.067 12.8 0.3 1.9 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Phage_C PF12025.3 EDP42315.1 - 0.098 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage protein C Grp1_Fun34_YaaH PF01184.14 EDP42316.1 - 4.9e-68 228.5 16.8 6.1e-68 228.2 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CAAD PF14159.1 EDP42316.1 - 0.11 12.1 0.3 0.29 10.8 0.2 1.8 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Phosphoesterase PF04185.9 EDP42317.1 - 4.4e-78 263.1 3.6 6.5e-78 262.5 2.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.9 EDP42318.1 - 1.6e-76 257.9 4.6 2.5e-76 257.3 3.2 1.3 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.9 EDP42319.1 - 1.5e-77 261.3 4.3 2e-77 260.9 3.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase PF00394.17 EDP42320.1 - 5.4e-31 107.6 0.0 1e-28 100.2 0.0 3.1 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP42320.1 - 1.4e-30 105.4 8.6 1.4e-21 76.3 0.5 3.9 5 0 0 5 5 5 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDP42320.1 - 3e-29 101.3 4.6 3e-29 101.3 3.2 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDP42321.1 - 8.9e-32 109.2 4.6 3.7e-22 78.2 0.5 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDP42321.1 - 1.7e-29 102.1 5.5 1.7e-29 102.1 3.8 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EDP42321.1 - 2.5e-26 92.4 0.1 1.1e-25 90.4 0.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase RNA_lig_T4_1 PF09511.5 EDP42322.1 - 3.4e-70 235.9 0.0 5.7e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EDP42322.1 - 4.7e-30 104.6 0.0 8.6e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EDP42322.1 - 4.3e-22 78.5 0.0 8.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 EDP42322.1 - 0.046 14.5 0.1 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDP42322.1 - 0.17 11.6 0.2 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain zf-PARP PF00645.13 EDP42324.1 - 0.083 13.1 1.9 0.11 12.7 0.0 2.2 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CbiG_mid PF11761.3 EDP42324.1 - 0.66 10.2 4.3 1 9.6 1.9 2.2 1 1 1 2 2 2 0 Cobalamin biosynthesis central region XPG_I_2 PF12813.2 EDP42325.1 - 2.5e-07 30.4 0.2 7.4e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing RRP7 PF12923.2 EDP42325.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Spore_III_AF PF09581.5 EDP42325.1 - 6.1 6.6 7.3 10 5.9 5.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Choline_kinase PF01633.15 EDP42326.1 - 7.3e-36 123.7 0.0 1.8e-23 83.2 0.0 2.6 2 1 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 EDP42326.1 - 4.8e-09 36.3 0.0 0.0018 18.0 0.0 3.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family MAS20 PF02064.10 EDP42327.1 - 1.9e-07 30.9 3.6 1.9e-07 30.9 2.5 2.5 2 1 0 2 2 2 1 MAS20 protein import receptor Hid1 PF12722.2 EDP42327.1 - 1.5 6.4 5.9 1.3 6.6 4.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3818 PF12825.2 EDP42328.1 - 2.3e-111 371.7 0.6 3.7e-111 371.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDP42328.1 - 1.7e-34 118.3 3.6 7.9e-34 116.2 2.5 2.2 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EDP42328.1 - 1.7e-13 50.3 0.0 5.8e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 PX domain HSP70 PF00012.15 EDP42329.1 - 6.2e-260 863.2 14.8 7.2e-260 863.0 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDP42329.1 - 2.2e-15 56.0 3.8 2e-13 49.6 1.4 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EDP42329.1 - 0.012 15.4 11.4 0.22 11.3 0.8 3.9 4 1 0 4 4 4 0 Cell division protein FtsA Seryl_tRNA_N PF02403.17 EDP42329.1 - 0.029 14.3 6.1 0.097 12.6 4.2 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Hydantoinase_A PF01968.13 EDP42329.1 - 8.4 5.3 12.0 0.2 10.7 0.1 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase YTH PF04146.10 EDP42330.1 - 1.4e-40 138.1 0.0 2.8e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EDP42330.1 - 8.7e-05 22.0 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42330.1 - 0.0023 17.7 0.0 0.0084 15.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42330.1 - 0.14 12.1 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RWD PF05773.17 EDP42331.1 - 9.3e-10 38.3 8.6 1.2e-08 34.7 4.1 2.9 2 1 0 2 2 2 1 RWD domain TP_methylase PF00590.15 EDP42331.1 - 0.034 13.8 0.3 0.077 12.6 0.0 1.8 1 1 1 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2422 PF10337.4 EDP42331.1 - 0.28 9.9 1.3 0.33 9.6 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) RPN7 PF10602.4 EDP42332.1 - 4.3e-16 58.8 0.0 6.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.1 EDP42332.1 - 0.00064 19.6 0.9 0.0016 18.3 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat PCI PF01399.22 EDP42332.1 - 0.0021 18.3 0.0 0.0064 16.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EDP42332.1 - 0.049 13.2 0.5 0.15 11.6 0.4 1.9 1 1 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 EDP42332.1 - 0.066 12.8 1.2 0.34 10.5 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1810 PF08837.6 EDP42332.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) TPR_7 PF13176.1 EDP42332.1 - 0.12 12.2 2.2 0.17 11.7 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42332.1 - 3.9 7.6 7.5 0.23 11.4 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 EDP42333.1 - 1.1e-28 100.2 0.0 2.7e-28 99.0 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EDP42333.1 - 9.6e-12 45.0 0.0 2.5e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 Telomerase activating protein Est1 WD40 PF00400.27 EDP42334.1 - 7.1e-33 111.2 17.1 7.3e-08 32.0 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40 PF00400.27 EDP42335.1 - 7.1e-05 22.5 0.7 0.0069 16.2 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat Lactonase PF10282.4 EDP42335.1 - 0.055 12.5 0.2 0.13 11.2 0.1 1.6 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller CPSF_A PF03178.10 EDP42335.1 - 0.077 12.0 0.1 0.16 11.0 0.1 1.5 1 1 0 1 1 1 0 CPSF A subunit region Glutaredoxin PF00462.19 EDP42336.1 - 9.6e-18 63.9 0.0 1.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EDP42336.1 - 0.0021 18.2 0.0 0.0029 17.8 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EDP42336.1 - 0.0049 17.0 0.1 0.036 14.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDP42336.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.15 EDP42336.1 - 0.027 14.0 0.3 0.19 11.2 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Rib_5-P_isom_A PF06026.9 EDP42337.1 - 5.8e-54 182.0 0.0 7.2e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EDP42337.1 - 0.014 15.0 0.0 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain DUF3606 PF12244.3 EDP42337.1 - 0.076 12.6 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Sugar-bind PF04198.8 EDP42337.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain WD40 PF00400.27 EDP42338.1 - 6.2e-44 146.3 20.6 1.2e-10 40.8 0.1 8.0 8 1 0 8 8 8 7 WD domain, G-beta repeat Kelch_2 PF07646.10 EDP42338.1 - 0.0066 16.1 0.1 0.044 13.5 0.0 2.4 1 0 0 1 1 1 1 Kelch motif PQQ_3 PF13570.1 EDP42338.1 - 0.021 15.1 7.1 0.94 9.8 0.2 5.0 5 1 0 5 5 5 0 PQQ-like domain DUF4613 PF15390.1 EDP42338.1 - 0.039 12.1 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IKI3 PF04762.7 EDP42338.1 - 0.081 10.7 0.1 5 4.8 0.0 2.0 1 1 0 2 2 2 0 IKI3 family Sec10 PF07393.6 EDP42341.1 - 6.8e-72 242.7 2.1 5.6e-71 239.7 1.5 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EDP42341.1 - 0.01 15.4 3.0 0.01 15.4 2.1 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EDP42341.1 - 0.14 11.9 6.5 0.36 10.6 1.5 3.0 2 1 0 2 2 2 0 F-box-like GP40 PF11025.3 EDP42341.1 - 0.17 11.4 0.9 0.3 10.6 0.6 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Spo7 PF03907.8 EDP42342.1 - 4.7e-09 36.1 1.8 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 2 Spo7-like protein BIR PF00653.16 EDP42343.1 - 2.6e-20 72.6 0.7 7.9e-20 71.0 0.5 1.9 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Daxx PF03344.10 EDP42343.1 - 0.8 8.1 32.8 1 7.7 22.7 1.1 1 0 0 1 1 1 0 Daxx Family 60KD_IMP PF02096.15 EDP42344.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein DNA_ligase_OB_2 PF14743.1 EDP42345.1 - 1.3e-22 79.2 0.2 2.3e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 EDP42345.1 - 1e-14 54.4 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EDP42345.1 - 0.076 13.4 0.0 11 6.5 0.0 2.9 3 0 0 3 3 3 0 ATP dependent DNA ligase C terminal region Fer2_3 PF13085.1 EDP42346.1 - 1.1e-32 112.1 0.1 1.7e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDP42346.1 - 4.3e-10 39.7 5.4 4.3e-10 39.7 3.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDP42346.1 - 8.5e-10 38.5 4.6 8.5e-10 38.5 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDP42346.1 - 1.5e-05 25.1 2.3 0.018 15.3 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDP42346.1 - 2.3e-05 24.7 2.3 2.3e-05 24.7 1.6 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDP42346.1 - 7.9e-05 22.3 6.5 0.00011 21.9 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EDP42346.1 - 0.00056 20.2 4.9 0.00056 20.2 3.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EDP42346.1 - 0.0008 19.1 0.4 0.0008 19.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EDP42346.1 - 0.34 11.4 9.0 0.33 11.5 0.5 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_4 PF12800.2 EDP42346.1 - 6.5 7.3 16.9 0.6 10.5 1.7 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain PHP PF02811.14 EDP42347.1 - 2.8e-07 30.5 0.0 4.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 PHP domain IF4E PF01652.13 EDP42349.1 - 2.4e-46 157.3 0.0 3.8e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FAM220 PF15487.1 EDP42349.1 - 0.37 10.1 10.1 0.058 12.7 4.0 1.8 2 0 0 2 2 2 0 FAM220 family ubiquitin PF00240.18 EDP42350.1 - 1.4e-07 30.8 0.3 2.6e-06 26.7 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EDP42350.1 - 0.0023 18.1 0.1 0.17 12.1 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EDP42350.1 - 0.0028 17.3 0.1 0.038 13.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 EDP42350.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 YukD PF08817.5 EDP42350.1 - 0.085 13.4 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Mito_carr PF00153.22 EDP42351.1 - 2.8e-40 135.9 0.2 1.3e-23 82.4 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein HMD PF03201.11 EDP42351.1 - 0.06 13.2 0.0 1.5 8.7 0.0 2.6 2 1 1 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Peptidase_S26 PF10502.4 EDP42352.1 - 1.3e-09 37.6 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EDP42352.1 - 9e-05 22.0 0.0 0.00021 20.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like DUF2917 PF11142.3 EDP42352.1 - 0.068 12.3 0.1 0.26 10.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2917) PAP2 PF01569.16 EDP42353.1 - 7.8e-12 44.9 10.7 1.6e-11 43.9 7.0 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EDP42353.1 - 0.00029 20.4 11.6 0.0027 17.2 8.0 2.4 1 1 0 1 1 1 1 PAP2 superfamily ATP-synt_J PF04911.7 EDP42353.1 - 0.053 12.9 2.8 0.13 11.7 1.9 1.6 1 0 0 1 1 1 0 ATP synthase j chain DUF4070 PF13282.1 EDP42353.1 - 0.14 11.6 0.6 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) DEP PF00610.16 EDP42354.1 - 3.3e-20 71.5 0.1 6.2e-20 70.7 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3608 PF12257.3 EDP42355.1 - 3.4e-67 226.3 0.0 4.1e-45 153.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) Sec23_trunk PF04811.10 EDP42356.1 - 1.2e-73 247.4 0.0 1.7e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDP42356.1 - 4.3e-35 119.2 0.3 8.3e-35 118.3 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDP42356.1 - 9.7e-32 109.3 0.1 1.9e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDP42356.1 - 6.6e-16 57.5 6.3 1.4e-15 56.5 4.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDP42356.1 - 1.5e-12 46.9 0.0 3.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WD40 PF00400.27 EDP42357.1 - 3.7e-11 42.4 17.9 5e-05 23.0 0.8 6.9 5 3 0 5 5 5 4 WD domain, G-beta repeat DUF2094 PF09867.4 EDP42357.1 - 0.025 14.4 0.0 0.72 9.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2094) Nucleoporin_N PF08801.6 EDP42357.1 - 0.079 11.6 0.1 6.5 5.3 0.0 3.0 2 1 0 2 2 2 0 Nup133 N terminal like Ribosomal_L37ae PF01780.14 EDP42358.1 - 7.3e-39 131.5 7.6 9.5e-39 131.1 5.2 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.7 EDP42358.1 - 0.0029 17.4 0.7 0.0044 16.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-C4_ClpX PF06689.8 EDP42358.1 - 0.094 12.2 0.2 0.094 12.2 0.1 1.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger OrfB_Zn_ribbon PF07282.6 EDP42358.1 - 0.15 11.7 1.4 0.25 11.0 0.6 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EDP42358.1 - 0.23 11.3 4.7 0.091 12.5 1.4 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Prok-RING_2 PF14445.1 EDP42358.1 - 3.7 7.5 6.3 18 5.3 3.9 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Sdh5 PF03937.11 EDP42359.1 - 1.2e-23 82.5 0.8 2e-23 81.8 0.5 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase IBN_N PF03810.14 EDP42360.1 - 3.9e-14 52.3 0.0 4.6e-13 48.8 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EDP42360.1 - 1.3e-07 30.5 0.0 3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 EDP42360.1 - 3.6e-05 23.9 1.8 0.046 14.0 0.1 3.3 2 1 1 3 3 3 2 HEAT repeats Xpo1 PF08389.7 EDP42360.1 - 0.0022 17.9 4.7 0.043 13.7 0.0 4.0 4 0 0 4 4 4 1 Exportin 1-like protein DUF1216 PF06746.6 EDP42360.1 - 0.0089 15.8 0.1 0.037 13.8 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1216) Vac14_Fab1_bd PF12755.2 EDP42360.1 - 0.015 15.6 1.9 0.64 10.4 0.0 4.3 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDP42360.1 - 0.044 13.8 5.4 6.7 7.0 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat Rad17 PF03215.10 EDP42361.1 - 2.3e-24 85.9 0.0 5.3e-11 41.9 0.0 3.2 2 1 1 3 3 3 3 Rad17 cell cycle checkpoint protein DAO PF01266.19 EDP42362.1 - 2.2e-43 148.5 0.1 3.8e-43 147.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDP42362.1 - 8.3e-07 28.1 2.4 0.017 13.9 0.8 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EDP42362.1 - 0.00026 20.1 0.5 0.00047 19.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDP42362.1 - 0.00046 20.1 0.2 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP42362.1 - 0.0063 16.5 0.2 0.12 12.4 0.2 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EDP42362.1 - 0.099 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HCaRG PF07258.9 EDP42362.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 HCaRG protein GIDA PF01134.17 EDP42362.1 - 0.11 11.3 0.1 0.63 8.8 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Brix PF04427.13 EDP42363.1 - 2.8e-47 160.8 0.1 3.7e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain ATP-sulfurylase PF01747.12 EDP42363.1 - 0.028 13.7 0.3 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase Ribosomal_L28 PF00830.14 EDP42364.1 - 2e-20 72.3 1.4 8.2e-20 70.4 0.2 2.1 2 0 0 2 2 2 1 Ribosomal L28 family ATP-synt_ab PF00006.20 EDP42365.1 - 3.1e-62 209.8 0.0 4.5e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDP42365.1 - 4e-19 69.1 0.1 8.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDP42365.1 - 3.2e-09 36.8 0.1 7.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDP42365.1 - 0.041 13.7 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 HAS barrel domain DUF561 PF04481.7 EDP42365.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) 4HBT_3 PF13622.1 EDP42366.1 - 1.2e-41 143.1 0.2 1.6e-41 142.7 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EDP42366.1 - 0.0074 15.9 0.0 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA thioesterase Motile_Sperm PF00635.21 EDP42367.1 - 9.9e-26 89.5 0.1 1.5e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 EDP42367.1 - 0.044 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) HN PF00423.14 EDP42368.1 - 0.22 9.7 2.2 0.25 9.5 1.5 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase SelP_N PF04592.9 EDP42368.1 - 0.61 9.4 9.8 0.64 9.3 6.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 EDP42368.1 - 2 7.1 11.4 2.2 7.0 7.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ORC2 PF04084.9 EDP42369.1 - 7.6e-40 136.7 0.0 1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SQS_PSY PF00494.14 EDP42370.1 - 1.2e-42 146.0 0.2 1.7e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pkinase PF00069.20 EDP42371.1 - 4.2e-63 212.9 0.0 5.6e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42371.1 - 3.7e-38 131.0 0.0 5.6e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42371.1 - 2.5e-06 26.6 0.0 4.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EDP42371.1 - 0.013 14.8 0.2 0.03 13.6 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 EDP42371.1 - 0.033 13.0 0.1 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EDP42371.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDP42371.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase RasGEF PF00617.14 EDP42372.1 - 6.1e-41 140.2 0.0 9.5e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDP42372.1 - 4.6e-07 29.8 0.1 1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Mito_carr PF00153.22 EDP42373.1 - 1.5e-50 168.8 0.9 1.9e-17 62.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-oxoacid_dh PF00198.18 EDP42374.1 - 5.6e-79 264.6 0.0 7.8e-79 264.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDP42374.1 - 5.4e-19 67.6 1.4 9.4e-19 66.8 1.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EDP42374.1 - 2.2e-05 23.7 2.6 0.00035 19.8 0.5 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EDP42374.1 - 0.0026 18.0 0.1 0.63 10.4 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EDP42374.1 - 0.004 16.7 0.1 0.29 10.8 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like YL1 PF05764.8 EDP42374.1 - 0.018 14.6 22.2 0.026 14.1 15.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.7 EDP42374.1 - 0.54 10.1 18.6 0.87 9.4 12.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EDP42374.1 - 1.5 8.7 8.1 2.1 8.2 5.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 EDP42374.1 - 1.8 6.9 31.9 2.4 6.5 22.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF935 PF06074.7 EDP42374.1 - 1.8 7.1 8.6 2.5 6.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Ndc1_Nup PF09531.5 EDP42374.1 - 3.5 5.9 5.0 4.7 5.5 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.9 EDP42374.1 - 3.8 5.4 11.7 4.9 5.0 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2397 PF09660.5 EDP42374.1 - 4.5 5.7 9.9 16 3.8 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) DUF1510 PF07423.6 EDP42374.1 - 5.9 6.1 18.6 9 5.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 EDP42374.1 - 7.3 6.4 7.7 12 5.7 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lipoprotein_20 PF13942.1 EDP42375.1 - 0.0024 17.4 0.5 0.0024 17.4 0.3 2.3 2 1 0 2 2 2 1 YfhG lipoprotein AKNA PF12443.3 EDP42375.1 - 0.01 15.8 1.6 0.89 9.6 0.0 2.6 2 0 0 2 2 2 0 AT-hook-containing transcription factor GAS PF13851.1 EDP42375.1 - 0.018 14.2 2.7 0.4 9.8 0.1 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ALIX_LYPXL_bnd PF13949.1 EDP42375.1 - 0.033 13.1 4.0 0.054 12.4 2.7 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV RPA_interact_M PF14767.1 EDP42375.1 - 0.27 12.0 4.0 0.34 11.6 1.1 2.6 2 1 1 3 3 3 0 Replication protein A interacting middle DivIC PF04977.10 EDP42375.1 - 0.29 10.6 3.4 5.4 6.5 0.3 2.9 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EDP42375.1 - 3.2 6.3 7.5 0.68 8.5 1.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein RRF PF01765.14 EDP42375.1 - 3.8 6.9 8.6 0.12 11.8 0.9 2.2 3 0 0 3 3 3 0 Ribosome recycling factor DUF724 PF05266.9 EDP42375.1 - 5.2 6.6 7.9 1.3 8.5 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.10 EDP42375.1 - 5.5 6.9 11.6 11 5.9 8.0 1.5 1 0 0 1 1 1 0 Fez1 PHD PF00628.24 EDP42376.1 - 1.4e-06 27.8 5.5 1.3e-05 24.7 1.7 2.7 2 1 1 3 3 3 1 PHD-finger FdhE PF04216.7 EDP42376.1 - 0.008 15.9 0.3 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation C1_1 PF00130.17 EDP42376.1 - 0.0097 15.6 1.4 0.0097 15.6 1.0 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EDP42376.1 - 0.9 8.9 5.5 0.7 9.2 0.1 2.9 3 0 0 3 3 3 0 PHD-finger Vps51 PF08700.6 EDP42377.1 - 1.5e-12 47.1 0.7 3.7e-12 45.9 0.5 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Flt3_lig PF02947.9 EDP42377.1 - 0.031 14.1 0.2 1.7 8.5 0.0 2.8 2 0 0 2 2 2 0 flt3 ligand Longin PF13774.1 EDP42378.1 - 2.8e-15 55.6 0.0 5.4e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDP42378.1 - 1.6e-14 53.2 0.3 2.6e-14 52.5 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.7 EDP42378.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Pkinase PF00069.20 EDP42380.1 - 1.9e-63 214.0 0.0 3.3e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42380.1 - 2.7e-35 121.6 0.0 1.2e-34 119.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42380.1 - 7.6e-05 21.8 0.0 0.00038 19.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EDP42380.1 - 0.00036 19.4 0.1 0.00061 18.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIC1 PF07064.8 EDP42381.1 - 5.3e-53 180.0 0.0 1e-52 179.1 0.0 1.5 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EDP42381.1 - 0.003 17.3 0.8 3.7 7.5 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 EDP42381.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Mito_carr PF00153.22 EDP42382.1 - 8e-54 179.3 0.2 1.4e-19 69.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF389 PF04087.9 EDP42382.1 - 0.043 13.7 0.4 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Hydrolase PF00702.21 EDP42383.1 - 3.5e-22 79.8 0.0 6.3e-20 72.5 0.0 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP42383.1 - 4.7e-21 75.8 0.0 1.2e-20 74.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDP42383.1 - 5.8e-19 68.0 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EDP42383.1 - 0.00099 19.0 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDP42383.1 - 0.032 13.8 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDP42383.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Pkinase PF00069.20 EDP42384.1 - 1.1e-64 218.0 0.0 1.6e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42384.1 - 5.7e-44 150.1 0.0 1e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EDP42384.1 - 7.7e-21 74.0 0.0 1.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 EDP42384.1 - 0.00038 19.5 0.1 0.002 17.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like RA PF00788.18 EDP42384.1 - 0.00038 20.8 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Planc_extracel PF07595.7 EDP42384.1 - 0.021 14.4 3.6 0.027 14.1 0.8 2.6 2 0 0 2 2 2 0 Planctomycete extracellular Hydantoinase_B PF02538.9 EDP42385.1 - 4.7e-186 619.0 0.0 7.6e-186 618.4 0.0 1.2 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase DPBB_1 PF03330.13 EDP42387.1 - 9.6e-06 25.5 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 EDP42387.1 - 0.022 14.1 14.7 0.027 13.8 10.2 1.1 1 0 0 1 1 1 0 Vta1 like Sugar_tr PF00083.19 EDP42388.1 - 6.8e-98 328.1 8.6 8.2e-98 327.8 6.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP42388.1 - 2.3e-18 66.0 15.5 2.3e-18 66.0 10.8 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EDP42388.1 - 0.011 13.7 0.6 0.023 12.7 0.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.1 EDP42388.1 - 0.23 11.4 9.0 1.6 8.7 0.4 3.4 3 0 0 3 3 3 0 O-antigen ligase like membrane protein TPR_20 PF14561.1 EDP42389.1 - 0.017 15.2 0.0 0.072 13.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3437 PF11919.3 EDP42390.1 - 9e-29 99.0 0.0 2.3e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT_EZ PF13513.1 EDP42390.1 - 0.00022 21.6 0.3 0.11 12.9 0.0 3.5 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EDP42390.1 - 0.00091 19.1 0.2 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 EDP42390.1 - 0.0012 19.0 0.1 0.023 14.9 0.1 2.3 1 1 1 2 2 2 1 HEAT repeats U3snoRNP10 PF12397.3 EDP42390.1 - 0.047 13.6 0.1 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 UPF0061 PF02696.9 EDP42391.1 - 3.9e-88 295.8 0.0 5.7e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Mannosyl_trans PF05007.8 EDP42392.1 - 4.6e-38 131.3 0.3 8e-38 130.5 0.2 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EDP42392.1 - 3.1e-10 39.4 0.0 4.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U CorA PF01544.13 EDP42393.1 - 2e-44 151.8 1.3 2.6e-44 151.4 0.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3826 PF12875.2 EDP42393.1 - 0.019 14.6 0.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) ACT_4 PF13291.1 EDP42393.1 - 0.048 13.9 0.3 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 ACT domain SUR7 PF06687.7 EDP42394.1 - 1.9e-15 57.0 0.8 2.2e-15 56.7 0.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family NADH5_C PF06455.6 EDP42394.1 - 0.034 13.5 1.5 0.046 13.0 1.1 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus DUF2207 PF09972.4 EDP42394.1 - 0.059 11.9 0.2 0.075 11.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF973 PF06157.6 EDP42394.1 - 0.066 12.1 3.2 0.085 11.8 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3149 PF11346.3 EDP42394.1 - 0.093 12.3 3.7 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Claudin_2 PF13903.1 EDP42394.1 - 0.85 9.2 11.8 4.5 6.9 0.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 EDP42394.1 - 2.4 7.9 6.4 3.9 7.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) GPI-anchored PF10342.4 EDP42395.1 - 5.3e-08 33.2 0.0 8.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Acyl-CoA_dh_1 PF00441.19 EDP42396.1 - 2.1e-49 167.4 2.1 3.1e-49 166.9 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDP42396.1 - 6.1e-25 86.4 0.4 1.5e-24 85.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDP42396.1 - 2.9e-24 85.8 0.0 5.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDP42396.1 - 1.6e-16 60.7 0.7 3.2e-16 59.8 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EDP42396.1 - 0.00048 19.5 0.0 0.0024 17.2 0.0 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CBS PF00571.23 EDP42397.1 - 2.9e-35 119.8 8.7 2.7e-08 33.4 0.0 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EDP42397.1 - 0.00084 18.9 0.2 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain TGS PF02824.16 EDP42398.1 - 7.1e-18 64.1 0.1 1.3e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDP42398.1 - 1.2e-17 63.8 0.0 2.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP42398.1 - 7.4e-11 41.5 0.0 1.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDP42398.1 - 0.00041 20.8 0.0 0.0011 19.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDP42398.1 - 0.0013 18.5 0.3 0.54 10.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AAA_28 PF13521.1 EDP42398.1 - 0.0077 16.2 0.2 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EDP42398.1 - 0.031 13.0 0.2 0.075 11.7 0.0 1.7 1 1 1 2 2 2 0 ArgK protein AIG1 PF04548.11 EDP42398.1 - 0.057 12.5 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family LCAT PF02450.10 EDP42399.1 - 2e-56 191.6 0.3 2.6e-56 191.2 0.2 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EDP42399.1 - 0.00026 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP42399.1 - 0.00049 20.0 0.5 0.0011 18.9 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPPK_C PF12555.3 EDP42399.1 - 0.0087 15.7 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal PGAP1 PF07819.8 EDP42399.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 EDP42400.1 - 2.3e-06 26.8 0.0 2.7e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DnaJ PF00226.26 EDP42401.1 - 1.5e-19 69.5 0.1 2.1e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EDP42401.1 - 2.4e-11 42.9 0.3 3.6e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger Peptidase_C48 PF02902.14 EDP42402.1 - 2.2e-36 125.5 0.0 5.6e-36 124.1 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SGT1 PF07093.6 EDP42403.1 - 1e-102 344.4 17.9 8e-102 341.5 12.4 1.9 1 1 0 1 1 1 1 SGT1 protein Complex1_30kDa PF00329.14 EDP42404.1 - 2.8e-36 123.8 0.0 4.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.6 EDP42405.1 - 8.8e-45 152.8 4.7 1.1e-44 152.5 3.3 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF939_C PF11728.3 EDP42405.1 - 0.12 12.2 2.9 0.28 10.9 1.5 1.9 1 1 1 2 2 2 0 DUF939 C-terminal domain Rrp15p PF07890.7 EDP42406.1 - 1.5e-30 105.9 1.7 1.5e-30 105.9 1.2 1.9 2 0 0 2 2 2 1 Rrp15p Nop14 PF04147.7 EDP42406.1 - 0.00036 18.6 21.8 0.00051 18.1 15.1 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EDP42406.1 - 0.00061 18.4 17.4 0.00075 18.1 12.1 1.2 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EDP42406.1 - 0.00094 17.3 18.5 0.0015 16.7 12.8 1.4 1 0 0 1 1 1 1 CDC45-like protein Rep_4 PF05797.6 EDP42406.1 - 0.67 8.6 5.0 1.2 7.7 3.3 1.5 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF4637 PF15470.1 EDP42406.1 - 4.2 6.9 8.1 10 5.7 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RRN3 PF05327.6 EDP42406.1 - 7.8 4.4 16.1 12 3.8 11.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP-grasp_2 PF08442.5 EDP42407.1 - 2.3e-71 239.3 1.1 6.7e-71 237.8 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EDP42407.1 - 1.4e-23 83.1 1.0 5.4e-23 81.2 0.7 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EDP42407.1 - 9.7e-11 41.3 0.5 5e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HipA_N PF07805.7 EDP42407.1 - 0.0027 17.8 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 HipA-like N-terminal domain GARS_A PF01071.14 EDP42407.1 - 0.0056 16.2 0.5 0.014 14.9 0.1 1.9 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.17 EDP42407.1 - 0.018 14.4 0.0 0.051 12.9 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.1 EDP42407.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_S8 PF00410.14 EDP42408.1 - 4.6e-20 71.7 0.0 7.9e-20 71.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Methyltransf_31 PF13847.1 EDP42409.1 - 4.9e-12 45.6 0.0 6.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP42409.1 - 1.7e-11 44.6 0.0 3.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDP42409.1 - 1e-05 25.2 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP42409.1 - 0.00035 20.5 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP42409.1 - 0.0005 20.4 0.0 0.0009 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP42409.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP42409.1 - 0.0097 15.6 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP42409.1 - 0.014 15.8 0.0 0.067 13.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EDP42409.1 - 0.038 12.8 0.0 0.6 8.9 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase MTS PF05175.9 EDP42409.1 - 0.056 12.8 0.0 0.21 10.9 0.0 1.9 1 1 0 2 2 2 0 Methyltransferase small domain Ribosomal_S27e PF01667.12 EDP42410.1 - 8e-24 82.9 2.8 8.5e-24 82.8 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 Zn_Tnp_IS1 PF03811.8 EDP42410.1 - 0.089 12.2 2.0 0.37 10.3 1.3 2.0 1 1 1 2 2 2 0 InsA N-terminal domain Mu-like_Com PF10122.4 EDP42410.1 - 0.19 10.8 1.6 6.9 5.8 0.1 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com DUF3133 PF11331.3 EDP42410.1 - 0.23 11.0 2.4 1.1 8.9 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) zinc_ribbon_5 PF13719.1 EDP42410.1 - 0.32 10.5 2.0 4 7.0 1.4 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDP42410.1 - 0.33 10.6 1.9 3.9 7.2 1.3 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zf-LSD1 PF06943.7 EDP42410.1 - 0.52 9.9 0.2 0.52 9.9 0.2 2.4 3 0 0 3 3 3 0 LSD1 zinc finger zf-C3HC4_3 PF13920.1 EDP42410.1 - 0.7 9.6 2.8 1.3 8.7 1.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L19e PF01280.15 EDP42411.1 - 5.3e-62 207.9 11.3 5.3e-62 207.9 7.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e TFIIS_M PF07500.9 EDP42411.1 - 0.15 12.0 4.9 0.067 13.2 1.8 1.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain DUF2413 PF10310.4 EDP42412.1 - 7e-28 97.6 24.9 8.2e-28 97.3 6.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2413) Metallophos PF00149.23 EDP42413.1 - 3.6e-42 144.0 1.3 5.3e-42 143.4 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Proteasome PF00227.21 EDP42414.1 - 1.9e-32 112.0 0.1 2.8e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit UBA PF00627.26 EDP42415.1 - 8.8e-06 25.4 0.1 8.8e-06 25.4 0.1 2.9 3 0 0 3 3 3 1 UBA/TS-N domain CDK2AP PF09806.4 EDP42415.1 - 0.0044 17.2 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Hydrolase_like PF13242.1 EDP42416.1 - 2.6e-09 36.6 0.0 7.2e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EDP42416.1 - 7.7e-06 26.2 0.0 1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDP42417.1 - 2.5e-06 27.8 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDP42417.1 - 8.2e-05 23.1 0.0 0.0001 22.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP42417.1 - 0.00032 20.9 0.0 0.00037 20.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_1_2 PF13603.1 EDP42417.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 AMPKBI PF04739.10 EDP42418.1 - 2e-25 88.5 0.1 7.9e-25 86.6 0.0 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain zf-Apc11 PF12861.2 EDP42419.1 - 1.8e-23 82.1 10.0 2.3e-23 81.8 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EDP42419.1 - 4.6e-22 77.9 7.6 5.6e-22 77.6 5.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDP42419.1 - 2.6e-07 30.3 14.6 1.8e-06 27.6 10.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDP42419.1 - 5.9e-06 25.8 9.5 1.3e-05 24.6 6.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP42419.1 - 7.1e-05 22.7 8.8 0.00087 19.2 6.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDP42419.1 - 0.0055 16.5 8.4 0.25 11.2 5.8 2.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDP42419.1 - 0.012 15.3 7.7 0.012 15.3 5.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDP42419.1 - 0.018 14.6 10.7 0.15 11.7 7.4 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EDP42419.1 - 0.046 13.6 12.6 0.36 10.8 8.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EDP42419.1 - 0.18 11.9 6.8 0.53 10.4 4.9 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EDP42419.1 - 0.21 11.5 6.1 0.38 10.7 4.2 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.1 EDP42419.1 - 0.36 10.4 11.8 0.066 12.8 1.7 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EDP42419.1 - 0.46 10.5 11.7 0.055 13.4 5.1 1.8 2 1 0 2 2 2 0 RING-like domain RINGv PF12906.2 EDP42419.1 - 0.69 10.0 10.9 0.33 11.0 5.5 2.0 2 1 0 2 2 2 0 RING-variant domain zf-Nse PF11789.3 EDP42419.1 - 0.73 9.4 6.6 1.3 8.6 4.5 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 EDP42419.1 - 0.83 9.1 6.8 5.6 6.4 0.3 3.2 2 1 1 3 3 3 0 RecR protein zf-RING_6 PF14835.1 EDP42419.1 - 2.3 8.0 6.5 0.86 9.4 2.4 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Kinesin PF00225.18 EDP42420.1 - 7e-48 163.0 0.0 1.5e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF4201 PF13870.1 EDP42420.1 - 0.0011 18.4 6.6 0.0011 18.4 4.6 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EDP42420.1 - 0.0039 16.4 0.1 0.0063 15.7 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF641 PF04859.7 EDP42420.1 - 0.19 11.4 12.9 0.088 12.5 0.8 3.2 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.7 EDP42420.1 - 0.84 9.3 16.3 1.9 8.2 11.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EDP42420.1 - 1.2 8.6 7.1 0.13 11.6 1.3 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 EDP42420.1 - 2.1 6.1 6.2 2.9 5.6 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EDP42420.1 - 3.4 7.5 18.8 0.039 13.8 6.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-SNARE PF05008.10 EDP42420.1 - 7 6.8 16.8 1.2 9.3 0.7 3.4 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF603 PF04645.7 EDP42421.1 - 0.0067 16.4 9.8 0.015 15.2 1.9 3.4 3 1 0 3 3 3 1 Protein of unknown function, DUF603 DUF4062 PF13271.1 EDP42421.1 - 0.0089 16.0 1.1 0.11 12.4 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) Fijivirus_P9-2 PF06837.6 EDP42421.1 - 0.29 10.2 0.5 0.59 9.2 0.4 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Atg14 PF10186.4 EDP42421.1 - 0.79 8.6 42.8 0.26 10.2 9.0 4.8 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4363 PF14276.1 EDP42421.1 - 0.81 9.4 10.5 0.072 12.7 2.9 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) NPV_P10 PF05531.7 EDP42421.1 - 0.94 9.7 13.8 1.5 9.1 0.4 4.9 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein MtrG PF04210.8 EDP42421.1 - 1.5 8.5 4.2 2.4 7.9 0.1 3.3 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF948 PF06103.6 EDP42421.1 - 2.2 8.2 12.8 1.6 8.6 0.1 3.9 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF4239 PF14023.1 EDP42421.1 - 3 7.1 7.3 1.4 8.1 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Prominin PF05478.6 EDP42421.1 - 3.8 4.9 8.5 1.2 6.5 1.3 1.9 1 1 0 1 1 1 0 Prominin DUF310 PF03750.8 EDP42421.1 - 4.6 7.4 10.1 0.93 9.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF310) Baculo_PEP_C PF04513.7 EDP42421.1 - 5.9 6.7 9.7 37 4.1 0.5 3.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 EDP42422.1 - 1.3e-64 217.8 0.0 2.2e-64 217.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42422.1 - 1.4e-33 116.1 0.0 1.8e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42422.1 - 7.4e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42422.1 - 0.00034 20.4 0.1 0.53 9.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Rad4 PF03835.10 EDP42424.1 - 2e-24 85.6 0.3 3.8e-24 84.7 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EDP42424.1 - 4.3e-24 84.0 0.0 7.6e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDP42424.1 - 1.9e-15 56.1 0.6 3.2e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDP42424.1 - 1e-12 48.1 0.5 1e-12 48.1 0.4 2.8 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDP42424.1 - 3.8e-09 36.7 0.1 1.4e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily EDR1 PF14381.1 EDP42424.1 - 0.011 15.2 0.1 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF747 PF05346.6 EDP42425.1 - 2.1e-113 378.7 4.1 2.8e-113 378.3 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Herpes_US9 PF06072.6 EDP42425.1 - 2.6 7.9 4.8 0.5 10.2 0.2 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Ebp2 PF05890.7 EDP42427.1 - 5.1e-83 278.4 9.2 5.1e-83 278.4 6.4 2.9 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CENP-B_dimeris PF09026.5 EDP42427.1 - 0.023 14.9 4.5 0.023 14.9 3.1 7.8 3 1 2 5 5 5 0 Centromere protein B dimerisation domain RGS-like PF09128.6 EDP42427.1 - 0.098 12.1 4.1 0.22 10.9 2.9 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Leo1 PF04004.8 EDP42428.1 - 1.7e-54 184.1 5.3 6.4e-54 182.2 3.6 2.0 1 1 0 1 1 1 1 Leo1-like protein Ctr PF04145.10 EDP42428.1 - 5.2 7.1 4.8 1.6 8.7 0.8 2.0 2 0 0 2 2 2 0 Ctr copper transporter family zf-H2C2_2 PF13465.1 EDP42430.1 - 8.3e-10 38.4 16.0 3.8e-06 26.9 3.0 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDP42430.1 - 1.4e-08 34.6 13.1 0.00045 20.4 1.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP42430.1 - 1.9e-05 24.6 12.6 0.0038 17.4 1.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger G6PD_C PF02781.11 EDP42431.1 - 9.6e-111 369.3 0.0 1.3e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EDP42431.1 - 1.7e-37 129.4 0.1 2.5e-37 128.9 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Cas_Csa5 PF09702.5 EDP42431.1 - 0.15 12.1 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Sod_Fe_C PF02777.13 EDP42432.1 - 5.1e-35 119.5 1.3 8.6e-35 118.7 0.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDP42432.1 - 6.4e-18 64.7 5.9 6.4e-18 64.7 4.1 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-RING_2 PF13639.1 EDP42433.1 - 3.4e-09 36.3 7.2 3.4e-09 36.3 5.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EDP42433.1 - 2.7e-08 33.3 2.5 2.7e-08 33.3 1.7 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP42433.1 - 5.8e-08 32.3 5.4 5.8e-08 32.3 3.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDP42433.1 - 9.2e-08 31.9 7.0 9.2e-08 31.9 4.9 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP42433.1 - 2.1e-07 30.5 5.4 2.1e-07 30.5 3.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDP42433.1 - 6.1e-05 22.6 3.0 0.0002 21.0 2.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDP42433.1 - 0.00025 20.8 5.3 0.00025 20.8 3.7 2.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EDP42433.1 - 0.00057 19.6 1.6 0.00057 19.6 1.1 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EDP42433.1 - 0.019 15.0 10.4 0.38 10.8 4.3 3.4 2 1 0 2 2 2 0 RING-H2 zinc finger PhnA_Zn_Ribbon PF08274.7 EDP42433.1 - 0.037 13.8 0.3 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Tmpp129 PF10272.4 EDP42433.1 - 0.038 12.7 5.1 0.059 12.0 3.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Trm112p PF03966.11 EDP42433.1 - 0.16 12.3 1.1 0.54 10.6 0.2 2.3 2 1 0 2 2 1 0 Trm112p-like protein FYVE PF01363.16 EDP42433.1 - 0.41 10.5 9.3 0.14 12.0 3.1 2.4 2 0 0 2 2 2 0 FYVE zinc finger UPF0547 PF10571.4 EDP42433.1 - 0.41 10.3 7.4 0.84 9.3 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C4pol PF14260.1 EDP42433.1 - 1.7 8.6 7.1 0.8 9.7 0.3 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DEAD PF00270.24 EDP42434.1 - 8.1e-36 123.0 0.0 2.1e-35 121.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42434.1 - 1.8e-25 88.5 0.0 2.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP42434.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDP42434.1 - 0.036 13.1 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit G-patch_2 PF12656.2 EDP42436.1 - 3.9e-28 97.1 0.4 9.5e-28 95.8 0.3 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EDP42436.1 - 3.1e-05 23.6 5.4 0.00011 21.9 3.5 2.2 1 1 1 2 2 2 1 G-patch domain Asp PF00026.18 EDP42437.1 - 3.8e-106 354.9 0.0 4.7e-106 354.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDP42437.1 - 6.5e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDP42437.1 - 8.6e-07 28.6 0.0 1.2e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDP42437.1 - 1.6e-05 25.2 0.0 0.051 14.0 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease DUF605 PF04652.11 EDP42438.1 - 0.13 11.6 39.4 0.039 13.3 20.1 2.3 2 0 0 2 2 2 0 Vta1 like DUF936 PF06075.7 EDP42438.1 - 0.64 8.8 48.9 0.039 12.8 23.6 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) BUD22 PF09073.5 EDP42438.1 - 6.2 5.7 54.2 2 7.4 24.4 2.2 2 0 0 2 2 2 0 BUD22 MAD PF05557.8 EDP42440.1 - 2.4e-42 144.9 42.9 2.1e-36 125.3 7.5 2.4 2 1 0 2 2 2 2 Mitotic checkpoint protein Neuropep_like PF15161.1 EDP42440.1 - 0.26 10.7 4.6 11 5.5 0.0 4.9 4 1 1 5 5 5 0 Neuropeptide-like DivIC PF04977.10 EDP42440.1 - 0.33 10.4 30.9 0.77 9.2 0.1 8.3 7 2 1 9 9 9 0 Septum formation initiator Prefoldin_2 PF01920.15 EDP42440.1 - 0.38 10.5 40.2 0.36 10.6 1.4 8.0 6 1 2 8 8 8 0 Prefoldin subunit NPV_P10 PF05531.7 EDP42440.1 - 0.39 11.0 18.0 5.3 7.3 0.0 6.0 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.10 EDP42441.1 - 9.7e-06 25.3 8.1 1.1e-05 25.1 5.1 1.5 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDP42441.1 - 1.3e-05 25.0 9.8 4.9e-05 23.2 6.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDP42441.1 - 0.071 13.4 7.5 0.13 12.5 5.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Transformer PF06495.6 EDP42441.1 - 0.59 9.9 8.4 1.4 8.8 5.8 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein ATG16 PF08614.6 EDP42441.1 - 4.6 7.0 13.0 0.47 10.2 5.7 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TBCA PF02970.11 EDP42442.1 - 2.1e-25 88.6 0.2 2.7e-25 88.2 0.2 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A PMEI PF04043.10 EDP42442.1 - 0.0044 16.9 1.2 0.011 15.6 0.9 1.6 1 1 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Lactamase_B_2 PF12706.2 EDP42443.1 - 2.8e-09 36.7 0.0 1.3e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Nnf1 PF03980.9 EDP42443.1 - 0.12 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Nnf1 Pkinase PF00069.20 EDP42444.1 - 2.2e-32 112.2 0.1 3.5e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42444.1 - 1.1e-14 54.1 0.5 2e-14 53.3 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDP42444.1 - 0.0018 17.1 0.1 0.0018 17.1 0.1 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EDP42444.1 - 0.0039 16.9 0.7 0.11 12.2 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP42444.1 - 0.028 13.3 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EDP42444.1 - 0.06 12.6 4.2 0.49 9.7 0.0 2.7 3 0 0 3 3 3 0 RIO1 family DEAD PF00270.24 EDP42445.1 - 1.2e-46 158.3 0.0 6.9e-46 155.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42445.1 - 2.1e-26 91.5 0.0 2e-25 88.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP42445.1 - 6.9e-06 26.0 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDP42445.1 - 0.0091 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Exo_endo_phos PF03372.18 EDP42446.1 - 0.005 16.8 0.0 0.0052 16.7 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDP42447.1 - 6.2e-10 38.7 0.0 1.7e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDP42447.1 - 5.4e-06 26.5 0.6 7.7e-06 26.0 0.1 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M22 PF00814.20 EDP42448.1 - 1.9e-46 158.7 0.0 2.2e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family zf-RING_5 PF14634.1 EDP42449.1 - 0.00018 21.1 1.5 0.00038 20.1 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDP42449.1 - 0.0036 16.9 0.9 0.01 15.5 0.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EDP42449.1 - 0.0095 15.7 2.1 0.0095 15.7 1.5 1.9 1 1 1 2 2 2 1 Ring finger domain Ribosomal_L30 PF00327.15 EDP42450.1 - 9.1e-13 47.5 0.1 1.2e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e UbiA PF01040.13 EDP42451.1 - 6.5e-26 91.1 11.6 7.9e-26 90.8 8.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 EDP42451.1 - 0.073 13.1 1.5 0.77 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1214 PF06742.6 EDP42452.1 - 1.7e-12 47.7 1.4 2.9e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) Cyclin PF08613.6 EDP42453.1 - 7.6e-10 39.3 1.3 1e-09 38.9 0.1 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EDP42453.1 - 4.1e-09 36.0 0.2 6.5e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_membrane PF00664.18 EDP42454.1 - 2.9e-13 49.8 0.2 3.3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDP42455.1 - 7.5e-58 194.7 0.0 1e-27 97.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDP42455.1 - 9.3e-14 51.4 0.5 9.3e-14 51.4 0.3 1.5 2 0 0 2 2 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 EDP42455.1 - 2.1e-12 47.4 1.5 3.2e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EDP42455.1 - 2.3e-12 46.6 0.5 0.0025 17.1 0.0 4.4 4 1 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDP42455.1 - 7.5e-10 39.6 0.0 4.7e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDP42455.1 - 2.3e-09 36.6 0.0 0.0039 16.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDP42455.1 - 5.6e-07 29.7 0.1 0.0049 17.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EDP42455.1 - 7.1e-07 29.4 0.0 0.58 10.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EDP42455.1 - 9.2e-07 28.6 0.2 0.059 13.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDP42455.1 - 1.3e-05 25.0 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDP42455.1 - 1.7e-05 24.3 0.1 0.1 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDP42455.1 - 4.3e-05 23.8 0.0 0.057 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDP42455.1 - 0.0001 21.0 0.3 0.032 12.8 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_28 PF13521.1 EDP42455.1 - 0.00012 22.0 3.2 0.44 10.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EDP42455.1 - 0.00017 21.1 0.1 1.1 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain DUF258 PF03193.11 EDP42455.1 - 0.00032 19.9 0.0 0.25 10.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EDP42455.1 - 0.00039 20.3 0.0 0.098 12.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EDP42455.1 - 0.0015 18.0 0.2 0.34 10.3 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EDP42455.1 - 0.0039 16.6 0.1 0.63 9.4 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 EDP42455.1 - 0.0055 16.8 0.1 5.8 7.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.15 EDP42455.1 - 0.014 14.1 0.0 0.36 9.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.1 EDP42455.1 - 0.02 14.8 0.4 5.2 7.0 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EDP42455.1 - 0.021 14.5 0.1 6.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EDP42455.1 - 0.023 14.2 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 EDP42455.1 - 0.025 14.2 0.1 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.1 EDP42455.1 - 0.029 13.9 16.3 0.056 13.0 0.0 4.6 5 1 1 6 6 5 0 AAA domain AAA PF00004.24 EDP42455.1 - 0.037 14.2 0.2 20 5.3 0.0 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EDP42455.1 - 0.041 13.8 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EDP42455.1 - 0.049 13.2 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EDP42455.1 - 0.051 12.7 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 EDP42455.1 - 0.052 12.9 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Miro PF08477.8 EDP42455.1 - 0.058 13.8 0.2 7.2 7.1 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein Zeta_toxin PF06414.7 EDP42455.1 - 0.1 11.6 0.1 6.7 5.7 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin HSP70 PF00012.15 EDP42456.1 - 2.4e-06 25.7 2.8 2.8e-06 25.5 1.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Glu_cys_ligase PF04262.9 EDP42456.1 - 0.038 12.4 0.0 0.044 12.2 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase DUF3047 PF11249.3 EDP42456.1 - 0.12 11.7 0.1 0.14 11.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3047) ATP-synt_DE PF00401.15 EDP42456.1 - 0.29 11.0 5.4 5.8 6.8 3.5 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HSP70 PF00012.15 EDP42457.1 - 9.6e-125 416.7 0.8 1.1e-124 416.5 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDP42457.1 - 2.9e-14 52.4 0.1 4e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.6 EDP42457.1 - 0.0033 16.3 0.1 0.0057 15.6 0.0 1.5 2 0 0 2 2 2 1 StbA protein DDR PF08841.5 EDP42457.1 - 0.006 15.4 1.3 0.01 14.6 0.1 1.9 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EDP42457.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Ribosomal_S2 PF00318.15 EDP42458.1 - 3.9e-42 143.8 0.0 5.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 SNF5 PF04855.7 EDP42459.1 - 6.2e-65 219.0 0.1 1e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EDP42459.1 - 0.00055 19.2 3.3 0.0021 17.3 2.3 2.1 1 1 0 1 1 1 1 GATA zinc finger PITH PF06201.8 EDP42460.1 - 3.4e-26 91.8 0.0 4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain TrkH PF02386.11 EDP42461.1 - 6.1e-79 265.1 15.0 4.8e-78 262.1 5.2 2.1 2 0 0 2 2 2 2 Cation transport protein Vps54 PF07928.7 EDP42461.1 - 0.02 15.0 0.1 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Vps54-like protein MYEOV2 PF15004.1 EDP42461.1 - 5 7.7 8.0 29 5.3 3.8 2.4 2 0 0 2 2 2 0 Myeloma-overexpressed-like UPF0016 PF01169.14 EDP42462.1 - 4.9e-24 84.2 14.9 5.1e-20 71.4 5.1 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 EDP42462.1 - 0.0011 18.4 3.3 0.45 9.9 3.5 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF3995 PF13160.1 EDP42462.1 - 0.0032 17.5 4.7 0.11 12.5 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3995) DUF4131 PF13567.1 EDP42462.1 - 0.015 14.6 0.3 0.51 9.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1206 PF06724.6 EDP42462.1 - 0.09 12.5 4.1 1.5 8.6 0.0 3.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) PCMT PF01135.14 EDP42462.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4064 PF13273.1 EDP42462.1 - 0.34 11.0 4.1 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FAM70 PF14967.1 EDP42462.1 - 0.46 9.6 7.0 0.37 9.9 0.1 2.1 2 0 0 2 2 2 0 FAM70 protein DUF204 PF02659.10 EDP42462.1 - 1.3 9.1 11.0 3.6 7.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF Sad1_UNC PF07738.8 EDP42463.1 - 1.3e-27 96.2 0.0 2.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Cellulase PF00150.13 EDP42464.1 - 5.9e-16 58.4 1.1 5.9e-16 58.4 0.8 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RhoGEF PF00621.15 EDP42465.1 - 2.4e-30 105.7 0.0 8.2e-26 90.9 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain Hexapep PF00132.19 EDP42467.1 - 7.1e-12 44.2 7.7 2.5e-07 29.8 0.3 2.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDP42467.1 - 1.4e-05 24.5 3.2 0.00015 21.2 0.8 2.2 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EDP42467.1 - 0.042 12.4 0.1 0.047 12.2 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase NAPRTase PF04095.11 EDP42468.1 - 1.5e-49 168.5 0.0 1.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family EF-hand_6 PF13405.1 EDP42469.1 - 3.2e-07 29.6 0.1 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EDP42469.1 - 5.3e-07 29.6 0.1 0.004 17.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDP42469.1 - 1.2e-05 24.2 0.6 0.041 13.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EDP42469.1 - 0.015 15.1 0.0 6.5 6.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain FNIP_M PF14637.1 EDP42469.1 - 0.047 13.2 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain TAS2R PF05296.8 EDP42470.1 - 0.13 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) UPF0220 PF05255.6 EDP42471.1 - 4.7e-43 146.3 0.0 1.4e-42 144.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) PgpA PF04608.8 EDP42471.1 - 0.013 15.3 0.7 2 8.1 0.3 2.4 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A PLRV_ORF5 PF01690.12 EDP42471.1 - 1.9 7.5 7.8 2.5 7.1 5.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Myb_DNA-binding PF00249.26 EDP42472.1 - 1.9e-22 79.0 2.1 2.4e-11 43.5 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP42472.1 - 3.7e-22 78.1 5.2 1.4e-14 53.9 1.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain PE_PPE_C PF12484.3 EDP42472.1 - 0.019 15.9 0.8 0.034 15.0 0.6 1.5 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal HTH_AsnC-type PF13404.1 EDP42472.1 - 0.02 14.4 0.5 0.12 11.9 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_4 PF13837.1 EDP42472.1 - 0.41 10.8 3.7 6.1 7.0 1.2 2.8 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_Cef PF11831.3 EDP42473.1 - 3.5e-44 150.7 2.4 9.8e-44 149.2 1.6 1.7 1 0 0 1 1 1 1 pre-mRNA splicing factor component Aminotran_1_2 PF00155.16 EDP42474.1 - 2.8e-59 200.9 0.0 3.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDP42474.1 - 0.015 14.0 0.0 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDP42474.1 - 0.019 13.2 0.0 0.066 11.4 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Med17 PF10156.4 EDP42475.1 - 2.1e-09 36.2 0.1 8.9e-05 20.9 0.2 2.3 2 1 0 2 2 2 2 Subunit 17 of Mediator complex FKBP_C PF00254.23 EDP42476.1 - 6e-33 112.7 0.0 7.5e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LSM PF01423.17 EDP42477.1 - 8.5e-13 47.6 0.0 1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain zf-CCCH_2 PF14608.1 EDP42478.1 - 3e-05 23.8 31.3 0.031 14.2 0.2 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type DUF605 PF04652.11 EDP42478.1 - 1.2 8.4 11.0 2.1 7.6 7.6 1.5 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 EDP42479.1 - 0.00046 19.6 0.3 0.0015 18.0 0.2 1.8 2 0 0 2 2 2 1 Vta1 like PseudoU_synth_2 PF00849.17 EDP42480.1 - 1e-21 77.5 0.0 2e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EDP42480.1 - 0.012 15.0 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 S4 domain MMR_HSR1 PF01926.18 EDP42482.1 - 2.3e-11 43.6 0.0 4.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EDP42482.1 - 0.0029 16.5 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EDP42482.1 - 0.018 14.2 0.0 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EDP42482.1 - 0.067 13.0 0.1 0.46 10.2 0.1 2.2 3 0 0 3 3 3 0 Dynamin family Miro PF08477.8 EDP42482.1 - 0.073 13.5 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EDP42482.1 - 0.088 11.9 0.1 0.6 9.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDP42482.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MIF4G PF02854.14 EDP42485.1 - 8.8e-55 185.3 0.2 8.8e-55 185.3 0.1 1.5 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EDP42485.1 - 7.6e-19 67.3 0.5 2.6e-18 65.6 0.3 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EDP42485.1 - 6.3e-12 45.2 1.3 2.8e-11 43.1 0.1 2.3 2 0 0 2 2 2 1 MA3 domain Bromodomain PF00439.20 EDP42487.1 - 3e-10 39.8 0.0 5.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain tRNA-synt_2 PF00152.15 EDP42488.1 - 1.1e-68 231.5 0.0 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDP42488.1 - 2.8e-10 39.9 0.0 5.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1682 PF07946.9 EDP42488.1 - 0.044 12.6 2.9 0.069 11.9 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4539 PF15072.1 EDP42488.1 - 0.062 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Peptidase_S8 PF00082.17 EDP42489.1 - 1.5e-48 165.4 6.4 2.2e-48 164.8 4.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDP42489.1 - 5.6e-07 30.0 0.0 2.6e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Pkinase PF00069.20 EDP42490.1 - 6.1e-70 235.3 0.0 7.6e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42490.1 - 2.7e-34 118.4 0.0 3.7e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDP42490.1 - 0.0028 16.7 0.0 0.0082 15.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP42490.1 - 0.0034 17.1 0.0 0.0065 16.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4505 PF14956.1 EDP42490.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) MIP-T3 PF10243.4 EDP42490.1 - 3.5 5.9 8.0 4.7 5.5 5.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cor1 PF04803.7 EDP42490.1 - 5.8 6.6 6.2 0.38 10.5 0.7 1.6 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region GIT_SHD PF08518.6 EDP42491.1 - 5.3e-21 73.6 22.2 4.5e-13 48.3 2.4 3.8 4 0 0 4 4 4 2 Spa2 homology domain (SHD) of GIT Gpi1 PF05024.10 EDP42491.1 - 0.78 9.3 0.0 1.3 8.6 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) Mito_carr PF00153.22 EDP42492.1 - 1.9e-68 226.2 2.6 2.3e-22 78.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_6 PF14259.1 EDP42493.1 - 7.1e-34 115.6 0.1 1.8e-09 37.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP42493.1 - 3.2e-26 90.7 0.0 1.2e-06 28.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42493.1 - 4.8e-16 58.3 0.0 6.4e-05 22.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ER_lumen_recept PF00810.13 EDP42494.1 - 1.8e-43 148.5 11.7 2.2e-43 148.2 8.1 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EDP42494.1 - 0.54 9.8 4.0 0.24 10.9 0.3 2.2 2 0 0 2 2 2 0 PQ loop repeat NMO PF03060.10 EDP42495.1 - 2.8e-53 181.1 2.9 6.9e-53 179.9 2.0 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDP42495.1 - 1.3e-07 30.8 2.4 0.0048 15.8 1.3 2.3 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EDP42495.1 - 0.084 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Zip PF02535.17 EDP42496.1 - 1.2e-19 70.4 21.8 7e-19 67.9 7.5 3.1 1 1 1 2 2 2 1 ZIP Zinc transporter BCLP PF12304.3 EDP42496.1 - 0.34 10.2 5.3 0.17 11.3 1.9 1.8 2 0 0 2 2 2 0 Beta-casein like protein LRR_4 PF12799.2 EDP42497.1 - 1.4e-11 43.6 1.2 7.6e-10 38.1 0.3 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP42497.1 - 2.5e-08 33.5 1.4 1.1e-07 31.5 0.7 2.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EDP42497.1 - 7e-08 31.4 1.4 0.076 13.0 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EDP42497.1 - 3.7e-06 26.2 6.8 0.48 10.8 0.0 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EDP42497.1 - 0.14 12.3 0.7 24 5.4 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TFIID_30kDa PF03540.8 EDP42498.1 - 1.9e-27 94.7 0.0 3.6e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 EDP42498.1 - 0.00069 19.3 0.3 0.014 15.1 0.0 2.6 3 0 0 3 3 3 1 CBS domain bZIP_1 PF00170.16 EDP42499.1 - 0.00048 20.0 6.6 0.00048 20.0 4.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EDP42499.1 - 0.06 13.6 1.2 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor HALZ PF02183.13 EDP42499.1 - 0.43 10.3 2.0 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EDP42499.1 - 0.98 9.2 11.3 0.21 11.4 2.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SMC_N PF02463.14 EDP42501.1 - 1.9e-64 216.8 0.0 3.1e-64 216.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDP42501.1 - 8.1e-30 103.2 0.0 2.4e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EDP42501.1 - 7.2e-15 55.8 19.9 7.2e-15 55.8 13.8 4.9 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDP42501.1 - 2.8e-12 47.1 0.0 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDP42501.1 - 1.9e-10 40.4 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDP42501.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1617 PF07761.7 EDP42501.1 - 0.081 12.9 1.0 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) DUF106 PF01956.11 EDP42502.1 - 8.6e-34 116.4 0.3 1.1e-33 116.1 0.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Ceramidase PF05875.7 EDP42503.1 - 3.2e-55 187.1 9.0 3.7e-55 186.8 6.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF1691 PF07950.6 EDP42503.1 - 0.018 14.9 1.3 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Pinin_SDK_memA PF04696.8 EDP42504.1 - 8.5e-05 22.1 15.6 0.0015 18.1 5.3 3.1 3 1 0 3 3 3 2 pinin/SDK/memA/ protein conserved region TFIIA PF03153.8 EDP42504.1 - 0.083 12.7 14.1 0.12 12.2 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KfrA_N PF11740.3 EDP42504.1 - 0.12 12.7 20.2 1.6 9.1 5.8 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EPL1 PF10513.4 EDP42504.1 - 0.23 11.6 10.3 0.74 10.0 7.1 1.8 1 1 0 1 1 1 0 Enhancer of polycomb-like Sporozoite_P67 PF05642.6 EDP42504.1 - 0.23 9.2 1.2 0.41 8.4 0.8 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BORG_CEP PF14957.1 EDP42504.1 - 5.3 7.9 7.2 1.8 9.5 2.4 2.2 2 0 0 2 2 2 0 Cdc42 effector OmpH PF03938.9 EDP42504.1 - 7.1 6.5 10.4 2.1 8.2 1.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HAD PF12710.2 EDP42505.1 - 6.4e-17 62.3 0.1 1.9e-16 60.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDP42505.1 - 2.1e-13 51.1 1.8 5.2e-11 43.3 2.1 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP42505.1 - 2.8e-11 43.2 0.0 6.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EDP42505.1 - 9.4e-08 31.3 0.0 2.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EDP42505.1 - 0.015 14.8 0.1 0.051 13.1 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMEM238 PF15125.1 EDP42506.1 - 3 7.7 5.9 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 TMEM238 protein family RNase_T PF00929.19 EDP42507.1 - 1.9e-20 73.8 0.0 3.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RabGAP-TBC PF00566.13 EDP42508.1 - 2.3e-49 167.8 0.0 3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_pol_Rpb8 PF03870.10 EDP42509.1 - 1.2e-41 142.1 0.1 1.4e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.12 EDP42510.1 - 7.3e-27 93.8 0.0 8.9e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase FGGY_C PF02782.11 EDP42511.1 - 1.5e-14 54.1 0.1 4.6e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDP42511.1 - 6.2e-08 32.2 0.5 8.6e-06 25.2 0.4 2.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Chon_Sulph_att PF06566.6 EDP42511.1 - 0.055 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain GSu_C4xC__C2xCH PF09698.5 EDP42511.1 - 0.42 10.8 3.2 2.9 8.1 0.0 3.4 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) HEAT_2 PF13646.1 EDP42512.1 - 3.6e-21 75.2 1.1 4.7e-05 23.5 0.0 7.8 5 3 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EDP42512.1 - 4.8e-21 74.6 23.0 1.2e-10 41.5 0.0 9.5 8 2 2 10 10 10 4 HEAT-like repeat HEAT PF02985.17 EDP42512.1 - 9.8e-20 68.8 20.4 0.00029 20.6 0.0 10.2 11 0 0 11 11 11 6 HEAT repeat Vac14_Fab1_bd PF12755.2 EDP42512.1 - 7e-12 45.5 0.0 0.00081 19.7 0.0 5.6 5 2 1 6 6 5 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EDP42512.1 - 0.00012 21.9 0.4 0.0013 18.5 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 EDP42512.1 - 0.00082 19.3 0.8 0.95 9.4 0.0 4.4 4 1 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 EDP42512.1 - 0.016 13.9 10.8 0.58 8.8 0.0 5.0 4 1 1 6 6 6 0 RNAPII transcription regulator C-terminal DUF3437 PF11919.3 EDP42512.1 - 0.016 14.9 0.2 2 8.2 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3437) Arm PF00514.18 EDP42512.1 - 0.02 14.6 12.3 2.6 7.9 0.0 7.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat eIF3_N PF09440.5 EDP42512.1 - 0.064 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain RNA_pol_3_Rpc31 PF11705.3 EDP42512.1 - 4.9 7.0 14.7 9.4 6.0 10.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 EDP42512.1 - 6.3 4.5 11.6 17 3.1 5.5 2.1 2 0 0 2 2 2 0 Nop14-like family Cpn60_TCP1 PF00118.19 EDP42514.1 - 2e-109 366.4 0.0 3.2e-56 190.9 0.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Saccharop_dh PF03435.13 EDP42515.1 - 6.8e-19 68.0 0.5 1.2e-18 67.3 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EDP42515.1 - 0.0022 18.2 0.2 0.011 16.0 0.1 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EDP42515.1 - 0.004 16.4 1.0 0.0063 15.7 0.7 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDP42515.1 - 0.0053 16.7 0.3 0.014 15.3 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDP42515.1 - 0.051 12.9 0.1 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UPF0086 PF01868.11 EDP42516.1 - 1.5e-09 37.3 0.0 1.9e-08 33.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function UPF0086 RCC1 PF00415.13 EDP42517.1 - 2.6e-31 107.5 6.6 1.1e-08 35.0 0.1 5.9 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EDP42517.1 - 2.9e-12 46.0 4.4 1.1e-11 44.2 3.1 2.1 1 0 0 1 1 1 1 PHD-finger RCC1_2 PF13540.1 EDP42517.1 - 1.2e-11 43.8 26.2 0.00021 20.8 0.4 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat PHD_2 PF13831.1 EDP42517.1 - 0.0011 18.1 0.7 0.0043 16.3 0.5 2.1 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EDP42517.1 - 0.0027 17.4 1.6 0.0027 17.4 1.1 3.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EDP42517.1 - 0.041 13.6 0.1 0.041 13.6 0.0 2.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 EDP42517.1 - 0.07 13.1 0.3 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Reg_prop PF07494.6 EDP42517.1 - 0.098 12.7 0.2 4.3 7.6 0.2 3.2 3 0 0 3 3 3 0 Two component regulator propeller E1-E2_ATPase PF00122.15 EDP42518.1 - 4.9e-72 241.6 1.4 4.9e-72 241.6 1.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDP42518.1 - 1.9e-35 122.0 3.6 5.4e-35 120.5 2.5 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDP42518.1 - 4e-33 115.6 0.0 1.3e-32 113.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP42518.1 - 3.2e-16 59.0 0.0 6.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDP42518.1 - 6.5e-16 59.0 0.0 1.8e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDP42518.1 - 5.1e-15 54.6 0.0 1.3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDP42518.1 - 1.1e-07 31.7 1.3 1.4e-05 24.7 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HSP70 PF00012.15 EDP42519.1 - 1.4e-47 161.9 0.9 5.4e-44 150.1 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein Spc7 PF08317.6 EDP42519.1 - 0.2 10.3 3.6 0.34 9.5 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Sel1 PF08238.7 EDP42520.1 - 0.052 14.2 2.6 65 4.3 0.0 3.9 4 0 0 4 4 4 0 Sel1 repeat Sel1 PF08238.7 EDP42521.1 - 1.4e-12 47.7 13.8 0.12 13.1 0.1 6.5 6 1 0 6 6 6 6 Sel1 repeat TPR_2 PF07719.12 EDP42522.1 - 0.14 12.1 1.9 18 5.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 EDP42522.1 - 1.8 9.2 5.4 17 6.1 0.2 4.0 4 0 0 4 4 4 0 Sel1 repeat Sel1 PF08238.7 EDP42523.1 - 3.9e-12 46.3 10.5 1.3e-05 25.6 0.0 5.6 6 0 0 6 6 6 3 Sel1 repeat DRIM PF07539.7 EDP42524.1 - 2.8e-31 107.8 0.0 7.8e-31 106.3 0.0 1.9 1 0 0 1 1 1 1 Down-regulated in metastasis TRAP_alpha PF03896.11 EDP42524.1 - 7.5 5.4 7.8 1.4 7.8 1.3 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Kri1_C PF12936.2 EDP42525.1 - 2.4e-26 91.5 0.0 2.4e-26 91.5 0.0 4.2 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EDP42525.1 - 1.3e-24 86.3 11.4 1.3e-24 86.3 7.9 4.6 3 2 2 5 5 5 1 KRI1-like family Ret_tiss PF10044.4 EDP42525.1 - 0.013 16.0 4.6 0.52 10.8 0.5 2.7 2 1 0 2 2 2 0 Retinal tissue protein DUF2011 PF09428.5 EDP42525.1 - 4.3 7.2 32.9 0.73 9.7 2.7 3.4 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2011) DUF1980 PF09323.5 EDP42525.1 - 4.4 7.0 4.8 17 5.0 3.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SQS_PSY PF00494.14 EDP42526.1 - 6.7e-33 114.1 0.0 9.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Med15_fungi PF05397.7 EDP42528.1 - 6.1e-20 71.3 3.1 6.1e-20 71.3 2.2 3.6 3 0 0 3 3 3 1 Mediator complex subunit 15 ARID PF01388.16 EDP42528.1 - 4.5e-18 64.8 3.0 7.3e-18 64.2 0.0 2.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF2216 PF10226.4 EDP42529.1 - 0.0042 16.6 0.7 0.0055 16.2 0.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) HALZ PF02183.13 EDP42529.1 - 0.0049 16.5 1.3 0.0049 16.5 0.9 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper ERM PF00769.14 EDP42529.1 - 0.013 14.9 3.3 0.016 14.7 2.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 EDP42529.1 - 0.027 14.4 3.1 0.055 13.4 2.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor SPX PF03105.14 EDP42529.1 - 0.066 12.9 1.3 0.087 12.5 0.9 1.1 1 0 0 1 1 1 0 SPX domain DUF904 PF06005.7 EDP42529.1 - 0.066 13.5 4.9 0.12 12.6 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EDP42529.1 - 0.07 12.7 3.7 0.088 12.4 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3545 PF12065.3 EDP42529.1 - 0.079 12.7 1.4 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) DUF972 PF06156.8 EDP42529.1 - 0.13 12.5 2.7 0.27 11.6 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) eIF_4EBP PF05456.6 EDP42529.1 - 0.22 11.2 1.2 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DivIC PF04977.10 EDP42529.1 - 0.27 10.7 6.5 0.16 11.4 2.8 1.9 2 0 0 2 2 2 0 Septum formation initiator CASP_C PF08172.7 EDP42529.1 - 0.27 10.2 5.8 0.13 11.2 2.2 1.6 1 1 0 1 1 1 0 CASP C terminal Ribosomal_60s PF00428.14 EDP42529.1 - 0.35 11.3 2.7 0.49 10.8 1.2 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein Striatin PF08232.7 EDP42529.1 - 0.49 10.6 5.8 0.52 10.6 3.5 1.4 1 1 0 1 1 1 0 Striatin family bZIP_2 PF07716.10 EDP42529.1 - 1 9.2 8.1 2.4 8.0 4.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EDP42529.1 - 1.3 8.6 7.7 3.2 7.3 5.5 1.6 1 1 0 1 1 1 0 IncA protein DNA_pol_viral_N PF00242.12 EDP42529.1 - 3.3 6.6 5.9 6.1 5.7 4.1 1.4 1 1 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Syntaxin PF00804.20 EDP42529.1 - 4.3 7.5 7.1 8.6 6.5 5.0 1.6 1 1 0 1 1 1 0 Syntaxin tRNA-synt_2b PF00587.20 EDP42530.1 - 1.5e-44 151.5 0.1 2.7e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP42530.1 - 6.3e-19 67.7 0.2 1.1e-18 66.8 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EDP42530.1 - 1.9e-10 40.4 0.0 3.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EDP42530.1 - 9.4e-09 34.9 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain PTPA PF03095.10 EDP42531.1 - 1.1e-69 234.8 0.0 1.4e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GatB_N PF02934.10 EDP42532.1 - 2.3e-75 253.1 0.0 6.4e-71 238.5 0.0 2.1 1 1 1 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EDP42532.1 - 3.9e-30 104.5 0.0 6.1e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 GatB domain SNAP PF14938.1 EDP42533.1 - 2.7e-93 312.1 6.0 3e-93 312.0 4.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Spatacsin_C PF14649.1 EDP42533.1 - 1.1e-06 27.7 1.5 0.00061 18.7 0.1 2.1 2 0 0 2 2 2 2 Spatacsin C-terminus TPR_12 PF13424.1 EDP42533.1 - 0.049 13.5 15.6 2.8 7.9 0.2 4.8 1 1 4 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDP42533.1 - 0.056 13.1 13.1 2.2 7.9 3.6 3.6 1 1 1 3 3 3 0 TPR repeat TPR_7 PF13176.1 EDP42533.1 - 0.059 13.1 10.0 5.4 7.0 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDP42533.1 - 0.085 12.5 3.4 9.1 6.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP42533.1 - 0.25 11.8 9.9 69 4.2 1.2 5.6 4 2 0 4 4 4 0 Tetratricopeptide repeat Remorin_C PF03763.8 EDP42533.1 - 0.43 10.1 7.3 0.83 9.2 1.8 2.5 2 0 0 2 2 2 0 Remorin, C-terminal region Exonuc_VII_S PF02609.11 EDP42533.1 - 0.58 9.9 5.2 3.6 7.4 0.1 3.5 4 0 0 4 4 4 0 Exonuclease VII small subunit Apc3 PF12895.2 EDP42533.1 - 3.5 7.8 9.6 1.5 8.9 0.7 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDP42533.1 - 4.2 8.1 21.0 0.41 11.3 0.9 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat Methyltransf_11 PF08241.7 EDP42534.1 - 3.7e-12 46.5 0.0 7.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP42534.1 - 1.8e-10 40.8 0.0 2.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP42534.1 - 3.8e-10 40.1 0.0 7.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42534.1 - 1e-06 28.4 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDP42534.1 - 2.3e-05 23.6 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EDP42534.1 - 9.3e-05 22.7 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Med5 PF08689.5 EDP42535.1 - 0.017 12.8 0.9 0.1 10.2 0.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit Med5 PK PF00224.16 EDP42536.1 - 7.7e-151 501.5 0.4 1e-150 501.2 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EDP42536.1 - 9.1e-29 99.3 0.0 3.5e-28 97.5 0.0 2.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EDP42536.1 - 3.2e-06 26.1 0.9 1.3e-05 24.1 0.5 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EDP42536.1 - 0.0033 16.3 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.14 EDP42536.1 - 0.063 12.2 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family U32 DUF776 PF05604.6 EDP42537.1 - 0.2 11.8 4.0 0.14 12.3 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF776) Peptidase_M1 PF01433.15 EDP42538.1 - 3.7e-66 223.8 0.0 5.3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 IPPT PF01715.12 EDP42538.1 - 2.2e-47 161.2 0.5 5.6e-27 94.3 0.1 2.4 1 1 0 2 2 2 2 IPP transferase Leuk-A4-hydro_C PF09127.6 EDP42538.1 - 2.7e-39 134.0 0.0 5.3e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EDP42538.1 - 8.5e-14 51.6 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily AAA_17 PF13207.1 EDP42538.1 - 0.0005 20.8 0.0 0.0034 18.2 0.0 2.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP42538.1 - 0.0031 17.3 1.8 0.56 10.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain IPT PF01745.11 EDP42538.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase PhoH PF02562.11 EDP42538.1 - 0.098 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF87 PF01935.12 EDP42538.1 - 0.21 11.4 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EDP42538.1 - 0.25 11.0 0.0 0.47 10.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Autophagy_N PF03986.8 EDP42539.1 - 2.7e-37 127.7 1.2 1.6e-36 125.2 0.9 2.1 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EDP42539.1 - 2.8e-23 81.8 0.0 9e-23 80.2 0.0 1.9 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EDP42539.1 - 7.5e-10 37.7 0.5 1.2e-09 37.0 0.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Herpes_capsid PF06112.6 EDP42539.1 - 6.1 6.8 11.3 0.92 9.5 1.7 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Aconitase PF00330.15 EDP42540.1 - 6.8e-73 245.7 0.1 7.7e-47 159.8 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDP42540.1 - 2.1e-19 69.9 0.0 4.5e-19 68.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EDP42540.1 - 0.076 12.4 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Aconitate hydratase 2 N-terminus IlvN PF07991.7 EDP42541.1 - 1.4e-44 151.3 0.0 2e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EDP42541.1 - 2.2e-41 141.1 0.0 3.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Metallophos PF00149.23 EDP42542.1 - 5.9e-09 35.6 0.1 9.4e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDP42542.1 - 0.0036 17.1 0.0 0.0065 16.3 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EDP42542.1 - 0.0055 14.8 0.2 0.085 10.8 0.0 2.0 2 0 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase LSM PF01423.17 EDP42543.1 - 2.2e-18 65.5 0.0 2.5e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain DDT PF02791.12 EDP42544.1 - 5.8e-10 38.7 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 DDT domain WHIM3 PF15614.1 EDP42544.1 - 0.00031 20.4 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM2 PF15613.1 EDP42544.1 - 0.00031 20.5 0.3 0.00079 19.2 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EDP42544.1 - 0.088 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Abhydrolase_6 PF12697.2 EDP42545.1 - 1.2e-21 77.6 2.2 1.6e-21 77.2 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42545.1 - 1.8e-14 53.7 0.0 4.1e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP42545.1 - 9.6e-12 44.9 0.1 1.3e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EDP42545.1 - 0.00031 20.4 0.1 0.00048 19.7 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EDP42545.1 - 0.00038 20.2 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase DUF676 PF05057.9 EDP42545.1 - 0.00063 19.0 0.1 0.00092 18.5 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 EDP42545.1 - 0.0012 18.3 0.0 0.63 9.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EDP42545.1 - 0.019 14.2 0.1 0.92 8.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EDP42545.1 - 0.053 13.7 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.8 EDP42545.1 - 0.064 12.6 0.0 0.59 9.5 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_L31e PF01198.14 EDP42547.1 - 5.8e-35 118.8 4.5 7.2e-35 118.5 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e GTP_EFTU PF00009.22 EDP42548.1 - 6e-60 201.9 1.1 6.4e-60 201.8 0.2 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDP42548.1 - 1.3e-28 99.0 0.0 3.3e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDP42548.1 - 1.9e-15 56.7 4.9 5.6e-15 55.2 3.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP42548.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDP42548.1 - 0.00024 20.6 0.7 0.00064 19.3 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EDP42548.1 - 0.0047 17.4 0.0 0.0088 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EDP42548.1 - 0.042 13.3 0.1 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EDP42548.1 - 0.092 12.1 1.5 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EDP42548.1 - 0.096 12.9 0.2 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Spt5-NGN PF03439.8 EDP42549.1 - 1.2e-18 66.5 0.0 2.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EDP42549.1 - 1.7e-15 57.4 50.6 2.3e-12 47.3 17.8 3.6 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EDP42549.1 - 5.7e-12 46.0 14.8 5.7e-12 46.0 10.3 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EDP42549.1 - 3.3e-08 32.9 8.4 0.0075 15.9 0.1 5.4 5 0 0 5 5 5 3 KOW motif SAPS PF04499.10 EDP42549.1 - 1.9 7.0 8.8 3.1 6.3 6.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EDP42550.1 - 2.9e-05 22.8 20.4 2.9e-05 22.8 14.2 2.2 2 0 0 2 2 2 1 Daxx Family DNA_pol_phi PF04931.8 EDP42550.1 - 0.62 7.7 42.6 1.2 6.7 29.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi Trypan_PARP PF05887.6 EDP42550.1 - 6.2 6.6 28.1 8.7 6.1 7.0 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 EDP42550.1 - 7.6 5.7 50.8 0.2 10.9 18.5 2.4 2 0 0 2 2 2 0 SDA1 PP2C PF00481.16 EDP42551.1 - 1.2e-33 116.6 0.1 5.7e-31 107.8 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C RRM_1 PF00076.17 EDP42552.1 - 2.9e-16 58.8 0.0 2.7e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42552.1 - 2.4e-09 37.0 0.0 2.4e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42552.1 - 9e-07 28.6 0.0 0.0081 15.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP42552.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif V-ATPase_C PF03223.10 EDP42553.1 - 8.1e-114 380.3 4.5 9.1e-114 380.2 3.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF1524 PF07510.6 EDP42553.1 - 0.096 12.5 1.2 0.22 11.3 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) PTS_2-RNA PF01885.11 EDP42554.1 - 4.2e-39 133.7 0.0 5.3e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DHFR_1 PF00186.14 EDP42555.1 - 6.9e-23 81.0 0.0 1.4e-11 44.2 0.0 3.1 2 1 0 2 2 2 2 Dihydrofolate reductase tRNA-synt_1c PF00749.16 EDP42556.1 - 1.2e-101 339.5 0.0 1.2e-101 339.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDP42556.1 - 6.9e-33 113.7 0.0 1.1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EDP42556.1 - 1.9e-06 28.2 0.1 7.9e-06 26.2 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDP42556.1 - 0.00048 19.9 1.0 0.00048 19.9 0.7 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EDP42556.1 - 0.029 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.20 EDP42556.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain BRF1 PF07741.8 EDP42556.1 - 2.5 8.4 10.5 7.5 6.8 7.2 1.8 1 0 0 1 1 1 0 Brf1-like TBP-binding domain LSM PF01423.17 EDP42557.1 - 1.6e-11 43.5 0.0 2.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain adh_short PF00106.20 EDP42558.1 - 2e-63 213.3 7.6 1.1e-33 116.5 0.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EDP42558.1 - 1.8e-31 109.2 3.5 7e-18 64.9 0.2 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EDP42558.1 - 1e-18 66.9 0.0 2.4e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 EDP42558.1 - 1.6e-13 51.0 0.2 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 EDP42558.1 - 4.8e-11 42.5 0.0 2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 EDP42558.1 - 0.0081 15.2 0.1 1.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Big_1 PF02369.11 EDP42558.1 - 0.022 14.6 1.9 0.083 12.8 1.3 2.0 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) 3HCDH_N PF02737.13 EDP42558.1 - 0.16 11.6 6.4 3.9 7.0 0.3 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NDUFA12 PF05071.11 EDP42559.1 - 2.8e-20 72.7 4.9 3.5e-20 72.4 3.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Polysacc_synt_4 PF04669.8 EDP42560.1 - 3.5e-25 88.4 3.1 2.1e-24 85.9 2.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Asn_synthase PF00733.16 EDP42561.1 - 1.6e-51 175.2 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDP42561.1 - 1.9e-05 24.3 0.0 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDP42561.1 - 0.0001 22.2 0.0 0.00038 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain PRNT PF15174.1 EDP42563.1 - 2 8.1 7.6 1.2 8.8 1.0 2.4 2 0 0 2 2 2 0 Prion-related protein testis-specific MMR_HSR1 PF01926.18 EDP42564.1 - 2e-19 69.6 0.0 6.4e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrmE_N PF10396.4 EDP42564.1 - 2.6e-19 69.2 0.0 6.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EDP42564.1 - 1.5e-16 60.4 1.5 3.3e-16 59.4 0.1 2.3 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 EDP42564.1 - 3.7e-08 32.8 0.1 1.4e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDP42564.1 - 8.2e-06 25.7 0.0 0.00026 20.8 0.0 2.2 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 EDP42564.1 - 2.3e-05 24.8 0.0 5.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDP42564.1 - 0.0067 15.8 0.0 0.35 10.2 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EDP42564.1 - 0.0068 15.8 1.0 0.12 11.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain Arf PF00025.16 EDP42564.1 - 0.0079 15.4 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.11 EDP42564.1 - 0.045 12.8 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 EDP42564.1 - 0.097 12.8 0.1 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EDP42564.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDP42564.1 - 0.12 13.1 0.0 0.47 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDP42564.1 - 0.13 12.2 0.9 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Clathrin_bdg PF15045.1 EDP42565.1 - 0.00043 19.7 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 Clathrin-binding box of Aftiphilin, vesicle trafficking FEZ PF07763.8 EDP42565.1 - 0.0011 18.7 0.5 0.06 13.0 0.1 2.6 1 1 1 3 3 3 1 FEZ-like protein Abhydrolase_6 PF12697.2 EDP42566.1 - 2.9e-27 96.0 0.5 4.3e-27 95.4 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42566.1 - 5.6e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EDP42566.1 - 1.9e-08 34.8 0.0 2.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EDP42566.1 - 3.8e-08 33.1 0.0 1.3e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDP42566.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EDP42566.1 - 0.00089 18.7 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EDP42566.1 - 0.0043 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EDP42566.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EDP42566.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EDP42566.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Aldo_ket_red PF00248.16 EDP42567.1 - 2.8e-55 187.1 0.0 3.3e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Leptin PF02024.10 EDP42567.1 - 0.0018 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Leptin RHH_1 PF01402.16 EDP42567.1 - 0.12 12.2 0.7 11 6.0 0.0 3.4 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family Phosphoesterase PF04185.9 EDP42568.1 - 3.8e-83 279.7 1.3 6.5e-83 278.9 0.9 1.3 1 0 0 1 1 1 1 Phosphoesterase family Lipocalin_3 PF12702.2 EDP42568.1 - 0.061 13.3 1.5 0.91 9.5 0.4 2.5 2 0 0 2 2 2 0 Lipocalin-like Asp PF00026.18 EDP42569.1 - 3.4e-43 148.0 6.0 8.4e-43 146.8 4.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP42569.1 - 4.6e-09 36.6 0.7 9.9e-05 22.7 0.1 2.8 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDP42569.1 - 2.7e-06 27.0 0.0 1.3e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 EDP42570.1 - 9.1e-40 136.8 4.2 5.1e-39 134.3 2.9 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP42570.1 - 0.0033 17.8 2.2 0.99 9.9 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EDP42570.1 - 0.0034 16.9 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EDP42570.1 - 0.06 13.1 0.1 14 5.6 0.0 3.7 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 EDP42571.1 - 2.3e-39 135.4 4.6 6.9e-39 133.9 3.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP42571.1 - 3e-06 27.6 1.8 0.011 16.1 0.3 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EDP42571.1 - 0.0007 19.5 0.6 0.0062 16.5 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.18 EDP42572.1 - 1.1e-23 83.9 0.9 2.7e-23 82.7 0.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP42572.1 - 8.8e-05 22.9 1.3 0.13 12.7 0.2 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EDP42572.1 - 0.046 13.5 0.1 11 5.9 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease bact-PGI_C PF10432.4 EDP42572.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Asp PF00026.18 EDP42573.1 - 1.2e-28 100.2 2.7 2.7e-28 99.1 1.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP42573.1 - 6.3e-08 33.0 0.3 0.0023 18.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EDP42573.1 - 0.0069 16.1 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 EDP42573.1 - 0.052 13.5 0.1 0.81 9.6 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal MvaI_BcnI PF15515.1 EDP42574.1 - 0.00011 22.3 5.3 99 2.8 0.0 6.9 4 1 0 8 8 8 3 MvaI/BcnI restriction endonuclease family PNTB PF02233.11 EDP42576.1 - 0.92 8.2 5.4 0.45 9.2 2.1 1.4 1 1 0 1 1 1 0 NAD(P) transhydrogenase beta subunit DUF155 PF02582.9 EDP42577.1 - 1.5e-49 168.2 0.0 2.3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF218 PF02698.12 EDP42579.1 - 0.0058 16.1 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 DUF218 domain UPF0121 PF03661.8 EDP42580.1 - 9.1e-21 74.1 3.3 1.1e-20 73.8 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CTV_P6 PF06706.6 EDP42580.1 - 1.2 8.6 4.0 4.9 6.7 0.0 3.2 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein Rad51 PF08423.6 EDP42581.1 - 3.8e-10 39.1 0.2 1.6e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 Rad51 KaiC PF06745.8 EDP42581.1 - 0.0015 17.7 0.2 0.0037 16.4 0.1 1.7 2 0 0 2 2 2 1 KaiC RecA PF00154.16 EDP42581.1 - 0.0018 17.4 0.2 0.0046 16.0 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EDP42581.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDP42581.1 - 0.13 12.0 0.1 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain RNA_pol_Rpb1_5 PF04998.12 EDP42582.1 - 3.1e-103 344.8 0.0 4.6e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDP42582.1 - 6.7e-69 231.0 0.0 1.1e-68 230.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EDP42582.1 - 6e-59 198.9 0.0 1.1e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_1 PF04997.7 EDP42582.1 - 1.7e-52 178.7 0.0 2.3e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EDP42582.1 - 1.3e-46 158.2 0.0 2.5e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EDP42582.1 - 4e-46 156.0 0.4 7.6e-46 155.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EDP42582.1 - 1.1e-37 128.0 0.0 2.5e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EDP42582.1 - 1.9e-24 83.5 238.1 0.01 15.9 6.8 17.1 5 4 19 24 24 24 22 RNA polymerase Rpb1 C-terminal repeat UIM PF02809.15 EDP42583.1 - 1.5e-05 24.1 8.5 0.02 14.4 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF4544 PF15077.1 EDP42583.1 - 0.17 11.3 1.2 0.32 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) Hid1 PF12722.2 EDP42584.1 - 2.6e-82 276.9 14.8 1.7e-81 274.2 10.3 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EDP42584.1 - 2.4e-32 111.8 0.0 6.8e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF1757 PF08560.5 EDP42585.1 - 0.04 13.5 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Bacteriocin_IIc PF10439.4 EDP42585.1 - 1.4 9.0 7.1 6.1 7.0 1.8 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Pkinase PF00069.20 EDP42586.1 - 8.6e-71 238.1 0.0 1.7e-70 237.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.8 EDP42586.1 - 7.1e-45 153.1 0.0 1.3e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 EDP42586.1 - 1.7e-30 105.9 0.0 2.6e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 EDP42586.1 - 2.5e-12 46.1 0.0 6.5e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDP42586.1 - 3.9e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family YrbL-PhoP_reg PF10707.4 EDP42586.1 - 0.00064 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EDP42586.1 - 0.0016 17.5 0.0 0.006 15.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDP42586.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EDP42586.1 - 0.03 14.0 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDP42586.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fe-S_biosyn PF01521.15 EDP42587.1 - 3.4e-09 36.6 0.0 4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NAC PF01849.13 EDP42588.1 - 1.5e-15 56.4 0.0 2.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EDP42588.1 - 0.00035 20.3 0.1 0.00058 19.6 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EDP42588.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Proteasome PF00227.21 EDP42589.1 - 1.2e-46 158.4 0.0 1.6e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SNARE_assoc PF09335.6 EDP42590.1 - 1.3e-06 28.6 1.7 4.3e-06 26.9 1.2 1.9 1 1 0 1 1 1 1 SNARE associated Golgi protein PUF PF00806.14 EDP42591.1 - 1.3e-08 33.7 3.5 0.0027 17.0 0.0 5.2 7 0 0 7 7 7 2 Pumilio-family RNA binding repeat RNase_PH PF01138.16 EDP42592.1 - 5.8e-19 68.7 0.2 1.1e-18 67.7 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 GHMP_kinases_C PF08544.8 EDP42593.1 - 2.9e-06 27.3 0.0 9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EDP42593.1 - 5.3e-06 26.3 0.3 9.9e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain ABC_tran PF00005.22 EDP42594.1 - 1.8e-45 154.6 0.0 5.8e-23 81.7 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EDP42594.1 - 5.7e-25 86.9 3.5 5.7e-25 86.9 2.4 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 EDP42594.1 - 8e-19 68.6 0.0 4.8e-06 26.7 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EDP42594.1 - 4.4e-09 35.8 0.0 0.015 14.5 0.0 4.4 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EDP42594.1 - 7.9e-09 35.7 0.0 0.0019 18.3 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EDP42594.1 - 1.5e-07 30.8 0.1 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDP42594.1 - 2.8e-07 31.3 0.3 0.11 13.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.1 EDP42594.1 - 4.6e-07 29.9 0.3 0.0095 15.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EDP42594.1 - 9.8e-07 28.7 0.1 0.026 14.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EDP42594.1 - 2.2e-06 26.9 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EDP42594.1 - 5.8e-06 26.7 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EDP42594.1 - 1.6e-05 24.6 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EDP42594.1 - 7.1e-05 23.1 0.2 1.6 9.0 0.0 3.9 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EDP42594.1 - 0.0001 22.0 0.0 0.47 10.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EDP42594.1 - 0.00011 21.4 0.2 0.24 10.3 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EDP42594.1 - 0.00016 21.5 0.2 0.062 13.2 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EDP42594.1 - 0.00024 19.9 0.0 0.15 10.7 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EDP42594.1 - 0.0005 19.5 0.0 1.3 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 EDP42594.1 - 0.00076 19.8 6.3 0.52 10.5 0.0 4.3 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 EDP42594.1 - 0.0013 18.9 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 EDP42594.1 - 0.0015 18.3 2.2 0.025 14.3 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_14 PF13173.1 EDP42594.1 - 0.0018 18.1 0.0 3.5 7.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.8 EDP42594.1 - 0.0022 16.9 0.0 0.23 10.3 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EDP42594.1 - 0.0038 17.0 5.6 0.16 11.8 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA PF00004.24 EDP42594.1 - 0.0042 17.2 0.0 1.7 8.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EDP42594.1 - 0.0079 15.6 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EDP42594.1 - 0.015 15.0 0.2 4.6 6.9 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDP42594.1 - 0.016 14.6 0.0 3.7 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDP42594.1 - 0.019 14.4 0.0 0.97 8.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EDP42594.1 - 0.025 13.4 0.0 0.097 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EDP42594.1 - 0.027 14.4 9.5 0.67 9.9 0.5 3.7 3 2 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 EDP42594.1 - 0.03 14.1 4.4 1.9 8.3 0.1 3.9 3 1 0 4 4 4 0 Dynamin family NTPase_1 PF03266.10 EDP42594.1 - 0.066 12.9 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 EDP42594.1 - 0.23 11.1 3.5 12 5.4 0.0 3.1 4 0 0 4 4 2 0 Archaeal ATPase AAA_13 PF13166.1 EDP42594.1 - 0.87 7.9 7.3 1.6 7.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain BSD PF03909.12 EDP42595.1 - 1.4e-19 69.5 0.1 1.5e-14 53.4 0.1 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EDP42595.1 - 1.1e-10 40.9 0.0 4.1e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Plasmid_RAQPRD PF09686.5 EDP42595.1 - 0.02 14.9 0.1 0.098 12.7 0.1 2.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) IL10 PF00726.12 EDP42595.1 - 0.044 13.0 0.1 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 CDC37_N PF03234.9 EDP42596.1 - 2.2e-44 151.9 7.8 4.7e-44 150.8 5.4 1.6 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EDP42596.1 - 1.9e-23 82.8 3.1 1.5e-21 76.6 0.0 2.6 3 0 0 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EDP42596.1 - 2.2e-17 62.6 0.1 1e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Cdc37 C terminal domain Blo-t-5 PF11642.3 EDP42596.1 - 0.053 13.2 0.5 0.17 11.6 0.4 1.8 1 0 0 1 1 1 0 Mite allergen Blo t 5 LSM14 PF12701.2 EDP42597.1 - 2.7e-25 88.0 0.0 4.9e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EDP42597.1 - 1.3e-07 32.0 3.3 1.3e-07 32.0 2.3 3.2 1 1 1 2 2 2 1 FDF domain SM-ATX PF14438.1 EDP42597.1 - 8.5e-05 22.4 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain AvrE PF11725.3 EDP42597.1 - 1.5 5.7 10.5 1.9 5.3 7.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Coiled-coil_56 PF09813.4 EDP42599.1 - 0.00016 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 BPL_LplA_LipB PF03099.14 EDP42600.1 - 8.6e-10 38.7 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3712 PF12505.3 EDP42601.1 - 3e-110 363.2 33.6 5.5e-24 84.5 0.2 9.5 9 0 0 9 9 9 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EDP42601.1 - 1.3e-10 41.4 1.5 0.0046 17.3 0.0 6.9 6 0 0 6 6 6 3 Late embryogenesis abundant protein Actin PF00022.14 EDP42602.1 - 0.0022 16.4 0.0 0.0024 16.3 0.0 1.0 1 0 0 1 1 1 1 Actin MU117 PF15474.1 EDP42602.1 - 0.11 13.0 0.2 0.17 12.3 0.1 1.4 1 1 0 1 1 1 0 Meiotically up-regulated gene family Actin PF00022.14 EDP42603.1 - 2.3e-29 102.0 0.0 8.7e-20 70.4 0.0 2.2 2 0 0 2 2 2 2 Actin NAD_binding_5 PF07994.7 EDP42604.1 - 1.1e-108 363.2 0.0 1.3e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EDP42604.1 - 1.7e-43 146.9 0.0 2.8e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF89 PF01937.14 EDP42605.1 - 2.1e-89 299.8 0.1 7.8e-48 163.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF89 Ala_racemase_N PF01168.15 EDP42605.1 - 7.7e-31 107.3 0.2 1.8e-23 83.2 0.0 2.3 1 1 1 2 2 2 2 Alanine racemase, N-terminal domain SBDS_C PF09377.5 EDP42606.1 - 4e-42 142.8 1.8 5.7e-42 142.3 0.8 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EDP42606.1 - 1.4e-31 108.0 1.7 1.9e-31 107.6 0.4 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Sulfate_transp PF00916.15 EDP42607.1 - 2e-45 154.9 2.8 4.6e-45 153.7 1.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EDP42607.1 - 9.3e-09 34.7 0.0 2.5e-08 33.3 0.0 1.8 1 1 1 2 2 2 1 STAS domain UCR_UQCRX_QCR9 PF05365.7 EDP42607.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4645 PF15488.1 EDP42607.1 - 0.053 12.6 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) PT-TG PF14449.1 EDP42607.1 - 0.34 10.7 3.3 0.38 10.5 0.1 2.7 4 0 0 4 4 4 0 Pre-toxin TG DUF2414 PF10309.4 EDP42608.1 - 4.5e-09 35.8 0.0 7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DEAD PF00270.24 EDP42609.1 - 8.5e-44 149.0 1.3 2.5e-43 147.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42609.1 - 3.6e-27 94.0 0.4 1.2e-26 92.3 0.3 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDP42609.1 - 2.1e-05 24.1 0.4 5.7e-05 22.7 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EDP42609.1 - 9.8e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDP42609.1 - 0.0037 16.8 0.1 0.014 14.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.20 EDP42609.1 - 0.013 14.6 0.2 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 EDP42609.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EDP42609.1 - 0.061 13.0 0.2 0.28 10.9 0.0 2.2 3 0 0 3 3 3 0 Flavivirus DEAD domain Fanconi_A PF03511.9 EDP42609.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein CMS1 PF14617.1 EDP42609.1 - 0.082 11.9 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SLAC1 PF03595.12 EDP42610.1 - 1.1e-47 162.3 22.7 1.2e-47 162.1 15.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PMT PF02366.13 EDP42611.1 - 5.3e-72 242.1 18.3 5.3e-72 242.1 12.7 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDP42611.1 - 8.8e-19 67.7 0.0 2.2e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 MIR domain Peptidase_M15 PF01427.12 EDP42611.1 - 0.08 12.5 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase WD40 PF00400.27 EDP42612.1 - 4e-55 181.8 14.1 5.2e-14 51.4 0.6 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EDP42612.1 - 9.4e-05 22.2 0.4 0.87 9.2 0.0 4.0 1 1 4 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDP42612.1 - 0.00028 19.1 7.2 0.52 8.3 0.0 4.0 2 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 EDP42612.1 - 0.00031 19.1 0.0 0.00077 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 EDP42612.1 - 0.0072 15.1 0.0 0.014 14.2 0.0 1.3 1 1 0 1 1 1 1 Coatomer WD associated region dsrm PF00035.20 EDP42613.1 - 1.8e-08 34.8 0.0 3.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EDP42613.1 - 7.1e-05 23.2 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EDP42613.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like PHTB1_C PF14728.1 EDP42613.1 - 0.056 12.2 0.1 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus UDG PF03167.14 EDP42613.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily SRP54 PF00448.17 EDP42614.1 - 3.3e-34 118.0 0.0 1.3e-32 112.8 0.0 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EDP42614.1 - 1.6e-24 86.8 8.7 4.7e-24 85.2 6.0 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 EDP42614.1 - 1.4e-06 27.8 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EDP42614.1 - 9.3e-06 25.6 0.0 3.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EDP42614.1 - 1.5e-05 23.9 0.0 3.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EDP42614.1 - 0.0029 17.3 0.0 0.0096 15.6 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDP42614.1 - 0.0086 16.2 0.0 0.075 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDP42614.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain VirC1 PF07015.6 EDP42614.1 - 0.12 11.4 0.2 35 3.3 0.0 3.1 3 0 0 3 3 3 0 VirC1 protein Fer4_NifH PF00142.13 EDP42614.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Na_H_Exchanger PF00999.16 EDP42615.1 - 5.8e-63 212.6 38.0 7.2e-63 212.3 26.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PDR_CDR PF06422.7 EDP42615.1 - 0.2 11.3 0.9 0.9 9.2 0.6 2.1 1 0 0 1 1 1 0 CDR ABC transporter Abhydrolase_6 PF12697.2 EDP42616.1 - 5.2e-07 29.7 0.0 1.4e-06 28.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDP42616.1 - 0.00018 21.3 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EDP42616.1 - 0.00044 19.8 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP42616.1 - 0.005 16.6 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family SWIRM PF04433.12 EDP42617.1 - 1.1e-34 118.4 0.1 2.4e-34 117.2 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EDP42617.1 - 6.6e-08 31.9 1.0 1.3e-07 31.0 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EDP42617.1 - 1.9e-07 31.0 0.5 4.1e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP42617.1 - 7.7e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF904 PF06005.7 EDP42617.1 - 0.57 10.5 7.2 1.4 9.2 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) RhoGAP PF00620.22 EDP42618.1 - 2.3e-39 134.4 0.0 5.2e-39 133.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 EDP42618.1 - 5.5e-09 36.0 0.0 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDP42618.1 - 1.4e-07 31.5 0.0 4.5e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Cellulase PF00150.13 EDP42619.1 - 6.2e-18 64.9 7.8 1.3e-17 63.9 5.4 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SelP_N PF04592.9 EDP42619.1 - 7.7 5.8 23.6 15 4.8 16.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPR_16 PF13432.1 EDP42622.1 - 1.8e-10 41.1 12.2 0.017 15.7 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42622.1 - 8.2e-09 35.2 10.2 0.42 10.5 0.3 7.2 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42622.1 - 1.2e-08 34.7 20.9 7.8 7.4 0.0 11.4 10 2 3 13 13 12 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EDP42622.1 - 1.3e-08 34.1 4.5 0.0025 16.7 0.0 5.5 4 1 2 6 6 6 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 EDP42622.1 - 1.4e-07 31.7 4.0 5.8 7.3 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDP42622.1 - 1.5e-06 27.7 12.0 3.5 7.3 0.0 7.6 6 1 4 10 10 10 3 TPR repeat TPR_2 PF07719.12 EDP42622.1 - 1.7e-06 27.4 15.7 0.83 9.7 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EDP42622.1 - 8.1e-06 25.6 6.9 0.33 10.7 0.2 6.4 7 1 1 8 8 8 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 EDP42622.1 - 0.00083 19.3 9.6 17 5.9 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR_3 PF13812.1 EDP42622.1 - 0.0059 16.7 0.1 0.12 12.6 0.0 3.4 3 0 0 3 3 2 1 Pentatricopeptide repeat domain TPR_1 PF00515.23 EDP42622.1 - 0.0093 15.5 5.5 27 4.5 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP42622.1 - 0.18 11.9 4.5 20 5.4 0.1 4.7 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDP42622.1 - 0.22 12.0 8.3 1.2e+02 3.5 0.0 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat UCH PF00443.24 EDP42623.1 - 5e-46 156.9 0.0 7.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP42623.1 - 2.6e-16 59.9 0.0 7.8e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase R3H PF01424.17 EDP42624.1 - 2e-11 43.3 0.4 5.2e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 EDP42624.1 - 9.7e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP42624.1 - 4.3e-07 29.4 0.0 8.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42624.1 - 3e-05 23.7 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDP42625.1 - 2.5e-44 147.5 4.1 2.2e-09 36.8 0.3 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 EDP42625.1 - 0.087 13.1 0.0 0.087 13.1 0.0 2.4 3 0 0 3 3 3 0 Striatin family Med26 PF08711.6 EDP42627.1 - 4.1e-08 32.6 0.0 7.1e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_S4 PF00163.14 EDP42628.1 - 1.8e-29 101.9 0.7 3.4e-29 101.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDP42628.1 - 1.7e-13 49.7 0.4 1.7e-13 49.7 0.3 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EDP42629.1 - 1.8e-30 104.6 3.6 2.7e-30 104.0 2.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF1989 PF09347.5 EDP42629.1 - 0.053 12.9 0.0 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1989) RNA_replicase_B PF03431.8 EDP42629.1 - 0.066 11.4 0.2 0.078 11.1 0.1 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain PUA PF01472.15 EDP42629.1 - 0.23 11.2 1.8 0.56 9.9 0.4 2.2 2 1 0 2 2 2 0 PUA domain Amidohydro_4 PF13147.1 EDP42630.1 - 4.6e-06 26.8 0.4 4.6e-06 26.8 0.3 3.1 3 2 1 4 4 4 1 Amidohydrolase Amidohydro_1 PF01979.15 EDP42630.1 - 1.4e-05 24.9 0.0 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EDP42630.1 - 0.027 14.2 0.1 0.099 12.4 0.1 2.1 1 1 0 1 1 1 0 Amidohydrolase Ank_2 PF12796.2 EDP42631.1 - 1.1e-18 67.3 3.9 2.6e-12 46.8 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP42631.1 - 1.3e-14 54.2 3.8 8.7e-10 38.8 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EDP42631.1 - 2.2e-14 52.4 0.4 6.6e-07 28.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDP42631.1 - 7.7e-12 45.0 2.0 7.2e-06 26.0 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP42631.1 - 2.4e-11 42.7 0.1 0.00016 21.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Sds3 PF08598.6 EDP42632.1 - 8.5e-22 77.6 2.1 6.1e-21 74.8 0.0 2.6 2 0 0 2 2 2 1 Sds3-like BCDHK_Adom3 PF10436.4 EDP42633.1 - 9.9e-62 207.2 0.0 1.5e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDP42633.1 - 6.9e-16 57.9 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDP42633.1 - 8.1e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mt_ATP-synt_B PF05405.9 EDP42634.1 - 2.3e-43 147.4 2.6 2.9e-43 147.1 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.20 EDP42635.1 - 4e-70 235.9 0.0 4.7e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42635.1 - 2.5e-32 111.9 0.0 4e-32 111.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase VPS9 PF02204.13 EDP42636.1 - 3.5e-30 104.1 0.0 6.1e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EDP42636.1 - 2.1e-10 39.8 0.1 4.7e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 EDP42636.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif RRM_6 PF14259.1 EDP42637.1 - 2e-08 34.1 0.0 0.00075 19.4 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP42637.1 - 2.6e-07 30.1 0.0 0.0084 15.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_CoA_synt_N PF01154.12 EDP42638.1 - 2.2e-86 287.8 0.1 3.1e-86 287.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EDP42638.1 - 9.5e-76 254.9 0.2 1.4e-75 254.4 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 EDP42638.1 - 0.0073 16.2 0.2 0.08 12.9 0.1 2.4 1 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AAA PF00004.24 EDP42640.1 - 1.3e-83 277.7 0.0 2.2e-41 141.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP42640.1 - 2.1e-13 50.6 0.9 1.9e-07 31.2 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EDP42640.1 - 1.7e-11 43.6 0.0 1.4e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDP42640.1 - 2.4e-11 43.8 0.6 3.2e-05 24.0 0.1 4.4 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EDP42640.1 - 6.5e-11 42.1 0.2 1.7e-05 24.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDP42640.1 - 8e-07 29.0 0.0 0.0005 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP42640.1 - 1.1e-06 28.5 0.0 0.0025 17.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EDP42640.1 - 1.7e-06 28.1 0.0 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.1 EDP42640.1 - 2e-06 28.6 0.0 0.0096 16.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDP42640.1 - 2.7e-06 26.3 0.0 0.011 14.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 EDP42640.1 - 6.9e-06 26.0 0.0 0.015 15.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EDP42640.1 - 9.1e-06 25.3 0.4 0.013 15.2 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 EDP42640.1 - 1.5e-05 24.2 0.0 0.0026 16.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EDP42640.1 - 2.3e-05 24.0 0.0 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP42640.1 - 3.7e-05 23.4 0.0 0.096 12.3 0.0 3.7 3 1 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.12 EDP42640.1 - 7.8e-05 22.1 0.0 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EDP42640.1 - 0.00013 21.9 0.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDP42640.1 - 0.00014 21.1 0.1 0.068 12.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDP42640.1 - 0.00021 20.9 0.0 0.24 11.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDP42640.1 - 0.00056 19.6 0.0 0.97 9.0 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EDP42640.1 - 0.00057 19.3 5.2 0.051 12.9 0.3 4.0 2 2 1 3 3 3 1 AAA domain Rad17 PF03215.10 EDP42640.1 - 0.0006 18.6 0.0 0.056 12.1 0.0 2.4 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 EDP42640.1 - 0.00067 19.7 0.0 0.22 11.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EDP42640.1 - 0.0034 17.6 0.0 0.087 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDP42640.1 - 0.0051 16.4 0.0 0.27 10.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EDP42640.1 - 0.01 16.1 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.13 EDP42640.1 - 0.03 13.8 0.0 0.63 9.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EDP42640.1 - 0.036 12.9 0.0 0.61 8.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) KaiC PF06745.8 EDP42640.1 - 0.046 12.8 0.1 2.3 7.2 0.0 2.8 3 0 0 3 3 3 0 KaiC UPF0079 PF02367.12 EDP42640.1 - 0.049 13.2 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EDP42640.1 - 0.053 12.9 0.0 5 6.5 0.0 3.6 3 1 1 4 4 4 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EDP42640.1 - 0.14 11.8 0.1 2 8.1 0.0 2.8 3 1 1 4 4 3 0 NTPase PhoH PF02562.11 EDP42640.1 - 0.14 11.3 1.8 0.33 10.1 0.0 2.5 4 0 0 4 4 2 0 PhoH-like protein NB-ARC PF00931.17 EDP42640.1 - 0.23 10.3 0.0 4.6 5.9 0.0 2.8 2 1 1 3 3 3 0 NB-ARC domain FAD_binding_3 PF01494.14 EDP42641.1 - 6.3e-19 68.2 0.4 1.6e-08 34.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EDP42641.1 - 0.0028 16.5 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Hpt PF01627.18 EDP42641.1 - 0.011 15.6 0.4 0.034 14.1 0.3 1.8 1 0 0 1 1 1 0 Hpt domain MMS19_N PF14500.1 EDP42642.1 - 4.5e-65 219.5 0.1 2.1e-52 177.9 0.0 4.5 5 0 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EDP42642.1 - 1.7e-41 142.2 3.9 4.7e-41 140.8 0.0 3.5 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 EDP42642.1 - 0.012 15.5 3.6 6 6.8 0.0 4.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF1314 PF07013.6 EDP42642.1 - 0.022 14.1 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) HEAT PF02985.17 EDP42642.1 - 1.6 8.9 20.6 0.48 10.6 0.1 6.8 6 1 1 7 7 7 0 HEAT repeat zf-CCCH PF00642.19 EDP42643.1 - 3.3e-13 48.9 18.1 1.9e-08 33.7 1.0 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDP42643.1 - 3.5 7.7 21.8 1.2 9.2 0.2 4.7 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Rtf2 PF04641.7 EDP42644.1 - 5.1e-32 111.0 0.1 4.5e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger S1 PF00575.18 EDP42645.1 - 4.6e-11 42.6 0.1 1.1e-10 41.4 0.1 1.6 1 1 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 EDP42645.1 - 1.6e-10 40.9 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EDP42645.1 - 0.032 14.4 0.0 0.06 13.5 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Pkinase PF00069.20 EDP42647.1 - 4e-33 114.6 0.0 5.3e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42647.1 - 3.2e-13 49.3 0.0 4.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42647.1 - 4.6e-05 22.5 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42647.1 - 0.0034 17.1 0.2 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDP42647.1 - 0.0086 15.4 0.0 0.035 13.4 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EDP42647.1 - 0.044 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_transf_20 PF00982.16 EDP42648.1 - 3.5e-150 500.5 0.0 4.9e-150 500.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDP42648.1 - 4.1e-16 58.6 0.0 9.5e-16 57.4 0.0 1.5 1 1 0 1 1 1 1 Trehalose-phosphatase CEP1-DNA_bind PF09287.5 EDP42648.1 - 0.0034 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 CEP-1, DNA binding P16-Arc PF04699.9 EDP42649.1 - 4.1e-47 160.0 0.0 4.5e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) SpaB_C PF14028.1 EDP42649.1 - 0.029 13.9 1.7 0.035 13.6 1.2 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Pkinase PF00069.20 EDP42650.1 - 1.3e-73 247.3 0.1 2.3e-73 246.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42650.1 - 6.1e-53 179.5 0.1 1.1e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDP42650.1 - 1.6e-21 76.4 0.0 5.1e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EDP42650.1 - 6.9e-10 39.0 0.6 1.6e-09 37.8 0.4 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EDP42650.1 - 5.2e-07 28.9 0.0 9e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EDP42650.1 - 2.4e-05 24.5 1.0 0.077 13.2 0.2 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain APH PF01636.18 EDP42650.1 - 0.023 14.4 0.1 0.023 14.4 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family PH_9 PF15410.1 EDP42650.1 - 0.097 12.8 0.6 5.8 7.0 0.4 2.7 1 1 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.17 EDP42651.1 - 4e-22 77.6 0.0 8.6e-14 50.9 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42651.1 - 2.6e-16 59.3 0.0 1.1e-07 31.7 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42651.1 - 1.9e-09 37.2 0.0 0.092 12.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FF PF01846.14 EDP42652.1 - 2e-28 98.0 2.6 4.1e-11 42.6 0.0 5.7 5 0 0 5 5 5 5 FF domain WW PF00397.21 EDP42652.1 - 7.3e-05 22.5 4.6 7.3e-05 22.5 3.2 2.2 2 0 0 2 2 2 1 WW domain HSP70 PF00012.15 EDP42653.1 - 8.6e-73 245.2 0.0 1.4e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDP42653.1 - 2e-06 26.6 0.0 0.0005 18.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EDP42653.1 - 0.018 13.9 0.1 0.075 11.9 0.1 1.8 1 1 0 1 1 1 0 Type IV pilus assembly protein PilM; Guanylate_kin PF00625.16 EDP42654.1 - 8.1e-56 188.3 0.0 9.4e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EDP42654.1 - 7.9e-07 29.0 0.0 3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDP42654.1 - 3.5e-06 27.1 0.2 2.7e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDP42654.1 - 3.9e-06 27.0 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDP42654.1 - 4.7e-06 25.8 0.0 7.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EDP42654.1 - 0.00011 22.5 0.0 0.00043 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP42654.1 - 0.00013 22.7 0.0 0.00035 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDP42654.1 - 0.00062 19.5 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EDP42654.1 - 0.00072 19.7 0.0 0.0018 18.4 0.0 1.7 2 0 0 2 2 1 1 RNA helicase MMR_HSR1 PF01926.18 EDP42654.1 - 0.00087 19.2 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EDP42654.1 - 0.00094 19.4 0.0 0.0016 18.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EDP42654.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EDP42654.1 - 0.0014 18.6 0.0 0.043 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDP42654.1 - 0.0037 17.1 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDP42654.1 - 0.005 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDP42654.1 - 0.005 17.0 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EDP42654.1 - 0.0051 16.3 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EDP42654.1 - 0.0058 16.3 0.0 0.052 13.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EDP42654.1 - 0.0065 15.9 0.0 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Rad17 PF03215.10 EDP42654.1 - 0.011 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Septin PF00735.13 EDP42654.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.10 EDP42654.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 EDP42654.1 - 0.041 13.0 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDP42654.1 - 0.045 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EDP42654.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4485 PF14846.1 EDP42654.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF815 PF05673.8 EDP42654.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EDP42654.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 EDP42654.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Histone PF00125.19 EDP42655.1 - 4.9e-13 48.9 0.1 6.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDP42655.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EDP42655.1 - 0.00058 19.7 0.1 0.00083 19.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EDP42655.1 - 0.00076 19.4 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Nup35_RRM PF05172.8 EDP42656.1 - 2.2e-09 36.9 0.0 4.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EDP42656.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EDP42657.1 - 1.3e-71 240.8 0.0 1.5e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42657.1 - 2.2e-32 112.1 0.0 2.7e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42657.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP42657.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDP42657.1 - 0.0092 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EDP42657.1 - 0.035 13.1 0.1 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.14 EDP42658.1 - 1.3e-18 67.2 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DNA_pol_viral_N PF00242.12 EDP42659.1 - 1.3 8.0 12.9 0.54 9.2 7.2 1.6 1 1 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HAD_2 PF13419.1 EDP42660.1 - 3.5e-13 50.1 0.0 4.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDP42660.1 - 6.8e-07 29.9 0.0 1.3e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EDP42660.1 - 0.0015 18.4 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP42660.1 - 0.022 14.9 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EDP42660.1 - 0.032 13.7 0.2 8.1 5.9 0.0 2.8 3 0 0 3 3 3 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Snf7 PF03357.16 EDP42661.1 - 2.3e-41 141.0 19.7 2.9e-41 140.6 13.7 1.0 1 0 0 1 1 1 1 Snf7 Imm43 PF15602.1 EDP42661.1 - 0.023 14.6 0.9 0.031 14.2 0.6 1.3 1 0 0 1 1 1 0 Immunity protein 43 Glutaredoxin PF00462.19 EDP42661.1 - 0.051 13.5 0.1 0.22 11.5 0.1 2.1 1 0 0 1 1 1 0 Glutaredoxin Transpep_BrtH PF14399.1 EDP42661.1 - 0.15 11.3 1.9 0.2 10.8 1.3 1.3 1 1 0 1 1 1 0 NlpC/p60-like transpeptidase Exonuc_VII_L PF02601.10 EDP42661.1 - 0.21 10.7 9.3 0.28 10.3 6.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.7 EDP42661.1 - 0.25 11.6 8.6 0.27 11.5 2.0 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF885 PF05960.6 EDP42661.1 - 0.38 9.8 7.7 0.45 9.6 5.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Herpes_UL14 PF03580.9 EDP42661.1 - 0.6 9.9 10.6 0.3 10.8 5.2 1.9 1 1 1 2 2 2 0 Herpesvirus UL14-like protein Mod_r PF07200.8 EDP42661.1 - 0.97 9.3 12.4 9.6 6.1 7.9 2.5 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GrpE PF01025.14 EDP42661.1 - 1.5 8.3 13.1 0.64 9.5 4.2 2.7 1 1 1 2 2 2 0 GrpE Phage_GP20 PF06810.6 EDP42661.1 - 2.1 7.7 13.8 2 7.8 6.0 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 HrpB7 PF09486.5 EDP42661.1 - 2.4 8.0 13.0 0.053 13.4 1.0 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF342 PF03961.8 EDP42661.1 - 2.6 6.3 10.2 4.1 5.6 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF848 PF05852.6 EDP42661.1 - 4 7.2 10.6 3.1 7.6 5.6 2.0 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Atg14 PF10186.4 EDP42661.1 - 4.5 6.1 12.0 7.8 5.3 8.3 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 EDP42661.1 - 9.1 6.5 12.9 0.69 10.1 0.9 3.0 1 1 1 2 2 2 0 Syntaxin BAR PF03114.13 EDP42662.1 - 3.6e-45 154.2 0.1 4.7e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 BAR domain DUF826 PF05696.6 EDP42662.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Metallophos PF00149.23 EDP42663.1 - 6.3e-27 94.2 0.0 2e-26 92.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EDP42663.1 - 1.4e-22 79.1 4.1 1.2e-14 53.6 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDP42663.1 - 1.9e-18 65.2 1.3 3.5e-05 23.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDP42663.1 - 8.5e-14 50.2 1.0 0.00092 18.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 EDP42663.1 - 4.1e-10 39.5 0.0 3.8e-07 30.0 0.0 2.5 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_16 PF13432.1 EDP42663.1 - 7.6e-07 29.6 1.2 0.00015 22.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDP42663.1 - 1.8e-06 27.6 1.8 0.016 15.3 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP42663.1 - 1.9e-05 24.0 0.1 0.64 9.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42663.1 - 6.8e-05 23.1 1.9 0.86 10.4 0.1 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42663.1 - 0.00015 21.5 1.9 0.00066 19.5 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP42663.1 - 0.00052 20.2 4.4 0.47 10.8 1.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP42663.1 - 0.0021 17.8 0.5 0.036 13.9 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP42663.1 - 0.017 15.5 1.7 10 6.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L21p PF00829.16 EDP42664.1 - 6.1e-09 35.9 0.0 2.1e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 EDP42665.1 - 5.8e-69 231.8 0.0 8.6e-69 231.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDP42665.1 - 1.5e-23 83.4 0.0 4.4e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDP42665.1 - 9.6e-20 70.5 1.4 3.2e-19 68.8 0.9 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDP42665.1 - 6.1e-06 26.0 1.5 1.3e-05 24.9 1.1 1.6 1 0 0 1 1 1 1 HAS barrel domain FmdE PF02663.9 EDP42665.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon AAA_25 PF13481.1 EDP42665.1 - 0.048 13.0 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_M PF01031.15 EDP42666.1 - 8.3e-109 362.9 0.0 1.4e-108 362.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDP42666.1 - 4.7e-34 117.6 0.0 1.1e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EDP42666.1 - 1.4e-27 95.4 3.1 4e-27 93.9 2.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Sas10_Utp3 PF04000.10 EDP42667.1 - 1.1e-09 38.3 0.6 2.2e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MBOAT PF03062.14 EDP42668.1 - 3.7e-34 118.2 20.6 1.2e-33 116.5 14.3 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EDP42668.1 - 0.022 14.8 3.1 0.022 14.8 2.1 1.9 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family DUF4658 PF15555.1 EDP42668.1 - 0.15 11.9 1.0 0.27 11.1 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) UAA PF08449.6 EDP42669.1 - 3.4e-76 256.0 15.0 3.9e-76 255.8 10.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDP42669.1 - 5.4e-05 22.8 3.8 5.4e-05 22.8 2.6 2.6 2 1 1 3 3 3 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EDP42669.1 - 6.2e-05 22.2 0.2 0.00013 21.1 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF4231 PF14015.1 EDP42669.1 - 0.072 13.0 0.2 0.072 13.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) 7TMR-DISM_7TM PF07695.6 EDP42669.1 - 4.1 7.0 26.4 0.13 11.8 9.2 2.4 1 1 1 2 2 2 0 7TM diverse intracellular signalling RasGEF PF00617.14 EDP42671.1 - 2e-41 141.7 0.2 3.8e-41 140.8 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDP42671.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SRF-TF PF00319.13 EDP42672.1 - 8.2e-19 66.5 0.0 1.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BNR PF02012.15 EDP42673.1 - 5e-08 31.6 36.6 1.6 8.8 0.4 11.2 11 0 0 11 11 11 6 BNR/Asp-box repeat PSII_BNR PF14870.1 EDP42673.1 - 0.0033 16.4 0.3 0.76 8.7 0.1 3.9 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C_1 PF13290.1 EDP42673.1 - 0.044 13.5 0.6 29 4.5 0.0 3.7 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF3674 PF12426.3 EDP42674.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF2721 PF11026.3 EDP42674.1 - 5.2 6.7 6.8 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Dus PF01207.12 EDP42675.1 - 2.8e-39 134.7 0.0 1.8e-27 95.9 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ASF1_hist_chap PF04729.8 EDP42676.1 - 1.5e-67 226.0 0.1 2.1e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Sterol_MT_C PF08498.5 EDP42677.1 - 4e-30 103.5 0.2 5.8e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EDP42677.1 - 7.1e-18 64.8 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42677.1 - 2.7e-17 62.7 0.0 3.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP42677.1 - 4.9e-16 58.8 0.0 7.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP42677.1 - 1.4e-14 54.5 0.0 8e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EDP42677.1 - 1.1e-13 50.8 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EDP42677.1 - 1.7e-11 44.3 0.0 4.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP42677.1 - 2.9e-11 43.7 0.1 8.7e-11 42.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP42677.1 - 7.3e-11 42.1 0.0 2e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDP42677.1 - 1.4e-06 27.6 0.0 3.2e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDP42677.1 - 2e-05 24.0 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EDP42677.1 - 2.4e-05 23.9 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EDP42677.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 EDP42677.1 - 0.00036 19.6 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 EDP42677.1 - 0.0031 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EDP42677.1 - 0.0034 17.0 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EDP42677.1 - 0.018 15.8 0.0 0.096 13.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 EDP42677.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EDP42677.1 - 0.042 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EDP42677.1 - 0.048 12.8 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EDP42677.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DHO_dh PF01180.16 EDP42678.1 - 2.3e-98 328.8 0.0 3.1e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EDP42678.1 - 0.0014 17.5 0.3 0.026 13.3 0.4 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EDP42678.1 - 0.0023 17.1 0.2 0.0046 16.1 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase zf-H2C2_2 PF13465.1 EDP42679.1 - 5.7e-25 86.3 18.4 5.4e-07 29.5 0.1 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EDP42679.1 - 4.5e-22 77.0 23.0 2.5e-05 24.3 1.3 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP42679.1 - 6.3e-15 54.3 20.8 0.00049 20.2 0.5 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDP42679.1 - 5.5e-07 29.5 7.2 0.0076 16.3 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDP42679.1 - 0.00014 21.9 11.2 0.018 15.2 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDP42679.1 - 0.00088 19.0 11.7 0.016 15.0 0.4 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 EDP42679.1 - 0.024 14.9 9.1 0.14 12.5 0.9 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger Viral_helicase1 PF01443.13 EDP42679.1 - 0.069 12.6 0.1 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ogr_Delta PF04606.7 EDP42679.1 - 1 9.0 4.1 12 5.6 0.1 2.7 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger SMC_N PF02463.14 EDP42680.1 - 2.2e-73 246.1 0.0 3.6e-73 245.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDP42680.1 - 1.9e-27 95.6 0.0 6.5e-27 93.8 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDP42680.1 - 2.1e-16 60.7 0.9 4.2e-07 30.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDP42680.1 - 6e-11 43.0 0.0 6e-11 43.0 0.0 5.5 4 1 0 4 4 4 1 AAA domain AAA_15 PF13175.1 EDP42680.1 - 4e-06 26.1 0.0 0.0035 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDP42680.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain 7tm_6 PF02949.15 EDP42680.1 - 0.067 12.0 0.6 0.19 10.5 0.4 1.7 1 0 0 1 1 1 0 7tm Odorant receptor ABC_tran PF00005.22 EDP42680.1 - 0.25 11.6 0.0 0.25 11.6 0.0 4.9 4 2 1 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 EDP42680.1 - 1.6 7.8 33.6 0.089 11.9 2.5 5.1 3 2 4 7 7 7 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EDP42680.1 - 1.8 8.3 17.2 0.046 13.5 1.7 4.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ipi1_N PF12333.3 EDP42681.1 - 0.077 12.9 0.1 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation DUF2418 PF10332.4 EDP42682.1 - 1e-13 51.3 0.0 1.1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Racemase_4 PF13615.1 EDP42683.1 - 5.6e-21 74.7 0.0 1.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Putative alanine racemase MCM PF00493.18 EDP42683.1 - 0.012 14.4 0.0 0.055 12.2 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family CKS PF01111.14 EDP42684.1 - 1.9e-34 117.2 0.3 2.8e-34 116.7 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Aldo_ket_red PF00248.16 EDP42685.1 - 2e-52 177.7 0.0 2.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Molydop_binding PF01568.16 EDP42685.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Aldo_ket_red PF00248.16 EDP42686.1 - 1.7e-52 178.0 0.0 2.2e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Viral_DNA_bp PF00747.12 EDP42686.1 - 0.023 11.9 0.0 0.029 11.6 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein Aldo_ket_red PF00248.16 EDP42687.1 - 2.8e-52 177.3 0.0 3.6e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Viral_DNA_bp PF00747.12 EDP42687.1 - 0.062 10.5 0.0 0.079 10.1 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein DUF2194 PF09960.4 EDP42687.1 - 0.097 10.7 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) tRNA-synt_2b PF00587.20 EDP42688.1 - 9.2e-65 217.4 0.0 1.6e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP42688.1 - 7.8e-21 73.8 0.0 1.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Mcp5_PH PF12814.2 EDP42690.1 - 9.6e-37 125.6 0.0 3e-36 124.0 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SF-assemblin PF06705.6 EDP42690.1 - 0.0052 15.9 14.3 0.0052 15.9 9.9 3.3 1 1 2 3 3 3 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EDP42690.1 - 7 6.4 17.6 0.46 10.3 1.4 3.7 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nop10p PF04135.7 EDP42691.1 - 1.3e-19 69.6 0.2 1.5e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family EMP24_GP25L PF01105.19 EDP42692.1 - 3.9e-32 111.4 0.0 4.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Integrin_alpha PF00357.15 EDP42692.1 - 0.42 10.5 1.8 0.89 9.5 1.2 1.5 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region zf-UBR PF02207.15 EDP42693.1 - 1e-12 47.5 8.3 1e-12 47.5 5.8 3.8 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EDP42693.1 - 0.00016 21.2 8.5 0.00016 21.2 5.9 3.5 3 2 0 3 3 3 1 PHD-finger Pyrid_oxidase_2 PF13883.1 EDP42694.1 - 6.5e-19 68.3 0.1 8.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VRR_NUC PF08774.6 EDP42695.1 - 8.4e-15 54.6 0.0 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain SAP PF02037.22 EDP42695.1 - 0.00064 19.1 0.8 0.0014 18.0 0.5 1.6 1 0 0 1 1 1 1 SAP domain Myosin_head PF00063.16 EDP42697.1 - 2.1e-244 812.7 0.0 2.1e-244 812.7 0.0 2.2 2 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 EDP42697.1 - 0.001 18.7 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EDP42697.1 - 0.026 14.2 0.0 0.15 11.8 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain Myosin_tail_1 PF01576.14 EDP42697.1 - 0.045 11.4 108.2 0.0071 14.1 51.0 2.9 1 1 2 3 3 3 0 Myosin tail AAA_22 PF13401.1 EDP42697.1 - 0.33 11.1 0.0 0.33 11.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain MOZ_SAS PF01853.13 EDP42698.1 - 4.8e-15 55.2 0.0 6.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family WD40 PF00400.27 EDP42699.1 - 9.2e-83 269.4 23.3 2.2e-13 49.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDP42699.1 - 5.9e-14 51.1 7.5 8e-05 20.9 0.2 4.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP42699.1 - 3.8e-05 22.6 2.2 1.1 7.9 0.0 3.9 1 1 2 3 3 3 3 Nup133 N terminal like IKI3 PF04762.7 EDP42699.1 - 0.046 11.5 0.0 1.8 6.3 0.0 2.1 1 1 1 2 2 2 0 IKI3 family DUF1652 PF07865.6 EDP42699.1 - 0.098 12.2 0.0 9.9 5.8 0.0 3.8 4 1 0 5 5 5 0 Protein of unknown function (DUF1652) Kinesin PF00225.18 EDP42700.1 - 3.7e-77 259.2 1.5 8.7e-43 146.2 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Snapin_Pallidin PF14712.1 EDP42700.1 - 0.021 15.1 0.8 0.021 15.1 0.5 3.0 3 1 0 3 3 3 0 Snapin/Pallidin DUF4407 PF14362.1 EDP42700.1 - 0.11 11.4 3.8 0.18 10.7 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 EDP42700.1 - 0.13 12.0 16.7 0.095 12.5 5.5 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EDP42700.1 - 0.32 11.2 3.1 18 5.6 0.1 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EDP42700.1 - 1.3 8.8 10.4 0.42 10.4 1.5 2.7 1 1 1 2 2 2 0 Tropomyosin like Tropomyosin PF00261.15 EDP42700.1 - 1.9 7.5 12.5 0.86 8.6 6.6 1.8 1 1 1 2 2 2 0 Tropomyosin DUF16 PF01519.11 EDP42700.1 - 7.2 6.8 6.4 2 8.6 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 EDP42700.1 - 9.4 6.0 19.7 14 5.5 1.8 4.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DAHP_synth_1 PF00793.15 EDP42701.1 - 4.2e-88 294.5 0.0 5e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 EDP42701.1 - 0.048 13.3 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 SRX CBFD_NFYB_HMF PF00808.18 EDP42702.1 - 1.2e-18 66.8 0.1 2.1e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1127 PF06568.6 EDP42702.1 - 0.08 12.3 0.8 0.18 11.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) FTHFS PF01268.14 EDP42703.1 - 6.6e-256 849.6 0.0 5.1e-255 846.7 0.0 1.9 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EDP42703.1 - 3.9e-61 204.8 3.1 1.1e-60 203.3 1.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EDP42703.1 - 8.1e-18 64.5 1.1 1.7e-17 63.5 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IL4 PF00727.13 EDP42703.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin 4 SAM_2 PF07647.12 EDP42704.1 - 2.3e-09 36.9 1.0 4.5e-09 36.0 0.0 2.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDP42704.1 - 3.2e-06 27.2 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2668 PF10873.3 EDP42705.1 - 0.098 12.8 0.3 0.098 12.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) ATP-synt_ab PF00006.20 EDP42706.1 - 4.5e-64 215.8 0.0 7.3e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDP42706.1 - 4.2e-24 85.1 0.7 7.3e-24 84.4 0.5 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDP42706.1 - 6.5e-15 55.1 0.8 2.4e-14 53.2 0.5 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.1 EDP42706.1 - 0.0071 16.3 0.4 0.023 14.6 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EDP42706.1 - 0.011 15.0 0.1 0.026 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EDP42706.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDP42706.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDP42706.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.6 1 1 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EDP42706.1 - 0.016 14.3 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EDP42706.1 - 0.016 14.8 0.3 0.76 9.4 0.1 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EDP42706.1 - 0.028 13.5 0.3 0.053 12.6 0.2 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EDP42706.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDP42706.1 - 0.047 12.5 1.0 0.071 11.9 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EDP42706.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EDP42706.1 - 0.13 12.2 0.1 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EDP42707.1 - 3.1e-82 275.7 3.0 2e-69 233.7 0.3 2.0 1 1 1 2 2 2 2 Septin AAA_22 PF13401.1 EDP42707.1 - 7.1e-05 22.9 0.2 0.0066 16.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDP42707.1 - 0.00017 21.5 0.5 0.00065 19.6 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDP42707.1 - 0.00031 19.9 0.1 0.00053 19.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EDP42707.1 - 0.00064 19.2 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EDP42707.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EDP42707.1 - 0.0069 16.2 0.1 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EDP42707.1 - 0.0069 15.5 0.3 0.0069 15.5 0.2 2.1 3 0 0 3 3 3 1 AIG1 family Miro PF08477.8 EDP42707.1 - 0.0073 16.8 0.1 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EDP42707.1 - 0.0086 15.5 0.5 0.017 14.6 0.3 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EDP42707.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.8 EDP42707.1 - 0.015 14.1 0.3 0.036 12.8 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 EDP42707.1 - 0.023 13.5 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EDP42707.1 - 0.039 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 EDP42707.1 - 0.057 12.0 1.4 0.067 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EDP42707.1 - 0.068 12.2 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDP42707.1 - 0.14 12.0 0.7 1.6 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain SCAMP PF04144.8 EDP42708.1 - 6.1e-43 146.7 11.0 7.3e-43 146.4 7.6 1.1 1 0 0 1 1 1 1 SCAMP family DUF3563 PF12086.3 EDP42708.1 - 0.15 11.8 3.6 0.34 10.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Bromodomain PF00439.20 EDP42709.1 - 3.6e-40 135.7 1.4 5.1e-19 67.9 0.0 2.4 2 0 0 2 2 2 2 Bromodomain CENP-S PF15630.1 EDP42709.1 - 0.03 14.5 0.5 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Kinetochore component CENP-S Sec39 PF08314.6 EDP42710.1 - 1.2e-24 86.2 0.0 1.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF3419 PF11899.3 EDP42711.1 - 7.5e-138 459.3 0.0 1.1e-137 458.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EDP42711.1 - 1.9e-08 34.2 0.0 1.3e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42711.1 - 2.7e-08 33.5 0.0 7.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDP42711.1 - 1.9e-06 27.1 0.0 1.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EDP42711.1 - 2.1e-06 28.0 0.0 7.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP42711.1 - 2.6e-06 27.8 0.0 0.00011 22.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP42711.1 - 0.00016 22.2 0.0 0.00054 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP42711.1 - 0.0003 21.1 0.0 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDP42711.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Adaptin_N PF01602.15 EDP42712.1 - 2.1e-88 296.9 10.8 3.8e-88 296.0 7.5 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDP42712.1 - 1.4e-05 25.0 7.7 0.00073 19.4 0.2 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDP42712.1 - 2.8e-05 24.2 4.8 0.15 12.3 0.0 4.6 4 3 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EDP42712.1 - 0.0081 16.1 4.2 6.4 7.1 0.1 5.2 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EDP42712.1 - 0.13 12.0 1.0 16 5.5 0.1 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Tim54 PF11711.3 EDP42715.1 - 1.9e-57 194.6 0.0 5.3e-57 193.1 0.0 1.7 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SH3BP5 PF05276.9 EDP42715.1 - 0.037 13.3 2.6 6 6.0 0.1 2.9 3 0 0 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) PNP_UDP_1 PF01048.15 EDP42716.1 - 1.3e-34 119.1 0.2 1.5e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily mRNA_triPase PF02940.10 EDP42717.1 - 1.4e-35 123.0 0.7 1.6e-35 122.8 0.5 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Pkinase PF00069.20 EDP42718.1 - 7.7e-57 192.3 0.0 1.1e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42718.1 - 2.8e-30 105.2 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42718.1 - 0.0026 16.7 0.6 0.054 12.4 0.4 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP42718.1 - 0.024 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RimM PF01782.13 EDP42718.1 - 0.16 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 RimM N-terminal domain MutS_V PF00488.16 EDP42719.1 - 2.2e-78 262.9 0.1 3.4e-78 262.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDP42719.1 - 7.2e-39 133.6 0.5 1.3e-38 132.8 0.3 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDP42719.1 - 1.3e-35 121.7 0.0 9.9e-35 118.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EDP42719.1 - 8.1e-13 48.6 0.0 1.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EDP42719.1 - 6.9e-08 32.5 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Nop14 PF04147.7 EDP42719.1 - 0.31 8.9 12.0 0.44 8.4 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EDP42719.1 - 0.4 8.6 12.9 0.71 7.8 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein FAT PF02259.18 EDP42720.1 - 9e-114 380.1 0.1 2.5e-113 378.6 0.1 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EDP42720.1 - 5.4e-54 183.1 0.1 9.3e-54 182.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EDP42720.1 - 1.9e-52 177.4 0.0 1.1e-51 174.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EDP42720.1 - 5.2e-41 138.7 0.2 5.2e-41 138.7 0.1 2.8 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EDP42720.1 - 7.1e-18 64.6 22.9 0.0004 20.6 0.0 9.9 8 1 3 11 11 11 5 HEAT repeats FATC PF02260.15 EDP42720.1 - 1.9e-15 55.9 0.2 5.1e-15 54.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EDP42720.1 - 2.3e-10 40.6 25.7 0.003 17.9 0.1 12.5 12 1 3 15 15 13 3 HEAT-like repeat HEAT PF02985.17 EDP42720.1 - 1.5e-08 34.0 21.2 0.013 15.4 0.1 10.7 12 0 0 12 12 10 2 HEAT repeat TPR_19 PF14559.1 EDP42720.1 - 0.012 15.9 0.7 8 6.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Cnd1 PF12717.2 EDP42720.1 - 0.046 13.5 2.1 3.1 7.5 0.0 4.8 4 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EDP42720.1 - 0.42 11.2 8.1 91 3.9 0.4 7.1 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat TPR_16 PF13432.1 EDP42720.1 - 0.69 10.6 9.6 3 8.6 0.4 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat PFU PF09070.6 EDP42721.1 - 1.1e-34 118.8 0.0 1.7e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EDP42721.1 - 4.3e-23 80.2 28.6 6.4e-08 32.1 2.7 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PUL PF08324.6 EDP42721.1 - 2.2e-20 72.5 0.0 3.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EDP42721.1 - 4e-05 23.3 0.0 0.16 11.7 0.0 3.6 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQ-loop PF04193.9 EDP42722.1 - 6.5e-19 67.2 8.9 2.2e-10 39.9 2.8 2.7 2 0 0 2 2 2 2 PQ loop repeat Syndecan PF01034.15 EDP42722.1 - 2.1 8.0 0.0 2.1 8.0 0.0 3.0 4 0 0 4 4 4 0 Syndecan domain YfhO PF09586.5 EDP42722.1 - 5.9 4.7 7.2 0.2 9.6 0.8 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Endonuclease_NS PF01223.18 EDP42723.1 - 3.2e-51 173.9 0.0 4.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Aminotran_3 PF00202.16 EDP42724.1 - 2.9e-108 361.7 0.0 3.8e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDP42724.1 - 0.0028 16.6 0.0 0.0064 15.4 0.0 1.7 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDP42724.1 - 0.0071 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Cyt-b5 PF00173.23 EDP42725.1 - 1.7e-12 46.9 0.0 2.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MHC2-interact PF09307.5 EDP42725.1 - 0.0058 16.4 0.2 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 CLIP, MHC2 interacting Ribosomal_L7Ae PF01248.21 EDP42726.1 - 3.3e-13 48.9 0.0 6.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SR-25 PF10500.4 EDP42726.1 - 0.051 13.0 10.7 0.083 12.3 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4193 PF13834.1 EDP42726.1 - 0.11 12.7 3.2 0.22 11.6 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Ycf1 PF05758.7 EDP42726.1 - 0.23 9.1 1.6 0.18 9.5 1.1 1.1 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 EDP42726.1 - 1.4 8.8 7.3 2 8.3 5.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2457 PF10446.4 EDP42726.1 - 1.4 7.5 12.0 1.9 7.1 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Atrophin-1 PF03154.10 EDP42726.1 - 1.6 6.7 3.7 1.9 6.5 2.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family NARP1 PF12569.3 EDP42726.1 - 3.2 6.3 11.1 3.9 6.1 7.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FYDLN_acid PF09538.5 EDP42726.1 - 4.3 7.9 14.3 24 5.5 9.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.1 EDP42726.1 - 5.2 6.7 6.5 8.8 5.9 4.5 1.4 1 0 0 1 1 1 0 FAM176 family BLVR PF06375.6 EDP42726.1 - 6.2 6.6 18.6 3.3 7.5 11.3 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EDP42726.1 - 8.1 6.2 12.6 4 7.2 7.3 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal tRNA-synt_1b PF00579.20 EDP42727.1 - 3.4e-67 226.6 0.0 4.1e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peroxin-13_N PF04088.8 EDP42728.1 - 1.3e-49 168.1 0.0 2.5e-49 167.2 0.0 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EDP42728.1 - 5.6e-12 44.9 0.0 9.1e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EDP42728.1 - 7e-12 44.7 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDP42728.1 - 1.8e-10 40.0 0.0 3.1e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF4102 PF13356.1 EDP42728.1 - 0.31 10.9 1.7 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) Ribosomal_L16 PF00252.13 EDP42729.1 - 1.9e-30 105.3 0.0 2.5e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RPA_interact_N PF14766.1 EDP42729.1 - 0.063 12.7 0.3 0.15 11.5 0.2 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF3212 PF11486.3 EDP42729.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) Rep_fac-A_C PF08646.5 EDP42731.1 - 1.9e-50 170.3 0.0 2.7e-47 160.1 0.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EDP42731.1 - 8e-13 48.0 0.1 9.9e-10 38.1 0.0 3.4 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EDP42731.1 - 1.3e-10 40.9 0.5 3e-10 39.8 0.3 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain PH PF00169.24 EDP42732.1 - 6.9e-09 35.8 0.0 1.6e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 EDP42732.1 - 3.9e-08 33.4 0.7 9.3e-07 29.0 0.5 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDP42732.1 - 0.057 13.6 0.0 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ist1 PF03398.9 EDP42733.1 - 1.4e-50 170.9 3.3 1.6e-50 170.7 2.3 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DNA_primase_S PF01896.14 EDP42734.1 - 3.1e-52 176.2 0.0 5.1e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Pyridoxal_deC PF00282.14 EDP42735.1 - 2.2e-56 190.9 0.0 2.7e-55 187.