# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- APH PF01636.18 KXX72774.1 - 1.5e-05 24.8 0.1 2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KXX72774.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.15 KXX72774.1 - 0.021 14.3 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KXX72774.1 - 0.077 12.0 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NACHT PF05729.7 KXX72775.1 - 1.2e-10 41.3 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX72775.1 - 2e-08 34.4 0.3 4.3e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KXX72775.1 - 7.8e-06 24.9 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KXX72775.1 - 0.0082 15.1 0.2 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain HTH_30 PF13556.1 KXX72775.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain APS_kinase PF01583.15 KXX72775.1 - 0.046 13.3 0.1 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KXX72775.1 - 0.058 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX72775.1 - 0.099 13.4 0.3 0.49 11.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX72775.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 KXX72775.1 - 0.19 11.1 0.1 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 KXX72775.1 - 0.21 11.7 0.2 0.64 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase DUF676 PF05057.9 KXX72776.1 - 0.0036 16.6 0.0 0.0093 15.2 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KXX72776.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 KXX72778.1 - 2.8e-24 85.4 0.0 4.2e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX72778.1 - 5.2e-22 78.0 0.0 6.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX72778.1 - 1.6e-15 56.8 0.0 2.2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KXX72778.1 - 8.1e-15 55.1 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX72778.1 - 1.7e-13 51.1 0.0 2.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX72778.1 - 1.7e-12 47.5 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX72778.1 - 1.3e-10 41.2 0.0 1.6e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX72778.1 - 9.9e-10 38.0 0.0 1.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX72778.1 - 2.4e-08 34.0 2.0 5.4e-08 32.8 1.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX72778.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 KXX72778.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KXX72778.1 - 0.0031 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KXX72778.1 - 0.0046 16.0 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KXX72778.1 - 0.006 16.0 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KXX72778.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KXX72778.1 - 0.015 14.8 0.1 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.7 KXX72778.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.11 KXX72778.1 - 0.031 12.6 0.0 0.1 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 KXX72778.1 - 0.038 13.2 0.0 2.2 7.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain LRV PF01816.12 KXX72778.1 - 0.98 9.7 4.8 11 6.4 0.2 2.9 2 0 0 2 2 2 0 Leucine rich repeat variant AMP-binding PF00501.23 KXX72779.1 - 6.8e-79 265.1 0.0 8.5e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX72779.1 - 3.8e-17 63.0 1.9 1.1e-16 61.5 0.1 2.7 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 KXX72780.1 - 2.4e-21 76.0 0.0 3.7e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX72780.1 - 3.9e-06 26.1 0.0 8.6e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KXX72780.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family ENTH PF01417.15 KXX72781.1 - 1.3e-50 170.3 0.1 2.5e-50 169.5 0.1 1.5 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 KXX72781.1 - 0.045 13.3 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.1 KXX72781.1 - 0.091 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 KXX72781.1 - 0.14 11.7 8.7 0.039 13.5 1.1 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif PAT1 PF09770.4 KXX72781.1 - 2.3 6.3 62.3 5 5.2 43.2 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 KXX72781.1 - 9.6 5.5 19.0 1.2 8.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) NUDIX PF00293.23 KXX72782.1 - 1.2e-18 67.0 0.1 2.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KXX72782.1 - 2.5e-17 63.0 0.2 1.3e-16 60.6 0.1 2.2 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KXX72782.1 - 1.2e-08 34.2 1.0 2.2e-08 33.4 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF58 PF01882.13 KXX72782.1 - 0.021 14.9 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF58 Ribosomal_L1 PF00687.16 KXX72783.1 - 8.1e-54 182.2 0.6 9.6e-54 182.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Fungal_trans PF04082.13 KXX72785.1 - 0.12 11.2 1.0 0.2 10.5 0.7 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KXX72786.1 - 0.0044 17.2 3.6 0.0047 17.1 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 KXX72786.1 - 0.1 12.1 0.3 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KXX72786.1 - 0.11 12.2 0.3 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Mut7-C PF01927.11 KXX72786.1 - 0.14 12.0 1.1 0.27 11.2 0.8 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain TRP PF06011.7 KXX72787.1 - 1.3e-132 442.5 15.6 1.7e-132 442.1 10.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX72787.1 - 3.4e-39 134.0 2.3 5.2e-39 133.5 1.6 1.3 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.1 KXX72787.1 - 3.7 7.7 5.7 15 5.7 0.1 2.7 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Ribonucleas_3_3 PF14622.1 KXX72788.1 - 5.2e-10 39.3 0.0 7.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KXX72788.1 - 1.1e-05 25.8 0.0 2.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Reductase_C PF14759.1 KXX72788.1 - 0.0058 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Reductase C-terminal Methyltransf_18 PF12847.2 KXX72789.1 - 7.8e-12 45.7 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX72789.1 - 4.4e-09 36.6 0.0 9.6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX72789.1 - 1.4e-08 35.1 0.0 1.1e-07 32.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX72789.1 - 6.2e-07 29.4 0.1 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX72789.1 - 8.7e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX72789.1 - 2.3e-06 28.0 0.0 2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX72789.1 - 3.6e-06 26.2 0.0 1.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KXX72789.1 - 0.0037 16.8 0.0 0.055 13.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX72789.1 - 0.021 14.2 0.0 0.95 8.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_9 PF08003.6 KXX72789.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Radial_spoke PF04712.7 KXX72790.1 - 0.077 11.7 8.5 0.098 11.3 5.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein VID27 PF08553.5 KXX72790.1 - 0.085 11.0 5.8 0.1 10.8 4.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 KXX72790.1 - 0.13 10.2 5.3 0.15 10.1 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KXX72790.1 - 0.17 10.3 10.8 0.17 10.3 7.5 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 KXX72790.1 - 0.2 11.3 3.8 0.29 10.8 2.6 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 KXX72790.1 - 0.24 10.6 4.4 0.4 9.8 3.1 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KXX72790.1 - 0.26 10.2 6.9 0.32 9.9 4.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.12 KXX72790.1 - 0.41 10.4 2.3 0.6 9.8 1.6 1.2 1 0 0 1 1 1 0 DDHD domain RNA_pol_3_Rpc31 PF11705.3 KXX72790.1 - 0.49 10.3 14.6 0.77 9.6 10.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 KXX72790.1 - 0.6 7.9 11.3 0.61 7.9 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family Pilt PF15453.1 KXX72790.1 - 0.66 9.6 5.7 1 8.9 3.9 1.3 1 1 0 1 1 1 0 Protein incorporated later into Tight Junctions Nucleoplasmin PF03066.10 KXX72790.1 - 0.72 9.3 14.0 1.1 8.7 9.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 KXX72790.1 - 0.85 7.4 4.5 0.92 7.2 3.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 KXX72790.1 - 1.2 7.8 13.8 1.4 7.5 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 KXX72790.1 - 1.3 7.7 10.2 1.6 7.4 7.1 1.1 1 0 0 1 1 1 0 Paf1 DUF4337 PF14235.1 KXX72790.1 - 1.5 8.6 4.4 2.4 7.9 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Prothymosin PF03247.9 KXX72790.1 - 2.5 8.2 25.0 4.4 7.5 17.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF740 PF05340.7 KXX72790.1 - 4.1 5.6 6.3 5 5.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) EMP24_GP25L PF01105.19 KXX72791.1 - 3.3e-46 157.2 5.0 3.8e-46 157.1 3.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4460 PF14687.1 KXX72791.1 - 0.052 13.3 0.4 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) PhoD PF09423.5 KXX72792.1 - 3.1e-67 227.1 0.0 4.2e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase RPE65 PF03055.10 KXX72794.1 - 5.2e-128 427.6 0.0 5.9e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fork_head PF00250.13 KXX72795.1 - 7.2e-34 115.6 0.1 1.4e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Fork head domain TPR_10 PF13374.1 KXX72796.1 - 6.8e-27 92.5 1.2 2.7e-14 52.5 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KXX72796.1 - 2.1e-26 91.6 0.8 4.9e-13 48.8 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX72796.1 - 1.1e-09 37.3 0.1 5.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX72796.1 - 4.2e-09 35.9 0.0 5.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KXX72796.1 - 1.1e-07 31.1 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX72796.1 - 3.2e-07 30.0 0.1 0.005 16.9 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX72796.1 - 1.4e-06 27.7 0.1 0.00062 19.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 KXX72796.1 - 2.3e-05 24.0 0.1 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX72796.1 - 2.8e-05 24.6 0.0 4.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX72796.1 - 0.00012 22.3 0.0 0.023 15.0 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX72796.1 - 0.00046 20.2 0.1 0.0041 17.2 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KXX72796.1 - 0.00085 18.9 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 KXX72796.1 - 0.0011 19.1 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.15 KXX72796.1 - 0.0085 16.0 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 1 PPR repeat TPR_15 PF13429.1 KXX72796.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Rab5-bind PF09311.6 KXX72796.1 - 0.016 15.1 0.0 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Rabaptin-like protein TPR_20 PF14561.1 KXX72796.1 - 0.021 14.8 0.0 0.91 9.6 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX72796.1 - 0.024 15.2 0.0 0.52 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FTCD PF02971.9 KXX72796.1 - 0.068 12.7 0.0 1.4 8.5 0.0 2.0 1 1 1 2 2 2 0 Formiminotransferase domain Acyl_transf_1 PF00698.16 KXX72797.1 - 4.6e-62 210.1 0.0 6.7e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX72797.1 - 1.6e-60 204.8 1.5 2.6e-60 204.1 1.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KXX72797.1 - 2.5e-30 104.7 0.0 5.5e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX72797.1 - 1.9e-19 69.9 0.0 4.9e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 KXX72797.1 - 1.1e-18 67.6 0.4 1.1e-18 67.6 0.3 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_11 PF08241.7 KXX72797.1 - 7.7e-13 48.7 0.0 2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX72797.1 - 1.2e-11 45.1 0.0 3.6e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX72797.1 - 2.5e-11 43.5 0.0 8.8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX72797.1 - 2.6e-11 43.3 0.0 5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX72797.1 - 2e-07 31.2 0.0 4.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX72797.1 - 6.2e-05 23.0 0.2 0.00031 20.7 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 KXX72797.1 - 0.00097 18.5 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KXX72797.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 KXX72797.1 - 0.0043 16.6 0.0 0.0096 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KXX72797.1 - 0.0081 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 KXX72797.1 - 0.0099 15.5 0.7 0.027 14.1 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RrnaAD PF00398.15 KXX72797.1 - 0.57 9.1 0.0 1 8.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HET PF06985.6 KXX72798.1 - 0.00036 20.7 0.0 0.00037 20.6 0.0 1.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 KXX72799.1 - 6.2e-29 100.8 0.1 9.4e-29 100.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX72799.1 - 4e-15 56.2 0.3 6.3e-15 55.6 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX72799.1 - 0.00033 20.1 0.0 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX72799.1 - 0.0017 17.1 0.0 0.0074 15.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KXX72799.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 KXX72799.1 - 0.04 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 KXX72799.1 - 0.048 13.4 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase KIP1 PF07765.7 KXX72799.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 KIP1-like protein HMGL-like PF00682.14 KXX72800.1 - 1.2e-66 224.7 0.0 2.1e-66 224.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KXX72800.1 - 4e-24 84.9 0.0 1.5e-23 83.0 0.0 2.1 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain DUF2046 PF09755.4 KXX72802.1 - 0.0061 15.4 1.9 0.013 14.4 1.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) IncA PF04156.9 KXX72802.1 - 0.0062 16.1 2.5 0.88 9.1 0.2 2.1 2 0 0 2 2 2 2 IncA protein CENP-F_N PF10481.4 KXX72802.1 - 0.015 14.7 0.7 1.4 8.1 0.2 2.3 2 0 0 2 2 2 0 Cenp-F N-terminal domain TMCO5 PF14992.1 KXX72802.1 - 0.12 11.4 2.5 0.66 9.0 0.0 2.0 2 0 0 2 2 2 0 TMCO5 family DivIC PF04977.10 KXX72802.1 - 0.27 10.7 3.8 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.7 KXX72802.1 - 0.44 10.4 4.6 12 5.9 0.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SlyX PF04102.7 KXX72802.1 - 0.99 9.8 6.0 2.6 8.5 1.3 2.4 2 0 0 2 2 2 0 SlyX DUF904 PF06005.7 KXX72802.1 - 1.2 9.5 7.6 5.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF1192 PF06698.6 KXX72802.1 - 1.3 8.9 3.8 0.57 10.0 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 KXX72802.1 - 1.6 9.1 4.4 7.8 6.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DAO PF01266.19 KXX72803.1 - 2.8e-54 184.4 2.4 3.2e-54 184.2 1.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX72803.1 - 3.1e-06 27.1 1.4 7.1e-06 25.9 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX72803.1 - 0.00024 21.2 0.2 0.01 15.8 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX72803.1 - 0.0092 15.0 0.4 0.075 12.0 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX72803.1 - 0.028 14.8 0.2 0.094 13.1 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KXX72803.1 - 0.096 12.4 0.2 0.36 10.5 0.2 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 KXX72803.1 - 0.25 10.3 3.4 1.2 8.1 2.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX72803.1 - 1.8 7.3 5.8 3.9 6.1 4.0 1.6 1 1 0 1 1 1 0 FAD binding domain ELFV_dehydrog PF00208.16 KXX72804.1 - 5.3e-61 206.2 0.0 9.1e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KXX72804.1 - 3.4e-20 71.1 0.0 9.7e-15 53.1 0.0 2.7 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KXX72804.1 - 0.0008 18.9 0.1 0.0035 16.9 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FAD_binding_4 PF01565.18 KXX72805.1 - 1.1e-22 80.0 2.2 2.4e-22 78.8 1.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX72805.1 - 9.5e-14 51.0 0.1 2.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like AP_endonuc_2 PF01261.19 KXX72805.1 - 0.00057 19.2 0.0 1.4 8.1 0.0 2.6 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel p450 PF00067.17 KXX72806.1 - 1.5e-61 208.3 0.0 1.8e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 KXX72807.1 - 5.7e-09 35.7 11.4 0.016 15.5 0.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX72807.1 - 1.1e-06 28.5 13.8 0.0028 17.8 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger PIG-X PF08320.7 KXX72809.1 - 2.3e-66 223.0 0.0 9e-66 221.0 0.0 1.9 2 0 0 2 2 2 1 PIG-X / PBN1 Homeobox PF00046.24 KXX72810.1 - 3.2e-10 39.4 0.4 2.2e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 Homeobox domain Rhodanese PF00581.15 KXX72810.1 - 2.7e-08 34.1 0.0 7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C14 PF00656.17 KXX72810.1 - 0.02 14.6 0.1 0.082 12.5 0.1 2.1 1 1 0 1 1 1 0 Caspase domain DUF4611 PF15387.1 KXX72811.1 - 0.015 15.4 9.6 3.3 7.9 5.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 KXX72811.1 - 0.37 10.3 5.7 1.1 8.8 3.9 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KXX72811.1 - 1.1 8.7 13.2 3.4 7.1 9.1 1.7 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KXX72811.1 - 1.9 6.3 7.1 3.2 5.5 4.9 1.3 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 KXX72811.1 - 5.5 6.7 6.8 14 5.4 4.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 KXX72811.1 - 5.8 6.5 11.2 1.8 8.2 5.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.1 KXX72812.1 - 0.016 15.3 9.6 3 8.0 5.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 KXX72812.1 - 0.36 10.3 6.1 0.92 9.0 4.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 KXX72812.1 - 0.88 9.2 7.6 1.7 8.3 5.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 KXX72812.1 - 1 8.8 13.2 3.2 7.2 9.1 1.8 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KXX72812.1 - 2.3 6.0 7.0 3.5 5.4 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 KXX72812.1 - 4.3 7.1 6.7 11 5.7 4.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KXX72812.1 - 8.7 5.4 7.3 16 4.6 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein MDMPI_N PF11716.3 KXX72813.1 - 0.29 11.5 3.1 0.25 11.7 0.8 1.8 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Ribosomal_S15 PF00312.17 KXX72815.1 - 6.8e-14 51.3 0.7 1.4e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.11 KXX72816.1 - 2e-119 398.6 0.0 2.2e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DHHA1 PF02272.14 KXX72816.1 - 0.15 11.7 4.6 0.11 12.1 1.5 2.0 2 0 0 2 2 2 0 DHHA1 domain Ribosomal_S2 PF00318.15 KXX72817.1 - 5e-38 130.4 0.0 9.3e-23 80.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 2OG-FeII_Oxy_2 PF13532.1 KXX72819.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.6 KXX72820.1 - 2.5e-29 101.6 0.0 3.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein JAB PF01398.16 KXX72821.1 - 1.4e-12 47.3 0.0 2.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KXX72821.1 - 1.2e-06 27.9 0.1 3.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 KXX72821.1 - 0.00011 22.1 0.7 0.00048 20.0 0.0 2.3 3 0 0 3 3 3 1 USP8 dimerisation domain Caldesmon PF02029.10 KXX72821.1 - 0.0013 17.2 5.1 0.0019 16.7 3.5 1.1 1 0 0 1 1 1 1 Caldesmon NPL4 PF05021.10 KXX72821.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 NPL4 family DUF605 PF04652.11 KXX72821.1 - 1.3 8.3 6.5 1.8 7.9 4.5 1.2 1 0 0 1 1 1 0 Vta1 like Beta-lactamase PF00144.19 KXX72823.1 - 5.4e-35 120.9 0.0 1.1e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase Prefoldin_2 PF01920.15 KXX72824.1 - 1.1e-22 79.7 10.8 1.4e-22 79.4 7.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KXX72824.1 - 0.0016 18.0 9.0 0.0044 16.6 0.3 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 KXX72824.1 - 0.0048 16.6 3.1 0.0071 16.0 2.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1732 PF08340.6 KXX72824.1 - 0.007 16.1 1.1 0.091 12.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1732) DivIC PF04977.10 KXX72824.1 - 0.024 14.1 15.4 0.86 9.1 0.4 3.1 2 1 0 2 2 2 0 Septum formation initiator YgaB PF14182.1 KXX72824.1 - 0.051 13.8 0.9 0.051 13.8 0.7 2.4 2 1 0 2 2 2 0 YgaB-like protein Lzipper-MIP1 PF14389.1 KXX72824.1 - 0.064 13.3 5.1 0.62 10.2 1.2 2.2 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4201 PF13870.1 KXX72824.1 - 0.068 12.6 8.0 1.6 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) COG5 PF10392.4 KXX72824.1 - 0.069 13.1 1.0 5.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 KXX72824.1 - 0.074 12.6 14.0 0.22 11.0 9.7 1.7 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 KXX72824.1 - 0.077 11.9 11.0 0.16 10.8 7.7 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KXX72824.1 - 0.098 12.5 13.0 0.78 9.5 4.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.6 KXX72824.1 - 0.1 11.2 9.2 0.13 10.9 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.6 KXX72824.1 - 0.13 12.0 9.9 0.17 11.6 2.6 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF737 PF05300.6 KXX72824.1 - 0.17 11.8 8.9 0.8 9.6 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF737) COG2 PF06148.6 KXX72824.1 - 0.17 11.7 4.1 5.5 6.8 0.7 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sas10_Utp3 PF04000.10 KXX72824.1 - 0.18 12.0 5.1 0.91 9.7 1.2 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Nup54 PF13874.1 KXX72824.1 - 0.22 11.1 6.4 1.9 8.1 0.1 2.1 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Occludin_ELL PF07303.8 KXX72824.1 - 0.23 12.1 5.6 0.3 11.8 1.4 2.1 2 0 0 2 2 2 0 Occludin homology domain Laminin_II PF06009.7 KXX72824.1 - 0.32 10.7 5.2 4.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II Mnd1 PF03962.10 KXX72824.1 - 0.35 10.4 11.1 1.8 8.2 0.6 2.0 1 1 1 2 2 2 0 Mnd1 family NPV_P10 PF05531.7 KXX72824.1 - 0.47 10.7 4.1 1.6 9.0 1.7 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 KXX72824.1 - 0.56 9.3 11.8 2.5 7.2 8.2 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cortex-I_coil PF09304.5 KXX72824.1 - 0.59 10.2 10.7 2.5 8.1 2.9 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil HalX PF08663.5 KXX72824.1 - 0.63 10.0 3.0 21 5.1 0.8 2.9 2 1 1 3 3 3 0 HalX domain Tho2 PF11262.3 KXX72824.1 - 0.89 8.5 4.0 7 5.6 0.2 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 MutS_IV PF05190.13 KXX72824.1 - 0.9 9.7 4.0 4.1 7.6 0.6 2.2 2 0 0 2 2 2 0 MutS family domain IV DivIVA PF05103.8 KXX72824.1 - 0.95 9.5 9.4 1 9.4 0.5 2.3 2 0 0 2 2 2 0 DivIVA protein Cut12 PF11500.3 KXX72824.1 - 1.2 8.8 5.8 1.7 8.2 0.3 2.2 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Tektin PF03148.9 KXX72824.1 - 1.2 7.6 9.6 2.5 6.5 1.9 2.0 2 0 0 2 2 2 0 Tektin family FliJ PF02050.11 KXX72824.1 - 1.5 8.8 13.2 3.5 7.6 0.5 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4164 PF13747.1 KXX72824.1 - 1.8 8.7 6.1 17 5.6 1.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) ERp29 PF07749.7 KXX72824.1 - 1.9 9.1 5.6 12 6.5 3.9 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Fez1 PF06818.10 KXX72824.1 - 2.2 8.2 11.0 0.46 10.4 0.5 2.1 1 1 0 2 2 2 0 Fez1 DUF2408 PF10303.4 KXX72824.1 - 2.8 8.0 7.9 7.4 6.6 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Cep57_MT_bd PF06657.8 KXX72824.1 - 2.9 7.8 8.3 5.8 6.9 0.3 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CDC37_N PF03234.9 KXX72824.1 - 3.1 8.0 6.5 4.6 7.5 4.5 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF724 PF05266.9 KXX72824.1 - 3.3 7.3 9.9 5.1 6.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FemAB PF02388.11 KXX72824.1 - 3.3 6.2 11.2 6 5.4 3.4 2.0 1 1 1 2 2 2 0 FemAB family TPR_MLP1_2 PF07926.7 KXX72824.1 - 3.5 7.3 12.3 43 3.8 8.5 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 KXX72824.1 - 3.5 5.7 9.2 4.6 5.4 6.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Kinetocho_Slk19 PF12709.2 KXX72824.1 - 3.8 7.6 8.5 2.1 8.4 1.7 2.7 2 1 1 3 3 3 0 Central kinetochore-associated DUF4140 PF13600.1 KXX72824.1 - 4.1 7.9 6.6 14 6.2 1.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF964 PF06133.6 KXX72824.1 - 4.1 7.4 12.8 0.55 10.2 4.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF964) BRE1 PF08647.6 KXX72824.1 - 4.5 7.3 9.7 3.2 7.7 0.5 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Val_tRNA-synt_C PF10458.4 KXX72824.1 - 4.7 7.3 9.8 3 7.9 0.4 3.0 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF972 PF06156.8 KXX72824.1 - 5.9 7.2 8.7 1.4e+02 2.8 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 KXX72824.1 - 8.4 6.2 16.8 11 5.8 3.2 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HET PF06985.6 KXX72825.1 - 1.7e-29 102.7 0.0 3.6e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPN7 PF10602.4 KXX72827.1 - 0.016 14.6 0.1 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 BTB PF00651.26 KXX72829.1 - 0.00035 20.5 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HSP70 PF00012.15 KXX72831.1 - 0.0025 15.8 0.0 0.0025 15.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX72831.1 - 0.014 14.0 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Pectinesterase PF01095.14 KXX72831.1 - 0.023 13.2 0.1 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 Pectinesterase AIG1 PF04548.11 KXX72832.1 - 0.081 12.0 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family T2SF PF00482.18 KXX72832.1 - 0.14 12.0 0.7 0.32 10.9 0.5 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF221 PF02714.10 KXX72833.1 - 1.8e-101 339.2 25.3 1.8e-101 339.2 17.5 2.2 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KXX72833.1 - 5.2e-37 126.8 0.8 5.2e-37 126.8 0.5 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KXX72833.1 - 6.6e-15 54.7 0.0 1.7e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KXX72833.1 - 6.8e-08 32.9 1.4 0.013 16.0 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) FAD_binding_3 PF01494.14 KXX72834.1 - 9.3e-18 64.3 0.2 1.1e-16 60.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX72834.1 - 1.6e-06 28.0 0.5 3.7e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KXX72834.1 - 6.6e-05 21.8 0.0 0.00025 19.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KXX72834.1 - 0.00091 18.2 0.3 0.0014 17.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX72834.1 - 0.0044 17.3 0.4 0.022 15.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX72834.1 - 0.0047 16.8 1.4 0.011 15.5 0.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX72834.1 - 0.0083 15.0 0.4 0.022 13.6 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KXX72834.1 - 0.033 13.2 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 KXX72834.1 - 0.035 13.9 0.2 0.26 11.0 0.2 2.3 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 KXX72834.1 - 0.06 12.4 0.2 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KXX72834.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX72834.1 - 0.26 10.1 0.9 0.38 9.5 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 KXX72836.1 - 5.7e-34 117.3 45.4 5.7e-34 117.3 31.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KXX72836.1 - 3.9e-06 25.6 0.3 3.9e-06 25.6 0.2 1.8 2 0 0 2 2 2 1 LacY proton/sugar symporter Pex14_N PF04695.8 KXX72836.1 - 2.5 8.1 4.8 8.3 6.4 0.1 3.3 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HET PF06985.6 KXX72837.1 - 1.4e-19 70.6 1.4 2.6e-19 69.7 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HLH PF00010.21 KXX72838.1 - 4.8e-11 42.1 0.0 1.2e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 KXX72838.1 - 0.42 10.3 2.4 1 9.1 0.2 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper HLH PF00010.21 KXX72839.1 - 1.4e-12 47.0 0.0 1.4e-12 47.0 0.0 1.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF221 PF02714.10 KXX72840.1 - 2.9e-109 364.8 24.9 2.9e-109 364.8 17.2 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KXX72840.1 - 1.1e-44 151.7 1.1 1.1e-44 151.7 0.8 3.5 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KXX72840.1 - 5.6e-28 96.6 0.0 1.8e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KXX72840.1 - 1.7e-21 76.5 0.1 2.8e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Kelch_2 PF07646.10 KXX72841.1 - 0.0035 17.0 3.0 5.3 6.9 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 KXX72841.1 - 0.011 15.4 11.9 1.6 8.5 0.2 5.0 5 1 0 5 5 5 0 Galactose oxidase, central domain HALZ PF02183.13 KXX72842.1 - 0.63 9.8 4.1 4.5 7.0 0.5 2.8 1 1 2 3 3 3 0 Homeobox associated leucine zipper Mto2_bdg PF12808.2 KXX72842.1 - 1.3 9.1 9.1 0.36 10.9 0.5 3.1 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3505 PF12013.3 KXX72843.1 - 5.3e-09 36.2 0.0 9.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) CENP-B_dimeris PF09026.5 KXX72843.1 - 5.1 7.4 11.8 0.75 10.0 2.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DEAD PF00270.24 KXX72844.1 - 1.4e-05 24.6 0.0 0.021 14.3 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase PA14_2 PF10528.4 KXX72845.1 - 1.9e-09 37.4 0.2 8.6e-09 35.3 0.2 2.0 1 1 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KXX72845.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 PA14 domain zf-RING_2 PF13639.1 KXX72847.1 - 9.3e-13 47.7 2.7 9.3e-13 47.7 1.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KXX72847.1 - 3.4e-11 43.0 0.4 7e-11 42.0 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KXX72847.1 - 1.6e-06 27.8 0.5 3.3e-06 26.8 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KXX72847.1 - 3.6e-06 26.5 2.0 3.6e-06 26.5 1.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX72847.1 - 3.7e-06 26.8 2.2 3.7e-06 26.8 1.6 1.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX72847.1 - 8.4e-05 22.1 1.4 0.00016 21.2 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX72847.1 - 0.00015 21.3 2.4 0.00026 20.5 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX72847.1 - 0.0016 18.1 1.2 0.0053 16.4 0.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 KXX72847.1 - 0.017 15.0 3.4 0.44 10.5 2.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 KXX72847.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 KXX72847.1 - 0.028 14.2 0.2 0.059 13.1 0.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rifin_STEVOR PF02009.11 KXX72847.1 - 0.075 12.6 1.8 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Rifin/stevor family IF4E PF01652.13 KXX72849.1 - 4.7e-39 133.5 0.4 6e-39 133.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NPV_P10 PF05531.7 KXX72851.1 - 0.1 12.8 1.1 5.5 7.3 0.7 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Form_Nir_trans PF01226.12 KXX72852.1 - 1.1e-69 234.1 13.5 1.3e-69 233.8 9.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Spore_YtrH PF14034.1 KXX72852.1 - 0.0061 16.4 0.3 0.14 12.0 0.0 2.5 2 1 0 2 2 2 1 Sporulation protein YtrH Cu-oxidase_3 PF07732.10 KXX72853.1 - 4e-14 52.3 0.0 4.1e-09 36.1 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX72853.1 - 1.2e-10 41.0 0.1 0.00026 20.4 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KXX72853.1 - 3.3e-05 23.7 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.15 KXX72853.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family HLH PF00010.21 KXX72854.1 - 1.5e-12 46.9 0.8 1.5e-12 46.9 0.5 2.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Taxilin PF09728.4 KXX72854.1 - 0.00086 18.4 5.9 0.0012 18.0 4.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1664 PF07889.7 KXX72854.1 - 0.014 15.1 0.5 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 KXX72854.1 - 0.017 14.9 4.3 0.034 13.9 2.7 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.4 KXX72854.1 - 0.022 13.9 3.2 0.034 13.3 2.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF641 PF04859.7 KXX72854.1 - 0.027 14.2 3.1 0.057 13.1 2.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 KXX72854.1 - 0.048 14.0 3.5 0.062 13.6 0.4 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.10 KXX72854.1 - 0.057 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX72854.1 - 0.096 12.2 7.5 0.057 13.0 3.7 1.6 1 1 0 1 1 1 0 IncA protein Nnf1 PF03980.9 KXX72854.1 - 0.13 12.2 3.3 0.34 10.9 2.3 1.8 1 0 0 1 1 1 0 Nnf1 FliJ PF02050.11 KXX72854.1 - 0.22 11.6 6.0 0.74 9.8 4.1 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein Fib_alpha PF08702.5 KXX72854.1 - 0.23 11.5 4.7 0.77 9.8 3.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 KXX72854.1 - 0.29 11.0 8.0 0.66 9.8 5.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KXX72854.1 - 0.63 8.9 10.8 1.7 7.5 7.5 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hydrolase_6 PF13344.1 KXX72855.1 - 8.1e-30 102.6 0.0 1.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX72855.1 - 5.6e-14 53.0 0.0 8.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX72855.1 - 4.8e-11 42.2 0.0 2.2e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KXX72855.1 - 1.1e-05 25.7 0.0 0.0063 16.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX72855.1 - 0.11 12.6 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KXX72855.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SET PF00856.23 KXX72856.1 - 1.3e-07 32.0 0.0 9.2e-06 26.0 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 KXX72856.1 - 0.14 11.7 1.3 4.9 6.8 0.8 2.6 2 0 0 2 2 2 0 TPR repeat MFS_1 PF07690.11 KXX72858.1 - 1.8e-31 109.1 33.0 2.3e-31 108.8 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX72858.1 - 1.6e-19 69.5 15.5 1.9e-19 69.3 10.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX72858.1 - 5.9e-12 44.9 17.1 5.9e-12 44.9 11.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 KXX72860.1 - 8.4e-28 97.1 0.4 5.6e-15 54.8 0.1 2.2 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KXX72861.1 - 2.4e-43 148.3 0.0 3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KXX72862.1 - 6.8e-11 41.8 1.1 6.9e-11 41.8 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX72862.1 - 0.0009 18.9 0.5 0.0085 15.8 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TPR_10 PF13374.1 KXX72863.1 - 7.1e-24 82.9 3.1 3.8e-12 45.7 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX72863.1 - 2.8e-17 62.4 0.6 3.9e-17 61.9 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX72863.1 - 5.9e-08 32.2 3.0 7.5e-06 25.5 0.4 1.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KXX72863.1 - 1.8e-06 27.2 0.3 0.058 13.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX72863.1 - 3.8e-05 24.2 0.6 6.8e-05 23.4 0.4 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX72863.1 - 4.6e-05 23.4 2.0 0.0039 17.2 0.3 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KXX72863.1 - 4.9e-05 22.9 1.4 0.22 11.5 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX72863.1 - 0.00013 21.8 0.2 0.34 11.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 KXX72863.1 - 0.00016 21.3 0.2 0.55 10.0 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX72863.1 - 0.0032 17.1 2.7 0.95 9.4 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2508 PF10704.4 KXX72863.1 - 0.016 15.3 1.5 4.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) TPR_14 PF13428.1 KXX72863.1 - 0.023 15.2 0.9 7.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BEX PF04538.7 KXX72863.1 - 0.031 14.4 0.8 1.8 8.8 0.1 2.0 2 0 0 2 2 2 0 Brain expressed X-linked like family Pep3_Vps18 PF05131.9 KXX72863.1 - 0.067 12.6 0.1 7.1 6.0 0.0 2.0 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family TPR_19 PF14559.1 KXX72863.1 - 0.071 13.4 3.0 0.15 12.3 1.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF4003 PF13170.1 KXX72863.1 - 0.079 12.2 0.5 2.4 7.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) DUF3381 PF11861.3 KXX72863.1 - 0.086 12.3 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2353 PF09789.4 KXX72863.1 - 0.14 11.3 2.3 0.2 10.8 1.6 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TPR_21 PF09976.4 KXX72863.1 - 0.15 11.9 0.9 11 5.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat FliT PF05400.8 KXX72863.1 - 0.2 12.1 7.0 0.9 9.9 5.0 1.7 1 1 0 1 1 1 0 Flagellar protein FliT PspB PF06667.7 KXX72863.1 - 0.25 11.2 2.7 4.9 7.1 0.2 2.1 2 0 0 2 2 2 0 Phage shock protein B DUF2680 PF10925.3 KXX72863.1 - 0.99 9.3 5.1 7.3 6.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF919 PF06034.6 KXX72863.1 - 1.3 8.7 4.0 13 5.4 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Kinesin-relat_1 PF12711.2 KXX72863.1 - 1.8 9.0 7.0 11 6.4 0.5 2.1 1 1 0 2 2 2 0 Kinesin motor Calici_MSP PF05752.6 KXX72863.1 - 2 7.9 4.3 13 5.2 0.3 2.0 1 1 1 2 2 2 0 Calicivirus minor structural protein NYD-SP28_assoc PF14775.1 KXX72863.1 - 3.7 7.3 8.6 9.5 6.0 0.8 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain Nop10p PF04135.7 KXX72866.1 - 3e-18 65.2 0.1 3.3e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Bys1 PF04681.7 KXX72868.1 - 3.1e-14 52.9 0.0 3.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NOB1_Zn_bind PF08772.6 KXX72869.1 - 1.4e-31 108.1 4.6 2.4e-31 107.3 3.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KXX72869.1 - 0.00058 19.7 1.8 0.0014 18.5 1.2 1.6 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KXX72869.1 - 0.53 9.8 6.0 0.22 11.0 0.8 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Tannase PF07519.6 KXX72870.1 - 1.2e-97 327.5 0.0 3.1e-96 322.9 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 KXX72871.1 - 1.5e-29 102.8 29.7 1.5e-29 102.8 20.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CTP_synth_N PF06418.9 KXX72872.1 - 7.1e-113 376.2 0.1 9.5e-113 375.8 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KXX72872.1 - 1.5e-52 177.8 0.0 2.8e-52 176.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KXX72872.1 - 9.4e-06 25.2 0.0 2.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KXX72872.1 - 0.005 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_2 PF12796.2 KXX72873.1 - 4.5e-41 139.0 0.0 2.6e-09 37.2 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX72873.1 - 2.1e-37 125.0 7.6 1.3e-06 27.9 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KXX72873.1 - 1e-32 111.3 8.3 5.5e-07 29.6 0.0 7.6 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX72873.1 - 2e-31 107.7 0.1 3.2e-07 30.6 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX72873.1 - 8e-24 81.3 0.7 0.055 13.7 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat FCSD-flav_bind PF09242.6 KXX72875.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding PNP_UDP_1 PF01048.15 KXX72876.1 - 0.00017 20.6 2.7 0.001 18.1 1.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KXX72877.1 - 0.0038 16.8 0.1 0.012 15.3 0.1 1.7 1 1 1 2 2 2 1 NACHT domain RRM_1 PF00076.17 KXX72878.1 - 2.3e-09 36.7 0.1 6.6e-07 28.8 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX72878.1 - 7.3e-09 35.4 0.0 2.2e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX72878.1 - 0.00011 22.0 0.1 0.0017 18.1 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KXX72878.1 - 0.4 9.5 6.3 0.046 12.6 0.9 1.8 1 1 1 2 2 2 0 AAR2 protein Aldedh PF00171.17 KXX72879.1 - 2.3e-134 448.2 0.0 2.5e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX72879.1 - 1.4e-08 33.8 0.0 2.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) TPR_11 PF13414.1 KXX72881.1 - 1.6e-14 53.2 5.3 1.4e-13 50.2 1.4 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KXX72881.1 - 6.1e-10 38.2 0.5 0.00085 18.8 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX72881.1 - 5.2e-09 35.3 1.8 0.00058 19.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX72881.1 - 2e-06 27.6 2.1 2e-06 27.6 1.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX72881.1 - 4.1e-06 26.1 3.4 0.081 12.7 0.0 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX72881.1 - 0.00012 22.1 2.7 0.0002 21.4 1.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KXX72881.1 - 0.00047 20.4 0.9 0.0026 18.0 0.6 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX72881.1 - 0.00064 20.1 3.1 0.17 12.6 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX72881.1 - 0.002 18.7 6.5 0.0044 17.6 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX72881.1 - 0.05 14.0 2.0 27 5.4 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX72881.1 - 0.18 11.6 2.1 8.6 6.4 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KXX72881.1 - 0.45 10.4 9.3 0.48 10.3 0.5 3.4 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KXX72881.1 - 2 8.4 0.0 2 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat NMD3 PF04981.8 KXX72882.1 - 7.4e-72 241.2 1.9 9.8e-72 240.8 1.3 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KXX72882.1 - 0.25 11.3 4.1 0.28 11.1 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 KXX72882.1 - 3 7.7 5.6 10 6.0 1.6 2.3 2 0 0 2 2 2 0 FYVE zinc finger Peptidase_S8 PF00082.17 KXX72883.1 - 1.9e-16 60.0 3.3 2.6e-16 59.6 2.3 1.1 1 0 0 1 1 1 1 Subtilase family zf-C2H2_4 PF13894.1 KXX72885.1 - 0.014 15.6 14.2 2.2 8.7 0.8 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_fiss_reg PF05308.6 KXX72885.1 - 0.015 14.7 0.9 0.015 14.7 0.6 3.1 2 1 0 2 2 2 0 Mitochondrial fission regulator zf-met PF12874.2 KXX72885.1 - 0.041 14.0 2.6 0.41 10.9 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX72885.1 - 0.55 10.4 5.5 3 8.0 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KXX72885.1 - 7.1 7.2 10.8 9.3 6.8 0.3 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type Fungal_trans PF04082.13 KXX72886.1 - 1.3e-24 86.4 1.3 1.3e-24 86.4 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX72886.1 - 9.5e-08 31.8 12.7 1.7e-07 30.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KXX72887.1 - 8.4e-104 347.4 0.0 6.9e-103 344.4 0.0 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family E1-E2_ATPase PF00122.15 KXX72888.1 - 1.2e-14 53.9 0.0 1.5e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KXX72888.1 - 8e-14 51.3 0.0 2.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX72888.1 - 3.9e-11 43.4 0.0 1.1e-10 41.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX72888.1 - 9.4e-11 42.5 4.1 1.2e-08 35.6 2.8 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX72888.1 - 0.011 15.3 0.6 0.024 14.2 0.4 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 KXX72889.1 - 2.6e-28 96.8 5.7 8e-14 50.9 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Rax2 PF12768.2 KXX72889.1 - 0.00023 20.4 0.0 0.26 10.4 0.0 2.0 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Big_5 PF13205.1 KXX72889.1 - 0.011 16.3 1.7 0.65 10.6 0.4 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain Big_3_4 PF13754.1 KXX72889.1 - 0.027 14.7 2.1 0.39 11.0 1.1 2.6 1 1 2 3 3 3 0 Bacterial Ig-like domain (group 3) DUF1258 PF06869.7 KXX72889.1 - 0.038 13.0 0.0 1.6 7.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) dsrm PF00035.20 KXX72889.1 - 0.054 14.0 0.2 2.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF642 PF04862.7 KXX72889.1 - 0.06 12.9 0.1 0.097 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF642) GPI-anchored PF10342.4 KXX72889.1 - 0.082 13.3 3.0 0.81 10.2 1.0 2.1 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Nup160 PF11715.3 KXX72889.1 - 0.085 10.9 0.1 0.18 9.9 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1652 PF07865.6 KXX72889.1 - 0.14 11.8 0.0 9.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Kelch_6 PF13964.1 KXX72889.1 - 0.18 12.0 1.5 2.6 8.3 0.1 2.7 3 0 0 3 3 3 0 Kelch motif HATPase_c PF02518.21 KXX72890.1 - 4.7e-25 87.4 0.2 1e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KXX72890.1 - 1.2e-21 76.4 0.1 4.1e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KXX72890.1 - 1.3e-21 76.7 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KXX72890.1 - 2.7e-19 69.0 0.6 6.4e-11 42.2 0.1 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KXX72890.1 - 1.7e-12 47.5 0.0 1.8e-06 28.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 KXX72890.1 - 4.8e-07 29.5 0.0 0.031 14.0 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KXX72890.1 - 1.7e-06 28.0 0.5 6e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 KXX72890.1 - 0.015 15.1 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 PAS domain 2-Hacid_dh_C PF02826.14 KXX72891.1 - 3.6e-54 182.5 0.0 5.3e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX72891.1 - 3.6e-34 117.1 0.2 4.4e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KXX72891.1 - 0.0044 17.3 0.0 0.0099 16.1 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 KXX72891.1 - 0.024 14.4 0.3 0.049 13.4 0.0 1.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KXX72891.1 - 0.12 11.9 2.1 0.32 10.5 0.9 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF21 PF01595.15 KXX72892.1 - 1.9e-31 108.7 0.1 7.8e-31 106.7 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 KXX72892.1 - 4.3e-06 26.4 0.6 0.0071 16.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain Glyoxalase PF00903.20 KXX72893.1 - 1e-40 138.6 0.0 4.2e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX72893.1 - 3.9e-33 114.2 0.1 5.5e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KXX72893.1 - 1.7e-18 66.6 0.0 2.9e-08 33.6 0.0 4.0 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KXX72893.1 - 6.8e-06 26.0 0.0 0.21 11.4 0.0 3.2 1 1 2 3 3 3 3 Glyoxalase-like domain Tyrosinase PF00264.15 KXX72895.1 - 2.4e-55 188.1 0.7 2.4e-55 188.1 0.5 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Transpep_BrtH PF14399.1 KXX72896.1 - 4.5e-24 85.3 0.0 5.2e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase Peptidase_C39 PF03412.10 KXX72896.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Erv26 PF04148.8 KXX72897.1 - 6.8e-89 296.8 0.2 7.6e-89 296.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 KXX72897.1 - 0.02 14.5 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) QueT PF06177.6 KXX72897.1 - 0.033 14.1 1.5 0.062 13.2 1.0 1.4 1 0 0 1 1 1 0 QueT transporter Cytochrom_C_asm PF01578.15 KXX72897.1 - 0.035 13.6 0.2 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C assembly protein Claudin_2 PF13903.1 KXX72897.1 - 4.6 6.8 7.3 23 4.6 5.1 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction WBS_methylT PF12589.3 KXX72898.1 - 9.5e-17 61.2 6.7 1.7e-16 60.4 4.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KXX72898.1 - 1.1e-10 41.8 0.0 2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX72898.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX72898.1 - 4.6e-06 26.2 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX72898.1 - 8.4e-05 22.3 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KXX72898.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KXX72898.1 - 0.00019 21.8 0.0 0.00057 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX72898.1 - 0.00031 21.3 0.0 0.00064 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX72898.1 - 0.0022 17.1 0.0 0.023 13.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KXX72898.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX72898.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 KXX72899.1 - 2.4e-11 43.5 0.0 3.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sds3 PF08598.6 KXX72900.1 - 0.00089 18.8 2.2 0.0017 17.9 1.5 1.4 1 0 0 1 1 1 1 Sds3-like Rad60-SLD PF11976.3 KXX72900.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NOA36 PF06524.7 KXX72901.1 - 0.028 13.7 7.0 0.047 12.9 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 KXX72901.1 - 0.044 13.3 5.8 0.081 12.5 4.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KXX72901.1 - 0.11 12.2 5.1 0.3 10.8 3.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 KXX72901.1 - 0.31 10.2 6.8 0.45 9.7 4.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KXX72901.1 - 0.52 8.1 6.9 0.73 7.6 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KXX72901.1 - 2.7 5.9 5.2 4.4 5.2 3.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SnoaL_2 PF12680.2 KXX72903.1 - 3.1e-05 24.3 0.2 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain HTH_30 PF13556.1 KXX72905.1 - 0.033 13.7 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Beta-lactamase PF00144.19 KXX72906.1 - 6e-27 94.5 0.0 9.4e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_43 PF04616.9 KXX72907.1 - 1.4e-15 57.1 1.4 2.2e-15 56.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KXX72907.1 - 0.017 14.4 0.3 0.096 12.0 0.0 2.0 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain DUF1996 PF09362.5 KXX72908.1 - 6.2e-83 278.0 1.0 8e-83 277.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Swi3 PF07962.7 KXX72909.1 - 3.1e-29 100.4 0.1 7.3e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 MdcG PF10620.4 KXX72909.1 - 0.037 13.5 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Snf7 PF03357.16 KXX72910.1 - 2.7e-05 23.6 24.6 2.7e-05 23.6 17.0 1.5 1 1 0 1 1 1 1 Snf7 LCD1 PF09798.4 KXX72910.1 - 0.33 8.8 10.8 0.39 8.6 7.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein XLF PF09302.6 KXX72910.1 - 0.87 9.3 5.4 0.39 10.4 0.3 2.6 1 1 1 2 2 2 0 XLF (XRCC4-like factor) Bud13 PF09736.4 KXX72910.1 - 0.96 9.7 18.6 2.7 8.2 0.8 2.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex Tyrosinase PF00264.15 KXX72910.1 - 4 7.5 5.8 13 5.8 4.0 1.7 1 1 0 1 1 1 0 Common central domain of tyrosinase DSHCT PF08148.7 KXX72911.1 - 2.6e-61 205.9 0.4 5.1e-61 205.0 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KXX72911.1 - 5.8e-21 74.7 0.0 1.6e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX72911.1 - 4e-06 26.5 1.1 1.3e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KXX72911.1 - 0.043 12.9 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain Cut8_C PF08559.5 KXX72911.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Cut8 six-helix bundle NADH-u_ox-rdase PF10785.4 KXX72912.1 - 1e-35 121.8 0.5 1.7e-35 121.1 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KXX72912.1 - 6.8e-33 112.2 0.0 1.1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF427 PF04248.7 KXX72913.1 - 4.6e-19 67.8 0.0 6.4e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.11 KXX72914.1 - 2.4e-47 161.3 37.6 2.4e-47 161.3 26.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX72914.1 - 1.8e-10 40.0 9.5 1.8e-10 40.0 6.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KXX72914.1 - 0.015 13.3 0.4 0.015 13.3 0.3 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF898 PF05987.8 KXX72915.1 - 0.0011 17.9 1.9 0.0011 17.9 1.3 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) VirB3 PF05101.8 KXX72915.1 - 0.76 9.7 5.8 3.7 7.6 0.2 2.5 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein PepSY_TM_2 PF13703.1 KXX72915.1 - 7.7 6.7 10.0 1.5 9.0 2.8 2.6 2 1 0 2 2 2 0 PepSY-associated TM helix F-box PF00646.28 KXX72916.1 - 0.00014 21.3 0.9 0.0004 19.9 0.6 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX72916.1 - 0.0037 16.9 0.1 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Mito_carr PF00153.22 KXX72918.1 - 3.1e-73 241.5 4.9 1.1e-24 85.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MBOAT PF03062.14 KXX72919.1 - 4.5e-25 88.4 22.1 4.5e-25 88.4 15.3 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KXX72919.1 - 2.7e-06 27.3 4.9 6.8e-06 26.0 3.4 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L18e PF00828.14 KXX72920.1 - 1.5e-26 93.3 0.1 1.5e-26 93.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 KXX72921.1 - 7.4e-12 44.7 0.0 9.4e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX72921.1 - 4e-08 33.1 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX72921.1 - 6.6e-08 32.2 0.0 9.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX72921.1 - 0.0002 21.0 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PRP38_assoc PF12871.2 KXX72921.1 - 4.1 7.9 50.4 0.082 13.4 28.4 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3827 PF12877.2 KXX72921.1 - 6 4.8 6.6 6.4 4.7 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) FtsJ PF01728.14 KXX72922.1 - 2.6e-58 197.0 0.0 7.3e-58 195.5 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KXX72922.1 - 0.007 16.9 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF3092 PF11289.3 KXX72923.1 - 0.0024 17.1 6.6 1.1 8.3 0.6 3.5 1 1 3 4 4 4 3 Protein of unknown function (DUF3092) EF-hand_like PF09279.6 KXX72923.1 - 0.017 15.0 5.9 6.4 6.8 0.2 3.8 1 1 2 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3519 PF12033.3 KXX72923.1 - 0.019 15.1 8.8 24 5.1 0.2 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3519) DUF4093 PF13331.1 KXX72923.1 - 0.02 15.1 4.6 0.15 12.2 0.3 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4093) NTR PF01759.16 KXX72923.1 - 0.085 12.4 1.9 8.9 5.9 0.1 3.3 1 1 3 4 4 4 0 UNC-6/NTR/C345C module Arc_PepC_II PF06847.6 KXX72923.1 - 0.66 10.4 10.2 7 7.1 0.9 3.1 1 1 3 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II HTH_37 PF13744.1 KXX72923.1 - 8.6 6.2 13.0 72 3.2 0.1 5.5 2 1 4 6 6 6 0 Helix-turn-helix domain DUF3328 PF11807.3 KXX72924.1 - 0.00019 21.2 3.7 0.00053 19.7 2.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Neurensin PF14927.1 KXX72924.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Neurensin GFA PF04828.9 KXX72925.1 - 4.9e-06 26.3 0.6 4.9e-06 26.3 0.4 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 KXX72925.1 - 0.036 13.5 0.9 0.036 13.5 0.6 2.5 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 KXX72925.1 - 0.073 12.3 0.4 0.073 12.3 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain DUF2318 PF10080.4 KXX72925.1 - 0.52 10.1 4.7 0.29 10.9 0.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) TATR PF03430.8 KXX72927.1 - 0.083 11.5 1.1 0.12 10.9 0.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PGC7_Stella PF15549.1 KXX72927.1 - 2.2 8.2 4.9 0.87 9.5 0.6 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain DTHCT PF08070.6 KXX72927.1 - 2.4 8.8 12.2 0.56 10.8 3.7 3.0 3 0 0 3 3 3 0 DTHCT (NUC029) region DUF2347 PF09804.4 KXX72928.1 - 3.1e-105 351.4 0.0 3.9e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KXX72928.1 - 8.1e-49 166.0 0.0 1.6e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KXX72928.1 - 7.5e-06 25.6 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KXX72928.1 - 0.012 14.1 0.0 0.097 11.1 0.0 2.0 2 0 0 2 2 2 0 Transport protein Avl9 WD40 PF00400.27 KXX72929.1 - 3.3e-62 204.2 7.3 3.7e-11 42.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.5 KXX72929.1 - 2.3e-27 94.9 8.7 3.6e-27 94.3 6.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KXX72929.1 - 0.00034 18.8 0.4 0.047 11.8 0.0 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX72929.1 - 0.00068 18.4 0.1 0.25 10.0 0.0 3.2 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 KXX72929.1 - 0.0069 14.7 0.0 0.42 8.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 KXX72929.1 - 0.053 12.9 0.7 0.52 9.7 0.4 2.5 1 1 2 3 3 3 0 PQQ-like domain Nbas_N PF15492.1 KXX72929.1 - 0.06 12.4 0.0 14 4.6 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.7 KXX72930.1 - 3.7e-10 39.6 0.0 9.7e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX72930.1 - 4.5e-07 30.0 0.0 0.00012 22.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KXX72930.1 - 4.8e-06 26.6 0.1 4e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KXX72930.1 - 0.0007 19.1 0.1 0.015 14.7 0.0 2.8 4 0 0 4 4 4 1 AAA-like domain AAA_29 PF13555.1 KXX72930.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KXX72930.1 - 0.026 13.3 0.2 0.32 9.8 0.2 2.6 1 1 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KXX72930.1 - 0.029 14.6 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 KXX72930.1 - 0.043 13.6 2.7 2.4 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KXX72930.1 - 0.076 13.8 0.1 0.63 10.8 0.0 2.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KXX72930.1 - 0.086 13.1 0.1 1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KXX72930.1 - 0.11 12.7 1.2 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KXX72930.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase E1-E2_ATPase PF00122.15 KXX72931.1 - 1.1e-53 181.6 0.5 1.1e-53 181.6 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX72931.1 - 1.5e-43 148.4 6.2 5.3e-43 146.6 2.4 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KXX72931.1 - 1e-19 70.2 0.0 2.5e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KXX72931.1 - 2.2e-18 67.4 0.0 7.9e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX72931.1 - 8.2e-08 32.6 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX72931.1 - 0.021 14.2 0.2 0.13 11.7 0.0 2.5 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KXX72931.1 - 0.023 14.2 0.1 7.9 5.9 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 KXX72931.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) DUF202 PF02656.10 KXX72931.1 - 0.57 10.4 2.6 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3659 PF12396.3 KXX72934.1 - 8.4e-104 339.2 48.6 6.6e-24 83.3 0.8 5.2 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) GCV_T_C PF08669.6 KXX72934.1 - 0.014 15.3 1.6 36 4.4 0.0 4.8 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.3 KXX72935.1 - 2.4e-15 55.9 2.4 2.2e-10 40.0 0.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) ORC6 PF05460.8 KXX72935.1 - 0.29 10.2 5.0 0.39 9.7 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Thyroglobulin_1 PF00086.13 KXX72936.1 - 0.099 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Fungal_trans_2 PF11951.3 KXX72937.1 - 0.04 12.5 0.8 0.25 9.9 0.0 2.0 1 1 0 2 2 2 0 Fungal specific transcription factor domain DUF4554 PF15091.1 KXX72938.1 - 0.025 13.3 3.5 0.032 12.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CHCH PF06747.8 KXX72939.1 - 8.6e-07 28.7 6.0 1.4e-06 28.0 4.1 1.3 1 0 0 1 1 1 1 CHCH domain DUF2360 PF10152.4 KXX72939.1 - 7.6 6.8 17.6 9 6.5 3.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) COX14 PF14880.1 KXX72940.1 - 8.3e-18 63.7 1.7 8.3e-18 63.7 1.2 2.5 2 0 0 2 2 2 1 Cytochrome oxidase c assembly MSP1_C PF07462.6 KXX72940.1 - 2.7 6.2 9.9 3 6.1 0.8 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L50 PF10501.4 KXX72943.1 - 1.7e-21 76.2 0.0 3.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S RIB43A PF05914.7 KXX72943.1 - 0.034 12.7 2.9 0.05 12.2 2.0 1.1 1 0 0 1 1 1 0 RIB43A Ribosomal_L13e PF01294.13 KXX72944.1 - 2.4e-64 216.0 3.2 3.1e-64 215.7 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Rtt102p PF09510.5 KXX72944.1 - 0.019 14.9 0.1 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein TPR_10 PF13374.1 KXX72946.1 - 7.9e-40 133.6 1.0 4e-11 42.4 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX72946.1 - 4.1e-24 84.3 1.1 6.2e-15 54.9 0.0 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX72946.1 - 1.8e-10 39.8 0.1 0.0049 16.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KXX72946.1 - 4.2e-09 35.9 0.3 0.19 12.2 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX72946.1 - 3.6e-07 29.8 0.0 0.14 12.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX72946.1 - 5.9e-07 28.9 0.8 0.51 10.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX72946.1 - 4.3e-06 26.8 2.1 13 6.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NB-ARC PF00931.17 KXX72946.1 - 1.3e-05 24.2 0.0 3.1e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 KXX72946.1 - 4.8e-05 22.7 0.1 0.44 10.2 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX72946.1 - 0.00029 20.3 0.2 0.12 12.0 0.1 3.1 1 1 2 3 3 3 2 TPR repeat NACHT PF05729.7 KXX72946.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 KXX72946.1 - 0.00091 19.8 0.3 1 10.1 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX72946.1 - 0.0018 17.9 0.0 2.2 8.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX72946.1 - 0.0049 17.1 0.2 4.2 7.7 0.0 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 KXX72946.1 - 0.076 13.0 0.0 42 4.2 0.0 3.2 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_6 PF13174.1 KXX72946.1 - 0.43 11.1 3.0 16 6.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NDUF_B8 PF05821.6 KXX72947.1 - 0.00011 21.9 0.3 0.00017 21.3 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) MFS_1 PF07690.11 KXX72948.1 - 3.5e-40 137.7 64.5 5.5e-39 133.8 39.8 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX72948.1 - 8.5e-10 37.4 26.6 1.2e-09 36.9 18.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 KXX72948.1 - 1.8 9.0 4.5 36 4.8 0.2 3.8 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Adipogenin PF15202.1 KXX72948.1 - 4.7 7.1 8.8 4.2 7.3 0.0 3.8 4 0 0 4 4 4 0 Adipogenin APH PF01636.18 KXX72951.1 - 5.9e-15 55.6 0.3 7e-09 35.7 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX72951.1 - 2.6e-09 36.9 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KXX72951.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.15 KXX72951.1 - 0.1 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase p450 PF00067.17 KXX72952.1 - 2e-63 214.5 0.0 2.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 KXX72953.1 - 1.6e-41 142.0 4.6 2.6e-41 141.3 3.2 1.3 1 1 0 1 1 1 1 Pectate lyase RabGAP-TBC PF00566.13 KXX72954.1 - 1.2e-32 113.1 0.0 2.1e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_tranf_2_3 PF13641.1 KXX72955.1 - 2.6e-23 83.0 0.1 3.7e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KXX72955.1 - 4.1e-10 39.2 0.0 6.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX72955.1 - 4.1e-06 26.5 0.0 1.8e-05 24.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.5 KXX72955.1 - 0.014 14.5 1.1 0.014 14.5 0.1 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain BCS1_N PF08740.6 KXX72956.1 - 9.4e-44 149.2 1.0 1.3e-43 148.8 0.7 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KXX72956.1 - 1.6e-16 60.6 0.0 1.3e-07 31.8 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX72956.1 - 0.00097 19.9 0.0 0.0025 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX72956.1 - 0.0013 17.8 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KXX72956.1 - 0.0043 16.4 0.0 0.0094 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX72956.1 - 0.024 14.3 0.0 0.089 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX72956.1 - 0.11 12.4 0.6 0.67 9.9 0.1 2.3 1 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 KXX72956.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC Tau95 PF09734.4 KXX72957.1 - 3.6e-70 236.7 0.0 4.9e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CDC27 PF09507.5 KXX72957.1 - 1.7 7.8 17.6 3.2 6.8 12.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NAP PF00956.13 KXX72958.1 - 3.3e-42 144.2 0.3 4.1e-42 143.9 0.2 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF1949 PF09186.6 KXX72958.1 - 0.11 12.0 0.3 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) Asparaginase PF00710.15 KXX72959.1 - 1.3e-100 336.3 0.0 1.7e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 KXX72959.1 - 3.3e-09 36.0 0.7 2e-05 24.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KXX72959.1 - 7.4e-08 32.6 0.1 1.5e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX72959.1 - 1.9e-05 24.7 0.1 0.0001 22.4 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX72959.1 - 3.9e-05 24.0 0.5 0.0002 21.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2461 PF09365.5 KXX72960.1 - 8.9e-64 214.7 0.1 3.4e-63 212.8 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF4521 PF15021.1 KXX72963.1 - 0.033 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Ank_2 PF12796.2 KXX72964.1 - 8.1e-56 186.3 7.3 2.2e-15 56.7 0.6 6.4 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX72964.1 - 2e-54 178.8 18.9 4.2e-09 35.7 0.0 11.9 11 1 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KXX72964.1 - 8e-49 162.5 12.0 8.6e-11 41.7 0.3 9.7 5 2 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX72964.1 - 1.7e-44 145.3 9.6 0.00018 21.4 0.0 11.5 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 KXX72964.1 - 2.4e-41 139.3 8.9 7.8e-09 35.8 0.0 8.8 5 3 4 10 10 10 8 Ankyrin repeats (many copies) DUF2384 PF09722.5 KXX72964.1 - 0.044 13.6 0.1 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) CDO_I PF05995.7 KXX72965.1 - 1.9e-05 23.9 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KXX72965.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) MFS_1 PF07690.11 KXX72966.1 - 2.7e-24 85.5 35.6 5.4e-24 84.5 24.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX72966.1 - 2e-16 59.3 10.0 2.5e-16 59.0 6.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX72966.1 - 3.8e-09 35.6 12.1 3.8e-09 35.6 8.4 1.6 1 1 0 2 2 2 1 Sugar (and other) transporter DUF1700 PF08006.6 KXX72966.1 - 9.8 5.4 9.0 0.54 9.5 1.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Ank_2 PF12796.2 KXX72967.1 - 2.7e-12 46.8 0.0 2.1e-05 24.7 0.0 5.5 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX72967.1 - 1.9e-11 43.1 1.3 0.14 12.0 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KXX72967.1 - 2.1e-08 33.6 0.0 20 5.8 0.0 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.1 KXX72967.1 - 0.066 13.4 0.6 58 4.1 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) p450 PF00067.17 KXX72968.1 - 2.9e-74 250.2 0.0 3.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.23 KXX72970.1 - 2.2e-15 57.3 0.0 4.1e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 SET domain DUF829 PF05705.9 KXX72971.1 - 1.1e-69 234.7 0.0 1.3e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Metallophos_2 PF12850.2 KXX72972.1 - 0.071 12.9 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Hexokinase_2 PF03727.11 KXX72973.1 - 1e-33 116.5 0.0 8.6e-31 106.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KXX72973.1 - 7.8e-30 103.7 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Noggin PF05806.7 KXX72973.1 - 0.0042 16.4 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Noggin Glucosamine_iso PF01182.15 KXX72974.1 - 3.3e-27 95.4 0.0 5.9e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BAF1_ABF1 PF04684.8 KXX72974.1 - 3.2 6.4 9.3 7.1 5.3 6.5 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NDT80_PhoG PF05224.7 KXX72975.1 - 2.4e-34 118.9 0.0 5.5e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Dicty_REP PF05086.7 KXX72975.1 - 5.4 4.6 4.1 7.6 4.1 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cullin PF00888.17 KXX72977.1 - 7.3e-55 186.6 0.0 1.2e-54 185.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KXX72977.1 - 1.1e-21 76.7 0.1 2.4e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 KXX72977.1 - 0.0074 15.9 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator BLOC1_2 PF10046.4 KXX72978.1 - 0.016 15.2 0.7 0.62 10.2 0.0 4.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KXX72978.1 - 0.026 14.3 0.5 9.2 6.0 0.1 4.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2422 PF10337.4 KXX72978.1 - 0.049 12.4 0.0 8.8 4.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) DUF148 PF02520.12 KXX72978.1 - 0.1 12.4 0.7 0.97 9.2 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function DUF148 7tm_7 PF08395.7 KXX72980.1 - 0.05 12.6 3.3 0.07 12.1 2.3 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF4349 PF14257.1 KXX72980.1 - 2.3 7.3 5.7 3.3 6.8 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TPR_10 PF13374.1 KXX72981.1 - 1.6e-15 56.4 0.0 8.6e-07 28.6 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX72981.1 - 2.6e-13 49.6 1.4 7.7e-13 48.1 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat NB-ARC PF00931.17 KXX72981.1 - 9.1e-10 37.8 0.0 1.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 KXX72981.1 - 1.8e-06 27.2 0.1 0.037 13.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_22 PF13401.1 KXX72981.1 - 3.5e-06 27.1 0.0 1.5e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 KXX72981.1 - 7.1e-06 25.5 0.1 0.018 14.9 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF676 PF05057.9 KXX72981.1 - 6.8e-05 22.2 0.0 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) TPR_4 PF07721.9 KXX72981.1 - 0.00065 19.8 0.0 1.3 9.6 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat PGAP1 PF07819.8 KXX72981.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein TPR_1 PF00515.23 KXX72981.1 - 0.0012 18.3 0.0 1.1 9.0 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX72981.1 - 0.0013 19.3 0.0 0.0065 17.1 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX72981.1 - 0.0026 17.3 0.0 0.0092 15.6 0.0 2.0 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 KXX72981.1 - 0.0035 17.8 1.4 11 6.9 0.0 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX72981.1 - 0.0087 15.7 0.0 0.73 9.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX72981.1 - 0.019 15.2 0.1 0.07 13.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX72981.1 - 0.054 13.7 0.0 7.7 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_16 PF13191.1 KXX72981.1 - 0.068 13.1 1.6 0.15 11.9 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Abhydrolase_2 PF02230.11 KXX72981.1 - 0.17 11.2 0.0 0.82 9.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Git3 PF11710.3 KXX72982.1 - 2e-58 197.2 16.5 3.3e-58 196.5 11.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KXX72982.1 - 7.7e-28 96.0 0.0 7.7e-28 96.0 0.0 3.6 4 0 0 4 4 4 1 G protein-coupled glucose receptor regulating Gpa2 C-term Antimicrobial10 PF08105.6 KXX72982.1 - 0.081 12.5 0.9 0.24 11.0 0.2 2.0 2 0 0 2 2 2 0 Metchnikowin family Mucin PF01456.12 KXX72982.1 - 0.4 10.4 51.6 0.057 13.1 30.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Clp1 PF06807.9 KXX72983.1 - 2.3e-25 89.4 0.0 3.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KXX72983.1 - 1.9e-05 24.4 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KXX72983.1 - 0.0054 16.6 0.0 0.041 13.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KXX72983.1 - 0.0099 15.7 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KXX72983.1 - 0.035 13.1 0.1 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_16 PF13191.1 KXX72983.1 - 0.046 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KXX72983.1 - 0.13 11.9 0.0 0.78 9.3 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 KXX72983.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX72983.1 - 0.17 11.6 3.1 0.6 9.8 0.7 2.3 2 0 0 2 2 2 0 Part of AAA domain IPK PF03770.11 KXX72984.1 - 5.3e-51 173.0 0.0 7.4e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KXX72985.1 - 6.7e-15 54.8 0.1 7.3e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Arb1 PF09692.5 KXX72986.1 - 1.9e-26 92.8 0.1 2.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DNA_binding_1 PF01035.15 KXX72987.1 - 1.7e-24 85.3 0.0 2.4e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CDC45 PF02724.9 KXX72988.1 - 1 7.2 2.8 1.4 6.8 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ubiquitin PF00240.18 KXX72989.1 - 7.6e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family MIP-T3 PF10243.4 KXX72989.1 - 0.55 8.6 21.5 0.68 8.3 14.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Exo_endo_phos PF03372.18 KXX72990.1 - 9.2e-11 42.1 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nop PF01798.13 KXX72991.1 - 6.9e-53 177.9 1.2 1.3e-52 177.1 0.8 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KXX72991.1 - 1.1e-25 89.1 0.0 2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain adh_short PF00106.20 KXX72993.1 - 1.4e-24 86.8 0.1 5.4e-24 84.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX72993.1 - 1.4e-09 38.1 0.0 2e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX72993.1 - 1.9e-09 37.4 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX72993.1 - 0.0043 17.0 0.2 0.0072 16.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX72993.1 - 0.024 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 KXX72993.1 - 0.028 14.0 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus DAO PF01266.19 KXX72993.1 - 0.06 12.2 0.2 0.082 11.7 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 KXX72993.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 KXX72994.1 - 1.4e-33 116.1 0.0 1.6e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX72994.1 - 2.5e-10 40.6 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX72994.1 - 0.0073 15.0 0.0 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KXX72994.1 - 0.011 15.6 1.0 0.017 15.0 0.7 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KXX72994.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KXX72994.1 - 0.054 13.7 0.1 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.1 KXX72996.1 - 1.3e-17 64.5 0.2 1.6e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX72996.1 - 4.9e-13 49.4 0.1 6.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PFL PF02901.10 KXX72996.1 - 0.092 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase Glyco_hydro_61 PF03443.9 KXX72997.1 - 1.4e-67 227.6 0.0 2.1e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 KXX72998.1 - 1.3e-19 70.0 0.0 2.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX72998.1 - 4.1e-09 36.1 8.5 7.2e-09 35.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence PF06911.7 KXX72999.1 - 2.8e-49 167.2 3.5 5.4e-49 166.2 2.4 1.5 1 0 0 1 1 1 1 Senescence-associated protein PQQ_3 PF13570.1 KXX72999.1 - 0.027 14.7 0.4 0.14 12.4 0.3 2.3 1 0 0 1 1 1 0 PQQ-like domain Spc97_Spc98 PF04130.8 KXX73000.1 - 2.2e-66 224.3 0.0 3.5e-66 223.6 0.0 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family Glyco_hydro_18 PF00704.23 KXX73001.1 - 0.0077 15.7 0.0 0.0089 15.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 KXX73002.1 - 4.3e-22 78.2 0.0 5.3e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prenyltrans_1 PF13243.1 KXX73003.1 - 1.2e-09 38.1 0.0 0.009 16.0 0.0 4.0 3 0 0 3 3 3 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 KXX73003.1 - 1.1e-08 35.4 2.7 0.053 13.9 0.0 5.2 3 2 2 5 5 5 3 Prenyltransferase-like CVNH PF08881.5 KXX73004.1 - 6.6e-19 68.0 0.1 1.7e-11 44.2 0.1 2.4 2 1 0 2 2 2 2 CVNH domain MVL PF12151.3 KXX73004.1 - 0.012 15.2 0.2 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Mannan-binding protein Metallophos PF00149.23 KXX73006.1 - 3.5e-13 49.4 0.0 7.2e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KXX73006.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 KXX73007.1 - 1.9e-19 69.1 2.6 4.3e-19 68.0 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1777 PF08648.7 KXX73007.1 - 1.1e-05 25.2 26.6 1.1e-05 25.2 18.4 5.0 4 1 1 5 5 5 1 Protein of unknown function (DUF1777) RNA_pol PF00940.14 KXX73009.1 - 1.3e-166 554.0 0.0 2.6e-166 553.1 0.0 1.5 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KXX73009.1 - 2.5e-77 260.2 0.2 8.5e-77 258.5 0.1 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DctM PF06808.7 KXX73009.1 - 0.35 9.3 1.2 0.52 8.8 0.8 1.1 1 0 0 1 1 1 0 DctM-like transporters DHHA2 PF02833.9 KXX73010.1 - 4.9e-24 84.9 0.0 7.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KXX73010.1 - 1.5e-07 31.1 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 DHH family Oligomerisation PF02410.10 KXX73011.1 - 6.2e-06 26.1 0.0 4.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Oligomerisation domain SH3_3 PF08239.6 KXX73012.1 - 0.039 14.1 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Bacterial SH3 domain Glyco_hydro_47 PF01532.15 KXX73013.1 - 1.1e-134 449.4 0.0 1.4e-134 449.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_3 PF00933.16 KXX73014.1 - 7.2e-59 199.2 0.0 1.1e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX73014.1 - 4.3e-52 176.8 0.4 7.4e-52 176.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX73014.1 - 3.2e-24 84.6 1.0 3.2e-24 84.6 0.7 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 KXX73014.1 - 0.009 16.0 2.5 0.027 14.4 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.6 KXX73014.1 - 0.042 13.9 0.2 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 CARDB Sugar-bind PF04198.8 KXX73014.1 - 0.072 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain DUF3255 PF11631.3 KXX73014.1 - 0.079 12.5 0.2 0.34 10.5 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3255) Con-6 PF10346.4 KXX73015.1 - 1.8e-33 113.6 2.7 7.1e-17 60.5 0.4 2.4 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 KXX73015.1 - 0.0038 17.0 0.3 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Putative toxin 52 HET PF06985.6 KXX73016.1 - 4.2e-23 82.0 5.7 1.6e-19 70.4 0.4 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.2 KXX73017.1 - 1.8e-22 79.3 1.6 3.6e-22 78.3 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) GMC_oxred_N PF00732.14 KXX73018.1 - 3.4e-58 197.1 0.0 4.9e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73018.1 - 1.2e-30 106.6 0.2 2.1e-30 105.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KXX73018.1 - 5.1e-06 25.6 0.0 9.5e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX73018.1 - 0.0019 18.1 0.0 0.0063 16.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX73018.1 - 0.0048 15.7 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX73018.1 - 0.0069 16.4 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX73018.1 - 0.018 13.9 0.1 0.078 11.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KXX73018.1 - 0.022 13.8 0.1 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KXX73018.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box PF00646.28 KXX73019.1 - 0.00089 18.8 0.1 0.0022 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX73019.1 - 0.0026 17.4 0.9 0.0043 16.7 0.1 1.8 2 0 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.16 KXX73020.1 - 2.8e-51 174.0 0.0 3.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 KXX73021.1 - 2.9e-05 23.3 0.0 5.9e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Sec2p PF06428.6 KXX73023.1 - 1.4e-27 95.5 13.5 1.4e-27 95.5 9.4 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 KXX73023.1 - 3.9e-05 21.2 18.9 5.3e-05 20.7 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Med9 PF07544.8 KXX73023.1 - 1.1 9.0 12.9 2.8 7.7 0.1 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HLH PF00010.21 KXX73024.1 - 9.4e-19 66.8 0.1 2e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM220 PF15487.1 KXX73024.1 - 0.053 12.8 9.4 0.079 12.3 6.6 1.1 1 0 0 1 1 1 0 FAM220 family DMPK_coil PF08826.5 KXX73024.1 - 0.13 12.1 0.5 0.27 11.1 0.1 1.6 2 0 0 2 2 2 0 DMPK coiled coil domain like Oleosin PF01277.12 KXX73025.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Oleosin Yip1 PF04893.12 KXX73025.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain EphA2_TM PF14575.1 KXX73025.1 - 0.034 14.5 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PDGLE PF13190.1 KXX73025.1 - 0.12 12.0 0.4 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 PDGLE domain Gly-zipper_Omp PF13488.1 KXX73025.1 - 0.74 9.5 10.4 1.1 8.9 7.2 1.2 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.4 KXX73025.1 - 1.7 8.8 6.8 2.7 8.1 4.7 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 KXX73025.1 - 3 7.4 10.3 4.5 6.8 7.1 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Beta-APP PF03494.8 KXX73025.1 - 5.8 6.4 5.7 12 5.4 4.0 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) UCR_TM PF02921.9 KXX73027.1 - 9.9e-19 67.3 1.0 9.9e-19 67.3 0.7 1.6 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.4 KXX73028.1 - 2.3e-94 316.3 0.0 3.3e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KXX73028.1 - 6.5e-68 229.1 0.0 5.5e-66 222.8 0.0 3.1 3 0 0 3 3 3 1 CPSF A subunit region p450 PF00067.17 KXX73029.1 - 4.9e-36 124.2 0.1 2.9e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Asp_protease_2 PF13650.1 KXX73030.1 - 0.054 13.9 0.0 0.083 13.3 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease EPSP_synthase PF00275.15 KXX73034.1 - 6.2e-128 426.7 0.1 1.2e-127 425.8 0.1 1.5 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KXX73034.1 - 1.3e-99 332.3 0.0 2.3e-99 331.5 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KXX73034.1 - 2e-62 210.7 0.0 3.4e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KXX73034.1 - 5.2e-37 127.1 0.0 2.6e-35 121.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KXX73034.1 - 1.6e-24 85.7 0.0 4.1e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KXX73034.1 - 2.5e-11 43.8 0.0 8.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KXX73034.1 - 1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KXX73034.1 - 0.00016 22.4 0.0 0.00041 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AA_permease PF00324.16 KXX73035.1 - 4.3e-135 450.7 39.6 5.2e-135 450.4 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX73035.1 - 4.5e-39 134.1 45.0 5.5e-39 133.9 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease RVT_1 PF00078.22 KXX73036.1 - 5.7e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_11 PF13414.1 KXX73037.1 - 6.8e-22 76.8 14.7 4.2e-09 35.9 0.9 4.5 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 KXX73037.1 - 9.1e-21 72.0 13.4 1.7e-05 24.3 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KXX73037.1 - 1.1e-19 69.1 10.7 2e-06 27.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KXX73037.1 - 5.4e-17 61.9 11.9 5.3e-06 26.9 0.1 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73037.1 - 4.6e-15 54.7 15.5 0.00025 21.3 0.0 6.4 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73037.1 - 5.3e-15 54.2 7.7 0.0038 17.3 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KXX73037.1 - 6.6e-13 48.7 7.5 0.00037 20.7 3.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73037.1 - 4e-12 44.9 4.4 0.061 13.1 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KXX73037.1 - 1.1e-11 44.5 10.2 2.3e-06 27.4 0.7 4.4 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX73037.1 - 1.3e-11 43.4 3.0 0.01 15.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KXX73037.1 - 9.3e-10 38.2 3.7 0.0011 18.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KXX73037.1 - 2.5e-09 37.1 4.7 0.0064 16.5 0.0 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KXX73037.1 - 1.1e-07 31.7 3.5 0.45 11.0 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX73037.1 - 0.00018 21.5 4.6 0.013 15.5 0.3 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KXX73037.1 - 0.00034 19.7 1.9 0.31 10.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 KXX73037.1 - 0.033 14.2 2.2 0.085 12.9 0.4 2.3 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_3 PF07720.7 KXX73037.1 - 0.056 13.2 0.1 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KXX73037.1 - 0.32 10.9 4.1 2.8 7.8 0.3 3.6 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KXX73037.1 - 1.6 8.7 9.9 14 5.7 0.4 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.17 KXX73038.1 - 3.1e-34 116.4 0.0 1.3e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX73038.1 - 2.3e-26 91.5 0.0 5e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX73038.1 - 3.8e-15 55.4 0.0 5.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 KXX73039.1 - 1e-09 38.9 0.0 1.9e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KXX73039.1 - 4.6e-09 35.9 6.7 4.6e-09 35.9 4.6 2.3 2 0 0 2 2 2 1 MYND finger DUF2484 PF10658.4 KXX73039.1 - 0.055 13.5 0.5 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) RNase_T PF00929.19 KXX73040.1 - 3.6e-22 79.4 0.0 6.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Prefoldin PF02996.12 KXX73041.1 - 8.8e-25 86.6 0.5 1.1e-24 86.3 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KXX73041.1 - 0.0038 16.9 2.2 1 9.1 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 KXX73041.1 - 0.0051 16.7 0.3 0.0096 15.8 0.2 1.4 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Cytochrom_B561 PF03188.11 KXX73042.1 - 1.2e-05 25.1 6.5 1.4e-05 24.9 3.0 2.3 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4184 PF13803.1 KXX73042.1 - 0.0035 16.6 0.3 0.0068 15.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4184) PepSY_TM_2 PF13703.1 KXX73042.1 - 0.01 15.9 9.6 0.028 14.5 1.4 3.3 2 1 1 3 3 3 0 PepSY-associated TM helix DUF2306 PF10067.4 KXX73042.1 - 0.2 11.8 8.1 0.76 9.9 0.1 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Ferric_reduct PF01794.14 KXX73042.1 - 0.6 10.2 10.7 1.8 8.6 0.7 3.1 1 1 0 2 2 2 0 Ferric reductase like transmembrane component Cytochrom_B_N PF00033.14 KXX73042.1 - 1.1 8.5 13.1 2.4 7.4 7.4 2.6 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Glyco_hydro_43 PF04616.9 KXX73043.1 - 4.3e-12 45.7 7.4 2.5e-10 39.9 1.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Big_3 PF07523.7 KXX73043.1 - 4.9 7.2 7.0 15 5.7 0.1 3.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) MFS_1 PF07690.11 KXX73046.1 - 1.1e-23 83.5 53.5 4.5e-22 78.2 30.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KXX73047.1 - 8.6e-07 27.9 2.2 9.2e-07 27.8 1.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73047.1 - 0.073 11.6 0.9 0.081 11.4 0.7 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter PLDc_N PF13396.1 KXX73047.1 - 5.3 6.7 9.7 28 4.4 6.7 2.2 1 1 0 1 1 1 0 Phospholipase_D-nuclease N-terminal HI0933_like PF03486.9 KXX73048.1 - 0.003 16.0 0.1 0.0041 15.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KXX73048.1 - 0.0038 17.1 0.2 0.0072 16.2 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73048.1 - 0.0075 15.1 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX73048.1 - 0.013 14.4 0.0 0.034 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX73048.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX73048.1 - 0.061 13.3 0.1 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX73048.1 - 0.072 12.0 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KXX73048.1 - 0.087 11.6 0.2 0.13 11.0 0.1 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KXX73048.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KXX73048.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.21 KXX73049.1 - 0.0026 17.3 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.1 KXX73050.1 - 2.4e-21 76.3 0.0 3.3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX73050.1 - 4.2e-08 33.1 0.4 0.00041 20.2 0.4 2.8 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX73050.1 - 2e-06 27.4 0.2 0.0039 16.8 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KXX73050.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KXX73050.1 - 0.001 19.0 0.1 0.0097 15.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PALP PF00291.20 KXX73051.1 - 3.4e-53 180.8 0.1 4.3e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_pol_E_B PF04042.11 KXX73052.1 - 1.5e-52 177.9 0.0 1.9e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B WD40 PF00400.27 KXX73053.1 - 4.7e-32 108.7 12.4 9.9e-09 34.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 KXX73053.1 - 7.2e-19 67.5 0.1 1.2e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KXX73053.1 - 0.00021 19.5 1.8 0.086 10.9 0.2 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 tRNA-synt_1g PF09334.6 KXX73054.1 - 6.7e-115 383.8 0.2 1.2e-114 382.9 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KXX73054.1 - 1.4e-23 82.8 5.8 1.3e-09 36.6 0.0 4.0 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KXX73054.1 - 3.6e-09 36.1 0.0 0.00054 19.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KXX73054.1 - 0.0073 16.0 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DNA_pol_A_exo1 PF01612.15 KXX73055.1 - 1.5e-13 50.6 0.0 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 KXX73056.1 - 8e-21 73.3 0.1 9e-21 73.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 KXX73057.1 - 2.1e-37 128.6 26.1 2.1e-37 128.6 18.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Med10 PF09748.4 KXX73059.1 - 0.0067 16.2 0.6 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex Cob_adeno_trans PF01923.13 KXX73059.1 - 0.0092 15.7 7.6 0.057 13.2 0.1 3.7 2 2 2 4 4 4 1 Cobalamin adenosyltransferase MutS_III PF05192.13 KXX73059.1 - 0.018 14.7 0.2 0.062 13.0 0.1 1.9 1 1 0 1 1 1 0 MutS domain III V-SNARE PF05008.10 KXX73059.1 - 0.08 13.1 4.1 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus IPK PF03770.11 KXX73059.1 - 0.084 12.5 1.6 0.25 10.9 0.1 2.2 2 1 0 2 2 2 0 Inositol polyphosphate kinase DB PF01682.14 KXX73059.1 - 0.11 12.5 0.8 19 5.3 0.1 3.1 3 0 0 3 3 3 0 DB module NPV_P10 PF05531.7 KXX73059.1 - 0.21 11.8 2.0 0.49 10.6 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KXX73059.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.8 2 1 0 2 2 2 0 IncA protein PilO PF04350.8 KXX73059.1 - 0.23 11.3 2.1 6.3 6.6 0.1 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO RmuC PF02646.11 KXX73059.1 - 0.67 8.7 4.9 1 8.1 0.1 2.3 2 0 0 2 2 2 0 RmuC family Adeno_PIX PF03955.9 KXX73059.1 - 2.7 8.5 6.2 6.7 7.2 0.5 2.9 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) FAD_binding_3 PF01494.14 KXX73060.1 - 2.9e-06 26.5 3.9 0.049 12.6 0.4 3.4 3 1 1 4 4 4 2 FAD binding domain Pyr_redox PF00070.22 KXX73060.1 - 0.00081 19.7 1.8 0.0015 18.9 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX73060.1 - 0.0028 17.6 0.6 0.0074 16.2 0.4 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX73060.1 - 0.018 13.9 0.2 0.098 11.5 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX73060.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_2 PF13923.1 KXX73061.1 - 4.5e-10 39.3 9.8 7.6e-10 38.6 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX73061.1 - 2.2e-09 36.9 8.4 3.5e-09 36.3 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KXX73061.1 - 7e-09 35.2 7.7 1.1e-08 34.5 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX73061.1 - 1e-08 34.6 3.1 1.8e-08 33.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX73061.1 - 1.3e-07 31.1 6.0 2.2e-07 30.5 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KXX73061.1 - 0.00013 21.9 8.0 0.00038 20.5 5.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KXX73061.1 - 0.0014 18.3 4.2 0.0025 17.4 2.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KXX73061.1 - 0.0016 18.2 8.0 0.0027 17.5 5.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KXX73061.1 - 0.045 13.2 4.3 3.2 7.2 3.6 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 KXX73061.1 - 0.076 12.6 8.4 0.089 12.3 2.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KXX73061.1 - 0.078 12.5 6.8 0.15 11.6 4.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KXX73061.1 - 0.16 11.7 7.3 1.3 8.8 4.9 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Trm112p PF03966.11 KXX73061.1 - 0.28 11.5 0.1 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Trm112p-like protein zinc-ribbons_6 PF07191.7 KXX73061.1 - 0.84 9.4 4.8 3 7.7 3.3 2.0 1 1 1 2 2 2 0 zinc-ribbons Pkinase PF00069.20 KXX73062.1 - 1.2e-29 103.3 0.0 2.7e-29 102.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73062.1 - 3.9e-06 26.1 0.1 0.0013 17.8 0.0 2.7 4 0 0 4 4 4 2 Protein tyrosine kinase DUF2551 PF10826.3 KXX73062.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) CFEM PF05730.6 KXX73063.1 - 0.0058 16.4 4.9 0.0081 15.9 3.4 1.2 1 0 0 1 1 1 1 CFEM domain Brr6_like_C_C PF10104.4 KXX73065.1 - 3.5e-37 126.9 0.2 4.4e-37 126.5 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pkinase PF00069.20 KXX73066.1 - 3.6e-42 144.3 0.6 1.5e-25 89.8 0.2 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73066.1 - 2.3e-15 56.3 0.4 6.8e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KXX73066.1 - 0.067 11.9 0.0 0.9 8.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Med26 PF08711.6 KXX73067.1 - 1.9e-12 46.4 0.0 3.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain KR PF08659.5 KXX73069.1 - 1.1e-08 35.0 0.3 1.8e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX73069.1 - 0.0039 17.1 0.3 0.0077 16.1 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DUF1127 PF06568.6 KXX73069.1 - 0.24 10.8 1.6 0.3 10.5 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) PUF PF00806.14 KXX73073.1 - 1.2e-53 175.7 3.2 1.2e-08 33.9 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat WD40 PF00400.27 KXX73074.1 - 2e-23 81.3 16.4 8.7e-07 28.5 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ PF01011.16 KXX73074.1 - 0.097 12.2 2.1 6 6.5 0.1 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Asp PF00026.18 KXX73075.1 - 6.3e-71 239.2 0.1 7.6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX73075.1 - 1.2e-10 41.5 0.1 1.4e-09 38.1 0.0 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KXX73075.1 - 9.2e-07 29.2 2.8 0.024 15.1 0.5 3.9 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KXX73075.1 - 2.4e-05 23.9 0.0 5.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KXX73075.1 - 0.052 13.3 0.2 0.68 9.8 0.1 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease ATP-synt_C PF00137.16 KXX73076.1 - 4.9e-27 93.6 24.9 2.6e-16 59.2 7.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KXX73076.1 - 0.014 14.8 0.3 4.2 6.9 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF3816 PF12822.2 KXX73076.1 - 0.78 9.6 12.5 0.49 10.2 6.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Pep3_Vps18 PF05131.9 KXX73077.1 - 2.8e-48 163.0 0.0 7.1e-48 161.7 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KXX73077.1 - 1.1e-11 44.4 2.0 5.8e-08 32.4 0.0 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KXX73077.1 - 0.0045 16.7 1.4 0.0045 16.7 1.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KXX73077.1 - 0.01 15.5 1.5 0.01 15.5 1.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DNA_pol3_theta PF06440.6 KXX73077.1 - 0.02 14.4 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, theta subunit zf-rbx1 PF12678.2 KXX73077.1 - 0.033 14.2 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DinB_2 PF12867.2 KXX73077.1 - 0.04 14.2 0.4 1.7 8.9 0.0 3.3 3 1 0 3 3 3 0 DinB superfamily TPR_21 PF09976.4 KXX73077.1 - 0.068 13.1 0.1 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KXX73077.1 - 3.2 7.4 5.2 0.72 9.5 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF676 PF05057.9 KXX73079.1 - 0.00015 21.1 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KXX73079.1 - 0.00032 20.3 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_30 PF13604.1 KXX73079.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KXX73079.1 - 0.02 14.4 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 KXX73079.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 KXX73079.1 - 0.026 14.6 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 KXX73079.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family cobW PF02492.14 KXX73079.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KXX73079.1 - 0.097 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KXX73079.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KXX73079.1 - 0.15 12.2 0.1 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX73079.1 - 0.16 12.2 0.0 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KXX73079.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Acetyltransf_1 PF00583.19 KXX73080.1 - 2.7e-07 30.5 0.3 4.3e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX73080.1 - 0.00014 21.9 0.2 0.00025 21.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX73080.1 - 0.01 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 KXX73080.1 - 0.053 13.6 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX73080.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAN_4 PF14295.1 KXX73082.1 - 0.014 15.0 0.0 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 PAN domain p450 PF00067.17 KXX73083.1 - 9.7e-61 205.6 0.0 1.3e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 KXX73084.1 - 1.2e-18 66.9 1.6 1.2e-18 66.9 1.1 2.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family DUF3505 PF12013.3 KXX73085.1 - 4.9e-07 29.9 0.0 8.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Osteopontin PF00865.13 KXX73085.1 - 0.088 12.0 1.3 0.12 11.5 0.9 1.1 1 0 0 1 1 1 0 Osteopontin CENP-B_dimeris PF09026.5 KXX73085.1 - 0.29 11.3 3.0 0.64 10.2 2.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 KXX73085.1 - 4.3 7.8 13.6 6.6 7.2 4.8 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Helicase_C PF00271.26 KXX73086.1 - 1.5e-11 44.0 3.0 2.5e-11 43.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX73086.1 - 6.7e-06 25.6 0.0 0.0075 15.7 0.0 2.2 1 1 1 2 2 2 2 DEAD/DEAH box helicase Gly-zipper_OmpA PF13436.1 KXX73086.1 - 0.022 14.3 15.3 0.047 13.3 9.2 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 KXX73086.1 - 0.12 11.9 36.9 0.31 10.5 23.8 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KXX73086.1 - 2.8 7.6 39.0 13 5.5 0.0 3.6 2 1 0 2 2 2 0 Glycine zipper 2TM domain DUF1269 PF06897.7 KXX73086.1 - 5 7.2 10.2 1.4e+02 2.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) TraT PF05818.7 KXX73086.1 - 7.2 5.9 5.4 14 5.0 3.8 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2636 PF11120.3 KXX73087.1 - 0.16 11.5 1.9 9.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) DUF2673 PF10880.3 KXX73088.1 - 0.099 12.6 0.3 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Ank_2 PF12796.2 KXX73089.1 - 5.6e-72 238.1 0.0 4.9e-21 74.8 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73089.1 - 8.8e-71 230.4 0.0 1.7e-07 30.7 0.0 8.8 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 KXX73089.1 - 1e-47 155.3 0.0 0.00023 21.1 0.0 8.9 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KXX73089.1 - 1.1e-47 159.5 0.0 3.7e-11 43.2 0.0 5.9 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX73089.1 - 8.6e-45 149.7 0.0 9e-10 38.4 0.0 7.2 3 2 3 7 7 7 6 Ankyrin repeats (many copies) NB-ARC PF00931.17 KXX73089.1 - 2.5e-08 33.1 0.0 3.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 KXX73089.1 - 2.1e-06 27.8 0.0 6.9e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.1 KXX73089.1 - 0.00011 22.0 1.6 0.5 10.3 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 KXX73089.1 - 0.00076 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase TPR_2 PF07719.12 KXX73089.1 - 0.013 15.3 1.8 3.8 7.6 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DPRP PF04244.8 KXX73089.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein TPR_7 PF13176.1 KXX73089.1 - 0.023 14.4 0.3 3.2 7.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.1 KXX73089.1 - 0.027 14.6 0.2 0.082 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.23 KXX73089.1 - 0.048 13.2 0.3 9.8 5.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX73089.1 - 0.065 13.7 4.3 1.8 9.1 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat RecA PF00154.16 KXX73089.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TPR_14 PF13428.1 KXX73089.1 - 0.093 13.4 1.5 29 5.6 0.1 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Patatin PF01734.17 KXX73090.1 - 3e-14 53.4 0.2 3.2e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase DEAD PF00270.24 KXX73091.1 - 2.8e-45 153.8 0.0 7.5e-45 152.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 KXX73091.1 - 1e-22 79.6 1.4 2.4e-22 78.4 1.0 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KXX73091.1 - 3.3e-21 74.9 0.9 9.2e-21 73.4 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF202 PF02656.10 KXX73092.1 - 2.7e-07 30.7 3.2 2.1e-06 27.8 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4401 PF14351.1 KXX73092.1 - 0.0019 17.2 1.0 0.0021 17.1 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF4328 PF14219.1 KXX73092.1 - 0.023 13.9 1.7 0.026 13.8 0.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4328) UCR_Fe-S_N PF10399.4 KXX73092.1 - 0.036 13.2 0.1 0.036 13.2 0.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Transgly_assoc PF04226.8 KXX73092.1 - 0.075 13.1 0.6 0.075 13.1 0.4 1.8 3 0 0 3 3 3 0 Transglycosylase associated protein Tetraspannin PF00335.15 KXX73092.1 - 0.25 10.5 1.6 0.23 10.7 0.4 1.4 2 0 0 2 2 2 0 Tetraspanin family DUF2721 PF11026.3 KXX73092.1 - 1.5 8.4 7.1 0.41 10.2 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Claudin_2 PF13903.1 KXX73092.1 - 4.8 6.8 6.5 13 5.4 4.5 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DnaJ PF00226.26 KXX73094.1 - 3.3e-15 55.5 1.6 6.7e-15 54.5 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain IBR PF01485.16 KXX73095.1 - 5.4e-14 51.8 40.1 8.2e-10 38.4 5.1 3.4 3 0 0 3 3 3 2 IBR domain Arm PF00514.18 KXX73096.1 - 0.011 15.5 0.7 0.8 9.6 0.1 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CD99L2 PF12301.3 KXX73096.1 - 0.028 14.1 5.2 0.057 13.0 3.6 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 COPI_C PF06957.6 KXX73096.1 - 8.5 4.7 8.0 13 4.2 5.6 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Fungal_trans PF04082.13 KXX73097.1 - 9.6e-15 54.1 0.1 1.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KXX73097.1 - 8e-07 29.0 9.2 4e-05 23.6 1.7 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX73097.1 - 0.0016 18.6 6.1 0.0016 18.6 4.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KXX73097.1 - 0.0043 17.1 5.2 0.0085 16.2 3.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KXX73097.1 - 0.026 14.8 17.4 0.053 13.8 4.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type GDI PF00996.13 KXX73098.1 - 1.9e-143 477.9 0.0 2.3e-143 477.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KXX73098.1 - 0.015 15.3 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Erythro_esteras PF05139.9 KXX73098.1 - 0.067 12.3 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase MRP-L47 PF06984.8 KXX73099.1 - 4.8e-25 87.2 0.6 7.6e-25 86.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) C2 PF00168.25 KXX73104.1 - 4.7e-08 32.7 0.0 9.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 KXX73106.1 - 5e-67 225.7 0.0 7.8e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73106.1 - 2.5e-41 141.4 0.0 3.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX73106.1 - 4.2e-10 39.0 0.0 1.4e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KXX73106.1 - 0.014 14.4 0.3 0.031 13.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX73106.1 - 0.017 14.8 3.8 1.8 8.2 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Proteasome PF00227.21 KXX73107.1 - 5.7e-49 165.9 0.1 6.5e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.8 KXX73108.1 - 9e-28 96.0 0.1 1.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 KXX73108.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 The BURPS668_1122 family of deaminases Abhydrolase_4 PF08386.5 KXX73109.1 - 1.8e-22 79.1 0.0 3.2e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX73109.1 - 6.5e-12 45.4 0.0 5.7e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX73109.1 - 2.8e-10 40.4 0.1 7.5e-10 39.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX73109.1 - 0.0014 18.3 0.0 0.039 13.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family HD PF01966.17 KXX73110.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF2014 PF09427.5 KXX73111.1 - 5.1e-110 366.7 6.6 7.2e-110 366.2 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KXX73111.1 - 2.9e-17 62.0 0.8 5.7e-17 61.1 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4110 PF13422.1 KXX73111.1 - 0.046 13.5 0.5 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) FAD_binding_4 PF01565.18 KXX73112.1 - 3.9e-22 78.2 5.1 1.2e-21 76.6 2.0 2.5 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 KXX73112.1 - 0.00026 20.8 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like NmrA PF05368.8 KXX73113.1 - 3e-34 118.2 0.0 3.8e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX73113.1 - 1e-20 74.4 0.0 1.5e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX73113.1 - 1.7e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX73113.1 - 0.0046 15.7 0.1 0.0064 15.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KXX73113.1 - 0.0072 16.7 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KXX73113.1 - 0.012 15.5 0.9 0.069 13.0 0.6 2.1 1 1 0 1 1 1 0 short chain dehydrogenase PALP PF00291.20 KXX73113.1 - 0.084 12.0 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.13 KXX73113.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 KXX73114.1 - 9.6e-34 116.6 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KXX73115.1 - 3.4e-10 39.4 0.3 8.9e-10 38.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX73115.1 - 9.6e-07 28.3 2.1 9.6e-07 28.3 1.4 2.0 2 0 0 2 2 2 1 F-box domain AIM24 PF01987.12 KXX73117.1 - 2.5e-53 180.7 0.1 3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 FAM176 PF14851.1 KXX73118.1 - 0.00038 20.1 1.1 0.00039 20.1 0.7 1.1 1 0 0 1 1 1 1 FAM176 family DUF2890 PF11081.3 KXX73118.1 - 0.012 15.6 4.2 0.012 15.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 KXX73118.1 - 0.018 14.1 5.9 0.017 14.1 4.1 1.0 1 0 0 1 1 1 0 BUD22 BSP_II PF05432.6 KXX73118.1 - 0.019 14.2 9.4 0.022 14.0 6.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.7 KXX73118.1 - 0.064 12.0 3.1 0.06 12.1 2.1 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein RXT2_N PF08595.6 KXX73118.1 - 0.18 11.5 8.9 0.25 11.1 6.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 KXX73118.1 - 0.33 9.3 11.7 0.38 9.1 8.1 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KXX73118.1 - 0.38 10.0 12.5 0.4 9.9 8.7 1.0 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 KXX73118.1 - 0.71 9.4 10.5 0.85 9.1 7.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 KXX73118.1 - 0.76 10.0 18.1 1.1 9.4 12.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TEX19 PF15553.1 KXX73118.1 - 0.77 9.6 3.2 0.89 9.4 2.2 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 EBV-NA3 PF05009.7 KXX73118.1 - 0.98 8.6 3.0 0.96 8.6 2.1 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Cwf_Cwc_15 PF04889.7 KXX73118.1 - 1.4 8.5 14.3 1.8 8.2 9.