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 EDP42735.1 - 0.029 12.9 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EDP42735.1 - 0.054 12.6 0.2 0.1 11.7 0.1 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 EDP42735.1 - 0.058 12.1 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Pkinase PF00069.20 EDP42736.1 - 3.6e-69 232.8 0.1 5.1e-69 232.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42736.1 - 2.7e-43 147.9 0.0 4.4e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EDP42736.1 - 1.1e-29 102.2 0.0 1.1e-14 54.1 0.0 3.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 EDP42736.1 - 7.1e-06 25.1 0.0 3.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 EDP42736.1 - 0.037 13.5 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) BRCA-2_OB1 PF09103.5 EDP42737.1 - 0.033 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Herpes_gI PF01688.12 EDP42737.1 - 0.053 12.6 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I BRCA-2_OB1 PF09103.5 EDP42738.1 - 2.6e-18 65.8 0.0 3.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EDP42738.1 - 3e-05 23.6 1.7 4.9e-05 22.9 1.2 1.3 1 0 0 1 1 1 1 BRCA2, helical SIS PF01380.17 EDP42740.1 - 3.8e-60 201.2 0.1 6.5e-33 113.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EDP42740.1 - 1.2e-27 96.6 0.0 1.6e-19 69.8 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDP42740.1 - 1.5e-19 70.2 0.0 3.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDP42740.1 - 9.2e-13 48.0 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDP42740.1 - 4.1e-07 28.9 0.0 6.9e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Plasmid_Txe PF06769.8 EDP42740.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded toxin Txe SIS_2 PF13580.1 EDP42740.1 - 0.12 12.1 0.0 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 SIS domain Helicase_C_2 PF13307.1 EDP42741.1 - 3.7e-52 176.6 0.0 1.3e-51 174.8 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDP42741.1 - 8.8e-45 152.2 0.1 1.6e-44 151.3 0.0 1.5 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 EDP42741.1 - 0.0018 17.8 0.0 0.012 15.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EDP42741.1 - 0.0081 15.4 0.1 0.054 12.7 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 EDP42741.1 - 0.011 15.6 0.1 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDP42741.1 - 0.035 14.2 2.5 3.8 7.6 0.2 3.1 3 0 0 3 3 3 0 AAA domain NUMOD1 PF07453.8 EDP42742.1 - 0.093 12.6 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain GRAB PF10375.4 EDP42743.1 - 4.5e-08 32.3 0.9 9.2e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 GRIP-related Arf-binding domain Phospholamban PF04272.9 EDP42743.1 - 0.015 14.7 1.0 0.099 12.0 0.0 2.3 2 0 0 2 2 2 0 Phospholamban Ribosomal_S10 PF00338.17 EDP42744.1 - 4.5e-30 103.3 0.5 5.2e-30 103.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L18e PF00828.14 EDP42745.1 - 1e-31 109.9 0.1 1.5e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 IBR PF01485.16 EDP42746.1 - 1.4e-19 69.7 43.2 5.3e-11 42.2 2.9 4.4 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EDP42746.1 - 3.8e-05 23.2 5.6 3.8e-05 23.2 3.9 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP42746.1 - 0.00075 19.4 5.1 0.00075 19.4 3.5 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDP42746.1 - 0.0011 18.5 15.6 0.0078 15.9 1.0 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.1 EDP42746.1 - 0.0019 17.9 5.2 0.0019 17.9 3.6 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDP42746.1 - 0.039 13.8 0.7 0.039 13.8 0.5 4.7 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING DUF1488 PF07369.6 EDP42746.1 - 0.045 13.5 0.9 4.8 7.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1488) 3HCDH_N PF02737.13 EDP42747.1 - 1.8e-54 184.1 1.9 2.8e-54 183.5 1.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EDP42747.1 - 7.7e-31 106.3 0.0 1.7e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.16 EDP42747.1 - 0.004 16.9 0.1 0.0077 16.0 0.1 1.5 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EDP42747.1 - 0.0051 15.8 0.6 0.0095 14.9 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1104 PF06518.6 EDP42747.1 - 0.0057 16.7 0.6 1.1 9.4 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) UDPG_MGDP_dh_N PF03721.9 EDP42747.1 - 0.028 13.7 1.8 0.12 11.6 1.3 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_L11 PF00298.14 EDP42747.1 - 0.033 14.3 2.5 0.051 13.7 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain F420_oxidored PF03807.12 EDP42747.1 - 0.79 10.1 4.9 19 5.7 3.4 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_2 PF00535.21 EDP42748.1 - 4.5e-32 111.0 0.0 5.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDP42748.1 - 4e-13 49.7 0.0 7.4e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EDP42748.1 - 7e-09 35.1 0.0 9.4e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDP42748.1 - 0.00061 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EDP42748.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 WD40 PF00400.27 EDP42749.1 - 6.3e-38 127.3 7.0 7.9e-12 44.5 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EDP42749.1 - 5.4e-24 84.0 7.1 1.2e-23 82.9 5.0 1.5 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EDP42749.1 - 0.00058 19.6 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A NT-C2 PF10358.4 EDP42750.1 - 9.2e-10 38.1 0.0 4.2e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Pribosyltran_N PF13793.1 EDP42751.1 - 6.6e-44 148.3 0.3 1.5e-42 144.0 0.0 2.7 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDP42751.1 - 9.8e-38 129.7 1.2 6e-33 114.1 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDP42751.1 - 1.1e-10 41.3 0.4 4.1e-10 39.4 0.3 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDP42751.1 - 0.0038 16.4 0.1 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase LSM PF01423.17 EDP42752.1 - 1.9e-15 56.1 0.6 2.4e-15 55.8 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDP42752.1 - 0.055 13.4 0.2 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 EDP42752.1 - 0.11 12.2 0.5 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 EDP42752.1 - 0.15 11.7 0.1 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) XPG_I PF00867.13 EDP42753.1 - 8.1e-27 93.1 0.0 1.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EDP42753.1 - 1.1e-05 25.0 0.1 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EDP42753.1 - 0.0078 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TFIIIC_sub6 PF10419.4 EDP42754.1 - 1.7e-10 40.1 0.1 2.6e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 TFIIIC subunit UDPG_MGDP_dh_N PF03721.9 EDP42755.1 - 3e-55 186.4 0.0 5.9e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EDP42755.1 - 1.5e-34 118.3 0.0 3.9e-34 117.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EDP42755.1 - 6.9e-31 106.3 0.0 1.2e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Saccharop_dh PF03435.13 EDP42755.1 - 0.018 14.0 0.0 0.056 12.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EDP42755.1 - 0.087 12.8 0.0 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Abhydrolase_6 PF12697.2 EDP42756.1 - 0.019 14.8 0.3 0.057 13.2 0.2 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L1 PF00687.16 EDP42757.1 - 4.2e-56 189.7 0.0 6e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Herpes_V23 PF01802.12 EDP42757.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF1077 PF06417.7 EDP42758.1 - 8.7e-42 141.4 4.6 1.1e-41 141.1 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Pyr_redox PF00070.22 EDP42759.1 - 6.9e-14 52.0 0.0 1.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDP42759.1 - 8.9e-06 25.7 0.1 0.015 15.1 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP42759.1 - 3.1e-05 24.1 0.0 0.0052 16.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDP42759.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDP42759.1 - 0.057 13.1 0.1 19 5.0 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ribosomal_S24e PF01282.14 EDP42760.1 - 6.1e-33 112.4 0.0 9.2e-33 111.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e LSM PF01423.17 EDP42761.1 - 9.2e-14 50.7 0.0 1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EDP42762.1 - 1.7e-08 34.0 0.0 7.8e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDP42762.1 - 0.02 14.6 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L5 Clathrin PF00637.15 EDP42763.1 - 3.1e-15 56.0 0.1 7.8e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EDP42763.1 - 0.016 14.9 6.7 0.12 12.1 1.4 3.3 3 0 0 3 3 3 0 Ring finger domain WD40 PF00400.27 EDP42763.1 - 0.053 13.4 0.0 0.24 11.3 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EDP42763.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-RING_5 PF14634.1 EDP42763.1 - 1.6 8.5 7.4 0.15 11.8 1.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 EDP42763.1 - 5.4 7.1 6.4 2.1 8.5 0.6 2.9 3 0 0 3 3 3 0 RING-H2 zinc finger GRIM-19 PF06212.7 EDP42764.1 - 1.1e-17 63.9 0.0 1.3e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Nop14 PF04147.7 EDP42765.1 - 2e-218 727.4 21.0 2.3e-218 727.1 14.5 1.0 1 0 0 1 1 1 1 Nop14-like family Cullin_binding PF03556.10 EDP42766.1 - 0.0024 18.0 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Cullin binding DCAF15_WD40 PF14939.1 EDP42766.1 - 0.079 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat PAR1 PF06521.6 EDP42766.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 PAR1 protein LSM PF01423.17 EDP42767.1 - 6.1e-16 57.7 0.2 2.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 2 LSM domain SM-ATX PF14438.1 EDP42767.1 - 0.0022 17.8 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.1 EDP42768.1 - 1.4e-11 43.4 3.9 1.4e-11 43.4 2.7 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EDP42768.1 - 5.9e-05 21.9 1.4 5.9e-05 21.9 1.0 2.0 1 1 1 2 2 2 1 PUCC protein 14-3-3 PF00244.15 EDP42769.1 - 2.1e-117 390.3 6.4 2.4e-117 390.1 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Adaptin_N PF01602.15 EDP42770.1 - 7e-93 311.7 5.7 9.1e-93 311.3 4.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDP42770.1 - 0.011 16.0 2.4 0.074 13.3 0.1 2.8 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EDP42770.1 - 0.034 14.2 0.1 4.2 7.7 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat RRN3 PF05327.6 EDP42771.1 - 3e-99 332.6 0.0 4.9e-98 328.6 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.17 EDP42772.1 - 7.7e-50 168.4 0.0 9.3e-50 168.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP42772.1 - 1.3e-15 57.9 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP42772.1 - 5.4e-10 38.7 0.0 7.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDP42772.1 - 9.3e-05 21.6 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EDP42772.1 - 0.0054 15.4 1.1 1 7.9 0.1 2.5 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 EDP42772.1 - 0.015 15.4 0.1 0.15 12.2 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EDP42772.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EDP42772.1 - 0.072 13.2 0.1 0.19 11.8 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EDP42772.1 - 0.089 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 EDP42772.1 - 0.1 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain SHS2_Rpb7-N PF03876.12 EDP42773.1 - 4.3e-08 33.1 0.0 7.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Thioredoxin PF00085.15 EDP42774.1 - 1.3e-15 56.9 0.0 2e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDP42774.1 - 2e-06 27.8 0.0 2.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EDP42774.1 - 0.00019 21.4 0.0 0.00027 20.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDP42774.1 - 0.00073 19.7 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EDP42774.1 - 0.002 17.6 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF836 PF05768.9 EDP42774.1 - 0.0048 17.1 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.16 EDP42774.1 - 0.01 15.5 0.0 0.053 13.1 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.1 EDP42774.1 - 0.018 14.5 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RasGAP PF00616.14 EDP42775.1 - 7.7e-08 32.2 0.0 3.7e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Methyltransf_16 PF10294.4 EDP42776.1 - 1.8e-14 53.5 0.0 1.9e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 EDP42776.1 - 0.0008 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EDP42776.1 - 0.0049 17.4 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42776.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MT-A70 PF05063.9 EDP42777.1 - 2.3e-53 180.3 0.0 4.1e-53 179.5 0.0 1.4 1 1 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EDP42777.1 - 0.0055 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 EDP42779.1 - 4.1e-44 146.9 25.5 3.8e-10 39.2 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EDP42779.1 - 1.1e-12 47.4 2.2 1.1e-12 47.4 1.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDP42779.1 - 6.8e-08 31.9 0.6 1.6e-07 30.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EDP42779.1 - 4.7e-07 29.5 0.0 0.0089 15.7 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EDP42779.1 - 0.049 13.9 0.4 9.8 6.6 0.0 3.4 2 2 1 3 3 3 0 PQQ-like domain Nup160 PF11715.3 EDP42779.1 - 1.7 6.6 6.4 7.9 4.4 0.0 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Pal1 PF08316.6 EDP42780.1 - 5.3e-14 52.8 5.3 6.9e-14 52.4 0.6 2.5 1 1 1 2 2 2 1 Pal1 cell morphology protein SCP2 PF02036.12 EDP42781.1 - 1.3e-23 83.2 1.5 1.6e-23 82.9 1.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EDP42781.1 - 0.007 16.3 0.6 0.0084 16.0 0.4 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Bot1p PF12298.3 EDP42783.1 - 1.5e-22 80.3 0.1 2.2e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 EDP42783.1 - 0.0072 16.3 0.1 0.0072 16.3 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 His_Phos_2 PF00328.17 EDP42785.1 - 4.9e-70 236.5 0.1 6.8e-70 236.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EDP42785.1 - 3.4e-08 33.1 0.0 6.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain LETM1 PF07766.8 EDP42786.1 - 4.1e-13 48.9 0.9 5.4e-13 48.5 0.6 1.2 1 0 0 1 1 1 1 LETM1-like protein LSM PF01423.17 EDP42787.1 - 8.8e-16 57.2 0.3 1.3e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDP42787.1 - 0.089 12.7 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain WD40 PF00400.27 EDP42789.1 - 1.8e-06 27.5 5.0 0.0034 17.2 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat TRAPPC-Trs85 PF12739.2 EDP42790.1 - 3.9e-58 197.0 13.9 3.9e-58 197.0 9.7 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Gryzun PF07919.7 EDP42790.1 - 0.00088 17.7 0.0 0.002 16.5 0.0 1.4 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Pex24p PF06398.6 EDP42791.1 - 2.5e-29 102.2 0.2 3.5e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FAD_binding_6 PF00970.19 EDP42792.1 - 4.1e-11 42.8 0.0 7.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EDP42792.1 - 5.6e-10 39.5 0.1 1e-08 35.5 0.1 2.3 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 EDP42792.1 - 2.2e-09 37.8 0.0 4.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 EDP42792.1 - 2.7e-06 27.1 0.1 4.7e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EDP42792.1 - 0.0025 17.7 0.6 0.0071 16.2 0.1 1.9 2 1 1 3 3 3 1 Ferric reductase NAD binding domain RRM_1 PF00076.17 EDP42793.1 - 1.5e-40 136.6 0.0 4.3e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42793.1 - 5.5e-33 112.7 0.0 2.5e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42793.1 - 6.6e-21 73.9 0.0 1e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP42793.1 - 0.03 14.0 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb1_5 PF04998.12 EDP42794.1 - 2.5e-95 318.8 0.2 3.6e-95 318.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDP42794.1 - 2e-86 290.3 0.0 2.7e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EDP42794.1 - 1.1e-65 220.6 0.0 2.4e-65 219.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDP42794.1 - 1.2e-38 132.3 0.0 3.3e-38 130.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDP42794.1 - 6.6e-31 106.2 0.0 1.5e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-ISL3 PF14690.1 EDP42794.1 - 0.093 12.7 3.6 0.45 10.5 0.2 2.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 EDP42794.1 - 0.094 12.5 0.8 3 7.7 0.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon ThiF PF00899.16 EDP42796.1 - 2.7e-47 160.0 0.0 3.1e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EDP42796.1 - 2.4e-39 134.3 0.0 4.4e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EDP42796.1 - 1.7e-35 120.3 0.9 1.6e-25 88.4 0.0 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDP42796.1 - 5.9e-27 92.7 0.6 5.8e-23 80.0 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site End_beta_barrel PF12195.3 EDP42796.1 - 0.066 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Pyr_redox PF00070.22 EDP42796.1 - 0.13 12.6 0.2 21 5.5 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med13_C PF06333.7 EDP42799.1 - 1.5e-10 40.2 0.0 1.5e-10 40.2 0.0 2.2 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal DUF1192 PF06698.6 EDP42800.1 - 0.016 14.9 0.4 0.024 14.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) AF0941-like PF14591.1 EDP42800.1 - 0.28 11.2 1.9 2.2 8.3 1.4 1.9 1 1 1 2 2 2 0 AF0941-like DUF3694 PF12473.3 EDP42801.1 - 0.0085 15.7 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein CDT1 PF08839.6 EDP42802.1 - 1.3e-06 28.4 0.0 0.0041 17.0 0.0 2.6 2 1 0 2 2 2 2 DNA replication factor CDT1 like Iso_dh PF00180.15 EDP42803.1 - 4e-88 295.6 0.0 4.9e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Spo0A_C PF08769.6 EDP42803.1 - 0.08 12.8 0.2 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal GTP_EFTU PF00009.22 EDP42804.1 - 6.3e-45 152.9 0.0 9e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDP42804.1 - 7.8e-07 29.0 0.0 6.4e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDP42804.1 - 0.00021 21.7 0.1 0.0091 16.4 0.1 2.4 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EDP42804.1 - 0.0011 19.0 0.2 0.078 13.0 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EDP42804.1 - 0.0012 18.9 0.0 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Arf PF00025.16 EDP42804.1 - 0.0027 16.9 0.0 0.91 8.7 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EDP42804.1 - 0.051 12.2 0.8 0.074 11.7 0.1 1.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 EDP42804.1 - 0.055 13.3 0.0 0.31 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EDP42804.1 - 0.091 12.1 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.13 EDP42804.1 - 0.11 11.7 0.0 4.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.5 EDP42804.1 - 0.17 11.0 0.0 3.2 6.9 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Myb_DNA-binding PF00249.26 EDP42805.1 - 2.4e-28 97.8 5.8 6e-12 45.4 0.2 4.3 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP42805.1 - 1.5e-22 79.4 1.4 2.5e-08 33.9 0.0 4.8 3 1 1 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDP42805.1 - 0.043 13.9 6.2 0.51 10.4 0.0 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EDP42805.1 - 0.051 13.4 0.4 3.2 7.7 0.0 3.0 2 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sedlin_N PF04628.8 EDP42806.1 - 3.3e-22 78.7 0.2 9.7e-19 67.5 0.1 2.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EDP42806.1 - 5.9e-08 32.5 0.0 8.9e-08 31.9 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family BRICHOS PF04089.9 EDP42806.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 BRICHOS domain Inhibitor_I9 PF05922.11 EDP42807.1 - 0.0033 17.9 0.0 0.004 17.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_30 PF05430.6 EDP42807.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PRKCSH_1 PF13015.1 EDP42808.1 - 1.1e-28 99.5 0.3 1.7e-28 99.0 0.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EDP42808.1 - 6.7e-11 42.8 0.6 1.7e-10 41.5 0.4 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HR1 PF02185.11 EDP42808.1 - 0.0043 16.7 1.2 0.22 11.3 0.2 2.3 2 0 0 2 2 2 1 Hr1 repeat Phasin PF05597.6 EDP42808.1 - 0.098 12.4 1.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Acyltransferase PF01553.16 EDP42809.1 - 4.9e-35 119.8 0.0 6.9e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase BTB PF00651.26 EDP42810.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain RabGAP-TBC PF00566.13 EDP42811.1 - 8e-20 71.2 5.8 4.5e-16 58.9 0.8 3.0 3 0 0 3 3 3 3 Rab-GTPase-TBC domain Rab5ip PF07019.7 EDP42812.1 - 1.9e-05 24.7 11.7 0.0008 19.4 8.1 2.1 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF1774 PF08611.5 EDP42812.1 - 0.029 14.5 0.3 0.05 13.7 0.2 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) DUF2456 PF10445.4 EDP42812.1 - 4.9 7.1 6.6 2 8.3 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2456) WD40 PF00400.27 EDP42813.1 - 7.4e-15 54.1 8.0 4e-09 36.0 1.2 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EDP42813.1 - 0.0019 17.0 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region AAA_2 PF07724.9 EDP42814.1 - 1.7e-51 174.5 0.0 2.9e-49 167.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDP42814.1 - 1.9e-26 92.8 0.0 8.6e-15 55.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDP42814.1 - 2.3e-21 75.4 0.1 1e-20 73.4 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EDP42814.1 - 8e-15 54.7 0.0 3.5e-09 36.5 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 EDP42814.1 - 2e-12 46.8 5.3 1.9e-06 27.6 0.2 3.9 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 EDP42814.1 - 2.4e-12 47.2 5.2 3.9e-06 26.9 0.0 5.8 4 2 0 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 EDP42814.1 - 9.9e-10 38.6 2.0 0.015 15.4 0.0 5.5 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EDP42814.1 - 1.2e-07 31.3 0.0 1.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EDP42814.1 - 6.2e-06 27.0 3.1 0.75 10.6 2.4 3.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDP42814.1 - 8.4e-06 25.3 0.0 0.068 12.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDP42814.1 - 1e-05 24.7 0.2 0.016 14.3 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EDP42814.1 - 5.5e-05 23.2 0.0 0.28 11.3 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.1 EDP42814.1 - 6.9e-05 22.7 2.3 0.13 12.0 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EDP42814.1 - 0.0001 21.9 0.1 0.089 12.5 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 EDP42814.1 - 0.00016 21.4 1.6 0.0051 16.5 0.0 3.8 3 2 0 4 4 4 1 Archaeal ATPase T2SE PF00437.15 EDP42814.1 - 0.00024 20.0 0.0 0.0032 16.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.1 EDP42814.1 - 0.00025 21.0 0.0 0.23 11.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDP42814.1 - 0.00045 19.4 0.0 0.26 10.4 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDP42814.1 - 0.00049 19.7 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDP42814.1 - 0.0012 18.0 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDP42814.1 - 0.0023 17.3 1.0 0.47 9.8 0.0 3.6 3 1 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.4 EDP42814.1 - 0.0079 14.8 0.0 2.4 6.6 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EDP42814.1 - 0.009 16.3 4.5 0.98 9.7 0.0 3.5 3 1 0 3 3 2 1 AAA domain PhoH PF02562.11 EDP42814.1 - 0.026 13.7 0.1 1 8.5 0.0 3.0 4 0 0 4 4 3 0 PhoH-like protein MobB PF03205.9 EDP42814.1 - 0.026 14.2 0.0 9.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EDP42814.1 - 0.041 13.3 0.0 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 EDP42814.1 - 0.052 12.9 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 EDP42814.1 - 0.07 12.7 0.0 13 5.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) EMP24_GP25L PF01105.19 EDP42814.1 - 0.07 12.8 0.8 0.16 11.6 0.6 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_10 PF12846.2 EDP42814.1 - 0.12 11.8 8.3 5.8 6.2 0.0 4.1 3 2 0 4 4 4 0 AAA-like domain Laminin_II PF06009.7 EDP42814.1 - 0.37 10.5 7.5 0.1 12.3 2.2 2.3 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 EDP42814.1 - 3.8 7.0 14.1 15 5.1 9.8 2.0 1 1 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EDP42814.1 - 4.7 7.4 12.5 3.5 7.8 0.0 3.4 3 1 0 3 3 2 0 AAA domain AAA_13 PF13166.1 EDP42814.1 - 8.2 4.7 9.9 22 3.3 6.4 1.5 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 EDP42815.1 - 1.4e-12 47.3 5.0 2.3e-12 46.7 3.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDP42815.1 - 7.9e-10 38.4 3.9 1.3e-09 37.7 2.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.13 EDP42815.1 - 0.0043 16.7 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper Striatin PF08232.7 EDP42815.1 - 0.024 14.9 0.4 0.079 13.2 0.0 2.0 1 1 1 2 2 2 0 Striatin family HAP1_N PF04849.8 EDP42815.1 - 0.027 13.4 1.2 0.041 12.8 0.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.12 EDP42815.1 - 0.035 14.3 1.6 0.078 13.2 1.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor RRM_1 PF00076.17 EDP42816.1 - 1.9e-20 72.2 0.1 5.6e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42816.1 - 1.1e-15 57.3 0.1 1.6e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42816.1 - 9e-11 41.4 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.17 EDP42817.1 - 4.6e-79 265.9 0.0 5.5e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 EDP42817.1 - 0.1 13.2 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Fic/DOC family Pkinase PF00069.20 EDP42818.1 - 2e-72 243.4 0.0 2.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42818.1 - 6e-41 140.2 0.0 8.1e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42818.1 - 6.2e-10 38.5 0.0 9.9e-10 37.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP42818.1 - 0.001 18.1 0.5 0.0038 16.3 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP42818.1 - 0.02 14.6 0.4 0.12 12.0 0.3 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family HAD PF12710.2 EDP42819.1 - 1.4e-08 35.1 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EDP42819.1 - 8.4e-06 25.2 0.1 8.9e-05 21.9 0.0 2.0 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EDP42819.1 - 0.0038 17.4 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EDP42820.1 - 4.6e-58 195.6 0.0 7.5e-58 194.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EDP42820.1 - 2.8e-10 39.3 0.2 7.6e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NUC153 PF08159.7 EDP42821.1 - 6.2e-14 51.2 0.3 1.1e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EDP42821.1 - 0.0048 16.7 0.3 7.6 6.5 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Lgl_C PF08596.5 EDP42821.1 - 0.18 10.2 0.0 0.29 9.5 0.0 1.4 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Trypan_PARP PF05887.6 EDP42821.1 - 0.34 10.7 11.4 0.95 9.2 7.9 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L11 PF00298.14 EDP42822.1 - 6.6e-24 83.8 1.6 1.1e-23 83.1 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EDP42822.1 - 4.2e-22 77.3 1.1 1.8e-21 75.3 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain adh_short PF00106.20 EDP42823.1 - 1.3e-30 106.5 0.4 1.9e-30 105.9 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDP42823.1 - 2.3e-27 96.2 0.1 3.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDP42823.1 - 5.3e-17 62.0 0.1 6.9e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDP42823.1 - 3.6e-07 29.8 0.3 4.4e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 EDP42823.1 - 9.6e-05 21.7 2.7 0.00022 20.6 1.9 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.12 EDP42823.1 - 0.00059 20.2 0.6 0.15 12.4 0.2 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EDP42823.1 - 0.0011 18.6 0.3 0.062 12.9 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EDP42823.1 - 0.078 11.9 0.7 2.8 6.8 0.0 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NifU_N PF01592.11 EDP42824.1 - 5.5e-52 175.0 0.1 6.8e-52 174.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Snf7 PF03357.16 EDP42825.1 - 3.4e-29 101.4 7.6 4e-29 101.1 5.2 1.0 1 0 0 1 1 1 1 Snf7 Bac_GDH PF05088.7 EDP42825.1 - 0.035 11.5 4.3 0.038 11.4 3.0 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase zf-C4H2 PF10146.4 EDP42825.1 - 0.084 12.8 4.0 0.091 12.7 2.2 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein PRANC PF09372.5 EDP42825.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 PRANC domain DUF2203 PF09969.4 EDP42825.1 - 2.6 8.2 7.2 0.29 11.3 1.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF947 PF06102.7 EDP42826.1 - 4.8e-39 133.8 15.9 4.8e-39 133.8 11.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Utp14 PF04615.8 EDP42827.1 - 6.8e-115 384.9 41.9 3.1e-68 230.6 0.1 2.0 2 0 0 2 2 2 2 Utp14 protein Utp14 PF04615.8 EDP42828.1 - 4.4e-17 61.5 6.5 4.4e-17 61.5 4.5 2.1 1 1 1 2 2 2 1 Utp14 protein TFIIF_alpha PF05793.7 EDP42828.1 - 1.4 7.1 27.5 1.7 6.9 19.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 EDP42828.1 - 6.5 6.0 16.2 5.9 6.1 10.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) UPF0113 PF03657.8 EDP42829.1 - 3.5e-11 43.0 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Methyltransf_8 PF05148.10 EDP42831.1 - 1.7e-48 165.1 0.0 1.1e-22 80.8 0.0 3.0 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 EDP42831.1 - 4.3e-05 23.2 0.0 0.00013 21.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP42831.1 - 0.00026 21.4 0.1 0.0024 18.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP42831.1 - 0.0057 17.2 0.2 0.067 13.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP42831.1 - 0.027 14.0 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EDP42831.1 - 0.059 12.7 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EDP42831.1 - 0.13 11.3 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Sec7 PF01369.15 EDP42832.1 - 1.7e-62 210.4 0.1 5.6e-62 208.7 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EDP42832.1 - 1.6e-51 174.1 2.3 6.3e-51 172.1 1.6 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDP42832.1 - 9.6e-28 95.5 3.4 2.6e-26 90.9 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) eIF-6 PF01912.13 EDP42833.1 - 3.3e-82 274.4 0.5 4.1e-82 274.1 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family zf-Tim10_DDP PF02953.10 EDP42834.1 - 5.4e-19 67.2 1.4 6.2e-19 67.0 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tho2 PF11262.3 EDP42835.1 - 2.4e-65 220.5 0.0 3.8e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EDP42835.1 - 3.6e-28 97.1 0.0 8.3e-28 95.9 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Asp-B-Hydro_N PF05279.6 EDP42835.1 - 4.3 7.1 18.2 14 5.4 12.6 1.8 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 EDP42835.1 - 4.7 4.7 5.0 6.8 4.2 3.5 1.1 1 0 0 1 1 1 0 Ycf1 Adap_comp_sub PF00928.16 EDP42836.1 - 1.5e-40 138.9 0.0 1.9e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Tom22 PF04281.8 EDP42836.1 - 0.23 11.0 4.1 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 WLM PF08325.5 EDP42837.1 - 1.1e-20 74.2 0.1 2.2e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 WLM domain Ubiquitin_2 PF14560.1 EDP42837.1 - 0.00017 21.7 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EDP42837.1 - 0.0064 15.8 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_cc PF11790.3 EDP42838.1 - 2.9e-53 180.7 10.2 3.8e-53 180.3 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_2_C PF02836.12 EDP42838.1 - 0.015 14.1 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain SH3_1 PF00018.23 EDP42839.1 - 4.2e-21 74.0 0.0 4.6e-09 35.5 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EDP42839.1 - 4.6e-14 51.7 0.0 7.4e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EDP42839.1 - 3.9e-13 48.6 0.0 7.2e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EDP42839.1 - 0.0032 17.1 0.0 0.011 15.4 0.0 2.0 1 0 0 1 1 1 1 PB1 domain PX PF00787.19 EDP42839.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Phage_term_smal PF05944.7 EDP42840.1 - 9.9e-05 22.0 0.5 2.9 7.5 0.0 3.7 1 1 3 4 4 4 3 Phage small terminase subunit MOZART1 PF12554.3 EDP42840.1 - 0.028 13.8 0.1 38 3.8 0.0 3.3 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated GRIP PF01465.15 EDP42840.1 - 0.52 9.8 9.4 2.4 7.7 0.2 4.2 2 1 3 5 5 5 0 GRIP domain CRF PF00473.12 EDP42840.1 - 2.1 8.4 5.6 1.2e+02 2.9 0.0 3.9 4 0 0 4 4 4 0 Corticotropin-releasing factor family PTR2 PF00854.16 EDP42842.1 - 8.8e-33 113.5 5.9 2.8e-32 111.9 4.1 1.7 1 1 0 1 1 1 1 POT family S4 PF01479.20 EDP42844.1 - 1.3e-09 37.3 0.0 2.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain S-AdoMet_synt_C PF02773.11 EDP42845.1 - 5e-75 249.7 1.4 6.5e-75 249.4 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EDP42845.1 - 3.4e-47 159.3 0.0 6.3e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EDP42845.1 - 1.9e-45 153.1 0.1 4.1e-45 152.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 EDP42845.1 - 0.016 14.2 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Amidinotransferase Imm2 PF14426.1 EDP42845.1 - 0.17 11.9 0.2 34 4.5 0.0 3.0 3 0 0 3 3 3 0 Immunity protein Imm2 DUF3818 PF12825.2 EDP42846.1 - 2.1e-81 273.2 0.0 2.8e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDP42846.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 PX-associated IL3 PF02059.10 EDP42846.1 - 0.25 11.3 0.5 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Interleukin-3 FAD_binding_1 PF00667.15 EDP42847.1 - 3.4e-49 167.2 0.0 5.5e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EDP42847.1 - 3.1e-08 34.1 0.0 9e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EDP42847.1 - 1.2e-07 31.7 0.0 5.5e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Ribosomal_S7e PF01251.13 EDP42848.1 - 4e-75 251.4 0.2 4.5e-75 251.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF1768 PF08719.6 EDP42849.1 - 5.4e-32 110.6 0.0 6.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 EDP42849.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage protein GP30.3 DAD PF02109.11 EDP42850.1 - 3e-40 136.7 1.1 3.4e-40 136.6 0.7 1.0 1 0 0 1 1 1 1 DAD family DUF1600 PF07667.6 EDP42850.1 - 0.15 12.1 1.7 0.26 11.3 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) GTP_EFTU PF00009.22 EDP42851.1 - 7.9e-45 152.5 0.0 1.6e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDP42851.1 - 1.8e-23 82.5 2.0 3.1e-23 81.7 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDP42851.1 - 2.2e-08 34.0 1.0 5.6e-08 32.7 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP42851.1 - 0.00033 20.5 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDP42851.1 - 0.0047 16.5 0.4 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DNA_pol3_beta_2 PF02767.11 EDP42851.1 - 0.19 11.7 1.2 0.69 9.9 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain Ndc1_Nup PF09531.5 EDP42851.1 - 0.57 8.5 2.3 0.86 7.9 1.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAM2 PF07145.10 EDP42851.1 - 2.9 7.5 6.4 18 5.1 0.3 3.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF1640 PF07798.6 EDP42852.1 - 2.6e-14 53.6 4.3 6.5e-14 52.3 3.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Corona_S2 PF01601.11 EDP42852.1 - 0.0093 14.1 0.2 0.013 13.5 0.1 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein OmpH PF03938.9 EDP42852.1 - 0.0094 15.8 1.1 0.021 14.7 0.7 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) COMP PF11598.3 EDP42852.1 - 0.12 12.5 0.2 2.3 8.3 0.0 2.6 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Prominin PF05478.6 EDP42852.1 - 0.13 9.7 1.2 0.18 9.3 0.8 1.1 1 0 0 1 1 1 0 Prominin IncA PF04156.9 EDP42852.1 - 7.3 6.1 13.7 4.7 6.7 7.9 1.8 1 1 0 1 1 1 0 IncA protein Rho_GDI PF02115.12 EDP42853.1 - 1.3e-48 165.1 0.0 1.6e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Complex1_LYR PF05347.10 EDP42854.1 - 1.3e-09 37.6 5.4 2.1e-09 37.0 3.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDP42854.1 - 5.7e-07 29.6 5.1 9e-07 29.0 3.5 1.3 1 0 0 1 1 1 1 Complex1_LYR-like VWA_2 PF13519.1 EDP42855.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Flavin_Reduct PF01613.13 EDP42856.1 - 3e-26 92.1 0.5 3.8e-26 91.7 0.3 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Sedlin_N PF04628.8 EDP42857.1 - 3e-28 98.3 0.0 3.6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EDP42859.1 - 1.8e-61 207.6 0.0 5.8e-61 205.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42859.1 - 1.1e-41 142.6 0.0 1.2e-40 139.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EDP42859.1 - 3.5e-38 131.1 0.1 5.5e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 EDP42859.1 - 0.0017 17.3 0.0 0.015 14.2 0.0 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EDP42859.1 - 0.0071 16.1 1.3 0.072 12.8 0.0 2.9 2 2 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDP42860.1 - 1.3e-66 224.4 0.0 2.5e-66 223.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42860.1 - 2.5e-30 105.4 0.0 4.6e-29 101.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP42860.1 - 7.6e-08 31.6 0.4 0.00014 20.9 0.1 3.0 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EDP42860.1 - 0.004 16.9 0.1 0.61 9.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDP42860.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.1 EDP42860.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SART-1 PF03343.8 EDP42861.1 - 7.4e-91 305.3 27.6 9.2e-91 305.0 19.1 1.1 1 0 0 1 1 1 1 SART-1 family RhoGAP PF00620.22 EDP42862.1 - 2e-23 82.6 0.0 4.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Not3 PF04065.10 EDP42864.1 - 7.8e-49 166.0 9.3 1.2e-48 165.4 6.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EDP42864.1 - 3.6e-44 149.8 9.5 3.6e-44 149.8 6.6 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EDP42864.1 - 0.0025 17.3 2.0 0.0054 16.2 1.4 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF4407 PF14362.1 EDP42864.1 - 1.9 7.3 5.4 1.3 7.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L19 PF01245.15 EDP42865.1 - 3.4e-24 84.8 0.2 5.3e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Aminotran_1_2 PF00155.16 EDP42866.1 - 6.1e-73 245.8 0.0 7.4e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDP42866.1 - 5.7e-08 31.8 0.0 1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDP42866.1 - 0.00017 19.9 0.0 0.00041 18.7 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EDP42866.1 - 0.0061 15.7 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDP42866.1 - 0.017 14.1 0.1 0.038 13.0 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tox-HDC PF15656.1 EDP42866.1 - 0.12 12.6 0.5 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature Ytp1 PF10355.4 EDP42867.1 - 2.3e-97 325.4 3.4 3.6e-97 324.8 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDP42867.1 - 1.1e-09 37.7 1.4 1.1e-09 37.7 0.9 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 EDP42868.1 - 1.1e-22 80.6 0.1 6.2e-22 78.2 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDP42868.1 - 4.7e-21 74.8 0.0 5.2e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EDP42868.1 - 4.4e-06 26.7 1.3 8.1e-06 25.8 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42868.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDP42868.1 - 0.039 12.6 0.6 4.2 5.9 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family C2 PF00168.25 EDP42870.1 - 6.5e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain RasGAP_C PF03836.10 EDP42871.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RasGAP C-terminus TypeIII_RM_meth PF12564.3 EDP42871.1 - 0.15 12.0 1.6 0.77 9.7 0.3 2.1 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Drf_FH3 PF06367.11 EDP42872.1 - 3.5e-47 160.3 0.5 3.5e-47 160.3 0.4 2.2 1 1 1 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EDP42872.1 - 1.6e-42 145.0 0.0 3.3e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Golgin_A5 PF09787.4 EDP42872.1 - 0.0062 15.1 1.2 0.012 14.2 0.9 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 Phage_GP20 PF06810.6 EDP42872.1 - 0.12 11.8 0.5 0.25 10.7 0.3 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 Bacillus_HBL PF05791.6 EDP42872.1 - 0.13 11.5 1.6 5.6 6.2 0.1 2.8 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF745 PF05335.8 EDP42872.1 - 0.27 10.7 2.5 0.19 11.2 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 EDP42872.1 - 1.1 8.8 5.8 1.1 8.7 2.9 1.8 2 0 0 2 2 2 0 IncA protein L51_S25_CI-B8 PF05047.11 EDP42873.1 - 7.1e-05 22.4 0.1 0.00017 21.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain eRF1_2 PF03464.10 EDP42874.1 - 9.8e-44 148.9 0.0 1.7e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDP42874.1 - 2.2e-39 134.2 0.2 4.8e-39 133.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDP42874.1 - 2.3e-27 95.1 0.0 3.6e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Sec16_C PF12931.2 EDP42876.1 - 8.6e-73 245.5 0.0 1.1e-72 245.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EDP42876.1 - 2.6e-30 104.7 0.0 5.2e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Arf PF00025.16 EDP42877.1 - 2e-70 235.5 0.0 2.2e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDP42877.1 - 8.1e-13 48.0 0.0 9.2e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDP42877.1 - 5.7e-11 41.9 0.0 7.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EDP42877.1 - 6.7e-11 41.5 0.2 4.1e-07 29.0 0.1 2.4 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDP42877.1 - 1e-09 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDP42877.1 - 6.5e-06 26.6 0.0 8.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP42877.1 - 0.00046 20.1 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDP42877.1 - 0.055 12.8 0.0 0.36 10.2 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EDP42877.1 - 0.062 12.7 0.1 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GATA PF00320.22 EDP42878.1 - 8.8e-17 60.1 1.0 8.8e-17 60.1 0.7 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 EDP42878.1 - 1.7e-12 46.7 2.2 3.3e-12 45.7 1.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ArfGap PF01412.13 EDP42878.1 - 0.016 15.0 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ABC_tran PF00005.22 EDP42879.1 - 7.2e-36 123.4 0.0 3.7e-35 121.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDP42879.1 - 2.5e-32 112.4 6.5 3.2e-32 112.0 4.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDP42879.1 - 7.4e-07 29.4 0.1 0.0034 17.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EDP42879.1 - 2.2e-06 27.0 0.1 0.0044 16.2 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDP42879.1 - 3.8e-05 23.7 0.1 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EDP42879.1 - 0.0001 22.5 0.0 0.00098 19.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EDP42879.1 - 0.0011 18.4 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EDP42879.1 - 0.0022 17.7 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDP42879.1 - 0.0049 16.7 0.1 0.048 13.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EDP42879.1 - 0.0052 16.9 0.1 0.036 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EDP42879.1 - 0.011 15.5 1.0 0.054 13.4 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EDP42879.1 - 0.024 14.0 0.0 0.075 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EDP42879.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EDP42879.1 - 0.031 13.4 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_1 PF00515.23 EDP42879.1 - 0.042 13.4 2.0 0.11 12.2 1.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_23 PF13476.1 EDP42879.1 - 0.15 12.3 0.4 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDP42879.1 - 0.17 12.7 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.16 EDP42880.1 - 2.7e-28 98.2 0.5 2.7e-28 98.2 0.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily FtsX PF02687.16 EDP42880.1 - 0.075 12.7 0.4 0.49 10.1 0.0 2.5 4 0 0 4 4 4 0 FtsX-like permease family DUF2628 PF10947.3 EDP42880.1 - 0.5 10.1 4.8 0.66 9.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2628) DUF998 PF06197.8 EDP42880.1 - 0.54 9.5 5.1 0.34 10.1 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF998) PepSY_TM PF03929.11 EDP42880.1 - 6.9 7.2 0.0 6.9 7.2 0.0 3.9 5 0 0 5 5 5 0 PepSY-associated TM helix PAP2_C PF14360.1 EDP42880.1 - 9.8 6.5 8.9 1 9.6 0.5 2.9 3 0 0 3 3 3 0 PAP2 superfamily C-terminal WD40 PF00400.27 EDP42881.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat Topoisom_bac PF01131.15 EDP42882.1 - 9.5e-91 304.6 0.0 1.3e-90 304.1 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EDP42882.1 - 8.3e-10 38.5 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 EDP42882.1 - 1.8e-07 30.9 20.9 0.00022 21.0 2.4 2.8 2 0 0 2 2 2 2 GRF zinc finger DUF730 PF05325.6 EDP42882.1 - 0.15 11.8 5.8 0.25 11.1 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF730) HLH PF00010.21 EDP42884.1 - 5e-09 35.7 0.0 1.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HAMP PF00672.20 EDP42885.1 - 3.9e-46 155.0 22.3 6.5e-08 32.6 0.2 8.3 7 1 0 7 7 7 7 HAMP domain Response_reg PF00072.19 EDP42885.1 - 1e-27 96.3 0.6 9.5e-26 90.0 0.6 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EDP42885.1 - 3.2e-26 91.2 0.0 1.1e-25 89.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDP42885.1 - 9.2e-18 64.0 0.4 1.1e-16 60.5 0.3 3.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 EDP42885.1 - 0.00015 21.2 0.1 0.42 10.5 0.0 3.8 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.3 EDP42885.1 - 0.0064 16.2 0.9 4.4 7.0 0.0 4.0 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding BRCA-2_OB3 PF09104.5 EDP42885.1 - 0.16 11.8 1.2 2.9 7.6 0.0 3.2 3 0 0 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Ribosomal_S30AE PF02482.14 EDP42885.1 - 0.16 12.4 3.4 3.2e+02 1.8 0.0 5.7 6 1 1 7 7 7 0 Sigma 54 modulation protein / S30EA ribosomal protein Syntaxin PF00804.20 EDP42885.1 - 0.17 12.0 4.7 29 4.8 0.0 4.4 3 2 2 5 5 5 0 Syntaxin VBS PF08913.5 EDP42885.1 - 0.96 9.7 9.7 9.5 6.4 0.1 4.8 4 2 1 5 5 5 0 Vinculin Binding Site TFIIS_M PF07500.9 EDP42886.1 - 2.6e-20 72.6 0.0 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EDP42886.1 - 2.2e-10 41.0 0.0 4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EDP42886.1 - 2.4e-10 39.9 11.5 4e-10 39.2 7.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EDP42886.1 - 0.03 14.5 2.0 0.12 12.6 1.4 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Porin_3 PF01459.17 EDP42887.1 - 1.4e-66 224.6 0.1 1.6e-66 224.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2460 PF09343.5 EDP42887.1 - 0.014 14.8 0.1 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) MBOAT_2 PF13813.1 EDP42888.1 - 4.3e-06 26.7 5.1 4.3e-06 26.7 3.5 3.2 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family WD40 PF00400.27 EDP42889.1 - 1.2e-06 28.1 7.3 0.0015 18.3 0.0 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Histone PF00125.19 EDP42890.1 - 2.3e-22 78.8 0.1 3.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDP42890.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 EDP42891.1 - 1.4e-13 50.5 0.0 1.6e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42891.1 - 1.4e-05 24.3 0.0 1.7e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EDP42892.1 - 2.5e-15 56.3 0.0 3.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42892.1 - 7e-13 48.2 0.0 9.2e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Glycos_transf_2 PF00535.21 EDP42893.1 - 1.6e-18 66.9 0.0 4.8e-18 65.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDP42893.1 - 4.3e-09 36.5 0.1 1.2e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 PAH PF02671.16 EDP42894.1 - 4.4e-29 99.8 1.8 8.1e-19 66.9 1.1 2.2 2 0 0 2 2 2 2 Paired amphipathic helix repeat XendoU PF09412.5 EDP42894.1 - 0.52 9.3 0.9 20 4.1 0.0 2.0 2 0 0 2 2 2 0 Endoribonuclease XendoU eIF-1a PF01176.14 EDP42896.1 - 1.2e-26 91.8 0.1 1.7e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YL1 PF05764.8 EDP42896.1 - 6.2 6.3 10.2 10 5.6 7.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein YIF1 PF03878.10 EDP42897.1 - 1.3e-72 243.8 3.7 6.6e-52 176.0 1.4 2.0 2 0 0 2 2 2 2 YIF1 FAE1_CUT1_RppA PF08392.7 EDP42897.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein RNA_pol_Rpb2_1 PF04563.10 EDP42898.1 - 6.7e-30 103.5 0.0 9e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EDP42898.1 - 5.8e-24 83.6 0.0 1.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EDP42898.1 - 1.8e-22 79.7 0.0 2.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EDP42898.1 - 1.7e-19 69.4 0.1 5.6e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_6 PF00562.23 EDP42899.1 - 4.8e-100 335.0 0.0 6.8e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 EDP42899.1 - 4.3e-17 62.1 0.0 2.5e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Nfu_N PF08712.6 EDP42900.1 - 1.3e-31 108.0 0.0 2.8e-31 106.9 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EDP42900.1 - 1.6e-21 75.8 0.2 2.9e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain Peptidase_S10 PF00450.17 EDP42902.1 - 6.6e-28 98.0 0.0 9.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDP42902.1 - 0.029 14.2 1.0 0.069 13.0 0.2 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EDP42903.1 - 3.7e-41 141.6 0.0 4.8e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NOC3p PF07540.6 EDP42904.1 - 6.2e-23 80.8 0.0 1.7e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EDP42904.1 - 1.8e-13 50.2 0.1 1.8e-13 50.2 0.1 3.2 4 0 0 4 4 4 1 CBF/Mak21 family RRM_1 PF00076.17 EDP42905.1 - 1.7e-81 267.8 3.0 6.7e-22 76.9 0.4 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP42905.1 - 1.7e-55 184.8 0.2 3.7e-15 55.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP42905.1 - 7.3e-41 137.8 0.2 2.7e-09 36.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EDP42905.1 - 2e-29 101.0 0.8 2.4e-28 97.6 0.7 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EDP42905.1 - 4.3e-05 23.1 1.7 4.1 7.2 0.2 4.6 3 1 1 4 4 4 1 Limkain b1 CbiG_mid PF11761.3 EDP42905.1 - 0.0015 18.6 0.1 3.3 8.0 0.0 3.0 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EDP42905.1 - 0.0053 16.4 0.5 19 5.1 0.0 4.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF637 PF04830.8 EDP42905.1 - 0.026 14.2 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) GrpE PF01025.14 EDP42906.1 - 9.2e-43 145.6 0.3 1.1e-42 145.3 0.2 1.1 1 0 0 1 1 1 1 GrpE TB2_DP1_HVA22 PF03134.14 EDP42907.1 - 1.6e-28 98.2 7.3 2e-28 97.9 5.0 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Hum_adeno_E3A PF05393.6 EDP42907.1 - 0.35 10.5 2.3 0.41 10.3 1.2 1.4 1 1 0 1 1 1 0 Human adenovirus early E3A glycoprotein KH_1 PF00013.24 EDP42908.1 - 0.00016 21.2 0.3 0.00036 20.1 0.2 1.6 1 0 0 1 1 1 1 KH domain MitMem_reg PF13012.1 EDP42910.1 - 5.3e-35 119.9 0.1 1.1e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EDP42910.1 - 7.9e-27 93.2 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF663 PF04950.7 EDP42911.1 - 8.5e-34 116.8 0.0 8.5e-34 116.8 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDP42911.1 - 9.8e-20 69.8 0.3 2.7e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain DUF3793 PF12672.2 EDP42911.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) DUF663 PF04950.7 EDP42912.1 - 2.7e-38 131.6 0.0 3.3e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF663) Reprolysin_3 PF13582.1 EDP42912.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ORMDL PF04061.9 EDP42913.1 - 4.7e-54 181.6 2.7 5.5e-54 181.4 1.9 1.0 1 0 0 1 1 1 1 ORMDL family DUF2229 PF09989.4 EDP42914.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) SPT6_acidic PF14632.1 EDP42914.1 - 6.9 6.9 17.1 9.5 6.4 5.2 3.2 2 1 0 2 2 2 0 Acidic N-terminal SPT6 LNS2 PF08235.8 EDP42915.1 - 3.2e-70 234.7 0.0 5.1e-70 234.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EDP42915.1 - 9.2e-27 92.9 0.1 8.2e-18 64.0 0.0 2.5 2 0 0 2 2 2 2 lipin, N-terminal conserved region KAT11 PF08214.6 EDP42916.1 - 2.9e-25 89.0 0.0 4.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein FKBP_C PF00254.23 EDP42917.1 - 8.7e-33 112.2 0.0 9.6e-33 112.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RCC1 PF00415.13 EDP42918.1 - 1.3e-53 178.9 9.5 8.4e-11 41.9 0.1 8.7 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDP42918.1 - 5.5e-37 124.6 31.9 3e-08 33.0 0.2 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.6 EDP42918.1 - 0.037 14.0 0.1 13 6.2 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller SPASM PF13186.1 EDP42918.1 - 0.18 12.1 0.0 62 4.0 0.0 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain Linker_histone PF00538.14 EDP42919.1 - 9.9e-11 41.5 0.9 2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family Menin PF05053.8 EDP42919.1 - 0.72 7.9 13.1 0.86 7.6 9.1 1.1 1 0 0 1 1 1 0 Menin DNA_pol_viral_N PF00242.12 EDP42919.1 - 1.5 7.7 19.6 1.8 7.5 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Red1 PF07964.6 EDP42919.1 - 4.9 5.1 19.5 6.1 4.8 13.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Macoilin PF09726.4 EDP42919.1 - 6.3 4.9 22.5 7.2 4.7 15.6 1.0 1 0 0 1 1 1 0 Transmembrane protein tRNA-synt_1 PF00133.17 EDP42920.1 - 4.1e-208 692.2 0.0 1.7e-207 690.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDP42920.1 - 3.9e-34 117.6 0.1 7.4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDP42920.1 - 9.6e-18 63.9 0.5 8.7e-08 31.2 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDP42920.1 - 1.5e-09 37.4 0.2 6e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EDP42920.1 - 0.00098 18.3 0.1 0.54 9.3 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EDP42920.1 - 0.0019 17.1 0.0 0.041 12.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EDP42920.1 - 0.092 11.8 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) IKI3 PF04762.7 EDP42921.1 - 4.7e-231 769.3 0.0 8.4e-231 768.5 0.0 1.3 1 0 0 1 1 1 1 IKI3 family DUF3885 PF13021.1 EDP42921.1 - 0.013 15.1 0.3 0.068 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) TPR_12 PF13424.1 EDP42921.1 - 0.21 11.5 10.6 0.11 12.4 3.5 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ECH PF00378.15 EDP42922.1 - 3.6e-29 101.5 0.0 6e-29 100.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Gly_acyl_tr_C PF08444.5 EDP42923.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region MFS_1 PF07690.11 EDP42924.1 - 7.3e-42 143.3 29.1 7.3e-42 143.3 20.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP42924.1 - 5.4e-15 54.9 24.8 2.5e-14 52.7 17.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter ABC1 PF03109.11 EDP42925.1 - 1.6e-27 95.7 0.0 2.9e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EDP42925.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Spindle_Spc25 PF08234.7 EDP42926.1 - 7.5e-15 54.6 0.0 1.8e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Cortex-I_coil PF09304.5 EDP42926.1 - 3.6e-08 33.4 15.9 6.2e-08 32.6 11.0 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil Spc7 PF08317.6 EDP42926.1 - 0.0018 16.9 3.1 0.0024 16.5 2.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Striatin PF08232.7 EDP42926.1 - 0.012 15.9 13.6 0.02 15.2 9.4 1.2 1 0 0 1 1 1 0 Striatin family APG6 PF04111.7 EDP42926.1 - 0.023 13.7 9.4 0.034 13.2 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EDP42926.1 - 0.048 12.0 5.4 0.072 11.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EDP42926.1 - 0.071 12.7 10.9 0.13 11.9 7.6 1.5 1 0 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 EDP42926.1 - 0.22 11.3 13.3 0.41 10.4 8.9 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EDP42926.1 - 0.28 8.9 2.1 0.29 8.9 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 EDP42926.1 - 0.43 9.8 20.0 0.68 9.1 13.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Syntaxin_2 PF14523.1 EDP42926.1 - 0.81 9.7 7.5 2.2 8.3 4.8 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF883 PF05957.8 EDP42926.1 - 2 8.8 16.2 0.32 11.4 4.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4200 PF13863.1 EDP42926.1 - 3 7.8 19.0 6.1 6.8 12.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2968 PF11180.3 EDP42926.1 - 3.4 6.9 22.7 2.5 7.4 10.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) GAS PF13851.1 EDP42926.1 - 4 6.5 12.5 0.91 8.6 4.9 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EDP42926.1 - 4.2 7.4 14.0 1.3 9.0 5.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 EDP42926.1 - 4.6 7.6 8.9 48 4.3 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EDP42926.1 - 8.3 6.5 8.8 29 4.7 5.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 EDP42926.1 - 8.8 6.3 11.5 3.5 7.6 4.0 2.3 1 1 1 2 2 2 0 FlxA-like protein Pkinase PF00069.20 EDP42927.1 - 2.6e-59 200.4 0.0 7e-59 199.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42927.1 - 1.7e-27 96.1 0.0 3.4e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDP42927.1 - 8.1e-05 21.7 0.0 0.0052 15.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDP42927.1 - 0.045 12.8 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3365 PF11845.3 EDP42927.1 - 0.079 12.7 0.5 0.79 9.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3365) APH PF01636.18 EDP42927.1 - 0.088 12.5 2.4 0.64 9.7 0.0 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family MRP-L47 PF06984.8 EDP42927.1 - 0.17 11.7 1.0 27 4.7 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MAPEG PF01124.13 EDP42928.1 - 9.1e-27 93.2 5.0 1e-26 93.0 3.5 1.0 1 0 0 1 1 1 1 MAPEG family HECT PF00632.20 EDP42929.1 - 1.4e-98 330.0 0.0 1.7e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-UBR PF02207.15 EDP42930.1 - 6.9e-15 54.5 14.3 1.8e-14 53.1 9.9 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EDP42930.1 - 2e-08 33.8 0.0 6.7e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EDP42930.1 - 0.00071 19.3 2.0 0.00071 19.3 1.4 3.8 4 1 1 5 5 5 1 Ring finger domain TRAPP PF04051.11 EDP42931.1 - 4.5e-25 87.9 0.0 5.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Bromodomain PF00439.20 EDP42932.1 - 1.9e-35 120.6 0.3 5.3e-18 64.7 0.0 3.2 2 1 0 2 2 2 2 Bromodomain Sigma70_ner PF04546.8 EDP42932.1 - 0.0023 17.5 2.5 0.0023 17.5 1.7 5.3 5 1 0 5 5 5 1 Sigma-70, non-essential region DUF4604 PF15377.1 EDP42932.1 - 0.0027 17.9 15.4 0.0027 17.9 10.7 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF4604) zf-C2H2 PF00096.21 EDP42933.1 - 1.4e-06 28.2 0.9 0.048 14.0 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDP42933.1 - 6.9e-06 26.0 0.8 0.01 15.9 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EDP42933.1 - 1.6e-05 24.9 0.9 0.021 14.9 0.2 2.1 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EDP42933.1 - 4.5e-05 23.4 1.4 0.0088 16.3 0.0 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger PyrI_C PF02748.10 EDP42933.1 - 0.0016 17.8 1.8 0.13 11.7 0.1 2.1 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EDP42933.1 - 0.0026 17.6 0.8 0.025 14.4 0.0 2.3 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDP42933.1 - 0.0038 17.3 0.3 0.47 10.5 0.1 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) LIM PF00412.17 EDP42933.1 - 0.0086 16.1 0.8 0.017 15.1 0.6 1.5 1 1 0 1 1 1 1 LIM domain zf-H2C2_2 PF13465.1 EDP42933.1 - 0.023 14.9 6.2 0.22 11.9 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C4_ClpX PF06689.8 EDP42933.1 - 0.039 13.4 0.1 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-FCS PF06467.9 EDP42933.1 - 0.083 12.5 3.5 0.64 9.6 0.1 2.2 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.4 EDP42933.1 - 0.12 12.2 0.4 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger domain C1_1 PF00130.17 EDP42933.1 - 0.12 12.1 2.5 0.17 11.6 1.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.1 EDP42933.1 - 0.15 12.3 4.8 10 6.5 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain BIR PF00653.16 EDP42933.1 - 0.17 12.3 1.9 0.24 11.8 1.3 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain DUF4187 PF13821.1 EDP42933.1 - 3.7 7.2 7.1 0.9 9.1 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) Abhydro_lipase PF04083.11 EDP42935.1 - 5.9e-14 51.1 0.0 1.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EDP42935.1 - 4.4e-08 32.9 0.1 1.5e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDP42935.1 - 4e-07 30.1 0.3 1.1e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42935.1 - 1.4e-05 24.8 0.0 5.9e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PUF PF00806.14 EDP42936.1 - 4.8e-44 145.4 4.5 1.5e-08 33.6 0.1 6.3 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat DUF605 PF04652.11 EDP42936.1 - 0.067 12.5 18.2 0.083 12.2 12.6 1.1 1 0 0 1 1 1 0 Vta1 like PUF PF00806.14 EDP42937.1 - 9.3e-20 68.9 0.1 1.8e-08 33.4 0.1 2.3 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat RFC1 PF08519.7 EDP42939.1 - 3.7e-45 153.4 0.0 6.4e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EDP42939.1 - 5.6e-12 45.6 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EDP42939.1 - 3.2e-07 30.6 0.0 6.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDP42939.1 - 9.7e-05 21.2 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDP42939.1 - 0.00035 20.6 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDP42939.1 - 0.0024 17.5 0.0 0.007 16.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EDP42939.1 - 0.0037 16.9 0.0 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDP42939.1 - 0.0043 16.6 0.2 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP42939.1 - 0.0043 17.0 0.3 0.03 14.3 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EDP42939.1 - 0.0078 17.0 0.2 0.05 14.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EDP42939.1 - 0.03 14.2 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDP42939.1 - 0.037 13.7 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EDP42939.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDP42939.1 - 0.07 12.9 1.0 0.27 11.1 0.0 2.5 3 1 1 4 4 4 0 AAA domain Tnp_DNA_bind PF14706.1 EDP42939.1 - 0.078 12.6 0.2 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Transposase DNA-binding Rgp1 PF08737.5 EDP42940.1 - 2.5e-66 224.4 0.0 1.1e-65 222.3 0.0 2.0 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 EDP42940.1 - 0.00052 20.1 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDP42940.1 - 0.00095 19.0 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3426 PF11906.3 EDP42940.1 - 0.042 13.5 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Spo0M PF07070.6 EDP42940.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Sec20 PF03908.8 EDP42941.1 - 2e-15 56.2 1.1 2e-15 56.2 0.8 2.4 2 0 0 2 2 2 1 Sec20 CRCB PF02537.10 EDP42941.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 CrcB-like protein Muted PF14942.1 EDP42941.1 - 9.4 6.1 9.3 2.2 8.1 2.7 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein adh_short PF00106.20 EDP42942.1 - 1.1e-22 80.7 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP42942.1 - 1.3e-09 37.9 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDP42942.1 - 1.8e-08 34.4 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EDP42942.1 - 0.0062 15.7 0.1 0.015 14.4 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 EDP42942.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Arm PF00514.18 EDP42943.1 - 1.1e-55 183.6 24.4 6.2e-12 44.8 0.1 9.7 10 1 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDP42943.1 - 4.4e-17 62.1 8.7 0.00071 19.7 0.3 6.1 2 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EDP42943.1 - 3.3e-12 45.4 14.3 1.1 9.4 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EDP42943.1 - 3.6e-10 40.0 12.4 0.79 10.2 0.1 7.8 7 3 2 9 9 9 4 HEAT-like repeat KAP PF05804.7 EDP42943.1 - 1.8e-06 26.2 0.1 2.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EDP42943.1 - 1.1e-05 24.7 2.2 0.01 14.9 0.3 3.7 1 1 1 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.15 EDP42943.1 - 1.6e-05 23.4 7.5 0.00025 19.5 5.1 2.5 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 EDP42943.1 - 3.4e-05 23.0 5.3 0.11 11.5 0.0 3.4 3 1 1 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.3 EDP42943.1 - 0.0074 16.1 1.6 22 4.9 0.0 3.8 2 1 2 4 4 4 0 V-ATPase subunit H HEAT_PBS PF03130.11 EDP42943.1 - 0.023 15.1 1.5 1.6e+02 3.2 0.0 5.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat FF PF01846.14 EDP42944.1 - 1.8e-14 53.3 9.9 1.9e-05 24.5 0.0 6.2 5 2 0 5 5 5 4 FF domain Abhydrolase_1 PF00561.15 EDP42945.1 - 8.6e-12 45.0 0.1 7.4e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EDP42945.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EDP42945.1 - 0.0033 17.3 0.6 0.0086 15.9 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP42945.1 - 0.072 12.8 0.0 0.71 9.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family TIP120 PF08623.5 EDP42946.1 - 1.3e-38 132.2 0.2 1.3e-37 128.9 0.2 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 EDP42946.1 - 3.4e-06 27.3 45.3 4.5e-05 23.8 0.6 12.3 9 3 3 12 12 12 1 HEAT-like repeat DUF2435 PF10363.4 EDP42946.1 - 8.3e-05 22.4 8.3 2.3 8.1 0.1 5.9 6 1 1 7 7 7 3 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EDP42946.1 - 0.016 14.6 2.1 3.8 6.7 0.0 4.7 4 2 2 6 6 6 0 CLASP N terminal DUF1546 PF07571.8 EDP42946.1 - 0.062 13.4 0.1 0.66 10.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Arm PF00514.18 EDP42946.1 - 0.068 13.0 6.4 0.96 9.3 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EDP42946.1 - 0.15 11.9 1.8 14 5.4 0.0 4.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDP42946.1 - 0.28 11.3 0.0 0.28 11.3 0.0 8.7 11 0 0 11 11 11 0 HEAT repeat WD40 PF00400.27 EDP42947.1 - 0.0015 18.3 0.1 3.8 7.5 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP42947.1 - 0.0026 17.9 0.1 11 6.4 0.0 4.2 4 0 0 4 4 4 2 PQQ-like domain DUF500 PF04366.7 EDP42948.1 - 7.4e-23 80.3 0.0 2.5e-22 78.6 0.0 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF500) RhoGEF PF00621.15 EDP42949.1 - 2e-09 37.5 0.4 4.8e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain Cytochrom_B562 PF07361.6 EDP42949.1 - 0.012 15.9 0.3 2.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Cytochrome b562 EssA PF10661.4 EDP42949.1 - 0.76 9.4 2.5 1.4 8.6 1.7 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SYCE1 PF15233.1 EDP42949.1 - 2.3 8.1 11.2 0.6 10.0 4.1 2.5 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 TSC22 PF01166.13 EDP42949.1 - 8 6.5 13.4 0.28 11.1 0.6 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family BRCT PF00533.21 EDP42950.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDP42950.1 - 2.5e-06 27.2 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 EDP42950.1 - 0.03 14.0 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Peptidase_M24 PF00557.19 EDP42952.1 - 5.5e-36 124.0 0.1 1.9e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDP42952.1 - 3.8e-25 88.8 0.4 1.1e-16 61.4 0.0 2.6 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain DUF4092 PF13322.1 EDP42952.1 - 0.00022 21.0 0.1 0.0004 20.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4092) TPR_11 PF13414.1 EDP42953.1 - 2.4e-17 62.3 10.6 6.5e-15 54.5 4.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDP42953.1 - 6.3e-10 38.2 9.7 0.00077 19.2 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDP42953.1 - 7.2e-07 29.7 10.1 0.0016 19.0 1.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP42953.1 - 2.7e-06 26.7 8.1 0.0008 18.9 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP42953.1 - 8.8e-05 22.8 10.0 0.091 13.4 0.2 4.2 2 1 3 5 5 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EDP42953.1 - 0.00025 21.1 3.8 0.00052 20.0 2.4 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EDP42953.1 - 0.00025 20.8 3.0 2.2 8.2 0.0 3.4 1 1 2 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EDP42953.1 - 0.00046 20.4 9.1 0.0044 17.3 0.5 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP42953.1 - 0.016 15.1 4.8 0.016 15.1 3.4 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP42953.1 - 0.03 14.1 3.4 0.14 11.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDP42953.1 - 0.031 14.2 0.8 0.059 13.3 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EDP42954.1 - 3.6e-41 141.0 0.0 1.5e-25 89.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP42954.1 - 2e-14 53.2 0.0 8.1e-13 48.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDP42954.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP42954.1 - 0.029 13.3 0.0 0.61 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EDP42956.1 - 2.5e-11 43.7 0.3 7.2e-06 25.9 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EDP42956.1 - 5.3e-09 35.6 0.0 5.9e-09 35.4 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDP42956.1 - 3.7e-08 32.6 0.0 1.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDP42956.1 - 1.2e-07 31.2 0.0 0.00082 18.7 0.0 2.0 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 EDP42956.1 - 6.8e-06 25.3 0.0 7.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 EDP42956.1 - 4.9e-05 22.6 0.1 0.00012 21.3 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDP42956.1 - 0.0075 15.8 0.0 0.02 14.4 0.0 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase eIF-3_zeta PF05091.7 EDP42958.1 - 4.6e-166 553.4 0.0 5.6e-166 553.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) VID27 PF08553.5 EDP42959.1 - 1.4e-213 711.4 0.0 1.7e-213 711.1 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein AAA PF00004.24 EDP42960.1 - 5.6e-53 178.6 0.0 4.8e-39 133.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EDP42960.1 - 1.4e-09 37.4 0.2 7.6e-08 31.8 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EDP42960.1 - 3.1e-09 37.0 0.2 0.00082 19.5 0.0 3.4 2 2 1 3 3 2 2 AAA domain AAA_2 PF07724.9 EDP42960.1 - 1.6e-08 34.6 0.0 2.8e-05 24.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDP42960.1 - 3.2e-08 33.4 0.4 0.00096 18.8 0.1 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDP42960.1 - 9.7e-08 32.2 0.1 0.0077 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EDP42960.1 - 1.2e-07 31.3 0.3 0.017 14.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 EDP42960.1 - 1.4e-07 30.5 0.0 0.0059 15.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 EDP42960.1 - 2.5e-07 29.9 0.4 0.023 13.7 0.0 2.6 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDP42960.1 - 9.7e-07 29.6 0.0 0.033 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EDP42960.1 - 1.2e-06 27.8 0.4 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDP42960.1 - 1.4e-06 28.1 0.0 0.058 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDP42960.1 - 2.3e-06 27.1 1.5 0.055 12.8 0.1 3.4 2 2 1 4 4 4 2 AAA domain AAA_14 PF13173.1 EDP42960.1 - 3.9e-06 26.7 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDP42960.1 - 3.9e-06 26.3 0.2 0.043 13.2 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_24 PF13479.1 EDP42960.1 - 1.8e-05 24.4 0.3 0.059 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDP42960.1 - 2e-05 24.9 0.0 0.11 12.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EDP42960.1 - 2.1e-05 24.6 0.0 0.081 13.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EDP42960.1 - 2.5e-05 23.9 0.1 0.042 13.4 0.0 3.0 2 1 0 2 2 2 2 NACHT domain PhoH PF02562.11 EDP42960.1 - 0.00013 21.2 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein KaiC PF06745.8 EDP42960.1 - 0.00019 20.6 0.1 0.017 14.2 0.0 2.5 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.22 EDP42960.1 - 0.0003 21.0 0.1 0.37 11.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 EDP42960.1 - 0.0004 20.0 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EDP42960.1 - 0.0004 20.0 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EDP42960.1 - 0.0005 19.6 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDP42960.1 - 0.00055 19.1 0.1 0.46 9.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.21 EDP42960.1 - 0.00068 19.1 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EDP42960.1 - 0.0011 17.8 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EDP42960.1 - 0.0013 18.7 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EDP42960.1 - 0.0015 18.3 0.1 11 5.6 0.0 4.0 2 2 1 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EDP42960.1 - 0.0024 17.9 0.1 8.1 6.4 0.0 3.6 3 1 0 3 3 2 0 Sigma-54 interaction domain CDC48_N PF02359.13 EDP42960.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain DUF2075 PF09848.4 EDP42960.1 - 0.0034 16.4 0.0 0.9 8.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EDP42960.1 - 0.0042 15.9 0.1 2.7 6.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain UPF0079 PF02367.12 EDP42960.1 - 0.0051 16.4 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EDP42960.1 - 0.022 14.5 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KTI12 PF08433.5 EDP42960.1 - 0.025 13.7 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DAP3 PF10236.4 EDP42960.1 - 0.03 13.2 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 EDP42960.1 - 0.065 12.6 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EDP42960.1 - 0.082 12.4 0.2 4 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EDP42960.1 - 0.088 12.2 0.0 5.1 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain PP2C PF00481.16 EDP42961.1 - 7.4e-31 107.4 0.0 9e-19 67.8 0.0 3.4 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 EDP42961.1 - 0.00038 19.9 0.1 0.41 10.0 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C Cyt-b5 PF00173.23 EDP42962.1 - 9.1e-10 38.2 0.0 1.7e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PCI_Csn8 PF10075.4 EDP42963.1 - 3.2e-30 104.7 0.0 5.2e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDP42963.1 - 2.5e-29 102.3 0.1 3.3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Tektin PF03148.9 EDP42963.1 - 0.1 11.1 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Tektin family HMG_box PF00505.14 EDP42964.1 - 2.2e-20 72.6 8.2 1.9e-10 40.8 0.1 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EDP42964.1 - 7.7e-14 51.8 6.0 1.2e-08 35.2 0.7 2.4 2 0 0 2 2 2 2 HMG-box domain Phe_tRNA-synt_N PF02912.13 EDP42964.1 - 0.14 11.8 0.1 14 5.4 0.0 2.5 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Abhydrolase_2 PF02230.11 EDP42965.1 - 5.2e-10 39.1 0.0 6.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Orexin PF02072.10 EDP42965.1 - 0.058 13.1 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Prepro-orexin MAGE PF01454.14 EDP42966.1 - 7.8e-33 113.4 0.0 1.6e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 MAGE family RNase_T PF00929.19 EDP42967.1 - 1.4e-15 57.9 0.0 2.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EDP42967.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease adh_short PF00106.20 EDP42968.1 - 1e-05 25.4 0.2 0.28 11.0 0.0 3.4 3 1 1 4 4 4 2 short chain dehydrogenase KR PF08659.5 EDP42968.1 - 0.053 13.1 1.0 1.4 8.5 0.0 2.5 2 1 0 2 2 2 0 KR domain Dynamin_N PF00350.18 EDP42969.1 - 4.3e-40 137.2 0.0 8.2e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDP42969.1 - 2.4e-07 29.8 0.1 9.5e-07 27.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Miro PF08477.8 EDP42969.1 - 0.0059 17.1 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP42969.1 - 0.007 16.3 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S3_C PF00189.15 EDP42971.1 - 1.5e-15 57.1 0.1 2.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EDP42971.1 - 1.3e-10 40.7 0.0 2.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 KH domain HABP4_PAI-RBP1 PF04774.10 EDP42972.1 - 5.6e-13 49.3 12.7 5.6e-13 49.3 8.8 2.6 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family PI-PLC-X PF00388.14 EDP42973.1 - 1.1e-52 177.2 0.0 1.9e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDP42973.1 - 1.6e-33 115.1 0.1 3.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EDP42973.1 - 2.2e-06 27.5 0.3 3e-05 23.9 0.0 2.4 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EDP42973.1 - 0.0047 16.7 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 C2 domain EF-hand_8 PF13833.1 EDP42973.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Mg_trans_NIPA PF05653.9 EDP42974.1 - 8.9e-23 80.6 8.0 1.9e-12 46.7 0.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EDP42974.1 - 0.0029 17.8 4.4 0.0029 17.8 3.1 3.0 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Ribosomal_L13 PF00572.13 EDP42976.1 - 4.3e-25 88.2 0.0 9.1e-25 87.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 BBP1_C PF15272.1 EDP42976.1 - 0.0039 16.7 0.3 0.0051 16.3 0.2 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Ribosomal_L32e PF01655.13 EDP42977.1 - 5.4e-44 148.7 0.4 6.3e-44 148.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CRAL_TRIO PF00650.15 EDP42979.1 - 7.8e-19 67.7 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SPA PF08616.5 EDP42980.1 - 4.2e-09 36.0 0.0 8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EDP42980.1 - 4.9e-05 21.9 0.0 0.14 10.5 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 DENN PF02141.16 EDP42980.1 - 0.00045 19.9 0.0 0.0047 16.6 0.0 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain BMF PF15185.1 EDP42980.1 - 2.1 7.6 4.9 4.1 6.6 3.4 1.4 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DEAD PF00270.24 EDP42981.1 - 9.5e-35 119.5 0.2 1.6e-33 115.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP42981.1 - 9.1e-26 89.5 0.2 2e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EDP42981.1 - 0.00063 19.7 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain TIMELESS PF04821.9 EDP42982.1 - 3.2e-44 151.1 0.0 5.2e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Timeless protein DCP1 PF06058.8 EDP42983.1 - 5.2e-23 81.4 0.0 5.7e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family Yippee-Mis18 PF03226.9 EDP42985.1 - 1.8e-21 75.9 0.0 2.8e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cyclin_N PF00134.18 EDP42986.1 - 4.6e-44 149.0 0.1 2.6e-41 140.1 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDP42986.1 - 2.6e-31 107.9 0.1 4.2e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Synapsin_N PF10581.4 EDP42986.1 - 0.79 9.5 2.9 7 6.5 0.1 2.5 2 0 0 2 2 2 0 Synapsin N-terminal JAB PF01398.16 EDP42987.1 - 7.4e-31 106.2 0.5 4.3e-30 103.7 0.2 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDP42987.1 - 5.1e-07 29.2 0.2 2.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EDP42987.1 - 0.083 12.3 0.3 0.75 9.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Aldedh PF00171.17 EDP42988.1 - 4.8e-60 203.2 0.0 9.4e-60 202.2 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_1_2 PF00155.16 EDP42989.1 - 2.8e-43 148.2 0.0 1.8e-42 145.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDP42989.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EDP42989.1 - 0.013 14.1 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FRG2 PF15315.1 EDP42990.1 - 4.1 7.3 10.4 4.9 7.0 7.2 1.0 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 ATP-synt_E PF05680.7 EDP42990.1 - 6.4 6.8 10.9 4.3 7.3 5.6 1.9 1 1 1 2 2 2 0 ATP synthase E chain DUF4557 PF15101.1 EDP42990.1 - 8.2 6.2 8.1 9.3 6.0 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) WD40 PF00400.27 EDP42991.1 - 4e-24 83.5 3.6 4e-08 32.8 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat MMS1_N PF10433.4 EDP42991.1 - 0.0089 14.2 0.0 0.015 13.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4613 PF15390.1 EDP42991.1 - 0.15 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) GTP_EFTU PF00009.22 EDP42992.1 - 3.4e-48 163.5 0.0 5.1e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDP42992.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDP42992.1 - 1.4e-06 28.3 0.1 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDP42992.1 - 9.1e-06 25.4 0.0 2.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EDP42992.1 - 4.5e-05 23.3 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EDP42992.1 - 0.0043 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDP42992.1 - 0.022 13.9 0.0 0.053 12.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EDP42992.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein PLA2_B PF01735.13 EDP42993.1 - 1.5e-146 488.4 0.5 1.9e-146 488.1 0.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain His_Phos_1 PF00300.17 EDP42994.1 - 8.6e-16 58.4 0.0 4.7e-14 52.7 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DAGAT PF03982.8 EDP42995.1 - 5.6e-100 333.8 0.0 6.6e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Cnd2 PF05786.9 EDP42996.1 - 2.7e-131 439.4 14.2 1.4e-129 433.7 9.8 2.7 1 1 0 1 1 1 1 Condensin complex subunit 2 CDP-OH_P_transf PF01066.16 EDP42997.1 - 5.5e-15 55.4 0.3 5.5e-15 55.4 0.2 2.7 2 2 1 3 3 3 1 CDP-alcohol phosphatidyltransferase CNH PF00780.17 EDP42998.1 - 3.4e-29 102.1 0.0 5.8e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EDP42998.1 - 3.1e-28 98.8 0.0 5.8e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EDP42998.1 - 0.0016 18.4 0.0 0.016 15.1 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDP42998.1 - 0.0027 17.9 0.1 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 PH domain Sulfate_transp PF00916.15 EDP42999.1 - 3.4e-77 259.1 3.6 3.4e-77 259.1 2.5 2.1 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDP42999.1 - 3e-30 103.7 3.1 3e-30 103.7 2.1 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDP42999.1 - 2.4e-09 36.6 0.0 8.5e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 STAS domain SNN_transmemb PF09049.5 EDP42999.1 - 0.0017 18.0 0.4 0.0097 15.5 0.3 2.4 1 0 0 1 1 1 1 Stannin transmembrane STAS_2 PF13466.1 EDP42999.1 - 0.0029 17.6 0.1 0.0085 16.0 0.0 1.7 1 0 0 1 1 1 1 STAS domain BRCT PF00533.21 EDP43000.1 - 6.8e-24 83.8 0.0 3.2e-08 33.6 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDP43000.1 - 1.1e-22 79.6 4.3 1.2e-13 50.6 0.1 4.6 4 0 0 4 4 4 3 twin BRCT domain PAT1 PF09770.4 EDP43001.1 - 3.5e-89 300.1 0.2 3.9e-89 299.9 0.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 EDP43002.1 - 5.3e-32 110.9 7.1 5.3e-32 110.9 4.9 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sporozoite_P67 PF05642.6 EDP43002.1 - 0.23 9.2 0.8 0.23 9.2 0.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRP21_like_P PF12230.3 EDP43002.1 - 3 7.2 6.5 2.5 7.5 0.1 2.6 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Sec1 PF00995.18 EDP43003.1 - 3.8e-124 415.4 0.0 7.5e-124 414.4 0.0 1.5 1 1 0 1 1 1 1 Sec1 family K1377 PF15352.1 EDP43003.1 - 0.025 12.5 0.0 0.043 11.7 0.0 1.3 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy DASH_Hsk3 PF08227.6 EDP43004.1 - 1.1e-10 41.4 1.7 1.5e-10 41.0 1.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Snf7 PF03357.16 EDP43004.1 - 0.2 11.0 1.7 0.25 10.6 1.2 1.2 1 1 0 1 1 1 0 Snf7 Aminotran_1_2 PF00155.16 EDP43005.1 - 1.9e-18 66.5 0.0 2.2e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDP43005.1 - 1.4e-09 37.0 0.0 1.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase LSM PF01423.17 EDP43006.1 - 3.3e-18 64.9 0.6 6.1e-18 64.1 0.4 1.4 1 1 0 1 1 1 1 LSM domain BLVR PF06375.6 EDP43006.1 - 0.045 13.5 2.5 0.06 13.1 1.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SM-ATX PF14438.1 EDP43006.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain IU_nuc_hydro PF01156.14 EDP43008.1 - 8.7e-40 136.8 0.0 1.1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CN_hydrolase PF00795.17 EDP43009.1 - 1.9e-13 50.1 0.1 5.8e-13 48.5 0.0 1.8 2 1 0 2 2 2 1 Carbon-nitrogen hydrolase DEAD PF00270.24 EDP43010.1 - 5.5e-44 149.6 0.0 9.8e-43 145.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43010.1 - 1.7e-26 91.8 0.1 3.3e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43010.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Reo_sigmaC PF04582.7 EDP43011.1 - 0.049 12.8 0.2 0.077 12.1 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Ribosomal_L5_C PF00673.16 EDP43012.1 - 4.3e-23 80.8 0.0 6.5e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDP43012.1 - 2.9e-18 65.3 0.3 1.3e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 MKT1_C PF12246.3 EDP43013.1 - 5.7e-62 208.8 0.0 8e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EDP43013.1 - 5.6e-23 81.0 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EDP43013.1 - 2e-07 31.2 0.0 4.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDP43013.1 - 2.9e-07 30.4 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region SARA PF11409.3 EDP43013.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Pkinase PF00069.20 EDP43014.1 - 3e-53 180.6 0.0 2e-52 177.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43014.1 - 2.7e-27 95.4 0.0 5.4e-27 94.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43014.1 - 2.5e-06 26.6 0.0 4.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP43014.1 - 0.00042 20.1 0.1 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP43014.1 - 0.0036 16.3 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDP43014.1 - 0.0078 15.5 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Carn_acyltransf PF00755.15 EDP43015.1 - 3.4e-130 434.9 0.0 6.9e-130 433.9 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase UPF0047 PF01894.12 EDP43016.1 - 6.2e-40 135.7 0.0 6.8e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DuoxA PF10204.4 EDP43016.1 - 0.07 12.1 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor Histidinol_dh PF00815.15 EDP43017.1 - 5.8e-168 558.7 4.5 6.8e-167 555.2 3.1 2.1 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EDP43017.1 - 1.6e-24 85.3 0.8 3.9e-24 84.0 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EDP43017.1 - 1.8e-09 37.7 0.2 1.2e-08 35.0 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EDP43017.1 - 0.0059 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Peptidase_S10 PF00450.17 EDP43018.1 - 7.1e-53 180.2 0.0 8.9e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDP43018.1 - 1.3e-06 28.4 0.5 4.5e-06 26.7 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family YorP PF09629.5 EDP43018.1 - 0.11 12.4 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 YorP protein Maf1 PF09174.5 EDP43019.1 - 1.4e-32 112.9 0.0 1.4e-26 93.4 0.0 2.7 2 1 0 2 2 2 2 Maf1 regulator GTSE1_N PF15259.1 EDP43020.1 - 0.0068 16.3 4.2 0.0068 16.3 2.9 1.9 2 0 0 2 2 2 1 G-2 and S-phase expressed 1 Erythro-docking PF09277.6 EDP43020.1 - 0.049 13.3 2.1 0.15 11.7 1.5 1.9 1 0 0 1 1 1 0 Erythronolide synthase, docking EF-hand_1 PF00036.27 EDP43022.1 - 9.3e-25 84.0 2.7 5.6e-09 34.6 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EDP43022.1 - 4.7e-20 69.6 2.3 4.3e-08 32.3 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EDP43022.1 - 9e-20 69.0 1.6 1.7e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EDP43022.1 - 1.6e-19 69.2 1.9 1e-14 53.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EDP43022.1 - 1.9e-19 69.5 0.1 9.9e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EDP43022.1 - 1.1e-06 28.4 0.1 2.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 EDP43022.1 - 0.00016 21.5 0.0 0.00054 19.8 0.0 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EDP43022.1 - 0.0017 17.8 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 EDP43022.1 - 0.0028 17.6 0.0 0.36 10.8 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EDP43022.1 - 0.011 15.4 0.1 0.033 13.9 0.1 1.9 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Poly_export PF02563.11 EDP43022.1 - 0.022 14.5 0.0 1.7 8.5 0.0 2.7 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein TerB PF05099.8 EDP43022.1 - 0.037 13.7 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Sel1 PF08238.7 EDP43023.1 - 5.3e-44 147.6 17.4 1.3e-06 28.8 0.1 7.4 6 1 1 7 7 7 7 Sel1 repeat TPR_14 PF13428.1 EDP43023.1 - 1.2 9.9 13.9 0.45 11.2 0.5 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat GATA PF00320.22 EDP43024.1 - 0.0014 17.9 10.8 0.03 13.6 0.8 2.6 2 0 0 2 2 2 2 GATA zinc finger OB_NTP_bind PF07717.11 EDP43025.1 - 8.1e-29 99.7 0.0 1.9e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDP43025.1 - 1e-27 96.0 0.1 1e-27 96.0 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP43025.1 - 1.6e-11 43.8 0.0 5.4e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.18 EDP43025.1 - 4.2e-10 39.5 0.1 9.1e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EDP43025.1 - 4.8e-05 22.9 0.1 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDP43025.1 - 0.00034 20.7 0.1 0.0013 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EDP43025.1 - 0.00068 18.6 0.2 0.0022 16.9 0.0 1.9 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.22 EDP43025.1 - 0.0033 17.7 1.2 0.11 12.7 0.1 2.9 2 1 1 3 3 3 1 ABC transporter AAA_19 PF13245.1 EDP43025.1 - 0.0063 16.2 1.1 0.02 14.6 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EDP43025.1 - 0.024 14.6 0.2 0.095 12.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EDP43025.1 - 0.041 13.2 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDP43025.1 - 0.047 13.5 0.0 0.28 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EDP43025.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC PWI PF01480.12 EDP43025.1 - 0.097 12.7 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 PWI domain PAPA-1 PF04795.7 EDP43026.1 - 2.5e-18 66.5 3.3 2.5e-18 66.5 2.3 3.5 3 1 0 3 3 3 1 PAPA-1-like conserved region ThiF PF00899.16 EDP43027.1 - 9.4e-43 145.2 0.1 1.9e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EDP43027.1 - 7.5e-29 99.1 0.1 1.6e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDP43027.1 - 9.4e-20 69.7 5.8 1.6e-19 68.9 4.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EDP43027.1 - 0.00035 20.6 0.0 0.00065 19.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDP43027.1 - 0.011 15.9 0.1 0.055 13.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EDP43027.1 - 0.082 13.3 0.3 1 9.7 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase VEK-30 PF12107.3 EDP43027.1 - 0.1 12.3 0.9 0.24 11.1 0.6 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway MFS_1 PF07690.11 EDP43028.1 - 2.8e-20 72.3 40.3 1.8e-18 66.3 7.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TFIIE_alpha PF02002.12 EDP43029.1 - 1.6e-12 46.8 0.0 3.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EDP43029.1 - 0.094 12.0 1.1 0.22 10.8 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding NMD3 PF04981.8 EDP43030.1 - 1.2e-73 247.1 6.8 1.7e-73 246.6 4.7 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 EDP43030.1 - 0.055 13.3 7.8 0.12 12.2 3.1 2.7 2 1 1 3 3 3 0 Double zinc ribbon rRNA_proc-arch PF13234.1 EDP43031.1 - 2.1e-87 292.7 0.0 2.9e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EDP43031.1 - 2.6e-57 192.9 0.1 5.3e-57 191.9 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDP43031.1 - 2.2e-21 76.0 0.0 1.5e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43031.1 - 8.1e-06 25.6 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43031.1 - 0.038 13.8 0.0 0.32 10.8 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UMP1 PF05348.6 EDP43032.1 - 6.1e-20 71.4 0.1 9.5e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 UCH PF00443.24 EDP43033.1 - 1.6e-39 135.6 0.0 1.9e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP43033.1 - 3.3e-13 49.7 0.0 4.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GCS PF03074.11 EDP43034.1 - 4.6e-143 476.7 0.2 5.9e-143 476.3 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Vps16_N PF04841.8 EDP43035.1 - 1.4e-49 168.7 0.0 5.4e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.7 EDP43035.1 - 6e-44 150.2 0.0 1.8e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region Tubulin_3 PF14881.1 EDP43036.1 - 5.1e-18 65.1 0.0 8.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EDP43036.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain DIM1 PF02966.11 EDP43037.1 - 1.3e-32 112.1 0.1 1.4e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Pterin_4a PF01329.14 EDP43038.1 - 4.3e-25 87.2 0.0 5.9e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ATP-synt_G PF04718.10 EDP43039.1 - 1.7e-20 73.6 0.4 3.3e-20 72.6 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Tape_meas_lam_C PF09718.5 EDP43039.1 - 0.58 10.1 3.9 0.26 11.2 0.6 2.0 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Y_phosphatase2 PF03162.8 EDP43040.1 - 5.4e-59 198.2 0.0 7.7e-59 197.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDP43040.1 - 4.7e-08 33.4 0.0 1.2e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EDP43040.1 - 0.00073 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EDP43040.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HORMA PF02301.13 EDP43041.1 - 1e-44 152.5 0.3 1.2e-44 152.3 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF1649 PF07855.7 EDP43041.1 - 0.049 13.3 0.3 0.13 11.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1649) DUF2110 PF09883.4 EDP43041.1 - 0.076 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) MCM PF00493.18 EDP43042.1 - 3.6e-87 292.2 0.0 5.7e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDP43042.1 - 1.2e-18 67.7 0.2 4.3e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EDP43042.1 - 1.2e-07 31.5 0.1 4.1e-07 29.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDP43042.1 - 3e-07 29.8 0.0 0.00012 21.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDP43042.1 - 3.7e-05 23.3 0.0 0.0013 18.3 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP43042.1 - 0.00072 19.0 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 EDP43042.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EDP43042.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4128 PF13554.1 EDP43042.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function MCM PF00493.18 EDP43043.1 - 3.7e-07 29.2 2.5 4.1e-07 29.1 0.5 1.8 2 1 0 2 2 2 1 MCM2/3/5 family CPSF73-100_C PF11718.3 EDP43044.1 - 6.8e-45 153.0 0.0 3.4e-44 150.7 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EDP43044.1 - 2e-31 108.5 0.0 3.8e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EDP43044.1 - 3.3e-11 42.8 0.1 3.3e-11 42.8 0.1 2.8 2 1 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Orn_Arg_deC_N PF02784.11 EDP43044.1 - 0.13 11.3 0.3 0.32 10.1 0.1 1.7 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain RabGAP-TBC PF00566.13 EDP43045.1 - 4.4e-48 163.5 0.0 6.4e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AalphaY_MDB PF04611.7 EDP43045.1 - 0.058 13.2 2.9 0.049 13.5 0.4 2.0 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region Ribosomal_L37 PF08561.5 EDP43046.1 - 0.014 14.9 13.3 0.11 12.0 9.2 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF4158 PF13700.1 EDP43046.1 - 0.15 11.4 5.4 0.19 11.1 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) FXR1P_C PF12235.3 EDP43046.1 - 1 9.4 8.3 1.1 9.3 5.2 1.5 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal Striatin PF08232.7 EDP43046.1 - 1.5 9.1 9.6 1.8 8.9 6.7 1.0 1 0 0 1 1 1 0 Striatin family ARGLU PF15346.1 EDP43046.1 - 2.9 7.6 18.2 3.4 7.4 12.6 1.0 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Vfa1 PF08432.5 EDP43046.1 - 5.9 6.8 11.2 6.6 6.7 7.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4005 PF13178.1 EDP43046.1 - 8.2 6.7 11.2 28 5.0 7.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) vATP-synt_E PF01991.13 EDP43047.1 - 4.4e-59 199.0 11.4 5.1e-59 198.8 7.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2265 PF10023.4 EDP43047.1 - 0.084 11.9 3.0 0.12 11.4 2.1 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) RRM_1 PF00076.17 EDP43048.1 - 2.5e-13 49.4 0.1 3.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43048.1 - 9.2e-12 44.7 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EDP43048.1 - 1.8e-09 37.6 0.4 3e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 EDP43048.1 - 0.0052 16.6 0.1 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonucleas_3_3 PF14622.1 EDP43049.1 - 5.5e-34 116.8 0.0 8.4e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDP43049.1 - 0.0054 17.1 0.1 0.019 15.3 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Tim17 PF02466.14 EDP43050.1 - 0.012 15.6 0.2 0.07 13.1 0.1 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.22 EDP43051.1 - 3.3e-74 244.6 3.0 8.3e-26 89.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Ribosomal_S13 PF00416.17 EDP43052.1 - 9.8e-40 135.3 1.4 1.2e-39 135.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDP43052.1 - 0.00031 19.4 0.0 0.00034 19.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EDP43052.1 - 0.012 15.6 0.3 0.042 13.9 0.1 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF1822 PF08852.6 EDP43052.1 - 0.019 13.7 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) CPSase_L_D2 PF02786.12 EDP43053.1 - 3.5e-81 271.5 0.1 1.3e-80 269.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EDP43053.1 - 4.3e-63 212.2 0.0 7.6e-63 211.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EDP43053.1 - 9.2e-36 122.2 0.2 4.1e-35 120.2 0.0 2.3 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDP43053.1 - 9e-29 99.5 0.0 2.2e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EDP43053.1 - 5.3e-26 91.7 0.0 9.5e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EDP43053.1 - 2.8e-19 69.5 0.1 5.1e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EDP43053.1 - 1.1e-15 56.9 0.6 2.5e-15 55.8 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EDP43053.1 - 1.9e-15 56.4 0.0 7.7e-15 54.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EDP43053.1 - 1.6e-13 50.0 0.3 4.6e-07 29.4 0.2 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EDP43053.1 - 3.4e-10 39.6 0.0 6.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDP43053.1 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EDP43053.1 - 1.8e-05 24.2 0.1 0.0042 16.4 0.1 2.6 1 1 1 2 2 2 1 HlyD family secretion protein RimK PF08443.6 EDP43053.1 - 4.4e-05 23.0 0.0 0.00024 20.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EDP43053.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EDP43053.1 - 0.00049 20.3 0.0 1 9.7 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 EDP43053.1 - 0.0024 17.0 0.2 0.0042 16.3 0.1 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 EDP43053.1 - 0.053 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EDP43053.1 - 0.065 12.3 0.1 2.2 7.3 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Aminotran_3 PF00202.16 EDP43055.1 - 7.7e-106 353.7 0.0 9.2e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDP43055.1 - 0.0091 14.9 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Fork_head PF00250.13 EDP43056.1 - 5.1e-30 103.3 0.0 1.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Cullin PF00888.17 EDP43057.1 - 4.8e-151 504.2 0.0 2.4e-150 501.9 0.0 1.8 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDP43057.1 - 4.3e-24 84.1 0.2 1.3e-23 82.5 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Pkinase PF00069.20 EDP43058.1 - 4.9e-36 124.2 0.0 7.7e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43058.1 - 2.8e-17 62.6 0.0 6.3e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDP43058.1 - 2.1e-05 23.6 0.0 0.0031 16.5 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.6 EDP43058.1 - 0.35 9.6 0.0 0.53 9.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EDP43058.1 - 0.38 10.4 7.0 0.096 12.4 0.5 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family GATA PF00320.22 EDP43059.1 - 5.9e-16 57.5 6.7 5.9e-16 57.5 4.7 2.8 2 1 1 3 3 3 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EDP43059.1 - 0.0081 15.4 1.4 0.019 14.2 1.0 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 EDP43059.1 - 0.078 12.5 2.4 0.14 11.7 0.4 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger RRN7 PF11781.3 EDP43059.1 - 0.084 12.3 0.7 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Fes1 PF08609.5 EDP43061.1 - 5.6e-19 68.4 0.7 6.8e-19 68.1 0.5 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 TPR_2 PF07719.12 EDP43062.1 - 2.7e-30 101.8 20.4 0.00034 20.3 0.1 10.0 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EDP43062.1 - 5.4e-28 96.4 13.5 1.1e-11 44.1 0.2 7.0 7 0 0 7 7 7 4 TPR repeat TPR_1 PF00515.23 EDP43062.1 - 1.4e-23 81.4 10.0 0.007 15.9 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43062.1 - 6.5e-19 68.0 30.4 8.7e-08 32.6 0.0 8.0 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43062.1 - 2.7e-18 65.6 15.8 8.8e-07 28.7 0.4 8.2 7 1 1 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EDP43062.1 - 5.5e-17 61.6 11.6 9e-10 38.5 0.1 5.8 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EDP43062.1 - 4.9e-16 57.2 0.1 0.018 14.7 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43062.1 - 2.6e-13 49.2 20.8 0.46 11.2 0.0 9.2 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43062.1 - 2.8e-11 43.5 18.6 0.1 12.9 0.4 7.7 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43062.1 - 3.8e-09 36.0 0.9 3.3 8.1 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43062.1 - 1.3e-06 28.4 20.4 1.7 9.2 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDP43062.1 - 2.3e-05 24.1 12.5 0.16 11.9 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP43062.1 - 0.0023 17.6 13.3 2.7 8.0 0.0 7.4 8 1 1 9 9 9 2 Tetratricopeptide repeat APC8 PF04049.8 EDP43062.1 - 0.072 12.8 0.1 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 PPR PF01535.15 EDP43062.1 - 0.11 12.4 0.0 12 6.1 0.0 4.0 4 0 0 4 4 3 0 PPR repeat TPR_4 PF07721.9 EDP43062.1 - 0.14 12.7 22.7 0.15 12.5 0.4 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat HhH-GPD PF00730.20 EDP43063.1 - 1.6e-18 66.9 0.0 3.5e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EDP43063.1 - 2.9e-17 62.1 0.0 1.5e-16 59.8 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 EDP43063.1 - 0.0009 18.8 0.2 0.0027 17.3 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EDP43063.1 - 0.0041 17.2 0.1 0.089 12.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 EDP43063.1 - 0.0047 17.0 7.9 0.011 15.9 5.5 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III DUF2934 PF11154.3 EDP43063.1 - 0.052 12.9 0.7 0.15 11.4 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) LPAM_1 PF08139.7 EDP43064.1 - 2.5 8.4 4.6 4 7.8 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Clat_adaptor_s PF01217.15 EDP43065.1 - 3.2e-45 153.3 0.4 3.1e-33 114.4 0.1 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 EDP43065.1 - 0.038 13.9 0.2 0.058 13.3 0.1 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Arf PF00025.16 EDP43066.1 - 1.5e-42 144.7 0.0 1.7e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDP43066.1 - 0.00033 19.4 0.1 0.0005 18.8 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EDP43066.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDP43066.1 - 0.0048 16.1 0.0 0.0056 15.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EDP43066.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Acyl-CoA_dh_1 PF00441.19 EDP43067.1 - 5.1e-29 101.3 0.8 7.6e-29 100.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDP43067.1 - 2.4e-16 58.9 0.4 4.6e-16 58.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDP43067.1 - 2.9e-13 50.3 0.0 7.7e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDP43067.1 - 7.7e-05 22.9 0.1 0.00015 21.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DAO PF01266.19 EDP43068.1 - 9.3e-52 176.0 0.0 2.1e-51 174.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDP43068.1 - 1.5e-10 41.3 0.0 8.3e-05 22.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDP43068.1 - 1.3e-07 30.8 0.2 4.5e-07 29.0 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDP43068.1 - 6.5e-07 29.2 0.1 2.9e-06 27.2 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDP43068.1 - 1e-06 29.0 0.0 2.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDP43068.1 - 4.2e-06 26.0 0.4 8.6e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EDP43068.1 - 2.6e-05 23.2 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 EDP43068.1 - 3.5e-05 23.5 0.2 6.8e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EDP43068.1 - 0.00029 20.6 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding TrkA_N PF02254.13 EDP43068.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EDP43068.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EDP43068.1 - 0.0017 18.4 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EDP43068.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EDP43068.1 - 0.0073 15.3 0.0 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 EDP43068.1 - 0.023 13.6 0.1 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 EDP43068.1 - 0.036 13.9 0.2 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 EDP43068.1 - 0.04 14.1 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EDP43068.1 - 0.054 12.5 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.12 EDP43068.1 - 0.13 12.6 0.1 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.9 EDP43068.1 - 0.14 10.5 0.6 1.3 7.3 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.19 EDP43068.1 - 0.16 11.0 0.4 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HUN PF08729.5 EDP43069.1 - 3.4e-12 46.0 0.1 3.4e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 EDP43069.1 - 1.3e-07 31.4 0.1 2.8e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HSP70 PF00012.15 EDP43070.1 - 6.7e-265 879.6 13.6 7.6e-265 879.4 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDP43070.1 - 2.6e-19 69.0 0.6 6.3e-17 61.1 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EDP43070.1 - 1.7e-05 24.0 4.1 0.022 13.8 0.1 3.4 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EDP43070.1 - 0.088 12.4 0.0 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain ScpA_ScpB PF02616.9 EDP43070.1 - 0.43 10.1 8.8 0.037 13.6 1.2 2.2 2 0 0 2 2 2 0 ScpA/B protein FtsA PF14450.1 EDP43070.1 - 1.4 8.7 7.3 1.9 8.3 0.7 3.6 3 2 0 3 3 3 0 Cell division protein FtsA CP12 PF02672.10 EDP43070.1 - 1.8 9.0 7.0 1.2 9.6 1.9 2.4 2 0 0 2 2 2 0 CP12 domain Spectrin PF00435.16 EDP43070.1 - 7.4 6.9 11.1 0.36 11.1 1.6 2.8 2 2 1 3 3 3 0 Spectrin repeat Pex2_Pex12 PF04757.9 EDP43071.1 - 1.5e-26 93.2 1.4 2.4e-26 92.5 1.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EDP43071.1 - 5.8e-11 42.0 7.8 1e-10 41.2 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP43071.1 - 2.1e-09 37.2 7.2 4e-09 36.3 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP43071.1 - 2.5e-09 36.6 4.7 4.3e-09 35.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP43071.1 - 4.6e-09 35.8 5.4 7.4e-09 35.1 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDP43071.1 - 1.5e-08 34.1 6.4 2.4e-08 33.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDP43071.1 - 3.4e-07 30.2 3.4 6e-07 29.4 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDP43071.1 - 0.00032 20.3 2.0 0.00078 19.1 0.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDP43071.1 - 0.00079 19.2 3.5 0.00079 19.2 2.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING APP_amyloid PF10515.4 EDP43071.1 - 0.0014 18.8 0.0 0.0047 17.1 0.0 1.8 2 0 0 2 2 1 1 beta-amyloid precursor protein C-terminus zf-RING_6 PF14835.1 EDP43071.1 - 0.0017 18.0 2.7 0.0036 17.0 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EDP43071.1 - 0.0032 17.2 2.1 0.0061 16.3 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDP43071.1 - 0.013 15.0 7.5 0.024 14.2 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EDP43071.1 - 0.087 12.7 3.8 0.18 11.7 2.6 1.5 1 0 0 1 1 1 0 IBR domain Baculo_IE-1 PF05290.6 EDP43071.1 - 0.13 11.9 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 EDP43071.1 - 0.14 11.3 0.3 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger GPI-anchored PF10342.4 EDP43072.1 - 0.0019 18.6 0.4 0.01 16.2 0.3 2.1 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.6 EDP43072.1 - 9.6 4.1 22.2 11 3.9 15.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ras PF00071.17 EDP43073.1 - 6.4e-59 197.9 0.0 7.9e-59 197.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP43073.1 - 1.4e-17 64.2 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP43073.1 - 3.7e-08 32.8 0.0 4.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDP43073.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EDP43073.1 - 0.0036 16.5 0.0 0.0099 15.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EDP43073.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EDP43073.1 - 0.03 13.8 1.7 0.39 10.2 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EDP43073.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GDA1_CD39 PF01150.12 EDP43074.1 - 1.4e-88 297.2 0.0 2.3e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EDP43074.1 - 0.026 13.7 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF4401 PF14351.1 EDP43074.1 - 0.35 9.8 0.2 0.52 9.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Sec6 PF06046.8 EDP43075.1 - 2.2e-111 372.7 0.5 7.8e-111 370.9 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 HTH_31 PF13560.1 EDP43075.1 - 0.0093 16.1 1.0 0.037 14.2 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain zf-CCCH PF00642.19 EDP43076.1 - 0.00019 21.0 1.3 0.00019 21.0 0.9 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 EDP43076.1 - 0.21 11.3 1.5 7.1 6.3 0.1 2.3 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-CCCH_2 PF14608.1 EDP43076.1 - 0.47 10.5 11.0 2.8 8.0 1.2 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type F-box-like_2 PF13013.1 EDP43078.1 - 0.048 13.3 0.0 14 5.4 0.0 2.6 3 0 0 3 3 3 0 F-box-like domain AIRC PF00731.15 EDP43079.1 - 3.5e-64 214.6 0.9 6.9e-64 213.6 0.6 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EDP43079.1 - 2.1e-54 183.4 0.0 3.2e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EDP43079.1 - 9.8e-15 54.7 0.1 7.8e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDP43079.1 - 2.2e-05 23.9 0.0 8.2e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EDP43079.1 - 0.00019 20.2 0.0 0.025 13.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EDP43079.1 - 0.011 15.5 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain CoA_binding_2 PF13380.1 EDP43079.1 - 0.054 13.6 1.1 12 6.0 0.1 3.2 2 1 1 3 3 3 0 CoA binding domain GMC_oxred_C PF05199.8 EDP43080.1 - 1.2e-35 122.9 0.2 2.1e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EDP43080.1 - 5.3e-34 117.7 0.0 8.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DUF3292 PF11696.3 EDP43081.1 - 6.2e-09 34.3 6.0 1.7e-06 26.2 0.6 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 EDP43081.1 - 3e-05 23.5 4.7 0.00016 21.1 0.6 2.4 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 EDP43081.1 - 0.0057 16.2 4.1 0.14 11.7 0.7 2.3 2 0 0 2 2 2 2 Reticulon DUF639 PF04842.7 EDP43081.1 - 2.4 6.2 2.6 32 2.5 0.0 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF639) Arf PF00025.16 EDP43082.1 - 1e-79 265.7 0.1 1.2e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDP43082.1 - 6.2e-14 51.6 0.0 7.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDP43082.1 - 6.8e-13 48.3 0.0 7.3e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDP43082.1 - 5.2e-12 45.1 1.0 7.8e-09 34.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDP43082.1 - 2.9e-11 42.9 0.0 3.3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDP43082.1 - 7.1e-09 36.2 0.0 9.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP43082.1 - 6.5e-06 26.0 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EDP43082.1 - 0.0063 15.6 0.2 0.018 14.1 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EDP43082.1 - 0.018 14.4 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EDP43082.1 - 0.087 12.7 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_pol_I_A49 PF06870.7 EDP43083.1 - 6e-55 186.3 0.0 7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor GntR PF00392.16 EDP43083.1 - 0.079 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF1039 PF06287.6 EDP43083.1 - 0.12 12.2 0.1 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) Methyltransf_28 PF02636.12 EDP43084.1 - 9e-66 221.8 0.0 1.1e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF3_N PF09440.5 EDP43085.1 - 1.3e-37 128.9 2.9 2e-37 128.3 1.3 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EDP43085.1 - 3.2e-10 40.2 0.0 7.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.1 EDP43085.1 - 0.055 13.8 0.1 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L36e PF01158.13 EDP43086.1 - 6.2e-36 122.3 2.9 7e-36 122.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Voldacs PF03517.8 EDP43087.1 - 5.3e-19 68.3 0.1 7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Calcipressin PF04847.7 EDP43088.1 - 2.1e-25 89.3 0.3 5.6e-25 88.0 0.2 1.6 1 1 0 1 1 1 1 Calcipressin DUF500 PF04366.7 EDP43089.1 - 8.5e-39 131.8 0.5 1.4e-38 131.1 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) PGAP1 PF07819.8 EDP43090.1 - 1.2e-57 195.0 0.0 1.7e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDP43090.1 - 3.2e-06 27.2 2.1 1e-05 25.5 1.4 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EDP43090.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EDP43090.1 - 0.00011 22.0 0.1 0.00061 19.5 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EDP43090.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_1 PF00561.15 EDP43090.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDP43090.1 - 0.044 13.3 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 EDP43090.1 - 0.14 11.4 0.1 0.74 9.0 0.0 2.1 3 0 0 3 3 3 0 Lipase (class 2) Pex24p PF06398.6 EDP43091.1 - 5.8 5.6 9.7 1.1 7.9 3.9 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Nop14 PF04147.7 EDP43092.1 - 0.11 10.3 43.3 0.12 10.3 30.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.3 EDP43092.1 - 0.9 8.4 16.8 1.2 8.0 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CENP-T PF15511.1 EDP43092.1 - 5.9 6.0 29.4 7.3 5.7 20.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TIMELESS_C PF05029.8 EDP43092.1 - 9.8 4.9 32.1 11 4.7 22.3 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region Mmp37 PF09139.6 EDP43093.1 - 3.4e-95 318.8 0.0 6.2e-95 317.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 Mur_ligase_M PF08245.7 EDP43094.1 - 0.00033 20.7 0.1 0.15 12.1 0.0 2.6 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 EDP43094.1 - 0.038 14.0 0.0 0.51 10.4 0.0 2.7 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain Slx4 PF09494.5 EDP43094.1 - 0.062 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Slx4 endonuclease Ribosomal_L6e PF01159.14 EDP43095.1 - 1.9e-37 127.8 0.1 2.7e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EDP43095.1 - 0.042 13.7 0.3 0.042 13.7 0.2 2.1 3 0 0 3 3 3 0 Ribosomal protein L6, N-terminal domain Pet127 PF08634.5 EDP43096.1 - 4.5e-106 354.0 0.0 6.2e-106 353.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Glyco_hydro_38C PF07748.8 EDP43096.1 - 0.0027 16.6 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Vma12 PF11712.3 EDP43096.1 - 0.095 12.4 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DER1 PF04511.10 EDP43097.1 - 1.1e-23 83.7 1.5 1.3e-23 83.5 1.1 1.0 1 0 0 1 1 1 1 Der1-like family Exosortase_EpsH PF09721.5 EDP43097.1 - 0.033 13.3 7.3 0.039 13.1 5.1 1.2 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) PRA1 PF03208.14 EDP43097.1 - 0.13 11.6 1.9 0.24 10.7 1.1 1.7 2 0 0 2 2 2 0 PRA1 family protein F-actin_cap_A PF01267.12 EDP43098.1 - 6.6e-71 238.5 4.0 3e-70 236.3 2.8 1.7 1 1 0 1 1 1 1 F-actin capping protein alpha subunit Xpo1 PF08389.7 EDP43099.1 - 1.3e-09 38.0 0.1 7.3e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_C PF08767.6 EDP43099.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal Ferrochelatase PF00762.14 EDP43100.1 - 1.9e-101 339.2 0.0 2.1e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 EDP43100.1 - 0.019 15.1 0.0 3.5 7.8 0.0 2.5 2 1 0 2 2 2 0 CbiX Glyco_trans_4_4 PF13579.1 EDP43100.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.7 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain Tcf25 PF04910.9 EDP43101.1 - 5.6e-76 255.8 0.0 6.9e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SCO1-SenC PF02630.9 EDP43102.1 - 6.8e-58 195.1 0.0 8.7e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EDP43102.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EDP43103.1 - 3e-21 75.5 0.0 4.4e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding PRP1_N PF06424.7 EDP43104.1 - 7.5e-48 162.2 3.5 7.5e-48 162.2 2.4 2.2 3 0 0 3 3 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EDP43104.1 - 2.1e-24 83.7 42.9 0.022 15.3 0.6 15.0 5 3 10 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43104.1 - 2.6e-16 59.6 25.6 0.0088 16.3 1.2 9.7 8 2 4 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43104.1 - 8.4e-15 54.9 35.5 0.00042 20.9 2.5 8.6 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EDP43104.1 - 1.8e-08 33.9 3.1 0.034 13.8 0.1 7.2 8 2 1 9 9 9 1 TPR repeat TPR_12 PF13424.1 EDP43104.1 - 4.6e-07 29.6 17.5 0.042 13.7 0.2 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP43104.1 - 1.8e-05 24.2 5.7 2.9 8.0 0.1 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat NARP1 PF12569.3 EDP43104.1 - 2e-05 23.5 1.9 0.3 9.7 0.0 4.8 3 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 EDP43104.1 - 0.00062 19.3 0.1 1 9.2 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43104.1 - 0.0046 17.0 0.3 4.2 7.8 0.1 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.1 EDP43104.1 - 0.025 13.7 1.5 0.37 9.8 0.0 3.2 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EDP43104.1 - 0.048 14.1 9.9 32 5.2 0.1 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat DEAD PF00270.24 EDP43105.1 - 8.1e-22 77.4 0.0 1.3e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EDP43105.1 - 2.8e-13 50.2 0.6 6.8e-13 49.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EDP43105.1 - 2.5e-11 43.2 0.0 1.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EDP43105.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Malic_M PF03949.10 EDP43106.1 - 6.9e-80 268.2 0.0 8.8e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDP43106.1 - 1.2e-60 204.2 0.0 1.8e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 EDP43106.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EDP43107.1 - 5.7e-45 152.6 0.0 8.6e-45 152.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDP43107.1 - 9.4e-43 145.9 0.0 1.4e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EDP43107.1 - 5.8e-05 21.9 0.0 8.8e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EDP43107.1 - 0.0056 16.9 0.1 0.025 14.8 0.0 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EDP43107.1 - 0.0081 15.2 0.3 0.13 11.3 0.0 2.6 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EDP43107.1 - 0.012 15.5 0.3 0.036 14.0 0.1 1.9 2 1 0 2 2 2 0 NADH(P)-binding Glyco_hydro_4 PF02056.11 EDP43107.1 - 0.079 12.2 0.1 0.24 10.6 0.1 1.8 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase DapB_N PF01113.15 EDP43107.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_C48 PF02902.14 EDP43108.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 EDP43109.1 - 9.5e-12 44.9 0.7 1.5e-11 44.3 0.5 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HD_3 PF13023.1 EDP43110.1 - 4.2e-35 120.9 3.1 4.2e-35 120.9 2.2 2.0 2 0 0 2 2 2 1 HD domain HD PF01966.17 EDP43110.1 - 0.016 15.1 2.8 0.016 15.1 2.0 2.2 2 0 0 2 2 2 0 HD domain Sulfate_transp PF00916.15 EDP43111.1 - 1.8e-17 63.2 5.4 4.9e-12 45.4 0.7 2.6 2 0 0 2 2 2 2 Sulfate transporter family Miro PF08477.8 EDP43112.1 - 1.2e-40 138.7 0.0 1.3e-20 74.1 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EDP43112.1 - 8e-33 113.1 0.0 1.3e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 EDP43112.1 - 7.7e-26 89.1 0.0 1.9e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EDP43112.1 - 1.5e-25 88.7 0.0 2.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.1 EDP43112.1 - 5e-09 35.3 0.4 8.8e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EDP43112.1 - 7.6e-08 31.1 1.0 0.003 16.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDP43112.1 - 1.9e-07 31.0 0.1 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.16 EDP43112.1 - 2.2e-07 30.3 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDP43112.1 - 9e-07 28.8 0.0 0.006 16.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_5 PF13202.1 EDP43112.1 - 2.6e-06 26.5 1.3 0.011 15.1 0.0 2.7 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 EDP43112.1 - 1.3e-05 25.3 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.1 EDP43112.1 - 2.2e-05 23.9 0.9 0.16 11.5 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain pair SRPRB PF09439.5 EDP43112.1 - 2.5e-05 23.5 0.0 0.081 12.1 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EDP43112.1 - 8.6e-05 22.5 0.2 0.099 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 EDP43112.1 - 0.0001 21.8 0.1 0.0092 15.4 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EDP43112.1 - 0.00014 22.1 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDP43112.1 - 0.00019 21.3 1.7 0.4 10.4 0.0 3.0 2 1 0 3 3 3 2 Dynamin family DUF258 PF03193.11 EDP43112.1 - 0.00032 19.9 0.0 0.061 12.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EDP43112.1 - 0.00047 19.8 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain EF-hand_10 PF14788.1 EDP43112.1 - 0.0012 18.4 3.4 0.09 12.4 0.3 2.4 2 0 0 2 2 2 1 EF hand AAA_29 PF13555.1 EDP43112.1 - 0.0012 18.2 0.1 2.1 7.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.22 EDP43112.1 - 0.0023 18.2 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EDP43112.1 - 0.0034 16.8 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDP43112.1 - 0.004 16.8 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EDP43112.1 - 0.004 17.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EDP43112.1 - 0.0048 15.8 0.2 1.5 7.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) cobW PF02492.14 EDP43112.1 - 0.0053 16.2 0.4 6.3 6.2 0.1 3.6 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EDP43112.1 - 0.0073 16.0 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EDP43112.1 - 0.0083 16.1 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EDP43112.1 - 0.011 15.3 0.6 4.9 6.6 0.0 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EDP43112.1 - 0.02 14.3 0.2 0.8 9.1 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 EDP43112.1 - 0.024 14.2 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.4 EDP43112.1 - 0.034 14.1 0.6 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_10 PF12846.2 EDP43112.1 - 0.034 13.5 0.2 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 EDP43112.1 - 0.045 12.7 0.0 1.2 8.0 0.0 2.5 3 0 0 3 3 3 0 Septin Viral_helicase1 PF01443.13 EDP43112.1 - 0.056 12.9 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DAP3 PF10236.4 EDP43112.1 - 0.071 12.0 0.2 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 EDP43112.1 - 0.13 13.0 0.0 21 5.9 0.0 3.3 3 1 0 4 4 2 0 AAA domain AAA_5 PF07728.9 EDP43112.1 - 0.21 11.3 0.5 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HECT PF00632.20 EDP43114.1 - 2.9e-86 289.5 0.0 4.3e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OB_NTP_bind PF07717.11 EDP43115.1 - 9.2e-17 60.9 0.0 2.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDP43115.1 - 1.5e-13 50.6 0.0 3.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP43115.1 - 1.1e-11 44.3 0.0 5.5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP43115.1 - 0.00029 20.3 0.1 0.0025 17.3 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDP43115.1 - 0.029 14.1 0.1 0.08 12.7 0.0 1.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2373 PF10180.4 EDP43116.1 - 4.3e-11 42.1 0.9 4.2e-09 35.8 1.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) HGTP_anticodon2 PF12745.2 EDP43116.1 - 1.3 8.0 5.4 1.7 7.6 3.8 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RRM_6 PF14259.1 EDP43117.1 - 1.2e-37 127.7 0.0 1.6e-17 63.2 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP43117.1 - 5.6e-34 115.5 0.0 4.2e-12 45.5 0.0 5.1 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43117.1 - 1.2e-10 41.0 0.0 0.00036 20.3 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP43117.1 - 7.4e-10 38.4 0.0 4.3e-05 23.1 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EDP43117.1 - 0.024 14.3 0.0 0.48 10.1 0.0 2.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif VWA_2 PF13519.1 EDP43118.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDP43118.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Cullin PF00888.17 EDP43119.1 - 2.4e-162 541.5 5.5 2.4e-162 541.5 3.8 1.3 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDP43119.1 - 1.3e-27 95.3 2.1 4e-27 93.8 1.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 EDP43119.1 - 0.0021 17.5 0.6 0.008 15.7 0.4 2.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_27 PF13463.1 EDP43119.1 - 0.047 14.0 0.3 6.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR_2 PF12802.2 EDP43119.1 - 0.11 12.1 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family Pho88 PF10032.4 EDP43121.1 - 8.1e-13 48.0 0.1 8.1e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pho88 PF10032.4 EDP43122.1 - 2.2e-24 85.7 0.3 2.4e-24 85.6 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.27 EDP43123.1 - 3.8e-13 48.7 15.4 1.9e-07 30.7 0.5 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DPPIV_N PF00930.16 EDP43123.1 - 0.088 11.3 0.7 5.4 5.4 0.4 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Sas10 PF09368.5 EDP43124.1 - 5.5e-24 84.1 2.9 5.5e-24 84.1 2.0 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EDP43124.1 - 3.9e-06 26.9 0.6 1.1e-05 25.4 0.4 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 EDP43125.1 - 5.6e-14 51.9 0.0 5.9e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing EPL1 PF10513.4 EDP43126.1 - 7.4e-06 26.2 0.5 7.4e-06 26.2 0.3 3.6 5 1 0 5 5 5 1 Enhancer of polycomb-like Tom22 PF04281.8 EDP43127.1 - 1.8e-43 147.3 0.3 2.1e-43 147.1 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SDA1 PF05285.7 EDP43127.1 - 0.0045 16.3 1.1 0.0045 16.3 0.8 1.1 1 0 0 1 1 1 1 SDA1 YL1 PF05764.8 EDP43127.1 - 7.3 6.1 9.2 9.8 5.7 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Na_H_Exchanger PF00999.16 EDP43129.1 - 2.7e-16 59.1 5.7 3.2e-16 58.8 4.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CCDC-167 PF15188.1 EDP43129.1 - 2.4 8.1 5.6 20 5.1 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 dCMP_cyt_deam_1 PF00383.17 EDP43130.1 - 1.6e-09 37.3 0.1 2.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SET PF00856.23 EDP43130.1 - 3.3e-06 27.4 0.0 9.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 SET domain RXT2_N PF08595.6 EDP43131.1 - 9.6 5.9 9.5 29 4.4 6.6 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoporin_FG PF13634.1 EDP43132.1 - 0.00067 19.8 40.2 0.0029 17.8 13.1 7.3 2 2 4 6 6 6 3 Nucleoporin FG repeat region CK_II_beta PF01214.13 EDP43133.1 - 3.1e-54 183.2 0.0 3.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PHD PF00628.24 EDP43134.1 - 5.2e-05 22.8 11.8 0.0001 21.9 8.2 1.5 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 EDP43134.1 - 0.0013 18.6 0.2 0.0036 17.1 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 DDT PF02791.12 EDP43134.1 - 0.026 14.2 1.3 0.054 13.2 0.9 1.4 1 0 0 1 1 1 0 DDT domain Baculo_ME53 PF06061.6 EDP43134.1 - 0.72 8.7 2.8 5.4 5.9 0.1 2.1 1 1 1 2 2 2 0 Baculoviridae ME53 Prok-RING_1 PF14446.1 EDP43134.1 - 8.8 6.1 12.1 0.11 12.2 2.7 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Borrelia_P83 PF05262.6 EDP43134.1 - 9.1 4.4 10.5 13 3.8 7.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 EDP43135.1 - 3.3e-68 229.6 0.0 5.3e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43135.1 - 2.7e-29 102.0 0.0 4.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3449 PF11931.3 EDP43135.1 - 0.035 13.6 2.3 0.89 9.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) APH PF01636.18 EDP43135.1 - 0.083 12.6 0.1 0.083 12.6 0.1 2.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family HARP PF07443.8 EDP43136.1 - 0.059 12.7 0.3 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) Tyr-DNA_phospho PF06087.7 EDP43137.1 - 8.5e-18 64.1 0.0 9.4e-18 64.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EDP43137.1 - 0.00013 21.7 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PPR_3 PF13812.1 EDP43139.1 - 0.038 14.2 2.7 31 5.1 0.0 4.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Abhydrolase_6 PF12697.2 EDP43141.1 - 3.7e-05 23.7 0.0 9.8e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP43141.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family POPLD PF08170.7 EDP43142.1 - 1.8e-15 56.5 0.0 3.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.6 EDP43142.1 - 5.1e-13 49.0 0.6 1e-12 48.1 0.4 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 BATS PF06968.8 EDP43142.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain adh_short PF00106.20 EDP43143.1 - 0.00038 20.4 0.1 0.016 15.0 0.0 2.5 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EDP43143.1 - 0.0049 16.5 0.2 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF1681 PF07933.9 EDP43144.1 - 2.1e-34 118.3 0.0 2.5e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SSV1_ORF_D-335 PF07935.6 EDP43144.1 - 0.0032 17.1 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 ORF D-335-like protein DUF1983 PF09327.6 EDP43144.1 - 0.056 13.4 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1983) WD40 PF00400.27 EDP43145.1 - 2.7e-18 65.0 5.4 7.1e-05 22.5 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat NAD_binding_10 PF13460.1 EDP43146.1 - 1.4e-20 74.0 0.0 2.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDP43146.1 - 2.6e-14 53.0 0.0 3.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EDP43146.1 - 2.9e-14 52.4 0.0 2.2e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDP43146.1 - 5.9e-14 52.0 0.0 9.8e-13 48.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDP43146.1 - 1.4e-12 47.1 0.8 3.4e-06 26.1 0.2 3.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EDP43146.1 - 1.8e-12 46.7 0.0 2.3e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EDP43146.1 - 0.0015 17.5 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EDP43146.1 - 0.0089 15.9 0.0 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP43146.1 - 0.11 12.2 0.0 0.41 10.2 0.0 1.7 1 1 0 1 1 1 0 KR domain Mit_KHE1 PF10173.4 EDP43147.1 - 1.1e-51 175.3 3.1 1.6e-51 174.8 2.2 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Glyco_hydro_16 PF00722.16 EDP43148.1 - 1e-08 34.6 0.0 2.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_2b PF00587.20 EDP43149.1 - 3.6e-28 98.2 0.1 5.3e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP43149.1 - 1.8e-05 24.5 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDP43149.1 - 0.0055 15.5 0.1 0.0089 14.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Peptidase_M22 PF00814.20 EDP43150.1 - 6.3e-77 258.6 0.0 1.3e-76 257.6 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family Helicase_C PF00271.26 EDP43151.1 - 2.2e-14 53.0 0.0 3.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP43151.1 - 1.2e-05 24.8 0.0 0.00015 21.2 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase DXP_redisom_C PF08436.7 EDP43151.1 - 0.11 12.3 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal HLH PF00010.21 EDP43152.1 - 1.3e-17 63.2 1.7 4.2e-17 61.5 1.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med21 PF11221.3 EDP43153.1 - 3e-09 36.9 0.3 5.1e-09 36.2 0.2 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex GAT PF03127.9 EDP43153.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 GAT domain DUF3135 PF11333.3 EDP43153.1 - 0.14 12.3 0.1 0.39 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Endosulfine PF04667.12 EDP43154.1 - 6.2e-20 70.9 0.0 9.8e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Porin_3 PF01459.17 EDP43155.1 - 5.8e-59 199.6 0.3 6.5e-59 199.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin AP2 PF00847.15 EDP43156.1 - 0.11 12.6 0.3 0.29 11.3 0.2 1.7 1 0 0 1 1 1 0 AP2 domain CPSF_A PF03178.10 EDP43157.1 - 3.4e-40 138.0 0.0 1.3e-39 136.1 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EDP43157.1 - 7.6e-12 44.1 0.0 1.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term TPR_11 PF13414.1 EDP43158.1 - 3.8e-12 45.6 11.3 4.1e-08 32.7 2.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDP43158.1 - 8.8e-10 37.7 3.2 2.8e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP43158.1 - 1.6e-07 30.7 6.5 0.0014 18.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43158.1 - 5.9e-06 26.8 3.3 5.9e-06 26.8 2.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43158.1 - 4.5e-05 23.7 1.2 0.0001 22.5 0.6 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43158.1 - 0.00013 21.8 0.2 0.045 13.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43158.1 - 0.00021 21.6 1.7 0.0014 19.0 0.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDP43158.1 - 0.0071 16.4 4.9 0.086 12.9 1.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDP43158.1 - 0.01 15.5 1.2 0.031 14.0 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43158.1 - 0.012 15.5 1.7 0.012 15.5 1.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 EDP43158.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EDP43158.1 - 0.038 13.8 0.6 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43158.1 - 0.96 10.0 6.5 13 6.5 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_11 PF13086.1 EDP43159.1 - 5.5e-65 219.2 0.0 9.9e-65 218.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EDP43159.1 - 3.1e-60 203.0 0.0 5e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 EDP43159.1 - 3.3e-20 71.7 0.0 5.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 EDP43159.1 - 1.5e-10 40.7 0.7 6.1e-10 38.7 0.5 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDP43159.1 - 5e-10 39.2 0.1 1e-05 25.2 0.0 3.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EDP43159.1 - 7.8e-08 32.1 0.2 0.064 12.7 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDP43159.1 - 0.00019 21.5 0.4 0.061 13.4 0.0 3.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP43159.1 - 0.0045 17.0 1.0 0.012 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.16 EDP43159.1 - 0.0069 15.7 0.0 0.17 11.1 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EDP43159.1 - 0.014 14.8 0.2 0.05 13.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EDP43159.1 - 0.026 14.6 0.0 0.08 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EDP43159.1 - 0.095 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 EDP43159.1 - 0.29 11.9 0.0 0.86 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain C1_1 PF00130.17 EDP43160.1 - 2.8e-20 71.7 21.8 7.3e-11 41.6 3.3 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EDP43160.1 - 5.9e-07 29.1 4.6 1.2e-06 28.1 3.2 1.5 1 0 0 1 1 1 1 Hr1 repeat FYVE_2 PF02318.11 EDP43160.1 - 0.37 10.6 14.3 1.4 8.8 2.4 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.20 EDP43161.1 - 1.7e-66 224.0 0.0 2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43161.1 - 1.2e-36 126.1 0.0 1.5e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43161.1 - 0.00029 19.9 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Ribosomal_S19e PF01090.14 EDP43162.1 - 3.1e-45 153.0 0.0 3.5e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RXT2_N PF08595.6 EDP43162.1 - 0.0057 16.4 1.8 0.0067 16.2 1.2 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal Bd3614_N PF14442.1 EDP43162.1 - 0.023 14.6 0.9 0.034 14.1 0.6 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Nucleoplasmin PF03066.10 EDP43162.1 - 0.075 12.5 8.8 0.086 12.3 6.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EDP43162.1 - 3.9 7.0 9.2 4.8 6.7 6.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EDP43162.1 - 4.4 5.2 6.1 4.8 5.0 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_5 PF13893.1 EDP43163.1 - 1.4e-10 40.8 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP43163.1 - 2.8e-09 36.4 0.0 8.6e-09 34.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43163.1 - 9.8e-06 25.4 0.0 4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PYST-C1 PF09690.5 EDP43163.1 - 0.13 11.9 1.8 0.26 10.9 1.2 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) RhoGAP PF00620.22 EDP43164.1 - 4e-09 36.2 0.1 8.5e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EDP43164.1 - 0.021 14.9 0.3 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RIO1 PF01163.17 EDP43165.1 - 6e-70 234.4 0.0 1.2e-69 233.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EDP43165.1 - 0.00051 19.1 3.0 0.0052 15.8 1.9 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDP43165.1 - 0.0047 16.1 0.1 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 EDP43165.1 - 0.031 13.8 0.4 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EDP43165.1 - 0.041 13.6 3.9 0.28 10.8 0.6 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 EDP43166.1 - 1.2e-35 123.2 0.1 1.5e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain vATP-synt_AC39 PF01992.11 EDP43167.1 - 2.2e-100 336.0 0.0 2.5e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit HA2 PF04408.18 EDP43168.1 - 2.9e-18 65.7 2.0 3.6e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP43168.1 - 6.5e-13 48.3 0.0 1.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDP43168.1 - 5.1e-09 35.9 0.0 2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EDP43168.1 - 4.8e-07 29.4 0.0 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDP43168.1 - 1.1e-06 28.8 0.0 4.3e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EDP43168.1 - 0.076 13.3 0.0 0.076 13.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDP43168.1 - 0.085 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC UDG PF03167.14 EDP43169.1 - 2.2e-18 66.1 0.0 4.4e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Yos1 PF08571.5 EDP43171.1 - 1.7e-20 72.8 1.5 2.6e-20 72.2 1.1 1.3 1 1 0 1 1 1 1 Yos1-like Hydrolase_6 PF13344.1 EDP43172.1 - 3e-19 68.7 0.0 6.2e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDP43172.1 - 3.8e-07 29.7 0.0 8.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDP43172.1 - 0.039 14.3 0.0 11 6.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDP43172.1 - 0.1 12.8 0.0 1.3 9.2 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase OPT PF03169.10 EDP43174.1 - 5.4e-64 216.7 8.7 6e-64 216.5 6.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Colicin_V PF02674.11 EDP43174.1 - 0.0091 15.8 1.8 2.1 8.1 0.1 2.5 2 0 0 2 2 2 2 Colicin V production protein SNARE_assoc PF09335.6 EDP43174.1 - 0.41 10.8 7.2 0.81 9.8 0.6 3.2 1 1 2 3 3 3 0 SNARE associated Golgi protein OPT PF03169.10 EDP43175.1 - 5.1e-80 269.6 23.1 5.8e-80 269.4 16.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cohesin_HEAT PF12765.2 EDP43178.1 - 6.4e-11 41.9 4.5 3.2e-10 39.7 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EDP43178.1 - 0.00013 21.7 3.0 4.4 7.6 0.1 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 EDP43178.1 - 0.016 15.4 1.4 0.45 10.8 0.4 3.2 1 1 2 3 3 3 0 HEAT repeats Cnd1 PF12717.2 EDP43178.1 - 0.024 14.4 0.8 0.46 10.3 0.1 2.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.2 EDP43179.1 - 3.8e-48 163.6 3.3 6.2e-48 162.9 0.3 2.4 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus DUF3452 PF11934.3 EDP43179.1 - 0.16 11.2 0.6 0.82 8.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) HEAT_2 PF13646.1 EDP43179.1 - 0.88 9.8 5.8 2.3 8.5 2.7 2.7 2 1 1 3 3 3 0 HEAT repeats Chitin_synth_2 PF03142.10 EDP43180.1 - 4.2e-231 767.9 0.0 5.4e-231 767.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EDP43180.1 - 5.5e-18 65.6 0.0 9.5e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EDP43180.1 - 4.8e-15 55.0 0.3 8.2e-14 51.1 0.2 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EDP43180.1 - 4.5e-12 45.6 0.0 1.5e-07 31.0 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EDP43180.1 - 5.2e-12 45.8 2.8 5.2e-12 45.8 1.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EDP43180.1 - 4.3e-05 23.2 0.0 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDP43180.1 - 6.4e-05 22.3 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pkinase PF00069.20 EDP43181.1 - 1.3e-72 244.0 0.0 1.6e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43181.1 - 3.2e-32 111.6 0.0 4.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDP43181.1 - 0.001 18.1 0.2 0.0022 17.0 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP43181.1 - 0.0023 17.7 0.5 0.058 13.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP43181.1 - 0.0047 15.9 0.0 0.018 14.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like YukC PF10140.4 EDP43181.1 - 0.058 11.9 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Sel1 PF08238.7 EDP43182.1 - 3.9e-10 40.0 13.7 5.4e-07 30.0 0.1 6.3 6 0 0 6 6 6 2 Sel1 repeat PIH1 PF08190.7 EDP43182.1 - 0.0012 18.3 5.8 0.0022 17.5 4.0 1.4 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 TPR_2 PF07719.12 EDP43182.1 - 0.0013 18.4 0.1 0.043 13.7 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PV-1 PF06637.6 EDP43182.1 - 0.32 9.5 10.6 0.54 8.7 7.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) AAA_13 PF13166.1 EDP43182.1 - 5.4 5.3 6.6 7.7 4.8 4.6 1.1 1 0 0 1 1 1 0 AAA domain eIF-5a PF01287.15 EDP43183.1 - 2.5e-27 94.5 0.4 3.3e-27 94.2 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold HLH PF00010.21 EDP43184.1 - 1.7e-13 50.0 0.1 3.2e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MCC-bdg_PDZ PF10506.4 EDP43184.1 - 5.1 7.0 6.8 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Telomere_reg-2 PF10193.4 EDP43185.1 - 1.4e-26 92.9 0.0 2.9e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein NAD_binding_7 PF13241.1 EDP43186.1 - 1.7e-29 102.0 0.0 2.8e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EDP43186.1 - 3.3e-25 87.1 0.3 5.2e-25 86.5 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EDP43186.1 - 1.6e-10 39.7 0.0 2.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EDP43186.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pil1 PF13805.1 EDP43187.1 - 3.1e-16 59.3 1.6 7e-16 58.1 1.1 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 Ribonuc_P_40 PF08584.6 EDP43188.1 - 8.3e-39 133.2 0.0 5.6e-23 81.3 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease P 40kDa (Rpp40) subunit TEA PF01285.13 EDP43189.1 - 2.1e-33 116.1 1.2 2.1e-33 116.1 0.8 3.9 3 1 0 3 3 3 1 TEA/ATTS domain family Sec1 PF00995.18 EDP43190.1 - 4.3e-113 378.9 0.0 5.3e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3182 PF11379.3 EDP43190.1 - 0.03 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) tRNA-synt_1e PF01406.14 EDP43191.1 - 3.3e-122 407.3 0.0 1.3e-121 405.3 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EDP43191.1 - 4.8e-10 38.6 0.2 4.6e-05 22.2 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDP43191.1 - 6.4e-08 31.0 0.3 0.0014 16.7 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 EDP43191.1 - 5.6e-05 21.9 0.3 0.0042 15.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.6 EDP43191.1 - 0.00012 22.2 0.0 0.0008 19.6 0.0 2.4 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.13 EDP43191.1 - 0.017 13.8 0.0 3.4 6.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) EGL-1 PF11430.3 EDP43191.1 - 0.59 9.7 2.6 1.6 8.3 1.8 1.6 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 TetR_C PF02909.12 EDP43191.1 - 0.77 9.4 5.2 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain Exo_endo_phos PF03372.18 EDP43192.1 - 1.6e-22 80.6 0.0 3e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LUC7 PF03194.10 EDP43193.1 - 1e-53 182.4 2.9 5.7e-53 180.0 0.9 1.9 1 1 1 2 2 2 1 LUC7 N_terminus Mnd1 PF03962.10 EDP43193.1 - 0.0038 16.9 0.9 0.005 16.5 0.6 1.3 1 0 0 1 1 1 1 Mnd1 family Mod_r PF07200.8 EDP43193.1 - 0.017 15.0 3.1 0.031 14.2 2.2 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 EDP43193.1 - 0.017 14.1 3.6 0.023 13.7 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 EDP43193.1 - 0.047 13.1 3.5 0.07 12.5 2.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF342 PF03961.8 EDP43193.1 - 0.064 11.6 1.0 0.078 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FliJ PF02050.11 EDP43193.1 - 0.071 13.1 8.2 7.8 6.5 5.4 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein AAA_13 PF13166.1 EDP43193.1 - 0.1 11.0 3.9 2 6.7 2.5 1.9 1 1 1 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EDP43193.1 - 0.15 9.8 0.6 0.17 9.6 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.5 EDP43193.1 - 0.3 11.2 3.5 6.1 7.0 2.1 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Seryl_tRNA_N PF02403.17 EDP43193.1 - 1.8 8.5 9.4 1 9.3 0.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Thymidylate_kin PF02223.12 EDP43194.1 - 1.7e-42 144.9 0.0 2.3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EDP43194.1 - 0.00059 19.8 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Abhydrolase_5 PF12695.2 EDP43194.1 - 0.00079 19.1 0.0 0.0044 16.7 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_33 PF13671.1 EDP43194.1 - 0.0019 18.0 0.0 0.0058 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain FSH1 PF03959.8 EDP43194.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PRK PF00485.13 EDP43194.1 - 0.052 13.1 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EDP43194.1 - 0.13 12.4 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EDP43194.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CSTF2_hinge PF14327.1 EDP43195.1 - 2.2e-28 98.1 1.9 2.2e-28 98.1 1.3 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EDP43195.1 - 6.3e-09 34.9 8.5 6.3e-09 34.9 5.9 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal DUF4414 PF14377.1 EDP43195.1 - 0.13 12.1 1.6 5.4 6.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Prefoldin_2 PF01920.15 EDP43196.1 - 7.3e-07 28.9 10.7 0.0017 18.0 0.2 2.0 2 0 0 2 2 2 2 Prefoldin subunit Tropomyosin PF00261.15 EDP43196.1 - 0.11 11.6 7.7 0.037 13.1 2.4 1.9 2 0 0 2 2 2 0 Tropomyosin Myosin_tail_1 PF01576.14 EDP43196.1 - 0.3 8.7 9.2 0.021 12.5 2.8 1.5 2 0 0 2 2 2 0 Myosin tail Kinetocho_Slk19 PF12709.2 EDP43196.1 - 0.67 10.0 6.3 0.21 11.6 1.6 2.0 2 0 0 2 2 2 0 Central kinetochore-associated TPR_MLP1_2 PF07926.7 EDP43196.1 - 4.5 7.0 11.0 4.5 7.0 4.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein B56 PF01603.15 EDP43197.1 - 1e-165 551.2 7.7 1.3e-165 551.0 5.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec66 PF09802.4 EDP43198.1 - 8.8e-31 106.7 0.2 1e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 CK_II_beta PF01214.13 EDP43199.1 - 3e-33 114.8 0.0 3.5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Transket_pyr PF02779.19 EDP43200.1 - 4.6e-49 166.3 0.1 6.5e-49 165.8 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDP43200.1 - 2.3e-38 130.9 0.0 4.8e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Pyrophosphatase PF00719.14 EDP43201.1 - 9.1e-53 177.8 0.1 1.3e-52 177.4 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase peroxidase PF00141.18 EDP43202.1 - 1.5e-47 162.0 0.0 2.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.1 EDP43202.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Glyco_transf_49 PF13896.1 EDP43202.1 - 0.17 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Arrestin_C PF02752.17 EDP43203.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain E1-E2_ATPase PF00122.15 EDP43205.1 - 1.1e-65 220.9 2.5 1.1e-65 220.9 1.7 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDP43205.1 - 3.8e-48 163.4 5.0 9.8e-48 162.0 2.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDP43205.1 - 9.1e-35 121.0 0.0 6.4e-34 118.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP43205.1 - 9.7e-18 63.9 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDP43205.1 - 3.5e-16 59.9 0.0 9.4e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDP43205.1 - 8.5e-10 38.6 1.2 1.8e-07 31.0 1.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase L31 PF09784.4 EDP43206.1 - 1.4e-36 124.6 0.3 1.6e-36 124.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 F_bP_aldolase PF01116.15 EDP43207.1 - 2e-100 335.5 0.0 2.3e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II GLTP PF08718.6 EDP43208.1 - 5.3e-38 130.3 0.0 7.8e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fasciclin PF02469.17 EDP43209.1 - 5.6e-54 181.5 1.3 4.3e-12 46.1 0.0 6.2 5 2 0 5 5 5 5 Fasciclin domain Radical_SAM PF04055.16 EDP43210.1 - 7e-16 58.8 0.1 2.6e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EDP43210.1 - 4.5e-10 39.4 0.0 1.4e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDP43210.1 - 0.01 15.9 0.1 0.066 13.3 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDP43210.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Myotub-related PF06602.9 EDP43211.1 - 6e-06 25.2 0.0 6.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Myotub-related PF06602.9 EDP43212.1 - 1.6e-106 356.0 0.2 2.1e-106 355.7 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EDP43212.1 - 8.8e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EDP43212.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EDP43212.1 - 0.027 14.7 0.1 0.078 13.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family LRR_6 PF13516.1 EDP43213.1 - 1.2e-13 49.5 11.4 0.19 11.9 0.1 8.3 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 EDP43213.1 - 2.6e-08 33.3 14.9 0.044 13.4 1.8 6.4 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP43213.1 - 8.9e-05 22.1 14.8 0.18 11.5 0.8 5.5 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EDP43213.1 - 0.0016 18.1 13.0 6.6 7.1 0.6 7.5 7 1 2 9 9 9 1 Leucine Rich Repeat CobT PF06213.7 EDP43213.1 - 0.33 10.0 14.1 2.7 7.0 9.9 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 EDP43213.1 - 1.2 8.6 16.1 2.1 7.8 11.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EDP43213.1 - 9.3 5.3 11.9 17 4.4 8.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Lactamase_B_2 PF12706.2 EDP43214.1 - 1.8e-12 47.2 1.6 2.3e-12 46.8 0.4 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDP43214.1 - 1e-10 41.6 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily WD40 PF00400.27 EDP43215.1 - 2.2e-28 97.0 5.6 1.1e-07 31.4 0.0 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EDP43215.1 - 9.5e-06 25.2 0.6 0.00041 19.8 0.5 3.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EDP43215.1 - 1e-05 25.6 0.4 0.14 12.4 0.0 4.0 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EDP43215.1 - 0.35 10.5 2.8 8.6 6.0 0.1 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat FMO-like PF00743.14 EDP43216.1 - 7.7e-19 67.2 0.0 1.2e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDP43216.1 - 1.6e-05 23.9 0.0 0.0001 21.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDP43216.1 - 2.4e-05 24.5 0.0 7.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP43217.1 - 9.7e-10 38.3 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDP43217.1 - 1.2e-07 31.6 0.0 1.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDP43217.1 - 3.4e-06 27.2 0.0 3.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDP43217.1 - 6.8e-05 22.8 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDP43217.1 - 0.00069 18.7 0.1 0.00082 18.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family FMO-like PF00743.14 EDP43217.1 - 0.0012 17.0 0.0 0.0015 16.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like FAD_oxidored PF12831.2 EDP43217.1 - 0.0023 17.0 0.2 0.0028 16.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EDP43217.1 - 0.0032 16.4 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDP43217.1 - 0.0033 15.9 0.5 0.004 15.6 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EDP43217.1 - 0.037 13.0 0.1 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EDP43217.1 - 0.053 12.4 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDP43217.1 - 0.061 12.1 0.7 0.068 12.0 0.5 1.1 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 EDP43217.1 - 0.071 12.1 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EDP43217.1 - 0.17 10.4 0.3 0.19 10.2 0.2 1.0 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EDP43217.1 - 0.26 10.1 0.7 0.29 9.9 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.20 EDP43218.1 - 1.3e-32 113.0 0.0 1.7e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43218.1 - 8.3e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP43218.1 - 0.00098 18.9 0.0 1 9.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.10 EDP43219.1 - 5.8e-19 67.1 0.5 5.8e-19 67.1 0.3 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DNA_pol_phi PF04931.8 EDP43220.1 - 9.2e-64 215.5 13.4 8.8e-50 169.3 8.0 2.3 2 0 0 2 2 2 2 DNA polymerase phi DUF1117 PF06547.7 EDP43220.1 - 0.59 10.2 5.8 0.6 10.2 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) RRN3 PF05327.6 EDP43220.1 - 0.76 7.8 24.4 2.7 6.0 10.0 3.7 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 EDP43220.1 - 5.5 4.5 5.5 8.6 3.9 3.8 1.2 1 0 0 1 1 1 0 Ycf1 Rhodanese PF00581.15 EDP43221.1 - 1e-11 45.1 0.0 2.6e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain PUF PF00806.14 EDP43223.1 - 5.8e-24 82.1 0.0 0.00047 19.4 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EDP43223.1 - 3.5e-11 42.5 0.0 1.1e-05 24.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43223.1 - 2.3e-09 36.9 0.0 3e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43223.1 - 4e-08 33.1 0.0 0.0066 16.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP43224.1 - 2.5e-18 65.4 0.0 8.9e-13 47.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43224.1 - 3.4e-17 62.1 0.0 3.6e-11 42.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43224.1 - 1.3e-11 44.1 0.0 3.2e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 EDP43225.1 - 1.1e-05 25.4 8.7 0.0079 16.4 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP43225.1 - 0.0017 18.5 10.5 0.11 12.9 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger SAP PF02037.22 EDP43226.1 - 1.8e-05 24.0 0.1 3.6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-Di19 PF05605.7 EDP43226.1 - 0.0032 17.5 1.5 0.018 15.1 0.2 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 EDP43226.1 - 0.0037 16.8 0.1 0.18 11.4 0.0 2.6 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDP43226.1 - 0.011 15.3 0.1 0.33 10.6 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EDP43226.1 - 0.047 14.0 1.2 2.8 8.4 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF859 PF05895.7 EDP43226.1 - 0.099 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) MFS_1 PF07690.11 EDP43227.1 - 2e-19 69.5 14.7 2e-19 69.5 10.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ERG2_Sigma1R PF04622.7 EDP43228.1 - 1.2e-87 292.7 0.0 1.6e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Spc24 PF08286.6 EDP43229.1 - 2.4e-06 27.2 2.1 2.4e-06 27.2 1.5 1.0 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 Spc7 PF08317.6 EDP43229.1 - 0.03 12.9 0.8 0.033 12.8 0.5 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.1 EDP43229.1 - 0.14 12.5 1.4 0.15 12.5 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TMCO5 PF14992.1 EDP43229.1 - 0.17 11.0 2.0 0.15 11.1 1.4 1.0 1 0 0 1 1 1 0 TMCO5 family Sin3_corepress PF08295.7 EDP43229.1 - 0.21 11.3 1.5 0.25 11.1 1.1 1.1 1 0 0 1 1 1 0 Sin3 family co-repressor TMF_DNA_bd PF12329.3 EDP43229.1 - 0.25 11.1 1.9 0.29 10.9 1.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EDP43229.1 - 0.26 10.7 1.1 0.29 10.6 0.8 1.2 1 0 0 1 1 1 0 Septum formation initiator CAF1A PF12253.3 EDP43230.1 - 4e-18 65.3 8.8 4e-18 65.3 6.1 2.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Pacs-1 PF10254.4 EDP43230.1 - 0.099 11.2 4.2 0.85 8.1 0.0 2.2 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein AAA PF00004.24 EDP43231.1 - 1.5e-15 57.5 0.0 3.5e-15 56.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EDP43231.1 - 3.9e-13 49.3 0.0 1.9e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDP43231.1 - 9.6e-08 31.1 0.0 2.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EDP43231.1 - 1.1e-07 31.6 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EDP43231.1 - 6e-07 29.6 0.0 3.4e-05 23.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP43231.1 - 3.9e-06 26.5 0.0 1.7e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EDP43231.1 - 1.7e-05 24.7 0.0 4.9e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 EDP43231.1 - 1.9e-05 24.3 0.0 3.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP43231.1 - 2.2e-05 23.6 0.0 4.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDP43231.1 - 4e-05 23.6 0.0 0.00039 20.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EDP43231.1 - 0.00019 20.6 0.0 0.0032 16.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDP43231.1 - 0.0011 18.7 0.0 0.0053 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EDP43231.1 - 0.0011 18.5 0.0 0.0039 16.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDP43231.1 - 0.0023 17.4 0.4 0.41 10.0 0.0 2.3 1 1 1 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EDP43231.1 - 0.0033 17.0 0.1 0.007 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDP43231.1 - 0.006 16.0 0.0 0.31 10.4 0.0 2.5 2 1 1 3 3 3 1 AAA-like domain AAA_17 PF13207.1 EDP43231.1 - 0.0078 17.0 0.0 0.019 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EDP43231.1 - 0.0079 16.1 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EDP43231.1 - 0.0087 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 EDP43231.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDP43231.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EDP43231.1 - 0.025 14.0 0.1 0.33 10.4 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EDP43231.1 - 0.027 13.4 0.0 0.059 12.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EDP43231.1 - 0.049 12.8 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EDP43231.1 - 0.058 13.0 0.0 0.25 10.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDP43231.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EDP43231.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EDP43231.1 - 0.069 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EDP43231.1 - 0.13 11.0 0.0 8.1 5.1 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 EDP43231.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ribosomal_S6 PF01250.12 EDP43232.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein S6 AA_kinase PF00696.23 EDP43233.1 - 2.6e-36 125.3 0.2 3.4e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EDP43233.1 - 5.1e-14 51.7 2.4 1.1e-13 50.6 0.0 2.8 3 1 0 3 3 3 1 PUA domain CBS PF00571.23 EDP43233.1 - 0.016 15.0 0.1 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 CBS domain WD40 PF00400.27 EDP43234.1 - 1.2e-08 34.4 17.9 5.9e-07 29.1 0.0 7.6 10 0 0 10 10 10 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP43234.1 - 0.00043 20.4 0.6 0.052 13.8 0.0 4.0 3 0 0 3 3 3 1 PQQ-like domain DEAD PF00270.24 EDP43236.1 - 7.5e-36 123.1 0.3 1.2e-35 122.5 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDP43236.1 - 0.0022 18.1 0.2 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDP43236.1 - 0.0035 17.2 0.6 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDP43236.1 - 0.015 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain CTP_transf_2 PF01467.21 EDP43238.1 - 4.3e-30 104.8 0.0 5.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Laminin_G_3 PF13385.1 EDP43239.1 - 1.6e-15 57.6 1.4 1.6e-15 57.6 1.0 2.3 2 1 1 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 EDP43239.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Sialidase PF02973.11 EDP43239.1 - 0.091 11.7 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Sialidase, N-terminal domain DEAD PF00270.24 EDP43241.1 - 2.1e-37 128.2 0.0 5e-37 126.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43241.1 - 8.7e-18 63.9 0.1 2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43241.1 - 0.019 14.8 0.0 0.042 13.6 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ORC3_N PF07034.6 EDP43242.1 - 0.0021 17.0 0.1 0.34 9.8 0.0 3.9 5 0 0 5 5 5 1 Origin recognition complex (ORC) subunit 3 N-terminus DIL PF01843.14 EDP43242.1 - 0.037 13.9 0.2 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 DIL domain CDP-OH_P_transf PF01066.16 EDP43243.1 - 1.3e-19 70.3 3.7 1.3e-19 70.3 2.5 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mito_carr PF00153.22 EDP43244.1 - 1.3e-23 82.5 0.0 2.3e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein NPR2 PF06218.6 EDP43245.1 - 4e-95 319.0 0.6 2.9e-41 141.5 0.1 3.1 2 1 1 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.8 EDP43245.1 - 3.5e-10 38.9 0.2 1.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Prion_bPrPp PF11587.3 EDP43246.1 - 0.022 14.3 0.2 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Sec63 PF02889.11 EDP43247.1 - 1.4e-09 37.5 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EDP43247.1 - 8.8e-05 22.0 0.0 0.00027 20.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD PF00270.24 EDP43248.1 - 9.7e-31 106.5 0.3 5.2e-30 104.1 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDP43248.1 - 7.3e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDP43248.1 - 3.1e-06 26.9 0.0 7.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDP43248.1 - 0.00036 20.6 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain Sec63 PF02889.11 EDP43248.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain SNF2_N PF00176.18 EDP43248.1 - 0.015 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AhpC-TSA PF00578.16 EDP43249.1 - 0.0027 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDP43249.1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 2 0 0 2 2 2 0 Redoxin PTPLA PF04387.9 EDP43250.1 - 4.5e-44 149.7 4.3 6e-44 149.3 3.0 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_transf_22 PF03901.12 EDP43251.1 - 1.7e-31 109.7 23.9 2.1e-31 109.3 16.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SNF2_N PF00176.18 EDP43252.1 - 3.7e-69 232.8 0.0 5.2e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDP43252.1 - 2.7e-21 75.4 0.0 6.5e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 EDP43252.1 - 6.2e-08 32.3 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDP43252.1 - 4.1e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDP43252.1 - 2.8e-05 23.8 0.0 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EDP43252.1 - 9e-05 22.0 13.1 9e-05 22.0 9.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP43252.1 - 0.0055 16.6 15.3 0.0055 16.6 10.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP43252.1 - 1.5 8.5 21.6 0.052 13.2 10.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP43252.1 - 1.7 8.4 22.0 0.21 11.3 10.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain APC10 PF03256.11 EDP43254.1 - 1.8e-35 122.2 0.1 4.5e-34 117.7 0.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) LAMTOR PF15454.1 EDP43254.1 - 0.049 13.9 0.3 0.099 12.9 0.2 1.6 1 1 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2808 PF10989.3 EDP43254.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) NIF PF03031.13 EDP43255.1 - 4.2e-26 91.5 0.1 3.8e-25 88.3 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Neugrin PF06413.6 EDP43255.1 - 0.45 10.2 8.1 0.77 9.5 5.6 1.2 1 0 0 1 1 1 0 Neugrin PTCB-BRCT PF12738.2 EDP43256.1 - 2.7e-08 33.5 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDP43256.1 - 5.5e-06 26.4 0.0 9.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain COPI_C PF06957.6 EDP43256.1 - 0.85 8.0 13.4 1.3 7.4 9.3 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF4633 PF15464.1 EDP43256.1 - 2.7 7.8 5.8 3.2 7.6 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4633) WD40 PF00400.27 EDP43257.1 - 1.2e-19 69.3 6.9 0.00076 19.2 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat VID27 PF08553.5 EDP43257.1 - 0.085 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ribosomal_S5_C PF03719.10 EDP43258.1 - 0.011 14.9 6.5 4.8 6.5 0.2 4.2 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain CbiX PF01903.12 EDP43258.1 - 1.1 9.4 18.3 0.51 10.4 0.4 4.8 2 1 2 4 4 4 0 CbiX GalP_UDP_tr_C PF02744.12 EDP43259.1 - 7.3e-46 155.7 0.0 1.2e-45 155.0 0.0 1.4 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EDP43259.1 - 2.4e-18 66.8 0.1 4.4e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain dCMP_cyt_deam_1 PF00383.17 EDP43260.1 - 1e-23 82.9 1.6 1.6e-23 82.3 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region tRNA-synt_2b PF00587.20 EDP43261.1 - 4.5e-22 78.4 0.0 3.9e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 EDP43261.1 - 1.7e-10 40.7 0.0 4e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA JmjC PF02373.17 EDP43262.1 - 1.6e-39 134.7 0.2 3.1e-39 133.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EDP43262.1 - 7.3e-15 54.2 0.1 1.2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EDP43262.1 - 5.5e-12 45.6 2.5 5.5e-12 45.6 1.7 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EDP43262.1 - 1.1e-11 44.7 2.6 3.5e-11 43.0 1.8 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 EDP43262.1 - 0.0067 16.0 1.7 0.023 14.3 1.2 1.9 1 0 0 1 1 1 1 PHD-finger TPT PF03151.11 EDP43263.1 - 4.3e-23 81.6 13.4 4.3e-23 81.6 9.3 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDP43263.1 - 0.00056 18.9 24.8 0.001 18.0 17.2 1.4 1 1 0 1 1 1 1 UAA transporter family Oxidored_q1_N PF00662.15 EDP43263.1 - 0.088 12.3 1.5 0.24 10.9 1.0 1.8 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Sec61_beta PF03911.11 EDP43263.1 - 1.7 8.4 5.2 21 5.0 0.2 3.7 3 0 0 3 3 3 0 Sec61beta family zf-RING_2 PF13639.1 EDP43264.1 - 0.00029 20.6 6.2 0.00029 20.6 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 EDP43264.1 - 0.0006 19.4 1.5 0.0006 19.4 1.1 2.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EDP43264.1 - 0.026 14.2 0.7 0.026 14.2 0.5 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 EDP43264.1 - 0.059 13.4 2.7 0.14 12.2 1.9 1.7 1 0 0 1 1 1 0 C1-like domain Cytochrom_CIII PF02085.11 EDP43264.1 - 0.12 12.4 5.9 0.32 11.0 0.8 2.5 2 0 0 2 2 2 0 Class III cytochrome C family Rubredoxin PF00301.15 EDP43264.1 - 0.25 11.2 0.1 0.25 11.2 0.0 3.0 2 1 0 2 2 2 0 Rubredoxin PHD PF00628.24 EDP43264.1 - 8.5 6.1 14.4 0.079 12.6 3.6 2.3 2 1 0 2 2 2 0 PHD-finger Mito_carr PF00153.22 EDP43266.1 - 8.1e-17 60.7 0.1 9.7e-17 60.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 EDP43267.1 - 2.8e-23 81.4 1.0 5.5e-15 54.8 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Sulfate_transp PF00916.15 EDP43267.1 - 0.31 10.0 3.0 1.6 7.6 0.1 2.1 1 1 2 3 3 3 0 Sulfate transporter family Ras PF00071.17 EDP43268.1 - 4.5e-65 217.9 0.9 5.9e-65 217.5 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP43268.1 - 4.9e-21 75.4 0.0 4.9e-21 75.4 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EDP43268.1 - 7.3e-18 64.4 0.1 1e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDP43268.1 - 1.2e-06 27.8 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDP43268.1 - 7.3e-06 25.5 0.3 1.5e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDP43268.1 - 1.1e-05 24.7 0.1 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDP43268.1 - 5e-05 23.2 1.1 8.2e-05 22.5 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDP43268.1 - 0.00022 20.4 1.2 0.0017 17.5 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDP43268.1 - 0.00027 21.0 0.0 0.00027 21.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain FeoB_N PF02421.13 EDP43268.1 - 0.0027 17.0 0.1 0.02 14.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 EDP43268.1 - 0.0041 16.6 1.5 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EDP43268.1 - 0.0066 16.6 0.1 0.5 10.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP43268.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EDP43268.1 - 0.018 15.3 1.6 0.35 11.1 1.1 2.4 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EDP43268.1 - 0.036 13.0 0.0 0.19 10.6 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 EDP43268.1 - 0.041 13.8 0.2 0.041 13.8 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 EDP43268.1 - 0.069 12.7 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EDP43268.1 - 0.072 12.5 0.1 1.1 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sec7 PF01369.15 EDP43269.1 - 1.6e-58 197.5 0.0 2.7e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EDP43269.1 - 8.5e-13 48.0 6.3 4.5e-12 45.7 3.7 2.5 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Med31 PF05669.7 EDP43270.1 - 2.5e-31 107.4 2.8 3.2e-31 107.1 1.9 1.1 1 0 0 1 1 1 1 SOH1 AAR2 PF05282.6 EDP43271.1 - 2.1e-54 184.8 0.0 2.6e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_L2_C PF03947.13 EDP43272.1 - 9.8e-42 141.8 1.4 1.4e-41 141.3 0.9 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDP43272.1 - 1.6e-13 50.3 0.1 3.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain EXS PF03124.9 EDP43273.1 - 7e-57 193.0 14.1 8.7e-57 192.6 9.8 1.0 1 0 0 1 1 1 1 EXS family SDA1 PF05285.7 EDP43274.1 - 4.4e-85 285.8 36.1 1.2e-83 281.1 23.4 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EDP43274.1 - 1.9e-19 69.7 0.7 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 NUC130/3NT domain DEAD PF00270.24 EDP43275.1 - 2.6e-36 124.6 0.0 5.2e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDP43275.1 - 3.1e-19 68.2 0.1 6e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDP43275.1 - 8.1e-19 67.2 0.0 1.9e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43275.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDP43275.1 - 0.022 13.5 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain RRM_3 PF08777.6 EDP43276.1 - 0.0043 16.8 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif La PF05383.12 EDP43277.1 - 2.6e-21 75.1 0.0 5.4e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EDP43277.1 - 1.1e-09 38.1 0.1 3.1e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP43277.1 - 1e-07 31.4 0.7 2.3e-07 30.3 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43277.1 - 3.2e-05 23.6 0.4 9.1e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VTC PF09359.5 EDP43278.1 - 1.1e-102 342.8 0.1 2.1e-102 341.9 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EDP43278.1 - 8.8e-25 88.0 6.2 8.8e-25 88.0 4.3 2.5 2 0 0 2 2 2 1 SPX domain DUF202 PF02656.10 EDP43278.1 - 8.2e-12 45.1 3.8 8.2e-12 45.1 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 EDP43278.1 - 1 9.0 4.4 8.7 6.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) COX15-CtaA PF02628.10 EDP43279.1 - 9.7e-82 274.2 5.1 1.3e-81 273.7 3.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PepSY_TM_1 PF13172.1 EDP43279.1 - 0.72 9.6 0.0 0.72 9.6 0.0 4.0 4 0 0 4 4 4 0 PepSY-associated TM helix SH3_1 PF00018.23 EDP43280.1 - 2.1e-12 46.2 0.0 3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDP43280.1 - 5.5e-12 45.0 0.0 7.7e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDP43280.1 - 3.1e-07 29.7 0.0 5.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Dscam_C PF12355.3 EDP43280.1 - 0.078 13.2 0.7 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal HLH PF00010.21 EDP43281.1 - 1.6e-13 50.0 0.0 3.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.24 EDP43282.1 - 4.7e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP43282.1 - 0.0012 19.0 0.0 0.0075 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP43282.1 - 0.011 16.5 0.0 0.053 14.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EDP43282.1 - 0.026 13.4 0.1 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EDP43282.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.1 EDP43282.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 EDP43282.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EDP43282.1 - 0.12 12.3 4.6 0.099 12.6 0.4 2.8 2 2 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EDP43282.1 - 0.16 11.6 0.1 0.55 9.9 0.1 1.8 1 1 1 2 2 2 0 NTPase DSPn PF14671.1 EDP43284.1 - 5e-35 120.5 0.0 3.1e-34 117.9 0.0 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EDP43284.1 - 2.2e-14 53.1 0.0 8.8e-14 51.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDP43284.1 - 0.00024 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Mif2_N PF15624.1 EDP43284.1 - 5.7 7.5 5.6 2 9.0 1.7 1.8 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal EMG1 PF03587.9 EDP43285.1 - 2.3e-75 252.3 0.0 5e-75 251.2 0.0 1.5 2 0 0 2 2 2 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.2 EDP43286.1 - 7.6e-22 77.4 0.6 4.2e-10 39.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP43286.1 - 7.7e-20 70.8 2.0 3e-11 43.4 0.3 4.2 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EDP43286.1 - 3.4e-19 67.6 0.2 2.1e-07 30.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EDP43286.1 - 4.3e-17 60.5 0.6 0.00012 21.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EDP43286.1 - 5.6e-17 61.3 1.0 6.4e-07 29.4 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EDP43286.1 - 5.1e-06 26.0 0.1 2.3e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Vir_act_alpha_C PF10400.4 EDP43286.1 - 0.033 14.5 0.4 0.12 12.7 0.3 1.9 1 0 0 1 1 1 0 Virulence activator alpha C-term Clp1 PF06807.9 EDP43287.1 - 2.3e-08 34.0 0.0 1.4e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EDP43287.1 - 2.3e-06 27.3 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDP43287.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 EDP43288.1 - 1.3e-63 210.7 3.4 3.8e-21 74.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3411 PF11891.3 EDP43288.1 - 0.07 12.8 0.0 0.74 9.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3411) PMT PF02366.13 EDP43289.1 - 8.9e-80 267.5 15.7 1.6e-79 266.7 10.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDP43289.1 - 2.3e-28 99.0 0.0 5.7e-28 97.7 0.0 1.7 1 1 0 1 1 1 1 MIR domain 5-FTHF_cyc-lig PF01812.15 EDP43290.1 - 3.7e-30 105.0 0.0 4.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2572 PF10833.3 EDP43290.1 - 0.084 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF1104 PF06518.6 EDP43290.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) ACBP PF00887.14 EDP43292.1 - 2.8e-08 33.2 0.0 3.2e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Peroxin-3 PF04882.7 EDP43293.1 - 1.1e-95 320.8 0.0 2.2e-95 319.9 0.0 1.4 1 1 0 1 1 1 1 Peroxin-3 ABC_tran PF00005.22 EDP43294.1 - 1.6e-45 154.7 0.0 1.8e-25 89.8 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDP43294.1 - 3.3e-18 66.6 1.4 0.0052 16.7 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EDP43294.1 - 2.1e-10 40.2 0.0 0.00038 19.7 0.0 3.5 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EDP43294.1 - 3.7e-08 32.9 0.2 7.4e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EDP43294.1 - 9.2e-07 28.3 0.2 0.027 13.9 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EDP43294.1 - 2.7e-06 26.7 0.0 0.13 11.2 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EDP43294.1 - 1.6e-05 24.8 0.0 0.0082 16.0 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase HEAT_EZ PF13513.1 EDP43294.1 - 1.8e-05 25.1 2.7 0.14 12.7 0.2 4.9 4 0 0 4 4 3 1 HEAT-like repeat AAA_23 PF13476.1 EDP43294.1 - 2.9e-05 24.5 5.2 0.027 14.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 EDP43294.1 - 6.5e-05 22.8 0.2 0.091 12.5 0.0 3.1 3 0 0 3 3 2 1 Domain of unknown function DUF87 Miro PF08477.8 EDP43294.1 - 6.7e-05 23.3 0.1 0.054 13.9 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein HEAT_2 PF13646.1 EDP43294.1 - 0.00028 21.0 11.7 0.057 13.6 2.0 4.2 1 1 0 3 3 3 2 HEAT repeats AAA_17 PF13207.1 EDP43294.1 - 0.0004 21.1 0.0 0.11 13.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDP43294.1 - 0.00052 20.1 0.0 1.9 8.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EDP43294.1 - 0.00054 19.6 0.2 0.11 12.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EDP43294.1 - 0.001 17.9 0.2 0.063 12.0 0.1 2.5 2 0 0 2 2 2 1 ArgK protein DUF258 PF03193.11 EDP43294.1 - 0.0012 18.0 0.0 0.037 13.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDP43294.1 - 0.0014 18.4 0.0 0.35 10.8 0.0 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EDP43294.1 - 0.0025 17.5 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EDP43294.1 - 0.0027 17.6 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDP43294.1 - 0.0049 15.9 0.1 7.1 5.6 0.0 3.5 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 EDP43294.1 - 0.0052 16.7 2.8 0.29 11.1 0.0 3.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EDP43294.1 - 0.0061 15.9 0.0 3.7 6.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDP43294.1 - 0.013 14.9 2.7 2.2 7.6 0.1 3.4 4 0 0 4 4 4 0 AAA-like domain cobW PF02492.14 EDP43294.1 - 0.034 13.6 0.1 7.1 6.0 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EDP43294.1 - 0.036 14.0 1.9 5.6 6.9 0.2 3.5 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EDP43294.1 - 0.047 13.5 0.0 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 EDP43294.1 - 0.058 13.5 0.0 1.7 8.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.22 EDP43294.1 - 0.07 12.5 0.1 4 6.8 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Tudor-knot PF11717.3 EDP43294.1 - 0.076 12.7 0.1 0.23 11.1 0.1 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain WD40 PF00400.27 EDP43295.1 - 5.5e-08 32.3 2.2 0.0035 17.1 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EDP43295.1 - 0.013 14.5 0.0 1.8 7.5 0.0 2.9 2 1 0 2 2 2 0 CPSF A subunit region Sec63 PF02889.11 EDP43296.1 - 1.7e-20 73.4 0.0 2.4e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EDP43296.1 - 1e-16 60.4 0.2 2.6e-16 59.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain NOA36 PF06524.7 EDP43296.1 - 5 6.2 23.5 8.1 5.6 16.3 1.3 1 0 0 1 1 1 0 NOA36 protein Fumble PF03630.9 EDP43297.1 - 1.5e-109 365.9 0.0 5.7e-82 275.3 0.0 2.2 2 0 0 2 2 2 2 Fumble StbA PF06406.6 EDP43297.1 - 0.02 13.8 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 StbA protein UPF0184 PF03670.8 EDP43297.1 - 0.12 12.5 0.1 0.4 10.8 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Spt4 PF06093.8 EDP43298.1 - 1.8e-30 104.6 0.3 2e-30 104.4 0.2 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MIF4G_like PF09088.6 EDP43299.1 - 3e-58 196.4 0.0 5.8e-58 195.4 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EDP43299.1 - 1.6e-38 132.3 0.6 1e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 MIF4G like Eaf7 PF07904.8 EDP43300.1 - 0.0012 18.7 0.1 0.0027 17.6 0.1 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Glyco_transf_15 PF01793.11 EDP43301.1 - 6.4e-131 436.2 9.0 8.2e-131 435.8 6.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EDP43302.1 - 1.2e-103 346.5 8.3 1.4e-103 346.3 5.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RNA_pol_A_bac PF01000.21 EDP43303.1 - 5.1e-28 97.4 0.0 9.5e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDP43303.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LIM_bind PF01803.11 EDP43304.1 - 2.4e-15 56.3 0.2 1.3e-11 44.0 0.1 2.4 2 1 0 2 2 2 2 LIM-domain binding protein DUF2456 PF10445.4 EDP43305.1 - 7.8e-21 73.7 0.8 1.6e-20 72.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) URO-D PF01208.12 EDP43306.1 - 2.7e-107 358.6 0.0 3e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TIP49 PF06068.8 EDP43307.1 - 1.7e-178 593.4 0.1 2.1e-178 593.1 0.1 1.1 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDP43307.1 - 7.4e-10 38.2 0.5 5.2e-05 22.3 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EDP43307.1 - 5.9e-09 36.2 1.4 2.3e-05 24.5 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP43307.1 - 3.6e-06 27.1 0.5 0.026 14.6 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP43307.1 - 3.1e-05 24.0 0.3 0.092 12.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 EDP43307.1 - 8.9e-05 22.1 0.2 0.00073 19.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EDP43307.1 - 0.00019 21.1 0.1 0.082 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDP43307.1 - 0.00055 19.3 0.4 0.0014 18.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDP43307.1 - 0.0019 18.1 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDP43307.1 - 0.0025 17.2 0.2 0.0097 15.3 0.1 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDP43307.1 - 0.011 15.6 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDP43307.1 - 0.012 15.0 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DnaB_C PF03796.10 EDP43307.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EDP43307.1 - 0.016 14.3 0.1 1 8.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EDP43307.1 - 0.03 13.3 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EDP43307.1 - 0.042 12.9 0.3 0.097 11.7 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EDP43307.1 - 0.05 13.2 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 CENP-S PF15630.1 EDP43307.1 - 0.057 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S NACHT PF05729.7 EDP43307.1 - 0.12 12.0 0.1 0.33 10.6 0.1 1.8 1 0 0 1 1 1 0 NACHT domain IMPDH PF00478.20 EDP43308.1 - 1.8e-138 461.2 0.0 1.3e-123 412.3 0.0 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EDP43308.1 - 1.2e-14 53.8 0.1 5.9e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EDP43308.1 - 2.9e-12 46.1 0.3 1.2e-11 44.1 0.4 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EDP43308.1 - 2.6e-11 43.2 9.4 4.7e-09 35.8 4.8 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EDP43308.1 - 2.6e-08 33.4 1.8 8.1e-06 25.2 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 EDP43308.1 - 0.00065 18.8 2.7 0.0013 17.8 0.7 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 EDP43308.1 - 0.0014 17.6 0.1 0.0032 16.4 0.1 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase B12-binding PF02310.14 EDP43308.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain EAL PF00563.15 EDP43308.1 - 0.0076 15.7 0.1 0.59 9.5 0.0 2.2 2 0 0 2 2 2 1 EAL domain PcrB PF01884.12 EDP43308.1 - 0.012 14.8 1.2 0.47 9.6 0.0 3.1 3 0 0 3 3 3 0 PcrB family Aldolase PF01081.14 EDP43308.1 - 0.015 14.4 0.3 0.049 12.7 0.0 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase Glu_synthase PF01645.12 EDP43308.1 - 0.018 13.9 1.9 0.032 13.1 1.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase PK PF00224.16 EDP43308.1 - 0.018 13.6 0.0 0.041 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Dus PF01207.12 EDP43308.1 - 0.026 13.3 0.5 0.57 8.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.7 EDP43308.1 - 0.082 11.9 0.4 12 4.9 0.0 2.5 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.16 EDP43308.1 - 0.085 11.8 3.0 0.24 10.3 0.2 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase TAF4 PF05236.9 EDP43309.1 - 2.3e-27 95.9 4.6 2.3e-27 95.9 3.2 2.7 1 1 1 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Glyco_transf_15 PF01793.11 EDP43310.1 - 5.3e-123 410.1 16.2 1.4e-122 408.8 11.2 1.6 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PPR_2 PF13041.1 EDP43311.1 - 8.7e-38 128.0 0.2 4.9e-11 42.4 0.0 10.5 9 2 3 12 12 12 8 PPR repeat family PPR_3 PF13812.1 EDP43311.1 - 2.4e-33 111.5 14.4 0.00018 21.5 0.0 12.9 14 0 0 14 14 14 7 Pentatricopeptide repeat domain PPR PF01535.15 EDP43311.1 - 3.8e-26 89.1 6.9 0.0011 18.8 0.0 12.7 12 2 0 12 12 12 5 PPR repeat PPR_1 PF12854.2 EDP43311.1 - 9.6e-16 56.9 0.0 1.2e-05 24.6 0.0 7.8 10 1 0 10 10 10 3 PPR repeat ECSIT PF06239.6 EDP43311.1 - 0.0026 16.6 0.0 0.23 10.3 0.0 3.0 4 0 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway Cytochrome_cB PF11783.3 EDP43311.1 - 0.2 11.2 1.9 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c bacterial TPR_14 PF13428.1 EDP43311.1 - 0.49 11.1 16.6 3.6 8.4 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat RRM_1 PF00076.17 EDP43312.1 - 0.00064 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nucleo_P87 PF07267.6 EDP43312.1 - 0.016 13.9 0.3 0.018 13.7 0.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRM_6 PF14259.1 EDP43312.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EDP43312.1 - 0.098 11.1 3.9 0.12 10.8 2.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Kinesin PF00225.18 EDP43313.1 - 2.7e-88 295.8 0.1 3.7e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain AMP_N PF05195.11 EDP43314.1 - 3.2e-35 120.4 0.0 4.9e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 EDP43314.1 - 0.012 15.1 0.1 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 Peptidase_M24 PF00557.19 EDP43315.1 - 6.8e-31 107.4 0.0 8.6e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 S4 PF01479.20 EDP43316.1 - 8.7e-12 44.2 0.0 2.4e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 EDP43316.1 - 5e-11 42.8 1.7 8.2e-11 42.1 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF530 PF04409.7 EDP43316.1 - 0.035 12.1 0.1 0.046 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Fe_hyd_lg_C PF02906.9 EDP43317.1 - 2e-67 227.4 0.0 3.1e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Syntaxin PF00804.20 EDP43318.1 - 1.6e-05 25.0 5.2 2.3e-05 24.4 2.3 1.9 1 1 1 2 2 2 1 Syntaxin DUF2562 PF10814.3 EDP43318.1 - 0.033 14.1 0.9 0.055 13.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) MRC1 PF09444.5 EDP43318.1 - 0.06 13.6 2.2 0.086 13.1 1.5 1.3 1 0 0 1 1 1 0 MRC1-like domain AAA_13 PF13166.1 EDP43318.1 - 0.12 10.8 3.1 0.15 10.5 2.1 1.0 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 EDP43318.1 - 0.12 12.3 1.5 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EDP43318.1 - 0.32 10.7 6.7 0.46 10.2 4.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PEP-utilisers_N PF05524.8 EDP43318.1 - 0.96 9.2 6.3 1.6 8.5 2.8 2.3 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal DUF2638 PF10937.3 EDP43319.1 - 1.5e-12 48.5 0.3 2.1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) NDUF_B7 PF05676.8 EDP43320.1 - 7.5e-18 63.7 0.2 9.1e-18 63.4 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EDP43320.1 - 0.018 14.8 0.5 0.024 14.3 0.3 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like XRN_N PF03159.13 EDP43322.1 - 9.2e-98 326.3 3.2 1.1e-97 326.1 0.0 2.5 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EDP43322.1 - 0.00014 21.6 5.8 0.00028 20.6 4.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EDP43322.1 - 0.63 9.8 4.7 0.62 9.8 1.8 2.1 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.9 EDP43322.1 - 4.3 5.2 18.8 0.6 8.0 8.9 2.1 2 0 0 2 2 2 0 CDC45-like protein PMI_typeI PF01238.16 EDP43323.1 - 4.4e-14 52.2 0.0 5.3e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PMI_typeI PF01238.16 EDP43324.1 - 1.6e-73 247.8 0.0 1.8e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EDP43324.1 - 2.8e-07 29.9 0.0 0.00011 21.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EDP43324.1 - 1e-06 28.4 0.0 0.00018 21.2 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain TipAS PF07739.8 EDP43324.1 - 0.054 13.8 0.2 0.083 13.2 0.2 1.2 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain PPR_3 PF13812.1 EDP43325.1 - 0.00047 20.2 0.2 0.023 14.9 0.0 3.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDP43325.1 - 0.00066 19.5 0.0 0.0039 17.1 0.0 2.3 3 0 0 3 3 3 1 PPR repeat family Abhydrolase_3 PF07859.8 EDP43326.1 - 1.7e-28 99.6 0.0 2.2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDP43326.1 - 1.9e-06 27.2 0.1 0.00026 20.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDP43326.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP43326.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EDP43326.1 - 0.00061 19.1 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EDP43326.1 - 0.00094 18.9 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EDP43326.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EDP43326.1 - 0.0092 15.2 0.0 0.021 14.0 0.0 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.7 EDP43326.1 - 0.065 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EDP43327.1 - 4.9e-34 117.7 0.0 6.2e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP43327.1 - 2.3e-05 24.2 0.0 4.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP43327.1 - 7e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP43327.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EDP43327.1 - 0.086 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EDP43327.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Acetyltransf_1 PF00583.19 EDP43328.1 - 2.4e-18 65.9 0.1 4e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDP43328.1 - 3.3e-10 40.1 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDP43328.1 - 2.4e-09 36.7 0.1 3.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDP43328.1 - 8.5e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDP43328.1 - 2.1e-07 30.8 0.1 3.2e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDP43328.1 - 4.2e-07 29.9 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDP43328.1 - 1.7e-05 25.0 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDP43328.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase CwfJ_C_1 PF04677.10 EDP43330.1 - 1.6e-29 101.9 0.0 2.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Cnd1 PF12717.2 EDP43331.1 - 2.2e-59 200.2 2.9 2.4e-54 183.8 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EDP43331.1 - 8.1e-44 149.2 0.6 3.6e-43 147.1 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EDP43331.1 - 5.5e-07 29.7 8.0 0.1 12.8 0.0 6.1 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 EDP43331.1 - 3.7e-05 24.0 10.5 0.069 13.6 0.2 5.9 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EDP43331.1 - 0.00011 21.9 9.8 0.97 9.6 0.1 6.6 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 EDP43331.1 - 0.00037 18.9 1.9 0.0085 14.4 0.0 2.8 3 0 0 3 3 3 1 Adaptin N terminal region Arm PF00514.18 EDP43331.1 - 0.14 12.0 2.0 8.8 6.3 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Sec62 PF03839.11 EDP43332.1 - 3.9e-48 163.8 3.7 6.4e-48 163.1 2.5 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Claudin_2 PF13903.1 EDP43332.1 - 0.034 13.8 0.1 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MFS_2 PF13347.1 EDP43332.1 - 0.16 10.3 7.2 0.22 9.8 5.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Alg6_Alg8 PF03155.10 EDP43333.1 - 4e-114 382.0 28.4 1.1e-55 189.3 2.3 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Actin PF00022.14 EDP43334.1 - 1.1e-127 425.7 0.0 1.3e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Actin Pkinase PF00069.20 EDP43335.1 - 2.1e-58 197.4 0.0 6e-58 196.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43335.1 - 8.1e-27 93.9 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3027 PF11228.3 EDP43335.1 - 0.07 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) UCH PF00443.24 EDP43336.1 - 9.3e-55 185.6 0.1 1.2e-54 185.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP43336.1 - 7.5e-30 104.3 4.9 5.4e-29 101.5 3.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DPBB_1 PF03330.13 EDP43337.1 - 2.1e-07 30.8 0.1 4e-07 29.9 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDP43337.1 - 5e-06 26.1 0.1 7.4e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Barwin family TIM21 PF08294.6 EDP43338.1 - 7.4e-14 51.6 0.0 1.3e-11 44.3 0.0 2.6 2 1 0 2 2 2 2 TIM21 Ribosomal_L10 PF00466.15 EDP43339.1 - 2e-17 62.9 0.0 2.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleoplasmin PF03066.10 EDP43339.1 - 2.2 7.7 8.1 3.7 7.0 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin HEAT_2 PF13646.1 EDP43340.1 - 4.3e-30 103.8 3.2 5.3e-15 55.4 0.0 2.9 2 1 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 EDP43340.1 - 1.7e-12 46.5 0.3 0.0008 19.6 0.0 6.6 7 1 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EDP43340.1 - 3.6e-12 46.3 1.8 0.0085 16.5 0.2 5.2 4 1 1 5 5 5 4 HEAT-like repeat HEAT PF02985.17 EDP43340.1 - 3.8e-09 35.8 1.3 0.28 11.3 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.18 EDP43340.1 - 0.0067 16.2 0.2 23 4.9 0.0 3.8 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EDP43340.1 - 0.06 13.3 1.2 8.9 6.3 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion UPF0147 PF03685.8 EDP43340.1 - 0.078 12.8 1.5 0.78 9.6 0.0 3.3 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0147) Ligase_CoA PF00549.14 EDP43341.1 - 4.2e-22 78.3 0.0 5.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EDP43341.1 - 2.9e-07 30.1 0.0 4.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DUF605 PF04652.11 EDP43342.1 - 5.1e-36 124.8 0.4 5.5e-36 124.7 0.3 1.0 1 0 0 1 1 1 1 Vta1 like DUF3654 PF12376.3 EDP43342.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) DWNN PF08783.6 EDP43343.1 - 8.5e-33 112.1 0.0 1.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EDP43343.1 - 3.6e-07 29.5 3.5 1e-06 28.0 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EDP43343.1 - 1e-05 25.1 2.0 2e-05 24.2 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EDP43343.1 - 0.00026 20.9 14.3 0.00026 20.9 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 EDP43343.1 - 0.0019 17.8 0.2 0.0054 16.4 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.1 EDP43343.1 - 0.002 17.7 11.0 0.002 17.7 7.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP43343.1 - 0.016 14.8 14.8 0.031 13.9 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 EDP43343.1 - 0.6 9.9 8.4 0.87 9.4 0.2 2.7 3 0 0 3 3 2 0 Transposase zinc-ribbon domain zf-CCHC_5 PF14787.1 EDP43343.1 - 1.1 8.8 5.1 0.39 10.2 0.7 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C3HC4_4 PF15227.1 EDP43343.1 - 1.2 9.0 13.8 2.6 8.0 9.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EDP43343.1 - 2.3 8.0 7.8 0.31 10.8 2.7 1.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Gin PF10764.4 EDP43343.1 - 5.5 6.7 7.9 3.1 7.5 2.2 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Sec8_exocyst PF04048.9 EDP43345.1 - 1.2e-27 96.3 0.0 2.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EDP43345.1 - 1.1e-07 31.0 0.1 2.1e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EDP43345.1 - 1.9e-06 27.8 2.2 1.5e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S5 PF00333.15 EDP43346.1 - 5e-14 51.7 0.3 8.5e-14 51.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDP43346.1 - 1.5e-13 49.8 0.1 3.9e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RRM_1 PF00076.17 EDP43347.1 - 2.4e-31 107.1 0.0 8.2e-18 63.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43347.1 - 4.8e-24 84.1 0.0 8.3e-13 48.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43347.1 - 6.1e-07 29.2 0.0 0.00043 20.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDP43347.1 - 0.076 12.8 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Macoilin PF09726.4 EDP43348.1 - 1.6 6.8 7.7 2.4 6.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_16 PF10294.4 EDP43349.1 - 5.6e-18 65.0 0.0 7.2e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDP43349.1 - 0.0015 19.1 0.0 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDP43349.1 - 0.0018 17.4 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EDP43349.1 - 0.0039 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EDP43349.1 - 0.036 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Hap4_Hap_bind PF10297.4 EDP43350.1 - 1.1e-06 28.2 4.4 2.5e-06 27.1 3.0 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EDP43350.1 - 7.8e-06 25.7 14.3 2.6e-05 24.0 7.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDP43350.1 - 0.0083 15.9 14.0 0.074 12.8 2.0 2.3 2 0 0 2 2 2 2 Basic region leucine zipper DUF1488 PF07369.6 EDP43350.1 - 6.2 6.7 7.3 1.2 9.0 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) RibD_C PF01872.12 EDP43351.1 - 2.5e-30 105.6 0.0 2.8e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain CHCH PF06747.8 EDP43352.1 - 1e-05 25.3 6.8 0.023 14.6 1.3 3.0 2 2 1 3 3 3 3 CHCH domain Cmc1 PF08583.5 EDP43352.1 - 0.00038 20.1 10.6 0.84 9.4 1.1 3.8 1 1 1 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EDP43352.1 - 0.044 13.8 9.7 1.2 9.1 3.9 3.1 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 NPBW PF15180.1 EDP43352.1 - 0.11 12.1 0.3 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Neuropeptides B and W COX17 PF05051.8 EDP43352.1 - 0.29 11.1 7.5 0.25 11.3 0.5 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.6 EDP43352.1 - 0.49 10.5 5.7 8.7 6.5 0.7 2.7 1 1 2 3 3 3 0 GCK domain UCR_hinge PF02320.11 EDP43352.1 - 0.54 10.2 8.5 4.3 7.3 0.5 3.4 1 1 3 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein Colipase-like PF15083.1 EDP43352.1 - 2.3 8.2 8.0 2.8 7.9 0.8 2.1 1 1 1 2 2 2 0 Colipase-like UPF0203 PF05254.7 EDP43352.1 - 4.9 7.0 7.6 7 6.5 0.0 3.1 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0203) DUF1903 PF08991.5 EDP43352.1 - 5 7.3 11.2 1.7 8.8 2.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) TIM PF00121.13 EDP43353.1 - 2.4e-53 180.7 0.0 2.5e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Cyclin_N PF00134.18 EDP43354.1 - 2.1e-12 46.7 2.0 1.9e-11 43.6 0.6 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDP43354.1 - 0.026 14.4 2.0 0.42 10.5 0.2 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.14 EDP43354.1 - 0.12 12.1 0.5 0.85 9.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DRMBL PF07522.9 EDP43355.1 - 3.2e-26 91.5 0.0 5.9e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EDP43355.1 - 5.7e-09 35.7 0.3 1.3e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDP43355.1 - 0.016 14.8 0.2 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lyase_1 PF00206.15 EDP43356.1 - 1.9e-22 79.8 0.0 2.8e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EDP43356.1 - 4.1e-17 61.9 0.0 9.1e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus SelR PF01641.13 EDP43357.1 - 1.7e-53 179.5 0.1 2e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EDP43357.1 - 0.0032 17.1 0.2 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 EDP43357.1 - 0.038 14.0 0.7 0.18 11.8 0.5 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1595 PF12760.2 EDP43357.1 - 0.071 12.9 0.5 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Mss51 PF13824.1 EDP43357.1 - 0.073 12.9 1.7 3.6 7.5 0.1 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 EDP43357.1 - 0.11 12.3 3.0 0.56 10.0 2.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EDP43357.1 - 0.19 11.1 4.2 1.2 8.6 0.1 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit NOB1_Zn_bind PF08772.6 EDP43357.1 - 0.4 10.5 1.9 2.1 8.2 0.1 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF1604 PF07713.8 EDP43358.1 - 9.6e-06 25.3 0.9 9.6e-06 25.3 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EDP43358.1 - 1.1e-05 25.1 1.5 2.3e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 G-patch domain TP_methylase PF00590.15 EDP43359.1 - 0.00026 20.7 0.7 0.0008 19.1 0.1 2.1 1 1 1 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1900 PF08954.6 EDP43360.1 - 3e-43 146.5 0.0 1.5e-41 141.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EDP43360.1 - 2.7e-21 74.9 0.0 4.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EDP43360.1 - 3.7e-14 51.9 1.7 7.7e-05 22.4 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF904 PF06005.7 EDP43360.1 - 0.038 14.2 1.4 0.075 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EDP43360.1 - 5.7 7.3 5.4 0.54 10.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nop25 PF09805.4 EDP43361.1 - 5e-17 62.2 13.4 5e-17 62.2 9.3 2.7 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) CAF1A PF12253.3 EDP43361.1 - 0.64 10.1 5.2 30 4.8 0.0 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A MAT1 PF06391.8 EDP43362.1 - 1.1e-37 129.6 28.4 1.3e-37 129.3 19.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 EDP43362.1 - 1.2e-05 24.8 6.8 4e-05 23.1 4.8 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP43362.1 - 1.5e-05 24.5 5.2 3.7e-05 23.3 3.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP43362.1 - 1.9e-05 24.2 6.7 0.00015 21.4 5.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDP43362.1 - 9.7e-05 22.3 7.6 0.00048 20.0 5.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP43362.1 - 0.00073 19.3 7.6 0.0027 17.4 5.6 1.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 EDP43362.1 - 0.0063 16.0 4.4 0.048 13.2 1.0 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DZR PF12773.2 EDP43362.1 - 0.15 11.9 4.2 0.42 10.4 2.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.5 EDP43362.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.8 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) zf-RING_UBOX PF13445.1 EDP43362.1 - 2 8.2 4.9 5.5 6.7 3.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger YhfH PF14149.1 EDP43362.1 - 2.1 8.2 5.6 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 YhfH-like protein zf-C3HC4_4 PF15227.1 EDP43362.1 - 2.4 8.0 7.9 7.8 6.4 5.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4662 PF15578.1 EDP43362.1 - 4 6.9 9.1 6.7 6.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Zn-ribbon_8 PF09723.5 EDP43362.1 - 7.8 6.5 8.5 25 4.8 3.4 2.8 2 1 0 2 2 2 0 Zinc ribbon domain UbiA PF01040.13 EDP43363.1 - 1e-28 100.2 20.0 1.3e-28 99.8 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3176 PF11374.3 EDP43363.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) adh_short PF00106.20 EDP43364.1 - 3.5e-30 105.1 1.6 5.3e-30 104.5 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP43364.1 - 1.7e-13 50.6 0.6 2.8e-13 49.9 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDP43364.1 - 8e-13 48.7 0.1 9.1e-13 48.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDP43364.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DASH_Dam1 PF08653.5 EDP43366.1 - 2.8e-19 68.6 0.2 3.9e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Acylphosphatase PF00708.13 EDP43367.1 - 2.6e-15 56.2 0.0 2.6e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Acyltransferase PF01553.16 EDP43368.1 - 1.1e-13 50.7 0.0 9.4e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase UvrD_C PF13361.1 EDP43369.1 - 2.8e-74 250.6 0.0 6.8e-74 249.4 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EDP43369.1 - 1.1e-57 195.7 0.0 2.4e-57 194.6 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EDP43369.1 - 8.5e-13 47.8 0.9 1.7e-11 43.7 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EDP43369.1 - 2.3e-12 46.9 0.0 6.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EDP43369.1 - 5.8e-08 32.5 0.7 0.023 14.2 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EDP43369.1 - 0.00092 18.8 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDP43369.1 - 0.0026 17.3 0.1 0.0064 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDP43369.1 - 0.1 11.9 0.0 5.4 6.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EDP43370.1 - 1.8e-55 184.6 5.4 4.1e-19 68.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tropomyosin_1 PF12718.2 EDP43371.1 - 0.0024 17.7 8.6 0.0024 17.7 6.0 2.8 1 1 2 3 3 3 2 Tropomyosin like DUF3584 PF12128.3 EDP43371.1 - 2.1 5.5 39.0 3.9 4.6 27.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 EDP43371.1 - 4.9 6.3 36.6 5.1 6.2 14.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PAP2 PF01569.16 EDP43372.1 - 1.7e-11 43.9 4.0 2.9e-11 43.1 2.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.17 EDP43372.1 - 1.5e-08 34.2 0.4 2e-07 30.5 0.3 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EDP43372.1 - 9e-05 22.1 0.1 0.00015 21.4 0.1 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NnrU PF07298.6 EDP43372.1 - 0.0081 15.5 3.6 0.0081 15.5 2.5 1.7 2 0 0 2 2 2 1 NnrU protein DUF1634 PF07843.6 EDP43372.1 - 1 8.9 3.6 0.88 9.2 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1634) Rsm1 PF08600.5 EDP43373.1 - 0.14 12.0 2.1 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 Rsm1-like Peptidase_M20 PF01546.23 EDP43374.1 - 6.4e-30 104.0 0.0 1.6e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDP43374.1 - 1e-14 54.2 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EDP43374.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 TPK_catalytic PF04263.11 EDP43375.1 - 2e-20 72.5 0.3 1.4e-19 69.9 0.2 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPR_11 PF13414.1 EDP43376.1 - 2.1e-18 65.7 2.1 3.8e-08 32.8 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.1 EDP43376.1 - 3.5e-12 45.8 3.4 7e-05 23.1 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDP43376.1 - 4.1e-12 45.0 0.9 0.00032 20.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP43376.1 - 7e-12 44.4 2.9 1.8e-05 24.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43376.1 - 2.5e-10 39.6 2.3 0.0029 17.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43376.1 - 6.7e-10 39.3 0.8 0.0016 19.0 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43376.1 - 1.3e-08 35.0 2.0 7e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43376.1 - 2.8e-07 30.3 1.6 6.8e-06 25.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP43376.1 - 3.5e-07 29.5 5.2 0.012 15.3 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43376.1 - 1.6e-05 25.0 1.8 3.6 8.2 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDP43376.1 - 3.9e-05 23.6 5.1 0.0066 16.5 0.2 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP43376.1 - 0.0002 21.1 0.8 0.018 14.8 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP43376.1 - 0.0048 16.5 1.4 0.17 11.7 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 EDP43376.1 - 0.0085 14.8 0.4 0.022 13.5 0.3 1.6 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_5 PF12688.2 EDP43376.1 - 0.077 13.0 0.3 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Tetratrico peptide repeat RTC4 PF14474.1 EDP43377.1 - 1.9e-12 47.2 0.0 3.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Telomere_Sde2 PF13019.1 EDP43378.1 - 5.9e-33 113.8 0.4 1.4e-32 112.6 0.3 1.5 1 0 0 1 1 1 1 Telomere stability and silencing Pheromone PF08015.6 EDP43378.1 - 0.54 11.1 3.9 1.1 10.1 2.7 1.4 1 0 0 1 1 1 0 Fungal mating-type pheromone Amidase PF01425.16 EDP43379.1 - 5.4e-43 147.4 0.0 6.1e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Mito_carr PF00153.22 EDP43380.1 - 1.8e-56 187.8 8.5 2.2e-19 68.9 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Nop52 PF05997.7 EDP43381.1 - 1e-57 195.0 0.0 1.5e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 EDP43381.1 - 0.0079 15.4 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Dabb PF07876.7 EDP43382.1 - 1.2e-08 35.2 0.1 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PIG-S PF10510.4 EDP43384.1 - 3.3e-99 332.9 2.0 3.1e-86 290.1 0.1 2.0 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Pex24p PF06398.6 EDP43385.1 - 5.2e-27 94.5 8.4 1.4e-26 93.1 5.8 1.7 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DivIVA PF05103.8 EDP43385.1 - 0.9 9.5 4.9 1.3 9.0 3.4 1.2 1 0 0 1 1 1 0 DivIVA protein ATP12 PF07542.6 EDP43386.1 - 6.7e-38 129.3 0.0 1.4e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Erythro-docking PF09277.6 EDP43386.1 - 0.0028 17.3 0.0 0.011 15.3 0.0 2.0 1 0 0 1 1 1 1 Erythronolide synthase, docking M20_dimer PF07687.9 EDP43386.1 - 0.026 14.2 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase dimerisation domain Lyase_aromatic PF00221.14 EDP43386.1 - 0.065 11.6 0.9 0.11 10.9 0.6 1.4 1 0 0 1 1 1 0 Aromatic amino acid lyase TPR_11 PF13414.1 EDP43387.1 - 8.3e-12 44.5 3.5 1.4e-08 34.2 0.2 2.2 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDP43387.1 - 2.1e-07 30.2 2.4 0.0077 15.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP43387.1 - 2.8e-06 26.8 9.8 0.00057 19.5 0.3 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43387.1 - 0.00021 21.8 0.6 0.18 12.4 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43387.1 - 0.00095 19.5 0.4 0.026 15.1 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP43387.1 - 0.0014 18.2 0.5 0.36 10.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43387.1 - 0.0069 16.7 0.7 0.13 12.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43387.1 - 0.011 15.5 0.4 4.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP43387.1 - 0.019 14.7 0.3 0.89 9.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP43387.1 - 0.033 14.3 2.5 0.38 10.9 1.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDP43387.1 - 0.11 12.7 0.2 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43387.1 - 0.22 12.0 1.8 7.1 7.3 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDP43387.1 - 0.86 9.5 2.9 1.4 8.8 0.1 2.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EDP43387.1 - 1.5 8.7 7.5 2.2 8.2 0.2 2.9 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain NADH-u_ox-rdase PF10785.4 EDP43388.1 - 1.2e-33 115.1 0.1 1.9e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EDP43388.1 - 0.00028 20.5 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Oligomerisation PF02410.10 EDP43389.1 - 6.5e-10 38.9 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Oligomerisation domain Neugrin PF06413.6 EDP43389.1 - 4.1e-08 33.3 0.1 6e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EDP43389.1 - 1e-05 25.5 1.0 1.7e-05 24.8 0.7 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Clat_adaptor_s PF01217.15 EDP43390.1 - 1.2e-41 141.7 0.4 1.4e-41 141.5 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SYS1 PF09801.4 EDP43391.1 - 1.7e-22 79.9 8.9 1.5e-16 60.6 4.1 2.3 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Mannosyl_trans2 PF04188.8 EDP43392.1 - 5.3e-57 193.6 11.2 8.3e-57 193.0 7.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) SRP54 PF00448.17 EDP43393.1 - 7.5e-76 253.9 0.1 1.3e-75 253.2 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EDP43393.1 - 1.5e-23 83.0 0.9 1.5e-23 83.0 0.6 3.8 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EDP43393.1 - 5.7e-13 48.7 0.2 1.2e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EDP43393.1 - 1.3e-06 28.3 0.0 4.2e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDP43393.1 - 3.5e-05 23.5 0.0 7.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EDP43393.1 - 7.9e-05 22.1 0.1 0.00034 20.1 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EDP43393.1 - 9.4e-05 22.5 0.0 0.00047 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EDP43393.1 - 0.00015 20.6 0.2 0.013 14.3 0.0 3.0 2 1 0 2 2 2 1 ArgK protein CbiA PF01656.18 EDP43393.1 - 0.00038 19.9 0.0 0.0016 17.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.12 EDP43393.1 - 0.0085 15.4 0.8 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_10 PF12846.2 EDP43393.1 - 0.011 15.1 0.0 0.035 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain APS_kinase PF01583.15 EDP43393.1 - 0.012 15.2 0.0 0.035 13.7 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.1 EDP43393.1 - 0.014 15.3 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EDP43393.1 - 0.019 13.6 0.2 0.25 9.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EDP43393.1 - 0.03 14.6 0.1 0.23 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EDP43393.1 - 0.057 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDP43393.1 - 0.059 14.1 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 EDP43393.1 - 0.067 12.2 0.2 1.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Anion-transporting ATPase DUF2203 PF09969.4 EDP43393.1 - 0.18 12.0 1.8 1.9 8.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) AAA_25 PF13481.1 EDP43393.1 - 0.19 11.0 2.0 1.7 8.0 0.2 2.8 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 EDP43393.1 - 0.64 9.2 3.2 3.8 6.6 0.5 3.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit XPG_I PF00867.13 EDP43394.1 - 1.2e-06 28.4 0.3 3.9e-06 26.8 0.2 1.8 2 0 0 2 2 2 1 XPG I-region Ribosomal_L10 PF00466.15 EDP43395.1 - 1.6e-05 24.7 0.1 0.0019 18.0 0.2 2.4 2 1 0 2 2 2 2 Ribosomal protein L10 Hydrolase PF00702.21 EDP43397.1 - 4.5e-17 63.1 0.2 9.2e-10 39.2 0.1 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDP43397.1 - 2.3e-08 33.3 0.6 4.2e-08 32.4 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EDP43397.1 - 4.3e-05 23.7 0.0 0.086 12.9 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDP43397.1 - 0.0017 17.9 0.9 0.003 17.1 0.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EDP43398.1 - 1.9e-27 95.1 0.1 1.2e-13 51.0 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 EDP43398.1 - 1.1e-18 67.1 0.2 3e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase DUF3433 PF11915.3 EDP43398.1 - 0.054 13.6 3.2 0.17 12.0 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3433) MafB19-deam PF14437.1 EDP43398.1 - 0.081 12.5 1.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 MafB19-like deaminase Toxin-deaminase PF14424.1 EDP43398.1 - 0.12 12.3 0.7 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases DUF2997 PF11211.3 EDP43398.1 - 0.13 11.6 0.7 12 5.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) zinc_ribbon_6 PF14599.1 EDP43398.1 - 0.15 11.8 0.9 5.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Ribosomal_L12 PF00542.14 EDP43399.1 - 4.4e-19 68.2 9.7 2.2e-18 66.0 4.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EDP43399.1 - 0.00086 19.6 6.8 0.00086 19.6 4.7 3.4 3 1 0 3 3 3 1 60s Acidic ribosomal protein DUF2789 PF10982.3 EDP43399.1 - 0.036 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) PBP_dimer PF03717.10 EDP43399.1 - 0.036 14.1 0.1 0.042 13.9 0.1 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain DUF2765 PF10963.3 EDP43399.1 - 0.075 12.9 1.4 0.096 12.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2765) Dor1 PF04124.7 EDP43399.1 - 0.087 11.2 0.1 0.16 10.3 0.1 1.4 1 0 0 1 1 1 0 Dor1-like family DUF4349 PF14257.1 EDP43399.1 - 0.1 11.7 2.8 0.18 11.0 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) ERG4_ERG24 PF01222.12 EDP43400.1 - 1.2e-116 389.7 19.3 1.4e-116 389.6 13.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Syja_N PF02383.13 EDP43401.1 - 3.3e-87 292.2 0.0 4.9e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Proteasome PF00227.21 EDP43402.1 - 3.2e-53 179.8 0.2 4.1e-53 179.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit FTR1 PF03239.9 EDP43403.1 - 0.066 12.1 0.9 0.084 11.8 0.6 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Homoserine_dh PF00742.14 EDP43404.1 - 2.2e-47 161.0 0.0 4.1e-47 160.1 0.0 1.5 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EDP43404.1 - 1.2e-15 57.8 0.3 2.9e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EDP43404.1 - 0.011 16.0 0.2 0.049 13.9 0.1 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.17 EDP43405.1 - 1.4e-77 261.2 0.0 2.6e-77 260.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NUDIX PF00293.23 EDP43406.1 - 1.2e-12 47.6 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUP PF06516.6 EDP43407.1 - 3.9e-77 259.1 0.0 4.5e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) YpM PF09144.5 EDP43407.1 - 0.068 13.1 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Yersinia pseudotuberculosis mitogen K_oxygenase PF13434.1 EDP43408.1 - 2e-05 23.6 0.0 0.004 16.1 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDP43408.1 - 0.00012 22.1 0.3 0.4 10.7 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDP43408.1 - 0.00096 18.1 0.6 2.7 6.8 0.0 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDP43408.1 - 0.0086 15.8 1.4 0.48 10.1 0.1 3.3 2 2 0 2 2 2 1 FAD-NAD(P)-binding PHD PF00628.24 EDP43410.1 - 3.4e-08 33.0 7.3 5.4e-08 32.4 5.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EDP43410.1 - 0.002 18.2 1.1 0.0035 17.4 0.8 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RanBP PF00641.13 EDP43410.1 - 0.026 13.6 0.2 0.044 12.8 0.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others PHD_2 PF13831.1 EDP43410.1 - 0.25 10.6 2.7 0.53 9.6 1.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-C4pol PF14260.1 EDP43410.1 - 1.5 8.9 4.9 4.9 7.2 0.4 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PPR_3 PF13812.1 EDP43411.1 - 0.0017 18.5 0.0 3.2 8.2 0.0 3.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain NAD_binding_6 PF08030.7 EDP43412.1 - 3.6e-17 62.6 0.0 4.8e-10 39.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDP43412.1 - 1.7e-13 50.3 0.0 6.1e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDP43412.1 - 6.8e-13 48.8 14.2 6.8e-13 48.8 9.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EDP43412.1 - 0.053 14.0 0.0 0.24 11.9 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF1049 PF06305.6 EDP43412.1 - 9.4 5.7 7.4 6.3 6.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) zf-DHHC PF01529.15 EDP43413.1 - 3.1e-14 52.7 7.8 3.1e-14 52.7 5.4 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DEAD PF00270.24 EDP43415.1 - 9.2e-36 122.8 0.2 1.5e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43415.1 - 6e-23 80.5 0.1 9.9e-12 44.5 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43415.1 - 9.6e-05 22.2 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DHHA2 PF02833.9 EDP43416.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EDP43416.1 - 4.3e-08 32.9 0.1 6.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DHH family TPR_11 PF13414.1 EDP43417.1 - 7.5e-18 63.9 17.2 3.5e-11 42.5 0.2 4.0 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EDP43417.1 - 1.2e-17 62.3 6.2 0.0013 18.4 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EDP43417.1 - 1.8e-17 62.0 0.4 2e-05 23.9 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDP43417.1 - 7.9e-11 40.9 2.6 0.039 13.7 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43417.1 - 3.9e-10 40.1 15.9 1.9e-07 31.5 0.2 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43417.1 - 4.7e-10 39.2 11.3 0.0022 17.8 0.2 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43417.1 - 1.3e-08 34.6 12.8 0.013 16.0 0.0 6.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43417.1 - 1.4e-08 34.2 5.9 0.00017 21.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43417.1 - 1.3e-07 31.8 6.8 0.11 12.8 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP43417.1 - 9.1e-06 25.1 4.3 0.86 9.5 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDP43417.1 - 1.2e-05 25.3 9.7 0.0075 16.3 0.5 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDP43417.1 - 0.0022 17.8 3.1 15 5.6 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP43417.1 - 0.0034 17.4 4.5 0.32 11.1 0.2 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDP43417.1 - 0.0042 17.4 6.6 0.62 10.6 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat IncA PF04156.9 EDP43417.1 - 0.041 13.4 0.1 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 IncA protein Coatomer_E PF04733.9 EDP43417.1 - 0.046 12.9 3.7 3.6 6.6 0.4 2.8 2 1 0 2 2 2 0 Coatomer epsilon subunit TPR_9 PF13371.1 EDP43417.1 - 0.1 12.4 5.4 5.6 6.8 0.0 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EDP43418.1 - 1.1e-41 142.6 0.0 1.6e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BRF1 PF07741.8 EDP43418.1 - 0.54 10.5 3.3 0.27 11.4 0.3 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rtf2 PF04641.7 EDP43419.1 - 0.00011 21.4 0.0 0.00024 20.3 0.0 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger Vps39_2 PF10367.4 EDP43420.1 - 4.1e-08 33.3 0.1 1.1e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EDP43420.1 - 9.3e-06 25.2 0.1 2e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 CNH domain PolyA_pol PF01743.15 EDP43421.1 - 3.9e-20 72.3 0.0 8.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EDP43421.1 - 3e-08 33.1 0.0 6.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.20 EDP43422.1 - 3.2e-65 219.8 0.0 4.1e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43422.1 - 5e-29 101.1 0.0 8.2e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43422.1 - 1.9e-06 27.0 0.0 5.2e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDP43422.1 - 0.024 14.3 2.3 0.09 12.4 0.5 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Synthase_beta PF11421.3 EDP43422.1 - 0.39 11.4 5.5 0.19 12.3 1.8 2.1 2 0 0 2 2 2 0 ATP synthase F1 beta subunit UAA PF08449.6 EDP43423.1 - 4.9e-63 212.8 20.7 2.7e-35 121.7 8.2 2.9 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.15 EDP43423.1 - 1.2e-08 35.0 22.1 2.2e-07 30.9 3.6 3.7 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EDP43423.1 - 9.8e-05 21.3 3.7 0.055 12.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EDP43423.1 - 0.015 15.4 24.1 0.037 14.2 3.7 3.6 3 2 0 3 3 3 0 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EDP43423.1 - 0.022 13.8 10.9 0.076 12.1 0.3 3.2 2 1 1 3 3 3 0 Nucleotide-sugar transporter TPT PF03151.11 EDP43423.1 - 0.11 12.1 21.6 0.05 13.2 7.5 3.4 3 1 0 3 3 3 0 Triose-phosphate Transporter family UPF0546 PF10639.4 EDP43423.1 - 0.68 9.7 11.2 1.9 8.3 1.2 3.1 2 1 0 3 3 3 0 Uncharacterised protein family UPF0546 DAP3 PF10236.4 EDP43424.1 - 4.5e-51 173.6 0.0 6.2e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EDP43424.1 - 7.1e-07 29.3 0.1 1.7e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDP43424.1 - 5.1e-05 22.7 0.3 0.00048 19.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDP43424.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EDP43424.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EDP43424.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EDP43424.1 - 0.017 15.2 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDP43424.1 - 0.018 14.7 0.0 0.073 12.8 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EDP43424.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 EDP43424.1 - 0.095 12.8 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDP43424.1 - 0.11 12.2 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SAGA-Tad1 PF12767.2 EDP43426.1 - 1.4 8.5 9.7 0.042 13.5 1.7 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GTP_EFTU PF00009.22 EDP43427.1 - 1.2e-47 161.7 0.0 2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDP43427.1 - 2.5e-19 68.9 0.0 4.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDP43427.1 - 3.1e-10 40.0 0.0 8.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP43427.1 - 0.0012 18.8 0.0 0.0028 17.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF866 PF05907.8 EDP43428.1 - 1.1e-29 103.0 0.5 1.3e-28 99.5 0.3 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 EDP43428.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c7 zf-DNA_Pol PF08996.5 EDP43428.1 - 0.062 12.6 1.3 0.4 10.0 0.0 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DUF164 PF02591.10 EDP43428.1 - 0.34 10.7 1.7 0.72 9.7 1.2 1.5 1 1 0 1 1 1 0 Putative zinc ribbon domain CDP-OH_P_transf PF01066.16 EDP43429.1 - 2e-10 40.8 5.2 2e-10 40.8 3.6 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase VHS PF00790.14 EDP43430.1 - 9.5e-06 25.3 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EDP43430.1 - 0.0066 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 GAT domain Metallophos PF00149.23 EDP43431.1 - 1.5e-43 148.5 0.3 1.9e-43 148.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD-oxidase_C PF02913.14 EDP43432.1 - 4.6e-50 170.2 0.0 6.2e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDP43432.1 - 3.1e-35 120.6 0.1 5.2e-35 119.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HIG_1_N PF04588.8 EDP43433.1 - 3.2e-05 23.5 0.9 6.7e-05 22.5 0.5 1.7 1 1 0 1 1 1 1 Hypoxia induced protein conserved region Nop53 PF07767.6 EDP43434.1 - 1.8e-71 241.2 22.8 2.1e-71 240.9 15.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Dermcidin PF15291.1 EDP43434.1 - 6 7.1 7.6 0.64 10.2 0.3 2.8 2 1 0 2 2 2 0 Dermcidin, antibiotic peptide OST3_OST6 PF04756.8 EDP43435.1 - 4.2e-18 65.4 4.2 6.3e-18 64.8 2.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family CcmH PF03918.9 EDP43435.1 - 0.15 11.0 0.5 0.79 8.6 0.0 2.3 2 1 0 2 2 2 0 Cytochrome C biogenesis protein DUF872 PF05915.7 EDP43435.1 - 0.2 11.5 2.5 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Ribosomal_L16 PF00252.13 EDP43436.1 - 1.2e-34 118.9 0.0 1.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pribosyltran PF00156.22 EDP43437.1 - 2.5e-14 53.0 0.0 5.2e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RnfC_N PF13375.1 EDP43437.1 - 0.0073 16.0 0.3 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PRTase_2 PF15609.1 EDP43437.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase WD40 PF00400.27 EDP43438.1 - 1.1e-57 189.9 26.4 3.3e-11 42.6 0.3 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat CLTH PF10607.4 EDP43438.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain VID27 PF08553.5 EDP43438.1 - 0.14 10.4 0.1 11 4.1 0.1 2.1 2 0 0 2 2 2 0 VID27 cytoplasmic protein HIT PF01230.18 EDP43439.1 - 6e-23 81.2 0.1 7.7e-23 80.8 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDP43439.1 - 3.6e-12 46.5 0.2 5.2e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDP43439.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Cid2 PF09774.4 EDP43440.1 - 1.8e-26 93.0 0.4 2.2e-26 92.7 0.3 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NAD_Gly3P_dh_C PF07479.9 EDP43441.1 - 4.3e-48 162.8 0.0 6.6e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EDP43441.1 - 2e-44 151.1 0.1 2.8e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EDP43441.1 - 9.2e-05 22.7 0.4 0.42 11.0 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent EI24 PF07264.6 EDP43443.1 - 1.4e-17 63.8 6.2 1.6e-17 63.6 4.3 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glyco_hydro_3 PF00933.16 EDP43444.1 - 4.7e-82 275.3 0.1 1.1e-81 274.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDP43444.1 - 9.2e-65 218.3 0.5 3.7e-64 216.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDP43444.1 - 3.6e-18 65.2 0.0 7.3e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.23 EDP43446.1 - 5.5e-14 51.9 0.0 9.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-U1 PF06220.7 EDP43447.1 - 3.4e-18 64.9 7.0 4.5e-18 64.5 4.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EDP43447.1 - 0.58 10.3 4.0 0.92 9.7 2.8 1.4 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 EDP43448.1 - 8e-43 145.8 0.0 1.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43448.1 - 1.4e-22 79.3 0.0 3.6e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43448.1 - 0.00034 20.4 0.0 0.00097 19.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF77 PF01910.12 EDP43449.1 - 2.1e-20 72.1 0.1 2.5e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF77 Aminotran_3 PF00202.16 EDP43450.1 - 2.2e-79 266.7 0.0 3.1e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III His_Phos_2 PF00328.17 EDP43451.1 - 5.1e-41 141.1 0.0 7.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GATase_2 PF00310.16 EDP43452.1 - 5.6e-18 64.7 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDP43452.1 - 2.1e-15 56.8 0.0 5.7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDP43452.1 - 5.3e-13 48.8 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EDP43452.1 - 6.1e-13 48.5 0.1 1.2e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EDP43452.1 - 5e-05 22.1 0.0 8.9e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Mito_carr PF00153.22 EDP43453.1 - 9.6e-67 220.7 3.5 8.2e-21 73.5 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Y_phosphatase2 PF03162.8 EDP43454.1 - 7.1e-22 77.5 0.0 7.3e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EDP43455.1 - 2.2e-14 53.1 0.0 2.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family SulA PF03846.9 EDP43455.1 - 0.091 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Cell division inhibitor SulA Aldo_ket_red PF00248.16 EDP43456.1 - 5.2e-27 94.4 0.0 6.6e-26 90.7 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Chitin_synth_2 PF03142.10 EDP43457.1 - 0.0054 15.1 0.6 0.007 14.7 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Ipi1_N PF12333.3 EDP43458.1 - 0.0077 16.1 1.2 0.059 13.3 0.0 3.1 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation DHDPS PF00701.17 EDP43458.1 - 0.046 12.3 0.0 0.14 10.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family FlgN PF05130.7 EDP43458.1 - 0.13 12.4 6.0 0.21 11.8 0.1 2.6 2 0 0 2 2 2 0 FlgN protein Ribosomal_S9 PF00380.14 EDP43459.1 - 7.8e-20 71.3 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 GP46 PF07409.7 EDP43459.1 - 0.13 11.6 0.1 7.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Phage protein GP46 Ribosomal_S11 PF00411.14 EDP43460.1 - 2.1e-15 56.8 0.1 3.1e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 BMF PF15185.1 EDP43460.1 - 0.45 9.7 2.7 0.35 10.1 1.0 1.4 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Hat1_N PF10394.4 EDP43461.1 - 9.2e-35 120.0 0.0 1.5e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 EDP43461.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDP43461.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDP43461.1 - 0.093 12.9 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TIP41 PF04176.8 EDP43462.1 - 1.5e-11 43.8 1.0 3.8e-07 29.5 0.8 2.0 1 1 1 2 2 2 2 TIP41-like family DLH PF01738.13 EDP43463.1 - 2.2e-11 43.4 0.0 2.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDP43463.1 - 5.7e-05 22.9 0.0 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP43463.1 - 0.02 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cation_efflux PF01545.16 EDP43464.1 - 4.6e-63 212.9 9.7 4.6e-63 212.9 6.7 3.2 2 1 1 3 3 3 1 Cation efflux family RasGEF PF00617.14 EDP43465.1 - 1.5e-55 187.8 0.1 3.4e-55 186.6 0.0 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDP43465.1 - 1.2e-21 76.8 0.1 3.1e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif WD40 PF00400.27 EDP43466.1 - 1.6e-17 62.6 8.6 4.5e-06 26.3 0.1 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat MCM PF00493.18 EDP43467.1 - 3.1e-140 466.6 0.2 3.8e-140 466.3 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EDP43467.1 - 6.2e-07 28.7 0.0 0.00014 21.1 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDP43467.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDP43467.1 - 0.00067 19.2 0.0 0.005 16.4 0.0 2.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP43467.1 - 0.081 12.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EDP43467.1 - 0.098 13.0 2.2 0.18 12.1 0.8 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Band_7 PF01145.20 EDP43468.1 - 4.5e-19 69.0 0.4 4.5e-19 69.0 0.3 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family GRP PF07172.6 EDP43468.1 - 0.013 15.9 8.5 0.022 15.2 5.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family RA PF00788.18 EDP43469.1 - 2.3e-14 53.6 0.2 1.7e-11 44.4 0.0 3.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EDP43469.1 - 1.7e-07 30.5 0.0 3.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDP43469.1 - 0.00037 20.0 0.0 0.00076 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TUG-UBL1 PF11470.3 EDP43469.1 - 0.14 12.1 0.1 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Chitin_synth_2 PF03142.10 EDP43470.1 - 6.2e-88 295.4 1.2 7.4e-88 295.2 0.8 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDP43470.1 - 0.0039 16.9 8.8 0.018 14.7 6.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EDP43471.1 - 3.9e-149 497.4 0.0 5.8e-149 496.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDP43471.1 - 2.4e-08 33.9 0.1 4.4e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDP43471.1 - 2.7e-08 33.8 0.0 5.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDP43471.1 - 3.2e-05 23.3 0.0 5.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDP43471.1 - 0.0047 16.6 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 RRM_1 PF00076.17 EDP43472.1 - 2.1e-16 59.3 0.0 2.4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43472.1 - 1.6e-13 50.3 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43472.1 - 2.4e-09 36.8 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FIST PF08495.5 EDP43473.1 - 4.2e-09 35.8 0.0 7.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 FIST N domain MoaC PF01967.16 EDP43474.1 - 2.5e-06 27.2 0.4 0.023 14.3 0.0 2.2 2 0 0 2 2 2 2 MoaC family PrpF PF04303.8 EDP43475.1 - 7e-53 179.6 0.1 1.5e-37 129.2 0.0 2.6 2 1 0 2 2 2 2 PrpF protein Epimerase PF01370.16 EDP43476.1 - 1.8e-41 142.1 0.0 2.2e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EDP43476.1 - 5.5e-27 93.4 0.0 9.9e-27 92.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EDP43476.1 - 3.9e-11 42.3 0.0 5.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EDP43476.1 - 1.3e-10 40.6 0.0 4.1e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EDP43476.1 - 2.3e-10 39.6 0.0 4.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDP43476.1 - 1.4e-08 33.9 0.0 8.2e-08 31.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EDP43476.1 - 3.1e-05 23.7 0.0 8.3e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EDP43476.1 - 5.1e-05 23.2 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDP43476.1 - 0.018 15.0 0.0 0.15 12.0 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding RPA_interact_C PF14768.1 EDP43478.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Meleagrin PF08189.6 EDP43478.1 - 1.2 8.6 4.0 0.27 10.7 0.3 1.9 2 0 0 2 2 2 0 Meleagrin/Cygnin family Ribosomal_L11_N PF03946.9 EDP43479.1 - 6.9e-15 54.2 0.1 1.2e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDP43479.1 - 2.1e-11 43.7 0.1 3.2e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.27 EDP43480.1 - 1.5e-54 180.0 17.1 3.7e-13 48.7 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EDP43480.1 - 1.9e-05 22.9 1.8 0.0084 14.2 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EDP43480.1 - 0.0023 16.2 0.0 0.19 10.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EDP43480.1 - 0.0049 16.4 0.1 30 4.4 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat RRM_1 PF00076.17 EDP43481.1 - 4.8e-22 77.3 0.0 6.4e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43481.1 - 8.9e-20 70.4 0.0 1.2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43481.1 - 2e-11 43.5 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxal_oxid_N PF07250.6 EDP43482.1 - 3.1e-27 95.2 0.0 4.6e-24 84.8 0.0 3.4 2 2 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EDP43482.1 - 3e-20 72.1 0.2 1e-19 70.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) VSP PF03302.8 EDP43482.1 - 0.15 10.6 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Ctr PF04145.10 EDP43482.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Kelch_4 PF13418.1 EDP43482.1 - 0.76 9.5 10.9 0.55 10.0 0.2 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Podoplanin PF05808.6 EDP43482.1 - 1.9 8.0 4.0 1.1 8.7 0.9 2.0 1 1 1 2 2 2 0 Podoplanin Mito_carr PF00153.22 EDP43483.1 - 7.2e-65 214.7 2.6 8.9e-24 83.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec23_trunk PF04811.10 EDP43484.1 - 3.4e-55 187.0 0.0 6.2e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDP43484.1 - 4.7e-26 90.2 0.1 7.9e-26 89.4 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDP43484.1 - 3.8e-19 69.0 0.0 8.2e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDP43484.1 - 5.6e-14 51.4 8.9 1.2e-13 50.3 6.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDP43484.1 - 7.6e-05 22.3 0.0 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Thymidylat_synt PF00303.14 EDP43485.1 - 4e-106 353.9 0.0 5.1e-106 353.6 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 EDP43485.1 - 1.3e-24 87.1 0.2 5.8e-24 84.9 0.0 2.2 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) zf-MYND PF01753.13 EDP43487.1 - 2.8e-07 30.2 14.9 5.6e-07 29.3 10.4 1.5 1 0 0 1 1 1 1 MYND finger Mur_ligase_M PF08245.7 EDP43488.1 - 7.3e-06 26.1 0.0 5e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain DUF429 PF04250.8 EDP43488.1 - 0.004 16.4 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF429) ATP_synt_H PF05493.8 EDP43489.1 - 1.3e-21 76.4 5.5 1.5e-21 76.2 3.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit H CD20 PF04103.10 EDP43489.1 - 0.0028 17.5 1.2 0.0029 17.5 0.9 1.0 1 0 0 1 1 1 1 CD20-like family DUF3311 PF11755.3 EDP43489.1 - 0.045 13.2 2.9 0.23 10.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) DUF4131 PF13567.1 EDP43489.1 - 0.069 12.5 1.5 0.072 12.5 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4117 PF13491.1 EDP43489.1 - 0.17 11.3 1.4 0.17 11.3 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) RPA_C PF08784.6 EDP43490.1 - 6.1e-15 55.4 0.2 1.4e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EDP43490.1 - 3.4e-08 33.2 0.0 5.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_36 PF13730.1 EDP43490.1 - 0.15 12.1 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PLU-1 PF08429.6 EDP43491.1 - 1.1e-45 156.0 0.3 2.1e-45 155.1 0.2 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 EDP43491.1 - 4.9e-41 139.5 0.3 1.4e-40 138.1 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EDP43491.1 - 1.4e-19 69.5 54.7 3.3e-09 36.2 4.4 4.1 4 0 0 4 4 4 3 PHD-finger JmjN PF02375.12 EDP43491.1 - 2.9e-15 55.4 0.1 6.1e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 jmjN domain ARID PF01388.16 EDP43491.1 - 2.6e-09 36.7 0.0 5.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EDP43491.1 - 1.7e-08 34.4 3.6 1.7e-08 34.4 2.5 3.6 4 0 0 4 4 4 1 C5HC2 zinc finger C1_1 PF00130.17 EDP43491.1 - 0.0055 16.4 5.0 0.0055 16.4 3.5 5.1 4 1 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_4 PF13717.1 EDP43491.1 - 0.095 12.4 0.1 0.095 12.4 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain ADK_lid PF05191.9 EDP43491.1 - 4.1 7.1 9.4 3.7 7.3 0.9 3.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.1 EDP43491.1 - 5 6.9 45.5 0.15 11.7 5.4 4.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 AAA PF00004.24 EDP43492.1 - 1.3e-40 138.6 0.0 2.1e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP43492.1 - 9.2e-07 29.0 0.2 0.00018 21.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDP43492.1 - 2.7e-05 24.1 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDP43492.1 - 8.5e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EDP43492.1 - 0.00026 20.7 0.5 0.0019 17.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDP43492.1 - 0.00031 20.7 0.2 0.0029 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EDP43492.1 - 0.00049 20.1 0.5 0.065 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDP43492.1 - 0.0023 17.0 0.0 0.0042 16.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDP43492.1 - 0.0038 17.1 0.0 0.0094 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EDP43492.1 - 0.0071 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDP43492.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP43492.1 - 0.0078 17.0 0.8 0.019 15.7 0.2 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EDP43492.1 - 0.0079 15.9 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EDP43492.1 - 0.011 16.0 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EDP43492.1 - 0.011 15.0 0.6 1.1 8.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDP43492.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EDP43492.1 - 0.018 14.1 0.1 0.25 10.4 0.0 2.3 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 EDP43492.1 - 0.025 13.4 0.0 0.077 11.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 EDP43492.1 - 0.055 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 EDP43492.1 - 0.085 11.5 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 EDP43492.1 - 0.093 11.6 0.1 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EDP43492.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EDP43492.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDP43492.1 - 0.14 11.7 0.2 0.52 9.9 0.1 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EDP43492.1 - 0.15 11.3 0.1 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Tim17 PF02466.14 EDP43493.1 - 5.4e-29 100.8 9.1 2.9e-27 95.2 6.3 2.2 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Abhydrolase_2 PF02230.11 EDP43493.1 - 0.039 13.4 0.4 9.8 5.5 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase E1-E2_ATPase PF00122.15 EDP43494.1 - 2e-63 213.5 1.0 2e-63 213.5 0.7 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EDP43494.1 - 3e-23 83.3 1.8 3.5e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP43494.1 - 2.7e-12 47.2 0.0 4.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDP43494.1 - 3.4e-07 29.6 0.0 7.5e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDP43494.1 - 0.0011 18.6 0.1 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP43494.1 - 0.0029 17.5 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit YrvL PF14184.1 EDP43494.1 - 8.9 6.1 13.1 0.15 11.8 3.4 2.2 2 0 0 2 2 2 0 Regulatory protein YrvL Cpn60_TCP1 PF00118.19 EDP43495.1 - 3.9e-156 520.4 1.6 4.5e-156 520.2 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.6 EDP43495.1 - 0.096 12.2 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Gly-zipper_OmpA PF13436.1 EDP43496.1 - 0.21 11.2 12.7 0.61 9.7 8.8 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SNF2_N PF00176.18 EDP43498.1 - 2.4e-67 226.8 0.0 3.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP43498.1 - 1e-11 44.4 0.0 2.4e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP43498.1 - 2.7e-08 33.8 0.0 6.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 EDP43498.1 - 5.2e-08 32.7 4.4 5.2e-08 32.7 3.1 2.9 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP43498.1 - 7.5e-08 31.9 4.9 7.5e-08 31.9 3.4 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP43498.1 - 1.6e-07 30.8 4.5 1.6e-07 30.8 3.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP43498.1 - 1.7e-06 27.7 5.9 1.7e-06 27.7 4.1 2.5 2 0 0 2 2 1 1 Ring finger domain DEAD PF00270.24 EDP43498.1 - 2.7e-06 27.0 0.0 6.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EDP43498.1 - 1.6e-05 24.5 5.6 1.6e-05 24.5 3.9 2.8 3 0 0 3 3 3 1 zinc-RING finger domain AAA_22 PF13401.1 EDP43498.1 - 0.0036 17.4 0.1 0.013 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain zf-RING_UBOX PF13445.1 EDP43498.1 - 0.0039 16.8 1.1 0.0039 16.8 0.7 2.1 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EDP43498.1 - 0.032 13.7 5.4 1.9 8.1 0.8 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 HEAT_2 PF13646.1 EDP43499.1 - 0.19 12.0 1.4 2.7 8.3 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats WD40 PF00400.27 EDP43501.1 - 2e-39 132.1 9.0 3.9e-09 36.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDP43501.1 - 3.8e-05 23.4 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EDP43501.1 - 0.063 12.7 0.0 0.95 9.0 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.24 EDP43502.1 - 3e-42 143.9 0.2 4.4e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43502.1 - 9.5e-24 83.0 0.1 2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EDP43502.1 - 0.0051 15.9 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Pam17 PF08566.5 EDP43503.1 - 2.1e-45 154.5 0.0 2.4e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DnaJ PF00226.26 EDP43504.1 - 2.4e-17 62.3 0.2 4.5e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain OmpH PF03938.9 EDP43504.1 - 1.2 9.0 9.7 1.8 8.4 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NMDAR2_C PF10565.4 EDP43504.1 - 5.4 5.5 7.8 6.5 5.3 4.7 1.5 1 1 1 2 2 2 0 N-methyl D-aspartate receptor 2B3 C-terminus SpecificRecomb PF10136.4 EDP43504.1 - 7.8 4.4 7.5 11 3.9 5.2 1.2 1 0 0 1 1 1 0 Site-specific recombinase RrnaAD PF00398.15 EDP43505.1 - 8.9e-23 80.6 0.0 1.9e-22 79.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase RHH_4 PF13467.1 EDP43506.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix domain APG17 PF04108.7 EDP43507.1 - 5.6e-05 22.1 6.7 0.043 12.6 0.1 2.5 3 0 0 3 3 3 2 Autophagy protein Apg17 Synaptonemal_3 PF15191.1 EDP43507.1 - 0.0058 16.3 0.5 0.15 11.7 0.0 3.0 2 1 0 2 2 2 1 Synaptonemal complex central element protein 3 Baculo_PEP_C PF04513.7 EDP43507.1 - 0.079 12.7 4.2 2.8 7.7 0.7 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3231 PF11553.3 EDP43507.1 - 0.15 11.5 1.3 1.4 8.4 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3231) Fip1 PF05182.8 EDP43508.1 - 7.3e-22 76.3 1.4 1.3e-21 75.6 1.0 1.4 1 0 0 1 1 1 1 Fip1 motif MPC PF03650.8 EDP43509.1 - 2.2e-23 82.4 0.2 2.5e-23 82.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) FAA_hydrolase PF01557.13 EDP43510.1 - 1.1e-55 188.4 0.0 1.4e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RNase_P_p30 PF01876.11 EDP43512.1 - 4.6e-35 120.0 0.1 7.7e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 HIT PF01230.18 EDP43513.1 - 0.055 14.0 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 HIT domain Aa_trans PF01490.13 EDP43514.1 - 8.5e-42 143.0 12.1 1e-41 142.7 8.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rad51 PF08423.6 EDP43515.1 - 7e-133 441.3 0.0 8.4e-133 441.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDP43515.1 - 1.6e-14 53.7 0.1 2.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDP43515.1 - 7.3e-09 35.1 0.1 9.4e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDP43515.1 - 3.4e-07 29.6 0.0 5.5e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EDP43515.1 - 0.036 12.9 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EDP43515.1 - 0.099 11.4 1.6 0.29 9.9 0.9 1.7 1 1 1 2 2 2 0 PAXNEB protein SNARE PF05739.14 EDP43516.1 - 2.6e-12 46.2 1.9 4.1e-12 45.5 0.4 2.1 2 0 0 2 2 2 1 SNARE domain Rad1 PF02144.11 EDP43517.1 - 2.3e-34 118.4 0.0 2.7e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 WD40 PF00400.27 EDP43518.1 - 6.7e-26 89.1 15.8 7.3e-10 38.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-H2C2_2 PF13465.1 EDP43519.1 - 3.3e-14 52.3 14.4 5.3e-07 29.6 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDP43519.1 - 5.5e-11 42.1 20.3 0.0001 22.4 2.9 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP43519.1 - 7.5e-08 32.1 14.8 0.0036 17.5 1.5 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDP43519.1 - 0.027 14.3 6.4 1.2 9.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDP43519.1 - 5 7.2 6.0 81 3.4 0.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Myosin_head PF00063.16 EDP43520.1 - 2.2e-60 204.5 0.0 2.8e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 EDP43520.1 - 0.04 13.9 0.2 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EDP43520.1 - 0.13 12.3 0.2 2.8 8.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Myosin_head PF00063.16 EDP43521.1 - 8.2e-11 40.6 0.0 8.5e-11 40.6 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF2730 PF10805.3 EDP43522.1 - 0.0077 15.9 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF2730 PF10805.3 EDP43524.1 - 0.0052 16.4 0.3 0.0096 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DUF1048 PF06304.6 EDP43524.1 - 0.11 12.7 0.6 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) Striatin PF08232.7 EDP43524.1 - 0.83 9.9 5.7 0.1 12.9 0.9 1.8 2 1 0 2 2 2 0 Striatin family MFS_1 PF07690.11 EDP43525.1 - 2e-11 43.2 32.5 2e-11 43.2 22.5 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily Gemini_mov PF01708.11 EDP43525.1 - 0.78 9.3 0.0 0.78 9.3 0.0 2.7 3 0 0 3 3 3 0 Geminivirus putative movement protein Ipi1_N PF12333.3 EDP43526.1 - 1.8e-10 40.6 3.3 1.8e-10 40.6 2.3 4.2 4 1 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation NUDIX PF00293.23 EDP43527.1 - 6.7e-16 58.1 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EDP43527.1 - 0.00012 22.3 0.0 0.00037 20.7 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EDP43527.1 - 0.00076 18.9 0.5 0.0013 18.1 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EDP43527.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EDP43527.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit GFA PF04828.9 EDP43527.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S19 PF00203.16 EDP43528.1 - 1.4e-24 85.4 0.0 1.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AAA_18 PF13238.1 EDP43529.1 - 7.7e-07 29.4 0.0 1.6e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP43529.1 - 3.3e-06 27.9 0.0 1.3e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EDP43529.1 - 2.2e-05 24.1 0.1 0.00022 20.8 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArdA PF07275.6 EDP43529.1 - 0.0035 17.6 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 Antirestriction protein (ArdA) ABC_tran PF00005.22 EDP43529.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EDP43529.1 - 0.021 14.7 0.0 0.05 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EDP43529.1 - 0.047 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EDP43529.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EDP43529.1 - 0.076 13.3 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDP43529.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SSrecog PF03531.9 EDP43530.1 - 2.7e-71 239.4 0.6 8.5e-49 165.8 0.0 3.2 2 1 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EDP43530.1 - 1.6e-27 95.2 0.1 3.4e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 Histone chaperone Rttp106-like CDC45 PF02724.9 EDP43530.1 - 0.00039 18.5 15.0 0.0034 15.5 1.0 2.1 2 0 0 2 2 2 2 CDC45-like protein Spore_coat_CotO PF14153.1 EDP43530.1 - 0.015 14.7 0.6 0.015 14.7 0.4 2.3 2 0 0 2 2 2 0 Spore coat protein CotO SDA1 PF05285.7 EDP43530.1 - 4.9 6.3 38.1 0.056 12.7 8.4 2.2 2 0 0 2 2 2 0 SDA1 zf-C3HC4_3 PF13920.1 EDP43531.1 - 1.3e-07 31.1 14.7 2.8e-07 30.0 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.13 EDP43532.1 - 1.3e-12 47.1 0.1 1.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EDP43532.1 - 0.092 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EDP43532.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 zinc-finger NRDE PF05742.7 EDP43533.1 - 7.2e-48 163.2 0.0 1.6e-47 162.1 0.0 1.5 1 1 0 1 1 1 1 NRDE protein Arrestin_C PF02752.17 EDP43535.1 - 2e-06 27.9 0.7 4.5e-06 26.8 0.3 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Ribonuc_red_lgC PF02867.10 EDP43536.1 - 6.1e-216 718.1 0.0 8.3e-216 717.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDP43536.1 - 4e-24 84.2 0.1 9.4e-24 83.0 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDP43536.1 - 2.1e-08 34.4 0.1 6.6e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EDP43536.1 - 0.02 12.9 0.0 0.031 12.3 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MARVEL PF01284.18 EDP43537.1 - 2.1e-13 50.2 15.2 2.9e-13 49.8 10.4 1.3 1 1 0 1 1 1 1 Membrane-associating domain Yip1 PF04893.12 EDP43537.1 - 0.17 11.4 17.8 0.34 10.3 12.0 1.6 1 1 0 1 1 1 0 Yip1 domain ABC2_membrane_4 PF12730.2 EDP43537.1 - 0.43 9.6 14.7 1.2 8.2 10.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4064 PF13273.1 EDP43537.1 - 9.2 6.4 11.4 3.3 7.8 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Brix PF04427.13 EDP43538.1 - 1.2e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain Brix PF04427.13 EDP43539.1 - 8.5e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain SPATA24 PF15175.1 EDP43539.1 - 0.031 13.9 0.7 0.04 13.5 0.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 WD40 PF00400.27 EDP43540.1 - 7e-27 92.3 6.0 5.9e-07 29.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Methyltransf_16 PF10294.4 EDP43541.1 - 3e-12 46.3 0.0 3.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EDP43541.1 - 0.001 18.2 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EDP43541.1 - 0.0027 17.1 0.0 0.0035 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EDP43541.1 - 0.0053 17.3 0.0 0.0074 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EDP43541.1 - 0.036 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PTCB-BRCT PF12738.2 EDP43542.1 - 1.8e-29 101.3 0.2 9.9e-12 44.5 0.0 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EDP43542.1 - 7.3e-24 83.7 0.0 2.4e-09 37.2 0.0 5.0 5 2 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain UDPGT PF00201.13 EDP43543.1 - 2e-05 23.3 0.0 2.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF1987 PF09345.5 EDP43543.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) YL1_C PF08265.6 EDP43544.1 - 6.1e-15 54.4 0.1 9.8e-15 53.8 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain YL1 PF05764.8 EDP43544.1 - 5.7e-11 42.4 1.5 5.7e-11 42.4 1.1 1.9 2 0 0 2 2 2 1 YL1 nuclear protein zf-HIT PF04438.11 EDP43544.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger Ribonuc_red_sm PF00268.16 EDP43545.1 - 2e-117 391.2 0.4 2.4e-117 390.9 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ndc80_HEC PF03801.8 EDP43546.1 - 2.5e-33 114.8 0.0 6.9e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family TMF_TATA_bd PF12325.3 EDP43546.1 - 0.0034 17.0 1.0 0.0034 17.0 0.7 4.7 3 1 1 4 4 4 1 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EDP43546.1 - 0.32 10.1 10.2 1.4 8.0 2.4 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EDP43546.1 - 0.43 10.8 5.9 3.9 7.8 0.1 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ExbD PF02472.11 EDP43546.1 - 0.44 10.5 2.2 0.52 10.3 0.0 2.2 3 0 0 3 3 3 0 Biopolymer transport protein ExbD/TolR WXG100 PF06013.7 EDP43546.1 - 1 9.3 12.8 7.2 6.6 0.1 4.8 3 2 0 4 4 4 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.7 EDP43546.1 - 1.2 8.8 33.1 0.55 9.9 1.1 4.0 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EDP43546.1 - 1.5 8.3 19.7 0.04 13.4 1.5 3.6 2 2 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 EDP43546.1 - 4.6 6.4 28.5 0.19 10.9 1.4 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.5 EDP43546.1 - 9.6 6.3 10.9 1.8 8.6 0.2 3.1 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family CAP_N PF01213.14 EDP43547.1 - 1.6e-93 313.4 0.1 2.3e-93 312.9 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EDP43547.1 - 3.1e-54 182.6 0.1 4.4e-54 182.1 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EDP43547.1 - 0.0037 16.6 0.4 0.0062 15.9 0.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 EDP43547.1 - 0.73 9.1 5.3 0.16 11.3 1.2 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator UCH PF00443.24 EDP43548.1 - 2.7e-47 161.1 0.0 3.6e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDP43548.1 - 2.1e-19 69.4 5.1 2.1e-19 69.4 3.6 4.1 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EDP43548.1 - 1.1e-17 64.4 0.0 4.2e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EDP43548.1 - 3.7e-13 48.8 0.1 1.9e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain RuvA_C PF07499.8 EDP43548.1 - 0.0032 17.5 0.1 0.26 11.5 0.0 2.6 2 0 0 2 2 2 1 RuvA, C-terminal domain UBA_4 PF14555.1 EDP43548.1 - 0.074 12.6 2.1 0.4 10.2 0.6 2.3 2 0 0 2 2 2 0 UBA-like domain TF_Zn_Ribbon PF08271.7 EDP43548.1 - 0.81 9.0 5.6 1.4 8.3 0.3 3.0 2 0 0 2 2 2 0 TFIIB zinc-binding Pex2_Pex12 PF04757.9 EDP43549.1 - 3.2e-48 164.1 5.4 5.4e-48 163.4 3.7 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 EDP43549.1 - 0.0066 16.1 3.6 0.011 15.4 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP43549.1 - 0.0088 16.0 4.3 0.015 15.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDP43549.1 - 0.41 10.5 5.9 0.72 9.7 4.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDP43549.1 - 0.42 10.4 7.5 1.5 8.7 5.2 1.8 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EDP43549.1 - 0.72 9.5 2.5 1.2 8.8 1.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thg1C PF14413.1 EDP43550.1 - 4.8e-45 152.1 0.0 6.9e-45 151.6 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EDP43550.1 - 1.1e-16 60.6 0.2 1.6e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase MSA-2c PF12238.3 EDP43551.1 - 0.0023 17.6 0.4 0.0044 16.7 0.3 1.4 1 0 0 1 1 1 1 Merozoite surface antigen 2c Pex14_N PF04695.8 EDP43551.1 - 0.49 10.4 3.8 0.41 10.6 1.3 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region STAG PF08514.6 EDP43553.1 - 3.1e-19 68.8 1.1 3.1e-19 68.8 0.7 2.0 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.2 EDP43553.1 - 0.0013 18.5 2.6 0.16 11.7 0.4 4.0 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 GCV_H PF01597.14 EDP43555.1 - 1.7e-31 108.4 0.3 2.1e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EDP43555.1 - 0.0018 17.8 0.2 0.0029 17.1 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EDP43555.1 - 0.0037 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 EDP43555.1 - 0.14 11.8 0.1 0.97 9.1 0.0 2.3 2 1 1 3 3 3 0 Biotin-lipoyl like Lipase_3 PF01764.20 EDP43556.1 - 3.1e-08 33.3 0.0 5.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDP43556.1 - 0.00018 21.3 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EDP43556.1 - 0.043 12.7 0.4 0.08 11.7 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) UPF0227 PF05728.7 EDP43556.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MutL_C PF08676.6 EDP43557.1 - 0.083 12.4 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 MutL C terminal dimerisation domain ComZ PF10815.3 EDP43557.1 - 0.16 11.7 0.5 5.1 6.9 0.0 2.5 3 0 0 3 3 3 0 ComZ WD40 PF00400.27 EDP43559.1 - 1.3e-43 145.3 20.0 1.4e-07 31.1 0.0 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat Es2 PF09751.4 EDP43560.1 - 2.1e-54 185.5 9.5 1.1e-52 179.9 6.6 2.3 1 1 0 1 1 1 1 Nuclear protein Es2 Rsm22 PF09243.5 EDP43561.1 - 8.2e-32 110.3 0.2 2.6e-21 75.8 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ima1_N PF09779.4 EDP43562.1 - 1.4e-20 74.1 1.7 1.6e-20 73.8 0.1 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain DUF2296 PF10058.4 EDP43562.1 - 0.066 12.9 1.3 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Cys_rich_KTR PF14205.1 EDP43562.1 - 0.1 12.0 1.4 8.5 5.9 0.0 3.0 3 0 0 3 3 3 0 Cysteine-rich KTR DUF1660 PF07874.6 EDP43562.1 - 0.39 11.0 2.1 2.4 8.5 0.0 2.7 2 1 1 3 3 3 0 Prophage protein (DUF1660) DZR PF12773.2 EDP43562.1 - 1.8 8.4 8.1 7.3 6.4 0.9 3.4 2 2 0 2 2 2 0 Double zinc ribbon Lyase_1 PF00206.15 EDP43563.1 - 6.7e-119 396.7 0.0 1.1e-118 396.0 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EDP43563.1 - 5.6e-19 67.9 0.1 1.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EDP43563.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RRM_1 PF00076.17 EDP43564.1 - 3.6e-06 26.5 0.0 5.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43564.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43564.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pescadillo_N PF06732.6 EDP43565.1 - 2.3e-116 387.9 0.2 5e-116 386.8 0.2 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 EDP43565.1 - 0.00037 20.5 0.0 0.00083 19.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BUD22 PF09073.5 EDP43566.1 - 1.3e-43 149.7 26.3 2.1e-43 149.0 18.2 1.4 1 0 0 1 1 1 1 BUD22 Pyr_redox_3 PF13738.1 EDP43567.1 - 4.7e-20 72.5 0.0 1.3e-19 71.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDP43567.1 - 1.7e-07 29.8 0.0 2.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDP43567.1 - 9.2e-07 28.0 0.0 0.00039 19.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDP43567.1 - 5.4e-06 26.3 0.0 1.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDP43567.1 - 0.00012 22.0 0.0 0.00044 20.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDP43567.1 - 0.00045 19.2 0.0 0.082 11.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDP43567.1 - 0.001 18.0 0.0 0.083 11.7 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EDP43567.1 - 0.0023 17.7 0.0 0.81 9.4 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDP43567.1 - 0.0031 17.9 0.0 0.9 9.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 EDP43568.1 - 6.6e-29 99.6 0.1 7.7e-29 99.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDP43568.1 - 8.5e-08 32.3 0.1 1.2e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDP43568.1 - 2.9e-06 27.2 0.0 0.00021 21.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EDP43568.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EDP43568.1 - 0.00023 20.8 0.1 0.00047 19.8 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDP43568.1 - 0.00095 18.7 0.2 0.004 16.7 0.1 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EDP43568.1 - 0.004 17.1 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 EDP43568.1 - 0.038 13.5 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HyaE PF07449.6 EDP43568.1 - 0.062 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 EDP43568.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin MTP18 PF10558.4 EDP43569.1 - 4.8e-49 166.0 1.2 7.3e-49 165.4 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) ACPS PF01648.15 EDP43569.1 - 0.022 14.5 0.0 0.14 12.0 0.0 2.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Exo_endo_phos PF03372.18 EDP43570.1 - 1.2e-05 25.3 5.8 0.00029 20.8 4.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ubie_methyltran PF01209.13 EDP43571.1 - 1.4e-69 233.7 0.0 6.5e-36 123.5 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDP43571.1 - 1.4e-09 37.7 0.0 5.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EDP43571.1 - 2.5e-08 34.3 0.0 8.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EDP43571.1 - 4e-08 33.6 0.0 6.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP43571.1 - 4.3e-07 30.2 0.0 9.4e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP43571.1 - 2.1e-06 27.5 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP43571.1 - 5.9e-06 26.8 0.0 1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP43571.1 - 0.00012 22.0 0.0 0.00088 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Suc_Fer-like PF06999.7 EDP43572.1 - 9.3e-22 78.1 0.4 2.6e-21 76.6 0.3 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.22 EDP43572.1 - 8e-07 28.7 1.4 8e-07 28.7 0.9 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SSB PF00436.20 EDP43573.1 - 2.8e-12 46.3 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Band_7 PF01145.20 EDP43575.1 - 2.2e-25 89.5 2.8 2.2e-25 89.5 2.0 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family Acetyltransf_3 PF13302.1 EDP43576.1 - 3.9e-09 36.7 0.0 4.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDP43576.1 - 0.00051 19.9 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDP43576.1 - 0.00053 19.9 0.0 0.006 16.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDP43576.1 - 0.0035 17.0 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein SWIB PF02201.13 EDP43577.1 - 1.5e-13 50.1 0.0 3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EDP43577.1 - 5.1e-08 32.5 0.6 3e-07 30.1 0.4 2.1 1 1 0 1 1 1 1 DEK C terminal domain Dicty_REP PF05086.7 EDP43577.1 - 0.0049 14.7 5.9 0.0061 14.3 4.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PRTP PF01366.13 EDP43577.1 - 0.014 13.4 1.4 0.014 13.3 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DDHD PF02862.12 EDP43577.1 - 0.028 14.2 3.0 0.03 14.1 2.1 1.3 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.3 EDP43577.1 - 0.04 13.6 3.6 0.059 13.0 2.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2201_N PF13203.1 EDP43577.1 - 0.046 12.8 1.4 0.066 12.3 1.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Macoilin PF09726.4 EDP43577.1 - 0.06 11.6 7.8 0.061 11.6 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein NARP1 PF12569.3 EDP43577.1 - 0.065 11.9 4.0 0.082 11.6 2.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hid1 PF12722.2 EDP43577.1 - 0.11 10.1 5.0 0.11 10.1 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec10 PF07393.6 EDP43577.1 - 0.11 10.6 4.6 0.13 10.4 3.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Tim54 PF11711.3 EDP43577.1 - 0.15 10.5 4.4 0.18 10.3 3.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0560 PF10577.4 EDP43577.1 - 0.17 10.1 8.2 0.21 9.8 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Phyto_Pns9_10 PF05878.6 EDP43577.1 - 0.26 10.2 3.7 0.42 9.5 2.6 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF3449 PF11931.3 EDP43577.1 - 0.29 10.6 8.9 0.2 11.1 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) YqfQ PF14181.1 EDP43577.1 - 0.57 10.2 7.4 0.97 9.4 5.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein DTHCT PF08070.6 EDP43577.1 - 1.1 9.9 20.0 0.072 13.7 9.7 2.2 3 0 0 3 3 2 0 DTHCT (NUC029) region Apt1 PF10351.4 EDP43577.1 - 1.3 7.8 11.9 1.5 7.5 6.2 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Presenilin PF01080.12 EDP43577.1 - 1.9 7.2 4.1 2.3 6.9 2.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2413 PF10310.4 EDP43577.1 - 2 7.1 11.1 2.8 6.6 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Vfa1 PF08432.5 EDP43577.1 - 2.7 7.9 14.8 0.23 11.4 6.9 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UBN_AB PF14075.1 EDP43577.1 - 3.2 7.3 8.7 1.1 8.8 4.1 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain CBFD_NFYB_HMF PF00808.18 EDP43578.1 - 8.7e-19 67.3 1.9 1.3e-18 66.7 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP43578.1 - 1.6e-11 44.1 0.3 2.9e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Translin PF01997.11 EDP43579.1 - 1.3e-34 119.5 0.0 1.5e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.4 EDP43579.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EDP43579.1 - 0.074 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.6 EDP43579.1 - 0.16 11.9 0.3 0.95 9.4 0.1 2.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Abhydrolase_6 PF12697.2 EDP43580.1 - 1.5e-36 126.4 0.9 1.5e-36 126.4 0.6 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP43580.1 - 9.4e-21 74.4 0.1 3.4e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP43580.1 - 1.2e-15 57.5 0.1 1.4e-14 54.0 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDP43580.1 - 5.6e-07 29.3 0.0 3.4e-05 23.5 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EDP43580.1 - 0.0002 19.9 0.0 0.00038 19.0 0.0 1.4 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 EDP43580.1 - 0.00037 20.2 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EDP43580.1 - 0.00041 19.8 0.0 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 EDP43580.1 - 0.00084 18.8 0.0 4.8 6.5 0.0 3.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EDP43580.1 - 0.00085 18.5 0.0 0.062 12.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EDP43580.1 - 0.001 18.7 0.1 0.0032 17.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase DLH PF01738.13 EDP43580.1 - 0.0043 16.3 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family UPF0227 PF05728.7 EDP43580.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 EDP43580.1 - 0.011 14.8 0.0 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 EDP43580.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 EDP43580.1 - 0.017 14.5 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EDP43580.1 - 0.027 14.0 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EDP43580.1 - 0.029 13.9 0.0 0.1 12.1 0.0 1.9 2 1 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 EDP43580.1 - 0.13 12.5 0.4 1.2 9.3 0.2 2.7 1 1 0 1 1 1 0 Thioesterase domain NPL4 PF05021.10 EDP43581.1 - 1.3e-82 277.3 0.0 1.8e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EDP43581.1 - 7.1e-50 168.4 0.5 1.1e-49 167.8 0.4 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region PPR_2 PF13041.1 EDP43582.1 - 0.043 13.7 0.4 2.7 8.0 0.0 3.1 4 0 0 4 4 4 0 PPR repeat family WEMBL PF05701.6 EDP43583.1 - 0.0001 20.9 11.5 0.00016 20.3 8.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Syntaxin PF00804.20 EDP43583.1 - 0.0066 16.6 5.9 0.014 15.5 3.6 2.0 1 1 0 1 1 1 1 Syntaxin DUF3584 PF12128.3 EDP43583.1 - 0.0093 13.3 13.5 0.013 12.8 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IncA PF04156.9 EDP43583.1 - 0.042 13.4 22.1 0.026 14.1 12.0 2.6 2 1 1 3 3 3 0 IncA protein APG6 PF04111.7 EDP43583.1 - 0.17 10.8 12.6 0.38 9.7 8.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 EDP43583.1 - 0.58 9.0 13.4 1.1 8.1 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 EDP43583.1 - 0.59 8.3 10.6 1.5 6.9 7.3 1.7 1 0 0 1 1 1 0 Transmembrane protein FHIPEP PF00771.15 EDP43583.1 - 0.98 7.6 3.1 1.8 6.8 2.1 1.4 1 1 0 1 1 1 0 FHIPEP family TPR_MLP1_2 PF07926.7 EDP43583.1 - 1.9 8.2 19.0 4 7.2 13.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EDP43583.1 - 3.1 5.5 3.0 4.7 4.9 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EDP43583.1 - 9.1 6.6 8.2 1.2e+02 3.1 5.7 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 EDP43583.1 - 9.5 4.5 5.5 14 3.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ras PF00071.17 EDP43584.1 - 4.2e-50 169.2 0.0 5.1e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP43584.1 - 1.3e-11 44.9 0.0 1.9e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP43584.1 - 6e-06 25.6 0.0 8e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_L29 PF00831.18 EDP43586.1 - 5.5e-20 70.8 3.3 5.5e-20 70.8 2.3 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein SecE PF00584.15 EDP43587.1 - 3.8e-13 48.7 0.0 4.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Img2 PF05046.9 EDP43588.1 - 1.3e-17 63.8 0.0 3.2e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Cytochrom_B561 PF03188.11 EDP43589.1 - 1.2e-15 57.5 9.6 1.2e-15 57.5 6.6 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 COX5B PF01215.14 EDP43590.1 - 1.9e-24 85.9 0.0 2.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb SH3_1 PF00018.23 EDP43591.1 - 3.7e-12 45.4 0.1 5.9e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDP43591.1 - 6.1e-11 41.7 0.0 9.1e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDP43591.1 - 2.4e-10 39.7 0.0 4.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain NTR2 PF15458.1 EDP43592.1 - 1.6e-17 63.5 16.2 7.8e-10 38.4 3.6 2.5 2 0 0 2 2 2 2 Nineteen complex-related protein 2 DUF972 PF06156.8 EDP43592.1 - 0.074 13.3 0.5 0.24 11.7 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1253 PF06862.7 EDP43593.1 - 7e-144 479.5 0.0 8.4e-144 479.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MMR_HSR1 PF01926.18 EDP43594.1 - 1.7e-16 60.2 0.0 7.1e-15 54.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP43594.1 - 2.7e-05 23.4 0.0 0.00029 20.1 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EDP43594.1 - 7.8e-05 21.9 0.0 0.0002 20.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDP43594.1 - 0.0029 17.4 0.2 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EDP43594.1 - 0.01 14.9 0.1 0.028 13.5 0.0 1.7 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EDP43594.1 - 0.056 13.9 0.0 0.22 12.0 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Peptidase_S9_N PF02897.10 EDP43595.1 - 5.1e-87 292.1 0.2 6.7e-87 291.7 0.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EDP43596.1 - 3.3e-24 85.3 0.0 3.4e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family PUA PF01472.15 EDP43597.1 - 2e-16 59.4 0.0 2.9e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF4499 PF14934.1 EDP43598.1 - 0.17 11.8 1.7 0.3 11.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) RskA PF10099.4 EDP43598.1 - 0.29 10.8 6.3 0.21 11.2 3.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Peptidase_C12 PF01088.16 EDP43599.1 - 3.5e-60 202.8 0.0 4.3e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EDP43599.1 - 0.13 12.9 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain UDG PF03167.14 EDP43600.1 - 2.2e-07 30.4 0.0 4.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PT PF04886.7 EDP43600.1 - 0.035 13.4 22.9 0.15 11.3 15.9 2.3 1 1 0 1 1 1 0 PT repeat DUF605 PF04652.11 EDP43600.1 - 0.098 12.0 17.0 0.11 11.9 11.8 1.1 1 0 0 1 1 1 0 Vta1 like Nucleo_P87 PF07267.6 EDP43600.1 - 0.32 9.6 4.2 0.36 9.4 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4106 PF13388.1 EDP43600.1 - 0.56 9.0 10.6 0.83 8.5 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ndc1_Nup PF09531.5 EDP43600.1 - 0.77 8.1 8.2 0.88 7.9 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.8 EDP43600.1 - 4.1 6.7 8.4 5.4 6.3 5.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pro_CA PF00484.14 EDP43601.1 - 4.8e-40 137.0 0.2 6.2e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 EDP43601.1 - 0.39 10.5 2.5 1.7 8.4 1.1 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family ADH_zinc_N_2 PF13602.1 EDP43602.1 - 0.019 15.8 0.0 0.02 15.7 0.0 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDP43603.1 - 2.9e-12 46.2 0.2 4.1e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Oxidored_nitro PF00148.14 EDP43603.1 - 0.0014 17.3 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.14 EDP43603.1 - 0.017 14.3 0.7 0.033 13.3 0.5 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PCMT PF01135.14 EDP43603.1 - 0.04 13.4 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polyketide_cyc PF03364.15 EDP43604.1 - 2.2e-25 89.1 0.1 2.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EDP43604.1 - 0.0035 17.5 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Prenyltransf PF01255.14 EDP43605.1 - 1.5e-72 243.3 0.0 1.8e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3844 PF12955.2 EDP43606.1 - 4.7e-27 94.0 1.3 7.9e-27 93.3 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Mito_carr PF00153.22 EDP43607.1 - 8e-31 105.6 0.8 9.4e-15 54.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Iso_dh PF00180.15 EDP43608.1 - 4.6e-66 223.1 0.0 5.5e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_88 PF07470.8 EDP43609.1 - 3.5e-16 59.1 2.5 4.7e-16 58.7 0.4 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 NapD PF03927.8 EDP43609.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 NapD protein DUF3215 PF11503.3 EDP43609.1 - 0.16 11.5 0.0 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) Init_tRNA_PT PF04179.7 EDP43610.1 - 1.9e-74 251.1 0.0 1.6e-68 231.6 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase Rotamase PF00639.16 EDP43611.1 - 2.2e-23 82.8 0.0 3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EDP43611.1 - 1.3e-18 67.3 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EDP43611.1 - 5.6e-06 26.9 0.0 8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EDP43611.1 - 1.1e-05 25.2 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 WW domain CMAS PF02353.15 EDP43613.1 - 4.8e-64 216.0 0.0 6.8e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDP43613.1 - 4.9e-15 55.6 0.0 9.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP43613.1 - 4.3e-12 46.3 0.0 3.8e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP43613.1 - 8.4e-09 35.9 0.0 2.6e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP43613.1 - 1.4e-08 34.5 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP43613.1 - 2.1e-08 34.4 0.0 5.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP43613.1 - 3e-08 33.7 0.2 1.3e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDP43613.1 - 3.8e-07 29.6 0.0 8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDP43613.1 - 7.9e-07 29.4 0.5 2.1e-06 28.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 EDP43613.1 - 0.00035 20.1 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EDP43613.1 - 0.001 18.4 0.0 0.0065 15.7 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 Apolipoprotein PF01442.13 EDP43613.1 - 0.0054 16.2 6.1 0.0084 15.6 4.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PrmA PF06325.8 EDP43613.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EDP43613.1 - 0.089 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EDP43613.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EDP43613.1 - 0.16 11.6 3.6 0.21 11.2 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Gtr1_RagA PF04670.7 EDP43615.1 - 2.4e-48 164.3 0.4 3.8e-48 163.6 0.3 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1640 PF07798.6 EDP43616.1 - 3.8e-63 212.7 4.7 4.3e-63 212.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Kinesin-related PF06548.6 EDP43616.1 - 0.0051 15.4 3.1 0.0061 15.1 2.1 1.1 1 0 0 1 1 1 1 Kinesin-related HALZ PF02183.13 EDP43616.1 - 0.093 12.4 2.6 0.6 9.8 1.8 2.3 1 1 0 1 1 1 0 Homeobox associated leucine zipper LppC PF04348.8 EDP43616.1 - 0.14 10.6 1.9 0.16 10.4 1.3 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Nup54 PF13874.1 EDP43616.1 - 0.22 11.1 2.7 0.41 10.3 1.9 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.6 EDP43616.1 - 0.39 10.6 3.2 4.4 7.2 0.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PNPOx_C PF10590.4 EDP43617.1 - 4.1e-11 42.2 0.6 7.1e-11 41.4 0.4 1.3 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EDP43617.1 - 0.008 16.1 0.0 0.071 13.1 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase HlyIII PF03006.15 EDP43618.1 - 4.3e-49 166.9 13.4 5.2e-49 166.6 9.3 1.2 1 0 0 1 1 1 1 Haemolysin-III related Ndr PF03096.9 EDP43618.1 - 0.0054 15.2 0.0 0.0074 14.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family UPF0060 PF02694.10 EDP43618.1 - 0.15 12.0 9.2 0.54 10.2 1.9 3.0 1 1 1 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Rep_fac_C PF08542.6 EDP43619.1 - 3.7e-19 68.4 0.0 6.8e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EDP43619.1 - 4.9e-12 46.1 0.0 8.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EDP43619.1 - 4.9e-11 42.5 0.0 1.1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EDP43619.1 - 3.5e-07 30.4 0.3 8.9e-06 25.8 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.1 EDP43619.1 - 3.9e-06 26.7 0.0 5.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDP43619.1 - 1.3e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP43619.1 - 7.8e-05 22.8 0.0 0.064 13.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EDP43619.1 - 0.00019 20.5 0.0 0.00044 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EDP43619.1 - 0.00024 19.9 0.0 0.02 13.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EDP43619.1 - 0.00073 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EDP43619.1 - 0.003 17.2 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDP43619.1 - 0.0034 16.5 0.1 0.039 13.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EDP43619.1 - 0.0062 16.0 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EDP43619.1 - 0.011 15.2 0.0 1.8 7.9 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain ArgK PF03308.11 EDP43619.1 - 0.02 13.6 0.0 0.061 12.0 0.0 1.7 1 1 1 2 2 2 0 ArgK protein SRP54 PF00448.17 EDP43619.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EDP43619.1 - 0.083 12.5 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 NTPase Erp_C PF06780.6 EDP43620.1 - 8.8 6.1 7.9 17 5.1 0.5 3.0 3 0 0 3 3 3 0 Erp protein C-terminus Kelch_5 PF13854.1 EDP43621.1 - 1.3e-38 130.3 6.1 2.7e-07 30.4 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EDP43621.1 - 2e-38 129.6 11.8 3.8e-09 36.4 0.0 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EDP43621.1 - 1.1e-35 121.1 16.7 5.7e-10 38.8 0.1 7.1 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EDP43621.1 - 3.8e-30 102.7 6.0 4.7e-10 39.1 0.2 6.7 3 1 3 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EDP43621.1 - 7.1e-25 86.2 4.9 3.5e-09 36.0 0.2 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EDP43621.1 - 6.4e-22 76.4 9.3 2.7e-05 23.7 0.1 6.8 6 1 0 6 6 6 5 Kelch motif CDK2AP PF09806.4 EDP43621.1 - 0.0077 16.4 2.8 0.0077 16.4 2.0 2.4 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Protamine_P2 PF00841.14 EDP43621.1 - 0.35 11.4 4.5 1.3 9.5 3.1 2.0 1 0 0 1 1 1 0 Sperm histone P2 Vsr PF03852.10 EDP43622.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr zf-BED PF02892.10 EDP43623.1 - 0.14 11.9 0.2 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger Methyltransf_31 PF13847.1 EDP43624.1 - 0.00031 20.3 0.0 0.0068 16.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF4470 PF14737.1 EDP43624.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Methyltransf_25 PF13649.1 EDP43624.1 - 0.0014 19.0 0.3 0.0055 17.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP43624.1 - 0.0072 16.7 0.1 0.058 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.15 EDP43624.1 - 0.025 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_26 PF13659.1 EDP43624.1 - 0.036 14.1 2.5 0.083 12.9 1.7 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDP43624.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDP43624.1 - 0.11 13.0 0.1 0.3 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain NAD_synthase PF02540.12 EDP43625.1 - 5.1e-26 91.0 0.0 1.8e-25 89.2 0.0 1.7 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EDP43625.1 - 1.8e-22 79.5 0.0 2.9e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EDP43625.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase adh_short PF00106.20 EDP43626.1 - 9.6e-23 80.9 0.2 1.6e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP43626.1 - 1e-06 28.5 0.2 1.6e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDP43626.1 - 2.6e-06 27.5 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EDP43626.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EDP43626.1 - 0.088 11.6 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4235 PF14019.1 EDP43626.1 - 0.15 11.9 1.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) FixP_N PF14715.1 EDP43626.1 - 3.2 7.2 5.1 5.2 6.5 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NARG2_C PF10505.4 EDP43627.1 - 0.22 10.6 0.9 6.4 5.8 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Usp PF00582.21 EDP43628.1 - 2.2e-05 24.6 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Glyco_transf_20 PF00982.16 EDP43629.1 - 1.2e-180 601.0 0.0 8.9e-136 453.1 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Arginosuc_synth PF00764.14 EDP43630.1 - 1.6e-156 521.2 0.0 1.8e-156 521.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EDP43630.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EDP43630.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EDP43630.1 - 0.033 12.7 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Ish1 PF10281.4 EDP43630.1 - 0.17 11.9 0.2 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PUF PF00806.14 EDP43631.1 - 5.2e-08 31.9 0.0 0.00025 20.3 0.0 4.4 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat TTL PF03133.10 EDP43632.1 - 7.2e-38 130.1 0.0 4.2e-37 127.6 0.0 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EDP43632.1 - 0.0026 17.4 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Sec7 PF01369.15 EDP43633.1 - 7.1e-29 100.8 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain UMP1 PF05348.6 EDP43633.1 - 0.036 14.0 0.7 3.8 7.4 0.2 2.5 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 zf-C2H2 PF00096.21 EDP43634.1 - 1.1e-19 69.4 41.9 0.00037 20.6 1.8 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP43634.1 - 2.8e-19 67.9 41.0 0.0047 17.1 0.8 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDP43634.1 - 9.2e-06 25.7 0.0 9.2e-06 25.7 0.0 7.3 8 1 0 8 8 8 3 Zinc-finger double domain BolA PF01722.13 EDP43634.1 - 0.048 13.6 0.3 6.1 6.8 0.2 3.2 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_6 PF13912.1 EDP43634.1 - 0.078 12.9 9.5 0.28 11.1 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 EDP43634.1 - 0.24 11.6 0.1 0.24 11.6 0.1 5.6 6 1 0 6 6 6 0 Zinc-finger of C2H2 type FYVE PF01363.16 EDP43634.1 - 0.82 9.6 21.0 1.6 8.7 2.0 3.7 2 1 1 3 3 3 0 FYVE zinc finger zf-C2H2_jaz PF12171.3 EDP43634.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EDP43634.1 - 3.3 8.1 29.7 7.8 6.9 0.0 7.2 7 0 0 7 7 7 0 C2H2-type zinc-finger domain RRM_1 PF00076.17 EDP43635.1 - 1.4e-33 114.3 0.1 3.9e-20 71.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43635.1 - 7.8e-28 96.2 0.0 3.1e-16 59.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43635.1 - 2.6e-20 71.9 0.0 1.2e-08 34.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EDP43635.1 - 4.4e-10 39.7 0.1 1.1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EDP43635.1 - 0.00048 19.9 0.1 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EDP43635.1 - 0.014 15.1 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 EDP43636.1 - 3.9e-08 32.8 9.3 0.00055 19.7 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDP43636.1 - 0.11 12.2 3.0 7.6 6.2 0.0 3.8 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 EDP43636.1 - 0.17 11.5 1.4 5.4 6.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glycos_transf_1 PF00534.15 EDP43637.1 - 2e-32 111.9 0.0 1e-31 109.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDP43637.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDP43637.1 - 0.0021 18.2 2.8 0.1 12.9 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDP43637.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Rifin_STEVOR PF02009.11 EDP43637.1 - 0.12 12.0 0.9 0.38 10.3 0.7 1.7 2 0 0 2 2 2 0 Rifin/stevor family BING4CT PF08149.6 EDP43638.1 - 9.1e-37 124.4 0.0 1.1e-35 120.9 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EDP43638.1 - 2.2e-07 30.5 0.0 2.4e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EDP43638.1 - 1.2e-05 24.2 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region ABC_tran PF00005.22 EDP43639.1 - 7.6e-15 55.4 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDP43639.1 - 9.2e-09 35.6 0.7 0.0012 18.8 0.3 2.2 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDP43639.1 - 3.2e-05 23.1 0.0 0.071 12.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDP43639.1 - 0.00026 20.4 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EDP43639.1 - 0.0042 16.5 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDP43639.1 - 0.0052 16.7 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EDP43639.1 - 0.0062 15.7 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDP43639.1 - 0.0069 17.1 0.1 0.012 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDP43639.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDP43639.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EDP43639.1 - 0.049 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EDP43639.1 - 0.07 12.5 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Arf PF00025.16 EDP43639.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_23 PF13476.1 EDP43639.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDP43639.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDP43639.1 - 0.1 12.7 0.2 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDP43639.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EDP43639.1 - 0.15 11.8 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EDP43639.1 - 0.17 12.3 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 EDP43639.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 EDP43640.1 - 4.1e-41 140.5 0.1 5.1e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRK PF00485.13 EDP43641.1 - 1.9e-48 164.5 0.0 2.7e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EDP43641.1 - 5.4e-41 140.0 0.0 3.3e-38 130.9 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EDP43641.1 - 3.3e-05 24.1 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP43641.1 - 0.00095 19.9 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EDP43641.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EDP43641.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 EDP43641.1 - 0.16 11.3 1.7 0.95 8.8 1.2 2.1 1 1 0 1 1 1 0 Dephospho-CoA kinase DUF2985 PF11204.3 EDP43642.1 - 3.4e-25 87.6 6.0 5.6e-25 86.8 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF3139 PF11337.3 EDP43642.1 - 0.094 13.0 0.3 27 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Molybdopterin PF00384.17 EDP43643.1 - 1.5e-68 231.5 0.0 1e-65 222.1 0.0 2.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EDP43643.1 - 2.6e-17 61.7 0.0 7.4e-17 60.3 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EDP43643.1 - 9.9e-17 60.5 0.0 2.3e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 EDP43643.1 - 1.3e-13 50.8 0.1 3.1e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EDP43643.1 - 2.4e-09 36.8 0.4 5.9e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EDP43643.1 - 0.0011 18.7 0.3 0.097 12.4 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EDP43643.1 - 0.17 11.5 1.7 6.9 6.4 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain zf-RING_4 PF14570.1 EDP43643.1 - 0.39 10.3 3.7 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Arf PF00025.16 EDP43644.1 - 1.6e-18 66.5 0.1 5.4e-18 64.8 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDP43644.1 - 3.3e-05 23.1 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EDP43644.1 - 5.2e-05 22.1 0.0 0.07 11.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EDP43644.1 - 7.1e-05 23.2 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EDP43644.1 - 0.0027 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EDP43644.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDP43644.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDP43644.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 EDP43644.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.5 1 1 0 1 1 1 0 Ras family GTP_EFTU PF00009.22 EDP43644.1 - 0.07 12.5 0.0 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ICE2 PF08426.5 EDP43645.1 - 1.3e-20 73.4 4.6 8.4e-20 70.7 2.9 2.1 1 1 0 1 1 1 1 ICE2 RRS1 PF04939.7 EDP43646.1 - 2e-55 186.7 4.9 3e-55 186.1 3.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) WD40 PF00400.27 EDP43647.1 - 3.4e-39 131.3 15.3 8e-12 44.5 0.1 7.4 8 1 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EDP43647.1 - 0.0002 20.8 0.4 0.13 11.6 0.0 3.5 3 1 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EDP43647.1 - 0.0014 17.0 0.0 0.13 10.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EDP43647.1 - 0.011 13.8 0.2 0.53 8.3 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EDP43647.1 - 0.015 15.1 0.0 0.26 11.0 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ribul_P_3_epim PF00834.14 EDP43648.1 - 5.8e-64 214.9 0.0 7.4e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 EDP43648.1 - 0.0047 16.8 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Predicted Peptidoglycan domain QRPTase_C PF01729.14 EDP43648.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 EDP43648.1 - 0.084 12.1 0.2 0.49 9.6 0.0 2.1 1 1 1 2 2 2 0 PcrB family Peptidase_A22B PF04258.8 EDP43649.1 - 1.1e-68 231.9 8.4 1.4e-68 231.5 5.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EDP43649.1 - 0.00093 18.4 7.3 0.0011 18.2 3.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) HILPDA PF15220.1 EDP43649.1 - 10 6.2 6.9 2.7 8.0 0.5 2.7 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated MIF4G PF02854.14 EDP43650.1 - 4.7e-21 75.1 0.1 7.6e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EDP43650.1 - 6.3e-07 29.0 0.1 3.9e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 MA3 domain Sigma70_ner PF04546.8 EDP43650.1 - 0.074 12.6 10.8 0.46 10.0 7.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 EDP43650.1 - 4.5 6.4 22.4 8 5.6 15.5 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EDP43650.1 - 5 4.9 29.5 0.45 8.3 17.1 1.6 2 0 0 2 2 2 0 Nop14-like family DEAD PF00270.24 EDP43651.1 - 3e-41 140.7 0.1 1.1e-40 138.9 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43651.1 - 5.7e-26 90.1 0.4 1.4e-25 88.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDP43651.1 - 1e-05 24.5 0.0 1.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDP43651.1 - 2.6e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EDP43651.1 - 0.00034 19.1 0.0 0.32 9.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EDP43651.1 - 0.0015 18.6 0.2 0.0068 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain Herpes_ori_bp PF02399.10 EDP43651.1 - 0.0069 14.4 0.0 0.011 13.7 0.0 1.2 1 0 0 1 1 1 1 Origin of replication binding protein AAA_19 PF13245.1 EDP43651.1 - 0.0084 15.8 0.7 0.059 13.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain T4SS-DNA_transf PF02534.9 EDP43651.1 - 0.087 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF2075 PF09848.4 EDP43651.1 - 0.11 11.4 0.2 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Spc7 PF08317.6 EDP43652.1 - 4.9e-35 120.7 0.1 7.8e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Inhibitor_I42 PF09394.5 EDP43652.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 TBPIP PF07106.8 EDP43652.1 - 0.73 9.3 4.1 19 4.7 2.3 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Dus PF01207.12 EDP43653.1 - 6.5e-34 117.1 0.1 8.5e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PapG_C PF03628.8 EDP43653.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PapG chaperone-binding domain Rad60-SLD_2 PF13881.1 EDP43654.1 - 0.00058 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDP43654.1 - 0.0033 16.7 0.0 0.0094 15.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family VPS28 PF03997.7 EDP43655.1 - 1.6e-36 125.7 0.0 1.9e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EDP43655.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Proteasome PF00227.21 EDP43658.1 - 5.4e-45 153.0 0.0 6.7e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDP43658.1 - 3.8e-13 48.4 0.3 8.1e-13 47.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MSC PF09402.5 EDP43660.1 - 5.4e-56 189.7 0.0 7.3e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EDP43660.1 - 6.7e-14 51.1 0.0 1.3e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 EDP43660.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 SAP domain zf-DHHC PF01529.15 EDP43661.1 - 1.4e-33 115.6 1.2 2.5e-33 114.9 0.8 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase RIO1 PF01163.17 EDP43662.1 - 1.3e-40 138.7 0.3 1.7e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EDP43662.1 - 7.5e-33 112.4 0.1 1.8e-32 111.2 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EDP43662.1 - 6.4e-08 32.6 2.2 3.9e-05 23.5 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDP43662.1 - 0.00024 20.2 0.3 0.0083 15.2 0.2 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 EDP43662.1 - 0.0021 17.6 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 MarR family E1_DerP2_DerF2 PF02221.10 EDP43663.1 - 7.8e-17 61.7 0.0 9.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EDP43663.1 - 0.00017 21.5 0.0 0.00064 19.7 0.0 1.8 1 1 0 1 1 1 1 ML-like domain Mre11_DNA_bind PF04152.9 EDP43664.1 - 2.1e-38 131.9 0.0 3.2e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EDP43664.1 - 1.5e-14 53.9 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDP43664.1 - 5.9e-05 22.9 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rcd1 PF04078.8 EDP43665.1 - 6.8e-128 425.0 0.7 8.5e-128 424.7 0.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like cwf21 PF08312.7 EDP43666.1 - 2e-16 59.5 7.5 2e-16 59.5 5.2 2.2 2 0 0 2 2 2 1 cwf21 domain Pex14_N PF04695.8 EDP43666.1 - 0.65 10.0 5.4 0.11 12.5 0.6 1.8 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PMM PF03332.8 EDP43667.1 - 9.8e-104 345.7 0.2 1.1e-103 345.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EDP43667.1 - 6.4e-06 25.9 0.0 5.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDP43667.1 - 0.0037 16.6 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EDP43667.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EDP43667.1 - 0.063 12.3 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Hydrolase PF00702.21 EDP43667.