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ANAPC15 PF15243.1 KXX73118.1 - 1.8 8.7 15.7 2.2 8.4 10.9 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 KXX73118.1 - 2.1 6.9 20.0 2.6 6.6 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KXX73118.1 - 2.3 7.1 8.6 3 6.7 5.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 KXX73118.1 - 2.3 7.7 8.1 2.9 7.3 5.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Upf2 PF04050.9 KXX73118.1 - 3.2 7.5 13.8 4.2 7.1 9.5 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Tom22 PF04281.8 KXX73118.1 - 5.4 6.5 7.5 7.1 6.1 5.2 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nucleoplasmin PF03066.10 KXX73118.1 - 5.5 6.4 19.9 7.3 6.1 13.8 1.1 1 0 0 1 1 1 0 Nucleoplasmin RRN3 PF05327.6 KXX73118.1 - 5.8 4.8 6.7 6.4 4.7 4.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.7 KXX73118.1 - 7.1 5.7 11.6 9 5.4 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 KXX73118.1 - 9.8 6.1 8.7 13 5.7 6.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HTH_Tnp_Tc5 PF03221.11 KXX73119.1 - 4.3e-10 39.2 0.0 9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KXX73119.1 - 2.3e-05 23.6 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 KXX73119.1 - 0.0039 16.7 0.6 0.0094 15.4 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain PIF1 PF05970.9 KXX73120.1 - 6.8e-59 199.6 0.3 3.2e-46 157.9 0.0 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KXX73120.1 - 5.8e-17 61.9 0.0 1.4e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX73120.1 - 1.3e-07 31.8 0.1 4.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX73120.1 - 3.2e-07 29.9 0.1 8.1e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KXX73120.1 - 6.7e-05 22.9 0.0 0.00044 20.3 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 KXX73120.1 - 0.00011 22.3 0.0 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 KXX73120.1 - 0.00013 19.9 0.2 0.00087 17.1 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 KXX73120.1 - 0.0002 21.4 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KXX73120.1 - 0.001 19.3 0.8 0.0067 16.7 0.0 2.4 1 1 1 2 2 2 1 ABC transporter NACHT PF05729.7 KXX73120.1 - 0.0035 17.0 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 KXX73120.1 - 0.0042 17.2 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KXX73120.1 - 0.0068 16.3 0.0 0.019 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KXX73120.1 - 0.007 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KXX73120.1 - 0.0073 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.1 KXX73120.1 - 0.0084 15.7 3.1 0.082 12.4 0.0 3.2 1 1 2 3 3 3 1 AAA domain PhoH PF02562.11 KXX73120.1 - 0.0097 15.1 0.2 0.029 13.6 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AFG1_ATPase PF03969.11 KXX73120.1 - 0.014 14.2 0.1 0.027 13.2 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase Peptidase_M74 PF03411.8 KXX73120.1 - 0.021 14.0 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Arch_ATPase PF01637.13 KXX73120.1 - 0.024 14.3 0.2 0.067 12.8 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 KXX73120.1 - 0.037 13.4 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KXX73120.1 - 0.037 13.2 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_7 PF12775.2 KXX73120.1 - 0.042 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DUF2075 PF09848.4 KXX73120.1 - 0.043 12.7 0.0 0.089 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KXX73120.1 - 0.046 13.1 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 KXX73120.1 - 0.056 12.3 0.1 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 KXX73120.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 KXX73120.1 - 0.06 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 KXX73120.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 KXX73120.1 - 0.11 12.2 0.4 1.1 8.9 0.1 2.6 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KXX73120.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YjeF_N PF03853.10 KXX73121.1 - 3e-39 134.3 0.0 4.7e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KXX73121.1 - 4.4e-13 49.6 0.2 1.2e-12 48.3 0.2 1.8 1 0 0 1 1 1 1 FDF domain VWA_2 PF13519.1 KXX73121.1 - 0.036 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Abhydrolase_6 PF12697.2 KXX73123.1 - 2.4e-20 73.4 0.2 2.9e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX73123.1 - 2.4e-07 30.6 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX73123.1 - 1.1e-05 25.1 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX73123.1 - 0.0024 17.6 0.0 0.0059 16.4 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 KXX73123.1 - 0.031 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus p450 PF00067.17 KXX73124.1 - 2.1e-41 141.9 0.0 2.7e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KXX73125.1 - 2.3e-11 43.8 0.0 8.2e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73125.1 - 4.2e-06 26.5 0.0 9.2e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX73125.1 - 4.1e-05 23.1 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KXX73125.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KXX73125.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 KXX73125.1 - 0.038 12.9 0.0 0.42 9.5 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein adh_short_C2 PF13561.1 KXX73125.1 - 0.047 13.4 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3425 PF11905.3 KXX73126.1 - 2.4e-21 76.0 2.7 8.1e-21 74.3 1.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Pkinase PF00069.20 KXX73127.1 - 2.5e-25 89.1 0.0 5.1e-25 88.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73127.1 - 1.7e-12 46.9 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KXX73127.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX73127.1 - 0.0019 17.9 0.1 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KXX73127.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_23 PF13489.1 KXX73128.1 - 2.2e-22 79.5 0.0 3.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX73128.1 - 1.1e-13 51.4 0.0 2.5e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX73128.1 - 2.4e-09 36.9 0.0 3.4e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX73128.1 - 7.4e-08 32.9 0.0 1.2e-06 29.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX73128.1 - 2.8e-07 30.9 0.0 2.6e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX73128.1 - 0.00016 20.9 0.0 0.0042 16.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX73128.1 - 0.00029 21.1 0.0 0.00096 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX73128.1 - 0.0046 16.0 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 KXX73128.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KXX73128.1 - 0.014 15.4 0.0 0.066 13.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KXX73128.1 - 0.032 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KXX73128.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KXX73128.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.14 KXX73128.1 - 0.14 12.1 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase CorA PF01544.13 KXX73129.1 - 4.2e-07 29.2 0.4 9.6e-07 28.1 0.2 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein vMSA PF00695.14 KXX73130.1 - 0.68 9.0 4.7 0.91 8.6 3.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PAT1 PF09770.4 KXX73130.1 - 1.3 7.2 5.9 1.5 6.9 4.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_11 PF08241.7 KXX73131.1 - 3.1e-11 43.6 0.0 8.6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX73131.1 - 5e-09 35.6 0.0 8.2e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KXX73131.1 - 1.7e-07 31.6 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX73131.1 - 8.1e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX73131.1 - 3.9e-06 26.8 0.0 6.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX73131.1 - 1.2e-05 25.5 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Se-cys_synth_N PF12390.3 KXX73131.1 - 0.0032 17.5 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Selenocysteine synthase N terminal Methyltransf_23 PF13489.1 KXX73131.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX73131.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ifi-6-16 PF06140.8 KXX73132.1 - 3.1e-05 23.6 27.5 3.1e-05 23.6 19.1 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family Cyclin_N PF00134.18 KXX73133.1 - 9.2e-09 34.9 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spy1 PF11357.3 KXX73133.1 - 0.078 13.0 0.7 6.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein WD40 PF00400.27 KXX73135.1 - 0.007 16.2 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat HET PF06985.6 KXX73136.1 - 1.8e-22 80.0 0.0 4.7e-22 78.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KXX73137.1 - 1.9e-06 27.6 0.1 7.1e-05 22.5 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KXX73137.1 - 0.00019 21.1 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KXX73137.1 - 0.00042 20.4 0.0 0.0031 17.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.2 KXX73137.1 - 0.00062 19.7 0.0 0.0072 16.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KXX73137.1 - 0.00065 19.7 0.0 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 KXX73137.1 - 0.0014 17.9 0.0 0.005 16.1 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KXX73137.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_helicase PF00910.17 KXX73137.1 - 0.0031 17.6 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase PGAP1 PF07819.8 KXX73137.1 - 0.0036 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_17 PF13207.1 KXX73137.1 - 0.012 16.4 0.2 0.073 13.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 KXX73137.1 - 0.02 14.7 0.0 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KXX73137.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KXX73137.1 - 0.035 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 KXX73137.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PPV_E1_C PF00519.12 KXX73137.1 - 0.042 12.4 0.0 0.087 11.4 0.0 1.4 2 0 0 2 2 2 0 Papillomavirus helicase Lipase_3 PF01764.20 KXX73137.1 - 0.063 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Sigma54_activ_2 PF14532.1 KXX73137.1 - 0.13 12.3 0.0 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Pkinase PF00069.20 KXX73138.1 - 9.6e-64 215.0 0.0 1.3e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73138.1 - 1.1e-25 90.1 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX73138.1 - 6.7e-08 31.8 0.0 4.2e-07 29.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KXX73138.1 - 0.00067 19.4 0.3 0.0058 16.3 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX73138.1 - 0.045 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Speriolin_N PF15058.1 KXX73139.1 - 0.013 15.3 3.0 0.28 11.0 2.1 2.0 1 1 0 1 1 1 0 Speriolin N terminus Zn_clus PF00172.13 KXX73140.1 - 1.8e-08 34.1 11.8 2.8e-08 33.5 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX73140.1 - 9e-07 27.8 0.1 1.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.1 KXX73141.1 - 1.1e-25 89.3 16.7 3.8e-15 55.8 0.0 11.6 8 2 6 14 14 14 4 HEAT-like repeat HEAT_2 PF13646.1 KXX73141.1 - 2.5e-23 82.1 1.5 5.4e-07 29.8 0.0 8.1 3 3 6 9 9 9 6 HEAT repeats HEAT PF02985.17 KXX73141.1 - 2.2e-22 77.0 20.7 1.1e-05 25.0 0.0 10.1 13 1 0 13 13 12 5 HEAT repeat MMS19_C PF12460.3 KXX73141.1 - 7.5e-12 44.6 1.7 0.0015 17.3 0.0 5.3 5 1 1 6 6 6 4 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 KXX73141.1 - 2.2e-08 34.3 0.0 0.075 13.4 0.0 6.3 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KXX73141.1 - 8e-06 25.6 1.5 0.00043 20.1 0.3 4.1 2 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KXX73141.1 - 0.00015 21.1 0.3 4.3 6.6 0.0 6.3 7 3 2 9 9 9 1 CLASP N terminal Arm PF00514.18 KXX73141.1 - 0.00072 19.2 5.7 0.11 12.3 0.0 5.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KXX73141.1 - 0.0075 15.9 0.8 6 6.5 0.0 4.5 5 2 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF4303 PF14136.1 KXX73141.1 - 0.026 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) HEAT_PBS PF03130.11 KXX73141.1 - 0.1 13.1 5.4 3 8.5 0.0 5.0 5 0 0 5 5 2 0 PBS lyase HEAT-like repeat Dynamin_N PF00350.18 KXX73142.1 - 1.3e-33 116.2 0.1 2.3e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX73142.1 - 4.1e-15 55.3 0.0 4.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KXX73142.1 - 6.7e-05 22.8 0.0 0.00033 20.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KXX73142.1 - 0.0008 19.2 1.1 0.0026 17.6 0.1 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 KXX73142.1 - 0.002 18.6 0.0 0.006 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KXX73142.1 - 0.018 15.0 0.0 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX73142.1 - 0.046 14.0 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Syntaxin_2 PF14523.1 KXX73142.1 - 0.081 12.9 0.8 2.1 8.4 0.0 3.3 4 0 0 4 4 4 0 Syntaxin-like protein AAA_23 PF13476.1 KXX73142.1 - 0.087 13.1 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KXX73142.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldolase_II PF00596.16 KXX73144.1 - 7.8e-30 103.8 0.0 9.8e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD_binding_3 PF01494.14 KXX73145.1 - 1.2e-14 54.1 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_C PF05199.8 KXX73146.1 - 2.5e-32 112.1 0.0 3.9e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KXX73146.1 - 1.9e-29 102.7 0.0 5.9e-25 88.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX73146.1 - 0.00067 19.6 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX73146.1 - 0.0057 16.5 0.0 0.063 13.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73146.1 - 0.0061 15.4 0.3 0.011 14.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX73146.1 - 0.047 12.5 1.5 0.92 8.3 0.6 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KXX73146.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KXX73146.1 - 0.056 13.4 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PH_8 PF15409.1 KXX73147.1 - 0.033 14.2 0.8 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1232 PF06803.7 KXX73147.1 - 0.32 10.4 6.1 0.09 12.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) ADH_zinc_N PF00107.21 KXX73148.1 - 3.2e-15 55.8 0.1 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX73148.1 - 1.7e-09 38.6 0.0 3.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX73148.1 - 5.6e-06 26.0 0.1 0.011 15.4 0.0 3.1 2 2 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Formyl_trans_N PF00551.14 KXX73149.1 - 2.1e-37 128.3 0.0 2.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 KXX73149.1 - 0.015 14.5 0.1 0.027 13.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) Sas10 PF09368.5 KXX73150.1 - 1e-29 102.5 5.9 1e-29 102.5 4.1 2.8 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KXX73150.1 - 2.4e-13 50.0 1.2 1.2e-12 47.8 0.0 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF3106 PF11304.3 KXX73150.1 - 0.017 15.5 10.2 0.21 12.0 4.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) adh_short PF00106.20 KXX73151.1 - 1e-20 74.3 1.0 1.3e-20 73.9 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73151.1 - 4e-08 33.1 0.4 6.3e-08 32.4 0.1 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX73151.1 - 6e-06 25.9 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KXX73151.1 - 0.00063 19.5 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX73151.1 - 0.0093 15.9 1.3 0.021 14.8 0.6 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KXX73151.1 - 0.092 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain WD40 PF00400.27 KXX73153.1 - 1.8e-27 94.1 0.2 5.9e-14 51.3 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 KXX73153.1 - 1.1e-08 34.8 0.1 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX73153.1 - 7.4e-08 32.5 0.3 1.9e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 KXX73153.1 - 2.6e-07 29.1 2.1 0.002 16.3 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 KAP_NTPase PF07693.9 KXX73153.1 - 0.0032 16.4 0.1 0.0071 15.3 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.17 KXX73153.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Gmad1 PF10647.4 KXX73153.1 - 0.013 14.8 1.8 0.36 10.1 0.2 2.3 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain APS_kinase PF01583.15 KXX73153.1 - 0.023 14.3 0.1 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 KXX73153.1 - 0.028 14.5 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nbas_N PF15492.1 KXX73153.1 - 0.033 13.3 0.0 10 5.1 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AAA_18 PF13238.1 KXX73153.1 - 0.058 13.7 0.0 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KXX73153.1 - 0.072 13.3 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.7 KXX73153.1 - 0.43 10.2 1.5 40 4.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3716 PF12511.3 KXX73154.1 - 1.9e-16 59.4 8.3 3.1e-16 58.6 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AT_hook PF02178.14 KXX73154.1 - 1.1 9.1 4.4 9.1 6.3 0.3 2.5 2 0 0 2 2 2 0 AT hook motif PAT1 PF09770.4 KXX73154.1 - 3.4 5.8 15.3 5.4 5.1 10.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4419 PF14388.1 KXX73155.1 - 4e-62 210.1 0.0 5e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FAD_binding_4 PF01565.18 KXX73156.1 - 2.4e-19 69.2 0.8 5e-19 68.1 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX73156.1 - 9.4e-08 31.8 0.1 2.2e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Erg28 PF03694.8 KXX73157.1 - 1.8e-11 44.0 0.1 2.2e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GST_N PF02798.15 KXX73158.1 - 4.2e-09 36.4 0.0 6.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX73158.1 - 4.8e-08 32.8 0.0 6.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX73158.1 - 2.2e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KXX73158.1 - 4.3e-06 26.6 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX73158.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX73158.1 - 0.00032 21.1 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Gtr1_RagA PF04670.7 KXX73159.1 - 0.15 11.2 0.2 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 KXX73160.1 - 2.4e-18 66.7 0.0 9.3e-16 58.3 0.0 3.2 3 0 0 3 3 2 1 ABC transporter ABC_membrane PF00664.18 KXX73160.1 - 5.6e-08 32.5 12.2 1.3e-07 31.3 3.8 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KXX73160.1 - 5.6e-06 25.7 0.5 0.02 14.1 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 KXX73160.1 - 9.2e-05 21.4 0.0 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KXX73160.1 - 0.0011 19.1 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KXX73160.1 - 0.0021 17.9 0.2 2 8.3 0.2 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KXX73160.1 - 0.0023 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX73160.1 - 0.0075 16.2 0.1 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Herpes_Helicase PF02689.9 KXX73160.1 - 0.0089 13.8 0.0 0.014 13.2 0.0 1.2 1 0 0 1 1 1 1 Helicase UPF0079 PF02367.12 KXX73160.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KXX73160.1 - 0.012 15.5 0.4 0.054 13.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 KXX73160.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KXX73160.1 - 0.023 13.8 0.1 0.066 12.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 KXX73160.1 - 0.038 14.1 0.5 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX73160.1 - 0.076 12.4 0.1 0.2 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 KXX73160.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase UvrD_C_2 PF13538.1 KXX73160.1 - 0.087 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank_2 PF12796.2 KXX73161.1 - 1.8e-16 60.2 0.3 2.5e-09 37.3 0.0 3.3 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73161.1 - 1.7e-10 40.1 0.3 0.00039 20.0 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KXX73161.1 - 2e-10 40.8 0.1 1.1e-05 25.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX73161.1 - 2.5e-07 30.6 0.1 0.00026 21.1 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73161.1 - 4.7e-07 29.4 0.0 0.0097 16.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Rad51 PF08423.6 KXX73162.1 - 5.3e-07 28.8 0.0 2.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 KXX73162.1 - 0.00049 19.2 0.2 0.0011 18.1 0.1 1.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 KXX73162.1 - 0.0025 17.2 1.0 0.37 10.1 0.1 2.6 2 1 0 2 2 2 2 AAA domain RecA PF00154.16 KXX73162.1 - 0.0028 16.7 0.3 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 KXX73162.1 - 0.13 11.1 0.2 5.1 5.9 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain zf-H2C2_2 PF13465.1 KXX73163.1 - 6.4e-10 38.8 15.5 1.5e-06 28.1 2.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KXX73163.1 - 1.6e-07 31.2 14.9 0.0015 18.7 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX73163.1 - 4.8e-05 23.3 12.7 0.0071 16.6 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX73163.1 - 1.1 9.4 4.9 1.5 9.0 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1488 PF07369.6 KXX73164.1 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1488) GWT1 PF06423.7 KXX73165.1 - 6.3e-46 155.8 2.1 1.6e-45 154.5 1.5 1.7 1 0 0 1 1 1 1 GWT1 DUF4492 PF14899.1 KXX73165.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Pkinase PF00069.20 KXX73166.1 - 4.4e-60 203.0 0.0 8.9e-60 202.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73166.1 - 5.2e-33 114.1 0.0 9.8e-28 96.9 0.0 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KXX73166.1 - 2.3e-05 23.4 0.0 0.024 13.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KXX73166.1 - 0.00015 21.5 0.1 0.00075 19.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX73166.1 - 0.0064 15.5 0.1 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KXX73166.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Tuberculin PF12198.3 KXX73167.1 - 7.8 6.4 9.5 13 5.7 0.2 2.3 2 0 0 2 2 2 0 Theoretical tuberculin protein Arrestin_N PF00339.24 KXX73168.1 - 0.00091 19.0 0.0 0.076 12.8 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Abhydrolase_5 PF12695.2 KXX73169.1 - 7.6e-08 32.2 0.1 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KXX73169.1 - 3.5e-07 28.8 0.0 0.003 15.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KXX73169.1 - 0.0011 18.9 1.1 0.002 18.0 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2434 PF10361.4 KXX73170.1 - 5.8e-129 429.3 7.8 7.8e-129 428.9 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) HemY_N PF07219.8 KXX73170.1 - 0.72 9.4 2.8 9.1 5.8 0.1 2.7 2 0 0 2 2 2 0 HemY protein N-terminus COG5 PF10392.4 KXX73171.1 - 1.1e-40 138.6 1.4 1.1e-40 138.6 0.9 1.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 SPX PF03105.14 KXX73171.1 - 0.055 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 SPX domain DUF342 PF03961.8 KXX73171.1 - 0.11 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Esterase PF00756.15 KXX73175.1 - 3.3e-08 33.2 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KXX73175.1 - 0.00014 21.7 0.1 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX73175.1 - 0.00019 20.7 0.1 0.00033 19.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AA_permease_2 PF13520.1 KXX73176.1 - 1.1e-36 126.3 42.2 3.3e-36 124.7 29.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX73176.1 - 4.4e-10 38.4 33.1 7.2e-07 27.9 6.2 2.3 2 0 0 2 2 2 2 Amino acid permease EcsB PF05975.7 KXX73177.1 - 0.019 13.4 0.3 0.026 12.9 0.2 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Choline_transpo PF04515.7 KXX73178.1 - 0.0047 15.7 0.0 0.0057 15.4 0.0 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter PilM PF07419.7 KXX73179.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 PilM zf-C2H2_4 PF13894.1 KXX73181.1 - 0.0068 16.6 0.3 0.0068 16.6 0.2 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger DHC PF09626.5 KXX73181.1 - 0.017 15.7 3.7 0.023 15.3 1.2 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c zf-C2H2 PF00096.21 KXX73181.1 - 0.038 14.3 10.1 0.039 14.3 0.1 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.7 KXX73181.1 - 2.5 6.5 4.9 0.71 8.3 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FA_desaturase PF00487.19 KXX73182.1 - 4.1 6.7 9.8 5.3 6.4 6.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Ank_2 PF12796.2 KXX73183.1 - 1.4e-15 57.3 0.5 4.5e-11 42.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73183.1 - 2.9e-13 48.9 1.3 0.00012 21.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX73183.1 - 2.6e-12 46.5 0.1 1.6e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX73183.1 - 3.7e-10 40.0 0.2 0.003 18.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73183.1 - 8.3e-08 31.7 0.1 0.023 14.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.4 KXX73183.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PNP_UDP_1 PF01048.15 KXX73184.1 - 4e-06 25.9 0.1 1.7e-05 23.8 0.0 1.9 1 1 1 2 2 2 2 Phosphorylase superfamily Sugar_tr PF00083.19 KXX73185.1 - 2.5e-109 365.8 25.0 2.9e-109 365.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX73185.1 - 5.2e-25 87.9 31.6 1.7e-16 59.8 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KXX73185.1 - 0.006 14.6 0.7 0.012 13.6 0.5 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M43 PF05572.8 KXX73186.1 - 3.5e-19 68.9 0.2 4.8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KXX73186.1 - 1.1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX73186.1 - 4e-07 30.1 0.1 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX73186.1 - 1.1e-06 28.8 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KXX73186.1 - 0.0018 17.8 1.1 0.0027 17.2 0.7 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KXX73186.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KXX73186.1 - 0.09 11.6 0.5 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.6 KXX73186.1 - 0.098 12.4 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF1025 PF06262.6 KXX73186.1 - 0.14 12.0 0.4 0.28 10.9 0.3 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Dioxygenase_C PF00775.16 KXX73188.1 - 5e-08 32.4 0.2 1.1e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase Aminotran_5 PF00266.14 KXX73190.1 - 8.4e-14 51.0 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KXX73190.1 - 0.0024 16.8 0.0 0.02 13.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 KXX73190.1 - 0.053 11.9 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) AAL_decarboxy PF03306.8 KXX73192.1 - 1.3e-73 246.7 0.2 1.5e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Ank_2 PF12796.2 KXX73195.1 - 4.7e-34 116.6 0.1 4e-13 49.5 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73195.1 - 3e-25 86.7 3.9 0.00011 21.8 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KXX73195.1 - 7.4e-21 74.1 3.0 1.7e-06 28.4 0.0 5.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73195.1 - 3.8e-18 63.7 2.8 0.043 14.0 0.1 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KXX73195.1 - 6.4e-18 64.3 5.2 9.5e-06 25.6 0.1 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) NPV_P10 PF05531.7 KXX73195.1 - 3.2 8.0 5.4 1.3 9.3 0.1 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_trans PF04082.13 KXX73196.1 - 2.2e-13 49.6 3.7 2.2e-13 49.6 2.5 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KXX73196.1 - 1.6e-08 34.2 8.6 0.0011 19.0 2.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX73196.1 - 1.8e-08 34.2 7.3 0.0026 17.9 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX73196.1 - 3.9e-06 26.8 12.8 7.6e-05 22.8 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX73196.1 - 0.05 13.7 0.7 0.61 10.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KXX73196.1 - 0.2 11.1 0.1 0.39 10.1 0.1 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain VHS PF00790.14 KXX73197.1 - 1.6e-38 131.4 0.2 3.8e-38 130.3 0.2 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KXX73197.1 - 2.4e-16 59.0 0.2 4.3e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX73197.1 - 1.3e-15 56.4 0.1 2.7e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX73197.1 - 1.4e-15 56.4 0.0 2.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KXX73197.1 - 0.021 14.7 1.6 0.087 12.8 1.1 2.0 1 0 0 1 1 1 0 GAT domain TIR PF01582.15 KXX73197.1 - 0.079 12.4 0.3 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 TIR domain UIM PF02809.15 KXX73197.1 - 0.13 11.9 5.6 0.34 10.6 3.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Macoilin PF09726.4 KXX73197.1 - 0.14 10.4 3.4 0.32 9.2 2.4 1.5 1 0 0 1 1 1 0 Transmembrane protein Pectate_lyase_3 PF12708.2 KXX73198.1 - 7.2e-83 278.1 14.7 2.4e-68 230.6 3.3 3.2 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KXX73198.1 - 5.5e-05 22.5 1.1 0.015 14.7 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PhyH PF05721.8 KXX73199.1 - 9.2e-11 42.1 0.0 3.4e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) SET PF00856.23 KXX73200.1 - 1.1e-19 71.3 1.0 1.1e-19 71.3 0.7 2.6 2 2 0 2 2 2 1 SET domain zf-DHHC PF01529.15 KXX73201.1 - 7e-28 97.1 0.1 7e-28 97.1 0.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PBP1_TM PF14812.1 KXX73202.1 - 0.013 15.8 0.9 0.02 15.2 0.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 KXX73202.1 - 0.041 12.6 1.9 0.049 12.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3245 PF11595.3 KXX73202.1 - 0.085 13.1 1.7 0.11 12.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Nucleoplasmin PF03066.10 KXX73202.1 - 0.088 12.3 0.3 0.1 12.1 0.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 KXX73202.1 - 0.14 11.4 3.0 0.17 11.1 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein Bd3614_N PF14442.1 KXX73202.1 - 0.32 10.9 3.5 0.42 10.5 2.5 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF2423 PF10338.4 KXX73203.1 - 5.9e-05 22.9 1.8 5.9e-05 22.9 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) SPOUT_MTase PF02590.12 KXX73203.1 - 0.024 14.3 0.2 0.025 14.2 0.1 1.0 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Phosphodiest PF01663.17 KXX73204.1 - 1.5e-17 64.0 1.7 1.2e-16 61.0 1.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX73204.1 - 6e-06 25.6 0.0 0.00034 19.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.13 KXX73204.1 - 4.5e-05 22.9 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF883 PF05957.8 KXX73204.1 - 0.29 11.5 3.0 3 8.2 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PINIT PF14324.1 KXX73205.1 - 4.4e-41 140.3 0.0 7.1e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KXX73205.1 - 1.3e-21 75.8 6.5 2.2e-21 75.0 4.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KXX73205.1 - 4.2e-07 29.3 0.0 9.2e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 KXX73205.1 - 1.5e-06 27.6 2.1 2.9e-06 26.7 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 KXX73205.1 - 0.011 15.3 0.1 0.011 15.3 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_5 PF14634.1 KXX73205.1 - 0.2 11.3 4.1 0.39 10.4 2.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX73205.1 - 0.22 11.4 5.7 0.4 10.5 4.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KXX73205.1 - 0.36 10.6 5.3 0.63 9.9 3.7 1.4 1 0 0 1 1 1 0 Ring finger domain TRAPP PF04051.11 KXX73206.1 - 7.6e-46 155.3 0.0 9e-46 155.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Gly-zipper_OmpA PF13436.1 KXX73206.1 - 6.8 6.3 13.3 14 5.3 9.2 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Ribosomal_L28e PF01778.12 KXX73207.1 - 1.5e-36 125.3 0.2 2e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family FA_hydroxylase PF04116.8 KXX73208.1 - 2.2e-15 57.0 24.3 6.4e-15 55.5 13.9 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Ldh_1_C PF02866.13 KXX73209.1 - 9.1e-44 149.2 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KXX73209.1 - 9.4e-44 148.6 0.1 1.4e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KXX73209.1 - 0.0019 16.9 0.0 0.0037 16.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 KXX73209.1 - 0.14 11.4 0.1 8.8 5.6 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase DUF2015 PF09435.5 KXX73210.1 - 5.8e-46 155.4 0.0 6.4e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) PCI PF01399.22 KXX73211.1 - 1.6e-20 73.3 0.0 4.8e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KXX73211.1 - 0.00041 19.7 0.5 0.042 13.1 0.0 2.5 2 0 0 2 2 2 2 Putative aspartate racemase Phage_Nu1 PF07471.7 KXX73211.1 - 0.2 11.1 4.1 0.21 11.0 1.0 2.3 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 eIF-5a PF01287.15 KXX73212.1 - 4.8e-06 26.4 0.1 9.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FbpA PF05833.6 KXX73213.1 - 4.7e-38 130.9 7.8 4.7e-38 130.9 5.4 2.2 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KXX73213.1 - 4.9e-37 125.9 1.2 1.4e-36 124.5 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KXX73213.1 - 8.9e-24 83.2 0.0 2.1e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Methyltransf_23 PF13489.1 KXX73214.1 - 0.00079 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX73214.1 - 0.036 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KXX73214.1 - 0.064 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NACHT PF05729.7 KXX73215.1 - 5.4e-11 42.4 0.1 1.5e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX73215.1 - 1.3e-07 31.8 0.2 1.3e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KXX73215.1 - 2.4e-06 26.5 0.0 4.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KXX73215.1 - 0.0025 17.9 0.2 0.31 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KXX73215.1 - 0.014 14.4 0.1 0.034 13.1 0.0 1.6 1 1 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.15 KXX73215.1 - 0.063 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KXX73215.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KXX73216.1 - 1.5e-67 221.2 14.8 4.7e-09 35.7 0.0 11.6 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KXX73216.1 - 2.9e-45 153.3 0.2 4.6e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KXX73216.1 - 4.2e-08 31.7 2.5 0.0027 15.9 0.0 5.0 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX73216.1 - 9.7e-05 21.2 5.6 1.2 7.8 0.0 4.7 4 2 0 4 4 4 3 Nup133 N terminal like UCH PF00443.24 KXX73217.1 - 1.6e-21 76.6 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KXX73217.1 - 1.1e-11 44.7 0.1 2.3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein CENP-S PF15630.1 KXX73218.1 - 1.9e-33 114.4 0.2 4.6e-33 113.2 0.0 1.6 1 1 1 2 2 2 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KXX73218.1 - 0.0056 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KXX73218.1 - 0.015 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 KXX73218.1 - 0.051 13.3 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KXX73218.1 - 0.064 13.3 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 MTHFR PF02219.12 KXX73220.1 - 5.3e-101 337.4 0.0 8.2e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.13 KXX73221.1 - 1.2e-51 174.5 0.0 2.2e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BNIP3 PF06553.7 KXX73222.1 - 0.77 9.1 3.2 1.2 8.4 2.2 1.2 1 0 0 1 1 1 0 BNIP3 PAT1 PF09770.4 KXX73222.1 - 9.8 4.2 11.2 11 4.0 7.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HLH PF00010.21 KXX73223.1 - 4e-11 42.4 0.1 4e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3237 PF11578.3 KXX73224.1 - 8.6e-36 122.4 0.0 1.4e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KXX73224.1 - 2.8e-06 26.9 5.9 0.013 15.2 0.5 2.3 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 KXX73224.1 - 0.053 13.6 4.7 2.2 8.4 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 KXX73224.1 - 0.07 13.1 0.4 0.2 11.7 0.2 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein MFS_1 PF07690.11 KXX73225.1 - 2.6e-40 138.2 33.1 2.6e-40 138.2 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX73225.1 - 2.5e-07 29.2 2.9 3.6e-07 28.7 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 KXX73225.1 - 0.0054 16.4 1.1 0.024 14.3 0.7 2.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) Dispanin PF04505.7 KXX73225.1 - 0.021 14.3 0.4 0.24 10.9 0.0 2.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein GP41 PF00517.12 KXX73225.1 - 5.1 6.6 0.0 5.1 6.6 0.0 2.5 3 0 0 3 3 3 0 Retroviral envelope protein DUF3632 PF12311.3 KXX73226.1 - 1.4e-40 139.1 1.2 1.4e-40 139.1 0.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 KXX73227.1 - 2.9e-17 62.5 0.0 4.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_47 PF01532.15 KXX73228.1 - 3.1e-149 497.4 0.0 3.7e-149 497.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Helicase_C PF00271.26 KXX73229.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KXX73229.1 - 1.9e-05 23.6 0.0 0.00011 21.1 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Glyco_hydro_7 PF00840.15 KXX73231.1 - 1.3e-161 537.8 5.2 1.5e-161 537.6 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Beach PF02138.13 KXX73232.1 - 9.6e-108 359.7 0.0 1.7e-107 358.8 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KXX73232.1 - 8e-12 44.9 0.9 2.9e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KXX73232.1 - 2.2e-11 44.2 0.0 5.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KXX73232.1 - 8.7e-07 28.5 1.2 0.066 13.1 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DDOST_48kD PF03345.9 KXX73234.1 - 1.5e-166 554.1 0.0 1.7e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Peptidase_S8 PF00082.17 KXX73235.1 - 1.2e-52 178.8 10.1 1.8e-52 178.2 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KXX73235.1 - 7e-22 77.7 0.4 1.5e-21 76.7 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PPR_2 PF13041.1 KXX73236.1 - 0.0036 17.2 0.0 0.27 11.2 0.0 3.4 3 1 1 4 4 4 2 PPR repeat family PPR PF01535.15 KXX73236.1 - 0.029 14.3 0.1 10 6.3 0.0 2.9 2 0 0 2 2 2 0 PPR repeat PP2C PF00481.16 KXX73237.1 - 5.4e-84 281.5 0.0 8.3e-84 280.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KXX73237.1 - 0.0033 16.8 0.3 0.0074 15.7 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.7 KXX73238.1 - 1.7e-12 47.1 7.7 0.00023 21.0 0.2 4.6 5 0 0 5 5 5 3 Putative Ig domain DUF4448 PF14610.1 KXX73238.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mso1_Sec1_bdg PF14475.1 KXX73238.1 - 1.1 8.7 3.0 5.1 6.5 0.2 3.2 3 0 0 3 3 3 0 Sec1-binding region of Mso1 Methyltransf_16 PF10294.4 KXX73239.1 - 5.2e-45 153.0 0.0 6.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KXX73239.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DPBB_1 PF03330.13 KXX73240.1 - 0.097 12.6 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1712 PF08217.6 KXX73241.1 - 1.6e-10 39.9 0.0 1.3e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) HET PF06985.6 KXX73242.1 - 6.5e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP70 PF00012.15 KXX73243.1 - 5.5e-09 34.4 0.1 2e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.20 KXX73243.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family MreB_Mbl PF06723.8 KXX73243.1 - 0.074 11.6 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein MAD PF05557.8 KXX73245.1 - 0.0052 14.9 13.3 0.0075 14.4 9.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Tropomyosin_1 PF12718.2 KXX73245.1 - 0.023 14.5 10.1 0.059 13.2 7.0 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF724 PF05266.9 KXX73245.1 - 0.025 14.1 6.5 0.049 13.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Reo_sigmaC PF04582.7 KXX73245.1 - 0.033 13.3 0.6 0.043 12.9 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.1 KXX73245.1 - 0.06 12.5 9.0 0.11 11.7 6.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.14 KXX73245.1 - 0.091 10.6 5.1 0.11 10.3 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 KXX73245.1 - 0.14 11.9 17.9 0.87 9.4 4.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.4 KXX73245.1 - 0.16 11.6 0.8 0.32 10.6 0.6 1.5 1 0 0 1 1 1 0 Apolipoprotein O Kinesin-relat_1 PF12711.2 KXX73245.1 - 0.25 11.7 8.1 0.051 13.9 1.8 2.4 1 1 1 2 2 2 0 Kinesin motor Macoilin PF09726.4 KXX73245.1 - 0.47 8.6 8.4 0.62 8.2 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein MscS_porin PF12795.2 KXX73245.1 - 0.67 9.2 21.5 1.2 8.4 14.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Vps53_N PF04100.7 KXX73245.1 - 0.71 8.5 8.6 1.5 7.5 5.9 1.6 1 1 0 1 1 1 0 Vps53-like, N-terminal AAA_13 PF13166.1 KXX73245.1 - 0.96 7.8 13.1 0.29 9.5 1.7 2.0 1 1 1 2 2 2 0 AAA domain Sec5 PF15469.1 KXX73245.1 - 1.2 8.8 7.1 4.5 6.9 0.2 2.5 1 1 1 2 2 2 0 Exocyst complex component Sec5 Laminin_II PF06009.7 KXX73245.1 - 1.3 8.7 12.0 10 5.9 7.0 2.4 2 1 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KXX73245.1 - 1.7 7.2 12.2 2.9 6.4 8.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KXX73245.1 - 1.8 8.1 17.9 4.1 6.9 12.4 1.6 1 1 0 1 1 1 0 IncA protein DUF3584 PF12128.3 KXX73245.1 - 2.1 5.5 20.7 2 5.6 13.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) COG5 PF10392.4 KXX73245.1 - 2.1 8.3 9.6 1.5 8.8 5.2 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 GAS PF13851.1 KXX73245.1 - 2.8 7.0 15.1 3.7 6.6 10.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 KXX73245.1 - 2.8 7.9 4.7 25 4.8 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KXX73245.1 - 3.8 7.8 11.7 1.2 9.4 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) BRE1 PF08647.6 KXX73245.1 - 5 7.1 14.0 3.2 7.8 7.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.1 KXX73245.1 - 5.3 5.9 10.5 7.7 5.3 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.1 KXX73245.1 - 5.5 6.9 18.5 19 5.2 12.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.3 KXX73245.1 - 7.7 6.4 22.1 0.78 9.6 8.8 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding Pec_lyase_C PF00544.14 KXX73246.1 - 8e-30 103.8 7.4 2e-29 102.5 5.1 1.7 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KXX73246.1 - 0.0015 18.3 18.5 0.087 12.5 1.5 2.5 1 1 1 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.2 KXX73246.1 - 0.097 12.7 6.4 0.19 11.7 4.4 1.5 1 0 0 1 1 1 0 Pectate lyase superfamily protein AKAP2_C PF15304.1 KXX73248.1 - 0.0017 18.0 1.8 0.0017 18.0 1.2 3.1 2 1 0 3 3 3 1 A-kinase anchor protein 2 C-terminus DUF4140 PF13600.1 KXX73248.1 - 8 6.9 8.5 2.8 8.4 1.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.11 KXX73249.1 - 1.7e-21 76.3 28.7 1.7e-21 76.3 19.9 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily NUDIX PF00293.23 KXX73250.1 - 2.5e-17 62.7 0.0 4.1e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KXX73251.1 - 9.2e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.15 KXX73253.1 - 7.3e-19 68.2 0.0 1e-16 61.2 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX73253.1 - 2.3e-12 47.3 6.7 2.4e-11 43.9 4.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KXX73253.1 - 0.00092 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase GMC_oxred_N PF00732.14 KXX73255.1 - 7.1e-67 225.6 0.0 8.8e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73255.1 - 9.4e-37 126.5 0.0 1.7e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX73255.1 - 9.5e-09 34.5 0.1 0.0011 17.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX73255.1 - 8.3e-08 31.5 0.2 0.00045 19.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX73255.1 - 2.5e-05 24.1 0.1 5.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain XPC-binding PF09280.6 KXX73255.1 - 0.0005 19.4 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 XPC-binding domain Pyr_redox_3 PF13738.1 KXX73255.1 - 0.001 19.1 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX73255.1 - 0.0025 16.8 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX73255.1 - 0.015 15.2 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX73255.1 - 0.022 13.2 0.2 0.042 12.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KXX73255.1 - 0.038 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KXX73255.1 - 0.073 12.8 0.5 0.3 10.8 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX73255.1 - 0.084 11.7 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KXX73255.1 - 0.14 12.5 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_2 PF02230.11 KXX73257.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KXX73257.1 - 0.0007 19.1 0.2 0.0051 16.2 0.1 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KXX73257.1 - 0.044 13.0 0.2 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX73257.1 - 0.049 13.3 0.1 0.093 12.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 KXX73258.1 - 2e-30 105.7 5.8 2.3e-30 105.6 4.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 KXX73259.1 - 5.6e-52 176.8 12.0 5.6e-52 176.8 8.3 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX73259.1 - 1.3e-08 33.9 28.7 3.7e-08 32.4 19.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TPR_19 PF14559.1 KXX73259.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1_like PF12832.2 KXX73259.1 - 4.1 7.2 11.3 0.064 13.0 2.3 2.1 2 0 0 2 2 2 0 MFS_1 like family Erg28 PF03694.8 KXX73261.1 - 1.8e-11 44.0 0.1 2.2e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.20 KXX73262.1 - 4.6e-14 52.6 1.3 4.5e-13 49.4 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX73262.1 - 1.4e-06 28.1 0.2 5.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KXX73262.1 - 0.022 14.5 0.0 0.43 10.2 0.0 2.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KXX73263.1 - 3e-39 134.8 0.0 4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-DHHC PF01529.15 KXX73265.1 - 8.8 5.6 6.8 1.9e+02 1.3 4.7 2.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Metallophos_2 PF12850.2 KXX73266.1 - 2.1e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX73266.1 - 0.00014 21.2 4.6 0.00055 19.3 3.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EMP70 PF02990.11 KXX73267.1 - 1.1e-162 542.1 0.2 4.5e-162 540.1 0.1 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Peptidase_S9 PF00326.16 KXX73269.1 - 1.7e-53 181.0 0.0 4.3e-53 179.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX73269.1 - 1.8e-10 40.7 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX73269.1 - 1.4e-07 31.6 0.1 3.1e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KXX73269.1 - 0.062 11.7 0.0 1 7.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) NuA4 PF09340.5 KXX73270.1 - 4.4e-22 77.5 0.0 7.3e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 PspB PF06667.7 KXX73270.1 - 0.19 11.7 0.2 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 Phage shock protein B E1-E2_ATPase PF00122.15 KXX73271.1 - 2.6e-73 245.8 0.0 4.5e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX73271.1 - 6.4e-44 149.6 0.2 6.4e-44 149.6 0.1 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX73271.1 - 1.2e-29 104.2 0.0 1.1e-28 101.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX73271.1 - 2.6e-20 71.6 0.0 5.2e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KXX73271.1 - 2.5e-13 49.7 0.0 4.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX73271.1 - 8.2e-13 48.9 0.1 2.8e-12 47.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX73271.1 - 1.2e-05 25.0 2.0 2.1e-05 24.2 1.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 KXX73272.1 - 2.5e-35 120.7 0.0 4.9e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KXX73272.1 - 3.9e-08 32.3 0.7 6.9e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KXX73272.1 - 0.0044 16.6 2.0 0.032 13.7 0.0 2.5 3 0 0 3 3 3 1 ScpA/B protein Methyltransf_23 PF13489.1 KXX73273.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain GMC_oxred_N PF00732.14 KXX73275.1 - 7.3e-45 153.3 0.0 1.8e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73275.1 - 1.4e-24 87.0 0.0 2.3e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX73275.1 - 0.0017 17.3 0.3 0.75 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX73275.1 - 0.0059 16.5 0.4 3.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73275.1 - 0.04 12.7 0.6 2.4 6.9 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain Autoind_bind PF03472.10 KXX73275.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain GMC_oxred_N PF00732.14 KXX73276.1 - 7.3e-45 153.3 0.0 1.8e-44 152.1 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73276.1 - 1.4e-24 87.0 0.0 2.3e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX73276.1 - 0.0017 17.3 0.3 0.75 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX73276.1 - 0.0059 16.5 0.4 3.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73276.1 - 0.04 12.7 0.6 2.4 6.9 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain Autoind_bind PF03472.10 KXX73276.1 - 0.097 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain HET PF06985.6 KXX73279.1 - 5.1e-23 81.7 0.4 9.9e-22 77.5 0.0 2.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) PAT1 PF09770.4 KXX73281.1 - 4.5 5.3 11.8 5.8 5.0 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nup88 PF10168.4 KXX73282.1 - 0.00032 18.7 2.7 0.42 8.3 0.0 2.9 2 1 0 2 2 2 2 Nuclear pore component Herpes_U30 PF04523.8 KXX73282.1 - 0.019 12.4 0.2 0.026 11.9 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FliT PF05400.8 KXX73282.1 - 0.041 14.3 0.3 0.041 14.3 0.2 2.9 3 0 0 3 3 3 0 Flagellar protein FliT DUF4201 PF13870.1 KXX73282.1 - 0.41 10.0 3.5 0.63 9.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 KXX73282.1 - 0.42 10.1 5.1 0.81 9.2 3.6 1.5 1 0 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 KXX73282.1 - 3.8 7.6 6.2 2.3e+02 1.9 4.3 2.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor SlyX PF04102.7 KXX73282.1 - 4.4 7.7 5.5 3 8.2 0.1 2.9 3 0 0 3 3 3 0 SlyX Sedlin_N PF04628.8 KXX73283.1 - 1.7e-44 150.8 0.0 1.9e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KXX73283.1 - 2e-05 24.3 0.0 0.00043 20.0 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Histone PF00125.19 KXX73284.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KXX73284.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KXX73284.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KXX73284.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KXX73284.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KXX73284.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRM_1 PF00076.17 KXX73285.1 - 5e-16 58.0 0.0 7.1e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX73285.1 - 2.7e-12 46.4 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX73285.1 - 7.5e-09 35.3 0.1 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.4 KXX73286.1 - 5.3e-47 158.1 1.9 5.9e-47 157.9 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRT_C PF08372.5 KXX73286.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF3605 PF12239.3 KXX73287.1 - 1.4e-56 190.7 0.0 1.7e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TPR_11 PF13414.1 KXX73288.1 - 2.8e-41 139.0 24.6 4.2e-13 48.7 4.4 7.3 5 2 2 7 7 7 7 TPR repeat TPR_2 PF07719.12 KXX73288.1 - 1.4e-35 118.3 30.5 5.7e-06 25.8 0.1 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 KXX73288.1 - 2.9e-34 115.2 19.6 1e-07 31.2 0.0 9.5 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KXX73288.1 - 1.3e-32 111.7 22.3 5.8e-23 80.8 0.0 4.8 4 1 2 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KXX73288.1 - 3.5e-30 103.7 23.1 3.9e-09 36.3 0.1 7.6 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 KXX73288.1 - 4e-25 87.9 15.5 7.9e-09 35.7 2.2 7.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KXX73288.1 - 1.1e-23 81.1 3.8 0.00048 19.7 0.2 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 KXX73288.1 - 2.4e-22 79.0 30.4 1.7e-06 28.5 0.8 8.1 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73288.1 - 2.7e-22 77.2 17.7 0.046 14.3 0.1 10.4 5 1 5 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73288.1 - 6.8e-22 75.8 12.5 0.0025 17.8 0.4 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73288.1 - 2.4e-17 61.2 12.4 0.0015 18.1 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 KXX73288.1 - 7.5e-12 44.8 14.2 0.14 12.6 0.4 9.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KXX73288.1 - 3.6e-06 26.7 9.2 0.96 9.3 0.2 4.9 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_15 PF13429.1 KXX73288.1 - 0.0007 18.7 12.2 0.22 10.5 3.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.4 KXX73288.1 - 0.0019 17.7 2.7 4.3 6.7 2.2 3.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) APP_E2 PF12925.2 KXX73288.1 - 0.073 12.6 3.3 5.3 6.5 0.0 3.0 2 1 0 3 3 2 0 E2 domain of amyloid precursor protein TPR_20 PF14561.1 KXX73288.1 - 0.11 12.5 4.4 1.5 8.9 0.9 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX73288.1 - 0.14 12.6 7.4 3.4 8.3 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 KXX73288.1 - 0.4 9.3 7.4 4.6 5.8 0.0 3.0 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KXX73288.1 - 1.1 9.3 12.1 4.8 7.2 0.0 5.7 5 1 1 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX73288.1 - 4.8 7.1 8.7 23 4.9 0.0 4.8 5 1 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF788 PF05620.6 KXX73289.1 - 1.9e-44 151.5 0.0 2.1e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF2955 PF11168.3 KXX73289.1 - 0.01 15.5 0.3 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) FA_desaturase PF00487.19 KXX73289.1 - 0.043 13.2 4.6 0.055 12.9 3.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase LcnG-beta PF11632.3 KXX73289.1 - 0.13 12.0 3.1 0.24 11.1 2.2 1.5 1 0 0 1 1 1 0 Lactococcin G-beta DUF1469 PF07332.6 KXX73289.1 - 0.22 11.2 2.6 0.36 10.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) TRAPPC10 PF12584.3 KXX73290.1 - 4.9e-23 81.2 0.0 8.7e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KXX73290.1 - 0.061 12.7 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 M20_dimer PF07687.9 KXX73291.1 - 2.3e-20 72.4 0.4 5.3e-20 71.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KXX73291.1 - 2.9e-18 66.0 0.0 8.9e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 IF-2B PF01008.12 KXX73292.1 - 3.3e-74 249.3 0.2 3.9e-74 249.1 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.20 KXX73293.1 - 1.7e-12 47.5 1.1 2.8e-12 46.8 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73293.1 - 2.5e-06 27.2 0.6 4.6e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX73293.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Prenyltrans PF00432.16 KXX73294.1 - 5.2e-36 121.8 16.8 2.4e-11 42.9 0.1 6.8 8 0 0 8 8 8 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KXX73294.1 - 1e-21 77.4 0.1 3.8e-15 56.2 0.0 3.9 2 2 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KXX73294.1 - 7.4e-09 35.5 0.0 0.0018 18.2 0.0 3.5 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 KXX73294.1 - 0.15 11.2 0.0 28 3.8 0.0 3.0 2 1 0 3 3 3 0 A-macroglobulin complement component FAD_binding_4 PF01565.18 KXX73295.1 - 3.1e-27 94.7 0.7 5.4e-27 93.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX73295.1 - 0.002 17.9 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.6 KXX73296.1 - 5.8e-08 32.1 0.1 1e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Cupin domain ATPase_gene1 PF09527.5 KXX73296.1 - 0.19 11.5 0.2 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) APC10 PF03256.11 KXX73297.1 - 3e-45 154.2 0.0 4.2e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.8 KXX73297.1 - 0.011 15.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 PITH domain UBX PF00789.15 KXX73297.1 - 0.037 14.0 0.0 4.9 7.2 0.0 2.8 2 1 0 2 2 2 0 UBX domain F5_F8_type_C PF00754.20 KXX73297.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain CTP_transf_2 PF01467.21 KXX73298.1 - 0.017 15.1 0.2 0.048 13.7 0.0 1.8 2 1 0 2 2 2 0 Cytidylyltransferase Peptidase_S28 PF05577.7 KXX73299.1 - 0.098 11.2 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase S28 2OG-FeII_Oxy_3 PF13640.1 KXX73300.1 - 0.0046 17.4 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KXX73300.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KXX73301.1 - 8.9e-05 21.4 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioredoxin_6 PF13848.1 KXX73302.1 - 7.6e-22 78.0 0.1 2e-19 70.1 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KXX73302.1 - 4.2e-06 26.3 0.0 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin T2SE_Nter PF05157.10 KXX73302.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Mre11_DNA_bind PF04152.9 KXX73303.1 - 2.8e-58 196.6 0.2 5.8e-58 195.6 0.1 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KXX73303.1 - 2.1e-26 92.5 0.9 3.1e-26 92.0 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KXX73303.1 - 6.6e-06 26.0 0.1 1.8e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIID_30kDa PF03540.8 KXX73304.1 - 3e-26 90.9 0.3 4.4e-26 90.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Sugar_tr PF00083.19 KXX73305.1 - 1.7e-34 119.2 26.6 9.1e-28 97.0 7.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX73305.1 - 2.9e-08 32.8 23.6 2.9e-08 32.8 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_67N PF03648.9 KXX73307.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus adh_short PF00106.20 KXX73308.1 - 2.3e-09 37.3 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73308.1 - 0.00023 20.8 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3842 PF12953.2 KXX73308.1 - 0.031 14.4 0.2 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Semialdhyde_dh PF01118.19 KXX73308.1 - 0.032 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KXX73308.1 - 0.065 13.3 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peripla_BP_6 PF13458.1 KXX73308.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein EII-Sor PF03609.9 KXX73309.1 - 0.038 13.2 7.1 0.06 12.6 1.9 2.2 1 1 1 2 2 2 0 PTS system sorbose-specific iic component Abhydrolase_6 PF12697.2 KXX73310.1 - 7.5e-16 58.7 0.0 1.3e-15 57.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX73310.1 - 1.1e-05 25.1 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX73310.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 KXX73310.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Aldedh PF00171.17 KXX73311.1 - 8.7e-146 485.8 0.0 1.1e-145 485.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PI-PLC-X PF00388.14 KXX73312.1 - 3e-47 159.6 0.0 4.4e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KXX73312.1 - 2.4e-30 104.9 0.0 4.1e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain TFIIE-A_C-term PF11521.3 KXX73312.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Med19 PF10278.4 KXX73312.1 - 1.4 8.5 5.3 1.9 8.1 0.0 2.6 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 Homeobox_KN PF05920.6 KXX73315.1 - 4.1e-19 67.9 0.2 8.1e-19 67.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KXX73315.1 - 3.7e-08 32.8 0.7 1.2e-07 31.1 0.5 1.9 1 0 0 1 1 1 1 Homeobox domain SKG6 PF08693.5 KXX73316.1 - 1.2e-06 27.7 2.7 1.2e-06 27.7 1.9 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.8 KXX73316.1 - 0.0089 16.3 7.4 0.015 15.6 5.1 1.3 1 0 0 1 1 1 1 Alphavirus glycoprotein J TMEM154 PF15102.1 KXX73316.1 - 0.033 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF2029 PF09594.5 KXX73316.1 - 0.088 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Phospholip_A2_3 PF09056.6 KXX73317.1 - 8.6e-45 151.5 0.2 1.2e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Fringe PF02434.11 KXX73318.1 - 2.2e-07 30.3 0.0 3.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KXX73318.1 - 0.00055 19.5 1.5 0.0011 18.5 1.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KXX73318.1 - 0.014 15.1 0.6 0.028 14.1 0.4 1.4 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.6 KXX73318.1 - 0.036 13.9 0.6 0.081 12.7 0.4 1.5 1 0 0 1 1 1 0 PAN-like domain Cu-oxidase_2 PF07731.9 KXX73319.1 - 2.8e-26 91.6 3.4 6.2e-24 84.0 1.4 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KXX73319.1 - 1.8e-22 79.3 1.0 4.5e-22 78.0 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KXX73319.1 - 0.00013 21.8 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase TPR_11 PF13414.1 KXX73320.1 - 5.2e-10 38.8 13.8 1.1e-07 31.3 0.3 5.8 6 1 0 6 6 6 2 TPR repeat TPR_1 PF00515.23 KXX73320.1 - 1e-07 31.2 9.1 4.6e-05 22.8 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX73320.1 - 1.6e-05 24.4 17.3 0.0006 19.5 0.0 7.5 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73320.1 - 1.6e-05 24.2 0.5 0.51 10.2 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73320.1 - 3e-05 24.2 13.0 2.8 8.8 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX73320.1 - 0.0015 18.4 13.3 0.15 11.9 0.0 5.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX73320.1 - 0.0019 17.8 0.8 0.55 10.1 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX73320.1 - 0.22 12.2 22.7 0.99 10.1 0.0 7.1 6 2 3 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 KXX73320.1 - 0.22 11.6 5.2 2.7 8.1 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KXX73320.1 - 0.25 11.8 6.0 41 4.9 0.0 5.8 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73320.1 - 4 7.8 8.1 1.8e+02 2.6 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat RTA1 PF04479.8 KXX73321.1 - 5.2e-11 42.4 1.2 4.2e-06 26.4 0.1 2.0 2 0 0 2 2 2 2 RTA1 like protein DUF805 PF05656.9 KXX73321.1 - 0.058 13.2 1.6 0.1 12.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) P12 PF12669.2 KXX73321.1 - 7.6 6.8 16.4 1.4 9.1 5.9 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family Glyco_hydro_3 PF00933.16 KXX73322.1 - 1.5e-91 306.4 0.0 2.2e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX73322.1 - 7e-51 172.9 0.0 1.6e-49 168.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX73322.1 - 2.1e-20 72.4 0.1 3.8e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_M48 PF01435.13 KXX73323.1 - 2.1e-49 168.1 0.1 3.2e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KXX73323.1 - 0.0024 16.8 0.7 0.005 15.8 0.5 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF2592 PF10766.4 KXX73323.1 - 0.075 12.3 0.2 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) DUF955 PF06114.8 KXX73323.1 - 0.11 12.2 0.3 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF955) SprT-like PF10263.4 KXX73323.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.1 KXX73323.1 - 0.18 11.1 1.1 0.42 9.9 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) PGA2 PF07543.7 KXX73324.1 - 6.6e-40 136.1 3.2 7.8e-40 135.9 2.2 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 WD40 PF00400.27 KXX73324.1 - 5.6e-07 29.1 1.2 0.0019 17.9 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 KXX73324.1 - 0.0052 14.9 0.1 0.0064 14.6 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SLY PF12485.3 KXX73324.1 - 0.075 13.2 2.3 0.11 12.6 1.6 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF3886 PF13025.1 KXX73324.1 - 3.3 7.7 17.7 25 4.9 0.6 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3886) PPTA PF01239.17 KXX73325.1 - 3.2e-41 136.9 12.8 8.7e-08 31.1 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 KXX73325.1 - 0.039 13.7 0.7 0.49 10.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.16 KXX73325.1 - 2.6 6.8 9.2 1.1 8.0 4.8 1.5 2 0 0 2 2 2 0 Amidase MGC-24 PF05283.6 KXX73325.1 - 6.2 6.5 8.9 11 5.7 6.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) GHMP_kinases_N PF00288.21 KXX73326.1 - 9.7e-19 67.2 0.0 1.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KXX73326.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_6 PF01418.12 KXX73326.1 - 0.0022 17.6 0.0 0.059 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family GalKase_gal_bdg PF10509.4 KXX73326.1 - 0.0041 16.3 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature ABM PF03992.11 KXX73327.1 - 2.3e-05 24.3 3.9 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Ribosomal_L34 PF00468.12 KXX73328.1 - 4e-12 45.6 12.0 6.8e-12 44.8 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_L38e PF01781.13 KXX73329.1 - 4.1e-34 116.1 4.5 4.9e-34 115.8 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family HALZ PF02183.13 KXX73331.1 - 0.0017 17.9 9.6 0.021 14.5 1.2 2.6 2 1 1 3 3 3 2 Homeobox associated leucine zipper Rootletin PF15035.1 KXX73331.1 - 0.0023 17.9 1.9 0.0034 17.3 1.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Kinesin-relat_1 PF12711.2 KXX73331.1 - 0.011 16.0 2.0 0.014 15.8 1.4 1.3 1 0 0 1 1 1 0 Kinesin motor DUF904 PF06005.7 KXX73331.1 - 0.011 15.9 7.0 0.028 14.6 4.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 KXX73331.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.12 KXX73331.1 - 0.019 15.2 1.2 0.027 14.7 0.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Cep57_CLD_2 PF14197.1 KXX73331.1 - 0.023 14.6 1.7 0.023 14.6 1.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.10 KXX73331.1 - 0.045 13.5 1.6 0.045 13.5 1.1 2.8 2 1 1 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.16 KXX73331.1 - 0.052 13.4 1.9 0.052 13.4 1.3 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF4140 PF13600.1 KXX73331.1 - 0.054 13.9 1.5 0.06 13.7 1.0 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FTO_NTD PF12933.2 KXX73331.1 - 0.06 12.4 0.0 0.06 12.4 0.0 1.0 1 0 0 1 1 1 0 FTO catalytic domain UPF0242 PF06785.6 KXX73331.1 - 0.07 11.7 2.3 0.083 11.5 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 KXX73331.1 - 0.094 13.0 3.1 0.16 12.2 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Mto2_bdg PF12808.2 KXX73331.1 - 0.13 12.4 1.1 0.13 12.4 0.8 1.9 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.13 KXX73331.1 - 0.13 12.2 3.6 1.2 9.1 2.5 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family CCDC155 PF14662.1 KXX73331.1 - 0.14 11.7 6.5 65 3.0 0.2 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 IncA PF04156.9 KXX73331.1 - 0.14 11.6 3.2 0.15 11.6 2.2 1.1 1 0 0 1 1 1 0 IncA protein DUF1049 PF06305.6 KXX73331.1 - 0.15 11.5 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TMF_TATA_bd PF12325.3 KXX73331.1 - 0.21 11.3 3.7 0.18 11.5 1.7 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding p450 PF00067.17 KXX73332.1 - 1.3e-24 86.5 0.0 1.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KXX73333.1 - 9.7e-40 136.3 58.7 9.7e-40 136.3 40.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX73333.1 - 3.3e-12 45.4 16.7 3.3e-12 45.4 11.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX73333.1 - 1.2e-08 34.0 13.9 1.2e-08 34.0 9.6 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 KXX73334.1 - 1.4e-34 119.4 0.0 2.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MRP-S24 PF14955.1 KXX73334.1 - 0.18 11.6 0.3 4.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 NAD_binding_8 PF13450.1 KXX73335.1 - 9.3e-12 44.8 0.9 2.4e-11 43.4 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KXX73335.1 - 9.8e-09 34.7 0.8 2.2e-08 33.6 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KXX73335.1 - 1.2e-07 31.2 0.0 2.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KXX73335.1 - 1.4e-05 25.2 0.2 2.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX73335.1 - 3.2e-05 22.5 0.1 4.7e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KXX73335.1 - 3.5e-05 22.8 0.4 3.5e-05 22.8 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX73335.1 - 4.6e-05 23.7 0.1 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73335.1 - 4.7e-05 22.4 0.6 4.7e-05 22.4 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KXX73335.1 - 0.00032 19.8 1.7 0.00036 19.7 0.2 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KXX73335.1 - 0.0023 17.8 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF799 PF05643.6 KXX73335.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) FAD_binding_3 PF01494.14 KXX73335.1 - 0.016 14.3 0.3 0.026 13.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KXX73335.1 - 0.043 12.6 0.2 0.069 12.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.18 KXX73337.1 - 1.6e-21 76.2 0.3 3.6e-21 75.0 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX73337.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like GTP_EFTU PF00009.22 KXX73338.1 - 0.019 14.4 0.1 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ank_2 PF12796.2 KXX73339.1 - 3.3e-63 210.0 0.0 5.4e-17 61.9 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73339.1 - 1.2e-44 147.9 0.8 3e-07 29.9 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KXX73339.1 - 1.8e-38 129.6 8.8 6.6e-08 32.5 0.0 8.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73339.1 - 5.6e-35 115.8 0.0 7.7e-05 22.5 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KXX73339.1 - 3.9e-34 116.4 3.0 7.6e-06 26.2 0.0 7.2 4 2 1 6 6 6 6 Ankyrin repeats (many copies) DUF3716 PF12511.3 KXX73340.1 - 9.3e-17 60.3 1.8 1.5e-16 59.7 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SNARE PF05739.14 KXX73341.1 - 7.6e-09 35.1 1.6 2.1e-08 33.7 1.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KXX73341.1 - 0.031 14.4 1.7 0.97 9.6 0.1 2.4 2 0 0 2 2 2 0 Syntaxin CorA PF01544.13 KXX73341.1 - 0.11 11.5 0.0 0.11 11.5 0.0 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Rifin_STEVOR PF02009.11 KXX73341.1 - 0.13 11.8 0.6 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 Rifin/stevor family Fungal_trans PF04082.13 KXX73342.1 - 1e-11 44.2 0.1 1.4e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73342.1 - 0.0013 18.6 9.9 0.0022 17.8 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1b PF00579.20 KXX73343.1 - 4.6e-79 265.5 0.0 6.4e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RapA_C PF12137.3 KXX73343.1 - 0.9 8.3 5.0 0.7 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal NPR2 PF06218.6 KXX73344.1 - 6.2e-112 374.4 0.0 7.6e-112 374.1 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 zf-RING_2 PF13639.1 KXX73345.1 - 1.9e-12 46.8 5.3 3.4e-12 46.0 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX73345.1 - 2.3e-06 27.2 3.7 3.9e-06 26.5 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX73345.1 - 3e-06 27.1 6.5 5.5e-06 26.3 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX73345.1 - 5.2e-06 26.4 1.9 1.2e-05 25.3 0.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KXX73345.1 - 5.6e-06 25.9 6.1 9.4e-06 25.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX73345.1 - 0.00011 21.9 1.1 0.00025 20.8 0.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KXX73345.1 - 0.00011 21.7 2.6 0.0002 20.9 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX73345.1 - 0.0098 15.5 1.6 0.031 14.0 1.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger DUF1049 PF06305.6 KXX73345.1 - 0.019 14.4 0.5 0.038 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YdjO PF14169.1 KXX73345.1 - 0.04 13.3 0.4 0.53 9.7 0.1 2.4 2 0 0 2 2 2 0 Cold-inducible protein YdjO RINGv PF12906.2 KXX73345.1 - 0.054 13.5 3.0 0.097 12.7 2.1 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KXX73345.1 - 0.067 12.8 2.2 0.12 12.1 1.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KXX73345.1 - 0.16 11.5 2.7 0.27 10.8 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KXX73345.1 - 0.58 10.0 7.1 1.1 9.1 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ada3 PF10198.4 KXX73346.1 - 3.5e-47 159.4 0.1 2.4e-46 156.7 0.0 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3419 PF11899.3 KXX73347.1 - 7.9e-159 528.4 0.0 1e-158 528.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KXX73347.1 - 6.6e-15 55.1 0.0 2.6e-13 50.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX73347.1 - 3.5e-10 40.4 0.0 1.5e-09 38.3 0.0 2.1 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX73347.1 - 2.4e-09 37.5 0.0 1.1e-08 35.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX73347.1 - 2.7e-09 37.0 0.0 3.4e-06 27.0 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX73347.1 - 5.3e-09 35.5 0.0 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KXX73347.1 - 1.4e-08 34.4 0.0 9.7e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KXX73347.1 - 2.6e-07 31.0 0.0 0.0031 17.9 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX73347.1 - 6.3e-05 23.2 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KXX73347.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KXX73347.1 - 0.062 12.3 0.0 0.31 10.0 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 KXX73347.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 KXX73347.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CybS PF05328.7 KXX73348.1 - 1.1e-45 154.5 0.0 1.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KXX73348.1 - 0.019 14.8 0.5 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4238 PF14022.1 KXX73350.1 - 1.4e-29 103.2 0.4 1.9e-29 102.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) HATPase_c_5 PF14501.1 KXX73350.1 - 0.12 12.0 0.1 4.2 7.1 0.0 2.5 2 0 0 2 2 2 0 GHKL domain Pec_lyase_C PF00544.14 KXX73351.1 - 1.6e-41 142.0 4.6 2.6e-41 141.3 3.2 1.3 1 1 0 1 1 1 1 Pectate lyase APH PF01636.18 KXX73352.1 - 6.3e-15 55.5 0.4 1.1e-12 48.2 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX73352.1 - 2.6e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KXX73352.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase EcKinase PF02958.15 KXX73352.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase p450 PF00067.17 KXX73353.1 - 2e-63 214.5 0.0 2.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_B561 PF03188.11 KXX73354.1 - 0.00022 21.0 10.6 0.00075 19.3 6.2 2.5 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.15 KXX73354.1 - 0.11 11.8 11.9 0.019 14.3 2.6 2.3 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF2919 PF11143.3 KXX73354.1 - 1.6 8.5 6.4 9.1 6.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF3951 PF13131.1 KXX73354.1 - 2 8.2 4.3 1.6 8.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF4405 PF14358.1 KXX73354.1 - 2.3 8.4 9.8 8.2 6.6 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) CobD_Cbib PF03186.8 KXX73354.1 - 3.3 6.6 9.8 0.086 11.9 1.4 2.0 2 1 0 2 2 2 0 CobD/Cbib protein YtpI PF14007.1 KXX73354.1 - 9.4 6.2 7.5 1.9 8.4 0.2 2.6 2 1 1 3 3 3 0 YtpI-like protein Glyco_hydro_72 PF03198.9 KXX73355.1 - 5.6e-118 393.4 2.3 7.6e-118 393.0 1.6 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KXX73355.1 - 2.3e-06 27.0 1.0 1.3e-05 24.5 0.7 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_6 PF14259.1 KXX73356.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 KXX73357.1 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73357.1 - 1.3e-10 41.4 0.0 1.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73357.1 - 2.2e-08 34.0 0.1 3.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX73357.1 - 0.034 13.5 0.0 0.16 11.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX73357.1 - 0.047 13.3 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KXX73357.1 - 0.15 12.4 0.6 0.27 11.6 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SMP PF04927.7 KXX73358.1 - 5.8e-13 48.5 13.1 5.8e-10 38.9 1.8 2.1 1 1 1 2 2 2 2 Seed maturation protein DUF2188 PF09954.4 KXX73358.1 - 1.1 9.1 4.0 0.47 10.4 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) adh_short PF00106.20 KXX73359.1 - 2.6e-21 76.2 0.0 1.7e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73359.1 - 1.5e-14 54.3 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KXX73359.1 - 7e-07 28.6 0.0 1.2e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KXX73359.1 - 0.00016 21.4 0.0 0.0045 16.6 0.0 2.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KXX73359.1 - 0.005 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX73359.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX73359.1 - 0.019 14.4 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ABC_tran PF00005.22 KXX73361.1 - 3.9e-06 27.2 0.0 5.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.1 KXX73361.1 - 2.3e-05 24.3 0.1 6.3e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KXX73361.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 KXX73362.1 - 2.7e-40 137.8 49.4 2.4e-20 72.6 8.4 4.1 4 1 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KXX73362.1 - 1.8e-31 107.8 8.5 1e-29 102.2 0.0 3.9 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.22 KXX73362.1 - 4.2e-09 36.8 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KXX73362.1 - 0.0055 15.9 0.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KXX73362.1 - 0.022 14.6 0.0 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 KXX73362.1 - 0.41 9.6 26.6 0.85 8.5 2.4 2.8 2 1 1 3 3 3 0 ABC-2 family transporter protein SurE PF01975.12 KXX73363.1 - 1.2e-40 138.9 0.0 1.6e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 KXX73363.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Methyltransf_16 PF10294.4 KXX73364.1 - 1.4e-08 34.4 0.0 4.4e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KXX73364.1 - 0.00035 21.1 0.0 0.0009 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KXX73364.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KXX73364.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SNF2_N PF00176.18 KXX73366.1 - 2.3e-76 256.4 0.1 7.3e-75 251.5 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX73366.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 KXX73366.1 - 0.0097 15.3 1.4 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 DEAD_2 zf-primase PF09329.6 KXX73367.1 - 3.1e-17 61.9 2.4 5e-17 61.2 1.7 1.3 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 KXX73367.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 KXX73368.1 - 9.3e-85 284.4 0.0 1.2e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Serglycin PF04360.7 KXX73368.1 - 0.014 15.1 5.4 0.03 14.0 3.7 1.7 1 0 0 1 1 1 0 Serglycin DASH_Duo1 PF08651.5 KXX73369.1 - 1.6e-32 110.8 0.5 2.4e-32 110.3 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 KXX73369.1 - 0.00044 19.8 5.0 0.00062 19.3 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF1682 PF07946.9 KXX73369.1 - 0.027 13.3 5.9 0.042 12.7 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Syntaxin-6_N PF09177.6 KXX73369.1 - 0.12 12.8 5.4 0.26 11.7 3.7 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal RNase_H2-Ydr279 PF09468.5 KXX73369.1 - 0.18 10.9 2.1 0.24 10.5 1.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pol_alpha_B_N PF08418.5 KXX73369.1 - 0.54 9.7 5.5 0.14 11.6 1.4 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Atrophin-1 PF03154.10 KXX73369.1 - 0.62 8.1 9.1 0.82 7.7 6.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family EcKinase PF02958.15 KXX73372.1 - 1.8e-18 66.7 0.0 8.4e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KXX73372.1 - 2.2e-11 43.9 0.1 9.1e-11 41.9 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KXX73372.1 - 3.9e-06 25.7 0.0 1.4e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1679) DUF1996 PF09362.5 KXX73376.1 - 7.1e-81 271.3 0.1 8.4e-81 271.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CFEM PF05730.6 KXX73377.1 - 6.1e-12 45.1 7.0 8e-12 44.8 4.9 1.2 1 0 0 1 1 1 1 CFEM domain PRP3 PF08572.5 KXX73378.1 - 3.6e-72 242.3 8.3 5.3e-72 241.8 5.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KXX73378.1 - 1.2e-38 131.7 0.6 2.8e-38 130.4 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1227 PF06777.6 KXX73379.1 - 1.6e-61 206.3 0.1 3.6e-61 205.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KXX73379.1 - 2.8e-51 173.3 0.3 5.3e-51 172.4 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KXX73379.1 - 6.6e-45 153.0 0.1 2.8e-44 151.0 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 KXX73379.1 - 2.7e-06 26.4 0.0 7.1e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 KXX73379.1 - 4.1e-05 23.2 0.2 0.0053 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 KXX73379.1 - 0.001 18.6 0.0 0.39 10.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KXX73379.1 - 0.0032 17.3 1.7 0.013 15.3 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KXX73379.1 - 0.017 14.8 0.0 0.092 12.5 0.0 2.2 3 0 0 3 3 3 0 Part of AAA domain DSBA PF01323.15 KXX73380.1 - 1.6e-16 60.4 0.0 1.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FliG_N PF14842.1 KXX73380.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 FliG N-terminal domain RNA_pol_Rpb1_5 PF04998.12 KXX73381.1 - 3.2e-89 298.8 0.1 6.1e-89 297.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KXX73381.1 - 1.8e-64 216.6 0.1 4.2e-64 215.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KXX73381.1 - 5.3e-33 114.6 1.3 1.3e-21 77.2 0.0 3.1 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KXX73381.1 - 7.5e-32 110.2 0.0 1.7e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KXX73381.1 - 2.2e-18 65.9 0.0 1.4e-17 63.3 0.0 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Histone PF00125.19 KXX73382.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KXX73382.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KXX73382.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KXX73382.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MMS19_N PF14500.1 KXX73384.1 - 3.9e-47 160.7 0.1 9.9e-47 159.3 0.0 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KXX73384.1 - 4.4e-15 55.3 0.1 1.2e-12 47.3 0.0 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal THF_DHG_CYH PF00763.18 KXX73385.1 - 8.3e-21 74.1 0.1 1.2e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KXX73385.1 - 9.2e-14 50.8 0.0 3e-08 32.9 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 KXX73385.1 - 0.0056 15.5 0.0 0.0078 15.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF106 PF01956.11 KXX73386.1 - 7e-56 188.3 1.9 9.1e-56 187.9 1.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 KXX73387.1 - 1.5e-50 170.9 0.1 2e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RNA_pol_Rbc25 PF08292.7 KXX73388.1 - 6.1e-37 126.5 0.0 1.2e-36 125.6 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KXX73388.1 - 4.7e-10 39.4 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Apq12 PF12716.2 KXX73389.1 - 6.4e-10 38.5 14.4 1e-09 37.9 9.9 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF2530 PF10745.4 KXX73389.1 - 8 6.5 17.0 1.9 8.5 3.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2530) ATP_bind_1 PF03029.12 KXX73390.1 - 3.8e-73 245.9 0.1 5e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KXX73390.1 - 2.2e-05 25.2 0.0 5.4e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KXX73390.1 - 0.00039 20.5 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KXX73390.1 - 0.00049 20.0 0.0 0.0014 18.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX73390.1 - 0.0026 17.8 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KXX73390.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KXX73390.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KXX73390.1 - 0.0054 16.1 0.1 0.028 13.8 0.0 2.3 1 1 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 KXX73390.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KXX73390.1 - 0.018 13.6 0.0 0.031 12.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.1 KXX73390.1 - 0.029 14.6 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KXX73390.1 - 0.03 13.8 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.1 KXX73390.1 - 0.038 13.9 0.3 0.16 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Septin PF00735.13 KXX73390.1 - 0.041 12.9 0.0 0.083 11.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 KXX73390.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KXX73390.1 - 0.046 14.0 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 KXX73390.1 - 0.048 13.1 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KXX73390.1 - 0.069 12.5 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KXX73390.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KXX73390.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 KXX73390.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KXX73390.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 KXX73390.1 - 0.13 12.2 0.0 0.47 10.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX73390.1 - 0.13 11.6 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 KXX73390.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) S-AdoMet_synt_C PF02773.11 KXX73391.1 - 1.5e-76 254.7 0.2 2.7e-76 253.9 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KXX73391.1 - 1.5e-46 157.1 0.0 2.6e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KXX73391.1 - 4.7e-41 139.0 0.2 1.3e-40 137.6 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DUF1996 PF09362.5 KXX73392.1 - 6.5e-86 287.8 0.3 8.2e-86 287.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_12 PF13424.1 KXX73394.1 - 1.4e-05 24.9 0.8 0.0013 18.6 1.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73394.1 - 0.00064 19.3 1.8 0.01 15.5 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX73394.1 - 0.0038 17.0 0.3 0.02 14.7 0.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX73394.1 - 0.013 15.1 0.3 0.045 13.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73394.1 - 0.048 14.3 3.6 0.39 11.4 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C PF00271.26 KXX73396.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KXX73396.1 - 1.9e-05 23.6 0.0 0.00011 21.1 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain vMSA PF00695.14 KXX73397.1 - 0.63 9.1 4.8 0.83 8.7 3.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PAT1 PF09770.4 KXX73397.1 - 1.1 7.3 5.9 1.3 7.1 4.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cyclin_N PF00134.18 KXX73398.1 - 8.3e-09 35.0 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spy1 PF11357.3 KXX73398.1 - 0.068 13.2 0.7 6.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein CorA PF01544.13 KXX73399.1 - 3.5e-07 29.5 1.7 7.6e-07 28.4 0.7 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FBPase PF00316.15 KXX73401.1 - 9.7e-57 192.2 0.0 1.2e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase SUR7 PF06687.7 KXX73403.1 - 2.6e-14 53.2 0.5 3.4e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family ABC2_membrane_5 PF13346.1 KXX73403.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF202 PF02656.10 KXX73403.1 - 4 7.7 7.3 2.8 8.2 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Cupredoxin_1 PF13473.1 KXX73404.1 - 0.0059 16.4 0.2 2.1 8.2 0.0 2.7 2 1 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.15 KXX73404.1 - 0.0062 16.7 0.2 3.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family GSDH PF07995.6 KXX73407.1 - 3.5e-116 387.9 0.1 4e-116 387.6 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 KXX73407.1 - 0.00038 20.2 0.0 1.3 9.1 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.6 KXX73407.1 - 0.018 15.0 6.1 1.6 9.0 0.0 4.4 5 0 0 5 5 5 0 Two component regulator propeller HET PF06985.6 KXX73409.1 - 4.9e-19 68.8 0.0 6.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bystin PF05291.6 KXX73411.1 - 5.4e-123 409.7 0.0 7.5e-123 409.2 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 KXX73412.1 - 3.1e-64 216.0 0.0 2.6e-63 213.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KXX73412.1 - 4.9e-24 83.6 0.7 9.5e-24 82.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Adaptin_N PF01602.15 KXX73412.1 - 0.0061 14.9 0.0 0.011 14.0 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region DUF2674 PF10879.3 KXX73412.1 - 0.019 14.6 0.1 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) Proteasom_PSMB PF10508.4 KXX73412.1 - 0.024 12.9 0.0 0.066 11.4 0.0 1.7 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Sugar_tr PF00083.19 KXX73413.1 - 6.1e-41 140.4 17.5 7.9e-41 140.0 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX73413.1 - 3e-19 68.9 26.3 4.4e-19 68.4 18.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.6 KXX73413.1 - 0.23 11.4 0.0 0.47 10.4 0.0 1.4 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Fungal_trans PF04082.13 KXX73414.1 - 1.5e-28 99.4 0.0 2.2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73414.1 - 1.2e-06 28.3 13.6 1.8e-06 27.7 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KXX73415.1 - 3.5e-28 98.3 18.4 5.8e-19 68.0 1.0 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73415.1 - 5.6e-10 38.3 0.7 5.6e-10 38.3 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KXX73415.1 - 0.00058 18.3 0.8 0.00058 18.3 0.6 2.8 3 1 1 4 4 4 1 MFS/sugar transport protein dCMP_cyt_deam_1 PF00383.17 KXX73416.1 - 2e-10 40.2 0.1 3.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Na_H_Exchanger PF00999.16 KXX73417.1 - 4.8e-10 38.5 7.4 6.1e-10 38.1 2.9 2.1 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Ank_5 PF13857.1 KXX73418.1 - 1.7e-14 53.5 1.7 1.1e-11 44.6 0.5 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX73418.1 - 6.7e-14 50.9 2.2 2.5e-09 36.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KXX73418.1 - 9.2e-14 51.5 0.1 1.6e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 KXX73418.1 - 2.5e-12 46.6 0.1 6.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.1 KXX73418.1 - 5.6e-12 45.8 2.9 6.7e-07 29.6 0.3 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73418.1 - 1.5e-09 37.1 0.8 9.1e-06 25.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat MSP1_C PF07462.6 KXX73418.1 - 3.7 5.8 1.4 6.2 5.0 1.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus 6PF2K PF01591.13 KXX73420.1 - 8.9e-62 208.0 0.0 1.2e-39 135.6 0.0 3.1 2 1 1 3 3 3 3 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KXX73420.1 - 7.1e-25 87.9 0.0 3.5e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KXX73420.1 - 1.2e-05 25.1 0.0 7.3e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX73420.1 - 0.023 15.4 0.1 0.14 12.9 0.0 2.4 2 1 1 3 3 3 0 AAA domain DDE_3 PF13358.1 KXX73420.1 - 0.038 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease CARD PF00619.16 KXX73420.1 - 0.041 13.7 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 Caspase recruitment domain KTI12 PF08433.5 KXX73420.1 - 0.049 12.8 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Val_tRNA-synt_C PF10458.4 KXX73420.1 - 0.16 12.0 0.1 27 4.9 0.0 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm IPK PF03770.11 KXX73423.1 - 2.7e-57 193.5 0.0 4.4e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KXX73423.1 - 0.043 13.5 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 ATG27 PF09451.5 KXX73424.1 - 6.4e-76 255.1 0.0 8.6e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 ECH PF00378.15 KXX73425.1 - 7e-19 67.9 0.0 8.2e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KXX73425.1 - 0.0055 16.5 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 TruB_C PF09142.6 KXX73426.1 - 1.4 8.5 6.6 0.12 12.0 1.2 1.8 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Spt20 PF12090.3 KXX73427.1 - 1.3e-47 161.5 0.0 1.3e-47 161.5 0.0 7.4 4 2 0 4 4 4 2 Spt20 family zf-RING_2 PF13639.1 KXX73428.1 - 2.1e-13 49.8 4.6 3.7e-13 49.0 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KXX73428.1 - 2.9e-07 30.0 3.5 4.8e-07 29.3 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX73428.1 - 6.2e-07 29.4 1.1 1.2e-06 28.4 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KXX73428.1 - 5.2e-06 26.3 5.5 9.7e-06 25.5 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX73428.1 - 1.2e-05 24.8 1.7 2.1e-05 24.1 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KXX73428.1 - 0.00058 19.4 1.6 0.0012 18.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX73428.1 - 0.012 15.4 1.8 0.024 14.4 1.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KXX73428.1 - 0.18 11.3 2.5 0.31 10.6 1.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KXX73428.1 - 0.28 11.2 1.9 0.46 10.5 1.3 1.4 1 0 0 1 1 1 0 RING-like domain Dicty_REP PF05086.7 KXX73428.1 - 2.1 5.9 3.1 3.1 5.4 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_cc PF11790.3 KXX73429.1 - 7.2e-57 192.5 0.2 9.2e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mito_fiss_reg PF05308.6 KXX73429.1 - 0.074 12.4 9.5 0.11 11.8 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KXX73429.1 - 1.3 8.2 9.5 1.9 7.6 6.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Zn_clus PF00172.13 KXX73430.1 - 2e-08 33.9 9.0 3.4e-08 33.2 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 KXX73430.1 - 0.092 12.4 0.6 0.15 11.7 0.4 1.3 1 0 0 1 1 1 0 Serglycin CAP_GLY PF01302.20 KXX73431.1 - 3.3e-22 77.9 1.8 4.7e-22 77.4 1.3 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KXX73431.1 - 1.6e-17 63.5 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KXX73431.1 - 3e-06 26.5 0.0 6.6e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Bromodomain PF00439.20 KXX73434.1 - 9.2e-25 86.3 0.1 1.7e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KXX73434.1 - 3.1e-09 36.8 0.2 6.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX73434.1 - 3.8e-09 36.4 0.3 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Sulfate_transp PF00916.15 KXX73435.1 - 2.6e-06 26.6 1.3 2.6e-06 26.6 0.9 2.8 2 1 1 3 3 3 1 Sulfate transporter family DUF3638 PF12340.3 KXX73436.1 - 2.9e-96 320.8 0.0 4.7e-96 320.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KXX73436.1 - 1.7e-15 55.8 0.1 3.5e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Fer4_19 PF06902.6 KXX73436.1 - 0.13 12.1 0.3 3.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster eIF3_N PF09440.5 KXX73438.1 - 2.4e-51 173.3 4.1 6.8e-51 171.9 2.9 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KXX73438.1 - 2.8e-14 53.3 0.1 6.7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KXX73438.1 - 0.0028 17.4 0.1 0.0064 16.2 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 KXX73438.1 - 0.078 12.9 0.6 0.46 10.4 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc1 PF12859.2 KXX73439.1 - 1.5e-27 95.8 0.1 4.5e-27 94.3 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KXX73439.1 - 5.2e-10 38.9 0.1 0.0017 18.4 0.0 4.4 3 0 0 3 3 3 3 Proteasome/cyclosome repeat ARID PF01388.16 KXX73440.1 - 3.4e-15 55.6 0.0 9.2e-15 54.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 KXX73441.1 - 3.3e-20 72.1 0.0 4.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 KXX73441.1 - 0.00063 19.5 0.6 0.0014 18.4 0.4 1.5 1 1 0 1 1 1 1 Translation initiation factor SUI1 Clathrin PF00637.15 KXX73442.1 - 2.9e-15 56.1 0.8 1.2e-14 54.1 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KXX73442.1 - 1.9e-06 27.4 1.1 0.0013 18.5 0.2 3.4 2 1 0 2 2 2 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 KXX73442.1 - 0.049 13.4 4.8 0.18 11.6 3.3 2.0 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 KXX73442.1 - 0.19 11.4 4.1 0.039 13.6 0.3 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Spore_coat_CotO PF14153.1 KXX73442.1 - 4.6 6.6 40.4 9.1 5.6 28.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 KXX73442.1 - 5 5.6 22.9 8.7 4.8 15.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.7 KXX73442.1 - 5.9 6.6 35.0 13 5.5 24.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-T PF15511.1 KXX73442.1 - 9.8 5.3 42.2 24 3.9 29.2 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GST_N PF02798.15 KXX73443.1 - 3.6e-09 36.6 0.0 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX73443.1 - 5.5e-08 32.9 0.0 9.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX73443.1 - 1.2e-07 31.6 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KXX73443.1 - 6.7e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX73443.1 - 4.2e-05 23.3 0.0 8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX73443.1 - 4.3e-05 23.9 0.0 7.3e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HET PF06985.6 KXX73444.1 - 0.00013 22.1 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cu-oxidase_2 PF07731.9 KXX73444.1 - 0.013 14.9 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Multicopper oxidase Glyco_trans_4_4 PF13579.1 KXX73444.1 - 0.044 13.9 0.7 0.34 11.0 0.1 2.0 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain SKIP_SNW PF02731.10 KXX73445.1 - 6.1e-57 191.4 3.9 6.1e-57 191.4 2.7 2.9 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 KXX73445.1 - 0.66 7.0 14.6 0.86 6.7 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.1 KXX73445.1 - 5.5 6.6 9.7 11 5.6 6.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Tim17 PF02466.14 KXX73447.1 - 9.3e-48 161.4 11.3 1.3e-47 161.0 7.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KXX73447.1 - 0.051 13.5 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glyco_hydro_16 PF00722.16 KXX73448.1 - 5.5e-09 35.5 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Herpes_gE PF02480.11 KXX73448.1 - 0.062 11.5 0.1 0.098 10.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VirB8 PF04335.8 KXX73448.1 - 8.4 5.8 7.8 17 4.9 1.9 2.2 2 0 0 2 2 2 0 VirB8 protein BCDHK_Adom3 PF10436.4 KXX73449.1 - 8.4e-45 152.2 1.2 9.8e-45 152.0 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KXX73449.1 - 7.8e-10 38.4 0.2 5e-07 29.4 0.1 2.6 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KXX73449.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 KXX73450.1 - 3.4e-86 288.5 0.0 4.9e-84 281.4 0.0 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KXX73450.1 - 5e-76 254.8 2.9 1.2e-71 240.5 0.2 3.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KXX73450.1 - 1e-55 188.7 2.5 2.2e-55 187.6 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX73450.1 - 2.1e-29 102.9 0.1 3.4e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KXX73450.1 - 3.2e-14 53.1 0.1 3.9e-13 49.6 0.1 2.7 2 0 0 2 2 2 1 MATH domain WD40 PF00400.27 KXX73451.1 - 1.9e-56 186.0 29.2 3.1e-12 45.8 0.0 12.7 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 KXX73451.1 - 2.7e-16 59.4 0.0 4.1e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KXX73451.1 - 1.7e-07 31.1 2.7 0.02 14.5 0.0 6.5 4 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KXX73451.1 - 7.2e-06 24.4 0.8 0.18 9.9 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX73451.1 - 0.0002 20.2 3.4 7.1 5.2 0.0 5.0 1 1 2 3 3 3 2 Nup133 N terminal like IKI3 PF04762.7 KXX73451.1 - 0.00033 18.6 0.0 0.028 12.2 0.0 2.4 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 KXX73451.1 - 0.0027 16.8 0.2 7 5.6 0.0 4.1 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KXX73452.1 - 6.3e-117 389.5 0.4 9.1e-117 389.0 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KXX73452.1 - 5.9e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX73452.1 - 2.5e-06 27.0 0.4 5.7e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KXX73452.1 - 1.1e-05 24.7 0.0 2.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KXX73452.1 - 0.0024 18.3 0.1 0.0081 16.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KXX73452.1 - 0.0033 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX73452.1 - 0.0039 17.3 0.4 0.015 15.3 0.0 2.1 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KXX73452.1 - 0.0054 16.2 0.1 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 KXX73452.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KXX73452.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 KXX73452.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KXX73452.1 - 0.017 14.4 0.6 0.054 12.8 0.4 1.9 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 KXX73452.1 - 0.034 13.0 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 KXX73452.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KXX73452.1 - 0.046 14.0 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 KXX73452.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KXX73452.1 - 0.071 13.0 3.0 0.36 10.8 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 KXX73452.1 - 0.078 11.7 2.2 0.91 8.2 0.0 2.9 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 KXX73452.1 - 0.08 12.7 7.3 0.7 9.6 0.1 3.1 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 KXX73452.1 - 0.087 12.3 0.8 2.8 7.4 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KXX73452.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 KXX73452.1 - 0.14 12.4 4.8 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e KAP_NTPase PF07693.9 KXX73452.1 - 0.18 10.7 2.6 0.33 9.8 1.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KXX73452.1 - 0.29 10.6 1.1 9.4 5.6 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Val_tRNA-synt_C PF10458.4 KXX73452.1 - 0.69 10.0 6.6 0.16 12.0 0.9 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Atg14 PF10186.4 KXX73452.1 - 0.69 8.7 7.2 1.7 7.5 5.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 KXX73452.1 - 8.3 6.1 13.6 4.5 6.9 4.5 3.1 2 1 0 2 2 2 0 Myc leucine zipper domain adh_short PF00106.20 KXX73454.1 - 7.7e-18 64.9 1.7 1.2e-17 64.3 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73454.1 - 0.00023 20.9 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73454.1 - 0.0027 17.3 1.4 0.0049 16.5 1.0 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX73454.1 - 0.12 12.1 0.6 0.28 10.9 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4514 PF14986.1 KXX73454.1 - 0.27 11.0 1.4 0.64 9.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) AAA PF00004.24 KXX73455.1 - 2.7e-14 53.4 0.0 7.7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX73455.1 - 0.0022 17.7 0.0 0.012 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX73455.1 - 0.0029 17.5 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX73455.1 - 0.0053 16.8 0.3 0.16 12.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX73455.1 - 0.01 16.6 0.1 0.06 14.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX73455.1 - 0.028 14.1 0.3 0.074 12.8 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KXX73455.1 - 0.091 12.6 0.3 0.33 10.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain CPT PF07931.7 KXX73455.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.7 KXX73455.1 - 0.19 10.7 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Response_reg PF00072.19 KXX73456.1 - 1.8e-19 69.8 0.0 8.4e-18 64.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KXX73456.1 - 5.2e-18 64.7 0.1 1.2e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KXX73456.1 - 1.5e-09 37.7 0.4 4.2e-09 36.2 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MxiH PF09392.5 KXX73458.1 - 0.25 11.9 2.1 2.1 8.9 1.5 2.0 1 1 0 1 1 1 0 Type III secretion needle MxiH like Ank_2 PF12796.2 KXX73459.1 - 6.7e-16 58.4 0.1 9.7e-08 32.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX73459.1 - 3.1e-13 49.8 0.1 5.1e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX73459.1 - 2.5e-11 42.7 10.2 2.5e-05 23.8 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KXX73459.1 - 2.5e-10 40.2 5.3 6.6e-05 23.0 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73459.1 - 7.8e-09 34.9 3.1 0.0035 17.4 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Glycoprotein_B PF00606.13 KXX73459.1 - 0.21 9.6 0.0 0.31 9.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Sex_peptide PF08138.6 KXX73460.1 - 0.11 12.3 0.8 0.36 10.7 0.5 1.8 1 1 0 1 1 1 0 Sex peptide (SP) family ketoacyl-synt PF00109.21 KXX73461.1 - 2.2e-20 73.2 0.0 2.7e-17 63.0 0.0 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_114 PF03537.8 KXX73462.1 - 3.1e-06 26.8 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 TPR_11 PF13414.1 KXX73464.1 - 4.5e-19 67.8 10.0 4.2e-16 58.3 4.8 2.7 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KXX73464.1 - 3.1e-16 58.2 6.7 1.1e-06 27.9 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX73464.1 - 1.6e-14 52.5 9.1 6.7e-06 25.6 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73464.1 - 3.8e-09 36.0 5.6 0.00097 19.1 0.2 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX73464.1 - 1.3e-07 32.0 17.4 2.8e-05 24.6 2.7 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73464.1 - 3.7e-07 30.1 12.2 0.0016 18.9 0.4 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73464.1 - 1e-06 28.0 0.4 0.0099 15.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX73464.1 - 3.3e-06 26.9 8.9 0.005 16.7 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX73464.1 - 2.9e-05 24.3 3.0 2.9e-05 24.3 2.1 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX73464.1 - 5e-05 22.7 6.8 0.77 9.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KXX73464.1 - 0.00065 19.5 1.6 0.006 16.4 0.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 KXX73464.1 - 0.0071 15.7 3.2 0.0096 15.3 1.2 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_10 PF13374.1 KXX73464.1 - 0.013 15.4 5.9 1.5 8.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 KXX73464.1 - 0.013 15.7 7.5 0.7 10.1 0.3 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KXX73464.1 - 0.48 10.9 11.0 3.4 8.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat FAA_hydrolase PF01557.13 KXX73465.1 - 3.3e-16 59.4 0.0 3.7e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 KXX73466.1 - 1.8e-24 85.8 0.0 1.9e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase TPP_enzyme_C PF02775.16 KXX73467.1 - 6.4e-51 171.9 0.6 1e-49 168.0 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KXX73467.1 - 1.1e-40 138.9 0.3 5.5e-40 136.6 0.2 2.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KXX73467.1 - 7.9e-38 129.3 1.2 5e-37 126.7 0.3 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GATase_5 PF13507.1 KXX73468.1 - 3.4e-98 327.6 0.0 5.2e-98 327.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KXX73468.1 - 1.9e-39 135.0 1.1 9.1e-22 77.7 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KXX73468.1 - 1.2e-24 86.4 0.1 9.2e-24 83.5 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain zf-C2H2 PF00096.21 KXX73469.1 - 0.01 16.1 8.7 0.45 10.9 0.3 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX73469.1 - 0.023 14.9 10.1 0.049 13.9 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.7 KXX73469.1 - 3.1 6.2 6.4 0.8 8.1 2.