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PPR_2 PF13041.1 EDP43670.1 - 1.7e-31 107.9 0.5 9.5e-08 31.9 0.0 8.5 8 1 1 9 9 9 6 PPR repeat family PPR PF01535.15 EDP43670.1 - 1.3e-18 65.5 0.1 1.7e-05 24.4 0.0 6.4 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EDP43670.1 - 4.9e-17 61.1 0.4 0.0017 17.7 0.0 5.5 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.1 EDP43670.1 - 6.8e-16 57.1 22.0 0.0033 17.5 0.4 10.0 10 0 0 10 10 10 5 Pentatricopeptide repeat domain RPM2 PF08579.6 EDP43670.1 - 0.0096 16.0 0.1 19 5.3 0.0 4.0 2 1 2 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) Acetyltransf_1 PF00583.19 EDP43671.1 - 2.7e-06 27.3 0.1 6.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDP43671.1 - 4.3e-06 26.7 0.0 2.2e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EDP43671.1 - 0.00045 20.7 0.1 0.0087 16.6 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDP43671.1 - 0.00047 20.2 0.0 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EDP43671.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FR47 PF08445.5 EDP43671.1 - 0.087 12.5 0.3 1.1 9.1 0.2 2.2 1 1 0 1 1 1 0 FR47-like protein CHCH PF06747.8 EDP43672.1 - 0.0068 16.2 0.4 0.0096 15.8 0.2 1.2 1 0 0 1 1 1 1 CHCH domain Sec61_beta PF03911.11 EDP43673.1 - 4.1e-14 52.1 0.1 5.9e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 Sec61beta family Baculo_11_kDa PF06143.6 EDP43673.1 - 0.25 10.7 2.8 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family Svf1 PF08622.5 EDP43674.1 - 6.9e-77 258.5 0.0 7.9e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Hus1 PF04005.7 EDP43675.1 - 2.2e-51 174.5 0.3 2.9e-51 174.1 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Lipocalin_6 PF13944.1 EDP43675.1 - 0.08 13.0 0.2 9.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Lipocalin-like domain Yae1_N PF09811.4 EDP43677.1 - 1.5e-07 30.7 11.8 2.1e-07 30.3 8.2 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1631 PF07793.6 EDP43677.1 - 0.011 13.8 0.2 0.013 13.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Cation_efflux PF01545.16 EDP43678.1 - 6.1e-35 120.6 7.2 9.2e-35 120.0 5.0 1.2 1 0 0 1 1 1 1 Cation efflux family CENP-X PF09415.5 EDP43678.1 - 0.012 15.3 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X ESSS PF10183.4 EDP43679.1 - 0.00035 20.9 0.3 0.0004 20.7 0.1 1.2 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PH PF00169.24 EDP43680.1 - 7.9e-27 93.4 0.0 2.2e-12 47.1 0.0 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EDP43680.1 - 6.3e-14 52.1 4.8 7.4e-06 26.1 2.0 4.3 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 EDP43680.1 - 8.6e-10 38.4 0.7 0.0013 18.6 0.1 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 EDP43680.1 - 5.1e-09 36.0 2.7 2.6e-06 27.3 0.6 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EDP43680.1 - 7.8e-08 32.2 1.3 0.00038 20.3 0.2 2.6 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 EDP43680.1 - 1.1 9.4 4.6 2.3 8.3 1.3 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain TPR_19 PF14559.1 EDP43681.1 - 0.00078 19.7 0.4 1.6 9.1 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDP43681.1 - 0.0077 15.8 1.9 0.57 9.8 0.0 3.8 4 1 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 EDP43681.1 - 0.13 12.9 10.2 9.2 7.2 0.5 5.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43681.1 - 1.3 9.7 4.8 2.2 9.0 0.3 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat UreF PF01730.11 EDP43681.1 - 3 7.9 10.0 1e+02 2.9 5.5 3.2 2 2 1 3 3 3 0 UreF zf-CCCH PF00642.19 EDP43682.1 - 1.4e-10 40.6 26.8 0.00024 20.7 0.6 4.2 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Viral_cys_rich PF08008.7 EDP43682.1 - 1.1 8.8 5.0 6.3 6.4 0.0 2.9 2 1 1 3 3 3 0 Viral cysteine rich HECT PF00632.20 EDP43683.1 - 5.7e-16 58.5 0.0 9.2e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PRT_C PF08372.5 EDP43684.1 - 0.015 14.8 0.3 0.036 13.5 0.2 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Med19 PF10278.4 EDP43684.1 - 0.022 14.4 13.3 0.055 13.1 9.2 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3292 PF11696.3 EDP43684.1 - 0.051 11.4 14.8 0.089 10.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3292) Reticulon PF02453.12 EDP43684.1 - 0.096 12.2 6.2 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Reticulon NAP PF00956.13 EDP43685.1 - 1.1e-32 113.1 14.8 1.8e-31 109.1 10.3 2.0 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 EDP43685.1 - 0.13 11.2 12.3 0.18 10.8 8.5 1.2 1 0 0 1 1 1 0 BUD22 Retinal PF15449.1 EDP43685.1 - 0.87 7.1 4.0 1.2 6.7 2.8 1.2 1 0 0 1 1 1 0 Retinal protein YL1 PF05764.8 EDP43685.1 - 3.7 7.0 16.7 5.8 6.4 11.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein ANAPC15 PF15243.1 EDP43685.1 - 6.6 6.8 20.3 15 5.7 8.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.9 EDP43685.1 - 8.1 4.3 10.0 11 3.8 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 EDP43685.1 - 8.6 6.5 18.1 1.6 8.9 7.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) C2 PF00168.25 EDP43686.1 - 1.9e-36 123.7 0.0 4.2e-14 52.1 0.0 4.4 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 EDP43686.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Ank_2 PF12796.2 EDP43687.1 - 3.2e-28 97.9 0.3 2.7e-20 72.4 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDP43687.1 - 2.1e-15 55.6 8.0 2.5e-06 27.0 0.2 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EDP43687.1 - 1.1e-13 49.9 0.7 0.011 15.9 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EDP43687.1 - 3.1e-13 49.8 0.5 3.3e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP43687.1 - 5.7e-09 35.9 2.4 0.00039 20.5 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Arm PF00514.18 EDP43688.1 - 7.5e-93 301.5 11.8 5.2e-13 48.2 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDP43688.1 - 1.8e-23 82.6 0.3 1.2e-07 31.8 0.0 5.9 1 1 5 6 6 6 6 HEAT repeats IBB PF01749.15 EDP43688.1 - 1.3e-22 79.7 7.8 2.1e-22 79.0 5.4 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EDP43688.1 - 2.3e-19 69.2 2.6 6e-07 29.7 0.0 6.1 7 0 0 7 7 6 2 HEAT-like repeat HEAT PF02985.17 EDP43688.1 - 1.8e-16 58.6 0.7 0.00059 19.7 0.0 6.9 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.8 EDP43688.1 - 1.4e-07 30.8 0.0 0.031 13.4 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EDP43688.1 - 0.00023 19.6 0.0 0.0033 15.8 0.0 2.5 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EDP43688.1 - 0.00073 19.4 0.1 0.87 9.5 0.0 4.3 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 EDP43688.1 - 0.0031 17.3 6.1 0.44 10.4 0.0 4.6 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EDP43688.1 - 0.015 13.5 0.1 0.41 8.8 0.0 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EDP43688.1 - 0.053 13.9 4.3 0.98 10.0 0.0 4.4 6 0 0 6 6 3 0 PBS lyase HEAT-like repeat Mo25 PF08569.6 EDP43688.1 - 0.054 12.5 0.0 0.14 11.1 0.0 1.7 1 0 0 1 1 1 0 Mo25-like PRP3 PF08572.5 EDP43689.1 - 1.2e-41 142.5 6.3 1.8e-41 141.9 4.4 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EDP43689.1 - 1.5e-33 115.2 0.0 3.8e-33 113.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PAT1 PF09770.4 EDP43689.1 - 0.24 9.5 3.1 0.33 9.1 2.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAUB PF08164.7 EDP43690.1 - 3.9e-21 74.9 0.0 3.9e-21 74.9 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EDP43690.1 - 5.4e-17 62.1 0.5 5.4e-17 62.1 0.3 3.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor GTP_cyclohydro2 PF00925.15 EDP43691.1 - 3.6e-61 205.2 0.1 3.9e-55 185.6 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II LRR_6 PF13516.1 EDP43692.1 - 8e-07 28.4 2.8 2.4 8.4 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 EDP43692.1 - 1.3e-05 24.5 3.2 2.2 8.8 0.0 5.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EDP43692.1 - 7e-05 22.3 3.4 0.019 14.5 0.1 4.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDP43692.1 - 0.00012 21.6 5.0 2.4 8.5 0.0 6.0 5 0 0 5 5 5 1 Leucine Rich Repeat Abhydrolase_5 PF12695.2 EDP43693.1 - 3.8e-16 59.1 0.0 5.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP43693.1 - 1.2e-11 44.8 0.0 1.9e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDP43693.1 - 2.9e-09 36.8 0.0 4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EDP43693.1 - 3.3e-05 23.5 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDP43693.1 - 0.041 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase GIT_SHD PF08518.6 EDP43693.1 - 0.094 12.0 1.1 0.25 10.7 0.8 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT DUF676 PF05057.9 EDP43693.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) tRNA-synt_2d PF01409.15 EDP43694.1 - 5.5e-47 160.0 0.0 3.3e-25 88.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EDP43694.1 - 1.1e-25 89.6 0.0 2.3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF4404 PF14357.1 EDP43695.1 - 0.7 10.3 4.0 5.4 7.4 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DOT1 PF08123.8 EDP43696.1 - 5.4e-37 127.0 0.0 8.1e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EDP43696.1 - 0.11 12.5 0.5 0.38 10.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain DUF3439 PF11921.3 EDP43696.1 - 0.25 11.1 1.5 0.49 10.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EDP43696.1 - 4.8 6.9 8.3 9.6 5.9 5.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.20 EDP43697.1 - 5.9e-69 232.1 0.0 8.4e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43697.1 - 1.2e-30 106.4 0.0 1.9e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43697.1 - 8.7e-07 28.1 0.0 2.7e-06 26.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EDP43697.1 - 0.00028 20.0 1.0 0.00036 19.6 0.1 1.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDP43697.1 - 0.0053 16.1 1.8 0.0084 15.4 0.0 2.0 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL APH PF01636.18 EDP43697.1 - 0.047 13.4 2.3 0.1 12.3 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family PigN PF04987.9 EDP43698.1 - 2.7e-46 158.1 14.0 3.9e-46 157.6 9.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EDP43698.1 - 6.4e-12 45.4 0.9 2.8e-09 36.7 0.0 3.0 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDP43698.1 - 0.00054 19.2 0.1 0.00086 18.5 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EDP43698.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF3819 PF12842.2 EDP43699.1 - 1.7e-54 183.5 3.3 1.1e-53 180.8 1.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Not1 PF04054.10 EDP43699.1 - 4.7e-47 160.6 1.4 1.1e-33 116.6 0.0 2.7 2 0 0 2 2 2 2 CCR4-Not complex component, Not1 ABC_tran PF00005.22 EDP43700.1 - 1.9e-46 157.7 0.0 1e-27 97.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDP43700.1 - 2.9e-46 158.1 19.6 7.2e-24 84.6 4.5 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 EDP43700.1 - 4.6e-10 39.7 0.7 0.0015 18.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EDP43700.1 - 6.7e-09 35.2 1.9 0.0026 17.0 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP43700.1 - 7.5e-07 29.3 2.6 0.27 11.1 0.6 4.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EDP43700.1 - 3.7e-06 26.4 0.1 0.066 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDP43700.1 - 3.9e-06 26.2 0.2 0.03 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDP43700.1 - 3.2e-05 24.0 0.3 0.66 10.1 0.1 4.0 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDP43700.1 - 0.00012 21.6 1.7 0.74 9.1 0.2 3.0 2 1 1 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 EDP43700.1 - 0.0021 18.0 0.2 1.2 9.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EDP43700.1 - 0.0036 16.2 0.1 0.58 9.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 EDP43700.1 - 0.0043 16.9 0.1 5 7.0 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EDP43700.1 - 0.0046 16.6 0.2 0.18 11.5 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDP43700.1 - 0.0075 15.7 0.0 1.2 8.5 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EDP43700.1 - 0.0091 15.8 1.7 0.17 11.6 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_23 PF13476.1 EDP43700.1 - 0.017 15.4 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDP43700.1 - 0.021 15.6 0.2 0.63 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EDP43700.1 - 0.025 15.0 0.3 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EDP43700.1 - 0.029 14.0 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDP43700.1 - 0.031 13.4 0.1 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDP43700.1 - 0.057 13.2 0.4 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF2826 PF11442.3 EDP43700.1 - 0.067 12.8 3.0 0.61 9.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2826) NACHT PF05729.7 EDP43700.1 - 0.1 12.2 0.5 21 4.6 0.0 3.7 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.1 EDP43700.1 - 0.14 12.0 2.8 5.5 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EDP43700.1 - 0.19 12.0 0.9 5 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDP43700.1 - 0.27 10.8 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EDP43700.1 - 0.53 9.7 1.7 4 6.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PAC2 PF09754.4 EDP43701.1 - 2.1e-09 37.5 0.0 1.2e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 PAC2 family MutS_V PF00488.16 EDP43702.1 - 3.9e-74 248.9 0.0 9.4e-74 247.7 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EDP43702.1 - 1.8e-43 148.7 6.8 3.5e-43 147.7 4.7 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDP43702.1 - 2.3e-23 82.3 0.0 5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EDP43702.1 - 4e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EDP43702.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EDP43703.1 - 3.8e-47 160.0 0.0 1.2e-27 96.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDP43703.1 - 2.1e-42 145.4 41.0 8.2e-23 81.1 9.9 3.8 3 1 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDP43703.1 - 5.6e-10 38.8 3.7 0.0041 16.3 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP43703.1 - 1.4e-06 28.5 2.5 0.32 10.9 0.6 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDP43703.1 - 1.6e-06 27.5 0.1 0.034 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EDP43703.1 - 2.3e-06 27.7 0.3 0.0021 18.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EDP43703.1 - 5.4e-05 22.6 0.1 0.46 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDP43703.1 - 0.00012 22.1 0.5 0.79 9.8 0.1 4.1 3 1 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EDP43703.1 - 0.0004 19.9 1.1 1.4 8.3 0.1 3.0 2 1 1 3 3 3 2 AAA-like domain SbcCD_C PF13558.1 EDP43703.1 - 0.0015 18.4 0.2 1.7 8.5 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EDP43703.1 - 0.0021 17.0 0.1 0.69 8.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EDP43703.1 - 0.003 17.5 0.1 1.4 8.8 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EDP43703.1 - 0.012 15.1 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EDP43703.1 - 0.014 16.1 2.7 0.73 10.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EDP43703.1 - 0.018 14.7 0.9 3.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EDP43703.1 - 0.018 14.1 0.7 1.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 EDP43703.1 - 0.023 15.1 0.5 12 6.4 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EDP43703.1 - 0.027 13.6 0.1 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDP43703.1 - 0.058 13.7 6.3 2.2 8.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 EDP43703.1 - 0.12 12.2 0.0 28 4.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EDP43703.1 - 0.14 11.9 1.5 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EDP43703.1 - 0.22 11.8 0.6 5.8 7.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EDP43703.1 - 0.31 10.8 3.8 0.87 9.3 0.0 3.0 3 0 0 3 3 3 0 Dynamin family cobW PF02492.14 EDP43703.1 - 0.4 10.0 1.0 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1279 PF06916.8 EDP43704.1 - 9.9e-18 64.2 0.1 2.2e-17 63.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Ribosomal_S14 PF00253.16 EDP43705.1 - 3.9e-19 67.7 6.2 4.3e-19 67.6 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e A2L_zn_ribbon PF08792.5 EDP43705.1 - 0.07 12.6 2.2 0.1 12.0 1.5 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF4428 PF14471.1 EDP43705.1 - 0.071 12.8 0.8 0.095 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) HypA PF01155.14 EDP43705.1 - 0.16 11.6 0.3 0.19 11.4 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 EDP43705.1 - 0.48 10.3 4.0 0.67 9.8 2.8 1.3 1 1 0 1 1 1 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.7 EDP43705.1 - 1.1 9.3 6.5 6.6 6.9 1.2 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Abhydrolase_5 PF12695.2 EDP43706.1 - 4.8e-11 42.5 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDP43706.1 - 3.7e-06 25.9 0.0 6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EDP43706.1 - 0.00086 18.5 0.0 0.0024 17.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EDP43706.1 - 0.0045 16.5 0.1 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aminotran_4 PF01063.14 EDP43707.1 - 5e-24 85.0 0.0 7.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV WD40 PF00400.27 EDP43708.1 - 1.5e-11 43.6 7.9 0.018 14.9 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EDP43708.1 - 0.0051 16.3 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain DAGK_cat PF00781.19 EDP43708.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DEAD PF00270.24 EDP43709.1 - 2e-41 141.2 0.0 2.1e-40 137.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43709.1 - 1.1e-26 92.4 0.0 6.6e-26 89.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ELL PF10390.4 EDP43709.1 - 0.0053 16.0 7.2 0.0085 15.3 5.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL CMS1 PF14617.1 EDP43709.1 - 0.081 11.9 0.0 0.081 11.9 0.0 3.1 2 2 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ycf1 PF05758.7 EDP43709.1 - 0.34 8.5 9.2 0.46 8.1 6.4 1.2 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 EDP43709.1 - 0.44 8.9 27.9 0.65 8.4 19.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2722 PF10846.3 EDP43709.1 - 0.5 9.3 14.7 0.79 8.6 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2413 PF10310.4 EDP43709.1 - 2.1 7.0 18.9 3.6 6.2 13.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CH PF00307.26 EDP43710.1 - 4e-67 223.0 0.3 1.3e-17 63.7 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EDP43710.1 - 1.4e-08 34.2 0.0 0.065 12.9 0.0 4.5 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 EDP43710.1 - 4.5e-05 23.5 1.6 0.00023 21.2 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDP43710.1 - 0.00076 18.6 0.8 0.019 14.2 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EDP43710.1 - 0.046 13.6 2.8 5.2 7.2 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_5 PF13202.1 EDP43710.1 - 5.4 6.5 5.9 3.5 7.1 0.1 3.2 3 0 0 3 3 3 0 EF hand Na_sulph_symp PF00939.14 EDP43711.1 - 2.3e-31 109.2 37.0 3.1e-31 108.7 25.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 EDP43711.1 - 1e-20 74.6 0.0 1.7e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.11 EDP43711.1 - 2.4e-15 56.0 32.0 5e-13 48.3 8.1 2.2 1 1 1 2 2 2 2 Citrate transporter Mito_carr PF00153.22 EDP43712.1 - 1.6e-55 184.7 0.9 1.8e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 EDP43712.1 - 0.094 12.8 0.2 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family PseudoU_synth_1 PF01416.15 EDP43713.1 - 1.7e-25 89.4 0.0 5.7e-14 52.4 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase SET PF00856.23 EDP43714.1 - 2.6e-09 37.6 0.0 8.9e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 SET domain AIF_C PF14721.1 EDP43714.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RRM_1 PF00076.17 EDP43715.1 - 1.5e-14 53.3 0.0 1.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43715.1 - 7.2e-11 41.9 0.0 8.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43715.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP43715.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NUDIX PF00293.23 EDP43716.1 - 2.1e-26 92.1 0.0 2.9e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain PCI_Csn8 PF10075.4 EDP43717.1 - 5.5e-24 84.5 0.0 7.9e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDP43717.1 - 1.1e-23 83.8 0.1 1.5e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDT PF00800.13 EDP43718.1 - 9.1e-49 165.4 0.3 1.2e-48 165.0 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Asp PF00026.18 EDP43719.1 - 8.2e-47 159.9 1.0 2.7e-46 158.2 0.7 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP43719.1 - 6.4e-10 39.3 0.5 8.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDP43719.1 - 0.00016 21.2 0.1 0.00037 20.0 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EDP43719.1 - 0.022 14.5 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 EDP43719.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DAHP_synth_2 PF01474.11 EDP43720.1 - 2.3e-178 593.1 0.0 2.5e-178 592.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Sec34 PF04136.10 EDP43721.1 - 4.2e-17 62.2 4.5 2.1e-16 60.0 1.4 2.2 1 1 0 2 2 2 1 Sec34-like family Adeno_E3B PF03376.9 EDP43721.1 - 0.054 13.3 0.1 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3B protein Ribosomal_L6 PF00347.18 EDP43724.1 - 9.1e-24 83.7 1.3 9.5e-12 45.2 0.1 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L37e PF01907.14 EDP43725.1 - 3.7e-23 81.0 13.6 6.5e-23 80.2 9.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EDP43725.1 - 0.0026 17.5 3.6 0.0041 16.9 2.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF1462 PF07315.6 EDP43725.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) SelR PF01641.13 EDP43725.1 - 0.051 13.2 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 SelR domain LIM PF00412.17 EDP43725.1 - 0.24 11.4 4.4 0.39 10.8 3.0 1.4 1 1 0 1 1 1 0 LIM domain HypA PF01155.14 EDP43725.1 - 0.34 10.6 1.6 0.43 10.2 1.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C3HC4 PF00097.20 EDP43725.1 - 0.78 9.4 6.3 1.2 8.8 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 EDP43725.1 - 4.4 6.7 11.1 6.1 6.2 1.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ribosomal_L7Ae PF01248.21 EDP43726.1 - 3.3e-21 74.5 0.0 4.2e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 EDP43726.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Cyclin_N PF00134.18 EDP43727.1 - 1e-36 125.2 1.7 1.6e-36 124.6 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDP43727.1 - 4.3e-10 39.5 0.1 1.2e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-LYAR PF08790.6 EDP43728.1 - 1.2e-09 37.6 1.5 3.3e-09 36.2 1.1 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger BssC_TutF PF08201.6 EDP43728.1 - 0.53 9.8 3.6 0.65 9.5 1.0 2.2 2 1 0 2 2 2 0 BssC/TutF protein MBF1 PF08523.5 EDP43729.1 - 1.8e-12 47.1 0.1 3.9e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EDP43729.1 - 2.1e-11 43.4 0.2 3.5e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EDP43729.1 - 1.3e-05 25.1 0.1 1.8e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EDP43729.1 - 3.3e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.20 EDP43730.1 - 2e-61 207.3 0.0 2.6e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43730.1 - 5.5e-32 110.8 0.0 6.7e-30 104.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43730.1 - 2e-08 33.5 0.0 2.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP43730.1 - 0.11 12.1 0.3 1.1 8.9 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDP43730.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase I-set PF07679.11 EDP43731.1 - 0.02 14.7 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Immunoglobulin I-set domain JAB PF01398.16 EDP43732.1 - 4.3e-17 61.8 0.0 7.7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDP43732.1 - 2.9e-10 40.2 0.0 6.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Methyltransf_4 PF02390.12 EDP43733.1 - 8.8e-55 184.8 0.0 1e-40 138.9 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EDP43733.1 - 6.6e-05 23.4 0.1 0.00025 21.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP43733.1 - 0.00027 20.9 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP43733.1 - 0.0016 18.8 0.0 0.005 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP43733.1 - 0.0022 18.3 0.0 0.0068 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDP43733.1 - 0.0085 15.4 0.0 0.081 12.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EDP43733.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EDP43733.1 - 0.041 13.6 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EDP43733.1 - 0.042 13.4 0.0 0.51 9.9 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDP43733.1 - 0.044 14.2 0.0 3.1 8.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EDP43733.1 - 0.061 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Prefoldin_2 PF01920.15 EDP43734.1 - 2e-16 59.6 3.1 2.2e-16 59.5 2.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EDP43734.1 - 0.072 12.7 1.7 0.45 10.1 1.2 1.9 1 1 0 1 1 1 0 Prefoldin subunit FliJ PF02050.11 EDP43734.1 - 0.1 12.6 1.7 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein UBN2 PF14223.1 EDP43734.1 - 0.14 11.9 1.3 0.91 9.3 0.1 2.2 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF641 PF04859.7 EDP43734.1 - 0.43 10.3 4.5 0.99 9.1 0.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 EDP43734.1 - 0.71 10.2 3.6 3.8 7.9 0.3 2.3 2 1 1 3 3 3 0 SlyX DUF812 PF05667.6 EDP43734.1 - 1.1 7.6 4.5 4.1 5.7 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) PC_rep PF01851.17 EDP43735.1 - 0.0019 18.3 0.1 0.041 14.1 0.0 3.0 3 0 0 3 3 3 1 Proteasome/cyclosome repeat DUF445 PF04286.7 EDP43735.1 - 0.01 15.3 0.4 0.023 14.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PC_rep PF01851.17 EDP43736.1 - 9.7e-27 91.6 15.5 1.5e-08 34.4 0.1 7.8 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDP43736.1 - 7.4e-15 55.0 1.0 1.2e-12 47.8 0.1 3.3 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EDP43736.1 - 5.7e-07 29.8 2.3 0.0025 18.2 0.5 3.5 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EDP43736.1 - 6.9e-07 28.8 1.2 0.38 10.9 0.1 3.8 3 0 0 3 3 3 3 HEAT repeat Beta_elim_lyase PF01212.16 EDP43737.1 - 1.7e-29 102.9 0.5 2.1e-29 102.6 0.3 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDP43737.1 - 0.0039 16.2 0.1 0.0067 15.5 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EDP43737.1 - 0.035 12.3 0.1 0.045 12.0 0.1 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme NAD_binding_4 PF07993.7 EDP43738.1 - 0.014 14.2 0.0 0.038 12.9 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Syja_N PF02383.13 EDP43739.1 - 2e-87 292.9 0.0 2.5e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain U6-snRNA_bdg PF10596.4 EDP43739.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 U6-snRNA interacting domain of PrP8 WD40 PF00400.27 EDP43740.1 - 1e-35 120.3 8.8 9.4e-06 25.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.6 EDP43740.1 - 3.2e-27 94.0 1.2 1e-26 92.4 0.3 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like Nup160 PF11715.3 EDP43740.1 - 0.019 13.1 0.0 0.036 12.2 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EDP43740.1 - 0.021 13.1 0.0 0.047 11.9 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain FtsZ_C PF12327.3 EDP43740.1 - 0.1 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 FtsZ family, C-terminal domain IGPS PF00218.16 EDP43741.1 - 1.4e-90 302.7 0.7 9.9e-89 296.7 0.1 2.7 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EDP43741.1 - 2e-46 158.0 0.0 6.6e-42 143.3 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EDP43741.1 - 8.7e-44 149.2 0.1 5.6e-43 146.6 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDP43741.1 - 3.2e-06 26.7 2.7 6.4e-06 25.7 0.4 2.5 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 EDP43741.1 - 0.0086 15.6 0.1 0.048 13.1 0.1 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 EDP43741.1 - 0.0095 15.0 4.2 0.021 13.9 0.0 2.8 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG Actin PF00022.14 EDP43742.1 - 1.2e-06 27.2 0.0 1.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Actin PGM_PMM_I PF02878.11 EDP43743.1 - 1.2e-20 73.3 0.0 2.8e-09 36.6 0.0 3.1 2 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDP43743.1 - 7.8e-15 55.0 0.1 4.1e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDP43743.1 - 5.9e-10 39.0 0.1 1.7e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EDP43743.1 - 0.00045 20.2 0.2 0.0021 18.1 0.2 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PQ-loop PF04193.9 EDP43744.1 - 7.2e-11 41.4 0.9 1.1e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 PQ loop repeat MFS_1 PF07690.11 EDP43745.1 - 6.4e-18 64.5 22.3 1.2e-17 63.6 15.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP43745.1 - 8.3e-17 60.8 2.0 8.3e-17 60.8 1.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter JAB PF01398.16 EDP43746.1 - 1.5e-06 27.9 0.0 3.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HCV_NS2 PF01538.13 EDP43746.1 - 0.04 13.3 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DUF2590 PF10761.4 EDP43746.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) DUF1308 PF07000.6 EDP43747.1 - 0.029 13.0 0.6 0.067 11.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Ssu72 PF04722.8 EDP43748.1 - 1.8e-70 236.2 0.0 2e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF507 PF04368.8 EDP43748.1 - 0.043 13.4 1.0 0.066 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) LAG1-DNAbind PF09271.6 EDP43749.1 - 1.5e-22 80.5 0.0 5.8e-21 75.4 0.0 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EDP43749.1 - 6.2e-20 71.5 0.0 1.6e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF501 PF04417.7 EDP43749.1 - 0.026 14.3 0.5 0.061 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Las1 PF04031.8 EDP43750.1 - 7.9e-44 149.0 0.3 1.5e-43 148.0 0.2 1.5 1 0 0 1 1 1 1 Las1-like Thioredoxin_4 PF13462.1 EDP43751.1 - 7.7e-08 32.5 0.0 7.6e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin SAICAR_synt PF01259.13 EDP43752.1 - 5.6e-79 264.7 0.0 7.1e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.18 EDP43753.1 - 1.9e-105 352.2 1.1 1.1e-104 349.7 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Bac_DnaA PF00308.13 EDP43753.1 - 0.083 12.5 2.6 0.36 10.4 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein HsbA PF12296.3 EDP43753.1 - 0.85 9.4 12.3 0.13 12.1 0.3 3.7 3 1 0 3 3 3 0 Hydrophobic surface binding protein A AAA_22 PF13401.1 EDP43753.1 - 5.8 7.0 8.6 8.4 6.5 0.0 4.2 4 1 0 4 4 4 0 AAA domain Baculo_PEP_C PF04513.7 EDP43753.1 - 5.9 6.7 20.8 0.13 12.0 3.9 4.4 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 EDP43754.1 - 1.7e-64 211.5 18.1 1.6e-11 43.5 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDP43754.1 - 6.1e-05 21.3 7.5 0.25 9.4 1.5 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP43754.1 - 0.051 12.3 0.2 0.1 11.3 0.1 1.5 1 1 0 1 1 1 0 Nup133 N terminal like RNA_pol_Rpb4 PF03874.11 EDP43755.1 - 3.4e-15 56.0 0.2 4.7e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1018 PF06252.7 EDP43755.1 - 0.016 15.6 0.2 0.032 14.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Rhomboid PF01694.17 EDP43756.1 - 1.5e-10 41.2 0.7 4.3e-10 39.8 0.2 2.0 2 0 0 2 2 2 1 Rhomboid family Aminotran_1_2 PF00155.16 EDP43757.1 - 3e-49 167.9 0.0 9e-49 166.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDP43757.1 - 2e-05 23.0 0.0 7.9e-05 21.1 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EDP43757.1 - 0.0025 17.0 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDP43757.1 - 0.013 14.2 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_3 PF00202.16 EDP43757.1 - 0.081 11.7 0.3 0.15 10.8 0.2 1.4 1 0 0 1 1 1 0 Aminotransferase class-III PXB PF12828.2 EDP43758.1 - 6.1e-19 68.0 0.4 1.1e-17 63.8 0.0 3.0 2 1 0 2 2 2 1 PX-associated DUF3818 PF12825.2 EDP43758.1 - 9e-19 67.3 0.0 9e-19 67.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) CAF-1_p150 PF11600.3 EDP43758.1 - 0.11 11.8 28.5 0.17 11.2 19.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_13 PF13166.1 EDP43758.1 - 0.28 9.6 12.9 0.48 8.8 8.9 1.3 1 0 0 1 1 1 0 AAA domain CpXC PF14353.1 EDP43758.1 - 0.5 10.3 0.0 0.5 10.3 0.0 3.1 3 1 1 4 4 4 0 CpXC protein LMBR1 PF04791.11 EDP43758.1 - 1.2 7.5 4.7 1.9 7.0 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Asp-B-Hydro_N PF05279.6 EDP43758.1 - 3.1 7.5 15.7 7.1 6.4 10.9 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2433 PF10360.4 EDP43759.1 - 7.1e-28 97.5 0.0 1.2e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.17 EDP43759.1 - 0.0037 16.8 0.1 0.016 14.8 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 EDP43759.1 - 0.0047 16.7 0.0 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_6 PF14259.1 EDP43759.1 - 0.017 15.0 0.1 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EDP43759.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GTP_EFTU PF00009.22 EDP43760.1 - 8e-32 110.1 0.0 3.9e-31 107.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDP43760.1 - 1.6e-16 60.1 0.0 4.3e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDP43760.1 - 1.6e-13 50.5 3.5 1.2e-10 41.3 0.2 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP43760.1 - 1.3e-05 25.1 0.0 3.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EDP43760.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EDP43760.1 - 0.0011 19.4 0.0 0.0044 17.5 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EDP43760.1 - 0.021 14.9 0.1 0.093 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EDP43760.1 - 0.066 12.6 0.0 0.22 10.8 0.0 1.9 1 1 0 1 1 1 0 Ras family CPSase_L_D2 PF02786.12 EDP43761.1 - 3.5e-104 346.6 0.0 1.4e-81 272.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EDP43761.1 - 2.6e-40 137.0 0.3 5.3e-40 135.9 0.0 1.7 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EDP43761.1 - 5.2e-36 124.1 0.1 4e-17 62.5 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EDP43761.1 - 1.2e-31 109.0 0.0 8e-15 54.9 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EDP43761.1 - 6e-27 94.2 0.0 1.5e-10 40.3 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDP43761.1 - 4.1e-18 65.3 0.0 4.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDP43761.1 - 1.3e-12 47.4 0.0 7.2e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EDP43761.1 - 5e-08 32.6 0.0 0.00054 19.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EDP43761.1 - 1.5e-06 28.1 0.0 0.00037 20.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EDP43761.1 - 1.9e-05 23.9 0.3 0.036 13.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EDP43761.1 - 0.0026 17.3 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.17 EDP43761.1 - 0.014 15.3 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain Epimerase PF01370.16 EDP43761.1 - 0.022 14.1 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_M17_N PF02789.12 EDP43761.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Abhydrolase_6 PF12697.2 EDP43762.1 - 1.7e-12 47.7 4.2 3.1e-12 46.8 2.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EDP43762.1 - 8.2e-12 44.3 0.0 1.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EDP43762.1 - 4.4e-09 36.2 0.0 8.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP43762.1 - 1.9e-06 27.6 1.6 1.6e-05 24.6 1.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDP43762.1 - 0.11 12.3 0.2 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Putative lysophospholipase ATP-synt_S1 PF05827.7 EDP43763.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MAM33 PF02330.11 EDP43764.1 - 6.6e-35 120.7 0.0 7.7e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Thioredoxin PF00085.15 EDP43765.1 - 7.5e-34 115.5 0.0 2.9e-18 65.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EDP43765.1 - 2.9e-10 40.2 0.0 1.8e-07 31.1 0.0 3.1 2 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDP43765.1 - 7.7e-07 29.1 0.2 0.0031 17.5 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_4 PF13462.1 EDP43765.1 - 1.9e-05 24.7 0.6 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EDP43765.1 - 5.6e-05 23.2 0.4 0.74 10.0 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDP43765.1 - 0.00028 20.6 0.4 0.0095 15.7 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_7 PF13899.1 EDP43765.1 - 0.0023 17.9 0.3 1.3 9.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.8 EDP43765.1 - 0.15 11.9 0.1 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 ERp29, N-terminal domain RICTOR_M PF14666.1 EDP43766.1 - 4.5e-60 202.4 0.3 1.7e-59 200.5 0.0 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 EDP43766.1 - 1.3e-47 162.1 14.0 3.6e-47 160.7 2.7 3.2 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.1 EDP43766.1 - 6.3e-19 67.6 0.9 2.2e-17 62.7 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 EDP43766.1 - 1.2e-09 38.1 0.0 6.6e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HR1 PF02185.11 EDP43766.1 - 0.00017 21.2 0.3 0.0005 19.7 0.2 1.7 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EDP43766.1 - 3.8 7.4 7.6 2.1 8.3 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Coa1 PF08695.5 EDP43767.1 - 3.2e-34 116.9 0.0 4.1e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_S16 PF00886.14 EDP43769.1 - 8.6e-28 95.8 0.2 1.3e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Med26 PF08711.6 EDP43770.1 - 0.0058 16.1 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Methyltransf_28 PF02636.12 EDP43771.1 - 1.3e-32 113.2 0.0 2.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EDP43771.1 - 0.0036 17.7 0.1 0.022 15.2 0.0 2.4 4 0 0 4 4 4 1 Methyltransferase domain MMgT PF10270.4 EDP43772.1 - 3.9e-16 59.4 0.0 4.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Actin PF00022.14 EDP43773.1 - 1.9e-159 530.3 0.0 2.1e-159 530.1 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 EDP43773.1 - 0.0037 15.6 0.0 0.0053 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 EDP43773.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Nop PF01798.13 EDP43774.1 - 1.6e-59 199.4 0.0 3.7e-59 198.3 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDP43774.1 - 2.8e-26 91.0 0.1 6e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDP43774.1 - 1.4e-20 73.1 0.1 1.4e-20 73.1 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain CENP-T PF15511.1 EDP43774.1 - 0.017 14.4 13.4 0.024 13.8 9.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EDP43774.1 - 0.54 8.2 25.1 0.82 7.6 17.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Proteasome PF00227.21 EDP43775.1 - 9.5e-50 168.5 0.3 2.3e-47 160.7 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EDP43775.1 - 2.9e-15 55.2 0.1 4.9e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPR_11 PF13414.1 EDP43776.1 - 1e-16 60.3 33.5 5.3e-05 22.7 0.0 8.5 6 2 2 8 8 8 5 TPR repeat TPR_2 PF07719.12 EDP43776.1 - 3.8e-08 32.6 42.4 0.013 15.4 0.0 11.3 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43776.1 - 0.00017 21.8 39.0 1.1 9.6 0.2 10.8 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43776.1 - 0.0009 19.2 18.1 16 6.0 0.0 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43776.1 - 0.0014 19.0 3.7 0.0014 19.0 2.6 14.9 15 3 3 18 18 18 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43776.1 - 0.0019 18.5 0.7 0.0019 18.5 0.5 8.9 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP43776.1 - 0.0027 17.2 23.8 3 7.5 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDP43776.1 - 0.0029 17.2 4.0 3 7.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43776.1 - 0.0035 17.9 15.6 0.0069 17.0 2.6 11.6 13 3 1 14 14 14 4 Tetratricopeptide repeat Apc3 PF12895.2 EDP43776.1 - 0.46 10.6 18.1 0.54 10.4 0.0 5.5 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 SNO PF01174.14 EDP43777.1 - 6.1e-49 166.2 0.0 9.9e-39 132.9 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDP43777.1 - 1.7e-09 37.4 0.2 2.5e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 EDP43777.1 - 0.0005 19.5 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EDP43777.1 - 0.00053 19.7 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 EDP43777.1 - 0.0017 17.8 0.2 0.011 15.1 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I BPL_N PF09825.4 EDP43777.1 - 0.019 13.7 0.0 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Peptidase_C26 PF07722.8 EDP43777.1 - 0.14 11.5 0.1 0.49 9.8 0.1 1.9 1 1 0 1 1 1 0 Peptidase C26 MT-A70 PF05063.9 EDP43778.1 - 2.2e-16 59.9 0.0 3.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EDP43778.1 - 0.021 14.8 0.1 0.034 14.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.19 EDP43779.1 - 4.4e-135 451.0 9.0 5.1e-135 450.8 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAGLU_C PF12972.2 EDP43779.1 - 0.21 10.9 0.3 0.62 9.3 0.1 1.8 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain COX4 PF02936.9 EDP43780.1 - 2.2e-33 114.9 0.2 4.1e-33 114.1 0.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 EDP43780.1 - 0.45 10.0 1.6 12 5.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cys_Met_Meta_PP PF01053.15 EDP43781.1 - 3e-150 499.8 0.0 3.4e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDP43781.1 - 1.8e-12 46.8 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDP43781.1 - 3.4e-11 42.8 0.0 8.6e-11 41.4 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EDP43781.1 - 7e-08 31.5 0.1 1.5e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDP43781.1 - 6.2e-05 22.2 0.0 0.00011 21.4 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Radical_SAM PF04055.16 EDP43781.1 - 0.01 16.0 0.0 0.95 9.6 0.0 2.3 2 0 0 2 2 2 0 Radical SAM superfamily GDC-P PF02347.11 EDP43781.1 - 0.052 12.2 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein AP_endonuc_2 PF01261.19 EDP43781.1 - 0.076 12.2 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Met_gamma_lyase PF06838.6 EDP43781.1 - 0.083 11.1 0.1 0.19 9.9 0.1 1.6 1 1 0 1 1 1 0 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.15 EDP43782.1 - 2.1e-117 391.7 0.0 3.1e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EDP43782.1 - 3.9e-17 62.0 0.3 1.6e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDP43782.1 - 9e-06 25.8 0.1 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EDP43782.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature RTC PF01137.16 EDP43783.1 - 5.1e-59 198.8 0.0 6.3e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EDP43783.1 - 4.2e-29 100.5 0.0 7.4e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF2347 PF09804.4 EDP43784.1 - 2.1e-36 125.6 0.0 7.8e-35 120.5 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EDP43784.1 - 0.0026 16.3 0.1 1.7 7.0 0.0 2.4 2 1 0 2 2 2 2 Transport protein Avl9 Afi1 PF07792.7 EDP43784.1 - 0.044 13.7 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EDP43784.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis Prp19_bind PF06991.6 EDP43785.1 - 5.8e-51 173.3 12.4 5.8e-51 173.3 8.6 1.7 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain DUF1423 PF07227.6 EDP43785.1 - 0.16 10.5 3.1 0.21 10.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Arf PF00025.16 EDP43786.1 - 1.7e-52 177.1 0.0 6e-51 172.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDP43786.1 - 4.5e-10 38.7 0.0 6e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EDP43786.1 - 5.8e-07 30.0 0.0 7.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EDP43786.1 - 8.6e-07 28.3 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDP43786.1 - 3.6e-06 26.4 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EDP43786.1 - 2.8e-05 23.3 0.0 3.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SNF2_N PF00176.18 EDP43787.1 - 1.3e-69 234.2 0.1 2.5e-69 233.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP43787.1 - 9.9e-16 57.3 0.3 2.8e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 EDP43787.1 - 1.4e-07 31.2 5.0 1.4e-07 31.2 3.5 2.8 3 0 0 3 3 3 1 HSA DEAD PF00270.24 EDP43787.1 - 2.5e-05 23.8 0.0 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ATP-synt_Eps PF04627.8 EDP43788.1 - 6.3e-22 76.8 4.5 7.5e-22 76.6 3.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Bclt PF15318.1 EDP43788.1 - 0.028 14.4 0.1 0.028 14.4 0.1 1.1 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis PRRSV_Env PF02340.10 EDP43788.1 - 0.046 12.8 0.1 0.052 12.7 0.0 1.0 1 0 0 1 1 1 0 PRRSV putative envelope protein GPP34 PF05719.6 EDP43788.1 - 0.1 12.6 0.2 0.1 12.6 0.1 1.0 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF423 PF04241.10 EDP43789.1 - 1.2e-07 31.5 1.0 0.00043 20.1 0.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF423) SHIPPO-rpt PF07004.7 EDP43790.1 - 2.2e-16 59.8 119.6 31 5.7 0.2 31.5 6 3 4 10 10 10 1 Sperm-tail PG-rich repeat Nucleoporin_FG PF13634.1 EDP43790.1 - 1.5e-15 57.3 225.5 0.00013 22.1 11.5 10.1 3 1 8 11 11 11 8 Nucleoporin FG repeat region RabGAP-TBC PF00566.13 EDP43791.1 - 3.1e-24 85.6 0.8 4.4e-23 81.8 0.1 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain CDC50 PF03381.10 EDP43792.1 - 4.5e-86 288.4 0.0 5.8e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1049 PF06305.6 EDP43792.1 - 0.72 9.3 3.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) GTP_EFTU PF00009.22 EDP43793.1 - 2.1e-26 92.4 0.0 9e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDP43793.1 - 2.9e-09 37.0 0.0 7.6e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDP43793.1 - 6.6e-08 32.5 0.2 2.4e-07 30.7 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDP43793.1 - 0.00027 20.5 0.7 0.0022 17.5 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 4 MR_MLE_N PF02746.11 EDP43793.1 - 0.013 15.4 0.6 0.036 14.0 0.1 2.0 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PduV-EutP PF10662.4 EDP43793.1 - 0.015 14.7 0.3 12 5.3 0.0 3.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EDP43793.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 EDP43793.1 - 0.056 12.6 0.8 12 5.1 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family FeoB_N PF02421.13 EDP43793.1 - 0.1 11.8 0.2 3.9 6.7 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Y_phosphatase2 PF03162.8 EDP43794.1 - 3.3e-16 59.0 0.1 5e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Oxysterol_BP PF01237.13 EDP43795.1 - 4.4e-71 239.2 0.0 5.3e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein TPR_1 PF00515.23 EDP43796.1 - 1.4e-46 154.2 17.3 0.00013 21.3 0.2 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EDP43796.1 - 4.7e-43 144.6 15.2 4.6e-10 38.9 0.0 6.5 2 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 EDP43796.1 - 1.3e-40 134.0 14.9 0.00035 20.2 0.1 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EDP43796.1 - 1e-32 109.3 13.1 0.0002 20.9 0.0 9.9 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDP43796.1 - 1.6e-29 99.6 2.8 0.0021 18.5 0.0 9.7 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EDP43796.1 - 9.2e-24 83.1 15.9 0.00011 22.0 0.2 6.8 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 EDP43796.1 - 2.9e-23 81.9 7.4 0.00039 21.0 0.1 6.9 5 3 4 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 EDP43796.1 - 1.5e-21 74.4 11.4 0.11 12.3 0.0 9.4 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDP43796.1 - 2.5e-21 75.7 8.5 1.2e-05 25.5 0.0 7.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDP43796.1 - 9.3e-20 69.6 4.5 0.3 11.6 0.0 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDP43796.1 - 1.2e-18 65.6 9.3 0.02 15.0 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDP43796.1 - 1e-15 57.3 9.2 0.0066 16.2 0.0 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EDP43796.1 - 1.1e-11 44.6 3.8 0.00036 20.6 0.1 4.2 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EDP43796.1 - 7.7e-09 35.0 6.5 0.01 14.9 0.0 4.9 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.4 EDP43796.1 - 0.0069 16.3 6.2 4.7 7.1 0.0 4.4 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EDP43796.1 - 0.028 14.5 0.0 2.3 8.3 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EDP43796.1 - 0.13 11.0 0.2 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EDP43796.1 - 1.5 8.8 11.5 40 4.3 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat MIT PF04212.13 EDP43796.1 - 4.5 7.2 9.7 24 4.9 0.0 5.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain SNAP PF14938.1 EDP43796.1 - 9.6 5.2 6.9 22 4.0 0.1 3.7 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP SOR_SNZ PF01680.12 EDP43797.1 - 3.4e-116 386.1 4.4 6.1e-116 385.3 3.1 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EDP43797.1 - 2.7e-06 26.6 7.9 4.1e-05 22.7 0.5 2.5 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EDP43797.1 - 0.017 14.4 0.5 0.24 10.6 0.1 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein Trp_syntA PF00290.15 EDP43797.1 - 0.02 13.4 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain NanE PF04131.9 EDP43797.1 - 0.024 13.5 0.4 0.13 11.2 0.0 2.2 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EDP43797.1 - 0.035 13.2 0.2 0.035 13.2 0.1 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 EDP43797.1 - 0.038 13.0 0.9 0.17 10.9 0.0 2.3 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase Dus PF01207.12 EDP43797.1 - 0.043 12.6 0.5 5.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Rieske PF00355.21 EDP43798.1 - 1.7e-17 62.7 0.0 2.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EDP43798.1 - 1.3e-15 57.3 2.0 2.7e-15 56.3 1.4 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region SPT16 PF08644.6 EDP43799.1 - 2.8e-52 176.5 1.9 7.4e-52 175.2 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 EDP43799.1 - 5.1e-20 71.2 0.0 1.6e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Snurportin1 PF11538.3 EDP43799.1 - 9.2 6.1 8.2 11 5.9 0.4 2.6 2 0 0 2 2 2 0 Snurportin1 Atg8 PF02991.11 EDP43800.1 - 2.3e-48 162.4 0.1 2.7e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EDP43800.1 - 4e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HEAT PF02985.17 EDP43801.1 - 6.7e-10 38.2 10.3 0.038 14.0 0.1 7.7 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EDP43801.1 - 3e-07 30.6 0.1 0.043 14.1 0.0 5.3 3 2 1 4 4 4 1 HEAT repeats BSP_II PF05432.6 EDP43801.1 - 0.057 12.7 10.5 0.093 11.9 7.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Voldacs PF03517.8 EDP43801.1 - 1.9 8.3 9.5 1.1 9.1 4.4 2.0 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling OPT PF03169.10 EDP43802.1 - 1.1e-132 443.5 48.6 1.3e-132 443.3 33.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PDEase_II PF02112.10 EDP43803.1 - 1.4e-29 103.1 0.0 3e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Glu_synthase PF01645.12 EDP43804.1 - 8.5e-160 531.6 0.0 1.4e-159 530.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EDP43804.1 - 1.3e-128 428.7 0.0 1.9e-128 428.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EDP43804.1 - 2.9e-109 364.7 0.0 5.3e-109 363.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EDP43804.1 - 4e-66 221.8 1.2 7.5e-66 220.9 0.8 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EDP43804.1 - 9.8e-23 79.9 0.1 2.7e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EDP43804.1 - 4.5e-18 65.8 0.0 1.8e-17 63.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP43804.1 - 4.7e-11 43.1 0.1 0.00022 21.3 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP43804.1 - 1.3e-08 34.7 0.0 5.6e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDP43804.1 - 4.7e-07 30.1 4.3 4.6e-05 23.7 0.1 3.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDP43804.1 - 3.1e-06 26.5 0.1 5.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EDP43804.1 - 2.6e-05 23.2 2.6 9.7e-05 21.4 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDP43804.1 - 3.7e-05 22.3 0.1 3.7e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EDP43804.1 - 9.1e-05 21.4 0.8 0.0002 20.3 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain AdoHcyase_NAD PF00670.16 EDP43804.1 - 0.00018 21.4 0.9 0.71 9.6 0.2 2.7 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 EDP43804.1 - 0.00026 21.2 0.1 0.82 9.9 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 EDP43804.1 - 0.00026 20.2 0.2 0.00053 19.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EDP43804.1 - 0.0015 17.7 0.1 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EDP43804.1 - 0.0022 17.7 0.1 0.0069 16.1 0.0 1.9 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EDP43804.1 - 0.0028 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EDP43804.1 - 0.017 14.7 0.3 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDP43804.1 - 0.082 12.0 0.0 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 EDP43804.1 - 0.13 10.4 0.4 1.5 6.9 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.17 EDP43804.1 - 0.26 10.1 4.5 0.055 12.3 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EDP43804.1 - 0.26 11.3 0.7 9.8 6.2 0.1 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDP43804.1 - 0.83 9.2 5.0 0.1 12.2 0.1 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Prp31_C PF09785.4 EDP43806.1 - 1.1e-39 135.7 2.6 1.1e-39 135.7 1.8 1.5 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EDP43806.1 - 1.9e-30 105.1 0.2 3.6e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Adenylsucc_synt PF00709.16 EDP43807.1 - 1.8e-157 524.3 0.0 2e-157 524.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CybS PF05328.7 EDP43808.1 - 7e-37 126.0 0.2 8.2e-34 116.0 0.0 2.2 2 0 0 2 2 2 2 CybS TFIIS_C PF01096.13 EDP43809.1 - 2.4e-09 36.6 3.1 2.4e-09 36.6 2.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EDP43809.1 - 0.0032 17.7 0.8 0.0043 17.3 0.6 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar T4_baseplate PF12322.3 EDP43809.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein CpXC PF14353.1 EDP43809.1 - 0.17 11.8 3.7 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 CpXC protein zf-C2H2_4 PF13894.1 EDP43809.1 - 0.23 11.8 4.1 0.98 9.9 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.8 EDP43809.1 - 0.24 10.9 3.1 0.48 9.9 2.2 1.6 1 1 0 1 1 1 0 InsA N-terminal domain Zn-ribbon_8 PF09723.5 EDP43809.1 - 0.27 11.1 4.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain E1_dh PF00676.15 EDP43810.1 - 7.9e-110 366.2 0.0 9e-110 366.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDP43810.1 - 0.0024 16.8 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 EDP43810.1 - 0.033 13.0 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Pribosyltran PF00156.22 EDP43811.1 - 4.9e-08 32.7 0.1 4.9e-08 32.7 0.1 2.0 2 1 0 2 2 2 1 Phosphoribosyl transferase domain DUF962 PF06127.6 EDP43812.1 - 7.7e-22 77.0 1.6 3e-21 75.1 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Calici_coat_C PF08435.6 EDP43812.1 - 0.021 14.1 0.7 0.039 13.2 0.5 1.4 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF974 PF06159.8 EDP43813.1 - 4.5e-30 104.9 0.0 5.8e-29 101.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF974) DUF2454 PF10521.4 EDP43814.1 - 1.1e-07 31.1 0.1 4.6e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2454) zf-C3HC4_3 PF13920.1 EDP43815.1 - 5.1e-05 22.8 6.5 5.1e-05 22.8 4.5 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EDP43815.1 - 1.3 9.5 29.9 0.69 10.3 1.8 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type Methyltransf_26 PF13659.1 EDP43816.1 - 5.4e-11 42.5 0.0 1.5e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EDP43816.1 - 1.7e-10 40.7 0.0 5.8e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EDP43816.1 - 0.013 15.0 0.1 0.72 9.2 0.0 2.5 2 1 0 2 2 2 0 DNA methylase N6_Mtase PF02384.11 EDP43816.1 - 0.1 11.6 0.0 0.56 9.2 0.0 1.9 1 1 0 1 1 1 0 N-6 DNA Methylase DNA_ligase_A_M PF01068.16 EDP43817.1 - 4.7e-13 48.9 0.0 6.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Mito_carr PF00153.22 EDP43818.1 - 8.9e-05 22.1 0.3 0.011 15.3 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein V-ATPase_H_N PF03224.9 EDP43819.1 - 1.5e-55 188.5 0.8 3.2e-54 184.1 0.1 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EDP43819.1 - 1.7e-32 111.8 0.6 4.9e-32 110.3 0.2 1.9 2 0 0 2 2 2 1 V-ATPase subunit H MMS22L_C PF14911.1 EDP43819.1 - 0.015 14.3 0.1 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal RIX1 PF08167.7 EDP43819.1 - 0.024 14.2 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.1 EDP43819.1 - 0.074 13.3 0.6 4.2 7.7 0.0 3.2 2 2 0 2 2 2 0 HEAT repeats VHS PF00790.14 EDP43819.1 - 0.087 12.4 0.4 0.96 9.0 0.0 2.5 2 0 0 2 2 2 0 VHS domain MRP-L46 PF11788.3 EDP43820.1 - 2.5e-16 60.3 0.1 4.6e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 CBS PF00571.23 EDP43821.1 - 7.3e-19 67.2 2.7 2.9e-06 26.9 0.0 5.4 5 0 0 5 5 5 5 CBS domain Ubiq_cyt_C_chap PF03981.7 EDP43822.1 - 1.4e-29 102.7 0.0 3.8e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone His_biosynth PF00977.16 EDP43823.1 - 2.7e-14 52.9 0.0 3.9e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Nic96 PF04097.9 EDP43824.1 - 4.1e-151 504.1 0.3 5.8e-151 503.6 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF4364 PF14277.1 EDP43824.1 - 0.03 13.9 0.4 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Pkinase PF00069.20 EDP43825.1 - 6.7e-41 140.1 0.4 5.4e-23 81.4 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43825.1 - 4.7e-11 42.2 0.2 2.9e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDP43825.1 - 0.069 11.9 0.1 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NOA36 PF06524.7 EDP43825.1 - 2.4 7.3 3.7 3.8 6.6 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein Rsa3 PF14615.1 EDP43826.1 - 6.7e-06 25.3 0.8 0.00061 19.0 0.1 2.2 2 0 0 2 2 2 2 Ribosome-assembly protein 3 plasmid_Toxin PF12703.2 EDP43826.1 - 0.059 13.1 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system DUF2217 PF10265.4 EDP43826.1 - 1.1 7.8 8.3 1.3 7.6 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) NOA36 PF06524.7 EDP43826.1 - 7.3 5.7 8.9 12 5.0 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein Glucosamine_iso PF01182.15 EDP43827.1 - 5.2e-28 98.1 0.0 6.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF2617 PF10936.3 EDP43827.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF2617 tRNA-synt_2b PF00587.20 EDP43828.1 - 5.9e-42 143.1 0.0 9.7e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDP43828.1 - 1e-07 31.7 0.0 9.1e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Anticodon binding domain Nse4_C PF08743.5 EDP43829.1 - 2.1e-16 59.7 0.0 4.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EDP43829.1 - 2.7e-11 43.1 0.3 5.7e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Sec15 PF04091.7 EDP43830.1 - 1.5e-83 280.6 4.8 1.5e-83 280.6 3.4 2.9 3 1 1 4 4 4 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 EDP43830.1 - 1e-06 28.4 9.1 1e-06 28.4 6.3 3.0 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 EDP43830.1 - 3.9e-06 26.7 3.0 3.9e-06 26.7 2.1 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EDP43830.1 - 0.00037 20.2 3.2 0.00041 20.1 0.4 2.6 2 1 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EDP43830.1 - 0.00066 19.5 12.9 0.008 16.0 4.7 3.3 3 0 0 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 EDP43830.1 - 0.0021 18.0 2.9 0.011 15.7 1.6 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 NOP5NT PF08156.8 EDP43830.1 - 0.069 13.3 0.2 4.2 7.5 0.1 3.3 2 0 0 2 2 2 0 NOP5NT (NUC127) domain DEAD PF00270.24 EDP43831.1 - 2.1e-41 141.2 0.0 2.3e-40 137.8 0.0 2.6 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43831.1 - 8.7e-25 86.3 0.1 1.1e-23 82.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EDP43831.1 - 0.0035 17.3 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EDP43831.1 - 0.007 14.8 0.0 0.15 10.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EDP43831.1 - 0.024 14.4 0.0 0.14 12.0 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit zf-CCHC_4 PF14392.1 EDP43831.1 - 0.11 12.1 1.1 0.23 11.1 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2608 PF11019.3 EDP43831.1 - 0.15 11.0 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF2285 PF10074.4 EDP43831.1 - 0.26 11.6 5.6 0.18 12.1 1.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Arf PF00025.16 EDP43832.1 - 4.7e-74 247.3 0.0 5.6e-74 247.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDP43832.1 - 1.1e-12 47.5 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDP43832.1 - 1e-11 44.5 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDP43832.1 - 2.3e-10 39.7 0.5 7.9e-07 28.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDP43832.1 - 7.5e-10 38.3 0.0 8.9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDP43832.1 - 9.5e-07 29.3 0.0 1.3e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP43832.1 - 3.2e-06 27.0 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDP43832.1 - 0.025 14.0 0.0 0.22 10.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EDP43832.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 EDP43832.1 - 0.15 11.2 0.1 0.23 10.7 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B CAP_GLY PF01302.20 EDP43833.1 - 7.7e-23 79.9 0.2 1.2e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Dynactin PF12455.3 EDP43833.1 - 5.6e-14 51.7 3.4 5.6e-14 51.7 2.3 3.6 3 1 0 4 4 4 1 Dynein associated protein IncA PF04156.9 EDP43833.1 - 0.00021 20.9 56.4 0.0052 16.4 8.5 4.2 3 1 0 3 3 3 3 IncA protein Mnd1 PF03962.10 EDP43833.1 - 0.072 12.7 46.0 0.2 11.2 8.6 4.6 2 1 2 4 4 4 0 Mnd1 family ATG16 PF08614.6 EDP43833.1 - 0.34 10.6 58.6 0.012 15.4 7.7 4.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EDP43833.1 - 5.3 5.3 31.5 1.2 7.5 4.1 3.1 2 1 1 3 3 3 0 AAA domain Bacillus_HBL PF05791.6 EDP43833.1 - 7.1 5.9 19.7 0.067 12.5 0.2 4.3 3 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 EDP43833.1 - 9.7 5.3 46.3 0.8 8.8 9.1 4.4 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Lon_C PF05362.8 EDP43834.1 - 6.1e-63 211.8 0.2 1.2e-62 210.8 0.0 1.6 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EDP43834.1 - 9.6e-24 84.0 0.0 2.3e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP43834.1 - 2.6e-09 36.9 0.0 7.9e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EDP43834.1 - 2.9e-09 36.4 0.0 7.7e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EDP43834.1 - 1.1e-05 25.5 0.2 5.3e-05 23.2 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EDP43834.1 - 2.4e-05 23.4 0.0 0.02 13.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDP43834.1 - 3.5e-05 24.6 0.0 8.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP43834.1 - 9.9e-05 22.2 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP43834.1 - 0.00011 21.9 0.1 0.00036 20.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EDP43834.1 - 0.00017 21.6 0.0 0.0023 18.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EDP43834.1 - 0.0021 16.7 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain Zeta_toxin PF06414.7 EDP43834.1 - 0.0026 16.9 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EDP43834.1 - 0.0033 17.0 0.1 0.088 12.4 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDP43834.1 - 0.0069 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP43834.1 - 0.008 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDP43834.1 - 0.0098 15.0 0.1 0.055 12.6 0.1 2.2 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EDP43834.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EDP43834.1 - 0.012 14.3 0.1 0.1 11.3 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus RuvB_N PF05496.7 EDP43834.1 - 0.013 14.5 0.1 0.071 12.1 0.1 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDP43834.1 - 0.021 14.7 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EDP43834.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EDP43834.1 - 0.027 14.4 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EDP43834.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EDP43834.1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDP43834.1 - 0.046 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 1 0 PhoH-like protein CPT PF07931.7 EDP43834.1 - 0.063 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 EDP43834.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 EDP43834.1 - 0.077 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase KTI12 PF08433.5 EDP43834.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EDP43834.1 - 0.077 12.6 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EDP43834.1 - 0.086 12.5 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EDP43834.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EDP43834.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EDP43834.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EDP43834.1 - 0.22 11.7 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_1c PF00749.16 EDP43835.1 - 5.9e-87 291.2 0.0 7.7e-87 290.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1d PF00750.14 EDP43835.1 - 0.13 11.0 0.0 7.3 5.2 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class I (R) SynMuv_product PF06047.6 EDP43836.1 - 1.2e-47 160.0 3.4 1.4e-47 159.7 2.4 1.0 1 0 0 1 1 1 1 Ras-induced vulval development antagonist eIF-5_eIF-2B PF01873.12 EDP43837.1 - 1.4e-41 141.0 0.0 2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EDP43837.1 - 7.9e-26 89.8 0.1 7.9e-26 89.8 0.1 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DNA_RNApol_7kD PF03604.8 EDP43837.1 - 0.28 10.7 3.2 0.5 9.8 2.2 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Pox_Ag35 PF03286.9 EDP43837.1 - 5.9 6.3 15.0 13 5.2 6.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TRAPP PF04051.11 EDP43838.1 - 1e-26 93.3 0.0 1.2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pkinase PF00069.20 EDP43839.1 - 7.1e-44 149.9 0.0 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EDP43839.1 - 4e-43 146.3 0.3 7.5e-43 145.4 0.2 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EDP43839.1 - 1.1e-23 83.6 0.0 1.7e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EDP43839.1 - 1.7e-05 24.0 0.0 0.00018 20.8 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 EDP43839.1 - 1.9e-05 24.2 0.0 0.00056 19.4 0.0 2.8 1 1 1 2 2 2 1 PQQ-like domain ArsA_ATPase PF02374.10 EDP43840.1 - 6e-106 353.9 0.0 6.9e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EDP43840.1 - 1.7e-14 53.6 0.0 3.1e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDP43840.1 - 9e-09 35.4 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EDP43840.1 - 3.9e-06 26.2 0.2 3.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EDP43840.1 - 0.0003 20.3 0.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EDP43840.1 - 0.0012 18.3 0.2 0.014 14.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 EDP43840.1 - 0.0038 16.4 0.0 0.0085 15.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein YhjQ PF06564.7 EDP43840.1 - 0.0041 16.5 0.0 0.0079 15.5 0.0 1.4 2 0 0 2 2 2 1 YhjQ protein MipZ PF09140.6 EDP43840.1 - 0.0045 16.1 0.1 0.021 13.9 0.0 2.1 2 1 0 2 2 2 1 ATPase MipZ AAA_19 PF13245.1 EDP43840.1 - 0.01 15.5 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 EDP43840.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CTP_synth_N PF06418.9 EDP43840.1 - 0.059 12.4 0.1 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 CTP synthase N-terminus AAA_24 PF13479.1 EDP43840.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDP43840.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Acetyltransf_1 PF00583.19 EDP43841.1 - 8.9e-13 48.0 0.1 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDP43841.1 - 4.4e-06 26.7 0.0 9.7e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDP43841.1 - 4.5e-06 26.3 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EDP43841.1 - 0.00069 19.4 0.3 0.0014 18.4 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDP43841.1 - 0.0019 18.0 0.2 0.0022 17.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDP43841.1 - 0.005 16.9 0.0 0.0069 16.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Atg14 PF10186.4 EDP43842.1 - 2.5e-12 46.3 4.2 3.8e-12 45.7 2.9 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF1409 PF07197.7 EDP43842.1 - 1.7 8.7 6.2 2.2 8.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) CDC45 PF02724.9 EDP43843.1 - 4.4e-184 613.0 0.0 5e-184 612.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein NESP55 PF06390.7 EDP43843.1 - 0.007 15.7 4.9 0.013 14.9 3.4 1.4 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) SNF2_N PF00176.18 EDP43844.1 - 1.6e-79 266.8 0.5 2.6e-79 266.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 EDP43844.1 - 8.2e-15 54.3 7.2 8.2e-15 54.3 5.0 2.7 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EDP43844.1 - 7.7e-08 31.6 0.5 7.7e-08 31.6 0.4 2.5 2 0 0 2 2 2 1 QLQ ResIII PF04851.10 EDP43844.1 - 1.2e-05 25.2 0.4 5.2e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Bromodomain PF00439.20 EDP43845.1 - 9.3e-18 63.9 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EDP43845.1 - 2.1e-17 62.7 0.0 6.5e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.1 EDP43845.1 - 3.5e-13 49.5 5.4 3.5e-13 49.5 3.7 4.0 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Usp PF00582.21 EDP43846.1 - 4.9e-16 59.1 0.0 8.5e-16 58.4 0.0 1.3 1 1 0 1 1 1 1 Universal stress protein family Ribosomal_L3 PF00297.17 EDP43847.1 - 3.9e-121 403.4 5.9 4.5e-121 403.2 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 zf-HC5HC2H_2 PF13832.1 EDP43848.1 - 2.8e-19 69.1 7.8 2.8e-19 69.1 5.4 4.7 5 0 0 5 5 5 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDP43848.1 - 7.3e-17 61.3 6.9 7.3e-17 61.3 4.8 4.5 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 EDP43848.1 - 4.2e-16 58.3 50.5 8.5e-09 34.9 4.6 5.9 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 EDP43848.1 - 3.7e-13 49.2 0.0 7.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 EDP43848.1 - 1.6e-06 27.3 21.7 2.4e-06 26.7 0.6 4.9 4 0 0 4 4 4 2 PHD-finger GATA PF00320.22 EDP43848.1 - 0.0014 17.8 0.7 0.0014 17.8 0.5 4.0 4 0 0 4 4 4 2 GATA zinc finger ELM2 PF01448.19 EDP43848.1 - 0.0059 17.2 0.1 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 ELM2 domain Sugar_tr PF00083.19 EDP43850.1 - 1.4e-119 399.6 12.0 1.7e-119 399.3 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP43850.1 - 3.7e-25 88.4 37.3 1.5e-23 83.1 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 EDP43851.1 - 1.5e-33 114.2 0.0 3.9e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43851.1 - 2.8e-18 65.6 0.0 2.8e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43851.1 - 3.9e-17 61.8 0.0 5.6e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDP43851.1 - 0.029 14.1 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.5 EDP43851.1 - 0.14 12.1 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Per1 PF04080.8 EDP43852.1 - 7.9e-75 251.7 4.8 1.4e-74 250.9 3.3 1.3 1 0 0 1 1 1 1 Per1-like eIF3_subunit PF08597.5 EDP43853.1 - 3.4e-35 121.7 22.1 3.8e-35 121.6 15.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SR-25 PF10500.4 EDP43853.1 - 8.4 5.7 11.7 0.35 10.2 3.6 1.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Troponin-I_N PF11636.3 EDP43853.1 - 9.5 6.0 10.4 0.93 9.2 3.6 2.0 2 0 0 2 2 2 0 Troponin I residues 1-32 tRNA-synt_1 PF00133.17 EDP43854.1 - 1.5e-144 482.2 0.0 2e-144 481.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDP43854.1 - 7.5e-20 70.9 0.0 3.2e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDP43854.1 - 1.5e-19 70.2 0.0 2.6e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EDP43854.1 - 0.00027 20.4 3.3 0.00061 19.3 2.3 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EDP43854.1 - 0.0087 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Pox_MCEL PF03291.11 EDP43855.1 - 1.6e-67 227.7 0.0 2.1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EDP43855.1 - 3.5e-10 39.6 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP43855.1 - 3.8e-10 40.1 0.0 8.1e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP43855.1 - 2.5e-09 37.6 0.0 4.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP43855.1 - 4.1e-08 33.1 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP43855.1 - 1.4e-07 31.9 0.0 3.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP43855.1 - 4.3e-07 30.2 0.0 7.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP43855.1 - 6.3e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDP43855.1 - 0.00043 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 EDP43855.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Mak10 PF04112.8 EDP43856.1 - 8e-26 90.2 0.0 1.7e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PIG-U PF06728.8 EDP43857.1 - 6.3e-10 38.4 0.2 7.1e-10 38.2 0.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2418 PF10332.4 EDP43857.1 - 0.046 14.0 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) Mo25 PF08569.6 EDP43858.1 - 6.2e-91 304.9 1.9 6.8e-91 304.7 1.3 1.0 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.9 EDP43858.1 - 0.0024 17.0 0.1 0.0064 15.6 0.1 1.6 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 EDP43858.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Adaptin_N PF01602.15 EDP43859.1 - 5.7e-137 457.2 9.4 6.7e-137 456.9 6.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EDP43859.1 - 2.4e-13 50.4 0.0 4.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EDP43859.1 - 0.0025 17.7 1.0 20 5.5 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 EDP43859.1 - 0.019 14.5 0.3 0.019 14.5 0.2 3.3 3 2 1 4 4 4 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 EDP43859.1 - 0.023 14.5 10.2 0.021 14.6 1.1 3.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 EDP43859.1 - 0.032 13.9 2.2 0.73 9.4 0.1 3.6 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 EDP43859.1 - 0.37 10.7 2.9 5 7.0 0.1 3.3 3 1 1 4 4 4 0 V-ATPase subunit H MFS_1 PF07690.11 EDP43860.1 - 1.7e-12 46.7 20.5 1.7e-12 46.7 14.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 EDP43860.1 - 0.0032 15.5 7.4 0.15 10.0 0.2 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UPF1_Zn_bind PF09416.5 EDP43861.1 - 3e-66 221.7 1.9 3e-66 221.7 1.3 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EDP43861.1 - 9e-58 194.9 0.0 3.5e-57 193.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDP43861.1 - 2.4e-56 190.9 1.5 2.4e-56 190.9 1.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDP43861.1 - 1.7e-16 59.7 1.0 1.1e-13 50.7 0.2 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EDP43861.1 - 2.4e-14 53.3 0.2 5e-12 45.8 0.1 3.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EDP43861.1 - 5.9e-08 32.7 2.3 2.2e-07 30.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EDP43861.1 - 3.4e-06 26.5 4.8 0.026 13.8 0.1 3.4 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EDP43861.1 - 8.7e-06 25.4 0.2 3.3e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EDP43861.1 - 1.7e-05 24.4 0.5 0.46 9.9 0.0 3.4 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EDP43861.1 - 0.0002 20.8 0.0 0.029 13.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DEAD PF00270.24 EDP43861.1 - 0.00045 19.7 0.5 0.014 14.8 0.4 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EDP43861.1 - 0.00058 18.9 0.3 0.00058 18.9 0.2 3.1 4 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EDP43861.1 - 0.0013 17.6 0.1 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ABC_tran PF00005.22 EDP43861.1 - 0.0078 16.5 0.1 0.23 11.7 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EDP43861.1 - 0.013 15.6 0.3 0.44 10.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.1 EDP43861.1 - 0.016 15.2 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EDP43861.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 EDP43861.1 - 0.058 13.1 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDP43861.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDP43861.1 - 0.071 12.5 0.8 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EDP43861.1 - 0.12 11.4 0.0 0.41 9.7 0.0 1.9 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.9 EDP43861.1 - 0.14 11.8 0.8 0.68 9.6 0.1 2.4 2 1 1 3 3 3 0 Flavivirus DEAD domain AMP-binding PF00501.23 EDP43862.1 - 7.1e-70 235.4 0.0 8.2e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDP43862.1 - 1.5e-12 48.3 0.0 5.4e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.9 EDP43862.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MoCF_biosynth PF00994.19 EDP43864.1 - 5e-34 116.7 0.0 6.9e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF500 PF04366.7 EDP43865.1 - 1.6e-36 124.5 0.5 2.6e-36 123.8 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EDP43865.1 - 3.1e-10 39.2 0.1 5.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDP43865.1 - 2.9e-09 36.2 0.0 4.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EDP43865.1 - 5e-09 35.5 0.1 9.5e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.3 EDP43865.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Pkinase PF00069.20 EDP43866.1 - 4.5e-12 45.6 0.1 1.1e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RWD PF05773.17 EDP43866.1 - 1.8e-08 34.2 0.1 1.8e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 RWD domain DUF2570 PF10828.3 EDP43866.1 - 0.52 9.9 6.5 20 4.8 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF3682 PF12446.3 EDP43866.1 - 3.5 7.9 7.4 6.2 7.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Pkinase PF00069.20 EDP43867.1 - 2.1e-40 138.5 0.0 5.8e-40 137.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43867.1 - 1.1e-18 67.2 0.0 2.6e-18 66.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EDP43867.1 - 1.1e-18 67.3 0.0 3.4e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 EDP43867.1 - 2.9e-16 59.4 0.0 5.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 EDP43867.1 - 0.00068 19.4 2.4 0.0015 18.2 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP43867.1 - 0.0054 15.7 0.0 0.013 14.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Ank_2 PF12796.2 EDP43868.1 - 2.1e-15 56.8 0.0 3.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP43868.1 - 6.1e-14 52.0 0.2 1.7e-10 41.1 0.3 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP43868.1 - 8.7e-12 44.8 0.8 2.8e-07 30.5 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EDP43868.1 - 9.5e-11 40.9 0.5 9.7e-08 31.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EDP43868.1 - 4.6e-09 35.6 0.2 1.8e-05 24.5 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_18 PF12847.2 EDP43868.1 - 2.2e-05 24.9 0.1 0.0013 19.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Nucleoporin_FG PF13634.1 EDP43869.1 - 1e-32 112.7 196.4 3.4e-13 49.8 29.1 4.3 1 1 3 4 4 4 4 Nucleoporin FG repeat region Rab5-bind PF09311.6 EDP43869.1 - 0.057 13.3 9.8 0.099 12.5 6.8 1.3 1 0 0 1 1 1 0 Rabaptin-like protein DUF4559 PF15112.1 EDP43869.1 - 0.37 9.8 5.4 0.69 9.0 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Mnd1 PF03962.10 EDP43869.1 - 1.8 8.1 7.8 0.7 9.5 2.8 1.8 1 1 1 2 2 2 0 Mnd1 family TACC PF05010.9 EDP43869.1 - 3.6 7.3 7.6 3.5 7.3 3.2 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) ABC_tran PF00005.22 EDP43870.1 - 3.1e-31 108.4 0.0 4.6e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDP43870.1 - 7.9e-19 68.1 2.3 1.1e-18 67.6 1.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDP43870.1 - 0.0015 17.8 0.3 0.027 13.7 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP43870.1 - 0.0024 17.8 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDP43870.1 - 0.015 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDP43870.1 - 0.019 15.7 0.0 0.036 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDP43870.1 - 0.033 13.7 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDP43870.1 - 0.035 14.2 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDP43870.1 - 0.11 12.4 1.4 0.93 9.4 1.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EDP43870.1 - 0.12 11.8 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EDP43871.1 - 7.6e-28 97.5 0.0 9.7e-27 93.9 0.0 2.3 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDP43871.1 - 2.5e-24 86.1 10.6 2.5e-24 86.1 7.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EDP43871.1 - 8.8e-08 31.6 0.2 0.00045 19.5 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDP43871.1 - 0.00014 21.3 0.1 0.00033 20.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EDP43871.1 - 0.00014 21.9 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDP43871.1 - 0.00024 19.8 0.1 0.0017 17.0 0.0 2.2 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 EDP43871.1 - 0.00028 21.6 0.0 0.00076 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP43871.1 - 0.00035 20.3 0.0 0.022 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EDP43871.1 - 0.00058 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP43871.1 - 0.0031 17.8 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDP43871.1 - 0.0057 16.8 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP43871.1 - 0.0062 16.5 0.0 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EDP43871.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDP43871.1 - 0.011 15.1 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDP43871.1 - 0.082 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDP43871.1 - 0.089 12.6 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EDP43871.1 - 0.095 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EDP43871.1 - 0.21 11.0 1.3 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain DUF4383 PF14325.1 EDP43871.1 - 0.45 10.5 11.6 0.05 13.6 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) SNF2_N PF00176.18 EDP43872.1 - 5e-68 229.0 1.9 1.2e-67 227.7 1.3 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP43872.1 - 9.1e-16 57.4 0.0 2.3e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DZR PF12773.2 EDP43872.1 - 0.081 12.7 2.3 0.21 11.4 1.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon HHH PF00633.18 EDP43873.1 - 0.0013 18.2 0.1 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 EDP43873.1 - 0.0019 18.4 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GLE1 PF07817.8 EDP43874.1 - 4.2e-57 192.9 0.0 4.2e-57 192.9 0.0 1.7 2 1 0 2 2 2 1 GLE1-like protein MAP7 PF05672.6 EDP43874.1 - 0.00073 18.9 29.4 0.0016 17.8 20.4 1.5 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 EDP43874.1 - 0.022 14.1 21.4 0.036 13.4 14.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PmbA_TldD PF01523.11 EDP43874.1 - 0.12 11.6 5.0 0.2 10.9 3.5 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase He_PIG PF05345.7 EDP43875.1 - 9.1e-09 35.2 2.1 0.0058 16.6 0.1 4.8 6 0 0 6 6 6 2 Putative Ig domain TRAPP PF04051.11 EDP43876.1 - 5e-37 126.7 0.0 6.2e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component APH_6_hur PF04655.9 EDP43876.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Aldedh PF00171.17 EDP43877.1 - 2.8e-104 349.0 0.0 3.2e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOG1 PF06858.9 EDP43880.1 - 6.4e-29 99.6 0.1 1.2e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EDP43880.1 - 7.3e-29 99.2 3.5 1.8e-28 97.9 2.5 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EDP43880.1 - 6.2e-18 64.8 0.0 1.7e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP43880.1 - 4.3e-09 35.8 0.0 7.5e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EDP43880.1 - 1.5e-05 25.4 0.1 0.00012 22.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDP43880.1 - 5.8e-05 22.9 1.8 1.2 8.9 0.0 3.5 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EDP43880.1 - 0.003 16.7 0.0 0.032 13.3 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EDP43880.1 - 0.0052 15.9 0.3 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EDP43880.1 - 0.026 13.9 0.1 0.026 13.9 0.1 3.1 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDP43880.1 - 0.056 12.5 2.8 0.073 12.1 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Ras PF00071.17 EDP43880.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras family Abhydrolase_5 PF12695.2 EDP43881.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EDP43881.1 - 0.014 14.3 0.2 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 EDP43881.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 EDP43881.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF4532 PF15046.1 EDP43881.1 - 0.048 12.6 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Acetyltransf_1 PF00583.19 EDP43882.1 - 4.6e-06 26.5 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDP43882.1 - 0.019 15.0 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDP43882.1 - 0.02 15.0 0.0 0.038 14.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAN_3 PF08277.7 EDP43882.1 - 0.044 13.4 0.5 0.09 12.4 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain Acetyltransf_9 PF13527.1 EDP43882.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CRAL_TRIO PF00650.15 EDP43883.1 - 8.5e-34 116.3 0.1 1.4e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDP43883.1 - 4.8e-08 33.0 0.5 4.8e-08 33.0 0.4 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDP43883.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Ilar_coat PF01787.11 EDP43883.1 - 0.12 11.9 1.2 0.25 10.9 0.7 1.6 2 0 0 2 2 2 0 Ilarvirus coat protein zf-RING_2 PF13639.1 EDP43884.1 - 5.4e-16 58.1 1.3 1.3e-15 56.9 0.9 1.7 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EDP43884.1 - 4.7e-10 39.0 0.0 4e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EDP43884.1 - 1.8e-09 37.4 0.5 3.4e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP43884.1 - 3.8e-08 32.9 0.2 6.4e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDP43884.1 - 6.7e-08 32.5 0.2 2.3e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDP43884.1 - 2.8e-06 26.9 0.3 4.6e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP43884.1 - 7.1e-06 25.5 0.1 1.5e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDP43884.1 - 4.7e-05 23.0 0.4 0.0001 21.9 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDP43884.1 - 0.00015 21.4 0.7 0.00034 20.3 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EDP43884.1 - 0.0042 16.5 0.1 0.0088 15.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EDP43884.1 - 0.0052 16.3 1.3 0.0098 15.4 0.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EDP43884.1 - 0.011 15.6 3.6 0.03 14.2 1.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain Rtf2 PF04641.7 EDP43884.1 - 0.099 11.8 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Aldedh PF00171.17 EDP43885.1 - 8.2e-151 502.4 0.2 9.3e-151 502.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidohydro_1 PF01979.15 EDP43885.1 - 0.088 12.4 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family RNase_H PF00075.19 EDP43886.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 RNase H CHCH PF06747.8 EDP43887.1 - 0.012 15.5 6.0 0.014 15.2 0.4 2.4 2 1 0 2 2 2 0 CHCH domain ChaC PF04752.7 EDP43888.1 - 3.5e-49 167.1 0.0 8.7e-49 165.8 0.0 1.7 2 0 0 2 2 2 1 ChaC-like protein DnaJ PF00226.26 EDP43888.1 - 2.8e-24 84.6 1.5 8.2e-24 83.1 1.0 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EDP43888.1 - 2.1e-09 37.2 1.5 3.9e-09 36.3 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDP43888.1 - 6.9e-08 32.4 1.6 1.3e-07 31.5 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDP43888.1 - 0.0099 15.9 1.5 0.02 15.0 0.4 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_16 PF10294.4 EDP43889.1 - 1.1e-16 60.8 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDP43889.1 - 0.00012 22.6 0.0 0.00048 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDP43889.1 - 0.0036 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EDP43889.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EDP43889.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EDP43889.1 - 0.098 13.1 0.0 0.47 10.9 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain FtsJ PF01728.14 EDP43890.1 - 1.3e-33 116.5 0.7 2.6e-33 115.5 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EDP43890.1 - 0.00012 21.3 0.0 0.0014 17.9 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 EDP43890.1 - 0.018 15.6 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF3678 PF12435.3 EDP43890.1 - 0.14 11.7 1.6 0.29 10.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Sugar_tr PF00083.19 EDP43891.1 - 2.7e-84 283.3 17.6 3.1e-84 283.1 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP43891.1 - 2.7e-15 55.9 27.4 2.7e-15 55.9 19.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhoD PF09423.5 EDP43892.1 - 1.5e-06 27.1 0.0 0.00079 18.1 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Pectate_lyase_3 PF12708.2 EDP43894.1 - 1.4e-30 107.0 6.9 2.3e-15 57.3 0.8 2.1 2 0 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 EDP43894.1 - 0.0049 16.6 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region End_N_terminal PF12218.3 EDP43894.1 - 0.0092 15.4 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase GST_C PF00043.20 EDP43896.1 - 4.6e-08 32.9 0.1 8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDP43896.1 - 5.2e-08 32.9 0.0 9.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDP43896.1 - 1.5e-07 31.1 0.2 2.5e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDP43896.1 - 2.4e-06 27.4 0.0 4.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDP43896.1 - 0.00034 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cyt-b5 PF00173.23 EDP43897.1 - 5.2e-18 64.6 0.0 7.8e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arginase PF00491.16 EDP43898.1 - 5.2e-77 258.8 0.2 6.2e-77 258.6 0.2 1.0 1 0 0 1 1 1 1 Arginase family dCMP_cyt_deam_1 PF00383.17 EDP43899.1 - 1e-08 34.7 0.1 1.4e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EDP43899.1 - 0.0062 16.4 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase AAA PF00004.24 EDP43900.1 - 1.3e-90 300.3 0.0 1.7e-46 157.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDP43900.1 - 1.5e-13 50.3 0.0 2.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDP43900.1 - 9.6e-11 41.9 0.2 0.0026 17.8 0.0 5.0 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.9 EDP43900.1 - 2.1e-10 40.7 0.0 0.0013 18.7 0.0 3.0 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EDP43900.1 - 5.2e-10 39.3 0.0 0.00048 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDP43900.1 - 7.3e-10 39.7 0.0 0.00016 22.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP43900.1 - 8.3e-10 38.9 4.7 0.0018 18.3 0.0 4.2 3 2 1 4 4 3 2 AAA ATPase domain AAA_5 PF07728.9 EDP43900.1 - 1.2e-09 37.9 0.8 0.001 18.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDP43900.1 - 6.3e-08 31.7 0.0 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EDP43900.1 - 3.1e-07 29.7 0.7 0.026 13.6 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDP43900.1 - 3.9e-07 30.0 0.0 0.0043 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EDP43900.1 - 4.9e-07 29.8 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDP43900.1 - 6.8e-07 29.4 0.0 0.061 13.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EDP43900.1 - 1.7e-06 27.5 2.1 0.019 14.3 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_25 PF13481.1 EDP43900.1 - 2.1e-06 27.2 7.3 0.17 11.2 0.1 4.9 3 2 2 5 5 5 2 AAA domain Zeta_toxin PF06414.7 EDP43900.1 - 3.6e-06 26.2 0.0 0.012 14.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EDP43900.1 - 4.6e-06 26.2 2.2 0.097 12.4 0.0 4.4 4 0 0 4 4 4 2 Part of AAA domain NACHT PF05729.7 EDP43900.1 - 1.1e-05 25.1 1.3 0.5 10.0 0.0 3.6 3 1 1 4 4 3 2 NACHT domain AAA_3 PF07726.6 EDP43900.1 - 1.5e-05 24.6 0.0 0.065 12.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDP43900.1 - 2.7e-05 24.4 0.0 0.34 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EDP43900.1 - 4.2e-05 23.8 0.3 0.084 13.1 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Sigma54_activ_2 PF14532.1 EDP43900.1 - 6.6e-05 22.9 0.0 0.37 10.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EDP43900.1 - 7.7e-05 22.6 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family KaiC PF06745.8 EDP43900.1 - 0.00022 20.4 0.1 1.6 7.8 0.0 3.2 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.13 EDP43900.1 - 0.00026 20.5 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EDP43900.1 - 0.00061 19.6 0.1 0.97 9.2 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 EDP43900.1 - 0.0011 18.4 0.1 0.3 10.5 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EDP43900.1 - 0.0025 16.7 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EDP43900.1 - 0.0025 16.5 0.0 0.74 8.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein PhoH PF02562.11 EDP43900.1 - 0.004 16.4 0.4 1.3 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 EDP43900.1 - 0.0046 15.8 0.6 0.32 9.7 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain ResIII PF04851.10 EDP43900.1 - 0.0064 16.3 0.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EDP43900.1 - 0.0094 15.5 0.2 5.5 6.4 0.0 2.8 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.8 EDP43900.1 - 0.013 14.4 0.0 0.039 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EDP43900.1 - 0.018 14.6 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EDP43900.1 - 0.032 13.7 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EDP43900.1 - 0.043 13.5 0.0 1.8 8.1 0.0 3.2 2 2 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EDP43900.1 - 0.061 12.9 0.1 7.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EDP43900.1 - 0.074 11.8 0.0 4.4 5.9 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.10 EDP43900.1 - 0.14 11.8 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 NTPase P21-Arc PF04062.9 EDP43901.1 - 4.3e-70 235.0 0.0 4.8e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit PCI PF01399.22 EDP43902.1 - 4.7e-13 49.3 0.0 2.7e-12 46.9 0.0 2.3 1 1 1 2 2 2 1 PCI domain TFIIE_alpha PF02002.12 EDP43902.1 - 0.058 12.9 0.5 0.23 10.9 0.0 2.2 2 1 1 3 3 3 0 TFIIE alpha subunit Sybindin PF04099.7 EDP43903.1 - 6.7e-37 126.3 0.0 7.4e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDP43903.1 - 6.3e-07 29.3 0.0 6.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF1926 PF09095.6 EDP43903.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) 2-Hacid_dh_C PF02826.14 EDP43905.1 - 1.7e-51 173.8 0.0 3.1e-51 173.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDP43905.1 - 9.6e-18 63.9 0.0 3.2e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.15 EDP43905.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EDP43905.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NIF PF03031.13 EDP43906.1 - 2.1e-34 118.5 0.0 3.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_16 PF10294.4 EDP43907.1 - 1.1e-16 60.8 0.0 1.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDP43907.1 - 1.5e-05 25.5 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP43907.1 - 0.0008 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDP43907.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDP43907.1 - 0.0029 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP43907.1 - 0.065 13.6 0.0 0.22 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 EDP43907.1 - 0.077 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF43 UPF0052 PF01933.13 EDP43907.1 - 0.13 11.5 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Methyltransf_31 PF13847.1 EDP43907.1 - 0.17 11.5 0.1 1 8.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MRP-S28 PF10213.4 EDP43908.1 - 4.1e-23 81.8 0.0 8.6e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein RRP7 PF12923.2 EDP43909.1 - 2.6e-25 88.9 6.8 4.2e-23 81.7 4.0 2.2 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EDP43909.1 - 2.6e-07 30.1 0.0 1.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43909.1 - 0.0021 17.9 0.0 0.0081 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.12 EDP43909.1 - 0.053 13.8 2.9 0.38 11.1 1.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L14 MCM PF00493.18 EDP43910.1 - 6.6e-134 445.8 0.2 1.1e-133 445.1 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDP43910.1 - 9.2e-17 61.6 0.0 2.5e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDP43910.1 - 1.6e-08 33.9 0.0 5.8e-07 28.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDP43910.1 - 0.00069 19.1 0.1 0.0016 17.9 0.1 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDP43910.1 - 0.0033 17.0 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AICARFT_IMPCHas PF01808.13 EDP43910.1 - 0.025 13.6 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 0 AICARFT/IMPCHase bienzyme Tir_receptor_M PF03549.9 EDP43910.1 - 0.029 14.4 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain AAA_5 PF07728.9 EDP43910.1 - 0.035 13.8 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Asp PF00026.18 EDP43912.1 - 1.2e-44 152.8 4.8 5.1e-44 150.8 3.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EDP43912.1 - 1.3e-05 24.8 0.1 8e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDP43912.1 - 0.0001 22.7 1.7 0.045 14.2 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease Cu-oxidase_2 PF07731.9 EDP43913.1 - 2.6e-26 91.7 0.6 3.1e-26 91.5 0.4 1.1 1 0 0 1 1 1 1 Multicopper oxidase LIP PF03583.9 EDP43914.1 - 7.1e-62 209.2 0.0 9.4e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EDP43914.1 - 2.2e-06 27.4 0.0 6.1e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP43914.1 - 9.2e-06 25.6 0.0 0.00021 21.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDP43914.1 - 0.012 14.8 6.0 0.76 8.9 0.4 3.2 2 1 1 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EDP43914.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein His_Phos_2 PF00328.17 EDP43915.1 - 1.4e-38 133.1 0.0 2.2e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NMT1 PF09084.6 EDP43916.1 - 1.1e-48 165.7 0.0 1.4e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like PBP_like PF12727.2 EDP43916.1 - 0.041 12.8 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain NMT1_2 PF13379.1 EDP43916.1 - 0.058 12.7 0.1 0.39 10.0 0.0 1.9 1 1 0 2 2 2 0 NMT1-like family Thi4 PF01946.12 EDP43917.1 - 4.4e-87 290.9 0.0 5.3e-87 290.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EDP43917.1 - 1e-08 34.5 1.1 5.6e-08 32.0 0.7 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDP43917.1 - 1.2e-07 31.6 0.2 3.5e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDP43917.1 - 1.9e-06 27.0 0.3 2.8e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDP43917.1 - 3.8e-06 26.0 1.2 2.6e-05 23.2 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EDP43917.1 - 8.2e-06 25.6 0.1 8.9e-05 22.3 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDP43917.1 - 4.6e-05 23.3 0.0 7.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP43917.1 - 0.00017 21.6 0.7 0.0027 17.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP43917.1 - 0.00032 19.2 0.4 0.00049 18.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EDP43917.1 - 0.00047 19.1 0.0 0.0086 14.9 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DUF4387 PF14330.1 EDP43917.1 - 0.038 14.3 0.0 0.092 13.0 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4387) Trp_halogenase PF04820.9 EDP43917.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EDP43917.1 - 1.3 8.0 8.8 0.025 13.6 0.7 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase ERCC4 PF02732.10 EDP43920.1 - 5.1e-24 84.6 0.0 1.2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain Peptidase_M17 PF00883.16 EDP43921.1 - 6.9e-115 383.1 0.0 8.8e-115 382.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EDP43921.1 - 0.0026 17.4 0.0 0.0058 16.3 0.0 1.6 1 1 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DAO PF01266.19 EDP43922.1 - 1.4e-44 152.5 0.2 1.6e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDP43922.1 - 3.4e-07 30.5 1.0 0.004 17.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDP43922.1 - 0.0002 21.3 0.9 0.006 16.4 0.6 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP43922.1 - 0.0019 18.2 0.1 0.0051 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDP43922.1 - 0.0028 16.7 0.2 0.0057 15.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EDP43922.1 - 0.05 12.0 0.4 0.36 9.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein RRM_1 PF00076.17 EDP43923.1 - 9.3e-09 34.8 0.0 4.4e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43923.1 - 2.1e-08 34.0 0.0 3.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP43923.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF221 PF02714.10 EDP43924.1 - 1.9e-81 273.4 18.3 2.3e-81 273.1 12.7 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EDP43924.1 - 0.023 14.5 0.3 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 Phosphate metabolism protein tRNA_int_end_N2 PF12928.2 EDP43925.1 - 4.6e-20 70.8 0.0 6.4e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EDP43925.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Adap_comp_sub PF00928.16 EDP43926.1 - 5.3e-65 219.1 0.2 6.4e-65 218.8 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 EDP43926.1 - 3.6e-05 23.0 0.1 6.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.15 EDP43926.1 - 0.00011 21.9 1.0 0.00022 20.9 0.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_hydro_47 PF01532.15 EDP43927.1 - 2.4e-91 306.6 0.0 2.7e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 EDP43928.1 - 3.2e-45 154.6 0.0 3.7e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_transf_20 PF00982.16 EDP43929.1 - 5.2e-131 437.3 0.1 7.4e-131 436.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDP43929.1 - 1.7e-73 246.4 0.0 2.5e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase SH3_2 PF07653.12 EDP43929.1 - 0.066 12.7 0.1 2.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Variant SH3 domain Dor1 PF04124.7 EDP43931.1 - 6.2e-09 34.7 8.2 1.3e-08 33.7 4.7 1.9 2 0 0 2 2 2 1 Dor1-like family SMC_hinge PF06470.8 EDP43932.1 - 1.1e-32 112.4 0.3 2.9e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EDP43932.1 - 7.4e-08 31.8 7.5 7.4e-08 31.8 5.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF3533 PF12051.3 EDP43933.1 - 1.3e-87 294.0 13.0 1.6e-87 293.7 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Lipase_3 PF01764.20 EDP43934.1 - 6.1e-19 68.0 0.0 8.1e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF3125 PF11323.3 EDP43934.1 - 0.021 14.6 0.2 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3125) DUF2974 PF11187.3 EDP43934.1 - 0.049 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sel1 PF08238.7 EDP43935.1 - 9.7e-31 105.5 30.3 3.3e-05 24.3 0.4 8.3 8 0 0 8 8 8 7 Sel1 repeat Exo_endo_phos PF03372.18 EDP43937.1 - 1.6e-22 80.6 0.0 2.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EDP43937.1 - 9.3e-12 44.2 4.3 3.2e-05 23.4 0.9 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP43937.1 - 1.8e-09 37.1 2.0 6e-06 25.9 0.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EDP43937.1 - 2e-05 23.9 1.8 5.3 7.4 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EDP43937.1 - 0.0051 16.7 4.5 26 5.6 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EDP43937.1 - 0.13 12.4 0.4 35 4.9 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich repeat HSP90 PF00183.13 EDP43938.1 - 5.5e-251 833.5 31.0 6.5e-251 833.3 21.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EDP43938.1 - 1.2e-11 44.2 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDP43938.1 - 1.4e-11 44.2 0.2 1.4e-11 44.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 EDP43938.1 - 0.07 12.6 1.1 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF399 Peptidase_C37 PF05416.7 EDP43938.1 - 0.59 8.3 10.5 0.22 9.7 0.3 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Bystin PF05291.6 EDP43939.1 - 2e-130 434.1 0.0 3.2e-130 433.4 0.0 1.2 1 0 0 1 1 1 1 Bystin Adaptin_N PF01602.15 EDP43940.1 - 1.8e-80 270.7 0.1 2.6e-80 270.2 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDP43940.1 - 1.7e-07 31.4 5.3 0.00074 19.7 0.0 5.1 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EDP43940.1 - 2.6e-06 27.0 9.1 0.99 9.6 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.2 EDP43940.1 - 0.001 18.9 0.0 0.018 14.8 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EDP43940.1 - 0.0053 17.1 12.6 5.8 7.5 0.1 6.2 6 1 1 7 7 7 2 HEAT-like repeat DUF4357 PF14267.1 EDP43940.1 - 0.029 13.9 0.3 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Phos_pyr_kin PF08543.7 EDP43941.1 - 5.6e-37 127.2 0.0 2.3e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EDP43941.1 - 4e-34 118.2 0.6 6.8e-34 117.4 0.4 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF3077 PF11275.3 EDP43941.1 - 0.45 10.5 4.1 5.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3077) BSD PF03909.12 EDP43942.1 - 0.16 11.7 3.6 6.7 6.5 0.1 3.6 2 1 1 3 3 3 0 BSD domain Thiolase_N PF00108.18 EDP43943.1 - 9.8e-82 273.8 0.1 1.3e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDP43943.1 - 2.4e-47 159.4 0.3 5.8e-47 158.1 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDP43943.1 - 2.4e-05 23.9 0.6 5.3e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAPS PF04499.10 EDP43944.1 - 5.1e-127 424.4 0.2 6.3e-127 424.1 0.1 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.14 EDP43944.1 - 0.8 7.4 2.1 1.2 6.8 1.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Malate_synthase PF01274.17 EDP43945.1 - 5.8e-208 691.1 0.0 6.5e-208 690.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EDP43945.1 - 0.082 11.7 0.0 0.2 10.4 0.0 1.6 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Gar1 PF04410.9 EDP43946.1 - 8.1e-37 126.0 0.0 1.8e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region T2SM PF04612.7 EDP43946.1 - 0.17 11.6 1.2 0.44 10.3 0.9 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Cyt-b5 PF00173.23 EDP43947.1 - 0.0012 18.5 0.0 0.47 10.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Pyrophosphatase PF00719.14 EDP43947.1 - 0.067 12.6 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase DUF4065 PF13274.1 EDP43947.1 - 0.093 13.4 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) FA_desaturase PF00487.19 EDP43948.1 - 9.7e-21 74.3 32.1 2.3e-20 73.1 22.2 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DBR1 PF05011.8 EDP43949.1 - 2.8e-18 66.1 0.1 4.8e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EDP43949.1 - 6.2e-06 25.7 0.3 1.1e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M16 PF00675.15 EDP43950.1 - 7.9e-41 139.2 0.7 8.1e-40 135.9 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDP43950.1 - 1.9e-38 132.0 0.0 6.4e-23 81.3 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF87 PF01935.12 EDP43950.1 - 0.07 12.9 3.0 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Enolase_C PF00113.17 EDP43951.1 - 5.2e-118 393.3 0.4 6.2e-118 393.0 0.3 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.1 EDP43951.1 - 8e-06 25.7 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EDP43951.1 - 0.0044 16.0 0.2 0.0066 15.4 0.2 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EDP43951.1 - 0.096 13.2 0.0 0.17 12.4 0.0 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Enolase_N PF03952.11 EDP43952.1 - 1.3e-57 193.4 0.1 1.5e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain Lactamase_B PF00753.22 EDP43953.1 - 0.00052 19.7 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rrn6 PF10214.4 EDP43954.1 - 4.6e-07 28.3 0.3 4.6e-07 28.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor PNRC PF15365.1 EDP43955.1 - 5.5e-06 26.2 1.3 5.5e-06 26.2 0.9 2.6 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator DUF3519 PF12033.3 EDP43955.1 - 3.7 7.7 8.8 5.9 7.1 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) DUF1325 PF07039.6 EDP43956.1 - 1.2e-23 83.1 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain RF-1 PF00472.15 EDP43957.1 - 1.5e-37 127.8 2.7 1.5e-37 127.8 1.9 2.4 2 1 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EDP43957.1 - 3.1e-25 88.1 0.2 3.1e-25 88.1 0.1 1.9 2 0 0 2 2 2 1 PCRF domain Mo25 PF08569.6 EDP43957.1 - 0.26 10.3 4.5 0.39 9.6 3.1 1.2 1 0 0 1 1 1 0 Mo25-like Adaptin_N PF01602.15 EDP43958.1 - 1.7e-87 293.9 9.8 1.7e-87 293.9 6.8 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EDP43958.1 - 1.2e-63 212.6 0.0 5e-63 210.6 0.0 2.2 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EDP43958.1 - 1.2e-60 203.2 0.2 3.2e-60 201.8 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EDP43958.1 - 2.6e-12 46.8 5.3 7.4e-05 22.9 0.0 5.0 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EDP43958.1 - 5.7e-05 23.0 6.5 0.038 13.8 0.0 4.5 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EDP43958.1 - 0.00022 21.2 2.2 0.021 14.7 0.0 3.2 3 0 0 3 3 3 1 Parkin co-regulated protein HEAT PF02985.17 EDP43958.1 - 0.00049 19.9 0.1 0.29 11.3 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EDP43958.1 - 0.037 13.8 0.9 5.7 6.9 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Met_10 PF02475.11 EDP43958.1 - 0.043 13.3 1.0 0.098 12.2 0.2 2.0 2 0 0 2 2 2 0 Met-10+ like-protein HEAT_EZ PF13513.1 EDP43958.1 - 0.23 11.9 6.9 15 6.2 0.0 5.1 4 2 1 5 5 5 0 HEAT-like repeat SPX PF03105.14 EDP43959.1 - 5.9e-10 39.3 0.5 2.7e-09 37.2 0.0 2.0 2 1 0 2 2 2 1 SPX domain zf-C3HC4_2 PF13923.1 EDP43959.1 - 2e-05 24.5 14.3 3.6e-05 23.6 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDP43959.1 - 3.1e-05 23.7 12.4 5.9e-05 22.8 8.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EDP43959.1 - 4.4e-05 23.0 12.8 8e-05 22.2 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP43959.1 - 0.00011 22.0 13.2 0.0002 21.1 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDP43959.1 - 0.00015 21.3 9.9 0.00025 20.6 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP43959.1 - 0.00033 20.3 11.3 0.00064 19.3 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EDP43959.1 - 0.025 14.1 5.9 0.052 13.1 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDP43959.1 - 0.27 11.0 11.1 0.77 9.5 7.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EDP43959.1 - 0.29 10.7 5.9 0.7 9.4 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ABC_tran PF00005.22 EDP43961.1 - 5.7e-35 120.6 0.1 8.9e-17 61.6 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDP43961.1 - 3.7e-14 53.3 2.8 0.046 13.6 0.0 4.3 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 EDP43961.1 - 1.5e-13 50.0 4.2 1.5e-13 50.0 2.9 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 EDP43961.1 - 1.4e-10 40.7 4.9 0.00015 21.0 0.3 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EDP43961.1 - 1.1e-07 31.0 3.2 1.1e-07 31.0 2.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_15 PF13175.1 EDP43961.1 - 1.2e-07 31.1 3.0 0.32 9.9 0.1 4.6 5 0 0 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EDP43961.1 - 1.8e-06 28.1 0.1 0.0021 18.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 EDP43961.1 - 2.1e-06 27.3 11.5 4.1e-05 23.2 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain AAA PF00004.24 EDP43961.1 - 5.4e-06 26.6 0.1 0.022 14.9 0.1 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDP43961.1 - 2.1e-05 24.0 0.1 0.017 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP43961.1 - 3.4e-05 23.5 1.3 0.0036 16.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.2 EDP43961.1 - 5.9e-05 23.3 6.5 0.00025 21.3 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_29 PF13555.1 EDP43961.1 - 7.1e-05 22.2 1.2 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDP43961.1 - 0.0001 23.0 0.0 0.63 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDP43961.1 - 0.00011 21.4 3.9 0.066 12.4 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EDP43961.1 - 0.00028 21.3 0.1 0.58 10.6 0.0 3.1 3 0 0 3 3 2 1 Miro-like protein VirE PF05272.6 EDP43961.1 - 0.00032 20.2 0.0 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E RNA_helicase PF00910.17 EDP43961.1 - 0.00067 19.8 0.3 0.18 11.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.1 EDP43961.1 - 0.00068 19.9 0.6 0.41 10.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 EDP43961.1 - 0.0007 19.3 2.4 0.0007 19.3 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 EDP43961.1 - 0.00073 19.3 12.3 0.0015 18.3 8.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.1 EDP43961.1 - 0.00091 19.1 0.5 0.098 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP43961.1 - 0.0012 18.9 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EDP43961.1 - 0.0016 18.3 0.0 2.8 7.9 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 EDP43961.1 - 0.0019 18.9 4.9 0.004 17.8 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_14 PF13173.1 EDP43961.1 - 0.0022 17.8 0.5 1.6 8.6 0.0 3.2 2 2 0 2 2 2 1 AAA domain MobB PF03205.9 EDP43961.1 - 0.0024 17.6 1.8 0.29 10.8 0.1 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_10 PF13237.1 EDP43961.1 - 0.0038 17.0 1.6 0.0038 17.0 1.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDP43961.1 - 0.0051 17.0 2.4 0.0051 17.0 1.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain UPF0079 PF02367.12 EDP43961.1 - 0.0077 15.8 0.5 0.059 12.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EDP43961.1 - 0.0081 16.1 0.4 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDP43961.1 - 0.012 15.0 3.6 0.34 10.3 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EDP43961.1 - 0.014 14.2 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fer4_3 PF12798.2 EDP43961.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.4 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_23 PF13476.1 EDP43961.1 - 0.018 15.3 0.9 0.018 15.3 0.6 2.6 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 EDP43961.1 - 0.048 12.3 0.0 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fer4_17 PF13534.1 EDP43961.1 - 0.051 13.9 0.2 0.051 13.9 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EDP43961.1 - 0.056 13.0 1.5 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EDP43961.1 - 0.08 12.3 1.0 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Fer4_8 PF13183.1 EDP43961.1 - 0.087 12.8 8.7 0.29 11.1 6.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.18 EDP43961.1 - 0.098 12.6 0.0 9.2 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_4 PF12800.2 EDP43961.1 - 0.19 12.1 13.2 0.055 13.8 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_5 PF07728.9 EDP43961.1 - 0.23 11.2 2.0 2.7 7.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Fer4_15 PF13459.1 EDP43961.1 - 2.1 8.9 7.7 0.085 13.4 0.7 2.2 2 0 0 2 2 1 0 4Fe-4S single cluster domain SNF2_N PF00176.18 EDP43962.1 - 1.2e-42 145.7 0.0 1.5e-35 122.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP43962.1 - 7.9e-09 35.2 0.0 2.1e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP43962.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase KH_1 PF00013.24 EDP43963.1 - 6.2e-05 22.5 0.1 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDP43963.1 - 0.0002 20.8 0.0 0.00049 19.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EDP43963.1 - 0.059 13.0 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 KH domain FHA PF00498.21 EDP43964.1 - 3.3e-18 65.5 0.0 6.4e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EDP43964.1 - 3.7e-09 36.2 10.7 6.3e-09 35.5 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDP43964.1 - 0.00051 19.7 8.7 0.00085 19.0 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDP43964.1 - 0.00072 19.6 5.4 0.0017 18.4 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDP43964.1 - 0.00079 19.0 10.6 0.0014 18.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP43964.1 - 0.0052 16.4 9.1 0.0092 15.6 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.9 EDP43964.1 - 0.013 14.6 0.4 0.03 13.5 0.3 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 EDP43964.1 - 0.024 14.6 12.6 0.042 13.8 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDP43964.1 - 0.067 13.0 4.3 0.12 12.2 3.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EDP43964.1 - 0.27 10.9 5.0 0.67 9.6 3.5 1.7 1 0 0 1 1 1 0 PHD-finger DEAD PF00270.24 EDP43965.1 - 5.5e-48 162.6 0.1 8.7e-46 155.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43965.1 - 8.9e-25 86.3 0.0 2e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDP43965.1 - 6.1e-06 24.8 0.2 0.00015 20.3 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EDP43965.1 - 0.077 13.1 1.1 0.21 11.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDP43965.1 - 0.21 11.3 2.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain IF-2B PF01008.12 EDP43966.1 - 1.5e-57 194.7 0.0 1.8e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pkinase PF00069.20 EDP43967.1 - 2.7e-55 187.3 0.0 3.2e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP43967.1 - 4.1e-25 88.3 0.1 4.8e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP43967.1 - 8.9e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP43967.1 - 0.045 13.4 0.1 0.085 12.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Got1 PF04178.7 EDP43968.1 - 1.8e-19 69.9 13.8 2.1e-19 69.7 9.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4405 PF14358.1 EDP43968.1 - 1.3 9.1 7.8 0.2 11.8 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) Lipase_GDSL PF00657.17 EDP43969.1 - 1.5e-22 80.5 0.5 1.9e-22 80.2 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDP43969.1 - 4e-08 33.5 4.0 1.8e-07 31.5 2.8 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AAA_10 PF12846.2 EDP43969.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Sec23_trunk PF04811.10 EDP43970.1 - 3.8e-64 216.3 0.0 6.1e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDP43970.1 - 1.7e-20 72.3 0.6 3.7e-20 71.2 0.2 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDP43970.1 - 2.1e-16 59.2 5.9 3.4e-16 58.5 4.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EDP43970.1 - 6.6e-15 55.3 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDP43970.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat Collagen PF01391.13 EDP43970.1 - 0.72 9.4 2.2 1.4 8.5 1.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sporozoite_P67 PF05642.6 EDP43970.1 - 7.1 4.3 9.5 10 3.8 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRM_1 PF00076.17 EDP43971.1 - 1.2e-06 27.9 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP43971.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FimP PF09766.4 EDP43972.1 - 3.3e-06 26.4 13.9 7.9e-06 25.1 9.6 1.5 1 1 0 1 1 1 1 Fms-interacting protein Fib_alpha PF08702.5 EDP43972.1 - 0.31 11.1 4.4 0.35 10.9 2.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 EDP43972.1 - 0.32 10.3 4.0 0.32 10.3 1.9 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GCN5L1 PF06320.8 EDP43972.1 - 0.36 10.6 5.6 0.65 9.8 1.5 2.3 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) BLOC1_2 PF10046.4 EDP43972.1 - 0.51 10.4 6.7 4.7 7.4 0.4 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Kinesin-relat_1 PF12711.2 EDP43972.1 - 0.61 10.5 10.3 0.6 10.5 3.3 2.7 1 1 1 2 2 2 0 Kinesin motor Adeno_PIX PF03955.9 EDP43972.1 - 1.3 9.6 9.3 1.1 9.8 1.6 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) HALZ PF02183.13 EDP43972.1 - 1.6 8.4 14.9 0.19 11.4 0.9 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper Striatin PF08232.7 EDP43972.1 - 1.7 8.9 8.4 12 6.2 5.7 2.1 1 1 0 1 1 1 0 Striatin family DUF4337 PF14235.1 EDP43972.1 - 2.7 7.8 13.4 0.16 11.7 3.7 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Nsp1_C PF05064.8 EDP43972.1 - 5.9 6.5 9.1 1.8 8.2 2.7 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Peptidase_C50 PF03568.12 EDP43973.1 - 2.1e-75 253.7 0.0 3.4e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 SPA PF08616.5 EDP43974.1 - 1.5e-29 102.0 0.0 3.1e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EDP43974.1 - 5.6e-21 75.0 0.0 2.4e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking GCFC PF07842.7 EDP43976.1 - 2e-70 237.2 9.2 2.9e-70 236.7 6.4 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EDP43976.1 - 8.6e-12 44.6 0.5 8.6e-12 44.6 0.3 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EDP43976.1 - 1.6e-06 27.8 0.4 8.3e-05 22.3 0.1 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site ASFV_J13L PF05568.6 EDP43976.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein RXT2_N PF08595.6 EDP43976.1 - 4.6 7.0 5.5 9.6 5.9 3.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cyclin_N PF00134.18 EDP43977.1 - 1e-10 41.2 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EDP43977.1 - 0.0026 17.5 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EDP43977.1 - 0.0065 16.3 1.9 0.88 9.5 0.0 2.9 2 1 1 3 3 3 2 Cyclin, C-terminal domain TPP_enzyme_N PF02776.13 EDP43978.1 - 2.5e-53 180.0 0.3 1.3e-52 177.7 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDP43978.1 - 1.8e-48 164.0 0.1 1.7e-46 157.5 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDP43978.1 - 3.4e-38 130.4 1.1 1.6e-37 128.3 0.3 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EDP43978.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CUE PF02845.11 EDP43979.1 - 0.025 14.0 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 CUE domain Ank_2 PF12796.2 EDP43981.1 - 4.7e-12 46.0 1.1 7.1e-12 45.4 0.8 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP43981.1 - 1.6e-11 44.3 1.6 2.3e-05 24.7 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP43981.1 - 6.3e-08 32.6 4.8 1.3e-05 25.2 0.4 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP43981.1 - 7.1e-08 31.9 2.1 0.092 13.0 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 EDP43981.1 - 2.8e-06 26.8 3.8 0.055 13.3 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat Nrap PF03813.9 EDP43982.1 - 3.4e-233 776.3 0.0 3.9e-233 776.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein PI31_Prot_C PF08577.6 EDP43983.1 - 2.1e-05 25.0 13.3 2.1e-05 25.0 9.2 1.8 2 0 0 2 2 2 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 EDP43983.1 - 0.052 13.1 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal GPP34 PF05719.6 EDP43985.1 - 1.7e-55 188.2 0.3 2.1e-55 187.9 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Rifin_STEVOR PF02009.11 EDP43986.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family GRAM PF02893.15 EDP43987.1 - 1.4e-17 62.9 0.1 5e-17 61.1 0.0 2.0 2 0 0 2 2 2 1 GRAM domain DUF4611 PF15387.1 EDP43987.1 - 0.64 10.1 7.2 6.5 6.9 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DEAD PF00270.24 EDP43988.1 - 6.6e-39 133.1 0.0 1.7e-38 131.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP43988.1 - 4.3e-19 68.1 0.0 1.1e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDP43988.1 - 1.9e-17 62.5 0.0 4.6e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDP43988.1 - 3.2e-05 23.8 0.0 9.9e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDP43988.1 - 0.12 11.4 5.5 0.21 10.6 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pribosyl_synth PF14572.1 EDP43989.1 - 7e-34 117.1 2.6 1.2e-32 113.2 1.8 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDP43989.1 - 4.1e-20 71.6 3.7 1.7e-19 69.6 0.2 2.8 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDP43989.1 - 2.8e-13 49.6 0.1 2e-12 46.9 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDP43989.1 - 0.0048 16.1 0.2 0.0081 15.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EDP43989.1 - 0.17 11.1 2.3 0.15 11.3 0.1 1.8 2 1 0 2 2 2 0 Phosphoribosyl transferase PduV-EutP PF10662.4 EDP43989.1 - 0.31 10.5 3.4 12 5.4 0.0 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PWI PF01480.12 EDP43990.1 - 8.1e-27 93.1 0.0 1.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 PWI domain GVQW PF13900.1 EDP43990.1 - 0.19 11.7 4.1 0.41 10.6 2.9 1.6 1 0 0 1 1 1 0 Putative binding domain WD40 PF00400.27 EDP43991.1 - 2.1e-69 227.0 15.0 4.6e-11 42.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EDP43991.1 - 4.3e-06 26.8 0.5 8e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Tup N-terminal eIF2A PF08662.6 EDP43991.1 - 2.2e-05 24.2 0.0 1.2 8.8 0.0 4.1 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EDP43991.1 - 0.00013 20.8 0.5 0.019 13.7 0.1 2.6 2 1 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EDP43991.1 - 0.00029 20.4 0.1 22 4.8 0.0 4.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EDP43991.1 - 0.00074 18.7 0.0 0.51 9.3 0.0 3.4 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EDP43991.1 - 0.019 14.3 3.2 32 3.9 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 EDP43991.1 - 0.036 12.3 0.0 0.24 9.6 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain PX PF00787.19 EDP43992.1 - 1.6e-14 53.6 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EDP43992.1 - 1e-06 28.3 4.4 1.7e-06 27.6 3.0 1.4 1 0 0 1 1 1 1 SNARE domain INCENP_ARK-bind PF03941.10 EDP43993.1 - 1.9e-07 30.8 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Galactosyl_T PF01762.16 EDP43994.1 - 8e-10 38.6 0.6 2.4e-06 27.2 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase DUF499 PF04465.7 EDP43995.1 - 0.0068 14.0 0.0 0.0085 13.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF499) E1-E2_ATPase PF00122.15 EDP43997.1 - 5.5e-10 38.6 0.0 2.7e-09 36.4 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDP43998.1 - 7.4e-10 39.6 0.1 0.0007 20.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDP43998.1 - 5.9e-09 36.3 0.0 1.7e-08 34.8 0.0 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDP43998.1 - 0.00016 21.3 0.6 0.0025 17.4 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_1 PF00441.19 EDP43999.1 - 6.9e-47 159.3 4.1 6.9e-47 159.3 2.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDP43999.1 - 6.7e-24 84.6 0.0 2.2e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDP43999.1 - 4.4e-23 82.0 1.9 4.4e-23 82.0 1.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDP43999.1 - 1.7e-17 62.6 0.0 3.3e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AgrD PF05931.6 EDP43999.1 - 0.011 15.2 0.1 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 Staphylococcal AgrD protein Tfb2 PF03849.9 EDP44000.1 - 1.1e-85 287.5 2.8 1.2e-85 287.3 2.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EDP44000.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDP44001.1 - 2e-64 217.2 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EDP44001.1 - 7.2e-38 130.3 0.3 1.3e-37 129.5 0.2 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EDP44001.1 - 7.8e-12 44.8 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP44001.1 - 0.0007 19.4 0.0 0.0078 16.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EDP44001.1 - 0.0083 14.9 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EDP44001.1 - 0.029 14.5 0.1 0.33 11.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain Glyco_hydro_16 PF00722.16 EDP44002.1 - 1.1e-06 28.0 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RNase_PH PF01138.16 EDP44003.1 - 8.1e-29 100.6 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TcdA_TcdB_pore PF12920.2 EDP44003.1 - 0.072 10.9 2.5 0.095 10.5 1.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Methyltransf_15 PF09445.5 EDP44004.1 - 2.3e-10 40.2 0.2 3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EDP44004.1 - 3.4e-05 23.8 0.0 5.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP44004.1 - 0.00072 19.1 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EDP44004.1 - 0.00092 18.8 0.1 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EDP44004.1 - 0.0034 16.8 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_25 PF13649.1 EDP44004.1 - 0.009 16.3 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP44004.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 EDP44004.1 - 0.032 13.7 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrmA PF06325.8 EDP44004.1 - 0.093 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EDP44004.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 EDP44005.1 - 1.3e-10 41.1 0.0 1.6e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UQ_con PF00179.21 EDP44006.1 - 2.7e-41 140.2 0.1 3e-41 140.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDP44006.1 - 3.8e-07 29.9 0.0 5.5e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDP44006.1 - 0.12 12.3 0.2 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 RWD domain Nol1_Nop2_Fmu_2 PF13636.1 EDP44006.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis Aminotran_1_2 PF00155.16 EDP44007.1 - 3.2e-37 128.3 0.0 3.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDP44007.1 - 0.0013 17.1 0.0 0.002 16.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EDP44007.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.27 EDP44008.1 - 1e-52 174.1 21.3 3.9e-11 42.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDP44008.1 - 0.00011 20.5 3.4 1.1 7.3 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Aldo_ket_red PF00248.16 EDP44009.1 - 9.6e-58 195.2 0.1 1.2e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 EDP44010.1 - 5.2e-13 48.4 4.5 3e-07 30.0 0.1 4.2 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EDP44010.1 - 1.7e-05 24.2 0.3 0.013 15.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44010.1 - 2.2e-05 24.6 11.0 0.15 12.7 0.4 7.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44010.1 - 6.9e-05 22.4 0.1 6.9e-05 22.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44010.1 - 0.00011 22.0 10.1 0.0076 16.1 0.1 6.0 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44010.1 - 0.00014 21.7 0.1 0.19 12.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44010.1 - 0.0019 18.7 7.2 0.67 10.7 0.0 5.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44010.1 - 0.0033 17.1 0.1 0.11 12.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EDP44010.1 - 0.85 9.7 5.1 1.9 8.6 0.2 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 F-box-like PF12937.2 EDP44011.1 - 5.7e-11 41.9 3.4 5.7e-11 41.9 2.4 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EDP44011.1 - 1.7e-08 33.9 0.4 2.8 7.6 0.0 6.2 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EDP44011.1 - 2.6e-08 33.0 5.1 2.4 8.4 0.0 8.9 9 1 1 10 10 10 1 Leucine Rich repeat LRR_8 PF13855.1 EDP44011.1 - 6.7e-08 32.1 5.5 0.68 9.7 0.0 6.1 5 1 2 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 EDP44011.1 - 1.4e-06 27.5 9.8 11 6.4 0.0 7.9 7 2 0 7 7 7 1 Leucine Rich Repeat F-box PF00646.28 EDP44011.1 - 0.00036 20.1 5.8 0.0012 18.4 0.3 4.1 4 0 0 4 4 4 1 F-box domain LRR_7 PF13504.1 EDP44011.1 - 0.061 13.5 14.1 6.8 7.3 0.1 6.2 7 0 0 7 7 7 0 Leucine rich repeat RNase_P_Rpp14 PF01900.14 EDP44011.1 - 0.071 13.0 0.1 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Rpp14/Pop5 family SMK-1 PF04802.10 EDP44011.1 - 0.091 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Coatomer_WDAD PF04053.9 EDP44012.1 - 8.5e-139 463.1 0.0 1.9e-138 462.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EDP44012.1 - 5.9e-52 171.8 14.9 6.1e-11 41.7 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDP44012.1 - 0.0078 14.4 0.1 0.2 9.7 0.0 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.26 EDP44013.1 - 5.6e-11 42.3 0.8 5.6e-11 42.3 0.5 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDP44013.1 - 1.1e-07 31.8 0.3 2.5e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sec2p PF06428.6 EDP44013.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Lzipper-MIP1 PF14389.1 EDP44013.1 - 0.82 9.8 10.1 6.8 6.8 1.7 3.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EDP44013.1 - 9.1 5.8 8.2 22 4.6 5.2 1.8 1 1 1 2 2 2 0 IncA protein Mod_r PF07200.8 EDP44014.1 - 0.0013 18.7 0.2 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PMSI1 PF15322.1 EDP44014.1 - 0.12 11.3 1.0 0.14 11.1 0.7 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ead_Ea22 PF13935.1 EDP44014.1 - 0.83 9.9 4.8 2 8.7 3.3 1.6 1 1 1 2 2 2 0 Ead/Ea22-like protein DUF202 PF02656.10 EDP44015.1 - 5.4e-12 45.7 7.0 5.4e-12 45.7 4.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pro_isomerase PF00160.16 EDP44016.1 - 1.9e-43 148.3 0.0 2.2e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2435 PF10363.4 EDP44017.1 - 1.6e-27 95.2 0.1 5.7e-27 93.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF3661 PF12400.3 EDP44018.1 - 1.3e-12 47.9 4.4 1.5e-12 47.7 3.1 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein GDPD PF03009.12 EDP44019.1 - 3.1e-14 53.0 0.0 4.1e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EDP44019.1 - 0.0023 18.0 1.2 0.0048 17.0 0.8 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Palm_thioest PF02089.10 EDP44020.1 - 3.3e-59 200.1 0.0 4.4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EDP44020.1 - 0.00029 20.4 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDP44020.1 - 0.003 17.4 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MBOAT PF03062.14 EDP44021.1 - 1.2e-42 146.2 7.9 1.2e-42 146.2 5.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Vps5 PF09325.5 EDP44022.1 - 7.5e-17 61.3 9.9 8.5e-17 61.1 6.3 1.5 1 1 0 1 1 1 1 Vps5 C terminal like Trypan_PARP PF05887.6 EDP44022.1 - 0.02 14.7 4.1 0.038 13.8 2.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 EDP44023.1 - 5.5e-25 86.2 5.7 1e-07 31.5 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP44023.1 - 0.098 12.9 0.2 2.8 8.3 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain GTP_EFTU PF00009.22 EDP44024.1 - 1.9e-38 131.7 0.1 2.9e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDP44024.1 - 2.8e-08 33.4 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDP44024.1 - 4.3e-06 26.7 0.0 9.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EDP44024.1 - 0.027 13.8 0.3 0.055 12.8 0.0 1.5 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.18 EDP44024.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_C PF00679.19 EDP44025.1 - 1.8e-13 50.1 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EDP44025.1 - 0.00021 20.8 0.0 0.00055 19.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor G, domain IV ADH_zinc_N_2 PF13602.1 EDP44027.1 - 2.8e-08 34.6 0.0 5.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP44027.1 - 5e-05 23.0 0.1 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP44027.1 - 0.0009 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Arginase PF00491.16 EDP44027.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Arginase family LRR_4 PF12799.2 EDP44028.1 - 9.5e-10 37.8 6.6 0.00015 21.2 0.7 4.2 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP44028.1 - 2.4e-08 33.5 4.1 1.6e-07 30.9 0.1 3.3 2 2 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EDP44028.1 - 5.7e-05 22.5 2.4 11 6.5 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 EDP44028.1 - 7.6e-05 22.3 1.4 24 5.4 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 EDP44028.1 - 0.00048 19.8 1.2 8.3 7.1 0.0 5.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_9 PF14580.1 EDP44028.1 - 0.0063 16.0 0.0 0.18 11.3 0.0 2.2 1 1 0 2 2 2 1 Leucine-rich repeat DUF3473 PF11959.3 EDP44028.1 - 0.12 11.8 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) RRM_1 PF00076.17 EDP44030.1 - 1e-20 73.1 0.0 2.9e-15 55.6 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44030.1 - 8e-12 44.9 0.0 5.9e-08 32.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44030.1 - 3e-11 42.9 0.0 1.1e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP44030.1 - 0.0011 18.7 0.0 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDP44030.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif X PF00739.14 EDP44030.1 - 0.17 11.7 5.3 0.36 10.7 3.6 1.5 1 0 0 1 1 1 0 Trans-activation protein X Ribosomal_L7Ae PF01248.21 EDP44031.1 - 1.1e-29 101.7 0.9 1.4e-29 101.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_S17 PF00366.15 EDP44032.1 - 3.3e-26 91.1 1.8 4.8e-26 90.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L1 PF00687.16 EDP44033.1 - 3.9e-51 173.5 2.5 4.7e-51 173.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Isy1 PF06246.7 EDP44034.1 - 7e-74 248.4 0.3 8.5e-74 248.1 0.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family CTP_transf_2 PF01467.21 EDP44035.1 - 0.059 13.4 0.0 0.64 10.0 0.0 2.2 2 1 0 2 2 2 0 Cytidylyltransferase TCTP PF00838.12 EDP44036.1 - 2.4e-61 206.5 0.8 2.7e-61 206.3 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 EDP44036.1 - 0.02 13.7 0.0 0.022 13.6 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family RcbX PF02341.10 EDP44036.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RbcX protein Cor1 PF04803.7 EDP44036.1 - 0.092 12.5 1.5 0.62 9.8 0.2 2.0 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region RRM_1 PF00076.17 EDP44037.1 - 2.2e-18 65.6 0.0 3.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44037.1 - 6.7e-11 42.0 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44037.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 EDP44038.1 - 5.7e-26 90.2 1.9 1.4e-25 88.9 1.3 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EDP44038.1 - 0.0044 16.7 0.8 3.6 7.5 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3548 PF12068.3 EDP44038.1 - 0.13 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Vac14_Fab1_bd PF12755.2 EDP44039.1 - 3.7e-44 149.0 0.0 1.5e-37 127.8 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDP44039.1 - 2e-16 58.4 8.1 0.00029 20.6 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EDP44039.1 - 1.6e-10 41.1 3.3 0.0007 19.8 0.1 4.5 4 0 0 4 4 4 3 HEAT repeats MMS19_C PF12460.3 EDP44039.1 - 9e-08 31.2 0.3 0.00015 20.6 0.0 2.5 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 EDP44039.1 - 1.6e-06 28.4 0.8 2.7 8.6 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 EDP44039.1 - 5.8e-05 23.0 0.0 0.047 13.5 0.0 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 EDP44039.1 - 0.0016 18.3 0.1 2.5 8.0 0.0 2.9 3 0 0 3 3 3 2 Exportin 1-like protein IFRD PF05004.8 EDP44039.1 - 0.0027 16.8 0.0 0.0073 15.4 0.0 1.6 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.3 EDP44039.1 - 0.015 14.7 0.1 5.2 6.3 0.0 3.8 4 0 0 4 4 4 0 CLASP N terminal Ecm29 PF13001.2 EDP44039.1 - 0.062 11.7 0.1 0.29 9.5 0.0 2.0 3 0 0 3 3 3 0 Proteasome stabiliser Arm PF00514.18 EDP44039.1 - 0.088 12.6 0.6 74 3.3 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UCH PF00443.24 EDP44040.1 - 2e-53 181.2 0.0 2.4e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP44040.1 - 4.2e-22 78.9 0.0 6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EDP44040.1 - 8.4e-05 21.9 0.2 0.44 9.7 0.2 2.8 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_C14 PF00656.17 EDP44041.1 - 8.2e-63 212.3 0.0 1e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EDP44041.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain SH3_9 PF14604.1 EDP44042.1 - 9.2e-14 50.7 0.2 2.1e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EDP44042.1 - 4.2e-12 46.1 0.0 8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EDP44042.1 - 6.3e-12 44.6 0.1 1.7e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDP44042.1 - 3.1e-07 29.7 0.1 5.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EDP44042.1 - 4.1e-07 29.7 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDP44042.1 - 0.017 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pou PF00157.12 EDP44042.1 - 0.12 12.0 0.1 0.55 9.9 0.0 2.0 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain Ste50p-SAM PF09235.5 EDP44042.1 - 0.16 11.9 0.2 0.3 11.1 0.2 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DnaJ PF00226.26 EDP44043.1 - 2.2e-20 72.1 1.5 4.2e-20 71.2 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain NOB1_Zn_bind PF08772.6 EDP44044.1 - 2.8e-28 97.5 0.3 5.8e-28 96.5 0.2 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EDP44044.1 - 0.00031 20.5 7.1 0.00085 19.1 3.4 2.3 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator DZR PF12773.2 EDP44044.1 - 0.031 14.0 1.6 0.061 13.1 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon BTV_NS2 PF04514.7 EDP44044.1 - 0.036 12.9 1.2 0.084 11.7 0.8 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cdc6_C PF09079.6 EDP44044.1 - 0.1 12.3 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal zf-ribbon_3 PF13248.1 EDP44044.1 - 0.18 11.0 4.9 0.36 10.0 3.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Sigma70_ner PF04546.8 EDP44044.1 - 0.63 9.6 6.1 1.2 8.7 4.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EDP44044.1 - 2.9 7.4 8.1 5 6.6 5.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin AcetDehyd-dimer PF09290.6 EDP44045.1 - 0.071 13.0 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation ox_reductase_C PF08635.5 EDP44046.1 - 1.8e-60 202.5 0.0 2.5e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EDP44046.1 - 1.3e-17 64.4 0.0 2.3e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDP44046.1 - 1.6e-05 24.6 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Cofilin_ADF PF00241.15 EDP44047.1 - 1.1e-08 35.0 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ox_reductase_C PF08635.5 EDP44048.1 - 4.8e-74 246.4 0.0 7e-74 245.9 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EDP44048.1 - 9.9e-22 77.7 0.0 1.9e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Clathrin_lg_ch PF01086.12 EDP44051.1 - 1.2e-32 113.6 23.9 1.7e-29 103.3 8.0 2.1 1 1 1 2 2 2 2 Clathrin light chain Ribosomal_L13 PF00572.13 EDP44052.1 - 8.6e-47 158.3 0.5 1.1e-46 158.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 SMC_N PF02463.14 EDP44054.1 - 2.3e-18 66.2 0.0 3.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDP44054.1 - 1.2e-14 55.1 5.6 7.1e-14 52.6 0.0 3.7 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 EDP44054.1 - 5.6e-06 26.5 0.0 0.00037 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain CENP-F_leu_zip PF10473.4 EDP44054.1 - 0.00051 19.9 24.8 0.00064 19.5 9.7 5.9 6 0 0 6 6 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.1 EDP44054.1 - 0.002 17.6 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EDP44054.1 - 0.0071 17.1 3.7 0.088 13.6 2.5 3.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP44054.1 - 0.04 13.6 0.1 0.2 11.4 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EDP44054.1 - 0.083 13.1 0.0 0.083 13.1 0.0 3.9 3 2 0 4 4 4 0 ABC transporter DUF2089 PF09862.4 EDP44054.1 - 0.086 12.6 1.8 0.41 10.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) AAA_25 PF13481.1 EDP44054.1 - 0.17 11.2 0.0 0.17 11.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EDP44054.1 - 0.52 8.6 0.0 0.52 8.6 0.0 4.5 4 1 1 5 5 5 0 AAA domain AAA PF00004.24 EDP44054.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.9 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) Cornichon PF03311.9 EDP44055.1 - 1e-50 171.1 12.0 1.2e-50 170.9 8.3 1.0 1 0 0 1 1 1 1 Cornichon protein CBFD_NFYB_HMF PF00808.18 EDP44056.1 - 5.2e-25 87.2 1.0 5.8e-25 87.1 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP44056.1 - 0.00013 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ABC_tran PF00005.22 EDP44057.1 - 9.3e-46 155.5 0.0 2.5e-22 79.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDP44057.1 - 3.2e-20 73.2 0.8 0.00025 21.1 0.0 4.5 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EDP44057.1 - 1.7e-19 69.4 3.7 1.7e-19 69.4 2.5 2.6 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.1 EDP44057.1 - 8e-11 42.6 3.8 0.00051 20.4 0.1 3.6 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EDP44057.1 - 2.2e-09 36.8 2.2 0.22 10.6 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDP44057.1 - 2.1e-08 33.5 5.0 0.00032 20.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDP44057.1 - 1.1e-07 32.6 0.3 0.01 16.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EDP44057.1 - 1.6e-06 27.4 12.2 0.084 11.9 0.0 5.0 3 2 1 5 5 5 3 AAA ATPase domain Miro PF08477.8 EDP44057.1 - 2.1e-06 28.2 0.0 0.14 12.6 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EDP44057.1 - 2.8e-06 27.5 0.3 0.017 15.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDP44057.1 - 3.5e-06 26.3 0.0 0.0019 17.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDP44057.1 - 3.8e-06 26.9 0.0 0.06 13.3 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EDP44057.1 - 6.9e-06 26.0 0.0 0.012 15.6 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDP44057.1 - 2e-05 24.8 2.0 0.1 12.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EDP44057.1 - 2.4e-05 24.0 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EDP44057.1 - 3.3e-05 23.5 1.1 0.25 11.0 0.1 3.5 2 1 1 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EDP44057.1 - 9.7e-05 21.9 0.0 0.46 9.9 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 EDP44057.1 - 0.00014 21.8 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDP44057.1 - 0.00026 20.4 0.0 0.47 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EDP44057.1 - 0.0003 20.6 2.8 1.2 8.9 0.0 4.1 3 1 1 4 4 4 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EDP44057.1 - 0.00031 20.6 5.6 0.33 10.7 0.2 3.7 3 1 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 EDP44057.1 - 0.00047 19.4 0.1 0.026 13.8 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 EDP44057.1 - 0.00049 19.6 0.0 0.51 9.7 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 EDP44057.1 - 0.00057 20.0 0.0 2.1 8.5 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDP44057.1 - 0.0014 18.5 0.0 0.52 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EDP44057.1 - 0.0025 17.9 1.1 4.8 7.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 EDP44057.1 - 0.0025 17.4 0.0 0.87 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EDP44057.1 - 0.0048 16.3 0.1 0.83 9.0 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EDP44057.1 - 0.0066 16.3 0.2 12 5.7 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.1 EDP44057.1 - 0.0073 14.8 1.2 1.7 7.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EDP44057.1 - 0.0092 15.8 0.0 0.77 9.7 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EDP44057.1 - 0.011 15.4 0.5 4.5 6.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDP44057.1 - 0.014 15.1 0.1 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EDP44057.1 - 0.015 15.0 1.3 3.7 7.2 0.1 3.6 4 0 0 4 4 3 0 NTPase LeuA_dimer PF08502.5 EDP44057.1 - 0.016 14.9 0.3 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain Septin PF00735.13 EDP44057.1 - 0.018 14.0 2.3 3 6.7 0.0 2.9 3 0 0 3 3 3 0 Septin NB-ARC PF00931.17 EDP44057.1 - 0.018 13.8 0.0 4.5 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 EDP44057.1 - 0.022 13.6 0.0 4.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EDP44057.1 - 0.029 13.8 0.8 5.4 6.4 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EDP44057.1 - 0.029 13.8 0.0 3.4 7.0 0.0 2.7 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 EDP44057.1 - 0.034 13.4 4.1 1.9 7.7 0.0 3.4 3 1 1 4 4 4 0 Poxvirus A32 protein Sigma54_activat PF00158.21 EDP44057.1 - 0.11 11.9 0.7 5.8 6.3 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain MRP-L27 PF09809.4 EDP44058.1 - 3.8e-05 23.2 0.4 0.0031 17.1 0.3 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 LRR_4 PF12799.2 EDP44060.1 - 2.6e-33 113.0 22.6 1.3e-09 37.4 1.5 5.7 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP44060.1 - 1.3e-27 95.2 55.4 1.7e-08 34.0 2.5 5.1 2 1 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EDP44060.1 - 7.2e-13 46.6 26.7 0.081 12.9 0.1 8.8 9 1 0 9 9 9 6 Leucine Rich Repeat LRR_9 PF14580.1 EDP44060.1 - 1.2e-11 44.5 6.5 1.4e-08 34.4 0.9 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 EDP44060.1 - 2.5e-11 41.8 19.0 0.65 10.4 0.0 9.0 9 1 0 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 EDP44060.1 - 2e-08 33.4 25.0 1.4 9.2 0.0 8.2 6 2 3 9 9 9 5 Leucine Rich repeat F_actin_cap_B PF01115.12 EDP44061.1 - 4.1e-20 72.0 0.3 4.9e-20 71.7 0.2 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Latarcin PF10279.4 EDP44061.1 - 0.033 14.3 1.4 0.042 14.0 0.9 1.3 1 0 0 1 1 1 0 Latarcin precursor UDPGP PF01704.13 EDP44062.1 - 1.9e-153 510.9 0.1 1e-105 353.6 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.22 EDP44063.1 - 5e-41 138.3 5.1 4.5e-16 58.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MDM31_MDM32 PF08118.6 EDP44064.1 - 9.6e-115 383.8 2.5 1.8e-83 280.7 1.7 3.0 2 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4279 PF14106.1 EDP44064.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF2416 PF10315.4 EDP44065.1 - 4.7e-09 36.4 1.7 6.6e-09 35.9 1.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Snf7 PF03357.16 EDP44066.1 - 0.0016 17.8 3.8 0.0017 17.7 2.2 1.3 1 1 0 1 1 1 1 Snf7 ERM PF00769.14 EDP44067.1 - 0.12 11.9 37.0 0.13 11.8 22.6 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Abhydrolase_6 PF12697.2 EDP44068.1 - 2.1e-06 27.8 2.8 0.0081 16.0 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Chitin_synth_2 PF03142.10 EDP44069.1 - 2.8e-227 755.3 0.1 4.1e-227 754.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EDP44069.1 - 2.9e-77 260.2 0.0 3.2e-64 217.1 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 EDP44069.1 - 5.4e-19 67.7 0.0 1.7e-10 40.5 0.0 2.5 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EDP44069.1 - 2.7e-14 53.5 0.2 3.4e-11 43.3 0.0 3.6 4 0 0 4 4 4 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDP44069.1 - 9.7e-14 51.5 4.7 9.7e-14 51.5 3.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EDP44069.1 - 3.3e-13 49.1 0.1 5.6e-12 45.2 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EDP44069.1 - 2e-07 30.8 0.0 0.00037 20.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDP44069.1 - 0.00063 19.0 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 BPL_LplA_LipB PF03099.14 EDP44070.1 - 4e-15 55.9 0.0 6.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cnd3 PF12719.2 EDP44071.1 - 5.7e-63 212.6 5.8 5.7e-63 212.6 4.0 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EDP44071.1 - 7.9e-08 32.4 15.8 4e-05 23.8 1.0 5.7 4 2 1 6 6 6 3 HEAT repeats HEAT PF02985.17 EDP44071.1 - 7.3e-07 28.7 10.3 0.41 10.8 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EDP44071.1 - 0.0056 17.1 15.6 0.64 10.5 0.0 6.5 6 2 1 7 7 7 2 HEAT-like repeat Arm PF00514.18 EDP44071.1 - 0.036 13.9 0.1 22 5.0 0.0 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EDP44071.1 - 0.037 13.9 1.2 11 5.9 0.2 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 EDP44071.1 - 0.049 11.9 0.9 0.43 8.8 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.2 EDP44071.1 - 0.5 10.1 4.2 12 5.6 0.2 3.9 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 BRO1 PF03097.13 EDP44072.1 - 7.2e-100 334.3 0.2 7.2e-100 334.3 0.2 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDP44072.1 - 3.7e-60 203.3 2.4 5.6e-60 202.8 1.7 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV GPS PF01825.16 EDP44072.1 - 0.27 11.3 2.3 0.38 10.9 0.8 1.9 1 1 1 2 2 2 0 Latrophilin/CL-1-like GPS domain zf-RING_2 PF13639.1 EDP44073.1 - 3.9e-15 55.3 10.1 6.1e-15 54.7 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDP44073.1 - 5e-09 36.1 5.2 8.5e-09 35.4 3.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDP44073.1 - 1.4e-07 31.4 8.5 2.1e-07 30.8 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44073.1 - 4.2e-07 29.5 7.6 6.6e-07 28.9 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDP44073.1 - 7.2e-07 28.7 8.1 1.1e-06 28.1 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP44073.1 - 1.7e-06 27.5 6.1 3e-06 26.8 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDP44073.1 - 4.3e-05 23.2 3.6 8e-05 22.4 2.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EDP44073.1 - 0.053 13.5 2.5 0.1 12.6 1.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EDP44073.1 - 0.19 11.7 9.6 0.32 11.0 6.7 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 EDP44073.1 - 0.31 11.1 11.2 0.52 10.3 7.8 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EDP44073.1 - 0.66 9.6 7.2 1.2 8.7 5.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EDP44073.1 - 1.2 9.0 6.7 5.2 7.0 4.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EDP44073.1 - 2.2 8.3 6.6 5 7.1 4.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RNase_P_Rpp14 PF01900.14 EDP44076.1 - 1.6e-22 79.4 0.0 2.9e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 Rpp14/Pop5 family SH3_2 PF07653.12 EDP44077.1 - 0.0098 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDP44077.1 - 0.013 14.8 0.1 0.92 8.9 0.2 2.3 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.1 EDP44077.1 - 0.014 14.9 0.1 0.065 12.8 0.1 2.0 1 1 0 1 1 1 0 Variant SH3 domain cobW PF02492.14 EDP44078.1 - 4.7e-47 159.7 0.3 2.5e-46 157.3 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 EDP44078.1 - 2.6e-24 85.5 0.0 5.6e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 HIT domain CobW_C PF07683.9 EDP44078.1 - 2.1e-21 75.4 0.1 6.7e-16 57.7 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 EDP44078.1 - 3.4e-06 27.2 0.0 8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding T2SE PF00437.15 EDP44078.1 - 0.023 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EDP44078.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EDP44078.1 - 0.072 12.7 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EDP44078.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EDP44078.1 - 0.11 12.0 0.1 0.32 10.5 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDP44078.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EDP44078.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EDP44078.1 - 0.21 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EDP44078.1 - 0.51 10.6 2.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TFIIB PF00382.14 EDP44079.1 - 1.8e-33 114.1 0.2 7.4e-18 64.1 0.0 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EDP44079.1 - 4.3e-27 94.1 0.9 4.3e-27 94.1 0.6 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EDP44079.1 - 2.7e-08 32.9 0.2 2.7e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 EDP44079.1 - 0.00068 19.2 0.1 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 EDP44079.1 - 0.0056 15.8 0.3 0.011 14.9 0.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Calc_CGRP_IAPP PF00214.14 EDP44079.1 - 0.053 13.5 0.8 0.16 11.9 0.5 1.8 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family HisG PF01634.13 EDP44080.1 - 6.4e-49 165.6 0.0 9.6e-49 165.0 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EDP44080.1 - 3e-26 91.1 0.0 5.1e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EDP44080.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 1 0 1 1 1 0 NMT1/THI5 like PAR1 PF06521.6 EDP44080.1 - 0.027 14.0 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 PAR1 protein SBP_bac_3 PF00497.15 EDP44080.1 - 0.15 11.3 0.0 0.41 9.8 0.0 1.8 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 AAA PF00004.24 EDP44081.1 - 4.9e-22 78.5 0.0 8.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Proteasome PF00227.21 EDP44082.1 - 5.1e-40 136.7 0.0 5.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cation_efflux PF01545.16 EDP44083.1 - 3.7e-12 45.9 2.6 4.6e-12 45.6 1.1 1.5 1 1 0 2 2 2 1 Cation efflux family DNA_pol_delta_4 PF04081.8 EDP44084.1 - 6.6e-22 78.1 0.0 8.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Antiterm PF03589.8 EDP44084.1 - 0.12 12.4 0.9 0.19 11.8 0.6 1.3 1 0 0 1 1 1 0 Antitermination protein Herpes_UL36 PF03586.8 EDP44084.1 - 0.38 9.7 2.5 0.55 9.2 1.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Met_10 PF02475.11 EDP44085.1 - 2.2e-58 197.1 0.0 3e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein zf-RING-like PF08746.6 EDP44085.1 - 0.0015 18.4 2.7 0.25 11.3 0.2 2.6 2 0 0 2 2 2 2 RING-like domain Bromodomain PF00439.20 EDP44086.1 - 4.1e-22 77.8 0.0 9.1e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acyltransferase PF01553.16 EDP44087.1 - 2.3e-20 72.3 0.0 3.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Cro PF09048.5 EDP44087.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cro zf-Tim10_DDP PF02953.10 EDP44088.1 - 1.7e-18 65.6 2.1 2.2e-18 65.2 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HPIP PF15226.1 EDP44088.1 - 0.015 15.2 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Cytomega_TRL10 PF06084.6 EDP44088.1 - 0.015 15.0 1.3 0.018 14.8 0.6 1.4 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein Pil1 PF13805.1 EDP44089.1 - 9.9e-09 34.7 1.0 9.9e-09 34.7 0.7 3.1 3 0 0 3 3 3 1 Eisosome component PIL1 Dicty_REP PF05086.7 EDP44089.1 - 0.43 8.2 1.5 0.72 7.5 1.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MRG PF05712.8 EDP44090.1 - 1.2e-56 190.7 0.0 1.8e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 MRG SR-25 PF10500.4 EDP44090.1 - 6.3 6.2 21.8 5.6 6.3 7.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Gly-zipper_OmpA PF13436.1 EDP44090.1 - 7.8 6.1 19.8 31 4.2 13.7 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain BAR_2 PF10455.4 EDP44091.1 - 9.1e-46 156.0 0.1 1.4e-45 155.4 0.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDP44091.1 - 1.1e-17 64.3 1.8 2.2e-11 43.7 0.1 2.1 2 0 0 2 2 2 2 BAR domain KapB PF08810.5 EDP44091.1 - 0.00024 21.1 3.5 0.033 14.2 0.2 2.5 2 0 0 2 2 2 2 Kinase associated protein B GAS PF13851.1 EDP44091.1 - 0.0023 17.1 5.5 0.0085 15.3 0.1 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Allexi_40kDa PF05549.6 EDP44091.1 - 0.016 14.5 5.0 0.016 14.4 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.17 EDP44091.1 - 0.019 14.9 0.9 0.22 11.5 0.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.16 EDP44091.1 - 0.028 14.3 1.5 0.056 13.4 0.1 2.2 3 0 0 3 3 2 0 bZIP transcription factor Med4 PF10018.4 EDP44091.1 - 0.039 13.3 0.3 0.039 13.3 0.2 2.3 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Uds1 PF15456.1 EDP44091.1 - 0.046 13.7 6.2 0.94 9.4 0.1 2.7 3 0 0 3 3 2 0 Up-regulated During Septation DUF3199 PF11436.3 EDP44091.1 - 0.056 13.2 0.3 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) STAT_alpha PF01017.15 EDP44091.1 - 0.1 12.2 5.0 0.7 9.5 0.1 2.6 2 1 0 2 2 2 0 STAT protein, all-alpha domain APG6 PF04111.7 EDP44091.1 - 0.12 11.3 6.5 0.96 8.4 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EDP44091.1 - 0.18 11.6 6.1 0.84 9.4 0.1 2.6 2 1 0 2 2 2 0 Tropomyosin like T2SG PF08334.6 EDP44091.1 - 0.22 11.3 1.7 0.77 9.5 0.1 2.6 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein G Fez1 PF06818.10 EDP44091.1 - 0.29 11.1 6.4 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Fez1 ATG16 PF08614.6 EDP44091.1 - 0.3 10.8 5.4 0.39 10.5 0.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EDP44091.1 - 0.33 10.5 7.3 0.71 9.4 0.1 2.2 2 0 0 2 2 2 0 IncA protein Acyl-CoA_dh_C PF12806.2 EDP44091.1 - 0.42 10.4 4.3 3 7.7 0.1 3.2 2 2 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Sec8_exocyst PF04048.9 EDP44091.1 - 0.65 9.6 4.9 0.25 10.9 0.2 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain HSCB_C PF07743.8 EDP44091.1 - 0.98 9.9 6.6 3.6 8.1 0.3 3.4 2 2 2 4 4 4 0 HSCB C-terminal oligomerisation domain CENP-F_leu_zip PF10473.4 EDP44091.1 - 1 9.1 7.6 3.7 7.3 0.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2383 PF09537.5 EDP44091.1 - 1.3 9.3 5.9 12 6.1 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF2383) TMF_TATA_bd PF12325.3 EDP44091.1 - 3.5 7.3 7.6 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CPSase_L_D2 PF02786.12 EDP44092.1 - 3.6e-112 372.7 0.1 3.8e-83 277.9 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 EDP44092.1 - 3.5e-44 149.8 0.0 8.8e-44 148.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 EDP44092.1 - 1.3e-42 145.4 0.0 3.3e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EDP44092.1 - 6e-42 142.2 0.0 1.2e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EDP44092.1 - 1.8e-37 128.8 0.3 5e-22 78.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EDP44092.1 - 2e-35 122.0 0.0 3.7e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_chain PF00289.17 EDP44092.1 - 2e-34 117.9 0.0 8.9e-17 61.1 0.0 3.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_sm_chain PF00988.17 EDP44092.1 - 1.3e-31 108.8 0.0 3.1e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain ATPgrasp_Ter PF15632.1 EDP44092.1 - 5.4e-23 81.2 0.0 3e-12 45.9 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDP44092.1 - 2.1e-16 59.9 0.0 2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDP44092.1 - 4.4e-15 55.4 0.0 2.2e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EDP44092.1 - 1.3e-13 50.6 0.0 6e-13 48.5 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain ATP-grasp_3 PF02655.9 EDP44092.1 - 3.2e-07 30.3 0.1 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EDP44092.1 - 4.4e-05 23.0 0.5 0.0014 18.1 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EDP44092.1 - 0.0033 16.9 0.0 1.2 8.5 0.0 2.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CBFD_NFYB_HMF PF00808.18 EDP44093.1 - 2e-17 62.9 0.3 3.1e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP44093.1 - 2.2e-07 30.9 0.3 3.2e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 EDP44093.1 - 0.067 12.9 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CMS1 PF14617.1 EDP44094.1 - 2.6e-28 98.7 0.0 1.2e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EDP44094.1 - 0.046 13.2 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1708 PF08101.6 EDP44096.1 - 1.8e-17 63.3 0.7 7.9e-17 61.1 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EDP44096.1 - 0.00075 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain zf-CSL PF05207.8 EDP44097.1 - 5.4e-24 83.4 1.2 7.7e-24 82.9 0.9 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EDP44097.1 - 0.022 14.3 0.3 0.033 13.7 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDP44097.1 - 0.045 13.4 0.3 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 EDP44097.1 - 0.096 12.2 3.7 0.1 12.2 1.2 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 EDP44097.1 - 0.11 12.5 1.6 0.15 12.0 0.3 1.8 2 0 0 2 2 2 0 Zinc ribbon domain RRM_6 PF14259.1 EDP44098.1 - 1.8e-07 31.0 0.0 6.7e-07 29.2 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP44098.1 - 6.8e-05 22.4 0.0 0.00043 19.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44098.1 - 0.00034 20.3 0.1 0.0033 17.2 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 EDP44098.1 - 0.061 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) DUF883 PF05957.8 EDP44098.1 - 0.85 10.0 3.9 3.2 8.1 2.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Rad60-SLD PF11976.3 EDP44099.1 - 6.9e-21 73.7 0.8 7.1e-18 64.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDP44099.1 - 3.2e-08 32.8 0.1 1.2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF4115 PF13464.1 EDP44099.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4115) TPR_11 PF13414.1 EDP44100.1 - 2.5e-47 158.3 23.7 1.9e-19 69.0 0.2 6.4 3 3 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EDP44100.1 - 6.7e-37 123.6 17.3 3.4e-06 26.4 0.1 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44100.1 - 2.6e-32 108.1 21.4 0.00011 21.7 0.0 11.0 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44100.1 - 1.4e-24 86.1 21.7 1.7e-05 25.3 0.0 7.0 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44100.1 - 3.2e-23 81.4 21.7 0.00031 20.6 0.1 7.5 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44100.1 - 1.4e-18 65.2 13.1 0.002 17.7 0.0 10.3 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44100.1 - 3e-16 58.2 7.9 0.019 15.1 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44100.1 - 3.6e-12 45.7 17.1 0.081 13.5 0.2 10.2 4 4 7 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44100.1 - 3.1e-09 37.0 17.4 0.015 15.6 0.2 7.3 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44100.1 - 1.6e-07 30.6 12.4 1.5 8.8 0.0 8.4 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44100.1 - 3.7e-05 23.5 12.4 0.00051 19.8 0.1 5.3 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDP44100.1 - 0.0085 15.1 12.6 0.23 10.4 0.5 4.6 3 1 1 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.7 EDP44100.1 - 0.016 15.8 3.4 13 6.5 0.1 4.0 3 0 0 3 3 3 0 Sel1 repeat SHNi-TPR PF10516.4 EDP44100.1 - 0.016 14.4 4.2 13 5.0 0.1 5.1 5 0 0 5 5 5 0 SHNi-TPR Glyco_hyd_65N_2 PF14498.1 EDP44100.1 - 0.072 12.7 0.9 5.6 6.5 0.0 3.4 3 1 1 4 4 4 0 Glycosyl hydrolase family 65, N-terminal domain TPR_6 PF13174.1 EDP44100.1 - 1.1 9.8 16.9 2e+02 2.8 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat CRAL_TRIO PF00650.15 EDP44101.1 - 1.2e-24 86.5 0.0 1.8e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDP44101.1 - 3.4e-05 23.8 1.9 0.0003 20.8 0.9 2.7 2 1 1 3 3 3 1 CRAL/TRIO, N-terminal domain ORC6 PF05460.8 EDP44101.1 - 0.0055 15.8 0.7 0.0075 15.4 0.5 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EOS1 PF12326.3 EDP44102.1 - 9.6e-22 77.2 0.3 2.6e-21 75.8 0.2 1.8 1 1 0 1 1 1 1 N-glycosylation protein Mago_nashi PF02792.9 EDP44103.1 - 3.1e-17 62.5 0.4 3.5e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Mago nashi protein Cpn10 PF00166.16 EDP44104.1 - 8e-11 41.7 0.0 8.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 EDP44105.1 - 5e-123 411.2 3.1 5.8e-123 411.0 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mito_carr PF00153.22 EDP44106.1 - 1.6e-71 236.0 0.5 2.4e-24 84.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4538 PF15061.1 EDP44106.1 - 0.19 11.0 1.0 0.48 9.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) CytB6-F_Fe-S PF08802.5 EDP44106.1 - 8.1 6.5 6.1 16 5.6 0.8 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit SMC_N PF02463.14 EDP44107.1 - 1.2e-25 90.1 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP44107.1 - 1.4e-06 28.4 0.3 2.2e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDP44107.1 - 0.17 12.1 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SMC_N PF02463.14 EDP44108.1 - 3.2e-41 140.9 0.2 7e-41 139.8 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDP44108.1 - 8.7e-16 58.8 5.5 8.7e-16 58.8 3.8 3.8 2 2 0 2 2 2 1 AAA domain SMC_hinge PF06470.8 EDP44108.1 - 1.6e-13 50.7 0.0 6.3e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDP44108.1 - 1.8e-06 28.1 0.2 2.8e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDP44108.1 - 1.8e-05 24.2 0.0 5.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EDP44108.1 - 5.2e-05 22.4 0.1 7.3e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2594 PF10769.4 EDP44108.1 - 0.02 14.9 3.5 0.052 13.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) Reo_sigmaC PF04582.7 EDP44108.1 - 0.12 11.5 23.2 0.11 11.7 2.5 4.2 2 2 2 4 4 4 0 Reovirus sigma C capsid protein DNA_ligase_A_N PF04675.9 EDP44109.1 - 9.1e-53 178.6 0.4 1.5e-52 178.0 0.3 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDP44109.1 - 5.4e-25 87.6 0.0 1.9e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.16 EDP44109.1 - 8.9e-23 80.7 0.0 1.5e-20 73.4 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 EDP44109.1 - 0.014 15.0 0.3 3 7.6 0.0 3.0 3 0 0 3 3 3 0 DNA ligase OB-like domain Peptidase_M48 PF01435.13 EDP44110.1 - 7.5e-28 97.6 0.7 1.9e-27 96.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 DUF4491 PF14898.1 EDP44110.1 - 0.029 14.5 0.5 0.16 12.1 0.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Peptidase_M13 PF01431.16 EDP44110.1 - 0.029 13.5 0.2 0.055 12.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M13 DUF2268 PF10026.4 EDP44110.1 - 0.046 13.1 0.2 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M57 PF12388.3 EDP44110.1 - 0.06 12.6 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M48 PF01435.13 EDP44111.1 - 5.5e-17 62.0 0.1 1e-16 61.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M48 GTP_EFTU PF00009.22 EDP44112.1 - 8.1e-57 191.6 0.2 2.4e-56 190.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDP44112.1 - 3e-37 126.8 0.0 6.3e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EDP44112.1 - 2.7e-30 104.0 0.0 6.2e-30 102.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDP44112.1 - 2.2e-23 81.9 0.1 5.3e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDP44112.1 - 5.4e-13 48.8 0.0 1.9e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TFIID-18kDa PF02269.11 EDP44113.1 - 6.1e-14 51.6 0.1 2.6e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit Nnf1 PF03980.9 EDP44114.1 - 0.016 15.2 4.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 0 Nnf1 TPR_MLP1_2 PF07926.7 EDP44114.1 - 0.13 12.0 6.6 2.1 8.1 0.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EDP44114.1 - 0.59 9.3 5.1 0.27 10.4 1.0 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 EDP44114.1 - 4.8 7.2 7.5 17 5.4 5.1 2.1 1 1 0 1 1 1 0 DivIVA protein PLA2_B PF01735.13 EDP44115.1 - 5.3e-17 61.1 0.0 6.1e-09 34.5 0.1 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Ribosomal_S10 PF00338.17 EDP44116.1 - 1.7e-18 66.2 0.0 2.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e BTB_2 PF02214.17 EDP44118.1 - 3.3e-05 24.0 0.0 0.00091 19.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Synaptobrevin PF00957.16 EDP44119.1 - 4.8e-08 32.4 7.0 5.3e-05 22.7 0.1 3.1 2 1 1 3 3 3 2 Synaptobrevin DUF816 PF05674.7 EDP44119.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) DUF1664 PF07889.7 EDP44119.1 - 0.14 11.9 0.4 0.24 11.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Septin PF00735.13 EDP44120.1 - 3.6e-103 344.4 0.1 4.8e-103 344.0 0.1 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EDP44120.1 - 0.011 15.1 0.0 0.19 11.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-met PF12874.2 EDP44121.1 - 3.9e-06 26.8 0.8 3.9e-06 26.8 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Pyr_redox_3 PF13738.1 EDP44122.1 - 7.5e-07 29.4 0.0 0.024 14.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDP44122.1 - 2.1e-05 24.3 0.1 0.0032 17.2 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDP44122.1 - 0.00063 19.6 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP44122.1 - 0.0019 18.1 0.0 0.0062 16.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDP44122.1 - 0.0087 15.0 0.2 3.1 6.6 0.2 2.9 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EDP44122.1 - 0.015 15.6 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP44122.1 - 0.064 11.7 0.1 0.85 8.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein UPF0172 PF03665.8 EDP44123.1 - 1.1e-36 126.1 0.7 2.9e-36 124.8 0.5 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EDP44123.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ras PF00071.17 EDP44124.1 - 5.7e-55 185.1 0.0 6.8e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP44124.1 - 7.4e-17 61.9 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP44124.1 - 9.2e-15 54.3 0.0 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDP44124.1 - 1e-05 25.4 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDP44124.1 - 0.00013 21.1 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDP44124.1 - 0.00037 19.9 0.0 0.00064 19.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EDP44124.1 - 0.0021 18.0 0.0 0.0089 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDP44124.1 - 0.0039 17.3 0.0 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDP44124.1 - 0.0085 15.2 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EDP44124.1 - 0.021 14.0 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.8 EDP44124.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EDP44124.1 - 0.034 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDP44124.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDP44124.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TruD PF01142.13 EDP44125.1 - 3e-57 194.0 0.0 1.5e-55 188.3 0.0 2.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) SR-25 PF10500.4 EDP44125.1 - 8.9 5.7 13.6 20 4.5 9.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ammonium_transp PF00909.16 EDP44126.1 - 2.1e-105 352.5 24.1 2.4e-105 352.2 16.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2149 PF09919.4 EDP44126.1 - 7.3 6.7 5.4 27 4.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) ENTH PF01417.15 EDP44127.1 - 1.3e-46 157.4 0.3 2.4e-46 156.6 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EDP44127.1 - 7e-05 21.6 0.9 0.00013 20.7 0.4 1.6 1 1 0 1 1 1 1 ANTH domain GlyL_C PF12524.3 EDP44127.1 - 0.14 12.0 7.3 0.08 12.8 2.5 2.4 1 1 1 2 2 2 0 dsDNA virus glycoprotein L C terminal PAT1 PF09770.4 EDP44127.1 - 3.8 5.6 37.1 5.1 5.2 25.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Na_Ca_ex PF01699.19 EDP44128.1 - 1.3e-27 96.0 26.2 1.5e-17 63.4 6.0 2.9 2 1 0 2 2 2 2 Sodium/calcium exchanger protein MatE PF01554.13 EDP44128.1 - 0.0076 15.8 0.7 0.0076 15.8 0.5 2.8 2 1 1 3 3 3 1 MatE Pkinase PF00069.20 EDP44129.1 - 5.5e-73 245.3 0.0 8.1e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44129.1 - 5.6e-34 117.3 0.0 8.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44129.1 - 3.8e-07 29.3 0.0 8.7e-07 28.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP44129.1 - 0.049 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.23 EDP44130.1 - 5.2e-06 25.8 2.1 0.00055 19.4 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDP44130.1 - 1e-05 25.0 10.2 0.00054 19.5 0.4 4.6 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EDP44130.1 - 5.7e-05 22.7 16.7 0.00016 21.3 0.2 6.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44130.1 - 0.00018 22.0 5.4 0.00018 22.0 3.7 6.3 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44130.1 - 0.00066 19.2 0.0 0.69 9.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44130.1 - 0.0008 19.4 0.4 7.5 7.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44130.1 - 0.011 15.6 2.1 0.011 15.6 1.4 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44130.1 - 0.031 14.9 0.7 0.031 14.9 0.5 8.9 9 1 2 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44130.1 - 0.48 10.3 4.0 32 4.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Tubulin PF00091.20 EDP44131.1 - 6e-72 241.9 0.0 1.2e-71 241.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDP44131.1 - 1.7e-47 160.5 0.8 2.7e-47 159.9 0.5 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDP44131.1 - 7.7e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EDP44131.1 - 0.00054 19.4 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Saccharop_dh PF03435.13 EDP44132.1 - 1.1e-102 343.8 0.0 2e-102 343.0 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EDP44132.1 - 2.2e-90 301.9 0.0 6.5e-90 300.3 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 EDP44132.1 - 6.3e-06 26.4 0.4 3.4e-05 24.1 0.1 2.3 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDP44132.1 - 0.0015 18.6 0.0 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EDP44132.1 - 0.0043 16.5 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDP44132.1 - 0.0094 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDP44132.1 - 0.012 15.6 0.1 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_12 PF08242.7 EDP44132.1 - 0.02 15.3 0.2 1.6 9.2 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain NmrA PF05368.8 EDP44132.1 - 0.058 12.6 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family Methyltransf_18 PF12847.2 EDP44132.1 - 0.11 13.0 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF2325 PF10087.4 EDP44132.1 - 0.28 11.0 0.9 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) CENP-B_dimeris PF09026.5 EDP44133.1 - 0.0012 19.0 4.6 0.0028 17.8 3.2 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Daxx PF03344.10 EDP44133.1 - 0.95 7.8 12.2 1.2 7.5 8.4 1.1 1 0 0 1 1 1 0 Daxx Family NPR3 PF03666.8 EDP44133.1 - 1.8 6.9 6.5 2.6 6.5 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.12 EDP44133.1 - 3.1 6.5 4.9 3.7 6.2 3.4 1.1 1 0 0 1 1 1 0 Presenilin Ank PF00023.25 EDP44134.1 - 9.8e-31 104.0 10.5 1.6e-10 40.2 0.0 5.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 EDP44134.1 - 7.8e-29 99.8 0.1 8.5e-18 64.4 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDP44134.1 - 8.8e-26 87.4 1.4 2.7e-07 30.1 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EDP44134.1 - 5.8e-24 84.0 6.6 2.8e-11 43.5 0.2 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDP44134.1 - 1.2e-23 82.6 8.8 2.3e-09 37.1 0.2 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Prenyltrans PF00432.16 EDP44135.1 - 3.6e-32 109.6 6.9 1.7e-09 37.0 0.1 7.2 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDP44135.1 - 5.7e-26 91.1 1.0 2.1e-16 60.3 0.0 5.0 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDP44135.1 - 7.6e-25 87.0 0.3 7.6e-14 51.6 0.1 5.4 4 1 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 EDP44135.1 - 4.3e-08 32.6 0.4 0.0077 15.4 0.1 4.2 2 1 2 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 EDP44135.1 - 2.6e-05 23.6 0.0 0.0079 15.4 0.0 3.5 3 1 2 5 5 5 1 A-macroglobulin complement component Mago-bind PF09282.5 EDP44135.1 - 0.022 14.3 0.1 0.34 10.5 0.0 2.8 3 0 0 3 3 3 0 Mago binding Methyltransf_26 PF13659.1 EDP44136.1 - 8.1e-14 51.6 0.3 8.1e-14 51.6 0.2 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDP44136.1 - 9.7e-09 34.8 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EDP44136.1 - 2.2e-07 30.5 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP44136.1 - 4.6e-06 27.1 0.2 9.9e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EDP44136.1 - 2.6e-05 23.8 0.2 6.7e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EDP44136.1 - 0.00011 22.4 0.1 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EDP44136.1 - 0.00049 19.2 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_24 PF13578.1 EDP44136.1 - 0.0014 19.4 0.9 0.0014 19.4 0.6 1.9 2 1 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 EDP44136.1 - 0.0041 17.1 0.1 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain PrmA PF06325.8 EDP44136.1 - 0.0043 16.2 0.1 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EDP44136.1 - 0.0053 17.2 0.2 0.012 16.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP44136.1 - 0.0086 16.5 0.1 0.019 15.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 EDP44136.1 - 0.021 13.8 0.1 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eco57I PF07669.6 EDP44136.1 - 0.036 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase CheR PF01739.13 EDP44136.1 - 0.052 12.8 0.2 0.89 8.8 0.1 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain 3HCDH_N PF02737.13 EDP44136.1 - 0.065 12.8 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EDP44136.1 - 0.085 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase N6-adenineMlase PF10237.4 EDP44136.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Pex16 PF08610.5 EDP44137.1 - 4.8e-71 239.4 1.2 2e-58 198.0 0.1 2.1 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) ATG13 PF10033.4 EDP44138.1 - 8.5e-24 84.2 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Pkinase PF00069.20 EDP44139.1 - 3.3e-54 183.7 0.0 4e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44139.1 - 1.5e-36 125.7 0.0 5.9e-35 120.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44139.1 - 3.5e-07 29.4 0.0 1e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDP44139.1 - 0.025 14.3 0.0 0.37 10.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDP44139.1 - 0.079 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_transf_22 PF03901.12 EDP44140.1 - 1.9e-75 254.4 29.4 2e-75 254.3 20.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ERCC4 PF02732.10 EDP44141.1 - 4.1e-09 36.3 0.2 8.7e-09 35.2 0.1 1.6 2 0 0 2 2 2 1 ERCC4 domain NatB_MDM20 PF09797.4 EDP44142.1 - 1.9e-48 165.0 0.0 2.9e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit EGF_alliinase PF04863.8 EDP44142.1 - 0.096 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain Med14 PF08638.6 EDP44143.1 - 4.8e-41 140.1 0.0 1.1e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 HEAT PF02985.17 EDP44144.1 - 4.9e-06 26.1 1.9 0.26 11.4 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Pkinase PF00069.20 EDP44144.1 - 0.0094 15.1 0.0 0.19 10.8 0.0 2.7 2 1 1 3 3 3 1 Protein kinase domain HEAT_EZ PF13513.1 EDP44144.1 - 0.015 15.7 4.2 0.8 10.2 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.3 EDP44144.1 - 0.017 14.4 0.3 0.6 9.4 0.2 2.4 1 1 0 1 1 1 0 CLASP N terminal Katanin_con80 PF13925.1 EDP44144.1 - 0.028 14.1 0.4 0.69 9.6 0.1 2.3 1 1 1 2 2 2 0 con80 domain of Katanin HEAT_2 PF13646.1 EDP44144.1 - 0.14 12.4 3.7 0.36 11.1 0.3 2.9 2 1 1 3 3 3 0 HEAT repeats SIR2 PF02146.12 EDP44145.1 - 3.1e-19 69.3 1.9 8.3e-14 51.7 0.1 2.2 1 1 1 2 2 2 2 Sir2 family Mito_carr PF00153.22 EDP44146.1 - 6.6e-10 38.5 0.1 0.0043 16.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_LMP1 PF05297.6 EDP44146.1 - 0.056 12.3 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1218 PF06749.7 EDP44146.1 - 1.3 9.5 5.3 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Mito_carr PF00153.22 EDP44147.1 - 2.5e-12 46.3 0.0 2.3e-05 23.9 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein PRA1 PF03208.14 EDP44148.1 - 8.3e-16 57.6 8.0 9.7e-16 57.4 5.5 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF4029 PF13221.1 EDP44148.1 - 0.22 11.9 2.1 0.29 11.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) FA_desaturase PF00487.19 EDP44148.1 - 1.3 8.3 7.5 1.7 8.0 5.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Corona_M PF01635.13 EDP44148.1 - 2.5 6.9 7.2 4.2 6.2 0.2 2.0 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Telomerase_RBD PF12009.3 EDP44149.1 - 1.8e-30 105.6 0.5 3.6e-30 104.6 0.3 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EDP44149.1 - 4.6e-10 39.2 0.0 1.2e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 EDP44151.1 - 2.6e-87 283.8 21.1 6.9e-09 35.2 0.1 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EDP44151.1 - 6.7e-37 126.2 0.0 1.3e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EDP44151.1 - 2e-10 39.4 15.4 0.36 8.9 0.0 6.7 3 2 4 7 7 7 6 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP44151.1 - 8.8e-09 34.5 3.2 1.4 7.5 0.0 5.6 4 3 0 4 4 4 4 Nup133 N terminal like SF3b1 PF08920.5 EDP44152.1 - 1.5e-27 96.4 4.2 1.5e-27 96.3 0.4 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EDP44152.1 - 6.1e-19 68.0 14.7 3e-06 27.4 0.1 8.1 7 2 3 10 10 10 5 HEAT repeats HEAT PF02985.17 EDP44152.1 - 2.9e-12 45.5 13.0 0.066 13.3 0.0 11.1 11 0 0 11 11 11 1 HEAT repeat HEAT_EZ PF13513.1 EDP44152.1 - 1.4e-11 44.5 12.2 0.037 14.5 0.0 9.4 8 2 2 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 EDP44152.1 - 1.9e-08 33.0 2.1 0.057 11.7 0.2 3.9 2 1 2 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EDP44152.1 - 1.5e-05 25.3 1.9 4.4 7.7 0.0 5.6 7 0 0 7 7 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDP44152.1 - 2.3e-05 23.8 2.2 0.23 10.7 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal NUC173 PF08161.7 EDP44152.1 - 5e-05 22.7 0.9 5.9 6.1 0.0 4.9 4 1 1 5 5 5 1 NUC173 domain Arm PF00514.18 EDP44152.1 - 0.013 15.3 0.4 65 3.5 0.0 5.2 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EDP44152.1 - 0.029 13.9 0.2 0.35 10.4 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF4533 PF15047.1 EDP44152.1 - 0.16 11.3 0.0 0.42 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Dopey_N PF04118.9 EDP44152.1 - 0.2 10.3 0.1 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Dopey, N-terminal Tudor-knot PF11717.3 EDP44153.1 - 1.3e-19 69.6 0.3 2.3e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MOZ_SAS PF01853.13 EDP44154.1 - 3.4e-87 290.5 0.6 4.1e-87 290.3 0.4 1.0 1 0 0 1 1 1 1 MOZ/SAS family FR47 PF08445.5 EDP44154.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein HTH_11 PF08279.7 EDP44154.1 - 0.14 11.7 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain RRM_1 PF00076.17 EDP44155.1 - 8.3e-06 25.3 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44155.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44155.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S2 PF00318.15 EDP44156.1 - 5.6e-44 149.8 0.0 3.3e-22 78.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S5 PF00333.15 EDP44157.1 - 3.5e-27 93.9 1.4 6.1e-27 93.1 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDP44157.1 - 1.9e-20 71.9 0.0 3.3e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_L19e PF01280.15 EDP44157.1 - 1 9.1 3.4 2 8.2 2.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e F1F0-ATPsyn_F PF10791.4 EDP44158.1 - 6.1e-28 96.8 0.2 3.7e-27 94.3 0.0 2.1 2 1 0 2 2 2 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EDP44158.1 - 0.073 13.1 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f BRO1 PF03097.13 EDP44159.1 - 3.2e-07 29.4 0.1 4e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain IMS PF00817.15 EDP44160.1 - 1.1e-44 151.8 0.8 2.1e-44 150.9 0.5 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDP44160.1 - 6.5e-14 51.9 0.8 1.1e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EDP44160.1 - 0.00031 20.6 0.0 0.00082 19.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Peptidase_C54 PF03416.14 EDP44161.1 - 4.1e-80 268.8 0.0 2.9e-79 266.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EDP44161.1 - 0.043 12.9 0.2 0.16 11.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C78 NAP PF00956.13 EDP44162.1 - 5.9e-78 261.3 0.4 5.9e-78 261.3 0.3 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.7 EDP44162.1 - 0.22 11.8 1.9 0.51 10.6 0.3 2.1 2 0 0 2 2 2 0 Striatin family DUF4611 PF15387.1 EDP44162.1 - 1.9 8.6 22.0 1.8 8.7 1.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Vps53_N PF04100.7 EDP44163.1 - 5.3e-78 262.4 0.1 1.1e-77 261.4 0.1 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 EDP44163.1 - 3.1e-06 25.5 0.0 3.7e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec6 Trypan_PARP PF05887.6 EDP44164.1 - 1.8 8.3 5.5 0.32 10.8 1.3 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ETC_C1_NDUFA4 PF04800.7 EDP44165.1 - 1.1e-14 54.1 0.4 1.7e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region ATP_bind_1 PF03029.12 EDP44166.1 - 5.4e-36 124.3 0.0 6.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ATP_bind_1 PF03029.12 EDP44167.1 - 2.1e-05 24.1 0.1 2.2e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein HTH_Tnp_Mu_2 PF09039.6 EDP44167.1 - 0.0039 16.8 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Mu DNA binding, I gamma subdomain HSA PF07529.8 EDP44169.1 - 1.1e-18 66.7 4.1 1.1e-18 66.7 2.9 4.0 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EDP44169.1 - 0.0014 18.6 0.8 0.004 17.2 0.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PP2C_2 PF13672.1 EDP44170.1 - 1.6e-08 34.2 1.3 1.1e-07 31.4 0.9 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDP44170.1 - 7.2e-08 32.3 0.0 0.0051 16.5 0.0 2.9 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EDP44170.1 - 1e-07 31.5 0.1 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Isochorismatase PF00857.15 EDP44171.1 - 3.4e-17 62.9 2.0 1.1e-16 61.3 1.4 1.7 1 1 0 1 1 1 1 Isochorismatase family TRP_N PF14558.1 EDP44172.1 - 7.1e-21 74.7 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 ML-like domain TRP PF06011.7 EDP44172.1 - 5e-17 61.6 2.1 6.4e-17 61.2 1.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel KH_1 PF00013.24 EDP44173.1 - 8.6e-68 223.8 9.6 7.2e-12 44.7 0.0 10.7 11 1 0 11 11 11 7 KH domain KH_3 PF13014.1 EDP44173.1 - 7.3e-42 140.3 12.5 3e-09 36.3 0.0 9.0 9 0 0 9 9 9 6 KH domain KH_2 PF07650.12 EDP44173.1 - 9.8e-12 44.2 4.6 0.3 10.6 0.0 6.4 5 1 1 6 6 6 4 KH domain KH_4 PF13083.1 EDP44173.1 - 0.00012 21.6 6.8 4.3 7.0 0.0 5.6 7 0 0 7 7 7 2 KH domain KH_5 PF13184.1 EDP44173.1 - 0.00015 21.5 0.0 9.8 6.0 0.0 5.3 5 0 0 5 5 5 1 NusA-like KH domain ZU5 PF00791.15 EDP44173.1 - 0.018 14.6 0.0 0.79 9.4 0.0 3.2 3 0 0 3 3 3 0 ZU5 domain SelP_N PF04592.9 EDP44173.1 - 1.6 8.0 5.5 2.9 7.2 3.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.11 EDP44174.1 - 1.2e-19 70.2 42.8 3.2e-11 42.5 15.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EDP44175.1 - 1.6e-16 59.4 7.2 2e-07 30.5 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Hira PF07569.6 EDP44175.1 - 0.11 11.6 0.0 6 6.0 0.0 2.6 2 1 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.1 EDP44175.1 - 0.99 9.7 5.6 7.6 6.9 0.0 3.8 3 1 0 3 3 3 0 PQQ-like domain Metallophos PF00149.23 EDP44176.1 - 7.3e-12 45.1 1.5 5.2e-11 42.3 1.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 EDP44177.1 - 1.1e-10 41.2 3.5 2.1e-10 40.3 2.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDP44177.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF836 PF05768.9 EDP44179.1 - 1e-10 41.7 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) CPDase PF07823.6 EDP44179.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Thioredoxin_2 PF13098.1 EDP44179.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain SUR7 PF06687.7 EDP44180.1 - 1.6e-09 37.6 2.5 2.7e-09 36.8 1.7 1.3 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EDP44180.1 - 2.2e-06 27.5 1.3 2.2e-06 27.5 0.9 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 EDP44180.1 - 0.044 13.3 3.0 0.093 12.3 2.1 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NfeD PF01957.13 EDP44180.1 - 4.4 7.4 7.0 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding SelP_N PF04592.9 EDP44180.1 - 5.1 6.4 7.8 0.11 11.8 0.4 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region tRNA-synt_1 PF00133.17 EDP44181.1 - 7.7e-33 113.3 0.0 2.3e-24 85.3 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDP44181.1 - 5e-16 58.3 0.0 7.4e-09 34.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDP44181.1 - 1.6e-14 53.9 0.1 4.7e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDP44181.1 - 1.3e-06 27.7 0.0 2.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Med12 PF09497.5 EDP44182.1 - 1.2e-09 37.9 0.4 1.2e-09 37.9 0.3 2.5 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 SNF2_N PF00176.18 EDP44183.1 - 4.1e-65 219.5 0.1 6.2e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EDP44183.1 - 2.3e-18 65.5 2.9 2.6e-13 49.3 0.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EDP44183.1 - 8.8e-16 57.5 0.0 6.3e-15 54.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDP44183.1 - 2.3e-08 33.2 0.9 8.4e-08 31.3 0.2 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EDP44183.1 - 7.9e-05 22.5 0.0 0.0007 19.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDP44183.1 - 0.00052 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CRA_rpt PF07046.6 EDP44183.1 - 1.7 8.7 9.1 4.3 7.4 6.3 1.6 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat DUF4208 PF13907.1 EDP44184.1 - 1.9e-31 108.2 1.5 3.7e-31 107.3 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) DUF2422 PF10337.4 EDP44184.1 - 0.041 12.6 1.9 0.055 12.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Peptidase_M18 PF02127.10 EDP44184.1 - 0.06 11.8 0.2 0.13 10.7 0.0 1.5 2 0 0 2 2 2 0 Aminopeptidase I zinc metalloprotease (M18) RAP1 PF07218.6 EDP44184.1 - 2 6.4 4.8 2.4 6.1 3.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MMR_HSR1 PF01926.18 EDP44185.1 - 6.6e-17 61.5 0.1 7.5e-13 48.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP44185.1 - 4.4e-07 29.3 0.1 0.00012 21.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDP44185.1 - 2.3e-06 27.1 0.0 0.00034 20.1 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDP44185.1 - 0.00079 19.2 0.6 0.16 11.8 0.1 2.9 2 1 0 2 2 2 2 Dynamin family DUF258 PF03193.11 EDP44185.1 - 0.0017 17.5 0.1 0.004 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PALP PF00291.20 EDP44186.1 - 3.8e-75 252.9 2.2 4.8e-75 252.6 1.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EDP44186.1 - 1.4e-40 136.7 0.0 1.3e-23 82.3 0.0 3.5 3 0 0 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase Peripla_BP_6 PF13458.1 EDP44186.1 - 0.0022 17.4 0.3 0.0037 16.6 0.2 1.4 1 0 0 1 1 1 1 Periplasmic binding protein NQRA_SLBB PF11973.3 EDP44186.1 - 0.036 14.4 0.1 8.7 6.7 0.0 3.1 2 0 0 2 2 2 0 NQRA C-terminal domain ABC_membrane PF00664.18 EDP44187.1 - 2.5e-78 263.2 20.6 2.6e-40 138.5 3.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDP44187.1 - 2.1e-59 199.7 0.0 1.2e-28 100.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDP44187.1 - 1.4e-10 40.7 3.1 0.00024 20.4 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDP44187.1 - 4.1e-07 30.8 0.1 0.0045 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDP44187.1 - 1.6e-06 28.2 0.5 0.33 11.0 0.0 4.7 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.1 EDP44187.1 - 4.9e-06 25.9 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 EDP44187.1 - 6.9e-05 22.5 0.5 0.014 14.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EDP44187.1 - 0.00018 21.3 4.7 0.65 9.9 0.1 4.2 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EDP44187.1 - 0.00027 20.3 0.1 0.38 10.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 EDP44187.1 - 0.0005 18.7 0.2 0.032 12.8 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF87 PF01935.12 EDP44187.1 - 0.00083 19.2 0.1 0.93 9.2 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 EDP44187.1 - 0.0018 17.9 0.0 0.94 9.1 0.0 3.3 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EDP44187.1 - 0.0025 17.6 2.3 1.4 8.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EDP44187.1 - 0.003 17.8 0.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDP44187.1 - 0.0044 16.2 0.0 3.2 6.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 L_biotic_typeA PF04604.8 EDP44187.1 - 0.0074 15.9 0.3 4.6 6.9 0.0 2.7 2 0 0 2 2 2 1 Type-A lantibiotic AAA_21 PF13304.1 EDP44187.1 - 0.0088 16.0 0.0 26 4.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 EDP44187.1 - 0.0096 15.3 0.7 10 5.4 0.1 3.4 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EDP44187.1 - 0.028 13.9 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EDP44187.1 - 0.064 12.0 0.0 0.25 10.0 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 EDP44187.1 - 0.17 11.3 0.8 14 5.1 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AMP-binding PF00501.23 EDP44188.1 - 2.9e-77 259.8 0.1 4.9e-77 259.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EDP44188.1 - 5.2e-18 64.9 0.5 2.3e-14 52.9 0.5 2.7 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EDP44188.1 - 7.2e-06 26.1 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EDP44189.1 - 1.7e-72 244.1 0.2 8.7e-72 241.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EDP44189.1 - 0.00016 21.8 0.1 0.00043 20.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 EDP44190.1 - 3.2e-07 29.5 0.0 5.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Condensation PF00668.15 EDP44191.1 - 3.6e-51 173.7 2.8 1.3e-24 86.6 0.0 2.4 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.23 EDP44191.1 - 1.2e-50 172.2 0.1 2.2e-50 171.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EDP44191.1 - 3.3e-16 59.3 1.3 1.7e-08 34.6 0.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDP44191.1 - 1.5e-05 25.8 0.1 6.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DEAD PF00270.24 EDP44192.1 - 3.4e-39 134.0 0.0 7.9e-39 132.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP44192.1 - 1.9e-20 72.5 0.0 7.9e-20 70.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EDP44192.1 - 7.1e-17 60.9 0.0 2.5e-16 59.2 0.1 2.0 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 EDP44192.1 - 0.0012 18.7 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RecO_C PF02565.10 EDP44193.1 - 0.031 14.1 0.1 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Recombination protein O C terminal PPR_2 PF13041.1 EDP44193.1 - 0.059 13.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family Metallophos PF00149.23 EDP44194.1 - 4.3e-40 137.2 1.5 5.5e-40 136.9 1.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDP44194.1 - 0.0028 17.4 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Put_Phosphatase PF06888.7 EDP44195.1 - 8.3e-40 136.4 0.0 5.2e-27 94.5 0.0 2.0 1 1 1 2 2 2 2 Putative Phosphatase HAD PF12710.2 EDP44195.1 - 0.16 12.1 0.5 1.4 9.0 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase RhoGEF PF00621.15 EDP44196.1 - 9.4e-18 64.7 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LysM PF01476.15 EDP44197.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain DUF1168 PF06658.7 EDP44198.1 - 5.1e-32 110.3 12.0 5.1e-32 110.3 8.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) VSG_B PF13206.1 EDP44198.1 - 0.12 11.4 5.3 0.18 10.9 3.7 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain MmgE_PrpD PF03972.9 EDP44199.1 - 3.5e-156 519.8 0.3 4.1e-156 519.6 0.2 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.20 EDP44200.1 - 4.3e-60 203.5 0.2 5.3e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pkinase PF00069.20 EDP44201.1 - 1e-54 185.4 0.0 1.7e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44201.1 - 2.9e-21 75.7 0.0 4.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP44201.1 - 0.006 16.3 0.2 0.006 16.3 0.1 3.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDP44201.1 - 0.034 13.4 0.3 0.069 12.4 0.2 1.5 1 0 0 1 1 1 0 RIO1 family NUDE_C PF04880.8 EDP44202.1 - 2.2e-14 54.1 14.1 2.2e-14 54.1 9.7 3.3 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EDP44202.1 - 0.00011 22.3 27.7 0.0022 18.2 4.6 4.3 3 1 1 4 4 4 3 Protein of unknown function (DUF904) DUF972 PF06156.8 EDP44202.1 - 0.0091 16.3 19.3 0.097 13.0 0.9 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF972) Flg_hook PF02120.11 EDP44202.1 - 0.029 14.0 0.9 0.029 14.0 0.6 3.1 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK ERM PF00769.14 EDP44202.1 - 0.1 12.0 33.2 0.048 13.1 12.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_1 PF00170.16 EDP44202.1 - 0.16 11.9 0.1 0.16 11.9 0.1 4.4 4 1 2 6 6 5 0 bZIP transcription factor Tox-PLDMTX PF15645.1 EDP44202.1 - 0.22 11.5 1.5 0.39 10.7 0.3 2.0 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold HALZ PF02183.13 EDP44202.1 - 0.33 10.6 0.1 0.33 10.6 0.0 3.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Sec2p PF06428.6 EDP44202.1 - 0.49 10.2 18.7 1.3 8.9 6.3 3.3 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p CENP-K PF11802.3 EDP44202.1 - 0.71 9.0 12.1 8.6 5.5 8.4 2.0 1 1 0 1 1 1 0 Centromere-associated protein K GAS PF13851.1 EDP44202.1 - 1.1 8.3 28.7 0.017 14.2 9.5 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EDP44202.1 - 1.3 8.8 27.2 0.28 11.0 3.9 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EDP44202.1 - 1.5 8.7 8.1 3.4 7.6 0.0 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EDP44202.1 - 3.8 7.2 30.7 0.23 11.1 3.3 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4071 PF13281.1 EDP44202.1 - 4.8 5.9 15.4 2.9 6.6 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) Filament PF00038.16 EDP44202.1 - 5.2 6.4 29.6 0.18 11.2 5.0 3.3 2 1 2 4 4 4 0 Intermediate filament protein Fib_alpha PF08702.5 EDP44202.1 - 6.5 6.8 14.2 0.12 12.4 1.8 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CAP_GLY PF01302.20 EDP44203.1 - 3.8e-15 55.3 0.2 5.6e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF3138 PF11336.3 EDP44203.1 - 8.1 4.4 9.9 0.56 8.3 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) GN3L_Grn1 PF08701.6 EDP44204.1 - 2.5e-24 84.9 13.4 2.5e-24 84.9 9.3 3.4 4 0 0 4 4 4 1 GNL3L/Grn1 putative GTPase Nop14 PF04147.7 EDP44204.1 - 2.1e-05 22.6 24.1 2.1e-05 22.6 16.7 2.9 2 1 1 3 3 3 1 Nop14-like family CENP-T PF15511.1 EDP44204.1 - 0.0014 17.9 16.5 0.0014 17.9 11.4 3.3 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T CDC45 PF02724.9 EDP44204.1 - 0.083 10.9 36.3 0.076 11.0 15.1 3.2 3 0 0 3 3 3 0 CDC45-like protein CbiA PF01656.18 EDP44204.1 - 0.099 12.0 0.1 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Proteasome PF00227.21 EDP44205.1 - 3.4e-36 124.3 0.0 3.7e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 EDP44206.1 - 2.4e-08 32.6 1.2 3.4e-08 32.2 0.9 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDP44206.1 - 3.3e-06 27.1 0.1 4.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EDP44206.1 - 5.7e-06 25.4 0.5 9.3e-06 24.7 0.3 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EDP44206.1 - 0.00049 19.6 1.2 0.00095 18.7 0.9 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDP44206.1 - 0.00054 19.6 0.4 0.00082 19.0 0.2 1.5 1 1 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.2 EDP44206.1 - 0.086 12.5 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Ribosomal_S13 PF00416.17 EDP44207.1 - 2.9e-22 79.1 0.0 3.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDP44207.1 - 0.00013 20.6 0.0 0.0002 20.0 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Pkinase PF00069.20 EDP44208.1 - 9.9e-31 106.8 0.0 6.5e-28 97.5 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44208.1 - 3e-20 72.3 0.0 3.7e-19 68.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44208.1 - 7e-05 21.9 0.0 0.00022 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like AMP-binding PF00501.23 EDP44209.1 - 1.5e-51 175.1 0.0 2.9e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Gar1 PF04410.9 EDP44210.1 - 3.8e-41 140.1 1.9 6.9e-41 139.2 1.3 1.5 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Vps26 PF03643.10 EDP44211.1 - 5e-129 428.9 1.8 5.7e-129 428.7 1.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EDP44211.1 - 0.0022 17.8 0.1 0.5 10.1 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.7 EDP44211.1 - 0.0065 15.0 0.3 0.01 14.4 0.0 1.4 2 0 0 2 2 2 1 Bul1 N terminus ATG27 PF09451.5 EDP44212.1 - 6.3e-40 137.1 0.0 1.2e-39 136.1 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF2633 PF11119.3 EDP44212.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) WD40 PF00400.27 EDP44213.1 - 3e-25 87.1 8.9 7.4e-07 28.8 0.2 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 EDP44213.1 - 1.6e-22 79.9 0.0 6.3e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDP44213.1 - 1.9e-10 40.4 0.1 3.8e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RNA_pol_Rpc34 PF05158.7 EDP44214.1 - 3.1e-67 227.1 0.0 4.7e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR PF01047.17 EDP44214.1 - 0.013 15.1 0.2 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 MarR family HxlR PF01638.12 EDP44214.1 - 0.025 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix RPA_C PF08784.6 EDP44214.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Replication protein A C terminal Rrf2 PF02082.15 EDP44214.1 - 0.12 12.4 0.2 0.44 10.7 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator MIP-T3 PF10243.4 EDP44214.1 - 1.8 6.9 38.9 2.8 6.3 26.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Topoisom_I_N PF02919.10 EDP44215.1 - 1.1e-80 269.9 0.0 1.1e-80 269.9 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EDP44215.1 - 4.6e-63 212.4 0.1 4.6e-63 212.4 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EDP44215.1 - 2.3e-14 52.8 10.2 1.1e-13 50.6 0.2 3.0 3 0 0 3 3 3 2 C-terminal topoisomerase domain NDUF_B12 PF08122.7 EDP44216.1 - 1.3e-17 63.2 1.3 1.4e-17 63.1 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family PAS PF00989.19 EDP44217.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold Shisa PF13908.1 EDP44217.1 - 2.2 8.4 8.3 4.3 7.4 5.7 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PEPCK_ATP PF01293.15 EDP44218.1 - 2.1e-215 715.6 0.0 2.5e-215 715.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_17 PF13207.1 EDP44218.1 - 0.011 16.5 0.1 1.7 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EDP44218.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EDP44218.1 - 0.26 9.6 0.1 0.38 9.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain Mg_trans_NIPA PF05653.9 EDP44219.1 - 1.8e-90 302.9 23.5 2.4e-90 302.5 16.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EDP44219.1 - 9.3e-06 25.8 4.1 9.3e-06 25.8 2.8 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EDP44219.1 - 1.6e-05 24.9 5.4 1.6e-05 24.9 3.8 3.4 2 1 1 3 3 3 1 EamA-like transporter family DUF3295 PF11702.3 EDP44219.1 - 0.00055 19.0 1.6 0.00084 18.4 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) TFIIA PF03153.8 EDP44219.1 - 0.37 10.6 5.7 0.61 9.9 4.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRPA PF05745.6 EDP44219.1 - 1.1 8.9 9.5 2.6 7.8 1.0 2.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Sigma70_ner PF04546.8 EDP44219.1 - 2 7.9 5.2 3.1 7.3 3.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region LRR_4 PF12799.2 EDP44220.1 - 7.2e-46 153.1 36.1 2.8e-06 26.7 0.2 12.7 6 4 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP44220.1 - 2.4e-43 145.6 44.2 2.1e-08 33.7 0.5 9.4 5 3 3 9 9 9 7 Leucine rich repeat PP2C PF00481.16 EDP44220.1 - 1.9e-38 132.3 0.0 3.2e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 EDP44220.1 - 2.8e-26 91.9 0.0 5.2e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EDP44220.1 - 1e-19 67.5 49.1 0.28 11.3 0.0 19.1 18 3 1 19 19 19 6 Leucine Rich Repeat LRR_7 PF13504.1 EDP44220.1 - 7.3e-09 34.4 52.2 1.1 9.7 0.1 17.2 18 0 0 18 18 18 2 Leucine rich repeat LRR_6 PF13516.1 EDP44220.1 - 9.7e-08 31.3 24.7 2.9 8.2 0.0 12.9 13 1 1 14 14 14 2 Leucine Rich repeat RA PF00788.18 EDP44220.1 - 6.9e-05 23.2 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 EDP44220.1 - 0.00031 20.3 7.6 1 8.9 0.0 4.6 2 1 2 4 4 4 2 Leucine-rich repeat Mito_carr PF00153.22 EDP44221.1 - 1.1e-28 98.6 2.7 3e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein ATP-sulfurylase PF01747.12 EDP44222.1 - 1.1e-78 263.4 0.0 1.6e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EDP44222.1 - 1.2e-55 187.4 0.0 1.9e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EDP44222.1 - 3e-52 176.2 0.0 4.9e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain DUF937 PF06078.6 EDP44222.1 - 0.11 12.7 0.4 0.28 11.3 0.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) CBFD_NFYB_HMF PF00808.18 EDP44223.1 - 4.3e-13 49.1 0.8 4.3e-13 49.1 0.5 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP44223.1 - 0.00054 20.0 0.1 0.0009 19.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.1 EDP44223.1 - 0.067 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component W Ku PF02735.11 EDP44224.1 - 1.7e-27 96.1 0.0 2.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDP44224.1 - 6.3e-09 35.5 0.0 9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain adh_short_C2 PF13561.1 EDP44225.1 - 3.2e-26 92.5 0.0 3.9e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDP44225.1 - 1.5e-20 73.7 0.6 2e-20 73.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP44225.1 - 7.7e-12 45.2 0.2 1.1e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDP44225.1 - 0.05 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EDP44225.1 - 0.056 13.5 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PCP_red PF08369.5 EDP44225.1 - 0.071 12.9 0.2 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Enoyl_reductase PF12241.3 EDP44225.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Nucleocap_ssRNA PF11128.3 EDP44225.1 - 0.087 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Ribosomal_L39 PF00832.15 EDP44226.1 - 1e-20 72.8 10.1 1.2e-20 72.6 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein NUDIX PF00293.23 EDP44227.1 - 1.1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NNMT_PNMT_TEMT PF01234.12 EDP44227.1 - 0.0058 15.6 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family WD40 PF00400.27 EDP44228.1 - 1.6e-42 141.9 10.9 1.9e-07 30.6 0.0 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat Nbas_N PF15492.1 EDP44228.1 - 3.2e-10 39.6 0.3 0.0076 15.3 0.0 3.8 3 1 0 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Lactonase PF10282.4 EDP44228.1 - 0.00014 21.0 1.3 0.0015 17.6 0.2 2.8 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller TFIIIC_delta PF12657.2 EDP44228.1 - 0.00018 21.2 0.2 4.6 6.9 0.1 3.7 2 2 2 4 4 4 1 Transcription factor IIIC subunit delta N-term PQQ_2 PF13360.1 EDP44228.1 - 0.00085 18.8 7.4 0.0048 16.3 0.5 3.5 2 1 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.6 EDP44228.1 - 0.0011 17.8 0.0 1 7.9 0.0 4.1 2 2 3 5 5 5 1 Nup133 N terminal like RAB3GAP2_N PF14655.1 EDP44228.1 - 0.0094 15.0 0.0 0.68 8.8 0.0 3.0 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Apc4_WD40 PF12894.2 EDP44228.1 - 0.011 15.2 0.0 25 4.4 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EDP44228.1 - 0.012 13.8 0.1 0.92 7.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 EDP44228.1 - 0.017 12.9 0.0 1.8 6.2 0.1 2.6 1 1 0 2 2 2 0 IKI3 family A2M_N PF01835.14 EDP44228.1 - 0.052 13.7 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 MG2 domain CPSF_A PF03178.10 EDP44228.1 - 0.073 12.1 0.0 42 3.0 0.0 3.3 3 1 0 3 3 3 0 CPSF A subunit region CNH PF00780.17 EDP44228.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 CNH domain TPR_11 PF13414.1 EDP44229.1 - 7.2e-28 96.0 8.2 8e-10 38.2 0.5 4.0 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EDP44229.1 - 2.8e-23 80.4 3.4 5.4e-06 25.7 0.0 5.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44229.1 - 3.5e-19 67.1 5.6 0.0007 19.3 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44229.1 - 1.1e-14 54.0 12.7 1.2e-06 28.3 0.0 5.2 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44229.1 - 1.2e-14 54.4 3.6 9.5e-06 26.1 1.3 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44229.1 - 2.3e-12 45.7 3.4 0.0087 15.7 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44229.1 - 2e-11 43.4 8.3 0.032 14.8 0.3 6.4 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44229.1 - 1.1e-10 40.8 2.3 0.052 13.7 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44229.1 - 7.7e-10 38.9 11.5 7.6e-06 26.1 2.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44229.1 - 1e-09 37.4 1.3 0.0046 16.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44229.1 - 9.6e-06 25.7 2.8 3.5 8.3 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EDP44229.1 - 3e-05 24.0 16.6 0.018 15.1 1.7 5.3 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44229.1 - 0.00015 21.5 1.4 1.9 8.4 0.0 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDP44229.1 - 0.00016 21.7 3.5 0.16 12.1 0.2 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EDP44229.1 - 0.021 14.7 0.1 3.8 7.4 0.1 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 EDP44229.1 - 0.05 13.1 1.2 0.46 10.0 0.2 2.8 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_10 PF13374.1 EDP44229.1 - 0.081 12.8 0.3 0.081 12.8 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3684 PF12449.3 EDP44230.1 - 0 1195.2 0.0 0 1194.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) CUE PF02845.11 EDP44230.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 CUE domain Diphthamide_syn PF01866.12 EDP44231.1 - 5.8e-61 206.4 0.0 2.6e-34 118.8 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein MRC1 PF09444.5 EDP44232.1 - 1.7e-16 60.8 20.4 1.7e-16 60.8 14.1 3.1 3 0 0 3 3 3 1 MRC1-like domain CALCOCO1 PF07888.6 EDP44233.1 - 0.00034 19.0 4.8 0.00034 19.0 3.4 2.4 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 EDP44233.1 - 0.0047 16.8 2.1 0.0047 16.8 1.4 3.8 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EDP44233.1 - 0.13 12.5 17.2 1.3 9.3 2.7 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 EDP44233.1 - 0.32 10.6 0.1 0.32 10.6 0.1 3.9 3 2 1 4 4 4 0 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 EDP44233.1 - 0.68 9.9 12.4 15 5.6 1.4 3.7 3 0 0 3 3 3 0 bZIP transcription factor DUF4164 PF13747.1 EDP44233.1 - 0.69 10.0 25.1 0.06 13.4 2.4 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.1 EDP44233.1 - 0.7 9.8 23.5 0.24 11.3 2.5 4.2 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 EDP44233.1 - 1.4 9.2 13.7 8.4 6.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF16 PF01519.11 EDP44233.1 - 2.3 8.5 9.5 1.7 8.8 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 Seryl_tRNA_N PF02403.17 EDP44233.1 - 3.1 7.8 17.5 2 8.4 1.3 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.5 EDP44233.1 - 6 6.7 22.3 4 7.3 1.2 3.4 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.1 EDP44233.1 - 6.8 6.0 24.4 1.4 8.3 2.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF2312 PF10073.4 EDP44233.1 - 8 5.9 7.7 8.3 5.8 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) tRNA-synt_1b PF00579.20 EDP44234.1 - 6.3e-62 209.3 0.0 8.3e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EDP44234.1 - 3.1e-06 26.4 0.0 8.2e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain RCC1 PF00415.13 EDP44235.1 - 1.9e-07 31.1 6.6 2.2e-07 30.9 0.0 3.3 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDP44235.1 - 3.4e-07 29.7 9.7 3.3e-06 26.5 0.7 3.5 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Tim17 PF02466.14 EDP44236.1 - 3.2e-30 104.8 3.1 3.9e-30 104.5 2.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APG6 PF04111.7 EDP44237.1 - 8.4e-98 327.2 0.9 9.5e-98 327.1 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 TMCO5 PF14992.1 EDP44237.1 - 0.0013 17.8 9.1 0.0041 16.3 6.0 2.1 1 1 0 1 1 1 1 TMCO5 family CENP-F_leu_zip PF10473.4 EDP44237.1 - 0.0032 17.3 3.7 0.0032 17.3 2.6 2.1 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EDP44237.1 - 0.027 13.4 5.6 0.039 12.8 3.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Transcrip_act PF04949.8 EDP44237.1 - 0.045 13.3 1.6 0.08 12.5 1.1 1.4 1 0 0 1 1 1 0 Transcriptional activator ATP-synt_DE_N PF02823.11 EDP44238.1 - 3.3e-19 68.4 0.1 4.7e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ABC_membrane_2 PF06472.10 EDP44239.1 - 1e-88 297.1 9.2 1.4e-88 296.7 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDP44239.1 - 7.5e-18 65.1 2.3 1.1e-17 64.6 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EDP44239.1 - 0.00095 19.2 0.0 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDP44239.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDP44239.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ODC_AZ PF02100.12 EDP44240.1 - 8.2e-18 63.8 0.0 1.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme SecY PF00344.15 EDP44241.1 - 4.8e-95 318.4 11.8 6.7e-95 317.9 8.2 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDP44241.1 - 2.3e-17 62.1 0.3 6.3e-17 60.7 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 EDP44241.1 - 0.2 11.3 0.0 0.2 11.3 0.0 3.1 4 0 0 4 4 4 0 Tight junction protein, Claudin-like RNA_pol_N PF01194.12 EDP44242.1 - 7.4e-29 99.5 0.7 8.8e-29 99.3 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Transposase_31 PF04754.7 EDP44242.1 - 0.019 14.3 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative transposase, YhgA-like Chordopox_RPO7 PF05864.7 EDP44242.1 - 0.032 14.3 0.2 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) BRE1 PF08647.6 EDP44244.1 - 3.4e-20 71.7 8.7 3.4e-20 71.7 6.0 5.3 6 1 1 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EDP44244.1 - 1.9e-07 30.9 11.1 4.9e-07 29.6 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP44244.1 - 1.9e-06 27.4 11.4 5.2e-06 26.0 7.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP44244.1 - 5.4e-06 25.9 9.1 5.4e-06 25.9 6.3 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44244.1 - 5.7e-06 25.9 10.6 5.7e-06 25.9 7.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EDP44244.1 - 5.2e-05 22.9 3.5 0.00011 21.9 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EDP44244.1 - 0.001 18.8 9.1 0.001 18.8 6.3 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EDP44244.1 - 0.089 12.5 4.7 0.21 11.3 3.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EDP44244.1 - 0.19 11.3 7.9 0.55 9.8 2.2 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EDP44244.1 - 0.31 10.9 10.9 0.11 12.4 4.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING UPF0547 PF10571.4 EDP44244.1 - 0.41 10.3 4.3 0.55 9.9 1.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Bap31 PF05529.7 EDP44244.1 - 3.2 7.1 21.8 0.24 10.8 1.3 4.5 3 2 1 4 4 4 0 B-cell receptor-associated protein 31-like Pyridoxal_deC PF00282.14 EDP44245.1 - 7.1e-10 37.8 0.0 1.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyridoxal_deC PF00282.14 EDP44246.1 - 9.5e-07 27.5 0.0 1.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RFX5_DNA_bdg PF14621.1 EDP44246.1 - 0.041 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain TFIIA PF03153.8 EDP44247.1 - 8.9e-47 160.7 16.4 1.1e-26 94.6 9.2 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 EDP44247.1 - 0.28 10.8 8.3 0.33 10.6 5.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EDP44247.1 - 6.2 4.6 9.7 6.5 4.5 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family PWWP PF00855.12 EDP44248.1 - 9e-17 61.0 0.0 3.3e-16 59.2 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.6 EDP44248.1 - 3.4e-06 26.4 0.0 7.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BSP_II PF05432.6 EDP44248.1 - 0.0033 16.7 29.8 0.0041 16.4 20.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Drc1-Sld2 PF11719.3 EDP44248.1 - 0.03 13.4 26.5 0.047 12.7 18.4 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein MIP-T3 PF10243.4 EDP44248.1 - 0.11 10.9 31.7 0.14 10.6 22.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 EDP44248.1 - 0.29 8.7 14.5 0.35 8.5 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 EDP44248.1 - 0.49 8.6 12.2 0.6 8.3 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pex16 PF08610.5 EDP44248.1 - 0.76 8.7 7.8 0.61 9.0 4.5 1.4 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Hamartin PF04388.7 EDP44249.1 - 3.1e-16 59.2 0.3 3.1e-16 59.2 0.2 3.7 2 1 1 3 3 3 2 Hamartin protein Tropomyosin_1 PF12718.2 EDP44249.1 - 0.031 14.1 25.2 0.21 11.4 2.0 3.2 2 1 0 3 3 3 0 Tropomyosin like DUF1664 PF07889.7 EDP44249.1 - 1.5 8.6 5.8 2.3 8.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EDP44249.1 - 1.5 8.3 16.8 0.15 11.6 1.4 2.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GP41 PF00517.12 EDP44249.1 - 2.6 7.5 8.3 0.56 9.7 1.4 2.5 2 0 0 2 2 2 0 Retroviral envelope protein tRNA-synt_1c PF00749.16 EDP44250.1 - 4e-104 347.6 0.0 8e-104 346.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDP44250.1 - 5.4e-31 107.6 0.0 6.9e-30 103.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EDP44250.1 - 1.1e-29 103.1 1.2 1.5e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EDP44250.1 - 1.2e-10 41.9 1.9 1.2e-10 41.9 1.3 2.0 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PapG_C PF03628.8 EDP44250.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 PapG chaperone-binding domain EMP70 PF02990.11 EDP44251.1 - 5.9e-180 599.1 0.1 5.9e-180 599.1 0.0 1.5 2 0 0 2 2 2 1 Endomembrane protein 70 Sybindin PF04099.7 EDP44252.1 - 4.1e-08 33.0 0.0 8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Sporozoite_P67 PF05642.6 EDP44252.1 - 0.11 10.3 0.3 0.17 9.6 0.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GHMP_kinases_N PF00288.21 EDP44253.1 - 7.1e-07 29.1 3.6 1.6e-06 28.0 2.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Bac_luciferase PF00296.15 EDP44253.1 - 0.0059 15.7 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Ribosomal_L27e PF01777.13 EDP44254.1 - 7.4e-38 128.5 3.3 1e-37 128.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EDP44254.1 - 0.0013 18.3 1.9 0.0023 17.5 1.3 1.4 1 0 0 1 1 1 1 KOW motif DUF3788 PF12663.2 EDP44254.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) DUF1922 PF09082.5 EDP44254.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Ribosom_S12_S23 PF00164.20 EDP44255.1 - 2.5e-37 126.9 0.3 2.9e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 T4_Gp59_C PF08994.5 EDP44255.1 - 0.05 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term CBP4 PF07960.6 EDP44256.1 - 1.4e-10 40.9 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 CBP4 DUF3886 PF13025.1 EDP44256.1 - 0.1 12.5 2.3 0.13 12.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Brix PF04427.13 EDP44257.1 - 9.2e-38 129.8 0.0 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Erg28 PF03694.8 EDP44258.1 - 3.9e-29 100.8 1.0 4.6e-29 100.6 0.7 1.1 1 0 0 1 1 1 1 Erg28 like protein YesK PF14150.1 EDP44258.1 - 0.18 11.9 3.8 0.29 11.2 2.6 1.3 1 0 0 1 1 1 0 YesK-like protein GST_N_2 PF13409.1 EDP44259.1 - 9.6e-16 57.5 0.0 2.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDP44259.1 - 6.9e-13 48.2 0.0 2.2e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDP44259.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDP44259.1 - 0.00036 20.9 0.0 0.00079 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDP44259.1 - 0.0013 18.8 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain RQC PF09382.5 EDP44259.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 RQC domain POT1 PF02765.12 EDP44260.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Myc_N PF01056.13 EDP44261.1 - 0.0027 16.9 1.1 0.0058 15.8 0.8 1.5 1 0 0 1 1 1 1 Myc amino-terminal region WHIM2 PF15613.1 EDP44261.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Myb_Cef PF11831.3 EDP44261.1 - 1.6 7.8 7.3 0.1 11.8 1.3 1.6 2 0 0 2 2 2 0 pre-mRNA splicing factor component Prothymosin PF03247.9 EDP44261.1 - 2.9 8.0 10.7 0.14 12.3 3.0 1.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family Spt5_N PF11942.3 EDP44261.1 - 4.3 8.0 12.7 1.7 9.2 5.2 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EDP44261.1 - 5.8 7.2 8.3 5.5 7.3 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA-synt_2 PF00152.15 EDP44262.1 - 4.6e-88 295.2 0.0 5.5e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDP44262.1 - 5.6e-11 42.1 0.0 1.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDP44262.1 - 1.3e-08 34.3 0.1 6.2e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDP44262.1 - 0.085 12.4 0.0 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) SNase PF00565.12 EDP44263.1 - 4.7e-17 62.2 0.0 1.2e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 Staphylococcal nuclease homologue LRR_4 PF12799.2 EDP44263.1 - 1e-12 47.3 1.7 0.00043 19.8 1.5 4.3 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP44263.1 - 1.2e-11 44.1 14.5 1.9e-08 33.9 2.0 3.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EDP44263.1 - 0.00077 19.1 14.8 1.6 9.0 0.1 6.3 5 2 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 EDP44263.1 - 0.03 14.3 9.5 15 6.0 0.0 5.1 4 1 1 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 EDP44263.1 - 5.1 7.7 13.2 17 6.1 0.1 5.6 5 0 0 5 5 5 0 Leucine rich repeat zf-C3HC4_3 PF13920.1 EDP44264.1 - 5.5e-08 32.3 4.3 7.4e-08 31.9 3.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP44264.1 - 9.3e-08 31.9 9.2 1.3e-07 31.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44264.1 - 4e-06 26.4 7.8 5.7e-06 25.9 5.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDP44264.1 - 2.2e-05 24.1 7.1 3.1e-05 23.6 4.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDP44264.1 - 0.00027 20.7 7.4 0.00049 19.9 5.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDP44264.1 - 0.00037 20.1 4.5 0.00094 18.8 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EDP44264.1 - 0.00041 19.9 8.7 0.00064 19.3 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDP44264.1 - 0.016 14.6 2.6 0.027 13.9 1.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L34e PF01199.13 EDP44264.1 - 0.084 13.1 0.3 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L34e zf-RanBP PF00641.13 EDP44264.1 - 0.27 10.3 3.5 1.2 8.3 2.6 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FYVE PF01363.16 EDP44264.1 - 0.44 10.4 6.0 1.3 9.0 4.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-3CxxC PF13695.1 EDP44264.1 - 1.6 9.0 4.7 4.1 7.6 3.3 1.7 1 1 0 1 1 1 0 Zinc-binding domain GATase_5 PF13507.1 EDP44265.1 - 5.7e-95 317.1 0.0 9.3e-95 316.4 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EDP44265.1 - 8e-43 146.0 0.1 2.2e-24 86.2 0.0 2.6 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EDP44265.1 - 5.2e-22 77.8 0.0 2e-21 76.0 0.0 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain SWIRM PF04433.12 EDP44266.1 - 1.8e-07 31.1 0.1 4.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain zf-CCCH PF00642.19 EDP44267.1 - 1.6e-12 46.8 13.9 1.8e-06 27.4 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EDP44267.1 - 0.00089 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP44267.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EDP44268.1 - 1e-10 41.2 0.1 1.4e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Ras family DUF3510 PF12022.3 EDP44268.1 - 0.11 12.5 0.1 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) zf-DHHC PF01529.15 EDP44269.1 - 2.8e-35 121.2 0.4 4.8e-35 120.5 0.0 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.16 EDP44269.1 - 0.031 14.1 3.7 0.19 11.6 1.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger zf-SNAP50_C PF12251.3 EDP44270.1 - 6.1e-11 42.0 0.4 1.6e-10 40.6 0.0 2.0 1 1 1 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal PI3_PI4_kinase PF00454.22 EDP44271.1 - 5.2e-20 71.9 0.0 8.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RNA_pol_I_TF PF04090.7 EDP44272.1 - 1.6e-11 43.8 3.1 1.2e-09 37.7 0.1 3.0 1 1 2 3 3 3 2 RNA polymerase I specific initiation factor TPR_11 PF13414.1 EDP44272.1 - 0.024 14.2 1.1 0.25 11.0 0.0 2.7 3 0 0 3 3 3 0 TPR repeat PP2C PF00481.16 EDP44273.1 - 1.3e-69 234.4 0.4 1.6e-69 234.1 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C UCR_Fe-S_N PF10399.4 EDP44273.1 - 0.14 11.3 0.1 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ATP11 PF06644.6 EDP44274.1 - 5.3e-72 242.5 1.2 6.3e-72 242.2 0.8 1.0 1 0 0 1 1 1 1 ATP11 protein DUF3280 PF11684.3 EDP44274.1 - 0.01 16.0 1.0 0.019 15.1 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2380) GWT1 PF06423.7 EDP44275.1 - 4.5e-30 104.5 0.5 2.1e-29 102.3 0.0 2.4 3 0 0 3 3 3 1 GWT1 OSCP PF00213.13 EDP44276.1 - 1.7e-34 119.1 0.6 2e-34 118.9 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit eIF-3c_N PF05470.7 EDP44277.1 - 3.6e-173 576.8 12.3 3.6e-173 576.8 8.5 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EDP44277.1 - 2.6e-15 56.5 0.1 1.9e-14 53.8 0.0 2.7 2 0 0 2 2 2 1 PCI domain Daxx PF03344.10 EDP44277.1 - 0.5 8.7 26.0 0.78 8.1 18.0 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EDP44277.1 - 1.2 7.1 17.3 2.8 5.8 12.0 1.7 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EDP44277.1 - 2.8 7.1 13.8 4.9 6.3 9.6 1.4 1 0 0 1 1 1 0 NOA36 protein Dfp1_Him1_M PF08630.5 EDP44278.1 - 1.1e-26 93.0 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EDP44278.1 - 8.8e-18 63.7 3.0 1.7e-17 62.7 2.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EDP44278.1 - 2e-05 24.3 0.0 5.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDP44278.1 - 3.9e-05 23.7 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PPDK_N PF01326.14 EDP44278.1 - 0.041 12.9 0.0 0.086 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RNase_H PF00075.19 EDP44279.1 - 6.1e-31 107.4 0.0 9.4e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EDP44279.1 - 1.5e-16 60.1 0.1 2.7e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Piwi PF02171.12 EDP44279.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Piwi domain RVT_3 PF13456.1 EDP44279.1 - 0.13 12.0 0.0 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like DUF1323 PF07037.6 EDP44279.1 - 0.65 10.1 2.7 1.8 8.7 1.9 1.8 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) FAD_binding_1 PF00667.15 EDP44280.1 - 1.5e-51 174.9 0.0 4.1e-51 173.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EDP44280.1 - 2.3e-29 102.2 0.0 4.4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDP44280.1 - 6.2e-19 68.5 0.0 1.5e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Rad10 PF03834.9 EDP44281.1 - 2.1e-31 107.4 0.2 4.8e-30 103.0 0.1 2.2 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EDP44281.1 - 4.6e-05 23.5 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.15 EDP44281.1 - 0.017 14.6 3.9 0.038 13.5 2.7 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif HHH_2 PF12826.2 EDP44281.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ribosomal_S8e PF01201.17 EDP44282.1 - 1.3e-36 125.6 10.3 5.8e-36 123.5 7.1 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EDP44282.1 - 0.036 13.9 0.8 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Mer2 Macoilin PF09726.4 EDP44282.1 - 0.22 9.7 9.4 0.3 9.3 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Yip1 PF04893.12 EDP44283.1 - 6.4e-12 45.3 8.8 8.9e-12 44.8 6.1 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 EDP44283.1 - 0.27 11.1 1.5 0.62 10.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) DNA_mis_repair PF01119.14 EDP44284.1 - 1.2e-31 108.6 0.0 2.9e-31 107.4 0.0 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Lipoprotein_15 PF03640.10 EDP44285.1 - 1.9e-05 23.9 5.1 17 4.9 0.0 5.2 5 0 0 5 5 5 2 Secreted repeat of unknown function Enamelin PF15362.1 EDP44285.1 - 0.006 14.7 1.1 0.74 7.8 0.1 2.0 1 1 1 2 2 2 2 Enamelin Phage_fiber_C PF06820.7 EDP44285.1 - 0.0086 16.1 3.2 62 3.8 0.0 4.7 1 1 4 5 5 5 0 Putative prophage tail fibre C-terminus OxoDH_E1alpha_N PF12573.3 EDP44285.1 - 0.11 12.0 3.7 49 3.5 0.0 3.7 4 0 0 4 4 4 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal MSA-2c PF12238.3 EDP44285.1 - 9.5 5.8 8.4 41 3.7 0.0 3.2 1 1 1 2 2 2 0 Merozoite surface antigen 2c RNase_PH PF01138.16 EDP44286.1 - 1.4e-11 44.8 0.0 2.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDP44286.1 - 3.4e-06 26.8 0.0 2.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 PTPA PF03095.10 EDP44288.1 - 1.5e-109 365.8 0.0 1.8e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.27 EDP44289.1 - 1.4e-16 59.6 0.5 0.00017 21.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Abhydrolase_4 PF08386.5 EDP44289.1 - 0.09 12.6 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein RabGAP-TBC PF00566.13 EDP44290.1 - 1.3e-38 132.6 0.0 1.9e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_9 PF14604.1 EDP44290.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.12 EDP44290.1 - 0.023 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Thymidylate_kin PF02223.12 EDP44290.1 - 0.27 10.5 0.0 8.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase Pkinase PF00069.20 EDP44291.1 - 8.8e-56 188.9 0.0 1.3e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44291.1 - 3.6e-33 114.7 0.0 1.4e-32 112.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44291.1 - 4.9e-05 22.4 0.0 0.00014 20.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EDP44291.1 - 0.094 12.4 0.1 0.094 12.4 0.1 3.8 3 2 1 4 4 4 0 Phosphotransferase enzyme family DnaG_DnaB_bind PF08278.6 EDP44292.1 - 0.019 15.2 0.7 0.035 14.3 0.5 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PB1 PF00564.19 EDP44292.1 - 0.039 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 PB1 domain SPC22 PF04573.7 EDP44294.1 - 1.4e-28 99.3 0.1 1.6e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit CI-B14_5a PF07347.7 EDP44295.1 - 0.0094 15.6 0.3 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Oxysterol_BP PF01237.13 EDP44296.1 - 9e-124 412.5 0.0 1.6e-123 411.7 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EDP44296.1 - 4.7e-14 52.0 0.3 4.8e-05 23.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EDP44296.1 - 4.3e-12 45.1 0.6 0.00016 21.3 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EDP44296.1 - 2e-10 39.8 0.1 0.018 15.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 EDP44296.1 - 1.2e-09 38.3 0.1 4.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 EDP44296.1 - 1.5e-08 34.8 0.4 0.00014 22.1 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDP44296.1 - 4.2e-08 33.4 0.0 0.0017 18.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.1 EDP44296.1 - 1.2e-06 28.5 0.1 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDP44296.1 - 3.7e-06 27.1 0.3 2.3e-05 24.6 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain DASH_Duo1 PF08651.5 EDP44297.1 - 4.4e-14 51.8 1.5 8.5e-14 50.8 1.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 Retrotrans_gag PF03732.12 EDP44297.1 - 0.2 11.7 1.6 0.38 10.8 1.1 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein Tom37_C PF11801.3 EDP44297.1 - 0.71 9.7 3.9 0.45 10.3 0.9 1.9 1 1 1 2 2 2 0 Tom37 C-terminal domain Adeno_PIX PF03955.9 EDP44297.1 - 8.1 7.0 6.9 2.3 8.7 0.1 2.6 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) ABA_GPCR PF12430.3 EDP44298.1 - 5.2e-41 139.9 7.4 7.5e-41 139.4 5.2 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EDP44298.1 - 5.7e-15 55.1 0.4 5.7e-15 55.1 0.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) Adaptin_N PF01602.15 EDP44299.1 - 0.19 10.0 2.2 0.13 10.5 0.4 1.5 2 0 0 2 2 2 0 Adaptin N terminal region FSH1 PF03959.8 EDP44300.1 - 3e-57 193.4 0.0 3.8e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDP44300.1 - 1e-10 41.8 0.0 4.3e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP44300.1 - 7.4e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDP44300.1 - 2.5e-06 27.0 0.1 0.00014 21.3 0.1 2.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 EDP44300.1 - 1.5e-05 24.4 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 EDP44300.1 - 3.8e-05 23.5 0.0 0.17 11.5 0.0 2.4 2 1 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EDP44300.1 - 0.006 16.1 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold ubiquitin PF00240.18 EDP44301.1 - 7.4e-21 73.3 0.1 1.2e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EDP44301.1 - 7.9e-20 70.0 0.3 1.3e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 EDP44301.1 - 8.8e-15 53.9 3.3 1.9e-14 52.8 2.3 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EDP44301.1 - 1.3e-09 37.5 0.1 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EDP44301.1 - 0.0024 17.7 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDP44301.1 - 0.0098 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EDP44301.1 - 0.025 14.8 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_4 PF14555.1 EDP44301.1 - 0.11 12.0 0.0 0.95 9.0 0.0 2.6 3 0 0 3 3 3 0 UBA-like domain CASP_C PF08172.7 EDP44302.1 - 3.3e-31 108.2 13.3 3.3e-31 108.2 9.2 4.8 1 1 3 4 4 4 1 CASP C terminal ALIX_LYPXL_bnd PF13949.1 EDP44302.1 - 0.0072 15.3 46.2 0.0089 15.0 7.0 3.5 1 1 1 3 3 3 2 ALIX V-shaped domain binding to HIV WD40_alt PF14077.1 EDP44302.1 - 0.11 12.1 4.3 15 5.3 0.1 4.3 4 1 1 5 5 5 0 Alternative WD40 repeat motif PspA_IM30 PF04012.7 EDP44302.1 - 0.47 9.7 75.3 0.083 12.2 32.4 4.3 1 1 4 5 5 5 0 PspA/IM30 family DUF869 PF05911.6 EDP44302.1 - 2.1 6.4 45.5 0.8 7.8 6.1 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EDP44302.1 - 5.6 6.5 66.6 1.1 8.8 4.6 3.9 1 1 2 4 4 4 0 IncA protein DUF1664 PF07889.7 EDP44302.1 - 6.4 6.5 28.7 0.54 10.0 0.1 5.4 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) CPSase_sm_chain PF00988.17 EDP44303.1 - 5.8e-45 151.9 0.0 8.5e-45 151.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EDP44303.1 - 2.4e-35 121.7 0.0 3.4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDP44303.1 - 1.4e-05 24.6 0.1 0.00013 21.4 0.2 2.3 2 1 0 2 2 2 1 Peptidase C26 zf-met PF12874.2 EDP44304.1 - 1.4e-06 28.2 0.7 3.1e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDP44304.1 - 3.6e-05 23.7 0.3 6.6e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 EDP44304.1 - 0.003 17.3 7.8 0.003 17.3 5.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-U1 PF06220.7 EDP44304.1 - 0.11 12.0 0.6 0.29 10.7 0.4 1.7 1 0 0 1 1 1 0 U1 zinc finger SusD PF07980.6 EDP44304.1 - 4.4 6.7 7.3 7.3 6.0 5.1 1.3 1 0 0 1 1 1 0 SusD family tRNA-synt_1 PF00133.17 EDP44305.1 - 6.3e-224 744.4 0.0 8e-224 744.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDP44305.1 - 9.1e-25 87.1 0.0 2.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDP44305.1 - 2e-18 66.2 0.3 1.3e-06 27.3 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EDP44305.1 - 6.8e-05 22.1 0.0 0.0069 15.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ATP-synt PF00231.14 EDP44306.1 - 9.1e-72 241.8 1.0 1.1e-71 241.6 0.7 1.0 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.12 EDP44307.1 - 7.1e-46 154.9 0.6 1.1e-45 154.2 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EDP44307.1 - 0.0089 15.3 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Arc_trans_TRASH PF08394.5 EDP44307.1 - 0.99 9.6 5.9 1.2 9.3 0.1 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain SAP PF02037.22 EDP44309.1 - 1.3e-11 43.7 0.3 5.2e-11 41.7 0.2 2.1 1 0 0 1 1 1 1 SAP domain Tmemb_cc2 PF10267.4 EDP44309.1 - 0.0011 17.5 3.0 0.0014 17.3 2.1 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CCT_2 PF09425.5 EDP44309.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Divergent CCT motif vMSA PF00695.14 EDP44309.1 - 0.29 10.2 2.7 0.36 9.9 1.9 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Adaptin_binding PF10199.4 EDP44309.1 - 1.9 8.7 8.2 3.8 7.7 5.7 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ArfGap PF01412.13 EDP44311.1 - 1.7e-41 140.6 2.4 2.1e-41 140.3 1.0 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf SNF2_N PF00176.18 EDP44312.1 - 5.4e-70 235.5 0.1 8.2e-70 234.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP44312.1 - 1.7e-12 46.9 0.0 1.7e-11 43.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP44312.1 - 6.5e-10 38.7 0.1 3.5e-09 36.3 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EDP44312.1 - 8e-06 25.7 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PPTA PF01239.17 EDP44313.1 - 2.5e-12 45.5 1.1 5.1e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat Mitofilin PF09731.4 EDP44313.1 - 0.063 11.9 0.0 0.069 11.7 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Yae1_N PF09811.4 EDP44314.1 - 3.2e-10 39.3 1.5 4.4e-10 38.9 1.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal EBP PF05241.7 EDP44315.1 - 8.5e-53 178.2 7.2 9.7e-53 178.0 5.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Bromodomain PF00439.20 EDP44317.1 - 5.2e-25 87.1 0.1 1.2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EDP44317.1 - 1.7e-10 40.9 0.1 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDP44317.1 - 3.9e-09 36.4 0.0 8.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ANTH PF07651.11 EDP44318.1 - 6.6e-33 113.6 3.6 1.1e-32 112.9 2.5 1.3 1 0 0 1 1 1 1 ANTH domain PTR2 PF00854.16 EDP44319.1 - 5.7 5.6 9.9 9.9 4.8 2.6 2.2 2 0 0 2 2 2 0 POT family DUF2431 PF10354.4 EDP44320.1 - 4.3e-26 91.8 0.0 6.2e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.1 EDP44320.1 - 0.052 13.8 1.5 0.052 13.8 1.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_11 PF13414.1 EDP44321.1 - 6.1e-22 77.0 11.1 8.7e-12 44.5 0.4 5.4 2 1 4 6 6 6 5 TPR repeat DnaJ PF00226.26 EDP44321.1 - 1.1e-21 76.2 1.3 2.5e-21 75.1 0.1 2.3 2 0 0 2 2 1 1 DnaJ domain TPR_1 PF00515.23 EDP44321.1 - 3.1e-15 55.0 0.5 0.034 13.7 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44321.1 - 3.3e-15 54.7 5.9 0.0015 18.2 0.2 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44321.1 - 4e-15 55.9 21.0 0.0051 17.1 0.0 6.9 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44321.1 - 2.4e-13 50.3 11.7 5.4e-05 23.7 1.8 5.5 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44321.1 - 6.1e-12 45.2 4.5 1.6e-06 27.8 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44321.1 - 5.2e-10 39.0 13.5 0.15 12.8 0.5 8.5 3 3 6 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44321.1 - 1.2e-09 37.5 0.5 0.0056 16.7 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EDP44321.1 - 1.9e-08 34.2 3.5 0.00084 19.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EDP44321.1 - 2.4e-07 30.0 0.7 0.86 9.5 0.1 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44321.1 - 2.5e-05 24.4 19.3 4.1 8.0 0.1 8.3 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDP44321.1 - 0.00081 19.4 2.1 0.17 12.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EDP44321.1 - 0.0012 19.1 6.5 1.5 9.1 0.1 3.8 2 1 2 4 4 4 2 Bacterial transcriptional activator domain PPR PF01535.15 EDP44321.1 - 0.011 15.6 1.0 13 5.9 0.0 4.4 4 0 0 4 4 4 0 PPR repeat TPR_7 PF13176.1 EDP44321.1 - 0.012 15.4 9.9 1 9.3 0.0 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44321.1 - 0.025 14.5 17.4 0.55 10.2 0.0 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EDP44321.1 - 0.039 13.7 0.2 1.6 8.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDP44321.1 - 0.043 13.7 1.5 3.4 7.7 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR_2 PF13041.1 EDP44321.1 - 0.19 11.7 0.4 28 4.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family DUF3856 PF12968.2 EDP44321.1 - 0.2 11.5 3.6 5.2 6.8 0.0 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Lumazine_bd PF12870.2 EDP44321.1 - 2 8.4 4.6 1.1 9.2 0.3 2.2 2 0 0 2 2 2 0 Lumazine-binding domain Bax1-I PF01027.15 EDP44322.1 - 4e-42 144.1 25.3 4.6e-42 143.9 17.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EDP44322.1 - 1.8 7.9 14.0 2.8 7.3 0.5 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Fe-S_biosyn PF01521.15 EDP44323.1 - 2.8e-18 65.8 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MMR_HSR1 PF01926.18 EDP44324.1 - 1.4e-18 66.9 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP44324.1 - 1.9e-07 30.4 0.0 1.7e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDP44324.1 - 0.00014 21.4 0.0 0.2 11.0 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDP44324.1 - 0.00019 21.3 0.0 0.12 12.2 0.0 2.2 1 1 1 2 2 2 2 Dynamin family Arf PF00025.16 EDP44324.1 - 0.0012 18.0 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.22 EDP44324.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 EDP44324.1 - 0.0046 16.2 0.0 0.043 13.0 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EDP44324.1 - 0.024 13.4 0.0 0.28 9.9 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EDP44324.1 - 0.03 14.6 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EDP44324.1 - 0.051 14.0 0.0 0.18 12.2 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Serinc PF03348.10 EDP44325.1 - 1.8e-134 448.7 11.0 2.1e-134 448.4 7.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2231 PF09990.4 EDP44325.1 - 0.037 14.3 0.1 0.037 14.3 0.0 3.9 3 1 2 5 5 5 0 Predicted membrane protein (DUF2231) TRP PF06011.7 EDP44325.1 - 0.16 10.4 13.5 2.1 6.7 9.4 2.5 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Pterin_bind PF00809.17 EDP44326.1 - 1.6e-63 213.8 0.0 2.6e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EDP44326.1 - 9.3e-41 138.5 0.0 1.4e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EDP44327.1 - 3.3e-17 62.6 0.0 2e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase DUF2284 PF10050.4 EDP44327.1 - 0.059 12.9 0.1 0.07 12.7 0.1 1.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) EST1_DNA_bind PF10373.4 EDP44328.1 - 0.00048 19.4 0.0 0.00091 18.5 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DNA_pol_E_B PF04042.11 EDP44329.1 - 9.2e-41 139.3 0.0 1.5e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 EDP44329.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal DUF2428 PF10350.4 EDP44330.1 - 8.1e-38 129.9 1.5 8.1e-38 129.9 1.1 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EDP44330.1 - 0.00013 21.7 7.1 0.013 15.4 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.1 EDP44330.1 - 0.0044 17.2 9.0 0.061 13.6 0.1 4.4 2 2 1 4 4 4 1 HEAT repeats Adaptin_N PF01602.15 EDP44330.1 - 0.24 9.6 4.4 0.092 11.0 0.1 2.3 3 0 0 3 3 3 0 Adaptin N terminal region HEAT_EZ PF13513.1 EDP44330.1 - 2.1 8.9 9.4 0.66 10.5 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat PIGA PF08288.7 EDP44331.1 - 2.2e-41 140.0 0.2 5e-41 138.9 0.1 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EDP44331.1 - 7.3e-25 87.3 0.0 1.1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDP44331.1 - 1.3e-17 64.0 0.3 2.5e-17 63.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDP44331.1 - 2.8e-12 47.0 0.6 6.6e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EDP44331.1 - 6.2e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EDP44331.1 - 0.00092 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like tRNA-synt_2c PF01411.14 EDP44332.1 - 1.8e-216 719.7 0.0 2.2e-216 719.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDP44332.1 - 2.1e-15 56.3 0.2 5.4e-15 54.9 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EDP44332.1 - 5.4e-05 22.8 0.5 0.00016 21.2 0.4 1.8 1 0 0 1 1 1 1 DHHA1 domain zf-C2H2 PF00096.21 EDP44333.1 - 6.8e-13 48.1 20.0 7.5e-06 25.9 0.7 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDP44333.1 - 2e-09 37.2 16.5 0.0005 20.2 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDP44333.1 - 2.4e-07 30.6 22.7 0.00067 19.8 0.3 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDP44333.1 - 3.3e-07 29.9 2.1 0.0045 16.8 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDP44333.1 - 0.0075 16.3 0.7 4.6 7.5 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EDP44333.1 - 0.01 15.5 6.9 0.15 11.7 0.2 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.2 EDP44333.1 - 0.15 12.3 3.5 14 6.0 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EDP44333.1 - 3.1 7.8 10.6 0.21 11.5 0.3 3.3 3 1 1 4 4 4 0 Zinc ribbon domain Aldedh PF00171.17 EDP44336.1 - 2.7e-186 619.4 0.1 3e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDP44336.1 - 0.0014 17.9 0.0 0.0068 15.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) BMC PF00936.14 EDP44336.1 - 0.0033 17.0 0.3 0.0093 15.6 0.0 1.8 2 0 0 2 2 2 1 BMC domain PT-VENN PF04829.8 EDP44336.1 - 0.074 12.6 6.4 0.029 13.9 2.2 2.0 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Sugar_tr PF00083.19 EDP44337.1 - 6.9e-50 169.9 14.7 8.1e-50 169.6 10.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDP44337.1 - 4.2e-11 42.1 10.6 5.1e-11 41.8 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDP44337.1 - 0.0002 19.9 10.0 0.0002 19.9 7.0 1.8 1 1 0 2 2 2 1 MFS/sugar transport protein TB2_DP1_HVA22 PF03134.14 EDP44337.1 - 0.051 13.3 1.3 0.13 12.0 0.9 1.7 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Bax1-I PF01027.15 EDP44337.1 - 1.1 8.8 15.8 0.13 11.8 6.3 2.2 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 HLH PF00010.21 EDP44338.1 - 0.00011 21.7 3.7 0.00054 19.6 2.6 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain GST_C_2 PF13410.1 EDP44338.1 - 0.091 12.6 1.2 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1509 PF07420.6 EDP44338.1 - 0.16 11.1 1.7 0.22 10.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF3635 PF12330.3 EDP44339.1 - 3.6e-15 55.8 0.8 1e-14 54.4 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3635) APH PF01636.18 EDP44339.1 - 0.026 14.2 0.1 0.026 14.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L1 PF00687.16 EDP44340.1 - 1.2e-22 80.3 0.0 7.1e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family CGI-121 PF08617.5 EDP44343.1 - 1.4e-30 106.0 0.0 1.8e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pribosyltran PF00156.22 EDP44344.1 - 1.3e-17 63.7 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDP44344.1 - 2.7e-05 23.4 0.0 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HpcH_HpaI PF03328.9 EDP44346.1 - 3e-18 65.5 0.2 3.4e-18 65.3 0.1 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EDP44346.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold ABC_tran PF00005.22 EDP44347.1 - 4.6e-37 127.3 0.0 1.2e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDP44347.1 - 5e-27 95.0 10.5 8.7e-27 94.2 7.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDP44347.1 - 3.1e-07 30.6 0.1 0.00028 20.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EDP44347.1 - 9.5e-06 24.9 0.0 0.001 18.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDP44347.1 - 0.00027 20.9 0.2 0.00066 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EDP44347.1 - 0.00045 19.6 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDP44347.1 - 0.0038 16.4 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDP44347.1 - 0.0057 17.4 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDP44347.1 - 0.0075 16.4 0.2 0.051 13.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP44347.1 - 0.038 13.7 0.0 0.26 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDP44347.1 - 0.05 13.9 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDP44347.1 - 0.06 12.7 0.2 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EDP44347.1 - 0.07 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 EDP44347.1 - 0.098 11.3 0.0 0.098 11.3 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.1 EDP44347.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain dUTPase PF00692.14 EDP44348.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 dUTPase HCMVantigenic_N PF12154.3 EDP44348.1 - 4.9 7.1 7.9 0.97 9.3 1.1 2.4 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV BCDHK_Adom3 PF10436.4 EDP44349.1 - 3.5e-45 153.4 0.0 4.7e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDP44349.1 - 5.5e-13 48.6 0.0 2.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDP44349.1 - 6.1e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EDP44349.1 - 0.084 12.6 0.1 0.72 9.6 0.0 2.3 2 1 1 3 3 3 0 Histidine kinase-like ATPase domain V-SNARE PF05008.10 EDP44350.1 - 2.4e-17 62.8 0.8 2.4e-17 62.8 0.6 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EDP44350.1 - 8e-11 41.8 0.8 8e-11 41.8 0.6 2.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus UTRA PF07702.8 EDP44350.1 - 0.012 15.2 0.1 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 UTRA domain Tup_N PF08581.5 EDP44350.1 - 0.12 12.5 2.1 3.3 7.9 0.3 3.1 2 1 1 3 3 3 0 Tup N-terminal Gluconate_2-dh3 PF13618.1 EDP44350.1 - 3.9 7.6 7.5 2 8.5 0.4 2.2 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 WD40 PF00400.27 EDP44351.1 - 1.4e-20 72.3 8.7 0.00013 21.7 0.6 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat IGR PF09597.5 EDP44352.1 - 4.9e-13 48.7 0.0 7.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif PAF-AH_p_II PF03403.8 EDP44353.1 - 3.7e-43 147.2 0.9 4.5e-22 77.8 0.0 4.1 2 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EDP44353.1 - 7.8e-11 41.9 0.0 7.1e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP44353.1 - 1.4e-06 28.4 0.6 2.2e-05 24.4 0.4 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EDP44353.1 - 2.5e-06 26.5 0.0 2.9e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDP44353.1 - 3.7e-05 22.6 0.0 0.00034 19.5 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EDP44353.1 - 7.1e-05 22.5 0.3 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 Putative lysophospholipase UQ_con PF00179.21 EDP44354.1 - 3.4e-37 127.0 0.0 4.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EDP44354.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain AMP-binding PF00501.23 EDP44355.1 - 4.5e-82 275.6 0.0 5.6e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDP44355.1 - 3.1e-10 40.8 0.0 7.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EDP44355.1 - 0.0013 17.3 0.0 0.04 12.4 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Carb_kinase PF01256.12 EDP44356.1 - 2.6e-34 118.5 0.0 3.2e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase MNNL PF07657.8 EDP44356.1 - 0.083 12.8 0.6 9.5 6.2 0.0 2.2 2 0 0 2 2 2 0 N terminus of Notch ligand dCMP_cyt_deam_2 PF08211.6 EDP44358.1 - 1.3e-08 34.8 0.1 1.4e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.17 EDP44358.1 - 1e-05 25.0 0.0 1.2e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Hydantoinase_A PF01968.13 EDP44359.1 - 4.5e-90 301.6 1.2 7.6e-90 300.9 0.8 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDP44359.1 - 2.7e-59 199.6 0.3 3.3e-57 192.8 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region WD40 PF00400.27 EDP44360.1 - 0.0001 22.0 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat GST_C_3 PF14497.1 EDP44361.1 - 0.00064 20.1 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 EDP44362.1 - 2.7e-43 145.5 3.1 7.4e-15 54.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1639 PF07797.9 EDP44362.1 - 0.096 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Coatomer_E PF04733.9 EDP44363.1 - 1.2e-31 110.0 1.6 1.3e-31 109.8 1.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.1 EDP44363.1 - 1e-05 25.7 10.1 0.067 13.8 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44363.1 - 2.5e-05 24.8 7.7 0.33 11.7 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44363.1 - 0.00025 20.7 2.8 0.64 10.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDP44363.1 - 0.00071 19.1 0.3 0.073 12.7 0.0 3.3 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 EDP44363.1 - 0.0013 19.0 5.7 1.3 9.3 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDP44363.1 - 0.0017 18.6 4.8 0.67 10.5 1.7 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EDP44363.1 - 0.0035 16.1 0.1 0.4 9.3 0.0 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EDP44363.1 - 0.0036 17.4 0.2 0.24 11.5 0.0 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDP44363.1 - 0.0056 17.0 2.9 3.7 8.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDP44363.1 - 0.012 15.1 0.0 2.1 8.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44363.1 - 0.022 14.9 0.4 9 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat peroxidase PF00141.18 EDP44364.1 - 7.1e-50 169.6 0.0 1.2e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase IN_DBD_C PF00552.16 EDP44364.1 - 0.11 11.9 0.1 10 5.6 0.0 2.5 2 0 0 2 2 2 0 Integrase DNA binding domain HemX PF04375.9 EDP44364.1 - 0.12 10.9 0.1 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 HemX GDI PF00996.13 EDP44366.1 - 7.1e-162 538.6 0.0 8.2e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Colicin_Pyocin PF01320.13 EDP44367.1 - 0.056 13.3 1.1 0.34 10.8 0.2 2.0 1 1 1 2 2 2 0 Colicin immunity protein / pyocin immunity protein Ribosomal_L22 PF00237.14 EDP44368.1 - 9.4e-22 76.9 0.1 1.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Aldedh PF00171.17 EDP44369.1 - 5.9e-160 532.5 0.0 6.7e-160 532.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDP44369.1 - 0.0072 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EDP44369.1 - 0.075 12.2 0.1 0.15 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pro_isomerase PF00160.16 EDP44370.1 - 2.1e-44 151.4 0.1 2.4e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RhoGAP PF00620.22 EDP44371.1 - 9.6e-37 125.9 0.3 2.2e-36 124.7 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain Pro_isomerase PF00160.16 EDP44372.1 - 4.1e-45 153.7 0.1 6.4e-45 153.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EDP44372.1 - 8.3e-09 34.9 6.9 0.00026 20.5 0.4 2.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EDP44372.1 - 6.7e-07 28.7 6.7 6.9e-05 22.4 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP44372.1 - 5e-06 25.8 3.8 5.6e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44372.1 - 0.00078 19.3 1.7 0.11 12.4 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44372.1 - 0.0092 15.6 1.3 0.067 12.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44372.1 - 0.043 14.2 2.2 1.3 9.6 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44372.1 - 0.21 11.4 4.6 3.3 7.6 2.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44372.1 - 2 9.2 8.4 2.9 8.7 2.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 EDP44372.1 - 3.2 7.8 16.8 2.5 8.2 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Aminotran_5 PF00266.14 EDP44373.1 - 2.7e-29 102.0 0.0 4.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Methyltransf_16 PF10294.4 EDP44374.1 - 3.9e-10 39.4 0.0 2.6e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EDP44374.1 - 1.2 9.1 4.1 0.7 9.9 0.5 2.4 2 2 0 2 2 2 0 Methyltransferase domain P34-Arc PF04045.9 EDP44375.1 - 1.2e-80 270.3 0.0 1.7e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PGP_phosphatase PF09419.5 EDP44376.1 - 4.1e-38 130.3 0.0 8e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase CDC27 PF09507.5 EDP44377.1 - 0.00059 19.1 11.0 0.00069 18.9 7.6 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1764 PF08576.5 EDP44377.1 - 0.00092 19.9 18.1 2.4 9.0 12.6 3.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) KIAA1328 PF15369.1 EDP44377.1 - 0.95 9.2 5.4 1.1 8.9 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 HGTP_anticodon2 PF12745.2 EDP44377.1 - 6 5.9 7.4 7.6 5.5 5.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4551 PF15087.1 EDP44377.1 - 6 5.0 6.4 6.7 4.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DSHCT PF08148.7 EDP44378.1 - 1.3e-52 177.7 0.0 2.8e-52 176.5 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDP44378.1 - 2.9e-21 75.7 0.0 5.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EDP44378.1 - 6.8e-06 25.4 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EDP44378.1 - 2.9e-05 23.8 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDP44378.1 - 0.00076 19.3 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EDP44378.1 - 0.095 11.9 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Arrestin_N PF00339.24 EDP44379.1 - 8.5e-05 22.4 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain MtrE PF04206.7 EDP44379.1 - 0.11 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E PC-Esterase PF13839.1 EDP44380.1 - 4.8e-10 39.6 0.1 1e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p I_LWEQ PF01608.12 EDP44381.1 - 4e-61 205.4 7.1 4e-61 205.4 4.9 4.5 4 1 2 7 7 7 1 I/LWEQ domain ANTH PF07651.11 EDP44381.1 - 4.1e-40 137.2 0.2 4.1e-40 137.2 0.1 2.5 2 0 0 2 2 2 1 ANTH domain ATP-synt_ab PF00006.20 EDP44381.1 - 1.8 8.0 6.0 0.58 9.6 1.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_16 PF13432.1 EDP44382.1 - 3.5e-11 43.4 6.8 8.4e-05 23.1 0.0 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44382.1 - 5.4e-10 39.0 6.4 0.0019 18.6 0.0 5.7 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44382.1 - 2.3e-08 34.2 0.0 0.047 14.0 0.0 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat Suf PF05843.9 EDP44382.1 - 2.1e-07 30.9 0.0 1.7e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EDP44382.1 - 3.2e-06 26.6 3.3 0.14 12.1 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44382.1 - 3.2e-06 27.2 2.1 0.0041 17.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44382.1 - 4e-06 26.6 6.3 0.028 14.3 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDP44382.1 - 0.0024 18.1 3.3 3.4 8.3 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44382.1 - 0.0061 16.2 0.0 2.9 7.9 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 EDP44382.1 - 0.043 13.2 0.4 0.12 11.7 0.1 2.0 1 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 EDP44382.1 - 0.048 13.2 0.0 4.9 6.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Herpes_UL14 PF03580.9 EDP44382.1 - 0.19 11.5 5.0 0.12 12.1 1.5 2.1 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Fis1_TPR_C PF14853.1 EDP44382.1 - 0.44 10.4 2.3 5.1 7.0 0.0 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat S1 PF00575.18 EDP44383.1 - 5.6e-45 151.3 14.2 4.4e-14 52.3 0.2 10.3 8 2 1 9 9 9 7 S1 RNA binding domain Peptidase_M28 PF04389.12 EDP44384.1 - 8.7e-27 94.0 0.0 1.6e-25 89.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDP44384.1 - 2.1e-08 33.9 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 EF-hand_6 PF13405.1 EDP44384.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DNA_pol_B_palm PF14792.1 EDP44386.1 - 3.1e-16 59.4 0.1 5.7e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EDP44386.1 - 8e-12 45.1 0.0 8.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EDP44386.1 - 1.8e-07 31.2 0.0 0.00048 20.2 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EDP44386.1 - 1.2e-06 28.0 0.1 3.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EDP44386.1 - 2e-06 27.2 0.0 7.4e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EDP44386.1 - 0.00043 20.5 0.1 0.00084 19.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH PF00633.18 EDP44386.1 - 0.022 14.4 0.0 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Aminotran_1_2 PF00155.16 EDP44387.1 - 3e-91 306.0 0.0 3.5e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Rav1p_C PF12234.3 EDP44388.1 - 4e-87 292.8 1.3 1e-79 268.4 0.1 2.2 2 0 0 2 2 2 2 RAVE protein 1 C terminal DUF2305 PF10230.4 EDP44389.1 - 1e-30 107.0 0.0 1.2e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EDP44389.1 - 8.2e-14 52.0 0.6 1e-13 51.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44389.1 - 2.8e-07 30.3 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP44389.1 - 4.4e-05 23.2 0.0 5.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDP44389.1 - 0.00063 19.4 0.3 0.0021 17.6 0.2 1.9 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EDP44389.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EDP44389.1 - 0.0081 16.4 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.3 EDP44389.1 - 0.063 12.4 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PE-PPE PF08237.6 EDP44389.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Sec3-PIP2_bind PF15277.1 EDP44390.1 - 6.9e-13 48.2 0.0 9.6e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EDP44391.1 - 1.1e-136 456.8 0.8 9.9e-136 453.6 0.5 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.7 EDP44391.1 - 0.22 9.9 4.4 1 7.7 1.5 2.7 3 0 0 3 3 3 0 Vps52 / Sac2 family K_oxygenase PF13434.1 EDP44392.1 - 3.7e-93 312.1 0.0 1.5e-92 310.1 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDP44392.1 - 1.7e-08 34.4 0.0 3.9e-07 29.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDP44392.1 - 7.5e-08 32.6 0.0 3.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Prok-E2_E PF14462.1 EDP44392.1 - 0.13 11.8 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family E Acetyltransf_8 PF13523.1 EDP44393.1 - 1.2e-46 158.3 0.1 1.8e-46 157.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDP44393.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DcpS_C PF11969.3 EDP44395.1 - 1.1e-09 38.4 6.5 8.4e-09 35.6 4.5 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EDP44395.1 - 2.5e-08 34.3 2.5 5.4e-07 30.0 1.7 2.2 1 1 0 1 1 1 1 HIT domain CS PF04969.11 EDP44396.1 - 1.2e-09 38.5 0.0 5.8e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 CS domain DUF2388 PF09498.5 EDP44396.1 - 0.02 14.4 0.5 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Cwf_Cwc_15 PF04889.7 EDP44397.1 - 0.023 14.4 1.8 0.053 13.2 1.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HA2 PF04408.18 EDP44398.1 - 5e-17 61.7 0.0 5e-17 61.7 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP44398.1 - 1.4e-11 44.1 0.2 3.5e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDP44398.1 - 3.2e-08 33.3 0.0 1.5e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EDP44398.1 - 2.2e-07 31.0 0.3 3.2e-06 27.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 EDP44398.1 - 0.0092 15.1 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 1 KaiC UBA PF00627.26 EDP44398.1 - 0.012 15.4 0.0 0.043 13.6 0.0 2.1 1 0 0 1 1 1 0 UBA/TS-N domain ABC_tran PF00005.22 EDP44398.1 - 0.067 13.4 1.3 0.2 11.9 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 EDP44398.1 - 0.079 12.5 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EDP44398.1 - 0.36 11.1 2.4 10 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhzC-PhzF PF02567.11 EDP44399.1 - 5.5e-54 183.2 0.0 6.3e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EDP44399.1 - 0.071 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Proline racemase AA_permease_2 PF13520.1 EDP44400.1 - 2.9e-71 240.2 33.4 2.9e-71 240.2 23.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDP44400.1 - 1.2e-20 73.3 29.3 1.9e-20 72.6 20.3 1.2 1 0 0 1 1 1 1 Amino acid permease OppC_N PF12911.2 EDP44400.1 - 0.48 9.8 7.6 7 6.1 0.1 3.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Homeobox PF00046.24 EDP44401.1 - 1.1e-06 28.1 2.9 8.9e-06 25.2 2.0 2.3 1 1 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDP44402.1 - 1.2e-17 63.3 1.0 2.8e-17 62.1 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.7 EDP44402.1 - 0.0015 17.9 0.3 0.0034 16.7 0.2 1.6 1 1 0 1 1 1 1 Ustilago B locus mating-type protein Mating_N PF12731.2 EDP44402.1 - 0.01 15.6 1.3 0.021 14.7 0.9 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Homeobox PF00046.24 EDP44402.1 - 0.032 13.8 0.1 0.097 12.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox domain Sas10_Utp3 PF04000.10 EDP44403.1 - 4.2e-11 42.8 0.1 1.3e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 Sas10/Utp3/C1D family Glu-tRNAGln PF02686.10 EDP44403.1 - 0.13 12.0 0.7 10 6.0 0.1 2.8 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Lung_7-TM_R PF06814.8 EDP44405.1 - 3.9e-51 173.7 23.7 9e-51 172.5 16.4 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF1279 PF06916.8 EDP44405.1 - 4 7.8 8.4 1.2 9.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) UPF0233 PF06781.7 EDP44405.1 - 4.6 6.9 6.6 0.36 10.4 0.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) CWC25 PF12542.3 EDP44406.1 - 1.8e-24 86.0 1.1 1.8e-24 86.0 0.8 3.9 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EDP44406.1 - 8.4e-14 51.3 15.0 8.4e-14 51.3 10.4 3.2 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR RNA_pol_Rpb2_6 PF00562.23 EDP44407.1 - 1.9e-124 415.3 0.8 2.2e-124 415.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDP44407.1 - 1.5e-64 216.6 0.0 2.5e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDP44407.1 - 2.3e-48 164.1 0.0 4.2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDP44407.1 - 1.7e-27 95.5 0.1 4.4e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDP44407.1 - 1.9e-26 91.6 0.2 5.9e-26 90.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDP44407.1 - 2.3e-23 81.7 0.1 4.5e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDP44407.1 - 1.2e-19 70.0 0.2 2.8e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Nop25 PF09805.4 EDP44409.1 - 0.0021 18.1 0.4 0.0021 18.1 0.3 1.7 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) KAR9 PF08580.5 EDP44409.1 - 0.053 11.7 3.9 0.062 11.5 2.7 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1767 PF08585.7 EDP44410.1 - 0.0055 16.9 1.0 0.024 14.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1767) 2-oxoacid_dh PF00198.18 EDP44411.1 - 2.8e-80 268.8 0.3 4.2e-80 268.3 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDP44411.1 - 9.5e-19 66.8 0.4 2.4e-18 65.5 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDP44411.1 - 6.6e-14 51.2 0.2 1.4e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain DUF1675 PF07897.6 EDP44411.1 - 0.0049 16.7 3.3 0.0086 15.9 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) Tim54 PF11711.3 EDP44411.1 - 0.12 10.9 2.5 0.21 10.1 1.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 WES_acyltransf PF03007.11 EDP44412.1 - 2.8e-16 59.8 0.1 6.2e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 EDP44412.1 - 3.2e-05 23.7 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) AATase PF07247.7 EDP44412.1 - 0.13 10.8 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase LTV PF04180.9 EDP44413.1 - 1.3e-12 47.9 7.4 1.3e-12 47.9 5.1 3.2 2 2 1 3 3 3 1 Low temperature viability protein TraH_2 PF06871.6 EDP44413.1 - 0.59 9.5 0.0 0.59 9.5 0.0 3.0 3 1 1 4 4 4 0 TraH_2 EXOSC1 PF10447.4 EDP44414.1 - 4.4e-29 100.2 0.1 6.2e-29 99.7 0.0 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EDP44414.1 - 0.016 15.3 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 S1 RNA binding domain ECR1_N PF14382.1 EDP44414.1 - 0.036 13.3 0.4 0.51 9.6 0.0 2.8 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region PPR_3 PF13812.1 EDP44415.1 - 2.8e-06 27.1 4.0 3.8 8.0 0.0 6.9 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDP44415.1 - 4.9e-06 26.4 0.0 0.013 15.4 0.0 5.0 5 0 0 5 5 5 1 PPR repeat family MoeZ_MoeB PF05237.8 EDP44415.1 - 0.032 13.8 0.3 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 MoeZ/MoeB domain PPR_1 PF12854.2 EDP44415.1 - 0.063 12.7 1.3 3 7.4 0.0 3.9 4 0 0 4 4 4 0 PPR repeat GATA PF00320.22 EDP44416.1 - 3e-14 52.0 5.1 5.9e-14 51.1 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger PsiF_repeat PF07769.9 EDP44416.1 - 0.06 12.8 0.6 0.14 11.6 0.4 1.6 1 0 0 1 1 1 0 psiF repeat Peptidase_M18 PF02127.10 EDP44417.1 - 3e-129 431.2 0.0 3.6e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) UCH PF00443.24 EDP44418.1 - 2.6e-29 102.1 0.0 3.1e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP44418.1 - 0.044 13.2 0.0 0.051 13.0 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 EDP44419.1 - 2e-35 122.1 14.4 3e-35 121.6 9.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EDP44420.1 - 2e-32 112.2 14.0 2.8e-32 111.8 9.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PLAC8 PF04749.12 EDP44420.1 - 0.65 10.5 4.5 0.67 10.5 1.1 2.6 2 1 1 3 3 3 0 PLAC8 family 4HBT PF03061.17 EDP44421.1 - 1.3e-06 28.4 0.1 2.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acatn PF13000.2 EDP44422.1 - 2.7e-133 445.4 30.4 7.5e-65 219.4 8.9 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Iso_dh PF00180.15 EDP44423.1 - 3.6e-119 397.8 0.0 4.1e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PSCyt3 PF07627.6 EDP44424.1 - 0.045 13.6 0.8 13 5.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Cation_efflux PF01545.16 EDP44425.1 - 2.2e-16 59.7 0.5 2.7e-16 59.4 0.3 1.0 1 0 0 1 1 1 1 Cation efflux family 60KD_IMP PF02096.15 EDP44425.1 - 0.22 11.1 1.6 1.3 8.6 1.1 1.9 1 1 0 1 1 1 0 60Kd inner membrane protein TPR_2 PF07719.12 EDP44426.1 - 2.8e-07 29.9 4.5 0.017 14.9 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44426.1 - 4.9e-07 29.6 7.1 0.0036 17.1 0.1 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDP44426.1 - 3.1e-06 26.7 2.7 0.47 10.1 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 EDP44426.1 - 6.2e-05 22.4 0.1 0.026 14.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44426.1 - 0.00064 19.3 5.8 0.59 10.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDP44426.1 - 0.0044 17.1 0.3 0.33 11.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EDP44426.1 - 0.007 16.2 3.4 1.1 9.2 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44426.1 - 0.055 13.6 0.0 1.8 8.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44426.1 - 0.079 13.4 3.9 0.18 12.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44426.1 - 0.08 12.7 0.0 11 6.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44426.1 - 0.2 12.3 12.9 2.1 9.1 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44426.1 - 9.1 7.2 13.4 4.8 8.0 0.3 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat ATP_bind_3 PF01171.15 EDP44427.1 - 8.9e-16 57.9 0.0 1.5e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EDP44427.1 - 0.00098 17.7 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 EDP44427.1 - 0.014 14.7 0.3 0.014 14.7 0.2 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding RecR PF02132.10 EDP44427.1 - 0.02 14.2 1.4 0.02 14.2 0.9 2.6 3 0 0 3 3 3 0 RecR protein Asn_synthase PF00733.16 EDP44427.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase TGS PF02824.16 EDP44428.1 - 3.4e-20 71.6 0.0 6e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDP44428.1 - 1.4e-17 63.6 0.1 3.4e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP44428.1 - 4.8e-09 35.6 0.1 1.4e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EDP44428.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EDP44428.1 - 0.042 13.6 0.4 1.1 9.0 0.0 2.2 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 EDP44428.1 - 0.052 12.9 0.2 6.7 6.1 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 EDP44428.1 - 0.19 10.4 2.8 0.11 11.2 0.4 1.7 2 0 0 2 2 2 0 ArgK protein CBS PF00571.23 EDP44429.1 - 1.3e-07 31.2 0.5 0.012 15.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF21 PF01595.15 EDP44429.1 - 0.006 15.9 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 DUF221 PF02714.10 EDP44430.1 - 3.2e-78 262.8 17.5 3.2e-78 262.8 12.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDP44430.1 - 9.8e-37 125.9 2.3 9.8e-37 125.9 1.6 3.4 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDP44430.1 - 1.4e-20 73.5 0.9 2.6e-20 72.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EDP44430.1 - 2.5e-12 46.5 0.0 7.1e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein Amnionless PF14828.1 EDP44430.1 - 0.2 10.1 0.1 9 4.6 0.0 2.2 2 0 0 2 2 2 0 Amnionless Vma12 PF11712.3 EDP44430.1 - 0.39 10.4 4.4 1 9.0 3.1 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase adh_short PF00106.20 EDP44431.1 - 9.1e-27 94.0 3.8 1.4e-26 93.3 0.7 2.5 2 1 0 2 2 2 1 short chain dehydrogenase DUF2470 PF10615.4 EDP44431.1 - 5.4e-15 55.3 1.9 1.1e-14 54.4 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) KR PF08659.5 EDP44431.1 - 3.5e-10 39.8 4.4 1.3e-08 34.6 0.4 3.5 3 1 0 3 3 3 1 KR domain adh_short_C2 PF13561.1 EDP44431.1 - 7.3e-07 29.1 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDP44431.1 - 0.00092 19.2 0.1 0.0035 17.3 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDP44431.1 - 0.0067 15.8 0.1 0.019 14.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AhpC-TSA PF00578.16 EDP44432.1 - 1.8e-33 114.8 0.0 2.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDP44432.1 - 5.1e-13 48.7 0.0 6.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDP44432.1 - 5.1e-12 45.2 0.0 8.7e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF883 PF05957.8 EDP44433.1 - 0.00021 21.6 11.2 0.023 15.0 2.4 3.3 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Apo-CIII PF05778.7 EDP44433.1 - 0.00084 18.6 6.0 0.0095 15.3 0.0 3.4 3 1 0 3 3 3 1 Apolipoprotein CIII (Apo-CIII) YtxH PF12732.2 EDP44433.1 - 0.0015 18.8 15.3 0.17 12.2 2.7 3.4 1 1 2 3 3 3 3 YtxH-like protein ApoA-II PF04711.8 EDP44433.1 - 0.0038 17.0 1.1 0.0038 17.0 0.8 1.9 2 0 0 2 2 2 1 Apolipoprotein A-II (ApoA-II) PHTB1_C PF14728.1 EDP44433.1 - 0.021 13.6 0.3 0.027 13.2 0.2 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus Apolipoprotein PF01442.13 EDP44433.1 - 0.033 13.7 8.6 0.1 12.1 5.7 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 EDP44433.1 - 0.07 10.6 4.9 0.1 10.1 3.4 1.2 1 1 0 1 1 1 0 Prominin KMP11 PF03037.11 EDP44433.1 - 0.18 12.4 3.4 6.6 7.3 2.3 2.2 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1635 PF07795.6 EDP44433.1 - 0.19 11.0 3.0 0.22 10.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Fib_alpha PF08702.5 EDP44433.1 - 0.25 11.4 4.9 0.12 12.4 1.1 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2563 PF10817.3 EDP44433.1 - 0.26 11.7 7.1 0.97 9.8 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2563) ApoLp-III PF07464.6 EDP44433.1 - 0.27 11.2 13.8 6 6.8 2.6 2.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) KBP_C PF12309.3 EDP44433.1 - 0.54 9.1 6.6 0.32 9.9 1.8 1.9 1 1 1 2 2 2 0 KIF-1 binding protein C terminal Mnd1 PF03962.10 EDP44433.1 - 0.64 9.6 10.0 0.6 9.7 6.2 1.3 2 0 0 2 2 1 0 Mnd1 family Na_trans_assoc PF06512.8 EDP44433.1 - 0.82 9.6 4.8 1 9.3 3.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Tape_meas_lam_C PF09718.5 EDP44433.1 - 1 9.3 19.5 0.3 11.0 1.8 3.9 2 1 1 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3584 PF12128.3 EDP44433.1 - 1.3 6.2 11.9 1.6 5.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EDP44433.1 - 1.5 7.7 6.4 1.8 7.4 4.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_B PF00430.13 EDP44433.1 - 1.7 8.4 18.8 0.14 11.9 6.8 2.5 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) MT0933_antitox PF14013.1 EDP44433.1 - 2.5 8.2 10.7 2.5 8.2 0.3 3.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein DUF148 PF02520.12 EDP44433.1 - 2.8 7.7 10.2 10 5.9 4.9 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 Chorismate_bind PF00425.13 EDP44434.1 - 2.1e-75 253.3 0.0 2.9e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EDP44434.1 - 2.1e-09 37.4 0.0 6e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Pro_isomerase PF00160.16 EDP44435.1 - 0.001 19.2 0.0 0.011 15.9 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF498 PF04430.9 EDP44436.1 - 1.8e-16 59.6 0.0 2.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Nop52 PF05997.7 EDP44437.1 - 0.0081 15.6 0.5 0.014 14.8 0.1 1.5 2 0 0 2 2 2 1 Nucleolar protein,Nop52 RNA_pol_A_bac PF01000.21 EDP44438.1 - 2.7e-18 66.1 0.0 9.1e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDP44438.1 - 0.0032 16.5 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1752 PF08550.5 EDP44439.1 - 6.8e-11 41.5 3.9 1.5e-10 40.4 2.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3052 PF11253.3 EDP44439.1 - 0.14 11.7 0.9 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) DUF1620 PF07774.8 EDP44441.1 - 2.3e-43 147.9 0.0 3.7e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EDP44441.1 - 0.0022 17.4 2.1 0.006 16.0 0.2 2.6 3 0 0 3 3 3 1 PQQ-like domain NgoMIV_restric PF09015.5 EDP44441.1 - 0.067 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 NgoMIV restriction enzyme PQQ PF01011.16 EDP44441.1 - 0.11 12.0 1.0 4.1 7.1 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Cofilin_ADF PF00241.15 EDP44442.1 - 5.8e-16 58.5 0.0 7.1e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 EDP44443.1 - 9.2e-10 38.0 0.3 0.00023 20.9 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.2 EDP44443.1 - 2e-08 33.7 0.2 5e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDP44443.1 - 7.1e-06 25.5 0.1 1.8e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 EDP44443.1 - 0.16 11.6 10.0 0.15 11.7 1.3 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Noc2 PF03715.8 EDP44444.1 - 4e-101 337.8 0.1 5.9e-101 337.2 0.1 1.2 1 0 0 1 1 1 1 Noc2p family UCH PF00443.24 EDP44445.1 - 1.2e-45 155.6 0.0 1.5e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP44445.1 - 4.4e-20 72.2 0.0 7.5e-20 71.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EDP44445.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family zf-C2H2 PF00096.21 EDP44446.1 - 5.9e-08 32.6 15.5 0.0001 22.3 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDP44446.1 - 2e-07 30.9 3.8 2e-07 30.9 2.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDP44446.1 - 3e-06 27.1 11.1 0.00066 19.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDP44446.1 - 3.3 7.9 8.5 7 6.9 2.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CUE PF02845.11 EDP44447.1 - 1e-07 31.3 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 EDP44447.1 - 0.00029 20.4 0.2 0.00096 18.7 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 RR_TM4-6 PF06459.7 EDP44447.1 - 6 6.6 16.8 0.42 10.4 7.7 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DSPc PF00782.15 EDP44448.1 - 1e-29 102.8 0.0 2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EDP44448.1 - 0.00017 21.8 0.0 0.039 14.2 0.0 2.8 2 1 0 2 2 2 2 Rhodanese-like domain Y_phosphatase2 PF03162.8 EDP44448.1 - 0.0045 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family B-block_TFIIIC PF04182.7 EDP44449.1 - 3.6e-08 33.1 0.0 7.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EDP44449.1 - 0.0017 18.0 3.4 0.023 14.3 0.0 3.5 4 0 0 4 4 4 1 MarR family HTH_20 PF12840.2 EDP44449.1 - 0.009 15.8 0.1 0.31 10.8 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain Semialdhyde_dh PF01118.19 EDP44449.1 - 0.036 14.3 0.1 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HTH_27 PF13463.1 EDP44449.1 - 0.063 13.6 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain PAP_assoc PF03828.14 EDP44450.1 - 3.7e-18 65.2 0.1 7.1e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDP44450.1 - 4.3e-05 23.7 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2392 PF10288.4 EDP44452.1 - 6.8e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Pkinase PF00069.20 EDP44453.1 - 3.9e-71 239.2 0.0 5.7e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44453.1 - 1.1e-38 132.7 0.0 2.7e-38 131.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44453.1 - 8e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EDP44453.1 - 0.00076 18.8 0.2 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EDP44453.1 - 0.0019 18.0 0.1 0.0055 16.4 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family KA1 PF02149.14 EDP44454.1 - 0.00033 20.0 0.1 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Mito_carr PF00153.22 EDP44455.1 - 3e-45 151.8 0.3 1.1e-21 76.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.22 EDP44456.1 - 3.1e-21 74.8 0.0 3.6e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Aa_trans PF01490.13 EDP44457.1 - 6.5e-21 74.2 37.9 1e-20 73.6 26.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Sec1 PF00995.18 EDP44458.1 - 1.6e-133 446.3 0.0 1.8e-133 446.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pex14_N PF04695.8 EDP44459.1 - 9e-30 103.4 0.0 9e-30 103.4 0.0 3.8 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EDP44459.1 - 0.0016 18.0 2.2 0.0029 17.2 1.5 1.4 1 0 0 1 1 1 1 IncA protein DUF4631 PF15450.1 EDP44459.1 - 0.018 13.3 6.0 0.024 12.9 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) LXG PF04740.7 EDP44459.1 - 0.04 13.7 3.8 0.059 13.1 2.6 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF3584 PF12128.3 EDP44459.1 - 0.041 11.2 8.1 0.052 10.8 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4200 PF13863.1 EDP44459.1 - 0.05 13.5 6.6 0.087 12.7 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Methyltransf_14 PF08484.6 EDP44459.1 - 0.12 11.9 0.6 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Nup88 PF10168.4 EDP44459.1 - 0.17 9.6 3.3 0.23 9.2 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component AAA_13 PF13166.1 EDP44459.1 - 0.2 10.0 1.7 0.27 9.6 1.2 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EDP44459.1 - 0.32 10.0 5.9 1.5 7.7 4.6 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2576 PF10845.3 EDP44459.1 - 0.5 9.5 1.6 0.57 9.3 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF1664 PF07889.7 EDP44459.1 - 0.74 9.6 4.0 1.9 8.2 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.7 EDP44459.1 - 0.76 10.1 7.4 0.69 10.3 1.6 2.7 2 1 1 3 3 2 0 SlyX ATP-synt_B PF00430.13 EDP44459.1 - 1.2 8.9 6.7 1.9 8.3 4.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CENP-Q PF13094.1 EDP44459.1 - 1.4 8.9 9.2 2.1 8.3 6.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EDP44459.1 - 1.4 7.7 6.5 2 7.2 4.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 EDP44459.1 - 1.6 7.7 3.5 2.2 7.2 2.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.1 EDP44459.1 - 1.6 7.8 7.1 0.5 9.5 0.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.4 EDP44459.1 - 4.4 7.2 6.0 3.2 7.7 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA FlgN PF05130.7 EDP44459.1 - 5.4 7.2 12.0 7.8 6.7 7.4 1.7 1 1 0 1 1 1 0 FlgN protein Herpes_capsid PF06112.6 EDP44459.1 - 6.4 6.8 9.7 18 5.3 6.8 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RNA_pol_L_2 PF13656.1 EDP44460.1 - 7.3e-26 89.4 0.0 9.8e-26 89.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDP44460.1 - 2.9e-14 51.9 0.0 4.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEC-1_C PF04626.8 EDP44460.1 - 0.6 10.2 2.9 0.97 9.6 2.0 1.3 1 0 0 1 1 1 0 Dec-1 protein, C terminal region RRM_1 PF00076.17 EDP44461.1 - 9.8e-39 130.8 0.0 6.4e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44461.1 - 1.5e-33 114.5 0.1 5.4e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44461.1 - 3.2e-14 52.4 0.0 2.7e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 EDP44462.1 - 2.3 7.9 10.8 3.3 7.4 7.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Membr_traf_MHD PF10540.4 EDP44463.1 - 4.5e-18 65.3 0.1 1.6e-17 63.5 0.1 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EDP44463.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Rft-1 PF04506.8 EDP44464.1 - 1.6e-53 181.9 0.0 3.1e-52 177.7 0.0 2.1 1 1 0 1 1 1 1 Rft protein ATXN-1_C PF12547.3 EDP44464.1 - 0.13 12.2 0.3 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Mid1 PF12929.2 EDP44466.1 - 1.2e-78 264.7 5.3 1e-77 261.6 3.7 1.9 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component fn3 PF00041.16 EDP44466.1 - 0.0018 18.3 0.2 0.0042 17.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Fz PF01392.17 EDP44466.1 - 0.019 15.3 3.1 0.21 11.9 0.2 2.4 2 0 0 2 2 2 0 Fz domain Ras_bdg_2 PF14847.1 EDP44466.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Pkinase PF00069.20 EDP44467.1 - 7.6e-71 238.2 0.0 9.2e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44467.1 - 1.1e-31 109.9 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDP44467.1 - 0.00013 21.1 0.0 0.00039 19.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP44467.1 - 0.00086 19.1 0.1 0.0023 17.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP44467.1 - 0.0066 15.4 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EDP44467.1 - 0.05 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FCH PF00611.18 EDP44468.1 - 1.2e-10 41.4 1.0 2.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Zip PF02535.17 EDP44468.1 - 0.27 10.1 1.2 0.4 9.6 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EDP44468.1 - 3.3 7.0 12.2 8.2 5.7 8.4 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region muHD PF10291.4 EDP44469.1 - 2.2e-17 63.1 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain HIG_1_N PF04588.8 EDP44470.1 - 0.0074 16.0 3.3 0.011 15.4 2.3 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3485 PF11984.3 EDP44470.1 - 0.022 13.8 0.4 0.039 13.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3485) Hep_59 PF07052.6 EDP44470.1 - 0.032 14.5 0.7 0.053 13.8 0.5 1.3 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF4407 PF14362.1 EDP44470.1 - 2.8 6.7 8.0 4 6.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VHS PF00790.14 EDP44471.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 VHS domain Pkinase PF00069.20 EDP44472.1 - 3.1e-32 111.7 0.0 5.5e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44472.1 - 9.2e-14 51.1 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44472.1 - 0.00031 19.7 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP44472.1 - 0.0049 15.9 0.0 0.0095 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP44472.1 - 0.0063 16.2 0.3 0.016 14.9 0.0 1.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDP44472.1 - 0.046 13.2 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Med3 PF11593.3 EDP44472.1 - 1.1 8.4 14.7 1.7 7.7 10.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 EDP44472.1 - 2 6.0 13.4 2.9 5.5 9.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIG-L PF02585.12 EDP44473.1 - 1.2e-23 84.0 0.0 1.9e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PEMT PF04191.8 EDP44474.1 - 7.2e-32 109.6 4.5 7.2e-32 109.6 3.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase PCI PF01399.22 EDP44475.1 - 3.3e-15 56.2 0.0 1.5e-14 54.2 0.0 2.1 3 0 0 3 3 3 1 PCI domain ALO PF04030.9 EDP44476.1 - 1.9e-58 198.1 0.6 6.2e-58 196.4 0.2 1.9 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EDP44476.1 - 4.2e-18 65.1 0.0 8.3e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thioredoxin PF00085.15 EDP44477.1 - 3.3e-56 187.3 0.1 1.1e-28 99.0 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EDP44477.1 - 5.2e-42 143.7 1.3 9.3e-32 110.3 0.1 3.5 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDP44477.1 - 6.4e-12 45.4 0.3 0.05 13.7 0.0 4.8 5 2 0 5 5 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 EDP44477.1 - 9e-09 35.2 0.0 0.015 15.3 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDP44477.1 - 1.1e-08 35.2 2.9 0.1 12.7 0.0 4.7 3 3 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 EDP44477.1 - 5.4e-06 26.0 0.9 0.58 9.8 0.0 4.1 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 EDP44477.1 - 0.00044 19.8 0.8 1 8.9 0.0 3.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 EDP44477.1 - 0.0018 18.3 0.2 1.1 9.2 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 EDP44477.1 - 0.0047 16.4 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Calsequestrin PF01216.12 EDP44477.1 - 0.082 11.6 1.4 0.11 11.1 0.3 1.7 2 0 0 2 2 2 0 Calsequestrin HyaE PF07449.6 EDP44477.1 - 0.091 12.6 0.0 18 5.2 0.0 3.1 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Mu-like_Com PF10122.4 EDP44477.1 - 0.33 10.0 0.8 5 6.2 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com RhoGEF PF00621.15 EDP44478.1 - 1.5e-41 142.2 1.2 2.7e-41 141.4 0.4 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 EDP44478.1 - 5.8e-29 100.6 0.0 2.2e-28 98.7 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EDP44478.1 - 3e-24 84.9 0.0 5.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EDP44478.1 - 1.7e-08 33.9 0.0 3.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EDP44478.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Gp_dh_C PF02800.15 EDP44479.1 - 7.4e-75 249.6 0.0 1.1e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EDP44479.1 - 1.6e-57 193.6 0.0 3.3e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EDP44479.1 - 0.059 13.2 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNase_PH PF01138.16 EDP44480.1 - 2.7e-14 53.6 0.0 4.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1116 PF06545.6 EDP44480.1 - 0.0049 15.9 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) RNase_PH_C PF03725.10 EDP44480.1 - 0.065 13.1 0.4 0.17 11.8 0.0 2.0 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 APO_RNA-bind PF05634.6 EDP44480.1 - 0.13 11.4 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 APO RNA-binding STE3 PF02076.10 EDP44482.1 - 2.4e-77 259.8 12.1 2.4e-77 259.8 8.4 1.3 2 0 0 2 2 2 1 Pheromone A receptor VWA_2 PF13519.1 EDP44483.1 - 1.1e-07 32.0 0.5 2.2e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 EDP44483.1 - 2.6e-06 26.4 22.3 0.0027 17.1 1.6 4.5 4 0 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.9 EDP44483.1 - 0.0039 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like MitMem_reg PF13012.1 EDP44483.1 - 0.042 13.9 0.2 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function CAF1 PF04857.15 EDP44484.1 - 5.9e-60 202.8 0.0 8.5e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease UQ_con PF00179.21 EDP44485.1 - 1.7e-45 153.8 0.0 2e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDP44485.1 - 0.02 14.6 0.1 0.069 12.9 0.1 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Njmu-R1 PF15053.1 EDP44486.1 - 0.093 11.4 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Mjmu-R1-like protein family GTP_EFTU PF00009.22 EDP44487.1 - 1.5e-34 119.0 0.8 1.5e-34 119.0 0.5 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDP44487.1 - 4.9e-23 81.1 0.1 3.2e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDP44487.1 - 2.4e-11 43.5 0.2 8.7e-05 22.5 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDP44487.1 - 1.2e-05 25.2 0.1 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDP44487.1 - 7.9e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EDP44487.1 - 0.00036 19.8 0.0 0.001 18.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EDP44487.1 - 0.0014 18.1 0.2 0.024 14.1 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EDP44487.1 - 0.0027 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDP44487.1 - 0.0037 16.6 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDP44487.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Prefoldin PF02996.12 EDP44488.1 - 1e-29 102.6 0.2 1.3e-29 102.2 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit HVSL PF09749.4 EDP44488.1 - 0.051 12.6 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein BCAS3 PF12490.3 EDP44488.1 - 0.076 12.3 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Ribosomal_L28e PF01778.12 EDP44489.1 - 9e-36 122.8 0.3 1.1e-35 122.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF3128 PF11326.3 EDP44491.1 - 4e-22 78.1 0.6 5.7e-22 77.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) PAS_7 PF12860.2 EDP44491.1 - 0.032 14.2 0.0 0.12 12.3 0.0 1.8 1 1 1 2 2 2 0 PAS fold RNA_pol_Rpb2_6 PF00562.23 EDP44492.1 - 7e-120 400.3 0.3 1.3e-119 399.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDP44492.1 - 3.7e-57 192.5 0.3 6.8e-57 191.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDP44492.1 - 7.4e-37 126.6 0.8 1.7e-36 125.4 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDP44492.1 - 2e-27 95.2 0.1 4.9e-27 94.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDP44492.1 - 3.2e-23 81.3 0.4 2.7e-22 78.3 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDP44492.1 - 1.9e-21 75.5 0.0 4.3e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDP44492.1 - 2.5e-11 43.3 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NIF3 PF01784.13 EDP44493.1 - 2.5e-55 187.6 0.0 3.4e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Hydrolase_like PF13242.1 EDP44493.1 - 0.047 13.4 0.1 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DUF89 PF01937.14 EDP44494.1 - 1.4e-107 359.6 0.0 1.6e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Bap31 PF05529.7 EDP44495.1 - 2.8e-23 82.3 3.1 3.7e-23 81.9 2.1 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like OmpH PF03938.9 EDP44495.1 - 0.0064 16.4 1.8 0.0064 16.4 1.3 1.8 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF3450 PF11932.3 EDP44495.1 - 0.011 14.9 0.6 0.013 14.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.6 EDP44495.1 - 0.012 15.4 2.3 0.018 14.9 1.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GPO PF05929.6 EDP44495.1 - 0.013 14.7 1.3 0.012 14.8 0.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.1 EDP44495.1 - 0.021 13.7 0.4 0.021 13.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-bind_6 PF13921.1 EDP44495.1 - 0.029 14.4 1.7 0.053 13.6 0.6 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Atg14 PF10186.4 EDP44495.1 - 0.035 13.0 0.7 0.039 12.8 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 EDP44495.1 - 0.17 12.2 4.5 3.5 7.9 2.5 2.5 1 1 1 2 2 2 0 Snapin/Pallidin FliD_N PF02465.13 EDP44495.1 - 0.2 12.0 4.4 0.51 10.7 3.0 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.10 EDP44495.1 - 0.48 9.9 5.4 0.94 9.0 3.8 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EDP44495.1 - 1.9 8.0 6.4 2.1 7.8 4.5 1.4 1 1 0 1 1 1 0 IncA protein MT-A70 PF05063.9 EDP44496.1 - 1.4e-39 135.5 0.0 1.9e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Mg_trans_NIPA PF05653.9 EDP44497.1 - 2.5e-61 207.2 7.5 3.5e-61 206.7 5.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EDP44497.1 - 4e-05 23.6 25.6 0.0024 17.9 3.2 3.3 2 1 1 3 3 3 2 EamA-like transporter family DUF1301 PF06979.7 EDP44497.1 - 0.088 12.9 3.5 0.23 11.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) Bacteriocin_IId PF09221.5 EDP44497.