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF629) GalKase_gal_bdg PF10509.4 KXX73470.1 - 1.2e-19 69.3 0.0 2.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KXX73470.1 - 5.1e-14 52.0 1.9 1.4e-13 50.6 1.3 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KXX73470.1 - 1.7e-12 47.3 0.0 4.7e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 KXX73470.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RINGv PF12906.2 KXX73471.1 - 1.6e-05 24.8 6.9 2.7e-05 24.1 4.8 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KXX73471.1 - 8.2e-05 22.3 6.6 0.00013 21.7 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KXX73471.1 - 0.00018 21.4 4.0 0.00033 20.5 2.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KXX73471.1 - 0.015 14.9 4.8 0.023 14.3 3.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KXX73471.1 - 0.24 10.9 4.1 0.45 10.1 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KXX73471.1 - 0.29 11.2 4.7 0.58 10.2 3.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KXX73471.1 - 1.9 8.6 5.5 3.2 7.8 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX73471.1 - 3 7.5 6.0 5 6.8 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FNIP_N PF14636.1 KXX73472.1 - 3.1e-33 115.0 0.2 3.1e-33 115.0 0.1 4.1 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 KXX73472.1 - 0.09 12.1 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus FNIP_M PF14637.1 KXX73472.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Baculo_PP31 PF05311.6 KXX73472.1 - 0.24 10.6 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zn_clus PF00172.13 KXX73473.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX73473.1 - 5.1e-08 32.0 0.3 1.1e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lactonase PF10282.4 KXX73474.1 - 9.1e-81 271.6 0.0 1e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NTPase_I-T PF01931.13 KXX73475.1 - 2.2e-46 157.6 0.0 2.7e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Glyco_hydro_43 PF04616.9 KXX73476.1 - 1.6e-24 86.5 0.6 2.5e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DnaJ PF00226.26 KXX73477.1 - 2.6e-20 71.9 1.6 4.6e-20 71.1 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KXX73477.1 - 0.014 15.3 0.3 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Tyrosinase PF00264.15 KXX73478.1 - 2.4e-46 158.6 0.6 3.1e-46 158.3 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase GMC_oxred_N PF00732.14 KXX73479.1 - 3.6e-47 160.9 0.0 4.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73479.1 - 0.00056 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX73479.1 - 0.0019 18.1 0.2 0.021 14.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX73479.1 - 0.0097 14.8 0.1 0.25 10.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX73479.1 - 0.016 14.1 0.2 0.027 13.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KXX73479.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KXX73479.1 - 0.026 13.3 0.0 5.1 5.8 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain SpoIIIAH PF12685.2 KXX73480.1 - 0.0068 15.9 2.8 0.0068 15.9 1.9 1.7 2 0 0 2 2 2 1 SpoIIIAH-like protein SpoIIP PF07454.6 KXX73480.1 - 0.011 14.8 2.3 0.011 14.8 1.6 1.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Arena_nucleocap PF00843.12 KXX73480.1 - 0.013 13.4 0.5 0.041 11.7 0.6 1.6 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein Dynamin_N PF00350.18 KXX73480.1 - 0.1 12.3 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Dynamin family TMEM247 PF15444.1 KXX73480.1 - 0.15 11.8 3.5 0.23 11.2 2.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 AAA_23 PF13476.1 KXX73480.1 - 0.23 11.7 6.1 0.3 11.3 4.2 1.2 1 0 0 1 1 1 0 AAA domain Casc1 PF12366.3 KXX73480.1 - 0.63 9.5 7.4 1.1 8.7 5.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF4557 PF15101.1 KXX73480.1 - 4.1 7.1 14.7 2.6 7.8 8.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Terpene_synth_C PF03936.11 KXX73481.1 - 3.4e-08 33.0 0.5 5.3e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4096 PF13340.1 KXX73481.1 - 0.0075 16.1 1.0 0.037 13.8 0.1 2.4 2 1 1 3 3 3 1 Putative transposase of IS4/5 family (DUF4096) ANTAR PF03861.9 KXX73481.1 - 0.018 14.5 0.6 0.069 12.7 0.1 2.2 2 0 0 2 2 2 0 ANTAR domain p450 PF00067.17 KXX73482.1 - 8.8e-44 149.7 0.0 9.1e-42 143.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.26 KXX73483.1 - 4.4e-11 42.3 0.8 1e-10 41.1 0.6 1.7 1 1 0 1 1 1 1 DnaJ domain HTH_20 PF12840.2 KXX73484.1 - 0.085 12.6 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4269 PF14091.1 KXX73484.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) GATA PF00320.22 KXX73486.1 - 1.6e-16 59.3 1.9 3.2e-16 58.3 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KXX73486.1 - 5.9e-11 41.7 0.3 1.2e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CFEM PF05730.6 KXX73487.1 - 0.21 11.4 7.6 0.17 11.7 4.3 1.5 1 1 0 1 1 1 0 CFEM domain Pkinase PF00069.20 KXX73488.1 - 1.2e-58 198.2 0.0 7e-58 195.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73488.1 - 2.6e-28 98.8 0.3 2.3e-20 72.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KXX73488.1 - 1.5e-07 31.8 1.9 1.4e-06 28.7 0.3 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KXX73488.1 - 0.00046 19.2 0.4 0.002 17.1 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KXX73488.1 - 0.0049 16.6 0.1 0.11 12.1 0.0 2.8 3 1 1 4 4 4 1 Phosphotransferase enzyme family Wbp11 PF09429.5 KXX73489.1 - 6.8e-24 83.6 16.1 6.8e-24 83.6 11.2 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2294 PF10057.4 KXX73489.1 - 0.054 13.1 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 KXX73489.1 - 0.074 12.1 5.4 0.11 11.5 3.7 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 KXX73489.1 - 0.4 9.9 6.4 0.57 9.4 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 KXX73489.1 - 2.4 7.0 7.5 4.1 6.2 5.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_3 PF01494.14 KXX73490.1 - 1.8e-44 152.2 0.0 2.8e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX73490.1 - 2.1e-06 26.9 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX73490.1 - 5.6e-05 23.0 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX73490.1 - 9.9e-05 21.4 0.8 0.015 14.2 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 KXX73490.1 - 0.0004 20.7 0.1 0.081 13.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX73490.1 - 0.00085 17.9 0.1 0.003 16.0 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KXX73490.1 - 0.006 15.7 0.1 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 KXX73490.1 - 0.023 13.3 0.6 2 6.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX73490.1 - 0.027 14.2 0.4 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX73490.1 - 0.038 13.8 0.1 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX73490.1 - 0.15 12.0 0.1 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CFEM PF05730.6 KXX73491.1 - 4.6e-14 51.9 10.1 8.7e-14 51.1 7.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF3953 PF13129.1 KXX73491.1 - 0.67 9.6 0.0 0.67 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF1857 PF08982.6 KXX73493.1 - 4.4e-46 156.1 0.1 4.8e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Pro_CA PF00484.14 KXX73494.1 - 2.2e-13 50.5 0.0 2.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SAM_decarbox PF01536.11 KXX73495.1 - 7.2e-87 291.1 0.0 2.6e-62 210.4 0.0 3.1 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase Sigma70_ner PF04546.8 KXX73496.1 - 0.2 11.2 6.2 0.15 11.7 0.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KXX73496.1 - 0.81 9.1 5.1 0.21 11.0 0.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin ParA PF10609.4 KXX73497.1 - 1.7e-36 123.9 0.1 3.2e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KXX73497.1 - 4.6e-14 52.2 0.0 1e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KXX73497.1 - 6.7e-07 28.6 0.0 1.2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KXX73497.1 - 5.5e-06 25.6 0.5 1.1e-05 24.7 0.2 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 KXX73497.1 - 4e-05 23.5 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KXX73497.1 - 0.00023 20.0 0.4 0.00036 19.3 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 KXX73497.1 - 0.0024 17.3 0.1 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KXX73497.1 - 0.0025 17.2 0.1 0.0047 16.3 0.1 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_26 PF13500.1 KXX73497.1 - 0.0051 16.4 0.2 1.8 8.1 0.3 2.4 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KXX73497.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 KXX73497.1 - 0.071 13.0 0.6 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KXX73497.1 - 0.083 12.3 0.0 0.2 11.0 0.1 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KXX73497.1 - 0.088 11.9 0.7 0.19 10.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KXX73497.1 - 0.14 11.8 0.3 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Transferase PF02458.10 KXX73498.1 - 3.9e-13 48.6 0.0 1.8e-09 36.5 0.0 3.0 2 1 1 3 3 3 3 Transferase family p450 PF00067.17 KXX73499.1 - 2.9e-91 306.3 0.0 3.3e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1b PF00579.20 KXX73501.1 - 0.24 10.5 0.0 14 4.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) HCV_NS1 PF01560.12 KXX73502.1 - 0.17 10.2 1.9 0.2 10.1 1.3 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 Spherulin4 PF12138.3 KXX73503.1 - 3.8e-33 114.9 0.0 7.6e-22 77.9 0.0 2.1 1 1 1 2 2 2 2 Spherulation-specific family 4 CAP PF00188.21 KXX73503.1 - 0.051 14.0 0.7 0.1 13.1 0.3 1.6 1 1 1 2 2 2 0 Cysteine-rich secretory protein family NACHT PF05729.7 KXX73504.1 - 0.00049 19.8 0.2 0.016 14.8 0.1 2.7 2 1 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 KXX73504.1 - 0.0043 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KXX73504.1 - 0.01 16.6 0.0 0.037 14.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX73504.1 - 0.018 15.3 0.1 0.18 12.0 0.0 2.3 2 1 1 3 3 3 0 ABC transporter ArgK PF03308.11 KXX73504.1 - 0.021 13.5 0.0 0.074 11.8 0.0 1.8 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 KXX73504.1 - 0.024 14.8 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX73504.1 - 0.025 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX73504.1 - 0.027 14.6 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KXX73504.1 - 0.035 13.5 0.1 0.081 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 KXX73504.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Glyco_hydro_43 PF04616.9 KXX73505.1 - 4.6e-66 222.8 2.8 5.8e-66 222.4 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 KXX73506.1 - 8e-33 113.6 0.0 1.2e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_2 PF12706.2 KXX73507.1 - 2.8e-11 43.3 0.0 6.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX73507.1 - 3.8e-06 26.6 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 KXX73507.1 - 2.3e-05 24.3 0.0 7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 KXX73507.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Glyco_hydro_43 PF04616.9 KXX73508.1 - 0.0042 16.2 0.3 0.0082 15.2 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KXX73508.1 - 0.083 12.2 0.0 0.31 10.3 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.13 KXX73509.1 - 1.4e-08 34.5 11.8 2.2e-08 33.8 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.5 KXX73509.1 - 4.4 6.9 6.7 7.7 6.2 4.6 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Pantoate_transf PF02548.10 KXX73510.1 - 1.4e-105 352.1 0.2 1.7e-105 351.8 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KXX73510.1 - 8.5e-11 41.5 1.0 1.1e-10 41.1 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 KXX73511.1 - 1e-25 89.7 0.0 1.3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KXX73511.1 - 6.5e-05 22.8 0.0 8.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF572 PF04502.8 KXX73512.1 - 2.6e-55 187.9 0.0 2.9e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1778 PF08681.6 KXX73512.1 - 0.013 15.2 0.1 0.039 13.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2526 PF10735.4 KXX73512.1 - 0.55 10.2 3.1 1.1 9.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) UQ_con PF00179.21 KXX73513.1 - 9.7e-35 119.0 0.0 1.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ApbA PF02558.11 KXX73514.1 - 4.5e-21 74.8 0.0 6.7e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KXX73514.1 - 6.2e-21 74.6 0.0 1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 KXX73515.1 - 7e-22 77.3 5.8 9.8e-22 76.8 4.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like YPEB PF14620.1 KXX73515.1 - 0.03 13.3 0.1 0.032 13.2 0.1 1.0 1 0 0 1 1 1 0 YpeB sporulation BBS2_C PF14782.1 KXX73515.1 - 0.052 12.1 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Mating_C PF12737.2 KXX73515.1 - 0.1 11.4 0.4 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 FlxA PF14282.1 KXX73515.1 - 0.1 12.5 1.9 0.12 12.3 1.3 1.1 1 0 0 1 1 1 0 FlxA-like protein ICAT PF06384.6 KXX73515.1 - 0.12 12.1 0.4 0.26 11.0 0.2 1.6 1 1 1 2 2 2 0 Beta-catenin-interacting protein ICAT Rpr2 PF04032.11 KXX73516.1 - 6.9e-22 77.1 0.0 9.5e-22 76.6 0.0 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 KXX73516.1 - 0.007 16.1 1.1 1.3 8.8 0.1 2.3 2 0 0 2 2 2 2 BED zinc finger DEAD PF00270.24 KXX73517.1 - 7.3e-38 129.6 0.0 1.2e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX73517.1 - 3.4e-24 84.4 0.0 6.1e-23 80.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX73517.1 - 4.6e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KXX73517.1 - 0.091 11.8 0.0 0.64 9.0 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Cyclin PF08613.6 KXX73518.1 - 1.3e-13 51.6 0.2 4.8e-13 49.7 0.0 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KXX73518.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain VP4_haemagglut PF00426.13 KXX73518.1 - 5.9 4.7 5.0 8.8 4.1 3.5 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) MFS_1 PF07690.11 KXX73519.1 - 2.6e-38 131.6 49.0 2.6e-38 131.6 33.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73519.1 - 8.5e-11 41.0 14.8 8.5e-11 41.0 10.2 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KXX73519.1 - 7.7e-08 30.9 24.1 1.1e-07 30.4 16.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TRAP-gamma PF07074.7 KXX73519.1 - 6 6.3 5.8 5.4 6.5 0.6 2.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) UbiA PF01040.13 KXX73520.1 - 3.1e-20 72.4 7.6 4.7e-20 71.8 5.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Flu_M2 PF00599.12 KXX73521.1 - 0.029 14.1 2.6 0.21 11.3 0.3 2.6 1 1 1 2 2 2 0 Influenza Matrix protein (M2) p450 PF00067.17 KXX73522.1 - 1.9e-55 188.2 0.0 2.4e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KXX73523.1 - 7.1e-60 202.6 0.0 9.9e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73523.1 - 1.8e-32 112.6 0.1 5.8e-32 110.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX73523.1 - 7.5e-10 38.2 0.0 1.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX73523.1 - 2.1e-08 33.4 0.6 2.6e-05 23.3 0.0 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX73523.1 - 9.3e-07 28.0 0.0 3.1e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX73523.1 - 2.5e-05 24.2 0.0 0.00028 20.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX73523.1 - 0.00011 22.1 0.1 0.00041 20.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX73523.1 - 0.00018 21.6 0.1 0.21 11.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX73523.1 - 0.0015 18.8 0.1 0.02 15.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX73523.1 - 0.0016 17.0 0.3 0.0032 15.9 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KXX73523.1 - 0.0026 16.9 0.1 0.0053 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 KXX73523.1 - 0.0029 16.5 0.0 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 KXX73523.1 - 0.0043 17.0 0.6 0.019 14.9 0.0 2.3 3 0 0 3 3 3 1 TrkA-N domain FAD_binding_3 PF01494.14 KXX73523.1 - 0.013 14.6 0.1 0.062 12.3 0.0 2.0 2 1 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KXX73523.1 - 0.017 14.8 0.8 0.079 12.7 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KXX73523.1 - 0.026 13.1 0.1 0.039 12.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_4 PF01565.18 KXX73524.1 - 1.3e-25 89.5 1.4 2.3e-25 88.6 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX73524.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like DUF605 PF04652.11 KXX73526.1 - 5.5 6.2 8.1 7.9 5.7 5.6 1.3 1 0 0 1 1 1 0 Vta1 like CNH PF00780.17 KXX73527.1 - 2.1e-79 266.8 0.0 6.2e-79 265.2 0.0 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KXX73527.1 - 2.9e-41 140.5 1.7 1.2e-40 138.5 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 KXX73527.1 - 3.8e-34 118.1 0.0 8.1e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KXX73527.1 - 3.8e-15 55.3 0.1 7.3e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_S9_N PF02897.10 KXX73527.1 - 0.3 9.5 0.0 0.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain SH3_1 PF00018.23 KXX73528.1 - 1.7e-14 52.9 0.1 2.6e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX73528.1 - 2.9e-11 42.7 0.1 5.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX73528.1 - 4.5e-09 35.6 0.0 6.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_C PF00137.16 KXX73530.1 - 7e-27 93.1 30.9 1.1e-15 57.2 6.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Metallophos PF00149.23 KXX73531.1 - 8.1e-07 28.6 5.5 1.7e-06 27.5 3.8 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L22 PF00237.14 KXX73531.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e DLH PF01738.13 KXX73532.1 - 2e-20 73.0 0.1 1e-18 67.4 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX73532.1 - 7e-08 32.3 0.3 1.1e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX73532.1 - 3e-07 30.5 0.7 4.9e-05 23.3 0.1 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX73532.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 KXX73533.1 - 2e-23 82.3 0.2 3.3e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX73533.1 - 2e-19 70.7 0.0 6.2e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX73533.1 - 2.3e-11 43.4 0.0 1.5e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RVT_thumb PF06817.9 KXX73534.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Isy1 PF06246.7 KXX73535.1 - 9.5e-86 287.3 0.8 1.9e-85 286.3 0.5 1.4 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KXX73535.1 - 0.017 14.9 0.1 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 YolD-like protein CybS PF05328.7 KXX73536.1 - 1.1e-45 154.5 0.0 1.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KXX73536.1 - 0.019 14.8 0.5 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ZZ PF00569.12 KXX73537.1 - 6.7e-12 44.7 8.1 1.2e-11 43.9 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KXX73537.1 - 6e-10 37.7 4.0 4.5e-05 22.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KXX73537.1 - 4e-08 33.2 7.1 0.00025 21.1 0.2 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.1 KXX73537.1 - 1.6e-06 27.5 1.9 0.036 13.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KXX73537.1 - 6.6e-06 25.5 9.2 0.00027 20.5 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 KXX73537.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand C1_3 PF07649.7 KXX73537.1 - 0.24 11.4 8.8 0.41 10.7 6.1 1.4 1 0 0 1 1 1 0 C1-like domain Vps53_N PF04100.7 KXX73539.1 - 4.8e-101 338.3 0.2 7.6e-101 337.6 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 KXX73539.1 - 4.3e-06 25.1 0.0 7.3e-05 21.0 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF2450 PF10475.4 KXX73539.1 - 1.5e-05 24.0 3.2 3e-05 23.0 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KXX73539.1 - 0.0025 16.0 2.2 0.0048 15.1 1.5 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF2451 PF10474.4 KXX73539.1 - 0.011 15.5 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.6 KXX73539.1 - 0.017 13.7 0.5 0.033 12.8 0.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Rbsn PF11464.3 KXX73539.1 - 0.029 13.9 0.3 0.098 12.2 0.2 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Sec15 PF04091.7 KXX73539.1 - 0.05 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like tRNA-synt_1b PF00579.20 KXX73540.1 - 4.6e-79 265.5 0.0 6.4e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RapA_C PF12137.3 KXX73540.1 - 0.74 8.5 4.5 0.7 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal NPR2 PF06218.6 KXX73541.1 - 3.4e-118 395.0 0.0 4.1e-118 394.7 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 NUDIX PF00293.23 KXX73543.1 - 0.14 11.8 0.0 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain Prenyltrans_2 PF13249.1 KXX73544.1 - 5.7e-08 33.1 0.2 0.16 12.3 0.0 4.5 4 0 0 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KXX73544.1 - 0.00026 20.9 0.0 0.34 10.9 0.0 3.9 4 0 0 4 4 4 2 Prenyltransferase-like Pyr_redox_3 PF13738.1 KXX73546.1 - 2.4e-15 57.1 0.0 4e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX73546.1 - 4.6e-10 39.3 0.0 1.4e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KXX73546.1 - 1.8e-07 29.7 0.1 2.4e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Thi4 PF01946.12 KXX73546.1 - 2.6e-05 23.4 0.0 0.00027 20.0 0.0 2.4 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KXX73546.1 - 6.9e-05 21.9 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX73546.1 - 0.0001 21.3 0.7 0.00039 19.4 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 KXX73546.1 - 0.0073 16.6 0.0 0.34 11.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KXX73546.1 - 0.021 13.8 0.0 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KXX73546.1 - 0.049 13.4 0.1 0.36 10.6 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX73546.1 - 0.1 11.5 0.0 5.9 5.6 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SnoaL_4 PF13577.1 KXX73547.1 - 4.2e-45 152.7 4.3 1.3e-19 70.3 0.4 3.6 4 0 0 4 4 4 3 SnoaL-like domain Glyco_hydro_31 PF01055.21 KXX73549.1 - 9.7e-96 321.2 1.3 2.1e-95 320.1 0.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX73549.1 - 4.8e-06 26.3 1.1 1.4e-05 24.8 0.8 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like AAA PF00004.24 KXX73550.1 - 7.3e-07 29.4 0.0 6.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_MA_2 PF13485.1 KXX73551.1 - 0.00039 20.4 0.6 0.00075 19.5 0.4 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KXX73551.1 - 0.13 12.2 2.1 0.67 9.9 1.5 2.0 1 1 0 1 1 1 0 M61 glycyl aminopeptidase fn3 PF00041.16 KXX73552.1 - 2.6e-11 43.4 0.2 7.3e-05 22.8 0.0 3.9 3 1 0 3 3 3 3 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 KXX73552.1 - 8.8e-09 35.7 4.5 1.2e-08 35.3 1.1 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX73552.1 - 0.00035 20.4 0.0 0.0036 17.1 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SAPS PF04499.10 KXX73553.1 - 3.1e-190 632.8 0.0 7.9e-190 631.5 0.0 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein adh_short PF00106.20 KXX73554.1 - 1.5e-17 64.0 1.3 1.5e-17 64.0 0.9 2.0 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 KXX73554.1 - 1.2e-09 38.1 2.6 3e-09 36.7 0.7 2.3 2 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KXX73554.1 - 0.0045 17.0 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KXX73554.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KXX73554.1 - 0.013 14.9 0.1 0.18 11.2 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.10 KXX73554.1 - 0.047 12.5 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.8 KXX73555.1 - 2.3e-30 105.7 0.0 3.7e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX73555.1 - 0.00014 20.7 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.15 KXX73555.1 - 0.00019 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KXX73555.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX73555.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3966 PF13110.1 KXX73555.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) MFS_1 PF07690.11 KXX73556.1 - 5.8e-06 25.2 20.8 5.5e-05 22.0 5.0 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily Prefoldin_3 PF13758.1 KXX73557.1 - 0.032 13.9 0.1 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit SET PF00856.23 KXX73558.1 - 0.0037 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 SET domain Peroxidase_2 PF01328.12 KXX73559.1 - 1.4e-19 69.9 0.0 1.5e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.3 KXX73560.1 - 5.4e-06 25.2 1.0 7.8e-06 24.7 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.9 KXX73561.1 - 1.5e-63 214.5 0.0 1.8e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mg_trans_NIPA PF05653.9 KXX73562.1 - 7.7e-91 304.1 23.8 1.1e-90 303.6 16.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KXX73562.1 - 2.5e-08 34.1 6.1 2.5e-08 34.1 4.2 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KXX73562.1 - 1.1e-05 25.4 7.9 1.1e-05 25.4 5.5 2.9 2 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 KXX73562.1 - 0.52 9.0 14.1 1.6 7.4 9.0 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Ank_2 PF12796.2 KXX73563.1 - 8.2e-30 102.9 2.8 1.6e-10 41.1 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73563.1 - 4.7e-19 67.1 7.0 0.00049 19.7 0.2 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KXX73563.1 - 6.2e-19 67.5 5.0 0.00046 20.3 0.0 6.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX73563.1 - 4e-17 62.2 5.0 0.00052 20.4 0.0 5.5 4 1 3 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73563.1 - 2.1e-15 55.2 6.3 0.037 14.2 0.0 8.5 9 0 0 9 9 8 4 Ankyrin repeat NACHT PF05729.7 KXX73563.1 - 1.4e-12 47.6 0.0 6e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX73563.1 - 4.6e-08 33.2 0.0 3.9e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX73563.1 - 0.0043 17.2 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain HTH_IclR PF09339.5 KXX73563.1 - 0.012 15.2 0.7 0.095 12.3 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain AAA_14 PF13173.1 KXX73563.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 KXX73563.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.17 KXX73563.1 - 0.19 11.9 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SWIRM PF04433.12 KXX73564.1 - 1.8e-13 50.3 0.0 5.6e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KXX73564.1 - 1.1e-07 31.7 0.1 4.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 KXX73564.1 - 2.1e-05 23.9 3.8 3.8e-05 23.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SHOCT PF09851.4 KXX73564.1 - 0.015 14.7 0.5 0.062 12.7 0.4 2.1 1 0 0 1 1 1 0 Short C-terminal domain adh_short PF00106.20 KXX73565.1 - 3.5e-13 49.8 0.1 7.9e-13 48.6 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73565.1 - 0.00034 20.3 0.5 0.0016 18.1 0.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX73565.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX73565.1 - 0.0046 16.9 0.0 0.082 12.9 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Mucin PF01456.12 KXX73566.1 - 0.14 11.8 21.5 0.21 11.3 14.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1627 PF07789.7 KXX73566.1 - 0.92 9.0 7.0 0.85 9.1 3.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1627) DUF59 PF01883.14 KXX73567.1 - 1.3e-06 28.3 0.0 3.6e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 KXX73568.1 - 7.4e-42 142.9 0.0 1e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KXX73568.1 - 1e-27 96.0 0.0 3.6e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KXX73568.1 - 3.9e-18 65.1 0.0 1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX73568.1 - 3.3e-08 33.5 0.1 8.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KXX73568.1 - 8.2e-07 28.7 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX73568.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX73568.1 - 0.00041 20.8 0.0 0.0013 19.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KXX73568.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras family Thiolase_N PF00108.18 KXX73569.1 - 4e-94 314.4 0.6 4e-94 314.4 0.4 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX73569.1 - 5.1e-46 155.0 0.2 1.4e-45 153.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KXX73569.1 - 0.001 18.6 1.4 0.001 18.6 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KXX73569.1 - 0.43 10.2 3.6 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.27 KXX73570.1 - 5.5e-12 45.0 0.5 0.012 15.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Sel1 PF08238.7 KXX73571.1 - 1.7e-45 152.4 50.7 5.1e-06 26.9 0.1 13.2 12 2 1 13 13 13 10 Sel1 repeat TPR_11 PF13414.1 KXX73571.1 - 0.0015 18.1 0.5 0.0015 18.1 0.4 5.6 5 0 0 5 5 5 1 TPR repeat GRP PF07172.6 KXX73571.1 - 0.022 15.1 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family TPR_6 PF13174.1 KXX73571.1 - 0.11 13.0 0.3 0.11 13.0 0.2 8.7 9 1 0 9 9 9 0 Tetratricopeptide repeat FHIPEP PF00771.15 KXX73571.1 - 0.22 9.8 0.3 0.32 9.2 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family Mei5 PF10376.4 KXX73572.1 - 0.16 11.5 2.8 2.1 7.8 0.0 2.4 1 1 0 2 2 2 0 Double-strand recombination repair protein Fer2_3 PF13085.1 KXX73573.1 - 4.5e-33 113.3 0.0 7.2e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KXX73573.1 - 3e-09 37.0 6.2 3e-09 37.0 4.3 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KXX73573.1 - 3.8e-09 36.4 4.4 3.8e-09 36.4 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KXX73573.1 - 6.2e-05 23.3 1.3 6.2e-05 23.3 0.9 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KXX73573.1 - 0.00015 21.4 3.7 0.00015 21.4 2.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KXX73573.1 - 0.00021 21.5 4.1 0.031 14.5 0.5 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KXX73573.1 - 0.0033 17.1 0.2 0.0033 17.1 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KXX73573.1 - 0.027 14.8 5.8 0.027 14.8 4.0 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KXX73573.1 - 0.045 14.1 1.0 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KXX73573.1 - 1.2 9.8 5.4 0.98 10.0 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Hist_deacetyl PF00850.14 KXX73575.1 - 6e-79 265.5 0.5 7.1e-79 265.3 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain RCC1 PF00415.13 KXX73576.1 - 1.2e-22 79.7 0.1 3.8e-07 30.2 0.1 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KXX73576.1 - 6e-10 39.3 0.1 1.4e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BTB PF00651.26 KXX73576.1 - 9.1e-09 35.2 0.0 3.2e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KXX73576.1 - 6.7e-08 31.9 6.7 7.5e-07 28.6 0.8 4.0 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KXX73576.1 - 7.1e-08 31.9 0.2 0.024 14.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KXX73576.1 - 4.1e-05 23.8 0.2 0.00012 22.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73576.1 - 0.0071 16.1 0.1 0.057 13.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KXX73576.1 - 0.037 14.2 0.1 0.24 11.7 0.0 2.5 1 1 0 1 1 1 0 Ankyrin repeats (many copies) ATG13 PF10033.4 KXX73577.1 - 1.4e-72 243.9 0.0 2.7e-72 242.9 0.0 1.5 2 0 0 2 2 2 1 Autophagy-related protein 13 UDPGP PF01704.13 KXX73578.1 - 1.3e-184 613.6 0.1 1.5e-184 613.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ING PF12998.2 KXX73579.1 - 3.3e-24 85.1 7.4 5e-24 84.5 5.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KXX73579.1 - 1.3e-07 31.2 9.0 2e-07 30.5 6.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KXX73579.1 - 0.027 14.6 0.2 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1704 PF08014.6 KXX73579.1 - 0.027 13.4 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Mod_r PF07200.8 KXX73579.1 - 0.061 13.2 1.2 0.22 11.4 0.8 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.3 KXX73579.1 - 0.22 8.8 5.0 0.29 8.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 KXX73579.1 - 0.33 10.5 4.5 0.5 9.9 3.1 1.2 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 KXX73579.1 - 2 7.9 4.9 16 5.0 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KXX73579.1 - 3.9 7.0 8.0 12 5.4 5.5 1.7 1 1 0 1 1 1 0 IncA protein Mito_carr PF00153.22 KXX73580.1 - 8.8e-68 224.0 4.4 1.3e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KXX73580.1 - 0.39 10.7 3.4 0.42 10.6 0.1 2.8 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family zf-C3HC4_3 PF13920.1 KXX73581.1 - 0.0038 16.8 11.2 0.0062 16.1 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KXX73581.1 - 0.028 14.2 6.1 0.044 13.5 4.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KXX73581.1 - 1.6 8.5 12.7 2.5 7.9 8.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FA_hydroxylase PF04116.8 KXX73582.1 - 9.7e-15 54.9 14.5 9.7e-15 54.9 10.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4519 PF15012.1 KXX73582.1 - 0.079 12.8 0.5 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Dor1 PF04124.7 KXX73582.1 - 0.11 10.9 0.1 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family DAGK_cat PF00781.19 KXX73584.1 - 0.088 12.2 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PPR_2 PF13041.1 KXX73586.1 - 2.8e-28 97.6 0.0 3.7e-07 30.0 0.0 7.0 5 1 1 6 6 6 6 PPR repeat family PPR_3 PF13812.1 KXX73586.1 - 2.8e-21 73.9 0.3 0.0033 17.5 0.0 8.4 8 0 0 8 8 8 6 Pentatricopeptide repeat domain PPR PF01535.15 KXX73586.1 - 9.2e-18 62.9 0.0 0.011 15.6 0.0 6.5 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 KXX73586.1 - 1.9e-12 46.4 0.4 0.0044 16.4 0.0 5.5 5 0 0 5 5 5 3 PPR repeat ECSIT PF06239.6 KXX73586.1 - 0.21 10.4 0.0 7.9 5.2 0.0 2.8 2 1 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Septin PF00735.13 KXX73587.1 - 3.7e-16 58.9 0.0 6.1e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KXX73587.1 - 7.1e-06 25.9 0.0 2.3e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX73587.1 - 0.00031 21.2 0.4 0.0013 19.1 0.1 2.2 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KXX73587.1 - 0.002 18.3 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KXX73587.1 - 0.002 17.3 0.1 0.0091 15.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX73587.1 - 0.0077 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KXX73587.1 - 0.0086 15.5 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 KXX73587.1 - 0.0094 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KXX73587.1 - 0.012 15.0 0.1 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX73587.1 - 0.02 15.0 0.1 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KXX73587.1 - 0.025 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 KXX73587.1 - 0.027 13.4 0.3 0.075 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KXX73587.1 - 0.039 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MCM PF00493.18 KXX73587.1 - 0.039 12.7 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Gtr1_RagA PF04670.7 KXX73587.1 - 0.04 13.0 0.2 2.9 6.9 0.0 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 KXX73587.1 - 0.056 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 KXX73587.1 - 0.07 12.7 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.8 KXX73587.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus GTP_EFTU PF00009.22 KXX73587.1 - 0.097 12.0 0.0 0.46 9.8 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KXX73587.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KXX73587.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KXX73587.1 - 0.13 12.1 0.5 1 9.1 0.1 2.3 2 1 0 2 2 1 0 Dynamin family Sigma54_activat PF00158.21 KXX73587.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 KXX73587.1 - 0.17 12.7 0.1 0.32 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KXX73587.1 - 0.2 11.3 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Ras PF00071.17 KXX73587.1 - 0.26 10.6 0.2 0.56 9.5 0.1 1.5 2 0 0 2 2 1 0 Ras family DUF3435 PF11917.3 KXX73588.1 - 3.8e-76 256.4 0.1 4.7e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Lipoprotein_21 PF14041.1 KXX73588.1 - 0.16 11.9 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 LppP/LprE lipoprotein WD40 PF00400.27 KXX73590.1 - 4.9e-28 95.9 1.5 4.6e-14 51.6 0.2 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 KXX73592.1 - 1.7e-13 50.5 1.3 5.3e-07 29.4 0.1 2.5 1 1 1 2 2 2 2 NACHT domain Mlp PF03304.8 KXX73592.1 - 0.0036 17.3 0.2 0.0089 16.0 0.0 1.7 2 0 0 2 2 2 1 Mlp lipoprotein family AAA_19 PF13245.1 KXX73592.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KXX73592.1 - 0.44 10.5 2.4 3.5 7.5 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain BUD22 PF09073.5 KXX73593.1 - 0.76 8.7 16.5 1.1 8.2 11.4 1.2 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.8 KXX73593.1 - 2.6 5.7 36.2 0.033 12.0 9.9 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Nucleoplasmin PF03066.10 KXX73593.1 - 8.2 5.9 9.6 3.3 7.2 0.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin RRM_1 PF00076.17 KXX73594.1 - 2.3e-10 39.9 0.1 4.4e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX73594.1 - 1.2e-09 37.9 0.0 2.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX73594.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX73594.1 - 0.00025 20.7 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif p450 PF00067.17 KXX73595.1 - 3.8e-47 160.8 0.0 5.2e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.27 KXX73596.1 - 6.3e-21 72.0 6.2 4e-07 28.8 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KXX73596.1 - 3.4e-20 71.9 0.7 3.9e-12 46.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KXX73596.1 - 1e-18 65.4 5.6 4.7e-07 29.1 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KXX73596.1 - 3.5e-17 61.7 5.9 1.5e-10 40.5 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KXX73596.1 - 1.4e-11 43.1 8.6 5.8e-05 22.2 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KXX73596.1 - 2.3e-05 24.2 0.0 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 KXX73596.1 - 0.017 14.6 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.2 KXX73596.1 - 0.023 14.4 0.1 0.61 9.8 0.0 2.3 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 KXX73596.1 - 0.024 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_like PF09279.6 KXX73596.1 - 0.095 12.7 0.1 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Nnf1 PF03980.9 KXX73597.1 - 0.041 13.8 1.7 0.069 13.1 0.2 1.9 2 0 0 2 2 2 0 Nnf1 PV-1 PF06637.6 KXX73597.1 - 0.071 11.6 1.7 0.13 10.7 1.2 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DivIC PF04977.10 KXX73597.1 - 1.4 8.4 5.9 0.11 12.0 0.6 1.6 2 0 0 2 2 2 0 Septum formation initiator BUD22 PF09073.5 KXX73600.1 - 2.8e-74 250.7 34.9 9.9e-48 163.2 12.7 2.0 1 1 1 2 2 2 2 BUD22 Polysacc_synt_3 PF13440.1 KXX73601.1 - 0.053 12.9 0.5 0.082 12.3 0.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UPF0118 PF01594.11 KXX73601.1 - 0.29 10.0 2.9 0.43 9.5 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 ABC2_membrane PF01061.19 KXX73602.1 - 4.4e-81 271.0 53.2 1.4e-42 145.2 13.1 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KXX73602.1 - 9.5e-39 132.8 0.0 2.8e-18 66.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KXX73602.1 - 3e-25 87.8 1.7 1.7e-22 78.9 0.0 3.1 3 0 0 3 3 2 1 CDR ABC transporter ABC_trans_N PF14510.1 KXX73602.1 - 2.6e-11 43.4 0.0 9.4e-11 41.6 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KXX73602.1 - 2.6e-07 30.6 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX73602.1 - 5.7e-06 25.8 0.2 0.004 16.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 KXX73602.1 - 1.6e-05 24.9 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KXX73602.1 - 2.6e-05 23.4 37.2 0.0028 16.7 9.3 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 KXX73602.1 - 3.3e-05 24.0 0.0 0.23 11.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KXX73602.1 - 6.7e-05 22.9 0.1 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KXX73602.1 - 7.2e-05 22.2 0.5 0.0048 16.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KXX73602.1 - 9.2e-05 21.9 2.8 0.0082 15.6 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KXX73602.1 - 0.0001 23.0 0.0 0.0083 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KXX73602.1 - 0.00019 21.0 2.3 0.55 9.8 0.1 3.0 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KXX73602.1 - 0.00045 19.4 0.0 0.005 16.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KXX73602.1 - 0.0007 19.5 0.2 0.034 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX73602.1 - 0.00079 19.1 0.4 0.96 9.2 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 KXX73602.1 - 0.0029 17.9 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KXX73602.1 - 0.003 17.2 1.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KXX73602.1 - 0.0039 16.4 0.0 0.71 9.0 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 KXX73602.1 - 0.02 14.4 0.2 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KXX73602.1 - 0.043 13.2 0.3 3.3 7.0 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain ATP-synt_ab PF00006.20 KXX73602.1 - 0.051 13.0 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 KXX73602.1 - 0.063 13.7 0.0 7.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KXX73602.1 - 0.065 12.8 0.1 7.7 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KXX73602.1 - 0.083 13.0 0.3 13 6.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KXX73602.1 - 0.087 12.3 0.4 5 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KXX73602.1 - 0.11 11.9 1.0 2.3 7.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KXX73602.1 - 0.16 12.2 0.7 0.44 10.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.1 KXX73602.1 - 0.39 9.7 0.0 2.4 7.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.24 KXX73603.1 - 4.4e-30 104.3 0.0 4.2e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX73603.1 - 3.5e-21 74.8 0.1 7.1e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX73603.1 - 1.4e-05 24.9 0.2 9.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSP70 PF00012.15 KXX73604.1 - 6.6e-13 47.4 0.0 1.2e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 KXX73604.1 - 0.002 17.4 0.4 0.0063 15.8 0.0 2.0 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family DUF1693 PF07984.7 KXX73604.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) Peptidase_M22 PF00814.20 KXX73604.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 1 0 1 1 1 0 Glycoprotease family Tropomyosin PF00261.15 KXX73605.1 - 7.9e-05 21.8 1.5 7.9e-05 21.8 1.1 1.8 2 0 0 2 2 2 1 Tropomyosin Atg14 PF10186.4 KXX73605.1 - 0.18 10.6 2.3 0.31 9.9 1.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 KXX73606.1 - 0.0035 17.6 0.2 0.0082 16.4 0.1 1.7 1 0 0 1 1 1 1 SlyX Filament PF00038.16 KXX73606.1 - 0.0068 15.9 0.6 0.009 15.5 0.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein CENP-Q PF13094.1 KXX73606.1 - 0.018 15.1 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Spc34 PF08657.5 KXX73606.1 - 0.018 14.6 0.2 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 ATG16 PF08614.6 KXX73606.1 - 0.023 14.5 1.4 0.049 13.4 1.0 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 KXX73606.1 - 0.028 14.0 0.2 0.041 13.5 0.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF16 PF01519.11 KXX73606.1 - 0.04 14.1 1.1 0.059 13.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.6 KXX73606.1 - 0.059 12.0 2.2 0.076 11.6 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KXX73606.1 - 0.065 12.8 0.7 0.094 12.2 0.5 1.2 1 0 0 1 1 1 0 IncA protein Cluap1 PF10234.4 KXX73606.1 - 0.069 12.3 1.1 0.092 11.9 0.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 NPV_P10 PF05531.7 KXX73606.1 - 0.071 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.7 KXX73606.1 - 0.13 11.5 0.9 0.2 10.9 0.6 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus USP8_interact PF08941.5 KXX73606.1 - 0.14 11.4 0.4 0.21 10.9 0.3 1.2 1 0 0 1 1 1 0 USP8 interacting DivIC PF04977.10 KXX73606.1 - 0.18 11.3 4.4 0.62 9.5 3.1 1.7 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 KXX73606.1 - 0.28 11.0 5.8 0.48 10.2 4.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 KXX73606.1 - 2.4 7.9 6.1 20 4.9 0.6 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF605 PF04652.11 KXX73606.1 - 5.3 6.3 11.9 6.3 6.0 8.3 1.1 1 0 0 1 1 1 0 Vta1 like HSP70 PF00012.15 KXX73607.1 - 1.9e-56 191.2 21.6 6.7e-52 176.2 0.0 3.7 3 1 0 3 3 3 2 Hsp70 protein IBR PF01485.16 KXX73608.1 - 1.3e-12 47.4 20.0 1.7e-11 43.8 1.7 3.6 3 1 0 3 3 3 2 IBR domain PRP21_like_P PF12230.3 KXX73608.1 - 0.0078 15.7 8.5 0.018 14.5 5.9 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zinc-ribbons_6 PF07191.7 KXX73608.1 - 0.0078 15.9 1.1 4.6 7.0 0.1 2.8 2 0 0 2 2 2 2 zinc-ribbons zf-ribbon_3 PF13248.1 KXX73608.1 - 0.035 13.3 4.1 5.6 6.3 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain SRP-alpha_N PF04086.8 KXX73608.1 - 0.052 12.9 10.3 0.095 12.0 7.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zinc_ribbon_2 PF13240.1 KXX73608.1 - 0.086 12.3 1.8 2.6 7.6 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Cas_Csm6 PF09659.5 KXX73608.1 - 0.087 11.4 2.2 0.14 10.7 1.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) Med19 PF10278.4 KXX73608.1 - 1.2 8.8 10.2 2 8.0 7.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 UPF0547 PF10571.4 KXX73608.1 - 1.6 8.5 9.0 2.6 7.8 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF1510 PF07423.6 KXX73608.1 - 2.2 7.5 10.9 3.5 6.9 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1682 PF07946.9 KXX73608.1 - 3 6.5 17.2 4.7 5.9 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4551 PF15087.1 KXX73608.1 - 7.4 4.8 8.1 13 4.0 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Bromodomain PF00439.20 KXX73609.1 - 2e-13 50.0 0.0 5.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain SH3_1 PF00018.23 KXX73610.1 - 8.7e-38 127.4 5.7 3.1e-13 48.8 0.3 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KXX73610.1 - 1.6e-36 123.7 0.0 2.8e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KXX73610.1 - 2.8e-36 122.8 6.2 2.4e-13 49.4 0.2 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.12 KXX73610.1 - 1e-25 88.9 0.3 2.7e-08 33.1 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KXX73610.1 - 1.3e-07 31.6 4.6 0.22 11.7 0.6 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain DUF1720 PF08226.6 KXX73610.1 - 0.00021 21.2 25.2 0.00021 21.2 17.5 6.6 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) Polysacc_deac_1 PF01522.16 KXX73611.1 - 6.2e-23 80.7 0.0 8.5e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase TRAM_LAG1_CLN8 PF03798.11 KXX73612.1 - 4.7e-50 169.8 14.1 4.7e-50 169.8 9.8 1.4 2 0 0 2 2 2 1 TLC domain A_deaminase PF00962.17 KXX73614.1 - 2.5e-109 365.1 0.2 3.4e-109 364.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 KXX73614.1 - 2.2e-87 292.7 12.6 1.8e-86 289.7 8.8 2.0 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KXX73614.1 - 0.00012 21.2 0.3 0.00028 20.0 0.2 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KXX73614.1 - 0.00091 18.9 2.7 0.00091 18.9 1.9 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 KXX73614.1 - 0.14 12.3 15.9 0.13 12.4 0.8 3.0 2 1 1 3 3 3 0 Multidrug resistance efflux transporter ABC_membrane PF00664.18 KXX73615.1 - 1.3e-19 70.7 1.8 1.3e-19 70.7 1.3 2.5 2 1 0 2 2 2 1 ABC transporter transmembrane region YukC PF10140.4 KXX73615.1 - 0.23 9.9 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RTA1 PF04479.8 KXX73616.1 - 3.7e-40 137.8 11.9 7.9e-40 136.7 5.1 2.0 1 1 1 2 2 2 2 RTA1 like protein TPR_12 PF13424.1 KXX73617.1 - 3.4e-47 158.2 13.2 1.2e-18 66.7 0.5 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KXX73617.1 - 3.5e-37 125.2 11.6 1.6e-11 43.7 0.0 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat Clr5 PF14420.1 KXX73617.1 - 4e-15 55.4 0.1 1.1e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Clr5 domain TPR_11 PF13414.1 KXX73617.1 - 4.7e-08 32.5 0.6 0.0041 16.7 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 KXX73617.1 - 1.3e-07 32.1 1.0 0.0027 18.3 0.2 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX73617.1 - 6.2e-06 25.5 3.1 0.066 12.8 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73617.1 - 3.6e-05 23.6 0.3 1.5 9.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73617.1 - 7.2e-05 22.2 3.5 0.054 13.3 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX73617.1 - 0.00014 21.4 7.2 0.21 11.5 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 KXX73617.1 - 0.0018 18.0 3.2 2.3 8.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX73617.1 - 0.003 17.8 2.9 0.017 15.4 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX73617.1 - 0.0034 17.4 1.5 0.063 13.4 0.1 2.7 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KXX73617.1 - 0.0075 16.5 5.7 0.11 12.9 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat YebF PF13995.1 KXX73617.1 - 0.12 12.4 0.2 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 YebF-like protein TPR_14 PF13428.1 KXX73617.1 - 0.33 11.7 4.8 2.4 9.0 0.1 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KXX73617.1 - 0.52 10.2 3.0 1.2 9.0 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat VWA_3 PF13768.1 KXX73618.1 - 7.9e-29 100.3 0.0 1.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KXX73618.1 - 4.7e-20 71.4 0.0 1.3e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KXX73618.1 - 5.1e-14 52.7 0.0 9.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KXX73618.1 - 6.1e-09 35.2 0.0 1.8e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KXX73618.1 - 1.1e-07 31.7 0.1 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KXX73618.1 - 0.0016 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 KXX73618.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DM PF00751.13 KXX73620.1 - 1.2 8.7 6.2 0.23 11.0 1.0 2.1 2 0 0 2 2 2 0 DM DNA binding domain PHO4 PF01384.15 KXX73621.1 - 0.051 12.2 1.3 0.071 11.7 0.9 1.1 1 0 0 1 1 1 0 Phosphate transporter family HET PF06985.6 KXX73622.1 - 3.2e-08 33.8 0.0 2.3e-06 27.8 0.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-CHCC PF10276.4 KXX73624.1 - 8.7e-17 60.6 1.1 1.3e-16 60.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KXX73624.1 - 0.0085 15.7 0.3 0.015 14.9 0.2 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb Pol_alpha_B_N PF08418.5 KXX73624.1 - 2 7.8 5.4 2.5 7.5 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-CCHC PF00098.18 KXX73625.1 - 0.00013 21.6 3.4 0.00021 21.0 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KXX73625.1 - 0.016 14.7 0.9 0.029 13.8 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle MelC1 PF06236.6 KXX73625.1 - 8.6 6.3 10.5 6.9 6.6 3.5 2.3 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Peptidase_M16_C PF05193.16 KXX73626.1 - 1e-32 113.3 0.1 3.7e-17 62.5 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KXX73626.1 - 5e-28 97.7 1.2 2.5e-27 95.4 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HEAT PF02985.17 KXX73627.1 - 3.2e-44 145.0 12.3 0.0087 16.0 0.0 12.9 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 KXX73627.1 - 1.2e-28 99.2 3.2 1e-06 28.9 0.0 7.6 3 3 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 KXX73627.1 - 7.9e-12 45.4 4.1 0.04 14.3 0.0 7.6 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KXX73627.1 - 1.1e-10 41.6 11.1 0.031 14.7 0.0 8.8 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KXX73627.1 - 9.3e-09 34.1 5.1 0.00023 19.6 0.1 4.4 3 1 2 5 5 5 3 Adaptin N terminal region CLASP_N PF12348.3 KXX73627.1 - 3.4e-05 23.3 1.7 1.9 7.7 0.0 4.7 3 3 2 5 5 5 2 CLASP N terminal Arm PF00514.18 KXX73627.1 - 0.0006 19.5 1.8 1.4 8.8 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 KXX73627.1 - 0.00081 19.2 3.7 0.022 14.6 0.2 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KXX73627.1 - 0.022 14.6 4.9 1.5 8.6 0.1 4.8 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 KXX73627.1 - 0.049 12.6 0.7 0.38 9.7 0.1 2.5 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Methyltransf_18 PF12847.2 KXX73629.1 - 6.9e-18 65.2 0.3 1.4e-17 64.3 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX73629.1 - 1.2e-15 57.4 0.0 3.1e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX73629.1 - 2.8e-10 40.2 0.6 1.4e-09 37.9 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX73629.1 - 2.3e-07 31.1 0.0 1.5e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX73629.1 - 4e-07 30.4 0.0 1.5e-05 25.3 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX73629.1 - 7.1e-07 29.0 0.0 3.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX73629.1 - 6.4e-06 26.5 0.0 2.8e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KXX73629.1 - 1.1e-05 24.8 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KXX73629.1 - 4.3e-05 22.7 0.0 0.00022 20.4 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX73629.1 - 8.1e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KXX73629.1 - 0.00049 19.8 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX73629.1 - 0.0025 16.9 0.0 0.79 8.7 0.0 2.1 1 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KXX73629.1 - 0.0026 17.7 0.0 0.0034 17.3 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KXX73629.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.11 KXX73629.1 - 0.015 14.1 0.0 0.96 8.2 0.0 2.4 3 0 0 3 3 3 0 mRNA capping enzyme AdoMet_MTase PF07757.8 KXX73629.1 - 0.052 13.6 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.12 KXX73629.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 KXX73629.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SEP PF08059.8 KXX73630.1 - 1e-25 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 KXX73630.1 - 9.4e-13 47.4 0.5 1.5e-12 46.7 0.4 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KXX73630.1 - 1.9e-09 37.4 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain Lipoprotein_19 PF13617.1 KXX73630.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein TOM13 PF08219.6 KXX73631.1 - 2.5e-28 97.6 0.0 3.3e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 KXX73632.1 - 7.5e-34 117.1 1.4 7.5e-34 117.1 1.0 1.4 2 0 0 2 2 2 1 60Kd inner membrane protein Pro_CA PF00484.14 KXX73633.1 - 2.2e-05 24.5 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.11 KXX73634.1 - 6.8e-41 140.1 44.4 1.7e-40 138.8 30.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73634.1 - 6.8e-14 51.2 26.7 7.7e-13 47.8 11.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Ank_2 PF12796.2 KXX73635.1 - 4.4e-55 183.9 14.1 1.3e-14 54.2 0.0 11.0 6 3 4 11 11 11 9 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73635.1 - 6e-34 114.1 24.4 2.6e-05 23.7 0.0 15.7 18 1 0 18 18 18 8 Ankyrin repeat Ank_4 PF13637.1 KXX73635.1 - 4.2e-27 94.0 17.0 2.3e-06 27.9 0.0 11.5 10 2 2 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73635.1 - 6.3e-27 90.9 15.8 0.0064 16.6 0.0 15.7 18 0 0 18 18 18 5 Ankyrin repeat Ank_5 PF13857.1 KXX73635.1 - 2.2e-20 72.2 7.6 1.9e-06 27.9 0.0 9.0 8 1 2 10 10 10 4 Ankyrin repeats (many copies) pRN1_helical PF13010.1 KXX73635.1 - 0.11 12.0 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Primase helical domain Nodulin-like PF06813.8 KXX73635.1 - 0.26 10.5 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Nodulin-like Zn_clus PF00172.13 KXX73636.1 - 4.7e-08 32.8 7.3 8.3e-08 32.0 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.13 KXX73636.1 - 0.07 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain PBP PF01161.15 KXX73637.1 - 1e-26 93.5 0.2 1.6e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.9 KXX73638.1 - 8.1e-147 488.9 1.7 9.6e-147 488.6 1.2 1.1 1 0 0 1 1 1 1 Erythromycin esterase Gtr1_RagA PF04670.7 KXX73639.1 - 2.6e-96 321.2 0.0 3.3e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KXX73639.1 - 5.6e-09 35.4 0.1 8.6e-09 34.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KXX73639.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KXX73639.1 - 2.7e-05 24.0 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX73639.1 - 9.9e-05 22.8 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KXX73639.1 - 0.0011 18.4 0.3 0.0089 15.5 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KXX73639.1 - 0.0078 16.5 0.1 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KXX73639.1 - 0.0078 15.4 0.1 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 KXX73639.1 - 0.0078 14.9 0.2 0.076 11.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit DUF815 PF05673.8 KXX73639.1 - 0.01 14.8 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KXX73639.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Serglycin PF04360.7 KXX73640.1 - 5.8 6.6 7.7 12 5.5 5.3 1.6 1 0 0 1 1 1 0 Serglycin LRR_4 PF12799.2 KXX73641.1 - 5.6e-39 131.1 41.1 2.1e-08 33.5 4.5 10.1 7 2 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX73641.1 - 6.7e-32 109.0 43.1 8.9e-08 31.7 5.1 9.8 5 2 6 13 13 13 10 Leucine rich repeat LRR_1 PF00560.28 KXX73641.1 - 8.7e-22 73.8 38.4 0.0018 18.0 1.4 15.6 15 2 0 15 15 15 7 Leucine Rich Repeat LRR_7 PF13504.1 KXX73641.1 - 1.2e-11 42.7 43.2 0.74 10.2 0.0 14.0 13 1 1 14 14 14 7 Leucine rich repeat LRR_6 PF13516.1 KXX73641.1 - 2.2e-07 30.2 44.2 0.69 10.1 0.0 13.4 14 1 1 15 15 15 3 Leucine Rich repeat LRR_9 PF14580.1 KXX73641.1 - 0.0023 17.5 9.5 5 6.6 0.0 4.6 2 2 3 5 5 5 4 Leucine-rich repeat DPM3 PF08285.6 KXX73642.1 - 5.7e-33 112.6 0.4 6.3e-33 112.4 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pribosyltran PF00156.22 KXX73643.1 - 3.8e-10 39.5 0.1 8.1e-10 38.4 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 KXX73644.1 - 1.3e-25 88.5 3.1 1.3e-25 88.5 2.1 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal CDC27 PF09507.5 KXX73644.1 - 0.0066 15.7 12.2 0.0078 15.4 8.4 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SRP-alpha_N PF04086.8 KXX73644.1 - 1.2 8.4 13.1 14 4.9 8.6 2.2 2 1 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal FNIP_N PF14636.1 KXX73644.1 - 1.3 9.5 12.7 0.2 12.0 4.2 2.2 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus Mitofilin PF09731.4 KXX73644.1 - 2.6 6.6 13.2 3.4 6.1 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tmemb_cc2 PF10267.4 KXX73644.1 - 4 5.9 4.5 5.9 5.3 3.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DAHP_synth_1 PF00793.15 KXX73646.1 - 3.1e-101 337.6 0.1 3.6e-101 337.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mito_fiss_reg PF05308.6 KXX73647.1 - 1.2 8.4 6.4 1.7 7.9 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Zn_clus PF00172.13 KXX73648.1 - 0.019 14.8 14.2 0.038 13.8 9.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KXX73649.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PalH PF08733.5 KXX73650.1 - 0.088 11.6 0.1 0.088 11.6 0.1 1.9 2 0 0 2 2 2 0 PalH/RIM21 7TMR-DISM_7TM PF07695.6 KXX73650.1 - 0.21 11.2 15.2 0.11 12.1 8.9 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling Thiolase_C PF02803.13 KXX73651.1 - 5.2e-10 38.8 1.5 8.8e-10 38.0 0.2 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KXX73651.1 - 1.7e-06 27.5 1.1 2.4e-05 23.9 0.1 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KXX73651.1 - 4.3e-06 25.9 0.6 5.6e-05 22.2 0.0 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KXX73651.1 - 0.0049 16.3 0.3 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KXX73651.1 - 0.0067 14.9 0.6 0.14 10.5 0.1 2.4 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 KXX73651.1 - 0.061 13.1 0.1 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain MRP-S25 PF13741.1 KXX73652.1 - 5.5e-30 104.5 4.2 2.6e-28 99.0 2.9 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 KXX73653.1 - 6.8e-18 64.3 0.1 5.4e-07 29.4 0.0 5.4 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KXX73653.1 - 7.8e-13 47.6 5.9 0.032 14.5 0.0 6.5 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 KXX73653.1 - 2.3e-12 46.0 13.4 0.0012 18.6 0.0 7.3 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 KXX73653.1 - 0.00018 20.9 0.2 11 5.5 0.0 4.4 4 0 0 4 4 4 2 PPR repeat Ald_Xan_dh_C2 PF02738.13 KXX73654.1 - 1.4e-191 637.5 0.2 1.9e-191 637.1 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KXX73654.1 - 1.8e-51 174.0 0.0 3.1e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KXX73654.1 - 5.8e-32 109.7 1.9 1.1e-30 105.5 0.0 3.0 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KXX73654.1 - 1.2e-30 105.8 0.0 2.9e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KXX73654.1 - 8.8e-29 99.2 0.1 1.8e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KXX73654.1 - 3e-08 33.3 2.1 4.1e-08 32.8 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Aldedh PF00171.17 KXX73656.1 - 5.2e-140 466.8 0.0 6.1e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX73656.1 - 2.2e-06 26.6 0.1 0.033 12.9 0.0 2.0 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) HET PF06985.6 KXX73658.1 - 5.5e-16 58.9 0.0 8.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Metallophos_2 PF12850.2 KXX73659.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX73659.1 - 1e-08 34.8 0.5 2.8e-07 30.1 0.3 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.17 KXX73661.1 - 4.1e-51 173.9 0.1 4.9e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 KXX73662.1 - 0.013 15.7 1.4 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KXX73662.1 - 0.018 15.2 2.3 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PLA1 PF02253.10 KXX73662.1 - 0.068 12.5 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A1 zf-C2H2_jaz PF12171.3 KXX73662.1 - 0.25 11.5 1.4 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KXX73662.1 - 2.2 8.0 4.1 2.1 8.1 1.5 2.0 2 0 0 2 2 2 0 BED zinc finger Pro_CA PF00484.14 KXX73663.1 - 2.2e-05 24.4 0.4 2.7e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ACP PF06857.6 KXX73663.1 - 0.062 13.2 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) GMC_oxred_N PF00732.14 KXX73664.1 - 3.1e-28 98.7 0.0 5.3e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX73664.1 - 1.2e-22 80.7 0.1 2.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX73664.1 - 1e-08 34.4 0.1 0.00041 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX73664.1 - 1.4e-07 30.7 0.2 4.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX73664.1 - 2.4e-05 24.2 0.7 0.00013 21.9 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX73664.1 - 0.0004 20.3 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX73664.1 - 0.011 14.8 0.1 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KXX73664.1 - 0.013 14.0 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KXX73664.1 - 0.013 15.5 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX73664.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KXX73664.1 - 0.048 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pho88 PF10032.4 KXX73665.1 - 7.7e-78 260.1 0.0 8.6e-78 259.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Asp PF00026.18 KXX73666.1 - 1.6e-75 254.3 3.2 1.9e-75 254.0 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX73666.1 - 2.3e-08 34.1 0.1 8.8e-07 29.0 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KXX73666.1 - 0.00088 19.7 0.2 0.053 14.0 0.0 3.1 2 2 0 2 2 2 1 Aspartyl protease PTR2 PF00854.16 KXX73667.1 - 1.2e-21 76.9 8.3 4.2e-11 42.2 1.2 2.5 3 0 0 3 3 3 2 POT family XPA_C PF05181.7 KXX73668.1 - 2.2e-29 100.7 4.2 4.3e-29 99.8 2.9 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KXX73668.1 - 0.017 14.7 4.2 0.017 14.7 2.9 1.9 2 0 0 2 2 2 0 XPA protein N-terminal ArfGap PF01412.13 KXX73668.1 - 0.39 10.5 4.5 0.12 12.1 0.5 2.1 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.7 KXX73669.1 - 6.6e-37 126.8 2.9 6.6e-37 126.8 2.0 1.6 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KXX73669.1 - 4.9e-32 108.6 14.9 1.1e-07 31.4 0.0 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat FAR1 PF03101.10 KXX73670.1 - 4.7e-07 30.2 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF1319 PF07028.6 KXX73670.1 - 0.015 15.5 1.2 0.015 15.5 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) Ribosomal_60s PF00428.14 KXX73670.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Clr5 PF14420.1 KXX73671.1 - 2.9e-09 36.6 2.1 5.4e-09 35.8 1.5 1.4 1 0 0 1 1 1 1 Clr5 domain DHC_N1 PF08385.7 KXX73672.1 - 9.5e-193 641.7 1.4 9.5e-193 641.7 1.0 4.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KXX73672.1 - 1e-129 432.6 7.2 1e-129 432.6 5.0 5.2 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KXX73672.1 - 2e-104 350.1 0.0 5.3e-104 348.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KXX73672.1 - 9e-78 260.9 0.0 2.5e-77 259.5 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KXX73672.1 - 1.8e-42 144.7 0.1 6.1e-42 143.0 0.0 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KXX73672.1 - 8.9e-41 139.6 0.6 1.5e-39 135.5 0.1 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 KXX73672.1 - 3.3e-39 134.6 9.5 3.3e-39 134.6 6.6 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KXX73672.1 - 4e-32 110.8 0.0 1.4e-11 44.2 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KXX73672.1 - 1.8e-21 76.4 0.0 1.2e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KXX73672.1 - 5e-15 55.7 0.1 0.017 15.2 0.0 6.2 6 0 0 6 6 4 3 AAA domain AAA PF00004.24 KXX73672.1 - 2.8e-13 50.2 0.0 0.0019 18.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KXX73672.1 - 1.8e-10 40.8 0.2 0.23 11.3 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KXX73672.1 - 3.3e-10 40.8 0.1 0.03 15.1 0.0 6.0 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 KXX73672.1 - 3.6e-09 37.0 1.8 0.022 15.0 0.0 6.0 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.1 KXX73672.1 - 3.4e-07 30.2 0.0 0.21 11.4 0.0 5.8 5 0 0 5 5 5 1 AAA domain T2SE PF00437.15 KXX73672.1 - 9.7e-07 27.9 0.0 0.034 13.0 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 KXX73672.1 - 2e-06 27.1 0.0 0.3 10.6 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 KXX73672.1 - 1.2e-05 24.9 0.2 0.89 9.3 0.0 5.0 5 0 0 5 5 5 1 Part of AAA domain AAA_16 PF13191.1 KXX73672.1 - 1.5e-05 25.1 23.1 0.11 12.4 0.0 9.2 9 1 1 10 10 9 2 AAA ATPase domain Mg_chelatase PF01078.16 KXX73672.1 - 2.4e-05 23.5 0.9 0.5 9.4 0.0 4.2 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KXX73672.1 - 0.00018 21.8 0.1 3.8 7.8 0.0 4.6 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 KXX73672.1 - 0.0013 17.8 4.6 0.97 8.4 0.0 4.2 4 0 0 4 4 3 2 Zeta toxin RNA_helicase PF00910.17 KXX73672.1 - 0.012 15.7 0.1 34 4.6 0.0 4.5 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 KXX73672.1 - 0.042 13.5 0.1 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KXX73672.1 - 0.053 12.9 4.5 0.31 10.4 0.0 4.0 5 0 0 5 5 3 0 AAA domain Phage_Coat_B PF05356.6 KXX73672.1 - 0.36 10.5 0.0 0.88 9.3 0.0 1.7 1 0 0 1 1 1 0 Phage Coat protein B ERM PF00769.14 KXX73672.1 - 4.3 6.7 28.9 5.4 6.4 3.2 3.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1774 PF08611.5 KXX73673.1 - 1.2e-31 108.7 5.8 1.2e-31 108.7 4.0 2.6 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Exo_endo_phos PF03372.18 KXX73674.1 - 1.3e-08 35.0 0.1 1.6e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KXX73674.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase SPRY PF00622.23 KXX73677.1 - 2.2e-19 69.7 0.0 3.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Atrophin-1 PF03154.10 KXX73678.1 - 0.0011 17.2 1.8 0.0011 17.2 1.2 2.1 2 1 0 2 2 2 1 Atrophin-1 family DUF2956 PF11169.3 KXX73678.1 - 2.4 8.1 13.2 2.5 8.1 4.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) Kinesin PF00225.18 KXX73681.1 - 3.6e-111 371.0 0.2 4e-110 367.6 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 KXX73681.1 - 4.1e-46 156.1 0.0 1e-45 154.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 KXX73681.1 - 1.7e-06 27.9 0.4 5e-06 26.4 0.3 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KXX73681.1 - 7e-06 26.0 0.0 5e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 FHA domain PH PF00169.24 KXX73681.1 - 0.0076 16.4 0.0 0.07 13.3 0.0 2.5 1 1 0 1 1 1 1 PH domain Peptidase_M1 PF01433.15 KXX73682.1 - 1.1e-73 248.5 0.0 1.5e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KXX73682.1 - 2.3e-46 156.9 0.0 4.3e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KXX73682.1 - 1.5e-17 63.8 0.1 2.8e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KXX73682.1 - 0.094 12.6 1.9 0.58 10.1 1.3 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PI3_PI4_kinase PF00454.22 KXX73683.1 - 1.4e-31 109.7 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KXX73683.1 - 1.1e-19 69.9 0.0 2.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Cep57_MT_bd PF06657.8 KXX73683.1 - 0.092 12.7 0.1 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Tad PF13400.1 KXX73683.1 - 0.49 10.4 4.2 9.5 6.3 0.4 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like AA_permease_2 PF13520.1 KXX73684.1 - 8.2e-79 265.1 26.3 1e-78 264.8 18.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX73684.1 - 7.9e-13 47.5 19.0 1.2e-12 46.9 13.1 1.3 1 1 0 1 1 1 1 Amino acid permease Cyd_oper_YbgE PF09600.5 KXX73684.1 - 0.0043 17.1 4.8 0.0043 17.1 3.3 2.7 3 0 0 3 3 3 1 Cyd operon protein YbgE (Cyd_oper_YbgE) Lipase_GDSL_2 PF13472.1 KXX73685.1 - 9.3e-17 61.7 0.1 1.1e-16 61.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX73685.1 - 3.6e-13 49.8 0.1 6.1e-13 49.1 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KXX73685.1 - 0.00041 20.1 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FlxA PF14282.1 KXX73686.1 - 1.1 9.2 17.6 1.6 8.7 0.2 4.5 3 1 1 4 4 4 0 FlxA-like protein Filament PF00038.16 KXX73686.1 - 7.7 5.8 47.1 1.1 8.7 9.2 3.2 1 1 2 3 3 3 0 Intermediate filament protein Alpha_kinase PF02816.13 KXX73688.1 - 8.5e-48 162.5 0.0 1.2e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 KXX73688.1 - 9.3e-10 38.8 0.0 2.6e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX73688.1 - 2.5e-05 24.0 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain GAS PF13851.1 KXX73688.1 - 0.7 9.0 10.4 0.25 10.5 0.9 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FAD_binding_4 PF01565.18 KXX73690.1 - 4.4e-31 107.1 0.0 7.4e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KXX73690.1 - 0.014 14.6 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DLH PF01738.13 KXX73691.1 - 4.2e-17 62.1 0.0 2.5e-16 59.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX73691.1 - 1.9e-05 24.4 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX73691.1 - 0.00037 20.4 0.1 0.082 12.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family OPT PF03169.10 KXX73692.1 - 6.4e-179 596.3 53.0 7.3e-179 596.1 36.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 KXX73694.1 - 2.6e-21 76.2 0.0 1.7e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73694.1 - 1.5e-14 54.3 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KXX73694.1 - 7e-07 28.6 0.0 1.2e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KXX73694.1 - 0.00016 21.4 0.0 0.0045 16.6 0.0 2.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KXX73694.1 - 0.005 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX73694.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX73694.1 - 0.019 14.4 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ABC2_membrane PF01061.19 KXX73695.1 - 2.7e-40 137.8 49.4 2.4e-20 72.6 8.4 4.1 4 1 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KXX73695.1 - 1.8e-31 107.8 8.5 1e-29 102.2 0.0 3.9 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.22 KXX73695.1 - 4.2e-09 36.8 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KXX73695.1 - 0.0055 15.9 0.0 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KXX73695.1 - 0.022 14.6 0.0 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 KXX73695.1 - 0.41 9.6 26.6 0.85 8.5 2.4 2.8 2 1 1 3 3 3 0 ABC-2 family transporter protein ABC_tran PF00005.22 KXX73696.1 - 3.9e-06 27.2 0.0 5.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.1 KXX73696.1 - 2.3e-05 24.3 0.1 6.3e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KXX73696.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 KXX73697.1 - 1.2e-14 54.5 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73697.1 - 1.5e-10 41.3 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73697.1 - 2.5e-08 33.8 0.1 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX73697.1 - 0.039 13.3 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX73697.1 - 0.051 13.2 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KXX73697.1 - 0.16 12.3 0.6 0.29 11.5 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SMP PF04927.7 KXX73698.1 - 5.8e-13 48.5 13.1 5.8e-10 38.9 1.8 2.1 1 1 1 2 2 2 2 Seed maturation protein DUF2188 PF09954.4 KXX73698.1 - 1.1 9.1 4.0 0.47 10.4 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) PPR_2 PF13041.1 KXX73699.1 - 8.1e-50 166.5 5.9 5.5e-10 39.0 0.0 13.0 11 4 5 16 16 16 10 PPR repeat family PPR PF01535.15 KXX73699.1 - 8.8e-29 97.4 16.4 5.7e-05 22.8 0.0 14.4 16 0 0 16 16 16 5 PPR repeat PPR_3 PF13812.1 KXX73699.1 - 1e-27 94.0 20.5 2.4e-05 24.2 0.0 15.6 18 0 0 18 18 18 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 KXX73699.1 - 3.8e-22 77.4 0.0 1.3e-08 34.1 0.0 9.5 10 0 0 10 10 10 4 PPR repeat RPM2 PF08579.6 KXX73699.1 - 0.00017 21.7 0.0 0.0025 17.9 0.0 3.0 3 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 KXX73699.1 - 0.054 12.8 0.0 18 4.7 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression ECSIT PF06239.6 KXX73699.1 - 0.054 12.3 0.0 4.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway GHMP_kinases_N PF00288.21 KXX73700.1 - 1.5e-16 60.1 0.6 3e-16 59.2 0.4 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KXX73700.1 - 7.5e-06 26.0 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DDHD PF02862.12 KXX73702.1 - 4.2e-38 131.4 0.0 7e-37 127.4 0.0 2.2 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 KXX73702.1 - 3.5e-05 23.8 0.2 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX73702.1 - 0.00068 19.4 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX73702.1 - 0.0093 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KXX73702.1 - 0.047 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Na_Ca_ex PF01699.19 KXX73703.1 - 1.3e-29 102.6 33.6 3.7e-16 58.9 10.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Nop14 PF04147.7 KXX73703.1 - 0.012 13.5 0.4 0.017 13.0 0.3 1.1 1 0 0 1 1 1 0 Nop14-like family FUSC PF04632.7 KXX73703.1 - 0.025 13.0 1.3 0.049 12.0 0.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family YL1 PF05764.8 KXX73703.1 - 0.04 13.5 1.1 0.057 13.0 0.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 KXX73703.1 - 0.13 10.2 3.0 0.18 9.8 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Toxin-deaminase PF14424.1 KXX73704.1 - 0.062 13.2 0.0 0.071 13.0 0.0 1.3 1 1 0 1 1 1 0 The BURPS668_1122 family of deaminases p450 PF00067.17 KXX73706.1 - 2.6e-65 220.7 0.0 3.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTV_P6 PF06706.6 KXX73706.1 - 0.056 12.9 0.4 0.12 11.8 0.3 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein TauD PF02668.11 KXX73707.1 - 5.7e-41 140.8 0.0 7.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PolyA_pol_arg_C PF12626.2 KXX73707.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus SIR2 PF02146.12 KXX73708.1 - 4.5e-25 88.3 0.7 2.6e-18 66.3 0.0 2.9 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KXX73708.1 - 0.059 13.1 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF1399 PF07173.7 KXX73709.1 - 3.5e-18 66.2 10.5 2.1e-15 57.2 0.3 4.1 3 1 2 5 5 5 2 Protein of unknown function (DUF1399) AbiH PF14253.1 KXX73709.1 - 0.082 12.4 1.1 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4200 PF13863.1 KXX73709.1 - 1.6 8.7 14.2 0.022 14.6 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4066 PF13278.1 KXX73710.1 - 3.4e-27 94.7 0.0 4.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX73710.1 - 1.2e-15 57.2 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family adh_short PF00106.20 KXX73711.1 - 1.5e-21 77.0 4.0 1.8e-21 76.7 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73711.1 - 7.9e-19 68.3 0.0 1.1e-18 67.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73711.1 - 3.7e-06 26.7 1.4 4.7e-06 26.3 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX73711.1 - 0.0012 18.2 0.1 0.0031 16.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX73711.1 - 0.015 15.0 0.5 0.024 14.2 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KXX73711.1 - 0.015 14.1 1.0 0.027 13.3 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.11 KXX73712.1 - 1.3e-39 135.9 51.4 6.8e-39 133.5 17.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73712.1 - 1.5e-16 60.0 0.9 1.5e-16 60.0 0.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Neur_chan_memb PF02932.11 KXX73712.1 - 0.45 10.3 2.8 0.71 9.7 1.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.6 KXX73712.1 - 3.1 7.6 45.6 14 5.4 31.6 2.2 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DIT1_PvcA PF05141.7 KXX73713.1 - 1.2e-94 316.7 0.0 1.5e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MMR_HSR1 PF01926.18 KXX73719.1 - 7.4e-08 32.3 0.0 1.6e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX73719.1 - 1.5e-07 30.7 0.0 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KXX73719.1 - 6.9e-06 25.9 0.8 0.045 13.5 0.2 2.6 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 KXX73719.1 - 1.6e-05 24.1 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KXX73719.1 - 3.5e-05 22.9 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_16 PF13191.1 KXX73719.1 - 0.00015 21.8 0.0 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX73719.1 - 0.00032 20.8 0.0 0.00093 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX73719.1 - 0.00043 21.0 0.8 0.0012 19.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KXX73719.1 - 0.0008 19.7 0.0 0.0033 17.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.8 KXX73719.1 - 0.0011 17.9 0.0 0.0033 16.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SRPRB PF09439.5 KXX73719.1 - 0.0014 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KXX73719.1 - 0.0014 19.1 0.0 0.0035 17.8 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein AAA_29 PF13555.1 KXX73719.1 - 0.0024 17.3 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KXX73719.1 - 0.004 16.2 0.0 0.0084 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KXX73719.1 - 0.0041 16.9 0.6 0.0095 15.8 0.2 2.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KXX73719.1 - 0.0064 16.3 0.2 0.014 15.1 0.1 1.6 2 0 0 2 2 1 1 Domain of unknown function DUF87 T2SE PF00437.15 KXX73719.1 - 0.0084 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 KXX73719.1 - 0.0088 16.3 1.1 0.043 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 KXX73719.1 - 0.009 16.2 0.1 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KXX73719.1 - 0.0094 15.5 0.3 0.23 10.9 0.2 2.2 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KXX73719.1 - 0.0095 16.0 0.5 0.017 15.3 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_10 PF12846.2 KXX73719.1 - 0.0095 15.4 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KXX73719.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_5 PF07728.9 KXX73719.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KXX73719.1 - 0.017 14.1 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SMC_N PF02463.14 KXX73719.1 - 0.034 13.3 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 KXX73719.1 - 0.035 13.7 1.1 0.044 13.4 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 KXX73719.1 - 0.04 12.5 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KXX73719.1 - 0.053 12.9 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 KXX73719.1 - 0.061 12.7 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Ras family IstB_IS21 PF01695.12 KXX73719.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 KXX73719.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX73719.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 KXX73719.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit UPF0079 PF02367.12 KXX73719.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PPV_E1_C PF00519.12 KXX73719.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_PrkA PF08298.6 KXX73719.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Guanylate_kin PF00625.16 KXX73719.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase AIG1 PF04548.11 KXX73720.1 - 8.3e-10 38.1 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 KXX73720.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX73720.1 - 0.0018 18.1 5.7 0.43 10.3 0.0 3.1 2 2 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 KXX73720.1 - 0.013 15.7 1.0 0.046 14.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KXX73720.1 - 0.025 15.3 0.2 0.17 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fe-S_assembly PF04384.8 KXX73720.1 - 0.027 14.8 0.3 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly DUF258 PF03193.11 KXX73720.1 - 0.038 13.1 0.3 0.16 11.1 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KXX73720.1 - 0.039 14.2 0.6 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KXX73720.1 - 0.055 13.7 6.4 0.65 10.2 1.7 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KXX73720.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF87 PF01935.12 KXX73720.1 - 3.2 7.5 7.3 0.6 9.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sec8_exocyst PF04048.9 KXX73723.1 - 8e-50 168.1 0.5 1.6e-49 167.1 0.3 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KXX73723.1 - 2.2e-10 39.9 2.2 4e-10 39.0 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Pkinase PF00069.20 KXX73724.1 - 6e-68 228.8 0.0 8.2e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73724.1 - 2.4e-47 161.2 0.0 3.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX73724.1 - 5.8e-05 22.2 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Chorion_2 PF03964.10 KXX73724.1 - 0.22 12.0 4.8 0.13 12.8 0.9 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF676 PF05057.9 KXX73725.1 - 9.4e-06 25.0 0.0 1.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 KXX73725.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KXX73725.1 - 0.00012 22.0 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX73725.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KXX73725.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KXX73725.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KXX73725.1 - 0.0067 16.0 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KXX73725.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.7 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_9 PF10081.4 KXX73725.1 - 0.017 13.8 0.0 0.044 12.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family DUF2305 PF10230.4 KXX73725.1 - 0.035 13.5 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_8 PF06259.7 KXX73725.1 - 0.043 13.3 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF726 PF05277.7 KXX73725.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) SMI1_KNR4 PF09346.5 KXX73726.1 - 1.6e-36 125.1 0.0 2.4e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Chorion_2 PF03964.10 KXX73726.1 - 0.088 13.3 0.2 0.088 13.3 0.1 3.5 3 1 1 4 4 4 0 Chorion family 2 UPF0220 PF05255.6 KXX73727.1 - 3.1e-53 179.4 2.4 3.4e-53 179.3 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RAI1 PF08652.6 KXX73728.1 - 3.2e-29 100.5 0.0 1.1e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Corona_nucleoca PF00937.13 KXX73728.1 - 0.21 10.5 6.0 0.3 9.9 4.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pap_E4 PF02711.9 KXX73728.1 - 1 10.1 7.9 1.9 9.3 5.4 1.4 1 0 0 1 1 1 0 E4 protein Transglut_core PF01841.14 KXX73729.1 - 6e-12 45.7 0.2 1.4e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KXX73729.1 - 1.8e-08 33.7 0.1 4e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX73729.1 - 2.8e-05 23.3 3.2 3e-05 23.3 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KXX73729.1 - 5.9e-05 22.5 0.2 0.00016 21.1 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain CCDC32 PF14989.1 KXX73729.1 - 0.14 11.9 0.5 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 ABC_tran PF00005.22 KXX73730.1 - 4.6e-15 56.1 0.0 9.8e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX73730.1 - 1e-09 38.8 0.1 0.00041 20.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KXX73730.1 - 0.00013 21.1 0.0 0.27 10.2 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 KXX73730.1 - 0.00021 21.3 0.2 0.00049 20.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KXX73730.1 - 0.00053 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 KXX73730.1 - 0.00057 17.3 0.2 0.00074 17.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.14 KXX73730.1 - 0.0013 17.9 0.0 0.73 9.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KXX73730.1 - 0.0025 17.2 0.4 0.0062 15.9 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KXX73730.1 - 0.0079 16.3 0.1 0.061 13.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KXX73730.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KXX73730.1 - 0.013 16.3 0.6 0.029 15.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KXX73730.1 - 0.014 15.7 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX73730.1 - 0.02 15.0 0.1 0.082 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX73730.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KXX73730.1 - 0.021 14.7 1.0 0.034 14.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KXX73730.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KXX73730.1 - 0.068 13.0 0.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KXX73730.1 - 0.071 13.0 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KXX73730.1 - 0.072 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KXX73730.1 - 0.12 11.8 0.1 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 KXX73730.1 - 0.14 11.3 0.4 0.24 10.6 0.2 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 KXX73730.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 KXX73730.1 - 0.17 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KXX73730.1 - 0.22 10.9 0.3 0.35 10.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Aldedh PF00171.17 KXX73731.1 - 4.2e-133 444.0 0.0 4.8e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX73731.1 - 0.024 13.3 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Ank_4 PF13637.1 KXX73732.1 - 3.6e-51 170.6 14.4 6.4e-10 39.2 0.1 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX73732.1 - 1.8e-46 156.4 2.7 7.9e-18 64.5 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73732.1 - 7.7e-42 139.0 5.1 1.5e-05 24.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KXX73732.1 - 4.5e-35 118.8 9.4 4.8e-10 39.3 0.2 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX73732.1 - 6e-32 106.5 2.4 0.0013 18.7 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat DUF3447 PF11929.3 KXX73732.1 - 0.086 12.6 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) SchA_CurD PF04486.7 KXX73732.1 - 0.098 12.5 0.5 13 5.6 0.0 3.1 1 1 4 5 5 5 0 SchA/CurD like domain Carb_bind PF10645.4 KXX73734.1 - 4.4e-28 96.8 4.3 1.1e-27 95.6 3.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding IGFL PF14653.1 KXX73734.1 - 0.26 11.3 2.3 2.2 8.3 1.5 2.3 1 1 1 2 2 2 0 Insulin growth factor-like family CorA PF01544.13 KXX73737.1 - 3e-27 95.4 4.5 2e-23 82.8 1.7 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Cad PF03596.8 KXX73737.1 - 0.036 13.7 0.5 0.058 13.0 0.3 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter WD40 PF00400.27 KXX73738.1 - 4e-145 467.1 70.8 1.5e-12 46.9 1.5 13.8 13 0 0 13 13 13 13 WD domain, G-beta repeat Nup160 PF11715.3 KXX73738.1 - 1.7e-21 76.0 34.1 0.031 12.4 0.1 12.4 3 3 9 12 12 12 12 Nucleoporin Nup120/160 NACHT PF05729.7 KXX73738.1 - 9.8e-19 67.6 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KXX73738.1 - 1.1e-07 32.0 0.0 8.3e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX73738.1 - 9.6e-07 28.3 0.0 2.7e-05 23.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Cytochrom_D1 PF02239.11 KXX73738.1 - 3.3e-05 22.3 8.2 0.18 10.0 0.3 4.5 3 1 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KXX73738.1 - 3.4e-05 22.7 21.1 0.058 12.1 1.6 6.5 1 1 6 7 7 7 3 Nup133 N terminal like Ank_3 PF13606.1 KXX73738.1 - 0.0015 18.5 0.0 0.15 12.4 0.0 3.8 4 0 0 4 4 3 1 Ankyrin repeat AAA_19 PF13245.1 KXX73738.1 - 0.0019 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Ank_5 PF13857.1 KXX73738.1 - 0.0093 16.1 0.1 0.044 14.0 0.0 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KXX73738.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.1 KXX73738.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_PK PF05891.7 KXX73739.1 - 1.4e-55 187.9 0.1 2e-54 184.1 0.1 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KXX73739.1 - 0.0016 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KXX73739.1 - 0.028 13.5 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 KXX73739.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PGM_PMM_IV PF00408.15 KXX73740.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain SAM_2 PF07647.12 KXX73742.1 - 2.3e-14 52.9 0.1 4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KXX73742.1 - 1.1e-13 50.5 0.0 2.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX73742.1 - 8.9e-12 44.2 0.0 1.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KXX73742.1 - 1.1e-07 31.9 0.0 2.9e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KXX73742.1 - 4.7e-05 23.6 0.1 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 KXX73742.1 - 0.0001 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 KXX73742.1 - 0.046 13.8 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 KXX73742.1 - 0.063 13.3 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Pox_I6 PF04595.8 KXX73742.1 - 0.089 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family Gastrin PF00918.12 KXX73742.1 - 0.12 13.1 1.5 1.2 10.0 0.0 3.1 2 1 0 2 2 2 0 Gastrin/cholecystokinin family DUF952 PF06108.7 KXX73743.1 - 1.5e-22 79.2 0.0 1.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Nucleopor_Nup85 PF07575.8 KXX73744.1 - 9.3e-14 50.5 0.0 6.1e-13 47.8 0.0 2.1 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.9 KXX73744.1 - 0.17 9.9 1.3 0.23 9.5 0.0 1.7 2 0 0 2 2 2 0 Nup93/Nic96 zf-AN1 PF01428.11 KXX73745.1 - 5.6e-11 42.1 8.5 5.6e-11 42.1 5.9 1.6 2 0 0 2 2 2 1 AN1-like Zinc finger ADH_N PF08240.7 KXX73746.1 - 3.2e-28 97.6 1.2 6.7e-28 96.6 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX73746.1 - 4.3e-20 71.5 0.2 8.2e-20 70.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KXX73746.1 - 0.014 14.7 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KXX73746.1 - 0.028 14.2 0.4 0.59 9.9 0.1 2.3 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 KXX73746.1 - 0.029 14.8 0.2 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KXX73746.1 - 0.062 13.3 0.7 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KXX73746.1 - 0.23 10.6 0.1 0.23 10.6 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF676 PF05057.9 KXX73747.1 - 2.5e-51 174.0 0.0 5.9e-51 172.8 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KXX73747.1 - 2.8e-06 27.1 0.0 8.4e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX73747.1 - 1.1e-05 25.4 0.1 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KXX73747.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KXX73747.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2808 PF10989.3 KXX73747.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) HhH-GPD PF00730.20 KXX73748.1 - 2.1e-15 56.9 0.0 3.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KXX73748.1 - 1.6e-07 30.6 0.0 3.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif MDM1 PF15501.1 KXX73748.1 - 0.0091 14.9 6.6 0.013 14.4 4.6 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 Myc_N PF01056.13 KXX73748.1 - 1.8 7.6 9.6 2.8 7.0 6.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TPR_12 PF13424.1 KXX73750.1 - 5.9e-99 324.1 24.9 2.4e-18 65.8 0.0 5.1 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 KXX73750.1 - 1.1e-95 311.2 13.1 1.4e-13 50.2 0.1 8.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73750.1 - 4.8e-21 72.8 14.9 0.0037 16.9 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KXX73750.1 - 9.8e-19 66.7 6.6 1e-05 25.0 0.2 4.8 1 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KXX73750.1 - 1.7e-17 62.2 16.2 0.0039 16.7 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73750.1 - 2.9e-11 42.6 3.0 2.4 8.5 0.0 7.4 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF1925 PF09094.6 KXX73750.1 - 1.8e-10 40.6 4.3 13 5.8 0.0 7.4 7 0 0 7 7 7 0 Domain of unknown function (DUF1925) TPR_2 PF07719.12 KXX73750.1 - 3.1e-10 39.1 17.8 0.19 11.7 0.1 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 KXX73750.1 - 1.7e-09 36.9 0.0 4.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KXX73750.1 - 1.8e-07 31.5 11.0 0.012 16.2 0.0 6.5 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX73750.1 - 3.6e-06 27.1 11.5 1.4 9.7 0.0 8.6 7 2 1 8 8 8 1 Tetratricopeptide repeat Nro1 PF12753.2 KXX73750.1 - 8.5e-06 24.9 0.1 2.2 7.1 0.0 4.9 1 1 4 5 5 5 1 Nuclear pore complex subunit Nro1 TPR_19 PF14559.1 KXX73750.1 - 1.3e-05 25.4 12.7 0.15 12.4 0.0 6.5 2 1 5 7 7 6 2 Tetratricopeptide repeat Lactate_perm PF02652.9 KXX73750.1 - 0.00013 20.6 0.0 21 3.4 0.0 5.0 1 1 5 6 6 6 0 L-lactate permease DUF3856 PF12968.2 KXX73750.1 - 0.00017 21.4 1.0 0.51 10.1 0.1 3.3 1 1 1 3 3 3 3 Domain of Unknown Function (DUF3856) TPR_8 PF13181.1 KXX73750.1 - 0.00023 20.7 11.1 0.89 9.4 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Rab5-bind PF09311.6 KXX73750.1 - 0.00035 20.5 7.7 1 9.1 0.8 5.4 1 1 4 5 5 5 1 Rabaptin-like protein PGAP1 PF07819.8 KXX73750.1 - 0.00054 19.6 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KXX73750.1 - 0.0033 17.1 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX73750.1 - 0.0044 16.9 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX73750.1 - 0.0086 15.3 0.0 0.031 13.5 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) 14-3-3 PF00244.15 KXX73750.1 - 0.057 12.4 0.2 21 4.1 0.0 3.5 1 1 5 6 6 6 0 14-3-3 protein Abhydrolase_8 PF06259.7 KXX73750.1 - 0.2 11.1 0.0 0.46 9.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase TPR_3 PF07720.7 KXX73750.1 - 0.2 11.5 2.5 31 4.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Hemocyanin_N PF03722.9 KXX73750.1 - 0.28 11.3 2.2 49 4.0 0.0 3.5 2 1 3 5 5 5 0 Hemocyanin, all-alpha domain CorA PF01544.13 KXX73750.1 - 3.7 6.4 9.8 20 4.0 0.7 4.2 2 1 3 5 5 5 0 CorA-like Mg2+ transporter protein Pyridoxal_deC PF00282.14 KXX73751.1 - 9e-58 195.4 0.0 1.2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KXX73751.1 - 7.3e-05 21.6 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cwf_Cwc_15 PF04889.7 KXX73752.1 - 3.1 7.4 7.0 5 6.7 4.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CFEM PF05730.6 KXX73753.1 - 0.0075 16.0 2.9 0.0075 16.0 2.0 2.4 2 0 0 2 2 2 1 CFEM domain Peptidase_M24 PF00557.19 KXX73754.1 - 9e-50 169.1 0.2 1.2e-49 168.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KXX73754.1 - 1.1e-35 121.9 0.0 2.2e-35 120.9 0.0 1.5 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain HLH PF00010.21 KXX73755.1 - 3e-16 58.8 0.0 2.4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Herpes_U30 PF04523.8 KXX73755.1 - 0.052 11.0 0.0 0.066 10.6 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 SLX9 PF15341.1 KXX73755.1 - 0.13 12.6 2.1 0.24 11.8 1.5 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 PPE PF00823.14 KXX73755.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 PPE family T5orf172 PF10544.4 KXX73756.1 - 4.8e-16 58.9 1.0 6.4e-16 58.5 0.7 1.2 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KXX73756.1 - 2.3e-11 43.9 0.8 3.4e-11 43.4 0.6 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 ORC6 PF05460.8 KXX73757.1 - 0.0016 17.5 0.5 0.0022 17.1 0.4 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) rve_2 PF13333.1 KXX73757.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain EPL1 PF10513.4 KXX73757.1 - 0.072 13.3 0.5 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like Ank_5 PF13857.1 KXX73758.1 - 5.2e-08 32.8 0.1 1.2e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KXX73758.1 - 0.00013 21.5 0.3 0.00031 20.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KXX73758.1 - 0.00032 20.9 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX73758.1 - 0.00096 19.1 0.0 0.07 13.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KXX73758.1 - 0.0047 17.3 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RNA_pol_3_Rpc31 PF11705.3 KXX73758.1 - 9.3 6.1 11.3 0.65 9.8 0.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 F-box-like PF12937.2 KXX73759.1 - 0.029 14.0 0.0 0.15 11.8 0.0 2.4 2 1 0 2 2 2 0 F-box-like LRR_8 PF13855.1 KXX73759.1 - 0.097 12.4 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat ASCH PF04266.9 KXX73760.1 - 1.5e-12 47.8 0.0 1.9e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 ASCH domain Methyltransf_2 PF00891.13 KXX73761.1 - 8.1e-33 113.6 0.1 3.6e-32 111.4 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase PHO4 PF01384.15 KXX73763.1 - 1.5e-98 329.4 15.5 1.8e-98 329.2 10.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glyco_hydro_16 PF00722.16 KXX73764.1 - 8.2e-11 41.5 0.1 1.3e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.13 KXX73764.1 - 3e-09 36.3 11.1 3e-09 36.3 7.7 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain HET PF06985.6 KXX73767.1 - 1.7e-23 83.2 0.0 3.2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KXX73768.1 - 7e-14 51.3 70.2 5e-12 45.1 43.3 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX73768.1 - 6.4e-08 31.2 27.4 9.8e-08 30.6 19.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CD34_antigen PF06365.7 KXX73768.1 - 0.15 11.6 0.2 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Pyr_redox_2 PF07992.9 KXX73769.1 - 2e-17 63.7 0.0 3.8e-16 59.5 0.0 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX73769.1 - 1.1e-10 41.7 0.3 2.3e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX73769.1 - 0.00011 21.3 0.7 0.059 12.2 0.0 3.7 4 1 0 4 4 4 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KXX73769.1 - 0.00017 20.3 0.1 0.28 9.7 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KXX73769.1 - 0.0013 18.8 0.1 0.012 15.7 0.0 2.4 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX73769.1 - 0.0027 17.5 0.6 12 5.6 0.0 4.1 5 0 0 5 5 5 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX73769.1 - 0.0031 16.4 0.1 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KXX73769.1 - 0.0057 15.5 2.7 3.3 6.5 0.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX73769.1 - 0.025 13.4 0.2 4 6.1 0.0 2.9 3 1 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 KXX73769.1 - 0.026 12.9 0.0 2.2 6.6 0.0 3.2 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.14 KXX73769.1 - 0.073 12.1 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DUF4147 PF13660.1 KXX73769.1 - 0.075 12.1 0.1 1.1 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) NAD_binding_8 PF13450.1 KXX73769.1 - 0.084 12.9 0.0 2.6 8.1 0.0 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CFEM PF05730.6 KXX73770.1 - 1.5e-10 40.7 4.8 2.2e-10 40.1 3.3 1.3 1 0 0 1 1 1 1 CFEM domain UPRTase PF14681.1 KXX73771.1 - 8.1e-35 119.9 0.1 1.4e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KXX73771.1 - 4.4e-08 33.9 0.1 2.4e-07 31.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain HAD PF12710.2 KXX73771.1 - 6.2e-07 29.7 0.1 1.2e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX73771.1 - 1.7e-05 25.3 0.0 5.5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.22 KXX73771.1 - 2.7e-05 23.8 0.2 0.0019 17.9 0.1 2.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_16 PF13191.1 KXX73771.1 - 0.0001 22.3 0.8 0.0003 20.8 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KXX73771.1 - 0.00067 19.9 0.0 0.0024 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KXX73771.1 - 0.0012 17.9 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 KXX73771.1 - 0.0043 17.1 0.1 0.03 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 KXX73771.1 - 0.0052 15.6 0.0 0.015 14.0 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA PF00004.24 KXX73771.1 - 0.019 15.1 0.0 0.17 12.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KXX73771.1 - 0.031 13.9 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 KXX73771.1 - 0.043 13.7 0.3 0.64 9.9 0.2 2.5 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KXX73771.1 - 0.044 12.9 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PRTase_2 PF15609.1 KXX73771.1 - 0.046 13.0 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase AAA_33 PF13671.1 KXX73771.1 - 0.048 13.5 1.7 0.2 11.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 KXX73771.1 - 0.056 12.8 0.3 1.5 8.1 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase Zeta_toxin PF06414.7 KXX73771.1 - 0.064 12.3 0.0 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 KXX73771.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KXX73771.1 - 0.12 12.0 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KXX73771.1 - 0.14 12.3 0.0 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KXX73771.1 - 0.17 10.6 0.0 0.56 9.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain MatE PF01554.13 KXX73772.1 - 2.6e-48 163.6 33.5 8.1e-27 93.8 7.0 2.9 3 1 0 3 3 3 2 MatE HDPD PF02924.9 KXX73772.1 - 0.14 11.9 2.4 0.12 12.1 0.3 1.9 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D YhhN PF07947.9 KXX73773.1 - 4.1e-38 130.6 17.5 6.3e-38 130.0 12.1 1.3 1 0 0 1 1 1 1 YhhN-like protein TMEM219 PF14940.1 KXX73773.1 - 0.012 14.7 0.5 0.018 14.1 0.4 1.3 1 0 0 1 1 1 0 Transmembrane 219 PrgI PF12666.2 KXX73773.1 - 0.46 10.6 7.3 0.072 13.2 1.8 2.2 1 1 1 2 2 2 0 PrgI family protein Neurensin PF14927.1 KXX73773.1 - 1.6 8.1 7.6 8.5 5.7 1.0 3.1 3 1 0 3 3 3 0 Neurensin Acetyltransf_1 PF00583.19 KXX73774.1 - 8.7e-07 28.8 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX73774.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX73774.1 - 0.00086 19.1 0.2 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX73774.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Chitin_bind_3 PF03067.10 KXX73775.1 - 7e-06 26.4 0.3 0.0033 17.7 0.0 2.1 1 1 1 2 2 2 2 Chitin binding domain vATP-synt_E PF01991.13 KXX73777.1 - 1.5e-59 200.5 5.3 1.8e-59 200.3 3.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ENTH PF01417.15 KXX73777.1 - 0.0092 15.8 0.3 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 ENTH domain zf-H2C2_2 PF13465.1 KXX73779.1 - 1.5e-09 37.7 12.2 2.9e-06 27.2 1.3 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KXX73779.1 - 4e-08 33.1 11.5 2.5e-05 24.3 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX73779.1 - 1.1e-05 25.4 7.8 0.00046 20.3 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX73779.1 - 0.0026 17.8 2.8 0.069 13.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KXX73779.1 - 0.0036 17.1 4.7 0.097 12.6 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KXX73779.1 - 0.022 14.9 2.3 0.022 14.9 1.6 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.2 KXX73779.1 - 0.45 10.8 3.9 0.49 10.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SRF-TF PF00319.13 KXX73780.1 - 8.5e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 KXX73780.1 - 0.033 13.4 0.4 0.044 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ctr PF04145.10 KXX73781.1 - 2.3e-29 102.2 0.9 3e-29 101.9 0.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Mg_trans_NIPA PF05653.9 KXX73782.1 - 2.5e-15 56.2 7.1 3.7e-15 55.6 4.9 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KXX73782.1 - 1.9e-05 24.6 16.5 0.00014 21.8 0.2 2.8 3 0 0 3 3 3 2 EamA-like transporter family Tetraspannin PF00335.15 KXX73783.1 - 9.8e-07 28.2 5.9 1.3e-06 27.8 4.1 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2339 PF10101.4 KXX73783.1 - 0.0079 14.5 2.7 0.01 14.1 1.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF805 PF05656.9 KXX73783.1 - 3.2 7.5 7.8 2.2 8.1 3.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF3684 PF12449.3 KXX73784.1 - 0 1410.6 0.0 0 1410.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KXX73784.1 - 2.8e-06 27.0 0.0 5.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.1 KXX73784.1 - 0.0077 16.1 0.1 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 MMtag PF10159.4 KXX73785.1 - 8.4e-31 105.8 1.6 8.4e-31 105.8 1.1 2.2 2 0 0 2 2 2 1 Kinase phosphorylation protein Spt5_N PF11942.3 KXX73785.1 - 4.7 7.8 13.9 6 7.5 4.9 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Hepatitis_core PF00906.15 KXX73785.1 - 9 5.9 11.1 12 5.4 7.7 1.3 1 0 0 1 1 1 0 Hepatitis core antigen adh_short_C2 PF13561.1 KXX73786.1 - 2e-26 93.2 0.7 3.1e-26 92.6 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX73786.1 - 6.1e-26 91.3 2.3 1.5e-25 90.0 1.