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.0 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Oxidored_q6 PF01058.17 EDP44497.1 - 0.16 11.6 0.3 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Pyr_redox_dim PF02852.17 EDP44498.1 - 2.7e-42 143.2 0.7 9.3e-42 141.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EDP44498.1 - 1.4e-38 132.8 13.9 1.2e-36 126.4 9.6 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDP44498.1 - 3.6e-21 75.3 11.3 1.1e-19 70.5 0.5 3.8 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDP44498.1 - 2.9e-13 49.7 7.5 2.4e-11 43.4 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EDP44498.1 - 1.9e-11 43.4 2.8 2.4e-09 36.5 0.4 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDP44498.1 - 3.6e-11 43.5 1.1 6.1e-06 26.4 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP44498.1 - 2e-10 40.5 2.3 0.0002 21.2 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDP44498.1 - 6.1e-09 34.8 12.3 9.1e-05 21.0 0.7 4.2 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_3 PF01494.14 EDP44498.1 - 2.6e-07 30.0 10.9 0.03 13.3 0.7 3.3 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 EDP44498.1 - 8.8e-07 28.1 2.2 8.8e-07 28.1 1.5 3.5 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EDP44498.1 - 3.2e-06 26.4 9.0 0.00019 20.6 1.0 2.6 1 1 1 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.16 EDP44498.1 - 4.2e-06 26.4 2.5 0.0089 15.6 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EDP44498.1 - 8.9e-06 24.8 14.8 0.16 10.8 0.0 3.8 2 2 2 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EDP44498.1 - 4.7e-05 22.4 2.1 0.1 11.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EDP44498.1 - 0.0092 15.0 0.1 0.078 12.0 0.0 2.3 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EDP44498.1 - 0.3 11.3 2.7 1.3 9.3 0.1 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EDP44498.1 - 1 8.1 7.7 0.91 8.3 0.4 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EDP44498.1 - 1.6 8.3 6.3 0.13 11.9 0.2 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos PF00149.23 EDP44499.1 - 1.2e-42 145.5 0.0 1.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.10 EDP44500.1 - 1.6e-08 34.2 0.1 2.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDP44500.1 - 2.6e-05 24.3 0.1 5.9e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.17 EDP44501.1 - 4.2e-13 48.7 0.0 6.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44501.1 - 1.1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44501.1 - 4.9e-06 26.2 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP44501.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CTP_transf_2 PF01467.21 EDP44502.1 - 2.1e-17 63.5 0.0 3.3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase LIM PF00412.17 EDP44503.1 - 6.3e-15 54.9 18.0 5.1e-08 32.8 3.3 2.4 2 1 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.1 EDP44503.1 - 0.4 10.2 0.1 0.4 10.2 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain PCI PF01399.22 EDP44505.1 - 2.2e-23 82.5 0.4 8.3e-23 80.7 0.3 2.1 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EDP44505.1 - 7.5e-23 80.7 0.9 1.9e-22 79.4 0.7 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EDP44505.1 - 0.063 13.2 0.1 0.8 9.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TLV_coat PF00429.14 EDP44505.1 - 0.067 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) RRM_1 PF00076.17 EDP44506.1 - 1.4e-73 242.5 0.0 7e-18 64.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44506.1 - 1.9e-65 216.7 0.4 1.3e-15 57.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44506.1 - 3.2e-36 122.9 0.0 1.1e-06 28.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EDP44506.1 - 0.00046 20.1 0.0 0.078 12.9 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 EDP44506.1 - 0.00059 19.5 0.0 3.4 7.5 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EDP44506.1 - 0.02 14.6 0.4 1.6 8.5 0.0 3.6 3 1 1 4 4 4 0 Limkain b1 Mito_carr PF00153.22 EDP44508.1 - 8.4e-53 176.0 2.0 2e-24 85.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMG_box PF00505.14 EDP44509.1 - 2.1e-18 66.3 0.6 3.3e-18 65.7 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDP44509.1 - 1.4e-15 57.3 1.3 2.1e-15 56.8 0.9 1.2 1 0 0 1 1 1 1 HMG-box domain LSM PF01423.17 EDP44510.1 - 2.4e-12 46.2 0.1 3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDP44510.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Proteasome PF00227.21 EDP44511.1 - 5.5e-60 201.9 0.1 7.5e-60 201.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDP44511.1 - 2.6e-15 55.4 0.3 6.4e-15 54.1 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GST_N PF02798.15 EDP44512.1 - 1e-13 51.2 0.0 1.1e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDP44512.1 - 5e-13 49.0 0.0 6.2e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDP44512.1 - 8.2e-07 28.9 0.0 1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain EF1G PF00647.14 EDP44513.1 - 4.1e-45 151.8 0.1 1.3e-44 150.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C_2 PF13410.1 EDP44513.1 - 3.8e-09 36.3 0.0 6.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDP44513.1 - 7.3e-09 35.4 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDP44513.1 - 5.3e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Flavodoxin_1 PF00258.20 EDP44514.1 - 9.2e-32 109.9 0.0 1.3e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EDP44514.1 - 5.2e-05 22.7 0.0 7.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_1 PF00667.15 EDP44515.1 - 2.5e-19 69.6 0.2 2.2e-15 56.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EDP44515.1 - 4.1e-12 46.6 0.0 5.1e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain COX6C PF02937.10 EDP44516.1 - 0.063 13.1 0.0 0.07 13.0 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Peptidase_M24 PF00557.19 EDP44517.1 - 1.9e-35 122.3 0.0 2.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pantoate_ligase PF02569.10 EDP44518.1 - 1.7e-79 266.4 0.0 2.5e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ras PF00071.17 EDP44519.1 - 3.8e-60 201.9 0.1 4.4e-60 201.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP44519.1 - 1.8e-18 67.1 0.0 2.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP44519.1 - 4.6e-12 45.5 0.0 5.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDP44519.1 - 5.2e-06 26.0 0.0 6.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDP44519.1 - 5.4e-06 25.7 0.0 6.5e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDP44519.1 - 8e-05 22.5 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Hpr_kinase_C PF07475.7 EDP44519.1 - 0.041 13.1 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RRM_1 PF00076.17 EDP44520.1 - 3.5e-13 48.9 0.0 9.2e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44520.1 - 9e-10 38.2 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44520.1 - 1.5e-06 28.0 0.1 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 EDP44521.1 - 1.5e-08 34.6 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDP44521.1 - 1.4e-07 31.4 0.0 2.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_N PF00176.18 EDP44522.1 - 1.6e-41 142.0 0.0 2.3e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EDP44522.1 - 3.5e-05 23.3 10.8 8.8e-05 22.0 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP44522.1 - 6.1e-05 22.7 14.1 6.1e-05 22.7 9.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP44522.1 - 8.7e-05 22.4 13.8 0.00027 20.8 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP44522.1 - 0.00017 21.1 15.3 0.00019 21.0 9.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EDP44522.1 - 0.00055 19.7 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EDP44522.1 - 0.0012 18.5 13.4 0.0029 17.2 9.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C_4 PF13871.1 EDP44522.1 - 0.0016 17.8 4.0 0.0026 17.2 0.4 2.4 2 0 0 2 2 2 1 Helicase_C-like Prok-RING_4 PF14447.1 EDP44522.1 - 0.0046 16.4 8.4 0.013 15.0 5.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 EDP44522.1 - 0.12 12.1 4.5 0.12 12.1 1.7 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 EDP44522.1 - 0.17 11.4 8.7 0.41 10.2 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EDP44522.1 - 0.22 11.3 6.2 0.69 9.7 4.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 EDP44522.1 - 0.57 9.9 2.7 1.6 8.4 1.8 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EDP44522.1 - 3.8 7.4 11.4 8.7 6.3 7.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING COX5A PF02284.11 EDP44523.1 - 3.8e-38 129.7 0.2 4.5e-38 129.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va KNOX2 PF03791.8 EDP44523.1 - 0.12 11.6 0.4 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 KNOX2 domain Oxidored-like PF09791.4 EDP44524.1 - 7.6e-17 60.4 2.6 1.4e-16 59.6 1.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ABC1 PF03109.11 EDP44525.1 - 3e-30 104.6 0.0 4.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 EDP44525.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TFIIA PF03153.8 EDP44525.1 - 6.9 6.4 6.4 9.7 5.9 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.14 EDP44526.1 - 2.3e-116 388.4 0.0 2.6e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDP44526.1 - 0.00054 18.6 0.0 0.0041 15.7 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Plus-3 PF03126.13 EDP44527.1 - 4.5e-16 58.8 0.0 1.1e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain PseudoU_synth_1 PF01416.15 EDP44528.1 - 1.4e-11 44.7 0.0 2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 tRNA pseudouridine synthase TPR_11 PF13414.1 EDP44529.1 - 1.6e-17 62.9 4.2 6.2e-15 54.6 2.3 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDP44529.1 - 1.9e-09 36.7 4.0 0.00037 20.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP44529.1 - 7.4e-08 31.6 2.6 0.00018 20.9 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44529.1 - 1.2e-07 31.7 5.7 0.076 13.6 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44529.1 - 2.3e-07 31.0 5.7 0.003 17.8 0.8 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44529.1 - 1.9e-06 28.3 5.4 0.0015 19.1 1.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44529.1 - 7.4e-06 25.8 4.2 6.9e-05 22.7 0.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDP44529.1 - 2.9e-05 24.1 1.0 0.035 14.2 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDP44529.1 - 0.0014 18.9 1.7 0.57 10.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44529.1 - 0.0029 17.6 1.3 0.094 12.9 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44529.1 - 0.0035 17.0 1.6 1.6 8.6 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44529.1 - 0.0062 16.2 1.4 0.51 10.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDP44529.1 - 0.0071 15.4 3.0 0.012 14.6 2.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44529.1 - 0.029 14.2 5.2 0.61 9.9 2.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDP44529.1 - 0.07 13.0 3.6 3.2 7.6 0.6 2.6 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EDP44529.1 - 3.4 7.7 5.5 33 4.5 1.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.26 EDP44530.1 - 1.7e-24 85.3 4.1 9.8e-24 82.8 0.5 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EDP44530.1 - 8.4e-19 66.9 6.3 2.3e-12 46.3 0.5 3.4 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 EDP44530.1 - 2.8e-16 58.3 2.2 1.4e-06 27.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44530.1 - 9.7e-15 53.2 7.2 0.00079 19.1 0.0 5.1 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44530.1 - 1.2e-07 32.2 14.3 0.0056 17.3 0.1 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44530.1 - 1.5e-07 31.2 11.5 5.1e-06 26.3 0.5 4.2 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44530.1 - 1.6e-05 25.1 17.7 0.23 12.1 0.4 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44530.1 - 1.7e-05 25.0 15.1 0.0041 17.4 2.8 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44530.1 - 2.2e-05 24.2 3.0 0.72 10.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDP44530.1 - 3e-05 23.7 11.4 0.19 11.5 0.6 3.6 2 1 2 4 4 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDP44530.1 - 3.2e-05 23.0 0.2 0.11 11.7 0.1 2.8 2 0 0 2 2 2 2 SHNi-TPR TPR_8 PF13181.1 EDP44530.1 - 0.00011 21.7 1.7 1.3 8.9 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44530.1 - 0.0003 20.3 8.6 0.64 9.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDP44530.1 - 0.025 14.7 7.4 0.48 10.5 0.3 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EDP44530.1 - 0.63 9.9 6.1 4.8 7.1 0.5 3.2 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EDP44530.1 - 1.7 8.7 14.5 9.3 6.3 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDP44530.1 - 4.9 7.8 7.0 8.4 7.1 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat WD40 PF00400.27 EDP44531.1 - 8e-53 174.5 16.8 5e-11 42.0 0.1 9.1 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 EDP44531.1 - 1.1e-09 37.8 0.3 3.6e-09 36.2 0.2 2.0 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EDP44531.1 - 2.9e-06 25.7 6.6 0.051 11.7 0.0 4.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDP44531.1 - 0.0038 16.7 5.7 0.18 11.2 1.6 3.7 1 1 2 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 EDP44531.1 - 0.0039 17.4 5.3 6.6 7.1 0.2 5.0 5 0 0 5 5 5 1 PQQ-like domain F-box PF00646.28 EDP44531.1 - 0.0048 16.5 0.1 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EDP44531.1 - 0.058 13.1 0.0 0.96 9.2 0.0 2.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Kelch_6 PF13964.1 EDP44531.1 - 0.091 12.9 1.2 36 4.7 0.0 4.1 5 0 0 5 5 5 0 Kelch motif Nucleoporin_N PF08801.6 EDP44531.1 - 0.3 9.7 0.3 15 4.1 0.0 3.1 2 2 1 3 3 3 0 Nup133 N terminal like Ctr PF04145.10 EDP44532.1 - 6.6e-36 123.5 1.1 8.8e-36 123.1 0.8 1.2 1 0 0 1 1 1 1 Ctr copper transporter family PIG-H PF10181.4 EDP44533.1 - 5.9e-08 32.2 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Abhydrolase_5 PF12695.2 EDP44533.1 - 0.0045 16.7 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EDP44534.1 - 1.6e-10 40.4 1.0 0.99 9.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Zw10 PF06248.8 EDP44535.1 - 4.2e-08 31.8 0.6 0.00048 18.4 0.0 2.8 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EDP44535.1 - 0.00016 20.9 0.1 0.00029 20.1 0.0 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal OKR_DC_1_N PF03709.10 EDP44535.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain NYD-SP12_N PF15015.1 EDP44535.1 - 0.16 10.1 0.1 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal LSM PF01423.17 EDP44536.1 - 1.9e-17 62.5 0.1 2.5e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain COPIIcoated_ERV PF07970.7 EDP44537.1 - 1.1e-35 123.2 0.3 2.6e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDP44537.1 - 4.5e-09 36.1 0.1 1.5e-08 34.4 0.1 1.9 1 1 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) YbgT_YccB PF08173.6 EDP44537.1 - 0.053 13.3 0.2 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Membrane bound YbgT-like protein DUF4110 PF13422.1 EDP44538.1 - 1e-13 50.9 0.0 3.2e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EDP44538.1 - 1.2e-10 41.2 0.3 0.00019 21.4 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EDP44538.1 - 1e-06 28.3 9.6 0.026 14.3 0.0 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDP44538.1 - 5.6e-06 26.3 0.4 0.0057 16.7 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 EDP44538.1 - 0.001 18.7 0.0 0.24 11.2 0.1 3.4 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 EDP44538.1 - 0.016 15.1 4.8 0.82 9.6 0.1 3.8 4 1 0 4 4 4 0 Kelch motif Miff PF05644.6 EDP44538.1 - 0.018 14.6 1.4 0.088 12.4 1.0 1.9 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF2722 PF10846.3 EDP44538.1 - 0.025 13.6 0.6 0.036 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Kelch_1 PF01344.20 EDP44538.1 - 0.054 13.0 0.8 0.24 10.9 0.2 2.4 3 0 0 3 3 3 0 Kelch motif Nop14 PF04147.7 EDP44538.1 - 0.13 10.1 9.0 0.14 10.0 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 EDP44538.1 - 0.5 10.1 8.1 4.8 6.9 4.8 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.7 EDP44538.1 - 0.54 9.4 6.6 1 8.5 4.6 1.4 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EDP44538.1 - 1.6 7.1 12.5 2.2 6.6 8.7 1.1 1 0 0 1 1 1 0 Daxx Family SpoIIE PF07228.7 EDP44539.1 - 1.4e-12 47.7 0.0 1.2e-11 44.6 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EDP44539.1 - 1.2e-06 28.0 0.0 3.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C tRNA_anti-codon PF01336.20 EDP44540.1 - 0.015 15.1 0.1 0.065 13.0 0.1 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Nup96 PF12110.3 EDP44541.1 - 9.8e-81 271.0 3.0 1.3e-80 270.6 2.1 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EDP44541.1 - 4.8e-39 133.3 0.0 1.1e-38 132.2 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EDP44541.1 - 1.6e-15 57.3 261.3 3.6e-08 33.6 32.6 7.7 3 1 4 7 7 7 4 Nucleoporin FG repeat region DUF2457 PF10446.4 EDP44541.1 - 0.87 8.2 9.1 1.7 7.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ketoacyl-synt PF00109.21 EDP44542.1 - 2.4e-63 214.0 0.1 4.5e-63 213.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EDP44542.1 - 8.2e-49 165.7 0.1 2.3e-48 164.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.16 EDP44542.1 - 5.1e-45 154.1 0.2 1e-44 153.1 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EDP44542.1 - 1e-35 123.0 0.7 1e-33 116.5 0.0 3.0 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.17 EDP44542.1 - 6.3e-33 113.1 0.0 1.4e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDP44542.1 - 1.2e-30 106.6 0.5 6.2e-28 97.7 0.0 3.0 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EDP44542.1 - 8.8e-26 90.7 0.0 1.7e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EDP44542.1 - 1e-15 57.8 0.0 3.8e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EDP44542.1 - 5.2e-12 45.4 0.0 2.5e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EDP44542.1 - 1.4e-09 38.2 1.6 2.8e-05 24.2 0.4 4.2 3 1 0 3 3 3 2 NADH(P)-binding 3Beta_HSD PF01073.14 EDP44542.1 - 3.8e-05 22.5 0.3 0.0017 17.0 0.1 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDP44542.1 - 0.00014 20.9 0.1 0.00075 18.4 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein PP-binding PF00550.20 EDP44542.1 - 0.0012 19.1 0.5 0.0035 17.5 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EDP44542.1 - 0.0016 19.3 0.2 0.015 16.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EDP44542.1 - 0.0021 17.9 0.1 0.0083 16.0 0.1 2.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_N PF08240.7 EDP44542.1 - 0.0067 16.1 0.3 0.024 14.4 0.1 2.0 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 EDP44542.1 - 0.034 13.3 0.1 0.1 11.8 0.1 1.8 1 0 0 1 1 1 0 NmrA-like family Nramp PF01566.13 EDP44544.1 - 3.3e-88 295.9 15.5 1.3e-50 172.2 1.4 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein MRP-L47 PF06984.8 EDP44545.1 - 9.3e-19 67.1 0.3 1.5e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 EDP44545.1 - 0.00082 19.0 0.1 0.0065 16.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3703 PF12487.3 EDP44545.1 - 0.035 13.7 1.6 0.91 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) Chorein_N PF12624.2 EDP44546.1 - 2.9e-37 126.7 0.4 9.2e-37 125.1 0.2 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 EDP44547.1 - 3.7e-56 190.3 0.0 3.9e-54 183.7 0.0 3.4 5 0 0 5 5 5 1 Protein of unknown function (DUF1162) DUF756 PF05506.7 EDP44547.1 - 0.0023 18.3 0.0 0.57 10.6 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF756) LBP_BPI_CETP_C PF02886.12 EDP44547.1 - 0.032 13.4 0.5 0.075 12.2 0.4 1.5 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Glycolytic PF00274.14 EDP44547.1 - 0.33 9.2 0.5 5 5.4 0.1 2.3 2 0 0 2 2 2 0 Fructose-bisphosphate aldolase class-I ATG_C PF09333.6 EDP44548.1 - 5.9e-06 26.3 0.0 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain CBFB_NFYA PF02045.10 EDP44549.1 - 1.8e-29 102.0 3.1 3.8e-29 101.0 2.1 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B MscS_TM PF12794.2 EDP44549.1 - 0.88 8.1 8.1 2.2 6.8 1.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Dynein_heavy PF03028.10 EDP44550.1 - 1.2e-95 321.1 0.0 2.5e-95 320.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 EDP44550.1 - 1.5e-40 138.4 0.0 3.8e-40 137.1 0.0 1.6 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EDP44550.1 - 3.1e-38 131.4 1.7 5.2e-38 130.6 1.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor LUC7 PF03194.10 EDP44550.1 - 0.55 9.7 17.5 0.45 10.0 5.4 3.3 3 0 0 3 3 3 0 LUC7 N_terminus THOC7 PF05615.8 EDP44550.1 - 2.7 8.2 19.2 0.16 12.2 0.6 4.3 3 2 0 3 3 3 0 Tho complex subunit 7 DUF724 PF05266.9 EDP44550.1 - 4 7.0 21.4 2.7 7.5 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF724) LRR_9 PF14580.1 EDP44551.1 - 1.6e-46 158.0 0.7 1.8e-46 157.9 0.1 1.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EDP44551.1 - 1e-13 50.5 6.8 1.1e-07 31.3 0.5 3.3 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP44551.1 - 2e-10 40.2 11.1 2.5e-07 30.3 1.2 3.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EDP44551.1 - 0.00037 20.2 1.3 27 5.2 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 EDP44551.1 - 0.0042 16.9 4.0 19 5.7 0.0 5.2 5 1 0 5 5 5 1 Leucine Rich Repeat HTH_38 PF13936.1 EDP44551.1 - 0.24 10.9 2.3 0.25 10.8 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_7 PF13504.1 EDP44551.1 - 0.25 11.6 6.9 49 4.7 0.0 5.1 4 1 1 5 5 5 0 Leucine rich repeat Septin PF00735.13 EDP44552.1 - 2.5e-49 167.8 0.2 2.5e-49 167.8 0.2 1.6 2 0 0 2 2 2 1 Septin Strep_SA_rep PF06696.6 EDP44552.1 - 0.0016 18.1 5.3 0.0074 16.0 0.0 2.8 2 0 0 2 2 2 1 Streptococcal surface antigen repeat DUF1796 PF08795.5 EDP44552.1 - 0.13 11.8 2.6 0.22 11.1 1.8 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) UPF0449 PF15136.1 EDP44552.1 - 0.17 12.0 4.0 0.6 10.3 2.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_GPO PF05929.6 EDP44552.1 - 0.25 10.5 5.6 0.38 9.9 3.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 EDP44552.1 - 0.4 9.8 9.4 0.37 9.9 5.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit KfrA_N PF11740.3 EDP44552.1 - 2.1 8.7 13.4 6.1 7.3 9.3 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term TMPIT PF07851.8 EDP44552.1 - 2.2 7.2 5.6 4.4 6.2 2.4 2.0 2 0 0 2 2 2 0 TMPIT-like protein DHC_N1 PF08385.7 EDP44553.1 - 6.1e-128 427.7 0.0 9.9e-128 427.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EDP44553.1 - 2.3e-99 332.6 0.0 5.6e-99 331.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EDP44553.1 - 3.1e-68 229.7 0.0 5.9e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EDP44553.1 - 9.6e-26 90.1 0.0 1.7e-10 40.7 0.0 5.4 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EDP44553.1 - 2.2e-19 69.5 0.0 2.3e-18 66.2 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EDP44553.1 - 7.7e-17 61.6 0.0 8.9e-06 25.8 0.0 6.2 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 EDP44553.1 - 9.1e-12 45.3 0.0 0.004 17.3 0.0 5.2 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.2 EDP44553.1 - 3.3e-07 29.5 0.0 7.7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_18 PF13238.1 EDP44553.1 - 7.4e-07 29.5 0.0 1 9.6 0.0 4.8 4 1 0 4 4 4 1 AAA domain AAA_17 PF13207.1 EDP44553.1 - 9.7e-07 29.6 0.0 0.6 10.9 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 EDP44553.1 - 1.2e-06 28.4 2.0 0.12 12.2 0.0 5.7 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 EDP44553.1 - 1.3e-06 28.0 17.3 0.083 12.6 0.0 7.2 6 0 0 6 6 5 2 Part of AAA domain Sigma54_activ_2 PF14532.1 EDP44553.1 - 3.6e-05 23.8 0.2 7.4 6.6 0.0 5.5 5 0 0 5 5 5 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDP44553.1 - 5.2e-05 22.4 2.6 1 8.4 0.0 4.3 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDP44553.1 - 0.0006 19.5 1.1 3.2 7.3 0.0 4.9 5 0 0 5 5 5 1 NACHT domain T2SE PF00437.15 EDP44553.1 - 0.00067 18.6 0.0 0.24 10.2 0.0 3.7 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_14 PF13173.1 EDP44553.1 - 0.00089 19.1 0.0 0.7 9.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EDP44553.1 - 0.0013 17.8 0.0 0.086 11.9 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin UPF0079 PF02367.12 EDP44553.1 - 0.022 14.3 1.5 5.4 6.6 0.0 4.2 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EDP44553.1 - 0.025 14.7 0.0 50 4.1 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 EDP44553.1 - 0.037 14.3 0.0 35 4.6 0.0 4.2 4 0 0 4 4 4 0 ABC transporter Arch_ATPase PF01637.13 EDP44553.1 - 0.051 13.2 0.0 0.3 10.7 0.0 2.3 3 0 0 3 3 2 0 Archaeal ATPase AAA_11 PF13086.1 EDP44553.1 - 0.11 12.0 0.0 3.6 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDP44553.1 - 0.12 11.5 0.5 85 2.2 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein DEAD PF00270.24 EDP44553.1 - 0.12 11.8 0.0 12 5.2 0.0 3.5 5 0 0 5 5 3 0 DEAD/DEAH box helicase AAA_24 PF13479.1 EDP44553.1 - 0.15 11.6 0.1 18 4.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EDP44553.1 - 0.16 11.1 0.0 19 4.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 EDP44553.1 - 0.3 10.5 0.2 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 EDP44553.1 - 0.38 9.6 0.0 8.9 5.1 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF1759 PF03564.10 EDP44553.1 - 0.39 10.5 0.0 1e+02 2.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Guanylate_kin PF00625.16 EDP44553.1 - 0.9 8.9 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase LEF-9 PF05094.7 EDP44553.1 - 1.7 6.9 0.0 2.9 6.1 0.0 1.2 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) Baculo_PEP_C PF04513.7 EDP44553.1 - 1.9 8.2 3.7 40 4.0 0.0 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Abhydrolase_6 PF12697.2 EDP44554.1 - 2.1e-08 34.3 1.0 2.1e-08 34.3 0.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44554.1 - 0.003 17.1 0.0 0.072 12.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 EDP44554.1 - 0.028 13.7 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) BATS PF06968.8 EDP44555.1 - 2e-26 91.6 0.0 5.1e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EDP44555.1 - 1e-15 58.3 0.1 2e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily NUDIX PF00293.23 EDP44556.1 - 2.4e-13 49.8 0.1 4.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PTH2 PF01981.11 EDP44557.1 - 4.1e-45 152.1 0.0 5.5e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BNR_2 PF13088.1 EDP44557.1 - 0.074 12.3 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain gag-asp_proteas PF13975.1 EDP44557.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PhzC-PhzF PF02567.11 EDP44557.1 - 0.12 11.5 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Phenazine biosynthesis-like protein ubiquitin PF00240.18 EDP44558.1 - 4.3e-70 231.0 6.6 1.3e-34 117.3 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EDP44558.1 - 3.8e-40 135.4 6.4 1.4e-19 69.5 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDP44558.1 - 2.7e-13 49.9 1.6 4.6e-05 23.5 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDP44558.1 - 9.5e-11 41.6 0.1 0.0004 20.0 0.0 2.0 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDP44558.1 - 2.1e-07 30.8 0.3 0.031 14.1 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDP44558.1 - 8.5e-07 29.0 0.1 0.043 14.0 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDP44558.1 - 4.7e-05 23.3 0.0 0.54 10.3 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EDP44558.1 - 0.00054 19.6 0.5 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain TUG-UBL1 PF11470.3 EDP44558.1 - 0.0016 18.3 0.4 1.8 8.5 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF3221 PF11518.3 EDP44558.1 - 0.01 15.5 0.1 4.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) Plexin_cytopl PF08337.7 EDP44558.1 - 0.017 13.4 4.1 1.2 7.3 0.2 3.3 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EDP44558.1 - 0.071 13.0 10.5 1.5 8.8 1.2 2.3 2 0 0 2 2 2 0 Tash protein PEST motif USP7_C2 PF14533.1 EDP44558.1 - 0.073 12.4 0.3 9.8 5.5 0.0 2.1 1 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal GABP-alpha PF11620.3 EDP44558.1 - 0.11 12.5 0.7 13 5.8 0.1 2.1 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3861 PF12977.2 EDP44558.1 - 0.11 12.6 1.0 22 5.2 0.0 2.7 1 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2207 PF09972.4 EDP44558.1 - 0.13 10.8 3.3 3.9 5.9 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FERM_N PF09379.5 EDP44558.1 - 0.34 10.9 3.5 28 4.8 0.2 3.4 2 2 0 2 2 2 0 FERM N-terminal domain CDC48_2 PF02933.12 EDP44558.1 - 0.51 10.0 2.8 12 5.5 0.1 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 ATP-synt_F PF01990.12 EDP44559.1 - 4.2e-29 100.7 0.2 4.8e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 EDP44559.1 - 0.06 12.6 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Hist_deacetyl PF00850.14 EDP44560.1 - 4.5e-64 216.6 0.7 5.7e-64 216.3 0.1 1.4 2 0 0 2 2 2 1 Histone deacetylase domain GYF PF02213.11 EDP44561.1 - 8.5e-14 50.8 0.3 1.8e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 GYF domain RRP7 PF12923.2 EDP44561.1 - 0.0047 16.9 2.5 0.66 9.9 0.0 2.8 3 0 0 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) DUF4339 PF14237.1 EDP44561.1 - 0.078 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) 4HBT_3 PF13622.1 EDP44563.1 - 2.9e-17 63.2 0.0 4.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EDP44563.1 - 1.1e-14 54.2 1.3 7.8e-11 41.7 0.1 3.6 3 1 1 4 4 4 2 Acyl-CoA thioesterase Sec1 PF00995.18 EDP44564.1 - 1.6e-140 469.4 0.0 1.8e-140 469.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family LMWPc PF01451.16 EDP44565.1 - 4.5e-28 98.2 0.1 8.9e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CTDII PF01556.13 EDP44565.1 - 2.3e-26 91.5 0.1 6.1e-21 74.1 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EDP44565.1 - 3.9e-23 80.9 1.5 6.6e-23 80.2 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDP44565.1 - 3.6e-11 42.9 17.4 5.9e-11 42.2 11.4 1.9 2 0 0 2 2 2 1 DnaJ central domain Nol1_Nop2_Fmu PF01189.12 EDP44566.1 - 7.8e-30 104.2 0.0 1.9e-17 63.5 0.0 3.7 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EDP44566.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_carr PF00153.22 EDP44567.1 - 1.9e-19 69.1 0.0 3.6e-07 29.7 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Glyco_transf_4 PF13439.1 EDP44568.1 - 1.1e-10 41.5 0.6 2.1e-08 34.0 0.4 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDP44568.1 - 1.3e-09 38.4 10.5 3.3e-09 37.0 4.6 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EDP44568.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cep57_MT_bd PF06657.8 EDP44569.1 - 1.5e-08 34.4 2.7 1.5e-08 34.4 1.9 4.1 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 DUF1978 PF09321.5 EDP44569.1 - 0.0012 18.3 2.0 0.0012 18.3 1.4 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1978) NPV_P10 PF05531.7 EDP44569.1 - 0.017 15.3 0.3 0.049 13.8 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.4 EDP44569.1 - 0.53 10.5 3.5 30 4.8 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.3 EDP44569.1 - 3.7 7.5 11.9 0.53 10.3 4.3 2.4 2 0 0 2 2 2 0 YlqD protein DUF4239 PF14023.1 EDP44569.1 - 7 5.9 9.8 0.48 9.7 2.8 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) SUI1 PF01253.17 EDP44570.1 - 7e-31 105.8 1.6 1.6e-30 104.7 0.3 1.8 1 1 1 2 2 2 1 Translation initiation factor SUI1 Fcf1 PF04900.7 EDP44571.1 - 3.7e-40 136.0 2.1 4.2e-40 135.9 0.5 1.7 2 0 0 2 2 2 1 Fcf1 UreD PF01774.12 EDP44572.1 - 1.5e-50 171.5 0.0 2e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein SEEK1 PF15357.1 EDP44572.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Pkinase PF00069.20 EDP44573.1 - 3.9e-62 209.7 0.0 7.9e-62 208.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44573.1 - 4.5e-26 91.4 0.0 5.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44573.1 - 1.1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP44573.1 - 0.00099 18.9 0.2 0.0072 16.0 0.0 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDP44573.1 - 0.008 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EDP44573.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.16 EDP44574.1 - 2.3e-65 219.0 0.0 2.8e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDP44574.1 - 4.8e-09 35.3 0.1 9.7e-06 24.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EDP44574.1 - 7.6e-09 35.0 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EDP44574.1 - 5.9e-08 33.2 0.0 9.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP44574.1 - 1.4e-06 28.2 0.0 4.5e-06 26.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EDP44574.1 - 2.2e-06 27.1 0.0 3.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EDP44574.1 - 2.8e-05 23.3 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDP44574.1 - 0.014 14.8 0.0 0.32 10.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EDP44574.1 - 0.022 14.2 0.0 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EDP44576.1 - 1.3e-56 186.5 24.6 4.7e-09 35.7 0.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EDP44576.1 - 3.4e-10 39.4 0.2 8.5e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EDP44576.1 - 2.4e-09 35.9 16.9 0.074 11.1 0.0 6.1 2 2 3 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EDP44576.1 - 4.3e-08 32.6 0.4 1.2e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 EDP44577.1 - 3.1e-53 180.9 0.0 5.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sec7_N PF12783.2 EDP44579.1 - 8.8e-25 87.0 0.1 8.8e-25 87.0 0.1 2.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDP44579.1 - 0.00012 21.4 0.0 0.00084 18.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Reo_sigmaC PF04582.7 EDP44580.1 - 0.00019 20.7 10.5 0.00093 18.4 2.7 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 EDP44580.1 - 0.012 15.2 30.7 0.54 9.8 11.9 2.6 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 EDP44580.1 - 0.016 15.3 3.4 0.016 15.3 2.3 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RPW8 PF05659.6 EDP44580.1 - 0.018 14.5 0.4 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TBPIP PF07106.8 EDP44580.1 - 0.039 13.5 15.1 0.073 12.6 1.3 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EDP44580.1 - 0.07 11.4 20.5 0.05 11.9 2.1 2.4 1 1 1 2 2 2 0 Transmembrane protein Filament PF00038.16 EDP44580.1 - 0.11 12.0 25.9 1 8.7 7.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 EDP44580.1 - 0.17 12.2 15.3 2.1 8.7 4.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF972) ADIP PF11559.3 EDP44580.1 - 0.53 10.1 30.3 0.78 9.6 10.9 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.6 EDP44580.1 - 0.58 8.5 17.3 1 7.7 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.7 EDP44580.1 - 0.71 9.6 8.8 2.4 7.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EDP44580.1 - 0.85 8.2 17.0 0.63 8.6 2.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2353 PF09789.4 EDP44580.1 - 1.3 8.2 17.9 5.3 6.2 0.5 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF4200 PF13863.1 EDP44580.1 - 1.8 8.5 19.0 2.3 8.2 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 EDP44580.1 - 1.9 7.6 20.3 3 6.9 2.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 EDP44580.1 - 2.6 8.2 8.0 6.5 6.9 0.8 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 EDP44580.1 - 4.9 7.0 26.1 33 4.3 9.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EDP44580.1 - 5.9 7.2 13.1 6 7.1 0.0 4.5 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 EDP44580.1 - 7.8 5.4 23.2 2.1 7.3 2.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EDP44580.1 - 8.6 5.9 22.3 8.4 6.0 3.0 2.9 1 1 2 3 3 3 0 Mnd1 family P5CR_dimer PF14748.1 EDP44581.1 - 3.5e-37 126.6 4.4 3.5e-37 126.6 3.0 2.3 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDP44581.1 - 1.9e-11 44.1 2.0 3.5e-10 40.1 0.4 2.7 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EDP44581.1 - 0.012 14.4 0.1 0.054 12.3 0.0 1.8 2 0 0 2 2 2 0 Prephenate dehydrogenase IlvN PF07991.7 EDP44581.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain eIF-5a PF01287.15 EDP44581.1 - 0.058 13.3 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold AAA PF00004.24 EDP44582.1 - 2.1e-45 154.1 0.1 1.1e-44 151.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP44582.1 - 5.8e-09 35.7 0.1 2.4e-08 33.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDP44582.1 - 1.3e-07 31.6 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDP44582.1 - 9.4e-07 28.9 0.0 3.7e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDP44582.1 - 1.2e-06 28.7 0.3 0.00043 20.4 0.2 3.0 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EDP44582.1 - 3.4e-06 26.1 0.3 1.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EDP44582.1 - 0.0002 20.4 0.0 0.00041 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDP44582.1 - 0.00038 20.4 0.1 0.00082 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EDP44582.1 - 0.0004 20.0 0.0 0.0012 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP44582.1 - 0.00044 19.9 0.1 0.0013 18.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDP44582.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDP44582.1 - 0.001 18.8 0.1 0.0042 16.7 0.0 2.2 3 0 0 3 3 1 1 NTPase NACHT PF05729.7 EDP44582.1 - 0.0011 18.6 0.1 0.033 13.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 EDP44582.1 - 0.0015 18.0 0.8 0.022 14.1 0.0 2.5 3 0 0 3 3 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EDP44582.1 - 0.0018 18.4 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EDP44582.1 - 0.0018 19.0 0.0 0.0046 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP44582.1 - 0.0031 17.8 0.0 0.0098 16.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDP44582.1 - 0.0033 17.3 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDP44582.1 - 0.0039 16.6 1.0 0.05 13.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDP44582.1 - 0.0052 15.9 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDP44582.1 - 0.0053 16.4 0.1 0.054 13.1 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 EDP44582.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDP44582.1 - 0.006 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 EDP44582.1 - 0.0077 15.8 0.0 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDP44582.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EDP44582.1 - 0.011 16.0 1.3 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDP44582.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EDP44582.1 - 0.012 14.2 0.1 0.032 12.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Bac_DnaA PF00308.13 EDP44582.1 - 0.026 14.1 0.0 0.08 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein RIG-I_C-RD PF11648.3 EDP44582.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of RIG-I Sigma54_activ_2 PF14532.1 EDP44582.1 - 0.033 14.2 0.3 1.1 9.2 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EDP44582.1 - 0.055 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 EDP44582.1 - 0.069 11.9 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.21 EDP44582.1 - 0.07 12.5 0.2 1.2 8.5 0.0 2.7 2 2 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 EDP44582.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EDP44582.1 - 0.24 10.4 1.4 0.73 8.8 0.0 2.4 3 1 0 3 3 3 0 KaiC UL97 PF06734.7 EDP44583.1 - 0.11 11.8 0.2 0.18 11.1 0.1 1.4 1 1 0 1 1 1 0 UL97 QH-AmDH_gamma PF08992.6 EDP44583.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit SET PF00856.23 EDP44584.1 - 1.9e-09 38.0 0.4 1.9e-09 38.0 0.3 3.0 2 2 0 2 2 2 1 SET domain Paramyxo_ncap PF00973.14 EDP44584.1 - 2.3 6.8 4.0 3.7 6.1 2.8 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Phosphoesterase PF04185.9 EDP44585.1 - 2e-77 260.9 4.1 2.6e-77 260.5 2.9 1.1 1 0 0 1 1 1 1 Phosphoesterase family SH2_2 PF14633.1 EDP44586.1 - 2.6e-70 235.9 0.0 5.7e-70 234.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EDP44586.1 - 1.6e-23 82.9 0.0 1.6e-23 82.9 0.0 3.3 4 0 0 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 EDP44586.1 - 1.9e-23 82.6 0.0 4.9e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EDP44586.1 - 1.8e-19 69.7 0.0 4.1e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EDP44586.1 - 2.4e-16 59.6 23.8 2.4e-16 59.6 16.5 4.0 3 1 0 3 3 3 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EDP44586.1 - 2.4e-07 30.7 0.0 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EDP44586.1 - 0.0009 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EDP44586.1 - 0.0028 17.7 0.1 0.0089 16.0 0.1 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Tex_N PF09371.5 EDP44586.1 - 0.0037 16.6 0.0 0.0096 15.2 0.0 1.7 1 0 0 1 1 1 1 Tex-like protein N-terminal domain CTD PF12815.2 EDP44586.1 - 0.013 15.9 15.5 0.029 14.7 10.7 1.6 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 SOG2 PF10428.4 EDP44587.1 - 8.8e-44 149.8 14.0 8.8e-44 149.8 9.7 2.1 2 0 0 2 2 2 1 RAM signalling pathway protein Dynamin_N PF00350.18 EDP44587.1 - 0.12 12.2 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Dynamin family RRM_1 PF00076.17 EDP44588.1 - 8.5e-10 38.1 0.1 2.9e-06 26.8 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44588.1 - 7.4e-09 35.4 0.0 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EDP44588.1 - 0.0054 16.8 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RRM_5 PF13893.1 EDP44588.1 - 0.0072 16.1 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 EDP44588.1 - 0.017 15.4 0.3 0.044 14.1 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP44588.1 - 0.055 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EDP44588.1 - 0.18 12.0 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Glyco_hydro_63 PF03200.11 EDP44589.1 - 6.5e-206 685.7 0.0 7.9e-205 682.1 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EDP44589.1 - 6.8e-07 28.2 0.1 4.2e-06 25.6 0.0 1.8 1 1 1 2 2 2 1 Trehalase SMI1_KNR4 PF09346.5 EDP44590.1 - 1.3e-24 86.6 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) MFS_1_like PF12832.2 EDP44591.1 - 3.3e-20 71.6 1.0 3.3e-20 71.6 0.7 2.4 2 0 0 2 2 2 1 MFS_1 like family Phosducin PF02114.11 EDP44592.1 - 0.00019 20.2 0.0 0.0002 20.2 0.0 1.1 1 0 0 1 1 1 1 Phosducin GST_N_2 PF13409.1 EDP44593.1 - 1.4e-07 31.3 0.0 3.6e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDP44593.1 - 1.5e-07 31.5 0.0 3.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDP44593.1 - 6.2e-05 23.0 0.0 0.00018 21.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDP44593.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDP44593.1 - 0.0044 17.4 0.0 0.007 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDP44593.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Herpes_gE PF02480.11 EDP44595.1 - 0.00024 19.5 0.0 0.00044 18.6 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 EDP44595.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Syndecan PF01034.15 EDP44595.1 - 0.21 11.2 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain zf-C2H2 PF00096.21 EDP44596.1 - 6.7e-11 41.8 16.1 2.6e-05 24.3 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP44596.1 - 8.5e-08 32.0 14.2 0.0001 22.3 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDP44596.1 - 2.3e-06 27.5 21.1 4.8e-05 23.4 0.9 4.3 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDP44596.1 - 7.1e-05 22.8 1.9 7.1e-05 22.8 1.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDP44596.1 - 0.0099 16.0 1.5 0.038 14.1 1.0 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDP44596.1 - 0.05 13.5 2.2 0.05 13.5 1.5 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EDP44596.1 - 4.3 7.1 11.7 0.044 13.5 1.6 2.2 2 0 0 2 2 2 0 BED zinc finger NAD_kinase PF01513.16 EDP44597.1 - 5.2e-64 215.7 0.0 1e-63 214.7 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase NOA36 PF06524.7 EDP44597.1 - 6.8 5.8 10.0 9.9 5.3 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein TPPK_C PF12555.3 EDP44598.1 - 9.5 6.0 10.4 0.06 13.0 1.0 2.1 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal zf-RING_2 PF13639.1 EDP44599.1 - 2e-14 53.1 7.2 3.2e-14 52.4 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDP44599.1 - 4e-12 46.0 4.3 7.5e-12 45.1 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDP44599.1 - 5e-07 29.2 4.7 8.5e-07 28.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP44599.1 - 7.3e-07 29.1 3.8 1.5e-06 28.1 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44599.1 - 1.7e-06 27.6 4.9 2.7e-06 26.9 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDP44599.1 - 4.2e-06 26.3 6.8 1.2e-05 24.8 4.7 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDP44599.1 - 0.00041 20.0 3.8 0.00097 18.8 2.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDP44599.1 - 0.00087 19.0 6.3 0.0033 17.2 4.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EDP44599.1 - 0.0069 16.2 0.9 0.017 15.0 0.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EDP44599.1 - 0.08 12.9 4.3 0.2 11.6 3.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EDP44599.1 - 0.12 12.0 5.7 1 8.9 4.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EDP44599.1 - 0.31 11.1 3.8 0.71 9.9 2.7 1.6 1 1 0 1 1 1 0 RING-variant domain Ribosomal_L6 PF00347.18 EDP44600.1 - 3.9e-19 68.9 0.1 4.8e-12 46.2 0.0 3.3 4 1 0 4 4 4 2 Ribosomal protein L6 Ribosomal_L34e PF01199.13 EDP44601.1 - 5.4e-34 116.2 6.8 5.9e-34 116.1 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 EDP44601.1 - 0.0063 16.1 0.5 0.0096 15.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c7 FhuF_C PF11575.3 EDP44601.1 - 0.024 14.2 3.7 1.7 8.3 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Cytochrom_c3_2 PF14537.1 EDP44601.1 - 0.038 14.3 0.3 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c3 DUF4568 PF15132.1 EDP44601.1 - 0.074 12.2 0.5 0.084 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) zf-MYND PF01753.13 EDP44601.1 - 9.9 6.1 7.0 72 3.3 4.8 2.0 1 1 0 1 1 1 0 MYND finger Fungal_trans PF04082.13 EDP44602.1 - 9.4e-16 57.4 1.5 9.4e-16 57.4 1.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDP44602.1 - 3.3e-07 30.0 8.5 7.4e-07 28.9 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.11 EDP44603.1 - 5e-45 153.5 0.0 5.6e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDP44603.1 - 1.8e-10 40.7 0.3 2.4e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP44603.1 - 7.6e-09 35.7 0.5 9.5e-09 35.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDP44603.1 - 0.0011 18.5 0.1 0.0019 17.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EDP44603.1 - 0.0052 16.2 0.1 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.4 EDP44603.1 - 0.038 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Myosin_head PF00063.16 EDP44604.1 - 2.5e-203 676.9 0.0 4.1e-203 676.2 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EDP44604.1 - 2e-38 131.6 0.0 3.3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 EDP44604.1 - 2.1e-12 46.3 1.2 6.7e-12 44.7 0.2 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 EDP44604.1 - 2.3e-12 46.0 0.3 6.9e-12 44.5 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EDP44604.1 - 6.4e-07 28.7 0.1 2.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Hpr_kinase_C PF07475.7 EDP44604.1 - 0.0038 16.5 0.2 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 EDP44604.1 - 0.0039 17.3 0.1 0.015 15.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain SH3_3 PF08239.6 EDP44604.1 - 0.0039 17.3 0.5 0.011 15.9 0.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Zeta_toxin PF06414.7 EDP44604.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EDP44604.1 - 0.058 14.2 0.0 0.2 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDP44604.1 - 0.069 12.7 0.4 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDP44604.1 - 0.074 12.7 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EDP44604.1 - 0.15 12.3 0.1 0.46 10.7 0.1 1.7 1 0 0 1 1 1 0 ABC transporter IQ PF00612.22 EDP44604.1 - 4.9 7.0 15.2 1.6 8.6 3.0 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif zf-DHHC PF01529.15 EDP44605.1 - 7.2e-32 110.1 16.1 7.2e-32 110.1 11.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pex19 PF04614.7 EDP44606.1 - 6.2e-51 173.4 19.1 7.4e-51 173.1 12.6 1.6 1 1 0 1 1 1 1 Pex19 protein family Apolipoprotein PF01442.13 EDP44606.1 - 0.045 13.2 1.3 0.26 10.7 0.0 2.6 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Bromo_TP PF07524.8 EDP44606.1 - 0.13 12.0 0.0 0.44 10.3 0.0 1.9 1 0 0 1 1 1 0 Bromodomain associated Rubis-subs-bind PF09273.6 EDP44607.1 - 0.00013 21.8 0.1 0.0009 19.1 0.0 2.1 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Lyase_1 PF00206.15 EDP44607.1 - 0.0092 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lyase TRAM_LAG1_CLN8 PF03798.11 EDP44608.1 - 2.8e-27 95.5 12.5 3.1e-27 95.4 8.7 1.0 1 0 0 1 1 1 1 TLC domain HMGL-like PF00682.14 EDP44609.1 - 2.2e-63 214.1 0.0 3.5e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Transketolase_N PF00456.16 EDP44610.1 - 1.4e-141 471.1 0.0 2e-141 470.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EDP44610.1 - 6e-44 149.6 0.0 1.1e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDP44610.1 - 1.3e-11 44.5 0.0 3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EDP44610.1 - 0.0023 16.9 0.1 0.012 14.5 0.1 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase NDUFA12 PF05071.11 EDP44611.1 - 2.2e-08 34.5 0.6 3.4e-08 33.9 0.4 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Nuc-transf PF10127.4 EDP44611.1 - 0.029 13.6 2.2 0.041 13.2 1.5 1.1 1 0 0 1 1 1 0 Predicted nucleotidyltransferase PhdYeFM_antitox PF02604.14 EDP44611.1 - 0.13 11.8 2.1 0.21 11.1 1.4 1.3 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Ead_Ea22 PF13935.1 EDP44611.1 - 0.27 11.5 5.3 0.84 9.9 3.7 1.8 1 1 0 1 1 1 0 Ead/Ea22-like protein DUF1018 PF06252.7 EDP44612.1 - 0.012 16.1 0.4 0.032 14.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) GYF PF02213.11 EDP44612.1 - 0.016 14.7 2.1 0.056 13.0 1.5 1.9 1 1 0 1 1 1 0 GYF domain Clp1 PF06807.9 EDP44613.1 - 2.3e-23 82.9 0.0 1.5e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EDP44613.1 - 0.00056 19.6 0.0 0.0019 17.9 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EDP44613.1 - 0.017 15.0 0.0 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EDP44613.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDP44613.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EDP44613.1 - 0.084 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EDP44613.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EDP44613.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.23 EDP44614.1 - 3.4e-43 147.3 0.1 4.3e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_16 PF13432.1 EDP44615.1 - 9e-13 48.5 2.9 0.00035 21.1 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP44615.1 - 2e-11 44.0 7.0 1.4e-05 25.2 0.4 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDP44615.1 - 3e-11 42.3 11.3 0.002 17.8 0.8 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDP44615.1 - 7.4e-11 41.6 9.1 0.13 12.9 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44615.1 - 4.6e-10 38.5 9.4 0.029 14.1 0.1 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDP44615.1 - 8.5e-08 31.7 8.5 0.00013 21.5 1.8 4.0 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EDP44615.1 - 3.4e-07 29.9 5.5 0.031 14.4 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDP44615.1 - 4e-07 30.0 5.2 0.89 10.1 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDP44615.1 - 1.2e-06 27.8 9.7 0.034 13.7 0.5 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EDP44615.1 - 5.1e-05 23.3 6.4 0.011 15.8 3.4 3.5 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDP44615.1 - 0.00017 21.4 0.6 0.037 13.8 0.0 3.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44615.1 - 0.00062 19.6 13.9 0.66 9.9 0.0 4.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 EDP44615.1 - 0.0015 18.6 0.0 0.095 12.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 EDP44615.1 - 0.0021 16.8 1.6 0.013 14.3 0.1 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 EDP44615.1 - 0.0032 17.1 8.7 0.17 11.7 0.2 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDP44615.1 - 0.0051 15.9 0.8 0.0097 14.9 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3808 PF10300.4 EDP44615.1 - 0.01 14.4 1.4 0.043 12.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) ChAPs PF09295.5 EDP44615.1 - 0.096 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.15 EDP44615.1 - 0.14 12.2 0.1 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 PPR repeat TPR_4 PF07721.9 EDP44615.1 - 0.16 12.5 2.8 1e+02 3.7 0.7 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDP44615.1 - 1.1 9.2 9.5 16 5.6 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GIY-YIG PF01541.19 EDP44616.1 - 2.9e-06 27.5 0.0 9.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain OrfB_Zn_ribbon PF07282.6 EDP44616.1 - 0.074 12.7 1.4 0.27 10.8 0.1 2.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-HC5HC2H PF13771.1 EDP44616.1 - 0.15 12.1 4.1 0.32 11.1 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.2 EDP44616.1 - 0.15 12.1 6.8 0.38 10.8 4.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger C1_3 PF07649.7 EDP44616.1 - 0.19 11.7 5.5 0.53 10.3 3.8 1.8 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 EDP44616.1 - 3.4 7.4 7.2 7 6.4 5.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 EDP44616.1 - 4.4 7.2 13.9 2.1 8.2 7.9 1.8 2 0 0 2 2 2 0 Ring finger domain Arm PF00514.18 EDP44617.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 EDP44618.1 - 7.3e-36 123.6 0.0 1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44618.1 - 2.6e-28 98.7 0.0 3.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44618.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Mem_trans PF03547.13 EDP44620.1 - 1.2e-28 99.5 2.6 4.1e-28 97.7 1.8 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF726 PF05277.7 EDP44621.1 - 5.8e-100 334.5 0.0 8.3e-100 334.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 EDP44621.1 - 0.00071 19.1 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP44621.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.23 EDP44622.1 - 3.9e-95 319.2 1.1 4.4e-95 319.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 EDP44623.1 - 2.1e-26 90.8 10.7 1.1e-06 28.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat SHQ1 PF04925.10 EDP44624.1 - 4.5e-28 98.0 0.8 1.1e-27 96.7 0.6 1.5 1 1 0 1 1 1 1 SHQ1 protein Ribosomal_S15 PF00312.17 EDP44625.1 - 3.9e-17 61.7 0.2 8.5e-17 60.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 MEKHLA PF08670.6 EDP44625.1 - 0.032 13.7 0.1 2.3 7.7 0.0 2.9 3 0 0 3 3 3 0 MEKHLA domain TMF_TATA_bd PF12325.3 EDP44625.1 - 0.046 13.4 1.0 2.8 7.6 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BDV_P24 PF06595.6 EDP44625.1 - 0.085 12.6 0.6 0.2 11.3 0.4 1.6 1 0 0 1 1 1 0 Borna disease virus P24 protein EXS PF03124.9 EDP44626.1 - 7.9e-87 291.4 22.9 1e-86 291.1 15.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EDP44626.1 - 1.4e-31 110.2 0.1 2.5e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 SPX domain Vps51 PF08700.6 EDP44627.1 - 2.4e-14 52.9 1.1 5e-14 51.9 0.8 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EDP44627.1 - 5.1e-06 26.3 0.3 1.2e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dopey_N PF04118.9 EDP44628.1 - 1.9e-102 342.2 0.4 1.6e-101 339.1 0.0 2.5 2 0 0 2 2 2 1 Dopey, N-terminal zf-DBF PF07535.7 EDP44628.1 - 0.05 13.2 0.5 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 DBF zinc finger Urb2 PF10441.4 EDP44628.1 - 2 7.9 10.6 0.91 9.0 0.0 4.6 4 0 0 4 4 4 0 Urb2/Npa2 family Oxysterol_BP PF01237.13 EDP44629.1 - 3.8e-113 377.5 0.0 4.5e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein YL1 PF05764.8 EDP44629.1 - 1.3 8.5 8.2 2.2 7.8 2.5 2.1 2 0 0 2 2 2 0 YL1 nuclear protein PH_8 PF15409.1 EDP44630.1 - 2.5e-16 59.5 0.1 4.4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDP44630.1 - 0.0013 18.9 0.1 0.0031 17.7 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDP44630.1 - 0.02 15.0 0.3 0.081 13.1 0.2 1.9 1 1 0 1 1 1 0 PH domain RabGAP-TBC PF00566.13 EDP44631.1 - 3e-20 72.6 0.5 3e-20 72.6 0.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TACC PF05010.9 EDP44631.1 - 0.0055 16.4 2.2 0.0085 15.8 1.5 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Microtub_assoc PF07989.6 EDP44631.1 - 0.0096 15.7 9.4 0.031 14.0 2.5 2.8 2 1 1 3 3 3 2 Microtubule associated DUF2972 PF11186.3 EDP44631.1 - 0.029 14.2 0.2 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) CDC27 PF09507.5 EDP44632.1 - 3.4 6.7 21.7 4.4 6.4 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 bZIP_1 PF00170.16 EDP44633.1 - 1.6e-06 27.9 16.2 2.3e-06 27.4 10.7 1.6 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDP44633.1 - 0.00044 20.0 10.9 0.00044 20.0 7.5 1.7 1 1 1 2 2 2 1 Basic region leucine zipper Mnd1 PF03962.10 EDP44633.1 - 1.6 8.3 8.0 2.5 7.7 5.5 1.2 1 0 0 1 1 1 0 Mnd1 family TraV PF09676.5 EDP44633.1 - 5.1 7.8 9.5 0.77 10.4 0.6 2.6 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Ribosomal_S8e PF01201.17 EDP44634.1 - 3e-49 166.5 0.6 3.6e-49 166.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SurE PF01975.12 EDP44635.1 - 3.9e-08 32.8 0.0 3.9e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 EDP44635.1 - 0.044 13.9 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain WD40 PF00400.27 EDP44636.1 - 1.7e-48 160.7 20.5 2.1e-07 30.5 0.1 9.4 9 0 0 9 9 9 9 WD domain, G-beta repeat Utp12 PF04003.7 EDP44636.1 - 9.9e-21 73.7 0.6 1.9e-20 72.8 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EDP44636.1 - 5.7e-05 21.4 0.0 0.00018 19.7 0.0 1.9 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP44636.1 - 0.019 13.7 0.0 2.8 6.5 0.0 3.4 2 2 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 EDP44636.1 - 0.025 13.6 0.0 0.93 8.5 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EDP44636.1 - 0.15 11.2 0.0 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.1 EDP44636.1 - 0.51 10.6 3.9 18 5.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Oxysterol_BP PF01237.13 EDP44638.1 - 4.6e-70 235.8 0.0 5.9e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PI3_PI4_kinase PF00454.22 EDP44639.1 - 1.3e-50 172.0 0.0 2.2e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EDP44639.1 - 3.6e-24 85.4 0.0 6.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EDP44639.1 - 6.4e-15 55.0 0.0 2.3e-14 53.2 0.0 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EDP44639.1 - 8.2e-09 34.7 0.1 2.4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EDP44639.1 - 4.9e-06 26.1 0.4 0.61 9.7 0.0 4.4 3 1 2 5 5 5 3 TPR repeat DUF3385 PF11865.3 EDP44639.1 - 0.0055 16.6 1.9 3.1 7.6 0.2 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) Porphobil_deam PF01379.15 EDP44640.1 - 3.8e-68 228.6 0.0 3.3e-65 219.0 0.0 2.2 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EDP44640.1 - 1.2e-14 54.1 0.1 7.9e-14 51.5 0.1 2.2 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain WD40 PF00400.27 EDP44641.1 - 2.3e-09 36.7 0.0 0.0046 16.7 0.0 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ PF01011.16 EDP44641.1 - 0.019 14.5 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Peptidase_M23 PF01551.17 EDP44642.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M23 CBF PF03914.12 EDP44643.1 - 6.2e-35 120.0 0.8 1.2e-34 119.1 0.1 1.8 2 0 0 2 2 2 1 CBF/Mak21 family DUF711 PF05167.7 EDP44643.1 - 0.034 12.8 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Methyltransf_26 PF13659.1 EDP44644.1 - 1.2e-06 28.5 0.2 1.9e-05 24.6 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDP44644.1 - 0.00048 19.5 0.0 0.0093 15.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain TFIID_20kDa PF03847.8 EDP44645.1 - 4.4e-33 113.3 0.6 8e-33 112.5 0.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EDP44645.1 - 0.0014 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP44645.1 - 0.0082 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ycf1 PF05758.7 EDP44645.1 - 0.031 12.0 16.8 0.044 11.5 11.7 1.3 1 0 0 1 1 1 0 Ycf1 PDZ_2 PF13180.1 EDP44645.1 - 0.071 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Plasmodium_Vir PF05795.6 EDP44645.1 - 2.9 6.9 6.8 5.4 6.1 4.7 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.10 EDP44645.1 - 3.6 6.1 14.3 7 5.2 9.9 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) YjgP_YjgQ PF03739.9 EDP44645.1 - 7.1 5.2 11.3 11 4.6 7.8 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CoaE PF01121.15 EDP44646.1 - 9.1e-39 132.7 0.0 1.1e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EDP44646.1 - 2e-05 25.3 0.0 2.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP44646.1 - 0.0028 17.9 0.0 0.0028 17.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP44646.1 - 0.005 16.7 0.0 0.0075 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiG_C PF01890.11 EDP44646.1 - 0.059 13.6 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus AAA_28 PF13521.1 EDP44646.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EDP44646.1 - 0.14 11.8 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase WD40 PF00400.27 EDP44647.1 - 2.1e-08 33.6 3.5 0.0025 17.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP44647.1 - 0.089 13.0 0.5 98 3.4 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Pyr_redox_2 PF07992.9 EDP44648.1 - 1.9e-41 142.1 0.8 3.6e-41 141.2 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDP44648.1 - 8.8e-30 102.9 0.4 2e-29 101.7 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDP44648.1 - 1.7e-21 76.4 3.8 4.8e-18 65.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP44648.1 - 1e-15 58.3 1.3 4.1e-08 33.5 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP44648.1 - 8e-09 34.4 5.5 0.00065 18.2 1.4 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 EDP44648.1 - 6.2e-08 32.1 0.8 1.1e-07 31.3 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDP44648.1 - 7.9e-07 28.2 2.6 7.9e-06 24.9 0.3 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EDP44648.1 - 0.0003 19.7 0.2 0.00089 18.2 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EDP44648.1 - 0.00033 19.6 0.0 0.0041 16.1 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EDP44648.1 - 0.00087 18.4 0.3 0.0021 17.2 0.2 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EDP44648.1 - 0.0016 18.4 4.3 0.0016 18.4 3.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EDP44648.1 - 0.01 16.1 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 EDP44648.1 - 0.01 14.7 0.3 0.01 14.7 0.2 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDP44648.1 - 0.17 10.8 1.8 1.9 7.4 0.8 2.2 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EDP44648.1 - 0.66 9.6 4.1 1.9 8.1 0.0 2.5 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EDP44648.1 - 3 7.6 8.2 0.17 11.6 0.2 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding TFIID-18kDa PF02269.11 EDP44649.1 - 5.6e-17 61.3 0.4 3.4e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit RPAP1_C PF08620.5 EDP44650.1 - 2e-21 75.6 0.2 5.6e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal HEAT PF02985.17 EDP44650.1 - 0.08 13.0 2.7 13 6.1 0.3 3.1 2 0 0 2 2 2 0 HEAT repeat TRAPPC10 PF12584.3 EDP44651.1 - 1e-24 86.7 0.0 2.6e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 KAAG1 PF15354.1 EDP44651.1 - 0.051 13.9 0.5 6 7.2 0.0 3.2 2 1 1 3 3 3 0 Kidney-associated antigen 1 Proteasome PF00227.21 EDP44652.1 - 9e-55 184.9 0.1 1.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDP44652.1 - 2e-14 52.5 0.8 2.7e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ENTH PF01417.15 EDP44653.1 - 3.3e-29 101.2 0.1 5e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EDP44653.1 - 0.046 12.4 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 ANTH domain PAT1 PF09770.4 EDP44653.1 - 6.7 4.8 7.6 9.7 4.2 5.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M50 PF02163.17 EDP44654.1 - 3.9e-06 25.9 0.1 4.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 PAP_central PF04928.12 EDP44655.1 - 1.1e-105 352.0 0.0 1.3e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EDP44655.1 - 2e-39 134.6 0.0 2.9e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDP44655.1 - 3.7e-09 36.7 0.0 8.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EDP44655.1 - 0.016 15.2 0.0 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase beta palm zf-C3HC4_3 PF13920.1 EDP44659.1 - 2.4e-08 33.5 6.4 2.5e-05 23.8 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP44659.1 - 1.3e-07 31.2 6.0 1.5e-06 27.9 1.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP44659.1 - 4e-07 29.9 7.5 8.3e-07 28.9 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP44659.1 - 1.3e-06 27.9 6.4 2.4e-06 27.1 2.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44659.1 - 3.7e-06 26.5 6.9 1.4e-05 24.7 2.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDP44659.1 - 0.03 14.0 4.1 0.03 14.0 2.8 2.6 3 0 0 3 3 3 0 RING-type zinc-finger FdhE PF04216.7 EDP44659.1 - 0.031 13.9 0.2 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF1644 PF07800.7 EDP44659.1 - 0.052 13.4 0.6 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) DUF2685 PF10886.3 EDP44659.1 - 0.41 10.6 3.5 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Peptidase_M16_C PF05193.16 EDP44660.1 - 8.6e-44 149.4 0.0 2e-40 138.4 0.0 2.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDP44660.1 - 2.6e-30 105.1 0.4 5.8e-30 104.0 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EDP44660.1 - 0.05 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated ATP-synt_C PF00137.16 EDP44661.1 - 3e-28 97.5 29.1 6.4e-17 61.2 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Aconitase PF00330.15 EDP44662.1 - 7.5e-179 595.0 0.0 9.2e-179 594.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDP44662.1 - 1.8e-42 144.5 0.0 3.7e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNase_PH PF01138.16 EDP44663.1 - 2.4e-14 53.7 0.0 4.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDP44663.1 - 0.00027 20.8 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 FHA PF00498.21 EDP44664.1 - 2.2e-09 37.3 0.2 4.6e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Homeobox_KN PF05920.6 EDP44665.1 - 2.7e-16 58.9 0.1 2.7e-16 58.9 0.1 2.2 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 EDP44665.1 - 0.00058 19.4 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Ribosomal_L23eN PF03939.8 EDP44666.1 - 5.7e-20 71.0 8.4 5.7e-20 71.0 5.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EDP44666.1 - 1.1e-17 63.7 0.7 2.2e-17 62.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Abhydrolase_6 PF12697.2 EDP44667.1 - 1.2e-12 48.2 0.0 2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44667.1 - 4.2e-09 36.3 0.0 3.9e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP44667.1 - 7.6e-07 28.9 0.0 2.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EDP44667.1 - 0.0079 15.5 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EDP44667.1 - 0.036 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dynamin_N PF00350.18 EDP44668.1 - 2.4e-19 69.7 0.0 7.4e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EDP44668.1 - 1.9e-10 40.7 0.0 2.3e-09 37.2 0.0 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDP44668.1 - 8.7e-09 35.0 0.5 1.4e-07 31.1 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDP44668.1 - 1.8e-05 25.2 0.2 0.018 15.5 0.0 2.8 1 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EDP44668.1 - 4e-05 22.8 0.2 0.00015 20.9 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2533 PF10752.4 EDP44668.1 - 0.00013 22.2 1.9 0.0097 16.1 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2533) cobW PF02492.14 EDP44668.1 - 0.00019 20.9 0.0 0.018 14.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EDP44668.1 - 0.0014 17.9 0.2 2.2 7.5 0.0 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B AAA_29 PF13555.1 EDP44668.1 - 0.0018 17.7 0.0 0.005 16.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDP44668.1 - 0.0041 16.6 0.1 0.88 9.0 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family Arf PF00025.16 EDP44668.1 - 0.0062 15.7 0.4 3.8 6.7 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Septin PF00735.13 EDP44668.1 - 0.012 14.5 0.1 0.036 13.0 0.0 1.7 2 0 0 2 2 2 0 Septin IIGP PF05049.8 EDP44668.1 - 0.015 14.1 0.0 0.044 12.6 0.0 1.7 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.4 EDP44668.1 - 0.046 13.2 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EDP44668.1 - 0.079 12.3 0.0 0.25 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4158 PF13700.1 EDP44669.1 - 0.05 13.0 0.2 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Formyl_trans_N PF00551.14 EDP44670.1 - 9.5e-35 119.7 0.0 9.7e-18 64.3 0.0 2.4 2 0 0 2 2 2 2 Formyl transferase ABC_membrane PF00664.18 EDP44671.1 - 2.9e-99 331.9 31.3 8.5e-53 179.5 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDP44671.1 - 5.9e-71 237.1 0.0 1.2e-34 119.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDP44671.1 - 2e-13 50.0 0.2 0.0006 19.0 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDP44671.1 - 1.1e-11 45.3 0.0 0.012 15.6 0.0 4.4 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 EDP44671.1 - 6.2e-10 38.2 0.1 0.00042 19.0 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EDP44671.1 - 1.8e-07 30.5 2.6 0.001 18.5 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDP44671.1 - 6.1e-07 30.2 0.0 0.03 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDP44671.1 - 8.3e-07 28.3 0.0 0.012 14.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDP44671.1 - 1.6e-06 28.2 5.0 0.0076 16.2 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDP44671.1 - 4.7e-06 26.7 2.3 0.047 13.8 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDP44671.1 - 1.5e-05 24.4 0.1 0.097 12.0 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EDP44671.1 - 1.8e-05 24.4 0.1 1.6 8.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EDP44671.1 - 2.5e-05 24.1 0.1 0.042 13.6 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EDP44671.1 - 3.2e-05 23.7 4.3 0.15 12.0 0.2 3.9 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EDP44671.1 - 0.00015 21.9 0.1 3.3 7.9 0.0 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDP44671.1 - 0.00028 20.4 0.2 1.4 8.3 0.0 3.3 4 0 0 4 4 4 2 AAA-like domain AAA_30 PF13604.1 EDP44671.1 - 0.00065 19.3 0.1 1.6 8.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EDP44671.1 - 0.0014 18.9 0.0 1.2 9.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EDP44671.1 - 0.0018 17.4 0.0 0.23 10.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EDP44671.1 - 0.0024 18.2 0.4 0.18 12.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP44671.1 - 0.003 17.4 0.0 1.4 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EDP44671.1 - 0.0035 16.1 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 EDP44671.1 - 0.0065 15.9 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family APS_kinase PF01583.15 EDP44671.1 - 0.025 14.2 0.1 3.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EDP44671.1 - 0.044 13.9 0.0 15 5.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 EDP44671.1 - 0.055 12.3 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 EDP44671.1 - 0.059 13.3 0.0 15 5.5 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase PRK PF00485.13 EDP44671.1 - 0.069 12.7 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EDP44671.1 - 0.076 12.7 0.1 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EDP44671.1 - 0.11 11.2 0.1 3.1 6.3 0.1 2.4 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EDP44671.1 - 0.14 12.0 0.2 12 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDP44671.1 - 0.74 8.7 0.0 9.1 5.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain EF-hand_7 PF13499.1 EDP44672.1 - 5.4e-10 39.2 1.1 6.8e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EDP44672.1 - 4.4e-07 29.2 0.0 0.048 13.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EDP44672.1 - 6.6e-07 28.1 0.0 0.00093 18.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EDP44672.1 - 2.3e-06 26.6 0.0 0.00019 20.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDP44672.1 - 8.4e-05 22.1 0.1 0.0066 16.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair Glycos_transf_3 PF00591.16 EDP44673.1 - 3.8e-66 223.0 0.0 6.5e-65 219.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EDP44673.1 - 0.0017 17.8 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain EF-hand_1 PF00036.27 EDP44674.1 - 1.4e-25 86.6 6.3 7.6e-08 31.1 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EDP44674.1 - 3.5e-21 75.0 0.2 6.5e-13 48.6 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EDP44674.1 - 3.9e-20 69.8 2.4 1.6e-06 27.5 0.0 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 EDP44674.1 - 3.7e-16 58.4 4.2 5.2e-07 29.1 0.2 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EDP44674.1 - 3.1e-14 51.5 8.0 8.7e-05 21.6 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_4 PF12763.2 EDP44674.1 - 5.1e-09 35.8 1.4 0.0071 16.0 0.0 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EDP44674.1 - 0.00066 19.5 0.9 0.16 11.9 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EDP44674.1 - 0.0007 19.6 0.3 1.5 8.8 0.0 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DAG_kinase_N PF14513.1 EDP44674.1 - 0.12 12.5 0.2 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus AAA_11 PF13086.1 EDP44675.1 - 3.5e-58 196.9 0.0 1.5e-57 194.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDP44675.1 - 1.1e-57 194.6 0.0 2e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP44675.1 - 1.5e-12 47.0 2.2 1.4e-11 43.9 0.5 2.9 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EDP44675.1 - 3.4e-11 43.1 0.2 0.0007 19.1 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EDP44675.1 - 1.5e-09 37.6 0.4 4.2e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDP44675.1 - 3.5e-05 23.9 0.1 0.0014 18.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EDP44675.1 - 5.3e-05 22.7 0.0 0.00035 20.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family UvrD-helicase PF00580.16 EDP44675.1 - 0.0002 20.7 0.0 0.0004 19.7 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EDP44675.1 - 0.00041 19.8 0.1 0.0012 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EDP44675.1 - 0.00048 19.2 0.1 0.18 10.7 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 EDP44675.1 - 0.0017 18.4 0.1 0.0052 16.8 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EDP44675.1 - 0.0021 18.1 2.4 0.0036 17.3 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EDP44675.1 - 0.0022 17.6 0.0 0.021 14.4 0.0 2.4 3 0 0 3 3 3 1 Helicase AAA PF00004.24 EDP44675.1 - 0.0023 18.1 0.0 0.0078 16.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EDP44675.1 - 0.0025 17.6 0.0 0.044 13.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EDP44675.1 - 0.0067 16.1 0.0 0.029 14.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 EDP44675.1 - 0.0071 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EDP44675.1 - 0.0095 16.7 0.3 0.026 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP44675.1 - 0.014 15.2 0.5 0.041 13.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 EDP44675.1 - 0.019 14.1 0.0 0.84 8.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EDP44675.1 - 0.022 13.6 0.0 0.073 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD_C PF13361.1 EDP44675.1 - 0.033 13.6 0.2 0.17 11.3 0.1 2.1 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.17 EDP44675.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.24 EDP44675.1 - 0.087 12.3 0.1 0.25 10.8 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 EDP44675.1 - 0.093 12.4 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EDP44675.1 - 0.1 12.3 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDP44675.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDP44675.1 - 0.14 11.6 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain ETF PF01012.16 EDP44676.1 - 1.3e-35 122.5 1.5 1.9e-35 122.0 1.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EFG_C PF00679.19 EDP44676.1 - 0.14 12.0 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor G C-terminus Mito_carr PF00153.22 EDP44677.1 - 2.2e-28 97.7 0.3 2.5e-15 55.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Glycos_transf_1 PF00534.15 EDP44678.1 - 2.9e-14 52.8 0.0 5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDP44678.1 - 1.3e-05 25.4 0.1 0.00018 21.6 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDP44678.1 - 0.026 14.2 1.0 0.27 10.9 0.7 2.2 1 1 0 1 1 1 0 Glycosyltransferase Family 4 PI3Ka PF00613.15 EDP44679.1 - 1.1e-44 151.8 1.1 1.8e-44 151.1 0.8 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EDP44679.1 - 9.6e-42 143.0 0.0 1.3e-39 136.0 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EDP44679.1 - 4.7e-28 97.7 0.0 7.9e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF869 PF05911.6 EDP44679.1 - 0.048 11.8 0.3 0.07 11.3 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) tRNA_int_endo PF01974.12 EDP44680.1 - 2.1e-16 59.4 0.0 3.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PGM_PMM_I PF02878.11 EDP44681.1 - 8.6e-36 122.4 0.1 1.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDP44681.1 - 4.4e-27 94.3 0.0 1.1e-26 93.0 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EDP44681.1 - 1.7e-15 57.1 0.0 4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDP44681.1 - 2.1e-09 37.2 0.0 5.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ADH_zinc_N PF00107.21 EDP44682.1 - 2.5e-30 104.6 0.0 4.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDP44682.1 - 9.6e-09 36.2 0.0 4e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP44682.1 - 4.6e-08 32.7 0.0 5.7e-06 26.0 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain PALP PF00291.20 EDP44682.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DsbB PF02600.11 EDP44682.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Pkinase PF00069.20 EDP44683.1 - 1.5e-71 240.6 0.0 1.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44683.1 - 3.9e-30 104.7 0.0 5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDP44683.1 - 2.2e-10 40.8 0.9 8.1e-10 39.0 0.4 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDP44683.1 - 0.00044 19.2 0.0 0.00084 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP44683.1 - 0.017 14.2 0.1 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP44683.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NOT2_3_5 PF04153.13 EDP44684.1 - 2.6e-36 124.4 0.9 4.1e-36 123.8 0.7 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Chorismate_synt PF01264.16 EDP44686.1 - 1.6e-136 454.3 0.1 1.8e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase LSM14 PF12701.2 EDP44687.1 - 0.11 12.3 0.1 0.64 9.8 0.1 2.0 2 0 0 2 2 2 0 Scd6-like Sm domain Gti1_Pac2 PF09729.4 EDP44688.1 - 8.6e-43 146.1 0.2 9.5e-34 116.6 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family Histone PF00125.19 EDP44689.1 - 1.8e-30 104.8 0.9 2.7e-30 104.2 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDP44689.1 - 0.00077 19.6 0.1 0.0013 18.9 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDP44689.1 - 0.011 15.7 0.2 0.074 13.1 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3305 PF11749.3 EDP44689.1 - 0.055 13.3 0.0 0.13 12.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3305) CENP-T PF15511.1 EDP44689.1 - 0.068 12.4 0.1 0.082 12.1 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC73 PF05179.9 EDP44690.1 - 3e-31 108.8 0.0 5.4e-28 98.1 0.0 2.3 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family Oxidored_FMN PF00724.15 EDP44692.1 - 1.4e-60 205.1 0.0 1.9e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Chs3p PF12271.3 EDP44694.1 - 5.4e-79 265.2 21.3 6.2e-79 265.0 14.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3671 PF12420.3 EDP44694.1 - 1 9.3 18.0 0.36 10.8 3.8 3.3 3 1 0 3 3 3 0 Protein of unknown function Septin PF00735.13 EDP44695.1 - 2.3e-100 335.2 0.1 4.4e-100 334.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDP44695.1 - 5.6e-06 26.2 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EDP44695.1 - 2.8e-05 24.0 0.0 7.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP44695.1 - 5.5e-05 23.9 0.2 0.00029 21.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDP44695.1 - 9.2e-05 22.3 3.0 0.13 12.1 0.0 2.7 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 EDP44695.1 - 0.00088 19.4 0.0 0.0022 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDP44695.1 - 0.0011 18.1 0.4 0.0036 16.4 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EDP44695.1 - 0.0023 17.0 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EDP44695.1 - 0.004 17.6 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EDP44695.1 - 0.0055 15.5 0.1 0.0092 14.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF87 PF01935.12 EDP44695.1 - 0.0067 16.2 0.6 0.26 11.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EDP44695.1 - 0.0074 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EDP44695.1 - 0.015 14.7 0.0 0.065 12.6 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EDP44695.1 - 0.018 14.9 1.2 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDP44695.1 - 0.024 14.9 2.6 0.072 13.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EDP44695.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EDP44695.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EDP44695.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EDP44695.1 - 0.1 12.9 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 1 0 ABC transporter PduV-EutP PF10662.4 EDP44695.1 - 0.17 11.3 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EDP44695.1 - 0.18 11.1 0.3 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Ras family 2-Hacid_dh PF00389.25 EDP44696.1 - 0.0043 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EDP44697.1 - 5.5e-48 162.4 0.0 7.4e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EDP44697.1 - 3.6e-05 23.6 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EDP44697.1 - 0.0033 17.0 0.2 0.45 10.1 0.1 2.9 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EDP44697.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MRP-S25 PF13741.1 EDP44698.1 - 5.9e-16 58.6 1.9 8.7e-16 58.0 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Maf PF02545.9 EDP44699.1 - 1.4e-40 138.5 0.0 1.6e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NOC3p PF07540.6 EDP44699.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 Nucleolar complex-associated protein PP_kinase PF02503.12 EDP44700.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Zn_clus PF00172.13 EDP44701.1 - 8.2e-06 25.6 9.8 1.4e-05 24.9 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3038 PF11237.3 EDP44701.1 - 0.0011 18.8 1.0 0.0023 17.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3038) Fungal_trans PF04082.13 EDP44701.1 - 0.016 14.0 0.3 0.027 13.3 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain E1-E2_ATPase PF00122.15 EDP44702.1 - 1.4e-55 187.8 1.2 3.3e-55 186.6 0.9 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDP44702.1 - 7.3e-45 152.7 2.7 7.3e-45 152.7 1.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDP44702.1 - 2.8e-21 76.9 0.0 5.7e-20 72.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP44702.1 - 5.2e-17 61.5 0.0 2e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDP44702.1 - 7.5e-13 49.0 0.0 7.6e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDP44702.1 - 1.7e-12 46.5 0.1 6.3e-12 44.7 0.1 2.1 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDP44702.1 - 0.0016 18.1 1.1 0.0025 17.4 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EDP44703.1 - 4.4e-58 191.2 19.9 1.8e-11 43.4 2.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDP44703.1 - 0.0004 19.8 0.0 8.4 5.9 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EDP44703.1 - 0.0055 16.4 0.1 2.5 7.7 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CTK3 PF12243.3 EDP44704.1 - 1.8e-35 121.5 0.7 2e-35 121.4 0.5 1.0 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF1749 PF08538.5 EDP44705.1 - 0.0074 15.2 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) RRM_1 PF00076.17 EDP44706.1 - 7.1e-61 201.7 0.0 3.3e-18 65.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44706.1 - 2e-49 165.4 0.0 1.1e-14 54.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44706.1 - 1.1e-16 60.4 0.0 0.00042 20.1 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDP44706.1 - 0.0016 18.1 0.0 4.8 7.0 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif ELFV_dehydrog PF00208.16 EDP44707.1 - 1.7e-52 178.4 0.0 6e-52 176.6 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EDP44707.1 - 5.6e-22 77.1 0.0 1.5e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EDP44707.1 - 0.0095 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Transket_pyr PF02779.19 EDP44708.1 - 1.4e-62 210.3 0.0 2.3e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EDP44708.1 - 4.9e-59 199.5 0.0 7.2e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TetR_N PF00440.18 EDP44708.1 - 0.057 13.0 0.0 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Synaptobrevin PF00957.16 EDP44709.1 - 8e-32 108.7 1.4 1e-31 108.3 0.9 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF3357 PF11837.3 EDP44709.1 - 0.0034 17.1 0.3 0.033 14.0 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3357) ODV-E18 PF10717.4 EDP44709.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 RSN1_TM PF13967.1 EDP44709.1 - 0.067 12.7 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Chordopox_A33R PF05966.7 EDP44709.1 - 0.12 11.1 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF912 PF06024.7 EDP44709.1 - 0.17 11.9 2.4 0.84 9.7 1.5 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L22 PF00237.14 EDP44710.1 - 9e-31 105.9 0.0 1.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1749 PF08538.5 EDP44711.1 - 1.4e-53 181.7 0.0 2.6e-53 180.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EDP44711.1 - 6.3e-07 29.5 0.1 8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP44711.1 - 0.0037 17.0 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PTPlike_phytase PF14566.1 EDP44712.1 - 3.1e-121 400.5 1.4 2.4e-42 144.5 0.2 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 EDP44712.1 - 2.5e-07 30.3 0.1 0.47 10.0 0.0 4.2 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EDP44712.1 - 7e-06 26.3 0.1 0.12 12.5 0.1 3.4 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 EDP44712.1 - 2.3e-05 23.8 0.2 1.1 8.5 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 EDP44712.1 - 0.0024 17.7 0.0 10 6.1 0.0 3.5 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha Chitin_synth_1 PF01644.12 EDP44713.1 - 2.8e-79 264.6 0.0 4.5e-79 263.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDP44713.1 - 1.7e-25 88.5 0.0 3.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDP44713.1 - 1.5e-20 73.1 10.6 5.9e-19 67.8 1.7 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EDP44713.1 - 2.1e-06 27.7 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDP44713.1 - 5.6e-06 26.2 18.4 5.6e-06 26.2 12.8 3.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 EF-hand_4 PF12763.2 EDP44714.1 - 1.9e-15 56.4 0.0 3.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EDP44714.1 - 3.5e-08 32.7 0.4 7.8e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 WH2 motif Trypan_PARP PF05887.6 EDP44714.1 - 1.6e-05 24.7 46.8 1.6e-05 24.7 32.4 4.7 2 1 3 5 5 5 1 Procyclic acidic repetitive protein (PARP) EF-hand_7 PF13499.1 EDP44714.1 - 0.00012 22.1 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair SH3_9 PF14604.1 EDP44714.1 - 0.0029 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.27 EDP44715.1 - 2.6e-27 93.6 18.5 3e-07 30.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3337 PF11816.3 EDP44715.1 - 1.8e-18 67.0 0.0 2.8e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Nup160 PF11715.3 EDP44715.1 - 2.2e-05 22.8 3.0 0.68 7.9 0.3 4.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP44715.1 - 0.015 14.0 0.0 0.063 12.0 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Cpn60_TCP1 PF00118.19 EDP44716.1 - 2.2e-119 399.2 0.0 2.7e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EDP44717.1 - 2e-70 236.8 0.0 7.7e-70 235.0 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44717.1 - 6.1e-36 123.8 0.3 4.9e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 EDP44717.1 - 1.5e-16 59.5 0.1 2.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EDP44717.1 - 7.4e-07 28.4 0.1 1.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDP44717.1 - 9.9e-05 21.4 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP44717.1 - 0.016 14.9 0.3 0.065 12.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDP44717.1 - 0.23 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cyt-b5 PF00173.23 EDP44718.1 - 4.9e-25 87.1 0.1 5.4e-25 86.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GTP_cyclohydroI PF01227.17 EDP44719.1 - 4.2e-74 247.6 0.0 4.9e-74 247.4 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EDP44719.1 - 0.00036 20.4 0.0 0.0009 19.1 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 EDP44719.1 - 0.031 14.0 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_L14 PF00238.14 EDP44720.1 - 8.8e-34 115.8 0.0 9.9e-34 115.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Nucleopor_Nup85 PF07575.8 EDP44721.1 - 2.4e-62 210.9 0.1 4.7e-62 209.9 0.1 1.5 1 1 0 1 1 1 1 Nup85 Nucleoporin HA2 PF04408.18 EDP44722.1 - 2.6e-30 104.4 0.0 4.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDP44722.1 - 2.8e-24 85.1 0.0 6.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDP44722.1 - 4e-11 42.6 0.0 7.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 EDP44723.1 - 0.0028 17.9 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EDP44723.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EDP44723.1 - 0.0092 14.9 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EDP44723.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDP44723.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EDP44723.1 - 0.021 15.1 0.8 0.021 15.1 0.5 1.9 1 1 1 2 2 2 0 AAA domain Myosin_head PF00063.16 EDP44723.1 - 0.027 12.5 0.0 0.035 12.1 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) PhoH PF02562.11 EDP44723.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EDP44723.1 - 0.06 13.1 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 EDP44723.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EDP44723.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EDP44723.1 - 0.14 11.8 0.1 0.42 10.2 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase WD40 PF00400.27 EDP44724.1 - 9.1e-20 69.7 3.9 9.6e-09 34.7 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoside_tran PF01733.13 EDP44727.1 - 1.5e-18 67.0 16.1 9.4e-17 61.1 6.7 2.9 2 1 0 2 2 2 2 Nucleoside transporter Acyl_transf_1 PF00698.16 EDP44728.1 - 1.4e-13 50.9 0.1 2.9e-12 46.5 0.0 2.6 3 1 0 3 3 3 1 Acyl transferase domain EMP24_GP25L PF01105.19 EDP44729.1 - 2.1e-15 56.9 0.5 2.4e-15 56.7 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA-synt_1b PF00579.20 EDP44730.1 - 1.3e-61 208.3 0.0 9.4e-61 205.4 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Glyoxalase PF00903.20 EDP44731.1 - 8e-16 58.1 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDP44731.1 - 5.8e-12 46.1 0.0 7.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EDP44731.1 - 2e-07 30.9 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDP44731.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.4 2 0 0 2 2 2 0 Glyoxalase-like domain zf-H2C2_2 PF13465.1 EDP44732.1 - 0.033 14.4 5.0 2 8.8 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDP44732.1 - 0.15 12.4 17.6 0.27 11.6 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDP44732.1 - 0.19 12.1 18.0 0.25 11.7 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type GPI2 PF06432.6 EDP44733.1 - 2.5e-51 174.6 8.2 3.1e-51 174.4 5.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_3 PF07859.8 EDP44734.1 - 2.6e-19 69.6 0.0 5.4e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDP44734.1 - 6e-16 58.0 0.0 8.7e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 EDP44734.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.2 EDP44734.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UCH PF00443.24 EDP44735.1 - 9.3e-36 123.3 0.2 1.2e-35 122.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDP44735.1 - 5.4e-17 62.1 0.0 6.5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.11 EDP44735.1 - 5.5 6.7 8.1 17 5.1 0.7 2.5 2 0 0 2 2 2 0 HIT zinc finger Npa1 PF11707.3 EDP44736.1 - 3.9e-46 157.5 0.0 7e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal ThiF PF00899.16 EDP44737.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family DnaJ-X PF14308.1 EDP44738.1 - 1e-30 106.5 1.0 2e-30 105.6 0.7 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDP44738.1 - 6e-26 89.9 0.8 1.6e-25 88.6 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain DUF3631 PF12307.3 EDP44738.1 - 0.041 13.8 0.9 1.5 8.6 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3631) IBR PF01485.16 EDP44738.1 - 0.067 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 IBR domain VIT1 PF01988.14 EDP44738.1 - 3.7 6.9 6.5 0.22 10.9 0.3 1.8 2 0 0 2 2 2 0 VIT family TFIIS_M PF07500.9 EDP44739.1 - 3.4e-30 104.4 3.8 9.3e-30 103.0 0.7 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EDP44739.1 - 9e-20 70.0 9.0 3e-19 68.3 5.7 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EDP44739.1 - 8.5e-14 50.7 0.5 2.4e-13 49.3 0.3 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Borrelia_REV PF03978.8 EDP44739.1 - 0.016 14.9 1.2 0.097 12.3 0.1 2.4 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF1411 PF07199.6 EDP44739.1 - 0.026 13.9 0.6 0.058 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Baculo_LEF5_C PF11792.3 EDP44739.1 - 0.21 11.0 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_5 PF13719.1 EDP44739.1 - 0.59 9.7 4.6 1.6 8.3 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDP44739.1 - 1.3 8.8 4.7 3.1 7.5 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prp18 PF02840.10 EDP44739.1 - 4.1 7.2 8.1 2.8 7.7 0.3 2.9 3 0 0 3 3 3 0 Prp18 domain CBF PF03914.12 EDP44740.1 - 5.7e-40 136.4 0.0 5.7e-40 136.4 0.0 3.2 3 1 0 3 3 3 1 CBF/Mak21 family Pentaxin PF00354.12 EDP44740.1 - 0.18 11.1 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 Pentaxin family GCD14 PF08704.5 EDP44741.1 - 4.4e-57 193.4 4.9 1.2e-45 155.9 0.5 3.1 2 1 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EDP44741.1 - 3.2e-06 27.1 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP44741.1 - 0.00012 22.6 0.4 0.075 13.6 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EDP44741.1 - 0.0014 18.2 0.0 0.11 12.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 EDP44741.1 - 0.023 15.5 0.0 0.079 13.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 EDP44742.1 - 1.5e-18 67.6 0.2 2e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 EDP44743.1 - 3e-05 23.4 4.8 0.00046 19.6 3.3 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase UBX PF00789.15 EDP44744.1 - 5.8e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 UBX domain CAF-1_p150 PF11600.3 EDP44744.1 - 0.0011 18.3 28.5 0.0016 17.9 19.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C2H2_2 PF12756.2 EDP44744.1 - 0.017 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PLRV_ORF5 PF01690.12 EDP44744.1 - 0.25 10.4 9.4 0.28 10.3 6.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HAUS-augmin3 PF14932.1 EDP44744.1 - 6.3 5.8 11.5 10 5.2 8.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 WD40 PF00400.27 EDP44745.1 - 4.3e-22 77.1 8.2 2.3e-07 30.4 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2844 PF11005.3 EDP44745.1 - 0.017 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) PD40 PF07676.7 EDP44745.1 - 3.2 7.5 7.1 0.39 10.4 0.1 3.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat adh_short PF00106.20 EDP44747.1 - 1e-17 64.5 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP44747.1 - 4.5e-09 36.2 0.0 6.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDP44747.1 - 3.2e-07 30.0 0.0 4.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDP44747.1 - 4.7e-07 29.8 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDP44747.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDP44747.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EDP44748.1 - 1e-17 64.5 0.0 2.4e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDP44748.1 - 5.9e-08 32.5 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDP44748.1 - 5.6e-06 26.2 0.0 7.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDP44748.1 - 0.00022 21.2 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDP44748.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDP44748.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Varsurf_PPLC PF03490.8 EDP44748.1 - 0.11 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Variant-surface-glycoprotein phospholipase C Polysacc_synt_2 PF02719.10 EDP44748.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SDH_alpha PF03313.10 EDP44750.1 - 1.3e-87 293.4 11.3 5.7e-86 288.0 7.8 2.1 1 1 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EDP44750.1 - 1.8e-52 177.6 0.0 3.9e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Nucleoporin_FG PF13634.1 EDP44751.1 - 1.1e-38 132.0 153.7 1.4e-14 54.3 31.8 4.4 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nup54 PF13874.1 EDP44751.1 - 1.4e-20 73.4 3.9 4e-20 71.9 2.7 1.7 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 DUF4200 PF13863.1 EDP44751.1 - 0.021 14.7 1.9 0.023 14.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2246 PF10229.4 EDP44751.1 - 0.31 10.2 13.3 7.2 5.8 0.4 4.6 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2246) Cluap1 PF10234.4 EDP44751.1 - 2.7 7.1 5.0 4.2 6.5 3.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Inositol_P PF00459.20 EDP44752.1 - 9e-68 228.4 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family AAA_25 PF13481.1 EDP44753.1 - 0.00025 20.4 0.0 0.014 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EDP44753.1 - 0.00061 18.9 0.0 0.00096 18.3 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_17 PF13207.1 EDP44753.1 - 0.0029 18.4 0.0 0.0094 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP44753.1 - 0.0033 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP44753.1 - 0.012 15.9 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDP44753.1 - 0.028 14.0 0.0 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EDP44753.1 - 0.033 14.3 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDP44753.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Tyr_Deacylase PF02580.11 EDP44754.1 - 1.2e-43 148.6 0.0 1.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GCIP PF13324.1 EDP44755.1 - 0.0035 16.6 4.5 0.0038 16.4 2.2 1.8 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Adaptin_binding PF10199.4 EDP44755.1 - 0.33 11.2 5.2 0.6 10.3 3.2 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF572 PF04502.8 EDP44756.1 - 7.5e-79 265.2 13.8 8.2e-79 265.1 9.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 EDP44756.1 - 0.0031 17.1 0.5 0.8 9.3 0.0 2.3 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 EDP44756.1 - 0.029 13.8 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EDP44756.1 - 0.051 13.4 0.3 0.11 12.3 0.2 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein Lar_restr_allev PF14354.1 EDP44756.1 - 0.067 13.5 0.8 7.7 6.9 1.4 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar C1_3 PF07649.7 EDP44756.1 - 0.11 12.5 3.6 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 C1-like domain LsmAD PF06741.8 EDP44757.1 - 8.9e-22 76.9 1.9 1.7e-21 76.0 1.3 1.5 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EDP44757.1 - 1.7e-10 40.6 0.0 4.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 EDP44757.1 - 0.09 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 LSM domain Pept_tRNA_hydro PF01195.14 EDP44758.1 - 1.2e-26 93.3 0.0 1.9e-22 79.6 0.0 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase Ku_C PF03730.9 EDP44758.1 - 0.05 14.1 0.0 0.088 13.3 0.0 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm HEAT_2 PF13646.1 EDP44758.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats polyprenyl_synt PF00348.12 EDP44759.1 - 7e-42 143.0 0.1 3.1e-35 121.2 0.0 3.9 2 1 0 2 2 2 2 Polyprenyl synthetase RRM_1 PF00076.17 EDP44760.1 - 7.2e-11 41.5 0.0 2.5e-05 23.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44760.1 - 3e-09 36.7 0.0 3.1e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44760.1 - 1.8e-05 24.4 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EDP44763.1 - 7.1e-55 185.9 0.0 1.5e-53 181.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44763.1 - 5.8e-26 91.1 0.0 3.8e-25 88.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EDP44763.1 - 9.5e-09 35.0 0.0 0.0088 15.9 0.0 3.0 3 0 0 3 3 3 2 PH domain Kinase-like PF14531.1 EDP44763.1 - 5.2e-06 25.6 0.0 9.2e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP44763.1 - 0.00034 20.4 0.9 0.0015 18.3 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP44763.1 - 0.00052 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4112 PF13430.1 EDP44764.1 - 1.2e-22 79.8 0.1 1.5e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Coprogen_oxidas PF01218.13 EDP44765.1 - 1.2e-103 345.7 0.6 2.9e-66 223.0 0.1 2.6 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase IMS_C PF11799.3 EDP44766.1 - 1.7e-05 24.7 0.1 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-Sec23_Sec24 PF04810.10 EDP44766.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger IMS PF00817.15 EDP44767.1 - 0.00036 20.3 0.0 0.039 13.7 0.0 2.2 1 1 1 2 2 2 2 impB/mucB/samB family DUF177 PF02620.12 EDP44767.1 - 0.098 12.6 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 SKIP_SNW PF02731.10 EDP44768.1 - 1.8e-63 212.7 2.9 1.8e-63 212.7 2.0 3.4 4 0 0 4 4 4 1 SKIP/SNW domain AA_permease PF00324.16 EDP44769.1 - 6.9e-128 426.9 34.2 8.3e-128 426.7 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDP44769.1 - 6.2e-36 123.8 39.6 7.5e-36 123.5 27.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDP44770.1 - 2.7e-130 434.9 34.1 3.1e-130 434.7 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDP44770.1 - 2.9e-42 144.6 40.2 4e-42 144.2 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDP44771.1 - 5.5e-113 377.8 37.1 6.2e-113 377.6 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDP44771.1 - 7.8e-39 133.4 39.6 9.9e-39 133.0 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_1 PF04531.8 EDP44771.1 - 0.51 10.4 4.3 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage holin AA_permease PF00324.16 EDP44772.1 - 5e-64 216.3 20.8 6.2e-64 216.0 14.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDP44772.1 - 7.4e-25 87.3 20.3 9e-25 87.0 14.0 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EDP44772.1 - 0.074 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DUF373 PF04123.8 EDP44772.1 - 2.3 7.1 9.0 3 6.7 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Nucleoside_tran PF01733.13 EDP44773.1 - 0.00081 18.6 0.0 0.0009 18.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside transporter PIG-P PF08510.7 EDP44773.1 - 0.003 17.1 0.1 0.004 16.7 0.1 1.3 1 1 0 1 1 1 1 PIG-P AA_permease PF00324.16 EDP44773.1 - 0.016 13.5 0.3 0.019 13.2 0.2 1.0 1 0 0 1 1 1 0 Amino acid permease DUF2074 PF09847.4 EDP44773.1 - 0.02 13.7 0.1 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 Predicted permease (DUF2074) FixQ PF05545.6 EDP44773.1 - 0.27 10.9 1.5 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ AAA_12 PF13087.1 EDP44774.1 - 8.3e-47 159.1 0.0 1.4e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDP44774.1 - 4.6e-38 131.1 3.8 1.3e-19 70.7 0.5 2.8 2 1 1 3 3 3 2 AAA domain Dna2 PF08696.6 EDP44774.1 - 2.8e-34 118.2 0.0 1.1e-33 116.3 0.0 1.9 1 1 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.1 EDP44774.1 - 1.9e-14 53.7 0.0 4e-13 49.4 0.0 2.7 2 2 0 2 2 2 1 AAA domain PDDEXK_1 PF12705.2 EDP44774.1 - 6.1e-11 42.1 0.0 1.7e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EDP44774.1 - 4.4e-08 32.7 4.4 2.3e-06 27.2 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 EDP44774.1 - 2.3e-06 27.3 2.0 0.25 10.8 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EDP44774.1 - 8.3e-06 25.5 0.1 3.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EDP44774.1 - 3e-05 24.1 0.2 7.1e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.12 EDP44774.1 - 3.6e-05 23.7 0.2 0.00044 20.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF83 UvrD_C PF13361.1 EDP44774.1 - 0.001 18.6 0.0 0.46 9.8 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EDP44774.1 - 0.004 17.1 0.4 0.02 14.9 0.1 2.4 2 0 0 2 2 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EDP44774.1 - 0.0094 15.1 0.1 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 EDP44774.1 - 0.014 15.1 0.9 0.025 14.2 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EDP44774.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 SRP54 PF00448.17 EDP44774.1 - 0.033 13.6 0.6 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EDP44774.1 - 0.035 14.2 0.0 1.1 9.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDP44774.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EDP44774.1 - 0.089 12.2 0.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EDP44774.1 - 0.17 12.1 0.0 0.59 10.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Peptidase_M1 PF01433.15 EDP44775.1 - 5.1e-07 29.1 0.0 2.3e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EDP44775.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Bromodomain PF00439.20 EDP44776.1 - 1.7e-57 191.2 0.5 2.6e-20 72.1 0.1 3.6 3 0 0 3 3 3 3 Bromodomain HEAT_2 PF13646.1 EDP44776.1 - 0.0057 16.9 8.7 0.16 12.2 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats U-box PF04564.10 EDP44777.1 - 0.12 12.3 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 U-box domain Asp PF00026.18 EDP44778.1 - 4.5e-62 210.1 8.0 5.6e-62 209.7 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDP44778.1 - 2.5e-07 30.8 1.4 5.6e-07 29.6 0.3 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDP44778.1 - 2.8e-06 27.7 3.4 0.00049 20.5 0.1 3.1 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 EDP44778.1 - 0.013 15.2 0.2 0.57 10.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EDP44778.1 - 0.15 12.0 0.3 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease NTF2 PF02136.15 EDP44779.1 - 3.8e-32 111.1 0.3 4.7e-32 110.8 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain tify PF06200.9 EDP44779.1 - 0.42 9.9 1.9 0.41 9.9 0.2 1.9 2 0 0 2 2 2 0 tify domain FKBP_C PF00254.23 EDP44780.1 - 2.8e-23 81.7 0.0 3.3e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHD PF00628.24 EDP44781.1 - 5e-09 35.7 7.1 8.2e-09 35.0 4.9 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EDP44781.1 - 8.2e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EDP44781.1 - 0.067 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EDP44781.1 - 0.24 10.7 2.9 0.44 9.9 2.0 1.4 1 0 0 1 1 1 0 PHD-finger EF1_GNE PF00736.14 EDP44782.1 - 1.2e-31 108.2 2.9 2.5e-31 107.2 2.0 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDP44782.1 - 2e-11 43.8 2.8 2e-11 43.8 1.9 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EDP44782.1 - 0.00031 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDP44782.1 - 0.01 15.8 0.1 0.068 13.1 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDP44782.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosom_S12_S23 PF00164.20 EDP44783.1 - 6.5e-48 161.1 0.3 8.2e-48 160.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.1 EDP44784.1 - 1.4e-21 76.8 0.2 6.2e-19 68.2 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDP44784.1 - 0.0077 16.4 0.0 1.8 8.8 0.0 3.5 3 0 0 3 3 3 1 PH domain Helicase_IV_N PF12462.3 EDP44785.1 - 0.26 10.9 2.3 0.37 10.4 0.9 1.8 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal HXXSHH PF07586.6 EDP44786.1 - 0.026 13.4 3.0 0.025 13.4 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) DUF16 PF01519.11 EDP44786.1 - 0.15 12.2 0.8 0.26 11.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 GP41 PF00517.12 EDP44786.1 - 0.29 10.6 3.7 0.42 10.1 2.6 1.2 1 0 0 1 1 1 0 Retroviral envelope protein AA_permease_2 PF13520.1 EDP44787.1 - 2.4e-56 191.1 43.5 2.9e-56 190.8 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDP44787.1 - 2.6e-12 45.8 37.3 3.8e-12 45.3 25.9 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_M48 PF01435.13 EDP44788.1 - 5e-31 108.0 0.4 6.9e-30 104.2 0.1 2.3 2 0 0 2 2 2 1 Peptidase family M48 CUT PF02376.10 EDP44788.1 - 0.048 13.4 0.1 0.94 9.3 0.0 2.6 2 0 0 2 2 2 0 CUT domain Pkinase PF00069.20 EDP44789.1 - 2.4e-27 95.7 0.0 2.5e-26 92.3 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44789.1 - 1.4e-12 47.2 0.0 3.3e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44789.1 - 0.0011 17.9 0.0 0.0028 16.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EDP44789.1 - 0.0041 16.8 0.1 0.0041 16.8 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP44789.1 - 0.022 13.8 0.1 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EDP44789.1 - 0.041 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 EDP44790.1 - 5.9e-46 156.0 0.0 1e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP44790.1 - 7.7e-26 89.7 0.0 1.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mgm101p PF06420.7 EDP44791.1 - 8.5e-84 279.0 0.0 1.1e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MFS_1 PF07690.11 EDP44792.1 - 3.7e-22 78.5 35.9 5.5e-17 61.5 12.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP44792.1 - 2e-17 62.9 19.5 4.9e-16 58.3 1.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1212 PF06738.7 EDP44792.1 - 0.018 14.4 0.6 0.018 14.4 0.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1212) ESSS PF10183.4 EDP44792.1 - 1.4 9.3 5.1 0.84 10.0 0.1 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MRP-L20 PF12824.2 EDP44793.1 - 4.4e-36 124.3 2.9 1.1e-35 123.0 2.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 EDP44793.1 - 1.6e-07 31.3 0.0 4.8e-07 29.8 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDP44793.1 - 3.8e-06 26.7 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EDP44793.1 - 0.0012 17.8 0.5 0.014 14.3 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDP44793.1 - 0.0035 17.4 0.1 0.091 12.8 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDP44793.1 - 0.0099 14.9 0.0 0.99 8.3 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EDP44793.1 - 0.021 13.6 0.7 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 EDP44793.1 - 0.093 11.6 0.2 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HTH_11 PF08279.7 EDP44793.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain Copper-fist PF00649.13 EDP44794.1 - 1.7e-11 43.1 0.8 1.7e-11 43.1 0.5 2.8 3 0 0 3 3 3 1 Copper fist DNA binding domain TPR_14 PF13428.1 EDP44795.1 - 1.8e-18 65.3 16.4 0.0045 17.5 0.0 10.4 4 3 8 12 12 11 3 Tetratricopeptide repeat HAT PF02184.11 EDP44795.1 - 3.4e-15 55.4 63.8 3.3e-09 36.3 0.6 14.3 16 0 0 16 16 16 5 HAT (Half-A-TPR) repeat Suf PF05843.9 EDP44795.1 - 4e-12 46.4 12.7 0.059 13.0 0.0 7.1 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EDP44795.1 - 3.2e-11 43.4 0.0 0.095 13.0 0.0 6.2 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDP44795.1 - 4e-08 33.7 9.6 0.002 18.7 0.0 5.9 6 1 0 7 7 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDP44795.1 - 1.4e-07 31.0 0.9 0.098 12.3 0.0 6.1 4 3 2 6 6 6 1 TPR repeat TPR_2 PF07719.12 EDP44795.1 - 3.2e-05 23.4 8.9 0.62 10.1 0.0 7.6 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDP44795.1 - 7.2e-05 22.6 0.6 0.39 11.0 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDP44795.1 - 0.00021 21.1 5.2 16 5.4 0.0 6.1 5 1 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 EDP44795.1 - 0.00028 20.1 1.2 0.0016 17.6 0.1 2.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP NRDE-2 PF08424.5 EDP44795.1 - 0.0015 17.4 9.9 1.3 7.8 1.3 4.5 2 1 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_7 PF13176.1 EDP44795.1 - 0.0036 16.9 8.2 3.6 7.6 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP44795.1 - 0.013 15.2 0.0 1.1 9.2 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDP44795.1 - 0.018 14.6 0.0 21 4.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EDP44795.1 - 0.019 14.7 11.3 0.2 11.4 0.3 5.3 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 CTP_transf_1 PF01148.15 EDP44796.1 - 1.2e-12 48.0 6.0 2.7e-10 40.3 1.2 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DctQ PF04290.7 EDP44796.1 - 0.024 14.3 1.7 0.024 14.3 1.2 1.8 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-CCHC PF00098.18 EDP44797.1 - 4.1e-11 42.2 14.4 1.2e-06 28.1 1.1 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 EDP44797.1 - 8.7e-06 25.0 19.0 0.0098 15.3 5.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) KH_1 PF00013.24 EDP44797.1 - 1.8e-05 24.2 0.4 3.1e-05 23.5 0.3 1.3 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EDP44797.1 - 3.2e-05 23.5 12.4 0.00022 20.8 2.0 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EDP44797.1 - 0.00032 20.2 0.1 0.00067 19.2 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_5 PF14787.1 EDP44797.1 - 0.98 8.9 13.7 0.034 13.6 1.5 3.0 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger Mis12 PF05859.7 EDP44798.1 - 9.4e-15 54.6 0.3 2.7e-14 53.1 0.1 1.9 2 0 0 2 2 2 1 Mis12 protein Proteasome PF00227.21 EDP44799.1 - 1.6e-33 115.6 0.0 1.9e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Adap_comp_sub PF00928.16 EDP44800.1 - 2.5e-26 92.3 0.0 3.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family TFIID-31kDa PF02291.10 EDP44801.1 - 6.4e-08 32.4 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit RRF PF01765.14 EDP44802.1 - 6.1e-32 110.3 2.2 8.1e-32 109.9 1.5 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF1003 PF06210.6 EDP44802.1 - 1.2 9.0 4.0 56 3.7 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Slu7 PF11708.3 EDP44803.1 - 3.6e-72 242.9 24.1 2.5e-71 240.1 16.7 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor Sigma70_ner PF04546.8 EDP44803.1 - 0.0036 16.9 8.7 0.0073 15.9 6.0 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3245 PF11595.3 EDP44803.1 - 2.6 8.3 13.5 0.28 11.4 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Pkinase PF00069.20 EDP44804.1 - 1.4e-70 237.3 0.0 1.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44804.1 - 1.2e-28 99.8 0.0 1.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L44 PF00935.14 EDP44805.1 - 5.3e-33 112.8 9.7 6.9e-33 112.4 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Amino_oxidase PF01593.19 EDP44806.1 - 1.9e-11 43.7 0.0 1.5e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDP44806.1 - 7.8e-10 38.6 0.3 1.4e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDP44806.1 - 6.3e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDP44806.1 - 0.0064 16.3 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDP44806.1 - 0.028 14.2 0.0 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 EDP44806.1 - 0.03 13.2 0.0 0.062 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDP44806.1 - 0.15 10.5 0.1 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EDP44806.1 - 0.18 10.7 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EDP44806.1 - 0.19 11.7 0.1 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Hexokinase_2 PF03727.11 EDP44807.1 - 1.3e-77 260.3 0.0 2.3e-77 259.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EDP44807.1 - 4.8e-66 221.9 0.1 7.3e-66 221.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Tox-PL-2 PF15643.1 EDP44807.1 - 0.063 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Papain fold toxin 2 FGGY_N PF00370.16 EDP44807.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain GDC-P PF02347.11 EDP44808.1 - 9.7e-181 601.1 0.0 7.8e-170 565.1 0.0 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EDP44808.1 - 1.4e-05 24.3 0.1 3.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDP44808.1 - 0.0014 17.4 0.6 0.0059 15.3 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Pkinase PF00069.20 EDP44809.1 - 2.6e-62 210.3 0.1 1.6e-41 142.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44809.1 - 2.2e-26 92.5 0.0 8.3e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDP44809.1 - 1.1e-05 24.5 1.1 0.00017 20.6 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EDP44809.1 - 0.00032 20.5 0.4 0.026 14.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDP44809.1 - 0.01 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EDP44809.1 - 0.018 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EDP44809.1 - 0.042 12.6 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.19 EDP44809.1 - 0.07 13.6 0.2 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain tRNA_m1G_MT PF01746.16 EDP44810.1 - 4.6e-22 78.5 0.0 5.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF411 PF04214.8 EDP44810.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF PCI PF01399.22 EDP44811.1 - 7.1e-05 23.0 0.0 0.00056 20.1 0.0 2.4 1 1 0 1 1 1 1 PCI domain Cwf_Cwc_15 PF04889.7 EDP44812.1 - 4.3e-45 154.3 29.6 5.3e-45 154.0 20.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EDP44812.1 - 0.099 10.6 15.9 0.1 10.6 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Takusan PF04822.8 EDP44812.1 - 0.2 11.4 8.3 0.18 11.5 2.5 2.9 3 0 0 3 3 3 0 Takusan GED PF02212.13 EDP44812.1 - 1.4 8.9 6.9 1.1 9.2 3.5 1.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain Astro_capsid PF03115.9 EDP44812.1 - 4 5.5 11.0 4.5 5.4 7.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ATP_bind_1 PF03029.12 EDP44813.1 - 1.4e-80 270.2 0.1 1.7e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDP44813.1 - 4.9e-08 33.8 0.0 1.3e-07 32.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EDP44813.1 - 7.3e-05 22.2 0.0 0.00019 20.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EDP44813.1 - 0.00015 21.8 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDP44813.1 - 0.0005 20.3 0.4 0.0015 18.8 0.0 2.0 2 2 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDP44813.1 - 0.0007 19.2 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDP44813.1 - 0.0011 18.3 0.1 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArgK PF03308.11 EDP44813.1 - 0.0016 17.2 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein Gtr1_RagA PF04670.7 EDP44813.1 - 0.0027 16.8 0.0 0.051 12.7 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MobB PF03205.9 EDP44813.1 - 0.003 17.2 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EDP44813.1 - 0.0041 16.6 0.0 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EDP44813.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EDP44813.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDP44813.1 - 0.005 17.0 0.0 0.093 12.9 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EDP44813.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 EDP44813.1 - 0.0061 16.8 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EDP44813.1 - 0.0078 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDP44813.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP44813.1 - 0.009 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDP44813.1 - 0.0092 15.9 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EDP44813.1 - 0.011 15.1 0.4 0.06 12.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EDP44813.1 - 0.014 14.8 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain T2SE PF00437.15 EDP44813.1 - 0.019 13.9 0.0 0.033 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EDP44813.1 - 0.031 13.9 0.0 0.065 12.9 0.0 1.5 2 0 0 2 2 1 0 NTPase NACHT PF05729.7 EDP44813.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 EDP44813.1 - 0.05 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EDP44813.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EDP44813.1 - 0.072 12.5 0.1 2.9 7.2 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EDP44813.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3605 PF12239.3 EDP44813.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) DUF258 PF03193.11 EDP44813.1 - 0.15 11.2 0.0 0.56 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ALAD PF00490.16 EDP44814.1 - 5.9e-64 216.0 0.0 6.5e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 EDP44815.1 - 4e-66 222.8 0.0 5.7e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44815.1 - 8.7e-30 103.6 0.2 1.2e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP44815.1 - 9.3e-09 34.6 0.0 1.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP44815.1 - 0.018 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP44815.1 - 0.02 14.6 0.0 0.53 9.9 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family IF4E PF01652.13 EDP44816.1 - 2.5e-45 153.9 0.1 3.5e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Shisa PF13908.1 EDP44817.1 - 0.049 13.8 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Exo70 PF03081.10 EDP44818.1 - 4.7e-07 28.9 0.0 5.5e-07 28.7 0.0 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Exo70 PF03081.10 EDP44819.1 - 9.1e-08 31.2 0.2 6e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit FANCI_S2 PF14676.1 EDP44819.1 - 0.056 13.3 1.5 0.076 12.9 0.2 1.8 2 0 0 2 2 2 0 FANCI solenoid 2 Y_phosphatase PF00102.22 EDP44820.1 - 1.8e-37 128.9 0.0 2.7e-37 128.3 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EDP44820.1 - 0.00018 21.1 0.0 0.00053 19.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EDP44820.1 - 0.085 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Peptidase_M28 PF04389.12 EDP44820.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Meth_synt_2 PF01717.13 EDP44823.1 - 8.8e-144 478.4 0.0 1.4e-137 458.0 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDP44823.1 - 1e-120 402.7 0.0 7.1e-108 360.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 EDP44823.1 - 4.2e-05 22.8 1.0 9.8e-05 21.6 0.7 1.7 1 0 0 1 1 1 1 Short C-terminal domain TMP-TENI PF02581.12 EDP44823.1 - 0.11 11.5 0.0 0.44 9.6 0.0 2.1 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI Methyltransf_7 PF03492.10 EDP44824.1 - 0.0068 15.2 1.5 1.5 7.4 0.0 2.7 1 1 2 3 3 3 2 SAM dependent carboxyl methyltransferase FYVE PF01363.16 EDP44825.1 - 6e-16 58.0 7.9 1.2e-15 57.0 5.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 EDP44825.1 - 0.00066 19.1 0.8 0.0022 17.5 0.3 2.0 2 0 0 2 2 2 1 Rabenosyn Rab binding domain DPBB_1 PF03330.13 EDP44826.1 - 4.8e-06 26.4 0.1 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDP44826.1 - 0.0031 17.1 0.2 0.0042 16.7 0.2 1.3 1 1 0 1 1 1 1 Barwin family ETF_QO PF05187.8 EDP44827.1 - 9.2e-40 135.0 0.0 1.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EDP44827.1 - 2.7e-07 29.8 0.6 0.00023 20.1 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDP44827.1 - 7.6e-07 28.3 2.1 0.00019 20.4 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDP44827.1 - 1.6e-06 28.0 0.2 5.2e-06 26.3 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDP44827.1 - 5.1e-05 22.4 0.4 0.00012 21.2 0.2 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EDP44827.1 - 0.00018 20.1 1.3 0.00027 19.5 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EDP44827.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDP44827.1 - 0.00045 19.2 0.3 0.00071 18.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EDP44827.1 - 0.001 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDP44827.1 - 0.002 18.2 0.2 0.0035 17.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDP44827.1 - 0.002 17.2 0.5 0.0031 16.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EDP44827.1 - 0.0024 17.6 0.2 0.0059 16.3 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 EDP44827.1 - 0.015 15.6 2.7 0.034 14.5 1.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 EDP44827.1 - 0.027 14.3 0.6 0.059 13.2 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDP44827.1 - 0.037 13.9 0.9 0.11 12.4 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Trp_halogenase PF04820.9 EDP44827.1 - 0.04 12.5 0.8 0.098 11.2 0.6 1.6 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_10 PF13237.1 EDP44827.1 - 0.11 12.2 2.4 0.21 11.4 1.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.1 EDP44827.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EDP44827.1 - 0.26 10.1 0.7 0.41 9.4 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_6 PF12837.2 EDP44827.1 - 3.4 7.6 5.7 1 9.3 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain B3_4 PF03483.12 EDP44828.1 - 1.7e-10 40.6 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain G-patch PF01585.18 EDP44830.1 - 1.8e-11 43.6 1.7 4.3e-11 42.4 1.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDP44830.1 - 0.00069 19.4 1.4 0.0021 17.8 1.0 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site BMP2K_C PF15282.1 EDP44830.1 - 0.0095 16.1 1.4 0.012 15.8 0.9 1.3 1 0 0 1 1 1 1 BMP-2-inducible protein kinase C-terminus polyprenyl_synt PF00348.12 EDP44831.1 - 4.8e-73 245.2 0.0 6.1e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CN_hydrolase PF00795.17 EDP44832.1 - 5.1e-24 84.6 0.0 1.8e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Peptidase_S24 PF00717.18 EDP44833.1 - 3.6e-05 23.3 0.2 0.0043 16.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.4 EDP44833.1 - 0.031 13.7 0.0 13 5.2 0.0 3.3 2 1 1 3 3 3 0 Signal peptidase, peptidase S26 Metallophos PF00149.23 EDP44834.1 - 0.0002 20.8 2.6 0.0012 18.3 1.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ICL PF00463.16 EDP44835.1 - 6.3e-193 641.7 0.0 7.2e-193 641.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDP44835.1 - 9.9e-09 34.7 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RNA_pol_Rpc4 PF05132.9 EDP44836.1 - 2.9e-28 98.4 0.0 9.3e-28 96.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF2408 PF10303.4 EDP44837.1 - 2.5e-45 153.8 0.1 5.9e-33 113.8 0.0 4.2 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) DUF3782 PF12644.2 EDP44837.1 - 0.083 12.6 0.9 4.6 7.1 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3782) IncA PF04156.9 EDP44837.1 - 0.12 11.9 8.4 0.076 12.5 0.8 3.2 3 0 0 3 3 3 0 IncA protein APG6 PF04111.7 EDP44837.1 - 0.13 11.3 5.1 0.05 12.6 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 EDP44837.1 - 0.6 9.8 5.4 6.8 6.4 0.6 3.9 4 1 1 5 5 5 0 Laminin Domain II Fib_alpha PF08702.5 EDP44837.1 - 1.4 9.0 5.3 2.5 8.2 0.3 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CENP-H PF05837.7 EDP44837.1 - 4.8 7.4 8.6 0.22 11.7 0.4 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) CHASE3 PF05227.8 EDP44837.1 - 9.2 5.9 10.7 1.7 8.3 1.6 3.3 3 1 0 3 3 3 0 CHASE3 domain Bax1-I PF01027.15 EDP44838.1 - 1.3e-33 116.3 8.8 2e-33 115.7 6.1 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pex14_N PF04695.8 EDP44838.1 - 0.14 12.1 0.4 0.3 11.1 0.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Profilin PF00235.14 EDP44839.1 - 8.8e-40 135.5 0.0 9.8e-40 135.4 0.0 1.0 1 0 0 1 1 1 1 Profilin TIM PF00121.13 EDP44840.1 - 9e-94 313.0 0.1 1e-93 312.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3802 PF12290.3 EDP44840.1 - 0.025 14.8 0.1 6.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) CutC PF03932.9 EDP44840.1 - 0.028 13.6 0.1 0.1 11.8 0.0 1.7 1 1 1 2 2 2 0 CutC family RNA_pol_Rpa2_4 PF06883.7 EDP44840.1 - 0.13 12.2 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain Spo12 PF05032.7 EDP44841.1 - 3.9e-07 29.5 1.0 7.6e-07 28.6 0.7 1.5 1 0 0 1 1 1 1 Spo12 family MBD PF01429.14 EDP44841.1 - 0.027 13.9 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyl-CpG binding domain AICARFT_IMPCHas PF01808.13 EDP44842.1 - 3e-107 358.3 0.0 4e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EDP44842.1 - 7.5e-20 70.6 0.0 1.4e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Mon1 PF03164.9 EDP44843.1 - 3.6e-36 124.6 0.1 4.8e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Methyltransf_10 PF05971.7 EDP44844.1 - 2e-21 76.4 0.0 2.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) CoA_transf_3 PF02515.12 EDP44844.1 - 0.00022 20.5 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Methyltransf_18 PF12847.2 EDP44844.1 - 0.0047 17.4 0.0 0.0072 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP44844.1 - 0.09 13.2 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Radical_SAM PF04055.16 EDP44845.1 - 1.2e-10 41.7 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily ATP_bind_1 PF03029.12 EDP44846.1 - 2.6e-72 243.2 0.6 1.8e-65 220.8 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein CbiA PF01656.18 EDP44846.1 - 7e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EDP44846.1 - 7.4e-06 25.5 0.0 2.7e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EDP44846.1 - 2.2e-05 23.9 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EDP44846.1 - 5.3e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EDP44846.1 - 6.3e-05 22.5 0.0 0.00057 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EDP44846.1 - 9.9e-05 22.4 0.1 0.00054 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EDP44846.1 - 0.00021 21.2 0.2 0.00051 19.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP44846.1 - 0.00023 21.9 0.1 0.0013 19.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDP44846.1 - 0.00044 19.7 0.2 0.0057 16.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 EDP44846.1 - 0.00045 19.9 0.0 0.00082 19.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EDP44846.1 - 0.0005 20.2 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDP44846.1 - 0.00069 19.0 2.6 0.017 14.4 1.8 2.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EDP44846.1 - 0.00092 18.5 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EDP44846.1 - 0.0017 18.8 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EDP44846.1 - 0.0049 15.6 0.1 0.02 13.6 0.0 1.9 2 0 0 2 2 2 1 ArgK protein AAA_24 PF13479.1 EDP44846.1 - 0.0059 16.2 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDP44846.1 - 0.0069 15.8 0.2 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 EDP44846.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDP44846.1 - 0.014 14.6 0.0 0.067 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EDP44846.1 - 0.015 15.1 0.7 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 EDP44846.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EDP44846.1 - 0.019 15.1 0.0 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EDP44846.1 - 0.019 14.6 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EDP44846.1 - 0.022 14.2 0.0 0.056 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EDP44846.1 - 0.023 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDP44846.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRPRB PF09439.5 EDP44846.1 - 0.053 12.7 0.5 1.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 EDP44846.1 - 0.072 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.15 EDP44846.1 - 0.11 11.1 0.0 10 4.6 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit KTI12 PF08433.5 EDP44846.1 - 0.12 11.5 0.1 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EDP44846.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EDP44846.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MipZ PF09140.6 EDP44846.1 - 0.18 10.8 0.9 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ ADH_N PF08240.7 EDP44847.1 - 1.1e-24 86.3 3.2 2.7e-24 85.0 1.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP44847.1 - 4.4e-10 39.1 0.0 8.9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDP44847.1 - 0.00016 20.8 0.1 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EDP44847.1 - 0.00023 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EDP44847.1 - 0.00066 19.5 0.5 0.0012 18.6 0.3 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EDP44847.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EDP44847.1 - 0.0015 18.1 0.1 0.0047 16.5 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EDP44847.1 - 0.0081 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EDP44847.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EDP44847.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase DUF202 PF02656.10 EDP44848.1 - 3e-14 52.9 0.2 3e-14 52.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DctQ PF04290.7 EDP44848.1 - 0.32 10.7 6.0 0.23 11.2 1.5 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component COX17 PF05051.8 EDP44849.1 - 5.2e-18 64.7 4.8 7.4e-18 64.3 3.4 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 EDP44849.1 - 0.0039 17.0 1.5 0.0055 16.5 1.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Ribosomal_60s PF00428.14 EDP44850.1 - 7.3e-26 90.4 10.8 8.8e-26 90.1 7.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Trehalase PF01204.13 EDP44851.1 - 7.2e-156 519.8 0.1 9.1e-156 519.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EDP44851.1 - 6.6e-12 44.5 2.2 1.1e-11 43.8 1.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ThiF PF00899.16 EDP44852.1 - 4.8e-29 100.9 0.0 9.6e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EDP44852.1 - 2.3e-05 24.5 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF2318 PF10080.4 EDP44852.1 - 0.021 14.6 0.3 0.043 13.5 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) ApbA PF02558.11 EDP44852.1 - 0.18 11.2 0.1 0.44 9.9 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ALS_ss_C PF10369.4 EDP44853.1 - 6.3e-20 70.6 0.0 4e-17 61.6 0.0 2.6 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 EDP44853.1 - 1.3e-10 40.5 0.1 2.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EDP44853.1 - 4.3e-07 29.6 0.0 8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EDP44853.1 - 0.053 13.2 0.8 0.16 11.7 0.1 2.1 2 1 0 2 2 2 0 ACT domain ACT_7 PF13840.1 EDP44853.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain ERO1 PF04137.10 EDP44854.1 - 1.4e-119 399.3 0.0 2.9e-119 398.2 0.0 1.5 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DASH_Dad4 PF08650.5 EDP44857.1 - 7.8e-21 73.7 6.2 9.4e-21 73.5 4.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EDP44857.1 - 0.00038 20.0 0.9 0.00056 19.5 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 Duffy_binding PF05424.6 EDP44857.1 - 0.067 13.0 0.1 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Duffy binding domain GM_CSF PF01109.12 EDP44857.1 - 0.11 12.4 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Ribosomal_S21 PF01165.15 EDP44858.1 - 4e-11 42.1 8.1 6.9e-11 41.4 5.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Rot1 PF10681.4 EDP44859.1 - 1.4e-47 161.8 1.4 1.7e-47 161.5 1.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EDP44859.1 - 0.014 16.0 0.3 0.024 15.2 0.2 1.5 1 1 0 1 1 1 0 Lipocalin-like domain DUF619 PF04768.8 EDP44860.1 - 2e-34 118.4 0.0 4.3e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) MBOAT PF03062.14 EDP44861.1 - 2.5e-05 23.5 0.6 2.5e-05 23.5 0.4 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Clat_adaptor_s PF01217.15 EDP44862.1 - 4.7e-55 185.2 1.4 5.6e-55 184.9 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Band_3_cyto PF07565.8 EDP44862.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pcc1 PF09341.5 EDP44863.1 - 2.5e-15 56.2 0.1 3e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PIF1 PF05970.9 EDP44864.1 - 1e-60 205.6 0.1 6e-48 163.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EDP44864.1 - 5.1e-18 65.3 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDP44864.1 - 2.6e-06 27.5 0.0 1.1e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EDP44864.1 - 2.4e-05 23.9 0.0 0.028 13.9 0.0 2.6 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EDP44864.1 - 4.6e-05 21.3 0.6 0.0061 14.3 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 EDP44864.1 - 0.00032 20.3 0.1 0.00082 19.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDP44864.1 - 0.00032 20.7 0.1 0.0031 17.6 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EDP44864.1 - 0.0016 18.1 0.1 0.021 14.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EDP44864.1 - 0.0034 16.5 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 EDP44864.1 - 0.0049 16.1 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 EDP44864.1 - 0.0096 16.1 0.0 0.031 14.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP44864.1 - 0.013 15.5 0.1 0.049 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain AAA_14 PF13173.1 EDP44864.1 - 0.014 15.3 0.0 0.074 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDP44864.1 - 0.014 15.1 0.1 0.087 12.5 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EDP44864.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EDP44864.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EDP44864.1 - 0.016 14.8 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zot PF05707.7 EDP44864.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 EDP44864.1 - 0.036 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 EDP44864.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EDP44864.1 - 0.13 12.4 0.2 0.41 10.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.10 EDP44864.1 - 0.13 11.9 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 EDP44864.1 - 0.15 10.9 0.1 0.49 9.3 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IF-2B PF01008.12 EDP44865.1 - 1.1e-52 178.7 0.0 3.4e-52 177.2 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2013 PF09431.5 EDP44866.1 - 8.9e-34 116.2 0.3 1.4e-33 115.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) ORC4_C PF14629.1 EDP44867.1 - 1.3e-37 129.1 0.0 3.6e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EDP44867.1 - 2.4e-21 76.5 8.7 1e-20 74.5 2.7 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDP44867.1 - 4.3e-06 26.8 0.0 0.0019 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EDP44867.1 - 2.6e-05 24.4 0.0 0.047 13.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDP44867.1 - 3.4e-05 23.5 0.4 0.0029 17.2 0.1 3.1 2 1 0 2 2 2 1 NACHT domain ORC3_N PF07034.6 EDP44867.1 - 0.0013 17.7 0.4 0.0025 16.8 0.1 1.6 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ABC_tran PF00005.22 EDP44867.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EDP44867.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CLASP_N PF12348.3 EDP44867.1 - 0.017 14.4 0.4 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 CLASP N terminal DUF258 PF03193.11 EDP44867.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EDP44867.1 - 0.023 14.3 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDP44867.1 - 0.031 14.4 0.0 0.084 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.9 EDP44867.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PAXNEB PF05625.6 EDP44868.1 - 1.3e-33 116.3 0.0 8.5e-27 93.9 0.0 3.3 2 1 0 2 2 2 2 PAXNEB protein AAA PF00004.24 EDP44869.1 - 4.4e-44 149.8 0.0 8.7e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDP44869.1 - 1e-07 32.0 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDP44869.1 - 1.3e-06 28.1 0.0 6.1e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDP44869.1 - 3.1e-06 27.3 0.3 0.0004 20.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP44869.1 - 3.4e-06 27.1 0.1 2.2e-05 24.5 0.0 2.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 EDP44869.1 - 6.5e-05 23.7 0.0 0.00017 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP44869.1 - 9.2e-05 21.5 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDP44869.1 - 0.00011 21.8 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDP44869.1 - 0.00045 19.6 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EDP44869.1 - 0.00091 18.0 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDP44869.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EDP44869.1 - 0.0016 17.6 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EDP44869.1 - 0.0019 17.8 0.0 0.0084 15.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDP44869.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDP44869.1 - 0.0025 16.9 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EDP44869.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDP44869.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDP44869.1 - 0.0081 15.5 0.2 0.097 12.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDP44869.1 - 0.0083 15.3 0.1 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EDP44869.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EDP44869.1 - 0.018 14.4 0.0 0.094 12.1 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EDP44869.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDP44869.1 - 0.025 13.5 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 EDP44869.1 - 0.03 14.2 0.2 0.069 13.0 0.2 1.7 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 EDP44869.1 - 0.034 13.8 0.0 0.61 9.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EDP44869.1 - 0.037 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EDP44869.1 - 0.051 12.4 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EDP44869.1 - 0.057 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EDP44869.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Dus PF01207.12 EDP44870.1 - 1.6e-71 240.7 0.0 3.8e-71 239.4 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-DHHC PF01529.15 EDP44871.1 - 2.1e-39 134.6 0.5 3.1e-39 134.1 0.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EDP44871.1 - 0.16 11.8 7.7 0.31 10.9 5.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon CcdB PF01845.12 EDP44871.1 - 0.21 11.5 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 CcdB protein zinc_ribbon_2 PF13240.1 EDP44871.1 - 2.9 7.4 6.0 5.1 6.7 4.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Nodulin-like PF06813.8 EDP44872.1 - 1.3e-22 80.2 6.3 1.7e-22 79.8 4.3 1.1 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EDP44872.1 - 3.4e-17 62.2 2.8 5.4e-17 61.5 1.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4153 PF13687.1 EDP44872.1 - 0.028 13.9 2.4 0.072 12.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4153) UreF PF01730.11 EDP44873.1 - 2.1e-07 31.1 2.9 4.9e-07 29.9 0.9 2.3 1 1 1 2 2 2 1 UreF zf-ZPR1 PF03367.8 EDP44874.1 - 3e-101 335.3 0.0 1.6e-49 167.2 0.0 3.0 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EDP44874.1 - 0.0021 17.7 2.4 1.3 8.7 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EDP44874.1 - 0.16 11.7 7.5 5.1 7.0 0.6 3.2 2 2 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EDP44874.1 - 0.87 9.5 6.7 4.2 7.3 0.2 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EDP44874.1 - 2.3 7.8 13.5 0.76 9.3 0.8 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EDP44874.1 - 2.4 7.4 10.8 3.8 6.8 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 EDP44874.1 - 2.9 7.9 7.4 6.4 6.9 0.0 3.2 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.8 EDP44874.1 - 3.6 7.3 6.1 25 4.6 1.1 3.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like UPF0160 PF03690.8 EDP44875.1 - 9.2e-120 399.8 0.0 1e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GMC_oxred_N PF00732.14 EDP44876.1 - 5.9e-58 196.3 0.0 9.1e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDP44876.1 - 7.8e-36 123.5 0.0 2e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EDP44876.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EDP44876.1 - 0.00018 20.5 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDP44876.1 - 0.00065 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDP44876.1 - 0.00088 18.2 0.1 0.0017 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDP44876.1 - 0.001 19.0 0.0 0.008 16.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDP44876.1 - 0.0016 18.5 0.0 0.085 12.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP44876.1 - 0.0061 15.0 0.7 0.022 13.2 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EDP44876.1 - 0.016 14.3 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EDP44876.1 - 0.033 13.9 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding RNase_H2_suC PF08615.6 EDP44879.1 - 8.8e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Evr1_Alr PF04777.8 EDP44881.1 - 2e-29 101.3 2.0 4.2e-29 100.2 1.2 1.6 2 0 0 2 2 2 1 Erv1 / Alr family Indigoidine_A PF04227.7 EDP44882.1 - 1e-109 366.3 0.6 1.5e-109 365.7 0.0 1.5 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 EDP44882.1 - 1.8e-17 63.4 0.2 4.2e-17 62.2 0.2 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Abhydrolase_6 PF12697.2 EDP44883.1 - 3.1e-32 112.2 0.0 4.5e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44883.1 - 6.6e-22 78.2 0.1 9.2e-21 74.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDP44883.1 - 4e-15 55.8 0.0 8.1e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDP44883.1 - 2.6e-05 23.7 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EDP44883.1 - 0.00033 20.0 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 EDP44883.1 - 0.0018 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EDP44883.1 - 0.0033 17.0 0.1 0.088 12.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDP44883.1 - 0.0051 16.0 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.8 EDP44883.1 - 0.0069 16.0 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EDP44883.1 - 0.0082 15.6 0.0 0.27 10.6 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_PK PF05891.7 EDP44884.1 - 1.3e-45 155.3 0.0 2.5e-20 72.7 0.0 3.4 2 2 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 EDP44884.1 - 1.4e-05 25.4 0.0 0.0057 17.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP44884.1 - 0.0019 18.7 0.0 0.0031 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP44884.1 - 0.024 15.0 0.0 0.42 11.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain CitG PF01874.11 EDP44884.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Na_H_Exchanger PF00999.16 EDP44885.1 - 1.6e-49 168.4 15.2 2e-49 168.1 10.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EDP44885.1 - 9.6e-06 25.4 0.4 0.0007 19.4 0.0 2.8 2 0 0 2 2 2 1 YrhC-like protein Anoctamin PF04547.7 EDP44886.1 - 3.3e-08 32.6 0.5 4.5e-08 32.1 0.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel bZIP_2 PF07716.10 EDP44886.1 - 0.12 12.1 1.6 0.21 11.4 1.1 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Anoctamin PF04547.7 EDP44887.1 - 7e-76 255.6 3.7 8.6e-76 255.3 2.5 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel UBX PF00789.15 EDP44888.1 - 4.9e-17 61.7 0.0 1.3e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 UBX domain Abhydrolase_5 PF12695.2 EDP44889.1 - 8.6e-05 22.3 0.0 0.0002 21.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDP44889.1 - 0.0053 16.3 0.0 0.0087 15.6 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDP44889.1 - 0.0068 16.3 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44889.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EDP44889.1 - 0.065 12.6 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EDP44889.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDP44889.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Memo PF01875.12 EDP44891.1 - 1.2e-39 135.9 0.0 1.3e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein ResIII PF04851.10 EDP44892.1 - 8.2e-23 81.1 0.2 3.2e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDP44892.1 - 2.5e-18 66.1 0.2 6.2e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP44892.1 - 2e-11 43.6 0.0 4.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 EDP44892.1 - 3.3e-06 26.8 0.0 0.0018 17.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain DUF2075 PF09848.4 EDP44892.1 - 7.8e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EDP44892.1 - 0.00021 20.1 0.0 0.00036 19.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_24 PF13479.1 EDP44892.1 - 0.0026 17.3 0.0 0.081 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDP44892.1 - 0.0031 17.6 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EDP44892.1 - 0.0075 15.7 0.0 0.11 11.9 0.0 2.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.16 EDP44892.1 - 0.0076 15.5 0.2 1.4 8.1 0.2 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EDP44892.1 - 0.011 15.4 0.2 0.036 13.8 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EDP44892.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDP44892.1 - 0.035 13.5 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EDP44892.1 - 0.068 12.9 0.0 0.35 10.6 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Helicase_C_2 PF13307.1 EDP44892.1 - 0.078 12.9 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain DUF1992 PF09350.5 EDP44894.1 - 1.7e-15 56.5 0.3 5.6e-15 54.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Cyt-b5 PF00173.23 EDP44895.1 - 4.1e-10 39.3 0.0 5.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cys_Met_Meta_PP PF01053.15 EDP44896.1 - 1.9e-26 92.2 0.0 2.3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDP44896.1 - 2.9e-05 23.2 0.0 3.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDP44896.1 - 0.004 15.9 0.0 0.0043 15.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDP44897.1 - 2.2e-13 49.2 1.6 3.2e-12 45.4 1.1 2.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Utp12 PF04003.7 EDP44899.1 - 0.068 13.0 0.2 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Dip2/Utp12 Family PPTA PF01239.17 EDP44900.1 - 5.6e-15 53.9 1.0 7.7e-09 34.5 0.0 2.2 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat ApoO PF09769.4 EDP44901.1 - 9.4e-18 64.4 0.1 8.8e-17 61.2 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O TPR_16 PF13432.1 EDP44902.1 - 0.11 13.2 0.2 1.6 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP44902.1 - 0.21 11.4 2.0 11 6.0 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TatD_DNase PF01026.16 EDP44904.1 - 1.6e-38 132.3 0.0 2.1e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF3591 PF12157.3 EDP44905.1 - 3.9e-155 516.7 2.2 6.5e-124 413.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EDP44905.1 - 2.2e-05 24.0 2.4 4.6e-05 23.0 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2525 PF10733.4 EDP44905.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) Med16 PF11635.3 EDP44905.1 - 0.071 11.0 0.2 0.11 10.3 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 ApbA_C PF08546.6 EDP44907.1 - 2.4e-39 134.1 0.0 3.8e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDP44907.1 - 2.9e-23 81.9 0.0 1.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA SMC_N PF02463.14 EDP44908.1 - 7.9e-26 90.6 0.0 1.1e-12 47.6 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDP44908.1 - 1.2e-13 51.8 17.4 1.2e-13 51.8 12.1 4.4 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EDP44908.1 - 3.8e-05 22.9 0.0 7.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EDP44908.1 - 6.7e-05 22.9 0.3 0.0026 17.7 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDP44908.1 - 8.5e-05 22.0 0.1 0.00025 20.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 EDP44908.1 - 0.0032 17.4 0.5 0.02 14.8 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 EDP44908.1 - 0.038 14.2 0.1 0.038 14.2 0.1 5.4 3 2 0 4 4 4 0 ABC transporter HTH_26 PF13443.1 EDP44908.1 - 0.068 13.3 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Abhydrolase_6 PF12697.2 EDP44909.1 - 3.7e-16 59.7 0.4 5e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP44909.1 - 5.2e-16 58.7 0.0 8.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDP44909.1 - 3.9e-08 33.0 0.0 5.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EDP44909.1 - 5.7e-07 29.3 0.0 7.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EDP44909.1 - 2.2e-05 24.1 0.2 0.00016 21.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EDP44909.1 - 7.2e-05 21.4 0.0 0.0078 14.7 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EDP44909.1 - 0.00064 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EDP44909.1 - 0.0018 17.7 0.0 0.0047 16.3 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydro_lipase PF04083.11 EDP44909.1 - 0.0021 17.4 0.1 0.0036 16.6 0.1 1.3 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 EDP44909.1 - 0.0081 15.4 0.0 0.061 12.5 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EDP44909.1 - 0.0088 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal 6PF2K PF01591.13 EDP44910.1 - 6.2e-56 188.9 0.0 8.9e-56 188.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDP44910.1 - 5.4e-15 55.8 0.4 1.3e-14 54.5 0.0 1.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDP44910.1 - 1.5e-10 41.1 0.0 5e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EDP44910.1 - 0.0018 17.5 0.0 0.0037 16.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EDP44910.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 EDP44910.1 - 0.041 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SecA_PP_bind PF01043.15 EDP44910.1 - 0.062 13.6 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain tRNA_lig_kinase PF08303.6 EDP44910.1 - 0.066 13.0 0.1 0.23 11.3 0.0 1.8 1 1 1 2 2 2 0 tRNA ligase kinase domain Zeta_toxin PF06414.7 EDP44910.1 - 0.074 12.1 0.1 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin FRG1 PF06229.7 EDP44911.1 - 4.4e-17 62.1 0.0 1.4e-16 60.5 0.0 1.8 2 1 0 2 2 2 1 FRG1-like family Fascin PF06268.8 EDP44911.1 - 0.057 13.5 0.0 0.33 11.0 0.0 2.1 2 1 0 2 2 2 0 Fascin domain DUF4504 PF14953.1 EDP44912.1 - 8.3e-08 31.8 0.3 9e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) OTCace_N PF02729.16 EDP44913.1 - 1.1e-41 141.7 0.1 1.7e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EDP44913.1 - 1.6e-17 63.8 0.0 1.2e-11 44.7 0.0 2.4 1 1 1 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain GSHPx PF00255.14 EDP44914.1 - 6.1e-36 122.0 0.2 1.7e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 Glutathione peroxidase AhpC-TSA PF00578.16 EDP44914.1 - 0.0063 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDP44914.1 - 0.086 12.3 0.0 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Redoxin DUF1115 PF06544.7 EDP44915.1 - 1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) ydhR PF08803.6 EDP44915.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR NDK PF00334.14 EDP44916.1 - 8.6e-56 187.4 0.0 9.8e-56 187.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EDP44916.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ ABC1 PF03109.11 EDP44917.1 - 6.4e-22 77.7 0.0 5.2e-13 49.0 0.0 2.9 3 1 0 3 3 3 2 ABC1 family DUF4404 PF14357.1 EDP44917.1 - 0.089 13.2 0.3 0.26 11.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF1241 PF06840.6 EDP44917.1 - 0.2 10.8 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Sgf11 PF08209.6 EDP44918.1 - 3e-14 52.0 0.5 5.2e-14 51.2 0.4 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF3275 PF11679.3 EDP44918.1 - 8.5 5.9 8.4 0.45 10.1 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Phage_int_SAM_1 PF02899.12 EDP44919.1 - 0.11 12.6 0.8 0.51 10.5 0.1 2.3 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ABC_tran PF00005.22 EDP44920.1 - 3.1e-53 179.7 0.0 4.1e-30 104.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDP44920.1 - 1.7e-50 171.9 28.8 2.5e-27 95.9 7.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EDP44920.1 - 4.2e-08 33.4 5.7 0.45 10.4 0.0 5.1 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 EDP44920.1 - 7.6e-08 31.8 0.0 0.0013 18.0 0.0 3.4 3 1 1 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDP44920.1 - 1e-05 24.9 0.9 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EDP44920.1 - 0.0002 20.8 0.7 0.032 13.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EDP44920.1 - 0.00053 19.9 0.5 0.17 11.8 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EDP44920.1 - 0.0006 19.8 0.3 0.18 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EDP44920.1 - 0.00065 20.1 0.2 0.49 10.9 0.2 2.8 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EDP44920.1 - 0.0014 17.8 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDP44920.1 - 0.0029 17.9 6.6 0.42 10.8 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EDP44920.1 - 0.007 15.8 0.1 0.68 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_30 PF13604.1 EDP44920.1 - 0.0093 15.5 0.5 4.2 6.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP44920.1 - 0.012 16.3 1.3 6 7.7 0.0 3.7 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 EDP44920.1 - 0.021 14.5 0.0 0.58 9.8 0.0 3.1 4 0 0 4 4 4 0 Archaeal ATPase SbcCD_C PF13558.1 EDP44920.1 - 0.057 13.3 0.1 3.3 7.6 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EDP44920.1 - 0.081 13.0 2.5 9 6.4 0.1 3.8 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.20 EDP44920.1 - 0.085 12.3 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EDP44920.1 - 0.12 12.1 4.9 0.14 11.9 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EDP44920.1 - 0.13 11.9 0.5 21 4.8 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EDP44920.1 - 0.21 11.0 1.2 18 4.7 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EDP44920.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain Zeta_toxin PF06414.7 EDP44920.1 - 0.36 9.9 2.3 6.2 5.8 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin PfkB PF00294.19 EDP44921.1 - 1.9e-64 217.7 1.1 2.2e-64 217.5 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDP44921.1 - 7.2e-07 28.6 0.0 1.7e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PCI PF01399.22 EDP44922.1 - 1.3e-16 60.7 0.0 7e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 PCI domain Paf67 PF10255.4 EDP44922.1 - 0.066 12.0 0.4 0.33 9.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 PCI_Csn8 PF10075.4 EDP44922.1 - 0.086 12.6 0.5 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 Sec5 PF15469.1 EDP44923.1 - 1e-50 172.0 0.0 2e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EDP44923.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Flu_C_NS2 PF03555.9 EDP44923.1 - 0.1 12.5 1.5 4.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Influenza C non-structural protein (NS2) SURF1 PF02104.10 EDP44924.1 - 3.2e-42 144.7 0.0 7.4e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 SURF1 family Complex1_51K PF01512.12 EDP44925.1 - 2.3e-47 160.5 0.0 3.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EDP44925.1 - 1.7e-17 62.3 0.2 3.4e-17 61.3 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EDP44925.1 - 2.3e-08 33.7 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain FA_desaturase PF00487.19 EDP44926.1 - 4.5e-23 81.9 17.3 6e-23 81.5 9.6 2.5 1 1 2 3 3 3 1 Fatty acid desaturase Lipid_DES PF08557.5 EDP44926.1 - 5.8e-17 60.6 0.2 1.3e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) GSH_synth_ATP PF03917.12 EDP44927.1 - 4.3e-103 344.7 0.0 6e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EDP44927.1 - 6.8e-35 119.3 0.0 1.3e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase HR1 PF02185.11 EDP44928.1 - 0.057 13.1 0.3 0.087 12.5 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat TIP49 PF06068.8 EDP44929.1 - 1.2e-176 587.2 1.9 1.4e-176 587.0 1.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EDP44929.1 - 1.9e-10 41.0 0.3 6.9e-08 32.7 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDP44929.1 - 2.8e-07 29.8 1.4 0.00018 20.6 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDP44929.1 - 6.4e-06 25.9 0.6 0.0055 16.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDP44929.1 - 9.4e-06 24.9 2.4 0.00019 20.6 0.6 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EDP44929.1 - 1.2e-05 25.4 0.0 0.11 12.6 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP44929.1 - 5.7e-05 23.1 0.0 0.00023 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 EDP44929.1 - 8e-05 21.6 0.3 0.00014 20.8 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 EDP44929.1 - 0.00089 18.7 0.1 0.65 9.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EDP44929.1 - 0.0018 17.9 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EDP44929.1 - 0.0069 15.5 0.1 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EDP44929.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDP44929.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDP44929.1 - 0.021 14.2 0.2 0.054 12.9 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.1 EDP44929.1 - 0.021 14.3 0.1 0.035 13.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDP44929.1 - 0.046 12.6 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EDP44929.1 - 0.058 14.2 0.0 0.18 12.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain Josephin PF02099.12 EDP44930.1 - 5.7e-44 149.5 0.3 1.1e-43 148.5 0.2 1.5 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EDP44930.1 - 0.0011 18.2 5.1 0.082 12.5 0.8 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif Axin_b-cat_bind PF08833.5 EDP44930.1 - 0.037 13.7 2.2 0.17 11.5 1.5 2.2 1 0 0 1 1 1 0 Axin beta-catenin binding domain DUF4555 PF15093.1 EDP44931.1 - 0.036 12.9 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) AA_permease_2 PF13520.1 EDP44932.1 - 8.9e-37 126.6 23.3 1.2e-36 126.2 16.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDP44932.1 - 1.7e-12 46.4 20.6 2.6e-12 45.8 14.3 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3959 PF13105.1 EDP44932.1 - 0.065 12.5 0.4 0.14 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) EAV_GS PF01309.13 EDP44932.1 - 0.13 11.7 0.2 0.13 11.7 0.1 2.5 3 0 0 3 3 3 0 Equine arteritis virus small envelope glycoprotein C2 PF00168.25 EDP44933.1 - 1.7e-20 72.6 0.0 1.5e-15 56.7 0.0 2.9 3 0 0 3 3 3 2 C2 domain Lgl_C PF08596.5 EDP44934.1 - 0.023 13.1 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EDP44934.1 - 0.027 14.3 0.0 1.5 8.8 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat FRQ PF09421.5 EDP44934.1 - 9.6 3.8 7.5 13 3.3 5.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Lgl_C PF08596.5 EDP44935.1 - 2.2e-07 29.7 0.0 3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Imm43 PF15602.1 EDP44935.1 - 0.072 13.0 0.3 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 43 Synaptobrevin PF00957.16 EDP44935.1 - 0.073 12.6 0.7 0.16 11.5 0.5 1.5 1 0 0 1 1 1 0 Synaptobrevin DUF1308 PF07000.6 EDP44936.1 - 2.4e-21 75.7 0.0 5.8e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) LCCL PF03815.14 EDP44936.1 - 1.8e-18 66.3 0.1 3.4e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 LCCL domain CAAD PF14159.1 EDP44936.1 - 0.28 10.8 5.1 0.11 12.1 1.3 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase AMP-binding PF00501.23 EDP44937.1 - 3.1e-36 124.6 0.1 1.9e-35 122.0 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDP44937.1 - 1e-06 29.5 0.1 9.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 EDP44938.1 - 5.4e-13 49.1 0.2 3.5e-08 33.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDP44938.1 - 5.8e-09 35.3 0.8 0.005 16.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EDP44938.1 - 3.8e-08 33.3 0.3 0.077 13.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP44938.1 - 1.3e-06 28.0 0.1 0.066 13.4 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EDP44938.1 - 1.6e-05 25.2 0.3 0.00035 21.0 0.1 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) FUSC_2 PF13515.1 EDP44939.1 - 3.8e-14 52.7 7.5 8.1e-14 51.6 5.2 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EDP44939.1 - 1.3e-11 43.6 1.7 2.2e-11 42.9 1.2 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF939 PF06081.6 EDP44939.1 - 2.1e-05 24.3 2.1 2.1e-05 24.3 1.4 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) ALMT PF11744.3 EDP44939.1 - 0.00011 21.0 1.9 0.00011 21.0 1.3 1.8 2 0 0 2 2 2 1 Aluminium activated malate transporter NT5C PF06941.7 EDP44939.1 - 0.047 13.1 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF1769 PF08588.5 EDP44940.1 - 4.3e-22 77.7 0.1 9.8e-22 76.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) FNIP PF05725.7 EDP44940.1 - 0.087 12.7 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 FNIP Repeat Cellulase PF00150.13 EDP44941.1 - 2.7e-18 66.1 0.8 3.8e-18 65.6 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RED_N PF07808.8 EDP44941.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region GRASP55_65 PF04495.9 EDP44942.1 - 6.1e-61 204.4 0.0 8.9e-54 181.2 0.0 2.1 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EDP44942.1 - 0.0019 18.0 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EDP44942.1 - 0.14 12.3 0.0 6.2 7.0 0.0 2.4 2 1 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) GMC_oxred_N PF00732.14 EDP44943.1 - 2.9e-73 246.6 0.3 4e-73 246.1 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDP44943.1 - 9.3e-34 116.7 0.0 1.8e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EDP44943.1 - 7.6e-08 32.6 0.4 0.0082 16.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDP44943.1 - 2.6e-07 29.8 0.0 0.00017 20.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDP44943.1 - 3.2e-05 22.9 1.7 0.0021 16.9 0.5 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EDP44943.1 - 4.2e-05 23.5 0.1 0.0093 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP44943.1 - 0.00027 19.5 0.6 0.051 12.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EDP44943.1 - 0.00028 20.8 1.1 0.00092 19.1 0.3 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDP44943.1 - 0.00073 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EDP44943.1 - 0.0062 15.6 0.9 0.062 12.3 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EDP44943.1 - 0.054 12.5 0.9 0.36 9.8 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EDP44943.1 - 0.057 13.8 0.6 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDP44943.1 - 0.072 12.8 0.2 0.33 10.6 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EDP44943.1 - 0.087 12.8 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain GMC_oxred_N PF00732.14 EDP44944.1 - 2e-62 211.0 0.0 3e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDP44944.1 - 3.6e-35 121.3 0.0 1.2e-34 119.7 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EDP44944.1 - 7e-06 26.0 0.2 0.0021 17.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDP44944.1 - 9.3e-06 25.5 0.0 9.8e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDP44944.1 - 1.1e-05 24.5 0.0 6.9e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDP44944.1 - 3.3e-05 22.9 0.4 0.0004 19.3 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EDP44944.1 - 0.00014 20.8 0.1 0.00027 19.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EDP44944.1 - 0.00017 21.7 0.0 0.08 12.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDP44944.1 - 0.011 14.1 0.6 0.088 11.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EDP44944.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding RWD PF05773.17 EDP44945.1 - 2.7e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.20 EDP44946.1 - 7.3e-20 71.2 0.6 1.2e-19 70.5 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP44946.1 - 1.4e-12 47.2 1.4 2.6e-12 46.3 0.9 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sec23_helical PF04815.10 EDP44946.1 - 0.029 13.7 0.8 0.092 12.1 0.6 1.9 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Elf1 PF05129.8 EDP44947.1 - 2.1e-27 94.6 0.7 2.3e-27 94.4 0.5 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EDP44947.1 - 0.0043 17.1 0.8 0.0054 16.8 0.6 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-BED PF02892.10 EDP44947.1 - 0.056 13.2 1.6 1.6 8.5 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger Peptidase_U32 PF01136.14 EDP44947.1 - 0.14 11.0 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Peptidase family U32 Zn_Tnp_IS1595 PF12760.2 EDP44947.1 - 0.22 11.3 1.7 0.33 10.8 1.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 EDP44947.1 - 0.63 10.0 3.8 1.3 8.9 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger RabGAP-TBC PF00566.13 EDP44948.1 - 8.2e-50 169.2 0.6 1.2e-49 168.7 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EDP44948.1 - 3.9e-06 26.2 0.0 8.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain FA_hydroxylase PF04116.8 EDP44949.1 - 1.1e-09 38.6 12.8 1.6e-09 38.1 8.9 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Aa_trans PF01490.13 EDP44950.1 - 3.5e-79 266.1 36.8 4.3e-79 265.8 25.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein LMF1 PF06762.9 EDP44950.1 - 0.12 11.1 5.2 0.16 10.7 2.9 1.6 1 1 0 1 1 1 0 Lipase maturation factor ALMT PF11744.3 EDP44951.1 - 2.5 6.6 5.9 4.6 5.7 0.3 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter Mtr2 PF10429.4 EDP44952.1 - 3.3e-07 30.2 0.0 6.1e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 EDP44952.1 - 6.3e-07 29.7 0.0 1.9e-05 24.9 0.0 2.7 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain DUF383 PF04063.9 EDP44953.1 - 3.5e-57 193.0 0.1 2.8e-56 190.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EDP44953.1 - 7.8e-19 66.9 1.1 1.8e-18 65.8 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 EDP44953.1 - 0.0063 16.7 6.8 5.6 7.3 0.0 4.6 3 3 1 4 4 4 2 HEAT repeats PAPA-1 PF04795.7 EDP44953.1 - 7.8 7.2 6.9 11 6.7 2.3 2.2 2 0 0 2 2 2 0 PAPA-1-like conserved region Ribosomal_L34 PF00468.12 EDP44954.1 - 7e-17 60.8 7.8 1e-16 60.2 5.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Ank_2 PF12796.2 EDP44956.1 - 1.1e-43 147.5 3.0 8.6e-15 54.8 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDP44956.1 - 2.2e-33 112.4 18.4 9.6e-12 44.0 0.1 6.7 7 0 0 7 7 7 4 Ankyrin repeat zf-DHHC PF01529.15 EDP44956.1 - 8.5e-31 106.6 5.5 8.5e-31 106.6 3.8 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EDP44956.1 - 6.2e-29 99.3 7.0 8.2e-09 35.4 0.1 5.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDP44956.1 - 1.9e-24 85.5 4.8 2.6e-09 37.3 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDP44956.1 - 3.2e-22 76.3 7.1 1.7e-07 30.7 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Biotin_lipoyl PF00364.17 EDP44957.1 - 2e-20 72.1 0.3 3.9e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDP44957.1 - 7.6e-08 31.8 0.0 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EDP44957.1 - 0.0044 16.6 0.2 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like Plasmid_stab_B PF10784.4 EDP44957.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Plasmid stability protein QRPTase_N PF02749.11 EDP44957.1 - 0.14 11.9 0.1 0.89 9.4 0.0 2.2 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3446 PF11928.3 EDP44957.1 - 3.1 8.0 13.4 0.18 12.0 4.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 EDP44957.1 - 4.4 6.7 18.4 3.3 7.1 7.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Diphthamide_syn PF01866.12 EDP44958.1 - 6.6e-62 209.5 0.3 2.3e-31 109.1 0.2 3.0 1 1 1 2 2 2 2 Putative diphthamide synthesis protein COQ7 PF03232.8 EDP44960.1 - 2.4e-36 124.7 0.1 3.3e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EDP44960.1 - 0.0049 17.2 0.1 0.0092 16.3 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin EAP30 PF04157.11 EDP44961.1 - 3.3e-25 88.5 0.0 4e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family IF2_N PF04760.10 EDP44961.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mito_carr PF00153.22 EDP44962.1 - 1e-16 60.4 5.9 5.2e-09 35.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dak1 PF02733.12 EDP44963.1 - 2.8e-107 358.0 0.6 4.3e-107 357.4 0.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EDP44963.1 - 9.9e-49 165.3 1.2 9.9e-49 165.3 0.9 1.7 2 0 0 2 2 2 1 DAK2 domain Glyco_hydro_3_C PF01915.17 EDP44963.1 - 0.042 13.3 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Flu_M1_C PF08289.6 EDP44963.1 - 0.1 12.6 0.0 0.45 10.5 0.0 2.1 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Pep3_Vps18 PF05131.9 EDP44964.1 - 2.7e-24 85.2 0.0 1.7e-23 82.6 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family zf-RING_2 PF13639.1 EDP44964.1 - 0.0024 17.6 7.4 0.0035 17.1 1.0 3.4 3 0 0 3 3 3 1 Ring finger domain Clathrin PF00637.15 EDP44964.1 - 0.0035 16.9 0.5 0.13 11.8 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.1 EDP44964.1 - 0.0054 16.4 0.4 0.0054 16.4 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDP44964.1 - 0.01 15.4 2.4 0.13 11.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDP44964.1 - 0.011 15.8 1.1 0.033 14.2 0.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger TPR_11 PF13414.1 EDP44964.1 - 0.014 14.9 0.5 0.78 9.4 0.0 2.7 2 0 0 2 2 2 0 TPR repeat zf-Apc11 PF12861.2 EDP44964.1 - 0.017 14.9 0.3 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 EDP44964.1 - 0.02 15.0 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 BicD PF09730.4 EDP44964.1 - 0.036 12.4 0.8 0.06 11.6 0.5 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF2175 PF09943.4 EDP44964.1 - 0.05 13.6 0.0 0.21 11.6 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) FlaC_arch PF05377.6 EDP44964.1 - 0.2 11.5 0.4 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-C3HC4 PF00097.20 EDP44964.1 - 0.2 11.3 3.1 0.15 11.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP44964.1 - 0.26 11.3 3.4 0.53 10.3 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EDP44964.1 - 3.5 7.7 6.3 0.63 10.0 0.2 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.27 EDP44965.1 - 1.7e-20 72.0 1.1 0.0021 17.8 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 EDP44965.1 - 5.6e-05 22.9 0.0 5.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EDP44965.1 - 0.29 10.8 0.1 0.65 9.6 0.0 1.6 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Ssl1 PF04056.9 EDP44966.1 - 1.7e-61 207.1 0.0 2.4e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EDP44966.1 - 8.1e-16 57.7 8.0 8.1e-16 57.7 5.5 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EDP44966.1 - 2.4e-05 24.5 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.11 EDP44966.1 - 0.02 14.5 0.8 0.02 14.5 0.5 4.2 5 0 0 5 5 5 0 HIT zinc finger Ribosomal_S27 PF01599.14 EDP44966.1 - 0.036 13.8 3.3 0.53 10.1 0.1 2.9 2 1 0 2 2 2 0 Ribosomal protein S27a DZR PF12773.2 EDP44966.1 - 0.07 12.9 20.9 0.79 9.5 2.4 3.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EDP44966.1 - 5.2 6.8 23.2 0.56 9.9 2.3 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Tnp_zf-ribbon_2 PF13842.1 EDP44966.1 - 8 6.9 18.6 0.4 11.1 2.5 2.9 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF1212 PF06738.7 EDP44967.1 - 5e-40 137.0 2.2 5.5e-40 136.9 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EDP44967.1 - 6.2e-11 42.3 17.9 1.4e-09 38.0 0.1 3.7 4 0 0 4 4 4 3 Protein of unknown function (DUF3815) Rnk_N PF14760.1 EDP44967.1 - 0.12 12.5 1.0 0.28 11.3 0.7 1.6 1 0 0 1 1 1 0 Rnk N-terminus zf-CHCC PF10276.4 EDP44968.1 - 4e-17 61.7 1.3 7.3e-17 60.9 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EDP44968.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb zf-C2HC_2 PF13913.1 EDP44968.1 - 0.51 10.0 2.8 13 5.5 1.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Tic20 PF09685.5 EDP44969.1 - 0.072 13.0 2.1 0.11 12.4 1.5 1.3 1 0 0 1 1 1 0 Tic20-like protein Ribophorin_I PF04597.9 EDP44970.1 - 2.1e-93 313.1 0.0 2.4e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I RRM_1 PF00076.17 EDP44971.1 - 1.7e-17 62.7 0.0 2.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP44971.1 - 8.5e-13 48.0 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP44971.1 - 1.6e-07 31.0 0.1 4.8e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.9 EDP44971.1 - 0.098 12.2 3.3 0.14 11.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OPA3 PF07047.7 EDP44972.1 - 1.2e-32 112.4 0.4 2e-32 111.7 0.3 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) TetR_C_6 PF13977.1 EDP44972.1 - 0.086 12.8 0.8 0.22 11.5 0.5 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor Aminotran_5 PF00266.14 EDP44973.1 - 7.3e-87 291.5 0.0 1.8e-86 290.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDP44973.1 - 9.7e-05 21.6 0.2 0.00024 20.3 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase EB1 PF03271.12 EDP44974.1 - 2.6e-13 49.7 0.0 5.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif DUF3138 PF11336.3 EDP44974.1 - 0.028 12.6 0.5 0.038 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Suppressor_APC PF11414.3 EDP44974.1 - 0.14 11.9 0.3 0.39 10.5 0.2 1.8 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF566 PF04484.7 EDP44974.1 - 2.1 7.7 6.4 2.9 7.3 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) WD40 PF00400.27 EDP44975.1 - 4.9e-39 130.8 7.9 2.5e-10 39.8 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EDP44975.1 - 0.0055 16.4 0.0 9.6 5.8 0.0 3.5 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDP44975.1 - 0.11 10.2 0.0 2.8 5.6 0.0 2.7 3 1 0 3 3 3 0 IKI3 family MIS13 PF08202.6 EDP44976.1 - 9.2e-20 70.8 7.8 3.1e-19 69.1 0.7 2.4 2 0 0 2 2 2 2 Mis12-Mtw1 protein family DUF4404 PF14357.1 EDP44976.1 - 1.1 9.7 8.3 16 6.0 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) HA2 PF04408.18 EDP44977.1 - 1.7e-16 60.1 0.2 8.5e-16 57.8 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP44977.1 - 5e-12 45.5 0.1 1.3e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDP44977.1 - 2.3e-08 33.8 0.0 6.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold dsrm PF00035.20 EDP44977.1 - 3.4e-08 33.9 0.1 0.0015 19.0 0.0 3.0 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 EDP44977.1 - 9e-06 25.2 0.2 4.2e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase HrpF PF06266.7 EDP44977.1 - 0.028 14.5 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 HrpF protein ApoC-I PF04691.7 EDP44977.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) ATE_C PF04377.10 EDP44978.1 - 1.4e-28 99.5 0.2 2.5e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EDP44978.1 - 2.6e-23 81.6 3.8 2.6e-23 81.6 2.6 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus LRR_6 PF13516.1 EDP44979.1 - 2.2e-09 36.4 1.1 0.0025 17.7 0.0 6.0 6 1 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 EDP44979.1 - 6e-07 28.9 0.2 0.21 11.2 0.0 3.8 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EDP44979.1 - 0.005 16.8 5.0 20 5.9 0.0 6.1 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 EDP44979.1 - 0.8 9.9 7.0 26 5.3 0.0 5.6 5 2 1 6 6 6 0 Leucine Rich Repeat WD40 PF00400.27 EDP44980.1 - 3.2e-19 68.0 6.3 0.00011 21.8 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EDP44980.1 - 1.7e-11 44.4 0.0 3.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EDP44980.1 - 0.12 12.0 0.2 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD synthetase zf-rbx1 PF12678.2 EDP44981.1 - 4e-34 116.5 14.4 5.5e-34 116.1 10.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDP44981.1 - 1.1e-17 63.6 11.7 1.6e-17 63.1 8.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EDP44981.1 - 7.9e-07 28.8 14.6 1.7e-06 27.7 8.2 2.4 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDP44981.1 - 0.00058 19.4 9.7 0.093 12.4 6.2 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDP44981.1 - 0.00063 19.3 12.0 0.012 15.2 8.3 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP44981.1 - 0.006 16.5 11.6 0.23 11.5 8.0 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP44981.1 - 0.47 10.2 10.6 3.6 7.3 7.4 2.4 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 EDP44981.1 - 0.74 9.8 14.0 0.08 12.9 5.8 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EDP44981.1 - 1.2 8.9 6.1 19 5.0 4.3 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EDP44981.1 - 2 8.4 12.5 4.4 7.3 8.6 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDP44981.1 - 2.1 8.5 13.3 1.2 9.2 1.4 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_6 PF14835.1 EDP44981.1 - 2.4 8.0 7.0 0.14 11.9 0.5 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein OB_NTP_bind PF07717.11 EDP44982.1 - 2.6e-27 94.9 0.1 6.8e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDP44982.1 - 9.6e-26 89.7 0.6 5.1e-25 87.4 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP44982.1 - 2.1e-13 49.9 0.0 4.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDP44982.1 - 5.7e-05 23.2 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EDP44982.1 - 7.6e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDP44982.1 - 0.00027 19.9 0.0 0.00064 18.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EDP44982.1 - 0.0062 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EDP44982.1 - 0.0093 16.2 0.2 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 EDP44982.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDP44982.1 - 0.017 14.5 0.7 0.082 12.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EDP44982.1 - 0.019 14.6 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DAP3 PF10236.4 EDP44982.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.7 EDP44982.1 - 0.047 12.7 0.3 0.2 10.7 0.2 2.0 1 1 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EDP44982.1 - 0.087 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC G-alpha PF00503.15 EDP44982.1 - 0.1 11.2 0.1 0.24 10.0 0.1 1.5 2 0 0 2 2 2 0 G-protein alpha subunit zf-HC5HC2H_2 PF13832.1 EDP44983.1 - 3.6e-33 113.8 7.7 3.6e-33 113.8 5.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDP44983.1 - 3.6e-25 87.9 6.4 3.6e-25 87.9 4.4 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 EDP44983.1 - 8.9e-24 83.2 0.1 1.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.4 EDP44983.1 - 1.2e-21 77.6 3.2 2.9e-21 76.3 2.2 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EDP44983.1 - 2.6e-15 55.4 1.7 2.6e-15 55.4 1.2 3.0 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EDP44983.1 - 4.3e-08 32.7 8.9 4.3e-08 32.7 6.2 3.1 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.17 EDP44983.1 - 0.0023 17.6 0.7 0.0023 17.6 0.5 3.2 3 1 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EDP44983.1 - 4.2 7.1 19.4 1.2 8.8 3.1 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AAA PF00004.24 EDP44984.1 - 3.4e-48 163.1 0.0 5.4e-42 143.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP44984.1 - 3.4e-08 33.6 0.1 3.9e-05 23.7 0.0 3.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDP44984.1 - 6.5e-08 32.7 0.1 0.003 17.7 0.0 4.6 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EDP44984.1 - 1.8e-07 30.7 0.0 0.00041 19.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EDP44984.1 - 4.3e-06 26.8 0.1 0.029 14.3 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_2 PF07724.9 EDP44984.1 - 6e-06 26.2 0.0 4.8e-05 23.3 0.0 2.5 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDP44984.1 - 3.4e-05 23.6 0.0 0.0069 16.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDP44984.1 - 0.00054 19.8 1.0 0.021 14.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDP44984.1 - 0.00066 19.3 0.2 0.004 16.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EDP44984.1 - 0.0011 18.2 0.4 0.16 11.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Bromodomain PF00439.20 EDP44984.1 - 0.0026 17.6 0.3 0.0065 16.3 0.2 1.6 1 0 0 1 1 1 1 Bromodomain AAA_25 PF13481.1 EDP44984.1 - 0.0047 16.3 0.1 0.024 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP44984.1 - 0.0054 15.7 0.0 0.56 9.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EDP44984.1 - 0.012 15.9 1.8 0.049 13.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.21 EDP44984.1 - 0.014 14.8 0.0 0.63 9.5 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 EDP44984.1 - 0.014 14.6 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 EDP44984.1 - 0.016 15.9 0.0 0.016 15.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.12 EDP44984.1 - 0.017 14.0 0.0 1.7 7.4 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 EDP44984.1 - 0.02 14.8 0.0 0.082 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EDP44984.1 - 0.022 14.9 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 1 0 RNA helicase TIP49 PF06068.8 EDP44984.1 - 0.026 13.2 0.0 0.065 11.9 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 EDP44984.1 - 0.055 13.7 0.0 0.39 11.0 0.0 2.5 2 0 0 2 2 1 0 ABC transporter Torsin PF06309.6 EDP44984.1 - 0.072 12.9 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_11 PF13086.1 EDP44984.1 - 0.098 12.2 3.3 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain FliT PF05400.8 EDP44984.1 - 5 7.5 13.7 0.37 11.2 0.2 3.4 3 0 0 3 3 3 0 Flagellar protein FliT DnaJ PF00226.26 EDP44985.1 - 3.5e-26 90.7 3.4 5.3e-26 90.1 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDP44985.1 - 2.1e-14 53.1 0.9 6.7e-12 45.1 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain Ribosomal_L7Ae PF01248.21 EDP44986.1 - 3.4e-27 93.7 0.2 4.4e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDP44986.1 - 0.0075 16.1 0.1 0.0091 15.8 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EDP44986.1 - 0.042 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 EDP44986.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Arrestin_N PF00339.24 EDP44987.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain RabGAP-TBC PF00566.13 EDP44988.1 - 6.1e-16 58.5 0.0 1.6e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CRAL_TRIO PF00650.15 EDP44989.1 - 4.9e-28 97.6 0.0 7.4e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EDP44989.1 - 5.3e-07 29.6 0.0 8.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDP44989.1 - 1e-06 28.7 0.6 1e-06 28.7 0.4 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Gly-zipper_OmpA PF13436.1 EDP44989.1 - 0.65 9.6 16.7 0.33 10.6 2.4 2.6 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Lipase_3 PF01764.20 EDP44990.1 - 8e-25 87.0 0.0 1.2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EDP44990.1 - 0.0014 18.5 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP44990.1 - 0.0033 17.2 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EDP44990.1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FSH1 PF03959.8 EDP44990.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.3 EDP44990.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EDP44990.1 - 0.024 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EDP44990.1 - 0.031 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EDP44990.1 - 0.05 11.9 0.0 0.07 11.4 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF726 PF05277.7 EDP44990.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 EDP44990.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDP44991.1 - 1.7e-27 95.7 0.0 2.4e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EDP44991.1 - 0.022 14.1 0.0 0.046 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.8 EDP44991.1 - 0.032 12.5 0.0 0.047 11.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EDP44991.1 - 0.056 13.3 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDP44992.1 - 6.5e-26 90.6 0.0 8.9e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.8 EDP44992.1 - 0.00045 18.6 0.0 0.00066 18.0 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EDP44992.1 - 0.00055 19.8 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EDP44992.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EDP44992.1 - 0.016 14.9 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDP44992.1 - 0.026 14.1 0.1 0.071 12.6 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EDP44992.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EDP44993.1 - 1.3e-22 79.8 0.0 1.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EDP44993.1 - 0.00011 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDP44993.1 - 0.003 17.3 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EDP44993.1 - 0.0043 16.2 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Lipase_2 PF01674.13 EDP44993.1 - 0.0072 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) FSH1 PF03959.8 EDP44993.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EDP44993.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EDP44993.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.8 EDP44993.1 - 0.039 12.2 0.0 0.055 11.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.9 EDP44993.1 - 0.039 13.2 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EDP44993.1 - 0.047 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 EDP44993.1 - 0.062 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 EDP44993.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) PFK PF00365.15 EDP44994.1 - 2.6e-145 482.6 1.5 1.1e-92 310.0 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase GATase PF00117.23 EDP44994.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I PapJ PF14855.1 EDP44994.1 - 0.052 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone GvpL_GvpF PF06386.6 EDP44995.1 - 0.026 14.1 0.3 0.03 13.9 0.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_1 PF00170.16 EDP44995.1 - 0.033 14.1 3.5 0.048 13.6 0.9 2.3 2 1 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 EDP44995.1 - 1.8 8.5 4.1 18 5.3 0.3 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Dzip-like_N PF13815.1 EDP44995.1 - 3.2 7.5 6.9 8.5 6.2 0.1 2.3 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Arf PF00025.16 EDP44996.1 - 4.3e-27 94.4 0.1 3.8e-14 52.3 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EDP44996.1 - 4.6e-06 26.1 0.0 0.00035 20.0 0.0 2.1 2 0 0 2 2 2 2 Ras family G-alpha PF00503.15 EDP44996.1 - 0.0002 20.2 0.0 0.00048 18.9 0.0 1.6 2 0 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EDP44996.1 - 0.0013 19.2 0.0 0.07 13.6 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EDP44996.1 - 0.073 12.1 0.0 0.094 11.8 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2370 PF10176.4 EDP44997.1 - 7.1e-54 182.6 1.8 6.8e-53 179.3 1.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF410 PF04190.8 EDP44998.1 - 4.3e-23 82.1 1.7 1.9e-19 70.2 0.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF410) TPR_14 PF13428.1 EDP44998.1 - 0.056 14.0 0.7 0.21 12.3 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GMP_synt_C PF00958.17 EDP44998.1 - 0.081 12.6 0.0 2.8 7.7 0.0 2.3 1 1 0 1 1 1 0 GMP synthase C terminal domain PROCN PF08083.6 EDP44999.1 - 1.3e-209 695.7 5.6 1.9e-209 695.2 3.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EDP44999.1 - 5e-126 418.6 0.4 8e-126 417.9 0.3 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EDP44999.1 - 6.5e-90 298.6 0.4 1.9e-89 297.1 0.3 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EDP44999.1 - 4.3e-79 263.4 5.7 5.5e-79 263.1 2.0 2.4 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EDP44999.1 - 5.2e-67 223.6 0.0 9.5e-67 222.7 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EDP44999.1 - 1.2e-42 143.6 0.2 2.7e-42 142.5 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EDP44999.1 - 6.5e-31 106.6 0.0 1.2e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EDP44999.1 - 0.0016 18.1 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SCP-1 PF05483.7 EDP44999.1 - 0.3 8.8 0.1 0.43 8.2 0.0 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DUF3722 PF12519.3 EDP45000.1 - 1.2e-24 86.9 0.1 5.5e-23 81.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) DUF3402 PF11882.3 EDP45001.1 - 7.6e-115 384.2 0.0 1.4e-114 383.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EDP45001.1 - 3.1e-16 59.0 0.0 5.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein DDOST_48kD PF03345.9 EDP45002.1 - 1.6e-92 310.2 0.0 4e-92 308.9 0.0 1.5 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ATP_bind_4 PF01902.12 EDP45003.1 - 0.00031 20.1 0.1 0.018 14.3 0.0 2.0 2 0 0 2 2 2 2 ATP-binding region SUV3_C PF12513.3 EDP45004.1 - 5e-15 54.6 0.2 9.3e-15 53.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EDP45004.1 - 1.7e-12 47.0 0.1 8.7e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromo_TP PF07524.8 EDP45005.1 - 2.3e-05 24.0 0.2 4.3e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EDP45005.1 - 0.017 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF3808 PF10300.4 EDP45006.1 - 1.9e-23 82.8 0.2 2.6e-23 82.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EDP45006.1 - 2.4e-06 27.0 6.5 0.0012 18.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDP45006.1 - 2.4e-05 24.1 2.7 0.0043 16.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDP45006.1 - 0.00012 21.5 4.6 0.018 14.6 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDP45006.1 - 0.00042 19.9 10.0 0.03 13.9 0.1 3.3 3 1 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 EDP45006.1 - 0.00042 20.5 2.5 0.06 13.8 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDP45006.1 - 0.00043 20.5 0.7 0.044 14.1 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDP45006.1 - 0.0014 18.8 1.5 0.14 12.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDP45006.1 - 0.0021 18.5 0.2 0.13 12.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDP45006.1 - 0.0026 18.3 0.4 0.3 11.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDP45006.1 - 0.003 17.4 1.5 0.47 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDP45006.1 - 0.016 14.9 3.6 0.042 13.6 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP45006.1 - 0.017 14.8 1.9 0.79 9.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDP45006.1 - 0.04 14.0 2.3 5.4 7.2 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDP45006.1 - 0.042 13.7 1.6 0.31 10.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDP45006.1 - 0.22 11.8 1.6 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EDP45007.1 - 6.5e-33 114.0 0.0 3.2e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Peptidase_S10 PF00450.17 EDP45008.1 - 4.5e-82 276.4 1.4 5.7e-82 276.1 1.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_1 PF00232.13 EDP45008.1 - 0.079 11.1 0.1 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Polysacc_deac_1 PF01522.16 EDP45009.1 - 8.6e-28 96.4 0.0 1.6e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 3Beta_HSD PF01073.14 EDP45010.1 - 1.5e-22 79.6 0.0 3e-22 78.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDP45010.1 - 1.6e-22 80.0 0.5 3.5e-22 78.9 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDP45010.1 - 4.5e-19 69.1 0.0 8.1e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDP45010.1 - 2.7e-13 49.4 0.0 8.8e-07 28.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EDP45010.1 - 1.6e-12 47.1 0.4 6e-12 45.3 0.4 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDP45010.1 - 5.6e-12 45.1 0.3 1.2e-11 44.1 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDP45010.1 - 3e-07 30.5 0.1 1.3e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP45010.1 - 3.6e-05 23.5 0.1 0.00017 21.3 0.0 1.9 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EDP45010.1 - 0.00049 19.0 0.8 0.0024 16.8 0.2 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.15 EDP45010.1 - 0.019 14.9 0.2 0.062 13.2 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EDP45010.1 - 0.02 15.1 0.1 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Treacle PF03546.9 EDP45010.1 - 0.13 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle DUF4646 PF15496.1 EDP45011.1 - 0.03 14.3 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) ADH_zinc_N PF00107.21 EDP45012.1 - 5.9e-21 74.3 0.1 9.4e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDP45012.1 - 1.5e-16 60.0 2.5 3.3e-16 58.9 0.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 EDP45013.1 - 1.3e-06 28.0 22.5 0.0043 16.8 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Myosin_tail_1 PF01576.14 EDP45014.1 - 0.025 12.3 52.0 0.0038 15.0 30.6 2.0 1 1 1 2 2 2 0 Myosin tail GAS PF13851.1 EDP45014.1 - 4.9 6.2 44.1 0.48 9.5 3.1 4.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EDP45015.1 - 1.5e-13 50.9 16.6 1.5e-13 50.9 11.5 2.2 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding DUF1515 PF07439.6 EDP45015.1 - 0.33 10.7 3.3 0.22 11.3 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DDE_Tnp_IS240 PF13610.1 EDP45015.1 - 0.89 9.5 6.5 1.1 9.2 0.8 2.8 2 1 1 3 3 3 0 DDE domain P5-ATPase PF12409.3 EDP45016.1 - 3.1e-31 107.6 0.0 7.1e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EDP45016.1 - 5.9e-26 91.8 0.0 1.1e-25 90.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDP45016.1 - 1.5e-25 89.5 0.0 3.1e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDP45016.1 - 7e-24 85.4 0.0 1.3e-22 81.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDP45016.1 - 2.7e-06 27.2 0.0 7.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDP45016.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDP45016.1 - 0.29 10.6 0.0 0.76 9.2 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA_bind PF01588.15 EDP45017.1 - 2.2e-26 91.5 0.0 3.3e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EDP45017.1 - 3.3e-05 24.2 0.0 6.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDP45017.1 - 0.00018 21.2 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDP45017.1 - 0.0098 15.8 0.3 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain KOW PF00467.24 EDP45017.1 - 0.12 12.1 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 KOW motif UDPGP PF01704.13 EDP45018.1 - 1.2e-49 168.9 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EDP45018.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain COG2 PF06148.6 EDP45019.1 - 8.1e-20 71.0 0.4 2.4e-19 69.5 0.1 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EDP45019.1 - 9e-10 38.7 0.0 2.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 EDP45019.1 - 0.00059 19.6 0.9 0.0023 17.7 0.2 2.5 2 0 0 2 2 2 1 Vps51/Vps67 CAP59_mtransfer PF11735.3 EDP45020.1 - 2.1e-68 230.1 0.0 2.8e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Pkinase PF00069.20 EDP45021.1 - 2.1e-69 233.5 0.0 3.1e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45021.1 - 4.9e-47 160.1 0.0 7.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDP45021.1 - 1.2e-19 70.4 0.0 3.3e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EDP45021.1 - 4.9e-06 25.7 0.0 9.9e-06 24.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP45021.1 - 0.027 14.1 0.1 0.098 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 EDP45021.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 EDP45021.1 - 0.22 10.5 0.0 0.92 8.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rad9 PF04139.8 EDP45022.1 - 9.1e-39 133.0 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Trp_syntA PF00290.15 EDP45023.1 - 1e-74 250.3 0.0 1.8e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EDP45023.1 - 6.5e-41 140.5 0.5 1.1e-40 139.8 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Symplekin_C PF12295.3 EDP45024.1 - 2.2e-53 180.8 0.0 5.8e-53 179.5 0.0 1.7 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EDP45024.1 - 1.2e-37 129.6 0.0 3.3e-37 128.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) V-ATPase_G PF03179.10 EDP45025.1 - 3.7e-28 97.8 18.9 4.3e-28 97.6 13.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EDP45025.1 - 6.9e-05 22.1 20.0 7.7e-05 21.9 13.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 EDP45025.1 - 0.00034 20.4 10.5 0.00034 20.4 7.3 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) HrpE PF06188.7 EDP45025.1 - 0.019 14.7 5.8 0.024 14.3 4.0 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF842 PF05811.8 EDP45025.1 - 0.022 14.2 1.4 0.027 13.9 1.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.13 EDP45025.1 - 0.026 14.0 10.1 0.035 13.6 7.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain vATP-synt_E PF01991.13 EDP45025.1 - 0.038 13.2 16.6 0.047 12.9 11.5 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF883 PF05957.8 EDP45025.1 - 0.06 13.7 8.0 0.22 11.9 4.6 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3435 PF11917.3 EDP45025.1 - 0.065 11.9 8.6 0.075 11.7 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) SF-assemblin PF06705.6 EDP45025.1 - 0.1 11.7 13.5 0.17 10.9 9.3 1.4 1 1 0 1 1 1 0 SF-assemblin/beta giardin Ribosomal_L12 PF00542.14 EDP45025.1 - 0.13 12.3 13.4 0.44 10.5 0.4 2.4 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Peptidase_S46 PF10459.4 EDP45025.1 - 0.16 10.3 7.8 0.17 10.2 5.4 1.0 1 0 0 1 1 1 0 Peptidase S46 ATP11 PF06644.6 EDP45025.1 - 0.17 11.3 12.3 0.2 11.1 8.5 1.1 1 0 0 1 1 1 0 ATP11 protein Uteroglobin PF01099.12 EDP45025.1 - 0.27 11.0 3.2 0.53 10.1 1.9 1.9 1 1 0 1 1 1 0 Uteroglobin family Malate_synthase PF01274.17 EDP45025.1 - 0.28 9.1 3.5 0.33 8.9 2.5 1.0 1 0 0 1 1 1 0 Malate synthase DUF2115 PF09888.4 EDP45025.1 - 0.38 10.8 6.0 0.49 10.4 4.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Herpes_env PF01673.13 EDP45025.1 - 0.43 9.0 4.1 0.45 9.0 2.9 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Retrotrans_gag PF03732.12 EDP45025.1 - 0.46 10.5 5.7 0.72 9.9 3.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein Exonuc_VII_L PF02601.10 EDP45025.1 - 0.61 9.2 9.8 0.67 9.0 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phasin PF05597.6 EDP45025.1 - 0.63 9.7 11.4 5 6.8 7.9 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF342 PF03961.8 EDP45025.1 - 0.66 8.3 12.0 0.71 8.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3086 PF11285.3 EDP45025.1 - 1.1 7.9 5.8 2.7 6.7 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Muted PF14942.1 EDP45025.1 - 1.1 9.1 15.6 1.7 8.5 9.0 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein U79_P34 PF03064.11 EDP45025.1 - 1.6 8.1 9.3 1.8 7.9 6.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MMR_HSR1_C PF08438.5 EDP45025.1 - 2 8.6 6.0 3.6 7.8 4.0 1.6 1 1 0 1 1 1 0 GTPase of unknown function C-terminal RRF PF01765.14 EDP45025.1 - 2.1 7.8 16.5 3.6 7.0 11.5 1.5 1 1 0 1 1 1 0 Ribosome recycling factor She9_MDM33 PF05546.6 EDP45025.1 - 2.1 7.8 12.0 3.2 7.2 8.3 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family DUF2422 PF10337.4 EDP45025.1 - 2.4 6.8 4.0 2.9 6.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PhoU PF01895.14 EDP45025.1 - 2.4 8.6 5.6 1.3 9.4 0.1 2.2 1 1 1 2 2 2 0 PhoU domain Spore_III_AB PF09548.5 EDP45025.1 - 2.5 7.8 7.7 5.4 6.7 5.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) OmpH PF03938.9 EDP45025.1 - 2.7 7.9 17.3 3.5 7.5 12.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spore_GerAC PF05504.6 EDP45025.1 - 2.9 7.6 12.4 27 4.5 8.6 2.1 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal FliD_C PF07195.7 EDP45025.1 - 2.9 7.1 9.8 1.9 7.7 3.9 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMPIT PF07851.8 EDP45025.1 - 2.9 6.8 10.7 3.6 6.5 7.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 EDP45025.1 - 3.5 6.4 8.8 4.3 6.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mt_ATP-synt_D PF05873.7 EDP45025.1 - 4.8 6.7 12.7 8.9 5.9 4.4 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) HSCB_C PF07743.8 EDP45025.1 - 6.1 7.3 12.9 0.73 10.3 2.2 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Jnk-SapK_ap_N PF09744.4 EDP45025.1 - 7.1 6.6 17.0 13 5.7 11.7 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 ATP-synt_F6 PF05511.6 EDP45025.1 - 9 6.2 8.8 2.3 8.1 1.4 2.2 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 APG6 PF04111.7 EDP45025.1 - 9.7 5.1 15.8 12 4.8 10.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 YgaB PF14182.1 EDP45025.1 - 9.8 6.4 13.3 80 3.5 9.2 2.2 1 1 0 1 1 1 0 YgaB-like protein WD40 PF00400.27 EDP45026.1 - 6.8e-06 25.7 1.7 2.2e-05 24.1 0.2 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat MutL_C PF08676.6 EDP45027.1 - 1.8e-19 69.7 0.0 4.2e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EDP45027.1 - 3.8e-19 68.2 0.0 1.2e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EDP45027.1 - 7.7e-14 51.5 0.1 1.9e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDP45027.1 - 3e-10 39.7 0.0 6.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MDMPI_C PF07398.6 EDP45028.1 - 0.038 14.5 1.9 0.076 13.5 0.9 1.8 2 0 0 2 2 2 0 MDMPI C-terminal domain Dynamitin PF04912.9 EDP45028.1 - 0.061 12.1 0.5 0.084 11.6 0.4 1.3 1 0 0 1 1 1 0 Dynamitin Dynein_light PF01221.13 EDP45029.1 - 1.3e-34 118.0 0.1 1.6e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 EDP45029.1 - 0.062 12.8 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 28 IF-2B PF01008.12 EDP45030.1 - 2.8e-71 239.8 0.0 3.9e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family BAR PF03114.13 EDP45031.1 - 1.4e-26 93.4 1.8 2.2e-26 92.7 1.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EDP45031.1 - 4.2e-15 54.8 0.0 6.5e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDP45031.1 - 4.8e-14 51.6 0.1 7.4e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDP45031.1 - 8.8e-11 41.1 0.0 1.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DEC-1_N PF04625.8 EDP45031.1 - 3.6 6.1 8.5 5.2 5.6 5.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_62 PF03664.8 EDP45032.1 - 0.017 14.2 0.2 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 ComFB PF10719.4 EDP45032.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB PBP1_TM PF14812.1 EDP45032.1 - 1.8 8.9 12.3 1.9 8.8 3.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 EDP45032.1 - 6.2 6.3 10.2 7.4 6.1 2.4 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PP_M1 PF03012.9 EDP45032.1 - 7 5.9 7.6 1.4 8.2 1.2 2.0 2 0 0 2 2 2 0 Phosphoprotein RabGAP-TBC PF00566.13 EDP45033.1 - 2e-25 89.5 1.1 7.9e-25 87.5 0.7 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SWI-SNF_Ssr4 PF08549.5 EDP45034.1 - 0.00019 19.9 0.1 0.00019 19.9 0.1 2.2 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1750) Borrelia_P83 PF05262.6 EDP45034.1 - 1.1 7.4 14.2 1.9 6.6 9.8 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 EDP45034.1 - 3.2 5.8 29.8 4 5.5 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 EDP45034.1 - 4.1 7.2 12.5 6.1 6.6 8.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DnaJ PF00226.26 EDP45035.1 - 1.4e-21 75.9 0.4 2.1e-21 75.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain HEAT_EZ PF13513.1 EDP45036.1 - 9.1e-23 80.1 14.1 1.8e-06 28.2 0.0 11.1 8 3 5 13 13 13 4 HEAT-like repeat HEAT_2 PF13646.1 EDP45036.1 - 2.8e-15 56.3 27.7 0.0014 18.8 0.0 8.1 4 3 4 9 9 9 7 HEAT repeats HEAT PF02985.17 EDP45036.1 - 1.1e-14 53.0 10.7 0.0038 17.1 0.0 9.6 10 0 0 10 10 9 3 HEAT repeat Ipi1_N PF12333.3 EDP45036.1 - 7.1e-09 35.5 5.1 0.0038 17.1 0.0 6.1 5 1 1 6 6 6 3 Rix1 complex component involved in 60S ribosome maturation IBN_N PF03810.14 EDP45036.1 - 6e-08 32.5 1.4 4.5e-07 29.6 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EDP45036.1 - 1.4e-06 28.5 0.1 1.4 9.3 0.0 6.0 6 1 0 6 6 5 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EDP45036.1 - 1.5e-05 24.8 0.1 0.25 11.2 0.0 5.4 5 2 0 5 5 5 1 UME (NUC010) domain Xpo1 PF08389.7 EDP45036.1 - 7.1e-05 22.7 12.1 0.1 12.5 1.3 5.7 5 1 0 5 5 5 2 Exportin 1-like protein CLASP_N PF12348.3 EDP45036.1 - 0.00015 21.2 5.1 0.5 9.6 0.0 5.1 4 1 0 5 5 5 2 CLASP N terminal MMS19_C PF12460.3 EDP45036.1 - 0.00025 19.8 6.4 3 6.4 0.3 5.2 5 1 1 7 7 7 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EDP45036.1 - 0.0014 17.9 4.2 0.051 12.8 0.5 3.9 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.2 EDP45036.1 - 0.0045 16.9 0.2 5 7.1 0.0 3.4 3 0 0 3 3 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EDP45036.1 - 0.021 14.6 0.1 6.9 6.4 0.0 4.3 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EDP45036.1 - 0.037 13.9 0.4 21 5.0 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) Pkinase PF00069.20 EDP45037.1 - 5.9e-58 196.0 0.0 8.6e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45037.1 - 1.7e-20 73.1 0.0 2.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP45037.1 - 0.00032 20.5 0.1 0.0045 16.7 0.0 2.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDP45037.1 - 0.0032 16.8 0.4 0.0081 15.5 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EDP45037.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EDP45037.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Med4 PF10018.4 EDP45038.1 - 4.2e-22 78.4 9.2 4.2e-22 78.4 6.4 1.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 CEP19 PF14933.1 EDP45038.1 - 7 6.9 9.9 52 4.1 6.9 2.3 1 1 0 1 1 1 0 CEP19-like protein G-patch PF01585.18 EDP45039.1 - 1.5e-09 37.4 0.4 2.5e-09 36.7 0.3 1.3 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EDP45039.1 - 9.9e-05 22.1 0.0 0.00037 20.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP45039.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP45039.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_fiss_reg PF05308.6 EDP45039.1 - 0.14 11.5 3.8 0.2 10.9 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA PF00004.24 EDP45040.1 - 1.6e-41 141.5 0.0 3e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDP45040.1 - 2.3e-05 24.1 1.7 0.00015 21.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDP45040.1 - 3.4e-05 23.8 0.1 0.0004 20.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDP45040.1 - 7.2e-05 22.8 0.1 0.0084 16.1 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDP45040.1 - 0.00015 21.9 0.7 0.014 15.4 0.5 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDP45040.1 - 0.00022 20.3 0.0 0.00062 18.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EDP45040.1 - 0.00088 18.5 0.1 0.0078 15.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 EDP45040.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP45040.1 - 0.0027 18.5 0.0 0.0075 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDP45040.1 - 0.0096 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDP45040.1 - 0.012 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EDP45040.1 - 0.014 14.3 0.3 0.03 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EDP45040.1 - 0.014 14.5 0.1 0.041 13.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDP45040.1 - 0.019 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TMF_TATA_bd PF12325.3 EDP45040.1 - 0.024 14.3 2.6 0.024 14.3 1.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_24 PF13479.1 EDP45040.1 - 0.051 13.1 0.3 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EDP45040.1 - 0.062 12.6 3.0 0.36 10.1 0.1 2.6 2 1 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EDP45040.1 - 0.11 12.0 0.0 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EDP45040.1 - 0.12 11.4 0.6 0.37 9.8 0.0 2.1 3 0 0 3 3 3 0 KaiC Kinesin PF00225.18 EDP45041.1 - 2.2e-96 322.4 0.0 3.2e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 EDP45041.1 - 0.059 13.1 0.5 5.3 7.0 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FlgN PF05130.7 EDP45041.1 - 0.11 12.6 15.6 0.027 14.7 4.6 3.0 2 1 0 2 2 2 0 FlgN protein TPR_MLP1_2 PF07926.7 EDP45041.1 - 0.12 12.1 0.2 0.12 12.1 0.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 EDP45041.1 - 4.8 5.4 13.5 1.6 7.1 6.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family PRP38 PF03371.10 EDP45042.1 - 3.8e-64 215.4 0.0 5e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family AA_permease PF00324.16 EDP45043.1 - 4.2e-62 210.0 30.7 5.2e-62 209.7 21.3 1.1 1 0 0 1 1 1 1 Amino acid permease Myosin_head PF00063.16 EDP45044.1 - 1.8e-236 786.5 0.0 2.7e-236 785.9 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EDP45044.1 - 6.4e-36 122.4 2.4 2.2e-35 120.7 1.7 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EDP45044.1 - 2.3e-05 23.6 41.6 0.028 14.0 0.8 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EDP45044.1 - 0.0004 20.5 0.3 0.003 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EDP45044.1 - 0.0024 17.1 2.1 0.0042 16.3 1.4 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EDP45044.1 - 0.029 14.2 16.5 0.11 12.3 11.3 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNA_helicase PF00910.17 EDP45044.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EDP45044.1 - 0.13 11.6 3.6 0.51 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Fzo_mitofusin PF04799.8 EDP45044.1 - 0.31 10.3 10.2 0.028 13.8 2.4 2.4 1 1 1 2 2 2 0 fzo-like conserved region APG6 PF04111.7 EDP45044.1 - 0.36 9.8 13.5 0.77 8.7 9.4 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EDP45044.1 - 0.54 9.7 23.6 0.11 12.0 1.6 4.4 4 1 1 5 5 5 0 Septum formation initiator AAA_23 PF13476.1 EDP45044.1 - 0.56 10.5 3.7 35 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.6 EDP45044.1 - 0.78 9.6 3.6 19 5.2 0.3 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 EDP45044.1 - 1.6 7.0 8.5 5.8 5.2 5.9 1.7 1 1 0 1 1 1 0 AAA domain Desmo_N PF06771.6 EDP45044.1 - 1.6 8.6 4.4 7.3 6.5 0.2 3.7 4 0 0 4 4 4 0 Viral Desmoplakin N-terminus Sec2p PF06428.6 EDP45044.1 - 1.7 8.5 10.1 0.19 11.5 1.7 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Seryl_tRNA_N PF02403.17 EDP45044.1 - 2.1 8.3 7.9 4.1 7.4 4.2 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EDP45044.1 - 2.1 7.8 24.9 7.6 6.0 17.1 2.0 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 EDP45044.1 - 2.7 6.3 8.5 0.66 8.3 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EDP45044.1 - 3.4 7.4 8.5 6.7 6.4 0.9 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 EDP45044.1 - 4.7 7.3 11.0 0.82 9.7 4.4 2.2 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family TPR_19 PF14559.1 EDP45045.1 - 0.00021 21.5 0.4 0.06 13.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4205 PF13898.1 EDP45045.1 - 0.00022 20.0 0.2 0.0003 19.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) TPR_14 PF13428.1 EDP45045.1 - 0.0093 16.5 0.1 2.3 9.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDP45045.1 - 0.024 15.2 0.0 10 6.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDP45045.1 - 0.03 14.2 0.9 0.053 13.4 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDP45045.1 - 0.1 13.1 0.0 5.6 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3128 PF11326.3 EDP45045.1 - 0.28 11.3 1.4 9.8 6.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) FUN14 PF04930.10 EDP45046.1 - 2.9e-20 72.4 0.1 4.5e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 FUN14 family UPF0029 PF01205.14 EDP45047.1 - 5.3e-14 51.8 0.0 9.6e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Herpes_UL35 PF04496.7 EDP45047.1 - 0.0088 16.2 0.5 0.014 15.5 0.3 1.4 1 0 0 1 1 1 1 Herpesvirus UL35 family Fungal_trans PF04082.13 EDP45048.1 - 1.4e-11 43.7 0.2 2.5e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHF5 PF03660.9 EDP45049.1 - 2e-15 56.7 0.3 2.2e-15 56.6 0.2 1.0 1 0 0 1 1 1 1 PHF5-like protein Pkinase PF00069.20 EDP45050.1 - 3.1e-62 210.0 0.0 2.5e-37 128.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45050.1 - 1.6e-20 73.2 0.0 1.1e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45050.1 - 0.00088 18.3 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP45050.1 - 0.0017 18.1 0.6 0.0017 18.1 0.4 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EDP45050.1 - 0.0023 17.0 0.3 0.0048 15.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDP45050.1 - 0.012 14.9 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Tropomyosin_1 PF12718.2 EDP45051.1 - 3.3e-45 153.4 32.4 4e-45 153.1 22.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EDP45051.1 - 2.8e-12 46.2 32.6 0.00016 20.8 7.2 3.0 1 1 2 3 3 3 3 Tropomyosin Myosin_tail_1 PF01576.14 EDP45051.1 - 0.001 16.9 34.7 0.0014 16.4 24.1 1.3 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 EDP45051.1 - 0.0022 16.5 32.7 0.058 11.8 13.6 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light Striatin PF08232.7 EDP45051.1 - 0.0027 17.9 24.8 0.061 13.6 8.6 2.1 1 1 1 2 2 2 2 Striatin family Cast PF10174.4 EDP45051.1 - 0.0033 15.5 17.8 0.0033 15.5 12.4 2.0 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone FliJ PF02050.11 EDP45051.1 - 0.0048 16.9 16.1 0.0048 16.9 11.2 2.4 1 1 1 2 2 2 1 Flagellar FliJ protein CCDC-167 PF15188.1 EDP45051.1 - 0.0071 16.2 5.5 0.0071 16.2 3.8 3.5 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 DUF4200 PF13863.1 EDP45051.1 - 0.011 15.7 31.6 0.32 10.9 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.1 EDP45051.1 - 0.015 15.2 11.1 0.015 15.2 7.7 2.8 1 1 2 3 3 3 0 FlxA-like protein FliD_C PF07195.7 EDP45051.1 - 0.017 14.4 17.4 0.031 13.5 4.0 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus ERM PF00769.14 EDP45051.1 - 0.068 12.6 33.9 0.032 13.7 20.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EDP45051.1 - 0.075 12.8 33.6 0.45 10.3 6.9 3.0 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EDP45051.1 - 0.097 12.5 7.0 0.16 11.8 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EDP45051.1 - 0.11 11.6 4.9 0.21 10.7 3.3 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 EDP45051.1 - 0.13 11.4 29.7 1.3 8.1 20.6 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 EDP45051.1 - 0.15 11.4 29.3 0.084 12.3 10.1 2.0 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.3 EDP45051.1 - 0.19 11.6 30.6 2.7 7.9 6.3 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 EDP45051.1 - 0.24 11.4 29.0 1.4 8.9 8.9 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EDP45051.1 - 0.27 11.0 25.4 0.033 14.0 6.3 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Fmp27_WPPW PF10359.4 EDP45051.1 - 0.32 9.3 26.4 0.56 8.5 5.6 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FH2 PF02181.18 EDP45051.1 - 0.33 9.7 13.1 0.015 14.2 3.0 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain TPR_MLP1_2 PF07926.7 EDP45051.1 - 0.38 10.4 33.5 2.9 7.6 16.3 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MtrB PF05440.7 EDP45051.1 - 0.41 10.7 1.6 1.3 9.0 0.1 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF641 PF04859.7 EDP45051.1 - 0.43 10.3 18.4 0.77 9.5 3.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EDP45051.1 - 0.62 9.8 35.3 0.53 10.1 9.2 3.6 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 EDP45051.1 - 0.65 9.6 23.4 0.36 10.4 3.4 3.9 1 1 3 4 4 4 0 Prefoldin subunit IncA PF04156.9 EDP45051.1 - 0.67 9.5 36.9 1.4 8.4 20.1 2.1 1 1 1 2 2 2 0 IncA protein DUF904 PF06005.7 EDP45051.1 - 0.7 10.2 35.2 35 4.7 11.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DASH_Hsk3 PF08227.6 EDP45051.1 - 0.77 9.9 9.1 1.8 8.7 1.7 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Clr5 PF14420.1 EDP45051.1 - 0.84 9.5 4.8 0.43 10.5 1.2 2.0 2 0 0 2 2 2 0 Clr5 domain Prefoldin_2 PF01920.15 EDP45051.1 - 1 9.1 30.6 2.5 7.8 1.8 3.9 1 1 2 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 EDP45051.1 - 1 9.4 17.3 2.6 8.1 1.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UvrD-helicase PF00580.16 EDP45051.1 - 1.1 8.5 11.2 1.3 8.2 7.7 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Adeno_PIX PF03955.9 EDP45051.1 - 1.1 9.8 17.2 0.7 10.4 2.6 3.0 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) Microtub_assoc PF07989.6 EDP45051.1 - 1.6 8.6 13.7 4.3 7.2 2.2 2.8 2 1 0 2 2 2 0 Microtubule associated DUF3584 PF12128.3 EDP45051.1 - 1.7 5.8 31.9 0.1 9.9 11.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EDP45051.1 - 2 8.2 13.5 1.4 8.7 2.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 EDP45051.1 - 2 8.3 25.6 0.79 9.6 9.2 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.7 EDP45051.1 - 2.1 8.6 7.8 11 6.3 1.5 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin_3 PF13758.1 EDP45051.1 - 2.1 8.1 17.1 0.66 9.7 4.8 2.9 2 2 0 2 2 2 0 Prefoldin subunit OEP PF02321.13 EDP45051.1 - 2.6 7.5 24.8 1.1 8.8 7.6 2.7 2 1 0 2 2 2 0 Outer membrane efflux protein HlyD PF00529.15 EDP45051.1 - 3.5 6.8 22.6 4.1 6.6 15.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein V_ATPase_I PF01496.14 EDP45051.1 - 3.7 5.2 17.8 3.9 5.2 11.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EDP45051.1 - 4.4 6.4 27.0 6.8 5.8 10.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6 PF04111.7 EDP45051.1 - 4.9 6.0 34.6 1.6 7.7 15.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EDP45051.1 - 5.1 7.5 19.8 5.3 7.5 4.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BRE1 PF08647.6 EDP45051.1 - 5.1 7.1 22.3 2.6 8.0 3.5 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.1 EDP45051.1 - 5.2 6.4 33.2 0.19 11.1 11.1 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.3 EDP45051.1 - 5.3 6.7 31.2 0.13 11.9 9.8 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EDP45051.1 - 6.2 6.3 25.2 5.4 6.5 6.3 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.6 EDP45051.1 - 6.3 5.1 25.5 14 3.9 17.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) PA26 PF04636.8 EDP45051.1 - 7 5.2 15.0 4.7 5.7 4.6 1.9 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Mnd1 PF03962.10 EDP45051.1 - 7.8 6.1 29.9 0.88 9.1 5.5 2.3 1 1 2 3 3 3 0 Mnd1 family DUF972 PF06156.8 EDP45051.1 - 8.1 6.8 23.9 6.1 7.2 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EDP45051.1 - 8.9 4.6 21.8 16 3.7 15.1 1.5 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EDP45051.1 - 8.9 6.8 26.2 3.2 8.2 4.3 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 EDP45051.1 - 9.2 5.1 22.1 70 2.2 15.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UQ_con PF00179.21 EDP45052.1 - 6.8e-46 155.1 0.0 7.7e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDP45052.1 - 0.037 13.9 1.5 0.074 12.9 1.0 1.8 1 1 0 1 1 1 0 RWD domain Glyco_transf_21 PF13506.1 EDP45053.1 - 2e-19 69.5 0.6 1.4e-12 47.2 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EDP45053.1 - 1e-11 45.0 0.1 2.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDP45053.1 - 0.0018 18.0 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 FGGY_C PF02782.11 EDP45054.1 - 9.3e-36 123.2 0.4 1.4e-35 122.7 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDP45054.1 - 1.7e-07 30.8 0.1 1.9e-05 24.1 0.0 2.6 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain UPF0075 PF03702.9 EDP45054.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) ADH_N PF08240.7 EDP45055.1 - 3e-27 94.5 0.6 5.8e-27 93.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDP45055.1 - 1.5e-22 79.4 0.1 3.3e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Arrestin_N PF00339.24 EDP45056.1 - 8e-07 28.9 0.0 6.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PDZ_2 PF13180.1 EDP45057.1 - 3.3e-08 33.2 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EDP45057.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EDP45057.1 - 0.032 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Spectrin PF00435.16 EDP45057.1 - 0.58 10.4 3.5 1.1 9.5 1.0 2.3 1 1 2 3 3 3 0 Spectrin repeat TraL PF07178.6 EDP45058.1 - 0.37 10.8 3.1 1.1 9.2 0.4 2.2 2 0 0 2 2 2 0 TraL protein Utp11 PF03998.8 EDP45059.1 - 1.1e-53 182.5 26.7 1.6e-53 182.0 18.5 1.3 1 0 0 1 1 1 1 Utp11 protein Acyl-CoA_dh_2 PF08028.6 EDP45059.1 - 0.68 10.1 8.5 2.2 8.5 5.9 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SPT6_acidic PF14632.1 EDP45059.1 - 2.6 8.2 10.6 0.42 10.8 0.8 3.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 MFS_1 PF07690.11 EDP45060.1 - 4e-25 88.2 37.8 6.7e-24 84.2 25.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EDP45060.1 - 0.00078 18.0 12.1 0.0042 15.6 0.3 2.8 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like Pkinase PF00069.20 EDP45061.1 - 7.8e-25 87.4 0.0 9.8e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45061.1 - 4.7e-10 38.9 0.0 6.2e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP45061.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDP45061.1 - 0.088 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ion_trans PF00520.26 EDP45062.1 - 1.3e-07 31.1 5.2 7.9e-07 28.5 1.4 2.1 2 0 0 2 2 2 2 Ion transport protein PIRT PF15099.1 EDP45062.1 - 1 8.5 3.4 1.7 7.9 2.3 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Hydrolase_6 PF13344.1 EDP45063.1 - 3.9e-29 100.5 0.0 7.6e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDP45063.1 - 2.7e-18 65.4 0.0 6.2e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDP45063.1 - 9.3e-11 42.5 0.0 1.5e-10 41.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDP45063.1 - 2.3e-09 37.7 0.1 0.00051 20.3 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EDP45063.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 EDP45063.1 - 0.1 11.9 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase BPL_LplA_LipB PF03099.14 EDP45064.1 - 4.4e-12 46.0 0.0 8.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_N PF09825.4 EDP45064.1 - 0.006 15.4 0.0 0.008 14.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal Cullin PF00888.17 EDP45065.1 - 1.9e-70 238.0 0.0 4.3e-70 236.9 0.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EDP45065.1 - 3.8e-17 61.8 0.7 1.1e-16 60.4 0.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF913 PF06025.7 EDP45066.1 - 1.9e-64 217.8 0.1 5.6e-61 206.3 0.1 3.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EDP45066.1 - 3.5e-51 174.4 0.0 6.7e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) UBA PF00627.26 EDP45066.1 - 1.2e-09 37.6 0.1 5.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain TH1 PF04858.8 EDP45066.1 - 0.022 12.9 0.1 0.038 12.1 0.1 1.3 1 0 0 1 1 1 0 TH1 protein DUF4414 PF14377.1 EDP45067.1 - 2.3e-09 37.1 0.2 2.3e-09 37.1 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) HOOK PF05622.7 EDP45068.1 - 0.0058 14.5 30.3 0.076 10.8 1.0 3.2 1 1 1 2 2 2 2 HOOK protein Laminin_II PF06009.7 EDP45068.1 - 0.017 14.8 0.9 0.017 14.8 0.6 3.7 2 1 3 5 5 5 0 Laminin Domain II DUF972 PF06156.8 EDP45068.1 - 0.056 13.7 25.6 2.6 8.4 1.8 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EDP45068.1 - 0.077 12.8 40.2 0.095 12.5 7.1 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EDP45068.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.0 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EDP45068.1 - 2.9 7.4 42.6 0.021 14.4 13.5 3.1 1 1 2 3 3 3 0 IncA protein DASH_Dad3 PF08656.5 EDP45068.1 - 3.3 7.4 18.7 4.3 7.0 1.6 4.7 3 1 1 4 4 4 0 DASH complex subunit Dad3 HSP70 PF00012.15 EDP45069.1 - 2e-271 901.2 6.5 2.2e-271 901.0 4.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDP45069.1 - 5.3e-15 54.8 0.1 1.9e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EDP45069.1 - 0.024 13.7 0.1 0.088 11.8 0.0 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Med28 PF11594.3 EDP45069.1 - 0.056 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Mediator complex subunit 28 FGGY_C PF02782.11 EDP45069.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EDP45069.1 - 0.26 11.1 5.0 3.3 7.5 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA zf-C3HC4 PF00097.20 EDP45070.1 - 0.00084 18.9 2.6 0.0015 18.1 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDP45070.1 - 0.0025 17.6 2.9 0.005 16.6 2.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EDP45070.1 - 0.016 15.0 0.6 0.016 15.0 0.4 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF393 PF04134.7 EDP45070.1 - 0.036 15.1 0.0 0.067 14.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF393 zf-C3HC4_2 PF13923.1 EDP45070.1 - 0.052 13.5 3.0 0.085 12.8 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDP45070.1 - 0.057 13.5 2.9 0.057 13.5 2.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDP45070.1 - 0.059 13.0 0.8 0.088 12.4 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDP45070.1 - 0.087 12.7 2.4 0.14 12.0 1.6 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDP45070.1 - 0.5 10.1 2.4 0.8 9.4 1.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain TFIIF_beta PF02270.10 EDP45071.1 - 5.9e-56 190.2 0.0 1.4e-53 182.4 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 EDP45071.1 - 0.023 14.7 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 IS66 C-terminal element Tol_Tol_Ttg2 PF05494.7 EDP45071.1 - 0.026 14.1 0.1 0.059 12.9 0.0 1.6 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 Aminotran_5 PF00266.14 EDP45072.1 - 5.6e-32 110.8 0.0 8.3e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.27 EDP45073.1 - 1.7e-05 24.5 0.0 0.0031 17.3 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Glyco_hydro_cc PF11790.3 EDP45074.1 - 6.9e-58 195.8 7.4 8.9e-58 195.5 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Spt20 PF12090.3 EDP45075.1 - 7.4e-25 87.3 0.0 3.1e-24 85.3 0.0 2.0 2 1 0 2 2 2 1 Spt20 family PINIT PF14324.1 EDP45076.1 - 1.9e-36 125.3 0.1 3.1e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EDP45076.1 - 7.3e-21 73.4 6.7 1.7e-20 72.2 4.6 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EDP45076.1 - 8.6e-08 31.5 2.1 1.8e-07 30.5 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EDP45076.1 - 0.005 16.3 0.1 1.3 8.6 0.0 2.7 2 0 0 2 2 2 2 SAP domain MgsA_C PF12002.3 EDP45077.1 - 4.4e-34 117.5 0.3 7.7e-34 116.7 0.2 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EDP45077.1 - 2.3e-13 50.4 0.1 4e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDP45077.1 - 1.1e-12 47.4 0.0 2.5e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDP45077.1 - 1.8e-08 34.5 1.7 7.7e-07 29.3 0.6 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDP45077.1 - 7e-08 32.2 0.1 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDP45077.1 - 8e-08 32.4 3.7 0.00045 20.2 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EDP45077.1 - 9.7e-08 31.9 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EDP45077.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDP45077.1 - 1.8e-05 24.0 0.5 0.039 13.1 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDP45077.1 - 6.7e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EDP45077.1 - 6.9e-05 22.8 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EDP45077.1 - 0.00026 20.4 0.1 0.18 11.2 0.1 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EDP45077.1 - 0.00028 20.5 0.0 0.0007 19.1 0.0 1.8 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EDP45077.1 - 0.00032 20.2 0.1 0.027 13.9 0.0 2.7 2 1 1 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EDP45077.1 - 0.00039 20.7 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP45077.1 - 0.00049 20.9 0.8 0.0035 18.1 0.5 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDP45077.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EDP45077.1 - 0.0013 18.4 1.1 0.0022 17.7 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_28 PF13521.1 EDP45077.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDP45077.1 - 0.0019 17.1 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EDP45077.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EDP45077.1 - 0.0032 17.3 1.7 0.0049 16.7 0.2 2.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP45077.1 - 0.0042 16.7 0.3 0.033 13.8 0.2 2.3 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EDP45077.1 - 0.0068 16.0 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EDP45077.1 - 0.017 15.2 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EDP45077.1 - 0.019 14.3 2.0 0.088 12.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.1 EDP45077.1 - 0.022 14.3 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase III, delta subunit MobB PF03205.9 EDP45077.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EDP45077.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EDP45077.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EDP45077.1 - 0.029 13.7 0.0 0.087 12.2 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EDP45077.1 - 0.043 13.3 0.1 0.18 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDP45077.1 - 0.056 13.1 0.0 0.34 10.5 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase KTI12 PF08433.5 EDP45077.1 - 0.072 12.2 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.10 EDP45077.1 - 0.11 11.2 0.0 10 4.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRPRB PF09439.5 EDP45077.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EDP45077.1 - 0.12 12.0 0.5 3.5 7.2 0.0 2.2 1 1 1 2 2 2 0 NTPase TIP49 PF06068.8 EDP45077.1 - 0.12 11.0 0.0 0.32 9.6 0.0 1.6 1 1 1 2 2 2 0 TIP49 C-terminus DUF543 PF04418.7 EDP45078.1 - 6.1e-29 99.7 0.1 1e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF883 PF05957.8 EDP45078.1 - 0.052 13.9 1.7 1.8 9.0 0.8 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EDP45078.1 - 4.3 7.7 9.8 0.42 10.9 2.1 2.4 2 1 0 2 2 2 0 YtxH-like protein zf-CpG_bind_C PF12269.3 EDP45079.1 - 2.4e-06 27.2 1.1 3.2e-06 26.7 0.2 1.6 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain Pkinase PF00069.20 EDP45080.1 - 0.00018 20.7 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EDP45081.1 - 7.9e-30 103.8 0.0 6.8e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45081.1 - 3.1e-12 46.1 0.0 3.2e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP45081.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDP45081.1 - 0.0047 15.9 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EDP45081.1 - 0.014 14.9 0.0 0.052 13.1 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase PEX11 PF05648.9 EDP45082.1 - 0.00021 20.6 0.1 0.00033 19.9 0.1 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_S17 PF00366.15 EDP45083.1 - 5.9e-15 55.0 0.5 9.3e-15 54.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Zds_C PF08632.5 EDP45084.1 - 1.7e-19 68.9 0.4 4e-19 67.7 0.3 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Smr PF01713.16 EDP45085.1 - 2.6e-12 46.7 0.2 1.3e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 EDP45085.1 - 1.3e-06 27.7 0.7 0.00033 20.0 0.1 2.9 3 0 0 3 3 3 2 CUE domain DUF1771 PF08590.5 EDP45085.1 - 0.0026 17.7 5.2 0.0026 17.7 3.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) MFS_1 PF07690.11 EDP45086.1 - 1.6e-22 79.7 25.0 1.6e-22 79.7 17.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP45086.1 - 2e-19 69.5 18.4 5.1e-18 64.8 12.7 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter XK-related PF09815.4 EDP45086.1 - 0.015 14.3 0.8 4.4 6.2 0.0 2.4 2 0 0 2 2 2 0 XK-related protein TMEM213 PF15192.1 EDP45086.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.1 3 0 0 3 3 3 0 TMEM213 family Urb2 PF10441.4 EDP45087.1 - 5.6e-30 104.6 0.1 9.7e-29 100.5 0.0 2.4 1 1 1 2 2 2 1 Urb2/Npa2 family DUF2454 PF10521.4 EDP45088.1 - 0.0043 16.0 3.9 0.97 8.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) AP2 PF00847.15 EDP45088.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AP2 domain Ribosomal_L36 PF00444.13 EDP45089.1 - 1.1e-21 76.4 9.1 1.2e-21 76.3 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 GATA PF00320.22 EDP45089.1 - 0.038 13.3 0.3 0.058 12.7 0.2 1.4 1 0 0 1 1 1 0 GATA zinc finger Crust_neurohorm PF01147.12 EDP45089.1 - 0.078 12.2 0.6 0.081 12.2 0.4 1.1 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family NTP_transferase PF00483.18 EDP45090.1 - 6.4e-40 137.0 0.0 9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 EDP45090.1 - 1.5e-06 27.9 0.2 2.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NIR_SIR PF01077.17 EDP45091.1 - 2.2e-45 153.8 0.0 7.5e-38 129.3 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 EDP45091.1 - 1.4e-28 99.7 0.0 3.8e-28 98.2 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.12 EDP45091.1 - 8.8e-26 89.3 0.0 1.2e-11 44.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 EDP45091.1 - 9e-06 25.3 0.5 2e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HtaA PF04213.8 EDP45091.1 - 0.049 13.8 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Htaa YwhD PF08741.5 EDP45091.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 YwhD family RNB PF00773.14 EDP45092.1 - 3e-89 299.5 0.0 4e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EDP45092.1 - 2.5e-11 43.8 0.7 8.6e-11 42.0 0.5 2.0 1 1 0 1 1 1 1 PIN domain NDK PF00334.14 EDP45093.1 - 8.5e-52 174.5 0.0 1.1e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TAFII55_N PF04658.8 EDP45094.1 - 1.5e-52 177.3 0.1 1.5e-52 177.3 0.1 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF1741 PF08427.5 EDP45095.1 - 4.5e-26 91.7 0.3 9.2e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Cation_efflux PF01545.16 EDP45096.1 - 3.4e-77 259.3 9.2 6.2e-77 258.4 6.4 1.3 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.11 EDP45096.1 - 0.00088 18.6 4.4 0.0026 17.1 3.0 1.8 1 0 0 1 1 1 1 High-affinity nickel-transport protein Zip PF02535.17 EDP45096.1 - 2.7 6.9 30.0 0.11 11.5 12.1 2.5 1 1 1 2 2 2 0 ZIP Zinc transporter RAI1 PF08652.6 EDP45097.1 - 2.3e-18 65.7 0.0 4.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GTP_EFTU PF00009.22 EDP45098.1 - 2.2e-55 186.9 0.0 3.3e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDP45098.1 - 2.1e-36 124.0 0.0 4.5e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDP45098.1 - 4.1e-17 62.0 1.1 1.1e-16 60.7 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDP45098.1 - 8.8e-05 22.0 0.2 8.8e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDP45098.1 - 0.0031 17.4 0.2 0.011 15.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase 5HT_transporter PF03491.8 EDP45098.1 - 0.019 15.0 0.4 0.082 13.0 0.0 2.2 3 0 0 3 3 3 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus NIF3 PF01784.13 EDP45098.1 - 0.099 12.2 0.3 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) WH1 PF00568.18 EDP45099.1 - 4.5e-20 71.4 0.0 6.7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EDP45099.1 - 0.005 16.3 0.2 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.8 EDP45099.1 - 0.013 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family UQ_con PF00179.21 EDP45100.1 - 3.8e-36 123.5 0.0 4.5e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDP45100.1 - 2.1e-05 24.2 0.0 2.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDP45100.1 - 0.0047 16.6 0.1 0.0098 15.5 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EDP45100.1 - 0.029 14.2 0.3 0.035 14.0 0.2 1.5 1 1 0 1 1 1 0 RWD domain DUF2841 PF11001.3 EDP45101.1 - 6.7e-39 132.6 0.7 1.3e-38 131.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) GATA PF00320.22 EDP45102.1 - 1.7e-28 97.6 16.7 3.5e-14 51.8 4.0 2.7 2 0 0 2 2 2 2 GATA zinc finger DZR PF12773.2 EDP45102.1 - 0.00081 19.1 5.7 0.25 11.1 0.2 3.2 1 1 1 2 2 2 2 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EDP45102.1 - 0.013 15.1 3.2 0.043 13.4 0.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EDP45102.1 - 0.013 14.7 6.5 0.067 12.5 0.1 3.3 2 1 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EDP45102.1 - 0.2 10.9 10.2 1.2 8.3 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.16 EDP45102.1 - 0.49 10.3 3.9 9.4 6.2 2.7 2.5 1 1 0 1 1 1 0 FYVE zinc finger His_Phos_1 PF00300.17 EDP45103.1 - 2e-25 89.7 0.0 2.4e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PEMT PF04191.8 EDP45104.1 - 6.7e-54 180.4 6.3 1.8e-31 108.4 0.5 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase DNA_pol_B PF00136.16 EDP45105.1 - 9.5e-82 275.2 0.0 1.3e-81 274.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDP45105.1 - 4e-23 81.7 0.0 2.6e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDP45105.1 - 7.1e-13 48.3 4.5 1.6e-12 47.2 3.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EDP45105.1 - 0.32 9.6 0.5 0.49 9.0 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral HEAT PF02985.17 EDP45106.1 - 8.7e-42 137.4 25.0 0.00012 21.8 0.0 12.9 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 EDP45106.1 - 2.4e-30 104.6 13.5 2.4e-07 30.9 0.0 6.5 3 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EDP45106.1 - 2.6e-15 56.5 2.1 0.00014 22.1 0.0 7.1 4 2 4 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDP45106.1 - 9.8e-10 38.6 21.3 0.02 15.4 0.1 9.0 5 3 4 9 9 9 3 HEAT-like repeat CLASP_N PF12348.3 EDP45106.1 - 3.1e-07 29.9 3.1 0.074 12.3 0.1 4.4 1 1 3 5 5 5 2 CLASP N terminal Adaptin_N PF01602.15 EDP45106.1 - 4.8e-07 28.4 9.5 0.0011 17.3 2.7 4.0 2 1 1 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EDP45106.1 - 1.1e-06 28.2 0.6 0.35 10.7 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EDP45106.1 - 0.0034 17.2 4.3 2.3 8.1 0.0 4.4 4 1 2 6 6 6 2 Protein of unknown function (DUF2435) Rho_N PF07498.7 EDP45106.1 - 0.16 11.7 0.5 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain CRAL_TRIO PF00650.15 EDP45107.1 - 2.5e-38 131.0 0.0 3.3e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EDP45107.1 - 7.4e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DSX_dimer PF08828.5 EDP45107.1 - 0.00076 18.9 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Doublesex dimerisation domain SURF4 PF02077.10 EDP45108.1 - 1.4e-70 237.7 7.8 1.5e-70 237.6 5.4 1.0 1 0 0 1 1 1 1 SURF4 family YhhN PF07947.9 EDP45108.1 - 3.7 6.8 13.4 3.9 6.8 0.3 2.2 1 1 0 2 2 2 0 YhhN-like protein DUF619 PF04768.8 EDP45109.1 - 7.5e-37 126.3 0.0 1.1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EDP45109.1 - 8.7e-22 77.6 0.0 3.1e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 EDP45109.1 - 1.1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 EDP45109.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Retrotrans_gag PF03732.12 EDP45111.1 - 0.026 14.5 0.3 0.051 13.6 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Pkinase PF00069.20 EDP45113.1 - 2.6e-46 157.8 0.0 3.1e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45113.1 - 6.6e-32 110.5 0.0 8.2e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDP45113.1 - 0.0057 15.7 0.5 0.0082 15.2 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M24 PF00557.19 EDP45114.1 - 9.1e-40 136.4 0.0 1.5e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDP45114.1 - 1.1e-27 97.0 0.0 2.5e-20 73.3 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain AdoHcyase PF05221.12 EDP45115.1 - 3.1e-141 468.9 0.0 3.7e-141 468.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EDP45115.1 - 3.1e-84 280.7 2.1 4.7e-84 280.1 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDP45115.1 - 9.9e-11 41.1 0.4 4e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EDP45115.1 - 9.3e-05 21.8 0.2 0.00015 21.2 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EDP45115.1 - 0.0013 18.6 0.1 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EDP45115.1 - 0.0049 16.4 0.2 0.0097 15.5 0.2 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.14 EDP45115.1 - 0.015 14.4 0.8 0.093 11.8 0.5 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EDP45115.1 - 0.015 15.4 0.2 0.029 14.4 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDP45115.1 - 0.016 15.4 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TMEM107 PF14995.1 EDP45115.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 3HCDH_N PF02737.13 EDP45115.1 - 0.097 12.3 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_1 PF00036.27 EDP45117.1 - 2.6e-25 85.7 9.6 2.4e-09 35.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDP45117.1 - 2.3e-22 78.9 7.9 1.5e-11 44.2 2.1 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDP45117.1 - 8.9e-21 71.8 8.1 4.3e-09 35.4 0.2 4.1 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EDP45117.1 - 3.2e-16 57.8 9.6 6.2e-06 25.3 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EDP45117.1 - 6.4e-16 57.7 13.4 8.9e-07 28.4 1.2 4.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EDP45117.1 - 5e-10 39.1 0.4 9.3e-06 25.4 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDP45117.1 - 9.1e-06 25.3 2.3 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EDP45117.1 - 0.023 14.2 0.0 0.12 11.8 0.0 2.1 3 0 0 3 3 3 0 Caleosin related protein TFIIA_gamma_N PF02268.11 EDP45118.1 - 1.3e-25 88.7 0.1 1.7e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EDP45118.1 - 1e-24 86.0 0.3 1.4e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit GATA PF00320.22 EDP45119.1 - 2.4e-10 39.5 5.7 1.9e-06 27.1 1.0 2.6 2 0 0 2 2 2 2 GATA zinc finger OrfB_Zn_ribbon PF07282.6 EDP45119.1 - 0.85 9.3 4.3 9.2 6.0 3.0 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.1 EDP45119.1 - 2.6 7.7 6.3 5.4 6.6 0.2 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Ctf8 PF09696.5 EDP45120.1 - 1.6e-16 60.1 0.0 3.2e-10 39.8 0.0 2.5 2 1 0 2 2 2 2 Ctf8 NUDE_C PF04880.8 EDP45120.1 - 3 8.1 13.1 18 5.6 9.1 2.0 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region GHMP_kinases_N PF00288.21 EDP45122.1 - 1.7e-09 37.6 1.0 3.4e-09 36.6 0.7 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDP45122.1 - 5.3e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_31 PF13560.1 EDP45122.1 - 0.15 12.2 2.2 7.3 6.8 0.2 3.1 4 0 0 4 4 4 0 Helix-turn-helix domain HCMV_UL139 PF12507.3 EDP45123.1 - 0.0084 16.2 1.4 0.026 14.6 1.0 1.8 1 0 0 1 1 1 1 Human Cytomegalovirus UL139 protein Myb_DNA-bind_6 PF13921.1 EDP45123.1 - 0.044 13.8 1.8 0.061 13.4 0.2 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDP45123.1 - 0.089 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DFP PF04127.10 EDP45124.1 - 2e-19 69.9 0.0 4.2e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein zf-H2C2_2 PF13465.1 EDP45125.1 - 9.1e-09 35.1 12.7 9.8e-09 35.0 0.4 4.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDP45125.1 - 9.4e-08 31.9 13.6 3e-06 27.2 0.2 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EDP45125.1 - 5.2e-05 23.0 2.5 0.36 10.8 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EDP45125.1 - 0.00025 21.1 10.5 0.00039 20.5 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EDP45125.1 - 0.0091 16.1 2.3 3.9 7.8 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF3861 PF12977.2 EDP45125.1 - 0.065 13.3 0.1 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) Complex1_LYR PF05347.10 EDP45126.1 - 8.2e-14 51.1 1.2 1.4e-13 50.3 0.7 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDP45126.1 - 8.9e-12 45.0 0.8 1.2e-11 44.6 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EDP45126.1 - 0.00056 20.3 0.4 0.00072 19.9 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like adh_short_C2 PF13561.1 EDP45127.1 - 2.2e-13 50.5 0.0 3.9e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDP45127.1 - 2.1e-12 47.2 0.1 5.9e-12 45.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase DnaJ PF00226.26 EDP45128.1 - 2.2e-19 68.9 4.7 3.5e-19 68.2 3.2 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 EDP45128.1 - 0.0025 17.4 0.7 0.0053 16.3 0.5 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EDP45128.1 - 0.0028 17.1 8.1 0.0046 16.4 5.6 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 EDP45128.1 - 0.0064 16.5 6.0 0.0091 16.1 4.2 1.2 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 EDP45128.1 - 0.041 13.5 12.5 0.24 11.1 0.6 2.2 1 1 1 2 2 2 0 Glycine zipper 2TM domain CoA_binding_3 PF13727.1 EDP45128.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain Gly-zipper_Omp PF13488.1 EDP45128.1 - 0.3 10.7 12.5 0.56 9.8 8.7 1.4 1 1 0 1 1 1 0 Glycine zipper DUF2404 PF10296.4 EDP45129.1 - 9.5e-07 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SPRY PF00622.23 EDP45130.1 - 1.2e-07 31.7 0.0 3.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 SPRY domain DUF4532 PF15046.1 EDP45130.1 - 0.017 14.1 1.6 0.026 13.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) SUI1 PF01253.17 EDP45131.1 - 8.5e-14 51.1 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cgr1 PF03879.9 EDP45131.1 - 0.002 18.3 5.8 0.003 17.7 4.0 1.2 1 0 0 1 1 1 1 Cgr1 family DUF1366 PF07104.6 EDP45131.1 - 0.079 12.5 0.9 0.14 11.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Toxin_43 PF15604.1 EDP45131.1 - 0.26 11.3 4.3 0.4 10.7 3.0 1.2 1 0 0 1 1 1 0 Putative toxin 43 Gtr1_RagA PF04670.7 EDP45132.1 - 6.8e-34 117.0 0.3 5.7e-18 64.9 0.1 3.2 3 0 0 3 3 3 3 Gtr1/RagA G protein conserved region Arf PF00025.16 EDP45132.1 - 0.011 14.9 0.2 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family EF_TS PF00889.14 EDP45133.1 - 3.5e-16 59.2 0.0 1.8e-15 56.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor TS Nucleoporin_C PF03177.9 EDP45134.1 - 2e-71 241.2 0.7 3.4e-71 240.5 0.5 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDP45134.1 - 5.2e-41 140.7 0.0 7.1e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Mito_carr PF00153.22 EDP45135.1 - 2.4e-41 139.3 0.4 2.3e-15 56.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein LCM PF04072.9 EDP45136.1 - 1.1e-19 70.7 0.0 9.5e-19 67.6 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Fcf1 PF04900.7 EDP45137.1 - 1.2e-22 79.8 0.5 1.1e-20 73.6 0.1 2.5 2 1 0 2 2 2 1 Fcf1 SE PF08491.5 EDP45138.1 - 1.5e-84 283.0 0.0 1.3e-83 280.0 0.0 2.2 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EDP45138.1 - 1.2e-12 47.4 0.5 7e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDP45138.1 - 1.8e-10 40.4 1.4 3e-09 36.4 1.0 2.3 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EDP45138.1 - 6.9e-08 31.7 0.0 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EDP45138.1 - 0.0003 20.7 0.3 0.00069 19.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDP45138.1 - 0.0011 18.0 0.2 0.0048 16.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EDP45138.1 - 0.0011 17.9 1.0 0.09 11.6 0.2 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EDP45138.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EDP45138.1 - 0.0037 16.9 0.1 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EDP45138.1 - 0.0039 15.8 0.1 0.88 8.1 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.11 EDP45138.1 - 0.0061 16.0 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EDP45138.1 - 0.0066 16.3 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EDP45138.1 - 0.0093 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 EDP45138.1 - 0.012 14.4 3.6 0.02 13.7 0.5 2.3 3 0 0 3 3 3 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EDP45138.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EDP45138.1 - 0.025 12.8 0.0 0.04 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EDP45138.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EDP45138.1 - 0.051 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EDP45138.1 - 0.053 13.5 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 EDP45138.1 - 0.055 13.8 0.1 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EDP45138.1 - 0.061 13.3 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EDP45138.1 - 0.17 10.2 0.1 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GMC_oxred_N PF00732.14 EDP45138.1 - 0.2 10.7 0.3 16 4.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_oxidored PF12831.2 EDP45138.1 - 0.45 9.5 2.6 0.68 8.9 1.8 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase ATP-synt_J PF04911.7 EDP45139.1 - 8.8e-22 76.3 0.3 1e-21 76.1 0.2 1.1 1 0 0 1 1 1 1 ATP synthase j chain AMP-binding PF00501.23 EDP45140.1 - 7e-67 225.6 0.0 1.7e-66 224.3 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Clathrin PF00637.15 EDP45141.1 - 5.9e-20 71.3 0.6 1.9e-11 43.7 0.1 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 EDP45141.1 - 0.00078 19.1 5.0 0.0017 18.0 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDP45141.1 - 0.0011 18.7 8.5 0.0074 16.1 6.2 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP45141.1 - 0.0015 18.4 6.5 0.0039 17.1 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 EDP45141.1 - 0.004 17.3 0.6 0.012 15.7 0.4 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 VPS11_C PF12451.3 EDP45141.1 - 0.0068 16.2 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-rbx1 PF12678.2 EDP45141.1 - 0.021 14.9 3.3 0.047 13.8 2.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDP45141.1 - 0.033 13.8 3.3 0.11 12.1 2.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDP45141.1 - 0.84 9.3 5.8 2.2 8.0 4.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDP45141.1 - 3.5 7.2 5.8 9.5 5.8 4.0 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MRI PF15325.1 EDP45142.1 - 0.17 12.8 1.0 0.4 11.6 0.7 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection SpoIIIAH PF12685.2 EDP45143.1 - 0.02 14.3 2.1 0.03 13.8 1.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Totivirus_coat PF05518.6 EDP45143.1 - 3.7 5.2 7.2 5.6 4.6 5.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein PAT1 PF09770.4 EDP45143.1 - 4 5.5 12.3 4.9 5.2 8.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1075 PF06388.6 EDP45144.1 - 0.016 14.8 1.9 0.028 14.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DNA_pol_viral_N PF00242.12 EDP45144.1 - 7.8 5.4 9.1 10 5.0 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ras PF00071.17 EDP45145.1 - 2.9e-10 39.7 0.1 3.5e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Ras family ATP-synt_10 PF05176.9 EDP45146.1 - 1.8e-33 115.9 0.0 2e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein U3_assoc_6 PF08640.6 EDP45147.1 - 5.9e-16 57.9 2.2 2.1e-15 56.2 1.5 1.9 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 DUF2818 PF10993.3 EDP45147.1 - 0.067 13.6 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) DNA_primase_lrg PF04104.9 EDP45148.1 - 5.2e-76 255.3 0.0 1.1e-75 254.2 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit PIP5K PF01504.13 EDP45149.1 - 1.3e-78 263.6 0.0 1.9e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Nop14 PF04147.7 EDP45150.1 - 0.013 13.5 4.8 0.015 13.2 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EDP45150.1 - 0.033 13.9 6.6 0.043 13.5 4.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lysis_col PF02402.11 EDP45150.1 - 0.48 10.0 4.4 1.1 8.9 0.8 2.3 2 0 0 2 2 2 0 Lysis protein Sigma70_ner PF04546.8 EDP45150.1 - 6.3 6.3 12.6 5.5 6.5 7.7 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region His_biosynth PF00977.16 EDP45151.1 - 8.2e-40 136.4 0.0 8.9e-19 67.6 0.0 3.7 3 1 0 3 3 3 3 Histidine biosynthesis protein GATase PF00117.23 EDP45151.1 - 1.4e-16 60.4 0.0 4.1e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EDP45151.1 - 2.7e-06 27.0 0.1 2.4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EDP45151.1 - 0.00088 18.7 0.3 0.085 12.2 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 SNO PF01174.14 EDP45151.1 - 0.013 15.0 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 0 SNO glutamine amidotransferase family PhoD PF09423.5 EDP45152.1 - 6.8e-40 136.9 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase DUF629 PF04780.7 EDP45152.1 - 0.2 10.1 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Ribosomal_S7 PF00177.16 EDP45153.1 - 4.2e-32 110.7 0.0 5.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HATPase_c PF02518.21 EDP45154.1 - 1.4e-18 66.6 0.1 3.2e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDP45154.1 - 1.9e-15 56.6 0.0 1.1e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EDP45154.1 - 8.2e-13 48.3 0.0 2.9e-08 33.7 0.0 2.8 1 1 1 2 2 2 2 Response regulator receiver domain GAF_2 PF13185.1 EDP45154.1 - 0.0061 17.0 0.0 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 GAF domain ELFV_dehydrog PF00208.16 EDP45154.1 - 0.045 13.3 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Imm31 PF15595.1 EDP45154.1 - 0.2 11.4 0.0 0.52 10.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 31 zf-C2H2 PF00096.21 EDP45155.1 - 5.6e-12 45.2 7.8 5.4e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP45155.1 - 1.5e-09 37.4 8.5 0.00018 21.6 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDP45155.1 - 3.4e-09 36.5 7.8 6.4e-06 26.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDP45155.1 - 2.9e-06 27.2 0.2 0.058 13.5 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDP45155.1 - 2.1e-05 24.2 1.2 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDP45155.1 - 0.0012 19.0 1.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EDP45155.1 - 0.031 14.3 0.8 0.052 13.6 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EDP45155.1 - 0.25 11.4 1.4 7.9 6.6 0.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EDP45155.1 - 3.3 7.4 8.3 8.6 6.1 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TFIIB PF00382.14 EDP45156.1 - 1.1e-11 44.3 0.5 2e-11 43.5 0.3 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Nup84_Nup100 PF04121.8 EDP45157.1 - 9.3e-93 311.1 0.0 2e-92 310.1 0.0 1.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Brix PF04427.13 EDP45158.1 - 2.9e-42 144.5 0.0 4.3e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EDP45158.1 - 0.0016 16.5 22.0 0.0021 16.1 15.3 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EDP45158.1 - 0.097 11.1 18.2 0.14 10.6 12.6 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EDP45158.1 - 0.12 11.6 8.3 0.16 11.1 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 EDP45158.1 - 0.51 9.4 18.0 0.83 8.7 12.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 EDP45158.1 - 2.4 7.0 7.9 4.6 6.1 5.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.7 EDP45158.1 - 6.1 6.4 21.7 12 5.5 15.1 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FCH PF00611.18 EDP45159.1 - 1.3e-20 73.3 3.0 1.8e-20 72.8 0.3 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EDP45159.1 - 3e-11 42.5 0.0 5.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDP45159.1 - 4.6e-09 35.7 0.0 8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDP45159.1 - 3.5e-08 32.8 0.0 7.6e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Streptin-Immun PF11083.3 EDP45159.1 - 0.017 15.0 1.4 0.12 12.4 0.1 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF2315 PF10231.4 EDP45159.1 - 2.1 8.2 6.9 0.54 10.1 0.9 2.4 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) CorA PF01544.13 EDP45160.1 - 6.7e-12 45.0 6.3 0.00039 19.5 0.0 3.2 2 1 0 3 3 3 3 CorA-like Mg2+ transporter protein PCNA_C PF02747.10 EDP45161.1 - 4.1e-41 139.8 0.6 2.7e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EDP45161.1 - 7.2e-30 103.1 0.3 3e-29 101.1 0.3 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EDP45161.1 - 0.0021 16.8 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EDP45161.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad9 RTA1 PF04479.8 EDP45162.1 - 1.8e-41 142.1 0.8 2.5e-41 141.6 0.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Cyclin PF08613.6 EDP45163.1 - 9.8e-14 52.0 0.0 1.5e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDP45163.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SET PF00856.23 EDP45164.1 - 5.1e-05 23.6 0.0 0.012 15.8 0.0 2.6 2 0 0 2 2 2 2 SET domain Peptidase_S8 PF00082.17 EDP45165.1 - 8.2e-48 162.9 0.0 2.5e-47 161.3 0.0 1.8 2 1 0 2 2 2 1 Subtilase family TPPII PF12580.3 EDP45165.1 - 5.9e-41 139.9 0.0 9.6e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II FBA PF04300.8 EDP45165.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 F-box associated region GDI PF00996.13 EDP45166.1 - 5e-49 166.7 0.0 1.3e-48 165.4 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor Peptidase_S49 PF01343.13 EDP45167.1 - 3.8e-42 143.6 0.1 4.4e-27 94.7 0.2 3.2 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 EDP45167.1 - 6.4e-07 29.2 0.4 5.9e-05 22.8 0.3 2.8 3 0 0 3 3 3 2 Clp protease DPBB_1 PF03330.13 EDP45168.1 - 4.2e-12 45.8 0.0 7.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDP45168.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Barwin family DUF2217 PF10265.4 EDP45168.1 - 0.35 9.5 2.2 0.41 9.3 1.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Phosphoprotein PF00922.12 EDP45168.1 - 1.2 8.3 5.5 1.4 8.0 3.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Macoilin PF09726.4 EDP45168.1 - 2.5 6.2 6.7 2.9 6.0 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein TRAM_LAG1_CLN8 PF03798.11 EDP45169.1 - 2.3e-32 112.1 27.2 2.3e-32 112.1 18.8 2.8 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EDP45169.1 - 5e-05 22.7 0.0 5e-05 22.7 0.0 3.9 3 1 1 4 4 4 1 TRAM1-like protein Archaeal_AmoA PF12942.2 EDP45169.1 - 0.026 14.3 0.2 0.026 14.3 0.1 2.1 2 1 1 3 3 3 0 Archaeal ammonia monooxygenase subunit A (AmoA) E1-E2_ATPase PF00122.15 EDP45169.1 - 0.16 10.9 5.2 0.27 10.2 0.0 2.4 2 0 0 2 2 2 0 E1-E2 ATPase DUF2839 PF10999.3 EDP45169.1 - 1.7 8.7 8.0 1.7 8.7 1.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Aldedh PF00171.17 EDP45170.1 - 2.5e-10 39.2 1.0 8.7e-10 37.5 0.7 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family XPG_I PF00867.13 EDP45172.1 - 3.5e-11 43.0 0.1 6.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDP45172.1 - 1.6e-08 34.6 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.4 EDP45172.1 - 0.066 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EDP45172.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain SKN1 PF03935.10 EDP45173.1 - 8.7e-169 561.8 6.8 1.2e-168 561.3 4.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 EDP45174.1 - 3.5e-171 569.7 4.9 4.7e-171 569.3 3.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EDP45174.1 - 0.00069 18.9 0.0 0.0048 16.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DNA_pol_B_exo2 PF10108.4 EDP45174.1 - 0.075 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB zf-C2H2 PF00096.21 EDP45175.1 - 3.7e-13 48.9 15.2 1.7e-05 24.8 0.5 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP45175.1 - 7.3e-11 41.6 17.3 0.00061 19.9 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDP45175.1 - 1.8e-07 31.1 8.4 0.09 13.1 0.2 4.4 3 1 0 3 3 3 3 Zinc-finger double domain zinc_ribbon_5 PF13719.1 EDP45175.1 - 0.035 13.6 1.4 7.2 6.2 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EDP45175.1 - 0.11 12.4 5.4 0.39 10.6 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.1 EDP45175.1 - 0.43 10.3 4.6 8.4 6.1 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.16 EDP45175.1 - 7.5 6.5 8.8 3.1 7.7 1.6 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-C2HC_2 PF13913.1 EDP45175.1 - 9 6.0 15.5 0.18 11.4 0.7 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type SET PF00856.23 EDP45176.1 - 1.6e-13 51.2 0.0 6.5e-13 49.2 0.0 2.0 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EDP45176.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding TFIIA PF03153.8 EDP45176.1 - 0.082 12.7 13.8 0.14 12.0 9.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EDP45176.1 - 0.21 9.4 20.4 0.29 9.0 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EDP45176.1 - 1.1 8.4 12.2 1.7 7.7 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 EDP45176.1 - 3.3 7.0 15.9 6.1 6.1 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 EDP45176.1 - 3.5 6.0 20.5 5.2 5.4 14.2 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EDP45176.1 - 3.5 5.5 15.0 4.9 5.0 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EDP45176.1 - 6.6 5.9 19.9 11 5.2 13.8 1.2 1 0 0 1 1 1 0 SDA1 Steroid_dh PF02544.11 EDP45177.1 - 1.5e-38 131.9 0.5 1.5e-38 131.9 0.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EDP45177.1 - 1.4e-05 24.4 0.2 2.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EDP45177.1 - 0.0012 18.9 0.9 0.0012 18.9 0.6 2.3 2 2 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EDP45177.1 - 0.018 15.2 1.8 0.021 15.0 0.4 1.8 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CLASP_N PF12348.3 EDP45178.1 - 1.7e-19 70.1 0.0 2.4e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 EDP45178.1 - 0.00064 19.9 0.7 0.0018 18.5 0.3 2.0 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EDP45178.1 - 0.00082 19.2 2.0 0.0011 18.8 0.0 2.3 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EDP45178.1 - 0.0026 18.2 1.1 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 HEAT-like repeat Skp1_POZ PF03931.10 EDP45179.1 - 5.6e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain ATP-synt_C PF00137.16 EDP45182.1 - 3.5e-27 94.0 28.4 5.6e-17 61.3 6.1 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 EDP45182.1 - 0.14 11.7 4.8 0.13 11.8 1.4 2.4 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Peptidase_C13 PF01650.13 EDP45183.1 - 2.5e-45 154.8 0.0 3.1e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DS PF01916.12 EDP45184.1 - 1.7e-129 431.2 0.0 2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase ThiF PF00899.16 EDP45185.1 - 3e-37 127.4 0.1 8.1e-37 126.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EDP45185.1 - 1.2e-23 82.4 0.3 2.2e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDP45185.1 - 1.4e-17 62.8 3.1 2.8e-17 61.7 2.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EDP45185.1 - 0.0017 18.4 0.0 0.0048 16.9 0.0 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EDP45185.1 - 0.0064 16.0 0.4 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain ApbA PF02558.11 EDP45185.1 - 0.018 14.5 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EDP45185.1 - 0.027 14.8 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_3 PF13920.1 EDP45185.1 - 0.04 13.5 3.0 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DAO PF01266.19 EDP45185.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EDP45185.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ecm33 PF12454.3 EDP45185.1 - 0.12 12.2 2.1 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein G-patch PF01585.18 EDP45187.1 - 3.3e-13 49.2 0.4 3.3e-13 49.2 0.3 2.1 2 0 0 2 2 2 1 G-patch domain R3H PF01424.17 EDP45187.1 - 1.1e-11 44.2 0.0 2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EDP45187.1 - 6.7e-06 25.8 0.2 1.3e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 DExH-box splicing factor binding site SIR2 PF02146.12 EDP45189.1 - 9.5e-20 71.0 0.0 2.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EDP45189.1 - 3.5e-05 23.4 0.2 0.00013 21.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF592) CutC PF03932.9 EDP45189.1 - 0.056 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 CutC family DUF1769 PF08588.5 EDP45190.1 - 6.1e-16 58.1 0.5 1.3e-15 57.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SURF6 PF04935.7 EDP45191.1 - 5.9e-22 78.0 28.3 8.8e-22 77.4 19.6 1.2 1 0 0 1 1 1 1 Surfeit locus protein 6 Fmp27_SW PF10305.4 EDP45191.1 - 6.6 7.2 9.1 1.1 9.7 2.8 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain WD40 PF00400.27 EDP45192.1 - 2.3e-92 299.8 18.4 1.3e-13 50.2 0.0 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EDP45192.1 - 2.6e-05 24.0 0.0 0.00093 18.9 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDP45192.1 - 0.00057 18.1 8.6 0.39 8.7 0.0 4.6 3 1 1 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EDP45192.1 - 0.0007 18.7 0.4 4.3 6.3 0.0 3.6 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal NLE PF08154.7 EDP45192.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.7 EDP45192.1 - 0.0027 15.6 0.9 0.01 13.7 0.0 1.9 2 0 0 2 2 2 1 IKI3 family Nucleoporin_N PF08801.6 EDP45192.1 - 0.064 12.0 0.8 4.8 5.8 0.1 2.5 2 1 0 2 2 2 0 Nup133 N terminal like UQ_con PF00179.21 EDP45193.1 - 5.3e-40 136.0 0.1 7e-20 70.8 0.2 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme BRO1 PF03097.13 EDP45195.1 - 3.1e-44 151.2 0.4 3.1e-44 151.2 0.3 2.5 1 1 2 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDP45195.1 - 1.1e-23 83.6 10.2 1.2e-23 83.5 5.5 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF1178 PF06676.6 EDP45195.1 - 0.06 13.5 1.3 0.16 12.1 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) SlyX PF04102.7 EDP45195.1 - 3.4 8.0 8.7 2.5 8.5 0.3 4.3 4 0 0 4 4 4 0 SlyX WGG PF10273.4 EDP45196.1 - 4e-21 74.8 0.0 6.3e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 adh_short PF00106.20 EDP45197.1 - 8.6e-28 97.3 3.5 1.1e-27 96.9 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDP45197.1 - 3.7e-15 56.3 0.2 4.7e-15 56.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDP45197.1 - 9.3e-09 35.2 1.2 1.3e-08 34.7 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDP45197.1 - 0.00054 19.4 0.5 0.00093 18.6 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDP45197.1 - 0.0042 17.0 2.2 0.024 14.6 0.6 2.2 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDP45197.1 - 0.0048 16.6 0.4 0.011 15.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EDP45197.1 - 0.0069 16.0 0.6 0.011 15.3 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EDP45197.1 - 0.04 13.0 0.1 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain COG4 PF08318.7 EDP45198.1 - 1.1e-34 119.6 0.1 2.3e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 COG4 transport protein OHCU_decarbox PF09349.5 EDP45199.1 - 5.4e-05 23.5 0.0 0.093 13.0 0.0 2.7 1 1 1 2 2 2 2 OHCU decarboxylase Fork_head PF00250.13 EDP45200.1 - 5.7e-10 39.1 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain APS_kinase PF01583.15 EDP45201.1 - 3.4e-70 234.7 0.0 4e-70 234.4 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EDP45201.1 - 2.4e-07 30.6 0.0 3.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP45201.1 - 1.7e-05 25.1 0.0 6.3e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP45201.1 - 7e-05 23.6 0.0 0.00011 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDP45201.1 - 0.00016 20.9 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EDP45201.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EDP45201.1 - 0.0076 15.3 0.0 0.15 11.1 0.0 2.1 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EDP45201.1 - 0.023 14.1 0.1 0.84 8.9 0.0 2.1 1 1 1 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 EDP45201.1 - 0.067 13.4 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EDP45201.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain SHNi-TPR PF10516.4 EDP45202.1 - 7.6e-08 31.4 0.1 3.1e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EDP45202.1 - 0.054 13.4 1.9 6.3 6.8 0.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat La PF05383.12 EDP45204.1 - 1.2e-17 63.4 0.2 2.1e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 La domain PhoPQ_related PF10142.4 EDP45206.1 - 0.00013 20.6 0.5 0.00018 20.1 0.4 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein EURL PF06937.6 EDP45206.1 - 0.0089 15.4 10.1 0.011 15.1 7.0 1.1 1 0 0 1 1 1 1 EURL protein DUF4559 PF15112.1 EDP45206.1 - 0.02 14.0 10.7 0.026 13.6 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) AIP3 PF03915.8 EDP45206.1 - 0.022 13.6 12.2 0.028 13.3 8.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 APG6 PF04111.7 EDP45206.1 - 0.037 13.0 12.0 0.057 12.4 8.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 EDP45206.1 - 0.08 12.1 12.5 0.11 11.7 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Myosin_tail_1 PF01576.14 EDP45206.1 - 0.1 10.3 16.9 0.18 9.5 11.5 1.4 1 1 0 1 1 1 0 Myosin tail GAS PF13851.1 EDP45206.1 - 0.19 10.8 17.4 0.25 10.5 4.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 EDP45206.1 - 0.27 11.0 8.6 0.6 9.9 3.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EDP45206.1 - 0.37 9.9 5.5 0.76 8.8 3.4 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EDP45206.1 - 0.43 9.4 10.5 0.57 9.0 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EDP45206.1 - 0.63 9.8 6.9 0.45 10.3 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.8 EDP45206.1 - 0.87 9.3 4.2 0.55 10.0 1.6 1.8 2 0 0 2 2 1 0 PEP-utilising enzyme, N-terminal HAUS6_N PF14661.1 EDP45206.1 - 0.94 8.7 8.8 1.3 8.3 6.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.8 EDP45206.1 - 0.94 8.4 6.6 1.1 8.2 4.2 1.4 1 1 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 EDP45206.1 - 1.1 7.0 5.1 1.2 6.8 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HisKA_3 PF07730.8 EDP45206.1 - 1.1 9.7 4.4 1.1 9.6 0.5 2.6 1 1 1 2 2 2 0 Histidine kinase ATG16 PF08614.6 EDP45206.1 - 1.4 8.6 18.8 2.5 7.8 12.4 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 EDP45206.1 - 1.5 8.9 11.0 1.3 9.0 3.2 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 EDP45206.1 - 1.6 8.5 16.9 0.24 11.1 6.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 EDP45206.1 - 1.7 9.0 10.1 0.55 10.6 1.9 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Peptidase_C6 PF00851.13 EDP45206.1 - 2.1 6.8 7.5 2.5 6.6 5.2 1.1 1 0 0 1 1 1 0 Helper component proteinase YlqD PF11068.3 EDP45206.1 - 2.8 8.0 17.0 0.6 10.1 5.8 2.3 1 1 1 2 2 2 0 YlqD protein DUF4359 PF14271.1 EDP45206.1 - 4 7.8 6.6 6.7 7.1 1.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) FCH PF00611.18 EDP45206.1 - 4.4 7.5 11.4 1.2 9.3 0.3 2.6 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Cortex-I_coil PF09304.5 EDP45206.1 - 5.3 7.1 17.0 2.2 8.3 6.0 2.7 1 1 2 3 3 3 0 Cortexillin I, coiled coil Nsp1_C PF05064.8 EDP45206.1 - 5.4 6.6 12.9 7.9 6.1 3.1 2.8 1 1 2 3 3 3 0 Nsp1-like C-terminal region DUF972 PF06156.8 EDP45206.1 - 7.6 6.9 10.9 40 4.6 1.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EDP45206.1 - 8.5 6.7 9.9 1.4 9.2 0.6 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein BRAP2 PF07576.7 EDP45207.1 - 5.9e-15 54.7 0.0 1.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 EDP45207.1 - 2.3e-09 36.9 10.8 4.8e-09 35.8 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 EDP45207.1 - 2e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EDP45207.1 - 3.7e-05 23.6 9.4 8.4e-05 22.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDP45207.1 - 0.00013 21.9 4.5 0.00013 21.9 3.1 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDP45207.1 - 0.00015 21.3 8.5 0.00015 21.3 5.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP45207.1 - 0.00044 19.9 8.7 0.00044 19.9 6.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDP45207.1 - 0.00069 19.2 8.1 0.00069 19.2 5.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDP45207.1 - 0.0055 16.5 6.8 0.0055 16.5 4.7 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDP45207.1 - 0.0063 16.0 5.9 0.0063 16.0 4.1 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EDP45207.1 - 0.014 15.2 1.6 0.031 14.0 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EDP45207.1 - 0.043 13.7 5.7 0.26 11.2 4.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDP45207.1 - 0.06 13.0 4.4 0.078 12.7 1.5 2.2 1 1 1 2 2 2 0 RING-type zinc-finger RRM_1 PF00076.17 EDP45207.1 - 0.089 12.4 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TerY-C PF15616.1 EDP45207.1 - 1.5 8.7 7.9 0.38 10.6 2.3 2.1 1 1 1 2 2 2 0 TerY-C metal binding domain Pkinase PF00069.20 EDP45208.1 - 3e-40 138.0 0.0 1.4e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45208.1 - 3.3e-24 85.3 0.0 4.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45208.1 - 0.00036 19.5 0.0 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA PF00004.24 EDP45209.1 - 4e-96 318.2 0.0 9e-47 158.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDP45209.1 - 5.7e-16 58.2 0.2 2e-15 56.4 0.1 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EDP45209.1 - 1.1e-13 50.7 0.1 1.2e-05 24.4 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDP45209.1 - 1e-12 48.2 0.0 2.3e-07 30.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EDP45209.1 - 1.3e-12 47.8 0.0 1.9e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDP45209.1 - 2.3e-12 46.8 0.4 5.6e-06 26.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDP45209.1 - 8.1e-11 42.1 0.2 0.0043 17.1 0.0 4.0 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.12 EDP45209.1 - 8.6e-11 41.3 0.0 1.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 EDP45209.1 - 9.6e-11 42.5 0.0 0.00087 20.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDP45209.1 - 5.1e-10 39.6 0.0 0.00096 19.1 0.0 3.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 EDP45209.1 - 2.3e-09 36.9 3.2 0.0043 16.4 0.0 4.6 3 2 1 4 4 4 2 AAA domain TIP49 PF06068.8 EDP45209.1 - 3e-09 36.0 0.1 0.0012 17.6 0.0 2.5 2 1 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EDP45209.1 - 9.6e-09 34.9 0.0 0.001 18.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDP45209.1 - 6.7e-08 32.1 1.5 0.0028 17.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 EDP45209.1 - 1e-07 31.2 0.0 0.0072 15.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EDP45209.1 - 2.4e-07 30.7 0.0 0.0067 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EDP45209.1 - 3.6e-07 29.5 0.4 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EDP45209.1 - 1.1e-06 27.9 1.0 0.47 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 EDP45209.1 - 1.4e-06 28.4 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Parvo_NS1 PF01057.12 EDP45209.1 - 4.2e-06 25.8 0.1 0.0046 15.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 EDP45209.1 - 4.5e-06 26.9 0.0 0.058 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EDP45209.1 - 6.8e-06 26.4 0.0 0.04 14.2 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EDP45209.1 - 6.9e-06 26.1 0.1 0.14 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EDP45209.1 - 7.2e-06 25.9 0.0 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EDP45209.1 - 1.5e-05 24.4 0.0 0.38 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EDP45209.1 - 1.8e-05 24.0 0.1 0.17 11.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EDP45209.1 - 1.9e-05 24.7 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EDP45209.1 - 2.5e-05 23.9 0.0 0.11 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 EDP45209.1 - 6.8e-05 21.9 0.0 0.021 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EDP45209.1 - 0.00011 21.9 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 EDP45209.1 - 0.00017 21.3 0.0 2 8.0 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 EDP45209.1 - 0.00022 20.8 0.0 0.69 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EDP45209.1 - 0.00023 20.8 0.0 0.44 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EDP45209.1 - 0.00027 20.6 0.1 0.5 10.0 0.0 3.6 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 EDP45209.1 - 0.00028 20.6 0.1 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF2075 PF09848.4 EDP45209.1 - 0.00067 18.7 0.0 0.3 10.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EDP45209.1 - 0.00069 19.2 0.0 0.97 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EDP45209.1 - 0.0049 15.7 0.1 0.48 9.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EDP45209.1 - 0.0052 16.5 0.3 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EDP45209.1 - 0.0066 16.0 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EDP45209.1 - 0.012 14.5 0.0 0.33 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EDP45209.1 - 0.012 15.0 1.1 6.5 6.0 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain IPT PF01745.11 EDP45209.1 - 0.031 13.4 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EDP45209.1 - 0.033 13.1 0.0 0.6 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 EDP45209.1 - 0.038 13.6 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EDP45209.1 - 0.065 12.4 0.0 8 5.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DEAD PF00270.24 EDP45209.1 - 0.12 11.8 0.3 62 3.0 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase PIF1 PF05970.9 EDP45209.1 - 0.13 11.1 0.0 8.9 5.1 0.0 3.1 3 0 0 3 3 3 0 PIF1-like helicase Zot PF05707.7 EDP45209.1 - 0.14 11.5 0.2 24 4.3 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DUF3508 PF12018.3 EDP45210.1 - 0.02 13.9 1.0 0.11 11.4 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3508) PI-PLC-X PF00388.14 EDP45211.1 - 6.9e-05 22.2 0.1 0.00022 20.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HSP70 PF00012.15 EDP45212.1 - 1e-152 509.1 0.0 4.6e-152 507.0 0.0 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDP45212.1 - 3.1e-10 39.1 0.0 5.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Ribosomal_L30_N PF08079.7 EDP45213.1 - 9.2e-26 89.6 14.0 1.9e-25 88.6 9.7 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EDP45213.1 - 3.9e-20 71.1 0.4 1.2e-19 69.6 0.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PGC7_Stella PF15549.1 EDP45213.1 - 1.3 8.9 4.8 2.2 8.2 3.3 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain PX PF00787.19 EDP45214.1 - 5.1e-21 74.5 0.3 7.4e-21 74.0 0.2 1.2 1 0 0 1 1 1 1 PX domain FA_hydroxylase PF04116.8 EDP45215.1 - 2.8e-14 53.4 16.6 2.8e-14 53.4 11.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily SIR2 PF02146.12 EDP45217.1 - 6.3e-55 185.6 0.0 1.2e-54 184.7 0.0 1.4 2 0 0 2 2 2 1 Sir2 family A_deamin PF02137.13 EDP45218.1 - 9.9e-46 156.6 0.0 1.2e-45 156.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain zf-CCHC PF00098.18 EDP45219.1 - 2.6e-13 49.2 22.0 0.00023 20.9 0.3 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EDP45219.1 - 5.4e-07 29.1 21.1 0.048 13.3 1.0 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EDP45219.1 - 5.7e-07 28.9 13.4 0.00019 20.8 0.2 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 EDP45219.1 - 0.14 11.9 15.9 1.4 8.7 0.7 3.6 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDP45219.1 - 0.44 10.2 12.9 0.76 9.5 1.2 3.5 3 0 0 3 3 3 0 Zinc knuckle V-SNARE_C PF12352.3 EDP45220.1 - 9.1e-14 51.2 1.7 1.8e-13 50.3 1.2 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EDP45220.1 - 0.0004 20.0 0.1 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 Sec20 Syntaxin-18_N PF10496.4 EDP45220.1 - 0.022 14.5 0.5 0.06 13.2 0.0 2.0 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Methyltransf_31 PF13847.1 EDP45221.1 - 3.1e-12 46.3 0.1 4.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDP45221.1 - 3.4e-11 42.8 0.1 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EDP45221.1 - 5.9e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP45221.1 - 7.2e-10 39.4 0.0 1.6e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP45221.1 - 6.3e-09 36.2 0.0 1.6e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EDP45221.1 - 1.3e-07 30.9 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EDP45221.1 - 4.2e-07 30.0 0.0 7.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDP45221.1 - 4.2e-07 29.3 0.1 5.6e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EDP45221.1 - 2.2e-06 27.1 0.2 3.8e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EDP45221.1 - 4.6e-06 25.5 0.1 7.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EDP45221.1 - 4.8e-06 26.9 0.0 9.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDP45221.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EDP45221.1 - 0.0003 21.1 0.0 0.00056 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDP45221.1 - 0.0004 19.9 0.1 0.00066 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EDP45221.1 - 0.0038 16.6 0.1 0.0055 16.1 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 EDP45221.1 - 0.03 15.1 0.0 0.065 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EDP45221.1 - 0.039 13.5 0.6 0.062 12.8 0.2 1.4 1 1 0 1 1 1 0 Met-10+ like-protein TehB PF03848.9 EDP45221.1 - 0.047 12.8 0.6 0.14 11.3 0.4 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EDP45221.1 - 0.058 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EDP45221.1 - 0.066 12.3 0.1 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDP45221.1 - 0.1 11.6 0.1 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 EDP45221.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Oxidored_q6 PF01058.17 EDP45222.1 - 3.9e-22 78.2 0.0 4.5e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 EDP45223.1 - 1.2e-63 214.7 0.0 1.6e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45223.1 - 4.6e-42 143.8 0.0 7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45223.1 - 1.5e-06 27.4 0.0 2.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDP45223.1 - 0.34 9.9 0.0 0.61 9.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CTP_transf_1 PF01148.15 EDP45224.1 - 1.2e-73 248.0 20.0 2e-73 247.2 13.9 1.4 1 0 0 1 1 1 1 Cytidylyltransferase family Acyl-CoA_dh_C PF12806.2 EDP45225.1 - 0.051 13.4 2.4 0.49 10.2 0.1 2.4 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Pkinase PF00069.20 EDP45226.1 - 4.9e-59 199.6 0.0 2.6e-41 141.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45226.1 - 1.7e-25 89.5 0.0 2e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDP45226.1 - 1.2e-05 24.4 0.1 5.9e-05 22.1 0.0 2.0 2 1 0 3 3 3 1 Kinase-like APH PF01636.18 EDP45226.1 - 0.00026 20.8 0.0 0.0037 17.0 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Response_reg PF00072.19 EDP45226.1 - 0.00034 20.5 1.4 0.00075 19.4 0.5 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EDP45226.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 EDP45226.1 - 0.046 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EDP45226.1 - 0.056 12.2 0.1 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EDP45226.1 - 0.14 11.1 0.0 0.47 9.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 EDP45227.1 - 9.4e-38 129.8 50.8 9.4e-38 129.8 35.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDP45227.1 - 1.3e-14 53.6 8.9 1.3e-14 53.6 6.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EDP45227.1 - 4.1e-07 28.6 16.3 5.6e-07 28.1 10.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CIAPIN1 PF05093.8 EDP45228.1 - 1.3e-30 105.3 2.9 2.2e-30 104.7 1.7 1.6 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SICA_beta PF12878.2 EDP45228.1 - 0.039 13.7 0.5 0.069 12.9 0.4 1.3 1 0 0 1 1 1 0 SICA extracellular beta domain Calc_CGRP_IAPP PF00214.14 EDP45228.1 - 0.096 12.7 0.6 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family PRCC PF10253.4 EDP45229.1 - 1.2e-07 32.5 18.9 4.2e-06 27.5 13.1 2.8 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting EMP24_GP25L PF01105.19 EDP45230.1 - 3.4e-20 72.5 0.0 3.4e-20 72.5 0.0 1.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.13 EDP45231.1 - 1.1e-50 170.7 1.8 1.5e-50 170.3 1.3 1.1 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 EDP45231.1 - 0.00096 18.7 0.5 0.0016 18.0 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 EDP45231.1 - 0.001 18.7 0.2 0.0066 16.1 0.2 2.0 1 1 0 1 1 1 1 WH1 domain Glyco_hydro_2 PF00703.16 EDP45231.1 - 0.024 15.0 1.8 1.8 9.0 0.1 2.4 2 1 0 2 2 2 0 Glycosyl hydrolases family 2 FAM60A PF15396.1 EDP45231.1 - 4.5 6.9 7.2 2.9 7.5 2.6 1.9 1 1 1 2 2 2 0 Protein Family FAM60A Tau95 PF09734.4 EDP45232.1 - 1.7e-33 116.2 0.4 2.5e-33 115.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Pol_alpha_B_N PF08418.5 EDP45233.1 - 2.7e-13 50.0 0.0 3.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Nop PF01798.13 EDP45234.1 - 9.2e-57 190.5 0.2 1.8e-56 189.5 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDP45234.1 - 2.9e-27 94.2 0.1 5.2e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDP45234.1 - 2.3e-13 50.0 0.2 2.3e-13 50.0 0.1 2.4 2 0 0 2 2 1 1 NOP5NT (NUC127) domain Nop14 PF04147.7 EDP45234.1 - 0.0091 13.9 22.2 0.013 13.4 15.4 1.2 1 0 0 1 1 1 1 Nop14-like family GAGA_bind PF06217.7 EDP45234.1 - 0.082 12.8 12.3 0.11 12.3 8.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EDP45234.1 - 0.22 11.1 43.5 0.53 9.9 30.1 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EDP45234.1 - 0.4 10.4 9.8 0.93 9.2 6.8 1.8 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EDP45234.1 - 0.86 9.4 23.2 0.29 11.0 14.0 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SET PF00856.23 EDP45234.1 - 5.1 7.3 9.0 41 4.4 0.0 2.3 2 0 0 2 2 2 0 SET domain Herpes_DNAp_acc PF04929.7 EDP45234.1 - 5.8 5.7 15.7 9.3 5.1 10.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zip PF02535.17 EDP45234.1 - 9.6 5.1 6.4 14 4.5 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Rhodanese PF00581.15 EDP45235.1 - 7.6e-14 52.0 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain PS_Dcarbxylase PF02666.10 EDP45237.1 - 4.4e-73 244.8 0.0 3.1e-71 238.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Nup88 PF10168.4 EDP45238.1 - 5.3e-19 67.5 5.0 7.1e-11 40.6 0.0 2.9 2 1 0 2 2 2 2 Nuclear pore component FYVE PF01363.16 EDP45239.1 - 1.4e-19 69.6 7.7 1.4e-19 69.6 5.4 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EDP45239.1 - 1.7e-10 40.5 5.6 1.7e-10 40.5 3.9 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP45239.1 - 0.00051 20.0 5.8 0.00051 20.0 4.0 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP45239.1 - 0.0096 15.6 26.9 0.024 14.3 3.7 3.7 4 0 0 4 4 4 2 zinc-RING finger domain zf-rbx1 PF12678.2 EDP45239.1 - 0.022 14.8 6.8 0.022 14.8 4.7 3.4 3 2 0 3 3 3 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDP45239.1 - 0.028 14.1 2.2 0.028 14.1 1.5 2.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EDP45239.1 - 0.41 10.3 23.8 0.1 12.2 3.6 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EDP45239.1 - 2.2 8.1 17.7 0.19 11.6 4.6 2.8 3 1 0 3 3 3 0 FYVE-type zinc finger zf-DHHC PF01529.15 EDP45239.1 - 2.9 7.2 7.3 0.71 9.2 2.3 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C2HC5 PF06221.8 EDP45239.1 - 8.3 6.2 10.9 6.4 6.6 2.5 3.2 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type Ribosomal_L29e PF01779.12 EDP45240.1 - 2.9e-14 52.6 1.2 7.1e-12 44.9 0.2 2.2 2 0 0 2 2 2 2 Ribosomal L29e protein family Dimer_Tnp_hAT PF05699.9 EDP45240.1 - 0.12 12.0 0.1 0.15 11.6 0.1 1.4 1 1 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2404 PF10296.4 EDP45241.1 - 0.038 14.1 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) TAP_C PF03943.8 EDP45243.1 - 9e-13 47.4 0.0 1.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EDP45243.1 - 4.1e-08 32.6 0.9 5.4e-06 25.9 0.5 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EDP45243.1 - 7.1e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 EDP45243.1 - 2e-05 24.9 0.1 0.00011 22.4 0.1 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 EDP45243.1 - 0.00057 19.5 0.8 0.074 12.8 0.3 2.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 EDP45243.1 - 0.0045 16.9 1.5 3.1 8.4 0.1 3.9 3 0 0 3 3 3 1 Leucine rich repeat UBA_4 PF14555.1 EDP45243.1 - 0.098 12.2 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain MOR2-PAG1_N PF14222.1 EDP45244.1 - 4e-87 293.1 0.0 1.8e-86 291.0 0.0 2.0 1 1 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EDP45244.1 - 8.2e-36 124.0 0.5 8.2e-36 124.0 0.3 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EDP45244.1 - 4e-08 31.3 1.3 7.7e-05 20.4 0.0 2.3 2 0 0 2 2 2 2 Cell morphogenesis central region NAD_binding_4 PF07993.7 EDP45245.1 - 1.4e-52 178.0 0.1 1.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EDP45245.1 - 3.8e-07 29.0 0.0 5.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDP45245.1 - 3.5e-05 23.3 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EDP45246.1 - 9.9e-78 261.3 0.0 1.3e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EDP45246.1 - 1.6e-14 53.8 0.1 5.7e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDP45246.1 - 8.5e-09 36.2 0.2 1.2e-07 32.5 0.0 3.2 4 1 0 4 4 4 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 EDP45246.1 - 1.8e-05 23.7 0.0 4.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Condensation domain DUF2717 PF10911.3 EDP45247.1 - 0.061 12.8 0.1 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) DUF1935 PF09149.5 EDP45247.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) lci PF12197.3 EDP45247.1 - 2.7 7.6 6.1 1 8.9 0.2 2.3 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein COX6B PF02297.12 EDP45248.1 - 2.1e-23 82.1 1.0 4.2e-23 81.1 0.7 1.5 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 EDP45248.1 - 0.2 11.4 2.4 4.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) XAP5 PF04921.9 EDP45249.1 - 1.9e-76 256.7 8.4 2.6e-76 256.3 5.9 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF2058 PF09831.4 EDP45249.1 - 1.6 8.5 9.4 1.9 8.3 2.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Sua5_yciO_yrdC PF01300.13 EDP45250.1 - 8.3e-51 171.7 0.0 1.4e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EDP45250.1 - 1.5e-29 102.6 0.0 2.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pkinase PF00069.20 EDP45251.1 - 5.5e-68 228.9 0.0 7.8e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45251.1 - 1.5e-31 109.4 0.0 1.8e-30 105.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDP45251.1 - 2e-05 24.0 0.3 3.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EDP45251.1 - 0.00013 21.0 0.1 0.052 12.5 0.0 3.2 3 1 0 3 3 3 1 Kinase-like APH PF01636.18 EDP45251.1 - 0.0023 17.7 0.8 0.41 10.3 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDP45251.1 - 0.013 14.8 0.2 0.3 10.3 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EDP45251.1 - 0.067 12.2 0.4 0.2 10.7 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BCDHK_Adom3 PF10436.4 EDP45253.1 - 3.2e-28 98.3 2.6 4e-27 94.7 2.2 2.0 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDP45253.1 - 1.1e-07 31.5 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3636 PF12331.3 EDP45253.1 - 0.017 14.7 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) SNARE PF05739.14 EDP45254.1 - 0.0005 19.7 4.8 0.0016 18.0 3.3 1.9 1 0 0 1 1 1 1 SNARE domain HIGH_NTase1 PF05636.6 EDP45254.1 - 0.021 13.8 1.9 0.036 13.1 0.2 1.8 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase DUF2150 PF09920.4 EDP45254.1 - 0.088 12.3 2.8 0.21 11.1 0.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) ISG65-75 PF11727.3 EDP45254.1 - 0.16 10.9 6.2 0.048 12.6 2.1 1.6 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF3347 PF11827.3 EDP45254.1 - 0.82 9.6 9.4 0.2 11.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Tropomyosin_1 PF12718.2 EDP45254.1 - 0.91 9.3 12.2 0.18 11.6 5.9 1.6 2 0 0 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EDP45254.1 - 1.1 9.1 11.2 1.2 8.9 4.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2203 PF09969.4 EDP45254.1 - 2.5 8.3 6.4 4.8 7.4 1.5 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1451 PF07295.6 EDP45254.1 - 3.4 7.4 6.9 0.74 9.5 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) WBS_methylT PF12589.3 EDP45255.1 - 3.2e-17 62.7 9.2 1.4e-12 47.8 1.8 2.4 2 0 0 2 2 2 2 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EDP45255.1 - 8e-10 39.0 0.0 1.7e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP45255.1 - 1.7e-08 34.3 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDP45255.1 - 7.2e-06 26.3 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDP45255.1 - 2.3e-05 24.0 0.0 4.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP45255.1 - 7.2e-05 23.1 0.0 0.00042 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP45255.1 - 0.00012 22.6 0.1 0.0002 21.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP45255.1 - 0.0025 17.8 0.0 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EDP45255.1 - 0.0079 15.7 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 DNA methylase AdoMet_MTase PF07757.8 EDP45255.1 - 0.037 14.1 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Atg14 PF10186.4 EDP45255.1 - 0.047 12.6 1.1 0.065 12.1 0.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PCMT PF01135.14 EDP45255.1 - 0.098 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EDP45255.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1980 PF09323.5 EDP45256.1 - 0.048 13.4 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EST1 PF10374.4 EDP45256.