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX73786.1 - 1.9e-10 40.7 3.4 2.4e-09 37.1 2.3 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX73786.1 - 9.5e-05 22.1 0.1 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KXX73786.1 - 0.0004 19.8 0.3 0.0018 17.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KXX73786.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KXX73786.1 - 0.031 14.0 0.4 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.14 KXX73786.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Metallophos PF00149.23 KXX73787.1 - 1.6e-41 141.9 1.3 2.5e-41 141.3 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2372 PF10178.4 KXX73788.1 - 0.054 13.6 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) TauD PF02668.11 KXX73789.1 - 3.2e-18 66.3 0.0 3.9e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX73789.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 CsiD HA2 PF04408.18 KXX73790.1 - 2.6e-19 69.1 0.0 8e-19 67.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KXX73790.1 - 1.1e-14 54.2 0.0 2.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KXX73790.1 - 1.1e-13 50.8 0.0 4.4e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX73790.1 - 2.7e-08 33.4 0.1 3.8e-07 29.7 0.1 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX73790.1 - 0.00013 22.0 0.1 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KXX73790.1 - 0.0094 15.8 0.0 0.58 9.9 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KXX73790.1 - 0.017 14.3 0.2 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 KXX73790.1 - 0.024 13.5 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KXX73790.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KXX73790.1 - 0.093 13.0 9.1 0.21 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain 2-Hacid_dh_C PF02826.14 KXX73791.1 - 2.2e-49 166.9 0.0 4.1e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX73791.1 - 2.1e-15 56.3 0.0 3.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KXX73791.1 - 0.0011 18.7 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ribosomal_L18e PF00828.14 KXX73792.1 - 1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Med6 PF04934.9 KXX73793.1 - 4.7e-39 133.1 0.0 7.2e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Phosphodiest PF01663.17 KXX73794.1 - 8.8e-15 54.8 0.9 1.6e-14 54.0 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KXX73794.1 - 0.00025 20.5 1.2 0.00043 19.7 0.8 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KXX73794.1 - 0.00049 19.3 0.0 0.00099 18.3 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Meth_synt_2 PF01717.13 KXX73795.1 - 1.6e-139 464.3 0.0 5e-135 449.6 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KXX73795.1 - 4.8e-123 410.3 0.0 4.2e-112 374.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KXX73795.1 - 0.023 13.6 0.0 5.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) EF-hand_4 PF12763.2 KXX73796.1 - 1.5e-26 92.1 0.0 1.3e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KXX73796.1 - 8.8e-05 22.5 0.1 0.15 12.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KXX73796.1 - 0.00019 20.4 0.0 0.32 10.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KXX73796.1 - 0.0003 20.4 0.1 1.3 9.0 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KXX73796.1 - 0.1 12.2 0.1 12 5.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Trp_DMAT PF11991.3 KXX73797.1 - 1.4e-91 307.3 0.0 1.9e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 KXX73799.1 - 1.6e-84 283.7 0.0 3.6e-84 282.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 KXX73799.1 - 2.8e-77 259.5 0.0 2.3e-43 148.1 0.0 2.7 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KXX73799.1 - 3.4e-07 30.4 0.0 8.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX73799.1 - 0.0051 17.7 0.1 0.023 15.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AATase PF07247.7 KXX73799.1 - 1.3 7.4 0.0 4.9 5.5 0.0 1.9 3 0 0 3 3 3 0 Alcohol acetyltransferase IgaA PF07095.6 KXX73800.1 - 0.026 12.2 0.1 0.033 11.9 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF2244 PF10003.4 KXX73800.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Herpes_gE PF02480.11 KXX73800.1 - 0.17 10.1 0.0 0.29 9.3 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E zf-C2H2_4 PF13894.1 KXX73801.1 - 1.3e-05 25.1 13.2 0.17 12.3 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX73801.1 - 0.00015 21.9 12.5 0.1 12.9 2.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type Atg14 PF10186.4 KXX73801.1 - 0.011 14.6 0.7 0.016 14.1 0.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 KXX73801.1 - 0.012 14.9 5.8 0.018 14.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Glyco_hydro_3_C PF01915.17 KXX73801.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Prp19_bind PF06991.6 KXX73801.1 - 0.016 14.4 3.3 0.023 13.9 2.3 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Herpes_BLRF2 PF05812.7 KXX73801.1 - 0.019 14.7 2.1 0.04 13.7 1.4 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TMF_DNA_bd PF12329.3 KXX73801.1 - 0.04 13.7 2.9 0.073 12.8 2.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Parathyroid PF01279.12 KXX73801.1 - 0.074 13.6 1.3 0.17 12.5 0.9 1.5 1 0 0 1 1 1 0 Parathyroid hormone family RNA_pol_Rpb1_1 PF04997.7 KXX73801.1 - 0.075 12.2 0.3 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 BAF1_ABF1 PF04684.8 KXX73801.1 - 0.079 11.8 4.6 0.11 11.3 3.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PALP PF00291.20 KXX73802.1 - 2.4e-33 115.6 0.4 3e-33 115.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KXX73802.1 - 0.038 12.9 0.0 0.067 12.1 0.0 1.4 2 0 0 2 2 2 0 LytB protein Peripla_BP_4 PF13407.1 KXX73802.1 - 0.065 12.5 0.5 11 5.3 0.2 3.0 2 1 0 2 2 2 0 Periplasmic binding protein domain Pkinase PF00069.20 KXX73803.1 - 2e-70 236.9 0.0 5e-70 235.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73803.1 - 6.2e-49 166.3 0.0 1.3e-48 165.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX73803.1 - 0.00074 18.5 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Ric8 PF10165.4 KXX73803.1 - 0.065 12.0 0.2 7.1 5.3 0.1 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Kdo PF06293.9 KXX73803.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MtrA PF04208.9 KXX73803.1 - 0.24 10.8 0.0 0.46 9.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A FPN1 PF06963.7 KXX73804.1 - 0.13 10.6 2.3 0.18 10.1 1.6 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ERG4_ERG24 PF01222.12 KXX73805.1 - 5.2e-134 447.0 18.4 6.3e-134 446.7 12.8 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF218 PF02698.12 KXX73806.1 - 8.2e-08 31.8 0.0 2.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 DUF218 domain Mur_ligase_M PF08245.7 KXX73807.1 - 5.5e-06 26.5 0.1 1.1e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KXX73807.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Arginase PF00491.16 KXX73808.1 - 0.14 11.4 0.2 0.34 10.1 0.2 1.7 1 1 0 1 1 1 0 Arginase family Abhydrolase_5 PF12695.2 KXX73809.1 - 2e-05 24.3 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KXX73809.1 - 0.023 13.9 0.0 0.068 12.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family LysM PF01476.15 KXX73811.1 - 1.4e-27 95.3 0.4 6.9e-05 22.6 0.0 6.4 6 0 0 6 6 6 6 LysM domain Astacin PF01400.19 KXX73812.1 - 0.001 18.4 1.5 0.046 13.1 0.4 3.3 4 0 0 4 4 4 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KXX73812.1 - 0.0058 16.3 0.1 0.041 13.6 0.2 2.2 2 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.1 KXX73812.1 - 0.014 14.9 0.1 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX73812.1 - 0.028 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX73812.1 - 0.084 12.9 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KXX73812.1 - 0.13 11.1 0.2 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase M66 DUF3433 PF11915.3 KXX73814.1 - 1e-10 41.5 11.8 2e-06 27.8 1.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Chlorosome_CsmC PF11098.3 KXX73814.1 - 0.009 15.7 0.1 0.023 14.3 0.1 1.7 1 0 0 1 1 1 1 Chlorosome envelope protein C Glyco_hydro_18 PF00704.23 KXX73815.1 - 2e-73 247.7 0.0 2.9e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KXX73815.1 - 6.8e-08 32.3 8.7 6.8e-08 32.3 6.0 2.6 2 0 0 2 2 2 1 Chitin recognition protein Lipase_GDSL_2 PF13472.1 KXX73816.1 - 4.9e-12 46.3 0.0 1.7e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX73816.1 - 8.3e-06 25.7 0.8 4.7e-05 23.3 0.5 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ADH_zinc_N PF00107.21 KXX73817.1 - 6.1e-10 38.7 0.4 9.9e-10 38.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX73817.1 - 1.9e-08 33.9 0.0 5.5e-08 32.5 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.13 KXX73818.1 - 2.6e-13 49.4 0.1 3.9e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73818.1 - 3.4e-09 36.4 7.4 3.4e-09 36.4 5.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KXX73818.1 - 0.11 12.2 0.1 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MFS_1 PF07690.11 KXX73819.1 - 0.00062 18.5 35.0 0.0018 17.0 21.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KXX73820.1 - 3.9e-19 68.5 14.3 6.3e-14 51.4 3.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73820.1 - 5.2e-06 25.2 2.9 6.5e-06 24.9 1.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KXX73820.1 - 0.02 13.0 4.9 0.027 12.6 3.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector FAD_binding_3 PF01494.14 KXX73821.1 - 1.4e-13 50.6 0.4 2e-05 23.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KXX73821.1 - 0.021 14.8 0.3 0.082 12.9 0.1 2.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4524 PF15025.1 KXX73821.1 - 0.22 10.9 0.6 0.92 8.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) Methyltransf_2 PF00891.13 KXX73822.1 - 2.9e-12 46.3 0.0 3.7e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HET PF06985.6 KXX73823.1 - 1.6e-11 44.5 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KXX73824.1 - 9.7e-76 255.1 0.0 1.2e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KXX73825.1 - 1e-16 60.9 8.2 1.7e-11 43.8 1.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX73825.1 - 6.7e-08 31.8 4.7 3.2e-06 26.2 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX73825.1 - 8.8e-07 28.1 0.0 1.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KXX73825.1 - 1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX73825.1 - 0.00034 20.7 0.1 0.00097 19.2 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX73825.1 - 0.00051 19.9 1.1 0.00095 19.1 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX73825.1 - 0.0013 17.6 0.2 0.0025 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KXX73825.1 - 0.0017 17.5 0.1 0.0032 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KXX73825.1 - 0.0019 16.8 3.5 0.062 11.9 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 KXX73825.1 - 0.0021 18.4 1.2 0.0083 16.5 0.7 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX73825.1 - 0.0051 16.8 5.3 0.011 15.7 0.7 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KXX73825.1 - 0.036 12.9 0.3 0.051 12.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 KXX73825.1 - 0.066 12.2 0.3 5.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KXX73825.1 - 0.086 11.3 0.3 0.14 10.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N PF00107.21 KXX73826.1 - 2.9e-11 43.0 0.1 1.3e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX73826.1 - 3.4e-08 33.2 0.1 8.8e-07 28.6 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.18 KXX73827.1 - 5.8e-19 67.9 0.4 1.5e-11 43.9 0.0 2.4 1 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 KXX73827.1 - 8.2e-09 35.2 0.0 2.7e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like BTB PF00651.26 KXX73828.1 - 0.051 13.5 0.1 3.4 7.6 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain SRP19 PF01922.12 KXX73829.1 - 8.7e-29 99.9 0.0 1.5e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein OMPdecase PF00215.19 KXX73830.1 - 8.9e-96 319.6 0.1 1.3e-95 319.0 0.1 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Dak2 PF02734.12 KXX73830.1 - 0.061 12.9 3.9 0.11 12.1 2.7 1.5 1 0 0 1 1 1 0 DAK2 domain CDP-OH_P_transf PF01066.16 KXX73831.1 - 7.9e-18 64.6 3.7 7.9e-18 64.6 2.6 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cyt-b5 PF00173.23 KXX73832.1 - 2.7e-20 71.9 0.1 1.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KXX73832.1 - 1.4e-07 31.9 22.6 2e-07 31.3 14.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_1 PF00076.17 KXX73833.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KXX73833.1 - 1.6 7.1 20.2 1.9 6.8 14.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PP2C PF00481.16 KXX73834.1 - 1e-35 123.3 0.0 3e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KXX73834.1 - 0.00083 18.8 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KXX73834.1 - 0.022 14.4 0.1 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Het-C PF07217.6 KXX73835.1 - 2.5e-292 970.5 0.0 2.9e-292 970.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Dynactin PF12455.3 KXX73836.1 - 4.2e-95 317.7 7.0 4.2e-95 317.7 4.8 3.1 3 2 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KXX73836.1 - 9.3e-24 82.9 0.6 1.7e-23 82.0 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 KXX73836.1 - 3.7 6.6 25.2 0.19 10.8 1.3 4.6 2 1 2 5 5 5 0 Reovirus sigma C capsid protein Fungal_trans PF04082.13 KXX73837.1 - 8.5e-11 41.2 3.1 3.1e-09 36.0 0.0 3.7 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73837.1 - 5.9e-07 29.2 11.5 1e-06 28.5 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX73838.1 - 1e-24 86.8 0.0 8.4e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73838.1 - 7e-09 35.4 7.4 1.4e-08 34.5 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX73839.1 - 2.1e-51 174.7 0.0 3.1e-25 88.6 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73839.1 - 0.00021 21.1 7.2 0.00042 20.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 KXX73839.1 - 3.6 7.3 55.5 0.45 10.2 33.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein EphA2_TM PF14575.1 KXX73840.1 - 0.047 14.0 0.5 0.1 12.9 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KXX73840.1 - 0.15 11.6 0.3 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain IncA PF04156.9 KXX73840.1 - 0.26 10.8 0.4 0.41 10.2 0.3 1.2 1 0 0 1 1 1 0 IncA protein HAMP PF00672.20 KXX73840.1 - 0.27 11.4 1.2 0.59 10.3 0.9 1.5 1 0 0 1 1 1 0 HAMP domain TMEM154 PF15102.1 KXX73840.1 - 0.45 10.2 3.4 1.1 8.9 2.4 1.6 1 1 0 1 1 1 0 TMEM154 protein family FAD_binding_3 PF01494.14 KXX73842.1 - 1.3e-72 244.8 0.0 1.7e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KXX73842.1 - 3e-43 147.3 0.0 5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KXX73842.1 - 0.00027 21.2 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX73842.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX73842.1 - 0.0071 15.3 0.0 0.026 13.4 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX73842.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 KXX73842.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Thi4 PF01946.12 KXX73842.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KXX73842.1 - 0.045 12.2 0.0 0.079 11.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KXX73842.1 - 0.056 12.3 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KXX73842.1 - 0.084 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KXX73842.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family GDI PF00996.13 KXX73842.1 - 0.21 9.8 0.0 0.33 9.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Fasciclin PF02469.17 KXX73844.1 - 6e-15 55.3 0.0 7.4e-13 48.6 0.0 2.7 3 0 0 3 3 3 2 Fasciclin domain SnoaL_4 PF13577.1 KXX73845.1 - 2.6e-47 159.8 4.0 4.2e-18 65.4 0.1 3.5 3 0 0 3 3 3 3 SnoaL-like domain SnoaL_3 PF13474.1 KXX73845.1 - 0.0032 17.5 1.2 0.23 11.4 0.0 3.5 3 1 0 3 3 3 1 SnoaL-like domain DUF221 PF02714.10 KXX73846.1 - 1e-103 346.6 11.1 2.4e-103 345.4 7.7 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KXX73846.1 - 5.8e-42 142.9 0.6 5.8e-42 142.9 0.4 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KXX73846.1 - 2.7e-27 94.4 1.8 1e-26 92.6 0.1 2.4 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 KXX73846.1 - 9.4e-10 38.8 0.0 2.5e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KXX73846.1 - 0.0037 17.2 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1180 PF06679.7 KXX73846.1 - 0.0087 15.9 0.3 6.8 6.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) RRM_1 PF00076.17 KXX73846.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX73846.1 - 0.13 12.0 0.0 0.53 10.1 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3040 PF11239.3 KXX73847.1 - 0.73 9.9 3.1 8.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Herpes_gE PF02480.11 KXX73850.1 - 0.0033 15.7 0.3 0.0047 15.2 0.0 1.4 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KXX73850.1 - 0.024 13.4 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM240 PF15207.1 KXX73850.1 - 0.051 13.1 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 TMEM240 family Protocadherin PF08374.6 KXX73850.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Herpes_UL37_2 PF07413.6 KXX73850.1 - 0.21 10.3 1.1 0.29 9.9 0.7 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 MFS_1 PF07690.11 KXX73851.1 - 2.1e-45 154.9 33.7 2.3e-43 148.2 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX73851.1 - 2.5e-10 39.3 23.6 4.1e-10 38.6 3.1 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 KXX73851.1 - 0.063 11.3 5.7 0.12 10.3 0.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RRP7 PF12923.2 KXX73852.1 - 2e-35 121.6 7.9 2e-35 121.6 5.5 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) ADIP PF11559.3 KXX73853.1 - 1.1e-41 142.2 7.8 1.1e-41 142.2 5.4 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 KXX73853.1 - 0.016 14.8 8.8 0.032 13.8 4.9 2.0 2 0 0 2 2 2 0 IncA protein DivIVA PF05103.8 KXX73853.1 - 0.38 10.7 10.9 12 5.9 5.9 3.0 2 0 0 2 2 2 0 DivIVA protein NmrA PF05368.8 KXX73854.1 - 4.4e-11 42.4 0.0 1.9e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX73854.1 - 1.3e-08 35.1 0.0 3.2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX73854.1 - 6.9e-05 21.9 0.0 9.5e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KXX73854.1 - 0.0027 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KXX73854.1 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain CsbD PF05532.7 KXX73855.1 - 4.9e-20 70.9 19.3 8.6e-12 44.5 1.1 3.1 2 1 1 3 3 3 3 CsbD-like F-box PF00646.28 KXX73856.1 - 0.0025 17.4 0.5 0.0052 16.4 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX73856.1 - 0.7 9.6 3.1 0.57 9.9 0.3 2.2 2 0 0 2 2 2 0 F-box-like MOSC PF03473.12 KXX73857.1 - 4.5e-17 61.7 0.0 9.8e-17 60.6 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 KXX73857.1 - 5.5e-10 38.8 0.7 1.2e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 KXX73857.1 - 9.2e-05 22.9 0.1 0.00049 20.6 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.4 KXX73857.1 - 0.18 11.3 2.2 0.4 10.2 1.5 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Aminotran_5 PF00266.14 KXX73858.1 - 2.6e-97 325.9 0.0 3.1e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KXX73858.1 - 3.8e-08 32.8 0.0 5.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KXX73858.1 - 7.7e-06 25.1 0.0 2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KXX73858.1 - 0.0018 16.8 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KXX73858.1 - 0.063 11.5 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.13 KXX73859.1 - 1.1e-65 221.4 9.8 1.3e-65 221.1 6.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KXX73859.1 - 6.5e-15 54.2 0.0 1.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX73859.1 - 1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX73859.1 - 8.1e-10 38.0 0.3 3.6e-09 35.9 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain APG6 PF04111.7 KXX73859.1 - 0.8 8.6 10.2 1.9 7.4 4.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 KXX73859.1 - 6.3 5.7 8.0 0.48 9.4 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Amidase PF01425.16 KXX73860.1 - 7.4e-33 114.0 0.9 1e-31 110.2 0.4 2.1 2 0 0 2 2 2 2 Amidase C1_1 PF00130.17 KXX73861.1 - 0.0051 16.5 0.8 0.0089 15.7 0.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.7 KXX73861.1 - 0.16 11.3 1.2 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF1168 PF06658.7 KXX73862.1 - 1.2e-40 138.3 13.8 1.6e-40 137.9 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNA_polI_A34 PF08208.6 KXX73862.1 - 0.012 15.2 11.1 0.015 15.0 7.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 eIF-3_zeta PF05091.7 KXX73862.1 - 0.033 12.8 2.4 0.035 12.7 1.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GP40 PF11025.3 KXX73862.1 - 0.18 11.3 0.7 0.29 10.6 0.5 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium U79_P34 PF03064.11 KXX73862.1 - 0.27 10.7 13.3 0.44 10.0 9.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 KXX73862.1 - 0.29 10.9 3.6 0.36 10.6 2.5 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 KXX73862.1 - 0.7 8.0 5.5 0.76 7.9 3.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 KXX73862.1 - 0.86 8.3 8.1 1.2 7.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4603 PF15376.1 KXX73862.1 - 2.4 5.2 7.3 2.7 5.0 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) HSP90 PF00183.13 KXX73862.1 - 2.6 6.3 10.5 3.1 6.0 7.3 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF2722 PF10846.3 KXX73862.1 - 2.6 6.9 12.9 0.3 10.0 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RNase_H2-Ydr279 PF09468.5 KXX73862.1 - 2.7 7.0 8.1 3.5 6.7 5.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 KXX73862.1 - 3.8 7.1 15.0 5.7 6.5 10.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 YqfQ PF14181.1 KXX73862.1 - 4.9 7.1 8.2 8.5 6.3 5.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein Herpes_DNAp_acc PF04929.7 KXX73862.1 - 4.9 6.0 6.6 5.6 5.8 4.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DNA_pol3_a_NII PF11490.3 KXX73862.1 - 6.9 6.3 11.4 10 5.7 7.9 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Peptidase_S49_N PF08496.5 KXX73862.1 - 9.9 5.9 6.6 14 5.4 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal 3Beta_HSD PF01073.14 KXX73863.1 - 9.5e-27 93.4 0.0 6.2e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX73863.1 - 3.8e-14 52.7 0.0 7.7e-14 51.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX73863.1 - 8.2e-09 34.7 0.0 5.1e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KXX73863.1 - 1.7e-07 31.4 0.0 1.8e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX73863.1 - 3e-05 23.9 0.9 7.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KXX73863.1 - 8e-05 21.6 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KXX73863.1 - 0.0022 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 KR domain His_Phos_1 PF00300.17 KXX73864.1 - 1.1e-31 110.0 0.0 2.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KXX73864.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SKG6 PF08693.5 KXX73865.1 - 2.5e-09 36.3 3.4 4.8e-09 35.3 2.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KXX73865.1 - 0.00078 19.1 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 KXX73865.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CcmD PF04995.9 KXX73865.1 - 0.049 13.3 0.8 0.088 12.5 0.5 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1469 PF07332.6 KXX73865.1 - 0.081 12.6 0.0 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) EphA2_TM PF14575.1 KXX73865.1 - 0.084 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KXX73865.1 - 0.087 11.0 0.0 0.087 11.0 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3301 PF11743.3 KXX73865.1 - 0.18 11.3 0.2 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) DUF4366 PF14283.1 KXX73865.1 - 0.29 10.5 0.6 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HECT PF00632.20 KXX73866.1 - 6.5e-53 179.9 0.0 6.7e-35 120.7 0.0 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Cpn60_TCP1 PF00118.19 KXX73867.1 - 3e-163 543.9 0.2 3.4e-163 543.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NAD_binding_10 PF13460.1 KXX73869.1 - 5.9e-11 42.7 0.0 9.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX73869.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family C2 PF00168.25 KXX73870.1 - 8.9e-15 54.3 0.0 9.9e-13 47.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 KXX73870.1 - 0.00023 21.2 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Glycos_transf_N PF04413.11 KXX73870.1 - 0.0093 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) NHL PF01436.16 KXX73871.1 - 4.8e-06 26.2 0.0 0.2 11.7 0.0 4.2 3 1 1 4 4 4 2 NHL repeat SBBP PF06739.6 KXX73871.1 - 7.7e-05 22.3 0.2 0.39 10.5 0.0 3.3 3 0 0 3 3 3 2 Beta-propeller repeat GSDH PF07995.6 KXX73871.1 - 0.00015 20.9 2.7 0.008 15.2 0.8 3.1 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KXX73871.1 - 0.00017 21.0 0.0 0.11 11.8 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KXX73871.1 - 0.014 14.4 0.2 2.2 7.3 0.1 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller RCC1_2 PF13540.1 KXX73871.1 - 0.11 12.1 2.4 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KXX73873.1 - 3.4e-13 48.9 3.8 0.0016 18.2 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat FAD_binding_3 PF01494.14 KXX73874.1 - 2e-15 56.7 0.2 4.9e-14 52.1 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX73874.1 - 0.046 13.7 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 KXX73875.1 - 5.5e-28 97.6 0.0 3e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 KXX73876.1 - 4.2e-40 134.2 12.2 7.1e-13 47.8 0.3 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 KXX73876.1 - 1.7e-09 37.5 0.1 9.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Nup160 PF11715.3 KXX73876.1 - 5e-07 28.2 4.2 0.031 12.4 0.3 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_16 PF13191.1 KXX73876.1 - 3.7e-06 27.0 0.2 1.4e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KXX73876.1 - 0.0031 16.4 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Nbas_N PF15492.1 KXX73876.1 - 0.01 14.9 6.0 3.8 6.5 0.1 3.6 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal AAA PF00004.24 KXX73876.1 - 0.012 15.8 0.1 0.042 14.0 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KXX73876.1 - 0.032 13.9 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KXX73876.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.12 KXX73876.1 - 0.11 11.8 0.1 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.1 KXX73876.1 - 0.29 11.4 1.2 1.4 9.2 0.1 2.7 3 1 0 3 3 3 0 AAA domain DUF1045 PF06299.7 KXX73877.1 - 0.028 14.0 0.5 0.051 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) OTU PF02338.14 KXX73878.1 - 4.1e-15 56.4 0.2 6e-14 52.6 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KXX73878.1 - 4.6e-05 22.8 0.0 0.021 14.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain adh_short PF00106.20 KXX73879.1 - 2.5e-25 89.3 0.4 3.5e-25 88.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73879.1 - 1.7e-21 77.1 0.0 2.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73879.1 - 5.5e-10 39.2 0.0 8.8e-10 38.5 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_11 PF14833.1 KXX73880.1 - 0.087 12.8 0.2 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CAP_N PF01213.14 KXX73880.1 - 0.23 10.6 2.4 0.24 10.6 1.7 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GST_C_3 PF14497.1 KXX73881.1 - 0.00021 21.7 0.1 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 KXX73881.1 - 0.00066 19.9 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 KXX73881.1 - 0.0082 16.0 0.5 0.023 14.5 0.2 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Mcp5_PH PF12814.2 KXX73882.1 - 3.1e-47 159.5 0.0 6.8e-47 158.4 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology YkyA PF10368.4 KXX73882.1 - 0.073 12.4 6.9 0.13 11.6 4.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein GAS PF13851.1 KXX73882.1 - 0.079 12.1 12.3 0.13 11.4 8.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KXX73882.1 - 0.43 10.3 20.4 0.063 13.0 7.3 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bunya_RdRp PF04196.7 KXX73882.1 - 0.55 8.1 0.0 0.97 7.3 0.0 1.3 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase CENP-F_leu_zip PF10473.4 KXX73882.1 - 0.56 10.0 17.4 1.1 9.1 12.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KXX73882.1 - 0.72 9.3 4.3 2.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.15 KXX73882.1 - 3.6 7.3 12.1 25 4.7 1.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 KXX73882.1 - 4.1 7.4 7.8 2.4 8.2 3.3 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAD_2 PF13419.1 KXX73883.1 - 6.6e-27 94.8 0.2 2.4e-26 93.0 0.1 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX73883.1 - 2.8e-09 37.6 0.0 6.2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX73883.1 - 4e-07 29.6 0.1 8.1e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Voltage_CLC PF00654.15 KXX73884.1 - 2.1e-93 313.1 19.6 2.1e-93 313.1 13.6 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 KXX73884.1 - 0.014 15.3 3.4 0.014 15.3 2.4 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Paf1 PF03985.8 KXX73885.1 - 6.4e-57 193.2 2.5 1.2e-56 192.2 1.8 1.4 1 1 0 1 1 1 1 Paf1 Cylicin_N PF15241.1 KXX73885.1 - 0.036 13.9 0.2 0.083 12.7 0.2 1.6 1 0 0 1 1 1 0 Cylicin N-terminus BTV_NS2 PF04514.7 KXX73885.1 - 7.8 5.2 8.5 12 4.6 5.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ribosomal_L7Ae PF01248.21 KXX73886.1 - 1.5e-28 98.1 0.7 1.9e-28 97.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KXX73886.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase PF00639.16 KXX73887.1 - 1.6e-18 67.1 0.1 3.1e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KXX73887.1 - 2.4e-18 66.4 0.6 3.8e-18 65.8 0.4 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KXX73887.1 - 3.8e-06 27.5 0.1 5.6e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Glyco_transf_90 PF05686.7 KXX73888.1 - 0.097 11.3 7.7 1.4 7.5 2.8 2.9 2 1 0 2 2 2 0 Glycosyl transferase family 90 Ribosomal_S8 PF00410.14 KXX73889.1 - 8.3e-26 90.3 0.1 1.1e-25 89.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TCTP PF00838.12 KXX73891.1 - 1.2e-59 201.0 1.9 1.3e-59 200.8 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 KXX73891.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family DUF357 PF04010.8 KXX73891.1 - 0.16 11.6 1.7 0.35 10.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) RRF PF01765.14 KXX73891.1 - 0.29 10.5 1.6 0.98 8.8 0.5 1.9 2 0 0 2 2 2 0 Ribosome recycling factor Neurochondrin PF05536.6 KXX73892.1 - 5.1e-110 368.3 0.0 9.6e-110 367.4 0.0 1.4 1 1 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 KXX73892.1 - 0.11 12.1 3.1 0.23 11.1 1.0 2.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Voltage_CLC PF00654.15 KXX73893.1 - 1.8e-92 310.1 27.2 1.8e-92 310.1 18.9 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel NRDE-2 PF08424.5 KXX73894.1 - 2.4e-81 273.1 0.0 7.1e-80 268.2 0.0 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KXX73894.1 - 7e-05 23.1 8.9 0.7 10.6 0.3 6.8 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73894.1 - 0.06 13.5 0.9 25 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3439 PF11921.3 KXX73895.1 - 3.8 7.2 11.1 0.23 11.2 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Glyco_hydro_16 PF00722.16 KXX73896.1 - 4.2e-11 42.4 3.0 6.4e-11 41.8 2.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ketoacyl-synt PF00109.21 KXX73897.1 - 1.6e-58 198.2 8.4 4.8e-57 193.3 1.3 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX73897.1 - 3.8e-35 120.3 2.0 1.8e-34 118.1 1.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KXX73897.1 - 8.6e-06 24.9 0.1 9.1e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX73897.1 - 0.0011 18.3 4.1 0.0085 15.5 0.2 3.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain OPT PF03169.10 KXX73898.1 - 1.2e-189 631.7 44.7 1.4e-189 631.5 31.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dioxygenase_C PF00775.16 KXX73899.1 - 1e-51 174.8 0.0 1.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KXX73899.1 - 3.3e-12 46.2 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KXX73899.1 - 1.3e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 KXX73900.1 - 2.8e-26 91.9 0.0 5e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX73900.1 - 8.8e-06 25.5 16.3 1.6e-05 24.6 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Biotin_lipoyl PF00364.17 KXX73902.1 - 6.8e-21 73.6 0.6 1.3e-20 72.7 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KXX73902.1 - 2.2e-08 33.5 0.0 8.3e-08 31.7 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KXX73902.1 - 7.9e-05 22.2 1.7 0.00073 19.1 0.0 3.0 3 1 1 4 4 4 1 Biotin-lipoyl like HlyD_2 PF12700.2 KXX73902.1 - 0.0052 15.9 0.3 0.15 11.1 0.2 2.1 1 1 0 1 1 1 1 HlyD family secretion protein HlyD_3 PF13437.1 KXX73902.1 - 0.0091 16.3 0.2 1.8 8.9 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein QRPTase_N PF02749.11 KXX73902.1 - 0.066 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.12 KXX73903.1 - 2.6e-24 85.5 0.6 9.2e-23 80.4 0.1 2.4 2 0 0 2 2 2 2 CoA-transferase family III Pkinase PF00069.20 KXX73904.1 - 1.5e-75 253.7 0.0 1.8e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73904.1 - 1.3e-37 129.3 0.0 1.8e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX73904.1 - 0.0082 15.1 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX73904.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SCA7 PF08313.7 KXX73905.1 - 1.2e-34 117.7 0.4 4.1e-34 116.0 0.3 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain PSD1 PF07587.6 KXX73905.1 - 0.018 14.4 0.2 0.018 14.4 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Omega-toxin PF06357.6 KXX73905.1 - 0.11 12.1 0.2 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Omega-atracotoxin DUF3128 PF11326.3 KXX73905.1 - 0.54 10.4 3.5 1.6 8.8 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Acyltransferase PF01553.16 KXX73906.1 - 4.6e-14 51.9 0.0 7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PH_9 PF15410.1 KXX73907.1 - 1.3e-09 38.1 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain YonK PF09642.5 KXX73907.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 YonK protein NTF2 PF02136.15 KXX73908.1 - 2.7e-24 85.7 0.2 4.5e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KXX73908.1 - 1.7e-08 33.9 0.1 3.1e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX73908.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX73908.1 - 8.4e-05 22.3 0.1 0.00029 20.6 0.0 2.0 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 KXX73908.1 - 0.00065 19.4 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KXX73908.1 - 3.8 5.6 30.8 4.7 5.3 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nnf1 PF03980.9 KXX73909.1 - 8.1e-23 80.4 3.3 8.1e-23 80.4 2.3 1.5 2 0 0 2 2 2 1 Nnf1 TPR_MLP1_2 PF07926.7 KXX73909.1 - 0.0021 17.8 0.8 0.0021 17.8 0.6 1.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein YqjK PF13997.1 KXX73909.1 - 0.0034 17.5 0.7 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 YqjK-like protein Cortex-I_coil PF09304.5 KXX73909.1 - 0.02 14.9 1.8 0.02 14.9 1.3 1.9 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF3584 PF12128.3 KXX73909.1 - 0.034 11.4 1.8 0.036 11.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF641 PF04859.7 KXX73909.1 - 0.089 12.5 3.8 0.73 9.5 2.1 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMCO5 PF14992.1 KXX73909.1 - 0.11 11.6 0.6 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 TMCO5 family CASP_C PF08172.7 KXX73909.1 - 0.14 11.1 4.0 0.033 13.2 0.8 1.3 2 0 0 2 2 2 0 CASP C terminal COMP PF11598.3 KXX73909.1 - 0.2 11.7 3.6 0.37 10.9 1.1 2.4 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Dzip-like_N PF13815.1 KXX73909.1 - 0.38 10.5 3.4 0.82 9.4 1.8 2.0 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Enkurin PF13864.1 KXX73909.1 - 0.43 10.8 3.9 0.18 12.0 1.1 1.6 2 1 0 2 2 2 0 Calmodulin-binding IncA PF04156.9 KXX73909.1 - 0.71 9.4 4.2 0.51 9.9 1.7 1.6 1 1 1 2 2 2 0 IncA protein FliT PF05400.8 KXX73909.1 - 2 8.8 9.7 0.63 10.4 2.0 2.5 3 0 0 3 3 3 0 Flagellar protein FliT GrpE PF01025.14 KXX73909.1 - 2 7.9 5.1 0.9 9.0 1.3 2.0 1 1 0 2 2 2 0 GrpE DivIC PF04977.10 KXX73909.1 - 2.2 7.8 7.7 0.12 11.8 0.6 2.2 3 0 0 3 3 3 0 Septum formation initiator DUF4140 PF13600.1 KXX73909.1 - 3.2 8.2 8.5 0.28 11.6 0.9 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 KXX73909.1 - 4 7.6 10.8 0.6 10.2 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Halo_GVPC PF05465.8 KXX73909.1 - 4.6 7.2 5.4 1.7 8.6 0.3 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat TMF_TATA_bd PF12325.3 KXX73909.1 - 6.5 6.5 9.2 2.7 7.7 2.9 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-C3HC4_2 PF13923.1 KXX73910.1 - 1.8e-08 34.2 20.5 6.7e-06 26.0 5.1 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX73910.1 - 1.4e-06 27.9 14.7 1.4e-06 27.9 4.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KXX73910.1 - 2e-06 27.3 17.0 9.7e-06 25.1 5.9 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KXX73910.1 - 1.5e-05 24.3 8.7 1.5e-05 24.3 6.1 3.0 1 1 3 4 4 4 2 Rtf2 RING-finger zf-RING_2 PF13639.1 KXX73910.1 - 2e-05 24.2 16.1 4.5e-05 23.1 3.9 2.9 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.1 KXX73910.1 - 6.2e-05 22.6 4.7 6.2e-05 22.6 3.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 KXX73910.1 - 7.2e-05 22.1 2.1 0.041 13.3 0.0 2.9 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4 PF00097.20 KXX73910.1 - 0.0003 20.3 20.4 0.001 18.7 4.9 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX73910.1 - 0.0038 17.0 7.1 0.0038 17.0 4.9 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 KXX73910.1 - 0.0062 16.4 15.0 0.011 15.6 5.7 2.9 2 1 1 3 3 3 2 FYVE zinc finger DZR PF12773.2 KXX73910.1 - 7.2 6.5 18.3 24 4.8 7.4 3.6 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 KXX73910.1 - 7.4 6.4 16.8 10 5.9 5.0 3.2 3 1 0 3 3 2 0 zinc-ribbons Prok-RING_4 PF14447.1 KXX73910.1 - 9 5.9 11.9 0.3 10.6 0.6 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Peptidase_M28 PF04389.12 KXX73912.1 - 9e-41 139.5 0.0 1.1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Zn_clus PF00172.13 KXX73913.1 - 2.8e-08 33.5 8.9 5.4e-08 32.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX73913.1 - 1.3e-05 24.0 0.1 6.5e-05 21.7 0.1 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Na_sulph_symp PF00939.14 KXX73913.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region Mito_carr PF00153.22 KXX73914.1 - 1.5e-43 146.4 0.3 3e-14 52.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 KXX73914.1 - 0.06 13.7 1.5 0.19 12.1 0.1 2.4 3 0 0 3 3 3 0 YtxH-like protein PGG PF13962.1 KXX73915.1 - 5.2 6.7 10.4 14 5.3 7.2 1.7 1 1 0 1 1 1 0 Domain of unknown function Amidoligase_2 PF12224.3 KXX73916.1 - 4.8e-18 65.6 0.0 7.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Dynamin_N PF00350.18 KXX73917.1 - 8.3e-29 100.5 0.0 1.5e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX73917.1 - 9.7e-14 50.8 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KXX73917.1 - 0.00038 20.4 0.0 0.0029 17.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Phage_tail_X PF05489.7 KXX73917.1 - 0.0045 16.4 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 Phage Tail Protein X FeoB_N PF02421.13 KXX73917.1 - 0.022 14.0 0.0 0.88 8.8 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B GED PF02212.13 KXX73917.1 - 0.025 14.4 0.7 0.089 12.6 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain B56 PF01603.15 KXX73917.1 - 0.031 12.8 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) FtsK_SpoIIIE PF01580.13 KXX73917.1 - 0.058 12.8 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 KXX73917.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Ceramidase PF05875.7 KXX73918.1 - 0.064 12.3 0.2 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Ceramidase Ribonuc_L-PSP PF01042.16 KXX73919.1 - 2.7e-10 40.0 0.0 4.3e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP SGIII PF15467.1 KXX73920.1 - 0.044 12.8 4.1 0.063 12.3 2.8 1.1 1 0 0 1 1 1 0 Secretogranin-3 PWWP PF00855.12 KXX73920.1 - 0.074 13.2 0.0 0.44 10.7 0.0 2.3 2 1 0 2 2 2 0 PWWP domain TMA7 PF09072.5 KXX73920.1 - 0.15 12.5 1.1 0.4 11.1 0.4 2.1 2 0 0 2 2 2 0 Translation machinery associated TMA7 KR PF08659.5 KXX73920.1 - 0.16 11.5 0.8 0.33 10.5 0.6 1.5 1 0 0 1 1 1 0 KR domain DUF724 PF05266.9 KXX73920.1 - 0.32 10.5 7.6 0.53 9.8 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF904 PF06005.7 KXX73920.1 - 0.77 10.0 11.2 4 7.8 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FlxA PF14282.1 KXX73920.1 - 1.3 9.0 16.7 6.1 6.8 11.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Tox-HNH-EHHH PF15657.1 KXX73920.1 - 1.7 8.8 5.6 1.7 8.8 0.0 2.6 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins OmpH PF03938.9 KXX73920.1 - 2.3 8.1 12.4 5.1 7.0 8.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 KXX73920.1 - 3.7 7.1 8.2 5.2 6.6 4.9 1.9 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX73920.1 - 7.8 6.0 11.9 12 5.3 8.3 1.3 1 0 0 1 1 1 0 IncA protein AA_permease PF00324.16 KXX73921.1 - 1.7e-117 392.6 43.6 2.1e-117 392.4 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX73921.1 - 3.1e-27 95.2 47.9 4.1e-27 94.7 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease Ldh_1_N PF00056.18 KXX73922.1 - 1.8e-43 147.7 0.9 3.5e-43 146.8 0.6 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KXX73922.1 - 9.4e-29 100.3 0.0 1.6e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KXX73922.1 - 1.5e-05 24.3 2.4 0.013 14.8 0.1 3.1 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 KXX73922.1 - 2e-05 24.7 0.5 0.00038 20.5 0.2 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KXX73922.1 - 0.00015 21.5 0.1 0.00027 20.7 0.1 1.6 1 0 0 1 1 1 1 ThiF family DAO PF01266.19 KXX73922.1 - 0.00037 19.5 3.1 0.00061 18.7 2.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX73922.1 - 0.00042 20.5 0.9 0.0011 19.1 0.2 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KXX73922.1 - 0.00059 19.2 0.8 0.0013 18.1 0.5 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KXX73922.1 - 0.0022 17.6 0.6 0.0056 16.3 0.4 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KXX73922.1 - 0.01 14.6 0.6 0.02 13.7 0.4 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ApbA PF02558.11 KXX73922.1 - 0.014 14.8 0.7 0.041 13.3 0.2 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KXX73922.1 - 0.016 14.3 0.1 0.033 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KXX73922.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX73922.1 - 0.034 14.2 2.0 0.06 13.4 0.6 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KXX73922.1 - 0.042 14.2 2.9 0.074 13.4 1.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KXX73922.1 - 0.05 13.6 0.6 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.1 KXX73922.1 - 0.075 13.0 0.3 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OTCace PF00185.19 KXX73922.1 - 0.097 12.5 0.1 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pyr_redox PF00070.22 KXX73922.1 - 0.099 13.0 1.4 0.22 11.9 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CFEM PF05730.6 KXX73923.1 - 0.0016 18.2 2.5 0.0026 17.5 1.7 1.3 1 0 0 1 1 1 1 CFEM domain GCS PF03074.11 KXX73924.1 - 8.6e-154 512.0 0.0 1e-151 505.2 0.0 2.1 1 1 0 1 1 1 1 Glutamate-cysteine ligase Glyco_hydro_72 PF03198.9 KXX73925.1 - 5.3e-70 235.8 1.7 9.2e-70 235.0 1.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase FCH PF00611.18 KXX73925.1 - 2.5e-22 78.8 0.0 2.5e-22 78.8 0.0 3.1 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KXX73925.1 - 3.2e-20 71.4 0.1 1e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 KXX73925.1 - 3.4e-14 52.3 5.6 3.4e-14 52.3 3.9 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KXX73925.1 - 9.3e-12 44.1 0.0 2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KXX73925.1 - 0.00034 20.0 0.1 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KXX73925.1 - 0.002 18.2 0.1 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain Cellulase PF00150.13 KXX73925.1 - 0.0044 16.2 0.3 0.049 12.8 0.2 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7TM_GPCR_Sri PF10327.4 KXX73925.1 - 0.15 10.9 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Allexi_40kDa PF05549.6 KXX73925.1 - 0.21 10.8 2.8 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein C1_2 PF03107.11 KXX73925.1 - 0.65 10.1 7.8 1.5 9.0 5.4 1.6 1 0 0 1 1 1 0 C1 domain GATA PF00320.22 KXX73926.1 - 9.9e-16 56.8 3.4 1.8e-15 55.9 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger DEAD PF00270.24 KXX73927.1 - 5.5e-33 113.8 0.2 1.1e-31 109.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX73927.1 - 3.7e-22 77.9 0.1 7.2e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX73927.1 - 0.00063 19.6 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KXX73927.1 - 0.00079 19.1 0.1 0.06 13.1 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 KXX73927.1 - 0.0072 16.2 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_30 PF13604.1 KXX73927.1 - 0.022 14.3 0.0 0.068 12.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KXX73927.1 - 0.023 14.8 1.1 1.4 9.0 0.5 2.9 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.1 KXX73927.1 - 0.046 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GCFC PF07842.7 KXX73928.1 - 9.2e-80 267.9 0.5 9.2e-80 267.9 0.4 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 KXX73928.1 - 3.9e-15 55.8 18.1 3.9e-15 55.8 12.5 2.9 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 KXX73928.1 - 3.9e-14 52.1 4.2 1.3e-13 50.5 2.9 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KXX73928.1 - 1.5e-07 31.1 3.8 1.5e-07 31.1 2.6 3.4 3 1 1 4 4 4 1 DExH-box splicing factor binding site FUSC PF04632.7 KXX73928.1 - 0.038 12.4 2.9 0.084 11.2 2.0 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop14 PF04147.7 KXX73928.1 - 1.9 6.2 25.1 0.52 8.1 8.7 2.2 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 KXX73928.1 - 7.6 4.8 16.5 0.77 8.1 5.4 2.3 2 0 0 2 2 2 0 Daxx Family Epimerase PF01370.16 KXX73929.1 - 5.4e-17 62.0 1.0 1.4e-16 60.6 0.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX73929.1 - 2.3e-15 57.0 0.1 1.1e-14 54.8 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX73929.1 - 3.8e-08 32.3 0.0 5.2e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX73929.1 - 0.0003 19.8 0.2 0.0033 16.3 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KXX73929.1 - 0.00036 20.5 0.6 0.00036 20.5 0.4 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KXX73929.1 - 0.00066 18.6 0.0 0.00098 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KXX73929.1 - 0.007 15.6 0.1 0.013 14.8 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KXX73929.1 - 0.016 14.8 0.2 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 KXX73930.1 - 6.3e-31 107.5 0.8 9.1e-31 107.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX73930.1 - 8.4e-26 91.2 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX73930.1 - 5.8e-17 61.9 0.2 8.8e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX73930.1 - 5.8e-05 23.1 0.9 0.00011 22.3 0.6 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX73930.1 - 0.0056 16.1 0.9 0.012 15.0 0.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1372 PF07116.6 KXX73930.1 - 0.042 13.8 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) THF_DHG_CYH_C PF02882.14 KXX73930.1 - 0.075 12.1 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pectinesterase PF01095.14 KXX73931.1 - 1.8e-51 174.4 2.0 2.5e-51 174.0 1.4 1.0 1 0 0 1 1 1 1 Pectinesterase DUF2345 PF10106.4 KXX73931.1 - 0.064 12.8 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) PsaM PF07465.8 KXX73931.1 - 1.5 8.4 4.0 1.7 8.3 1.1 2.2 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Lyase_aromatic PF00221.14 KXX73932.1 - 6.9e-154 512.7 6.8 9.7e-154 512.3 4.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase EF-hand_1 PF00036.27 KXX73933.1 - 1.2e-35 118.0 11.5 4.8e-09 34.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KXX73933.1 - 6.9e-33 112.5 6.0 7.2e-16 58.0 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KXX73933.1 - 5e-30 100.6 8.4 1.9e-08 33.4 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KXX73933.1 - 5.6e-29 99.5 11.7 6.3e-14 51.3 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KXX73933.1 - 1e-27 94.2 11.5 1.2e-07 30.6 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KXX73933.1 - 1.6e-16 59.9 0.1 2.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KXX73933.1 - 6.1e-11 41.9 1.4 5.9e-05 22.7 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KXX73933.1 - 1.3e-07 31.5 0.0 0.012 15.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 KXX73933.1 - 0.00012 21.8 1.0 0.2 11.3 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.5 KXX73933.1 - 0.0079 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Toprim_4 PF13662.1 KXX73933.1 - 0.012 15.5 0.5 0.085 12.8 0.0 2.4 1 1 1 2 2 2 0 Toprim domain Toprim_2 PF13155.1 KXX73933.1 - 0.029 14.7 0.4 0.89 9.9 0.0 2.2 1 1 1 2 2 2 0 Toprim-like GTPase_Cys_C PF12631.2 KXX73933.1 - 0.029 14.7 0.1 0.36 11.2 0.1 2.3 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE UPF0154 PF03672.8 KXX73933.1 - 0.068 12.8 0.0 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Toprim PF01751.17 KXX73933.1 - 0.07 13.1 0.1 0.85 9.6 0.0 2.2 1 1 1 2 2 2 0 Toprim domain DUF3164 PF11363.3 KXX73933.1 - 0.071 12.4 0.6 1.7 7.9 0.1 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3164) Caleosin PF05042.8 KXX73933.1 - 0.12 11.9 0.2 11 5.4 0.0 3.1 1 1 2 4 4 4 0 Caleosin related protein PMBR PF09373.5 KXX73933.1 - 0.13 12.2 0.0 15 5.7 0.0 3.0 2 1 0 2 2 2 0 Pseudomurein-binding repeat EF-hand_10 PF14788.1 KXX73933.1 - 0.13 11.9 3.9 0.32 10.6 0.1 3.1 1 1 4 5 5 5 0 EF hand VCBS PF13517.1 KXX73933.1 - 1.8 8.9 4.5 2.8 8.3 0.1 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HET PF06985.6 KXX73934.1 - 2.4e-05 24.5 0.0 3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1688 PF07958.6 KXX73935.1 - 3.1e-171 569.5 0.0 3.6e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GIY-YIG PF01541.19 KXX73937.1 - 2.3e-09 37.4 0.0 3.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.1 KXX73937.1 - 0.017 15.0 0.5 0.029 14.3 0.4 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 KXX73937.1 - 0.02 14.6 3.8 0.033 14.0 2.6 1.3 1 0 0 1 1 1 0 Ring finger domain T5orf172 PF10544.4 KXX73937.1 - 0.034 14.5 0.0 0.09 13.1 0.0 1.7 2 0 0 2 2 2 0 T5orf172 domain zf-HC5HC2H PF13771.1 KXX73937.1 - 0.037 14.1 0.5 0.066 13.3 0.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KXX73937.1 - 0.06 13.0 3.1 1.2 8.9 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KXX73937.1 - 0.063 13.2 1.2 0.1 12.5 0.9 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KXX73937.1 - 0.6 9.8 3.6 1.2 8.8 2.5 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KXX73937.1 - 5.7 7.0 6.1 40 4.3 4.4 2.1 1 1 0 1 1 1 0 RING-like domain PLU-1 PF08429.6 KXX73938.1 - 4.2e-107 357.9 13.9 3.2e-104 348.4 8.9 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KXX73938.1 - 1.6e-43 147.5 0.2 3.5e-43 146.4 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KXX73938.1 - 5.6e-27 93.4 0.1 1.4e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KXX73938.1 - 4.4e-17 61.5 29.8 3.7e-09 36.1 4.4 3.7 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 KXX73938.1 - 8.9e-14 50.7 0.6 2e-13 49.5 0.4 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KXX73938.1 - 2.8e-12 46.5 6.0 6.5e-12 45.3 4.1 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger Chloroplast_duf PF14476.1 KXX73938.1 - 0.53 9.0 1.8 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Petal formation-expressed C1_1 PF00130.17 KXX73938.1 - 0.63 9.8 17.1 0.3 10.8 0.3 3.0 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 KXX73938.1 - 1.2 8.4 11.0 1.3 8.2 1.1 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KXX73938.1 - 6.1 6.6 17.0 0.059 13.1 1.3 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KXX73938.1 - 8.3 5.8 11.5 0.5 9.7 0.8 2.8 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.15 KXX73938.1 - 8.9 6.2 16.7 0.095 12.5 2.0 3.2 2 1 0 2 2 2 0 Rubredoxin MFS_1 PF07690.11 KXX73939.1 - 1.1e-29 103.2 24.2 1.1e-29 103.2 16.8 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX73939.1 - 4.5e-29 101.3 22.4 5.4e-28 97.7 15.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.14 KXX73939.1 - 0.00052 18.6 9.4 0.00052 18.6 6.5 1.8 2 1 0 2 2 2 1 LacY proton/sugar symporter Peptidase_A8 PF01252.13 KXX73939.1 - 0.016 14.8 0.8 0.054 13.1 0.5 2.0 1 0 0 1 1 1 0 Signal peptidase (SPase) II PIRT PF15099.1 KXX73939.1 - 0.046 12.9 0.5 0.14 11.3 0.3 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3449 PF11931.3 KXX73940.1 - 5.6e-69 231.6 1.6 1.6e-68 230.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KXX73940.1 - 1.5e-13 50.0 1.5 1.1e-12 47.1 0.1 2.5 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 KXX73940.1 - 6.8e-11 41.9 2.1 3.1e-08 33.5 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX73940.1 - 1.4e-10 41.0 1.1 2.2e-08 34.0 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KXX73940.1 - 0.00032 20.7 2.9 0.041 13.9 0.0 3.6 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KXX73940.1 - 0.019 14.6 0.2 0.019 14.6 0.2 2.7 3 1 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.1 KXX73940.1 - 0.16 12.3 4.0 5.8 7.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger C1_2 PF03107.11 KXX73940.1 - 2.1 8.5 3.9 3 8.0 0.6 2.5 2 0 0 2 2 2 0 C1 domain DEAD PF00270.24 KXX73941.1 - 2.4e-41 141.0 0.4 6.2e-41 139.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX73941.1 - 3.8e-29 100.3 0.2 9.1e-29 99.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KXX73941.1 - 0.0091 15.3 0.5 0.016 14.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 KXX73941.1 - 0.013 15.0 0.5 0.03 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX73941.1 - 0.016 14.9 0.2 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KXX73941.1 - 0.023 14.5 0.1 0.065 13.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KXX73941.1 - 0.047 13.4 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KXX73941.1 - 0.11 12.6 1.0 0.49 10.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KXX73941.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Pkinase PF00069.20 KXX73943.1 - 3.1e-33 115.0 0.0 4.7e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73943.1 - 6.7e-20 71.2 0.0 9.6e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fringe PF02434.11 KXX73944.1 - 1.1e-07 31.3 0.6 1.1e-06 28.1 0.4 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KXX73944.1 - 0.0021 17.7 4.1 0.0062 16.2 2.8 1.7 1 0 0 1 1 1 1 PAN domain Peptidase_M28 PF04389.12 KXX73945.1 - 2.2e-36 125.2 0.0 4.8e-36 124.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KXX73945.1 - 4.8e-14 51.8 0.0 3.3e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KXX73945.1 - 9.3e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2172 PF09940.4 KXX73945.1 - 0.012 13.9 0.0 0.021 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Hemerythrin PF01814.18 KXX73946.1 - 6e-17 62.0 2.3 8.3e-17 61.5 1.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FAD_binding_7 PF03441.9 KXX73946.1 - 0.0015 17.7 0.5 0.002 17.3 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DUF445 PF04286.7 KXX73946.1 - 0.62 9.5 3.0 3.8 6.9 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) p450 PF00067.17 KXX73947.1 - 8e-51 172.9 0.0 1.1e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2196 PF09962.4 KXX73948.1 - 2.9e-22 78.2 1.5 4.8e-22 77.4 1.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Prp31_C PF09785.4 KXX73950.1 - 2.6e-43 147.4 0.9 6.4e-43 146.1 0.6 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KXX73950.1 - 1.2e-39 135.0 0.1 2.2e-39 134.1 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KXX73950.1 - 3.8e-23 81.0 0.1 5.1e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain TPR_14 PF13428.1 KXX73952.1 - 9.6e-26 87.9 27.3 1e-05 25.7 0.1 12.3 8 2 6 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 KXX73952.1 - 7.4e-25 87.0 2.4 2.9e-07 30.7 0.0 7.8 7 1 0 8 8 8 4 Tetratricopeptide repeat HAT PF02184.11 KXX73952.1 - 7.8e-24 83.1 60.7 4.6e-10 39.0 1.0 12.6 13 0 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KXX73952.1 - 8.1e-19 67.7 22.1 0.0014 19.2 0.0 9.2 6 4 2 10 10 9 5 Tetratricopeptide repeat Suf PF05843.9 KXX73952.1 - 2.2e-17 63.7 9.0 1.5e-05 24.8 0.0 6.5 3 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KXX73952.1 - 1.7e-10 40.4 10.0 0.00015 20.9 0.7 5.6 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX73952.1 - 1.7e-07 31.0 15.3 2.3 8.2 0.0 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX73952.1 - 5.3e-07 29.1 8.4 0.023 14.3 0.1 5.9 7 0 0 7 7 6 2 TPR repeat TPR_6 PF13174.1 KXX73952.1 - 1e-06 28.7 17.6 0.18 12.3 0.0 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX73952.1 - 1.3e-06 28.1 4.2 0.47 10.3 0.0 5.7 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KXX73952.1 - 0.00013 21.6 23.7 0.0076 16.0 0.1 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX73952.1 - 0.00017 21.5 13.7 0.18 12.1 0.0 7.1 9 0 0 9 9 6 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KXX73952.1 - 0.00059 19.5 15.2 0.055 13.2 1.2 5.7 3 2 1 5 5 5 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.1 KXX73952.1 - 0.00086 19.1 3.6 1.8 8.4 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX73952.1 - 0.0021 17.7 10.1 14 5.8 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX73952.1 - 0.0025 17.4 0.0 35 4.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 KXX73952.1 - 0.095 12.8 3.0 1.9 8.6 0.1 3.8 3 0 0 3 3 3 0 c-SKI Smad4 binding domain TPR_1 PF00515.23 KXX73952.1 - 0.16 11.6 4.9 3.1 7.5 0.0 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Spore_III_AB PF09548.5 KXX73952.1 - 0.19 11.4 0.8 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) NRDE-2 PF08424.5 KXX73952.1 - 8.6 5.1 31.5 0.53 9.1 0.1 5.7 5 1 1 6 6 6 0 NRDE-2, necessary for RNA interference Glyco_tranf_2_3 PF13641.1 KXX73954.1 - 2.2e-12 47.2 0.2 4e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KXX73954.1 - 2.3e-09 37.2 9.4 9.9e-09 35.1 6.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KXX73954.1 - 2.6e-09 36.5 0.1 5.3e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KXX73954.1 - 3.3e-06 25.7 0.4 7.1e-05 21.3 0.3 2.3 1 1 0 1 1 1 1 Chitin synthase HRXXH PF13933.1 KXX73955.1 - 1.6e-68 230.7 0.2 1.8e-68 230.6 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family HCV_NS5a_1a PF08300.8 KXX73955.1 - 0.042 13.7 0.4 0.08 12.8 0.3 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain MVL PF12151.3 KXX73955.1 - 0.75 9.5 4.1 1.7 8.3 2.8 1.6 1 1 0 1 1 1 0 Mannan-binding protein DUF423 PF04241.10 KXX73956.1 - 8.9e-18 64.0 3.7 8.1e-17 60.9 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF423) Trep_Strep PF09605.5 KXX73956.1 - 0.089 12.4 0.4 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Zn_clus PF00172.13 KXX73957.1 - 1.3e-08 34.6 8.5 2e-08 34.0 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX73957.1 - 5.4e-08 31.8 6.6 9.4e-08 31.0 3.6 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_6 PF01341.12 KXX73958.1 - 3.6e-88 295.8 0.1 4e-88 295.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 GTP_cyclohydro2 PF00925.15 KXX73959.1 - 7.8e-57 191.1 0.1 1.6e-51 173.9 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II REV PF00424.13 KXX73960.1 - 0.04 13.8 5.5 0.23 11.3 1.4 3.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Ribosomal_S24e PF01282.14 KXX73961.1 - 8.4e-37 124.8 0.0 1.3e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Abhydrolase_4 PF08386.5 KXX73962.1 - 6.7e-23 80.5 0.0 1.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX73962.1 - 1.2e-16 60.9 0.0 3.8e-15 56.0 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX73962.1 - 2.6e-10 40.5 0.7 5.3e-09 36.2 0.5 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family HEAT_PBS PF03130.11 KXX73962.1 - 0.097 13.1 0.1 1.3 9.7 0.0 2.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat SDF PF00375.13 KXX73963.1 - 4.6e-88 295.5 34.0 5.8e-88 295.2 23.6 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 KXX73963.1 - 0.065 12.8 3.4 0.065 12.8 0.0 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase FMN_dh PF01070.13 KXX73965.1 - 0.029 13.2 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Methyltransf_16 PF10294.4 KXX73966.1 - 4e-17 62.2 0.0 6.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KXX73966.1 - 2.8e-07 31.1 0.0 4.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KXX73966.1 - 0.00026 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KXX73966.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KXX73966.1 - 0.0026 16.9 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KXX73966.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX73966.1 - 0.0048 16.9 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX73966.1 - 0.0056 16.4 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KXX73966.1 - 0.0089 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 KXX73966.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 KXX73966.1 - 0.033 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ADH_zinc_N PF00107.21 KXX73966.1 - 0.039 13.5 0.1 0.72 9.4 0.0 2.4 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KXX73966.1 - 0.061 13.8 0.1 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KXX73966.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mad3_BUB1_I PF08311.7 KXX73967.1 - 4.4e-44 149.2 0.4 1.5e-43 147.5 0.3 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KXX73967.1 - 7.4e-12 44.9 0.0 2.1e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX73967.1 - 0.005 15.9 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase AP_endonuc_2 PF01261.19 KXX73968.1 - 2.9e-30 105.1 0.1 4.3e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SNARE_assoc PF09335.6 KXX73970.1 - 3.1e-12 46.7 8.6 3.1e-12 46.7 5.9 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF1771 PF08590.5 KXX73971.1 - 2.1e-14 53.2 11.2 5.9e-14 51.8 7.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KXX73971.1 - 1e-09 38.4 0.0 4.3e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KXX73971.1 - 7.5e-07 28.6 1.7 0.0035 16.9 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KXX73971.1 - 0.007 16.4 0.2 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 HBS1 N-terminus PAM2 PF07145.10 KXX73971.1 - 0.063 12.8 0.0 0.063 12.8 0.0 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Cupin_8 PF13621.1 KXX73972.1 - 3.6e-20 72.5 0.0 1.4e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KXX73972.1 - 1.7e-10 41.1 0.0 3.7e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KXX73972.1 - 0.00043 19.9 0.1 0.00092 18.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 KXX73972.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein RRM_1 PF00076.17 KXX73973.1 - 3.7e-17 61.7 0.0 8.1e-17 60.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX73973.1 - 5.9e-12 45.3 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX73973.1 - 7.7e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KXX73973.1 - 1.7e-05 25.1 11.0 1.7e-05 25.1 7.7 4.1 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 F-box-like PF12937.2 KXX73974.1 - 0.00012 21.6 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 KXX73974.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) DEAD PF00270.24 KXX73976.1 - 7.1e-44 149.2 2.5 8.9e-44 148.9 1.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX73976.1 - 1.2e-27 95.5 0.3 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX73976.1 - 0.0016 18.3 0.0 0.0036 17.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KXX73976.1 - 0.0029 17.2 0.2 0.0085 15.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX73976.1 - 0.013 15.6 0.0 0.039 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX73976.1 - 0.03 14.0 0.1 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 KXX73976.1 - 0.032 13.2 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 KXX73976.1 - 0.074 12.3 0.1 0.11 11.7 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.20 KXX73976.1 - 0.077 12.1 0.3 0.29 10.2 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 KXX73976.1 - 0.083 12.6 0.1 0.38 10.4 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 KXX73976.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Stb3 PF10330.4 KXX73978.1 - 1.3e-37 127.3 0.0 2e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 KXX73979.1 - 1.8e-93 313.5 0.0 3.7e-88 296.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KXX73979.1 - 1.8e-19 69.5 0.0 3.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4149 PF13664.1 KXX73981.1 - 1.3e-22 79.7 2.2 1.3e-22 79.7 1.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF3816 PF12822.2 KXX73981.1 - 0.012 15.4 2.4 0.018 14.9 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF21 PF01595.15 KXX73981.1 - 0.42 9.8 2.8 0.95 8.7 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF21 HET PF06985.6 KXX73982.1 - 2.1e-29 102.4 0.0 3.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ku PF02735.11 KXX73983.1 - 1.8e-27 96.0 0.0 3.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KXX73983.1 - 2e-24 86.2 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KXX73983.1 - 4e-15 55.7 0.0 7.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KXX73983.1 - 0.00018 21.6 0.0 0.00062 19.9 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX73983.1 - 0.0057 16.4 0.1 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1295 PF06966.7 KXX73984.1 - 1.2e-37 129.4 7.9 1.5e-37 129.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DnaJ PF00226.26 KXX73985.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KXX73985.1 - 6e-06 26.0 0.0 7.3e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Pam16 Abhydrolase_6 PF12697.2 KXX73987.1 - 9.8e-15 55.0 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX73987.1 - 1.5e-07 31.2 0.0 2.6e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX73987.1 - 0.11 12.3 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase eRF1_1 PF03463.10 KXX73988.1 - 2.6e-28 98.2 0.1 4.9e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KXX73988.1 - 4.2e-23 82.1 0.0 6.9e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KXX73988.1 - 1.6e-18 66.9 0.1 4.1e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 3 Methyltransf_11 PF08241.7 KXX73989.1 - 6.5e-17 61.8 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX73989.1 - 6.3e-16 58.5 0.0 9.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX73989.1 - 2.6e-13 50.5 0.0 4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX73989.1 - 1.7e-12 47.6 0.0 3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX73989.1 - 3.2e-12 46.5 0.1 4.9e-12 45.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX73989.1 - 2.2e-11 43.7 0.0 3.5e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX73989.1 - 3.2e-10 39.8 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KXX73989.1 - 1.6e-06 27.6 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.13 KXX73989.1 - 2.6e-06 26.7 0.0 4.8e-06 25.8 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX73989.1 - 3.2e-06 26.6 0.0 5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KXX73989.1 - 7.9e-06 25.3 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KXX73989.1 - 0.00019 20.5 0.0 0.00025 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KXX73989.1 - 0.00033 19.8 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 KXX73989.1 - 0.00059 19.1 0.0 0.016 14.5 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.13 KXX73989.1 - 0.035 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TehB PF03848.9 KXX73989.1 - 0.066 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 KXX73989.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KXX73989.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF4246 PF14033.1 KXX73990.1 - 1.4e-170 568.2 0.5 1.7e-170 567.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WSC PF01822.14 KXX73991.1 - 1.1e-39 134.2 21.6 8.7e-20 70.4 4.5 2.1 2 0 0 2 2 2 2 WSC domain Thioredoxin PF00085.15 KXX73992.1 - 6.7e-22 77.1 0.0 9.9e-22 76.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX73992.1 - 1.8e-06 27.9 0.0 9e-06 25.7 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KXX73992.1 - 1.2e-05 25.0 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KXX73992.1 - 0.00015 21.9 0.1 0.0039 17.3 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KXX73992.1 - 0.00016 21.2 0.0 0.00048 19.6 0.0 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 KXX73992.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KXX73992.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.1 KXX73992.1 - 0.024 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 KXX73992.1 - 0.037 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.19 KXX73992.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin BCS1_N PF08740.6 KXX73993.1 - 1.9e-38 131.9 1.1 1.9e-38 131.9 0.7 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KXX73993.1 - 3.2e-19 69.4 0.1 8.5e-18 64.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX73993.1 - 2.2e-05 25.2 0.5 0.0003 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KXX73993.1 - 5.4e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX73993.1 - 0.00022 21.2 0.1 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KXX73993.1 - 0.0022 17.4 0.0 0.0069 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KXX73993.1 - 0.0036 16.7 0.0 0.014 14.8 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KXX73993.1 - 0.0036 17.0 0.0 0.013 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX73993.1 - 0.0062 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KXX73993.1 - 0.0081 15.1 0.0 0.023 13.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KXX73993.1 - 0.012 15.7 0.1 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KXX73993.1 - 0.017 14.6 0.2 0.05 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KXX73993.1 - 0.027 14.0 5.0 0.15 11.6 3.5 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KXX73993.1 - 0.028 13.5 1.3 0.089 11.8 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.1 KXX73993.1 - 0.033 14.0 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KXX73993.1 - 0.033 14.4 3.7 0.056 13.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KXX73993.1 - 3.2 8.0 8.8 21 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KXX73993.1 - 4.7 5.5 13.5 6.5 5.0 0.2 2.1 2 0 0 2 2 2 0 AAA domain Amidoligase_2 PF12224.3 KXX73994.1 - 5e-18 65.6 0.0 5.4e-17 62.2 0.0 2.3 1 1 0 1 1 1 1 Putative amidoligase enzyme HGTP_anticodon PF03129.15 KXX73994.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain WD40 PF00400.27 KXX73995.1 - 5.4e-34 114.8 5.6 4.2e-10 39.0 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Zn_Tnp_IS1595 PF12760.2 KXX73995.1 - 0.018 14.8 1.4 0.04 13.7 1.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PD40 PF07676.7 KXX73995.1 - 0.029 14.0 0.0 48 3.7 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KXX73995.1 - 0.09 10.5 0.0 2.7 5.7 0.0 2.0 1 1 1 2 2 2 0 IKI3 family Nup160 PF11715.3 KXX73995.1 - 0.13 10.3 5.4 2.8 5.9 0.3 4.0 3 1 0 4 4 4 0 Nucleoporin Nup120/160 Aldo_ket_red PF00248.16 KXX73996.1 - 1.8e-42 145.1 0.0 2.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Dabb PF07876.7 KXX73997.1 - 4.7e-26 91.0 0.1 6e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2461 PF09365.5 KXX73997.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Mito_fiss_reg PF05308.6 KXX73999.1 - 0.042 13.2 19.7 0.076 12.3 13.6 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Pex14_N PF04695.8 KXX73999.1 - 0.68 9.9 10.8 1 9.4 7.5 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.4 KXX73999.1 - 0.8 8.2 8.6 1 7.9 5.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ECH PF00378.15 KXX74000.1 - 3.1e-39 134.5 0.6 4.6e-39 134.0 0.4 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TIM-br_sig_trns PF09370.5 KXX74000.1 - 0.0048 16.0 0.1 0.0089 15.1 0.1 1.4 1 0 0 1 1 1 1 TIM-barrel signal transduction protein ECH_C PF13766.1 KXX74000.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region AMP-binding PF00501.23 KXX74001.1 - 6.3e-81 271.8 0.0 8.3e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX74001.1 - 2.8e-10 40.9 0.0 7.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tbf5 PF06331.7 KXX74002.1 - 6.5e-28 96.3 0.8 7.1e-28 96.1 0.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 NAD_binding_5 PF07994.7 KXX74003.1 - 3e-113 378.2 0.1 4.3e-113 377.6 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KXX74003.1 - 3.9e-46 155.5 0.4 7.4e-46 154.5 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FNIP_C PF14638.1 KXX74003.1 - 0.025 13.9 0.1 0.63 9.3 0.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus MFS_1 PF07690.11 KXX74004.1 - 1.9e-33 115.6 61.9 6.2e-30 104.0 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74004.1 - 2.8e-23 82.2 23.9 8.9e-23 80.5 16.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 KXX74004.1 - 0.11 12.4 0.2 0.11 12.4 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Pectate_lyase_3 PF12708.2 KXX74005.1 - 5.1e-46 157.6 7.3 1.3e-37 130.0 1.6 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.1 KXX74005.1 - 1.3e-06 28.2 2.9 9.4e-06 25.4 2.3 2.1 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 KXX74005.1 - 1.2e-05 24.6 0.5 3.1e-05 23.2 0.3 1.7 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.12 KXX74005.1 - 0.18 10.2 0.7 0.28 9.6 0.5 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DnaJ PF00226.26 KXX74006.1 - 3.7e-12 45.8 0.0 5.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ran_BP1 PF00638.13 KXX74007.1 - 5e-13 49.1 0.0 4.1e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain Nucleoporin_FG PF13634.1 KXX74007.1 - 1.7e-10 41.1 114.0 3.3e-06 27.2 22.2 10.1 2 2 5 7 7 7 3 Nucleoporin FG repeat region SCP2 PF02036.12 KXX74008.1 - 3.8e-24 84.9 0.6 4.8e-24 84.5 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KXX74008.1 - 2.7e-07 30.5 0.2 3.5e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal BTB PF00651.26 KXX74011.1 - 0.0043 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.1 KXX74012.1 - 8.1e-19 67.8 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74012.1 - 2.1e-16 60.1 0.0 3.1e-15 56.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74012.1 - 5.9e-14 52.5 0.0 1.8e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74012.1 - 6.5e-14 52.2 0.0 6.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74012.1 - 1.6e-13 50.5 0.0 9.4e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74012.1 - 4.1e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX74012.1 - 7.5e-05 21.9 0.1 0.086 11.9 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX74012.1 - 9.2e-05 21.8 0.0 0.0003 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX74012.1 - 0.00014 21.8 2.9 0.00039 20.4 0.2 2.4 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 KXX74012.1 - 0.0011 17.9 0.0 0.043 12.6 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase RrnaAD PF00398.15 KXX74012.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KXX74012.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 KXX74012.1 - 0.0072 15.4 0.0 0.057 12.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KXX74012.1 - 0.0085 15.4 0.0 0.69 9.2 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.6 KXX74012.1 - 0.029 13.0 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.4 KXX74012.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_16 PF00722.16 KXX74013.1 - 2.7e-16 59.4 0.2 7e-16 58.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KXX74013.1 - 2.1e-06 26.2 8.0 0.00088 17.5 0.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.4 KXX74013.1 - 0.009 15.5 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) Glyco_hydro_10 PF00331.15 KXX74015.1 - 7.7e-96 320.8 0.0 9e-96 320.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KXX74015.1 - 3e-14 52.3 10.2 6.9e-14 51.2 7.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain AA_permease PF00324.16 KXX74016.1 - 6.2e-121 404.0 43.1 7.3e-121 403.8 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX74016.1 - 2.3e-31 108.7 47.0 3.2e-31 108.3 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3129 PF11327.3 KXX74017.1 - 6.5e-67 224.9 8.0 1.1e-66 224.2 5.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) TPR_18 PF13512.1 KXX74018.1 - 0.047 13.7 1.0 0.13 12.2 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 KXX74020.1 - 4.6e-14 52.6 1.3 4.5e-13 49.4 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX74020.1 - 1.4e-06 28.1 0.2 5.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KXX74020.1 - 0.022 14.5 0.0 0.43 10.2 0.0 2.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KXX74021.1 - 3e-39 134.8 0.0 4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_6 PF01341.12 KXX74022.1 - 1.4e-103 346.4 0.1 1.7e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KXX74022.1 - 4.4e-15 55.0 15.3 1.1e-14 53.7 10.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KXX74022.1 - 0.041 13.9 5.4 0.11 12.5 3.8 1.7 1 0 0 1 1 1 0 Toxin 7 GST_N PF02798.15 KXX74023.1 - 0.00017 21.7 0.1 0.0016 18.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX74023.1 - 0.0022 18.1 0.2 0.17 12.1 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PLDc_2 PF13091.1 KXX74024.1 - 1.6e-20 73.1 0.0 1.3e-12 47.5 0.0 2.7 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KXX74024.1 - 6.1e-05 22.6 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif SpoIIE PF07228.7 KXX74024.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) ThuA PF06283.6 KXX74025.1 - 2.2e-61 207.3 0.0 2.5e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 KXX74025.1 - 0.00082 18.7 0.0 0.0029 16.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1355) DUF2183 PF09949.4 KXX74026.1 - 2.6e-30 104.3 0.0 6.5e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) UvdE PF03851.9 KXX74027.1 - 1e-115 385.5 0.0 1.3e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE CysG_dimeriser PF10414.4 KXX74028.1 - 1.6 8.2 4.2 5.8 6.4 2.9 1.9 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Pkr1 PF08636.5 KXX74029.1 - 5e-36 122.6 2.5 6.9e-36 122.1 1.7 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.8 KXX74029.1 - 0.1 12.9 0.4 0.53 10.6 0.2 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEM171 PF15471.1 KXX74029.1 - 0.53 9.0 3.3 9.6 4.8 1.9 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 CBF PF03914.12 KXX74031.1 - 9.4e-45 151.9 0.0 2.2e-44 150.8 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family DegT_DnrJ_EryC1 PF01041.12 KXX74031.1 - 0.046 12.7 0.0 0.092 11.7 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.16 KXX74032.1 - 1.1e-09 38.1 14.3 1.1e-08 34.9 7.6 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KXX74032.1 - 1.8e-07 31.3 11.1 5.3e-07 29.8 7.7 1.8 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KXX74032.1 - 5.4e-06 26.1 10.3 3.7e-05 23.4 6.7 2.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF445 PF04286.7 KXX74032.1 - 0.002 17.7 3.7 0.18 11.3 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Endotoxin_N PF03945.9 KXX74032.1 - 0.056 12.8 4.3 0.1 11.9 3.0 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF1664 PF07889.7 KXX74032.1 - 0.076 12.8 6.0 0.19 11.5 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 KXX74032.1 - 0.14 11.3 8.3 0.25 10.4 5.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 KXX74032.1 - 0.32 9.3 10.6 0.47 8.8 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KXX74032.1 - 0.37 10.3 12.1 1 8.8 8.4 1.7 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KXX74032.1 - 3.1 6.7 12.4 6 5.8 8.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KXX74032.1 - 6.2 4.5 8.1 9.1 3.9 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mt_ATP-synt_B PF05405.9 KXX74033.1 - 3.8e-55 185.7 10.6 4.8e-55 185.4 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.14 KXX74033.1 - 0.22 10.9 3.4 0.22 10.9 1.4 1.6 1 1 0 1 1 1 0 Replication initiation factor Orthopox_A5L PF06193.6 KXX74033.1 - 0.96 9.3 6.7 0.3 11.0 1.3 2.4 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like LSM PF01423.17 KXX74034.1 - 4.1e-15 55.0 0.0 5.3e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KXX74034.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 KXX74034.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Methyltransf_26 PF13659.1 KXX74035.1 - 1.1e-15 57.6 1.5 2.3e-15 56.6 1.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX74035.1 - 0.074 12.4 0.0 0.36 10.1 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase small domain DUF1269 PF06897.7 KXX74035.1 - 0.43 10.6 3.0 2.1 8.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1269) Gly-zipper_OmpA PF13436.1 KXX74035.1 - 1.6 8.3 14.1 3 7.5 9.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MARVEL PF01284.18 KXX74037.1 - 1.7e-07 31.1 17.1 2.7e-07 30.5 11.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KXX74037.1 - 0.033 13.8 21.0 0.028 14.1 10.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF3708 PF12501.3 KXX74037.1 - 1 9.1 6.9 2.4 8.0 4.8 1.7 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF2697 PF10906.3 KXX74039.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) DUF4129 PF13559.1 KXX74039.1 - 0.058 13.3 0.2 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) AAA_16 PF13191.1 KXX74040.1 - 9.2e-07 29.0 0.0 2.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX74040.1 - 0.00013 22.1 0.0 0.0019 18.3 0.0 2.9 3 1 1 4 4 4 1 AAA domain Abhydrolase_6 PF12697.2 KXX74040.1 - 0.00051 19.9 0.3 0.0094 15.8 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.7 KXX74040.1 - 0.00078 19.1 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KXX74040.1 - 0.043 13.5 0.2 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family RNA_helicase PF00910.17 KXX74040.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KXX74040.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF3089 PF11288.3 KXX74040.1 - 0.16 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Glyco_transf_90 PF05686.7 KXX74041.1 - 1.2e-13 50.5 1.5 3.2e-10 39.2 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 Arginase PF00491.16 KXX74042.1 - 5.6e-77 258.7 0.3 6.7e-77 258.5 0.2 1.0 1 0 0 1 1 1 1 Arginase family zf-tcix PF14952.1 KXX74044.1 - 0.35 10.2 1.5 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding NmrA PF05368.8 KXX74045.1 - 1e-10 41.3 0.0 1.4e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 KXX74045.1 - 0.14 12.2 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.1 KXX74046.1 - 1.7e-18 66.8 0.0 2.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74046.1 - 9.5e-13 48.4 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74046.1 - 1.5e-09 38.2 0.0 9.4e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74046.1 - 3.5e-09 37.2 0.0 8.6e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74046.1 - 6.1e-07 29.1 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 KXX74046.1 - 3.3e-05 23.1 0.0 0.00029 20.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX74046.1 - 0.00015 22.0 0.0 0.00046 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX74046.1 - 0.00032 20.7 0.0 0.0063 16.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KXX74046.1 - 0.0084 15.5 0.0 0.22 10.8 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KXX74046.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.7 KXX74046.1 - 0.029 13.6 0.1 0.06 12.6 0.0 1.5 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase FtsJ PF01728.14 KXX74046.1 - 0.066 13.2 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KXX74046.1 - 0.087 11.9 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1996 PF09362.5 KXX74047.1 - 4.4e-80 268.7 0.1 5.2e-80 268.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DeoC PF01791.4 KXX74048.1 - 2.6e-41 141.4 1.2 4.2e-41 140.8 0.8 1.3 1 1 0 1 1 1 1 DeoC/LacD family aldolase Glu_synthase PF01645.12 KXX74048.1 - 0.089 11.6 0.2 0.47 9.3 0.0 2.0 2 0 0 2 2 2 0 Conserved region in glutamate synthase HET PF06985.6 KXX74049.1 - 3e-23 82.5 0.0 6.3e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ammonium_transp PF00909.16 KXX74050.1 - 7.7e-119 396.7 26.0 8.8e-119 396.5 18.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Con-6 PF10346.4 KXX74051.1 - 3.2e-14 52.0 0.3 6e-14 51.1 0.2 1.5 1 0 0 1 1 1 1 Conidiation protein 6 Toxin_52 PF15605.1 KXX74051.1 - 0.066 13.1 0.3 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Putative toxin 52 MAT1 PF06391.8 KXX74051.1 - 0.12 11.9 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Clr5 PF14420.1 KXX74053.1 - 2.9e-05 23.8 2.1 6.4e-05 22.7 1.5 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KXX74053.1 - 0.18 11.7 1.2 0.6 10.0 0.0 2.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FCH PF00611.18 KXX74054.1 - 9.9e-24 83.3 0.0 2.7e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TAFH PF07531.9 KXX74054.1 - 0.0077 15.8 0.1 0.043 13.4 0.0 1.9 2 0 0 2 2 2 1 NHR1 homology to TAF P4Ha_N PF08336.6 KXX74054.1 - 0.016 14.9 0.3 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Vps5 PF09325.5 KXX74054.1 - 0.025 13.8 0.6 0.029 13.6 0.4 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF2120 PF09893.4 KXX74054.1 - 0.048 13.6 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4075 PF13294.1 KXX74054.1 - 0.068 13.2 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF4061 PF13270.1 KXX74054.1 - 0.14 12.2 0.8 0.24 11.5 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) HALZ PF02183.13 KXX74054.1 - 0.23 11.2 2.0 0.98 9.1 0.0 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper WD40 PF00400.27 KXX74056.1 - 8.6e-56 183.9 15.0 6e-16 57.6 0.2 5.0 4 1 0 4 4 4 4 WD domain, G-beta repeat Gmad1 PF10647.4 KXX74056.1 - 0.0006 19.2 0.1 1 8.7 0.0 3.1 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 KXX74056.1 - 0.00076 19.0 2.8 1.3 8.7 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat SRP9-21 PF05486.7 KXX74056.1 - 0.028 14.1 0.0 63 3.4 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) SWIM PF04434.12 KXX74056.1 - 0.05 13.0 0.1 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 SWIM zinc finger NACHT PF05729.7 KXX74057.1 - 6.1e-24 84.5 0.2 1.3e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 NACHT domain ssDNA-exonuc_C PF10141.4 KXX74057.1 - 0.0063 16.0 0.4 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 Single-strand DNA-specific exonuclease, C terminal domain AAA_19 PF13245.1 KXX74057.1 - 0.019 14.6 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Not1 PF04054.10 KXX74058.1 - 1e-107 360.2 0.0 2.9e-107 358.8 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KXX74058.1 - 9.9e-50 168.0 0.6 3.3e-49 166.3 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Euplotes_phero PF05842.6 KXX74058.1 - 1.3 9.3 0.0 2.8 8.3 0.0 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein UPF0029 PF01205.14 KXX74059.1 - 5.6e-24 83.9 0.0 1.1e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.1 KXX74060.1 - 3.4e-11 43.1 0.0 6.7e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74060.1 - 0.013 16.0 0.0 0.071 13.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74060.1 - 0.015 15.7 0.0 2.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain AflR PF08493.5 KXX74060.1 - 4 6.4 18.4 3.5 6.5 3.4 2.2 2 0 0 2 2 2 0 Aflatoxin regulatory protein RasGAP PF00616.14 KXX74061.1 - 2.6e-46 157.7 0.1 5.1e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KXX74061.1 - 7.3e-10 38.9 0.1 1.7e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_N PF03159.13 KXX74062.1 - 6e-109 362.9 0.0 8.9e-109 362.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.9 KXX74063.1 - 5.4e-112 373.5 0.0 9.8e-112 372.7 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KXX74063.1 - 1.4e-10 41.2 25.3 1.4e-10 41.2 17.5 3.7 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT PF02985.17 KXX74063.1 - 0.11 12.6 1.7 9.9 6.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat DUF3584 PF12128.3 KXX74063.1 - 0.24 8.6 43.8 0.38 8.0 30.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AHS1 PF02682.11 KXX74063.1 - 2.8 7.3 6.1 7.4 5.9 4.2 1.7 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Spc7 PF08317.6 KXX74063.1 - 3.3 6.2 37.0 0.9 8.1 1.3 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.6 KXX74063.1 - 4.7 6.9 42.2 1.8 8.3 14.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PrmA PF06325.8 KXX74064.1 - 9.3e-11 41.3 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KXX74064.1 - 1.1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74064.1 - 1.3e-09 38.6 0.3 7.4e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74064.1 - 2e-09 37.8 0.0 6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX74064.1 - 2e-08 34.2 0.0 4.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX74064.1 - 5.9e-07 29.0 0.2 1.1e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KXX74064.1 - 7.9e-06 25.6 0.0 2.9e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74064.1 - 1.7e-05 25.0 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX74064.1 - 0.00044 19.4 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KXX74064.1 - 0.00045 20.6 0.2 0.0017 18.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 KXX74064.1 - 0.0027 17.3 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 KXX74064.1 - 0.0037 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PRMT5 PF05185.11 KXX74064.1 - 0.0056 15.6 0.0 0.0097 14.8 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 KXX74064.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KXX74064.1 - 0.012 15.5 0.1 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 KXX74064.1 - 0.028 15.2 0.0 0.12 13.1 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 KXX74064.1 - 0.052 12.2 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 KXX74064.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Med21 PF11221.3 KXX74064.1 - 0.12 12.3 0.3 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex OPT PF03169.10 KXX74065.1 - 1.1e-149 499.7 24.8 1.6e-149 499.2 17.2 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 KXX74065.1 - 0.013 15.5 0.5 0.013 15.5 0.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Rick_17kDa_Anti PF05433.10 KXX74065.1 - 4.1 7.1 13.6 0.59 9.8 0.5 3.5 3 0 0 3 3 3 0 Glycine zipper 2TM domain Rav1p_C PF12234.3 KXX74066.1 - 1e-266 886.1 0.0 1.2e-266 885.9 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Zds_C PF08632.5 KXX74067.1 - 5e-31 105.8 0.7 8.8e-31 105.0 0.5 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Nucleo_P87 PF07267.6 KXX74067.1 - 1.9 7.0 8.9 4 6.0 6.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2433 PF10360.4 KXX74068.1 - 3.1e-55 186.0 0.0 4.8e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KXX74068.1 - 0.00012 22.3 6.3 0.0035 17.6 4.4 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 KXX74068.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX74068.1 - 0.021 14.2 0.0 0.047 13.0 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PRCC PF10253.4 KXX74068.1 - 0.29 11.7 2.7 0.68 10.5 1.9 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PAT1 PF09770.4 KXX74068.1 - 5.5 5.1 10.4 8.1 4.5 7.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Smr PF01713.16 KXX74069.1 - 2.1e-12 47.0 0.1 4.9e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 KXX74069.1 - 0.00096 18.5 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain Amidase PF01425.16 KXX74070.1 - 9.7e-78 261.9 0.0 1.3e-77 261.5 0.0 1.1 1 0 0 1 1 1 1 Amidase CN_hydrolase PF00795.17 KXX74071.1 - 1.1e-22 80.2 0.0 4.2e-22 78.4 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Aha1_N PF09229.6 KXX74072.1 - 2.6e-38 130.9 0.9 4e-38 130.3 0.6 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KXX74072.1 - 2.5e-19 69.6 1.1 4.8e-19 68.6 0.4 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Patched PF02460.13 KXX74073.1 - 3.9e-74 250.0 12.8 1.8e-73 247.8 8.8 1.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KXX74073.1 - 3.4e-49 166.2 7.8 3.4e-49 166.2 5.4 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KXX74073.1 - 6.1e-05 21.8 31.7 0.001 17.8 6.3 2.5 2 0 0 2 2 2 2 MMPL family p450 PF00067.17 KXX74074.1 - 4.4e-36 124.3 0.0 8e-36 123.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX74075.1 - 1.8e-54 184.9 0.0 1.4e-53 182.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.19 KXX74076.1 - 3.1e-36 125.0 0.2 3.9e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase p450 PF00067.17 KXX74077.1 - 3.3e-28 98.4 0.0 3.7e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nse5 PF08691.5 KXX74078.1 - 0.0052 15.3 0.0 0.0065 15.0 0.0 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 MFS_1 PF07690.11 KXX74079.1 - 8.1e-19 67.5 29.1 8.1e-19 67.5 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_T PF00929.19 KXX74080.1 - 3e-09 37.3 0.0 2.5e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Exonuclease BRO1 PF03097.13 KXX74081.1 - 4.3e-114 381.1 0.3 4.3e-114 381.1 0.2 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KXX74081.1 - 8.2e-80 267.9 1.2 8.2e-80 267.9 0.8 1.9 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF1421 PF07223.6 KXX74081.1 - 0.0034 17.2 11.4 0.0053 16.5 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1421) K-box PF01486.12 KXX74081.1 - 0.03 14.0 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 K-box region p450 PF00067.17 KXX74082.1 - 1.2e-31 109.7 0.0 1.8e-30 105.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Fer4_5 PF12801.2 KXX74083.1 - 0.062 13.1 0.5 0.062 13.1 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain TMEM52 PF14979.1 KXX74083.1 - 0.54 10.1 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane 52 Amidase PF01425.16 KXX74084.1 - 7.4e-33 114.0 0.9 1e-31 110.2 0.4 2.1 2 0 0 2 2 2 2 Amidase NAD_binding_6 PF08030.7 KXX74085.1 - 4.4e-19 68.9 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KXX74085.1 - 1e-18 67.6 15.0 1e-18 67.6 10.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KXX74085.1 - 8e-10 38.5 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KXX74085.1 - 1.4e-05 25.6 0.0 3.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4018 PF13210.1 KXX74085.1 - 0.73 9.1 7.1 1.6 8.0 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) VIT1 PF01988.14 KXX74085.1 - 1.4 8.4 6.7 1.5 8.2 0.6 3.0 3 0 0 3 3 3 0 VIT family Peptidase_S28 PF05577.7 KXX74086.1 - 7e-45 153.3 0.0 2e-44 151.8 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KXX74086.1 - 0.035 13.9 0.1 0.061 13.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family 3Beta_HSD PF01073.14 KXX74087.1 - 8.7e-27 93.5 0.0 6e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX74087.1 - 3.6e-14 52.7 0.0 7.3e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX74087.1 - 7.7e-09 34.8 0.0 4.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KXX74087.1 - 1.6e-07 31.5 0.0 1.7e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX74087.1 - 2.9e-05 24.0 0.9 7.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KXX74087.1 - 7.7e-05 21.7 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KXX74087.1 - 0.0022 17.7 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Ctr PF04145.10 KXX74088.1 - 6.7e-43 146.1 0.2 8.6e-43 145.8 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TauE PF01925.14 KXX74088.1 - 0.0086 15.5 4.9 0.032 13.6 3.2 1.9 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Fungal_trans_2 PF11951.3 KXX74089.1 - 1.6e-10 40.1 0.2 2e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 KXX74090.1 - 3e-07 30.2 0.1 9.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KXX74090.1 - 0.0004 20.5 0.0 0.002 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KXX74090.1 - 0.017 14.6 2.7 0.056 12.8 0.2 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KXX74090.1 - 0.1 12.9 3.6 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KXX74090.1 - 0.16 11.5 0.7 0.43 10.1 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KXX74090.1 - 0.25 11.6 0.8 0.66 10.2 0.2 2.0 2 0 0 2 2 2 0 ABC transporter Carb_kinase PF01256.12 KXX74092.1 - 3.6e-54 183.6 0.1 4.9e-54 183.1 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 KXX74092.1 - 0.00097 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 KXX74092.1 - 0.0015 17.7 0.0 0.0031 16.7 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.20 KXX74093.1 - 5.3e-70 235.2 0.0 9.3e-70 234.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KXX74093.1 - 1.2e-26 93.4 0.1 3.6e-26 91.8 0.1 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KXX74093.1 - 1.2e-15 57.4 2.8 3.3e-15 56.0 2.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KXX74093.1 - 0.0052 16.6 1.0 0.013 15.3 0.5 1.9 2 0 0 2 2 2 1 HAS barrel domain YbjQ_1 PF01906.12 KXX74096.1 - 1.1e-27 96.5 0.1 1.3e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.16 KXX74098.1 - 4.7e-106 354.3 0.0 6.4e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KXX74098.1 - 2.8e-54 183.5 2.0 4.9e-54 182.7 1.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX74098.1 - 4.3e-09 36.2 0.1 1.1e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KXX74098.1 - 4.7e-06 26.2 1.0 5.3e-05 22.7 0.2 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KXX74098.1 - 1.4e-05 25.0 0.1 0.0012 18.8 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KXX74098.1 - 0.012 13.9 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.13 KXX74098.1 - 0.031 13.5 0.1 0.31 10.2 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.11 KXX74100.1 - 1e-32 113.2 72.4 7.6e-31 107.0 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74100.1 - 7.5e-14 51.1 5.6 7.5e-14 51.1 3.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 KXX74100.1 - 6.1e-08 31.5 8.4 6.1e-08 31.5 5.8 3.0 2 2 0 2 2 2 1 Vacuole effluxer Atg22 like TRI12 PF06609.8 KXX74100.1 - 4.6e-06 25.1 3.1 0.00088 17.5 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3366 PF11846.3 KXX74100.1 - 0.97 9.2 4.8 18 5.1 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Tetraspannin PF00335.15 KXX74100.1 - 9.2 5.4 11.9 1.1 8.5 1.6 2.5 2 0 0 2 2 2 0 Tetraspanin family CDC45 PF02724.9 KXX74101.1 - 0.81 7.6 2.5 1.1 7.2 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TT_ORF1 PF02956.9 KXX74102.1 - 0.64 8.4 2.5 0.91 7.8 1.7 1.1 1 0 0 1 1 1 0 TT viral orf 1 Pol_alpha_B_N PF08418.5 KXX74102.1 - 0.68 9.4 11.2 0.014 14.9 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal RILP PF11461.3 KXX74102.1 - 3.8 7.7 6.5 0.39 10.9 0.8 2.0 2 0 0 2 2 2 0 Rab interacting lysosomal protein PRA1 PF03208.14 KXX74103.1 - 4.6e-37 126.7 0.4 5.6e-37 126.4 0.2 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF4282 PF14110.1 KXX74103.1 - 0.044 13.9 0.3 0.044 13.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Aldo_ket_red PF00248.16 KXX74105.1 - 3.1e-50 170.5 0.0 3.6e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.15 KXX74105.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS p450 PF00067.17 KXX74106.1 - 3.8e-74 249.8 0.0 4.6e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 KXX74108.1 - 6.1e-23 81.5 4.1 1.3e-19 70.7 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RibD_C PF01872.12 KXX74109.1 - 2.6e-09 37.0 0.0 2.9e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.14 KXX74109.1 - 1.3e-07 31.3 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase RTA1 PF04479.8 KXX74110.1 - 1.4e-36 126.1 2.6 1.9e-36 125.6 1.8 1.1 1 0 0 1 1 1 1 RTA1 like protein UNC-50 PF05216.8 KXX74110.1 - 0.042 13.0 0.0 0.089 11.9 0.0 1.5 1 0 0 1 1 1 0 UNC-50 family DUF3007 PF11460.3 KXX74110.1 - 0.22 11.6 1.2 0.7 10.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Fungal_trans_2 PF11951.3 KXX74111.1 - 0.00055 18.6 0.0 0.00078 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KXX74113.1 - 5e-06 26.4 12.7 0.00069 19.7 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX74113.1 - 6.6e-06 26.1 4.0 6.6e-06 26.1 2.8 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KXX74113.1 - 2.5e-05 24.3 11.7 0.0078 16.5 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Nucleo_P87 PF07267.6 KXX74113.1 - 0.47 9.0 3.0 1.4 7.5 2.2 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2_6 PF13912.1 KXX74113.1 - 3.4 7.6 5.8 0.36 10.7 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Colipase PF01114.13 KXX74114.1 - 0.007 15.8 3.6 0.012 15.1 2.5 1.3 1 0 0 1 1 1 1 Colipase, N-terminal domain PepSY_2 PF13670.1 KXX74114.1 - 1.1 9.1 4.0 6.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain MoaC PF01967.16 KXX74115.1 - 1.5e-42 144.4 0.0 2.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KXX74115.1 - 2.6e-32 111.2 0.0 5.8e-32 110.0 0.0 1.6 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KXX74115.1 - 2.1e-23 83.2 0.0 3.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KXX74115.1 - 6.6e-05 23.0 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KXX74115.1 - 0.0035 17.3 0.4 0.014 15.4 0.1 2.0 2 1 0 2 2 2 1 4Fe-4S single cluster domain dCMP_cyt_deam_1 PF00383.17 KXX74116.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FolB PF02152.13 KXX74117.1 - 1.1e-32 112.4 0.0 4.4e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 Dihydroneopterin aldolase Fig1 PF12351.3 KXX74118.1 - 4.8e-23 81.9 1.9 5.4e-23 81.8 0.0 1.7 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KXX74118.1 - 4.7e-06 26.3 3.8 6.7e-06 25.8 2.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family SLAC1 PF03595.12 KXX74118.1 - 0.0017 17.0 2.1 0.0031 16.2 1.4 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel FolB PF02152.13 KXX74119.1 - 8.2e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Dihydroneopterin aldolase Epimerase PF01370.16 KXX74120.1 - 1.8e-10 40.6 0.0 8e-10 38.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX74120.1 - 1.4e-06 28.4 0.0 6.9e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX74120.1 - 1.2e-05 24.1 0.0 0.00029 19.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX74120.1 - 0.0011 17.9 1.8 0.002 17.1 0.5 2.1 2 1 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 KXX74120.1 - 0.017 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase B12-binding PF02310.14 KXX74120.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain NmrA PF05368.8 KXX74120.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family MGC-24 PF05283.6 KXX74121.1 - 0.037 13.8 12.1 0.048 13.4 8.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF566 PF04484.7 KXX74121.1 - 6 6.2 7.5 7.7 5.9 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PBP PF01161.15 KXX74122.1 - 2.6e-10 40.2 0.1 3e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cation_efflux PF01545.16 KXX74123.1 - 2e-11 43.5 7.4 2.4e-11 43.2 5.2 1.0 1 0 0 1 1 1 1 Cation efflux family Gly_transf_sug PF04488.10 KXX74124.1 - 1.4e-10 41.4 0.0 3.5e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KXX74124.1 - 0.00055 18.5 0.0 0.00096 17.7 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain CorA PF01544.13 KXX74125.1 - 2.7e-14 52.9 2.8 1.9e-12 46.8 1.9 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.21 KXX74126.1 - 9.6e-06 25.6 0.8 9.6e-06 25.6 0.6 2.8 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX74126.1 - 5.3e-05 23.2 7.9 0.00025 21.1 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KXX74126.1 - 0.01 15.9 8.9 0.11 12.6 1.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KXX74126.1 - 0.011 15.6 0.8 0.011 15.6 0.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KXX74126.1 - 0.011 15.8 0.9 0.011 15.8 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type YscJ_FliF_C PF08345.6 KXX74126.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal zf-DBF PF07535.7 KXX74126.1 - 0.69 9.6 5.1 3.4 7.4 0.6 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-HYPF PF07503.7 KXX74126.1 - 2.8 7.4 7.8 3.2 7.2 1.0 2.4 2 0 0 2 2 2 0 HypF finger zf-BED PF02892.10 KXX74126.1 - 2.9 7.7 11.3 0.17 11.6 1.3 2.4 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 KXX74126.1 - 4.6 7.7 12.7 0.21 11.9 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX74126.1 - 5.6 7.2 11.9 1.8 8.8 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Amnionless PF14828.1 KXX74127.1 - 0.16 10.4 0.0 0.28 9.6 0.0 1.4 1 0 0 1 1 1 0 Amnionless Gram_pos_anchor PF00746.16 KXX74127.1 - 9.7 6.1 11.0 1.9 8.3 2.7 2.5 2 0 0 2 2 2 0 Gram positive anchor Glyco_hydro_49 PF03718.8 KXX74128.1 - 0.084 10.9 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 FAP PF07174.6 KXX74128.1 - 0.088 12.0 5.7 0.12 11.6 4.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribosomal_L23 PF00276.15 KXX74129.1 - 4.9e-14 52.0 0.0 8.7e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DUF4066 PF13278.1 KXX74130.1 - 4.3e-24 84.6 1.0 6.9e-23 80.7 0.7 2.0 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX74130.1 - 1.1e-05 24.9 0.0 3.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Hamartin PF04388.7 KXX74131.1 - 7.9e-31 107.4 17.6 2.8e-29 102.3 10.9 3.4 1 1 0 1 1 1 1 Hamartin protein LURAP PF14854.1 KXX74131.1 - 0.39 10.4 5.1 0.25 11.0 1.3 2.5 2 0 0 2 2 2 0 Leucine rich adaptor protein TPR_MLP1_2 PF07926.7 KXX74131.1 - 3 7.6 31.7 1.2 8.8 0.0 3.8 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein Mito_carr PF00153.22 KXX74133.1 - 3.5e-61 202.9 0.2 1.7e-21 75.7 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.9 KXX74134.1 - 8.1e-28 97.1 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 MT-A70 CDC73 PF05179.9 KXX74135.1 - 6.3e-42 143.8 0.0 1.2e-41 142.8 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 KXX74136.1 - 2e-37 127.8 0.9 1.3e-36 125.2 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KXX74136.1 - 1.8e-25 88.4 0.2 4.2e-21 74.4 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.1 KXX74138.1 - 3.4e-60 202.9 0.0 5e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KXX74138.1 - 3.1e-16 59.9 0.3 4.4e-15 56.1 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.1 KXX74138.1 - 2.6e-13 49.0 2.7 4.5e-13 48.2 1.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 KXX74138.1 - 1.6e-10 40.5 6.4 2.8e-10 39.7 4.4 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 KXX74138.1 - 9.5e-09 35.5 0.1 2.7e-08 34.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KXX74138.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX74138.1 - 8e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KXX74138.1 - 0.00011 22.0 0.1 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 KXX74138.1 - 0.00042 19.3 0.0 0.00069 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 KXX74138.1 - 0.00099 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 KXX74138.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 KXX74138.1 - 0.0029 17.1 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KXX74138.1 - 0.0032 18.2 0.0 0.015 16.1 0.0 2.1 1 1 1 2 2 1 1 AAA domain AAA_10 PF12846.2 KXX74138.1 - 0.004 16.6 0.1 0.42 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain KAP_NTPase PF07693.9 KXX74138.1 - 0.0043 16.0 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain MobB PF03205.9 KXX74138.1 - 0.0047 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B C1_1 PF00130.17 KXX74138.1 - 0.0054 16.4 0.5 0.011 15.3 0.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 KXX74138.1 - 0.013 15.4 1.3 0.026 14.4 0.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger PduV-EutP PF10662.4 KXX74138.1 - 0.014 14.8 0.0 0.061 12.8 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KXX74138.1 - 0.014 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KXX74138.1 - 0.017 15.4 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KXX74138.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 KXX74138.1 - 0.045 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 KXX74138.1 - 0.045 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Prok-RING_1 PF14446.1 KXX74138.1 - 0.057 13.1 2.4 0.14 11.9 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 T2SE PF00437.15 KXX74138.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.13 KXX74138.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 KXX74138.1 - 0.093 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-PHD-like PF15446.1 KXX74138.1 - 0.11 11.8 1.9 0.22 10.8 1.3 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Bac_DnaA PF00308.13 KXX74138.1 - 0.13 11.8 0.1 2.4 7.7 0.0 2.5 3 0 0 3 3 3 0 Bacterial dnaA protein cobW PF02492.14 KXX74138.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KXX74138.1 - 0.31 10.5 0.9 0.82 9.1 0.1 2.2 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase zf-RING_2 PF13639.1 KXX74138.1 - 2.4 8.0 6.1 5.9 6.8 4.3 1.7 1 1 0 1 1 1 0 Ring finger domain HGTP_anticodon2 PF12745.2 KXX74139.1 - 0.058 12.5 0.2 0.093 11.8 0.2 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FAD_binding_3 PF01494.14 KXX74141.1 - 5e-38 131.0 0.0 1.7e-19 70.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX74141.1 - 0.00015 20.8 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX74141.1 - 0.00095 19.1 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX74141.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KXX74141.1 - 0.0086 14.5 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KXX74141.1 - 0.034 13.0 0.0 0.051 12.4 0.0 1.3 1 1 0 1 1 1 0 Lycopene cyclase protein GIT_SHD PF08518.6 KXX74141.1 - 0.043 13.1 0.6 0.1 11.9 0.4 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Glyco_hydro_2 PF00703.16 KXX74145.1 - 3.1e-11 43.6 0.8 3.8e-10 40.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KXX74145.1 - 5.5e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Caleosin PF05042.8 KXX74146.1 - 2.6e-53 180.1 0.1 3.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 KXX74146.1 - 1.7e-05 24.2 1.3 0.16 11.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KXX74146.1 - 0.00041 19.4 0.7 4.9 6.6 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 KXX74146.1 - 0.0011 18.1 4.0 1.1 8.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KXX74146.1 - 0.0035 17.4 0.1 6 7.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair Amidohydro_1 PF01979.15 KXX74147.1 - 9.7e-15 55.0 0.1 3.3e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KXX74147.1 - 3.9e-11 42.6 0.8 2.3e-10 40.1 0.5 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX74147.1 - 0.00044 19.5 0.5 0.0097 15.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_43 PF04616.9 KXX74148.1 - 3e-10 39.6 0.3 3.6e-07 29.5 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KXX74148.1 - 5.3e-05 22.7 0.0 0.00061 19.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain ADH_zinc_N PF00107.21 KXX74149.1 - 1e-29 102.7 0.3 1.6e-29 102.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX74149.1 - 6.8e-16 59.3 0.0 2.3e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX74149.1 - 2e-13 50.0 0.1 6e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KXX74149.1 - 0.00095 18.7 0.7 0.0031 17.1 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KXX74149.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KXX74149.1 - 0.058 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RTBV_P12 PF06361.6 KXX74149.1 - 0.06 13.5 0.5 24 5.1 0.0 3.0 3 0 0 3 3 3 0 Rice tungro bacilliform virus P12 protein CTD_bind PF04818.8 KXX74150.1 - 1.8e-10 40.8 0.1 3.2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. B56 PF01603.15 KXX74151.1 - 1.7e-08 33.5 0.3 2e-08 33.2 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3720 PF12517.3 KXX74151.1 - 0.14 12.8 2.3 0.19 12.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) B56 PF01603.15 KXX74152.1 - 7.6e-158 525.4 4.7 9e-158 525.1 3.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 KXX74152.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DUF4243 PF14027.1 KXX74153.1 - 2.5e-90 303.2 2.5 2.9e-90 303.0 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3290 PF11694.3 KXX74153.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) ChaB PF06150.7 KXX74153.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.6 3 0 0 3 3 3 0 ChaB Exo_endo_phos PF03372.18 KXX74154.1 - 2.8e-27 96.2 0.2 5e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BCDHK_Adom3 PF10436.4 KXX74155.1 - 8.4e-45 152.2 1.2 9.8e-45 152.0 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KXX74155.1 - 7.8e-10 38.4 0.2 5e-07 29.4 0.1 2.6 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KXX74155.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 KXX74156.1 - 3.4e-86 288.5 0.0 4.9e-84 281.4 0.0 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KXX74156.1 - 5e-76 254.8 2.9 1.2e-71 240.5 0.2 3.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KXX74156.1 - 1e-55 188.7 2.5 2.2e-55 187.6 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX74156.1 - 2.1e-29 102.9 0.1 3.4e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KXX74156.1 - 3.2e-14 53.1 0.1 3.9e-13 49.6 0.1 2.7 2 0 0 2 2 2 1 MATH domain WD40 PF00400.27 KXX74157.1 - 2e-54 179.6 26.1 3.4e-12 45.7 0.0 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 KXX74157.1 - 1.1e-26 92.9 0.0 1.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KXX74157.1 - 1.5e-07 31.3 0.9 0.023 14.4 0.0 6.0 3 2 3 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KXX74157.1 - 1.4e-05 23.5 0.9 0.21 9.6 0.0 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX74157.1 - 0.00032 19.5 2.7 9.3 4.8 0.0 4.9 1 1 2 4 4 4 2 Nup133 N terminal like IKI3 PF04762.7 KXX74157.1 - 0.00048 18.1 0.0 0.033 12.0 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 KXX74157.1 - 0.0041 16.2 0.2 7.9 5.4 0.0 4.0 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KXX74158.1 - 6.3e-117 389.5 0.4 9.1e-117 389.0 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KXX74158.1 - 5.9e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX74158.1 - 2.5e-06 27.0 0.4 5.7e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KXX74158.1 - 1.1e-05 24.7 0.0 2.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KXX74158.1 - 0.0024 18.3 0.1 0.0081 16.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KXX74158.1 - 0.0033 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX74158.1 - 0.0039 17.3 0.4 0.015 15.3 0.0 2.1 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KXX74158.1 - 0.0054 16.2 0.1 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 KXX74158.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KXX74158.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 KXX74158.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KXX74158.1 - 0.017 14.4 0.6 0.054 12.8 0.4 1.9 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 KXX74158.1 - 0.034 13.0 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 KXX74158.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KXX74158.1 - 0.046 14.0 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 KXX74158.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 KXX74158.1 - 0.071 13.0 3.0 0.36 10.8 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 KXX74158.1 - 0.078 11.7 2.2 0.91 8.2 0.0 2.9 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 KXX74158.1 - 0.08 12.7 7.3 0.7 9.6 0.1 3.1 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 KXX74158.1 - 0.087 12.3 0.8 2.8 7.4 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KXX74158.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 KXX74158.1 - 0.14 12.4 4.8 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e KAP_NTPase PF07693.9 KXX74158.1 - 0.18 10.7 2.6 0.33 9.8 1.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KXX74158.1 - 0.29 10.6 1.1 9.4 5.6 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Val_tRNA-synt_C PF10458.4 KXX74158.1 - 0.69 10.0 6.6 0.16 12.0 0.9 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Atg14 PF10186.4 KXX74158.1 - 0.69 8.7 7.2 1.7 7.5 5.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 KXX74158.1 - 8.3 6.1 13.6 4.5 6.9 4.5 3.1 2 1 0 2 2 2 0 Myc leucine zipper domain Tim17 PF02466.14 KXX74159.1 - 4.3e-48 162.5 12.9 5.6e-48 162.2 9.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KXX74159.1 - 0.045 13.7 0.4 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) HemY_N PF07219.8 KXX74161.1 - 0.00098 18.6 0.3 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 HemY protein N-terminus Sigma_reg_N PF13800.1 KXX74161.1 - 2.8 8.0 4.0 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal IncA PF04156.9 KXX74161.1 - 3.5 7.1 7.0 5.3 6.6 0.0 2.6 3 0 0 3 3 3 0 IncA protein AAA_22 PF13401.1 KXX74163.1 - 2.1e-10 40.8 0.0 5.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KXX74163.1 - 2.5e-08 33.1 0.0 0.00021 20.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_10 PF13374.1 KXX74163.1 - 7.8e-07 28.8 2.8 0.0047 16.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX74163.1 - 4.3e-06 26.5 0.1 2.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_25 PF13481.1 KXX74163.1 - 0.024 14.0 0.0 0.089 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KXX74163.1 - 0.04 13.0 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KXX74163.1 - 0.046 13.6 0.0 0.23 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain TTSSLRR PF12468.3 KXX74163.1 - 1.6 8.3 5.1 0.47 10.0 1.2 1.8 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Raptor_N PF14538.1 KXX74164.1 - 0.012 15.5 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 KXX74164.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF3290 PF11694.3 KXX74165.1 - 0.47 10.1 2.1 1 9.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) NPP1 PF05630.6 KXX74167.1 - 3.2e-75 252.3 0.7 3.7e-75 252.1 0.5 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF1996 PF09362.5 KXX74169.1 - 1.2e-88 296.7 0.2 1.5e-88 296.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DNase_NucA_NucB PF14040.1 KXX74170.1 - 1.4e-07 31.6 0.1 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Fasciclin PF02469.17 KXX74172.1 - 6.2e-19 68.2 0.0 1.4e-15 57.4 0.0 3.0 3 0 0 3 3 3 3 Fasciclin domain Gln-synt_C PF00120.19 KXX74174.1 - 5.3e-51 173.2 0.0 9.3e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KXX74174.1 - 2.7e-27 96.0 0.1 6.4e-27 94.8 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase MR_MLE_C PF13378.1 KXX74174.1 - 0.043 13.7 0.6 0.13 12.2 0.4 1.8 1 0 0 1 1 1 0 Enolase C-terminal domain-like DUF1117 PF06547.7 KXX74175.1 - 0.11 12.6 0.6 0.62 10.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) Semialdhyde_dhC PF02774.13 KXX74175.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Pneumo_att_G PF05539.6 KXX74175.1 - 3.6 6.8 7.3 4.8 6.4 5.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G COPIIcoated_ERV PF07970.7 KXX74176.1 - 3.1e-34 118.5 0.1 5e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KXX74176.1 - 8.1e-19 67.4 0.0 1.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AhpC-TSA_2 PF13911.1 KXX74177.1 - 1.4e-18 66.8 0.0 3.8e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KXX74177.1 - 0.017 14.7 0.0 0.049 13.3 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family Gag_spuma PF03276.9 KXX74177.1 - 0.12 10.6 0.0 0.12 10.6 0.0 1.6 2 0 0 2 2 2 0 Spumavirus gag protein WD40 PF00400.27 KXX74178.1 - 2e-26 90.8 0.8 3.2e-05 23.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KXX74179.1 - 5.5e-17 62.2 0.0 2.6e-14 53.5 0.0 3.5 3 1 0 3 3 3 2 Cytidylyltransferase Aminotran_4 PF01063.14 KXX74181.1 - 2.2e-24 86.2 0.0 3.1e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV UPF1_Zn_bind PF09416.5 KXX74183.1 - 9.5e-72 239.5 5.5 2.5e-71 238.2 1.5 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KXX74183.1 - 4.8e-62 208.9 0.0 1.3e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KXX74183.1 - 5.7e-57 193.0 2.8 9.1e-57 192.3 1.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX74183.1 - 4.9e-14 51.8 0.2 1.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KXX74183.1 - 3.4e-12 46.3 0.4 6.5e-11 42.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KXX74183.1 - 2.9e-07 30.5 0.0 5.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KXX74183.1 - 1.8e-05 24.4 0.1 4.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KXX74183.1 - 3.1e-05 23.6 0.4 0.29 10.6 0.0 3.2 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KXX74183.1 - 0.00024 20.5 0.1 0.0059 15.9 0.1 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KXX74183.1 - 0.00024 20.1 0.2 0.18 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.4 KXX74183.1 - 0.00025 20.1 1.2 0.0015 17.5 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KXX74183.1 - 0.0014 18.1 0.2 0.003 17.0 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 KXX74183.1 - 0.0046 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 KXX74183.1 - 0.0074 15.4 0.0 0.028 13.5 0.0 1.9 3 0 0 3 3 2 1 KaiC Ribosomal_S13_N PF08069.7 KXX74183.1 - 0.0089 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 KXX74183.1 - 0.014 15.4 0.1 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KXX74183.1 - 0.037 13.5 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KXX74183.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 KXX74183.1 - 0.097 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KXX74183.1 - 0.1 12.7 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KXX74183.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KXX74183.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 KXX74183.1 - 0.13 11.6 0.6 0.35 10.2 0.4 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 KXX74183.1 - 0.21 10.8 0.0 0.51 9.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF3435 PF11917.3 KXX74184.1 - 4.5e-68 229.9 0.2 5.9e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CDC45 PF02724.9 KXX74184.1 - 0.061 11.3 4.9 0.11 10.4 3.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.12 KXX74186.1 - 3e-08 33.6 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 KXX74186.1 - 0.025 14.3 0.1 0.087 12.6 0.0 2.0 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Paf67 PF10255.4 KXX74188.1 - 7.3e-151 502.6 0.2 8.5e-151 502.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KXX74188.1 - 0.012 15.4 0.2 0.11 12.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.5 KXX74188.1 - 0.025 14.7 3.3 0.053 13.6 2.3 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Usp PF00582.21 KXX74189.1 - 3.5e-13 49.9 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family RRM_6 PF14259.1 KXX74190.1 - 1.5e-11 44.1 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX74190.1 - 4.6e-10 38.9 0.0 8.9e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX74190.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G0-G1_switch_2 PF15103.1 KXX74190.1 - 0.075 13.2 1.8 0.17 12.1 1.3 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Asp-B-Hydro_N PF05279.6 KXX74190.1 - 0.23 11.2 10.7 0.36 10.6 7.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 KXX74190.1 - 1.1 6.9 1.6 1.3 6.6 1.1 1.0 1 0 0 1 1 1 0 Ycf1 GTP_EFTU PF00009.22 KXX74191.1 - 1.9e-51 174.1 0.0 3.4e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KXX74191.1 - 6.5e-16 57.9 0.0 1.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX74191.1 - 3.9e-10 39.7 0.0 9.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KXX74191.1 - 4.4e-09 35.9 0.0 2.3e-06 27.1 0.0 3.3 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.1 KXX74191.1 - 1.7e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX74191.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAD_binding_4 PF01565.18 KXX74193.1 - 6.7e-16 58.0 1.5 1.3e-15 57.0 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX74193.1 - 2.2e-10 40.2 0.6 4.1e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX74193.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3384 PF11864.3 KXX74195.1 - 0.051 12.0 0.0 0.051 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) gag-asp_proteas PF13975.1 KXX74196.1 - 0.0003 20.5 0.1 0.00078 19.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TMEM171 PF15471.1 KXX74196.1 - 0.16 10.7 1.1 0.33 9.7 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 PepSY_TM_3 PF13706.1 KXX74197.1 - 2.8 7.4 10.1 0.49 9.8 3.7 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix SUR7 PF06687.7 KXX74198.1 - 0.0016 18.0 1.4 0.0018 17.8 1.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family EphA2_TM PF14575.1 KXX74200.1 - 3.6 8.0 0.0 3.6 8.0 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Sulfotransfer_3 PF13469.1 KXX74201.1 - 0.0075 17.2 7.6 0.014 16.3 5.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family adh_short PF00106.20 KXX74202.1 - 1.7e-11 44.3 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KXX74202.1 - 5.6e-05 22.6 0.1 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.4 KXX74202.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain KR PF08659.5 KXX74202.1 - 0.026 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.1 KXX74202.1 - 0.033 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX74202.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding GMC_oxred_N PF00732.14 KXX74203.1 - 2.7e-45 154.7 0.0 3.9e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX74203.1 - 1.6e-35 122.5 0.0 2.5e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HET PF06985.6 KXX74204.1 - 1.3e-27 96.6 0.0 3.3e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HD_3 PF13023.1 KXX74206.1 - 1.7e-47 161.2 0.1 2.1e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 KXX74206.1 - 0.0094 15.9 0.1 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 HD domain HD_2 PF12917.2 KXX74206.1 - 0.079 12.7 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme HET PF06985.6 KXX74207.1 - 8.7e-12 45.3 1.1 6.1e-11 42.6 0.8 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cerato-platanin PF07249.7 KXX74208.1 - 0.062 13.2 0.2 0.088 12.8 0.1 1.2 1 0 0 1 1 1 0 Cerato-platanin FAA_hydrolase PF01557.13 KXX74209.1 - 3.5e-64 216.2 0.0 4.2e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 KXX74209.1 - 0.0021 18.4 0.1 0.0065 16.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2437) Collar PF07484.7 KXX74209.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Collar Domain DUF3433 PF11915.3 KXX74211.1 - 6.4e-36 122.4 21.7 2.4e-21 75.6 0.6 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Alpha-L-AF_C PF06964.7 KXX74213.1 - 3.4e-27 95.3 0.0 5.2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyoxalase PF00903.20 KXX74214.1 - 2.2e-08 34.1 7.9 1.1e-07 31.8 1.9 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX74214.1 - 5.9e-08 33.2 1.8 0.0035 17.9 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KXX74214.1 - 0.00041 20.3 0.5 0.025 14.6 0.1 2.6 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 KXX74215.1 - 1.3e-79 267.8 0.0 1.9e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KXX74215.1 - 5.6e-72 242.7 0.0 7.8e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 KXX74215.1 - 0.00099 18.1 0.1 0.014 14.2 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX74215.1 - 0.0013 18.6 0.5 0.0034 17.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX74215.1 - 0.018 14.1 0.1 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KXX74215.1 - 0.026 13.4 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX74215.1 - 0.026 14.5 1.5 0.062 13.3 1.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX74215.1 - 0.027 13.3 0.8 0.047 12.5 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KXX74215.1 - 0.12 12.3 0.3 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX74215.1 - 0.53 9.0 1.7 0.8 8.4 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PilM PF07419.7 KXX74217.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 PilM PNP_UDP_1 PF01048.15 KXX74218.1 - 4e-06 25.9 0.1 1.7e-05 23.8 0.0 1.9 1 1 1 2 2 2 2 Phosphorylase superfamily FA_desaturase PF00487.19 KXX74219.1 - 4.1 6.7 9.8 5.3 6.4 6.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Ank_2 PF12796.2 KXX74220.1 - 8.5e-64 211.9 0.7 7.2e-22 77.5 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74220.1 - 1.2e-48 160.5 1.5 3.9e-08 32.7 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 KXX74220.1 - 2.3e-33 110.8 1.5 4.5e-05 23.2 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KXX74220.1 - 8e-32 109.0 0.9 6.5e-08 32.8 0.0 5.7 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX74220.1 - 9.2e-29 98.8 0.9 1.1e-05 25.4 0.0 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 KXX74220.1 - 0.007 16.6 0.3 0.007 16.6 0.2 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger Methyltransf_29 PF03141.11 KXX74220.1 - 0.022 13.1 0.1 4 5.6 0.0 2.8 2 1 1 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase zf-C2H2 PF00096.21 KXX74220.1 - 0.04 14.2 0.2 0.04 14.2 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF629 PF04780.7 KXX74220.1 - 2.9 6.3 4.9 0.73 8.2 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Ank_2 PF12796.2 KXX74221.1 - 1.4e-15 57.3 0.5 4.5e-11 42.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74221.1 - 2.9e-13 48.9 1.3 0.00012 21.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX74221.1 - 2.6e-12 46.5 0.1 1.6e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX74221.1 - 3.7e-10 40.0 0.2 0.003 18.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74221.1 - 8.3e-08 31.7 0.1 0.023 14.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat vWA-TerF-like PF10138.4 KXX74221.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF3584 PF12128.3 KXX74223.1 - 0.046 11.0 41.9 0.064 10.5 29.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.7 KXX74223.1 - 0.05 11.4 41.0 0.072 10.8 28.4 1.2 1 0 0 1 1 1 0 HOOK protein DUF4250 PF14056.1 KXX74223.1 - 2.5 7.8 17.9 0.52 10.0 0.5 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4250) Macoilin PF09726.4 KXX74223.1 - 4.2 5.5 31.8 5.7 5.1 22.1 1.1 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 KXX74223.1 - 6.1 4.5 20.7 8.6 4.0 14.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.1 KXX74223.1 - 7.5 5.9 54.5 0.18 11.1 18.0 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease NACHT PF05729.7 KXX74227.1 - 1.3e-18 67.2 0.0 2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX74227.1 - 0.0052 16.7 0.2 0.023 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX74227.1 - 0.017 15.2 0.1 0.062 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 KXX74227.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.4 KXX74227.1 - 0.055 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KXX74227.1 - 0.056 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.6 KXX74228.1 - 2e-21 76.0 0.0 2.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KXX74228.1 - 8.6e-12 44.8 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KXX74228.1 - 4.5e-06 25.9 0.3 0.00039 19.5 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 KXX74228.1 - 4.2e-05 22.7 0.0 7.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 KXX74228.1 - 0.084 13.0 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb2_6 PF00562.23 KXX74229.1 - 2.6e-95 319.4 0.0 4.6e-95 318.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KXX74229.1 - 3.4e-49 166.5 0.1 8.4e-49 165.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KXX74229.1 - 3.6e-30 104.0 0.8 8.5e-30 102.8 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KXX74229.1 - 3.4e-28 98.3 0.0 1.4e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KXX74229.1 - 2.3e-21 75.2 0.0 4.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KXX74229.1 - 3.4e-19 68.4 0.0 8.6e-19 67.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KXX74229.1 - 8.6e-14 51.2 0.2 2.7e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 KXX74230.1 - 1.6e-61 200.4 11.1 4.7e-08 32.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 KXX74230.1 - 0.024 13.7 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF342 PF03961.8 KXX74230.1 - 0.96 7.7 2.3 1.5 7.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Tnp_P_element PF12017.3 KXX74230.1 - 1.6 7.8 3.2 2.5 7.2 1.4 1.8 2 0 0 2 2 2 0 Transposase protein Ribosomal_L15e PF00827.12 KXX74231.1 - 7.4e-91 302.8 10.5 8.4e-91 302.6 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Carn_acyltransf PF00755.15 KXX74233.1 - 1.5e-168 561.6 0.0 6.4e-152 506.6 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase EphA2_TM PF14575.1 KXX74234.1 - 0.027 14.8 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Bacteriocin_IIc PF10439.4 KXX74234.1 - 2.7 8.1 9.7 4.7 7.3 1.3 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF2205 PF10224.4 KXX74236.1 - 2.8e-33 113.3 1.3 3.1e-33 113.1 0.9 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF4200 PF13863.1 KXX74236.1 - 0.0037 17.1 0.5 0.0045 16.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_32 PF13654.1 KXX74236.1 - 0.026 13.2 0.1 0.027 13.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 KXX74236.1 - 0.041 13.1 0.2 0.044 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AA_permease_2 PF13520.1 KXX74237.1 - 3.4e-60 203.7 33.6 4.2e-60 203.4 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX74237.1 - 1.1e-25 89.9 30.5 3.1e-24 85.1 15.2 2.0 2 0 0 2 2 2 2 Amino acid permease ECH PF00378.15 KXX74238.1 - 3.9e-16 58.9 2.2 8e-11 41.5 1.4 3.7 3 1 1 4 4 4 3 Enoyl-CoA hydratase/isomerase family Sugar_tr PF00083.19 KXX74239.1 - 1.3e-77 261.3 24.1 1.5e-77 261.1 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX74239.1 - 1.4e-27 96.4 25.3 1.4e-27 96.4 17.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX74239.1 - 0.0026 16.2 8.3 0.0026 16.2 5.8 3.0 2 2 0 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 KXX74239.1 - 1.1 9.3 6.5 0.8 9.7 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) HET PF06985.6 KXX74240.1 - 1.3e-23 83.7 0.0 2.6e-23 82.7 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KXX74241.1 - 4.5e-41 139.0 0.0 2.6e-09 37.2 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74241.1 - 2.1e-37 125.0 7.6 1.3e-06 27.9 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KXX74241.1 - 1e-32 111.3 8.3 5.5e-07 29.6 0.0 7.6 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX74241.1 - 2e-31 107.7 0.1 3.2e-07 30.6 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74241.1 - 8e-24 81.3 0.7 0.055 13.7 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.7 KXX74242.1 - 0.0038 16.8 0.1 0.012 15.3 0.1 1.7 1 1 1 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.15 KXX74243.1 - 0.00017 20.6 2.7 0.001 18.1 1.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily FCSD-flav_bind PF09242.6 KXX74245.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Ank_4 PF13637.1 KXX74246.1 - 2e-16 60.0 0.1 6.5e-09 36.0 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX74246.1 - 1.5e-12 47.6 0.0 5.1e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74246.1 - 2.5e-10 39.6 0.0 7.2e-06 25.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KXX74246.1 - 3.4e-09 36.0 0.1 0.00012 22.0 0.0 3.6 4 0 0 4 4 2 2 Ankyrin repeat Ank_5 PF13857.1 KXX74246.1 - 1.8e-08 34.3 0.0 1.4e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) NACHT PF05729.7 KXX74246.1 - 1.4e-07 31.3 0.1 5.4e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX74246.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX74246.1 - 0.0002 21.5 0.0 0.00059 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KXX74246.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KXX74246.1 - 0.033 13.0 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 KXX74246.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain HflK_N PF12221.3 KXX74246.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal ABC_tran PF00005.22 KXX74246.1 - 0.083 13.1 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 KXX74246.1 - 0.12 11.3 0.4 9 5.1 0.1 2.1 1 1 0 2 2 2 0 KAP family P-loop domain cobW PF02492.14 KXX74246.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KXX74246.1 - 0.14 11.6 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 KXX74246.1 - 0.17 10.6 0.0 0.62 8.7 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Glyco_hydro_3 PF00933.16 KXX74247.1 - 1.5e-86 290.0 0.0 2.1e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX74247.1 - 1.5e-38 132.6 0.0 3.5e-37 128.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX74247.1 - 3.7e-23 81.2 0.0 6.3e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CN_hydrolase PF00795.17 KXX74248.1 - 2.6e-32 111.6 0.0 4.3e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_10 PF00331.15 KXX74249.1 - 1.9e-86 289.9 0.0 2.2e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.19 KXX74249.1 - 0.066 12.4 0.3 1 8.6 0.0 2.6 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF3505 PF12013.3 KXX74250.1 - 7.9e-10 38.9 0.1 2.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 KXX74250.1 - 0.0012 18.9 1.7 0.0012 18.9 1.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc-finger domain Uds1 PF15456.1 KXX74251.1 - 2.2e-33 114.8 8.3 6.8e-33 113.2 5.8 1.9 1 0 0 1 1 1 1 Up-regulated During Septation G-alpha PF00503.15 KXX74252.1 - 3.9e-117 391.2 0.1 4.8e-117 390.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KXX74252.1 - 1e-13 50.9 0.6 1.5e-08 34.1 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX74252.1 - 0.00026 20.2 0.5 0.049 12.7 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KXX74252.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KXX74252.1 - 0.046 13.1 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX74252.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spermine_synth PF01564.12 KXX74253.1 - 3e-99 330.9 0.0 4.4e-99 330.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KXX74253.1 - 3.6e-05 23.7 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74253.1 - 0.00017 22.1 0.0 0.00031 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74253.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KXX74253.1 - 0.00081 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 KXX74253.1 - 0.0035 17.7 0.4 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 KXX74253.1 - 0.0064 15.7 0.3 0.066 12.3 0.1 2.2 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KXX74253.1 - 0.033 13.9 0.0 0.09 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KXX74253.1 - 0.05 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Zn_clus PF00172.13 KXX74255.1 - 3.2e-07 30.1 7.4 4.8e-07 29.5 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.10 KXX74256.1 - 0.0003 20.9 1.7 0.0016 18.5 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FAM104 PF15434.1 KXX74256.1 - 0.064 13.4 0.5 0.092 12.9 0.3 1.3 1 0 0 1 1 1 0 Family 104 SR-25 PF10500.4 KXX74256.1 - 0.63 9.4 4.7 0.88 8.9 3.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAD PF02109.11 KXX74257.1 - 1.8e-43 147.1 0.2 2.4e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 DAD family GRASP55_65 PF04495.9 KXX74258.1 - 8.7e-48 161.8 0.0 9.1e-47 158.5 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Fer4_13 PF13370.1 KXX74259.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-HIT PF04438.11 KXX74260.1 - 5.1e-08 32.4 9.9 7.3e-08 31.9 6.9 1.2 1 0 0 1 1 1 1 HIT zinc finger SR-25 PF10500.4 KXX74260.1 - 0.021 14.3 8.5 0.035 13.5 5.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Barwin PF00967.12 KXX74260.1 - 0.11 12.1 3.4 0.23 11.1 2.4 1.4 1 0 0 1 1 1 0 Barwin family Thioredoxin PF00085.15 KXX74262.1 - 6.7e-62 205.6 8.8 9.5e-32 108.7 0.2 3.9 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 KXX74262.1 - 2.8e-52 177.2 4.2 1.8e-37 128.9 0.3 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KXX74262.1 - 6.6e-11 42.4 3.9 0.00064 19.9 0.1 4.7 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KXX74262.1 - 9.7e-11 41.5 0.1 0.00014 21.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KXX74262.1 - 2e-10 40.6 0.1 0.0017 18.4 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KXX74262.1 - 2e-09 37.1 2.4 0.0039 16.8 0.1 3.6 3 0 0 3 3 3 3 AhpC/TSA family Redoxin PF08534.5 KXX74262.1 - 3.5e-09 36.3 6.3 0.00096 18.7 0.0 3.7 4 0 0 4 4 4 3 Redoxin Calsequestrin PF01216.12 KXX74262.1 - 5.1e-06 25.5 1.8 9.9e-06 24.5 1.2 1.5 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.8 KXX74262.1 - 5.4e-05 23.1 4.3 0.26 11.2 0.2 4.5 3 2 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 KXX74262.1 - 0.0042 17.1 5.6 0.59 10.1 0.4 3.7 3 2 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 KXX74262.1 - 0.15 11.9 0.9 0.59 9.9 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain Mon1 PF03164.9 KXX74263.1 - 3.5e-107 358.5 0.0 2.2e-106 355.9 0.0 1.9 1 1 0 1 1 1 1 Trafficking protein Mon1 HpaP PF09483.5 KXX74263.1 - 9.4 6.1 9.4 0.74 9.7 0.1 2.4 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Dopey_N PF04118.9 KXX74264.1 - 1.6e-117 391.7 0.0 4.4e-117 390.2 0.0 1.8 2 0 0 2 2 2 1 Dopey, N-terminal Methyltransf_15 PF09445.5 KXX74265.1 - 2.2e-43 147.6 0.0 3.6e-43 146.9 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 KXX74265.1 - 1.2e-06 29.1 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX74265.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KXX74265.1 - 9.2e-06 25.3 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 KXX74265.1 - 7.2e-05 22.4 0.0 0.00021 20.9 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KXX74265.1 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 KXX74265.1 - 0.0014 17.6 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 KXX74265.1 - 0.0097 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KXX74265.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 KXX74265.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DNA_methylase PF00145.12 KXX74265.1 - 0.18 10.8 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Aminotran_5 PF00266.14 KXX74266.1 - 2.3e-25 89.1 0.0 2.9e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pox_M2 PF04887.7 KXX74266.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein DASH_Dad2 PF08654.5 KXX74267.1 - 8.5e-32 109.2 1.9 1.6e-31 108.3 1.3 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.17 KXX74267.1 - 0.066 13.2 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.1 KXX74267.1 - 0.18 12.2 1.8 0.3 11.5 1.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) p450 PF00067.17 KXX74268.1 - 6e-68 229.4 0.0 6.9e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 L_protein_N PF15518.1 KXX74268.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus CRM1_C PF08767.6 KXX74269.1 - 1.7e-130 434.5 2.3 1.7e-130 434.5 1.6 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KXX74269.1 - 1.1e-41 142.1 6.5 1.1e-41 142.1 4.5 3.3 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KXX74269.1 - 1e-10 41.3 0.0 4.7e-10 39.2 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KXX74269.1 - 0.016 15.6 0.6 1.2 9.6 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region C8 PF08742.6 KXX74269.1 - 0.083 13.1 1.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 C8 domain DUF3385 PF11865.3 KXX74269.1 - 0.17 11.8 0.1 0.17 11.8 0.0 3.5 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) IBR PF01485.16 KXX74270.1 - 4.2e-15 55.3 57.4 3.1e-09 36.5 4.6 4.6 4 1 0 4 4 4 3 IBR domain Strep_SA_rep PF06696.6 KXX74270.1 - 0.0077 15.9 0.3 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Streptococcal surface antigen repeat HA PF03457.9 KXX74271.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 0 Helicase associated domain COesterase PF00135.23 KXX74272.1 - 9.3e-86 288.6 0.0 6.2e-81 272.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX74272.1 - 1.1e-07 31.6 0.7 4.7e-07 29.5 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2798 PF11391.3 KXX74273.1 - 0.033 13.9 3.1 1.1 9.1 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) IMS PF00817.15 KXX74274.1 - 1.6e-32 112.3 0.0 2.7e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX74274.1 - 0.00027 20.8 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KXX74274.1 - 0.0083 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif UPF0547 PF10571.4 KXX74274.1 - 0.047 13.3 0.8 0.84 9.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 HLH PF00010.21 KXX74275.1 - 1.4e-06 27.9 0.0 3.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC27 PF09507.5 KXX74275.1 - 0.74 8.9 13.6 1.2 8.2 9.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Shugoshin_N PF07558.6 KXX74276.1 - 7.6e-15 54.3 3.9 1.6e-14 53.3 2.7 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KXX74276.1 - 4.2e-12 45.2 5.7 4.2e-12 45.2 4.0 3.4 3 0 0 3 3 3 1 Shugoshin C terminus AKNA PF12443.3 KXX74276.1 - 0.0021 18.0 0.8 0.0072 16.3 0.6 1.9 1 0 0 1 1 1 1 AT-hook-containing transcription factor HALZ PF02183.13 KXX74276.1 - 0.13 12.0 1.4 0.32 10.7 1.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper TerB-C PF15615.1 KXX74276.1 - 2.9 8.1 7.4 0.74 10.0 1.6 2.7 2 0 0 2 2 2 0 TerB-C domain Metallophos_2 PF12850.2 KXX74278.1 - 2.8e-14 53.2 0.0 3.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX74278.1 - 0.0012 18.2 0.0 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RPEL PF02755.10 KXX74279.1 - 4.4e-19 67.1 3.0 3.3e-10 38.9 0.1 2.5 3 0 0 3 3 3 2 RPEL repeat GMC_oxred_N PF00732.14 KXX74280.1 - 1.8e-50 171.7 0.0 2.9e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX74280.1 - 3.4e-31 108.4 0.1 5.5e-31 107.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX74280.1 - 0.062 12.1 0.1 0.55 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX74280.1 - 0.063 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.23 KXX74281.1 - 7.3e-46 157.1 0.0 8.5e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NR_Repeat PF14046.1 KXX74282.1 - 0.41 10.4 4.7 1.4 8.6 3.3 1.9 1 0 0 1 1 1 0 Nuclear receptor repeat PALP PF00291.20 KXX74283.1 - 4e-76 256.1 0.7 4.9e-76 255.8 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KXX74283.1 - 3.1e-39 132.4 0.0 9.8e-21 73.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase FKBP_C PF00254.23 KXX74284.1 - 2.5e-31 107.5 0.0 3.5e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Tannase PF07519.6 KXX74285.1 - 3e-97 326.2 0.2 8.9e-97 324.7 0.2 1.6 1 1 0 1 1 1 1 Tannase and feruloyl esterase IMS PF00817.15 KXX74286.1 - 1.5e-42 144.8 0.0 3.4e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX74286.1 - 1.4e-14 54.1 0.1 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KXX74286.1 - 1.4e-05 24.8 0.0 4.6e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif Syntaxin PF00804.20 KXX74287.1 - 2.6e-07 30.7 6.0 2.6e-07 30.7 4.1 2.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.14 KXX74287.1 - 1.9e-06 27.4 9.5 1.9e-06 27.4 6.6 2.8 3 0 0 3 3 3 1 SNARE domain DUF1183 PF06682.7 KXX74287.1 - 1.1e-05 25.1 0.5 1.1e-05 25.1 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) P12 PF12669.2 KXX74287.1 - 0.00022 21.3 0.3 0.00041 20.5 0.2 1.4 1 0 0 1 1 1 1 Virus attachment protein p12 family Rifin_STEVOR PF02009.11 KXX74287.1 - 0.00026 20.7 4.6 0.00038 20.1 2.8 1.3 1 1 0 1 1 1 1 Rifin/stevor family DUF1510 PF07423.6 KXX74287.1 - 0.01 15.2 0.0 0.01 15.2 0.0 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1510) DUF4094 PF13334.1 KXX74287.1 - 0.032 14.6 0.4 0.032 14.6 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF2370 PF10176.4 KXX74287.1 - 0.088 12.1 0.0 0.088 12.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) SecG PF03840.9 KXX74287.1 - 0.21 11.3 4.1 1.3 8.8 1.5 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Allexi_40kDa PF05549.6 KXX74287.1 - 6.2 6.0 7.2 1 8.6 1.7 1.9 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF912 PF06024.7 KXX74287.1 - 6.3 6.9 14.4 0.096 12.7 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Chordopox_A13L PF05961.6 KXX74287.1 - 6.3 6.8 5.5 20 5.1 3.8 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Chorion_3 PF05387.6 KXX74287.1 - 6.4 6.1 12.8 1.1 8.6 3.0 2.3 2 0 0 2 2 2 0 Chorion family 3 Memo PF01875.12 KXX74288.1 - 2.6e-75 252.8 0.0 3.1e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rhodanese PF00581.15 KXX74289.1 - 6.5e-21 74.8 0.0 9.5e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain TLD PF07534.11 KXX74290.1 - 3.5e-30 104.8 0.0 8.8e-30 103.5 0.0 1.7 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 KXX74290.1 - 8.5e-13 48.3 0.3 2.8e-12 46.6 0.2 2.0 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 KXX74291.1 - 1.8e-21 75.6 0.4 3.8e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SprA-related PF12118.3 KXX74291.1 - 0.022 14.1 14.7 0.038 13.3 2.0 2.2 2 0 0 2 2 2 0 SprA-related family Pilt PF15453.1 KXX74291.1 - 0.046 13.4 6.9 0.05 13.2 4.8 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF445 PF04286.7 KXX74291.1 - 0.046 13.2 2.3 0.055 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1777 PF08648.7 KXX74291.1 - 0.066 12.9 9.8 0.11 12.2 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Potyvirid-P3 PF13608.1 KXX74291.1 - 0.14 11.2 4.1 0.18 10.8 2.8 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Neur_chan_memb PF02932.11 KXX74291.1 - 0.18 11.6 1.5 0.26 11.1 1.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UNC-79 PF14776.1 KXX74291.1 - 0.19 10.0 0.6 0.35 9.1 0.1 1.5 1 1 1 2 2 2 0 Cation-channel complex subunit UNC-79 DUF2637 PF10935.3 KXX74291.1 - 0.59 10.0 3.6 0.15 11.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) RAB3GAP2_N PF14655.1 KXX74291.1 - 3.3 6.6 5.2 1.3 7.9 0.2 2.3 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SHR3_chaperone PF08229.6 KXX74291.1 - 7.4 5.4 7.4 0.24 10.3 0.3 2.0 2 0 0 2 2 2 0 ER membrane protein SH3 DUF1168 PF06658.7 KXX74291.1 - 8.6 5.8 21.9 18 4.8 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) MFS_1 PF07690.11 KXX74293.1 - 1.5e-11 43.6 21.9 1.8e-11 43.4 15.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74293.1 - 1.2e-09 37.3 11.9 1.5e-09 36.9 8.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1749 PF08538.5 KXX74294.1 - 1.2e-82 277.1 0.0 1.4e-82 277.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KXX74294.1 - 4.1e-12 46.4 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX74294.1 - 2e-05 24.3 0.0 8.1e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX74294.1 - 0.0012 18.4 0.0 0.014 14.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX74294.1 - 0.084 12.0 0.0 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3290 PF11694.3 KXX74296.1 - 0.47 10.1 2.1 1 9.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) SnoaL_2 PF12680.2 KXX74299.1 - 1.2e-05 25.6 0.2 1.5e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KXX74299.1 - 0.0023 17.5 0.2 0.011 15.3 0.1 1.8 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase PHZA_PHZB PF03284.8 KXX74299.1 - 0.028 13.5 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B DUF1917 PF08939.5 KXX74301.1 - 0.003 17.3 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Ank_2 PF12796.2 KXX74302.1 - 4.5e-67 222.4 11.1 9.4e-18 64.3 0.1 4.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74302.1 - 1e-37 126.0 4.2 2.4e-08 33.3 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KXX74302.1 - 6.6e-33 112.5 1.1 6e-09 36.1 0.0 7.0 3 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX74302.1 - 6.7e-33 111.9 6.6 1.4e-09 37.9 0.0 6.2 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74302.1 - 3.6e-27 91.7 1.7 5.8e-05 22.9 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat Raptor_N PF14538.1 KXX74303.1 - 0.012 15.5 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 KXX74303.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Caspase domain TPR_10 PF13374.1 KXX74304.1 - 7.9e-07 28.8 2.8 0.0046 16.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX74304.1 - 4.3e-06 26.5 0.1 2.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat NB-ARC PF00931.17 KXX74304.1 - 7.1e-05 21.8 0.0 0.00021 20.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 KXX74304.1 - 0.00017 21.7 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TTSSLRR PF12468.3 KXX74304.1 - 1.6 8.3 5.1 0.46 10.0 1.2 1.8 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein DUF1996 PF09362.5 KXX74306.1 - 3.6e-88 295.2 0.4 4.3e-88 294.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.13 KXX74307.1 - 1.4e-05 24.1 0.0 2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74307.1 - 0.0032 17.3 5.0 0.0056 16.5 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.3 KXX74308.1 - 0.037 13.6 0.1 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Pectate_lyase_3 PF12708.2 KXX74310.1 - 4.2e-30 105.5 3.1 7.9e-20 71.9 0.2 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein DUF3328 PF11807.3 KXX74311.1 - 3.7e-30 105.2 1.4 4.4e-30 104.9 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Mid2 PF04478.7 KXX74312.1 - 0.013 14.9 0.0 0.04 13.3 0.0 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor adh_short PF00106.20 KXX74313.1 - 1.6e-14 54.1 1.8 2.9e-14 53.3 1.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX74313.1 - 1.6e-06 27.9 0.5 2.4e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX74313.1 - 0.018 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Beta-lactamase2 PF13354.1 KXX74313.1 - 0.04 13.3 0.1 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family DSBA PF01323.15 KXX74314.1 - 4.1e-29 101.5 0.0 7.8e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KXX74314.1 - 0.0085 15.8 0.1 1.4 8.8 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin domain TPR_1 PF00515.23 KXX74314.1 - 0.14 11.8 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_clus PF00172.13 KXX74315.1 - 4.7 7.2 19.5 0.079 12.8 8.4 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 KXX74317.1 - 1.2e-85 287.6 0.0 1.7e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX74317.1 - 5.2e-07 28.7 0.2 1.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KXX74317.1 - 2.8e-06 25.9 0.0 4.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KXX74317.1 - 0.029 13.4 0.2 0.081 11.9 0.2 1.7 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.3 KXX74317.1 - 0.046 11.9 0.0 0.07 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Ank_4 PF13637.1 KXX74318.1 - 7.7e-15 54.9 0.1 1.1e-07 32.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX74318.1 - 9.2e-12 45.1 0.1 8.1e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX74318.1 - 1.2e-11 43.6 0.1 0.015 15.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 KXX74318.1 - 2.4e-11 42.8 0.6 0.00027 20.6 0.0 3.4 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX74318.1 - 2.9e-11 43.2 4.3 4.8e-07 29.8 0.5 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) APH PF01636.18 KXX74319.1 - 9.9e-13 48.3 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX74319.1 - 0.00027 20.5 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lyase_1 PF00206.15 KXX74320.1 - 1.8e-21 76.6 0.2 2.9e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KXX74320.1 - 2.4e-15 56.3 0.1 2.1e-14 53.2 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HK PF02110.10 KXX74321.1 - 1.3e-76 257.0 0.3 2e-76 256.4 0.2 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KXX74321.1 - 1.6e-56 190.2 0.3 2.4e-56 189.6 0.2 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KXX74321.1 - 0.00036 19.8 0.1 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KXX74321.1 - 0.0018 17.5 0.0 0.004 16.3 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glyco_hydro_3_C PF01915.17 KXX74321.1 - 0.041 13.4 0.1 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Isochorismatase PF00857.15 KXX74322.1 - 1e-26 93.9 0.1 1.4e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 KXX74323.1 - 1.2e-18 67.9 0.0 1.5e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX74323.1 - 2.1e-17 63.7 0.0 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_30 PF02055.11 KXX74324.1 - 3.4e-18 65.1 0.7 5.8e-17 61.0 0.5 2.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KXX74324.1 - 7.4e-12 44.8 0.0 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 SNF2_N PF00176.18 KXX74325.1 - 6.3e-46 156.5 0.0 1e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX74325.1 - 6.9e-12 45.0 0.1 2.1e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIIS_M PF07500.9 KXX74325.1 - 0.0079 16.2 0.1 0.038 14.0 0.1 2.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain GSH_synth_ATP PF03917.12 KXX74326.1 - 9.9e-50 169.1 0.0 1.3e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain tRNA-synt_1c PF00749.16 KXX74329.1 - 1e-95 320.0 0.0 1.3e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KXX74329.1 - 1.7e-32 112.4 0.0 4.6e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.16 KXX74330.1 - 2.6e-36 124.0 0.0 4.2e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Macro domain CsbD PF05532.7 KXX74331.1 - 6.2e-09 35.3 2.7 0.00016 21.2 0.0 2.2 2 0 0 2 2 2 2 CsbD-like ABC_tran PF00005.22 KXX74332.1 - 4.9e-47 159.6 0.1 4.6e-24 85.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX74332.1 - 1.9e-17 64.1 0.0 0.00073 19.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KXX74332.1 - 7.4e-16 58.0 0.0 1.4e-05 24.4 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX74332.1 - 4.7e-10 38.8 0.1 0.0012 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX74332.1 - 1.1e-09 38.9 1.8 0.00042 20.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KXX74332.1 - 7.8e-08 33.1 0.0 0.0083 16.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX74332.1 - 8.6e-08 31.5 0.0 0.0011 18.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 KXX74332.1 - 1.9e-07 31.2 0.1 0.012 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KXX74332.1 - 2.8e-07 30.2 0.1 0.14 11.6 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 KXX74332.1 - 3.4e-07 30.4 0.0 0.0039 17.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KXX74332.1 - 3.9e-07 30.0 0.0 0.0063 16.4 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KXX74332.1 - 6.2e-07 28.8 0.4 0.21 10.6 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KXX74332.1 - 2.5e-06 27.4 0.0 0.16 11.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.18 KXX74332.1 - 5.1e-06 26.4 0.0 0.00088 19.1 0.0 2.8 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 KXX74332.1 - 6.4e-06 25.1 0.7 0.079 11.7 0.0 2.9 3 0 0 3 3 3 2 ArgK protein AAA_18 PF13238.1 KXX74332.1 - 8.8e-06 26.0 0.2 0.24 11.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KXX74332.1 - 1.3e-05 25.0 0.0 0.024 14.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KXX74332.1 - 1.6e-05 25.3 0.0 0.064 13.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 KXX74332.1 - 1.8e-05 24.9 0.3 0.42 10.8 0.0 4.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KXX74332.1 - 2.5e-05 24.0 0.0 0.29 10.8 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_N PF01602.15 KXX74332.1 - 6e-05 21.5 1.0 0.00011 20.7 0.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region PduV-EutP PF10662.4 KXX74332.1 - 0.00011 21.6 0.0 0.13 11.7 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KXX74332.1 - 0.00013 22.0 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 KXX74332.1 - 0.00015 21.7 1.2 0.81 9.6 0.0 4.3 5 0 0 5 5 5 1 AAA ATPase domain HEAT_2 PF13646.1 KXX74332.1 - 0.00016 21.9 8.4 0.039 14.2 3.5 3.6 1 1 1 3 3 3 2 HEAT repeats NACHT PF05729.7 KXX74332.1 - 0.00023 20.8 0.1 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 KXX74332.1 - 0.00048 20.0 0.0 2.1 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain ParcG PF10274.4 KXX74332.1 - 0.00057 19.8 0.8 4 7.2 0.0 3.2 1 1 2 3 3 3 0 Parkin co-regulated protein AAA_13 PF13166.1 KXX74332.1 - 0.0006 18.4 4.1 1.5 7.2 0.0 4.2 4 1 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 KXX74332.1 - 0.00088 19.0 0.0 1.1 8.8 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 KXX74332.1 - 0.0013 18.1 0.2 1.7 8.0 0.0 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.17 KXX74332.1 - 0.0014 18.5 0.8 4.3 7.6 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat DUF87 PF01935.12 KXX74332.1 - 0.0014 18.4 1.7 0.82 9.4 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KXX74332.1 - 0.0018 17.8 0.3 1.6 8.1 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KXX74332.1 - 0.0026 17.1 0.0 1.9 7.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 KXX74332.1 - 0.0028 17.2 0.3 6.7 6.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX74332.1 - 0.0064 15.9 0.0 5.3 6.4 0.0 3.6 3 1 0 3 3 3 0 FtsK/SpoIIIE family MutS_V PF00488.16 KXX74332.1 - 0.0098 15.3 0.2 0.74 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V Septin PF00735.13 KXX74332.1 - 0.015 14.3 0.5 2 7.3 0.0 2.9 3 0 0 3 3 3 0 Septin ATP_bind_1 PF03029.12 KXX74332.1 - 0.02 14.4 0.7 7.9 5.9 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KXX74332.1 - 0.054 12.8 0.0 14 5.0 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PRK PF00485.13 KXX74332.1 - 0.059 12.9 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 KXX74332.1 - 0.06 12.0 0.0 6.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DAP3 PF10236.4 KXX74332.1 - 0.57 9.0 6.3 5.6 5.7 0.6 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 HEAT_EZ PF13513.1 KXX74332.1 - 5.3 7.6 12.0 15 6.2 0.7 5.2 4 2 3 7 7 3 0 HEAT-like repeat Ank_2 PF12796.2 KXX74333.1 - 4e-59 196.9 9.4 2.4e-12 47.0 0.1 8.4 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74333.1 - 1e-47 157.6 23.7 5.3e-11 41.7 0.0 12.8 13 1 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.1 KXX74333.1 - 3.5e-42 138.1 16.9 1.3e-08 34.2 0.0 13.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 KXX74333.1 - 1e-41 140.5 12.8 1.3e-06 28.7 0.0 9.5 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX74333.1 - 2.7e-31 106.8 15.8 5e-08 32.9 0.0 8.7 9 2 1 10 10 10 6 Ankyrin repeats (many copies) F-box-like PF12937.2 KXX74333.1 - 0.1 12.3 0.7 0.54 10.0 0.3 2.2 2 0 0 2 2 2 0 F-box-like SAS4 PF15460.1 KXX74334.1 - 2.3e-36 123.7 0.3 5e-36 122.6 0.2 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.4 KXX74334.1 - 0.04 14.1 12.1 0.019 15.2 5.3 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CamS PF07537.6 KXX74334.1 - 0.087 11.8 0.1 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 CamS sex pheromone cAM373 precursor BTB PF00651.26 KXX74335.1 - 3.4e-08 33.4 0.0 1.1e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain APC_CDC26 PF10471.4 KXX74338.1 - 7.6e-11 42.6 0.5 7.6e-11 42.6 0.4 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex APC subunit 1 Nucleoplasmin PF03066.10 KXX74338.1 - 0.099 12.1 1.9 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 Nucleoplasmin Spt5_N PF11942.3 KXX74338.1 - 0.26 11.9 10.9 0.47 11.1 4.0 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HisKA PF00512.20 KXX74338.1 - 0.45 10.5 4.7 0.35 10.8 1.0 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Peptidase_M1 PF01433.15 KXX74339.1 - 1.6e-05 24.1 0.0 0.11 11.5 0.0 3.1 3 0 0 3 3 3 2 Peptidase family M1 Aldedh PF00171.17 KXX74340.1 - 7.5e-135 449.8 0.0 9.1e-135 449.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX74340.1 - 0.016 13.9 0.0 0.064 11.9 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) HATPase_c PF02518.21 KXX74341.1 - 7.3e-30 102.9 0.1 1.3e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KXX74341.1 - 5.9e-24 84.4 0.0 5.7e-13 49.1 0.0 4.3 4 0 0 4 4 4 3 PAS domain HisKA PF00512.20 KXX74341.1 - 5.4e-22 77.5 0.1 1.9e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KXX74341.1 - 8e-21 74.1 0.2 1.7e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KXX74341.1 - 8.2e-20 70.7 0.1 4.1e-19 68.4 0.2 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 KXX74341.1 - 1e-19 70.5 0.1 2.4e-08 33.9 0.0 4.6 4 0 0 4 4 4 4 PAS fold PAS PF00989.19 KXX74341.1 - 5e-15 55.2 0.0 0.0013 18.4 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 KXX74341.1 - 1.6e-07 30.9 0.0 0.00057 19.6 0.0 3.6 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.1 KXX74341.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GRIP PF01465.15 KXX74341.1 - 0.23 11.0 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 GRIP domain Gly-rich_Ago1 PF12764.2 KXX74342.1 - 0.47 11.1 6.8 0.85 10.2 1.7 2.4 2 0 0 2 2 2 0 Glycine-rich region of argonaut Asp PF00026.18 KXX74343.1 - 1.3e-69 234.8 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX74343.1 - 3.3e-05 23.9 0.0 0.00014 21.8 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KXX74343.1 - 0.0053 16.3 0.3 0.04 13.4 0.0 2.4 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KXX74343.1 - 0.0058 17.1 0.1 0.51 10.8 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease WLM PF08325.5 KXX74344.1 - 2.6e-32 112.2 0.0 5.1e-32 111.2 0.0 1.5 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 KXX74344.1 - 9.4e-06 24.6 0.8 1.6e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KXX74344.1 - 0.00024 20.9 0.1 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF2477 PF10631.4 KXX74345.1 - 0.73 10.0 4.1 1.4 9.1 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) AMP-binding PF00501.23 KXX74346.1 - 7.4e-69 232.1 0.1 9e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX74346.1 - 9.5e-16 58.5 0.1 2.6e-15 57.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OKR_DC_1_N PF03709.10 KXX74346.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain GFA PF04828.9 KXX74347.1 - 0.0018 18.1 0.1 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KXX74347.1 - 5.6 6.3 6.3 0.55 9.5 1.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_1 PF00232.13 KXX74348.1 - 3.4e-154 513.4 0.0 3.9e-154 513.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Xpo1 PF08389.7 KXX74349.1 - 2.7e-39 134.4 4.5 4.5e-38 130.4 0.0 3.9 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 KXX74349.1 - 0.00071 19.4 0.7 0.6 10.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Orthopox_A49R PF06489.6 KXX74349.1 - 0.022 14.7 0.1 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A49R protein NAAA-beta PF15508.1 KXX74349.1 - 0.18 12.1 1.6 1.3e+02 3.0 0.0 5.0 5 0 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SSrecog PF03531.9 KXX74350.1 - 8.9e-74 247.5 0.2 3.9e-73 245.4 0.1 1.9 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KXX74350.1 - 8.9e-25 86.5 0.0 3.8e-24 84.4 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 KXX74350.1 - 9.2 4.1 13.5 13 3.7 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M18 PF02127.10 KXX74352.1 - 3.2e-169 563.0 0.0 3.7e-169 562.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KXX74352.1 - 7.2e-05 21.6 0.0 0.00038 19.3 0.0 2.1 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Pkinase PF00069.20 KXX74353.1 - 1.3e-63 214.6 0.0 1.6e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74353.1 - 1.5e-29 102.9 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX74353.1 - 3e-06 26.4 0.0 4.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX74353.1 - 6.5e-05 22.7 0.3 0.036 13.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KXX74353.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 KXX74354.1 - 5.2e-45 153.5 0.0 7.7e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KXX74354.1 - 1.1e-05 24.9 0.9 0.0049 16.6 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KXX74354.1 - 0.0013 17.9 0.1 0.29 10.5 0.2 3.3 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KXX74354.1 - 0.0013 18.8 0.0 0.024 14.7 0.0 2.6 1 1 0 1 1 1 1 EF-hand domain pair GRAM PF02893.15 KXX74354.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 GRAM domain WSC PF01822.14 KXX74355.1 - 1e-16 60.6 19.2 3.5e-15 55.6 4.0 4.2 4 1 0 4 4 4 3 WSC domain UPF0139 PF03669.8 KXX74357.1 - 3.9e-06 26.3 0.0 4.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) HET PF06985.6 KXX74358.1 - 3e-22 79.2 0.0 5.2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) S1-P1_nuclease PF02265.11 KXX74359.1 - 1.4e-73 247.6 0.0 1.6e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.9 KXX74360.1 - 3.4e-37 125.7 15.0 1.3e-20 72.6 0.3 2.9 3 0 0 3 3 3 2 PQ loop repeat Med12 PF09497.5 KXX74361.1 - 1.6e-28 98.4 0.2 3.5e-28 97.3 0.1 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KXX74361.1 - 0.00071 18.1 0.0 0.048 12.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain TAN PF11640.3 KXX74361.1 - 0.0014 18.4 0.9 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair DUF2682 PF10909.3 KXX74361.1 - 0.2 11.9 0.2 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) Methyltransf_23 PF13489.1 KXX74362.1 - 5.2e-16 58.7 0.0 7.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74362.1 - 0.0001 22.5 0.0 0.00035 20.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74362.1 - 0.00012 21.7 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74362.1 - 0.00024 21.6 0.0 0.0014 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74362.1 - 0.0011 19.3 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74362.1 - 0.0039 17.6 0.0 0.016 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KXX74362.1 - 0.004 16.3 0.0 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase MTS PF05175.9 KXX74362.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 KXX74362.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) WSC PF01822.14 KXX74363.1 - 0.0027 17.5 2.2 0.008 16.0 1.6 1.9 1 0 0 1 1 1 1 WSC domain FAD_binding_4 PF01565.18 KXX74364.1 - 9.2e-16 57.5 0.9 1.3e-15 57.0 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 KXX74364.1 - 1.5e-10 41.1 0.3 9.7e-09 35.1 0.2 2.3 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Dehydratase_LU PF02286.10 KXX74365.1 - 0.0026 16.0 0.1 0.0037 15.5 0.1 1.1 1 0 0 1 1 1 1 Dehydratase large subunit WD40 PF00400.27 KXX74366.1 - 0.0035 17.1 1.2 0.32 10.9 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.1 KXX74366.1 - 0.0068 16.6 0.3 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KXX74366.1 - 0.031 13.8 0.0 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat PEPCK_ATP PF01293.15 KXX74368.1 - 2.6e-216 718.6 0.0 3.3e-216 718.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KXX74368.1 - 0.0057 16.9 0.1 3.4 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KXX74368.1 - 0.099 12.1 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KXX74368.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX74368.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Tyrosinase PF00264.15 KXX74369.1 - 2e-39 136.0 0.2 2.7e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF766 PF05571.7 KXX74369.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF766) p450 PF00067.17 KXX74370.1 - 7.4e-64 215.9 0.0 9.9e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CK_II_beta PF01214.13 KXX74371.1 - 8.7e-77 256.7 0.0 1.4e-76 256.1 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PBP1_TM PF14812.1 KXX74371.1 - 5 7.4 11.5 7.2 7.0 3.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cupin_8 PF13621.1 KXX74372.1 - 5.8e-18 65.3 0.0 1.4e-17 64.0 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KXX74372.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 KXX74372.1 - 0.079 12.4 2.3 0.15 11.5 0.0 2.6 3 0 0 3 3 3 0 Cupin domain JmjC PF02373.17 KXX74372.1 - 0.14 12.4 0.0 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF924 PF06041.6 KXX74373.1 - 3.1e-21 75.9 0.1 8.1e-21 74.6 0.1 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Mito_carr PF00153.22 KXX74374.1 - 1.9e-26 91.5 2.4 2.4e-16 59.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CDK2AP PF09806.4 KXX74374.1 - 0.024 14.9 4.8 0.059 13.6 3.3 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NPR3 PF03666.8 KXX74374.1 - 0.04 12.4 3.0 0.055 12.0 2.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TMEM52 PF14979.1 KXX74374.1 - 0.057 13.3 3.1 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 Transmembrane 52 SpoIIIAH PF12685.2 KXX74374.1 - 0.55 9.7 4.0 0.93 8.9 2.8 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Neuro_bHLH PF12533.3 KXX74374.1 - 1.1 10.0 9.3 2.3 9.0 6.1 1.9 1 1 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Complex1_LYR PF05347.10 KXX74375.1 - 4.1e-07 29.7 2.6 6.8e-07 28.9 0.2 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX74375.1 - 0.0042 17.2 6.5 0.063 13.4 4.5 2.2 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L24e PF01246.15 KXX74375.1 - 0.31 10.9 1.6 1.1 9.1 0.8 1.9 1 1 1 2 2 2 0 Ribosomal protein L24e AAA PF00004.24 KXX74376.1 - 3e-20 72.7 0.0 5.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX74376.1 - 0.00058 20.0 0.3 0.038 14.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KXX74376.1 - 0.002 18.4 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX74376.1 - 0.004 16.8 0.1 0.015 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX74376.1 - 0.012 15.5 2.2 0.071 13.0 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KXX74376.1 - 0.019 15.8 0.0 0.059 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KXX74376.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX74376.1 - 0.026 14.2 0.1 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KXX74376.1 - 0.04 13.3 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KXX74376.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KXX74376.1 - 0.16 11.0 0.1 0.34 9.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 KXX74376.1 - 0.3 10.1 1.1 1.4 7.9 0.2 2.1 1 1 1 2 2 2 0 KaiC Chs3p PF12271.3 KXX74377.1 - 4.9e-106 353.9 0.7 5.7e-106 353.7 0.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4149 PF13664.1 KXX74377.1 - 1 9.4 20.0 2.6 8.1 0.2 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Cytochrom_B561 PF03188.11 KXX74378.1 - 6.4e-18 64.8 6.0 1.1e-17 64.1 4.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 KXX74378.1 - 0.0068 16.4 12.8 0.89 9.5 6.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) DUF588 PF04535.7 KXX74378.1 - 0.011 15.3 0.9 0.018 14.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) PepSY_TM_1 PF13172.1 KXX74378.1 - 0.014 15.1 0.1 0.014 15.1 0.1 3.2 3 0 0 3 3 3 0 PepSY-associated TM helix ABC2_membrane_5 PF13346.1 KXX74378.1 - 0.023 13.9 1.6 0.033 13.4 0.2 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2162 PF09930.4 KXX74378.1 - 0.088 11.9 3.4 0.11 11.6 0.9 2.0 1 1 1 2 2 2 0 Predicted transporter (DUF2162) Allantoicase PF03561.10 KXX74379.1 - 1e-107 356.2 0.1 4.3e-58 195.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Acetyltransf_3 PF13302.1 KXX74380.1 - 3e-09 37.1 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX74380.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.11 KXX74380.1 - 0.005 16.4 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Ilarvirus coat protein HET PF06985.6 KXX74381.1 - 3.4e-27 95.3 0.0 5.3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EcKinase PF02958.15 KXX74382.1 - 3.7e-19 68.9 0.0 1.5e-12 47.2 0.2 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 KXX74382.1 - 5.4e-09 36.1 2.3 8.3e-09 35.5 1.6 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KXX74382.1 - 2.5e-08 33.0 0.1 4.1e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DIL PF01843.14 KXX74383.1 - 1.7e-20 72.8 1.6 3.2e-18 65.5 1.1 2.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 KXX74383.1 - 1.2e-18 67.2 0.1 3.9e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74383.1 - 7.1e-16 57.1 0.1 2.2e-06 27.1 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KXX74383.1 - 1e-14 54.5 0.1 1.5e-07 31.7 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX74383.1 - 7.5e-13 48.2 0.1 2.8e-05 24.1 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74383.1 - 1.1e-09 37.5 0.1 0.028 14.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Sugar_tr PF00083.19 KXX74384.1 - 8.6e-100 334.4 16.8 1.2e-99 333.9 11.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX74384.1 - 2.5e-28 98.7 16.8 2.5e-28 98.7 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX74384.1 - 4.4e-07 28.6 22.9 0.0002 19.8 4.0 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KXX74384.1 - 0.0049 15.5 1.2 0.0077 14.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KXX74384.1 - 0.48 8.4 5.0 2.6 6.0 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector p450 PF00067.17 KXX74385.1 - 2.3e-21 75.8 0.0 8.5e-21 74.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Beta_elim_lyase PF01212.16 KXX74386.1 - 6.7e-56 189.5 2.5 9.6e-55 185.7 1.8 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KXX74386.1 - 9.8e-08 31.4 0.8 2.7e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KXX74386.1 - 7e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX74386.1 - 0.035 12.8 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-V MFS_1 PF07690.11 KXX74387.1 - 1.1e-24 86.8 25.5 1.1e-24 86.8 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74387.1 - 3.1e-15 55.7 5.0 3.1e-15 55.7 3.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KXX74387.1 - 0.00013 20.3 0.5 0.0012 17.1 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4360 PF14273.1 KXX74388.1 - 5.7e-31 107.5 0.0 7e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) bZIP_Maf PF03131.12 KXX74389.1 - 0.042 14.1 1.4 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Acetyltransf_7 PF13508.1 KXX74390.1 - 9.2e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX74390.1 - 0.00023 21.1 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX74390.1 - 0.0026 17.8 0.1 0.0075 16.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KXX74392.1 - 0.00024 20.7 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KXX74392.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain F-box PF00646.28 KXX74392.1 - 0.61 9.8 0.0 0.61 9.8 0.0 2.4 3 0 0 3 3 3 0 F-box domain FAD_binding_4 PF01565.18 KXX74393.1 - 1.6e-23 82.6 5.2 2.6e-23 82.0 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX74393.1 - 2.4e-12 46.5 0.3 5.5e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like RNA_pol_L_2 PF13656.1 KXX74393.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain PHD PF00628.24 KXX74394.1 - 2.6e-10 39.8 7.7 4.3e-10 39.1 5.3 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KXX74394.1 - 2.7e-05 24.3 3.4 5.2e-05 23.4 0.1 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF1751 PF08551.5 KXX74395.1 - 7.2e-05 23.0 0.1 0.00013 22.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KXX74395.1 - 9.6e-05 22.4 1.1 9.6e-05 22.4 0.8 2.0 2 1 0 2 2 2 1 Rhomboid family Gly-zipper_YMGG PF13441.1 KXX74395.1 - 0.029 13.8 0.3 9.6 5.8 0.0 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KXX74395.1 - 0.075 12.6 3.0 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Glycine zipper Transgly_assoc PF04226.8 KXX74395.1 - 1.8 8.6 9.5 3.1 7.9 0.1 3.3 3 0 0 3 3 3 0 Transglycosylase associated protein Uds1 PF15456.1 KXX74396.1 - 9.5e-45 151.5 10.5 9.5e-45 151.5 7.2 7.8 5 3 2 7 7 7 2 Up-regulated During Septation G-gamma PF00631.17 KXX74396.1 - 0.23 11.1 0.1 0.23 11.1 0.0 5.3 6 1 1 7 7 7 0 GGL domain DUF1117 PF06547.7 KXX74396.1 - 0.28 11.2 5.5 11 6.2 0.4 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) FlaC_arch PF05377.6 KXX74396.1 - 1.3 8.9 27.4 5.5 6.9 0.5 8.2 7 2 1 8 8 8 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KXX74396.1 - 1.8 8.3 35.5 0.31 10.8 1.0 6.8 6 2 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus IL11 PF07400.6 KXX74396.1 - 3.4 7.1 5.6 2.9 7.3 0.2 3.3 3 1 0 3 3 3 0 Interleukin 11 TAF4 PF05236.9 KXX74397.1 - 0.2 10.8 0.0 5.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KXX74398.1 - 2e-78 262.6 0.0 1.2e-76 256.8 0.0 2.2 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KXX74398.1 - 1e-32 112.6 0.0 1.1e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KXX74398.1 - 4.5e-14 52.5 0.7 8.7e-14 51.6 0.5 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KXX74398.1 - 6.8e-13 48.5 1.1 3.1e-12 46.4 0.5 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KXX74398.1 - 2.7e-07 30.2 0.1 5.4e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KXX74398.1 - 3.7e-06 26.7 0.2 9.4e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 KXX74399.1 - 0.0026 17.0 9.5 0.059 12.6 6.6 2.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Tcp11 PF05794.8 KXX74400.1 - 1.1e-82 278.1 0.0 9e-79 265.2 0.4 2.1 2 0 0 2 2 2 2 T-complex protein 11 V_ATPase_I PF01496.14 KXX74401.1 - 0 1020.0 0.0 0 1019.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 KXX74401.1 - 0.026 13.9 8.3 0.31 10.4 0.2 2.6 2 1 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 KXX74401.1 - 0.16 10.3 2.0 1.7 6.9 0.3 2.0 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KXX74401.1 - 0.2 8.9 5.0 0.091 10.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 KXX74401.1 - 0.35 11.3 3.6 3.2 8.2 0.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 KXX74401.1 - 0.69 9.0 4.1 0.95 8.6 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 KXX74401.1 - 0.72 9.6 4.8 10 5.9 0.8 2.3 2 0 0 2 2 2 0 Laminin Domain II CCDC-167 PF15188.1 KXX74401.1 - 1.2 9.1 4.5 16 5.5 0.1 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 KXX74401.1 - 1.2 8.6 8.0 0.34 10.4 0.2 3.1 3 0 0 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.15 KXX74401.1 - 4.5 7.0 6.6 7.9 6.2 1.3 2.7 2 1 0 2 2 2 0 Prefoldin subunit DUF1515 PF07439.6 KXX74401.1 - 5.4 6.8 7.6 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) F-box-like PF12937.2 KXX74402.1 - 0.0036 17.0 0.1 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KXX74402.1 - 0.098 12.7 0.3 23 5.4 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Prenyltransf PF01255.14 KXX74403.1 - 8.7e-88 293.1 0.0 3.5e-87 291.2 0.0 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase MSA-2c PF12238.3 KXX74403.1 - 0.84 9.2 2.3 1.1 8.8 1.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Zn_clus PF00172.13 KXX74404.1 - 2.5e-07 30.5 9.0 2.5e-07 30.5 6.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KXX74405.1 - 5.2e-77 258.5 0.0 6.8e-77 258.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74405.1 - 1.9e-37 128.7 0.0 2.8e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KXX74405.1 - 9.7e-17 60.8 1.8 1.3e-16 60.5 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KXX74405.1 - 6e-06 25.4 0.0 2.3e-05 23.5 0.0 1.8 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KXX74405.1 - 0.00027 20.3 0.2 0.00055 19.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KXX74405.1 - 0.0036 15.9 0.1 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KXX74405.1 - 0.027 14.2 1.2 0.32 10.6 0.4 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hydantoinase_B PF02538.9 KXX74406.1 - 3.3e-196 652.5 0.3 2.1e-193 643.3 0.2 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KXX74406.1 - 1e-94 316.9 0.8 1.6e-94 316.2 0.6 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KXX74406.1 - 3e-13 49.6 4.2 1.1e-12 47.8 0.2 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF92 PF01940.11 KXX74408.1 - 2.4e-70 236.2 4.6 3.3e-70 235.7 3.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Abi PF02517.11 KXX74408.1 - 0.14 12.3 1.6 22 5.2 0.8 2.7 1 1 1 2 2 2 0 CAAX protease self-immunity DUF2298 PF10060.4 KXX74408.1 - 0.19 10.5 3.9 0.23 10.2 0.7 1.9 1 1 0 2 2 2 0 Uncharacterized membrane protein (DUF2298) Fungal_trans PF04082.13 KXX74409.1 - 4.3e-05 22.5 1.8 6.9e-05 21.8 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain FCP1_C PF09309.5 KXX74410.1 - 0.0083 15.4 0.6 0.015 14.6 0.4 1.4 1 0 0 1 1 1 1 FCP1, C-terminal WD40 PF00400.27 KXX74411.1 - 7.4e-26 89.0 10.6 7e-09 35.2 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KXX74411.1 - 0.00065 17.9 0.5 0.16 10.0 0.0 2.9 1 1 0 3 3 3 2 Nucleoporin Nup120/160 Choline_kin_N PF04428.9 KXX74412.1 - 0.024 14.1 0.1 8.2 5.9 0.0 3.0 3 0 0 3 3 3 0 Choline kinase N terminus Excalibur PF05901.6 KXX74412.1 - 2.2 8.7 7.4 55 4.2 0.1 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain YpzI PF14140.1 KXX74412.1 - 2.8 7.5 10.7 14 5.2 0.1 4.1 4 0 0 4 4 4 0 YpzI-like protein MARVEL PF01284.18 KXX74413.1 - 9.7e-18 64.3 17.2 1.2e-17 64.1 12.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 KXX74413.1 - 0.05 13.1 2.7 0.16 11.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) 7TM_GPCR_Srx PF10328.4 KXX74413.1 - 0.075 12.1 1.0 0.087 11.9 0.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4449 PF14613.1 KXX74415.1 - 0.00024 21.0 1.3 0.0004 20.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 KXX74415.1 - 0.057 13.0 0.0 0.26 10.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF1828 HAD_2 PF13419.1 KXX74415.1 - 0.11 12.7 2.5 0.14 12.3 0.5 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Patatin PF01734.17 KXX74416.1 - 5.4e-23 82.0 0.0 1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.3 KXX74417.1 - 3.7e-13 48.8 0.0 7.2e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74417.1 - 9.4e-05 22.2 14.8 0.00018 21.3 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.7 KXX74418.1 - 4.9e-44 150.1 0.0 1.2e-43 148.8 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.13 KXX74419.1 - 5e-07 29.5 13.6 7.6e-07 28.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KXX74420.1 - 3.7e-36 124.6 0.0 5e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74420.1 - 4.1e-14 52.2 0.0 5.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX74420.1 - 0.014 15.1 0.0 0.41 10.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Med13_C PF06333.7 KXX74420.1 - 3.8 5.9 4.6 6 5.2 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal EMP24_GP25L PF01105.19 KXX74421.1 - 3.9e-52 176.6 0.0 4.4e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 KXX74421.1 - 0.056 13.8 0.0 0.085 13.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Shugoshin_N PF07558.6 KXX74421.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Mac PF12464.3 KXX74423.1 - 4.7e-13 48.9 0.0 1.5e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KXX74423.1 - 8.7e-12 43.9 15.9 5.6e-08 31.9 0.3 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 KXX74423.1 - 3.6e-09 36.3 8.2 7.5e-09 35.3 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 KXX74423.1 - 7.9e-09 34.9 15.4 8.1e-05 22.1 0.1 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.3 KXX74423.1 - 0.033 13.5 3.9 0.061 12.6 2.7 1.4 1 0 0 1 1 1 0 Spt20 family zf-DHHC PF01529.15 KXX74423.1 - 0.32 10.3 4.0 6.4 6.1 0.3 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase LIM_bind PF01803.11 KXX74423.1 - 4.1 6.4 7.4 6.7 5.7 5.1 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Adap_comp_sub PF00928.16 KXX74426.1 - 6e-64 215.6 0.0 1.4e-63 214.4 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Glyco_hydro_6 PF01341.12 KXX74427.1 - 1.2e-99 333.5 0.2 1.4e-99 333.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 KXX74427.1 - 0.037 12.4 0.0 0.057 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 DUF4536 PF15055.1 KXX74428.1 - 1.4e-06 28.2 0.4 2.1e-06 27.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) NAD_binding_8 PF13450.1 KXX74428.1 - 0.013 15.5 0.3 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OST3_OST6 PF04756.8 KXX74429.1 - 3.4e-20 72.2 0.1 4.8e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Abi PF02517.11 KXX74429.1 - 0.15 12.2 2.4 0.39 10.8 1.7 1.7 1 1 0 1 1 1 0 CAAX protease self-immunity Thioredoxin PF00085.15 KXX74429.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF4267 PF14087.1 KXX74431.1 - 1.1e-13 50.7 3.7 1.3e-13 50.5 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Peptidase_M28 PF04389.12 KXX74432.1 - 1.3e-22 80.4 0.1 5.5e-16 58.8 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M28 Peptidase_M20 PF01546.23 KXX74432.1 - 0.0029 17.1 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 zf-CCHC PF00098.18 KXX74434.1 - 2.3e-11 43.0 11.0 1.6e-05 24.5 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KXX74434.1 - 4.7e-09 35.7 0.2 9.6e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KXX74434.1 - 4.3e-06 26.3 7.1 0.0015 18.2 2.5 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KXX74434.1 - 5.5e-06 25.9 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.1 KXX74434.1 - 0.00087 18.7 0.8 0.00087 18.7 0.6 3.6 3 1 1 4 4 4 1 Zinc knuckle zf-CCHC_4 PF14392.1 KXX74434.1 - 0.0022 17.6 7.8 0.3 10.7 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KXX74434.1 - 0.0036 16.9 8.7 0.071 12.7 0.3 2.7 1 1 1 2 2 2 2 Zinc knuckle FliT PF05400.8 KXX74434.1 - 0.49 10.8 2.7 28 5.2 0.4 3.3 4 0 0 4 4 4 0 Flagellar protein FliT BBE PF08031.7 KXX74435.1 - 2.7e-10 39.9 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX74435.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FKBP_C PF00254.23 KXX74436.1 - 2e-37 127.0 0.0 2.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.13 KXX74437.1 - 6.3e-33 113.7 0.0 8.5e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.13 KXX74438.1 - 0.0041 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.5 KXX74439.1 - 3.3e-87 291.6 8.1 5.6e-87 290.9 5.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KXX74439.1 - 7.5e-26 90.1 0.1 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 KXX74439.1 - 0.011 14.6 6.1 0.019 13.8 3.9 1.6 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.4 KXX74439.1 - 0.021 14.0 0.7 0.13 11.4 0.5 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.8 KXX74439.1 - 0.083 12.2 3.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Arfaptin-like domain MBOAT PF03062.14 KXX74440.1 - 1.1e-33 116.7 11.4 2.1e-33 115.8 7.4 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 KXX74441.1 - 5.8e-48 163.3 0.0 3e-47 160.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74441.1 - 1.6e-26 92.9 0.0 2.8e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX74441.1 - 0.16 10.8 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like HSP90 PF00183.13 KXX74442.1 - 1.7e-258 858.3 36.1 2.1e-258 858.0 25.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KXX74442.1 - 2.4e-12 46.5 0.1 4.4e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KXX74442.1 - 1.9e-11 43.7 0.6 1.9e-11 43.7 0.4 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KXX74442.1 - 0.032 14.5 0.7 0.032 14.5 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KXX74442.1 - 0.23 11.2 3.1 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Tumour suppressor protein Peptidase_S10 PF00450.17 KXX74442.1 - 0.47 9.5 0.0 0.47 9.5 0.0 2.3 1 1 1 2 2 2 0 Serine carboxypeptidase GST_N_3 PF13417.1 KXX74443.1 - 5.6e-14 52.1 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX74443.1 - 4.1e-11 42.7 0.0 8.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX74443.1 - 1.2e-10 41.4 0.0 3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX74443.1 - 2.2e-10 40.3 0.0 4.3e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX74443.1 - 2.7e-10 39.9 0.0 4.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX74443.1 - 9.3e-10 38.8 0.2 2.1e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Med11 PF10280.4 KXX74444.1 - 1.1e-31 109.2 0.8 3.9e-31 107.5 0.6 1.9 1 1 0 1 1 1 1 Mediator complex protein Activator_LAG-3 PF11498.3 KXX74444.1 - 0.43 9.2 14.1 0.94 8.1 8.5 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pex14_N PF04695.8 KXX74444.1 - 1.2 9.2 5.9 0.52 10.3 0.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 KXX74444.1 - 2.3 6.9 13.6 4.2 6.1 9.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 KXX74445.1 - 2.5e-50 166.6 23.2 1e-08 34.6 0.5 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KXX74445.1 - 1.3e-45 154.9 0.1 2e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 KXX74445.1 - 4.4e-05 23.2 0.1 0.0023 17.6 0.0 3.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KXX74445.1 - 0.0012 17.7 0.1 0.25 10.0 0.0 2.8 2 2 0 2 2 2 2 Nup133 N terminal like LisH PF08513.6 KXX74445.1 - 0.0054 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KXX74445.1 - 0.01 14.0 0.6 4.8 5.1 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 IKI3 PF04762.7 KXX74445.1 - 0.083 10.6 0.1 0.28 8.9 0.0 1.9 2 1 0 2 2 2 0 IKI3 family PAN_4 PF14295.1 KXX74446.1 - 2.3e-07 30.4 0.3 4.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 PAN domain MANEC PF07502.9 KXX74446.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 MANEC domain Cytochrom_B_N PF00033.14 KXX74446.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PAN_1 PF00024.21 KXX74446.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 PAN domain Beta-lactamase PF00144.19 KXX74447.1 - 5.4e-39 134.1 0.0 8e-38 130.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase F-box-like PF12937.2 KXX74448.1 - 1.5e-07 31.0 0.1 9e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KXX74448.1 - 0.034 13.8 1.5 0.18 11.4 1.0 2.3 1 1 0 1 1 1 0 F-box domain LRR_8 PF13855.1 KXX74448.1 - 0.072 12.8 0.1 1.1 9.0 0.1 2.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 KXX74448.1 - 0.17 12.2 1.6 1.1e+02 3.7 0.2 4.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KXX74448.1 - 0.3 11.2 3.6 59 4.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat APH PF01636.18 KXX74450.1 - 1.8e-13 50.7 0.8 3.4e-13 49.8 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX74450.1 - 0.00096 18.2 0.0 0.77 8.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KXX74450.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBM_19 PF03427.8 KXX74451.1 - 0.47 10.2 8.6 1.8 8.4 6.0 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) TFIIA PF03153.8 KXX74452.1 - 0.0011 18.9 15.9 0.0014 18.5 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 KXX74452.1 - 0.049 13.2 3.6 0.069 12.7 2.5 1.2 1 0 0 1 1 1 0 IncA protein Dapper PF15268.1 KXX74452.1 - 1.4 7.6 24.7 1.9 7.1 17.1 1.0 1 0 0 1 1 1 0 Dapper Macoilin PF09726.4 KXX74452.1 - 3.7 5.7 12.4 4.9 5.3 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein LUC7 PF03194.10 KXX74453.1 - 6e-69 232.3 0.1 7.2e-69 232.1 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 KXX74453.1 - 0.028 15.1 0.6 0.13 13.0 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain zf-C4H2 PF10146.4 KXX74453.1 - 0.036 14.1 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HR1 PF02185.11 KXX74453.1 - 0.11 12.2 0.2 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Hr1 repeat Gpi16 PF04113.9 KXX74454.1 - 5.6e-244 810.3 0.0 7.1e-244 810.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF3716 PF12511.3 KXX74455.1 - 4.4e-15 55.0 5.0 4.4e-15 55.0 3.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) HET PF06985.6 KXX74456.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Nuc_deoxyrib_tr PF05014.10 KXX74457.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Sushi PF00084.15 KXX74457.1 - 0.032 14.5 0.1 0.072 13.4 0.1 1.5 1 0 0 1 1 1 0 Sushi domain (SCR repeat) DUF434 PF04256.7 KXX74457.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) OppC_N PF12911.2 KXX74458.1 - 0.13 11.6 1.2 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Abhydrolase_4 PF08386.5 KXX74459.1 - 4.6e-22 77.8 0.0 9.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX74459.1 - 1.2e-15 57.7 0.0 6.2e-14 52.1 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX74459.1 - 3.3e-09 36.9 1.5 1.2e-08 35.0 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 KXX74460.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Esterase_phd PF10503.4 KXX74461.1 - 4e-07 29.5 0.1 1.3e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KXX74461.1 - 1.4e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KXX74461.1 - 1.5e-05 24.5 0.1 4.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KXX74461.1 - 2e-05 23.9 0.1 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KXX74461.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX74461.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX74461.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 KXX74461.1 - 0.018 13.5 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pkinase PF00069.20 KXX74462.1 - 5.8e-20 71.5 0.0 1.7e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74462.1 - 1.2e-05 24.5 0.0 0.11 11.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 KXX74463.1 - 2.9e-60 203.8 0.0 4.2e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX74463.1 - 1.2e-36 126.3 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX74463.1 - 3.7e-06 26.7 0.0 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3180 PF11377.3 KXX74464.1 - 0.16 11.8 0.3 0.16 11.8 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) DUF3328 PF11807.3 KXX74465.1 - 4e-27 95.3 0.0 5.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.6 KXX74466.1 - 1.1e-19 70.9 0.0 2.2e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GRIM-19 PF06212.7 KXX74467.1 - 3.2e-22 78.6 0.0 6.2e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.13 KXX74468.1 - 5.4e-27 94.4 0.1 2.9e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KXX74468.1 - 2.9e-06 27.0 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KXX74468.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 KXX74468.1 - 0.0081 15.7 0.0 4.8 6.9 0.0 2.9 1 1 1 2 2 2 2 Biotin-requiring enzyme IncA PF04156.9 KXX74468.1 - 1.6 8.2 8.9 1.1 8.8 3.2 2.6 2 0 0 2 2 2 0 IncA protein NACHT PF05729.7 KXX74469.1 - 3.7e-10 39.6 0.0 9.7e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX74469.1 - 4.5e-07 30.0 0.0 0.00012 22.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KXX74469.1 - 4.8e-06 26.6 0.1 4e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KXX74469.1 - 0.0007 19.1 0.1 0.015 14.7 0.0 2.8 4 0 0 4 4 4 1 AAA-like domain AAA_29 PF13555.1 KXX74469.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KXX74469.1 - 0.026 13.3 0.2 0.32 9.8 0.2 2.6 1 1 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KXX74469.1 - 0.029 14.6 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 KXX74469.1 - 0.043 13.6 2.7 2.4 7.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KXX74469.1 - 0.076 13.8 0.1 0.63 10.8 0.0 2.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KXX74469.1 - 0.086 13.1 0.1 1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KXX74469.1 - 0.11 12.7 1.2 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KXX74469.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase E1-E2_ATPase PF00122.15 KXX74470.1 - 1.1e-53 181.6 0.5 1.1e-53 181.6 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX74470.1 - 1.5e-43 148.4 6.2 5.3e-43 146.6 2.4 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KXX74470.1 - 1e-19 70.2 0.0 2.5e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KXX74470.1 - 2.2e-18 67.4 0.0 7.9e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX74470.1 - 8.2e-08 32.6 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX74470.1 - 0.021 14.2 0.2 0.13 11.7 0.0 2.5 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KXX74470.1 - 0.023 14.2 0.1 7.9 5.9 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 KXX74470.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) DUF202 PF02656.10 KXX74470.1 - 0.57 10.4 2.6 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) BNR_2 PF13088.1 KXX74471.1 - 1.9e-05 24.0 0.1 0.0053 16.0 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KXX74471.1 - 6 7.1 5.8 3.7 7.7 0.4 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat IBN_N PF03810.14 KXX74472.1 - 2.3e-15 56.2 0.4 1.2e-14 53.9 0.3 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KXX74472.1 - 0.00024 21.0 0.8 0.013 15.4 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein tRNA-synt_1g PF09334.6 KXX74473.1 - 2.3e-10 39.7 0.0 8.3e-10 37.8 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KXX74473.1 - 2.2e-05 24.2 0.3 4.4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KXX74473.1 - 6e-05 22.3 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 KXX74473.1 - 0.00016 19.8 0.0 0.00022 19.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Pex2_Pex12 PF04757.9 KXX74474.1 - 5e-42 143.8 0.3 8.5e-42 143.1 0.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KXX74474.1 - 0.00095 19.0 4.2 0.0019 18.0 2.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KXX74474.1 - 0.025 14.2 0.6 0.12 12.0 0.4 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KXX74474.1 - 0.057 13.4 6.9 0.034 14.1 1.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) M_domain PF12938.2 KXX74474.1 - 0.43 10.3 6.4 0.12 12.1 2.2 1.6 1 1 0 1 1 1 0 M domain of GW182 NAD_binding_6 PF08030.7 KXX74475.1 - 1.3e-24 86.8 0.0 2.2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KXX74475.1 - 1.2e-23 83.0 0.0 2.5e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KXX74475.1 - 1.6e-18 66.9 9.6 1.6e-18 66.9 6.7 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KXX74475.1 - 0.00015 21.7 0.0 0.00039 20.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KXX74475.1 - 0.05 14.1 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain LrgA PF03788.9 KXX74475.1 - 0.12 12.1 1.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 LrgA family 3HCDH_N PF02737.13 KXX74476.1 - 1.4e-23 83.4 0.0 2.8e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KXX74476.1 - 0.064 12.9 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KXX74476.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KXX74476.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Hemerythrin PF01814.18 KXX74477.1 - 6.8e-14 52.1 0.4 8.6e-14 51.8 0.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactamase_B PF00753.22 KXX74478.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_transf_90 PF05686.7 KXX74479.1 - 1.7e-09 36.9 0.3 0.0062 15.2 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 zf-DHHC PF01529.15 KXX74480.1 - 1.1e-34 119.3 0.0 1.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KXX74480.1 - 1.2 8.9 5.6 0.25 11.1 1.1 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily Myosin_head PF00063.16 KXX74481.1 - 2.1e-231 769.7 2.7 3.3e-231 769.1 1.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KXX74481.1 - 2.4e-40 137.9 0.0 6.4e-40 136.5 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KXX74481.1 - 4e-12 45.3 0.2 7.4e-12 44.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX74481.1 - 9.8e-11 41.0 0.1 2.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX74481.1 - 3.1e-08 32.9 0.0 7.5e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KXX74481.1 - 0.0011 18.3 10.5 0.04 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KXX74481.1 - 0.0053 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 KXX74481.1 - 0.007 15.6 0.1 2.9 7.1 0.0 2.3 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KXX74481.1 - 0.019 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF552 PF04472.7 KXX74481.1 - 0.021 14.6 0.0 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 KXX74481.1 - 0.051 14.3 0.0 0.19 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KXX74481.1 - 0.092 12.4 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KXX74481.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1_like PF12832.2 KXX74482.1 - 7.8e-20 70.4 0.2 7.8e-20 70.4 0.1 2.5 3 0 0 3 3 3 1 MFS_1 like family Cytochrom_B558a PF05038.8 KXX74482.1 - 0.018 14.6 0.7 0.018 14.6 0.5 1.8 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit CENP-B_dimeris PF09026.5 KXX74482.1 - 0.45 10.7 4.6 0.84 9.9 3.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KXX74482.1 - 2.5 7.6 6.3 4.2 6.8 4.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin COesterase PF00135.23 KXX74483.1 - 1.3e-74 251.8 0.0 2e-74 251.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX74483.1 - 2e-08 34.0 0.0 4.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX74483.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Gly_kinase PF02595.10 KXX74486.1 - 7e-105 350.8 4.1 8e-105 350.6 2.9 1.0 1 0 0 1 1 1 1 Glycerate kinase family PucR PF07905.6 KXX74486.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family MFS_1 PF07690.11 KXX74487.1 - 3.1e-42 144.5 17.8 3.1e-42 144.5 12.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74487.1 - 3.4e-15 55.5 1.0 3.4e-15 55.5 0.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KXX74487.1 - 1.5e-09 36.5 2.0 3.6e-06 25.3 0.1 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 KXX74487.1 - 0.00056 18.2 0.8 0.00082 17.6 0.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KXX74487.1 - 0.02 13.0 3.3 0.025 12.6 1.5 1.7 1 1 0 2 2 2 0 Transmembrane secretion effector HET PF06985.6 KXX74488.1 - 7.7e-29 100.6 0.0 1.3e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 KXX74489.1 - 3.9e-64 216.4 0.1 4.6e-64 216.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CAS_CSE1 PF03378.10 KXX74491.1 - 4.3e-175 582.2 0.0 9.9e-175 581.0 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KXX74491.1 - 6e-151 502.1 2.3 4.5e-150 499.3 2.5 1.8 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 KXX74491.1 - 1.8e-11 43.7 0.0 5.7e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KXX74491.1 - 0.0049 17.1 0.2 0.064 13.5 0.0 2.8 3 0 0 3 3 3 1 HEAT repeats Xpo1 PF08389.7 KXX74491.1 - 0.015 15.2 0.7 1.3 8.8 0.0 3.5 3 1 0 3 3 3 0 Exportin 1-like protein DUF3384 PF11864.3 KXX74492.1 - 5.8e-114 381.0 0.0 1.1e-113 380.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KXX74492.1 - 3.1e-54 183.2 0.0 6.1e-54 182.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KXX74492.1 - 8.2e-33 113.9 1.8 6.1e-30 104.4 0.1 2.6 2 0 0 2 2 2 2 Tuberin WD40 PF00400.27 KXX74493.1 - 4e-24 83.5 12.0 3.5e-06 26.6 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 KXX74493.1 - 2.6e-07 30.5 0.1 1.1e-05 25.2 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KXX74493.1 - 0.001 18.6 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat CLTH PF10607.4 KXX74493.1 - 0.0029 17.3 0.0 0.0083 15.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Gmad1 PF10647.4 KXX74493.1 - 0.0052 16.2 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 KXX74493.1 - 0.0062 15.8 0.0 2.5 7.5 0.0 2.7 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature ParBc_2 PF08857.6 KXX74493.1 - 0.034 13.9 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative ParB-like nuclease DUF2745 PF10922.3 KXX74493.1 - 0.041 13.8 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) Dynamin_M PF01031.15 KXX74494.1 - 1.2e-107 359.0 0.6 2.4e-107 358.1 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KXX74494.1 - 7.1e-57 191.8 0.0 1.4e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KXX74494.1 - 1e-28 99.0 6.9 1.1e-28 98.8 3.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KXX74494.1 - 3.6e-05 23.6 0.2 0.00048 20.0 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX74494.1 - 0.013 15.9 0.0 0.039 14.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Tombus_P19 PF03220.8 KXX74495.1 - 7 5.9 8.0 15 4.8 0.8 3.1 3 0 0 3 3 3 0 Tombusvirus P19 core protein Pkinase PF00069.20 KXX74496.1 - 2.8e-49 167.6 0.0 4.9e-48 163.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74496.1 - 9.5e-24 83.8 0.0 4.7e-17 61.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KXX74496.1 - 2.3e-06 26.7 0.1 0.00018 20.5 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.19 KXX74496.1 - 0.0019 18.6 1.1 0.0043 17.5 0.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 KXX74496.1 - 0.0068 16.1 0.9 0.34 10.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX74496.1 - 0.029 13.4 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KXX74496.1 - 0.058 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KXX74496.1 - 0.079 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family G_glu_transpept PF01019.16 KXX74497.1 - 3.3e-133 444.8 0.0 5.4e-133 444.1 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CoA_transf_3 PF02515.12 KXX74498.1 - 1.1e-48 165.0 0.0 1.4e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Glutaredoxin PF00462.19 KXX74499.1 - 8e-16 57.7 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin OPT PF03169.10 KXX74500.1 - 1.2e-143 479.8 47.2 1.4e-143 479.6 32.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPR_16 PF13432.1 KXX74500.1 - 0.15 12.7 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat p450 PF00067.17 KXX74501.1 - 1.7e-51 175.2 0.0 2.2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KXX74502.1 - 4.1e-63 212.4 8.2 9.1e-63 211.3 5.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX74502.1 - 3.5e-33 114.6 0.9 3.5e-33 114.6 0.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX74502.1 - 1.3e-21 78.0 1.6 1.5e-21 77.8 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX74502.1 - 4e-17 61.4 0.0 4e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KXX74502.1 - 7.9e-15 54.5 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX74502.1 - 1.4e-08 35.0 0.1 3.9e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX74502.1 - 8.1e-06 25.5 2.4 3.4e-05 23.5 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 KXX74503.1 - 3.3e-06 27.4 0.1 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KXX74503.1 - 0.016 14.4 0.2 0.019 14.2 0.2 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KXX74503.1 - 0.049 13.5 0.3 0.11 12.4 0.2 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RTA1 PF04479.8 KXX74504.1 - 2.3e-27 95.9 4.1 3e-27 95.5 2.8 1.1 1 0 0 1 1 1 1 RTA1 like protein RRP14 PF15459.1 KXX74504.1 - 0.015 15.3 3.3 0.025 14.6 2.3 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Cyto_heme_lyase PF01265.12 KXX74505.1 - 1.1e-86 290.6 0.1 1.3e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2638 PF10937.3 KXX74506.1 - 4.6e-37 127.4 0.6 5.6e-37 127.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) GHMP_kinases_N PF00288.21 KXX74507.1 - 3.2e-10 39.9 3.6 1.6e-09 37.6 1.3 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF647 PF04884.9 KXX74508.1 - 4.2e-100 334.0 0.9 5.4e-100 333.7 0.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis UbiA PF01040.13 KXX74509.1 - 3.9e-23 81.9 5.0 3.9e-23 81.9 3.4 1.8 1 1 1 2 2 2 1 UbiA prenyltransferase family p450 PF00067.17 KXX74510.1 - 4e-39 134.4 0.0 4.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_8 PF08022.7 KXX74511.1 - 1.3e-09 37.8 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KXX74511.1 - 0.0005 20.1 0.1 0.0005 20.1 0.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KXX74511.1 - 0.00064 19.6 0.0 0.0098 15.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KXX74511.1 - 0.057 13.5 0.3 0.057 13.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Acyl-CoA_dh_1 PF00441.19 KXX74512.1 - 4.5e-24 85.2 0.3 8.2e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX74512.1 - 1.6e-23 83.3 0.1 3.9e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KXX74512.1 - 2.4e-18 65.3 0.0 6.8e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KXX74512.1 - 5.6e-08 33.1 0.3 1.1e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_10 PF13374.1 KXX74513.1 - 2.2e-89 291.1 6.2 1.6e-13 50.1 0.0 8.5 7 1 1 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KXX74513.1 - 9.5e-81 265.7 7.9 6.1e-16 58.1 0.0 6.3 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 KXX74513.1 - 1.9e-25 86.5 4.7 0.0059 16.3 0.0 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KXX74513.1 - 6.3e-18 63.1 8.0 0.64 10.0 0.0 8.5 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KXX74513.1 - 1.1e-16 59.5 1.5 0.32 11.2 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_4 PF07721.9 KXX74513.1 - 2.7e-16 58.2 6.3 0.24 11.9 0.0 8.6 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX74513.1 - 1.5e-15 56.0 0.7 0.63 9.7 0.0 7.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX74513.1 - 3.1e-15 55.5 0.7 0.0089 15.6 0.1 6.0 1 1 5 6 6 6 6 TPR repeat TPR_16 PF13432.1 KXX74513.1 - 1e-13 51.5 0.0 0.011 16.3 0.0 6.3 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX74513.1 - 1.5e-12 47.6 1.6 0.11 12.8 0.0 6.8 5 2 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX74513.1 - 4.3e-10 38.6 0.3 3 7.8 0.0 6.6 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX74513.1 - 6.6e-10 38.7 13.1 2.1 9.2 0.0 9.1 7 2 2 9 9 9 1 Tetratricopeptide repeat NB-ARC PF00931.17 KXX74513.1 - 3.5e-09 35.9 0.0 9.3e-09 34.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_5 PF12688.2 KXX74513.1 - 8.7e-09 35.4 3.2 0.1 12.6 0.0 5.5 2 1 4 6 6 5 1 Tetratrico peptide repeat Apc3 PF12895.2 KXX74513.1 - 3.7e-08 33.3 0.1 0.066 13.3 0.0 4.6 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KXX74513.1 - 1e-05 25.1 3.8 20 5.4 0.0 6.7 7 0 0 7 7 6 0 PPR repeat DUF4074 PF13293.1 KXX74513.1 - 4.4e-05 23.6 0.7 24 5.2 0.0 5.5 6 1 1 7 7 5 0 Domain of unknown function (DUF4074) NACHT PF05729.7 KXX74513.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2664 PF10867.3 KXX74513.1 - 0.00012 22.6 0.5 43 4.8 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2664) TPR_6 PF13174.1 KXX74513.1 - 0.00015 21.9 12.4 22 5.7 0.0 7.8 7 1 0 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.1 KXX74513.1 - 0.00037 20.5 5.1 14 6.2 0.0 6.6 7 0 0 7 7 6 0 Pentatricopeptide repeat domain AAA_25 PF13481.1 KXX74513.1 - 0.0054 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rab5-bind PF09311.6 KXX74513.1 - 0.0096 15.8 6.1 1.5 8.6 0.2 4.0 1 1 2 3 3 3 1 Rabaptin-like protein AAA_16 PF13191.1 KXX74513.1 - 0.012 15.6 0.0 0.054 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KXX74513.1 - 0.015 15.4 0.0 0.049 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sorting_nexin PF03700.8 KXX74513.1 - 0.016 15.3 0.2 8.3 6.5 0.0 3.3 2 1 1 3 3 3 0 Sorting nexin, N-terminal domain DUF1897 PF09005.5 KXX74513.1 - 0.089 12.2 3.9 45 3.6 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) UQ_con PF00179.21 KXX74514.1 - 3.5e-52 175.5 0.0 4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX74514.1 - 0.00026 20.7 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX74514.1 - 0.0014 18.5 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KXX74514.1 - 0.01 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Arc_PepC PF06819.6 KXX74516.1 - 0.029 14.2 0.0 0.047 13.6 0.0 1.4 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain NAD_binding_6 PF08030.7 KXX74517.1 - 4.7e-31 107.8 0.0 9.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KXX74517.1 - 3.2e-20 71.9 0.0 9.8e-20 70.3 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KXX74517.1 - 1e-16 61.1 18.9 3.8e-16 59.3 6.9 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KXX74517.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain XPG_I PF00867.13 KXX74518.1 - 1.7e-30 104.9 0.6 3.5e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KXX74518.1 - 4.1e-25 87.9 0.0 4.1e-25 87.9 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KXX74518.1 - 1.2e-05 25.4 0.2 9.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 KXX74518.1 - 0.054 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Cast PF10174.4 KXX74519.1 - 0.00061 17.9 30.8 0.0016 16.6 14.8 2.0 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.3 KXX74519.1 - 0.0073 16.0 23.2 0.069 12.9 4.5 4.3 2 2 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF3166 PF11365.3 KXX74519.1 - 0.029 14.8 2.6 0.029 14.8 1.8 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3166) p450 PF00067.17 KXX74519.1 - 0.12 10.8 7.9 0.15 10.5 0.7 2.2 1 1 0 2 2 2 0 Cytochrome P450 Ribonuc_red_lgN PF00317.16 KXX74519.1 - 0.2 11.4 1.4 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Reo_sigmaC PF04582.7 KXX74519.1 - 0.52 9.4 7.1 0.48 9.5 1.0 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein SPARC_Ca_bdg PF10591.4 KXX74519.1 - 2 8.4 6.4 11 6.0 0.1 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SlyX PF04102.7 KXX74519.1 - 8.6 6.8 26.6 0.29 11.5 0.2 5.3 1 1 3 5 5 5 0 SlyX DnaJ PF00226.26 KXX74521.1 - 8.5e-10 38.2 0.0 0.0014 18.3 0.0 4.0 4 0 0 4 4 4 2 DnaJ domain Pheromone PF08015.6 KXX74521.1 - 2.1 9.2 6.1 1.9 9.4 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone Methyltransf_23 PF13489.1 KXX74522.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74522.1 - 0.00091 19.6 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Mt_ATP-synt_D PF05873.7 KXX74524.1 - 1.2e-18 67.2 1.9 1.6e-18 66.8 1.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 KXX74524.1 - 0.072 13.0 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Dor1 PF04124.7 KXX74524.1 - 0.1 11.0 1.4 0.12 10.7 0.9 1.1 1 0 0 1 1 1 0 Dor1-like family DUF4515 PF14988.1 KXX74524.1 - 0.28 10.8 3.8 2 8.0 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) RasGAP_C PF03836.10 KXX74524.1 - 0.28 10.8 2.8 0.5 10.0 0.8 2.2 1 1 1 2 2 2 0 RasGAP C-terminus NAC PF01849.13 KXX74525.1 - 4.7e-26 90.0 0.4 6.3e-25 86.4 0.1 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KXX74525.1 - 0.00045 19.9 0.2 0.0011 18.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_S13 PF00416.17 KXX74525.1 - 0.43 11.0 3.2 0.6 10.5 0.2 2.2 2 1 1 3 3 3 0 Ribosomal protein S13/S18 SpoIIIAH PF12685.2 KXX74525.1 - 1.2 8.6 13.7 0.18 11.2 3.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein FAM176 PF14851.1 KXX74525.1 - 8.7 6.0 10.7 9 5.9 1.9 2.2 2 0 0 2 2 2 0 FAM176 family Ribosomal_L14e PF01929.12 KXX74526.1 - 7e-28 96.7 0.6 1e-27 96.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Acetyltransf_9 PF13527.1 KXX74527.1 - 4.9e-06 26.4 0.1 1.4e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX74527.1 - 4.6e-05 23.4 0.1 0.00013 22.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX74527.1 - 0.00053 19.9 0.1 0.0071 16.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX74527.1 - 0.00095 19.2 0.3 0.0097 16.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PFK PF00365.15 KXX74528.1 - 7.5e-162 536.9 0.8 2.3e-119 397.5 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase SKG6 PF08693.5 KXX74529.1 - 3.1e-05 23.1 0.7 6e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Romo1 PF10247.4 KXX74529.1 - 0.037 14.2 0.5 0.071 13.3 0.4 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Podoplanin PF05808.6 KXX74529.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Podoplanin Rax2 PF12768.2 KXX74529.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SAGA-Tad1 PF12767.2 KXX74530.1 - 0.026 14.1 1.2 0.036 13.7 0.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1484 PF07363.6 KXX74530.1 - 0.03 14.6 0.6 0.055 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) DUF4559 PF15112.1 KXX74530.1 - 0.075 12.1 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SNF2_N PF00176.18 KXX74531.1 - 1.2e-63 214.6 0.6 1.8e-63 214.1 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX74531.1 - 2.9e-13 49.4 0.0 9.1e-13 47.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KXX74531.1 - 3.5e-08 32.9 2.9 6.6e-08 32.1 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX74531.1 - 3.5e-08 33.1 3.7 6.7e-08 32.2 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX74531.1 - 1.3e-07 31.4 4.2 3.1e-07 30.3 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX74531.1 - 3.7e-07 29.6 4.5 7.4e-07 28.7 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX74531.1 - 8.5e-07 28.6 3.7 1.6e-06 27.6 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX74531.1 - 1.2e-05 25.0 4.0 2.9e-05 23.8 2.8 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 KXX74531.1 - 0.0001 21.8 0.1 0.00037 20.0 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 KXX74531.1 - 0.00023 20.8 0.8 0.00047 19.8 0.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KXX74531.1 - 0.0012 18.3 1.9 0.0033 16.8 1.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 KXX74531.1 - 0.075 12.6 3.9 0.31 10.6 2.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Cwf_Cwc_15 PF04889.7 KXX74531.1 - 0.083 12.5 30.3 0.023 14.4 7.6 3.5 4 0 0 4 4 3 0 Cwf15/Cwc15 cell cycle control protein Baculo_IE-1 PF05290.6 KXX74531.1 - 0.099 12.3 0.9 0.25 11.0 0.6 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Sec8_exocyst PF04048.9 KXX74531.1 - 1.9 8.0 6.6 1.9 8.1 0.0 3.3 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain DZR PF12773.2 KXX74531.1 - 2.6 7.9 6.3 2.6 7.9 2.5 2.2 2 0 0 2 2 2 0 Double zinc ribbon Phosphodiest PF01663.17 KXX74532.1 - 3.7e-90 302.8 0.8 4.8e-90 302.5 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX74532.1 - 0.00096 18.4 0.3 0.062 12.4 0.2 2.3 1 1 0 1 1 1 1 Sulfatase ATG27 PF09451.5 KXX74532.1 - 0.045 12.9 2.3 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 Autophagy-related protein 27 Apo-CIII PF05778.7 KXX74532.1 - 0.14 11.6 1.3 0.32 10.4 0.9 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Isochorismatase PF00857.15 KXX74533.1 - 3.2e-13 49.9 0.0 4.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-C2H2_4 PF13894.1 KXX74534.1 - 0.0027 17.9 13.1 0.0077 16.5 0.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX74534.1 - 0.012 15.8 4.7 0.81 10.1 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Med3 PF11593.3 KXX74534.1 - 2.4 7.3 13.9 1.8 7.7 1.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Kinetochor_Ybp2 PF08568.5 KXX74535.1 - 4.3e-122 408.4 0.0 6e-122 408.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SET PF00856.23 KXX74536.1 - 5.1e-13 49.6 0.0 1.4e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 SET domain SAF PF08666.7 KXX74536.1 - 0.039 14.3 0.1 0.89 10.0 0.0 2.5 2 0 0 2 2 2 0 SAF domain Glyco_transf_28 PF03033.15 KXX74538.1 - 1.9e-15 56.8 0.0 5e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KXX74538.1 - 2.1e-06 26.6 0.0 3.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KXX74538.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Utp13 PF08625.6 KXX74538.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain KSHV_K1 PF11049.3 KXX74539.1 - 0.045 13.7 0.6 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus DUF3024 PF11225.3 KXX74539.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Adeno_E3_CR2 PF02439.10 KXX74539.1 - 4.5 6.9 8.6 0.16 11.5 1.5 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Zn_clus PF00172.13 KXX74540.1 - 1.1e-05 25.2 7.7 1.9e-05 24.4 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4319 PF14203.1 KXX74540.1 - 0.018 14.6 0.1 0.052 13.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) DSPc PF00782.15 KXX74542.1 - 2.3e-10 40.1 0.0 5.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TMEM154 PF15102.1 KXX74542.1 - 0.025 14.2 1.3 0.025 14.2 0.9 1.9 2 0 0 2 2 2 0 TMEM154 protein family Init_tRNA_PT PF04179.7 KXX74542.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Tho2 PF11262.3 KXX74543.1 - 1.2e-87 293.6 0.2 1.7e-87 293.2 0.1 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KXX74543.1 - 6.6e-28 96.3 0.1 1.6e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RFC1 PF08519.7 KXX74543.1 - 0.2 11.3 0.0 1 9.1 0.0 2.1 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain Ribosomal_S17e PF00833.13 KXX74544.1 - 6.6e-58 193.7 0.1 7.7e-58 193.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.3 KXX74545.1 - 9.6e-87 291.1 0.1 1.1e-86 290.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Abhydrolase_1 PF00561.15 KXX74546.1 - 1.6e-44 152.1 0.0 2.8e-43 148.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX74546.1 - 6.2e-14 52.4 1.7 5.3e-13 49.3 1.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX74546.1 - 0.0044 16.7 0.1 0.077 12.7 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KXX74546.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein WSC PF01822.14 KXX74547.1 - 1.9e-12 46.8 4.5 3.8e-12 45.9 3.1 1.5 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.10 KXX74547.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.6 KXX74547.1 - 0.0031 17.0 0.2 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Yip1 PF04893.12 KXX74547.1 - 0.037 13.5 0.2 0.091 12.2 0.0 1.6 2 0 0 2 2 2 0 Yip1 domain VSP PF03302.8 KXX74547.1 - 0.061 11.9 0.2 0.088 11.4 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Hist_deacetyl PF00850.14 KXX74548.1 - 5.7e-61 206.5 0.1 8.3e-61 205.9 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Spo7 PF03907.8 KXX74550.1 - 6.4e-67 225.1 0.0 8.9e-67 224.7 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 KXX74551.1 - 6e-30 104.8 0.2 4.1e-29 102.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX74551.1 - 4.7e-14 52.5 0.0 4e-13 49.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX74551.1 - 1.5e-11 44.2 0.0 4.3e-10 39.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KXX74551.1 - 2.3e-05 23.6 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KXX74551.1 - 0.00015 21.2 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 KXX74551.1 - 0.0015 18.8 0.1 0.0056 16.9 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 KXX74551.1 - 0.012 15.0 0.0 0.26 10.6 0.0 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KXX74551.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 KXX74551.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 KXX74551.1 - 0.069 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KXX74551.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 KXX74551.1 - 0.23 10.8 0.0 0.5 9.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) TGT PF01702.13 KXX74553.1 - 7.2e-87 290.6 0.0 8.9e-87 290.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Dabb PF07876.7 KXX74554.1 - 0.06 13.7 0.0 0.063 13.7 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Methyltransf_2 PF00891.13 KXX74556.1 - 1.8e-31 109.1 0.0 4.2e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KXX74556.1 - 3.5e-06 27.5 0.0 1.4e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74556.1 - 0.0039 16.9 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74556.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HATPase_c PF02518.21 KXX74557.1 - 8.2e-23 80.2 0.0 1.7e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KXX74557.1 - 5.4e-19 68.5 0.0 1.2e-06 28.8 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.5 KXX74557.1 - 1e-10 41.5 0.5 0.1 12.6 0.0 5.7 5 1 1 6 6 6 3 PAS fold PAS_8 PF13188.1 KXX74557.1 - 5.5e-09 35.5 0.0 0.0011 18.6 0.0 4.1 4 0 0 4 4 4 2 PAS domain HisKA PF00512.20 KXX74557.1 - 2.4e-08 33.8 0.1 1.7e-07 31.1 0.0 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 KXX74557.1 - 3.5e-07 30.2 0.0 0.052 13.6 0.0 3.1 2 1 0 2 2 2 2 PAS fold PAS PF00989.19 KXX74557.1 - 8.1e-07 28.8 0.0 0.0054 16.5 0.0 3.9 3 1 0 3 3 3 2 PAS fold GAF_3 PF13492.1 KXX74557.1 - 0.027 14.5 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 0 GAF domain Response_reg PF00072.19 KXX74557.1 - 0.05 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Response regulator receiver domain Response_reg PF00072.19 KXX74558.1 - 6.7e-09 35.7 0.0 7.9e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain G-patch PF01585.18 KXX74559.1 - 3e-11 42.9 1.4 7.1e-11 41.7 0.9 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 KXX74559.1 - 1.5e-09 36.8 0.4 4e-09 35.4 0.3 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KXX74559.1 - 4.9e-08 32.4 0.1 0.00073 19.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX74559.1 - 1.1e-05 25.3 0.0 0.3 11.0 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KXX74559.1 - 0.0019 17.9 4.7 0.0067 16.2 2.0 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KXX74559.1 - 0.0052 16.6 0.0 0.97 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KXX74559.1 - 0.012 14.8 0.3 0.027 13.6 0.2 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region DZR PF12773.2 KXX74559.1 - 1.6 8.6 3.7 1.6 8.6 1.3 2.0 2 0 0 2 2 2 0 Double zinc ribbon Asp PF00026.18 KXX74561.1 - 2.4e-61 207.7 0.2 3.2e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX74561.1 - 3.5e-10 40.0 0.3 4.7e-09 36.3 0.0 2.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KXX74561.1 - 5.5e-06 26.1 0.3 0.0051 16.6 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KXX74561.1 - 9.2e-06 26.0 1.3 0.18 12.2 0.5 3.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KXX74561.1 - 0.00032 20.2 0.0 0.001 18.6 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Hydrolase_6 PF13344.1 KXX74562.1 - 8.5e-18 64.1 0.0 2.1e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX74562.1 - 7.1e-15 54.4 0.1 5.5e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KXX74562.1 - 0.0011 19.2 0.0 0.13 12.4 0.0 3.0 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX74562.1 - 0.027 14.8 0.0 12 6.2 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CAF-1_p150 PF11600.3 KXX74563.1 - 0.45 9.8 18.1 0.62 9.4 0.6 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MoaE PF02391.12 KXX74564.1 - 1.1e-32 112.2 0.1 1.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein OPT PF03169.10 KXX74565.1 - 1e-188 628.7 57.5 1.2e-188 628.5 39.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PALP PF00291.20 KXX74566.1 - 4e-76 256.1 0.7 4.9e-76 255.8 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KXX74566.1 - 3.1e-39 132.4 0.0 9.8e-21 73.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 KXX74567.1 - 1.8e-21 75.6 0.4 3.8e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SprA-related PF12118.3 KXX74567.1 - 0.022 14.1 14.7 0.038 13.3 2.0 2.2 2 0 0 2 2 2 0 SprA-related family Pilt PF15453.1 KXX74567.1 - 0.046 13.4 6.9 0.05 13.2 4.8 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF445 PF04286.7 KXX74567.1 - 0.046 13.2 2.3 0.055 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1777 PF08648.7 KXX74567.1 - 0.066 12.9 9.8 0.11 12.2 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Potyvirid-P3 PF13608.1 KXX74567.1 - 0.14 11.2 4.1 0.18 10.8 2.8 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Neur_chan_memb PF02932.11 KXX74567.1 - 0.18 11.6 1.5 0.26 11.1 1.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UNC-79 PF14776.1 KXX74567.1 - 0.19 10.0 0.6 0.35 9.1 0.1 1.5 1 1 1 2 2 2 0 Cation-channel complex subunit UNC-79 DUF2637 PF10935.3 KXX74567.1 - 0.59 10.0 3.6 0.15 11.9 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) RAB3GAP2_N PF14655.1 KXX74567.1 - 3.3 6.6 5.2 1.3 7.9 0.2 2.3 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SHR3_chaperone PF08229.6 KXX74567.1 - 7.4 5.4 7.4 0.24 10.3 0.3 2.0 2 0 0 2 2 2 0 ER membrane protein SH3 DUF1168 PF06658.7 KXX74567.1 - 8.6 5.8 21.9 18 4.8 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) TLD PF07534.11 KXX74568.1 - 3.5e-30 104.8 0.0 8.8e-30 103.5 0.0 1.7 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 KXX74568.1 - 8.5e-13 48.3 0.3 2.8e-12 46.6 0.2 2.0 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal RPEL PF02755.10 KXX74569.1 - 4.4e-19 67.1 3.0 3.3e-10 38.9 0.1 2.5 3 0 0 3 3 3 2 RPEL repeat FKBP_C PF00254.23 KXX74570.1 - 2.5e-31 107.5 0.0 3.5e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Tannase PF07519.6 KXX74571.1 - 1.5e-20 73.3 0.0 1.6e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase IMS PF00817.15 KXX74572.1 - 1.5e-42 144.8 0.0 3.4e-42 143.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX74572.1 - 1.4e-14 54.1 0.1 3.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KXX74572.1 - 1.4e-05 24.8 0.0 4.6e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif Memo PF01875.12 KXX74573.1 - 4.5e-30 104.4 0.0 6.1e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Tannase PF07519.6 KXX74574.1 - 5.8e-62 209.9 0.2 1.6e-61 208.5 0.1 1.6 1 1 0 1 1 1 1 Tannase and feruloyl esterase NAD_binding_4 PF07993.7 KXX74575.1 - 5.6e-35 120.4 0.0 9.2e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KXX74575.1 - 1.2e-27 96.3 0.0 1.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KXX74575.1 - 8.9e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KXX74575.1 - 8.7e-10 38.7 0.0 3.7e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 KXX74575.1 - 5.9e-06 26.2 0.4 5.9e-06 26.2 0.3 2.7 3 1 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KXX74575.1 - 6e-05 23.1 0.7 0.00048 20.1 0.0 2.7 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KXX74575.1 - 0.00068 19.3 0.3 0.0071 16.0 0.0 2.5 2 1 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 KXX74575.1 - 0.0098 16.1 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KXX74575.1 - 0.098 12.5 0.2 4.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Acyl_transf_1 PF00698.16 KXX74576.1 - 3.2e-63 213.9 0.0 6e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX74576.1 - 2.7e-59 200.7 0.7 4.3e-59 200.1 0.5 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 KXX74576.1 - 4.3e-59 200.0 0.1 1e-58 198.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX74576.1 - 2.2e-56 190.4 0.1 4.4e-56 189.3 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX74576.1 - 1.2e-42 145.7 0.0 3.3e-42 144.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX74576.1 - 6.1e-40 135.7 0.0 1.2e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX74576.1 - 5.1e-19 68.5 0.0 2.2e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74576.1 - 2.4e-11 43.5 0.0 7.3e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74576.1 - 7.2e-10 38.6 0.0 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74576.1 - 3.9e-09 37.0 0.0 1.6e-08 35.1 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KXX74576.1 - 1e-07 31.5 0.0 5.5e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX74576.1 - 2.2e-07 31.0 0.1 5.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KXX74576.1 - 4.5e-07 30.2 0.0 1.5e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74576.1 - 2e-05 24.8 0.0 0.00012 22.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KXX74576.1 - 0.0013 18.2 0.0 0.0045 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KXX74576.1 - 0.0042 16.2 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 KXX74576.1 - 0.019 14.5 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Shikimate_DH PF01488.15 KXX74576.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thiolase_N PF00108.18 KXX74576.1 - 0.32 9.9 0.1 1.2 8.0 0.0 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.7 KXX74576.1 - 0.51 9.3 0.1 2 7.4 0.1 1.9 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein Lipase_GDSL_2 PF13472.1 KXX74577.1 - 1.2e-14 54.7 0.1 1.6e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX74577.1 - 2.1e-11 44.1 0.2 3.3e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA-synt_2c PF01411.14 KXX74577.1 - 0.026 12.8 0.0 0.034 12.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) AMP-binding PF00501.23 KXX74579.1 - 1.6e-105 352.9 0.0 2.9e-105 352.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KXX74579.1 - 2.7e-85 285.9 0.3 2.7e-85 285.9 0.2 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX74579.1 - 3.2e-64 217.2 0.0 5.8e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KXX74579.1 - 2.9e-61 206.2 5.9 2.3e-60 203.3 2.7 3.1 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KXX74579.1 - 4.9e-53 179.4 5.9 1.6e-52 177.8 2.0 3.4 4 0 0 4 4 4 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KXX74579.1 - 1.7e-52 177.8 0.0 1.1e-51 175.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KXX74579.1 - 1.5e-45 153.8 1.7 3.8e-45 152.5 1.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KXX74579.1 - 3.6e-22 78.4 0.0 1.2e-11 44.6 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KXX74579.1 - 6e-13 48.7 0.1 5.3e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 KXX74579.1 - 3.9e-10 40.5 0.0 1.6e-09 38.6 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 KXX74579.1 - 9.5e-06 24.7 0.1 1.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 KXX74579.1 - 0.0001 22.4 0.1 0.091 12.7 0.0 3.7 3 0 0 3 3 3 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX74579.1 - 0.0057 15.5 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NmrA PF05368.8 KXX74579.1 - 0.031 13.5 0.2 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.14 KXX74579.1 - 0.48 9.0 0.1 27 3.3 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KXX74580.1 - 2.5e-15 56.3 0.0 3.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KXX74580.1 - 0.00025 20.7 0.0 0.00067 19.3 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KXX74580.1 - 0.0012 18.9 0.0 0.0037 17.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX74580.1 - 0.017 15.0 0.3 0.049 13.5 0.1 1.9 2 1 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KXX74580.1 - 0.053 12.2 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX74580.1 - 0.1 12.0 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PhyH PF05721.8 KXX74582.1 - 1.3e-36 126.6 0.0 1.7e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KXX74582.1 - 0.15 10.5 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) DJ-1_PfpI PF01965.19 KXX74583.1 - 4.8e-28 97.4 2.6 1.3e-27 96.0 1.8 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KXX74583.1 - 4.1e-19 67.8 0.1 7.9e-19 66.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KXX74583.1 - 0.0079 15.4 0.0 0.032 13.4 0.0 1.9 2 1 0 2 2 2 1 Putative amidotransferase GATase_3 PF07685.9 KXX74583.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DZR PF12773.2 KXX74584.1 - 0.0011 18.7 1.2 0.0024 17.6 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KXX74584.1 - 0.047 12.9 9.4 0.19 10.9 6.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KXX74584.1 - 0.12 11.8 10.1 0.73 9.3 1.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 KXX74584.1 - 0.26 10.8 10.2 7.4 6.2 1.0 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Tic20 PF09685.5 KXX74584.1 - 0.34 10.9 2.6 0.57 10.1 1.8 1.3 1 0 0 1 1 1 0 Tic20-like protein Nudix_N_2 PF14803.1 KXX74584.1 - 0.37 10.5 5.8 4.9 6.9 0.5 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF1469 PF07332.6 KXX74584.1 - 1.5 8.5 5.7 12 5.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF805 PF05656.9 KXX74584.1 - 1.6 8.5 8.3 18 5.2 5.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1218 PF06749.7 KXX74584.1 - 4.2 7.8 7.1 1.6 9.2 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Acyl_transf_3 PF01757.17 KXX74585.1 - 2e-30 105.7 35.5 2.5e-30 105.4 24.6 1.1 1 0 0 1 1 1 1 Acyltransferase family zf-CCHC PF00098.18 KXX74586.1 - 1.9e-06 27.5 5.5 0.00072 19.3 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle DUF3139 PF11337.3 KXX74586.1 - 0.057 13.7 0.4 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) zf-CCHC_2 PF13696.1 KXX74586.1 - 1.1 8.7 7.8 0.37 10.3 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle Gly_transf_sug PF04488.10 KXX74588.1 - 1.1e-09 38.5 0.1 1.1e-09 38.5 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif CAF-1_p150 PF11600.3 KXX74588.1 - 0.0099 15.2 40.8 0.014 14.7 28.3 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acetyltransf_6 PF13480.1 KXX74588.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NARP1 PF12569.3 KXX74588.1 - 0.65 8.6 25.9 0.95 8.1 17.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Atg14 PF10186.4 KXX74588.1 - 0.66 8.8 14.2 0.89 8.4 9.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAGA_bind PF06217.7 KXX74588.1 - 0.73 9.7 17.7 1.1 9.1 12.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 KXX74588.1 - 0.9 9.2 17.3 6.2 6.5 11.5 2.1 2 0 0 2 2 2 0 DDHD domain RR_TM4-6 PF06459.7 KXX74588.1 - 5.5 6.8 25.6 7.8 6.2 17.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2413 PF10310.4 KXX74588.1 - 8 5.1 27.7 12 4.6 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 KXX74588.1 - 9.8 5.4 33.8 16 4.7 23.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ion_trans PF00520.26 KXX74589.1 - 6.4e-07 28.8 15.3 6.4e-07 28.8 10.6 3.1 3 1 0 3 3 3 1 Ion transport protein PKD_channel PF08016.7 KXX74589.1 - 8.9e-05 21.0 11.8 0.00073 18.0 0.7 2.2 1 1 1 2 2 2 2 Polycystin cation channel zf-C2H2_4 PF13894.1 KXX74590.1 - 0.017 15.4 11.6 0.31 11.4 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX74590.1 - 0.44 10.9 5.7 0.26 11.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Cellulase PF00150.13 KXX74592.1 - 1e-24 87.2 1.7 2.3e-24 86.0 0.1 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL PF00657.17 KXX74592.1 - 1.7e-19 70.5 0.0 9e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KXX74592.1 - 6.6e-19 68.7 0.3 5.9e-18 65.6 0.1 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Cellulase-like PF12876.2 KXX74592.1 - 1.3e-05 25.5 0.0 8.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KXX74592.1 - 0.0011 17.9 0.0 0.0032 16.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KXX74592.1 - 0.01 14.9 0.1 0.045 12.8 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase Toxin_43 PF15604.1 KXX74593.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 43 Fungal_trans PF04082.13 KXX74594.1 - 1.1e-36 126.0 0.0 1.6e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74594.1 - 4.1e-07 29.7 10.5 7.3e-07 28.9 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLRV_ORF5 PF01690.12 KXX74594.1 - 2.2 7.3 11.2 3.5 6.6 7.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WSC PF01822.14 KXX74595.1 - 1.4e-75 249.2 67.6 2.8e-20 72.0 7.6 4.9 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.18 KXX74595.1 - 1e-23 84.0 0.1 2.3e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.20 KXX74596.1 - 4.5e-33 113.8 0.0 6.3e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KXX74596.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GAS2 PF02187.12 KXX74597.1 - 4.2e-05 23.2 0.0 9.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain RWD PF05773.17 KXX74598.1 - 5e-23 81.1 0.0 8.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KXX74598.1 - 2e-20 72.3 38.3 3.9e-15 55.4 2.7 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KXX74598.1 - 0.00011 21.9 10.0 0.00011 21.9 7.0 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX74598.1 - 0.0015 18.5 11.1 0.0015 18.5 7.7 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX74598.1 - 0.0048 16.5 9.8 0.0048 16.5 6.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX74598.1 - 0.0063 16.2 5.3 0.0063 16.2 3.6 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KXX74598.1 - 0.0065 16.1 10.2 0.0065 16.1 7.1 3.9 2 1 1 3 3 3 1 zinc-RING finger domain PAP2 PF01569.16 KXX74599.1 - 5.1e-18 64.9 0.8 9.9e-18 64.0 0.5 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KXX74599.1 - 0.087 12.5 3.0 0.89 9.2 0.0 2.7 2 1 0 2 2 2 0 Divergent PAP2 family MARVEL PF01284.18 KXX74600.1 - 0.4 10.5 19.1 0.82 9.4 13.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain EphA2_TM PF14575.1 KXX74600.1 - 2.1 8.7 0.0 2.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SURF6 PF04935.7 KXX74601.1 - 7.3e-47 159.4 43.8 7.3e-47 159.4 30.3 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KXX74601.1 - 1.2e-20 73.3 2.1 1.2e-20 73.3 1.5 6.6 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 XPG_I PF00867.13 KXX74602.1 - 9.5e-25 86.4 0.0 2.1e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KXX74602.1 - 1.5e-20 73.3 0.0 2.8e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KXX74602.1 - 0.00044 19.8 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KXX74602.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold NP1-WLL PF11733.3 KXX74602.1 - 0.061 13.5 0.5 0.061 13.5 0.3 2.9 2 1 1 3 3 3 0 Non-capsid protein NP1 Methyltransf_2 PF00891.13 KXX74603.1 - 7.9e-24 84.1 0.0 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KXX74603.1 - 0.00012 22.6 0.0 0.00087 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain GPP34 PF05719.6 KXX74604.1 - 4.4e-65 219.6 0.1 5.8e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) LCCL PF03815.14 KXX74605.1 - 7.7e-23 80.3 0.0 1.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF4243 PF14027.1 KXX74606.1 - 5.7e-33 114.7 0.0 7.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pyridoxal_deC PF00282.14 KXX74607.1 - 5.9e-72 242.1 0.0 5.2e-71 239.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KXX74607.1 - 0.00088 18.5 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KXX74607.1 - 0.011 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DC_STAMP PF07782.8 KXX74608.1 - 0.29 10.7 2.1 0.86 9.1 0.1 2.0 1 1 1 2 2 2 0 DC-STAMP-like protein HNH PF01844.18 KXX74609.1 - 9.7e-05 22.1 0.5 0.00019 21.2 0.3 1.5 1 1 0 1 1 1 1 HNH endonuclease Thi4 PF01946.12 KXX74610.1 - 7.5e-102 339.2 0.0 9e-102 339.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KXX74610.1 - 1.4e-09 37.3 0.5 7.5e-08 31.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX74610.1 - 6.6e-06 25.2 0.4 1.9e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX74610.1 - 9.2e-06 25.5 0.2 2.4e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX74610.1 - 1.5e-05 24.0 1.1 0.0008 18.3 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KXX74610.1 - 9.9e-05 22.1 0.7 0.00051 19.8 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX74610.1 - 0.00029 20.8 0.1 0.00044 20.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX74610.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KXX74610.1 - 0.0071 15.4 0.3 0.017 14.1 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX74610.1 - 0.0096 14.4 0.2 0.015 13.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KXX74610.1 - 0.037 14.4 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX74610.1 - 0.059 12.2 0.1 0.18 10.6 0.0 1.7 2 1 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.10 KXX74610.1 - 0.07 11.2 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) AMMECR1 PF01871.12 KXX74612.1 - 2.1e-46 157.1 0.0 4.1e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 AMMECR1 DUF1897 PF09005.5 KXX74612.1 - 0.02 14.3 0.3 0.039 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Ras PF00071.17 KXX74613.1 - 1.4e-38 131.8 0.0 5.6e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KXX74613.1 - 3e-11 43.8 0.0 6.7e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KXX74613.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 KXX74613.1 - 0.023 13.9 0.0 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 KXX74613.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.7 KXX74613.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KXX74613.1 - 0.11 11.8 0.0 2.4 7.5 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2962 PF11176.3 KXX74614.1 - 5.6e-42 142.9 7.5 6.4e-42 142.7 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 KXX74614.1 - 0.0024 18.6 3.7 0.43 11.4 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain RRP7 PF12923.2 KXX74614.1 - 2.3 8.2 12.0 0.37 10.7 0.5 2.4 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) MAM33 PF02330.11 KXX74615.1 - 7e-32 110.8 0.1 1.6e-31 109.6 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein Polysacc_synt_4 PF04669.8 KXX74616.1 - 1.1e-18 67.3 0.6 9e-15 54.5 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Phageshock_PspG PF09583.5 KXX74617.1 - 0.016 15.2 0.6 0.016 15.2 0.4 3.4 5 0 0 5 5 5 0 Phage shock protein G (Phageshock_PspG) PQQ_3 PF13570.1 KXX74619.1 - 0.001 19.2 2.6 4.6 7.6 0.0 4.4 4 0 0 4 4 4 2 PQQ-like domain ABC_tran PF00005.22 KXX74620.1 - 2e-55 186.8 0.0 1.5e-26 93.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX74620.1 - 4.5e-54 183.7 31.8 1.1e-29 103.7 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KXX74620.1 - 5.5e-17 62.6 0.0 2.8e-05 24.2 0.0 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KXX74620.1 - 3.6e-15 55.7 0.0 7.4e-06 25.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KXX74620.1 - 9.7e-09 35.4 0.0 0.013 15.5 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KXX74620.1 - 4.6e-08 33.2 0.0 0.0037 17.2 0.0 3.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KXX74620.1 - 2.2e-07 30.3 2.4 0.0081 15.6 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KXX74620.1 - 5.8e-07 29.1 0.1 0.16 11.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KXX74620.1 - 8.5e-07 29.8 0.0 0.032 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KXX74620.1 - 8.4e-06 25.4 0.8 0.11 11.8 0.1 3.7 4 0 0 4 4 4 1 AAA-like domain DUF258 PF03193.11 KXX74620.1 - 5.8e-05 22.3 0.1 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX74620.1 - 0.00016 22.0 0.1 0.78 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KXX74620.1 - 0.00036 20.8 0.0 0.76 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KXX74620.1 - 0.0019 16.8 0.1 0.051 12.1 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 KXX74620.1 - 0.0021 17.9 0.1 3.3 7.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KXX74620.1 - 0.0061 16.2 0.3 2.4 7.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KXX74620.1 - 0.0095 15.8 0.0 1.6 8.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KXX74620.1 - 0.0098 15.8 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 KXX74620.1 - 0.0098 15.7 1.9 0.69 9.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KXX74620.1 - 0.028 14.1 0.3 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 KXX74620.1 - 0.035 12.6 0.0 4 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 KXX74620.1 - 0.047 13.8 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KXX74620.1 - 0.052 13.2 0.1 31 4.1 0.0 3.2 3 0 0 3 3 3 0 Adenylylsulphate kinase Miro PF08477.8 KXX74620.1 - 0.055 13.9 0.1 12 6.3 0.0 3.1 4 0 0 4 4 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KXX74620.1 - 0.055 12.9 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KXX74620.1 - 0.081 13.1 0.0 66 3.7 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KXX74620.1 - 0.091 11.5 0.1 5.6 5.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 KXX74620.1 - 0.11 12.1 0.2 20 4.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 KXX74620.1 - 0.15 11.9 0.0 3.4 7.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 KXX74620.1 - 0.4 9.7 1.1 37 3.3 0.0 3.2 4 0 0 4 4 3 0 Zeta toxin AAA_13 PF13166.1 KXX74620.1 - 0.65 8.3 0.0 36 2.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 KXX74620.1 - 4.3 6.3 4.3 28 3.7 0.0 2.9 4 0 0 4 4 3 0 KaiC HET PF06985.6 KXX74622.1 - 2e-17 63.6 0.0 3.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 KXX74623.1 - 4.3e-47 160.7 0.1 4.9e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 mRNA_triPase PF02940.10 KXX74624.1 - 5.2e-45 153.8 0.0 1.9e-44 151.9 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain DUF1769 PF08588.5 KXX74625.1 - 6.4e-30 102.8 0.3 1.2e-29 101.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MFS_1 PF07690.11 KXX74626.1 - 2.1e-29 102.3 30.7 2.3e-26 92.3 10.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74626.1 - 3.2e-10 39.1 4.4 3.2e-10 39.1 3.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF463 PF04317.7 KXX74627.1 - 0.0089 14.6 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 PC_rep PF01851.17 KXX74628.1 - 3.4e-40 134.0 15.1 5.2e-08 32.6 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KXX74628.1 - 1.2e-18 67.2 0.1 2.3e-12 46.9 0.0 5.0 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 KXX74628.1 - 2e-09 36.7 0.4 0.75 10.0 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KXX74628.1 - 2e-07 31.2 3.1 0.00016 22.0 0.0 5.1 4 2 0 4 4 4 1 HEAT-like repeat adh_short PF00106.20 KXX74629.1 - 3.8e-24 85.4 1.7 4.8e-24 85.1 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX74629.1 - 3.7e-16 59.6 0.0 4.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX74629.1 - 3.6e-08 33.2 0.6 5.2e-08 32.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX74629.1 - 0.027 14.2 0.3 0.058 13.1 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KXX74629.1 - 0.12 11.4 0.1 0.51 9.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HET PF06985.6 KXX74630.1 - 2.8e-34 118.2 0.2 7e-34 116.9 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_M23 PF01551.17 KXX74630.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 ADP_PFK_GK PF04587.10 KXX74630.1 - 0.15 10.2 0.1 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region MR_MLE_C PF13378.1 KXX74631.1 - 9.1e-22 77.1 0.0 2.8e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KXX74631.1 - 3e-13 50.0 0.0 8.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KXX74631.1 - 3.7e-10 39.8 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 KXX74631.1 - 0.16 11.0 0.0 0.56 9.2 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase DUF3431 PF11913.3 KXX74632.1 - 5.4e-90 300.7 0.0 5.4e-90 300.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) Prenyltransf PF01255.14 KXX74632.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Methyltransf_18 PF12847.2 KXX74633.1 - 1.2e-08 35.5 0.1 1.9e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74633.1 - 4.5e-08 32.8 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74633.1 - 6.9e-08 32.8 0.1 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74633.1 - 1.5e-06 28.0 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX74633.1 - 3.9e-06 26.8 0.2 6.5e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KXX74633.1 - 4.4e-05 23.4 0.1 8.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX74633.1 - 0.0017 18.0 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 KR domain MTS PF05175.9 KXX74633.1 - 0.0026 17.1 0.0 0.0058 16.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KXX74633.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KXX74633.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KXX74633.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Tyrosinase PF00264.15 KXX74634.1 - 5.8e-45 154.1 0.0 1.4e-44 152.8 0.0 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 KXX74635.1 - 4.1e-24 84.8 0.1 6e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74635.1 - 1.5e-07 31.2 11.6 2.5e-07 30.4 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 KXX74635.1 - 0.55 9.9 3.0 1.3 8.6 2.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HLH PF00010.21 KXX74636.1 - 3.9e-07 29.6 0.0 4.5e-06 26.2 0.0 2.4 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Abhydrolase_4 PF08386.5 KXX74637.1 - 1.8e-10 40.5 0.1 5.9e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX74637.1 - 2.4e-09 37.1 0.0 4.4e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX74637.1 - 0.00011 22.2 0.1 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SKG6 PF08693.5 KXX74638.1 - 0.063 12.6 0.9 0.13 11.5 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2681 PF10883.3 KXX74638.1 - 0.083 13.1 0.3 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) HemX PF04375.9 KXX74638.1 - 0.14 10.7 4.5 0.19 10.2 3.1 1.1 1 0 0 1 1 1 0 HemX Tropomyosin_1 PF12718.2 KXX74639.1 - 0.00058 19.7 23.4 0.00058 19.7 16.2 2.8 1 1 1 2 2 2 2 Tropomyosin like HR1 PF02185.11 KXX74639.1 - 0.001 18.7 11.9 0.16 11.7 0.1 4.0 3 1 1 4 4 4 2 Hr1 repeat IncA PF04156.9 KXX74639.1 - 0.0044 16.6 11.8 0.0044 16.6 8.2 2.9 1 1 2 3 3 3 1 IncA protein HAP1_N PF04849.8 KXX74639.1 - 0.012 14.6 0.7 0.012 14.6 0.5 3.1 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Menin PF05053.8 KXX74639.1 - 0.37 8.9 5.1 0.64 8.1 3.5 1.3 1 0 0 1 1 1 0 Menin DUF2229 PF09989.4 KXX74639.1 - 0.98 8.8 2.8 1.8 7.9 1.9 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Laminin_II PF06009.7 KXX74639.1 - 1.5 8.6 10.4 4.1 7.1 1.7 3.3 2 1 1 3 3 3 0 Laminin Domain II GAS PF13851.1 KXX74639.1 - 4 6.5 20.9 0.55 9.3 10.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 KXX74639.1 - 5 7.4 24.0 0.13 12.5 2.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF2293 PF10056.4 KXX74642.1 - 8.3e-32 109.0 0.4 8.3e-32 109.0 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) PROCN PF08083.6 KXX74643.1 - 3.7e-220 730.4 10.4 6.2e-220 729.7 7.2 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KXX74643.1 - 2.7e-125 416.2 1.6 4.5e-125 415.5 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KXX74643.1 - 1.7e-93 310.2 1.0 4.9e-93 308.7 0.7 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KXX74643.1 - 1.4e-76 255.3 4.2 1.6e-76 255.1 1.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KXX74643.1 - 1e-66 222.6 0.1 2.2e-66 221.5 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KXX74643.1 - 7.1e-45 151.7 0.4 1.8e-44 150.4 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 KXX74643.1 - 8.3e-44 147.3 0.1 2.2e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 KXX74643.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Ribosomal_S11 PF00411.14 KXX74644.1 - 1.1e-40 138.2 0.4 1.3e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KXX74644.1 - 0.058 12.2 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) eIF-3c_N PF05470.7 KXX74645.1 - 3e-176 587.0 22.1 3e-176 587.0 15.3 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KXX74645.1 - 6.2e-15 55.4 0.2 1.2e-13 51.2 0.0 2.7 2 0 0 2 2 2 1 PCI domain Ribosomal_L30_N PF08079.7 KXX74646.1 - 1.9e-26 91.8 19.8 3e-26 91.2 13.7 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KXX74646.1 - 2.9e-19 68.4 2.8 2.9e-19 68.3 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF3722 PF12519.3 KXX74647.1 - 3.5e-87 291.9 0.0 4.4e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KXX74647.1 - 0.00012 21.4 0.1 0.0023 17.2 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic porin Fe-S_biosyn PF01521.15 KXX74648.1 - 1.5e-11 44.2 0.0 4.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Scytalone_dh PF02982.9 KXX74649.1 - 3.9e-92 306.0 1.0 4.5e-92 305.8 0.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KXX74649.1 - 1.2e-06 28.4 0.2 1.6e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ank_5 PF13857.1 KXX74650.1 - 2.5e-10 40.2 0.0 1.2e-08 34.9 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KXX74650.1 - 6.7e-09 35.1 0.1 5e-07 29.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KXX74650.1 - 1.4e-08 34.9 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX74650.1 - 8.9e-06 26.0 0.0 2.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74650.1 - 0.00035 20.5 0.1 0.0069 16.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DYW_deaminase PF14432.1 KXX74650.1 - 0.007 16.3 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases Ribosomal_S19e PF01090.14 KXX74651.1 - 1.1e-57 193.3 0.8 1.3e-57 193.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 KXX74651.1 - 0.027 14.4 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DUF2802 PF10975.3 KXX74652.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) CobT PF06213.7 KXX74653.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.3 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ricin_B_lectin PF00652.17 KXX74655.1 - 3.2e-17 62.6 1.0 2.8e-07 30.6 0.1 3.9 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KXX74655.1 - 0.00036 20.8 0.0 1.7 9.0 0.0 4.2 4 1 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KXX74655.1 - 0.12 11.6 0.5 1.5 8.1 0.1 2.9 2 1 2 4 4 4 0 Cytolethal distending toxin A/C family zf-C2H2_4 PF13894.1 KXX74658.1 - 0.013 15.7 2.8 3.9 8.0 0.0 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger DUF4066 PF13278.1 KXX74660.1 - 1.6e-22 79.5 0.0 2e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX74660.1 - 4.3e-12 45.7 0.0 5.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.17 KXX74662.1 - 3.8e-54 183.9 0.0 5e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ArsB PF02040.10 KXX74663.1 - 5.2e-16 58.6 20.5 1.3e-10 40.8 5.7 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein Asp PF00026.18 KXX74664.1 - 1.7e-59 201.6 0.0 2.2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX74664.1 - 6.1e-09 36.0 0.0 5.2e-07 29.7 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KXX74664.1 - 8.2e-06 25.4 0.4 0.0043 16.6 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KXX74664.1 - 0.012 16.1 0.3 30 5.1 0.0 3.5 3 0 0 3 3 3 0 Aspartyl protease DUF2235 PF09994.4 KXX74665.1 - 2.8e-54 184.3 0.0 3.7e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) EMG1 PF03587.9 KXX74666.1 - 3.6e-77 258.2 0.0 4.2e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase 2-oxoacid_dh PF00198.18 KXX74667.1 - 5.8e-81 271.1 0.1 7.4e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KXX74667.1 - 4.5e-18 64.6 1.1 1e-17 63.5 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KXX74667.1 - 0.00095 18.7 0.3 0.52 10.0 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 KXX74667.1 - 0.028 14.7 0.1 0.71 10.2 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.3 KXX74667.1 - 0.078 13.2 1.4 0.46 10.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) DUF2360 PF10152.4 KXX74667.1 - 1.3 9.3 9.2 2.4 8.4 6.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) AA_permease PF00324.16 KXX74668.1 - 5e-60 203.1 32.6 1.5e-59 201.6 22.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX74668.1 - 5.2e-27 94.4 29.2 8e-27 93.8 20.3 1.2 1 0 0 1 1 1 1 Amino acid permease Histone PF00125.19 KXX74669.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX74669.1 - 1.3e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX74670.1 - 9.5e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX74670.1 - 4.2e-05 23.5 0.0 9.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KXX74670.1 - 0.00021 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KXX74670.1 - 0.007 15.0 1.5 0.0087 14.7 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KXX74670.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KXX74670.1 - 0.029 14.8 0.4 0.039 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Glyco_hydro_53 PF07745.8 KXX74670.1 - 0.064 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 R3H PF01424.17 KXX74671.1 - 3.3e-12 45.9 0.0 8.3e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KXX74671.1 - 9.5e-11 41.3 1.4 2e-10 40.2 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KXX74671.1 - 0.014 15.2 0.4 0.054 13.3 0.3 2.1 1 0 0 1 1 1 0 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 KXX74672.1 - 1.4e-95 319.6 0.0 1.7e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 KXX74673.1 - 3.7e-24 84.2 0.4 3.7e-24 84.2 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 KXX74673.1 - 1.6e-10 40.7 9.9 4.5e-09 36.2 1.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX74673.1 - 2.1e-10 40.4 10.3 2.2e-10 40.3 2.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KXX74673.1 - 1.1e-07 31.9 7.7 0.00032 20.7 1.6 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KXX74673.1 - 1.6e-05 24.9 9.4 0.027 14.8 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KXX74673.1 - 0.00014 21.6 9.0 0.025 14.4 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KXX74673.1 - 0.00046 20.3 4.6 0.18 12.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 KXX74673.1 - 0.011 15.0 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.1 KXX74673.1 - 0.021 15.1 1.7 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF2256 PF10013.4 KXX74673.1 - 0.076 12.7 3.8 13 5.6 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2387 PF09526.5 KXX74673.1 - 0.089 12.7 6.0 0.059 13.2 2.3 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) SPX PF03105.14 KXX74674.1 - 3.1e-30 105.8 0.0 4.2e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 KXX74674.1 - 8.5e-06 25.3 13.8 1.6e-05 24.4 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX74674.1 - 6.9e-05 22.6 13.1 0.00013 21.8 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KXX74674.1 - 8.3e-05 22.1 10.9 0.00013 21.5 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX74674.1 - 9.5e-05 22.1 14.0 0.00018 21.2 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX74674.1 - 0.0015 18.2 11.3 0.0029 17.3 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX74674.1 - 0.0047 16.9 15.2 0.0091 16.0 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KXX74674.1 - 0.056 13.0 5.2 0.13 11.8 3.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KXX74674.1 - 2.5 7.9 6.1 4.9 7.0 4.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.1 KXX74674.1 - 3 7.6 9.7 7 6.4 6.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Cys_Met_Meta_PP PF01053.15 KXX74675.1 - 2.6e-33 114.8 0.0 3.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Gly-zipper_OmpA PF13436.1 KXX74676.1 - 0.12 12.0 1.1 0.25 11.0 0.8 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Complex1_LYR PF05347.10 KXX74677.1 - 2.4e-10 40.0 2.9 3.4e-10 39.5 2.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX74677.1 - 4e-08 33.3 1.5 6.2e-08 32.7 1.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like TFR_dimer PF04253.10 KXX74679.1 - 1.5e-21 76.2 0.0 2.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KXX74679.1 - 4.1e-14 52.7 0.0 9.8e-14 51.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KXX74679.1 - 2.1e-08 33.7 0.0 5.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 PA domain BLOC1_2 PF10046.4 KXX74679.1 - 0.054 13.6 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nicastrin PF05450.10 KXX74679.1 - 0.078 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Nicastrin RasGAP_C PF03836.10 KXX74680.1 - 9.3e-49 164.7 3.1 3e-48 163.1 2.2 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KXX74680.1 - 2.3e-42 144.8 0.0 6.3e-42 143.4 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KXX74680.1 - 4e-17 60.1 35.3 0.043 13.4 0.5 13.5 14 0 0 14 14 14 7 IQ calmodulin-binding motif CH PF00307.26 KXX74680.1 - 6.9e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Sec7 PF01369.15 KXX74681.1 - 7.3e-43 146.4 0.0 1.4e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KXX74681.1 - 8.3e-19 67.9 0.0 1.8e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Cse1 PF08506.5 KXX74681.1 - 1 7.8 0.1 1.8 7.0 0.1 1.3 1 0 0 1 1 1 0 Cse1 DUF3728 PF12528.3 KXX74682.1 - 0.02 15.2 0.4 0.033 14.5 0.3 1.3 1 0 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) DUF1510 PF07423.6 KXX74682.1 - 8.4 5.6 10.2 11 5.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) IMPDH PF00478.20 KXX74683.1 - 8.5e-133 442.5 1.7 1e-132 442.3 1.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KXX74683.1 - 1.5e-17 63.0 0.0 1.4e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KXX74683.1 - 6.7e-10 38.3 1.6 5.4e-08 32.0 0.6 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 KXX74683.1 - 1e-08 34.7 4.6 0.00074 18.7 3.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KXX74683.1 - 0.00025 20.3 2.6 0.008 15.4 0.3 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 KXX74683.1 - 0.081 11.9 2.0 0.1 11.6 0.5 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG AlaDh_PNT_N PF05222.10 KXX74684.1 - 7.1e-26 90.8 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KXX74684.1 - 9.3e-17 61.0 0.1 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RP-C_C PF11800.3 KXX74685.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4355 PF14265.1 KXX74685.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MFS_1 PF07690.11 KXX74686.1 - 3.5e-33 114.7 36.5 3.5e-23 81.8 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74686.1 - 3.1e-10 39.2 6.0 3.1e-10 39.2 4.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KXX74686.1 - 1.5e-06 26.8 21.8 0.00023 19.6 2.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KXX74686.1 - 0.014 13.5 0.6 0.023 12.8 0.4 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Microtub_assoc PF07989.6 KXX74687.1 - 1e-19 70.1 8.1 1e-19 70.1 5.6 8.5 6 2 4 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 KXX74687.1 - 5.2e-10 39.2 11.9 5.2e-10 39.2 8.2 11.8 12 1 1 13 13 13 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KXX74687.1 - 0.00072 18.8 1.1 0.00072 18.8 0.8 5.9 4 2 1 6 6 6 3 Reovirus sigma C capsid protein COG5 PF10392.4 KXX74687.1 - 0.00081 19.3 1.8 0.00081 19.3 1.2 8.0 6 4 2 8 8 8 1 Golgi transport complex subunit 5 HALZ PF02183.13 KXX74687.1 - 0.039 13.6 0.4 0.039 13.6 0.3 10.8 10 1 1 11 11 11 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 KXX74687.1 - 0.068 13.4 0.0 0.068 13.4 0.0 7.2 7 2 1 8 8 8 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KXX74687.1 - 0.25 11.1 40.3 0.72 9.6 2.0 6.7 4 1 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KXX74687.1 - 3.2 7.8 58.3 0.097 12.7 4.3 6.9 4 2 2 6 6 6 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KXX74687.1 - 9.9 5.9 0.0 5.2 6.8 10.2 9.6 5 4 3 8 8 8 0 TPR/MLP1/MLP2-like protein Terpene_synth_C PF03936.11 KXX74688.1 - 1.5e-06 27.6 0.0 1.5e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Matrilin_ccoil PF10393.4 KXX74688.1 - 0.17 11.2 0.9 2.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3366 PF11846.3 KXX74690.1 - 3.8 7.3 7.2 0.14 12.0 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) 2OG-FeII_Oxy PF03171.15 KXX74692.1 - 3.5e-13 49.6 0.1 5.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KXX74692.1 - 4.5e-09 36.8 0.0 8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Amidohydro_4 PF13147.1 KXX74693.1 - 8.4e-10 39.1 0.3 8.4e-10 39.1 0.2 4.4 3 2 1 4 4 4 2 Amidohydrolase Amidohydro_5 PF13594.1 KXX74693.1 - 1.5e-06 27.8 2.4 1.8e-05 24.4 0.2 3.3 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX74693.1 - 2.4e-05 24.1 0.2 0.00035 20.3 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family UPF0444 PF15475.1 KXX74695.1 - 0.062 13.3 0.6 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Fungal_trans PF04082.13 KXX74696.1 - 8.1e-05 21.6 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KXX74697.1 - 1.2e-71 241.5 0.0 1.7e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KXX74698.1 - 1.1e-17 64.1 0.0 1.8e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74698.1 - 1.1e-09 38.8 0.0 5.2e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74698.1 - 4.4e-08 33.5 0.0 1.6e-07 31.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74698.1 - 3.8e-05 23.3 0.0 0.00022 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74698.1 - 4.5e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74698.1 - 0.00052 20.3 0.0 0.007 16.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX74698.1 - 0.00087 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KXX74698.1 - 0.0023 17.1 0.0 0.026 13.6 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX74698.1 - 0.0079 16.2 0.0 0.056 13.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KXX74698.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 KXX74698.1 - 0.07 12.5 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PLA2G12 PF06951.6 KXX74699.1 - 0.0013 18.3 7.6 0.002 17.7 5.3 1.3 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) PIP49_C PF12260.3 KXX74699.1 - 0.012 14.9 1.5 0.022 14.1 1.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FAD_binding_3 PF01494.14 KXX74700.1 - 2.4e-16 59.7 4.2 1.8e-15 56.8 2.9 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX74700.1 - 1e-15 57.5 0.4 1.6e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX74700.1 - 1.5e-07 31.7 0.3 0.00044 20.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX74700.1 - 5.3e-05 23.1 0.5 0.00034 20.5 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KXX74700.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KXX74700.1 - 0.049 13.6 0.4 0.57 10.1 0.1 2.3 3 0 0 3 3 3 0 NADH(P)-binding Trp_halogenase PF04820.9 KXX74700.1 - 0.054 12.1 2.0 0.98 7.9 0.0 2.2 1 1 1 2 2 2 0 Tryptophan halogenase p450 PF00067.17 KXX74701.1 - 1e-46 159.4 0.0 1.6e-41 142.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3649 PF12365.3 KXX74701.1 - 0.22 11.0 1.5 0.59 9.6 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) CorA PF01544.13 KXX74702.1 - 2.6e-12 46.3 3.9 7e-12 44.9 2.7 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KXX74702.1 - 0.00028 20.2 1.0 0.00049 19.4 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Ni_hydr_CYTB PF01292.15 KXX74702.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Surp PF01805.15 KXX74703.1 - 3.4e-17 61.8 0.0 6.3e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Surp module DAO PF01266.19 KXX74704.1 - 5.8e-49 166.8 0.7 8.2e-49 166.3 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX74704.1 - 1.5e-06 28.0 0.1 0.00096 18.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KXX74704.1 - 0.0004 20.3 0.0 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KXX74704.1 - 0.0004 19.3 0.0 0.0022 16.9 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KXX74704.1 - 0.0013 17.4 0.0 0.25 9.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 KXX74704.1 - 0.0031 17.8 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX74704.1 - 0.009 15.0 2.5 0.64 8.9 0.0 2.8 4 0 0 4 4 4 2 FAD binding domain FAD_binding_2 PF00890.19 KXX74704.1 - 0.012 14.5 0.0 3.6 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KXX74704.1 - 0.018 14.8 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 KXX74704.1 - 0.075 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 KXX74704.1 - 0.11 11.4 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ETF_QO PF05187.8 KXX74705.1 - 1.4e-44 150.5 0.0 2.4e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KXX74705.1 - 6.5e-08 31.8 1.0 0.00021 20.2 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX74705.1 - 7e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KXX74705.1 - 1.3e-05 24.5 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX74705.1 - 8.9e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX74705.1 - 9.4e-05 21.4 0.4 0.002 17.0 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KXX74705.1 - 0.00016 20.2 0.4 0.00023 19.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KXX74705.1 - 0.00077 18.1 0.0 0.14 10.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX74705.1 - 0.00097 18.9 0.1 0.0034 17.1 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KXX74705.1 - 0.0011 18.1 0.0 0.0067 15.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KXX74705.1 - 0.0012 18.0 0.1 0.0021 17.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 KXX74705.1 - 0.0025 18.1 1.1 0.0074 16.6 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.22 KXX74705.1 - 0.0044 17.3 0.2 5 7.6 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX74705.1 - 0.0099 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX74705.1 - 0.015 14.2 0.2 0.025 13.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KXX74705.1 - 0.074 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF605 PF04652.11 KXX74706.1 - 4.1 6.7 9.1 5.2 6.3 6.3 1.1 1 0 0 1 1 1 0 Vta1 like TBP PF00352.16 KXX74707.1 - 2.3e-70 232.0 0.2 3.3e-35 119.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KXX74707.1 - 0.0002 21.3 0.0 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Methyltransf_16 PF10294.4 KXX74710.1 - 1.4e-08 34.4 0.0 4.4e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KXX74710.1 - 0.00035 21.1 0.0 0.0009 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KXX74710.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KXX74710.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SNF2_N PF00176.18 KXX74711.1 - 2.3e-76 256.4 0.1 7.3e-75 251.5 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX74711.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 KXX74711.1 - 0.0097 15.3 1.4 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 DEAD_2 AA_permease_2 PF13520.1 KXX74712.1 - 3.7e-24 85.0 8.0 4.5e-24 84.7 5.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX74712.1 - 6.2e-09 34.7 5.6 8e-09 34.3 3.9 1.1 1 0 0 1 1 1 1 Amino acid permease EcsB PF05975.7 KXX74713.1 - 0.019 13.4 0.3 0.026 12.9 0.2 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Esterase PF00756.15 KXX74714.1 - 3.3e-08 33.2 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KXX74714.1 - 0.00014 21.7 0.1 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX74714.1 - 0.00019 20.7 0.1 0.00033 19.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PNP_UDP_1 PF01048.15 KXX74715.1 - 1.5e-14 53.5 2.2 8.5e-14 51.0 1.6 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KXX74716.1 - 6.1e-10 38.9 0.0 2.2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Ank PF00023.25 KXX74716.1 - 1.4e-07 30.9 0.1 4.9e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KXX74716.1 - 4.5e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX74716.1 - 0.00018 21.9 0.0 0.00055 20.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 KXX74716.1 - 0.00028 20.9 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX74716.1 - 0.0014 18.7 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KXX74716.1 - 0.016 14.6 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KXX74716.1 - 0.017 15.3 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KXX74716.1 - 0.02 13.7 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KXX74716.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KXX74716.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 NTPase Ank_5 PF13857.1 KXX74716.1 - 0.05 13.8 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 1 0 Ankyrin repeats (many copies) AAA_19 PF13245.1 KXX74716.1 - 0.08 12.7 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 KXX74716.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KXX74716.1 - 0.12 13.1 0.0 0.78 10.5 0.0 2.5 3 1 0 3 3 2 0 AAA domain KAP_NTPase PF07693.9 KXX74716.1 - 0.23 10.4 0.6 16 4.3 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Transpep_BrtH PF14399.1 KXX74717.1 - 4.5e-24 85.3 0.0 5.2e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase Peptidase_C39 PF03412.10 KXX74717.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Tyrosinase PF00264.15 KXX74718.1 - 2.4e-55 188.1 0.7 2.4e-55 188.1 0.5 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase WBS_methylT PF12589.3 KXX74719.1 - 9.5e-17 61.2 6.7 1.7e-16 60.4 4.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KXX74719.1 - 1.1e-10 41.8 0.0 2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74719.1 - 1.3e-07 31.8 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74719.1 - 4.6e-06 26.2 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74719.1 - 8.4e-05 22.3 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KXX74719.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KXX74719.1 - 0.00019 21.8 0.0 0.00057 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74719.1 - 0.00031 21.3 0.0 0.00064 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX74719.1 - 0.0022 17.1 0.0 0.023 13.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KXX74719.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX74719.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.14 KXX74720.1 - 2.7e-16 58.9 0.0 2.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KXX74720.1 - 5e-12 46.3 0.0 9.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX74720.1 - 2.7e-09 36.8 0.8 2e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX74720.1 - 2.9e-08 33.6 0.2 2.1e-07 30.8 0.0 2.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX74720.1 - 9.7e-07 28.0 0.0 3.7e-05 22.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KXX74720.1 - 3.8e-06 26.9 0.0 9.1e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX74720.1 - 0.0022 18.3 0.3 3.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX74720.1 - 0.003 16.5 0.0 0.0073 15.2 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX74720.1 - 0.0089 14.5 0.0 0.015 13.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KXX74720.1 - 0.045 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KXX74720.1 - 0.064 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 7tm_2 PF00002.19 KXX74721.1 - 7.8e-12 44.7 9.4 7.8e-12 44.7 6.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KXX74721.1 - 1.8e-08 33.6 7.7 3.9e-08 32.5 5.4 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KXX74721.1 - 8e-07 28.8 12.4 1.6e-06 27.8 8.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 TMEM190 PF15431.1 KXX74721.1 - 0.2 11.6 3.1 0.5 10.2 0.7 2.5 2 1 1 3 3 3 0 Transmembrane protein 190 FixQ PF05545.6 KXX74721.1 - 0.2 11.3 6.3 15 5.3 0.1 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ TPR_12 PF13424.1 KXX74722.1 - 5.6e-50 167.1 0.2 4.7e-17 61.7 0.0 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KXX74722.1 - 7.2e-50 165.5 0.4 1.5e-11 43.8 0.0 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KXX74722.1 - 1.2e-13 50.5 0.2 2.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.1 KXX74722.1 - 1.2e-13 49.6 1.3 0.03 14.1 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KXX74722.1 - 1.6e-09 37.1 0.1 1.1 9.6 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat AAA_22 PF13401.1 KXX74722.1 - 2.8e-09 37.2 0.0 7.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_4 PF07721.9 KXX74722.1 - 2.3e-08 33.6 6.4 0.13 12.7 0.1 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX74722.1 - 3.1e-08 32.9 1.5 0.073 13.0 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX74722.1 - 5.2e-08 32.1 0.1 0.69 9.6 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX74722.1 - 4.4e-07 29.4 0.1 0.032 13.8 0.0 3.9 1 1 3 4 4 4 3 TPR repeat TPR_16 PF13432.1 KXX74722.1 - 1.9e-05 25.2 1.8 0.039 14.6 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat Rab5-bind PF09311.6 KXX74722.1 - 0.00014 21.7 0.1 3.2 7.6 0.1 4.0 1 1 3 4 4 4 1 Rabaptin-like protein AAA_16 PF13191.1 KXX74722.1 - 0.00032 20.7 2.0 0.0089 16.0 1.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KXX74722.1 - 0.00095 18.0 0.0 0.023 13.5 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.1 KXX74722.1 - 0.0027 17.3 0.0 31 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 KXX74722.1 - 0.0074 15.7 0.2 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KXX74722.1 - 0.036 13.2 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PPR PF01535.15 KXX74722.1 - 0.06 13.3 0.0 2.7e+02 1.9 0.0 4.5 5 0 0 5 5 4 0 PPR repeat AAA PF00004.24 KXX74722.1 - 0.12 12.5 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.10 KXX74722.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Thioredoxin PF00085.15 KXX74723.1 - 3.2e-21 74.9 0.0 3.5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX74723.1 - 0.00017 21.6 0.2 0.013 15.5 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KXX74723.1 - 0.00056 20.0 0.0 0.039 14.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KXX74723.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KXX74723.1 - 0.0021 17.6 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KXX74723.1 - 0.051 13.1 0.1 0.16 11.5 0.1 1.7 1 1 1 2 2 2 0 Redoxin Erv26 PF04148.8 KXX74725.1 - 6.8e-89 296.8 0.2 7.6e-89 296.6 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.3 KXX74725.1 - 0.02 14.5 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) QueT PF06177.6 KXX74725.1 - 0.033 14.1 1.5 0.062 13.2 1.0 1.4 1 0 0 1 1 1 0 QueT transporter Cytochrom_C_asm PF01578.15 KXX74725.1 - 0.035 13.6 0.2 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C assembly protein Claudin_2 PF13903.1 KXX74725.1 - 4.6 6.8 7.3 23 4.6 5.1 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DnaJ PF00226.26 KXX74726.1 - 3.7e-24 84.2 0.4 3.7e-24 84.2 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain zf-met PF12874.2 KXX74726.1 - 1.6e-10 40.7 9.9 4.5e-09 36.2 1.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX74726.1 - 2.1e-10 40.4 10.3 2.2e-10 40.3 2.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KXX74726.1 - 1.1e-07 31.9 7.7 0.00032 20.7 1.6 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KXX74726.1 - 1.6e-05 24.9 9.4 0.027 14.8 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KXX74726.1 - 0.00014 21.6 9.0 0.025 14.4 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KXX74726.1 - 0.00046 20.3 4.6 0.18 12.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.1 KXX74726.1 - 0.011 15.0 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.1 KXX74726.1 - 0.021 15.1 1.7 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF2256 PF10013.4 KXX74726.1 - 0.076 12.7 3.8 13 5.6 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2387 PF09526.5 KXX74726.1 - 0.089 12.7 6.0 0.059 13.2 2.3 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) 2-oxoacid_dh PF00198.18 KXX74727.1 - 5.8e-81 271.1 0.1 7.4e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KXX74727.1 - 4.5e-18 64.6 1.1 1e-17 63.5 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KXX74727.1 - 0.00095 18.7 0.3 0.52 10.0 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 KXX74727.1 - 0.028 14.7 0.1 0.71 10.2 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein DUF3614 PF12267.3 KXX74727.1 - 0.078 13.2 1.4 0.46 10.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) DUF2360 PF10152.4 KXX74727.1 - 1.3 9.3 9.2 2.4 8.4 6.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Complex1_LYR PF05347.10 KXX74728.1 - 2.4e-10 40.0 2.9 3.4e-10 39.5 2.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX74728.1 - 4e-08 33.3 1.5 6.2e-08 32.7 1.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like AA_permease PF00324.16 KXX74730.1 - 5e-60 203.1 32.6 1.5e-59 201.6 22.6 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX74730.1 - 5.2e-27 94.4 29.2 8e-27 93.8 20.3 1.2 1 0 0 1 1 1 1 Amino acid permease R3H PF01424.17 KXX74731.1 - 3.3e-12 45.9 0.0 8.3e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KXX74731.1 - 9.5e-11 41.3 1.4 2e-10 40.2 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KXX74731.1 - 0.014 15.2 0.4 0.054 13.3 0.3 2.1 1 0 0 1 1 1 0 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 KXX74732.1 - 1.4e-95 319.6 0.0 1.7e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.19 KXX74733.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX74733.1 - 1.3e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX74734.1 - 9.5e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX74734.1 - 4.2e-05 23.5 0.0 9.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KXX74734.1 - 0.00021 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KXX74734.1 - 0.007 15.0 1.5 0.0087 14.7 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KXX74734.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 KXX74734.1 - 0.029 14.8 0.4 0.039 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Glyco_hydro_53 PF07745.8 KXX74734.1 - 0.064 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 OTU PF02338.14 KXX74735.1 - 5.2e-12 46.4 0.0 8.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 KXX74735.1 - 0.0025 18.0 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.19 KXX74735.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 PB1 domain UBX PF00789.15 KXX74735.1 - 0.041 13.9 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 UBX domain Bromodomain PF00439.20 KXX74736.1 - 2.7e-43 145.7 0.5 9e-21 73.5 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KXX74736.1 - 9.7e-18 64.0 0.3 2.4e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 BAH domain AT_hook PF02178.14 KXX74736.1 - 0.32 10.8 10.4 0.17 11.6 0.7 3.2 2 0 0 2 2 2 0 AT hook motif PAT1 PF09770.4 KXX74736.1 - 5.3 5.1 30.2 16 3.6 20.9 1.9 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 KXX74738.1 - 2.5e-45 152.1 3.2 6.2e-19 67.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.18 KXX74739.1 - 4.3e-68 229.2 0.0 5.9e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KXX74739.1 - 1.3e-62 211.1 2.3 6.8e-62 208.7 2.2 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KXX74739.1 - 6e-13 48.4 0.0 2.2e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KXX74739.1 - 5.7e-05 22.0 0.0 0.00021 20.2 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KXX74739.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX74739.1 - 0.088 12.9 0.1 0.84 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain UDP-g_GGTase PF06427.6 KXX74740.1 - 2.6e-60 203.3 0.0 2.2e-58 197.0 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KXX74740.1 - 0.00012 21.4 0.3 0.00028 20.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 adh_short PF00106.20 KXX74741.1 - 6.4e-24 84.7 1.8 1.7e-22 80.1 1.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX74741.1 - 1e-08 35.0 0.2 2.1e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KXX74741.1 - 2.7e-06 27.3 0.3 7.5e-06 25.8 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX74741.1 - 0.005 16.3 0.1 0.011 15.1 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX74741.1 - 0.015 15.0 2.2 0.037 13.8 0.4 2.4 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SOG2 PF10428.4 KXX74742.1 - 4.1 5.9 17.0 5.6 5.5 11.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Coatomer_WDAD PF04053.9 KXX74743.1 - 1.5e-148 495.2 0.0 2.2e-148 494.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KXX74743.1 - 1.5e-85 287.2 0.0 2.1e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KXX74743.1 - 6.7e-51 168.4 11.2 1.6e-09 37.2 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KXX74743.1 - 0.039 12.0 8.4 0.27 9.3 0.0 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 SAC3_GANP PF03399.11 KXX74744.1 - 2.2e-23 82.9 0.0 2.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KXX74744.1 - 6.4e-18 64.8 0.0 1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Sel1 PF08238.7 KXX74745.1 - 1.4e-19 70.0 30.0 2.2e-07 31.3 0.2 7.6 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 KXX74745.1 - 0.099 12.2 0.1 0.099 12.2 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KXX74745.1 - 0.25 11.2 2.6 32 4.5 0.1 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 KXX74745.1 - 1.1 10.0 9.4 3.3 8.5 0.5 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX74745.1 - 2.1 9.1 6.6 46 5.0 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KXX74745.1 - 5.2 6.7 9.1 0.49 10.0 0.1 3.3 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.1 KXX74745.1 - 5.7 7.6 11.6 1.7 9.3 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.22 KXX74746.1 - 1.9e-46 155.6 5.8 2.6e-16 59.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-bind_2 PF08914.6 KXX74747.1 - 2.5e-26 91.2 9.0 2.9e-17 62.2 1.2 2.8 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.3 KXX74747.1 - 7.1e-19 67.4 0.4 6.9e-17 61.1 0.0 3.3 4 0 0 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 KXX74747.1 - 1.1e-12 48.4 2.7 2.5e-05 24.7 0.2 2.9 2 0 0 2 2 2 2 Rap1, DNA-binding ARID PF01388.16 KXX74747.1 - 0.018 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain IQ PF00612.22 KXX74747.1 - 0.15 11.7 18.8 1.5 8.6 2.4 3.7 3 0 0 3 3 3 0 IQ calmodulin-binding motif PepSY_TM_2 PF13703.1 KXX74748.1 - 0.36 11.0 6.8 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix HET PF06985.6 KXX74749.1 - 2.9e-22 79.3 0.0 4.5e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1227 PF06777.6 KXX74749.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) CytadhesinP1 PF12378.3 KXX74749.1 - 0.3 11.0 1.8 0.48 10.4 0.2 2.0 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein MFS_1 PF07690.11 KXX74750.1 - 7.1e-26 90.7 23.8 7.1e-26 90.7 16.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74750.1 - 8.9e-07 27.8 6.5 8.9e-07 27.8 4.5 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KXX74750.1 - 0.0078 14.3 2.5 0.013 13.6 0.1 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family SAYSvFN PF10260.4 KXX74750.1 - 0.073 12.8 2.3 0.89 9.3 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) ADH_zinc_N_2 PF13602.1 KXX74751.1 - 1.3e-13 51.8 0.0 4.2e-13 50.3 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX74751.1 - 2.9e-13 49.4 0.0 6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX74751.1 - 7.1e-06 25.7 0.2 0.00068 19.3 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KXX74751.1 - 0.0028 17.6 0.6 0.0044 17.0 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX74751.1 - 0.06 13.2 0.3 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Complex1_LYR_2 PF13233.1 KXX74752.1 - 8.9e-18 64.6 0.1 1.5e-17 63.9 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KXX74752.1 - 0.0016 18.2 0.8 0.0028 17.3 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-DHHC PF01529.15 KXX74753.1 - 1e-32 112.9 1.4 2.7e-32 111.5 1.0 1.8 1 0 0 1 1 1 1 DHHC palmitoyltransferase RRN9 PF10680.4 KXX74753.1 - 0.092 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Ery_res_leader2 PF08057.6 KXX74753.1 - 3 8.1 5.8 12 6.2 4.0 2.1 1 0 0 1 1 1 0 Erythromycin resistance leader peptide MMR_HSR1 PF01926.18 KXX74754.1 - 1.5e-16 60.3 0.0 6.2e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX74754.1 - 7.9e-08 31.9 0.0 2.9e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KXX74754.1 - 5.3e-05 23.0 0.0 0.12 12.1 0.0 2.6 3 0 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 KXX74754.1 - 7.1e-05 22.1 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KXX74754.1 - 0.00085 18.5 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KXX74754.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 KXX74754.1 - 0.038 13.1 0.0 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.22 KXX74754.1 - 0.046 14.0 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.13 KXX74754.1 - 0.056 12.4 0.0 0.22 10.4 0.0 1.8 1 1 0 1 1 1 0 Septin Miro PF08477.8 KXX74754.1 - 0.067 13.6 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Med3 PF11593.3 KXX74754.1 - 2.3 7.3 7.7 3 7.0 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 KXX74755.1 - 0.1 13.0 2.3 0.13 12.6 1.6 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_1 PF00133.17 KXX74756.1 - 4.8e-195 649.0 0.0 6.2e-195 648.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KXX74756.1 - 3.6e-25 88.5 0.0 8.3e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KXX74756.1 - 2.5e-18 65.9 1.8 3.1e-06 26.0 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KXX74756.1 - 0.00063 18.9 0.0 0.0062 15.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF463 PF04317.7 KXX74757.1 - 0.14 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 HET PF06985.6 KXX74758.1 - 4.1e-21 75.5 0.7 3.2e-20 72.7 0.5 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRN3 PF05327.6 KXX74758.1 - 0.061 11.4 1.6 0.09 10.8 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HD PF01966.17 KXX74759.1 - 0.00015 21.7 0.1 0.00022 21.1 0.1 1.4 1 0 0 1 1 1 1 HD domain Glyco_hydro_2_C PF02836.12 KXX74760.1 - 7.4e-28 97.3 0.0 3.5e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KXX74760.1 - 2.4e-19 69.5 0.0 3.8e-18 65.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain AA_permease_2 PF13520.1 KXX74761.1 - 5.6e-46 156.9 48.5 7.4e-46 156.5 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX74761.1 - 3.2e-30 104.8 44.5 4.3e-30 104.4 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease UQ_con PF00179.21 KXX74763.1 - 2.6e-13 49.5 0.0 5.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.2 KXX74763.1 - 0.00042 19.9 0.7 0.0022 17.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KXX74763.1 - 0.0017 17.9 0.5 0.0044 16.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain PBP PF01161.15 KXX74765.1 - 2.9e-09 36.9 0.0 4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_7 PF00840.15 KXX74766.1 - 3.1e-189 628.8 13.7 3.6e-189 628.6 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.3 KXX74766.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) DUF2985 PF11204.3 KXX74767.1 - 4.3e-27 93.6 5.0 1e-26 92.4 3.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) ketoacyl-synt PF00109.21 KXX74769.1 - 3.4e-67 226.6 0.1 4.1e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX74769.1 - 2.5e-08 33.7 0.0 8.8e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 KXX74769.1 - 0.00023 20.7 0.7 0.0005 19.6 0.5 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KXX74769.1 - 0.00038 19.5 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 KXX74770.1 - 4.1e-60 202.5 0.1 1.1e-59 201.1 0.1 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KXX74770.1 - 6.3e-57 193.3 0.0 1e-56 192.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KXX74770.1 - 3.4e-46 157.2 0.0 9e-46 155.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KXX74770.1 - 5.7e-40 137.3 0.1 9.4e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 KXX74770.1 - 9.6e-17 60.7 0.0 2.7e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KXX74770.1 - 6.8e-16 58.5 0.0 2.1e-15 56.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74770.1 - 1.6e-12 47.4 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KXX74770.1 - 2.6e-09 38.0 0.0 1e-08 36.0 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KXX74770.1 - 5.9e-09 36.5 0.0 3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74770.1 - 4.1e-08 32.9 0.0 8.1e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX74770.1 - 1e-07 32.0 0.0 1.2e-06 28.6 0.0 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KXX74770.1 - 1.5e-07 31.8 0.0 4.2e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KXX74770.1 - 0.0003 20.5 0.0 0.00092 18.9 0.0 1.8 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 KXX74770.1 - 0.00043 19.4 0.0 0.00085 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NmrA PF05368.8 KXX74770.1 - 0.00063 19.0 0.1 0.005 16.1 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family DREV PF05219.7 KXX74770.1 - 0.02 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 KXX74770.1 - 0.034 13.5 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF915 PF06028.6 KXX74770.1 - 0.04 13.0 0.0 0.38 9.8 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lzipper-MIP1 PF14389.1 KXX74770.1 - 0.05 13.7 0.0 20 5.3 0.0 3.0 3 0 0 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 NodS PF05401.6 KXX74770.1 - 0.083 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Tautomerase_2 PF14552.1 KXX74770.1 - 0.12 12.4 0.2 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 Tautomerase enzyme DUF4013 PF13197.1 KXX74770.1 - 0.26 10.6 0.0 0.47 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) p450 PF00067.17 KXX74771.1 - 1.8e-55 188.3 0.0 3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 KXX74772.1 - 1.2e-25 89.9 0.0 1.9e-25 89.2 0.0 1.2 1 1 0 1 1 1 1 Transferase family LVIVD PF08309.6 KXX74773.1 - 0.029 13.3 1.2 7.5 5.6 0.0 3.4 3 0 0 3 3 3 0 LVIVD repeat Pyr_redox_2 PF07992.9 KXX74774.1 - 6.2e-27 94.7 1.2 9.9e-27 94.1 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KXX74774.1 - 1.2e-13 50.3 0.0 3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KXX74774.1 - 1.9e-12 47.4 2.1 2.8e-11 43.6 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX74774.1 - 3.2e-07 30.6 0.1 0.00011 22.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KXX74774.1 - 7.5e-06 26.1 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 KXX74774.1 - 0.00012 21.7 0.0 0.00047 19.8 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 KXX74774.1 - 0.0055 16.5 2.3 2 8.1 0.0 3.1 2 1 1 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KXX74774.1 - 0.042 14.0 0.7 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.8 KXX74775.1 - 5.9e-42 143.6 0.0 7.9e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX74775.1 - 0.00063 18.5 1.9 0.004 15.9 1.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KXX74775.1 - 0.0063 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1989 PF09347.5 KXX74776.1 - 1.2e-43 148.4 0.0 2.6e-40 137.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Sugar_tr PF00083.19 KXX74778.1 - 3.1e-78 263.3 25.5 3.6e-78 263.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX74778.1 - 5.8e-27 94.3 19.5 5.8e-27 94.3 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX74778.1 - 1.8e-05 23.3 4.9 1.8e-05 23.3 3.4 2.9 2 2 1 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 KXX74778.1 - 0.00017 19.9 1.7 0.00025 19.3 1.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TFIIB PF00382.14 KXX74779.1 - 0.032 14.0 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Dynamin_N PF00350.18 KXX74780.1 - 1.4e-14 54.2 1.7 2e-13 50.4 0.0 2.9 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.22 KXX74780.1 - 0.00077 19.7 0.2 0.011 16.0 0.0 2.7 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 KXX74780.1 - 0.00095 19.1 0.0 0.014 15.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX74780.1 - 0.0044 17.5 0.2 0.027 14.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KXX74780.1 - 0.0056 15.8 0.0 0.092 11.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 IncA PF04156.9 KXX74780.1 - 0.013 15.0 0.1 0.013 15.0 0.1 4.0 3 1 1 4 4 4 0 IncA protein Adeno_IVa2 PF02456.10 KXX74780.1 - 0.028 13.0 0.6 0.054 12.1 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_16 PF13191.1 KXX74780.1 - 0.068 13.1 2.9 0.17 11.8 0.0 3.2 3 1 1 4 4 4 0 AAA ATPase domain NPV_P10 PF05531.7 KXX74780.1 - 0.76 10.0 4.2 20 5.5 0.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3713 PF12506.3 KXX74780.1 - 0.89 9.6 5.7 11 6.0 2.5 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) PRP1_N PF06424.7 KXX74780.1 - 1.2 9.4 14.7 0.6 10.4 7.0 2.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal TPR_MLP1_2 PF07926.7 KXX74780.1 - 2.5 7.8 24.5 1.9 8.2 0.1 4.3 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein Fungal_trans PF04082.13 KXX74781.1 - 2.5e-29 101.9 0.0 6e-29 100.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74781.1 - 1.2e-08 34.7 8.6 1.9e-08 34.0 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX74781.1 - 0.015 13.8 0.0 0.033 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4306 PF14154.1 KXX74781.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Nop25 PF09805.4 KXX74781.1 - 3.7 7.6 7.5 5.7 7.0 1.8 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Sugar_tr PF00083.19 KXX74782.1 - 6.4e-120 400.7 29.6 7.4e-120 400.5 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX74782.1 - 1e-20 73.7 47.3 8.3e-16 57.6 12.5 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF3154 PF11351.3 KXX74782.1 - 0.083 12.6 3.7 0.098 12.4 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3154) Mucin PF01456.12 KXX74783.1 - 0.0039 16.9 17.9 0.0039 16.9 12.4 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein DAGK_cat PF00781.19 KXX74784.1 - 2.6e-10 39.8 0.2 5.3e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GGDEF PF00990.16 KXX74784.1 - 0.022 14.3 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 GGDEF domain SH3_4 PF06347.8 KXX74784.1 - 0.067 12.7 4.9 0.96 9.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain ABC_tran PF00005.22 KXX74785.1 - 6.4e-45 152.8 1.3 1.2e-20 74.1 0.0 3.7 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 KXX74785.1 - 3e-16 60.2 4.1 2.6e-07 30.8 1.4 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KXX74785.1 - 8.3e-10 38.2 0.0 0.0013 18.0 0.0 4.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KXX74785.1 - 3.2e-09 36.4 6.1 7.5e-09 35.3 4.2 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KXX74785.1 - 5.8e-09 35.3 0.1 7.5e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX74785.1 - 4.2e-08 33.3 0.2 0.034 14.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KXX74785.1 - 5.5e-08 32.7 0.0 0.021 14.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KXX74785.1 - 2.9e-07 31.3 0.1 0.0026 18.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX74785.1 - 1.9e-06 28.0 13.0 7.3e-05 22.8 1.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KXX74785.1 - 4.6e-06 26.3 0.0 0.0089 15.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 KXX74785.1 - 1.2e-05 25.7 7.0 0.021 15.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KXX74785.1 - 2.1e-05 23.7 0.5 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KXX74785.1 - 2.3e-05 24.3 1.8 0.34 10.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 KXX74785.1 - 5.3e-05 23.6 0.0 0.7 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 KXX74785.1 - 9.2e-05 22.1 0.0 0.09 12.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KXX74785.1 - 0.0001 22.3 0.6 0.052 13.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KXX74785.1 - 0.00011 22.1 2.9 0.47 10.2 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_18 PF13238.1 KXX74785.1 - 0.00014 22.1 1.9 0.064 13.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KXX74785.1 - 0.00031 20.2 0.1 0.59 9.5 0.0 3.0 3 0 0 3 3 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KXX74785.1 - 0.00044 19.7 3.0 0.068 12.6 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family cobW PF02492.14 KXX74785.1 - 0.00046 19.6 0.0 0.66 9.3 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 KXX74785.1 - 0.00054 18.5 5.2 0.59 8.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 KXX74785.1 - 0.00082 19.2 1.6 1 9.1 0.0 3.0 3 0 0 3 3 3 2 Dynamin family ArgK PF03308.11 KXX74785.1 - 0.0015 17.4 0.5 0.53 9.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 KXX74785.1 - 0.0019 17.6 0.6 0.34 10.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KXX74785.1 - 0.005 16.9 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ABC_ATPase PF09818.4 KXX74785.1 - 0.0079 14.8 0.1 0.047 12.2 0.0 2.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class NB-ARC PF00931.17 KXX74785.1 - 0.0097 14.7 0.2 1.9 7.2 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 KXX74785.1 - 0.0098 15.7 0.1 3.5 7.5 0.0 3.1 4 0 0 4 4 2 1 AAA domain Arch_ATPase PF01637.13 KXX74785.1 - 0.015 15.0 0.8 0.6 9.7 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 KXX74785.1 - 0.022 14.2 0.0 8.3 5.8 0.0 2.9 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Arf PF00025.16 KXX74785.1 - 0.031 13.5 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 KXX74785.1 - 0.034 14.3 0.0 0.83 9.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KXX74785.1 - 0.036 12.9 0.1 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 KXX74785.1 - 0.052 13.4 0.2 13 5.7 0.0 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KXX74785.1 - 0.056 13.0 5.6 0.76 9.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 KXX74785.1 - 0.06 13.0 0.0 3.1 7.4 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.9 KXX74785.1 - 0.071 12.8 0.2 1.4 8.6 0.0 3.0 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 KXX74785.1 - 0.079 12.3 2.7 5.6 6.3 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase UPF0079 PF02367.12 KXX74785.1 - 0.1 12.2 0.1 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KXX74785.1 - 0.13 11.3 0.1 0.13 11.3 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain G-alpha PF00503.15 KXX74785.1 - 1.7 7.2 9.4 0.59 8.7 0.1 3.0 3 0 0 3 3 3 0 G-protein alpha subunit DNA_topoisoIV PF00521.15 KXX74786.1 - 2.7e-121 405.4 0.0 4.6e-121 404.6 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KXX74786.1 - 1.4e-32 112.2 2.1 3.4e-32 111.0 1.4 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KXX74786.1 - 3.9e-12 46.0 0.0 1.8e-11 43.9 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KXX74786.1 - 1.2e-10 41.0 0.0 3.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRM PF02005.11 KXX74787.1 - 4.3e-99 331.9 0.0 1.7e-98 330.0 0.0 1.9 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KXX74787.1 - 0.0026 17.7 0.1 0.0065 16.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.1 KXX74788.1 - 5.7e-09 35.5 13.6 0.00096 18.7 0.5 3.5 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KXX74788.1 - 6.3e-09 35.0 4.3 0.009 15.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX74788.1 - 1.2e-07 31.1 5.8 0.12 12.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KXX74788.1 - 0.011 15.8 1.0 0.029 14.4 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KXX74788.1 - 0.032 14.5 2.4 0.15 12.3 1.7 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX74788.1 - 0.036 14.2 0.3 0.3 11.4 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KXX74790.1 - 1.2e-08 34.4 0.0 2.4e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74790.1 - 2.9e-05 23.2 0.0 0.00026 20.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.17 KXX74791.1 - 3.7e-58 197.1 0.0 5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KXX74792.1 - 0.27 11.1 7.4 0.82 9.6 5.1 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2945 PF11160.3 KXX74793.1 - 0.051 13.3 1.6 0.1 12.4 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) VID27 PF08553.5 KXX74794.1 - 0 1140.2 0.0 0 1139.9 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein TIM-br_sig_trns PF09370.5 KXX74795.1 - 1.9e-132 440.3 0.2 2.1e-132 440.1 0.1 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KXX74795.1 - 2.1e-05 23.8 0.3 3.6e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Radical_SAM PF04055.16 KXX74795.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily VSP PF03302.8 KXX74796.1 - 0.0063 15.1 0.1 0.0092 14.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Myc_target_1 PF15179.1 KXX74796.1 - 0.017 14.6 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Myc target protein 1 DUF3262 PF11660.3 KXX74796.1 - 0.073 13.1 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Gly-zipper_YMGG PF13441.1 KXX74796.1 - 0.11 12.0 2.9 0.16 11.4 2.0 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF566 PF04484.7 KXX74797.1 - 2.1 7.7 7.1 2.4 7.5 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cu_amine_oxid PF01179.15 KXX74798.1 - 0.079 11.6 0.5 0.1 11.2 0.3 1.2 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain HCV_capsid PF01543.12 KXX74798.1 - 0.76 9.7 0.0 0.76 9.7 0.0 2.8 1 1 2 3 3 3 0 Hepatitis C virus capsid protein UPF0261 PF06792.6 KXX74799.1 - 2.2e-135 451.2 0.1 8.3e-134 446.0 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0261) TPR_12 PF13424.1 KXX74801.1 - 1.7e-38 130.4 10.6 4e-10 39.4 0.0 6.3 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KXX74801.1 - 3.7e-21 74.3 24.6 6.9e-05 22.6 0.0 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KXX74801.1 - 3.3e-08 33.9 12.7 0.095 13.4 0.0 6.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX74801.1 - 5.3e-08 32.3 6.5 0.012 15.2 0.0 5.5 4 2 1 5 5 5 2 TPR repeat TPR_4 PF07721.9 KXX74801.1 - 7.9e-07 28.9 29.8 0.036 14.4 0.2 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KXX74801.1 - 2.4e-06 27.7 18.3 1.4 9.3 2.5 6.9 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX74801.1 - 1.8e-05 24.2 25.4 0.72 9.9 0.3 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat AAA_22 PF13401.1 KXX74801.1 - 0.0001 22.4 0.0 0.00095 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KXX74801.1 - 0.0002 20.8 3.4 0.99 9.3 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX74801.1 - 0.0003 21.0 15.6 1.5 9.4 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.7 KXX74801.1 - 0.00051 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 KXX74801.1 - 0.00099 18.7 14.7 0.17 11.7 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat NB-ARC PF00931.17 KXX74801.1 - 0.0036 16.1 0.0 0.02 13.7 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KXX74801.1 - 0.0037 17.3 1.6 24 5.1 0.0 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 KXX74801.1 - 0.0077 16.2 0.2 0.073 13.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain TPR_14 PF13428.1 KXX74801.1 - 0.13 12.9 40.0 10 7.1 0.2 9.6 7 2 3 10 10 8 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 KXX74801.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPR_21 PF09976.4 KXX74801.1 - 0.61 10.0 3.3 1.4 8.8 0.6 2.9 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX74801.1 - 2.7 7.7 19.0 4.7 6.9 0.1 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 KXX74802.1 - 1.4e-39 134.3 0.0 1.4e-13 50.9 0.0 4.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX74802.1 - 5.6e-39 131.8 0.2 6.3e-09 36.1 0.0 5.6 3 1 4 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KXX74802.1 - 4.9e-31 104.9 0.0 2.2e-05 24.0 0.0 7.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KXX74802.1 - 5.5e-25 86.8 0.1 1.5e-07 31.4 0.0 5.5 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74802.1 - 2.1e-22 76.9 0.0 0.003 17.6 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat NACHT PF05729.7 KXX74802.1 - 2.5e-05 23.9 0.0 7.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX74802.1 - 0.00031 20.8 0.0 0.0031 17.6 0.0 2.7 4 0 0 4 4 4 1 AAA domain Abhydrolase_6 PF12697.2 KXX74802.1 - 0.00047 20.0 0.3 0.0062 16.4 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KXX74802.1 - 0.00076 19.5 0.1 0.028 14.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 KXX74802.1 - 0.012 14.6 0.1 3.1 6.7 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain DUF676 PF05057.9 KXX74802.1 - 0.014 14.7 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_25 PF13481.1 KXX74802.1 - 0.038 13.3 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX74802.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PGAP1 PF07819.8 KXX74802.1 - 0.048 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_30 PF13604.1 KXX74802.1 - 0.055 13.0 0.3 0.12 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 KXX74802.1 - 0.076 12.7 0.1 23 4.6 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KXX74802.1 - 0.094 12.4 0.0 0.4 10.4 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain DAP3 PF10236.4 KXX74802.1 - 0.099 11.5 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TauD PF02668.11 KXX74803.1 - 1.2e-27 97.2 0.1 2.1e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAP PF07174.6 KXX74803.1 - 0.1 11.9 1.7 0.15 11.3 1.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Amidase PF01425.16 KXX74804.1 - 9.3e-69 232.3 0.0 1.1e-68 232.0 0.0 1.1 1 0 0 1 1 1 1 Amidase HET PF06985.6 KXX74805.1 - 0.00041 20.5 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_5 PF12695.2 KXX74806.1 - 0.00037 20.2 0.0 0.0005 19.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KXX74806.1 - 0.00045 19.7 0.2 0.0044 16.4 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KXX74806.1 - 0.00081 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KXX74806.1 - 0.0025 17.1 0.0 0.0057 15.9 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KXX74806.1 - 0.007 16.2 0.1 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KXX74806.1 - 0.075 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.11 KXX74807.1 - 9.7e-28 96.8 35.8 4.2e-16 58.6 18.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily AflR PF08493.5 KXX74808.1 - 4.1e-12 45.6 0.1 6.6e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein SOG2 PF10428.4 KXX74808.1 - 0.055 12.1 1.7 0.069 11.8 0.5 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein DIPSY PF11763.3 KXX74808.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Astacin PF01400.19 KXX74809.1 - 0.001 18.4 1.5 0.046 13.1 0.4 3.3 4 0 0 4 4 4 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KXX74809.1 - 0.0058 16.3 0.1 0.041 13.6 0.2 2.2 2 1 0 2 2 2 1 Matrixin Reprolysin_4 PF13583.1 KXX74809.1 - 0.014 14.9 0.1 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX74809.1 - 0.028 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX74809.1 - 0.084 12.9 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KXX74809.1 - 0.13 11.1 0.2 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase M66 LysM PF01476.15 KXX74810.1 - 1.4e-27 95.3 0.4 6.9e-05 22.6 0.0 6.4 6 0 0 6 6 6 6 LysM domain HET PF06985.6 KXX74812.1 - 0.0012 19.0 0.0 0.0031 17.6 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 KXX74813.1 - 1e-11 44.5 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.19 KXX74813.1 - 0.0087 16.0 0.0 0.12 12.3 0.0 2.0 1 1 1 2 2 2 1 Response regulator receiver domain Glyco_hydro_43 PF04616.9 KXX74814.1 - 1.3e-50 172.1 4.8 1.6e-50 171.8 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KXX74814.1 - 1.2e-38 132.0 1.4 2.1e-38 131.3 1.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 KXX74814.1 - 0.0016 17.8 1.9 0.0027 17.1 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF2252 PF10009.4 KXX74815.1 - 8.5e-119 396.8 0.3 1e-118 396.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.18 KXX74815.1 - 8.1e-07 29.0 0.6 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 KXX74815.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Myosin_head PF00063.16 KXX74815.1 - 0.21 9.5 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Glyco_hydro_18 PF00704.23 KXX74816.1 - 2e-73 247.7 0.0 2.9e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KXX74816.1 - 6.8e-08 32.3 8.7 6.8e-08 32.3 6.0 2.6 2 0 0 2 2 2 1 Chitin recognition protein Lipase_GDSL_2 PF13472.1 KXX74817.1 - 4.9e-12 46.3 0.0 1.7e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX74817.1 - 8.3e-06 25.7 0.8 4.7e-05 23.3 0.5 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Abhydrolase_6 PF12697.2 KXX74818.1 - 5.8e-17 62.3 9.3 8.8e-17 61.7 6.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX74818.1 - 2.2e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX74818.1 - 5e-07 29.5 0.0 2.3e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2048 PF09752.4 KXX74818.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 KXX74818.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase SnoaL_4 PF13577.1 KXX74819.1 - 9.9e-42 141.8 3.3 1.7e-18 66.7 0.0 3.2 3 0 0 3 3 3 3 SnoaL-like domain HoxA13_N PF12284.3 KXX74819.1 - 0.036 14.2 0.5 0.072 13.2 0.4 1.4 1 0 0 1 1 1 0 Hox protein A13 N terminal SnoaL_2 PF12680.2 KXX74819.1 - 0.061 13.7 2.8 2.5 8.5 0.0 4.0 4 1 1 5 5 5 0 SnoaL-like domain Dickkopf_N PF04706.7 KXX74820.1 - 2.8 8.1 7.6 0.26 11.4 0.4 2.4 2 1 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Nup54 PF13874.1 KXX74821.1 - 0.0078 15.8 0.3 0.011 15.3 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 IncA PF04156.9 KXX74821.1 - 0.059 12.9 0.3 0.069 12.7 0.2 1.1 1 0 0 1 1 1 0 IncA protein p25-alpha PF05517.7 KXX74821.1 - 0.062 13.5 0.0 0.094 12.9 0.0 1.4 1 1 0 1 1 1 0 p25-alpha EzrA PF06160.7 KXX74821.1 - 0.069 11.3 0.1 0.094 10.8 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Abhydrolase_3 PF07859.8 KXX74822.1 - 2.1e-21 76.4 0.0 4.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX74822.1 - 0.0075 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.11 KXX74823.1 - 2e-36 125.4 56.4 1.6e-35 122.4 39.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 KXX74823.1 - 0.3 9.1 13.2 0.37 8.8 5.6 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector KGG PF10685.4 KXX74824.1 - 1.9e-28 97.7 20.8 9.8e-13 47.6 1.7 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif TPR_12 PF13424.1 KXX74825.1 - 4.3e-28 97.0 18.0 9.3e-11 41.5 1.0 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KXX74825.1 - 1.5e-16 59.6 11.3 4.2e-05 23.3 0.2 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX74825.1 - 1.1e-12 47.4 0.0 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain TPR_16 PF13432.1 KXX74825.1 - 9.3e-10 38.9 3.5 0.00038 21.0 0.3 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KXX74825.1 - 1.4e-08 34.7 0.7 0.0093 16.0 0.0 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KXX74825.1 - 3.5e-08 32.7 3.3 0.076 12.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX74825.1 - 1.1e-07 31.8 7.0 0.79 10.5 0.1 5.2 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX74825.1 - 1.7e-07 30.4 1.4 1.2 9.1 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX74825.1 - 2.9e-06 26.8 1.9 0.069 12.8 0.3 3.2 1 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KXX74825.1 - 2.6e-05 23.6 0.1 7.2 6.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 KXX74825.1 - 4.7e-05 23.5 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 KXX74825.1 - 0.00022 21.5 5.1 0.15 12.4 0.1 3.8 2 1 3 5 5 4 3 Tetratricopeptide repeat PGAP1 PF07819.8 KXX74825.1 - 0.0004 20.0 0.0 0.00092 18.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.1 KXX74825.1 - 0.0004 20.4 1.6 0.002 18.1 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain DUF676 PF05057.9 KXX74825.1 - 0.0013 18.0 0.0 0.0061 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PPR_1 PF12854.2 KXX74825.1 - 0.0025 17.2 0.5 32 4.1 0.0 4.2 4 0 0 4 4 4 0 PPR repeat PPR PF01535.15 KXX74825.1 - 0.0037 17.1 0.4 66 3.8 0.0 4.4 4 0 0 4 4 4 0 PPR repeat TPR_6 PF13174.1 KXX74825.1 - 0.012 15.9 0.1 23 5.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX74825.1 - 0.015 15.4 0.2 54 4.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KXX74825.1 - 0.018 14.8 0.2 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPR_20 PF14561.1 KXX74825.1 - 0.061 13.4 12.5 3.3 7.8 0.2 4.5 3 1 2 5 5 4 0 Tetratricopeptide repeat PRiA4_ORF3 PF07929.6 KXX74825.1 - 0.093 12.1 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein KAR9 PF08580.5 KXX74826.1 - 0.18 10.0 1.7 0.29 9.3 1.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WD40 PF00400.27 KXX74827.1 - 3.3e-18 64.7 6.3 0.0022 17.7 0.0 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KXX74828.1 - 9.1e-09 34.3 0.3 2.1e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74828.1 - 8.7e-06 25.5 10.2 8.7e-06 25.5 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.1 KXX74829.1 - 1.5e-11 44.8 0.0 3.2e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX74829.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KXX74829.1 - 0.00079 19.9 0.0 0.012 15.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0086 PF01868.11 KXX74830.1 - 1.7e-24 85.2 0.1 2.7e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.16 KXX74831.1 - 1.4e-18 66.5 0.0 4e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase PUA PF01472.15 KXX74832.1 - 8.8e-14 51.0 0.1 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 PUA domain DUF1772 PF08592.6 KXX74833.1 - 0.00043 20.0 0.7 0.0054 16.4 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) Pkinase PF00069.20 KXX74834.1 - 1.3e-28 99.8 0.0 3e-28 98.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74834.1 - 1.3e-08 34.2 0.1 0.0014 17.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KXX74834.1 - 0.14 11.8 1.2 0.34 10.5 0.1 2.0 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX74834.1 - 0.2 10.5 0.1 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pantoate_ligase PF02569.10 KXX74835.1 - 3e-81 272.2 0.0 5.8e-81 271.3 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase NST1 PF13945.1 KXX74836.1 - 4.4e-58 196.4 5.2 4.4e-58 196.4 3.6 4.8 2 2 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 KXX74837.1 - 3.2e-46 156.6 0.0 3.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX74837.1 - 3.5e-15 56.5 0.0 4.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX74837.1 - 3.3e-06 26.4 0.0 4.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KXX74837.1 - 0.024 13.8 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KXX74837.1 - 0.033 13.6 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KXX74837.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 KXX74838.1 - 2.1e-08 34.1 0.1 2.2e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Inhibitor_I78 PF11720.3 KXX74839.1 - 6.8e-12 44.9 0.0 8e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KXX74839.1 - 0.0007 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.3 KXX74839.1 - 0.095 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) adh_short PF00106.20 KXX74840.1 - 4.6e-07 29.8 0.2 8.9e-05 22.4 0.2 2.6 2 1 0 2 2 2 2 short chain dehydrogenase DUF2039 PF10217.4 KXX74840.1 - 0.0025 17.7 0.2 0.0048 16.8 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Ofd1_CTDD PF10637.4 KXX74840.1 - 0.46 9.5 1.8 16 4.5 0.0 2.7 2 1 0 3 3 3 0 Oxoglutarate and iron-dependent oxygenase degradation C-term F-box PF00646.28 KXX74841.1 - 0.028 14.0 0.5 0.087 12.5 0.1 2.0 2 0 0 2 2 2 0 F-box domain DUF1049 PF06305.6 KXX74842.1 - 0.032 13.7 0.1 0.032 13.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 KXX74842.1 - 0.045 14.1 0.3 0.045 14.1 0.2 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tweety PF04906.8 KXX74842.1 - 0.081 11.3 0.1 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Tweety MFS_2 PF13347.1 KXX74842.1 - 0.081 11.3 0.0 0.082 11.2 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Shisa PF13908.1 KXX74842.1 - 1.5 8.9 13.7 7.9 6.6 8.1 2.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 KXX74842.1 - 8.4 5.9 9.3 24 4.4 6.5 1.8 1 1 0 1 1 1 0 IncA protein AA_permease_2 PF13520.1 KXX74843.1 - 4.8e-78 262.5 30.3 5.8e-78 262.3 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX74843.1 - 8e-19 67.3 27.3 2.2e-18 65.8 18.9 1.6 1 1 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 KXX74844.1 - 2.7e-46 157.7 0.0 2e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KXX74844.1 - 4.8e-10 40.2 0.0 1e-09 39.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lactamase_B_2 PF12706.2 KXX74845.1 - 2.3e-20 72.9 0.0 3.1e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KXX74845.1 - 4.7e-08 32.8 4.0 2.4e-07 30.5 1.8 2.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX74845.1 - 0.00014 21.5 4.5 0.0063 16.1 1.1 2.7 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Glyco_hydro_61 PF03443.9 KXX74846.1 - 4.1e-44 150.9 0.0 7.3e-44 150.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ldh_1_N PF00056.18 KXX74847.1 - 1.7e-44 151.0 0.0 3.8e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KXX74847.1 - 7.4e-43 146.2 0.0 1.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KXX74847.1 - 2.6e-05 23.0 0.0 3.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KXX74847.1 - 0.083 13.1 0.4 0.39 11.0 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain V-SNARE_C PF12352.3 KXX74848.1 - 2.1e-14 53.3 0.5 2.1e-14 53.3 0.4 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KXX74848.1 - 6.6e-05 22.5 0.0 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 KXX74848.1 - 0.0079 15.4 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.7 KXX74848.1 - 0.066 12.7 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Allexi_40kDa PF05549.6 KXX74848.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.7 KXX74848.1 - 0.2 11.3 2.4 1.3 8.7 0.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 KXX74848.1 - 0.2 11.1 2.6 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.2 KXX74848.1 - 0.24 10.6 10.5 0.029 13.6 3.9 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain KxDL PF10241.4 KXX74848.1 - 1.7 8.6 4.3 9.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein FliD_N PF02465.13 KXX74848.1 - 5.2 7.4 7.1 3.3 8.1 0.3 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TPK_B1_binding PF04265.9 KXX74849.1 - 1.1e-23 82.6 0.0 1.7e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 KXX74849.1 - 4.8e-20 71.3 0.0 8e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Gemini_mov PF01708.11 KXX74850.1 - 0.059 12.9 1.4 0.11 12.0 1.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Whi5 PF08528.6 KXX74851.1 - 1.3e-09 37.3 0.0 2.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Whi5 like WD40 PF00400.27 KXX74852.1 - 1.2e-50 167.5 25.0 3.5e-13 48.8 0.6 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat NACHT PF05729.7 KXX74852.1 - 8.8e-24 84.0 0.0 1.5e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KXX74852.1 - 4.2e-06 25.2 2.4 1.4 6.9 0.0 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 AAA_19 PF13245.1 KXX74852.1 - 0.0097 15.6 0.0 0.039 13.6 0.0 2.1 1 1 0 1 1 1 1 Part of AAA domain PD40 PF07676.7 KXX74852.1 - 0.05 13.2 0.7 67 3.2 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 KXX74852.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1258 PF06869.7 KXX74852.1 - 0.13 11.2 3.7 2.2 7.3 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1258) bPH_4 PF06713.6 KXX74852.1 - 0.15 11.9 0.1 17 5.3 0.0 3.4 3 1 1 4 4 4 0 Bacterial PH domain Hydrolase PF00702.21 KXX74853.1 - 1.4e-22 81.1 0.0 9.1e-22 78.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KXX74853.1 - 3.9e-21 75.1 0.0 1e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KXX74853.1 - 4.3e-19 69.4 0.0 9.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX74853.1 - 0.00016 21.5 1.4 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KXX74853.1 - 0.0016 18.0 1.2 0.03 13.9 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KXX74853.1 - 0.019 14.2 0.4 1.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase OmpH PF03938.9 KXX74853.1 - 0.75 9.7 10.1 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Atrophin-1 PF03154.10 KXX74853.1 - 3.8 5.5 20.1 0.018 13.2 7.6 1.6 2 0 0 2 2 2 0 Atrophin-1 family SNF2_N PF00176.18 KXX74858.1 - 3.8e-74 249.1 0.6 7.1e-74 248.2 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX74858.1 - 2.9e-14 52.7 0.0 7.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX74858.1 - 2.9e-08 33.7 0.0 6.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KXX74858.1 - 0.0008 18.3 0.1 0.29 9.9 0.0 2.5 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 KXX74858.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 MFS_1 PF07690.11 KXX74859.1 - 5e-14 51.7 20.3 5e-14 51.7 14.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KXX74860.1 - 3.6e-30 104.9 0.1 5e-29 101.1 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KXX74861.1 - 2.7e-25 89.5 0.8 3.7e-25 89.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX74861.1 - 0.0002 21.1 0.0 0.00046 19.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX74861.1 - 0.00064 19.3 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2789 PF10982.3 KXX74861.1 - 0.025 14.5 0.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) GMC_oxred_N PF00732.14 KXX74862.1 - 4e-31 108.2 0.0 2e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX74862.1 - 4.2e-30 104.9 0.0 1.3e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KXX74862.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX74862.1 - 0.0026 16.6 0.0 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KXX74862.1 - 0.0036 16.2 0.2 0.25 10.1 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX74862.1 - 0.038 14.0 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX74862.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1883 PF08980.5 KXX74862.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) FAD_binding_3 PF01494.14 KXX74862.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain peroxidase PF00141.18 KXX74863.1 - 1.2e-86 289.9 0.0 2.9e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 Peroxidase EthD PF07110.6 KXX74863.1 - 0.11 13.4 0.9 0.22 12.4 0.2 1.8 2 0 0 2 2 2 0 EthD domain Acetyltransf_7 PF13508.1 KXX74865.1 - 3.4e-07 30.3 0.0 6.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX74865.1 - 3.4e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX74865.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDUF_B8 PF05821.6 KXX74866.1 - 0.00011 21.9 0.3 0.00017 21.3 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Herpes_gE PF02480.11 KXX74868.1 - 0.012 13.9 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 KXX74868.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Conotoxin PF02950.12 KXX74868.1 - 0.027 15.2 0.0 0.058 14.2 0.0 1.6 1 0 0 1 1 1 0 Conotoxin Shisa PF13908.1 KXX74868.1 - 0.044 13.9 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator MtrF PF09472.5 KXX74868.1 - 0.12 11.6 1.7 0.27 10.5 1.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Adeno_E3_CR2 PF02439.10 KXX74868.1 - 0.29 10.6 3.1 0.52 9.9 2.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1469 PF07332.6 KXX74868.1 - 0.38 10.4 2.7 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Pkinase PF00069.20 KXX74869.1 - 3.2e-63 213.3 0.0 7.3e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74869.1 - 3.8e-27 94.9 0.0 5.9e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KXX74869.1 - 2.3e-13 50.1 0.0 4.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KXX74869.1 - 1e-07 31.2 0.0 1.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KXX74869.1 - 3.1e-06 27.1 0.0 0.0035 17.1 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 KXX74869.1 - 0.0049 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 KXX74869.1 - 0.055 13.2 0.1 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 KXX74869.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KXX74869.1 - 0.13 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.19 KXX74870.1 - 1.5e-21 76.5 26.3 3.3e-12 45.7 7.6 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 KXX74871.1 - 3.6e-09 35.8 0.1 1.7e-08 33.6 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74871.1 - 7.8e-09 35.2 13.9 7.8e-09 35.2 9.7 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 KXX74873.1 - 0.0052 16.7 10.5 0.015 15.2 7.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KXX74873.1 - 0.11 12.5 0.5 0.24 11.4 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 KXX74873.1 - 1 9.7 7.2 0.11 12.8 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 KXX74873.1 - 1.8 8.8 8.0 3.6 7.9 5.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 KXX74873.1 - 4.5 7.1 12.1 15 5.5 7.9 2.0 1 1 0 1 1 1 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 KXX74873.1 - 4.9 6.9 7.9 0.55 9.9 1.9 2.0 1 1 1 2 2 2 0 Sperm tail C-terminal domain eIF-3_zeta PF05091.7 KXX74874.1 - 8.6e-198 658.1 0.0 1.1e-197 657.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KXX74874.1 - 0.0077 15.6 0.1 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF569) CBFB_NFYA PF02045.10 KXX74875.1 - 6.5e-30 103.4 4.3 1.4e-29 102.3 3.0 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Mucin PF01456.12 KXX74875.1 - 3.8 7.2 8.9 9.3 6.0 6.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein LSM PF01423.17 KXX74876.1 - 5.3e-15 54.7 0.0 8e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KXX74876.1 - 0.0029 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Antimicrobial_8 PF08103.6 KXX74876.1 - 0.083 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Uperin family DRMBL PF07522.9 KXX74877.1 - 5.6e-30 103.6 0.0 1.1e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KXX74877.1 - 2e-12 47.0 0.0 4.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX74877.1 - 0.091 12.4 0.4 0.28 10.8 0.2 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Methyltransf_12 PF08242.7 KXX74878.1 - 1.6e-11 44.5 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74878.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74878.1 - 6.1e-10 39.6 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74878.1 - 7.5e-09 35.3 0.0 9.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX74878.1 - 2.7e-08 34.0 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX74878.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX74878.1 - 2.3e-07 30.1 0.0 3.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX74878.1 - 4.1e-07 30.0 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX74878.1 - 2.9e-05 23.5 0.0 4.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 KXX74878.1 - 0.0049 16.1 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KXX74878.1 - 0.0079 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Hydrophobin PF01185.13 KXX74879.1 - 7.2e-05 23.1 6.2 7.2e-05 23.1 4.3 2.1 1 1 1 2 2 2 1 Fungal hydrophobin DUF2737 PF10930.3 KXX74880.1 - 0.07 12.7 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Ferric_reduct PF01794.14 KXX74881.1 - 0.00016 21.7 2.0 0.00031 20.8 1.4 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Trp_DMAT PF11991.3 KXX74882.1 - 7.5e-85 285.2 0.0 8.8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Acetyltransf_1 PF00583.19 KXX74884.1 - 0.0058 16.6 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CysG_dimeriser PF10414.4 KXX74884.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Acetyltransf_7 PF13508.1 KXX74884.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kelch_6 PF13964.1 KXX74885.1 - 8.5e-32 108.0 13.9 3.6e-09 36.3 0.0 7.4 1 1 6 7 7 7 6 Kelch motif Kelch_1 PF01344.20 KXX74885.1 - 2.2e-31 107.1 8.8 6.2e-10 38.4 0.0 7.2 7 1 0 7 7 7 5 Kelch motif Kelch_3 PF13415.1 KXX74885.1 - 1.7e-25 88.5 11.7 7.5e-06 25.9 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KXX74885.1 - 4.3e-18 64.8 19.5 1.1e-06 28.3 0.0 7.8 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX74885.1 - 3.1e-16 58.3 5.3 9.4e-06 25.1 0.0 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KXX74885.1 - 7.7e-16 57.6 6.8 0.0027 17.6 0.0 5.8 6 0 0 6 6 6 4 Kelch motif DUF1668 PF07893.8 KXX74885.1 - 0.098 11.7 0.5 0.67 9.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1668) PQQ_3 PF13570.1 KXX74885.1 - 0.13 12.5 11.1 2 8.7 0.1 4.9 5 0 0 5 5 5 0 PQQ-like domain GTP_EFTU PF00009.22 KXX74886.1 - 0.0073 15.7 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ank_2 PF12796.2 KXX74887.1 - 7.8e-63 208.8 0.0 5.8e-17 61.8 0.0 6.4 2 1 5 7 7 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX74887.1 - 2.1e-44 147.1 0.8 3.1e-07 29.8 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KXX74887.1 - 2.7e-38 129.1 8.7 7.3e-08 32.4 0.0 8.2 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX74887.1 - 9.9e-35 115.1 0.0 8.1e-05 22.4 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KXX74887.1 - 5.2e-34 116.0 2.9 8.1e-06 26.2 0.0 7.2 4 2 1 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 KXX74887.1 - 1.5e-08 34.4 0.0 3.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX74887.1 - 8.7e-05 22.6 0.0 0.00043 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX74887.1 - 0.00038 20.4 0.0 0.0013 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KXX74887.1 - 0.0013 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KXX74887.1 - 0.0027 17.5 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX74887.1 - 0.021 14.6 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX74887.1 - 0.024 14.0 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KXX74887.1 - 0.028 15.2 0.0 0.1 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KXX74887.1 - 0.035 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KXX74887.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KXX74887.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.10 KXX74887.1 - 0.25 11.0 0.0 0.5 10.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KXX74887.1 - 0.26 10.1 0.0 0.56 9.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PhoD PF09423.5 KXX74889.1 - 2.4e-159 530.7 1.4 2.8e-159 530.5 0.9 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 KXX74889.1 - 0.024 14.5 0.0 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_7 PF00840.15 KXX74890.1 - 3.8e-201 668.0 12.9 4.4e-201 667.8 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Telomerase_RBD PF12009.3 KXX74891.1 - 4.4e-42 143.2 0.6 1e-41 142.0 0.4 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KXX74891.1 - 2.3e-14 53.3 0.0 6.2e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4419 PF14388.1 KXX74892.1 - 5.5e-71 239.2 0.0 2.8e-70 236.9 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4419) RhoGEF PF00621.15 KXX74893.1 - 2.6e-33 115.4 1.0 3.5e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 KXX74893.1 - 1.4e-09 37.8 4.2 5.4e-09 35.9 2.6 2.2 1 1 1 2 2 2 1 BAR domain IncA PF04156.9 KXX74895.1 - 1.5e-05 24.6 9.6 1.5e-05 24.6 6.6 2.4 2 0 0 2 2 2 1 IncA protein V_ATPase_I PF01496.14 KXX74895.1 - 3.6 5.3 5.2 7.3 4.3 3.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SWIB PF02201.13 KXX74896.1 - 7.8e-29 99.1 0.5 1.8e-28 98.0 0.3 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KXX74896.1 - 1.6e-15 56.6 1.9 4e-15 55.3 1.3 1.7 2 0 0 2 2 2 1 DEK C terminal domain BTV_NS2 PF04514.7 KXX74896.1 - 0.065 12.1 5.7 0.11 11.3 3.9 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-C3HC4_3 PF13920.1 KXX74897.1 - 4.5e-06 26.2 9.8 4.5e-06 26.2 6.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cpn60_TCP1 PF00118.19 KXX74898.1 - 9.2e-135 449.9 10.0 1.1e-134 449.7 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAO PF01266.19 KXX74901.1 - 8.1e-13 47.9 0.5 1.4e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KXX74901.1 - 4.8e-12 45.5 0.0 6.6e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KXX74901.1 - 7.5e-09 34.9 1.1 1e-08 34.5 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KXX74901.1 - 4.1e-08 32.1 0.3 1.2e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KXX74901.1 - 8.5e-08 32.3 0.2 1.4e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX74901.1 - 3.7e-07 30.0 0.5 2.6e-06 27.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX74901.1 - 6.1e-07 28.6 0.0 1.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KXX74901.1 - 1.7e-06 27.4 0.3 2.4e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX74901.1 - 2.3e-06 27.8 0.0 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX74901.1 - 3.1e-05 22.9 0.1 4.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KXX74901.1 - 0.00047 18.9 3.5 0.16 10.5 0.2 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 KXX74901.1 - 0.00082 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KXX74901.1 - 0.0011 19.0 0.1 0.0031 17.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KXX74901.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KXX74901.1 - 0.019 14.3 0.1 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 KXX74901.1 - 0.021 13.9 0.3 3.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 KXX74901.1 - 0.042 13.5 0.2 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KXX74901.1 - 0.045 13.3 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.19 KXX74902.1 - 9.3e-30 103.7 1.8 3.9e-29 101.6 0.6 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX74902.1 - 1.4e-18 66.1 1.3 2.9e-18 65.1 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KXX74902.1 - 1.7e-11 44.7 2.1 1.7e-11 44.6 0.2 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX74902.1 - 0.00014 22.1 1.8 0.00042 20.5 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Defensin_2 PF01097.13 KXX74903.1 - 6.7e-05 22.5 5.6 6.7e-05 22.5 3.9 2.0 2 0 0 2 2 2 1 Arthropod defensin SprB PF13573.1 KXX74903.1 - 5.6 6.6 7.5 0.21 11.2 0.7 2.0 2 0 0 2 2 2 0 SprB repeat HET PF06985.6 KXX74904.1 - 4.3e-28 98.2 0.0 7.8e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_2-5A PF06479.7 KXX74905.1 - 5.4e-45 152.4 0.0 8.9e-45 151.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KXX74905.1 - 5.4e-38 130.6 0.0 1.6e-37 129.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74905.1 - 3e-16 59.2 0.0 7.4e-14 51.4 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase PQQ PF01011.16 KXX74905.1 - 6.3e-06 25.4 1.5 0.01 15.2 0.0 3.1 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.1 KXX74905.1 - 1.6e-05 24.4 0.1 0.00011 21.7 0.1 1.8 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 KXX74905.1 - 0.00028 19.9 0.0 0.00076 18.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KXX74905.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF217 PF02697.9 KXX74907.1 - 0.074 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1753 Terpene_synth PF01397.16 KXX74907.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Cast PF10174.4 KXX74907.1 - 0.13 10.2 0.0 0.14 10.1 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone SDA1 PF05285.7 KXX74908.1 - 0.34 10.1 8.2 0.4 9.9 5.7 1.1 1 0 0 1 1 1 0 SDA1 eIF2A PF08662.6 KXX74909.1 - 6.6e-40 136.9 5.2 4.6e-38 130.8 0.5 4.0 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 KXX74909.1 - 8.8e-05 22.4 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX74909.1 - 0.00026 20.7 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KXX74909.1 - 0.0044 16.8 0.2 15 5.6 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.17 KXX74909.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.23 KXX74910.1 - 8.7e-18 63.8 0.6 6.1e-06 25.9 0.1 4.9 5 0 0 5 5 5 4 CBS domain HEAT_2 PF13646.1 KXX74911.1 - 6.3e-24 84.0 19.0 2.5e-09 37.2 0.1 9.7 2 2 6 9 9 9 9 HEAT repeats HEAT PF02985.17 KXX74911.1 - 1.3e-20 71.5 17.9 0.0013 18.6 0.0 11.6 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 KXX74911.1 - 1.3e-14 54.1 29.8 1.9e-08 34.5 0.1 10.5 7 3 6 13 13 12 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KXX74911.1 - 1.2e-12 48.0 0.7 0.0029 17.9 0.1 7.2 3 2 4 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KXX74911.1 - 7.8e-10 38.0 0.2 9.3e-06 24.6 0.1 4.2 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KXX74911.1 - 7.3e-08 32.0 0.3 0.004 16.5 0.1 5.7 5 2 1 6 6 6 1 CLASP N terminal RIX1 PF08167.7 KXX74911.1 - 4.4e-07 29.7 0.1 0.04 13.6 0.0 4.9 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KXX74911.1 - 2.2e-06 26.3 1.3 0.013 13.8 0.1 4.9 4 1 1 5 5 5 1 Adaptin N terminal region Xpo1 PF08389.7 KXX74911.1 - 2.1e-05 24.4 0.4 0.003 17.4 0.0 3.6 3 1 1 4 4 3 1 Exportin 1-like protein Cnd1 PF12717.2 KXX74911.1 - 0.00062 19.6 1.9 2.9 7.7 0.0 4.2 3 1 1 4 4 3 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KXX74911.1 - 0.00069 18.0 0.1 0.0086 14.3 0.0 2.8 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit DUF4042 PF13251.1 KXX74911.1 - 0.00084 18.8 0.1 3.7 6.9 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) CAS_CSE1 PF03378.10 KXX74911.1 - 0.0012 17.2 0.2 0.58 8.3 0.0 3.6 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 KXX74911.1 - 0.015 15.1 2.9 0.046 13.6 0.0 3.5 5 0 0 5 5 2 0 Importin-beta N-terminal domain DUF3535 PF12054.3 KXX74911.1 - 0.015 13.9 0.4 0.054 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) Apolipoprotein PF01442.13 KXX74911.1 - 0.022 14.2 7.1 0.32 10.4 0.1 3.9 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DRIM PF07539.7 KXX74911.1 - 0.074 12.4 0.4 0.28 10.5 0.3 2.1 1 0 0 1 1 1 0 Down-regulated in metastasis ParcG PF10274.4 KXX74911.1 - 0.075 12.9 0.3 4.7 7.0 0.2 2.9 1 1 1 2 2 2 0 Parkin co-regulated protein Arm PF00514.18 KXX74911.1 - 0.53 10.1 19.4 0.94 9.4 0.0 6.8 8 0 0 8 8 6 0 Armadillo/beta-catenin-like repeat Rsa3 PF14615.1 KXX74912.1 - 9.4e-22 76.0 0.7 1.2e-21 75.7 0.5 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 RTA1 PF04479.8 KXX74913.1 - 2.9e-13 49.8 5.7 7.5e-13 48.4 3.9 1.6 1 1 0 1 1 1 1 RTA1 like protein DUF4386 PF14329.1 KXX74913.1 - 0.0024 17.3 3.0 0.0024 17.3 2.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) IF2_N PF04760.10 KXX74913.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MerC PF03203.9 KXX74913.1 - 1.6 9.1 5.6 1.9 8.8 0.3 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein Peptidase_C14 PF00656.17 KXX74915.1 - 4.9e-73 245.8 0.0 5.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KXX74915.1 - 0.14 12.0 0.5 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Extensin_2 PF04554.8 KXX74916.1 - 0.26 11.1 37.3 0.44 10.4 25.9 1.5 1 1 0 1 1 1 0 Extensin-like region EI24 PF07264.6 KXX74918.1 - 1.7e-07 30.8 14.2 5.2e-06 26.0 9.9 2.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Peptidase_M50 PF02163.17 KXX74918.1 - 0.051 12.5 0.1 0.06 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M50 Inp1 PF12634.2 KXX74919.1 - 3.8e-37 127.1 0.0 1.1e-36 125.7 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SKG6 PF08693.5 KXX74920.1 - 0.0029 16.8 2.9 0.0029 16.8 2.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KXX74920.1 - 0.22 11.0 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FmdA_AmdA PF03069.10 KXX74922.1 - 1.2e-118 396.0 0.0 1.4e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OPA3 PF07047.7 KXX74923.1 - 5.3e-41 139.5 0.7 7.4e-41 139.0 0.5 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DnaJ PF00226.26 KXX74923.1 - 0.3 10.8 3.6 5.2 6.8 0.1 2.8 2 1 0 2 2 2 0 DnaJ domain TMCO5 PF14992.1 KXX74923.1 - 0.37 9.9 4.2 1.4 7.9 0.8 2.1 2 0 0 2 2 2 0 TMCO5 family MFS_1 PF07690.11 KXX74924.1 - 2.3e-38 131.8 23.5 2.3e-38 131.8 16.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX74924.1 - 7.9e-12 44.4 17.1 7.9e-12 44.4 11.9 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 KXX74925.1 - 2.5e-13 49.5 0.9 4.8e-13 48.5 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX74925.1 - 1.8e-06 27.7 3.3 1.8e-06 27.7 2.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KXX74925.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type YqjK PF13997.1 KXX74925.1 - 0.032 14.3 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 YqjK-like protein zf-C2H2_4 PF13894.1 KXX74925.1 - 0.08 13.3 3.2 0.23 11.8 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger HET PF06985.6 KXX74926.1 - 6.8e-22 78.1 8.4 1.3e-18 67.4 1.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RRM_5 PF13893.1 KXX74927.1 - 6.2e-10 38.7 0.0 9.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX74927.1 - 4.5e-09 35.8 0.0 1.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX74927.1 - 1.6e-06 27.9 0.0 3.3e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KXX74927.1 - 0.00042 19.9 0.0 0.00075 19.1 0.0 1.5 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 KXX74927.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Pkinase PF00069.20 KXX74928.1 - 1.6e-60 204.4 0.0 2.4e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74928.1 - 2.5e-37 128.3 0.0 3.6e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX74928.1 - 3.6e-09 36.0 0.0 5.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 KXX74928.1 - 5.3e-08 32.7 0.1 5.4e-05 23.0 0.0 3.1 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 KXX74928.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.16 KXX74929.1 - 2.8e-133 444.7 37.4 9.1e-132 439.7 23.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KXX74929.1 - 1.9e-36 125.5 34.6 2.8e-36 124.9 24.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.15 KXX74930.1 - 2.1e-165 550.8 0.1 2.7e-165 550.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 POX PF07526.6 KXX74930.1 - 1.3 9.2 4.6 3 8.0 3.2 1.5 1 0 0 1 1 1 0 Associated with HOX DUF3716 PF12511.3 KXX74932.1 - 3.4e-12 45.7 6.4 5.2e-12 45.1 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Autophagy_act_C PF03987.10 KXX74933.1 - 1.3e-12 47.6 0.0 2.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain WD40 PF00400.27 KXX74934.1 - 1.9e-16 59.2 7.8 0.0006 19.5 0.1 5.8 4 1 1 5 5 5 5 WD domain, G-beta repeat Rax2 PF12768.2 KXX74934.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity HMG_box_5 PF14887.1 KXX74936.1 - 0.062 13.1 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF4463 PF14703.1 KXX74936.1 - 0.081 13.4 0.1 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Polysacc_synt_C PF14667.1 KXX74937.1 - 8.8 6.1 16.9 1.8 8.3 9.0 1.9 1 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Vps8 PF12816.2 KXX74938.1 - 8.1e-74 247.1 0.0 1.6e-73 246.1 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KXX74938.1 - 4.8e-05 22.9 0.1 0.015 14.9 0.0 3.1 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KXX74938.1 - 0.00042 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX74938.1 - 0.0015 18.4 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX74938.1 - 0.0028 17.3 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KXX74938.1 - 0.011 15.4 0.1 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger CENP-B_dimeris PF09026.5 KXX74938.1 - 0.066 13.4 1.1 0.19 12.0 0.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-Nse PF11789.3 KXX74938.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KXX74938.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3752 PF12572.3 KXX74939.1 - 1.1e-44 152.2 3.2 2.4e-44 151.1 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.1 KXX74940.1 - 2.6e-13 49.5 7.0 4e-13 48.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KXX74940.1 - 1.4e-07 31.4 5.0 2.7e-07 30.5 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KXX74940.1 - 1.8e-07 30.7 4.0 2.9e-07 30.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX74940.1 - 8.7e-06 25.3 3.9 1.4e-05 24.7 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX74940.1 - 4e-05 23.5 5.5 6.5e-05 22.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX74940.1 - 6.1e-05 22.6 2.4 9.1e-05 22.0 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX74940.1 - 0.0013 18.4 2.8 0.0028 17.4 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KXX74940.1 - 0.0051 16.3 6.3 0.0082 15.7 4.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain MSP1_C PF07462.6 KXX74940.1 - 0.071 11.4 6.8 0.14 10.5 4.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus FANCL_C PF11793.3 KXX74940.1 - 0.077 12.9 3.2 0.19 11.7 2.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KXX74940.1 - 0.083 12.6 0.4 0.22 11.2 0.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.24 KXX74940.1 - 0.21 11.3 5.6 0.37 10.5 3.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 KXX74940.1 - 0.62 9.9 4.7 1.2 9.0 3.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KXX74940.1 - 0.83 9.7 5.6 1.6 8.8 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 KXX74940.1 - 3.7 7.3 8.4 0.21 11.3 1.0 2.0 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 Presenilin PF01080.12 KXX74940.1 - 6.1 5.5 4.3 9.3 4.9 3.0 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_M16 PF00675.15 KXX74941.1 - 1.6e-56 190.1 0.4 3.2e-56 189.2 0.3 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KXX74941.1 - 2e-37 128.6 0.0 2.5e-36 125.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.8 KXX74941.1 - 0.12 12.7 0.2 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 RbsD / FucU transport protein family DUF3591 PF12157.3 KXX74942.1 - 3.3e-183 609.2 0.0 5.5e-183 608.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KXX74942.1 - 0.013 15.2 0.3 0.028 14.1 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 KXX74942.1 - 0.016 15.0 0.9 0.026 14.4 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle D-ser_dehydrat PF14031.1 KXX74943.1 - 3.4e-22 78.4 0.0 7.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KXX74943.1 - 2.5e-10 40.3 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Actin PF00022.14 KXX74944.1 - 5.2e-142 472.9 0.0 5.9e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KXX74944.1 - 2.1e-05 23.2 0.0 0.012 14.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.7 KXX74945.1 - 3.6e-44 149.4 0.4 7e-44 148.4 0.0 1.6 2 0 0 2 2 2 1 PIG-P DUF4118 PF13493.1 KXX74945.1 - 0.61 10.3 8.3 0.97 9.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF1713 PF08213.6 KXX74946.1 - 1.5e-10 40.5 21.5 1.5e-10 40.5 14.9 2.4 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KXX74946.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial protein Pet20 EF_assoc_1 PF08355.7 KXX74946.1 - 0.14 11.4 1.1 0.3 10.4 0.7 1.5 1 0 0 1 1 1 0 EF hand associated Raffinose_syn PF05691.7 KXX74947.1 - 2.8e-52 177.2 1.9 3e-43 147.4 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KXX74947.1 - 0.00021 20.0 0.9 0.00052 18.8 0.6 1.5 1 1 0 1 1 1 1 Melibiase Thioredoxin_4 PF13462.1 KXX74948.1 - 7.1e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KXX74948.1 - 0.00094 18.7 5.0 0.1 12.1 0.1 3.0 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KXX74948.1 - 0.022 14.5 0.3 0.046 13.5 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.1 KXX74948.1 - 0.03 14.5 0.0 0.065 13.4 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.20 KXX74949.1 - 2.3e-69 233.4 0.0 4e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74949.1 - 5.2e-50 169.9 0.0 8.7e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KXX74949.1 - 2e-28 98.4 0.1 5.1e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KXX74949.1 - 4.6e-18 64.8 0.4 2.7e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX74949.1 - 4.8e-16 58.6 0.1 9e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KXX74949.1 - 4.1e-13 49.6 0.1 8.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KXX74949.1 - 4.7e-08 32.3 0.0 3.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 KXX74949.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Brix PF04427.13 KXX74950.1 - 3e-37 128.1 0.1 6.4e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 Brix domain BURP PF03181.10 KXX74950.1 - 0.051 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 BURP domain Cwf_Cwc_15 PF04889.7 KXX74950.1 - 0.43 10.2 15.3 0.85 9.2 10.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 KXX74950.1 - 7 4.4 16.8 9.2 4.0 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2b PF00587.20 KXX74952.1 - 9.1e-69 230.4 0.1 1.5e-68 229.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KXX74952.1 - 4.7e-24 84.1 0.9 1.7e-23 82.3 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain LRR_4 PF12799.2 KXX74953.1 - 0.00073 19.1 7.1 6.8 6.4 0.3 6.6 3 2 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KXX74953.1 - 0.00082 19.2 7.1 13 6.2 0.0 7.3 9 0 0 9 9 9 1 Leucine Rich repeat TPT PF03151.11 KXX74954.1 - 3.3e-17 62.5 5.0 3.3e-17 62.5 3.5 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family Tuberculin PF12198.3 KXX74954.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein Methyltransf_23 PF13489.1 KXX74955.1 - 6e-14 52.0 0.0 1.5e-13 50.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX74955.1 - 4.6e-07 30.4 0.1 1.6e-05 25.4 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX74955.1 - 5.5e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX74955.1 - 2.2e-05 24.8 0.0 4.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX74955.1 - 4.8e-05 22.9 0.0 0.00019 21.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX74955.1 - 0.00035 19.6 0.0 0.00069 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KXX74955.1 - 0.0064 16.4 0.0 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 KXX74955.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KXX74955.1 - 0.11 11.8 0.0 0.29 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KXX74955.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Epimerase PF01370.16 KXX74956.1 - 3.4e-57 193.6 0.1 4.2e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX74956.1 - 1.2e-22 80.1 0.0 1.2e-21 76.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KXX74956.1 - 1.8e-21 76.1 0.1 8.1e-21 74.0 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KXX74956.1 - 3.2e-21 75.2 0.0 4.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KXX74956.1 - 3.2e-20 72.1 0.0 4.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KXX74956.1 - 2.1e-09 37.6 0.0 3.6e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX74956.1 - 6e-05 23.0 0.0 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KXX74956.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family PUF PF00806.14 KXX74957.1 - 8.1e-26 88.0 0.0 7.3e-05 22.0 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KXX74957.1 - 1.3e-13 50.3 0.0 2.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX74957.1 - 6.4e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX74957.1 - 3.7e-06 26.8 0.0 9.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 KXX74957.1 - 0.14 11.8 11.1 0.34 10.6 7.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM91_C PF14648.1 KXX74957.1 - 0.32 9.8 3.3 0.63 8.8 2.3 1.4 1 0 0 1 1 1 0 FAM91 C-terminus Zip PF02535.17 KXX74957.1 - 0.54 9.2 1.7 1.1 8.2 1.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 KXX74957.1 - 2.2 8.0 24.1 0.32 10.8 12.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 KXX74957.1 - 2.4 5.7 9.5 4 5.0 6.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 KXX74957.1 - 4.2 7.1 5.4 11 5.8 3.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 KXX74958.1 - 1.2e-70 237.6 0.0 1.9e-70 237.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74958.1 - 1.2e-53 181.8 0.1 2.2e-53 180.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KXX74958.1 - 2.6e-22 78.9 1.3 7e-22 77.6 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KXX74958.1 - 1e-06 27.9 0.0 1.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 KXX74958.1 - 5.1e-05 23.4 0.0 9.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.18 KXX74958.1 - 0.00092 19.0 5.2 0.0068 16.1 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH_11 PF15413.1 KXX74958.1 - 0.0075 16.5 0.0 0.037 14.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 KXX74958.1 - 0.018 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KXX74958.1 - 0.22 10.8 0.0 0.22 10.8 0.0 2.4 3 0 0 3 3 3 0 RIO1 family GRASP55_65 PF04495.9 KXX74959.1 - 5.4e-06 26.4 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KXX74959.1 - 5.5e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KXX74959.1 - 0.00049 20.2 0.1 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RhoGEF PF00621.15 KXX74960.1 - 1.9e-25 89.8 0.0 2.9e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.13 KXX74962.1 - 2.4e-25 88.1 0.0 2.9e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CorA PF01544.13 KXX74962.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2 PF00096.21 KXX74963.1 - 7.9e-06 25.9 20.8 0.0011 19.1 0.3 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX74963.1 - 0.015 15.5 0.4 0.015 15.5 0.3 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KXX74963.1 - 0.018 14.9 0.8 0.048 13.5 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KXX74963.1 - 0.22 11.6 4.2 0.071 13.2 0.3 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) WSC PF01822.14 KXX74964.1 - 1.8e-89 293.7 70.7 1.7e-20 72.6 8.8 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 KXX74964.1 - 4.7e-29 101.1 0.0 1.8e-27 96.0 0.0 2.7 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KXX74964.1 - 7.4e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) BIR PF00653.16 KXX74964.1 - 3.7 8.0 7.6 8.8 6.8 0.7 2.8 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Ras PF00071.17 KXX74965.1 - 1.4e-43 148.0 0.1 3.8e-42 143.4 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KXX74965.1 - 1.5e-15 57.7 0.0 2.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX74965.1 - 6.5e-10 38.5 0.0 9.1e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX74965.1 - 0.0027 16.8 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 KXX74965.1 - 0.0058 16.7 0.1 0.028 14.5 0.1 1.9 1 1 0 1 1 1 1 RNA helicase Pox_A32 PF04665.7 KXX74965.1 - 0.025 13.8 0.4 0.048 12.9 0.1 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 KXX74965.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX74965.1 - 0.082 13.0 0.1 0.22 11.6 0.1 1.8 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 KXX74965.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 KaiC SRPRB PF09439.5 KXX74965.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit STAS PF01740.16 KXX74965.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain G-alpha PF00503.15 KXX74965.1 - 0.26 9.9 1.6 1.4 7.4 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit RRN3 PF05327.6 KXX74966.1 - 2.6e-170 567.2 0.0 2.6e-170 567.2 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.16 KXX74967.1 - 0.11 12.4 10.1 0.36 10.7 4.3 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF1866 PF08952.6 KXX74967.1 - 0.12 11.9 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Prefoldin_2 PF01920.15 KXX74968.1 - 1.3e-25 89.1 5.9 1.5e-25 88.9 4.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Taxilin PF09728.4 KXX74968.1 - 0.0052 15.9 2.5 0.94 8.4 0.3 2.1 2 0 0 2 2 2 2 Myosin-like coiled-coil protein UBN2 PF14223.1 KXX74968.1 - 0.014 15.1 0.7 0.93 9.2 0.0 2.2 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF2089 PF09862.4 KXX74968.1 - 0.017 14.9 1.5 0.057 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Prefoldin PF02996.12 KXX74968.1 - 0.017 14.7 1.6 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF2205 PF10224.4 KXX74968.1 - 0.03 13.8 6.7 0.35 10.4 0.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CDC37_N PF03234.9 KXX74968.1 - 0.058 13.7 3.2 0.093 13.0 2.2 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding p25-alpha PF05517.7 KXX74968.1 - 0.076 13.2 0.5 4.4 7.5 0.0 2.0 2 0 0 2 2 2 0 p25-alpha Tho2 PF11262.3 KXX74968.1 - 0.078 12.0 0.6 0.59 9.1 0.4 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.6 KXX74968.1 - 0.091 13.1 1.2 11 6.5 0.0 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Mnd1 PF03962.10 KXX74968.1 - 0.099 12.3 3.8 0.19 11.3 2.6 1.5 1 1 0 1 1 1 0 Mnd1 family DUF3166 PF11365.3 KXX74968.1 - 0.1 13.0 2.7 3.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DASH_Dad3 PF08656.5 KXX74968.1 - 0.34 10.6 3.6 0.4 10.4 0.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 TPR_MLP1_2 PF07926.7 KXX74968.1 - 0.34 10.6 6.1 0.5 10.1 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KXX74968.1 - 0.45 10.0 4.8 1.2 8.7 3.3 1.6 1 1 0 1 1 1 0 IncA protein CBFD_NFYB_HMF PF00808.18 KXX74969.1 - 1.6e-29 101.7 0.9 2.1e-29 101.3 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX74969.1 - 2.4e-07 30.7 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KXX74969.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 KXX74969.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 KXX74969.1 - 0.049 13.9 0.1 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Tmemb_14 PF03647.8 KXX74970.1 - 1.5e-23 82.9 5.3 1.7e-23 82.7 3.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 KXX74970.1 - 0.0052 17.0 0.4 0.013 15.7 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF3792 PF12670.2 KXX74970.1 - 0.58 10.0 3.5 1.3 8.9 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Cmc1 PF08583.5 KXX74971.1 - 1.4e-16 60.0 2.2 1.7e-16 59.7 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 KXX74971.1 - 0.016 14.5 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MobA_MobL PF03389.10 KXX74971.1 - 0.036 13.4 0.3 0.04 13.3 0.2 1.0 1 0 0 1 1 1 0 MobA/MobL family GCK PF07802.6 KXX74971.1 - 0.24 11.5 2.8 0.45 10.6 1.5 1.7 1 1 1 2 2 2 0 GCK domain DHDPS PF00701.17 KXX74972.1 - 1.3e-39 135.5 0.0 1.6e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_5 PF12695.2 KXX74972.1 - 0.018 14.7 0.1 0.04 13.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 KXX74974.1 - 1.5e-48 160.9 20.0 9.6e-12 44.3 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KXX74974.1 - 4.8e-05 23.1 9.3 0.036 13.7 0.4 4.0 1 1 3 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 KXX74974.1 - 0.0037 17.0 0.0 0.52 10.1 0.0 3.2 3 0 0 3 3 3 1 YmzC-like protein Kelch_6 PF13964.1 KXX74974.1 - 0.03 14.5 0.2 0.57 10.4 0.0 3.1 4 0 0 4 4 4 0 Kelch motif IKI3 PF04762.7 KXX74974.1 - 0.037 11.8 2.5 0.38 8.4 0.0 2.1 2 0 0 2 2 2 0 IKI3 family GSDH PF07995.6 KXX74975.1 - 2.8e-06 26.6 1.5 2.3e-05 23.6 0.3 2.7 2 1 1 3 3 3 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KXX74975.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KXX74975.1 - 0.06 12.4 0.1 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pkinase PF00069.20 KXX74976.1 - 1e-31 110.0 0.0 1.7e-31 109.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74976.1 - 8.3e-07 28.3 0.0 0.02 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Terpene_synth_C PF03936.11 KXX74977.1 - 4.4e-14 52.3 0.0 1.1e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1604 PF07713.8 KXX74979.1 - 1.5e-39 133.6 1.2 4.8e-39 132.0 0.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KXX74979.1 - 4.9e-06 26.2 2.4 5.8e-06 25.9 0.5 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KXX74979.1 - 0.0064 16.3 1.1 0.026 14.3 0.1 2.6 3 0 0 3 3 3 1 DExH-box splicing factor binding site Pkinase PF00069.20 KXX74980.1 - 2e-74 250.0 0.0 3.1e-74 249.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX74980.1 - 6.8e-39 133.5 0.0 1.3e-38 132.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KXX74980.1 - 8.1e-19 66.8 0.1 1.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KXX74980.1 - 7e-07 28.5 0.1 1.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KXX74980.1 - 0.00017 20.6 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX74980.1 - 0.00081 19.1 1.6 0.0017 18.1 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KXX74980.1 - 0.0075 15.5 0.1 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KXX74980.1 - 0.025 13.9 0.1 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KXX74980.1 - 0.05 13.1 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KXX74980.1 - 0.055 12.8 0.0 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DOPA_dioxygen PF08883.6 KXX74981.1 - 7.5e-30 103.0 0.0 1.1e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF2014 PF09427.5 KXX74982.1 - 4.8e-110 366.7 6.6 6.7e-110 366.3 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KXX74982.1 - 2.8e-17 62.1 0.8 5.4e-17 61.2 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4110 PF13422.1 KXX74982.1 - 0.045 13.5 0.6 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) UvrD_C PF13361.1 KXX74984.1 - 1.2e-75 255.1 0.0 1.6e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KXX74984.1 - 7.6e-61 206.1 0.0 3.4e-59 200.7 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KXX74984.1 - 2.4e-14 53.3 0.0 8.5e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KXX74984.1 - 4.7e-11 42.2 0.9 1.9e-10 40.3 0.4 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_12 PF13087.1 KXX74984.1 - 1.2e-05 24.8 0.0 8.5e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KXX74984.1 - 4.4e-05 23.1 0.1 0.39 10.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KXX74984.1 - 0.00035 20.2 3.0 0.0014 18.2 0.1 2.5 3 0 0 3 3 3 1 AAA domain Uteroglobin PF01099.12 KXX74985.1 - 0.026 14.3 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Uteroglobin family CcmD PF04995.9 KXX74985.1 - 0.11 12.1 0.6 0.43 10.3 0.4 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) G-alpha PF00503.15 KXX74986.1 - 1.7e-133 445.1 1.0 2e-133 444.8 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KXX74986.1 - 2.4e-15 56.2 1.3 2.9e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KXX74986.1 - 0.0002 20.8 0.0 0.00089 18.7 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KXX74986.1 - 0.0023 18.4 0.1 3.3 8.2 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KXX74986.1 - 0.0035 16.5 2.6 0.2 10.7 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KXX74986.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KXX74986.1 - 0.038 13.4 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 KXX74986.1 - 0.051 12.3 0.1 0.13 11.0 0.0 1.5 1 1 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 KXX74986.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KXX74986.1 - 0.13 12.2 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEAT_2 PF13646.1 KXX74988.1 - 3.2e-07 30.5 5.0 0.00021 21.5 0.2 4.6 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KXX74988.1 - 3.5e-07 29.7 1.7 0.21 11.7 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Cohesin_HEAT PF12765.2 KXX74988.1 - 0.0026 17.6 0.6 7.8 6.5 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion DUF3734 PF12536.3 KXX74988.1 - 0.0027 17.7 0.1 0.14 12.3 0.1 3.5 2 1 0 2 2 2 1 Patatin phospholipase HEAT_EZ PF13513.1 KXX74988.1 - 0.0072 16.7 10.5 0.24 11.9 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat SpoVR PF04293.8 KXX74988.1 - 0.014 13.8 0.2 0.038 12.3 0.1 1.7 1 0 0 1 1 1 0 SpoVR like protein DUF165 PF02592.10 KXX74988.1 - 0.26 11.4 0.0 0.59 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 DUF543 PF04418.7 KXX74989.1 - 7e-30 102.8 0.0 7.6e-30 102.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) RasGEF PF00617.14 KXX74990.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain DUF2709 PF10915.3 KXX74990.1 - 0.077 11.9 0.1 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) GED PF02212.13 KXX74990.1 - 0.12 12.3 0.3 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Dynamin GTPase effector domain DicB PF05358.6 KXX74990.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 DicB protein D123 PF07065.9 KXX74991.1 - 3.7e-72 242.9 1.9 7.6e-69 232.0 1.3 3.7 1 1 0 1 1 1 1 D123 Urb2 PF10441.4 KXX74992.1 - 7.5e-63 212.1 1.0 3.2e-62 210.0 0.4 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family cwf21 PF08312.7 KXX74993.1 - 1.1e-17 63.5 16.3 1.1e-17 63.5 11.3 2.1 2 0 0 2 2 2 1 cwf21 domain BTV_NS2 PF04514.7 KXX74993.1 - 8.6 5.1 18.5 10 4.8 12.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Fungal_trans PF04082.13 KXX74994.1 - 1.8e-15 56.5 1.6 3.1e-15 55.7 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KXX74994.1 - 1.5e-07 31.3 12.1 0.0001 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX74994.1 - 4.3e-05 23.5 13.3 0.0041 17.3 3.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX74994.1 - 0.0002 21.5 14.4 0.035 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RasGEF PF00617.14 KXX74995.1 - 1.2e-47 162.0 0.1 2.1e-47 161.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KXX74995.1 - 2.7e-25 88.4 0.3 6.7e-25 87.2 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KXX74995.1 - 3.9e-16 58.1 0.1 9.1e-16 56.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX74995.1 - 4.4e-14 51.7 0.2 9.4e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX74995.1 - 1.5e-13 49.9 0.1 3.3e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KXX74995.1 - 2.6e-06 27.1 0.0 6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 WW domain Glyco_hydro_16 PF00722.16 KXX74996.1 - 1.9e-13 50.0 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1771 PF08590.5 KXX74997.1 - 3.6e-22 78.1 7.8 6.6e-22 77.3 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KXX74997.1 - 4.9e-16 58.6 0.4 9.4e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 Smr domain PAT1 PF09770.4 KXX74997.1 - 0.44 8.7 4.1 0.52 8.5 2.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_16 PF13191.1 KXX74998.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.22 KXX75000.1 - 5.9e-47 157.3 6.4 1.3e-17 63.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 KXX75001.1 - 1.1e-97 327.3 0.0 1.5e-94 317.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KXX75001.1 - 5e-25 86.4 7.9 8.9e-08 31.7 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KXX75001.1 - 0.019 13.1 0.6 0.047 11.8 0.2 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX75001.1 - 0.025 13.3 0.0 4 6.0 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like ATP_bind_3 PF01171.15 KXX75002.1 - 1e-35 122.8 0.0 3.9e-23 81.8 0.0 2.4 2 0 0 2 2 2 2 PP-loop family Utp13 PF08625.6 KXX75002.1 - 0.13 11.9 0.0 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain PPTA PF01239.17 KXX75003.1 - 8.2e-31 104.0 12.5 1e-07 30.9 0.6 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CRISPR_Cse2 PF09485.5 KXX75003.1 - 0.0023 18.0 0.2 0.005 16.8 0.1 1.6 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) Sporozoite_P67 PF05642.6 KXX75003.1 - 0.51 8.1 3.7 0.62 7.8 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 KXX75003.1 - 0.98 9.4 14.7 1.8 8.6 10.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med3 PF11593.3 KXX75003.1 - 1.7 7.7 8.7 2.5 7.2 6.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 KXX75004.1 - 0.05 13.5 0.3 5.1 7.1 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Fungal_lectin PF07938.7 KXX75004.1 - 0.13 11.5 1.8 0.3 10.3 0.3 1.9 1 1 1 2 2 2 0 Fungal fucose-specific lectin HCMVantigenic_N PF12154.3 KXX75004.1 - 0.24 11.3 1.1 0.44 10.4 0.8 1.4 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Herpes_BLRF2 PF05812.7 KXX75006.1 - 0.028 14.2 0.5 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein His_Phos_2 PF00328.17 KXX75008.1 - 1.8e-06 27.5 0.1 0.00074 18.9 0.0 2.4 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) Mito_carr PF00153.22 KXX75009.1 - 1.5e-67 223.3 5.1 1.3e-25 88.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein NAP PF00956.13 KXX75010.1 - 1.1e-16 60.6 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Metallophos_2 PF12850.2 KXX75011.1 - 1.6e-05 24.7 0.0 3.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX75011.1 - 1.7e-05 24.3 0.6 0.00012 21.5 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2278 PF10042.4 KXX75013.1 - 1.4e-61 207.7 0.0 1.8e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 KXX75013.1 - 2.1e-06 27.7 0.7 5.6e-06 26.4 0.5 1.7 1 1 0 1 1 1 1 Lamin Tail Domain Exo_endo_phos_2 PF14529.1 KXX75014.1 - 0.00095 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KXX75014.1 - 0.0018 18.2 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_4 PF01565.18 KXX75015.1 - 3.6e-24 84.8 2.2 4.8e-24 84.4 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KXX75015.1 - 3.5e-07 30.0 0.0 8.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DLH PF01738.13 KXX75015.1 - 0.24 10.6 1.7 0.41 9.9 1.2 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family AMP-binding PF00501.23 KXX75016.1 - 3.5e-81 272.7 0.2 7.7e-81 271.6 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KXX75016.1 - 1e-78 264.3 0.2 1.1e-77 260.9 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX75016.1 - 2e-53 180.7 0.2 8.4e-51 172.2 0.0 2.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KXX75016.1 - 5.5e-48 163.0 0.1 2.4e-42 144.6 0.0 4.0 3 0 0 3 3 3 2 short chain dehydrogenase Condensation PF00668.15 KXX75016.1 - 2.9e-47 160.9 0.1 4.9e-47 160.2 0.1 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KXX75016.1 - 4.6e-44 150.7 4.3 8e-44 149.9 3.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KXX75016.1 - 7.9e-39 133.8 0.2 1.6e-38 132.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KXX75016.1 - 1.8e-34 118.8 0.0 3.8e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KXX75016.1 - 1.7e-30 105.3 0.1 3e-29 101.2 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX75016.1 - 4.7e-20 71.9 0.0 1.3e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX75016.1 - 2.2e-15 56.6 1.4 2.3e-08 34.1 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KXX75016.1 - 2.2e-13 50.2 0.0 4.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KXX75016.1 - 4.1e-13 49.4 0.0 1.2e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 KXX75016.1 - 1.2e-12 47.7 0.0 1.4e-11 44.3 0.0 2.7 3 0 0 3 3 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KXX75016.1 - 1.7e-11 44.4 0.0 4.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75016.1 - 4.6e-08 32.7 0.0 9.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX75016.1 - 1.1e-07 32.4 0.0 8.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX75016.1 - 4.5e-07 30.1 0.0 1.3e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 KXX75016.1 - 7.4e-07 28.1 0.0 3.3e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KXX75016.1 - 1.7e-06 27.3 0.0 3.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KXX75016.1 - 5.5e-05 22.2 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KXX75016.1 - 0.0039 16.8 1.0 0.014 15.0 0.7 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KXX75016.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 KXX75016.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 KXX75016.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KXX75016.1 - 0.2 10.6 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 KXX75016.1 - 0.23 10.7 0.0 0.48 9.7 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DapB_N PF01113.15 KXX75016.1 - 0.26 11.1 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_29 PF03141.11 KXX75016.1 - 1 7.5 0.0 1.6 6.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SKG6 PF08693.5 KXX75017.1 - 2.6e-05 23.4 1.0 4.8e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GCR1_C PF12550.3 KXX75018.1 - 2.5e-13 49.7 0.8 2.9e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SNO PF01174.14 KXX75019.1 - 4.7e-42 143.7 0.0 6.1e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KXX75019.1 - 2.1e-09 37.1 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KXX75019.1 - 8.6e-05 22.0 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KXX75019.1 - 0.00032 20.0 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 KXX75019.1 - 0.0017 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 KXX75019.1 - 0.057 12.8 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I HTH_13 PF11972.3 KXX75019.1 - 0.072 12.9 0.9 17 5.3 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain Peptidase_C26 PF07722.8 KXX75019.1 - 0.1 12.0 0.0 0.35 10.2 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 SR-25 PF10500.4 KXX75019.1 - 0.32 10.4 9.4 0.51 9.7 6.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OTT_1508_deam PF14441.1 KXX75020.1 - 9.8e-20 70.8 0.0 2.1e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3135 PF11333.3 KXX75020.1 - 0.15 12.2 0.4 0.91 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) FAR1 PF03101.10 KXX75021.1 - 2.5e-08 34.3 0.3 2.5e-08 34.3 0.2 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain OmpH PF03938.9 KXX75021.1 - 5.2 6.9 24.6 0.45 10.4 13.8 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AFT PF08731.6 KXX75021.1 - 7.2 6.8 8.9 3.1 8.0 3.5 2.3 2 1 0 2 2 2 0 Transcription factor AFT Pkinase PF00069.20 KXX75022.1 - 0.08 12.0 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Zn_clus PF00172.13 KXX75023.1 - 1.6e-10 40.7 13.1 2.4e-10 40.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX75023.1 - 0.013 14.4 0.0 0.027 13.3 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain COX15-CtaA PF02628.10 KXX75024.1 - 8e-97 323.7 6.7 1.1e-96 323.3 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Copper-fist PF00649.13 KXX75025.1 - 2.2e-22 77.9 2.9 2.2e-22 77.9 2.0 3.7 2 2 1 3 3 3 2 Copper fist DNA binding domain TMF_DNA_bd PF12329.3 KXX75026.1 - 0.00028 20.6 6.7 0.00028 20.6 4.7 15.7 6 4 8 15 15 15 3 TATA element modulatory factor 1 DNA binding Filament PF00038.16 KXX75026.1 - 0.00065 19.2 158.4 0.15 11.5 23.8 6.1 1 1 3 5 5 5 4 Intermediate filament protein Fib_alpha PF08702.5 KXX75026.1 - 0.79 9.8 0.0 0.79 9.8 0.0 9.4 3 2 6 10 10 10 0 Fibrinogen alpha/beta chain family ApbA PF02558.11 KXX75029.1 - 1.5e-30 105.5 0.0 2.3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KXX75029.1 - 9.6e-26 90.2 0.0 2e-25 89.2 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 KXX75029.1 - 0.1 12.9 0.0 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 KXX75030.1 - 6.5e-25 87.0 5.8 1.1e-24 86.2 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX75030.1 - 3.2e-19 68.7 0.1 9.5e-19 67.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KXX75030.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 KXX75030.1 - 0.011 16.6 0.0 0.022 15.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KXX75030.1 - 0.034 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zip PF02535.17 KXX75031.1 - 6.1e-44 150.3 0.0 1.2e-43 149.3 0.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter NAD_binding_8 PF13450.1 KXX75032.1 - 1.8e-12 47.0 0.1 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX75032.1 - 0.00054 18.9 0.9 0.003 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX75032.1 - 0.01 15.5 0.8 0.17 11.6 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX75032.1 - 0.024 14.5 0.1 0.15 11.9 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX75032.1 - 0.03 12.9 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KXX75032.1 - 0.048 12.5 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2834 PF11196.3 KXX75033.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2834) DNA_methylase PF00145.12 KXX75034.1 - 3.7e-34 118.3 0.0 8.3e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 KXX75034.1 - 3.5e-07 29.9 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 BAH domain Methyltransf_25 PF13649.1 KXX75035.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Drc1-Sld2 PF11719.3 KXX75037.1 - 2.8e-85 286.9 23.0 9.7e-85 285.2 16.0 1.7 1 1 0 1 1 1 1 DNA replication and checkpoint protein Upf2 PF04050.9 KXX75037.1 - 0.017 14.8 1.3 0.017 14.8 0.9 3.3 4 0 0 4 4 4 0 Up-frameshift suppressor 2 zf-RING_2 PF13639.1 KXX75038.1 - 6.4e-08 32.3 11.7 1.1e-07 31.5 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX75038.1 - 1.4e-07 31.3 8.0 2.5e-07 30.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX75038.1 - 1.7e-06 27.5 7.0 2.7e-06 26.9 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX75038.1 - 2.6e-05 23.7 7.5 4e-05 23.2 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX75038.1 - 0.00019 21.4 9.7 0.0005 20.1 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger GAGA PF09237.6 KXX75038.1 - 0.093 12.3 0.0 0.093 12.3 0.0 3.2 3 0 0 3 3 3 0 GAGA factor zf-Apc11 PF12861.2 KXX75038.1 - 0.2 11.5 3.0 0.46 10.3 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KXX75038.1 - 1.1 8.8 5.9 2 8.0 4.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KXX75038.1 - 2 8.1 8.8 3.5 7.4 6.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 KXX75038.1 - 3.7 7.1 9.0 6.4 6.3 6.2 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rpn3_C PF08375.6 KXX75039.1 - 1.1e-24 86.5 1.4 2.9e-24 85.2 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KXX75039.1 - 3.6e-20 72.2 1.2 2.2e-19 69.7 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KXX75039.1 - 0.015 15.1 0.1 0.048 13.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIID_20kDa PF03847.8 KXX75040.1 - 3.7e-18 65.5 0.0 6.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.5 KXX75042.1 - 1.5e-55 188.6 0.4 1.8e-54 185.1 0.3 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 DUF4407 PF14362.1 KXX75042.1 - 0.059 12.3 1.4 0.068 12.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 KXX75042.1 - 0.12 12.3 1.9 0.17 11.9 1.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4193 PF13834.1 KXX75042.1 - 0.16 12.1 2.3 0.28 11.3 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) V-SNARE PF05008.10 KXX75042.1 - 0.23 11.6 4.7 1.8 8.7 0.5 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4140 PF13600.1 KXX75042.1 - 3.6 8.0 6.2 1.5 9.3 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DSBA PF01323.15 KXX75043.1 - 9.6e-41 139.4 0.0 1.1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KXX75043.1 - 1.1e-05 25.4 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KXX75043.1 - 0.00079 19.1 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_2 PF13098.1 KXX75043.1 - 0.046 13.9 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain Sugar_tr PF00083.19 KXX75045.1 - 6.5e-82 275.5 18.1 7.5e-82 275.2 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75045.1 - 7.5e-27 93.9 18.1 1.1e-26 93.3 12.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX75045.1 - 0.00013 20.3 4.1 0.00043 18.5 0.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Tmemb_170 PF10190.4 KXX75045.1 - 0.076 13.0 0.1 0.076 13.0 0.1 2.4 2 1 1 3 3 3 0 Putative transmembrane protein 170 MFS_1 PF07690.11 KXX75047.1 - 8.7e-27 93.7 30.0 1.4e-26 93.0 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KXX75047.1 - 2.5e-08 33.1 0.0 4.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75047.1 - 1.3e-05 25.0 10.0 2.3e-05 24.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF-2B PF01008.12 KXX75048.1 - 3.7e-20 72.0 0.0 8.4e-20 70.9 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KXX75048.1 - 3e-11 43.0 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Nucleotid_trans PF03407.11 KXX75050.1 - 2.6e-08 33.8 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Methyltransf_2 PF00891.13 KXX75051.1 - 0.041 13.0 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Lactonase PF10282.4 KXX75053.1 - 1.3e-87 294.0 0.0 1.8e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ PF01011.16 KXX75053.1 - 0.28 10.7 2.5 66 3.3 0.1 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat HpcH_HpaI PF03328.9 KXX75054.1 - 2.1e-06 26.8 0.0 4.7e-06 25.6 0.0 1.5 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Methyltransf_23 PF13489.1 KXX75055.1 - 1.3e-19 70.5 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX75055.1 - 8.3e-15 55.0 0.0 2.1e-14 53.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX75055.1 - 3.5e-10 40.2 0.0 1.1e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75055.1 - 2e-09 37.2 0.0 2.9e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX75055.1 - 5.7e-08 33.3 0.0 8.3e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX75055.1 - 1.1e-07 31.1 0.1 1.4e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX75055.1 - 9.2e-05 22.7 0.0 0.00026 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX75055.1 - 0.00044 19.3 0.0 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 KXX75055.1 - 0.016 14.8 0.0 0.054 13.1 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.8 KXX75055.1 - 0.016 14.3 0.0 0.033 13.3 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KXX75055.1 - 0.026 13.8 0.0 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KXX75055.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MARVEL PF01284.18 KXX75056.1 - 0.0018 18.1 0.7 0.0024 17.7 0.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2162 PF09930.4 KXX75056.1 - 0.11 11.6 1.9 0.15 11.1 1.3 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) FA_desaturase PF00487.19 KXX75056.1 - 0.11 11.8 3.9 0.13 11.6 2.7 1.1 1 0 0 1 1 1 0 Fatty acid desaturase F-box PF00646.28 KXX75057.1 - 0.00027 20.4 0.1 0.00085 18.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX75057.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like PAN_4 PF14295.1 KXX75058.1 - 5.5e-06 25.9 0.3 1.2e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 PAN domain Glyco_hydro_61 PF03443.9 KXX75059.1 - 4e-50 170.6 0.3 4.6e-50 170.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrolase_2 PF07486.7 KXX75060.1 - 0.063 13.7 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 Cell Wall Hydrolase GPAT_N PF14829.1 KXX75060.1 - 0.12 12.0 0.3 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal YbfN PF13982.1 KXX75060.1 - 0.21 11.7 1.3 3.9 7.7 0.0 2.7 3 0 0 3 3 3 0 YbfN-like lipoprotein p450 PF00067.17 KXX75061.1 - 1.5e-56 191.8 0.0 2.1e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 KXX75062.1 - 0.023 15.0 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75062.1 - 0.098 12.5 0.0 0.39 10.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat GMC_oxred_N PF00732.14 KXX75063.1 - 2.4e-31 109.0 0.0 1.7e-28 99.6 0.0 3.1 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX75063.1 - 4.1e-31 108.2 0.0 6.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX75063.1 - 0.00067 19.6 0.1 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX75063.1 - 0.006 15.5 0.8 0.042 12.7 0.2 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX75063.1 - 0.024 13.0 0.0 0.038 12.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KXX75063.1 - 0.029 13.2 0.3 0.044 12.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX75063.1 - 0.036 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX75063.1 - 0.057 12.4 0.2 0.084 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 KXX75063.1 - 0.059 12.2 1.0 0.15 10.8 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 KXX75063.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Endonuc-PvuII PF09225.5 KXX75063.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease PvuII MIP PF00230.15 KXX75064.1 - 7.7e-47 159.6 12.7 9.7e-47 159.3 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Hydrolase_6 PF13344.1 KXX75065.1 - 8.8e-08 31.9 0.0 2.4e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase p450 PF00067.17 KXX75066.1 - 2e-49 168.3 0.0 2.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 KXX75067.1 - 2.3e-19 69.8 0.0 4.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX75067.1 - 1e-05 26.3 3.8 1.7e-05 25.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KXX75067.1 - 0.00042 19.4 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX75067.1 - 0.0015 18.5 0.0 0.005 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX75067.1 - 0.0021 18.2 0.3 0.013 15.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 KXX75067.1 - 0.0062 16.8 3.9 0.008 16.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX75067.1 - 0.023 14.4 0.2 0.063 13.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KXX75067.1 - 0.024 14.3 0.1 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KXX75067.1 - 0.055 12.9 0.0 0.71 9.3 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KXX75067.1 - 0.18 11.3 3.3 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.7 KXX75067.1 - 0.48 8.2 17.1 0.73 7.6 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.11 KXX75067.1 - 4.9 6.4 10.1 12 5.2 7.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 KXX75067.1 - 9.3 4.5 20.6 13 4.0 14.3 1.1 1 0 0 1 1 1 0 Daxx Family Ank_2 PF12796.2 KXX75069.1 - 1.3e-112 368.3 0.0 3.1e-18 65.8 0.0 7.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75069.1 - 1.8e-68 223.0 0.0 5.2e-08 32.3 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KXX75069.1 - 9.3e-59 194.8 0.5 1.3e-10 41.4 0.0 8.4 3 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX75069.1 - 4.9e-51 169.6 4.6 1.7e-09 37.5 0.0 10.6 2 2 10 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75069.1 - 8.9e-51 164.7 0.0 3.1e-06 26.9 0.0 13.9 12 1 1 13 13 13 12 Ankyrin repeat C6 PF01681.12 KXX75070.1 - 7.5 6.6 10.9 1.8 8.7 1.0 3.1 3 0 0 3 3 3 0 C6 domain Glyoxalase_2 PF12681.2 KXX75071.1 - 7.2e-09 36.2 0.0 8.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KXX75071.1 - 0.00036 20.5 0.0 0.00065 19.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PIP5K PF01504.13 KXX75075.1 - 6.7e-31 107.3 0.0 8.9e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Zn_clus PF00172.13 KXX75077.1 - 6.3e-09 35.6 10.1 1.1e-08 34.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX75077.1 - 7.2e-09 34.9 0.0 1.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KXX75080.1 - 2.5e-10 39.6 16.9 1.2e-09 37.3 5.7 3.4 2 1 0 3 3 3 2 Major Facilitator Superfamily Ank PF00023.25 KXX75081.1 - 1.3e-34 116.3 1.7 2.5e-08 33.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 KXX75081.1 - 2.6e-34 118.1 7.6 2.6e-34 118.1 5.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KXX75081.1 - 6e-33 113.0 0.0 7.4e-17 61.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX75081.1 - 1.4e-25 88.6 1.0 1.7e-07 31.2 0.0 5.4 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75081.1 - 9.3e-24 81.1 0.4 7.9e-08 31.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KXX75081.1 - 2e-22 79.1 3.5 2.5e-07 31.0 0.1 4.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) lci PF12197.3 KXX75081.1 - 0.13 11.9 0.5 0.29 10.7 0.4 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein DLH PF01738.13 KXX75082.1 - 2.6e-29 102.0 0.0 3.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX75082.1 - 8.8e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PALP PF00291.20 KXX75083.1 - 5.8e-62 209.6 0.2 7.3e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KXX75083.1 - 7.9e-08 31.9 0.0 1.5e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain AAA_19 PF13245.1 KXX75083.1 - 0.34 10.6 3.1 0.31 10.8 0.6 2.0 2 0 0 2 2 2 0 Part of AAA domain SRPRB PF09439.5 KXX75084.1 - 2.7e-22 78.8 0.0 5.4e-15 55.0 0.0 3.2 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KXX75084.1 - 0.00074 19.5 0.8 0.002 18.1 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KXX75084.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KXX75084.1 - 0.0049 16.1 0.0 0.45 9.7 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family Zeta_toxin PF06414.7 KXX75084.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KXX75084.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 KXX75084.1 - 0.023 14.1 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KXX75084.1 - 0.025 14.0 0.1 0.073 12.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KXX75084.1 - 0.043 13.0 0.2 0.15 11.2 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX75084.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KXX75084.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KXX75084.1 - 0.096 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Vac7 PF12751.2 KXX75084.1 - 0.098 11.4 0.1 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 AAA_5 PF07728.9 KXX75084.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 KXX75084.1 - 0.21 10.6 0.0 1.3 8.1 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RNase_P_pop3 PF08228.6 KXX75085.1 - 3.9e-12 46.2 0.0 5e-08 32.9 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 FAM101 PF15068.1 KXX75085.1 - 0.039 13.4 0.5 0.05 13.0 0.4 1.2 1 0 0 1 1 1 0 FAM101 family Pyr_redox_2 PF07992.9 KXX75086.1 - 5e-36 124.4 0.0 9.1e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX75086.1 - 8e-10 39.0 0.0 6.9e-08 32.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KXX75086.1 - 4e-05 22.8 0.0 7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox_3 PF13738.1 KXX75086.1 - 0.0047 17.0 0.0 0.38 10.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Anillin PF08174.6 KXX75087.1 - 7.6e-34 116.7 0.0 3e-33 114.8 0.0 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KXX75087.1 - 7.4e-07 29.3 0.0 2.6e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF4602 PF15375.1 KXX75089.1 - 0.00013 22.0 7.4 0.0032 17.5 3.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4602) CENP-B_dimeris PF09026.5 KXX75089.1 - 0.028 14.6 5.0 0.071 13.3 3.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 KXX75089.1 - 0.2 9.5 12.1 0.28 9.0 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family His_biosynth PF00977.16 KXX75090.1 - 2.1e-34 118.7 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KXX75090.1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Baculo_PEP_C PF04513.7 KXX75092.1 - 0.071 12.9 3.9 0.11 12.3 2.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 KXX75092.1 - 0.079 10.4 1.1 0.094 10.2 0.8 1.0 1 0 0 1 1 1 0 Prominin Med11 PF10280.4 KXX75092.1 - 0.35 10.9 2.3 0.69 9.9 0.2 2.0 1 1 1 2 2 2 0 Mediator complex protein SIN1 PF05422.7 KXX75093.1 - 1.2e-40 139.5 1.4 6.2e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KXX75093.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG RBD PF02196.10 KXX75093.1 - 0.15 11.8 0.1 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain PRCC PF10253.4 KXX75094.1 - 1e-34 120.8 2.2 1e-34 120.8 1.5 2.9 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting UCH PF00443.24 KXX75096.1 - 3.6e-41 141.0 0.6 6e-41 140.3 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KXX75096.1 - 1e-30 106.5 0.0 2e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KXX75096.1 - 5.9e-16 58.7 0.3 1.1e-15 57.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sld5 PF05916.6 KXX75097.1 - 8.4e-10 38.9 0.3 1.6e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein GBS_Bsp-like PF08481.5 KXX75098.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 GBS Bsp-like repeat DUF3693 PF12472.3 KXX75098.1 - 0.1 12.2 0.4 0.42 10.2 0.3 2.1 1 0 0 1 1 1 0 Phage related protein Aldolase_II PF00596.16 KXX75099.1 - 9.8e-41 139.3 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldedh PF00171.17 KXX75101.1 - 4.5e-133 443.9 0.2 5.5e-133 443.6 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 KXX75102.1 - 3.2e-163 542.6 21.2 5.2e-163 541.9 14.7 1.3 1 0 0 1 1 1 1 Calreticulin family Aminotran_5 PF00266.14 KXX75103.1 - 4.7e-22 78.2 0.0 2.6e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 KXX75103.1 - 1.1e-21 76.7 0.0 1.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KXX75103.1 - 3.8e-21 74.9 0.0 7e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain AAA_22 PF13401.1 KXX75104.1 - 2.2e-13 50.4 0.1 6.2e-13 49.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KXX75104.1 - 8.6e-13 48.6 0.9 6.4e-12 45.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KXX75104.1 - 3.3e-09 37.0 0.0 8.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KXX75104.1 - 0.00024 21.0 0.0 0.00055 19.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KXX75104.1 - 0.0016 18.2 0.0 0.0065 16.2 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KXX75104.1 - 0.0026 17.6 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX75104.1 - 0.003 17.2 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KXX75104.1 - 0.0037 16.9 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KXX75104.1 - 0.0045 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KXX75104.1 - 0.0048 15.7 0.0 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 KXX75104.1 - 0.012 15.1 0.1 0.05 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain Cdc6_C PF09079.6 KXX75104.1 - 0.014 15.1 0.0 0.05 13.3 0.0 2.0 1 0 0 1 1 1 0 CDC6, C terminal RNA_helicase PF00910.17 KXX75104.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 KXX75104.1 - 0.031 14.7 0.3 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 KXX75104.1 - 0.037 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase DAP3 PF10236.4 KXX75104.1 - 0.041 12.8 0.5 0.29 10.0 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 KAP_NTPase PF07693.9 KXX75104.1 - 0.042 12.8 0.0 0.12 11.3 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain AAA_32 PF13654.1 KXX75104.1 - 0.044 12.4 0.0 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX75104.1 - 0.055 14.2 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.3 KXX75104.1 - 0.11 11.1 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF815 PF05673.8 KXX75104.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KXX75104.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_35 PF14516.1 KXX75104.1 - 0.13 10.9 0.0 0.3 9.6 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Fungal_trans PF04082.13 KXX75105.1 - 4.7e-13 48.6 0.1 7.8e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75105.1 - 9e-09 35.1 8.3 1.7e-08 34.2 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBOAT_2 PF13813.1 KXX75106.1 - 3.5e-14 52.6 1.9 3.1e-13 49.6 0.1 2.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family URO-D PF01208.12 KXX75108.1 - 9.3e-123 409.5 0.0 1.1e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FR47 PF08445.5 KXX75109.1 - 0.00046 19.8 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3602 PF12223.3 KXX75110.1 - 4.4e-16 59.0 15.0 5.6e-14 52.2 1.9 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GlyL_C PF12524.3 KXX75110.1 - 0.11 12.4 0.5 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Velvet PF11754.3 KXX75111.1 - 1.5e-74 250.0 0.0 2.3e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Velvet factor CTD PF12815.2 KXX75111.1 - 0.02 15.3 6.8 0.02 15.3 4.7 2.3 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Beta-lactamase PF00144.19 KXX75112.1 - 3.6e-47 161.0 1.6 5e-47 160.5 1.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KXX75112.1 - 0.006 15.8 0.1 0.011 14.9 0.1 1.4 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PH_10 PF15411.1 KXX75114.1 - 1.2e-45 154.4 0.2 1.9e-45 153.7 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KXX75114.1 - 1.3e-33 114.9 0.0 2.6e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 KXX75114.1 - 1.9e-24 86.5 0.1 3.3e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 KXX75114.1 - 2e-10 40.1 0.0 4.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Snf7 PF03357.16 KXX75119.1 - 7.3e-44 149.1 13.2 9.6e-44 148.7 9.1 1.1 1 0 0 1 1 1 1 Snf7 TBPIP PF07106.8 KXX75119.1 - 0.0089 15.5 11.8 1.1 8.8 1.2 3.2 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4201 PF13870.1 KXX75119.1 - 0.0098 15.3 8.0 0.034 13.5 5.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) BLOC1_2 PF10046.4 KXX75119.1 - 0.01 15.9 7.2 0.17 12.0 2.1 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 KXX75119.1 - 0.02 14.8 10.0 0.017 15.0 5.7 1.8 1 1 1 2 2 2 0 FlxA-like protein Reo_sigmaC PF04582.7 KXX75119.1 - 0.05 12.7 4.8 0.44 9.6 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KXX75119.1 - 0.096 12.9 6.9 12 6.2 0.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein NuA4 PF09340.5 KXX75119.1 - 0.12 11.9 0.9 0.29 10.8 0.6 1.7 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 CENP-F_leu_zip PF10473.4 KXX75119.1 - 0.13 12.1 14.8 2.8 7.7 9.0 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KXX75119.1 - 0.14 12.0 5.7 0.062 13.1 0.9 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1395 PF07160.7 KXX75119.1 - 0.18 11.3 5.6 0.3 10.5 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) DUF2205 PF10224.4 KXX75119.1 - 0.21 11.1 6.1 0.68 9.5 1.8 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF4140 PF13600.1 KXX75119.1 - 0.33 11.4 0.0 0.33 11.4 0.0 3.7 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) FliD_C PF07195.7 KXX75119.1 - 0.41 9.8 0.1 0.41 9.8 0.0 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Mnd1 PF03962.10 KXX75119.1 - 0.45 10.1 10.6 0.84 9.2 5.8 2.2 1 1 1 2 2 2 0 Mnd1 family OmpH PF03938.9 KXX75119.1 - 0.87 9.5 13.6 0.2 11.5 5.3 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KXX75119.1 - 1 8.9 13.2 2.4 7.7 3.5 2.6 1 1 1 2 2 2 0 IncA protein TACC PF05010.9 KXX75119.1 - 1.1 8.9 11.8 2.9 7.5 8.2 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Mod_r PF07200.8 KXX75119.1 - 1.4 8.8 11.7 3.8 7.4 7.7 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.1 KXX75119.1 - 1.7 7.5 7.2 2.6 6.9 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 KXX75119.1 - 2.6 7.8 7.2 0.52 10.1 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Baculo_PEP_C PF04513.7 KXX75119.1 - 3.3 7.5 7.7 7.3 6.4 0.1 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 KXX75119.1 - 8 6.4 6.3 10 6.0 0.0 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.8 KXX75120.1 - 0.0021 17.9 4.1 0.0048 16.8 2.8 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Ank_4 PF13637.1 KXX75120.1 - 0.0097 16.4 0.0 0.25 11.9 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Lectin_N PF03954.9 KXX75120.1 - 0.01 15.2 3.6 0.063 12.6 1.5 2.5 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Ank_2 PF12796.2 KXX75120.1 - 0.012 15.9 0.1 0.038 14.3 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF1512 PF07431.7 KXX75120.1 - 0.021 13.6 0.1 0.05 12.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1512) Ank_3 PF13606.1 KXX75120.1 - 0.09 13.0 0.1 0.5 10.7 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeat WD40 PF00400.27 KXX75121.1 - 9.1e-38 126.8 12.4 2.7e-06 27.0 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KXX75121.1 - 4.4e-14 51.9 2.8 2.6e-13 49.4 0.7 2.5 1 1 1 2 2 2 1 F-box-like Nup160 PF11715.3 KXX75121.1 - 1.8e-07 29.6 0.9 0.00028 19.1 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 F-box PF00646.28 KXX75121.1 - 4e-07 29.5 0.6 1.8e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain MgtE_N PF03448.12 KXX75121.1 - 0.03 14.6 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain NmrA PF05368.8 KXX75122.1 - 1.8e-33 115.7 0.0 2.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX75122.1 - 7.8e-17 61.8 0.1 1e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX75122.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KXX75122.1 - 0.0044 17.2 0.1 0.0076 16.5 0.1 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KXX75122.1 - 0.014 15.1 0.1 0.22 11.1 0.0 2.6 3 0 0 3 3 3 0 KR domain His_biosynth PF00977.16 KXX75122.1 - 0.024 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein adh_short PF00106.20 KXX75122.1 - 0.036 13.9 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 KXX75122.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 KXX75122.1 - 0.11 11.1 0.1 1.2 7.7 0.1 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BUD22 PF09073.5 KXX75123.1 - 0.45 9.5 6.5 0.49 9.4 4.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KXX75123.1 - 2 6.2 5.5 1.8 6.3 3.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KXX75123.1 - 3.1 6.9 6.1 3 7.0 4.3 1.1 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 KXX75123.1 - 5.5 6.9 8.8 8 6.4 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CEP19 PF14933.1 KXX75124.1 - 0.034 14.4 0.7 0.14 12.4 0.1 2.3 1 1 1 2 2 2 0 CEP19-like protein Fungal_trans PF04082.13 KXX75125.1 - 8.3e-62 208.3 0.1 1.1e-61 207.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KXX75125.1 - 2.7e-06 27.3 9.3 0.00018 21.6 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX75125.1 - 5.2e-06 26.4 10.5 0.00045 20.3 0.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX75125.1 - 0.36 11.1 11.6 0.25 11.7 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.1 KXX75126.1 - 7.7e-13 48.0 0.5 3e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Ribosomal_60s PF00428.14 KXX75127.1 - 5.7e-05 23.4 19.5 0.0029 17.9 3.3 2.4 2 0 0 2 2 2 2 60s Acidic ribosomal protein F-box PF00646.28 KXX75127.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nop14 PF04147.7 KXX75127.1 - 0.0025 15.8 10.1 0.0042 15.1 7.0 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 KXX75127.1 - 0.0032 16.8 6.1 0.0032 16.8 4.2 1.9 2 0 0 2 2 2 1 SDA1 DUF4611 PF15387.1 KXX75127.1 - 0.0035 17.4 12.0 0.38 10.9 1.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KXX75127.1 - 0.0064 16.0 22.4 0.03 13.8 0.1 2.7 3 0 0 3 3 3 2 Nucleoplasmin Myc_N PF01056.13 KXX75127.1 - 0.022 13.9 9.4 0.82 8.7 3.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region F-box-like PF12937.2 KXX75127.1 - 0.039 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Sigma70_ner PF04546.8 KXX75127.1 - 0.05 13.2 22.7 0.037 13.6 2.2 2.5 3 0 0 3 3 2 0 Sigma-70, non-essential region CDC45 PF02724.9 KXX75127.1 - 0.096 10.7 7.9 0.04 11.9 0.2 2.3 2 0 0 2 2 2 0 CDC45-like protein PepSY_2 PF13670.1 KXX75127.1 - 0.19 11.6 4.9 0.45 10.4 3.4 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain YL1 PF05764.8 KXX75127.1 - 0.35 10.4 11.3 0.71 9.4 7.9 1.4 1 1 0 1 1 1 0 YL1 nuclear protein NESP55 PF06390.7 KXX75127.1 - 0.45 9.8 11.7 0.17 11.2 3.9 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) RXT2_N PF08595.6 KXX75127.1 - 1 9.1 13.5 0.2 11.4 0.6 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3245 PF11595.3 KXX75127.1 - 1.6 8.9 10.9 3.6 7.8 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Cnd2 PF05786.9 KXX75127.1 - 1.7 7.0 10.2 1.3 7.4 3.3 2.2 2 0 0 2 2 2 0 Condensin complex subunit 2 FAM176 PF14851.1 KXX75127.1 - 3 7.5 9.1 24 4.5 0.1 2.3 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.6 KXX75127.1 - 3.4 7.3 7.6 7 6.2 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Daxx PF03344.10 KXX75127.1 - 3.7 5.9 12.9 1.1 7.6 3.8 2.1 2 0 0 2 2 2 0 Daxx Family PBP1_TM PF14812.1 KXX75127.1 - 5.1 7.4 30.9 0.41 10.9 5.3 3.2 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 KXX75127.1 - 5.8 6.1 18.3 4.1 6.5 7.9 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FimP PF09766.4 KXX75127.1 - 7.3 5.5 6.7 18 4.2 0.1 2.1 2 0 0 2 2 2 0 Fms-interacting protein MFS_1 PF07690.11 KXX75128.1 - 1.6e-36 125.7 57.5 3.6e-36 124.6 37.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX75128.1 - 1.3e-13 50.3 33.9 1.2e-11 43.8 5.8 3.3 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KXX75128.1 - 1.3e-09 36.8 19.2 4.5e-09 35.0 13.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CTDII PF01556.13 KXX75129.1 - 5.7e-31 106.2 1.0 4.7e-23 80.8 0.1 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 KXX75129.1 - 1e-24 85.9 1.6 1.9e-24 85.1 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KXX75129.1 - 8.4e-11 41.7 19.2 1.6e-10 40.8 13.3 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF2418 PF10332.4 KXX75130.1 - 7.3e-35 119.2 0.6 1.3e-34 118.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Pyridox_oxase_2 PF12766.2 KXX75131.1 - 1.1e-19 70.6 0.0 1.9e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4510 PF14971.1 KXX75131.1 - 0.0037 17.4 0.6 0.58 10.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4510) E1_DerP2_DerF2 PF02221.10 KXX75132.1 - 1.6e-26 93.1 0.8 1.9e-26 92.8 0.6 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KXX75132.1 - 0.0026 17.8 0.4 0.013 15.5 0.1 2.1 1 1 0 1 1 1 1 ML-like domain CopC PF04234.7 KXX75132.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 CopC domain ATP-synt_F PF01990.12 KXX75133.1 - 1.8e-27 95.5 0.0 2.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF342 PF03961.8 KXX75134.1 - 0.00085 17.8 10.0 0.00085 17.8 6.9 3.7 2 1 2 4 4 4 2 Protein of unknown function (DUF342) Hemagglutinin PF00509.13 KXX75134.1 - 0.02 13.0 2.5 0.048 11.8 1.7 1.5 1 0 0 1 1 1 0 Haemagglutinin Claudin_3 PF06653.6 KXX75136.1 - 0.26 11.0 3.4 2.6 7.7 0.1 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like RNA_pol_Rpb5_C PF01191.14 KXX75137.1 - 1.3e-35 120.8 0.2 2.4e-35 119.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KXX75137.1 - 1.5e-31 108.6 0.0 2.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KXX75137.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease AAA_3 PF07726.6 KXX75137.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PHD PF00628.24 KXX75138.1 - 1.3e-07 31.1 8.6 2.5e-07 30.2 6.0 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 KXX75138.1 - 4.2e-07 30.3 0.0 4.2e-07 30.3 0.0 2.6 3 1 0 3 3 3 1 SET domain Fungal_trans PF04082.13 KXX75139.1 - 3.1e-18 65.5 0.0 4.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75139.1 - 6.2e-09 35.6 11.3 1e-08 34.9 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B_N_2 PF13631.1 KXX75141.1 - 0.023 14.5 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF912 PF06024.7 KXX75141.1 - 0.027 14.4 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Beta-lactamase PF00144.19 KXX75141.1 - 0.089 11.7 0.4 0.13 11.2 0.1 1.3 1 1 0 1 1 1 0 Beta-lactamase Chorismate_synt PF01264.16 KXX75142.1 - 3.8e-128 426.8 0.0 6.9e-128 425.9 0.0 1.4 1 1 0 1 1 1 1 Chorismate synthase AA_permease_2 PF13520.1 KXX75143.1 - 7.2e-40 136.8 26.9 2.6e-39 134.9 18.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX75143.1 - 2e-06 26.4 14.4 5.5e-06 24.9 9.9 1.7 1 0 0 1 1 1 1 Amino acid permease Exo70 PF03081.10 KXX75144.1 - 0.094 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit ApoC-I PF04691.7 KXX75144.1 - 0.2 11.3 1.4 0.45 10.2 0.3 2.1 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) MazG-like PF12643.2 KXX75145.1 - 4.6e-08 32.8 0.0 5.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 MazG-like family MazG PF03819.12 KXX75145.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF550 PF04447.7 KXX75145.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF550) Ank_2 PF12796.2 KXX75146.1 - 4e-108 353.9 13.7 9.5e-23 80.3 0.5 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75146.1 - 1.8e-86 279.9 11.2 1.5e-09 37.1 0.0 12.8 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KXX75146.1 - 1.7e-78 257.7 14.3 7e-11 42.3 0.1 9.6 2 1 10 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75146.1 - 2.8e-65 209.6 0.8 2.4e-06 27.2 0.0 13.2 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.1 KXX75146.1 - 4.9e-55 182.3 13.8 3e-10 39.9 0.2 10.9 2 2 9 11 11 11 9 Ankyrin repeats (many copies) INTS5_C PF14838.1 KXX75146.1 - 0.19 9.9 0.1 0.58 8.3 0.0 1.7 3 0 0 3 3 3 0 Integrator complex subunit 5 C-terminus DUF1843 PF08898.5 KXX75146.1 - 1.5 8.9 12.4 4.6 7.3 0.0 4.9 6 1 1 7 7 7 0 Domain of unknown function (DUF1843) HATPase_c_3 PF13589.1 KXX75147.1 - 4.7e-16 58.6 0.0 8.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KXX75147.1 - 2.3e-07 30.4 0.0 5.8e-06 25.9 0.0 2.8 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KXX75147.1 - 0.00051 19.7 0.0 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Clathrin PF00637.15 KXX75148.1 - 5.7e-24 84.3 5.8 1.2e-22 80.0 1.5 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 KXX75148.1 - 1.4e-20 72.8 0.5 5.3e-20 71.0 0.2 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 KXX75148.1 - 6.8e-06 25.8 6.1 1.5e-05 24.6 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX75148.1 - 0.00013 21.6 5.3 0.00026 20.6 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX75148.1 - 0.00053 19.5 4.5 0.0012 18.4 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX75148.1 - 0.00069 19.6 3.3 0.0019 18.2 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 KXX75148.1 - 0.0015 17.9 1.6 0.0037 16.7 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TPR_15 PF13429.1 KXX75148.1 - 0.002 17.2 1.3 0.02 13.9 1.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-Apc11 PF12861.2 KXX75148.1 - 0.0022 17.8 1.2 0.0058 16.4 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_11 PF13414.1 KXX75148.1 - 0.0024 17.4 0.1 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 TPR repeat zf-RING_6 PF14835.1 KXX75148.1 - 0.0042 16.8 0.4 0.0094 15.7 0.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KXX75148.1 - 0.0078 16.2 4.6 0.0078 16.2 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.1 KXX75148.1 - 0.013 15.8 1.8 1.6 9.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75148.1 - 0.014 15.9 0.2 23 5.9 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75148.1 - 0.024 14.5 1.9 0.079 12.9 0.1 2.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX75148.1 - 0.029 14.3 4.8 0.47 10.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75148.1 - 0.034 13.9 4.5 0.086 12.6 0.3 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4241 PF14025.1 KXX75148.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4241) zf-C3HC4_3 PF13920.1 KXX75148.1 - 0.26 10.9 3.6 0.52 10.0 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX75148.1 - 0.77 9.6 4.7 1.6 8.6 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_1 PF00515.23 KXX75148.1 - 2.6 7.8 6.0 1.2 8.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 KXX75149.1 - 1.1e-13 51.2 0.0 2.4e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HET PF06985.6 KXX75150.1 - 0.24 11.5 3.7 0.1 12.7 0.8 1.7 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) AAA PF00004.24 KXX75151.1 - 2e-36 125.0 0.0 4.3e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX75151.1 - 4.7e-07 29.9 0.6 6.2e-06 26.3 0.1 2.6 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KXX75151.1 - 3.9e-06 27.0 0.1 0.00022 21.3 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 KXX75151.1 - 0.00031 20.6 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75151.1 - 0.00038 21.2 0.2 0.0012 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX75151.1 - 0.00047 19.8 0.4 0.0012 18.5 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KXX75151.1 - 0.0012 17.9 0.1 0.0048 15.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KXX75151.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX75151.1 - 0.0017 18.0 0.1 0.0043 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KXX75151.1 - 0.0026 17.2 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KXX75151.1 - 0.0042 16.5 0.1 0.5 9.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 KXX75151.1 - 0.0055 16.8 0.0 0.0091 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 KXX75151.1 - 0.0061 15.5 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 KXX75151.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KXX75151.1 - 0.02 14.9 0.0 0.057 13.4 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain DUF853 PF05872.7 KXX75151.1 - 0.02 13.2 0.0 0.49 8.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.1 KXX75151.1 - 0.021 14.7 0.1 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KXX75151.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KXX75151.1 - 0.023 14.2 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KXX75151.1 - 0.026 14.0 0.1 0.8 9.1 0.0 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 KXX75151.1 - 0.03 13.9 0.1 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX75151.1 - 0.033 13.3 0.1 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KXX75151.1 - 0.081 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KXX75151.1 - 0.093 12.4 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 KXX75151.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NTPase MCM PF00493.18 KXX75151.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 KXX75151.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.8 KXX75151.1 - 0.14 10.7 0.5 0.25 10.0 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus Glyco_hydro_63 PF03200.11 KXX75152.1 - 1.6e-249 830.0 0.0 1.6e-248 826.7 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KXX75152.1 - 0.0023 16.6 0.0 0.0037 15.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KXX75152.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase bZIP_1 PF00170.16 KXX75153.1 - 0.015 15.2 6.8 0.03 14.2 4.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KXX75153.1 - 0.021 14.6 9.6 0.021 14.6 6.7 1.6 2 0 0 2 2 2 0 Basic region leucine zipper CytochromB561_N PF09786.4 KXX75153.1 - 0.3 9.4 5.1 0.36 9.2 3.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hex_IIIa PF02455.11 KXX75153.1 - 2.5 6.6 9.2 3.6 6.1 6.4 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF2514 PF10721.4 KXX75153.1 - 3.8 7.1 9.0 6.3 6.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) IGR PF09597.5 KXX75154.1 - 9.2e-24 83.1 0.1 1.4e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 KXX75154.1 - 0.0022 18.1 0.0 0.044 13.9 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 KXX75155.1 - 3.3e-55 187.0 0.0 6.2e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KXX75155.1 - 5.1e-09 35.8 10.6 1.1e-08 34.7 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KXX75155.1 - 8.9e-08 31.6 8.9 1.8e-07 30.6 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX75155.1 - 1.3e-07 31.1 9.7 2.5e-07 30.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX75155.1 - 2e-07 30.8 10.8 4.5e-07 29.7 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX75155.1 - 4.7e-06 26.2 9.4 9.3e-06 25.2 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KXX75155.1 - 8.7e-06 25.7 5.6 2.7e-05 24.1 3.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 KXX75155.1 - 0.015 15.0 1.6 0.033 13.9 1.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 KXX75155.1 - 0.028 13.9 5.9 0.068 12.7 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KXX75155.1 - 0.033 13.9 5.1 0.031 13.9 2.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Helicase_C PF00271.26 KXX75155.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 KXX75155.1 - 0.08 12.8 8.3 0.19 11.5 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KXX75155.1 - 0.77 9.2 7.1 2.7 7.5 4.9 1.9 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.2 KXX75155.1 - 0.91 9.3 5.4 2.6 7.9 3.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 KXX75155.1 - 1.8 8.1 9.1 0.5 9.9 3.7 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Sec10 PF07393.6 KXX75156.1 - 1.6e-176 588.6 0.0 2e-176 588.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KXX75156.1 - 2.6e-07 30.2 0.3 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KXX75156.1 - 3.5e-06 26.5 0.0 8.5e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 KXX75157.1 - 1.9e-63 214.0 0.0 3.7e-63 213.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75157.1 - 9.3e-31 106.8 0.0 1.2e-30 106.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX75157.1 - 0.00029 19.8 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.4 KXX75158.1 - 6.7e-42 143.3 13.7 7.8e-42 143.1 9.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Med25_NR-box PF11244.3 KXX75158.1 - 0.31 11.5 2.8 0.46 10.9 1.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing HlyIII PF03006.15 KXX75158.1 - 4.1 6.7 16.2 1.7 8.0 7.7 2.3 1 1 1 2 2 2 0 Haemolysin-III related DUF4131 PF13567.1 KXX75158.1 - 5.9 6.2 21.1 2.8 7.3 1.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) NfeD PF01957.13 KXX75158.1 - 7 6.7 10.7 2.6 8.1 2.1 2.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3812 PF12757.2 KXX75159.1 - 1.4e-35 121.9 16.9 1.4e-35 121.9 11.7 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) Ribosomal_L4 PF00573.17 KXX75160.1 - 1.7e-42 145.0 1.1 2.2e-42 144.6 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KXX75160.1 - 1.1e-28 98.9 0.5 1.1e-28 98.9 0.4 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_28 PF00295.12 KXX75161.1 - 6.6e-41 140.3 7.1 9.6e-41 139.7 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RabGAP-TBC PF00566.13 KXX75162.1 - 3.4e-33 114.9 4.5 1.1e-32 113.2 3.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KXX75162.1 - 8.3e-10 38.3 0.0 0.00022 20.5 0.0 3.9 3 1 1 4 4 4 3 Domain of unknown function (DUF3548) DUF4428 PF14471.1 KXX75163.1 - 0.12 12.1 0.0 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Pkinase PF00069.20 KXX75164.1 - 1.1e-60 204.9 0.0 1.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75164.1 - 2.8e-34 118.3 0.0 4e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX75164.1 - 2.4e-08 33.3 0.0 3.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KXX75164.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Amidohydro_2 PF04909.9 KXX75165.1 - 1.4e-28 100.2 0.2 2.9e-28 99.2 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase Asparaginase PF00710.15 KXX75165.1 - 0.12 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Asparaginase DEAD PF00270.24 KXX75166.1 - 1.1e-41 142.0 0.0 4.5e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX75166.1 - 4.7e-27 93.6 0.1 1e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KXX75166.1 - 4.6e-05 22.3 0.0 7.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain FA_hydroxylase PF04116.8 KXX75167.1 - 9.7e-15 54.9 14.5 9.7e-15 54.9 10.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4519 PF15012.1 KXX75167.1 - 0.079 12.8 0.5 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Dor1 PF04124.7 KXX75167.1 - 0.11 10.9 0.1 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family Septin PF00735.13 KXX75169.1 - 5.7e-16 58.3 0.0 9.1e-15 54.4 0.0 2.2 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KXX75169.1 - 1.1e-05 25.3 0.0 3.3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX75169.1 - 0.00044 20.7 0.4 0.0017 18.8 0.1 2.1 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 KXX75169.1 - 0.0026 17.9 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KXX75169.1 - 0.0028 16.8 0.1 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX75169.1 - 0.0089 16.0 0.7 0.019 14.9 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KXX75169.1 - 0.01 15.3 0.3 0.037 13.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KXX75169.1 - 0.011 15.2 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 KXX75169.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX75169.1 - 0.022 14.9 0.1 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KXX75169.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KXX75169.1 - 0.03 14.5 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 KXX75169.1 - 0.04 12.8 0.4 0.093 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.18 KXX75169.1 - 0.049 12.4 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Gtr1_RagA PF04670.7 KXX75169.1 - 0.065 12.3 0.3 3.6 6.6 0.0 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 KXX75169.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 KXX75169.1 - 0.087 12.4 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TIP49 PF06068.8 KXX75169.1 - 0.09 11.4 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 KXX75169.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KXX75169.1 - 0.14 11.9 0.1 1.5 8.6 0.1 2.3 1 1 0 1 1 1 0 Dynamin family MobB PF03205.9 KXX75169.1 - 0.15 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 KXX75169.1 - 0.15 11.4 0.0 0.65 9.4 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.21 KXX75169.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 KXX75169.1 - 0.18 12.5 0.1 0.42 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 KXX75170.1 - 0.0038 16.8 11.2 0.0062 16.1 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KXX75170.1 - 0.028 14.2 6.1 0.044 13.5 4.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KXX75170.1 - 1.6 8.5 12.7 2.5 7.9 8.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PPR_2 PF13041.1 KXX75172.1 - 2.8e-28 97.6 0.0 3.7e-07 30.0 0.0 7.0 5 1 1 6 6 6 6 PPR repeat family PPR_3 PF13812.1 KXX75172.1 - 2.8e-21 73.9 0.3 0.0033 17.5 0.0 8.4 8 0 0 8 8 8 6 Pentatricopeptide repeat domain PPR PF01535.15 KXX75172.1 - 9.2e-18 62.9 0.0 0.011 15.6 0.0 6.5 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 KXX75172.1 - 1.9e-12 46.4 0.4 0.0044 16.4 0.0 5.5 5 0 0 5 5 5 3 PPR repeat ECSIT PF06239.6 KXX75172.1 - 0.21 10.4 0.0 7.9 5.2 0.0 2.8 2 1 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway DAGK_cat PF00781.19 KXX75173.1 - 0.088 12.2 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DnaJ PF00226.26 KXX75174.1 - 2.2e-12 46.5 0.4 7.5e-12 44.8 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain FlxA PF14282.1 KXX75174.1 - 0.12 12.3 0.3 0.12 12.3 0.2 3.1 3 0 0 3 3 3 0 FlxA-like protein ARGLU PF15346.1 KXX75174.1 - 2.4 7.9 36.3 4.1 7.1 3.8 3.4 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 DIOX_N PF14226.1 KXX75175.1 - 4.4e-21 75.5 0.0 8.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX75175.1 - 2.9e-16 59.5 0.0 4.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YL1 PF05764.8 KXX75176.1 - 0.046 13.3 22.8 0.039 13.5 2.5 2.2 2 0 0 2 2 2 0 YL1 nuclear protein GCV_T PF01571.16 KXX75177.1 - 6.3e-15 55.1 0.0 1.3e-14 54.0 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KXX75177.1 - 0.0079 16.2 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain OAR PF03826.12 KXX75179.1 - 6.6 6.3 5.7 5.1 6.7 1.5 2.2 2 0 0 2 2 2 0 OAR domain Macoilin PF09726.4 KXX75181.1 - 0.39 8.9 3.3 0.5 8.5 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein NfeD PF01957.13 KXX75181.1 - 0.55 10.3 4.0 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding dCMP_cyt_deam_1 PF00383.17 KXX75182.1 - 4.3e-09 35.9 0.0 6.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KXX75182.1 - 0.084 12.7 0.5 1.7 8.4 0.3 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase TB2_DP1_HVA22 PF03134.14 KXX75183.1 - 1.8e-30 104.5 8.4 2.5e-30 104.0 5.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Serglycin PF04360.7 KXX75183.1 - 0.018 14.7 0.9 0.018 14.7 0.6 2.1 2 0 0 2 2 2 0 Serglycin Period_C PF12114.3 KXX75183.1 - 4 7.0 6.1 5.6 6.5 4.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Mgm101p PF06420.7 KXX75184.1 - 9.6e-92 304.9 0.0 1.2e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 KXX75185.1 - 5.4e-142 472.9 0.0 6.5e-142 472.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KXX75185.1 - 2.3e-20 72.8 0.0 4.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HEAT_2 PF13646.1 KXX75186.1 - 0.034 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 HEAT repeats Conotoxin PF02950.12 KXX75188.1 - 0.0012 19.5 0.8 0.0014 19.4 0.5 1.3 1 0 0 1 1 1 1 Conotoxin Agouti PF05039.7 KXX75188.1 - 0.031 14.5 1.9 0.034 14.4 1.3 1.1 1 0 0 1 1 1 0 Agouti protein Omega-toxin PF06357.6 KXX75188.1 - 0.04 13.4 5.2 0.057 13.0 3.6 1.3 1 0 0 1 1 1 0 Omega-atracotoxin UPF0506 PF11703.3 KXX75188.1 - 0.059 13.3 5.1 0.083 12.8 3.5 1.3 1 0 0 1 1 1 0 UPF0506 Prefoldin_2 PF01920.15 KXX75189.1 - 4.8e-21 74.5 0.4 5.8e-21 74.2 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF16 PF01519.11 KXX75189.1 - 0.0066 16.6 3.1 0.016 15.4 2.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF16 TBPIP PF07106.8 KXX75189.1 - 0.019 14.5 0.8 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 KXX75189.1 - 0.031 14.0 2.0 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.1 KXX75189.1 - 0.042 13.8 4.1 0.064 13.2 0.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RtcR PF06956.6 KXX75189.1 - 0.051 12.8 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Jnk-SapK_ap_N PF09744.4 KXX75189.1 - 0.069 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlxA PF14282.1 KXX75189.1 - 0.58 10.1 8.1 2.1 8.3 1.4 2.1 2 0 0 2 2 2 0 FlxA-like protein Tropomyosin PF00261.15 KXX75189.1 - 1.1 8.2 6.8 0.35 9.9 0.4 2.0 2 0 0 2 2 2 0 Tropomyosin Ank_5 PF13857.1 KXX75190.1 - 4.4e-42 141.1 7.8 2.9e-10 40.0 0.3 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX75190.1 - 1e-40 137.9 2.7 7.1e-14 51.9 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75190.1 - 2e-37 125.1 5.9 1e-06 28.2 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KXX75190.1 - 3.5e-34 116.5 4.7 4e-11 43.1 0.1 4.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75190.1 - 1.1e-31 105.7 1.7 0.00012 22.0 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Phage_tail_X PF05489.7 KXX75190.1 - 0.039 13.4 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X WD40 PF00400.27 KXX75191.1 - 8.1e-51 168.1 16.6 2.4e-09 36.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KXX75191.1 - 0.049 11.7 4.6 13 3.7 0.0 4.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Bac_transf PF02397.11 KXX75191.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial sugar transferase Ceramidase PF05875.7 KXX75192.1 - 3.3e-92 308.3 15.8 3.8e-92 308.1 11.0 1.0 1 0 0 1 1 1 1 Ceramidase DUF1691 PF07950.6 KXX75192.1 - 0.62 10.0 5.1 1.1 9.2 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) EamA PF00892.15 KXX75192.1 - 4.9 7.2 14.4 0.33 10.9 4.1 2.7 2 2 0 2 2 2 0 EamA-like transporter family TMF_TATA_bd PF12325.3 KXX75193.1 - 7e-40 135.5 9.9 7e-40 135.5 6.9 6.5 2 1 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KXX75193.1 - 4.3e-19 68.0 17.0 4.3e-19 68.0 11.8 8.9 4 3 5 9 9 9 4 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KXX75193.1 - 0.00049 19.9 18.8 0.00049 19.9 13.0 5.7 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KXX75193.1 - 0.00096 19.0 16.9 0.00096 19.0 11.7 5.4 3 1 2 5 5 5 2 Tropomyosin like Reo_sigmaC PF04582.7 KXX75193.1 - 0.033 13.3 26.3 0.27 10.3 0.8 4.9 3 1 1 5 5 5 0 Reovirus sigma C capsid protein Filament PF00038.16 KXX75193.1 - 1.1 8.6 79.1 0.3 10.5 12.2 3.6 2 1 1 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 KXX75193.1 - 1.2 7.5 58.4 0.026 13.0 17.1 3.2 2 1 1 3 3 3 0 AAA domain MtrG PF04210.8 KXX75193.1 - 2.4 7.8 3.7 22 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G FlaC_arch PF05377.6 KXX75193.1 - 3.2 7.7 29.3 0.37 10.7 0.7 6.8 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) AAA PF00004.24 KXX75194.1 - 2.7e-14 53.4 0.0 4.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX75194.1 - 1.4e-10 41.4 0.0 1.6e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX75194.1 - 1.2e-07 31.9 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75194.1 - 0.00021 22.1 0.0 0.001 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX75194.1 - 0.0012 18.5 0.5 0.0046 16.6 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KXX75194.1 - 0.0085 16.0 0.0 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KXX75194.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX75194.1 - 0.019 14.8 0.0 0.61 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KXX75194.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KXX75194.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KXX75194.1 - 0.042 13.2 0.0 2.7 7.3 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain DUF2075 PF09848.4 KXX75194.1 - 0.049 12.6 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 KXX75194.1 - 0.064 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KXX75194.1 - 0.07 12.8 0.0 0.51 9.9 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KXX75194.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PCI PF01399.22 KXX75195.1 - 2.8e-20 72.5 0.9 9.1e-20 70.9 0.1 2.3 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.1 KXX75195.1 - 8e-07 28.4 2.8 0.22 11.4 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75195.1 - 2e-06 27.1 3.0 4.4 7.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75195.1 - 0.00084 19.9 12.8 1.2 9.9 0.3 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat DDRGK PF09756.4 KXX75195.1 - 0.00094 18.6 0.2 0.00094 18.6 0.1 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_2 PF07719.12 KXX75195.1 - 0.0013 18.5 5.8 7.3 6.7 0.0 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX75195.1 - 0.01 15.4 5.9 7.1 6.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX75195.1 - 0.033 14.1 18.6 0.06 13.2 0.3 5.3 3 1 2 6 6 6 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KXX75195.1 - 0.036 13.8 0.3 0.077 12.7 0.2 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 KXX75195.1 - 0.1 13.2 12.1 17 6.3 0.1 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF87 PF01935.12 KXX75195.1 - 0.21 11.3 2.0 0.68 9.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 TPR_10 PF13374.1 KXX75195.1 - 0.41 10.6 4.3 9 6.3 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75195.1 - 0.51 10.9 0.1 0.51 10.9 0.1 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat AT_hook PF02178.14 KXX75196.1 - 0.0093 15.5 18.9 0.55 10.0 3.1 3.5 2 0 0 2 2 2 2 AT hook motif Kdo_hydroxy PF11004.3 KXX75197.1 - 0.13 11.2 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase OSCP PF00213.13 KXX75198.1 - 4.3e-45 153.6 0.5 5e-45 153.4 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Sds3 PF08598.6 KXX75199.1 - 1.4e-49 168.4 5.9 1.4e-49 168.4 4.1 1.7 1 1 1 2 2 2 1 Sds3-like AntA PF08346.7 KXX75199.1 - 0.044 13.9 0.7 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 AntA/AntB antirepressor LSM PF01423.17 KXX75200.1 - 1.1e-13 50.4 0.1 2.5e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 LSM domain Flexi_CP_N PF08358.5 KXX75201.1 - 0.019 14.7 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Carlavirus coat Mob1_phocein PF03637.12 KXX75202.1 - 6.2e-70 234.4 0.0 7.9e-70 234.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.11 KXX75203.1 - 1.5e-08 33.0 2.2 1.2e-05 23.4 0.0 3.2 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase CEP44 PF15007.1 KXX75203.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 PP2C PF00481.16 KXX75204.1 - 1.2e-42 146.1 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KXX75204.1 - 0.0018 17.7 0.3 0.0058 16.0 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KXX75204.1 - 0.0048 16.6 0.1 0.6 9.7 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) WD40 PF00400.27 KXX75205.1 - 1.6e-32 110.1 10.5 1.3e-08 34.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KXX75205.1 - 3.1e-32 110.4 14.3 5.4e-32 109.6 9.9 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KXX75205.1 - 6.6e-06 25.8 0.3 0.033 13.9 0.0 4.5 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KXX75205.1 - 0.0085 16.3 1.6 5.7 7.3 0.0 4.4 4 1 1 5 5 5 1 PQQ-like domain Cytochrom_D1 PF02239.11 KXX75205.1 - 0.0086 14.4 0.1 0.033 12.5 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain AAA PF00004.24 KXX75207.1 - 5.5e-07 29.8 0.0 1.3e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 KXX75207.1 - 0.0053 16.2 0.1 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_2 PF07724.9 KXX75207.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Histone PF00125.19 KXX75208.1 - 1.1e-27 95.9 0.2 1.6e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KXX75208.1 - 0.0006 19.9 0.0 0.00086 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KXX75208.1 - 0.063 13.3 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HLH PF00010.21 KXX75209.1 - 1.2e-12 47.3 0.0 2.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMBR PF09373.5 KXX75209.1 - 0.48 10.4 1.5 2.9 8.0 0.1 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat TPR_12 PF13424.1 KXX75210.1 - 1.3e-78 258.9 0.1 2e-17 62.9 0.0 5.2 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KXX75210.1 - 9.9e-71 231.8 0.0 1.1e-11 44.2 0.0 7.4 6 1 1 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75210.1 - 6.1e-18 63.2 2.5 0.045 13.6 0.0 6.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75210.1 - 6.5e-17 60.9 0.0 0.00069 19.2 0.1 4.4 2 2 2 4 4 4 4 TPR repeat TPR_7 PF13176.1 KXX75210.1 - 2.6e-13 48.6 5.1 0.1 12.4 0.0 7.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75210.1 - 8.9e-13 48.5 0.0 0.025 15.2 0.0 4.8 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75210.1 - 2.3e-12 46.0 2.3 0.17 12.3 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX75210.1 - 5.1e-11 41.6 0.7 0.44 10.2 0.0 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX75210.1 - 1.7e-10 40.2 0.6 0.99 9.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75210.1 - 3.5e-09 36.4 3.4 1 10.1 0.0 6.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX75210.1 - 6.9e-09 35.9 0.0 0.37 11.1 0.0 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX75210.1 - 7.1e-08 32.4 0.0 0.41 10.8 0.0 4.5 1 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF2664 PF10867.3 KXX75210.1 - 7.5e-07 29.6 0.0 20 5.9 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2664) TPR_6 PF13174.1 KXX75210.1 - 3.9e-06 26.9 8.8 7.5 7.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75210.1 - 5.9e-05 22.5 0.4 1.8 8.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 KXX75210.1 - 0.0034 17.2 4.9 14 5.9 0.0 6.1 6 1 1 7 7 7 0 PPR repeat PPR_3 PF13812.1 KXX75210.1 - 0.0066 16.6 1.7 3 8.3 0.1 4.4 5 0 0 5 5 4 1 Pentatricopeptide repeat domain TPR_3 PF07720.7 KXX75210.1 - 0.016 14.9 0.0 21 5.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1481 PF07356.7 KXX75210.1 - 0.052 12.9 1.3 2.1 7.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1481) DUF1697 PF08002.6 KXX75210.1 - 0.062 13.3 0.0 0.25 11.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1697) PPR_2 PF13041.1 KXX75210.1 - 0.27 11.2 2.0 29 4.7 0.0 4.6 5 2 2 7 7 7 0 PPR repeat family DUF1923 PF09083.5 KXX75210.1 - 1 8.8 7.6 53 3.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1923) TPR_10 PF13374.1 KXX75211.1 - 1.4e-42 142.3 0.0 6e-13 48.2 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX75211.1 - 3.2e-33 113.4 0.1 1.5e-15 56.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75211.1 - 5.7e-12 45.1 0.1 2e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 KXX75211.1 - 1.5e-09 36.9 0.9 0.021 14.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75211.1 - 4.6e-09 35.5 2.2 2 8.4 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat AAA_22 PF13401.1 KXX75211.1 - 5.5e-09 36.2 0.0 3.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 KXX75211.1 - 1.8e-08 33.6 2.0 1.3 8.7 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75211.1 - 2.3e-07 30.5 0.0 1.5 9.5 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 KXX75211.1 - 1.2e-06 27.6 0.0 2.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KXX75211.1 - 6.5e-06 26.6 0.0 0.32 11.7 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX75211.1 - 6.7e-06 26.3 0.1 0.29 11.4 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75211.1 - 2e-05 24.8 0.1 11 6.9 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX75211.1 - 0.00011 22.0 0.2 9.8 6.6 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KXX75211.1 - 0.00018 21.5 0.0 1.3 9.1 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KXX75211.1 - 0.00049 19.6 2.1 28 4.8 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat ArsA_ATPase PF02374.10 KXX75211.1 - 0.2 10.6 0.0 0.41 9.6 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_6 PF13174.1 KXX75211.1 - 0.23 12.0 1.8 2.5e+02 2.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ARD PF03079.9 KXX75212.1 - 8.6e-46 155.7 0.0 1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KXX75212.1 - 9.5e-09 34.6 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KXX75212.1 - 3.1e-05 23.6 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KXX75212.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin DER1 PF04511.10 KXX75213.1 - 1.4e-51 174.8 4.1 1.6e-51 174.6 2.8 1.0 1 0 0 1 1 1 1 Der1-like family MBOAT PF03062.14 KXX75215.1 - 1.9e-50 171.7 1.4 3.5e-50 170.9 1.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 KXX75215.1 - 0.00071 19.2 3.5 0.00071 19.2 2.4 2.4 2 1 0 2 2 2 1 PAP2 superfamily DUF2404 PF10296.4 KXX75216.1 - 9.5e-08 32.0 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Sec1 PF00995.18 KXX75217.1 - 8.3e-140 467.0 0.4 4.2e-138 461.4 0.2 2.0 1 1 0 1 1 1 1 Sec1 family Mod_r PF07200.8 KXX75217.1 - 0.042 13.7 0.5 0.091 12.6 0.3 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2088 PF09861.4 KXX75217.1 - 0.06 12.3 0.0 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2088) adh_short PF00106.20 KXX75219.1 - 1.9e-21 76.7 0.0 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX75219.1 - 3.5e-12 46.3 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX75219.1 - 4.3e-08 32.8 0.0 6.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KXX75219.1 - 4.1e-05 23.4 0.0 5.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KXX75219.1 - 9.1e-05 21.2 0.1 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KXX75219.1 - 0.0011 17.8 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KXX75219.1 - 0.0018 18.3 0.0 0.0034 17.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX75219.1 - 0.0023 16.8 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ribosomal_60s PF00428.14 KXX75219.1 - 0.0063 16.8 0.5 0.016 15.6 0.4 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein NmrA PF05368.8 KXX75219.1 - 0.024 13.9 0.1 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family UAA PF08449.6 KXX75220.1 - 2.3e-12 46.4 18.0 3.1e-12 46.0 12.5 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KXX75220.1 - 1.3e-09 37.9 6.2 1.3e-09 37.9 4.3 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KXX75220.1 - 0.0042 17.1 4.6 0.0042 17.1 3.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Abi PF02517.11 KXX75221.1 - 2.2e-12 46.9 7.5 2.2e-12 46.9 5.2 3.2 3 1 0 4 4 4 2 CAAX protease self-immunity PepSY_TM_2 PF13703.1 KXX75221.1 - 5.6 7.2 9.7 0.55 10.4 0.1 3.5 4 0 0 4 4 4 0 PepSY-associated TM helix GSH_synth_ATP PF03917.12 KXX75222.1 - 4.3e-36 124.2 0.0 4.9e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KXX75222.1 - 0.00095 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SUN PF03856.8 KXX75223.1 - 4.1e-83 278.5 12.1 5.3e-83 278.1 8.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RHSP PF07999.6 KXX75223.1 - 0.01 14.4 0.1 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein BNR PF02012.15 KXX75224.1 - 4e-14 50.0 30.2 0.092 12.6 0.2 11.4 11 0 0 11 11 11 6 BNR/Asp-box repeat DUF2561 PF10812.3 KXX75224.1 - 0.0074 15.9 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Proteasom_Rpn13 PF04683.8 KXX75224.1 - 0.022 14.8 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor DAGAT PF03982.8 KXX75225.1 - 5.9e-91 304.2 0.0 8.3e-91 303.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LAM_C PF12544.3 KXX75227.1 - 6.8e-05 22.9 0.1 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 KXX75227.1 - 0.0041 17.3 0.0 0.039 14.1 0.0 2.4 2 1 0 2 2 2 1 Radical SAM superfamily zf-H2C2_2 PF13465.1 KXX75228.1 - 4.9e-13 48.6 20.8 1.2e-07 31.6 1.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KXX75228.1 - 3.3e-09 36.5 26.7 0.0039 17.4 4.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX75228.1 - 0.00014 21.9 23.7 0.0078 16.4 4.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger TMCO5 PF14992.1 KXX75228.1 - 0.19 10.8 0.1 0.32 10.1 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family zf-CHCC PF10276.4 KXX75228.1 - 0.27 11.0 6.0 1.7 8.5 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_6 PF13912.1 KXX75228.1 - 0.51 10.3 0.1 0.51 10.3 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX75228.1 - 0.93 9.7 15.4 1.2 9.3 2.9 3.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KXX75228.1 - 2.1 7.8 4.3 0.49 9.8 0.4 1.9 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.6 KXX75228.1 - 2.5 7.7 6.0 12 5.6 1.0 2.5 1 1 1 2 2 2 0 GAGA factor DZR PF12773.2 KXX75228.1 - 3.1 7.6 6.8 38 4.2 4.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon COesterase PF00135.23 KXX75229.1 - 1.1e-92 311.5 0.0 1.3e-92 311.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX75229.1 - 0.00092 18.8 0.4 0.0018 17.9 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX75229.1 - 0.0011 18.7 0.2 0.0019 17.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX75229.1 - 0.11 11.7 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ATP_bind_4 PF01902.12 KXX75230.1 - 1.6e-21 76.7 0.0 1.1e-15 57.5 0.0 3.7 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 KXX75230.1 - 2.3e-08 33.8 0.4 1.3e-05 24.9 0.0 3.6 3 1 0 3 3 3 2 Endoribonuclease L-PSP DUF962 PF06127.6 KXX75231.1 - 3e-25 87.9 0.9 4.2e-25 87.4 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 KXX75232.1 - 4.4e-15 55.5 0.0 6.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KXX75232.1 - 4.8e-09 36.1 0.0 7.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain MFS_1 PF07690.11 KXX75233.1 - 1.4e-28 99.6 42.0 8.2e-21 74.0 11.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.4 KXX75233.1 - 0.012 15.1 0.2 0.012 15.1 0.1 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF2427) Pex24p PF06398.6 KXX75233.1 - 1.9 7.2 4.3 0.4 9.4 0.0 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF1996 PF09362.5 KXX75234.1 - 3.3e-76 256.0 0.2 4.1e-76 255.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HIPIP PF01355.12 KXX75234.1 - 0.095 12.8 2.3 11 6.1 0.0 2.7 3 0 0 3 3 3 0 High potential iron-sulfur protein Na_Ca_ex PF01699.19 KXX75235.1 - 2.1e-34 118.0 21.8 9.2e-21 73.9 5.6 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KXX75235.1 - 1.1e-14 54.5 13.0 1.1e-14 54.5 9.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) AAA PF00004.24 KXX75236.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX75236.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX75236.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KXX75236.1 - 3.2e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX75236.1 - 4.5e-06 26.8 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75236.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX75236.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX75236.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KXX75236.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KXX75236.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KXX75236.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KXX75236.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KXX75236.1 - 0.0022 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KXX75236.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KXX75236.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX75236.1 - 0.0065 16.7 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KXX75236.1 - 0.0069 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KXX75236.1 - 0.0075 15.4 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KXX75236.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 KXX75236.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KXX75236.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 KXX75236.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KXX75236.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX75236.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.4 KXX75236.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sigma54_activ_2 PF14532.1 KXX75236.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Histone PF00125.19 KXX75236.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 KXX75236.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KXX75236.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KXX75236.1 - 0.099 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RdRP PF05183.7 KXX75237.1 - 8.3e-155 516.7 0.0 1.2e-154 516.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KXX75237.1 - 1.1e-05 24.9 0.0 3.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75237.1 - 8.6e-05 22.4 0.0 0.00034 20.5 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.2 KXX75238.1 - 3.7e-27 95.7 0.3 1.2e-26 94.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX75238.1 - 5.8e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX75238.1 - 2.6e-05 23.9 0.0 0.00011 22.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 KXX75238.1 - 0.00031 21.6 0.3 0.15 13.0 0.1 2.8 2 0 0 2 2 2 2 EthD domain Ndr PF03096.9 KXX75238.1 - 0.0018 16.8 0.0 0.0042 15.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Esterase PF00756.15 KXX75238.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Histone PF00125.19 KXX75239.1 - 2.3e-22 78.8 0.1 3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX75239.1 - 4.6e-05 23.3 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.5 KXX75239.1 - 0.072 12.7 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 zf-C2H2_4 PF13894.1 KXX75240.1 - 0.073 13.4 0.1 7.3 7.1 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger F-box PF00646.28 KXX75241.1 - 1.9e-08 33.7 0.3 4.4e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX75241.1 - 3.8e-08 32.9 0.4 9e-08 31.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like DUF2688 PF10892.3 KXX75241.1 - 0.044 13.4 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Meth_synt_2 PF01717.13 KXX75242.1 - 1.3e-09 37.4 0.0 1.4e-07 30.7 0.0 2.7 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KXX75242.1 - 0.00043 19.6 0.0 0.0023 17.2 0.0 2.1 2 1 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Y_phosphatase PF00102.22 KXX75243.1 - 3.2e-55 187.0 0.0 5.9e-31 107.6 0.0 3.8 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 KXX75243.1 - 1.3e-10 41.5 0.0 3.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KXX75243.1 - 0.035 14.3 0.1 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KXX75243.1 - 0.073 12.6 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Inositol_P PF00459.20 KXX75244.1 - 5.1e-34 117.8 0.0 1.5e-33 116.3 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family R3H PF01424.17 KXX75245.1 - 2.8e-10 39.7 0.2 7.4e-10 38.3 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KXX75245.1 - 2.6e-08 33.7 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX75245.1 - 1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75245.1 - 9.5e-06 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 KXX75245.1 - 0.024 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 DUF3902 PF13042.1 KXX75246.1 - 0.011 15.0 0.5 0.026 13.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) RCC1 PF00415.13 KXX75247.1 - 5.9e-31 106.4 20.1 5.3e-08 32.9 0.3 7.2 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KXX75247.1 - 7e-22 76.4 32.2 2.3e-09 36.5 0.5 6.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.12 KXX75248.1 - 1e-15 57.3 0.0 1.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KXX75248.1 - 8.1e-07 29.0 0.0 2.6e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KXX75248.1 - 1.6e-06 28.4 0.1 4.6e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KXX75248.1 - 0.00094 18.3 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KXX75248.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 KXX75248.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KXX75248.1 - 0.032 13.8 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1752 PF08550.5 KXX75248.1 - 0.048 13.2 0.7 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) ApbA PF02558.11 KXX75248.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HA2 PF04408.18 KXX75249.1 - 1.7e-26 92.1 0.1 4.2e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KXX75249.1 - 2.1e-25 88.7 0.0 4.2e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KXX75249.1 - 4e-12 45.8 0.0 1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KXX75249.1 - 3.6e-08 33.3 0.2 7.1e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KXX75249.1 - 9.3e-07 28.4 0.1 2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX75249.1 - 2.7e-06 27.5 0.1 7.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KXX75249.1 - 8.5e-05 21.5 0.0 0.00022 20.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KXX75249.1 - 0.0019 18.0 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KXX75249.1 - 0.0042 16.8 0.7 0.014 15.1 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 KXX75249.1 - 0.027 13.7 0.2 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 KXX75249.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KXX75249.1 - 0.03 14.2 0.2 0.19 11.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX75249.1 - 0.037 14.3 0.4 0.3 11.3 0.1 2.5 1 1 1 2 2 2 0 ABC transporter AAA_25 PF13481.1 KXX75249.1 - 0.095 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KXX75249.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KXX75249.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KXX75249.1 - 0.16 11.0 0.1 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC DAP3 PF10236.4 KXX75249.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Myosin_head PF00063.16 KXX75249.1 - 0.19 9.7 0.0 0.29 9.1 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Herpes_ori_bp PF02399.10 KXX75249.1 - 0.19 9.6 0.0 0.28 9.0 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein DUF2075 PF09848.4 KXX75249.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Alk_phosphatase PF00245.15 KXX75250.1 - 1.4e-104 350.1 0.0 1.7e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KXX75250.1 - 6.5e-05 22.4 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily LRR_4 PF12799.2 KXX75251.1 - 0.0079 15.7 8.6 0.13 11.9 0.3 4.6 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) HHH_2 PF12826.2 KXX75251.1 - 0.14 12.0 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4259 PF14078.1 KXX75251.1 - 0.16 12.4 0.5 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Rad9 PF04139.8 KXX75252.1 - 2.6e-68 229.8 0.1 3.5e-68 229.4 0.1 1.1 1 0 0 1 1 1 1 Rad9 HEAT_2 PF13646.1 KXX75253.1 - 2.2e-15 56.7 17.5 0.00053 20.2 0.0 8.8 7 1 1 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 KXX75253.1 - 6.8e-09 36.0 0.2 0.0051 17.1 0.0 5.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KXX75253.1 - 8.4e-09 34.7 24.2 0.021 14.8 0.0 11.5 12 0 0 12 12 12 4 HEAT repeat CLASP_N PF12348.3 KXX75253.1 - 0.005 16.2 8.4 0.19 11.0 0.0 5.5 6 1 1 7 7 7 2 CLASP N terminal HEAT_EZ PF13513.1 KXX75253.1 - 0.053 14.0 23.2 0.79 10.2 0.5 9.4 7 1 2 9 9 9 0 HEAT-like repeat DUF1640 PF07798.6 KXX75254.1 - 2.7e-09 37.3 1.2 3.5e-09 36.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.2 KXX75255.1 - 2.4e-24 86.4 0.8 4.4e-24 85.6 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX75255.1 - 3.6e-16 59.2 0.0 8.4e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX75255.1 - 4.3e-10 39.5 0.0 1.2e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KXX75255.1 - 4.7e-09 35.9 0.0 9.2e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 KXX75255.1 - 0.00031 21.0 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 KXX75255.1 - 0.0027 17.3 0.2 0.0074 15.9 0.0 1.7 1 1 1 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 KXX75255.1 - 0.0081 15.7 0.2 0.042 13.4 0.2 1.9 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.22 KXX75255.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LCAT PF02450.10 KXX75255.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 KXX75255.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KXX75255.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF2305 PF10230.4 KXX75255.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PTPlike_phytase PF14566.1 KXX75255.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF900 PF05990.7 KXX75255.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Y_phosphatase3 PF13350.1 KXX75255.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Arf PF00025.16 KXX75258.1 - 2.6e-58 196.1 0.0 3.1e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KXX75258.1 - 3.2e-08 32.6 0.1 6.1e-08 31.7 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 KXX75258.1 - 2.7e-07 30.1 0.0 3.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KXX75258.1 - 9.4e-07 28.2 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KXX75258.1 - 1.5e-05 24.3 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KXX75258.1 - 0.00013 22.4 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KXX75258.1 - 0.0018 17.1 0.1 0.0038 16.0 0.1 1.5 1 1 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 KXX75258.1 - 0.002 17.5 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain VWA_CoxE PF05762.9 KXX75258.1 - 0.047 12.8 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein tRNA-synt_2d PF01409.15 KXX75259.1 - 2e-82 276.1 0.0 4.4e-82 274.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KXX75259.1 - 1.2e-07 30.8 0.3 0.00011 21.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KXX75259.1 - 3.4e-05 23.4 0.0 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_transf_22 PF03901.12 KXX75260.1 - 1.2e-60 205.7 17.3 1.4e-60 205.4 12.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KXX75260.1 - 0.11 12.4 15.4 0.039 13.8 7.7 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Skp1 PF01466.14 KXX75261.1 - 8.2e-40 134.7 2.1 8.2e-40 134.7 1.5 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KXX75261.1 - 2.3e-20 72.4 0.0 5.7e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KXX75261.1 - 0.034 14.1 1.7 0.043 13.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Transcrip_reg PF01709.15 KXX75262.1 - 2.2e-61 206.9 0.1 2.5e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF2346 PF09803.4 KXX75263.1 - 3.7e-05 23.5 2.8 6.7e-05 22.6 2.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) p450 PF00067.17 KXX75264.1 - 4.7e-64 216.6 0.0 4.4e-63 213.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Asn_synthase PF00733.16 KXX75265.1 - 3e-58 197.2 0.0 4.2e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KXX75265.1 - 1.4e-37 128.2 0.0 2.4e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KXX75265.1 - 3.4e-33 114.4 0.0 1.1e-32 112.7 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KXX75265.1 - 0.00017 20.4 0.0 0.017 13.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 KXX75265.1 - 0.0029 16.8 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein RRM_1 PF00076.17 KXX75265.1 - 0.15 11.6 0.1 0.89 9.2 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KXX75266.1 - 4.1e-62 210.2 0.0 5e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KXX75269.1 - 4.7e-18 65.0 0.9 8.9e-18 64.1 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75269.1 - 1.7e-06 27.8 0.0 4.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KXX75270.1 - 2.1e-35 122.0 52.9 4.2e-35 121.0 36.7 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX75270.1 - 2.8e-08 32.7 17.0 2.8e-08 32.7 11.8 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 KXX75270.1 - 0.0002 19.5 2.1 0.0002 19.5 1.4 2.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ketoacyl-synt PF00109.21 KXX75271.1 - 1.4e-74 250.7 0.0 3e-74 249.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX75271.1 - 5.7e-52 177.0 1.1 7e-52 176.7 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KXX75271.1 - 2.1e-51 174.8 1.4 3.9e-51 173.9 0.1 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 KXX75271.1 - 2.6e-49 167.3 2.3 2.8e-49 167.2 0.2 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KXX75271.1 - 1.5e-37 129.0 0.2 1.5e-37 129.0 0.1 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX75271.1 - 1.3e-33 115.3 0.1 4.5e-33 113.6 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX75271.1 - 3.6e-08 33.0 0.2 9.5e-08 31.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX75271.1 - 1.2e-06 28.6 0.1 4.3e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KXX75271.1 - 3.5e-05 22.9 0.0 8.4e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.16 KXX75271.1 - 0.19 11.4 0.0 0.53 10.0 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Sed5p PF11416.3 KXX75272.1 - 0.016 14.5 0.3 0.036 13.4 0.2 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p ADH_zinc_N_2 PF13602.1 KXX75273.1 - 4.8e-11 43.6 0.1 1.1e-10 42.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX75273.1 - 2.6e-10 39.9 0.0 5.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KXX75273.1 - 9.8e-06 25.6 0.2 2.1e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 KXX75273.1 - 5.3e-05 22.9 0.0 0.00088 19.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 KXX75273.1 - 0.0021 17.3 0.1 0.0032 16.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KXX75273.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KXX75273.1 - 0.0069 16.1 0.5 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_IV_N PF12462.3 KXX75273.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal RmlD_sub_bind PF04321.12 KXX75273.1 - 0.011 14.6 0.2 0.073 11.9 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 KXX75273.1 - 0.024 14.0 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_S16 PF00886.14 KXX75273.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S16 DapB_N PF01113.15 KXX75273.1 - 0.11 12.4 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FSH1 PF03959.8 KXX75274.1 - 8.1e-32 110.3 0.0 2.5e-31 108.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX75274.1 - 5.1e-09 36.3 0.0 6.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX75274.1 - 9.7e-05 21.9 0.3 0.057 12.8 0.2 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KXX75274.1 - 0.11 12.1 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.6 KXX75276.1 - 1e-36 126.1 0.1 1.8e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 KXX75276.1 - 0.0058 15.9 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4003) ADH_zinc_N PF00107.21 KXX75277.1 - 1.2e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX75277.1 - 2.2e-08 33.8 0.1 1.8e-06 27.6 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KXX75277.1 - 0.00082 20.2 0.0 0.0023 18.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pet127 PF08634.5 KXX75278.1 - 1.1e-119 398.6 0.9 1.7e-119 398.0 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Rhomboid PF01694.17 KXX75279.1 - 2.6e-35 121.5 8.9 2.6e-35 121.5 6.2 2.4 3 0 0 3 3 3 1 Rhomboid family TPPK_C PF12555.3 KXX75279.1 - 4 7.2 8.6 19 5.0 2.4 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Abhydrolase_1 PF00561.15 KXX75280.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX75280.1 - 2e-09 37.6 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX75280.1 - 0.00017 21.3 0.0 0.00053 19.7 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 KXX75280.1 - 0.0031 17.2 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Cutinase VirJ PF06057.6 KXX75280.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF4554 PF15091.1 KXX75281.1 - 0.96 8.1 6.0 1.3 7.7 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Metal_resist PF13801.1 KXX75282.1 - 0.56 10.2 8.4 0.2 11.6 2.1 2.3 1 1 1 2 2 2 0 Heavy-metal resistance Cohesin_load PF10345.4 KXX75283.1 - 9.6e-168 559.1 5.9 1.2e-167 558.8 4.1 1.1 1 0 0 1 1 1 1 Cohesin loading factor CN_hydrolase PF00795.17 KXX75284.1 - 2.1e-15 56.5 0.0 3.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.17 KXX75285.1 - 1.4e-10 40.8 0.0 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DER1 PF04511.10 KXX75288.1 - 1.5e-27 96.4 1.5 1.7e-27 96.1 1.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF2269 PF10027.4 KXX75288.1 - 0.095 12.4 1.7 0.11 12.3 0.3 1.7 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ArgJ PF01960.13 KXX75289.1 - 3.5e-148 493.1 0.1 4e-148 492.9 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.6 KXX75290.1 - 6.6e-20 70.8 0.0 1.3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KXX75290.1 - 3.4e-12 46.7 0.0 6.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KXX75290.1 - 1.3e-11 44.3 0.0 1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KXX75290.1 - 9e-08 32.0 0.0 2.8e-07 30.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX75290.1 - 3.5e-06 27.1 0.1 0.00011 22.2 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KXX75290.1 - 3.6e-06 26.2 0.0 1e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KXX75290.1 - 1.8e-05 24.8 0.1 0.023 14.8 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_3 PF07726.6 KXX75290.1 - 3.5e-05 23.4 0.0 7.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX75290.1 - 7.6e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KXX75290.1 - 0.00018 20.3 0.0 0.095 11.3 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KXX75290.1 - 0.00039 19.9 0.0 0.04 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 KXX75290.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 KXX75290.1 - 0.0018 18.0 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KXX75290.1 - 0.0032 16.6 0.0 0.033 13.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KXX75290.1 - 0.0033 16.8 0.0 0.054 12.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 KXX75290.1 - 0.006 16.3 0.5 0.03 14.0 0.1 2.2 2 1 0 3 3 2 1 NTPase DNA_pol3_gamma3 PF12169.3 KXX75290.1 - 0.0065 16.2 0.3 0.4 10.4 0.0 2.9 3 1 0 3 3 2 1 DNA polymerase III subunits gamma and tau domain III KTI12 PF08433.5 KXX75290.1 - 0.0065 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DEAD PF00270.24 KXX75290.1 - 0.0085 15.6 0.1 0.37 10.2 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase ArgK PF03308.11 KXX75290.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 KXX75290.1 - 0.012 15.5 0.0 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KXX75290.1 - 0.016 14.7 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KXX75290.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX75290.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KXX75290.1 - 0.025 14.3 0.1 0.11 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KXX75290.1 - 0.13 11.2 0.1 1.4 7.8 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF1232 PF06803.7 KXX75291.1 - 0.11 11.9 0.3 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) IGPD PF00475.13 KXX75292.1 - 1.4e-60 203.3 0.3 2e-60 202.8 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase FGase PF05013.7 KXX75292.1 - 0.05 13.4 0.1 0.092 12.6 0.1 1.5 1 1 0 1 1 1 0 N-formylglutamate amidohydrolase BCS1_N PF08740.6 KXX75293.1 - 2.9e-27 95.5 0.0 4.6e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KXX75293.1 - 6.2e-17 62.0 0.0 1.1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX75293.1 - 0.00037 21.3 0.0 0.0013 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX75293.1 - 0.00078 18.8 0.0 0.002 17.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX75293.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX75293.1 - 0.017 15.1 0.1 0.039 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KXX75293.1 - 0.027 13.3 0.0 0.098 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX75293.1 - 0.035 13.6 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KXX75293.1 - 0.05 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Uds1 PF15456.1 KXX75293.1 - 0.071 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Up-regulated During Septation Zeta_toxin PF06414.7 KXX75293.1 - 0.098 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KXX75293.1 - 0.11 11.2 0.0 0.81 8.3 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 KXX75293.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KXX75293.1 - 0.15 11.5 0.0 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain HET PF06985.6 KXX75294.1 - 2.6e-25 89.1 0.0 4.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SpoVAD PF07451.6 KXX75294.1 - 0.036 12.5 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Peptidase_S8 PF00082.17 KXX75295.1 - 2.1e-31 109.1 3.2 3.9e-31 108.2 2.2 1.4 1 0 0 1 1 1 1 Subtilase family FHA PF00498.21 KXX75296.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain YcaO PF02624.11 KXX75296.1 - 0.022 14.2 0.1 0.069 12.6 0.0 1.8 2 0 0 2 2 2 0 YcaO-like family RRM_1 PF00076.17 KXX75297.1 - 1.3e-59 197.7 0.1 2e-19 68.9 0.0 5.9 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75297.1 - 2e-46 155.7 0.2 6.7e-14 51.6 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75297.1 - 5.2e-21 74.2 0.7 5.9e-08 32.4 0.0 4.7 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_BLLF1 PF05109.8 KXX75298.1 - 0.88 7.4 9.8 1.3 6.9 6.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Cast PF10174.4 KXX75299.1 - 0.00064 17.9 31.0 0.0019 16.3 14.8 2.0 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.3 KXX75299.1 - 0.0091 15.7 23.4 0.076 12.8 4.5 4.3 2 2 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF3166 PF11365.3 KXX75299.1 - 0.03 14.7 2.6 0.03 14.7 1.8 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3166) p450 PF00067.17 KXX75299.1 - 0.19 10.1 8.5 0.2 10.1 0.9 2.2 1 1 0 2 2 2 0 Cytochrome P450 Ribonuc_red_lgN PF00317.16 KXX75299.1 - 0.2 11.4 1.3 5.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain Reo_sigmaC PF04582.7 KXX75299.1 - 0.46 9.6 6.9 1.3 8.1 2.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SPARC_Ca_bdg PF10591.4 KXX75299.1 - 2.7 8.0 6.6 12 6.0 0.1 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SlyX PF04102.7 KXX75299.1 - 8.8 6.7 26.5 0.3 11.4 0.2 5.3 1 1 3 5 5 5 0 SlyX TPR_12 PF13424.1 KXX75301.1 - 1.5e-35 121.0 1.6 2.1e-17 62.8 0.1 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KXX75301.1 - 2.4e-31 106.7 3.6 3.9e-14 52.0 0.0 3.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX75301.1 - 2.9e-07 29.7 0.2 0.00065 19.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX75301.1 - 3.5e-06 26.7 0.1 0.027 14.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75301.1 - 9.8e-06 25.1 0.7 0.003 17.1 0.2 2.4 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KXX75301.1 - 1.9e-05 24.2 0.3 0.053 13.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75301.1 - 3e-05 24.0 0.9 0.39 11.2 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX75301.1 - 4.6e-05 22.8 0.1 0.056 13.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2664 PF10867.3 KXX75301.1 - 0.0012 19.4 0.0 7.6 7.2 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2664) TPR_5 PF12688.2 KXX75301.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_19 PF14559.1 KXX75301.1 - 0.002 18.4 0.0 0.17 12.2 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75301.1 - 0.0042 17.7 0.1 0.18 12.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75301.1 - 0.019 14.7 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75301.1 - 0.028 15.0 0.3 1.3 9.8 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 KXX75301.1 - 0.034 14.2 0.1 6.5 6.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1858 PF08984.6 KXX75301.1 - 0.057 13.0 0.0 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) TPR_6 PF13174.1 KXX75301.1 - 0.065 13.7 0.5 2.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Nic96 PF04097.9 KXX75301.1 - 0.068 11.2 0.0 3.3 5.7 0.0 2.0 1 1 1 2 2 2 0 Nup93/Nic96 Osmo_CC PF08946.5 KXX75301.1 - 0.16 12.0 0.1 25 5.0 0.0 2.9 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DnaJ PF00226.26 KXX75302.1 - 8.5e-10 38.2 0.0 0.0014 18.3 0.0 4.0 4 0 0 4 4 4 2 DnaJ domain Pheromone PF08015.6 KXX75302.1 - 2.1 9.2 6.1 1.9 9.4 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone FAD_binding_8 PF08022.7 KXX75303.1 - 1.3e-09 37.8 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KXX75303.1 - 0.0005 20.1 0.1 0.0005 20.1 0.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KXX75303.1 - 0.00064 19.6 0.0 0.0098 15.8 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KXX75303.1 - 0.057 13.5 0.3 0.057 13.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ank_4 PF13637.1 KXX75304.1 - 3.6e-51 170.6 14.4 6.4e-10 39.2 0.1 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX75304.1 - 1.8e-46 156.4 2.7 7.9e-18 64.5 0.4 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75304.1 - 7.7e-42 139.0 5.1 1.5e-05 24.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KXX75304.1 - 4.5e-35 118.8 9.4 4.8e-10 39.3 0.2 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75304.1 - 6e-32 106.5 2.4 0.0013 18.7 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat DUF3447 PF11929.3 KXX75304.1 - 0.086 12.6 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) SchA_CurD PF04486.7 KXX75304.1 - 0.098 12.5 0.5 13 5.6 0.0 3.1 1 1 4 5 5 5 0 SchA/CurD like domain HET PF06985.6 KXX75307.1 - 4.5e-23 81.9 0.0 6.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAPS_reduct PF01507.14 KXX75309.1 - 3.5e-20 72.5 0.0 1.8e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family IU_nuc_hydro PF01156.14 KXX75310.1 - 2.1e-22 79.7 0.0 2.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SH3_1 PF00018.23 KXX75312.1 - 3.4e-12 45.5 0.2 1.4e-11 43.6 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KXX75312.1 - 1.7e-10 40.3 0.1 1.4e-09 37.3 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KXX75312.1 - 1.5e-08 33.9 0.0 6.5e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DUF2151 PF10221.4 KXX75312.1 - 2.9 5.9 4.1 4.6 5.2 2.8 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator eIF-3c_N PF05470.7 KXX75312.1 - 5.7 4.8 7.3 11 3.9 5.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Aldedh PF00171.17 KXX75313.1 - 4.2e-133 444.0 0.0 4.8e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX75313.1 - 0.024 13.3 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Methyltransf_PK PF05891.7 KXX75314.1 - 1.9e-29 102.5 0.0 2.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 KXX75314.1 - 0.089 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Carb_bind PF10645.4 KXX75315.1 - 4.4e-28 96.8 4.3 1.1e-27 95.6 3.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding IGFL PF14653.1 KXX75315.1 - 0.26 11.3 2.3 2.2 8.3 1.5 2.3 1 1 1 2 2 2 0 Insulin growth factor-like family CorA PF01544.13 KXX75317.1 - 3e-27 95.4 4.5 2e-23 82.8 1.7 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Cad PF03596.8 KXX75317.1 - 0.036 13.7 0.5 0.058 13.0 0.3 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter WD40 PF00400.27 KXX75318.1 - 4e-145 467.1 70.8 1.5e-12 46.9 1.5 13.8 13 0 0 13 13 13 13 WD domain, G-beta repeat Nup160 PF11715.3 KXX75318.1 - 1.7e-21 76.0 34.1 0.031 12.4 0.1 12.4 3 3 9 12 12 12 12 Nucleoporin Nup120/160 NACHT PF05729.7 KXX75318.1 - 9.8e-19 67.6 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KXX75318.1 - 1.1e-07 32.0 0.0 8.3e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75318.1 - 9.6e-07 28.3 0.0 2.7e-05 23.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Cytochrom_D1 PF02239.11 KXX75318.1 - 3.3e-05 22.3 8.2 0.18 10.0 0.3 4.5 3 1 0 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KXX75318.1 - 3.4e-05 22.7 21.1 0.058 12.1 1.6 6.5 1 1 6 7 7 7 3 Nup133 N terminal like Ank_3 PF13606.1 KXX75318.1 - 0.0015 18.5 0.0 0.15 12.4 0.0 3.8 4 0 0 4 4 3 1 Ankyrin repeat AAA_19 PF13245.1 KXX75318.1 - 0.0019 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Ank_5 PF13857.1 KXX75318.1 - 0.0093 16.1 0.1 0.044 14.0 0.0 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KXX75318.1 - 0.012 15.7 0.0 0.19 11.8 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.1 KXX75318.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MOZ_SAS PF01853.13 KXX75320.1 - 3.7e-79 264.3 0.1 5.3e-79 263.8 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KXX75320.1 - 0.00015 21.3 8.4 0.00015 21.3 5.8 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KXX75320.1 - 0.011 14.9 0.6 0.011 14.9 0.4 1.9 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.17 KXX75320.1 - 0.097 12.4 1.8 0.23 11.1 1.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 KXX75320.1 - 0.15 11.9 3.8 0.65 9.9 2.6 2.2 1 0 0 1 1 1 0 Rubredoxin zf-MIZ PF02891.15 KXX75320.1 - 7 6.2 7.0 0.56 9.7 1.4 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger F-box-like PF12937.2 KXX75321.1 - 3.9e-07 29.6 0.1 3.9e-07 29.6 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KXX75321.1 - 0.0001 21.8 0.2 0.00033 20.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.19 KXX75323.1 - 1e-14 53.9 23.3 1.5e-13 50.1 3.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX75323.1 - 1.2e-08 34.1 29.2 1.2e-08 34.1 20.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TPT PF03151.11 KXX75323.1 - 0.0017 18.0 7.1 0.0029 17.2 0.4 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family p450 PF00067.17 KXX75324.1 - 6e-40 137.1 0.0 7.5e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEX11 PF05648.9 KXX75325.1 - 1.9e-75 252.9 0.9 2.1e-75 252.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Chal_sti_synt_N PF00195.14 KXX75326.1 - 6.5e-22 77.8 0.0 9.3e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 KXX75326.1 - 4.7e-10 39.5 0.0 4.2e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 KXX75326.1 - 5.3e-08 32.2 0.0 7.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 KXX75326.1 - 0.00028 20.4 0.0 0.00094 18.7 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP2C_C PF07830.8 KXX75326.1 - 0.018 15.1 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF2360 PF10152.4 KXX75326.1 - 0.11 12.8 0.3 1.6 9.0 0.0 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) NMO PF03060.10 KXX75327.1 - 3.2e-64 217.1 0.1 4.2e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KXX75327.1 - 1.5e-11 43.8 0.0 4.4e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX75327.1 - 0.03 13.1 0.1 0.054 12.3 0.1 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NanE PF04131.9 KXX75327.1 - 0.055 12.4 1.2 0.061 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF1902 PF08972.6 KXX75327.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Thiolase_N PF00108.18 KXX75328.1 - 2.6e-77 259.3 3.8 3.6e-77 258.9 2.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX75328.1 - 3.7e-44 149.0 0.1 7.3e-44 148.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KXX75328.1 - 0.0087 15.5 1.3 0.025 14.0 0.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KXX75328.1 - 0.09 12.8 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FBPase PF00316.15 KXX75329.1 - 3.6e-125 417.1 0.0 4.1e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase NdhM PF10664.4 KXX75329.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Hemerythrin PF01814.18 KXX75330.1 - 7.3e-16 58.5 7.2 1e-15 58.0 5.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain ALIX_LYPXL_bnd PF13949.1 KXX75330.1 - 0.024 13.6 1.6 0.03 13.2 0.4 1.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV HD_3 PF13023.1 KXX75330.1 - 0.066 12.9 3.1 0.041 13.6 1.0 1.5 2 0 0 2 2 2 0 HD domain RNase_E_G PF10150.4 KXX75330.1 - 0.22 10.7 1.4 0.32 10.1 1.0 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family zf-C2H2_2 PF12756.2 KXX75330.1 - 3.2 7.9 5.7 3.2 7.9 1.8 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ATP_bind_3 PF01171.15 KXX75331.1 - 3.5e-17 62.4 0.0 5.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KXX75331.1 - 0.00037 19.8 0.8 0.00037 19.8 0.6 3.1 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 KXX75331.1 - 0.0027 18.0 0.0 0.0068 16.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KXX75331.1 - 0.0061 15.1 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase zf-UBR PF02207.15 KXX75331.1 - 0.094 12.4 5.4 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) OCD_Mu_crystall PF02423.10 KXX75333.1 - 6.4e-12 44.8 6.5 9.7e-10 37.7 4.5 2.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DUF3530 PF12048.3 KXX75333.1 - 0.053 12.5 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) NAD_binding_7 PF13241.1 KXX75333.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 KXX75333.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) TRAUB PF08164.7 KXX75334.1 - 8.4e-32 109.1 1.0 3.3e-31 107.2 0.1 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KXX75334.1 - 2.6e-31 108.5 0.9 2.6e-31 108.5 0.6 3.3 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF2457 PF10446.4 KXX75334.1 - 0.0048 15.6 25.2 0.0048 15.6 17.5 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF2457) Katanin_con80 PF13925.1 KXX75334.1 - 0.076 12.7 0.2 0.82 9.3 0.1 2.3 2 0 0 2 2 2 0 con80 domain of Katanin Ribosomal_L7Ae PF01248.21 KXX75335.1 - 4.2e-21 74.2 0.9 7.9e-21 73.3 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.7 KXX75335.1 - 0.063 11.9 0.1 0.077 11.6 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pam17 PF08566.5 KXX75335.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 Pro_CA PF00484.14 KXX75336.1 - 1.9e-45 154.6 0.1 2.3e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ParA PF10609.4 KXX75337.1 - 9.9e-32 108.6 0.0 1.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KXX75337.1 - 3.7e-12 46.0 0.0 5.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KXX75337.1 - 7e-07 29.2 0.1 1.7e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KXX75337.1 - 0.00049 19.2 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 KXX75337.1 - 0.00092 18.4 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 KXX75337.1 - 0.0031 16.5 0.1 0.0082 15.2 0.1 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 KXX75337.1 - 0.0049 16.4 0.2 0.078 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KXX75337.1 - 0.072 11.8 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 KXX75337.1 - 0.085 12.2 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 KXX75337.1 - 0.15 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 YhjQ protein DUF4537 PF15057.1 KXX75338.1 - 0.012 15.4 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) UQ_con PF00179.21 KXX75339.1 - 9.7e-35 119.0 0.0 1.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 KXX75340.1 - 1.9e-55 188.3 0.0 2.3e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1778 PF08681.6 KXX75340.1 - 0.014 15.2 0.1 0.039 13.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2526 PF10735.4 KXX75340.1 - 0.57 10.2 3.1 1.1 9.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Annexin PF00191.15 KXX75341.1 - 4.5e-22 77.7 0.5 9.1e-06 25.4 0.0 4.7 4 1 0 4 4 4 4 Annexin Zn_clus PF00172.13 KXX75342.1 - 2.7e-08 33.5 11.8 5e-08 32.7 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Corona_nucleoca PF00937.13 KXX75342.1 - 0.45 9.4 6.7 0.86 8.4 4.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SSP160 PF06933.6 KXX75342.1 - 0.97 7.3 8.3 1.4 6.8 5.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 APG12 PF04110.8 KXX75343.1 - 1e-25 89.7 0.0 1.3e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KXX75343.1 - 6.5e-05 22.8 0.0 8.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 KXX75344.1 - 1.4e-105 352.1 0.2 1.7e-105 351.8 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KXX75344.1 - 8.5e-11 41.5 1.0 1.1e-10 41.1 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase GPI2 PF06432.6 KXX75345.1 - 2e-92 309.5 0.1 3e-44 151.4 0.0 3.0 3 0 0 3 3 3 3 Phosphatidylinositol N-acetylglucosaminyltransferase CNH PF00780.17 KXX75346.1 - 3.5e-68 229.9 0.0 5.6e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KXX75346.1 - 3.5e-31 108.4 0.0 5.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KXX75346.1 - 1.5e-11 44.3 0.0 2.9e-10 40.2 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KXX75346.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 PH domain Pet191_N PF10203.4 KXX75347.1 - 7.7e-29 99.5 4.1 1e-28 99.1 2.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Clusterin PF01093.12 KXX75347.1 - 1.1 8.0 3.7 1.4 7.6 2.6 1.1 1 0 0 1 1 1 0 Clusterin Abhydro_lipase PF04083.11 KXX75348.1 - 6.7e-22 76.6 0.1 1.4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KXX75348.1 - 4.8e-19 68.8 0.1 8.3e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KXX75348.1 - 0.00066 19.1 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Transaldolase PF00923.14 KXX75349.1 - 9.9e-92 307.1 0.9 1.1e-91 306.9 0.6 1.0 1 0 0 1 1 1 1 Transaldolase Metallophos PF00149.23 KXX75350.1 - 3.4e-11 42.9 0.2 4.7e-09 35.9 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KXX75350.1 - 1.8e-09 37.5 0.1 3.4e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.1 KXX75350.1 - 0.69 10.2 21.1 0.78 10.0 0.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_UL6 PF01763.11 KXX75351.1 - 0.084 11.0 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Sec20 PF03908.8 KXX75352.1 - 0.022 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Sec20 Sod_Cu PF00080.15 KXX75353.1 - 4.8e-45 153.1 5.1 5.6e-45 152.9 3.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 KXX75354.1 - 1.6e-71 237.4 1.8 2.4e-22 79.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KXX75354.1 - 6.6e-25 87.3 0.0 1.6e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 KXX75354.1 - 2.4e-07 30.1 0.0 5.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) AFG1_ATPase PF03969.11 KXX75355.1 - 1.5e-53 181.9 0.0 2.5e-24 85.7 0.0 5.0 3 2 2 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.9 KXX75355.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX75355.1 - 0.007 16.3 0.1 0.041 13.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 KXX75355.1 - 0.008 15.1 0.1 0.086 11.8 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.1 KXX75355.1 - 0.011 15.8 0.0 0.047 13.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX75355.1 - 0.062 13.6 0.2 1.1 9.5 0.0 2.7 2 1 1 3 3 3 0 ABC transporter DUF4149 PF13664.1 KXX75355.1 - 0.079 13.0 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) AAA_14 PF13173.1 KXX75355.1 - 0.097 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX75355.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KXX75355.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KXX75355.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KXX75355.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Glyco_transf_90 PF05686.7 KXX75356.1 - 1.7e-19 69.7 0.0 1e-17 63.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Aldedh PF00171.17 KXX75357.1 - 8.7e-83 278.1 0.0 1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YxiJ PF14176.1 KXX75357.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 YxiJ-like protein MRP-S28 PF10213.4 KXX75358.1 - 3e-48 163.0 0.3 1.1e-47 161.2 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein ECR1_N PF14382.1 KXX75360.1 - 1.5e-11 43.3 0.0 3.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KXX75360.1 - 0.0026 17.6 0.1 0.016 15.1 0.0 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 KXX75360.1 - 0.0059 16.6 2.2 1.3 9.2 0.0 3.5 4 0 0 4 4 4 2 S1 RNA binding domain EGF_CA PF07645.10 KXX75361.1 - 0.02 14.8 3.4 0.05 13.5 2.3 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain HET PF06985.6 KXX75362.1 - 9.5e-20 71.1 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl_transf_1 PF00698.16 KXX75363.1 - 1.8e-19 70.2 0.1 1.4e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.9 KXX75364.1 - 8.4e-106 354.8 17.1 1e-105 354.5 11.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KXX75364.1 - 3.8e-91 305.9 0.0 5.1e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 KXX75365.1 - 1.3e-45 151.6 31.6 7.2e-08 32.0 0.1 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat PD40 PF07676.7 KXX75365.1 - 0.033 13.8 0.0 2.6 7.7 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_tran_28_C PF04101.11 KXX75366.1 - 2.3e-17 63.1 0.7 3.6e-16 59.2 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ECH PF00378.15 KXX75366.1 - 0.018 14.1 0.7 0.058 12.5 0.5 1.6 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family DUF3043 PF11241.3 KXX75366.1 - 0.14 11.6 3.4 0.23 11.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HECT PF00632.20 KXX75367.1 - 5.6e-92 308.2 0.0 8.3e-92 307.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KXX75367.1 - 5e-33 112.5 20.9 4.9e-11 42.2 4.0 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KXX75367.1 - 3.1e-16 58.9 0.1 9.5e-16 57.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 KXX75368.1 - 9e-17 60.4 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75368.1 - 1e-16 60.6 0.3 2.1e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75368.1 - 2.2e-07 30.5 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 KXX75368.1 - 0.0025 15.7 0.9 0.003 15.5 0.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 KXX75368.1 - 0.11 11.5 2.6 0.13 11.3 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KXX75368.1 - 0.18 11.7 4.1 0.25 11.2 2.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KXX75368.1 - 0.42 10.1 4.2 0.65 9.5 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX75368.1 - 0.57 9.7 3.0 0.68 9.4 2.0 1.1 1 0 0 1 1 1 0 IncA protein GRP PF07172.6 KXX75368.1 - 6.9 7.2 18.7 0.16 12.4 8.2 1.8 2 1 0 2 2 2 0 Glycine rich protein family Sedlin_N PF04628.8 KXX75369.1 - 5.3e-20 71.6 0.0 6.3e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BA14K PF07886.6 KXX75369.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 BA14K-like protein Ribul_P_3_epim PF00834.14 KXX75370.1 - 3.3e-64 215.6 0.0 4.3e-31 107.6 0.0 2.1 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 KXX75370.1 - 0.061 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 KXX75370.1 - 0.071 12.6 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Aminotran_5 PF00266.14 KXX75371.1 - 8.5e-50 169.5 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KXX75371.1 - 9e-06 24.2 0.1 1.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Rad17 PF03215.10 KXX75372.1 - 1.4e-54 185.6 0.0 3.8e-54 184.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KXX75372.1 - 0.00033 20.3 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KXX75372.1 - 0.00096 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KXX75372.1 - 0.0027 17.3 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX75372.1 - 0.0042 17.2 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX75372.1 - 0.0072 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KXX75372.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX75372.1 - 0.043 14.6 0.0 0.097 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KXX75372.1 - 0.065 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 KXX75372.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 KXX75372.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KXX75372.1 - 0.21 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KXX75372.1 - 0.24 11.6 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PPV_E1_C PF00519.12 KXX75372.1 - 0.35 9.4 0.0 0.53 8.8 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase ORC6 PF05460.8 KXX75372.1 - 9.9 5.1 8.9 21 4.0 6.2 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4243 PF14027.1 KXX75373.1 - 2.7e-89 299.8 0.9 3.2e-89 299.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) APH PF01636.18 KXX75374.1 - 8.6e-46 156.5 0.9 1.3e-45 156.0 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KXX75374.1 - 8.6e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KXX75374.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KXX75374.1 - 0.0019 17.2 0.0 0.009 15.0 0.0 2.0 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 KXX75374.1 - 0.014 14.7 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Ank PF00023.25 KXX75375.1 - 6e-14 51.0 0.4 1.2e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KXX75375.1 - 1.8e-12 47.4 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX75375.1 - 4e-11 43.1 0.1 4.3e-10 39.8 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75375.1 - 4.1e-10 38.9 0.0 1.8e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KXX75375.1 - 8e-09 35.4 0.1 5.9e-06 26.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GSK-3_bind PF05350.7 KXX75375.1 - 0.3 10.4 3.9 0.44 9.9 2.7 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Metallophos PF00149.23 KXX75376.1 - 6.5e-09 35.4 0.5 1.2e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.1 KXX75376.1 - 0.0099 16.1 13.0 0.018 15.3 3.6 2.7 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.7 KXX75376.1 - 0.45 8.8 19.6 0.44 8.8 7.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NST1 PF13945.1 KXX75376.1 - 3.8 7.5 7.9 8.2 6.4 0.2 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Ofd1_CTDD PF10637.4 KXX75377.1 - 1.7e-103 345.4 0.0 2.1e-95 318.9 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KXX75377.1 - 1.4e-14 54.4 0.0 5.7e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KXX75377.1 - 0.054 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.15 KXX75379.1 - 3.6e-54 183.5 0.0 7e-54 182.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sybindin PF04099.7 KXX75380.1 - 8.3e-54 181.1 0.0 9.5e-54 180.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KXX75380.1 - 3.1e-09 36.8 0.0 6e-09 35.8 0.0 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 KXX75381.1 - 2.7e-13 50.3 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX75381.1 - 1.4e-06 28.1 0.2 2.1e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KXX75381.1 - 2.3e-06 27.3 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KXX75381.1 - 0.00031 20.0 1.3 0.00098 18.4 0.9 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 KXX75382.1 - 2.5e-22 78.0 2.9 3.8e-22 77.4 2.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.17 KXX75383.1 - 5.1e-23 80.6 0.3 1.1e-22 79.6 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 KXX75383.1 - 0.00073 19.4 0.1 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF4603 PF15376.1 KXX75383.1 - 0.037 11.2 1.2 0.04 11.1 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) She9_MDM33 PF05546.6 KXX75383.1 - 0.069 12.6 1.0 0.098 12.1 0.7 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family FYRC PF05965.9 KXX75383.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus Methyltransf_11 PF08241.7 KXX75384.1 - 9.6e-12 45.2 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX75384.1 - 0.0079 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KXX75384.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX75384.1 - 0.025 15.0 0.0 0.08 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75384.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KXX75384.1 - 0.23 11.0 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase zf-C2H2_4 PF13894.1 KXX75385.1 - 0.013 15.7 31.8 0.1 12.9 0.0 7.3 7 0 0 7 7 7 0 C2H2-type zinc finger Zn_clus PF00172.13 KXX75385.1 - 0.13 12.1 4.1 0.49 10.3 2.8 2.0 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KXX75387.1 - 4.8e-22 78.6 0.0 7.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PgaD PF13994.1 KXX75387.1 - 0.038 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein MARVEL PF01284.18 KXX75393.1 - 0.97 9.2 11.8 0.87 9.4 1.0 3.0 2 1 0 3 3 3 0 Membrane-associating domain DAO PF01266.19 KXX75395.1 - 1e-40 139.7 4.5 1.3e-40 139.3 3.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX75395.1 - 0.00057 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GARS_N PF02844.10 KXX75395.1 - 0.0031 17.9 0.0 0.085 13.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain NAD_binding_9 PF13454.1 KXX75395.1 - 0.0077 16.0 0.1 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX75395.1 - 0.052 13.6 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S15 PF02129.13 KXX75396.1 - 3.8e-42 144.5 0.3 5.4e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KXX75396.1 - 5e-33 114.8 0.0 7.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KXX75396.1 - 3.7e-06 26.9 0.5 6.8e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX75396.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 KXX75397.1 - 2.4e-53 181.2 0.0 4.8e-53 180.2 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX75397.1 - 1.1e-31 110.0 0.1 6e-31 107.6 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX75397.1 - 3.4e-09 36.0 0.0 4.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX75397.1 - 2e-08 33.5 4.3 1.8e-05 23.8 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX75397.1 - 3.4e-06 26.9 0.6 2.9e-05 23.9 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX75397.1 - 1.4e-05 24.2 0.3 2.1e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX75397.1 - 0.00024 21.0 0.1 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX75397.1 - 0.00083 19.4 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX75397.1 - 0.0016 17.5 0.2 0.0038 16.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KXX75397.1 - 0.0039 17.5 1.6 0.064 13.6 0.1 3.3 4 1 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX75397.1 - 0.0057 15.7 0.3 0.012 14.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 KXX75397.1 - 0.0079 16.1 0.2 0.064 13.2 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 KXX75397.1 - 0.0095 14.4 0.6 0.027 12.9 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 KXX75397.1 - 0.013 14.1 0.2 0.019 13.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX75397.1 - 0.026 14.3 0.2 0.089 12.5 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX75397.1 - 0.03 13.2 0.0 0.062 12.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_23 PF13489.1 KXX75400.1 - 8.8e-26 90.5 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX75400.1 - 1e-12 48.3 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX75400.1 - 2.3e-12 47.2 0.0 7.2e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75400.1 - 2.6e-11 43.3 0.0 7.8e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX75400.1 - 5e-11 43.1 0.0 2.9e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX75400.1 - 4.3e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX75400.1 - 9e-06 24.9 0.0 6e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KXX75400.1 - 4.4e-05 22.7 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 KXX75400.1 - 0.00059 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX75400.1 - 0.0017 17.4 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KXX75400.1 - 0.0044 17.0 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KXX75400.1 - 0.0062 15.9 0.0 0.023 14.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KXX75400.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 KXX75400.1 - 0.033 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KXX75400.1 - 0.049 12.7 0.0 0.094 11.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KXX75400.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KXX75400.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_18 PF00704.23 KXX75401.1 - 1.1e-49 169.7 0.0 1.7e-49 169.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KXX75401.1 - 5.9e-17 61.2 0.4 2.5e-07 30.4 0.4 2.7 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 KXX75401.1 - 0.089 12.4 0.0 0.24 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3142) HgmA PF04209.8 KXX75403.1 - 1.9e-170 566.8 0.0 2.4e-170 566.5 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF2695 PF10905.3 KXX75405.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) DUF4091 PF13320.1 KXX75406.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) NmrA PF05368.8 KXX75408.1 - 8.1e-09 35.0 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX75408.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TPR_12 PF13424.1 KXX75409.1 - 6.3e-36 122.1 28.0 2.7e-09 36.8 0.1 7.0 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 KXX75409.1 - 5.7e-15 54.6 36.7 0.0072 16.2 0.1 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75409.1 - 2.1e-13 49.0 16.6 0.024 14.5 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KXX75409.1 - 1.3e-12 46.5 7.9 0.023 14.4 0.0 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75409.1 - 5.4e-12 46.0 26.6 0.00021 21.8 0.1 6.4 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75409.1 - 8.3e-12 44.5 8.3 0.0009 18.8 0.1 5.5 3 2 2 5 5 5 4 TPR repeat NB-ARC PF00931.17 KXX75409.1 - 3.7e-11 42.4 0.0 6.2e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 KXX75409.1 - 5.1e-11 41.6 6.6 0.014 15.0 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75409.1 - 9.4e-08 32.0 33.2 0.025 15.2 0.2 9.0 5 3 4 9 9 8 3 Tetratricopeptide repeat AAA_16 PF13191.1 KXX75409.1 - 1.6e-07 31.4 0.0 1.6e-07 31.4 0.0 3.3 5 0 0 5 5 4 1 AAA ATPase domain TPR_8 PF13181.1 KXX75409.1 - 2.6e-06 26.8 2.9 2.6 8.0 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KXX75409.1 - 7e-06 26.1 14.8 0.46 11.0 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_22 PF13401.1 KXX75409.1 - 3.6e-05 23.9 0.0 0.00016 21.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.1 KXX75409.1 - 0.00032 20.9 11.6 0.78 10.1 0.0 5.5 4 2 2 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX75409.1 - 0.0024 17.9 2.4 0.49 10.5 0.0 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX75409.1 - 0.0093 15.8 16.1 0.5 10.2 0.1 5.3 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75409.1 - 0.01 16.1 35.1 0.12 12.8 1.2 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 KXX75409.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPR_17 PF13431.1 KXX75409.1 - 2.4 8.5 6.9 41 4.7 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat FerI PF08151.7 KXX75412.1 - 0.046 13.7 0.1 3.9 7.5 0.0 3.3 3 1 0 3 3 3 0 FerI (NUC094) domain HET PF06985.6 KXX75413.1 - 4.7e-35 120.7 0.7 7.9e-35 120.0 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ORC6 PF05460.8 KXX75414.1 - 5.6 5.9 5.6 9.1 5.2 3.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1972 PF09314.6 KXX75415.1 - 0.022 14.1 8.2 1 8.8 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1972) APOC4 PF15119.1 KXX75415.1 - 0.44 10.5 5.2 5.8 6.9 0.4 3.2 1 1 2 3 3 3 0 Apolipoprotein C4 APOBEC_C PF05240.9 KXX75415.1 - 1.8 8.0 9.4 2.7 7.4 0.4 3.9 2 1 2 4 4 4 0 APOBEC-like C-terminal domain SnoaL PF07366.7 KXX75415.1 - 4 7.0 7.7 2 7.9 0.6 2.4 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase DUF3787 PF12655.2 KXX75415.1 - 4.4 7.1 20.2 2.8 7.7 0.2 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3787) MFS_1 PF07690.11 KXX75416.1 - 6.4e-34 117.2 36.4 6.4e-34 117.2 25.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX75416.1 - 2.3e-05 22.7 6.5 3.8e-05 22.0 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KXX75417.1 - 7.4e-91 304.6 0.0 1.1e-90 303.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KXX75417.1 - 1.8e-55 187.9 1.8 2.1e-29 102.3 0.1 3.2 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KXX75417.1 - 1.8e-08 34.4 0.0 6.5e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3328 PF11807.3 KXX75418.1 - 3.2e-50 170.8 0.0 4.9e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_3 PF01494.14 KXX75419.1 - 1.6e-15 57.0 0.2 1.2e-06 27.8 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KXX75419.1 - 1.6e-05 23.9 0.0 0.00046 19.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX75419.1 - 0.00013 20.9 0.1 0.00053 18.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX75419.1 - 0.01 16.2 0.0 0.031 14.6 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX75419.1 - 0.019 14.8 0.1 0.14 12.0 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX75419.1 - 0.029 14.3 0.1 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX75419.1 - 0.06 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PGG PF13962.1 KXX75420.1 - 0.87 9.2 6.6 0.66 9.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function Trypan_PARP PF05887.6 KXX75421.1 - 0.00028 20.6 10.7 0.00051 19.8 7.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-GRF PF06839.7 KXX75421.1 - 0.04 13.8 10.8 0.62 10.0 0.3 2.4 2 0 0 2 2 2 0 GRF zinc finger Lamp PF01299.12 KXX75421.1 - 0.32 10.1 1.3 0.44 9.6 0.9 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) C1_3 PF07649.7 KXX75421.1 - 8 6.5 7.6 2.3 8.3 0.1 2.7 3 0 0 3 3 3 0 C1-like domain MFS_1 PF07690.11 KXX75422.1 - 4.3e-26 91.4 39.7 1.5e-16 60.0 4.1 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX75422.1 - 2.7e-08 32.8 8.4 2.7e-08 32.8 5.8 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Glyoxalase PF00903.20 KXX75423.1 - 6.3e-08 32.6 9.4 2.9e-06 27.2 2.7 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX75423.1 - 4.7e-07 30.3 3.4 0.0014 19.1 0.2 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KXX75423.1 - 0.022 14.7 1.2 0.41 10.6 0.2 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ketoacyl-synt PF00109.21 KXX75424.1 - 2.1e-72 243.6 0.0 3.7e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX75424.1 - 7.8e-62 208.1 0.0 2.4e-61 206.5 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KXX75424.1 - 3.4e-55 187.6 0.0 1.6e-54 185.4 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KXX75424.1 - 8.4e-46 155.9 0.0 2.4e-45 154.4 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 KXX75424.1 - 9.1e-39 133.3 0.0 1.8e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KXX75424.1 - 9.9e-34 115.7 0.3 3.2e-33 114.0 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX75424.1 - 2.3e-11 44.0 0.1 1.5e-10 41.4 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KXX75424.1 - 6.8e-11 43.1 0.0 2.5e-10 41.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KXX75424.1 - 1e-10 41.5 0.0 2.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75424.1 - 1.8e-09 37.3 0.0 1.2e-07 31.4 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX75424.1 - 1.2e-07 32.0 0.1 7.2e-07 29.6 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KXX75424.1 - 3.1e-07 29.9 0.1 0.0012 18.3 0.1 2.9 1 1 1 2 2 2 2 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX75424.1 - 5.7e-07 29.7 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KXX75424.1 - 1.5e-06 28.7 0.1 0.00019 21.9 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KXX75424.1 - 2.1e-06 27.4 0.2 5.9e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KXX75424.1 - 0.00083 18.4 2.1 0.00088 18.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KXX75424.1 - 0.00084 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX75424.1 - 0.0044 17.3 0.1 0.099 13.0 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain PCMT PF01135.14 KXX75424.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KXX75424.1 - 0.23 10.4 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FSH1 PF03959.8 KXX75425.1 - 2.7e-19 69.4 0.0 3.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX75425.1 - 0.0051 16.7 0.6 2.6 7.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Acetyltransf_10 PF13673.1 KXX75425.1 - 0.062 13.4 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.15 KXX75425.1 - 0.092 12.2 0.2 2 7.8 0.1 2.5 1 1 0 2 2 2 0 alpha/beta hydrolase fold Mannitol_dh_C PF08125.8 KXX75426.1 - 1.3e-46 158.7 0.1 1.8e-46 158.3 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KXX75426.1 - 1.1e-20 74.0 0.5 5.5e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KXX75426.1 - 0.00016 21.0 0.7 0.00052 19.4 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 KXX75426.1 - 0.036 13.6 0.6 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 KXX75426.1 - 0.085 12.3 0.2 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Coatomer_WDAD PF04053.9 KXX75427.1 - 4.3e-173 576.1 0.0 2.1e-171 570.5 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 KXX75427.1 - 6.9e-46 152.5 6.5 9.6e-10 37.9 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KXX75427.1 - 8.6e-07 27.4 2.6 0.0065 14.6 0.0 4.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KXX75427.1 - 0.00028 20.6 0.1 0.53 10.0 0.0 3.5 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 KXX75427.1 - 0.024 14.4 0.3 10 6.0 0.1 3.9 5 0 0 5 5 5 0 YmzC-like protein CRAL_TRIO PF00650.15 KXX75428.1 - 3.8e-23 81.7 0.0 5.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX75428.1 - 1.1e-11 44.6 0.1 2.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.2 KXX75429.1 - 9.4e-52 175.0 0.0 1.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KXX75429.1 - 0.017 15.3 0.1 1.5 9.0 0.0 2.8 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mod_r PF07200.8 KXX75430.1 - 3.8e-10 39.8 2.6 7.9e-10 38.8 1.8 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SH3_9 PF14604.1 KXX75431.1 - 1.3e-31 107.8 2.7 2.6e-15 55.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KXX75431.1 - 7.3e-27 92.5 3.9 5.3e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KXX75431.1 - 1.2e-16 59.9 0.0 1.1e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KXX75431.1 - 4.5e-12 45.9 0.0 7.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.19 KXX75432.1 - 2.6e-17 62.5 0.0 1.1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KXX75432.1 - 4.3e-13 48.8 0.0 8.9e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX75432.1 - 0.088 12.9 0.0 17 5.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like F-box PF00646.28 KXX75434.1 - 1.1e-06 28.0 0.3 2.9e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX75434.1 - 0.0011 18.5 1.2 0.0024 17.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like CBF PF03914.12 KXX75435.1 - 2.4e-49 166.9 0.2 8.4e-49 165.1 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family APS_kinase PF01583.15 KXX75436.1 - 1.3e-70 236.1 0.0 2.2e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.17 KXX75436.1 - 5.5e-10 39.2 0.0 1.2e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.1 KXX75436.1 - 2.7e-06 27.3 0.0 7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75436.1 - 7.9e-06 26.6 0.0 1.5e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX75436.1 - 6.4e-05 23.2 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KXX75436.1 - 0.0019 17.4 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KXX75436.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.10 KXX75437.1 - 4.3e-115 384.5 0.0 4.7e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF1996 PF09362.5 KXX75439.1 - 2e-80 269.8 0.5 2.4e-80 269.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) tRNA-synt_2b PF00587.20 KXX75440.1 - 6.6e-32 110.4 0.0 9.8e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KXX75440.1 - 5.7e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain TF_Zn_Ribbon PF08271.7 KXX75440.1 - 0.034 13.4 1.5 0.12 11.6 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Rubredoxin PF00301.15 KXX75440.1 - 0.25 11.2 1.4 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin DUF1014 PF06244.7 KXX75441.1 - 6.2e-21 74.8 10.6 1.3e-20 73.7 7.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Fungal_trans_2 PF11951.3 KXX75442.1 - 5.1e-11 41.8 0.1 5.1e-11 41.8 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75442.1 - 1.6e-06 27.8 11.2 3.6e-06 26.7 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.1 KXX75442.1 - 0.24 11.7 2.6 0.62 10.4 1.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mob1_phocein PF03637.12 KXX75443.1 - 1e-24 87.1 0.4 1.5e-24 86.5 0.3 1.2 1 0 0 1 1 1 1 Mob1/phocein family Arv1 PF04161.8 KXX75444.1 - 2.8e-25 89.4 0.3 3.3e-25 89.2 0.2 1.0 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.15 KXX75445.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain SMC_N PF02463.14 KXX75446.1 - 2.1e-69 233.1 7.2 8.1e-68 227.9 5.0 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KXX75446.1 - 4.9e-23 81.3 0.4 3.6e-22 78.5 0.1 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KXX75446.1 - 1.8e-12 47.8 6.0 5.7e-06 26.5 0.3 3.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KXX75446.1 - 3.7e-11 43.7 21.3 3.7e-11 43.7 14.7 6.8 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 KXX75446.1 - 8.4e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 KXX75446.1 - 0.00069 18.8 5.4 0.00069 18.8 3.8 8.1 4 2 3 7 7 7 3 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KXX75446.1 - 0.69 9.0 38.4 0.16 11.1 1.8 6.5 3 2 3 8 8 8 0 Reovirus sigma C capsid protein MOSC PF03473.12 KXX75447.1 - 3.5e-15 55.6 0.0 8.3e-15 54.4 0.0 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.11 KXX75447.1 - 8.5e-12 44.8 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NOT2_3_5 PF04153.13 KXX75448.1 - 1.7e-32 112.0 0.5 2.6e-32 111.5 0.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 KXX75449.1 - 1.4e-45 154.8 0.2 1.8e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KXX75449.1 - 7.4e-07 28.7 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KXX75449.1 - 0.0069 15.8 1.3 0.049 13.0 0.9 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KXX75449.1 - 0.011 16.0 0.1 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KXX75449.1 - 0.013 15.9 0.2 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 KXX75449.1 - 0.014 15.3 0.5 0.054 13.4 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KXX75449.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KXX75449.1 - 0.02 13.7 1.5 1.5 7.5 0.1 2.8 3 0 0 3 3 3 0 ArgK protein AAA_23 PF13476.1 KXX75449.1 - 0.021 15.1 0.1 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KXX75449.1 - 0.034 13.6 0.3 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KXX75449.1 - 0.035 13.5 0.2 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KXX75449.1 - 0.041 12.8 0.4 6.6 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 KXX75449.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KXX75449.1 - 0.052 13.7 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KXX75449.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KXX75449.1 - 0.1 12.5 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KXX75449.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KXX75449.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KXX75449.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KXX75449.1 - 0.19 11.3 0.7 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain CUE PF02845.11 KXX75451.1 - 6.2e-08 31.9 0.0 9.9e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain WD40 PF00400.27 KXX75452.1 - 8.7e-25 85.6 17.7 1.3e-06 28.0 0.1 6.5 5 1 1 6 6 6 6 WD domain, G-beta repeat DEAD PF00270.24 KXX75453.1 - 2.4e-41 141.0 0.2 6.6e-41 139.6 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX75453.1 - 1.2e-21 76.3 6.1 9.4e-21 73.4 0.2 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX75453.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX75453.1 - 0.11 12.6 0.1 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 KXX75454.1 - 1.4e-10 40.7 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2OG-FeII_Oxy_2 PF13532.1 KXX75455.1 - 2.1e-35 122.3 0.0 2.8e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KXX75455.1 - 6.8e-10 38.7 3.2 1.2e-09 37.9 2.2 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 KXX75455.1 - 3.9e-05 23.0 0.1 7.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain 2OG-FeII_Oxy PF03171.15 KXX75455.1 - 0.00035 20.8 0.0 0.0009 19.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KXX75456.1 - 7.3e-48 163.2 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MutS_V PF00488.16 KXX75457.1 - 1.3e-75 253.8 0.0 2e-75 253.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KXX75457.1 - 6.5e-47 159.9 0.1 1.1e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KXX75457.1 - 1.3e-30 105.7 0.0 7.5e-30 103.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KXX75457.1 - 1.6e-15 57.4 0.0 3.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KXX75457.1 - 6.2e-11 42.3 0.2 2e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_23 PF13476.1 KXX75457.1 - 0.0052 17.1 0.2 0.0052 17.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KXX75457.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KXX75457.1 - 0.077 12.9 0.2 0.077 12.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX75457.1 - 0.17 12.2 0.0 0.66 10.2 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF3461 PF11944.3 KXX75457.1 - 0.19 11.5 0.5 0.39 10.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) AAA_15 PF13175.1 KXX75457.1 - 0.42 9.6 0.0 0.81 8.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF4106 PF13388.1 KXX75457.1 - 1.4 7.8 4.3 2.5 6.9 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HET PF06985.6 KXX75458.1 - 8.5e-33 113.4 0.1 1.7e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RIO1 PF01163.17 KXX75459.1 - 6.7e-06 25.5 0.0 8.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KXX75459.1 - 2.5e-05 24.1 0.0 2.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KXX75459.1 - 0.038 13.1 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Glyoxal_oxid_N PF07250.6 KXX75459.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus CsgE PF10627.4 KXX75459.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE Fungal_trans PF04082.13 KXX75460.1 - 3.8e-09 35.8 0.1 2.9e-08 32.9 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 KXX75461.1 - 6.1e-166 552.2 0.0 8.1e-166 551.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KXX75461.1 - 6e-10 39.0 0.2 1.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KXX75461.1 - 2.9e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Epimerase PF01370.16 KXX75462.1 - 2.1e-19 69.9 0.0 2.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX75462.1 - 7.4e-08 31.4 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX75462.1 - 3.3e-05 22.9 0.0 0.00014 20.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KXX75462.1 - 0.00016 21.7 0.6 0.00075 19.5 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX75462.1 - 0.02 14.7 6.2 0.047 13.6 2.8 2.3 1 1 1 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.11 KXX75463.1 - 7.6e-33 113.6 26.2 7.6e-33 113.6 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KXX75463.1 - 1.1 9.2 4.9 0.48 10.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) SUR7 PF06687.7 KXX75464.1 - 0.0051 16.3 0.1 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family HET PF06985.6 KXX75465.1 - 5.6e-19 68.6 0.0 1.4e-18 67.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP20 PF00011.16 KXX75466.1 - 5.2e-19 68.0 0.0 8e-13 48.1 0.0 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family Alpha_GJ PF03229.8 KXX75466.1 - 0.24 11.7 13.2 0.46 10.8 9.2 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J Fer4 PF00037.22 KXX75468.1 - 3.8e-14 51.5 16.4 5.3e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KXX75468.1 - 3.8e-12 46.3 11.0 6e-12 45.7 7.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KXX75468.1 - 2.3e-10 41.0 6.8 0.0002 22.0 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KXX75468.1 - 7.2e-10 38.5 21.9 2.5e-08 33.5 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KXX75468.1 - 8.9e-10 38.6 11.0 1.7e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KXX75468.1 - 2e-09 37.1 32.6 5.6e-06 26.1 8.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KXX75468.1 - 1.1e-08 34.9 31.5 7.4e-06 25.9 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KXX75468.1 - 3.3e-08 32.9 15.0 0.00043 20.0 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KXX75468.1 - 8.6e-08 31.7 17.0 0.00051 19.7 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KXX75468.1 - 4.1e-06 26.6 13.1 0.00044 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KXX75468.1 - 5e-06 26.7 10.3 0.00046 20.4 7.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KXX75468.1 - 1.9e-05 25.0 9.9 0.0045 17.3 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KXX75468.1 - 0.01 16.2 14.9 0.32 11.4 2.9 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 KXX75468.1 - 0.018 15.5 13.1 0.32 11.5 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KXX75468.1 - 0.036 14.6 17.7 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KXX75468.1 - 0.13 12.3 4.9 0.29 11.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 KXX75469.1 - 4.4e-12 46.0 0.1 6.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KXX75469.1 - 1e-05 25.4 0.2 1.3e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 KXX75469.1 - 0.16 12.1 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) zf-CCCH PF00642.19 KXX75470.1 - 3.5e-10 39.3 8.2 3.9e-05 23.2 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KXX75470.1 - 0.18 11.8 17.5 0.25 11.3 3.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Fringe PF02434.11 KXX75471.1 - 1.1e-07 31.3 0.6 1.1e-06 28.1 0.4 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KXX75471.1 - 0.0021 17.7 4.1 0.0062 16.2 2.8 1.7 1 0 0 1 1 1 1 PAN domain Glyco_tranf_2_3 PF13641.1 KXX75472.1 - 2.2e-12 47.2 0.2 4e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KXX75472.1 - 2.3e-09 37.2 9.4 9.9e-09 35.1 6.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KXX75472.1 - 2.6e-09 36.5 0.1 5.3e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KXX75472.1 - 3.3e-06 25.7 0.4 7.1e-05 21.3 0.3 2.3 1 1 0 1 1 1 1 Chitin synthase HRXXH PF13933.1 KXX75473.1 - 1.6e-68 230.7 0.2 1.8e-68 230.6 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family HCV_NS5a_1a PF08300.8 KXX75473.1 - 0.042 13.7 0.4 0.08 12.8 0.3 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain MVL PF12151.3 KXX75473.1 - 0.75 9.5 4.1 1.7 8.3 2.8 1.6 1 1 0 1 1 1 0 Mannan-binding protein DUF423 PF04241.10 KXX75474.1 - 8.9e-18 