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 TPR_11 PF13414.1 EDP45257.1 - 2.4e-13 49.5 15.4 6.5e-05 22.4 0.3 8.7 8 1 1 9 9 9 3 TPR repeat TPR_2 PF07719.12 EDP45257.1 - 1.2e-12 46.7 12.2 0.19 11.7 0.0 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDP45257.1 - 1.3e-11 43.5 9.0 0.027 14.0 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDP45257.1 - 1.3e-10 41.6 19.9 0.0091 16.6 0.3 7.8 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDP45257.1 - 7.5e-10 38.6 19.2 0.00037 20.3 0.1 6.9 6 1 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDP45257.1 - 2.7e-09 36.8 26.2 1.1 10.0 0.2 11.0 10 2 3 13 13 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDP45257.1 - 7.2e-09 35.5 16.8 0.61 10.6 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDP45257.1 - 1.8e-08 33.5 7.6 0.45 10.4 0.0 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDP45257.1 - 2.6e-08 34.0 22.6 3.1e-05 24.2 1.1 7.4 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDP45257.1 - 8.7e-05 22.0 10.0 2.7 8.0 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDP45257.1 - 0.00016 21.4 12.0 0.86 9.4 1.0 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_5 PF12688.2 EDP45257.1 - 0.0019 18.2 0.9 0.32 11.0 0.2 3.7 4 0 0 4 4 4 1 Tetratrico peptide repeat TPR_17 PF13431.1 EDP45257.1 - 0.0038 17.3 4.1 34 4.9 0.0 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EDP45257.1 - 0.016 13.9 2.1 0.023 13.3 0.3 2.0 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.1 EDP45257.1 - 1.1 9.2 16.7 0.44 10.5 0.2 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Hist_deacetyl PF00850.14 EDP45258.1 - 1.6e-76 257.5 0.0 2.2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Acid_PPase PF12689.2 EDP45259.1 - 2.3e-15 56.6 0.0 2.3e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Pex2_Pex12 PF04757.9 EDP45260.1 - 1.6e-34 119.3 11.3 2.3e-34 118.8 7.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region RIX1 PF08167.7 EDP45261.1 - 5.5e-12 45.6 0.3 1.5e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.6 EDP45262.1 - 1.9e-218 727.1 0.0 2.3e-218 726.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 MbeD_MobD PF04899.7 EDP45262.1 - 0.64 9.9 4.0 30 4.6 1.1 3.5 3 0 0 3 3 3 0 MbeD/MobD like HK PF02110.10 EDP45264.1 - 7.2e-70 234.9 0.3 3.3e-66 222.9 0.4 2.1 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EDP45264.1 - 6.4e-40 136.1 0.0 1.4e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI PfkB PF00294.19 EDP45264.1 - 0.0034 16.5 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDP45264.1 - 0.0036 16.5 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RNA_pol_Rpb4 PF03874.11 EDP45265.1 - 7.8e-23 80.7 0.1 1.2e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 HCO3_cotransp PF00955.16 EDP45266.1 - 9.8e-46 156.4 18.6 4e-27 95.0 2.4 3.1 2 1 1 3 3 3 3 HCO3- transporter family Peptidase_M20 PF01546.23 EDP45267.1 - 4.4e-23 81.7 0.0 7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDP45267.1 - 2.8e-11 43.1 0.0 6.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EDP45267.1 - 0.0016 18.1 0.0 0.0066 16.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 DUF4392 PF14336.1 EDP45267.1 - 0.18 10.6 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Myosin_tail_1 PF01576.14 EDP45268.1 - 0.00014 19.7 12.9 0.00029 18.7 8.9 1.4 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 EDP45268.1 - 0.011 14.2 1.6 0.019 13.4 1.1 1.3 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.6 EDP45268.1 - 0.019 13.2 16.1 0.0045 15.3 7.0 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.6 EDP45268.1 - 0.032 12.9 13.5 0.11 11.1 9.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EDP45268.1 - 0.11 11.9 6.8 0.19 11.0 4.3 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EDP45268.1 - 0.12 10.7 3.0 0.19 10.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EDP45268.1 - 0.83 7.4 2.4 2 6.2 1.7 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eRF1_1 PF03463.10 EDP45269.1 - 8.4e-44 148.3 0.1 1.7e-43 147.3 0.0 1.5 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.10 EDP45269.1 - 1.4e-18 67.1 0.0 2.6e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EDP45269.1 - 7.1e-18 65.2 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 AD PF09793.4 EDP45270.1 - 4.3e-14 52.1 0.0 7.8e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain CactinC_cactus PF09732.4 EDP45271.1 - 8.5e-52 173.9 1.6 1.8e-51 172.9 1.1 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EDP45271.1 - 6.3e-51 172.3 0.7 1.4e-50 171.2 0.5 1.6 1 0 0 1 1 1 1 Conserved mid region of cactin DUF3840 PF12944.2 EDP45271.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) DUF2072 PF09845.4 EDP45271.1 - 0.55 10.1 3.9 1.8 8.4 2.7 1.9 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF4407 PF14362.1 EDP45271.1 - 2.4 7.0 15.0 0.18 10.7 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DnaJ_CXXCXGXG PF00684.14 EDP45272.1 - 0.021 14.8 0.4 0.04 13.9 0.3 1.5 1 0 0 1 1 1 0 DnaJ central domain Prim_Zn_Ribbon PF08273.7 EDP45272.1 - 0.086 12.9 4.7 0.87 9.7 0.7 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Amidohydro_2 PF04909.9 EDP45273.1 - 3.3e-10 39.9 0.7 5.9e-10 39.1 0.5 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EDP45273.1 - 0.0012 18.9 4.5 0.0038 17.2 3.1 1.8 1 1 0 1 1 1 1 Amidohydrolase ICMT PF04140.9 EDP45274.1 - 1.8e-24 85.7 0.5 3.1e-24 85.0 0.4 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EDP45274.1 - 9.5e-13 48.1 1.3 1.7e-12 47.3 0.9 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EDP45274.1 - 0.00017 21.0 0.9 0.00019 20.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EDP45274.1 - 0.00057 18.5 0.1 0.00085 17.9 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 EDP45274.1 - 0.032 13.5 9.0 0.057 12.7 6.2 1.5 1 1 0 1 1 1 0 NnrU protein Kinesin PF00225.18 EDP45275.1 - 1.7e-79 266.9 0.5 2.3e-79 266.5 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain PRAI PF00697.17 EDP45275.1 - 0.0089 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF904 PF06005.7 EDP45275.1 - 0.027 14.7 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Lectin_N PF03954.9 EDP45275.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain CCDC144C PF14915.1 EDP45275.1 - 0.23 10.3 1.7 0.37 9.6 1.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Nup160 PF11715.3 EDP45276.1 - 3.2e-39 134.4 0.3 8e-39 133.1 0.2 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF508 PF04370.7 EDP45276.1 - 0.23 11.0 3.5 0.2 11.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) IPPT PF01715.12 EDP45276.1 - 0.28 10.1 0.0 0.47 9.4 0.0 1.2 1 0 0 1 1 1 0 IPP transferase JAB PF01398.16 EDP45277.1 - 1.1e-35 121.7 0.0 2.2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDP45277.1 - 3.8e-28 97.8 1.0 3.8e-28 97.8 0.7 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EDP45277.1 - 2.3e-09 36.7 0.0 3.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MbeB_N PF04837.7 EDP45277.1 - 0.045 13.8 0.3 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 MbeB-like, N-term conserved region UPF0172 PF03665.8 EDP45277.1 - 0.064 12.7 0.1 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Hist_deacetyl PF00850.14 EDP45281.1 - 1.4e-82 277.4 0.2 2e-82 276.9 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EDP45281.1 - 1.6e-06 27.7 0.0 1.7e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Arb2 domain DEP PF00610.16 EDP45282.1 - 0.00035 20.2 0.1 0.063 13.0 0.0 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDV3 PF15359.1 EDP45282.1 - 0.02 14.9 2.8 0.046 13.8 1.9 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 G10 PF01125.12 EDP45283.1 - 4.2e-46 156.0 0.6 4.8e-46 155.9 0.4 1.1 1 0 0 1 1 1 1 G10 protein Lum_binding PF00677.12 EDP45284.1 - 7.7e-28 96.2 0.0 2.5e-17 62.5 0.0 3.8 2 1 0 2 2 2 2 Lumazine binding domain LRR_4 PF12799.2 EDP45285.1 - 1.8e-33 113.5 0.0 1.4e-05 24.5 0.0 7.9 7 2 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDP45285.1 - 3e-24 84.5 8.5 1.4e-05 24.7 0.4 8.0 6 2 2 9 9 9 5 Leucine rich repeat LRR_7 PF13504.1 EDP45285.1 - 8.3e-10 37.2 13.1 3.6 8.2 0.0 11.0 13 0 0 13 13 13 2 Leucine rich repeat LRR_1 PF00560.28 EDP45285.1 - 1.9e-08 33.1 21.2 0.58 10.4 0.0 12.4 12 3 1 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.1 EDP45285.1 - 1.4e-07 30.8 1.5 14 6.1 0.0 8.3 9 1 1 10 10 10 2 Leucine Rich repeat LRR_9 PF14580.1 EDP45285.1 - 0.0029 17.2 0.4 1.3 8.5 0.0 3.2 1 1 2 3 3 3 1 Leucine-rich repeat MAP65_ASE1 PF03999.7 EDP45286.1 - 3.4e-45 154.7 9.8 8.5e-44 150.1 1.9 2.6 2 2 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Vps52 PF04129.7 EDP45287.1 - 7.9e-33 113.7 0.4 1e-30 106.7 0.1 2.8 2 1 0 2 2 2 1 Vps52 / Sac2 family Spc7 PF08317.6 EDP45287.1 - 0.01 14.5 0.3 0.016 13.8 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG6 PF06419.6 EDP45287.1 - 0.013 13.6 0.0 0.019 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 CENP-F_leu_zip PF10473.4 EDP45287.1 - 0.028 14.2 0.2 0.06 13.1 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EDP45287.1 - 0.035 13.8 0.3 0.86 9.3 0.2 2.5 2 0 0 2 2 2 0 Laminin Domain II ADIP PF11559.3 EDP45287.1 - 0.15 11.9 3.4 0.31 10.9 2.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EDP45287.1 - 0.16 11.7 0.3 0.32 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IPK PF03770.11 EDP45288.1 - 3.3e-30 105.2 0.0 4.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase zf-H2C2_2 PF13465.1 EDP45289.1 - 2.4e-35 119.1 37.7 3.4e-09 36.5 0.6 6.8 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 EDP45289.1 - 1.5e-26 91.0 37.1 4.5e-06 26.6 2.0 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP45289.1 - 8.2e-19 66.5 37.2 0.00041 20.4 1.6 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDP45289.1 - 5.6e-09 35.8 12.8 0.0004 20.4 0.2 5.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDP45289.1 - 7.5e-08 32.0 21.5 0.0003 20.5 0.3 5.5 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDP45289.1 - 0.0031 17.5 0.9 0.0031 17.5 0.7 3.6 2 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EDP45289.1 - 0.027 14.6 17.7 0.26 11.5 0.6 4.9 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EDP45289.1 - 0.1 12.3 18.3 0.12 12.0 0.8 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EDP45289.1 - 0.1 12.7 22.7 0.11 12.5 1.4 4.1 2 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EDP45289.1 - 0.14 11.8 5.9 3.4 7.5 0.5 3.1 2 1 0 2 2 2 0 BED zinc finger zf-RING_3 PF14369.1 EDP45289.1 - 0.4 10.7 11.8 2.9 7.9 0.2 4.1 3 1 0 3 3 3 0 zinc-finger Rep_fac-A_C PF08646.5 EDP45289.1 - 0.46 10.1 5.6 6.3 6.5 0.2 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Zn-ribbon_8 PF09723.5 EDP45289.1 - 0.9 9.5 16.8 5.6 7.0 0.3 4.7 3 2 1 4 4 4 0 Zinc ribbon domain C1_4 PF07975.7 EDP45289.1 - 1.8 8.5 12.1 5.7 7.0 1.0 3.7 2 1 1 3 3 3 0 TFIIH C1-like domain DUF164 PF02591.10 EDP45289.1 - 2.6 7.9 4.8 6.9 6.5 0.1 2.8 3 0 0 3 3 3 0 Putative zinc ribbon domain RPAP2_Rtr1 PF04181.8 EDP45289.1 - 2.8 8.1 19.4 1.3 9.1 0.7 4.6 2 1 2 4 4 4 0 Rtr1/RPAP2 family DUF2225 PF09986.4 EDP45289.1 - 2.9 7.3 9.2 1.8 7.9 0.5 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_4 PF13717.1 EDP45289.1 - 3.2 7.5 10.1 4.5 7.0 0.4 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDP45289.1 - 4.3 7.0 10.8 5.1 6.7 0.6 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Lipase_3 PF01764.20 EDP45290.1 - 5.5e-16 58.4 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 EDP45290.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EDP45290.1 - 0.086 12.6 0.0 0.31 10.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDP45290.1 - 0.21 11.4 6.9 0.087 12.6 0.2 3.2 3 1 0 3 3 3 0 Alpha/beta hydrolase family Ribosomal_S13_N PF08069.7 EDP45291.1 - 2.4e-29 100.9 0.6 3.9e-29 100.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EDP45291.1 - 1.8e-21 75.6 0.1 2.9e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EDP45291.1 - 0.00025 20.7 0.2 0.001 18.7 0.0 1.9 1 1 0 2 2 2 1 'Paired box' domain Ribosomal_S6e PF01092.14 EDP45292.1 - 1.1e-55 186.6 0.1 2e-55 185.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Sbi-IV PF11621.3 EDP45292.1 - 0.052 13.7 2.1 0.11 12.6 1.4 1.6 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI AATase PF07247.7 EDP45293.1 - 0.051 12.1 0.0 0.16 10.4 0.0 1.8 2 0 0 2 2 2 0 Alcohol acetyltransferase Pkinase PF00069.20 EDP45294.1 - 1e-40 139.5 0.0 8.6e-28 97.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45294.1 - 4.3e-19 68.5 0.0 1.8e-12 46.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase SNF2_N PF00176.18 EDP45295.1 - 4.2e-70 235.9 0.0 6.3e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDP45295.1 - 8.4e-06 25.5 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EDP45295.1 - 0.00043 19.9 7.2 0.001 18.7 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDP45295.1 - 0.005 16.6 9.4 0.014 15.1 6.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDP45295.1 - 0.0056 16.6 8.4 0.015 15.3 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EDP45295.1 - 0.0065 16.3 0.0 0.12 12.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EDP45295.1 - 0.0081 15.7 8.2 0.019 14.5 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 EDP45295.1 - 0.014 15.2 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 HIRAN domain Rad50_zn_hook PF04423.9 EDP45295.1 - 0.05 13.0 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif FYVE PF01363.16 EDP45295.1 - 0.39 10.6 5.9 0.28 11.1 2.1 2.2 2 0 0 2 2 2 0 FYVE zinc finger Peptidase_S10 PF00450.17 EDP45296.1 - 1.5e-103 347.2 0.0 1.8e-103 346.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDP45296.1 - 0.0079 16.0 0.4 0.21 11.4 0.3 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Xpo1 PF08389.7 EDP45297.1 - 0.041 13.7 0.0 0.48 10.3 0.0 2.9 2 0 0 2 2 2 0 Exportin 1-like protein TRAM_LAG1_CLN8 PF03798.11 EDP45298.1 - 0.17 11.3 3.3 0.25 10.8 2.3 1.2 1 0 0 1 1 1 0 TLC domain HA PF03457.9 EDP45298.1 - 5.3 7.2 6.7 8.3 6.5 0.0 3.4 2 1 0 3 3 3 0 Helicase associated domain TFIIA PF03153.8 EDP45299.1 - 1.3 8.8 4.8 1.9 8.3 3.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.21 EDP45300.1 - 6.5e-25 87.1 0.0 1.3e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-Sec23_Sec24 PF04810.10 EDP45300.1 - 0.14 11.7 0.3 0.4 10.2 0.1 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF4544 PF15077.1 EDP45300.1 - 0.37 10.2 2.4 0.63 9.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) PMSR PF01625.16 EDP45301.1 - 6.2e-54 182.0 0.1 7.4e-54 181.8 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HbrB PF08539.6 EDP45302.1 - 4.8e-20 71.9 0.0 3.9e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 HbrB-like ApbA_C PF08546.6 EDP45303.1 - 1.4e-20 73.5 0.0 2.4e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDP45303.1 - 0.00097 18.6 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Nol1_Nop2_Fmu PF01189.12 EDP45304.1 - 2.3e-18 66.5 0.0 5.2e-17 62.1 0.0 2.8 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EDP45304.1 - 1.2e-05 25.3 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDP45304.1 - 0.00018 21.5 0.0 0.00044 20.2 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EDP45304.1 - 0.035 13.5 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Bin3 PF06859.7 EDP45304.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 EDP45304.1 - 0.16 12.5 0.0 1.4 9.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain BcrAD_BadFG PF01869.15 EDP45305.1 - 5e-25 88.3 0.4 5.8e-25 88.1 0.3 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.8 EDP45305.1 - 0.1 12.1 0.5 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region RhoGEF PF00621.15 EDP45306.1 - 5.8e-23 81.6 0.0 1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EDP45306.1 - 1.3e-05 25.3 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EDP45306.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain ERM PF00769.14 EDP45306.1 - 0.25 10.8 3.7 0.62 9.5 2.6 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Adap_comp_sub PF00928.16 EDP45307.1 - 3.5e-90 301.6 0.1 4.8e-90 301.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDP45307.1 - 2.5e-07 30.4 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LisH PF08513.6 EDP45308.1 - 0.0096 15.6 0.2 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 LisH FLO_LFY PF01698.11 EDP45309.1 - 0.56 8.9 8.4 1.2 7.9 5.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Ribosomal_L18e PF00828.14 EDP45310.1 - 3.2e-16 59.8 1.4 5.9e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 EDP45311.1 - 2.2e-17 62.4 0.0 3.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP45311.1 - 1.4e-14 53.7 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP45311.1 - 3e-12 46.1 0.0 5.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 EDP45311.1 - 2.3 7.5 6.3 3.1 7.1 4.3 1.2 1 0 0 1 1 1 0 Vta1 like Iso_dh PF00180.15 EDP45312.1 - 4.5e-100 334.9 0.0 5.2e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 EDP45313.1 - 2.7e-81 273.2 0.0 3e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cupin_8 PF13621.1 EDP45314.1 - 2.2e-30 105.9 0.1 3.4e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EDP45314.1 - 0.0012 18.1 0.1 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EDP45314.1 - 0.0043 17.2 0.7 0.45 10.7 0.0 2.5 1 1 1 2 2 2 2 JmjC domain, hydroxylase Histone PF00125.19 EDP45315.1 - 5.3e-27 93.7 0.0 6.8e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDP45315.1 - 3e-05 23.9 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDP45316.1 - 9.8e-23 80.0 0.4 1.4e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDP45316.1 - 7.1e-07 29.1 0.1 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDP45316.1 - 0.00041 20.5 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EDP45316.1 - 0.01 16.3 0.2 0.014 15.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EDP45316.1 - 0.033 13.6 0.1 0.059 12.8 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3530 PF12048.3 EDP45316.1 - 0.044 12.7 1.4 0.052 12.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Bt_P21 PF05560.6 EDP45316.1 - 0.075 12.4 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Snf7 PF03357.16 EDP45317.1 - 9.8e-11 41.3 7.9 1.2e-10 41.0 5.4 1.0 1 0 0 1 1 1 1 Snf7 HrpB7 PF09486.5 EDP45317.1 - 0.0015 18.5 3.7 0.0019 18.1 2.6 1.0 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) LUC7 PF03194.10 EDP45317.1 - 0.002 17.7 2.1 0.0024 17.4 1.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF342 PF03961.8 EDP45317.1 - 0.13 10.6 0.9 0.15 10.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Calpain_III PF01067.17 EDP45317.1 - 0.14 11.7 0.9 0.17 11.4 0.6 1.1 1 0 0 1 1 1 0 Calpain large subunit, domain III IMD PF08397.6 EDP45317.1 - 0.19 11.0 2.7 0.23 10.7 1.9 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Mnd1 PF03962.10 EDP45317.1 - 0.24 11.0 3.0 0.37 10.4 2.1 1.3 1 0 0 1 1 1 0 Mnd1 family TMF_TATA_bd PF12325.3 EDP45317.1 - 0.28 10.9 6.3 0.13 11.9 2.6 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding H-kinase_dim PF02895.9 EDP45317.1 - 0.75 10.1 4.0 3 8.2 0.1 2.2 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Snapin_Pallidin PF14712.1 EDP45317.1 - 1.3 9.3 6.8 0.96 9.7 2.0 2.0 1 1 1 2 2 2 0 Snapin/Pallidin CCDC155 PF14662.1 EDP45317.1 - 1.5 8.3 8.1 2.3 7.7 2.0 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 PspA_IM30 PF04012.7 EDP45317.1 - 1.5 8.0 9.1 4.6 6.5 6.3 1.6 1 1 0 1 1 1 0 PspA/IM30 family Cluap1 PF10234.4 EDP45317.1 - 1.7 7.8 6.7 0.68 9.0 1.2 1.9 1 1 1 2 2 2 0 Clusterin-associated protein-1 Cyclin_N PF00134.18 EDP45318.1 - 0.0075 15.8 0.0 0.08 12.5 0.0 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain Tfb4 PF03850.9 EDP45319.1 - 5.7e-30 104.5 0.0 7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Staphylcoagulse PF04022.7 EDP45319.1 - 0.41 10.0 2.1 0.48 9.8 0.7 1.8 2 0 0 2 2 2 0 Staphylocoagulase repeat Pkinase PF00069.20 EDP45320.1 - 3e-39 134.7 0.0 3.2e-26 92.0 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45320.1 - 3.9e-19 68.7 0.0 7.9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45320.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like p450 PF00067.17 EDP45321.1 - 4.8e-51 173.7 0.0 6.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Duo1 PF08651.5 EDP45321.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 Glucan_synthase PF02364.10 EDP45322.1 - 3.1e-300 997.8 0.0 6e-300 996.9 0.0 1.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDP45322.1 - 9.5e-37 125.4 0.0 2.2e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.10 EDP45323.1 - 1.6e-51 175.1 0.1 1.6e-51 175.1 0.1 1.8 2 0 0 2 2 2 1 1,3-beta-glucan synthase component KilA-N PF04383.8 EDP45324.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain LIM PF00412.17 EDP45325.1 - 1.1e-16 60.6 11.7 4.1e-10 39.5 2.3 2.5 2 0 0 2 2 2 2 LIM domain DZR PF12773.2 EDP45325.1 - 5.6 6.8 9.1 1.9e+02 1.9 6.3 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 EDP45326.1 - 8.9e-07 28.9 11.8 0.0016 18.6 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDP45326.1 - 9.1e-07 28.7 8.2 0.00075 19.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger CCAP PF11105.3 EDP45326.1 - 0.0021 17.8 0.3 0.0041 16.8 0.2 1.5 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a zf-H2C2_2 PF13465.1 EDP45326.1 - 0.047 13.9 11.5 0.87 9.9 1.7 2.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EDP45326.1 - 1.5 9.1 5.0 32 4.8 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1762 PF08574.5 EDP45327.1 - 7.3e-08 32.7 1.5 8.7e-08 32.4 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) Rhomboid PF01694.17 EDP45328.1 - 9.8e-28 97.0 13.1 9.8e-28 97.0 9.1 1.9 1 1 0 1 1 1 1 Rhomboid family DUF457 PF04307.9 EDP45328.1 - 0.0048 16.2 1.2 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF4203 PF13886.1 EDP45328.1 - 0.0085 15.5 21.0 0.012 15.0 4.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4203) Phage_holin_1 PF04531.8 EDP45328.1 - 3 7.9 5.7 40 4.3 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage holin PQ-loop PF04193.9 EDP45329.1 - 1.5e-38 130.1 10.8 6.1e-20 70.5 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EDP45329.1 - 0.014 15.2 6.2 0.22 11.3 0.3 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange HEM4 PF02602.10 EDP45330.1 - 4.3e-24 85.0 0.0 6.7e-23 81.1 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Citrate_synt PF00285.16 EDP45331.1 - 5.5e-96 321.4 0.0 6.9e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EDP45331.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone PLDc PF00614.17 EDP45332.1 - 7.5e-11 41.4 0.1 0.00027 20.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EDP45332.1 - 2.5e-10 40.1 0.0 7.4e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EDP45332.1 - 1e-07 31.7 0.4 2.1e-07 30.6 0.3 1.6 1 0 0 1 1 1 1 PX domain PH PF00169.24 EDP45332.1 - 3.2e-05 24.0 0.3 6.2e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 PH domain AAA PF00004.24 EDP45333.1 - 3.6e-41 140.4 0.0 6.9e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDP45333.1 - 7.8e-27 92.9 0.0 1.8e-25 88.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EDP45333.1 - 3.2e-07 30.1 0.8 9.3e-07 28.6 0.5 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EDP45333.1 - 1.8e-06 28.8 0.2 7.4e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDP45333.1 - 2.4e-06 27.7 0.8 0.00046 20.3 0.1 3.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDP45333.1 - 3.4e-06 26.8 0.0 1.1e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDP45333.1 - 2.8e-05 23.9 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDP45333.1 - 4.2e-05 23.0 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDP45333.1 - 7.6e-05 21.8 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDP45333.1 - 0.00011 22.0 0.6 0.0007 19.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EDP45333.1 - 0.00069 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EDP45333.1 - 0.0012 18.3 0.0 0.061 12.7 0.0 2.6 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EDP45333.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EDP45333.1 - 0.0023 16.8 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EDP45333.1 - 0.0028 17.8 0.4 0.012 15.7 0.0 2.4 3 0 0 3 3 1 1 RNA helicase AAA_18 PF13238.1 EDP45333.1 - 0.0034 17.6 0.2 0.061 13.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP45333.1 - 0.0048 16.9 0.0 0.0048 16.9 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 EDP45333.1 - 0.0074 15.7 8.7 0.044 13.1 0.1 3.4 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.16 EDP45333.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EDP45333.1 - 0.018 14.1 2.1 1.5 7.8 0.0 2.7 2 1 1 3 3 3 0 KaiC NB-ARC PF00931.17 EDP45333.1 - 0.024 13.4 0.1 0.47 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EDP45333.1 - 0.028 14.0 0.2 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EDP45333.1 - 0.036 14.1 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EDP45333.1 - 0.059 12.8 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EDP45333.1 - 0.06 12.5 0.0 0.16 11.1 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EDP45333.1 - 0.07 12.8 4.6 0.075 12.7 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 EDP45333.1 - 0.075 13.3 0.2 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.1 EDP45333.1 - 0.079 12.9 0.0 0.079 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 EDP45333.1 - 0.079 12.6 0.0 0.96 9.0 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Torsin PF06309.6 EDP45333.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_29 PF13555.1 EDP45333.1 - 0.12 11.8 3.4 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.7 EDP45333.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.7 EDP45333.1 - 1.7 8.2 3.6 1.7 8.2 0.0 2.5 2 1 1 3 3 2 0 NACHT domain Zeta_toxin PF06414.7 EDP45333.1 - 9.7 5.2 8.4 1.7 7.7 0.0 2.7 2 1 1 3 3 2 0 Zeta toxin Xpo1 PF08389.7 EDP45334.1 - 1.3e-23 83.6 0.0 5.1e-23 81.6 0.0 2.1 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 EDP45334.1 - 1.2e-05 25.1 0.6 3.2e-05 23.7 0.4 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain ParcG PF10274.4 EDP45334.1 - 0.01 15.7 0.0 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein Pkinase PF00069.20 EDP45335.1 - 7.5e-67 225.2 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45335.1 - 8.6e-44 149.5 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45335.1 - 5e-10 38.8 0.0 8.8e-07 28.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 EDP45335.1 - 0.0098 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kdo PF06293.9 EDP45335.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDP45335.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDP45335.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RA PF00788.18 EDP45335.1 - 0.11 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain UQ_con PF00179.21 EDP45336.1 - 2.5e-40 137.1 0.0 2.7e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EDP45336.1 - 0.0058 16.3 0.1 0.0091 15.6 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EDP45336.1 - 0.023 14.5 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.6 EDP45336.1 - 0.036 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ras PF00071.17 EDP45337.1 - 3.6e-62 208.5 0.1 4.3e-62 208.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP45337.1 - 5e-21 75.4 0.0 7.1e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP45337.1 - 9.4e-13 47.7 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDP45337.1 - 1.5e-06 28.1 0.1 2e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDP45337.1 - 3.9e-05 23.8 0.0 0.00011 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EDP45337.1 - 5.6e-05 22.6 0.1 0.00031 20.2 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDP45337.1 - 0.00034 19.8 0.1 0.00071 18.7 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EDP45337.1 - 0.0031 16.6 0.0 0.0046 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EDP45337.1 - 0.0089 15.2 0.0 0.016 14.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EDP45337.1 - 0.017 15.0 0.4 0.044 13.7 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EDP45337.1 - 0.021 14.2 0.0 0.075 12.5 0.0 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EDP45337.1 - 0.029 14.6 0.2 0.041 14.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EDP45337.1 - 0.04 13.1 0.4 0.094 11.9 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EDP45337.1 - 0.05 13.1 0.1 0.076 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDP45337.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EDP45337.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDP45337.1 - 0.098 12.5 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EDP45337.1 - 0.11 11.7 0.1 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 EDP45337.1 - 0.12 12.3 0.1 0.45 10.4 0.0 1.9 1 1 0 2 2 2 0 AAA domain Trehalase PF01204.13 EDP45337.1 - 0.13 10.8 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Trehalase MCM PF00493.18 EDP45338.1 - 2e-126 421.2 0.0 3e-126 420.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDP45338.1 - 4.5e-18 65.8 0.0 1e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDP45338.1 - 4.5e-08 32.5 0.1 1e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDP45338.1 - 0.0038 16.8 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP45338.1 - 0.0061 16.0 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EDP45338.1 - 0.099 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Translin PF01997.11 EDP45341.1 - 1.7e-34 119.1 0.1 2.6e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Translin family DUF3846 PF12957.2 EDP45341.1 - 0.008 15.8 0.0 0.77 9.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3846) RPW8 PF05659.6 EDP45341.1 - 0.027 14.0 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3071 PF11268.3 EDP45341.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) RINT1_TIP1 PF04437.8 EDP45342.1 - 1.2e-63 215.4 0.0 6.2e-63 213.0 0.0 2.0 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Solute_trans_a PF03619.11 EDP45343.1 - 5.3e-91 304.7 17.9 6.2e-91 304.5 12.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UCR_14kD PF02271.11 EDP45344.1 - 1.1e-38 131.2 0.5 1.2e-38 131.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Amino_oxidase PF01593.19 EDP45345.1 - 7.2e-08 31.9 0.1 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FBPase PF00316.15 EDP45346.1 - 3.9e-125 416.9 0.0 4.7e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EDP45346.1 - 0.0073 15.6 0.0 0.024 13.9 0.0 1.8 2 1 0 2 2 2 1 Inositol monophosphatase family Perilipin PF03036.11 EDP45347.1 - 6.1e-05 22.0 2.8 0.0017 17.2 0.0 2.1 1 1 0 2 2 2 2 Perilipin family Sec6 PF06046.8 EDP45347.1 - 0.0067 14.5 0.0 0.0088 14.1 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF2383 PF09537.5 EDP45347.1 - 0.012 15.8 0.7 0.022 15.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF3972 PF13118.1 EDP45347.1 - 0.021 14.8 0.4 0.049 13.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DUF2937 PF11157.3 EDP45347.1 - 0.049 12.9 0.6 0.15 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Apolipoprotein PF01442.13 EDP45347.1 - 0.059 12.8 3.2 0.48 9.8 2.2 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.1 EDP45347.1 - 0.14 11.0 1.0 0.22 10.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cyclin_N PF00134.18 EDP45348.1 - 2e-15 56.4 0.2 3.5e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDP45348.1 - 9.3e-11 42.3 1.9 9.6e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 Cyclin Sec7 PF01369.15 EDP45349.1 - 5.6e-31 107.6 0.0 9.3e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Hemerythrin PF01814.18 EDP45349.1 - 0.071 13.2 0.6 0.22 11.6 0.0 2.1 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain WD40 PF00400.27 EDP45350.1 - 2.1e-45 151.0 16.8 7.2e-10 38.3 0.0 11.8 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 EDP45350.1 - 5.9e-17 61.5 0.3 1e-16 60.7 0.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1513 PF07433.6 EDP45350.1 - 0.034 13.0 0.1 0.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EDP45350.1 - 0.078 11.2 0.0 7.1 4.8 0.0 3.4 4 0 0 4 4 4 0 Cytochrome D1 heme domain DEAD PF00270.24 EDP45351.1 - 1.2e-44 151.7 0.3 1.9e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDP45351.1 - 8.8e-21 73.5 0.0 2.3e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDP45351.1 - 8.9e-21 73.2 0.4 1.8e-20 72.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDP45351.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDP45351.1 - 0.13 12.3 0.4 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain Utp21 PF04192.7 EDP45352.1 - 6.5e-47 159.6 0.1 1e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EDP45352.1 - 3.5e-16 58.3 13.0 0.00077 19.2 0.0 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat AAA_5 PF07728.9 EDP45353.1 - 3.1e-113 373.6 0.0 8.7e-21 74.1 0.0 10.0 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDP45353.1 - 9.1e-25 86.7 0.0 6.4e-08 32.2 0.0 7.6 7 1 1 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDP45353.1 - 1.2e-22 80.5 0.1 0.00087 19.4 0.0 7.3 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP45353.1 - 4.9e-21 75.2 0.1 0.022 14.9 0.0 7.7 6 1 0 6 6 6 4 AAA domain AAA_17 PF13207.1 EDP45353.1 - 1.2e-16 61.6 0.6 0.78 10.5 0.0 7.8 7 0 0 7 7 6 4 AAA domain Sigma54_activat PF00158.21 EDP45353.1 - 7.8e-15 54.7 0.1 0.049 13.0 0.0 6.8 6 0 0 6 6 6 4 Sigma-54 interaction domain ABC_tran PF00005.22 EDP45353.1 - 4.3e-14 52.9 0.0 0.33 11.2 0.0 7.0 6 0 0 6 6 6 3 ABC transporter T2SE PF00437.15 EDP45353.1 - 7.9e-14 51.1 0.3 0.056 12.3 0.0 6.5 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_19 PF13245.1 EDP45353.1 - 1.2e-13 50.5 12.2 0.063 13.0 0.1 7.4 6 0 0 6 6 6 3 Part of AAA domain AAA_14 PF13173.1 EDP45353.1 - 3.7e-13 49.4 0.0 0.0012 18.6 0.0 7.1 7 1 0 7 7 6 2 AAA domain AAA_33 PF13671.1 EDP45353.1 - 5.3e-13 49.0 11.1 0.053 13.4 0.0 8.5 8 0 0 8 8 7 2 AAA domain UPF0079 PF02367.12 EDP45353.1 - 8.7e-13 47.9 1.2 0.23 11.0 0.0 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EDP45353.1 - 5.8e-12 45.1 1.5 0.015 14.3 0.0 6.3 6 0 0 6 6 6 3 Zeta toxin AAA_29 PF13555.1 EDP45353.1 - 8e-12 44.5 1.7 0.56 9.7 0.0 5.9 6 0 0 6 6 5 4 P-loop containing region of AAA domain AAA_18 PF13238.1 EDP45353.1 - 1.8e-11 44.4 5.9 0.77 10.0 0.0 7.5 7 0 0 7 7 6 1 AAA domain Sigma54_activ_2 PF14532.1 EDP45353.1 - 5.4e-11 42.6 4.6 0.015 15.3 0.0 7.3 7 0 0 7 7 6 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDP45353.1 - 1.4e-10 40.6 4.0 0.87 8.7 0.0 7.9 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDP45353.1 - 2.5e-10 40.6 55.3 0.0052 16.8 0.1 12.3 11 2 1 12 12 8 5 AAA ATPase domain AAA_28 PF13521.1 EDP45353.1 - 2.2e-09 37.4 1.4 2.6 7.9 0.0 7.7 7 0 0 7 7 7 1 AAA domain RNA_helicase PF00910.17 EDP45353.1 - 2.8e-09 37.1 0.2 2.8 8.1 0.0 6.6 6 0 0 6 6 6 0 RNA helicase DUF258 PF03193.11 EDP45353.1 - 1.9e-08 33.6 0.4 0.23 10.6 0.0 5.6 5 0 0 5 5 5 1 Protein of unknown function, DUF258 NACHT PF05729.7 EDP45353.1 - 2e-07 30.8 3.2 0.44 10.1 0.1 6.2 6 0 0 6 6 5 1 NACHT domain Miro PF08477.8 EDP45353.1 - 5.9e-07 30.0 0.2 7.5 7.0 0.0 6.5 7 0 0 7 7 6 0 Miro-like protein DUF815 PF05673.8 EDP45353.1 - 7.8e-06 24.9 1.2 1.6 7.5 0.0 4.8 5 0 0 5 5 5 2 Protein of unknown function (DUF815) MobB PF03205.9 EDP45353.1 - 2.3e-05 24.0 0.5 5.7 6.6 0.0 5.0 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B vWA-TerF-like PF10138.4 EDP45353.1 - 3.2e-05 23.8 0.1 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus RuvB_N PF05496.7 EDP45353.1 - 0.00011 21.2 6.2 3.5 6.5 0.0 5.8 6 1 0 6 6 6 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 EDP45353.1 - 0.0002 20.8 2.9 1.8 7.9 0.0 5.3 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EDP45353.1 - 0.00033 20.1 0.5 4.4 6.7 0.1 4.4 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.2 EDP45353.1 - 0.0016 18.0 0.0 13 5.2 0.0 5.6 7 0 0 7 7 6 0 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 EDP45353.1 - 0.0019 16.3 0.0 0.5 8.3 0.0 3.7 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor TIP49 PF06068.8 EDP45353.1 - 0.0019 16.9 3.9 0.014 14.1 0.1 3.6 4 0 0 4 4 4 1 TIP49 C-terminus SRP54 PF00448.17 EDP45353.1 - 0.0033 16.9 3.8 3.6 6.9 0.1 4.6 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EDP45353.1 - 0.0077 15.9 0.0 5.9 6.5 0.0 4.2 5 0 0 5 5 4 0 Archaeal ATPase Viral_helicase1 PF01443.13 EDP45353.1 - 0.01 15.3 0.0 3.3 7.1 0.0 4.2 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EDP45353.1 - 0.01 15.0 0.2 11 5.0 0.0 3.4 3 0 0 3 3 3 0 Isopentenyl transferase DUF927 PF06048.6 EDP45353.1 - 0.044 13.0 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF927) SRPRB PF09439.5 EDP45353.1 - 0.069 12.3 0.3 21 4.2 0.0 4.3 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDP45353.1 - 0.11 12.4 0.5 1.5e+02 2.3 0.0 4.8 5 0 0 5 5 4 0 50S ribosome-binding GTPase Bac_DnaA PF00308.13 EDP45353.1 - 0.12 12.0 0.0 64 3.0 0.0 3.9 5 0 0 5 5 4 0 Bacterial dnaA protein ResIII PF04851.10 EDP45353.1 - 0.12 12.1 9.2 2.9 7.6 0.0 4.5 6 0 0 6 6 3 0 Type III restriction enzyme, res subunit Gtr1_RagA PF04670.7 EDP45353.1 - 0.14 11.2 0.4 12 4.9 0.0 3.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region KaiC PF06745.8 EDP45353.1 - 0.14 11.2 3.1 7.3 5.6 0.0 3.7 4 0 0 4 4 3 0 KaiC AAA_7 PF12775.2 EDP45353.1 - 0.18 10.8 0.0 17 4.4 0.0 3.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 Peptidase_S41 PF03572.13 EDP45353.1 - 0.25 10.7 0.1 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S41 PEPCK_ATP PF01293.15 EDP45353.1 - 0.28 9.6 0.0 0.57 8.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_23 PF13476.1 EDP45353.1 - 0.34 11.1 0.0 0.34 11.1 0.0 6.4 6 1 0 6 6 5 0 AAA domain AAA_21 PF13304.1 EDP45353.1 - 0.35 10.8 0.0 16 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 EDP45353.1 - 0.47 9.6 5.1 36 3.4 0.0 4.5 5 0 0 5 5 4 0 PhoH-like protein NMN_transporter PF04973.7 EDP45353.1 - 0.5 9.7 2.2 0.5 9.7 0.1 1.9 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Rad17 PF03215.10 EDP45353.1 - 1.1 7.8 0.9 79 1.7 0.0 3.5 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 EDP45353.1 - 1.5 8.2 5.5 2.6 7.5 0.1 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Phage_holin_4 PF05105.7 EDP45353.1 - 3 7.5 0.0 5.7 6.6 0.0 1.4 1 0 0 1 1 1 0 Holin family DUF809 PF05663.6 EDP45353.1 - 6.4 6.7 0.0 20 5.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Foie-gras_1 PF11817.3 EDP45354.1 - 2e-20 73.3 12.1 3e-14 53.0 1.2 2.6 2 1 1 3 3 3 2 Foie gras liver health family 1 Gryzun PF07919.7 EDP45354.1 - 2.2e-07 29.5 0.1 1.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TRAPPC10 PF12584.3 EDP45354.1 - 0.0014 18.1 0.3 0.0055 16.2 0.0 2.1 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 HA2 PF04408.18 EDP45355.1 - 1e-16 60.7 0.2 4.5e-16 58.7 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDP45355.1 - 6.6e-14 51.5 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDP45355.1 - 4.1e-11 42.6 0.1 8.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EDP45355.1 - 7.7e-10 38.6 0.0 2.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold KaiC PF06745.8 EDP45355.1 - 0.00046 19.3 0.0 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EDP45355.1 - 0.00088 19.4 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDP45355.1 - 0.0035 16.2 0.3 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 EDP45355.1 - 0.0046 16.8 0.0 0.061 13.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EDP45355.1 - 0.018 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EDP45355.1 - 0.019 14.1 0.1 0.25 10.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EDP45355.1 - 0.033 13.9 0.6 0.5 10.1 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain AAA_25 PF13481.1 EDP45355.1 - 0.048 13.0 0.5 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDP45355.1 - 0.14 11.4 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Sec2p PF06428.6 EDP45356.1 - 8.9e-18 64.0 4.8 8.9e-18 64.0 3.3 2.8 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p RPAP1_N PF08621.5 EDP45356.1 - 0.015 14.8 0.2 0.015 14.8 0.2 2.3 2 0 0 2 2 2 0 RPAP1-like, N-terminal Fib_alpha PF08702.5 EDP45356.1 - 3.7 7.6 14.9 1.3 9.1 1.4 3.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1227 PF06777.6 EDP45357.1 - 1.5e-59 199.9 0.3 3.2e-59 198.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EDP45357.1 - 1.9e-48 164.1 0.1 2.7e-47 160.4 0.0 2.5 2 1 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 EDP45357.1 - 3.5e-45 153.9 0.0 7.7e-45 152.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EDP45357.1 - 0.003 17.4 0.0 0.098 12.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDP45357.1 - 0.0074 15.7 0.3 1.6 8.2 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EDP45357.1 - 0.012 14.4 0.0 0.67 8.6 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EDP45357.1 - 0.051 13.7 0.2 4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_34 PF13872.1 EDP45357.1 - 0.13 11.0 0.0 7.2 5.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 YtxC PF08812.6 EDP45357.1 - 0.34 10.3 2.8 0.36 10.2 0.0 2.3 3 0 0 3 3 3 0 YtxC-like family ABC_tran PF00005.22 EDP45358.1 - 3.7e-43 147.1 0.0 1.5e-21 77.1 0.0 4.6 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EDP45358.1 - 1.4e-16 61.3 0.4 0.00065 19.7 0.0 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EDP45358.1 - 2.2e-13 49.9 2.0 0.0032 16.7 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDP45358.1 - 1.4e-09 37.3 0.2 0.00085 18.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDP45358.1 - 8.3e-07 29.5 1.1 0.052 13.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDP45358.1 - 2.1e-06 27.9 0.0 0.14 12.3 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_10 PF12846.2 EDP45358.1 - 3.4e-06 26.7 0.6 0.077 12.4 0.0 4.3 4 1 1 5 5 5 2 AAA-like domain HEAT_2 PF13646.1 EDP45358.1 - 3.4e-06 27.2 0.0 0.037 14.2 0.1 3.8 2 1 1 3 3 3 2 HEAT repeats CLASP_N PF12348.3 EDP45358.1 - 4.6e-06 26.1 0.0 0.033 13.5 0.0 2.6 1 1 1 2 2 2 2 CLASP N terminal AAA_17 PF13207.1 EDP45358.1 - 9.2e-06 26.4 0.0 0.17 12.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EDP45358.1 - 1.1e-05 25.8 0.0 0.039 14.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 EDP45358.1 - 3.1e-05 23.7 1.0 0.011 15.6 0.0 3.5 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EDP45358.1 - 5e-05 22.8 0.0 2.5 7.5 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family NACHT PF05729.7 EDP45358.1 - 0.00014 21.5 0.0 0.58 9.7 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_15 PF13175.1 EDP45358.1 - 0.00014 21.0 0.3 0.36 9.8 0.1 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 EDP45358.1 - 0.00037 20.3 0.0 0.7 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EDP45358.1 - 0.00062 19.4 0.1 0.61 9.7 0.1 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDP45358.1 - 0.00068 18.8 0.0 0.62 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDP45358.1 - 0.001 18.9 0.0 0.94 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDP45358.1 - 0.002 18.4 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EDP45358.1 - 0.002 18.3 0.0 2.4 8.3 0.0 4.4 6 0 0 6 6 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDP45358.1 - 0.0027 17.7 0.0 3.6 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDP45358.1 - 0.0027 17.1 0.0 4.3 6.6 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EDP45358.1 - 0.0036 15.8 0.3 1.1 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EDP45358.1 - 0.0038 17.0 5.6 0.21 11.3 0.1 4.0 4 0 0 4 4 4 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 EDP45358.1 - 0.0048 17.0 0.0 6.7 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase HEAT_EZ PF13513.1 EDP45358.1 - 0.0049 17.3 0.6 13 6.4 0.0 5.3 4 1 2 6 6 6 0 HEAT-like repeat AAA_30 PF13604.1 EDP45358.1 - 0.0053 16.3 0.0 6.2 6.3 0.0 3.4 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 EDP45358.1 - 0.0059 15.4 0.4 0.51 9.0 0.0 2.6 2 0 0 2 2 2 1 ArgK protein Chromo PF00385.19 EDP45358.1 - 0.006 16.2 0.5 0.018 14.7 0.0 2.1 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain NB-ARC PF00931.17 EDP45358.1 - 0.0061 15.4 0.5 2.3 6.9 0.1 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 EDP45358.1 - 0.0069 16.3 7.6 0.17 11.8 0.7 4.3 3 1 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EDP45358.1 - 0.0078 15.9 1.5 4.6 6.8 0.0 3.8 4 0 0 4 4 3 0 Archaeal ATPase AAA_14 PF13173.1 EDP45358.1 - 0.037 13.9 0.0 12 5.8 0.0 3.9 4 1 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 EDP45358.1 - 0.069 12.6 1.1 4.4 6.7 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EDP45358.1 - 0.075 11.7 4.6 1.4 7.4 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit AAA_19 PF13245.1 EDP45358.1 - 0.13 11.9 0.4 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UME PF08064.8 EDP45358.1 - 0.14 12.1 0.3 0.36 10.8 0.2 1.8 1 0 0 1 1 1 0 UME (NUC010) domain AAA_5 PF07728.9 EDP45358.1 - 0.18 11.5 4.7 25 4.5 0.0 4.7 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) She9_MDM33 PF05546.6 EDP45359.1 - 2.9e-57 193.5 7.5 3.7e-57 193.2 5.2 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family AMP-binding PF00501.23 EDP45360.1 - 5e-90 301.8 0.0 6.2e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDP45360.1 - 1e-18 68.0 1.3 1.6e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP-synt_E PF05680.7 EDP45361.1 - 7e-21 73.9 0.1 7.1e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain AIF-MLS PF14962.1 EDP45361.1 - 0.034 13.7 0.2 0.038 13.6 0.1 1.0 1 0 0 1 1 1 0 Mitochondria Localisation Sequence NAC PF01849.13 EDP45362.1 - 1.8e-19 69.0 0.1 3.1e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 NAC domain OmpH PF03938.9 EDP45363.1 - 0.63 9.9 4.9 0.76 9.6 3.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) U79_P34 PF03064.11 EDP45363.1 - 1.1 8.7 17.9 1.3 8.4 12.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 D123 PF07065.9 EDP45364.1 - 2.3e-74 250.1 0.0 2.7e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EDP45364.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4343) tRNA-synt_2 PF00152.15 EDP45365.1 - 8.8e-56 189.0 0.0 2.6e-55 187.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDP45365.1 - 2.6e-07 30.4 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ECH_C PF13766.1 EDP45366.1 - 9.4e-20 70.9 0.0 2.8e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EDP45366.1 - 1.9e-14 53.3 0.2 2.8e-07 29.9 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase family DMRL_synthase PF00885.14 EDP45367.1 - 3.5e-50 169.4 0.0 4.2e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Mit_ribos_Mrp51 PF11709.3 EDP45368.1 - 8.7e-17 61.3 0.5 2.4e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit Coatomer_WDAD PF04053.9 EDP45369.1 - 2.5e-126 422.0 0.0 4.1e-126 421.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EDP45369.1 - 6.5e-63 212.7 0.0 9.9e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EDP45369.1 - 6.3e-59 193.8 8.0 4.5e-11 42.1 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 EDP45369.1 - 0.00083 17.6 7.7 0.047 11.8 0.1 4.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDP45369.1 - 0.14 10.8 2.9 7.8 5.1 0.0 3.5 1 1 1 3 3 3 0 Nup133 N terminal like Rot1 PF10681.4 EDP45370.1 - 1.2e-49 168.5 5.9 1.5e-49 168.2 4.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2716 PF10898.3 EDP45370.1 - 0.018 15.0 0.1 0.03 14.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2716) Gpi16 PF04113.9 EDP45371.1 - 9.2e-77 258.3 0.0 4e-45 153.8 0.0 2.7 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component FAD_binding_8 PF08022.7 EDP45372.1 - 2.3e-14 53.1 0.0 5.7e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDP45372.1 - 1.3e-13 51.1 0.0 6.4e-13 48.8 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NUC173 PF08161.7 EDP45373.1 - 1.7e-39 135.2 0.0 4.1e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 NUC173 domain CAS_CSE1 PF03378.10 EDP45373.1 - 0.096 10.9 0.0 0.28 9.4 0.0 1.7 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus DNA_pol3_a_NII PF11490.3 EDP45374.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II LETM1 PF07766.8 EDP45375.1 - 9.1e-87 290.4 1.1 9.1e-87 290.4 0.8 2.0 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 EDP45375.1 - 0.0001 22.3 0.9 0.0039 17.3 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 EDP45375.1 - 0.00048 19.6 0.3 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDP45375.1 - 0.0048 16.1 0.5 4.1 6.9 0.0 4.0 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.1 EDP45375.1 - 0.03 14.1 0.2 21 5.3 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Syntaxin-6_N PF09177.6 EDP45375.1 - 0.046 14.1 4.8 0.15 12.5 0.0 3.4 1 1 3 4 4 4 0 Syntaxin 6, N-terminal WD40 PF00400.27 EDP45376.1 - 2.7e-26 90.4 19.6 3.7e-06 26.6 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat NLE PF08154.7 EDP45376.1 - 2.9e-14 52.8 0.0 4.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Peptidase_M13_N PF05649.8 EDP45377.1 - 1.2e-72 245.1 0.0 1.4e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EDP45377.1 - 1.4e-50 171.3 0.0 1.9e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 EDP45378.1 - 1.1e-53 182.6 0.0 2.3e-53 181.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 EDP45378.1 - 1.2e-28 99.7 0.1 2.8e-16 59.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M13 MAGE_N PF12440.3 EDP45378.1 - 0.0012 19.0 3.2 0.0037 17.5 2.2 1.8 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal DUF1943 PF09172.6 EDP45378.1 - 0.018 13.9 0.3 0.032 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Peptidase_S49_N PF08496.5 EDP45378.1 - 0.54 10.0 3.9 0.94 9.2 2.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF155 PF02582.9 EDP45379.1 - 2.8e-44 151.0 0.0 5e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2040 PF09745.4 EDP45380.1 - 2.7e-36 124.2 22.0 2.7e-36 124.2 15.3 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Acetate_kinase PF00871.12 EDP45380.1 - 0.13 10.7 0.1 1.2 7.6 0.2 1.9 2 0 0 2 2 2 0 Acetokinase family ACPS PF01648.15 EDP45381.1 - 1.5e-14 53.7 0.0 2e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily Vps55 PF04133.9 EDP45382.1 - 4.8e-17 61.8 1.4 5.1e-17 61.7 1.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 RRM_1 PF00076.17 EDP45383.1 - 0.0019 17.7 0.0 0.0066 16.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP45383.1 - 0.0021 17.8 0.0 0.019 14.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gemini_AL2 PF01440.11 EDP45383.1 - 6.5 6.8 9.0 3.4 7.7 3.2 2.7 2 0 0 2 2 2 0 Geminivirus AL2 protein TRAPPC9-Trs120 PF08626.6 EDP45384.1 - 4.3e-70 236.3 0.0 1.2e-46 158.7 0.0 3.8 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit PALP PF00291.20 EDP45385.1 - 1.9e-49 168.5 0.0 3e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HLH PF00010.21 EDP45386.1 - 7.1e-05 22.4 0.1 0.0002 20.9 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SKN1 PF03935.10 EDP45387.1 - 8.1e-179 594.9 4.9 9.7e-179 594.7 3.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Adaptin_N PF01602.15 EDP45388.1 - 6.8e-104 348.0 7.2 8.1e-104 347.8 5.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDP45388.1 - 8.4e-13 48.5 3.6 1.1e-11 44.9 0.2 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDP45388.1 - 3.3e-10 40.1 3.7 0.00018 21.7 0.2 3.7 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EDP45388.1 - 0.00028 20.7 1.1 0.13 12.4 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EDP45388.1 - 0.0019 18.6 1.3 3.4 8.2 0.1 4.2 3 1 0 3 3 3 1 HEAT-like repeat UTP15_C PF09384.5 EDP45389.1 - 7e-44 149.1 0.0 1.1e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EDP45389.1 - 1.7e-30 103.7 4.7 1.4e-07 31.1 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EDP45389.1 - 0.00064 17.9 1.0 0.8 7.7 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EDP45389.1 - 0.007 14.7 0.0 0.016 13.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 EDP45389.1 - 0.012 15.2 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S21e PF01249.13 EDP45390.1 - 5.8e-33 112.6 0.1 6.3e-33 112.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PUF PF00806.14 EDP45391.1 - 5.9e-05 22.3 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat PUF PF00806.14 EDP45392.1 - 1.7e-43 143.6 1.6 1.4e-06 27.4 0.0 6.3 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RabGAP-TBC PF00566.13 EDP45393.1 - 1.4e-26 93.3 1.9 6.5e-26 91.1 1.3 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CoA_trans PF01144.18 EDP45394.1 - 2.9e-93 311.0 2.4 2.6e-56 190.2 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EDP45394.1 - 0.0086 15.7 0.1 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF21 PF01595.15 EDP45395.1 - 2.2e-28 98.7 0.2 3.4e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EDP45395.1 - 0.0014 18.3 0.6 5.4 6.8 0.0 3.7 3 0 0 3 3 3 2 CBS domain SirB PF04247.7 EDP45395.1 - 0.037 13.7 0.6 0.062 13.0 0.4 1.2 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB CTDII PF01556.13 EDP45396.1 - 4.5e-23 80.9 0.1 2e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDP45396.1 - 2.5e-15 56.2 19.9 4.1e-15 55.5 13.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 EDP45396.1 - 0.018 15.3 8.1 0.28 11.5 1.4 2.4 2 0 0 2 2 2 0 Cytochrome c3 HypA PF01155.14 EDP45396.1 - 0.019 14.6 12.0 0.5 10.0 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_CIII PF02085.11 EDP45396.1 - 0.78 9.8 8.3 1.9 8.6 5.7 1.7 1 1 0 1 1 1 0 Class III cytochrome C family zinc-ribbons_6 PF07191.7 EDP45396.1 - 2.6 7.8 9.9 7.8 6.3 2.5 2.4 2 0 0 2 2 2 0 zinc-ribbons His_Phos_1 PF00300.17 EDP45397.1 - 3.2e-17 63.0 0.2 8.3e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) IncA PF04156.9 EDP45397.1 - 0.068 12.7 0.1 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 IncA protein KxDL PF10241.4 EDP45397.1 - 0.11 12.4 0.3 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF325 PF03804.8 EDP45397.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral domain of unknown function COG2 PF06148.6 EDP45397.1 - 0.7 9.7 3.1 0.41 10.5 0.8 1.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L14 PF00238.14 EDP45398.1 - 1.5e-40 137.7 1.0 1.7e-40 137.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TRM PF02005.11 EDP45399.1 - 1.9e-89 300.2 0.0 2.4e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase TRM PF02005.11 EDP45400.1 - 1.4e-08 34.1 0.0 1.7e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Ofd1_CTDD PF10637.4 EDP45401.1 - 2.1e-80 269.6 0.0 6.2e-74 248.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EDP45401.1 - 2e-16 60.3 1.8 2.5e-16 59.9 0.4 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EBV-NA3 PF05009.7 EDP45401.1 - 0.0099 15.1 2.8 0.018 14.3 1.9 1.4 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FYDLN_acid PF09538.5 EDP45401.1 - 0.89 10.1 15.2 2.3 8.8 10.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) YL1 PF05764.8 EDP45401.1 - 3.7 7.0 16.2 9 5.8 11.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.11 EDP45401.1 - 6.6 5.6 7.7 11 4.8 5.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.3 EDP45401.1 - 6.8 6.5 17.1 12 5.7 11.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA PF00004.24 EDP45402.1 - 3.1e-52 176.2 0.0 2.1e-42 144.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EDP45402.1 - 9e-22 76.9 0.5 2.1e-21 75.7 0.4 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 EDP45402.1 - 7.5e-11 42.9 0.0 7.3e-05 23.5 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDP45402.1 - 6.8e-10 39.2 7.9 0.00056 19.9 2.3 4.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EDP45402.1 - 1.8e-07 31.0 0.3 0.041 13.7 0.3 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDP45402.1 - 8.3e-07 29.2 0.1 0.072 13.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EDP45402.1 - 2.8e-05 23.7 0.0 0.053 13.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EDP45402.1 - 2.8e-05 24.4 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDP45402.1 - 3.6e-05 23.6 0.0 0.035 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP45402.1 - 6.1e-05 22.7 6.7 0.087 12.4 2.1 4.1 3 1 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 EDP45402.1 - 0.00014 21.5 0.1 0.46 10.2 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 EDP45402.1 - 0.00034 20.3 0.0 0.57 9.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDP45402.1 - 0.00039 19.5 0.0 0.0028 16.7 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EDP45402.1 - 0.00055 20.0 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_29 PF13555.1 EDP45402.1 - 0.00076 18.9 0.1 0.0048 16.3 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EDP45402.1 - 0.00084 19.3 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EDP45402.1 - 0.0012 18.0 0.2 0.79 8.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 EDP45402.1 - 0.0024 16.7 0.1 1.5 7.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 EDP45402.1 - 0.0034 16.4 0.1 0.97 8.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin SKI PF01202.17 EDP45402.1 - 0.0038 17.1 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_25 PF13481.1 EDP45402.1 - 0.0038 16.6 6.1 5.2 6.4 0.3 4.3 2 2 1 4 4 4 0 AAA domain TIP49 PF06068.8 EDP45402.1 - 0.0067 15.1 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_2 PF07724.9 EDP45402.1 - 0.0089 15.9 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDP45402.1 - 0.015 14.1 0.0 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EDP45402.1 - 0.016 14.7 2.2 0.26 10.8 0.1 3.4 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.10 EDP45402.1 - 0.018 13.7 0.0 0.23 10.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EDP45402.1 - 0.018 15.3 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 EDP45402.1 - 0.021 14.5 0.1 41 3.7 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase IstB_IS21 PF01695.12 EDP45402.1 - 0.022 14.1 0.2 0.91 8.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 EDP45402.1 - 0.039 13.5 0.2 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EDP45402.1 - 0.09 12.3 0.1 13 5.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDP45402.1 - 0.11 12.2 1.1 3.5 7.3 0.0 2.8 3 0 0 3 3 2 0 NTPase Cytidylate_kin2 PF13189.1 EDP45402.1 - 0.11 12.3 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 1 0 Cytidylate kinase-like family ATP_bind_1 PF03029.12 EDP45402.1 - 0.12 11.9 0.3 0.3 10.5 0.0 1.8 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 EDP45402.1 - 0.18 10.7 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EDP45402.1 - 0.29 10.5 1.5 14 5.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gly_transf_sug PF04488.10 EDP45403.1 - 3.2e-19 69.2 0.0 6.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EDP45403.1 - 0.065 11.7 0.5 0.57 8.5 0.1 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain ABC_membrane PF00664.18 EDP45404.1 - 1.8e-60 204.6 34.2 7.9e-34 117.3 8.9 2.9 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDP45404.1 - 7.8e-47 159.0 0.0 4.3e-29 101.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDP45404.1 - 7.2e-06 25.3 0.1 0.038 13.1 0.0 3.7 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EDP45404.1 - 0.00028 20.7 0.2 0.32 10.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EDP45404.1 - 0.00054 19.4 1.2 0.21 11.1 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.12 EDP45404.1 - 0.0018 18.1 4.2 0.066 13.0 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EDP45404.1 - 0.0018 18.2 5.2 0.026 14.5 0.2 3.2 4 0 0 4 4 2 1 AAA ATPase domain AAA_21 PF13304.1 EDP45404.1 - 0.0056 16.6 1.4 1 9.2 0.0 3.0 4 0 0 4 4 4 1 AAA domain ArgK PF03308.11 EDP45404.1 - 0.0091 14.7 1.1 0.022 13.5 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 EDP45404.1 - 0.0093 15.7 2.2 0.23 11.2 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EDP45404.1 - 0.015 14.7 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EDP45404.1 - 0.017 14.5 0.1 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EDP45404.1 - 0.018 14.2 0.3 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EDP45404.1 - 0.028 14.8 0.7 14 6.2 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_17 PF13207.1 EDP45404.1 - 0.051 14.3 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EDP45404.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EDP45404.1 - 0.084 12.5 0.2 0.53 9.9 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EDP45404.1 - 0.13 11.8 1.6 2 7.9 0.3 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDP45404.1 - 0.18 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EDP45404.1 - 0.24 10.8 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain E1-E2_ATPase PF00122.15 EDP45404.1 - 0.42 9.6 4.9 2.6 6.9 0.3 2.6 2 0 0 2 2 2 0 E1-E2 ATPase Aconitase PF00330.15 EDP45405.1 - 8.1e-50 169.6 0.0 9.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase PF00330.15 EDP45406.1 - 5.9e-68 229.4 0.1 1.7e-67 227.9 0.1 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDP45406.1 - 9.5e-32 109.8 0.0 2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 EDP45406.1 - 0.0031 17.3 1.3 0.049 13.4 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 DUF521 PF04412.8 EDP45406.1 - 0.034 12.6 0.0 0.057 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Phosphoprotein PF00922.12 EDP45406.1 - 0.28 10.3 0.7 0.44 9.7 0.5 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein SGS PF05002.10 EDP45407.1 - 4.6e-28 96.7 0.1 8.2e-28 95.9 0.1 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EDP45407.1 - 3.4e-10 40.3 0.0 5.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 CS domain Alg6_Alg8 PF03155.10 EDP45408.1 - 7.9e-117 390.9 34.7 9.9e-117 390.6 24.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family OMPdecase PF00215.19 EDP45410.1 - 1.6e-69 233.7 0.0 3.2e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HhH-GPD PF00730.20 EDP45410.1 - 6.5e-18 65.0 0.0 2e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDP45410.1 - 2.2e-07 30.1 0.0 8.4e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EDP45410.1 - 0.028 14.5 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Kinesin PF00225.18 EDP45411.1 - 2.3e-23 82.4 0.1 2.6e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain PhoH PF02562.11 EDP45411.1 - 0.02 14.0 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EDP45411.1 - 0.035 13.0 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 EDP45411.1 - 0.077 11.9 0.2 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase DEAD PF00270.24 EDP45411.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Kinesin PF00225.18 EDP45412.1 - 1.1e-40 139.4 0.1 1.1e-40 139.4 0.1 2.0 3 0 0 3 3 3 1 Kinesin motor domain DUF2730 PF10805.3 EDP45412.1 - 4 7.2 12.2 1.9 8.2 4.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) CM_2 PF01817.16 EDP45413.1 - 0.0015 18.6 0.0 0.021 14.9 0.0 2.4 2 1 0 2 2 2 1 Chorismate mutase type II zf-rbx1 PF12678.2 EDP45414.1 - 1.5e-08 34.6 1.0 3.5e-08 33.4 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDP45414.1 - 2.4e-08 33.6 7.3 5.5e-08 32.5 5.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDP45414.1 - 7.9e-05 22.2 8.4 0.00015 21.3 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDP45414.1 - 0.00015 21.5 2.4 0.00034 20.4 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EDP45414.1 - 0.0014 18.5 3.9 0.0034 17.3 2.7 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EDP45414.1 - 0.018 15.1 6.4 0.038 14.0 4.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EDP45414.1 - 0.051 13.5 8.8 0.13 12.3 6.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cellulase-like PF12876.2 EDP45414.1 - 0.052 13.9 0.0 0.31 11.5 0.0 2.4 1 0 0 1 1 1 0 Sugar-binding cellulase-like zf-RING_4 PF14570.1 EDP45414.1 - 0.11 12.0 4.9 0.21 11.2 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EDP45414.1 - 0.17 11.5 4.8 0.34 10.6 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP45414.1 - 0.31 10.7 7.3 0.62 9.8 5.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 EDP45414.1 - 0.58 9.9 4.8 1.3 8.8 3.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EDP45414.1 - 5.3 6.8 6.0 10 5.9 4.2 1.4 1 0 0 1 1 1 0 PHD-finger Exo_endo_phos PF03372.18 EDP45415.1 - 2.9e-12 47.0 0.1 8.9e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family LEA_2 PF03168.8 EDP45416.1 - 0.045 14.1 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF912 PF06024.7 EDP45416.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CN_hydrolase PF00795.17 EDP45418.1 - 1.3e-21 76.7 0.0 1.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPP_enzyme_N PF02776.13 EDP45419.1 - 6.6e-39 133.1 0.0 1.9e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDP45419.1 - 4.5e-22 78.2 0.0 8.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDP45419.1 - 3.1e-15 56.0 0.1 9.3e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Rad50_zn_hook PF04423.9 EDP45420.1 - 0.016 14.6 3.1 0.021 14.3 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Nop14 PF04147.7 EDP45420.1 - 0.11 10.3 4.2 0.19 9.5 2.9 1.3 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EDP45420.1 - 0.35 10.8 16.7 1.3 9.0 1.4 4.0 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDP45420.1 - 2.5 7.8 16.0 0.73 9.5 0.4 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-C4pol PF14260.1 EDP45420.1 - 4.7 7.2 7.7 7.5 6.6 0.2 3.0 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta AAA_16 PF13191.1 EDP45421.1 - 5.6e-10 39.5 3.9 5.3e-07 29.8 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EDP45421.1 - 1.8e-08 34.5 0.2 1.5e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EDP45421.1 - 5.9e-06 26.5 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDP45421.1 - 0.0011 18.6 1.3 0.0028 17.3 0.1 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 EDP45421.1 - 0.0058 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDP45421.1 - 0.0083 15.7 0.2 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EDP45421.1 - 0.012 15.1 0.0 0.084 12.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA12 PF10443.4 EDP45421.1 - 0.014 13.9 0.1 0.034 12.6 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein NB-ARC PF00931.17 EDP45421.1 - 0.015 14.2 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF1771 PF08590.5 EDP45421.1 - 0.036 14.0 0.5 0.13 12.3 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) cobW PF02492.14 EDP45421.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EDP45421.1 - 0.066 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SR-25 PF10500.4 EDP45421.1 - 0.14 11.6 17.8 0.52 9.7 2.7 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4604 PF15377.1 EDP45421.1 - 0.19 11.9 6.2 0.43 10.7 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) WD40 PF00400.27 EDP45422.1 - 4.9e-47 156.2 11.8 6.6e-11 41.6 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDP45422.1 - 7.3e-10 37.5 6.7 0.0043 15.2 0.0 4.9 3 2 2 5 5 5 5 Nucleoporin Nup120/160 APG6 PF04111.7 EDP45422.1 - 3.4 6.6 5.6 4.9 6.1 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAML PF14963.1 EDP45423.1 - 1.1 8.5 6.6 0.12 11.7 1.1 1.9 2 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DNA_topoisoIV PF00521.15 EDP45424.1 - 1.1e-121 406.6 0.0 1.9e-121 405.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EDP45424.1 - 2.2e-32 111.6 0.0 6.1e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDP45424.1 - 2.7e-14 52.9 0.0 6.9e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EDP45424.1 - 3.7e-08 33.0 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDP45424.1 - 0.0027 17.3 0.4 0.0065 16.1 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH PF00378.15 EDP45425.1 - 3.8e-71 239.0 2.2 5e-71 238.6 1.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EDP45425.1 - 0.0036 17.0 1.0 0.13 12.0 0.0 2.6 2 1 0 2 2 2 1 Peptidase family S49 RRM_5 PF13893.1 EDP45426.1 - 0.0003 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP45426.1 - 0.0041 17.0 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDP45426.1 - 0.014 14.9 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAXIP1_C PF15364.1 EDP45426.1 - 0.17 11.7 4.2 2.1 8.2 2.2 2.5 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Phosphodiest PF01663.17 EDP45427.1 - 4.9e-10 39.2 0.4 8.4e-10 38.5 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDP45427.1 - 0.00011 21.6 0.6 0.00018 20.9 0.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EDP45427.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Sulfatase PCI PF01399.22 EDP45428.1 - 2e-06 28.0 0.0 4.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EDP45428.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 EDP45428.1 - 0.047 14.3 1.4 0.047 14.3 1.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDP45428.1 - 0.05 13.5 0.6 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDP45428.1 - 0.063 13.9 0.3 0.063 13.9 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDP45428.1 - 0.068 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 EDP45428.1 - 0.072 12.9 0.7 0.18 11.7 0.5 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DNA_pol_E_B PF04042.11 EDP45429.1 - 1.7e-36 125.4 0.4 2.3e-36 125.0 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dus PF01207.12 EDP45431.1 - 1.3e-46 158.9 0.0 1.2e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EDP45431.1 - 8.7e-07 28.4 7.2 0.0044 16.6 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA-synt_1g PF09334.6 EDP45432.1 - 2.2e-143 477.6 0.0 2.7e-143 477.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 EDP45432.1 - 1.9e-09 37.0 0.8 1.9e-09 37.0 0.5 1.8 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 EDP45432.1 - 1e-08 33.6 0.3 3.1e-05 22.2 0.0 3.3 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 EDP45432.1 - 1.5 8.6 9.8 3.7 7.4 4.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF2797 PF10977.3 EDP45432.1 - 6.3 6.3 6.7 0.72 9.4 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) IPP-2 PF04979.9 EDP45433.1 - 0.00013 22.1 1.8 0.00016 21.8 1.2 1.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF2890 PF11081.3 EDP45434.1 - 0.31 11.0 2.8 0.49 10.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PHD PF00628.24 EDP45435.1 - 2.7e-08 33.3 16.4 4.5e-08 32.6 11.4 1.4 1 0 0 1 1 1 1 PHD-finger MIP-T3 PF10243.4 EDP45435.1 - 3.2 6.1 34.7 0.089 11.2 13.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BP28CT PF08146.7 EDP45436.1 - 7.8e-27 93.8 3.4 8.7e-27 93.7 0.1 2.9 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EDP45436.1 - 6.4e-26 90.6 0.8 6.4e-26 90.6 0.5 6.6 7 0 0 7 7 7 2 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EDP45436.1 - 0.0079 16.2 6.4 0.022 14.8 0.4 4.8 3 0 0 3 3 3 1 HEAT repeat XPG_I PF00867.13 EDP45437.1 - 1.6e-11 44.0 0.1 5.2e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 XPG I-region NUDIX PF00293.23 EDP45438.1 - 1.9e-16 59.9 3.3 2.9e-16 59.3 2.3 1.4 1 1 0 1 1 1 1 NUDIX domain YppG PF14179.1 EDP45439.1 - 0.42 11.2 2.9 0.44 11.1 1.4 1.4 1 1 0 1 1 1 0 YppG-like protein Ribosomal_L7Ae PF01248.21 EDP45440.1 - 6.6e-22 76.8 0.2 1e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ish1 PF10281.4 EDP45441.1 - 1.4e-39 133.8 25.0 1.9e-07 31.0 2.2 6.7 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EDP45441.1 - 1.2e-08 34.2 0.1 0.00064 19.2 0.0 4.4 5 0 0 5 5 5 2 HeH/LEM domain SAP PF02037.22 EDP45441.1 - 0.00019 20.8 0.0 0.41 10.1 0.0 4.0 3 1 0 3 3 3 1 SAP domain LEM PF03020.10 EDP45441.1 - 0.017 14.5 0.0 5.1 6.6 0.0 3.8 5 0 0 5 5 5 0 LEM domain DUF1470 PF07336.6 EDP45441.1 - 0.04 14.2 0.4 22 5.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1470) DUF883 PF05957.8 EDP45441.1 - 0.66 10.4 6.4 8.9 6.7 0.7 3.7 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) SbcCD_C PF13558.1 EDP45442.1 - 3.2e-08 33.3 0.0 1.3e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EDP45442.1 - 0.0092 15.2 5.0 0.019 14.2 3.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDP45443.1 - 5.3e-15 56.2 0.0 5.7e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EDP45443.1 - 4.9e-09 35.7 0.0 5.6e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDP45443.1 - 9.5e-07 28.1 0.0 9.5e-07 28.1 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.1 EDP45443.1 - 2.9e-06 26.0 0.0 3.1e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDP45443.1 - 4.2e-05 22.9 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EDP45443.1 - 4.6e-05 23.5 0.0 5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDP45443.1 - 0.00039 20.7 0.0 0.00046 20.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EDP45443.1 - 0.00097 19.1 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EDP45443.1 - 0.0059 16.3 0.1 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EDP45443.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EDP45443.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.22 EDP45443.1 - 0.03 13.7 0.1 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDP45443.1 - 0.033 13.3 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EDP45443.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDP45443.1 - 0.035 13.5 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EDP45443.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EDP45443.1 - 0.047 13.1 0.1 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EDP45443.1 - 0.055 13.6 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EDP45443.1 - 0.07 11.7 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SRP54 PF00448.17 EDP45443.1 - 0.1 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EDP45443.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 EDP45444.1 - 1e-28 99.8 11.5 1e-28 99.8 8.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase ThiF PF00899.16 EDP45445.1 - 3.3e-13 49.6 0.0 5.2e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family RRN7 PF11781.3 EDP45446.1 - 0.059 12.8 0.6 0.16 11.4 0.4 1.8 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 RE_TaqI PF09573.5 EDP45446.1 - 0.18 10.8 0.7 0.39 9.8 0.1 1.7 2 0 0 2 2 2 0 TaqI restriction endonuclease TPR_MLP1_2 PF07926.7 EDP45448.1 - 1.9e-05 24.4 21.5 1.9e-05 24.4 14.9 14.5 6 5 6 13 13 13 4 TPR/MLP1/MLP2-like protein SCP2 PF02036.12 EDP45449.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 SCP-2 sterol transfer family CHD5 PF04420.9 EDP45450.1 - 4.9e-32 110.8 0.2 6.6e-32 110.3 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein Mononeg_RNA_pol PF00946.14 EDP45450.1 - 0.0069 13.8 0.2 0.0086 13.5 0.1 1.0 1 0 0 1 1 1 1 Mononegavirales RNA dependent RNA polymerase DASH_Hsk3 PF08227.6 EDP45450.1 - 0.1 12.8 0.7 0.17 12.1 0.1 1.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like GATase_4 PF13230.1 EDP45451.1 - 2.7e-05 22.9 0.0 3.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDP45451.1 - 0.0062 16.4 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain Paf67 PF10255.4 EDP45452.1 - 1e-119 400.0 8.9 2.5e-90 303.2 4.8 2.1 1 1 1 2 2 2 2 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EDP45452.1 - 0.0026 17.5 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDP45452.1 - 0.015 14.8 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EDP45452.1 - 0.019 14.7 0.3 0.05 13.3 0.1 1.7 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 EDP45452.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.5 2 2 0 2 2 2 0 TPR repeat DUF202 PF02656.10 EDP45453.1 - 0.0065 16.6 4.7 0.0068 16.5 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2149 PF09919.4 EDP45453.1 - 0.04 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF2910 PF11139.3 EDP45453.1 - 0.051 12.7 1.8 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Ninjurin PF04923.7 EDP45453.1 - 0.38 10.4 2.5 1.2 8.9 1.7 1.7 1 1 0 1 1 1 0 Ninjurin EMP24_GP25L PF01105.19 EDP45454.1 - 9.8e-46 155.7 0.0 1.1e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GP41 PF00517.12 EDP45454.1 - 0.031 13.8 0.2 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Ninjurin PF04923.7 EDP45454.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Ninjurin DUF4519 PF15012.1 EDP45454.1 - 0.2 11.5 0.2 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Voltage_CLC PF00654.15 EDP45455.1 - 4.9e-75 252.7 28.0 1.2e-45 156.0 8.3 3.3 2 2 2 4 4 4 2 Voltage gated chloride channel CBS PF00571.23 EDP45455.1 - 9e-11 41.3 0.1 3.7e-07 29.8 0.1 2.7 2 0 0 2 2 2 2 CBS domain SAC3_GANP PF03399.11 EDP45456.1 - 5.7e-48 163.1 0.0 9.5e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DLIC PF05783.6 EDP45457.1 - 2.3e-23 82.5 0.2 1.7e-15 56.7 0.0 3.5 3 1 1 4 4 4 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 EDP45457.1 - 4.6e-05 23.4 0.4 0.066 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EDP45457.1 - 0.0062 17.0 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDP45457.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDP45457.1 - 0.085 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Dynamin family PPR_2 PF13041.1 EDP45458.1 - 5.1e-24 83.9 0.0 8.7e-06 25.6 0.0 8.5 8 2 2 10 10 10 4 PPR repeat family PPR PF01535.15 EDP45458.1 - 1.6e-19 68.4 0.0 0.03 14.3 0.0 11.8 14 0 0 14 14 14 4 PPR repeat PPR_3 PF13812.1 EDP45458.1 - 9e-19 66.1 32.5 0.22 11.9 0.0 14.5 16 0 0 16 16 16 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 EDP45458.1 - 2.5e-11 42.8 0.0 0.15 11.5 0.0 7.5 7 0 0 7 7 7 4 PPR repeat YEATS PF03366.11 EDP45459.1 - 2.2e-31 107.3 0.0 3.6e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 YEATS family SMK-1 PF04802.10 EDP45460.1 - 1.6e-53 181.1 5.1 3.3e-53 180.1 3.5 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Rcd1 PF04078.8 EDP45460.1 - 0.028 13.2 0.4 0.073 11.8 0.1 1.9 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like Gln-synt_C PF00120.19 EDP45461.1 - 4.7e-56 189.8 0.0 5.6e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EDP45461.1 - 2.6e-18 65.3 0.0 4.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain cNMP_binding PF00027.24 EDP45462.1 - 7.4e-42 141.0 0.2 2.1e-20 72.2 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EDP45462.1 - 3.3e-17 63.1 8.4 1.7e-11 44.4 2.1 3.1 3 0 0 3 3 3 2 Patatin-like phospholipase CPSF100_C PF13299.1 EDP45463.1 - 5e-25 88.5 0.1 8.4e-22 78.0 0.0 2.9 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EDP45463.1 - 2.1e-18 66.4 0.0 4.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EDP45463.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDP45463.1 - 0.0071 16.0 0.1 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Med18 PF09637.5 EDP45463.1 - 0.21 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Med18 protein Ribosomal_L3 PF00297.17 EDP45464.1 - 8.8e-38 130.1 0.4 2.9e-37 128.5 0.3 1.7 1 1 0 1 1 1 1 Ribosomal protein L3 DSPc PF00782.15 EDP45465.1 - 4.5e-30 103.9 0.0 1.6e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDP45465.1 - 1.5e-05 24.4 0.0 4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Cpn60_TCP1 PF00118.19 EDP45468.1 - 3.9e-121 405.0 2.2 6.2e-60 203.2 0.4 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family G_glu_transpept PF01019.16 EDP45469.1 - 7.7e-146 486.5 0.0 8.7e-146 486.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Reo_sigmaC PF04582.7 EDP45470.1 - 0.45 9.6 25.4 0.68 9.0 1.3 4.3 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EDP45470.1 - 0.84 8.2 55.3 3.7 6.1 12.0 3.8 2 1 0 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EDP45470.1 - 1.2 9.2 45.4 0.12 12.5 1.6 4.2 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ERM PF00769.14 EDP45470.1 - 1.7 8.1 70.1 1.3 8.4 25.7 4.2 2 1 2 4 4 4 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 EDP45470.1 - 1.7 8.5 69.1 0.039 13.7 8.9 4.4 2 1 2 4 4 4 0 Tropomyosin like ATG16 PF08614.6 EDP45470.1 - 3 7.6 65.3 2.2 8.0 0.3 4.4 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 EDP45470.1 - 4.9 6.5 47.2 0.52 9.7 5.1 5.8 3 1 4 7 7 7 0 B-cell receptor-associated protein 31-like NGP1NT PF08153.7 EDP45471.1 - 2.8e-43 146.9 0.0 2.8e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EDP45471.1 - 2.7e-19 69.2 0.0 1.5e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDP45471.1 - 8.4e-06 25.1 0.1 1.9e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EDP45471.1 - 0.00039 19.6 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EDP45471.1 - 0.00044 19.5 0.2 0.079 12.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDP45471.1 - 0.012 15.0 0.1 1.9 7.8 0.0 3.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDP45471.1 - 0.077 12.8 8.0 0.87 9.3 0.0 4.1 4 1 1 5 5 5 0 Dynamin family tRNA-synt_1d PF00750.14 EDP45472.1 - 5e-87 291.9 0.1 6.5e-87 291.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EDP45472.1 - 1.5e-19 70.0 0.5 5.9e-19 68.1 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Lzipper-MIP1 PF14389.1 EDP45473.1 - 3.3 7.8 10.9 0.065 13.3 0.4 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF3602 PF12223.3 EDP45474.1 - 7.8e-09 35.8 8.3 0.00033 20.9 1.6 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) BRCT PF00533.21 EDP45475.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain VHS PF00790.14 EDP45476.1 - 1.3e-40 138.2 0.4 1.4e-38 131.7 0.0 2.6 3 0 0 3 3 3 2 VHS domain GAT PF03127.9 EDP45476.1 - 2.7e-18 65.7 2.7 3.7e-18 65.3 0.9 2.0 2 0 0 2 2 2 1 GAT domain Macoilin PF09726.4 EDP45476.1 - 9 4.4 13.1 14 3.7 9.1 1.4 1 0 0 1 1 1 0 Transmembrane protein PPR_2 PF13041.1 EDP45477.1 - 1.7e-12 47.1 0.0 0.029 14.3 0.0 4.8 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EDP45477.1 - 2.4e-10 39.8 9.0 3.1 8.3 0.0 9.3 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 EDP45477.1 - 1.7e-07 30.7 0.3 0.72 9.9 0.0 6.3 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 EDP45477.1 - 0.00012 21.4 0.5 0.026 13.9 0.0 4.0 4 1 0 4 4 4 1 PPR repeat ECSIT PF06239.6 EDP45477.1 - 0.009 14.8 0.0 0.24 10.2 0.0 2.5 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway PIP5K PF01504.13 EDP45478.1 - 1.6e-62 210.9 0.1 3.1e-62 209.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EDP45478.1 - 3.6e-21 75.3 0.0 5.6e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EDP45478.1 - 3.4e-17 62.0 10.5 3.4e-17 62.0 7.3 2.3 2 0 0 2 2 2 1 FYVE zinc finger AAA PF00004.24 EDP45479.1 - 3.6e-44 150.1 0.0 5.9e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP45479.1 - 6.7e-08 32.7 0.0 9.7e-06 25.6 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 EDP45479.1 - 7.2e-08 32.2 0.1 3.1e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDP45479.1 - 1e-06 28.8 0.0 0.00024 21.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDP45479.1 - 1.2e-06 28.5 0.0 2.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDP45479.1 - 1.7e-05 23.9 0.0 3.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDP45479.1 - 5.2e-05 22.9 0.1 0.00014 21.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDP45479.1 - 0.00046 20.9 0.3 0.0013 19.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDP45479.1 - 0.00081 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EDP45479.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDP45479.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EDP45479.1 - 0.0017 17.4 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EDP45479.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDP45479.1 - 0.0033 16.6 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDP45479.1 - 0.0049 16.7 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDP45479.1 - 0.005 17.1 0.1 0.019 15.2 0.0 2.0 1 1 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EDP45479.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDP45479.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP45479.1 - 0.0077 15.7 0.1 0.037 13.4 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EDP45479.1 - 0.0086 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EDP45479.1 - 0.0089 15.6 0.0 0.037 13.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDP45479.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDP45479.1 - 0.012 14.7 0.1 0.045 12.8 0.0 1.9 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EDP45479.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EDP45479.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDP45479.1 - 0.024 14.0 0.2 0.079 12.3 0.1 1.8 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDP45479.1 - 0.033 13.8 0.0 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EDP45479.1 - 0.038 13.6 0.0 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EDP45479.1 - 0.054 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EDP45479.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EDP45479.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EDP45479.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EDP45479.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.7 2 1 0 2 2 1 0 AAA domain Clathrin PF00637.15 EDP45480.1 - 6.3e-204 667.7 25.7 5.9e-32 110.2 0.2 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EDP45480.1 - 1.9e-31 107.7 0.1 5.3e-31 106.3 0.1 1.9 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EDP45480.1 - 3e-28 96.1 0.5 0.0011 19.0 0.0 7.8 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin-link PF09268.5 EDP45480.1 - 5.5e-10 38.0 1.5 7.9e-10 37.5 0.1 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EDP45480.1 - 3.2e-06 26.2 3.9 0.079 11.7 0.0 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.23 EDP45480.1 - 3.2e-05 23.3 2.2 22 4.8 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDP45480.1 - 0.0033 17.2 5.4 28 4.9 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDP45480.1 - 0.018 14.9 13.9 8.8 6.3 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Asparaginase_2 PF01112.13 EDP45480.1 - 0.035 12.8 0.0 0.082 11.6 0.0 1.5 1 0 0 1 1 1 0 Asparaginase AMP-binding_C_2 PF14535.1 EDP45480.1 - 0.069 13.1 1.8 8.2 6.5 0.0 3.9 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain TPR_14 PF13428.1 EDP45480.1 - 0.21 12.3 22.6 40 5.2 0.1 10.1 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDP45480.1 - 0.71 9.8 10.9 29 4.7 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Vps5 PF09325.5 EDP45481.1 - 0.0016 17.7 1.4 0.54 9.4 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EDP45481.1 - 0.0077 15.7 0.5 0.018 14.5 0.1 1.8 1 1 1 2 2 2 1 BAR domain PX PF00787.19 EDP45482.1 - 5.6e-21 74.4 0.2 8.3e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 PX domain ATP-grasp_4 PF13535.1 EDP45482.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain FYVE PF01363.16 EDP45483.1 - 3.3e-06 26.9 5.9 3.3e-06 26.9 4.1 2.4 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.1 EDP45483.1 - 3.1e-05 23.5 9.7 3.1e-05 23.5 6.7 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDP45483.1 - 4.2e-05 23.4 21.2 0.011 15.6 7.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDP45483.1 - 0.00035 20.2 11.6 0.00035 20.2 8.0 3.5 2 2 1 3 3 3 1 zinc-RING finger domain Rtf2 PF04641.7 EDP45483.1 - 0.00037 19.7 1.8 0.00037 19.7 1.3 2.9 1 1 2 3 3 3 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 EDP45483.1 - 0.00058 19.6 2.0 0.00058 19.6 1.4 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EDP45483.1 - 0.0025 17.4 10.1 0.0025 17.4 7.0 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DNA_RNApol_7kD PF03604.8 EDP45483.1 - 0.012 15.0 4.1 0.021 14.2 0.1 2.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_2 PF13639.1 EDP45483.1 - 0.013 15.3 22.7 0.024 14.4 8.2 2.7 2 1 1 3 3 3 0 Ring finger domain Zn-ribbon_8 PF09723.5 EDP45483.1 - 0.078 12.9 6.1 0.6 10.1 0.7 3.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_UBOX PF13445.1 EDP45483.1 - 0.083 12.6 13.3 0.051 13.3 5.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Pellino PF04710.9 EDP45483.1 - 0.16 10.5 2.4 0.15 10.6 0.5 1.8 2 0 0 2 2 2 0 Pellino zf-CHY PF05495.7 EDP45483.1 - 6.8 6.9 14.6 51 4.1 4.7 3.4 2 1 1 3 3 3 0 CHY zinc finger zf-RING_4 PF14570.1 EDP45483.1 - 6.8 6.3 16.8 0.74 9.4 0.3 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain ETC_C1_NDUFA5 PF04716.9 EDP45484.1 - 3.9e-16 58.2 0.7 6.1e-16 57.6 0.5 1.5 1 1 0 1 1 1 1 ETC complex I subunit conserved region PaaSYMP PF14738.1 EDP45484.1 - 0.075 12.7 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Sds3 PF08598.6 EDP45485.1 - 2.9e-10 40.0 0.1 3.8e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Sds3-like Orn_Arg_deC_N PF02784.11 EDP45486.1 - 9.6e-70 234.6 0.0 1.6e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EDP45486.1 - 6.3e-31 106.4 0.0 9.9e-31 105.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Glyco_transf_41 PF13844.1 EDP45486.1 - 0.046 11.6 0.0 0.066 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 Zn_clus PF00172.13 EDP45487.1 - 1.8e-05 24.5 8.3 3.3e-05 23.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AFT PF08731.6 EDP45487.1 - 0.94 9.6 3.8 0.53 10.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor AFT Pkinase PF00069.20 EDP45488.1 - 1.6e-68 230.6 0.0 2.7e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45488.1 - 9.3e-34 116.6 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDP45488.1 - 0.0098 15.6 0.0 0.0098 15.6 0.0 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family Complex1_LYR_1 PF13232.1 EDP45489.1 - 3.1e-23 81.7 0.4 4.3e-23 81.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDP45489.1 - 5e-10 39.0 4.4 8.3e-10 38.3 2.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) UPRTase PF14681.1 EDP45490.1 - 6.7e-39 133.2 0.0 7.1e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EDP45490.1 - 4.6e-05 23.1 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Rxt3 PF08642.5 EDP45491.1 - 1.1e-20 73.9 0.0 2.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EDP45491.1 - 0.001 19.0 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 LCCL domain ESCRT-II PF05871.7 EDP45492.1 - 3.9e-33 114.3 0.0 7.2e-33 113.4 0.0 1.4 1 1 0 1 1 1 1 ESCRT-II complex subunit WD40 PF00400.27 EDP45493.1 - 1.4e-28 97.7 0.1 6e-09 35.4 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Macoilin PF09726.4 EDP45493.1 - 0.99 7.6 7.9 1.6 6.9 5.5 1.3 1 0 0 1 1 1 0 Transmembrane protein LSM PF01423.17 EDP45494.1 - 7.9e-13 47.7 0.0 1.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain CDC14 PF08045.6 EDP45495.1 - 2.7e-16 59.4 0.0 3.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component UAA PF08449.6 EDP45496.1 - 6.9e-15 54.7 21.5 2.4e-10 39.8 3.2 2.1 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 EDP45496.1 - 4.1e-12 46.0 4.5 4.1e-12 46.0 3.1 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDP45496.1 - 0.00035 20.6 8.3 0.00035 20.6 5.7 2.8 2 1 0 2 2 2 1 EamA-like transporter family ABC_membrane_2 PF06472.10 EDP45497.1 - 2.6e-92 308.9 7.1 3.5e-92 308.5 4.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDP45497.1 - 4.8e-16 59.3 0.0 1.2e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 EDP45497.1 - 0.0019 17.2 0.1 0.0053 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_21 PF13304.1 EDP45497.1 - 0.0051 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDP45497.1 - 0.015 16.0 0.0 0.052 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EDP45497.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDP45497.1 - 0.033 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 EDP45497.1 - 0.034 13.3 0.0 0.071 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EDP45497.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EDP45497.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDP45497.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EDP45497.1 - 0.042 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EDP45497.1 - 0.14 11.9 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EDP45497.1 - 0.16 12.3 0.0 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EDP45497.1 - 0.19 10.9 0.0 9.8 5.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zn_clus PF00172.13 EDP45500.1 - 8.4e-09 35.2 9.1 1.5e-08 34.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_channel_TID PF07941.6 EDP45500.1 - 0.027 14.6 2.9 0.027 14.6 2.0 2.8 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain PAT1 PF09770.4 EDP45500.1 - 0.14 10.3 7.0 0.16 10.1 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L23 PF00276.15 EDP45503.1 - 6.6e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 NIF PF03031.13 EDP45504.1 - 3.5e-50 169.7 0.0 8.5e-50 168.5 0.0 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.20 EDP45505.1 - 8.4e-57 192.2 0.0 1.1e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDP45505.1 - 1.1e-27 96.7 0.0 1.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDP45505.1 - 7.4e-06 25.1 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDP45505.1 - 0.015 15.0 0.0 0.056 13.1 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDP45505.1 - 0.23 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2340 PF10209.4 EDP45506.1 - 2.1e-34 118.2 0.0 2.4e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PXA PF02194.10 EDP45507.1 - 3e-19 69.3 0.2 2.9e-09 36.7 0.1 2.7 1 1 1 2 2 2 2 PXA domain Nexin_C PF08628.7 EDP45507.1 - 3e-06 27.3 0.1 8e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal XPG_I PF00867.13 EDP45508.1 - 9e-25 86.5 0.0 1.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDP45508.1 - 2.8e-12 46.7 0.0 6.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDP45508.1 - 6.6e-05 22.5 0.0 0.00028 20.4 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing NDUF_B8 PF05821.6 EDP45509.1 - 4.9e-06 26.3 0.1 7.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Metallophos PF00149.23 EDP45510.1 - 2.5e-36 124.9 0.3 3.2e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 EDP45510.1 - 0.019 14.0 0.2 0.037 13.0 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MCM PF00493.18 EDP45511.1 - 5e-139 462.7 0.0 7.5e-139 462.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EDP45511.1 - 3.4e-31 108.3 27.1 3.4e-31 108.3 18.8 2.3 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EDP45511.1 - 1.4e-18 67.5 0.1 4.9e-17 62.5 0.0 2.6 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDP45511.1 - 1.5e-08 34.0 0.0 3.8e-07 29.4 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDP45511.1 - 5.6e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDP45511.1 - 0.0017 17.9 0.0 0.01 15.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDP45511.1 - 0.0069 15.8 0.1 0.066 12.6 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EDP45511.1 - 0.029 14.5 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1931 PF09123.6 EDP45511.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) ABC2_membrane PF01061.19 EDP45512.1 - 8.3e-81 270.1 56.0 2e-43 148.0 15.9 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EDP45512.1 - 3.8e-41 140.5 0.0 1e-18 67.9 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EDP45512.1 - 6.1e-25 86.8 7.1 6e-22 77.2 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EDP45512.1 - 4.6e-10 39.4 0.2 3.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EDP45512.1 - 3.5e-08 33.0 0.5 0.00012 21.5 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDP45512.1 - 3.9e-07 30.2 0.0 0.0081 16.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDP45512.1 - 2.3e-06 27.7 1.0 0.00073 19.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EDP45512.1 - 7.9e-06 25.4 0.8 0.0037 16.7 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EDP45512.1 - 2.8e-05 23.3 0.0 0.00019 20.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDP45512.1 - 8.2e-05 23.4 0.0 0.052 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDP45512.1 - 0.00015 22.1 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDP45512.1 - 0.00023 20.6 1.1 0.013 15.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EDP45512.1 - 0.00053 19.6 0.1 0.32 10.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EDP45512.1 - 0.00055 19.5 0.5 0.096 12.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EDP45512.1 - 0.00068 19.6 0.0 0.95 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDP45512.1 - 0.00086 19.0 0.4 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain ABC2_membrane_3 PF12698.2 EDP45512.1 - 0.0018 17.4 56.5 0.0032 16.5 17.0 3.7 3 1 2 5 5 4 2 ABC-2 family transporter protein AAA_28 PF13521.1 EDP45512.1 - 0.0031 17.4 0.1 0.99 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP45512.1 - 0.0042 16.9 0.1 0.68 9.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDP45512.1 - 0.0047 16.4 0.2 2.1 7.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 EDP45512.1 - 0.01 15.0 0.0 0.31 10.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EDP45512.1 - 0.035 13.6 0.3 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDP45512.1 - 0.037 14.5 0.0 2.8 8.4 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA PF00004.24 EDP45512.1 - 0.042 14.0 0.1 6.8 6.9 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EDP45512.1 - 0.045 13.3 0.1 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDP45512.1 - 0.048 12.7 0.0 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EDP45512.1 - 0.048 13.6 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EDP45512.1 - 0.049 13.1 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EDP45512.1 - 0.079 12.6 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EDP45512.1 - 0.079 12.3 0.2 4.4 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EDP45512.1 - 0.14 11.6 0.5 9.1 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EDP45512.1 - 0.18 10.6 0.1 13 4.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 EDP45512.1 - 0.21 10.5 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EDP45512.1 - 0.23 11.7 0.1 0.88 9.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC2_membrane PF01061.19 EDP45513.1 - 1.3e-82 276.0 52.2 1.4e-42 145.2 10.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EDP45513.1 - 5.9e-37 127.0 0.0 1.9e-17 63.8 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EDP45513.1 - 1e-22 79.7 0.3 5.2e-19 67.8 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EDP45513.1 - 6.2e-14 51.8 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EDP45513.1 - 8.3e-07 28.3 33.0 1.9e-06 27.1 6.1 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EDP45513.1 - 1e-06 28.2 0.1 0.00068 19.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDP45513.1 - 4e-06 26.9 0.6 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EDP45513.1 - 1.6e-05 24.1 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDP45513.1 - 0.00015 21.9 0.1 0.045 13.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EDP45513.1 - 0.0003 20.2 0.1 0.019 14.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EDP45513.1 - 0.00088 18.7 1.3 0.02 14.3 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EDP45513.1 - 0.0011 19.8 0.0 0.26 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDP45513.1 - 0.0016 18.0 0.6 0.14 11.8 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EDP45513.1 - 0.0017 18.0 0.1 2.8 7.7 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_21 PF13304.1 EDP45513.1 - 0.0019 18.2 0.0 1.2 9.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EDP45513.1 - 0.0021 18.3 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDP45513.1 - 0.0071 16.0 0.1 0.43 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EDP45513.1 - 0.01 15.0 0.0 0.4 9.8 0.0 3.0 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EDP45513.1 - 0.018 14.4 0.3 4 6.8 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Miro PF08477.8 EDP45513.1 - 0.022 15.2 0.0 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EDP45513.1 - 0.024 14.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDP45513.1 - 0.025 13.6 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EDP45513.1 - 0.031 14.4 0.1 7.8 6.7 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EDP45513.1 - 0.074 13.0 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EDP45513.1 - 0.081 12.4 0.4 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EDP45513.1 - 0.096 12.6 0.1 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EDP45513.1 - 0.2 11.2 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EDP45513.1 - 0.65 10.2 0.0 1.5 9.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 EDP45514.1 - 3.5e-14 52.9 4.6 5.2e-14 52.4 0.6 2.6 2 2 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EDP45514.1 - 9.1e-11 41.2 4.6 9.1e-11 41.2 3.2 2.6 3 0 0 3 3 3 1 SNARE domain DUF948 PF06103.6 EDP45514.1 - 0.013 15.3 3.2 0.3 10.9 0.8 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.11 EDP45514.1 - 0.058 13.4 6.4 1.9 8.5 1.6 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein HisKA_3 PF07730.8 EDP45514.1 - 0.059 13.7 10.2 0.2 12.0 1.8 2.9 3 1 0 3 3 3 0 Histidine kinase Flg_hook PF02120.11 EDP45514.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.6 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Tropomyosin_1 PF12718.2 EDP45514.1 - 0.37 10.6 2.6 4.4 7.1 0.1 2.3 2 1 0 2 2 2 0 Tropomyosin like Reo_sigmaC PF04582.7 EDP45514.1 - 0.81 8.8 6.6 0.51 9.4 1.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 EDP45514.1 - 0.91 10.0 6.2 5.3 7.5 0.3 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Gon7 PF08738.5 EDP45514.1 - 3.1 7.8 6.2 2.7 8.0 0.1 2.4 2 1 0 2 2 2 0 Gon7 family Baculo_PEP_C PF04513.7 EDP45514.1 - 7.2 6.4 10.6 9 6.1 3.0 2.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UDP-g_GGTase PF06427.6 EDP45515.1 - 1.5e-41 142.0 0.0 3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase SNARE_assoc PF09335.6 EDP45517.1 - 1.7e-20 73.4 5.0 1.7e-20 73.4 3.5 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein GCV_T_C PF08669.6 EDP45518.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 EDP45518.1 - 0.0023 17.3 0.0 0.0056 16.0 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain LtrA PF06772.6 EDP45519.1 - 1.1e-14 54.1 20.9 6.8e-08 31.8 0.3 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) 5_nucleotid_C PF02872.13 EDP45520.1 - 5.5e-30 104.4 0.0 8.2e-29 100.5 0.0 2.1 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain HMG_box PF00505.14 EDP45521.1 - 9.7e-21 73.8 12.5 1.2e-14 54.3 1.4 2.6 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EDP45521.1 - 4.2e-17 62.2 10.4 1.9e-13 50.5 2.0 2.2 2 0 0 2 2 2 2 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EDP45521.1 - 9.8e-05 21.9 3.3 0.0033 16.9 0.1 2.2 2 0 0 2 2 2 2 Toluene tolerance, Ttg2 DUF1413 PF07205.6 EDP45521.1 - 0.0032 16.9 0.3 0.026 14.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1413) PEPcase_2 PF14010.1 EDP45521.1 - 0.01 14.1 0.6 0.12 10.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase JmjC PF02373.17 EDP45521.1 - 0.04 14.1 1.0 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF2489 PF10675.4 EDP45521.1 - 0.063 12.9 1.3 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Apolipoprotein PF01442.13 EDP45521.1 - 0.074 12.5 2.7 1.3 8.5 1.9 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4509 PF14970.1 EDP45521.1 - 0.095 12.3 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) PGI PF00342.14 EDP45522.1 - 2.4e-210 699.0 0.0 2.7e-210 698.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase KH_1 PF00013.24 EDP45523.1 - 3.7e-06 26.4 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDP45523.1 - 0.02 14.5 0.0 0.073 12.7 0.0 2.0 1 0 0 1 1 1 0 KH domain Pyocin_S PF06958.7 EDP45523.1 - 0.084 13.2 7.4 0.093 13.0 3.4 2.1 1 1 1 2 2 2 0 S-type Pyocin DUF605 PF04652.11 EDP45523.1 - 2.4 7.4 12.4 2.9 7.2 8.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1744 PF08490.7 EDP45526.1 - 2.3e-87 293.1 0.0 4.7e-59 199.9 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EDP45526.1 - 8.6e-63 212.1 0.0 1.4e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EDP45526.1 - 2.8e-20 72.5 0.0 1.1e-19 70.6 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EDP45526.1 - 1.3e-09 37.8 0.0 3.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EDP45526.1 - 0.0004 20.2 0.2 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily KIAA1328 PF15369.1 EDP45526.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 ParA PF10609.4 EDP45527.1 - 9.2e-35 118.3 0.1 1.6e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDP45527.1 - 3e-12 46.3 0.0 5.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EDP45527.1 - 0.00012 21.1 0.3 0.00025 20.1 0.1 1.7 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EDP45527.1 - 0.00021 20.7 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EDP45527.1 - 0.0061 16.5 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EDP45527.1 - 0.0083 15.3 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 EDP45527.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 EDP45527.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein ArgK PF03308.11 EDP45527.1 - 0.028 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein MipZ PF09140.6 EDP45527.1 - 0.036 13.1 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 EDP45527.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PcrB PF01884.12 EDP45527.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 PcrB family NACHT PF05729.7 EDP45527.1 - 0.13 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EDP45527.1 - 0.14 11.6 0.1 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Beach PF02138.13 EDP45528.1 - 8.7e-102 340.1 0.0 1.2e-101 339.7 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EDP45528.1 - 7.4e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EDP45528.1 - 3.2e-05 23.6 5.1 7.8e-05 22.4 0.3 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat FYVE_2 PF02318.11 EDP45528.1 - 0.00017 21.4 3.7 0.00036 20.4 2.6 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Laminin_G_3 PF13385.1 EDP45528.1 - 0.00055 20.1 0.0 0.00099 19.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.16 EDP45528.1 - 0.0089 15.9 5.8 0.023 14.5 4.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger RRM_1 PF00076.17 EDP45529.1 - 2.1e-10 40.0 0.0 3.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDP45529.1 - 8.1e-09 35.2 0.3 1.6e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDP45529.1 - 8.5e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EDP45529.1 - 3.9e-06 27.2 2.4 6.5e-06 26.5 1.7 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Uds1 PF15456.1 EDP45529.1 - 0.007 16.3 0.2 0.0095 15.9 0.1 1.1 1 0 0 1 1 1 1 Up-regulated During Septation DUF935 PF06074.7 EDP45529.1 - 0.077 11.7 2.2 0.091 11.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) CXCL17 PF15211.1 EDP45529.1 - 0.1 13.0 0.7 0.17 12.3 0.5 1.3 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 ARS2 PF04959.8 EDP45529.1 - 0.2 11.8 2.0 0.44 10.7 0.8 1.7 1 1 1 2 2 2 0 Arsenite-resistance protein 2 UcrQ PF02939.11 EDP45530.1 - 4.9e-24 83.9 1.9 5.8e-24 83.7 1.3 1.0 1 0 0 1 1 1 1 UcrQ family DUF2296 PF10058.4 EDP45531.1 - 2.7e-17 62.2 0.8 4.6e-14 51.8 0.0 2.4 1 1 1 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) NAD_kinase PF01513.16 EDP45532.1 - 1.8e-38 131.9 0.0 2.2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Histone PF00125.19 EDP45533.1 - 1.3e-30 105.3 0.4 2e-30 104.7 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDP45533.1 - 9e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDP45533.1 - 0.0074 16.3 0.1 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EDP45533.1 - 0.011 15.0 0.9 0.021 14.0 0.6 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDP45533.1 - 0.017 14.8 0.1 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 EDP45534.1 - 1.6e-38 129.2 6.1 5.2e-08 32.4 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EDP45534.1 - 7.2e-08 32.3 0.2 2.5e-05 24.0 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDP45534.1 - 7.4 4.2 6.3 17 3.0 0.5 2.9 1 1 1 2 2 2 0 IKI3 family GMP_synt_C PF00958.17 EDP45535.1 - 3.6e-39 132.3 0.1 7.5e-39 131.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EDP45535.1 - 3.7e-38 130.9 0.0 7.7e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EDP45535.1 - 9.9e-12 44.2 0.1 2.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EDP45535.1 - 1.2e-09 37.9 0.0 2.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EDP45535.1 - 0.0003 19.4 0.2 0.00064 18.3 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EDP45535.1 - 0.00044 19.7 0.0 0.001 18.6 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EDP45535.1 - 0.00088 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EDP45535.1 - 0.0012 18.2 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EDP45535.1 - 0.019 13.9 0.1 0.046 12.7 0.1 1.6 1 0 0 1 1 1 0 Arginosuccinate synthase DUF2392 PF10288.4 EDP45535.1 - 0.087 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) WD40 PF00400.27 EDP45536.1 - 1.5e-23 81.7 5.4 7e-08 32.0 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.15 EDP45537.1 - 8.3e-26 90.1 0.0 1.2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDP45537.1 - 0.0006 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDP45537.1 - 0.0046 16.1 0.0 0.016 14.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Rnk_N PF14760.1 EDP45537.1 - 0.029 14.4 2.5 0.25 11.4 0.2 2.7 2 0 0 2 2 2 0 Rnk N-terminus SNARE PF05739.14 EDP45538.1 - 7.4e-18 64.0 0.5 7.4e-18 64.0 0.4 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EDP45538.1 - 8.7e-14 51.5 1.3 8.7e-14 51.5 0.9 2.5 2 1 0 2 2 2 1 Syntaxin zf-C4H2 PF10146.4 EDP45538.1 - 0.0013 18.7 3.0 0.38 10.7 0.5 2.1 1 1 1 2 2 2 2 Zinc finger-containing protein DUF1664 PF07889.7 EDP45538.1 - 0.029 14.1 2.7 0.33 10.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EDP45538.1 - 0.071 13.0 0.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EDP45538.1 - 0.078 12.8 6.7 2.3 8.0 0.2 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.11 EDP45538.1 - 0.091 12.8 10.1 0.034 14.2 1.7 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Prominin PF05478.6 EDP45538.1 - 0.26 8.7 6.2 0.19 9.1 0.1 2.0 2 0 0 2 2 2 0 Prominin DUF148 PF02520.12 EDP45538.1 - 0.3 10.8 8.7 4 7.2 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF148 FliD_N PF02465.13 EDP45538.1 - 0.34 11.3 3.7 4.2 7.7 0.0 3.3 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus T2SF PF00482.18 EDP45538.1 - 0.5 10.2 2.4 1.2 9.0 0.2 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F LXG PF04740.7 EDP45538.1 - 0.91 9.2 7.1 3 7.5 0.4 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily SlyX PF04102.7 EDP45538.1 - 1.4 9.3 5.3 3.1 8.2 0.1 3.3 2 2 0 2 2 2 0 SlyX Exonuc_VII_L PF02601.10 EDP45538.1 - 2.1 7.4 11.6 7.5 5.6 8.1 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.6 EDP45538.1 - 2.4 7.9 11.6 1.7 8.4 4.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spectrin PF00435.16 EDP45538.1 - 3.5 7.9 7.3 4.4 7.6 0.3 3.0 2 1 1 3 3 3 0 Spectrin repeat Sdh_cyt PF01127.17 EDP45539.1 - 7.3e-20 71.0 2.9 9.5e-20 70.6 2.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Spc97_Spc98 PF04130.8 EDP45540.1 - 8.1e-103 344.5 2.5 1.1e-102 344.1 1.7 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family TP_methylase PF00590.15 EDP45541.1 - 1.3e-37 129.6 0.3 2.6e-37 128.5 0.2 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EDP45541.1 - 5.8e-13 48.9 0.0 1.2e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EDP45541.1 - 6.7e-06 25.3 1.0 4e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EDP45541.1 - 0.0013 17.6 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SAM_decarbox PF01536.11 EDP45542.1 - 9.8e-84 280.8 0.0 7.4e-83 277.9 0.0 2.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Peptidase_M16_C PF05193.16 EDP45543.1 - 7.5e-17 61.5 0.0 4.5e-13 49.2 0.0 3.0 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDP45543.1 - 1.9e-07 30.9 0.1 6.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Xan_ur_permease PF00860.15 EDP45544.1 - 9.1e-19 67.1 23.3 1.2e-17 63.5 16.2 2.3 1 1 0 1 1 1 1 Permease family DUF2376 PF09550.5 EDP45544.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical phage protein (DUF2376) Herpes_UL56 PF04534.7 EDP45544.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein Asp PF00026.18 EDP45545.1 - 4.2e-27 95.2 0.1 1.3e-26 93.6 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDP45545.1 - 0.00096 19.6 0.0 0.31 11.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EDP45545.1 - 0.081 12.8 0.0 1.9 8.3 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Ricin_B_lectin PF00652.17 EDP45547.1 - 0.0026 17.7 0.1 2.5 8.1 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain UPF0506 PF11703.3 EDP45548.1 - 0.007 16.3 2.4 0.014 15.3 1.6 1.4 1 0 0 1 1 1 1 UPF0506 SHP PF03579.8 EDP45548.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.5 2 0 0 2 2 2 0 Small hydrophobic protein zf-primase PF09329.6 EDP45548.1 - 0.3 10.7 2.9 0.41 10.2 0.8 2.0 2 0 0 2 2 2 0 Primase zinc finger EB PF01683.13 EDP45548.1 - 8.8 6.4 9.0 13 5.9 1.9 2.8 1 1 1 2 2 2 0 EB module Chorismate_bind PF00425.13 EDP45549.1 - 8e-88 294.0 0.0 1.1e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EDP45549.1 - 1.3e-27 96.4 0.0 3.6e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.3 EDP45550.1 - 4.5e-46 157.1 0.7 1.9e-45 155.1 0.5 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EDP45550.1 - 9.5e-33 111.6 1.2 5.2e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 Surp module TFIIA PF03153.8 EDP45550.1 - 0.029 14.2 8.7 0.052 13.4 6.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Di19 PF05605.7 EDP45550.1 - 0.095 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Macoilin PF09726.4 EDP45550.1 - 1.6 6.8 6.2 2.4 6.3 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PalH PF08733.5 EDP45551.1 - 0.036 12.9 13.0 0.0049 15.7 5.2 1.8 1 1 1 2 2 2 0 PalH/RIM21 ADK PF00406.17 EDP45552.1 - 1.9e-42 144.7 0.0 2.2e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDP45552.1 - 3.2e-13 49.0 0.0 7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EDP45552.1 - 7e-09 36.5 0.0 1.6e-08 35.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EDP45552.1 - 7.8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDP45552.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EDP45552.1 - 0.00076 19.7 0.0 0.0017 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDP45552.1 - 0.053 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDP45552.1 - 0.097 12.8 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EDP45553.1 - 1.4e-276 919.3 0.0 1.5e-276 919.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TEX13 PF15186.1 EDP45553.1 - 0.11 12.0 1.7 0.24 10.9 1.2 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Cep57_MT_bd PF06657.8 EDP45553.1 - 0.5 10.3 3.4 3.1 7.7 1.6 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 VCBS PF13517.1 EDP45554.1 - 2.2e-18 66.3 6.0 0.00061 20.1 0.2 5.1 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EDP45554.1 - 1.1e-15 56.7 1.5 0.00049 19.7 0.0 5.7 5 0 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EDP45554.1 - 7.1e-05 22.3 0.9 3.1 7.2 0.0 4.5 4 1 1 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region Apt1 PF10351.4 EDP45555.1 - 1e-76 258.6 0.0 1.5e-76 258.0 0.0 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EDP45555.1 - 1e-39 136.2 1.8 3.3e-39 134.6 1.2 1.8 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EDP45555.1 - 6.1e-36 123.7 0.0 1.2e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EDP45555.1 - 9.7e-25 87.1 0.0 5.6e-24 84.6 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EDP45555.1 - 4.6e-07 30.2 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain AT_hook PF02178.14 EDP45556.1 - 0.021 14.4 1.9 0.021 14.4 1.3 3.9 3 0 0 3 3 3 0 AT hook motif Mif2_N PF15624.1 EDP45556.1 - 0.48 11.0 18.3 0.081 13.5 6.1 3.3 1 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal tRNA_Me_trans PF03054.11 EDP45557.1 - 2.7e-89 299.2 0.0 3e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Ras PF00071.17 EDP45559.1 - 2.9e-52 176.3 0.0 3.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDP45559.1 - 2.8e-16 60.0 0.0 5.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDP45559.1 - 3e-06 26.5 0.0 4.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Asn_synthase PF00733.16 EDP45562.1 - 1.9e-66 224.1 0.4 6.2e-66 222.4 0.2 1.9 2 1 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 EDP45562.1 - 5.7e-38 129.4 0.0 9.7e-38 128.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDP45562.1 - 6.5e-30 103.8 0.0 5.1e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDP45562.1 - 3.4e-08 32.9 0.0 5.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EDP45562.1 - 4.9e-06 25.4 0.0 0.28 9.8 0.0 3.2 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EDP45562.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 EDP45562.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC WD40 PF00400.27 EDP45563.1 - 4.6e-11 42.1 6.2 0.0045 16.8 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EDP45563.1 - 0.029 14.6 0.2 37 4.7 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain Hira PF07569.6 EDP45563.1 - 0.18 11.0 0.4 0.53 9.4 0.0 2.0 3 0 0 3 3 3 0 TUP1-like enhancer of split Mog1 PF04603.7 EDP45564.1 - 4.8e-28 97.8 0.1 5.8e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein AlaDh_PNT_N PF05222.10 EDP45565.1 - 4e-27 94.8 0.0 5.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EDP45565.1 - 1.2e-06 28.2 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_1 PF00175.16 EDP45566.1 - 1.2e-27 96.6 0.0 3e-27 95.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDP45566.1 - 1.3e-24 86.1 0.1 3.4e-24 84.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDP45566.1 - 8.4e-06 25.7 0.0 8.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Abhydrolase_3 PF07859.8 EDP45567.1 - 4e-44 150.7 0.0 2.6e-34 118.6 0.0 3.3 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EDP45567.1 - 2.3e-09 36.4 0.0 2.3e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDP45567.1 - 0.00017 21.3 0.0 0.00048 19.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDP45567.1 - 0.017 13.6 0.1 0.028 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EDP45567.1 - 0.044 13.0 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EDP45567.1 - 0.078 11.6 0.2 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.11 EDP45567.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Shugoshin_C PF07557.6 EDP45569.1 - 2.5e-09 36.4 3.6 2.5e-09 36.4 2.5 4.3 3 1 1 4 4 4 1 Shugoshin C terminus Smg4_UPF3 PF03467.10 EDP45571.1 - 2.6e-24 86.1 0.1 2.6e-24 86.1 0.1 1.9 2 1 0 2 2 2 1 Smg-4/UPF3 family DUF605 PF04652.11 EDP45571.1 - 0.9 8.8 40.2 1.3 8.3 27.9 1.2 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EDP45571.1 - 2.1 6.5 35.1 2.6 6.1 24.3 1.1 1 0 0 1 1 1 0 Transmembrane protein AvrE PF11725.3 EDP45571.1 - 2.1 5.2 25.7 2.5 5.0 17.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Actin PF00022.14 EDP45572.1 - 1.5e-30 105.9 0.0 3.4e-30 104.7 0.0 1.5 1 1 0 1 1 1 1 Actin LRR_6 PF13516.1 EDP45573.1 - 7.4e-05 22.4 0.1 3.6 7.9 0.0 4.9 5 1 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EDP45573.1 - 0.00084 19.1 0.2 37 5.1 0.0 4.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 EDP45573.1 - 0.014 15.3 0.7 13 6.3 0.1 4.2 5 1 0 5 5 5 0 Leucine Rich Repeat MIF4G PF02854.14 EDP45574.1 - 8.5e-28 97.1 0.0 5.2e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EDP45574.1 - 2.4e-27 94.8 0.2 5.5e-27 93.7 0.1 1.7 1 0 0 1 1 1 1 MA3 domain ECR1_N PF14382.1 EDP45575.1 - 1.2e-08 34.0 0.1 2.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EDP45575.1 - 0.00031 20.6 0.1 0.0018 18.1 0.1 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 UQ_con PF00179.21 EDP45576.1 - 1.4e-15 56.9 0.1 1.5e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDP45576.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Thiolase_N PF00108.18 EDP45577.1 - 9.9e-94 313.2 0.2 1.6e-93 312.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDP45577.1 - 1.8e-33 114.5 1.5 6.9e-33 112.6 0.4 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDP45577.1 - 4.5e-06 26.3 5.2 5.8e-06 25.9 0.2 2.9 3 1 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EDP45577.1 - 0.01 15.4 0.6 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AAA PF00004.24 EDP45579.1 - 1.1e-40 138.8 0.0 2.3e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDP45579.1 - 1.2e-05 25.4 0.0 0.0011 19.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDP45579.1 - 3.1e-05 23.7 0.1 0.00019 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EDP45579.1 - 0.00045 19.2 0.0 0.00088 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EDP45579.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDP45579.1 - 0.0014 18.6 0.0 0.016 15.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDP45579.1 - 0.0029 18.4 0.6 0.0067 17.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EDP45579.1 - 0.0063 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EDP45579.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDP45579.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDP45579.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EDP45579.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDP45579.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EDP45579.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EDP45579.1 - 0.036 13.7 0.0 4.8 6.8 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 EDP45579.1 - 0.042 13.4 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDP45579.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDP45579.1 - 0.056 12.8 0.3 0.27 10.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 EDP45579.1 - 0.059 12.0 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EDP45579.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDP45579.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4164 PF13747.1 EDP45579.1 - 0.089 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Sigma54_activat PF00158.21 EDP45579.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EDP45579.1 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 EDP45580.1 - 8.8e-109 362.0 0.0 1.3e-108 361.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDP45580.1 - 7.3e-23 81.1 0.5 1.6e-22 80.0 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDP45580.1 - 4e-14 52.5 2.3 1.3e-13 50.9 1.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DHBP_synthase PF00926.14 EDP45581.1 - 8.8e-53 178.4 0.0 1.1e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mitofilin PF09731.4 EDP45582.1 - 6.7e-91 305.7 14.2 7.9e-91 305.4 9.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ribosomal_L31e PF01198.14 EDP45582.1 - 0.086 12.5 0.2 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L31e Tape_meas_lam_C PF09718.5 EDP45582.1 - 0.2 11.5 2.8 0.26 11.2 0.2 2.5 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1104 PF06518.6 EDP45582.1 - 0.22 11.6 8.2 6.2 7.0 1.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF4404 PF14357.1 EDP45582.1 - 6.7 7.2 15.1 0.096 13.1 1.2 3.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4404) IMS PF00817.15 EDP45583.1 - 5e-35 120.4 0.2 1.1e-34 119.3 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EDP45583.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EDP45583.1 - 1.1e-08 35.1 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDP45583.1 - 0.00021 21.0 0.1 0.00081 19.2 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain DUF4414 PF14377.1 EDP45583.1 - 0.001 18.9 3.3 0.016 15.1 0.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) DUF1805 PF08827.6 EDP45583.1 - 0.046 13.5 0.0 0.54 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) ADK PF00406.17 EDP45584.1 - 3.5e-59 199.0 0.1 4.2e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDP45584.1 - 4.8e-14 51.7 0.0 1.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EDP45584.1 - 3e-08 33.6 0.0 6.4e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDP45584.1 - 5.2e-06 25.7 0.0 8.3e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EDP45584.1 - 0.00036 20.8 0.0 0.00097 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDP45584.1 - 0.0037 18.0 0.0 0.0086 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDP45584.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EDP45584.1 - 0.024 14.8 0.1 0.057 13.6 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EDP45584.1 - 0.04 13.3 0.1 4.2 6.7 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase ParA PF10609.4 EDP45585.1 - 3.2e-32 110.2 0.0 5.3e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDP45585.1 - 4.3e-12 45.8 0.1 2.4e-11 43.4 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EDP45585.1 - 7.9e-06 25.1 1.1 0.0002 20.4 0.3 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EDP45585.1 - 1.9e-05 24.6 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDP45585.1 - 4.7e-05 22.8 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EDP45585.1 - 0.00068 18.7 0.2 0.0052 15.9 0.1 2.1 1 1 0 1 1 1 1 ATPase MipZ Cache_3 PF14827.1 EDP45585.1 - 0.012 15.5 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase AAA_26 PF13500.1 EDP45585.1 - 0.012 15.2 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EDP45585.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EDP45585.1 - 0.048 13.4 0.4 1.8 8.3 0.0 2.5 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EDP45585.1 - 0.06 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2017 PF09438.5 EDP45585.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) AAA_17 PF13207.1 EDP45585.1 - 0.13 13.1 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 EDP45586.1 - 2.2e-23 81.6 25.3 3e-06 26.8 2.6 7.5 6 3 3 9 9 9 6 TPR repeat TPR_2 PF07719.12 EDP45586.1 - 7.7e-18 62.9 36.3 0.00014 21.4 0.1 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDP45586.1 - 3.8e-15 54.7 20.5 0.0022 17.5 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDP45586.1 - 1.7e-12 46.8 44.5 0.00012 22.4 0.9 10.5 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDP45586.1 - 6.4e-08 32.4 34.0 0.00028 20.7 1.1 7.5 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EDP45586.1 - 7.6e-08 32.8 55.6 0.00079 20.0 1.8 9.6 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDP45586.1 - 1.1e-07 31.0 1.4 1.8 8.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EDP45586.1 - 1.8e-07 31.2 17.9 0.027 14.5 0.1 6.1 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDP45586.1 - 1.5e-06 27.9 9.8 7.5 7.0 0.0 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDP45586.1 - 2.7e-06 26.7 24.6 0.02 14.6 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDP45586.1 - 9.7e-05 22.6 27.7 3 8.2 0.4 8.4 7 2 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDP45586.1 - 0.15 12.5 0.0 0.15 12.5 0.0 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Fer4 PF00037.22 EDP45587.1 - 7e-14 50.7 17.0 1.2e-08 34.2 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EDP45587.1 - 6.3e-12 45.6 9.8 1e-11 45.0 6.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EDP45587.1 - 3.4e-11 43.7 17.2 6.9e-08 33.1 6.4 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EDP45587.1 - 7.4e-10 38.4 11.4 2.2e-09 36.9 8.1 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EDP45587.1 - 8.3e-10 38.3 4.3 0.00029 20.6 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDP45587.1 - 1.5e-09 37.7 20.8 7.4e-07 29.1 7.8 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDP45587.1 - 1.9e-09 37.6 10.0 3.5e-09 36.8 7.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDP45587.1 - 6.1e-08 32.1 15.0 0.00027 20.6 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EDP45587.1 - 6.8e-07 29.1 9.6 0.00029 20.9 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EDP45587.1 - 8.2e-07 28.6 17.7 0.00075 19.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EDP45587.1 - 1.2e-05 25.5 10.6 0.00028 21.1 8.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDP45587.1 - 1.4e-05 25.4 9.8 0.015 15.7 0.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EDP45587.1 - 3e-05 24.4 7.4 0.021 15.3 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EDP45587.1 - 0.00066 20.0 15.0 0.12 12.7 2.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EDP45587.1 - 0.01 16.3 18.4 0.015 15.8 4.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EDP45587.1 - 0.54 10.4 4.7 8.6 6.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain GKAP PF03359.8 EDP45588.1 - 0.0094 15.6 3.8 0.011 15.4 2.7 1.2 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein RNase_H2-Ydr279 PF09468.5 EDP45589.1 - 6.7e-19 68.2 0.0 1.1e-18 67.4 0.0 1.3 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF455 PF04305.9 EDP45590.1 - 2.5e-89 298.8 0.0 3e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Filaggrin PF03516.8 EDP45591.1 - 1.1 9.7 0.1 1.1 9.7 0.1 3.3 3 0 0 3 3 3 0 Filaggrin 2Fe-2S_thioredx PF01257.14 EDP45592.1 - 1.3e-55 187.0 0.6 2.3e-55 186.1 0.2 1.5 2 0 0 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin Adeno_E3B PF03376.9 EDP45592.1 - 0.85 9.5 5.5 0.95 9.4 0.1 3.1 3 0 0 3 3 3 0 Adenovirus E3B protein adh_short PF00106.20 EDP45593.1 - 2.3e-10 40.6 1.1 3.5e-07 30.2 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDP45593.1 - 1.7e-05 24.6 0.4 0.00062 19.4 0.1 2.3 2 1 0 2 2 2 1 KR domain RNA_polI_A34 PF08208.6 EDP45594.1 - 5.7e-15 55.5 4.2 1.4e-07 31.3 5.2 2.1 1 1 1 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Tom37 PF10568.4 EDP45595.1 - 0.0026 17.9 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF1510 PF07423.6 EDP45595.1 - 0.0087 15.4 9.8 0.012 14.9 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) GST_C_2 PF13410.1 EDP45595.1 - 0.0091 15.8 0.1 0.025 14.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EDP45595.1 - 0.083 12.7 1.3 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF4357 PF14267.1 EDP45596.1 - 0.13 11.8 0.1 0.39 10.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) tRNA-synt_1g PF09334.6 EDP45597.1 - 1.2e-108 363.2 0.0 2.5e-108 362.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDP45597.1 - 1.2e-16 59.9 1.7 5e-09 34.7 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDP45597.1 - 1.5e-08 34.1 0.0 0.0038 16.3 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EDP45597.1 - 0.02 13.5 0.0 0.04 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) HLH PF00010.21 EDP45598.1 - 7.2e-07 28.8 0.3 2.2e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain ApbA PF02558.11 EDP45599.1 - 3.4e-27 94.7 0.0 4.6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDP45599.1 - 3.9e-23 81.7 0.0 1e-22 80.4 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal HI0933_like PF03486.9 EDP45599.1 - 0.11 10.9 0.0 10 4.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein tRNA-synt_2 PF00152.15 EDP45600.1 - 7.4e-74 248.5 0.1 1.7e-73 247.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EDP45600.1 - 1.9e-12 46.6 0.0 2.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EDP45600.1 - 0.00013 21.3 1.9 0.037 13.2 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EDP45600.1 - 0.0068 16.2 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Prog_receptor PF02161.10 EDP45601.1 - 0.036 12.9 11.4 0.079 11.7 7.9 1.5 1 0 0 1 1 1 0 Progesterone receptor Folate_carrier PF01770.13 EDP45601.1 - 0.65 8.4 3.6 1.2 7.6 2.5 1.4 1 0 0 1 1 1 0 Reduced folate carrier SID-1_RNA_chan PF13965.1 EDP45601.1 - 5.8 4.9 5.6 10 4.1 3.9 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BNR_3 PF13859.1 EDP45601.1 - 7.3 5.5 9.0 0.38 9.7 2.2 1.7 2 0 0 2 2 2 0 BNR repeat-like domain HA2 PF04408.18 EDP45602.1 - 1.3e-18 66.8 0.4 2.5e-18 65.9 0.3 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDP45602.1 - 1.3e-17 63.6 0.1 3.1e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDP45602.1 - 2.1e-12 46.7 0.0 4.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SCA7 PF08313.7 EDP45603.1 - 3.3e-28 97.0 1.8 3.6e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-TRAF PF02176.13 EDP45603.1 - 0.02 15.2 0.9 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger DUF1776 PF08643.5 EDP45604.1 - 0.0013 17.9 0.1 0.0078 15.3 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) SKI PF01202.17 EDP45604.1 - 0.11 12.4 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase DASH_Dad2 PF08654.5 EDP45605.1 - 4.8e-23 81.1 0.2 6.1e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Synaptonemal_3 PF15191.1 EDP45605.1 - 0.092 12.4 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 DivIC PF04977.10 EDP45605.1 - 0.81 9.2 4.9 0.28 10.6 1.6 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF2034 PF10356.4 EDP45606.1 - 1.8e-19 69.6 3.5 3e-18 65.6 2.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EDP45606.1 - 3.8e-07 29.8 0.0 1.1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Restriction endonuclease DUF1018 PF06252.7 EDP45606.1 - 0.086 13.3 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Ribosomal_S30 PF04758.9 EDP45607.1 - 2.2e-30 104.1 6.3 2.4e-30 104.0 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 HIRA_B PF09453.5 EDP45607.1 - 0.28 10.7 0.3 0.28 10.7 0.2 2.0 2 0 0 2 2 2 0 HIRA B motif S10_plectin PF03501.10 EDP45608.1 - 2e-40 136.5 0.1 2.4e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain zf-Tim10_DDP PF02953.10 EDP45609.1 - 1.2e-13 50.1 0.1 1.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Asp PF00026.18 EDP45610.1 - 4.4e-70 236.4 0.1 5.6e-70 236.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDP45610.1 - 3.5e-07 30.2 0.1 3.1e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDP45610.1 - 0.0001 21.9 0.0 0.00024 20.6 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DnaJ PF00226.26 EDP45611.1 - 1e-23 82.8 0.8 1.7e-23 82.1 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDP45611.1 - 1.4e-21 76.1 0.0 5.3e-18 64.6 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDP45611.1 - 4.4e-16 58.6 13.4 6.9e-16 58.0 9.3 1.3 1 0 0 1 1 1 1 DnaJ central domain A2L_zn_ribbon PF08792.5 EDP45611.1 - 0.011 15.2 6.4 0.46 10.0 0.0 3.9 5 0 0 5 5 5 0 A2L zinc ribbon domain Cytochrome_CBB3 PF13442.1 EDP45611.1 - 0.076 13.1 0.3 0.32 11.2 0.2 2.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Opy2 PF09463.5 EDP45611.1 - 0.2 11.7 12.1 2 8.5 2.5 2.4 2 0 0 2 2 2 0 Opy2 protein DZR PF12773.2 EDP45611.1 - 0.27 11.1 11.0 3.1 7.7 8.2 2.2 1 1 2 3 3 3 0 Double zinc ribbon Cytochrom_c3_2 PF14537.1 EDP45611.1 - 6.4 7.1 11.2 0.53 10.6 4.1 2.0 2 0 0 2 2 2 0 Cytochrome c3 FA_hydroxylase PF04116.8 EDP45612.1 - 4.2e-15 56.1 15.7 4.2e-15 56.1 10.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GHL1-3 PF11308.3 EDP45612.1 - 0.0016 17.8 0.8 0.0028 17.0 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Response_reg PF00072.19 EDP45613.1 - 2.5e-22 78.9 0.1 9.7e-16 57.7 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain NCA2 PF08637.5 EDP45614.1 - 1e-56 191.9 0.0 1.4e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 NMT PF01233.14 EDP45615.1 - 7.6e-73 243.4 0.0 1.5e-72 242.5 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EDP45615.1 - 2.6e-65 219.3 0.0 4.9e-65 218.4 0.0 1.5 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EDP45615.1 - 7.8e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EDP45616.1 - 0.0051 16.4 2.1 0.0051 16.4 1.5 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Limkain-b1 PF11608.3 EDP45616.1 - 0.025 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 RRM_1 PF00076.17 EDP45616.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_ribbon_recom PF13408.1 EDP45616.1 - 5.6 7.2 9.0 0.2 11.9 1.9 1.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-CCCH_2 PF14608.1 EDP45616.1 - 8.2 6.5 7.5 1.9 8.5 1.4 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Complex1_LYR_1 PF13232.1 EDP45617.1 - 0.0055 16.8 1.0 0.0092 16.1 0.1 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDP45617.1 - 0.09 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Ribosomal_L31 PF01197.13 EDP45617.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 HECT PF00632.20 EDP45618.1 - 5.6e-93 311.5 0.0 7.8e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EDP45618.1 - 5.4e-33 112.4 18.3 8e-11 41.5 0.2 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EDP45618.1 - 4.5e-12 45.6 0.5 1.1e-11 44.4 0.3 1.6 1 0 0 1 1 1 1 C2 domain Nuc_sug_transp PF04142.10 EDP45619.1 - 9.9e-09 34.6 2.7 1.5e-08 34.0 1.8 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EDP45619.1 - 0.0027 16.6 5.5 0.004 16.1 3.8 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EDP45619.1 - 0.0082 16.3 6.2 0.0082 16.3 4.3 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EDP45619.1 - 0.011 15.4 12.6 0.22 11.1 2.0 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family EamA PF00892.15 EDP45619.1 - 0.011 15.7 18.2 0.036 14.1 5.2 3.2 2 1 1 3 3 3 0 EamA-like transporter family WCOR413 PF05562.6 EDP45619.1 - 0.044 13.3 3.7 0.077 12.5 2.6 1.4 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 Hist_deacetyl PF00850.14 EDP45620.1 - 2.7e-74 250.2 0.0 3.1e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Polysacc_deac_1 PF01522.16 EDP45621.1 - 2e-28 98.4 0.0 4.6e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EDP45622.1 - 2.9e-27 94.7 0.0 6.6e-27 93.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Serglycin PF04360.7 EDP45622.1 - 0.052 13.2 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Serglycin HEAT_2 PF13646.1 EDP45623.1 - 3.1e-29 101.1 70.9 1.2e-07 31.8 0.3 15.7 9 6 8 17 17 17 11 HEAT repeats HEAT PF02985.17 EDP45623.1 - 4.6e-27 91.6 36.8 0.0086 16.0 0.1 22.4 25 0 0 25 25 24 6 HEAT repeat HEAT_EZ PF13513.1 EDP45623.1 - 5.1e-24 84.0 80.2 5.6e-05 23.4 0.1 22.1 16 6 8 24 24 24 10 HEAT-like repeat DUF3554 PF12074.3 EDP45623.1 - 3.5e-16 59.5 0.2 1.2e-14 54.5 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3554) Vac14_Fab1_bd PF12755.2 EDP45623.1 - 3.7e-08 33.6 0.0 2.4 8.6 0.0 7.0 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDP45623.1 - 1e-05 25.0 4.1 0.89 8.8 0.0 7.1 8 1 1 9 9 9 2 CLASP N terminal Ipi1_N PF12333.3 EDP45623.1 - 0.0023 17.8 1.4 11 6.0 0.0 6.1 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EDP45623.1 - 0.0034 17.1 8.4 2.7 7.9 0.0 7.5 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat HrpF PF06266.7 EDP45623.1 - 0.0051 16.9 0.1 0.024 14.7 0.1 2.2 1 0 0 1 1 1 1 HrpF protein DUF2669 PF10876.3 EDP45623.1 - 0.011 15.4 0.7 24 4.6 0.0 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2669) Adaptin_N PF01602.15 EDP45623.1 - 0.053 11.8 10.1 15 3.7 0.0 6.5 5 3 2 8 8 8 0 Adaptin N terminal region G-alpha PF00503.15 EDP45624.1 - 1.5e-122 409.0 0.1 1.8e-122 408.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EDP45624.1 - 1.4e-15 56.9 1.4 4e-10 39.1 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDP45624.1 - 6.9e-05 22.0 0.3 0.25 10.4 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EDP45624.1 - 0.0037 17.7 0.1 0.55 10.7 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EDP45624.1 - 0.015 14.7 0.0 1.6 8.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EDP45624.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDP45624.1 - 0.092 12.7 0.1 1.1 9.2 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase FMN_dh PF01070.13 EDP45625.1 - 1.1e-114 383.0 0.0 1.4e-114 382.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDP45625.1 - 1.8e-21 75.6 0.0 3.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDP45625.1 - 7.6e-05 21.7 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDP45625.1 - 0.00092 18.1 0.3 0.002 17.0 0.1 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain VASP_tetra PF08776.6 EDP45625.1 - 0.024 13.9 0.3 0.05 12.9 0.2 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain NMO PF03060.10 EDP45625.1 - 0.04 13.0 0.1 0.063 12.4 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 EDP45625.1 - 0.046 12.7 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Uso1_p115_head PF04869.9 EDP45626.1 - 1.9e-52 178.0 0.0 1e-50 172.2 0.0 3.1 2 2 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region WXG100 PF06013.7 EDP45626.1 - 0.0042 17.0 3.5 0.0042 17.0 2.4 3.2 3 0 0 3 3 3 1 Proteins of 100 residues with WXG MMS19_N PF14500.1 EDP45626.1 - 0.02 14.1 0.5 0.21 10.8 0.1 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HALZ PF02183.13 EDP45626.1 - 3.8 7.2 13.1 0.065 12.9 0.3 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper ADIP PF11559.3 EDP45626.1 - 6.3 6.6 27.8 3.2 7.6 5.8 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding PEARLI-4 PF05278.7 EDP45626.1 - 7.6 5.8 15.1 0.12 11.7 0.9 3.0 1 1 2 3 3 3 0 Arabidopsis phospholipase-like protein (PEARLI 4) WD40 PF00400.27 EDP45628.1 - 2.8e-13 49.1 13.0 2.3e-05 24.0 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 EDP45629.1 - 2e-05 24.4 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain Reo_sigmaC PF04582.7 EDP45630.1 - 0.005 16.0 17.5 0.0062 15.7 2.7 3.6 2 2 1 3 3 3 3 Reovirus sigma C capsid protein GAS PF13851.1 EDP45630.1 - 2.8 7.1 49.2 1.9 7.6 8.7 3.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Y_phosphatase PF00102.22 EDP45631.1 - 9.2e-54 182.2 0.0 2.8e-53 180.6 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EDP45631.1 - 1.4e-06 28.6 0.0 1.8e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EDP45631.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EDP45631.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EDP45631.1 - 0.092 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Lectin_leg-like PF03388.8 EDP45632.1 - 3e-56 190.1 0.2 4.2e-56 189.6 0.2 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EDP45632.1 - 4.6e-05 22.8 0.1 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain CTP_transf_1 PF01148.15 EDP45632.1 - 0.24 11.0 3.9 0.45 10.1 2.7 1.4 1 0 0 1 1 1 0 Cytidylyltransferase family RNase_T PF00929.19 EDP45633.1 - 6.7e-22 78.5 0.0 8.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Peptidase_C2 PF00648.16 EDP45634.1 - 2e-17 63.1 0.0 3.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EDP45634.1 - 1.4e-05 24.9 0.3 2.3e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pantoate_transf PF02548.10 EDP45635.1 - 2.7e-81 272.5 0.7 2.7e-76 256.1 0.1 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EDP45635.1 - 2.2e-05 23.8 0.1 8.1e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ABC_tran PF00005.22 EDP45636.1 - 6.4e-22 78.3 0.0 7.4e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDP45636.1 - 8.7e-07 29.1 0.0 0.0023 17.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EDP45636.1 - 0.0007 19.4 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDP45636.1 - 0.00082 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDP45636.1 - 0.0011 18.8 0.3 0.29 11.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDP45636.1 - 0.0019 18.1 0.9 0.0088 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EDP45636.1 - 0.0046 16.5 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EDP45636.1 - 0.015 15.7 0.0 0.053 14.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 EDP45636.1 - 0.018 14.4 0.1 0.24 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EDP45636.1 - 0.025 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EDP45636.1 - 0.029 14.0 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 EDP45636.1 - 0.029 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EDP45636.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EDP45636.1 - 0.05 13.9 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDP45636.1 - 0.13 12.4 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDP45636.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EDP45636.1 - 0.31 10.0 0.0 0.53 9.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Glyco_hydro_31 PF01055.21 EDP45637.1 - 5e-59 200.2 0.0 5.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_31 PF01055.21 EDP45638.1 - 6.6e-33 114.1 0.2 7.8e-33 113.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDP45639.1 - 2.2e-18 65.8 0.0 3.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Galactose mutarotase-like eIF2A PF08662.6 EDP45640.1 - 3.4e-79 265.0 0.0 1.2e-76 256.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EDP45640.1 - 0.076 10.8 0.0 2.5 5.8 0.0 2.4 3 0 0 3 3 3 0 IKI3 family WD40 PF00400.27 EDP45640.1 - 0.17 11.8 0.5 4.8 7.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat CDV3 PF15359.1 EDP45640.1 - 1.3 9.1 10.9 0.24 11.5 3.3 2.6 2 1 1 3 3 3 0 Carnitine deficiency-associated protein 3 PrmA PF06325.8 EDP45641.1 - 1.4e-10 40.8 0.0 2.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EDP45641.1 - 1.7e-09 37.4 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDP45641.1 - 1.2e-07 32.2 0.0 2.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDP45641.1 - 1.4e-07 31.5 0.1 3.8e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EDP45641.1 - 8.5e-07 28.2 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 EDP45641.1 - 6e-06 25.7 0.1 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDP45641.1 - 9.7e-06 25.8 0.1 5.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDP45641.1 - 4.4e-05 23.8 0.1 0.00028 21.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDP45641.1 - 8.2e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDP45641.1 - 0.0002 20.5 0.0 0.00082 18.5 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EDP45641.1 - 0.001 19.9 0.0 0.0024 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDP45641.1 - 0.002 18.5 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDP45641.1 - 0.0056 15.4 0.0 0.0095 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 EDP45641.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EDP45641.1 - 0.047 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EDP45641.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.9 EDP45641.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Chromo PF00385.19 EDP45642.1 - 2e-07 30.5 0.3 3.7e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EDP45642.1 - 3.4e-06 26.8 0.0 2.5e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 Chromo shadow domain Prok-TraM PF09228.5 EDP45642.1 - 1.1 9.5 3.4 4.8 7.3 0.1 2.7 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Peptidase_M28 PF04389.12 EDP45643.1 - 1.9e-28 99.3 0.0 3.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDP45643.1 - 0.00022 20.7 0.0 0.00063 19.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RasGEF_N_2 PF14663.1 EDP45643.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GIDA PF01134.17 EDP45644.1 - 5.2e-53 180.3 0.0 7.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EDP45644.1 - 3.2e-16 59.1 0.0 1.2e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 GidA associated domain 3 PH PF00169.24 EDP45646.1 - 6e-07 29.6 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 PH domain Anillin PF08174.6 EDP45646.1 - 0.00085 19.3 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin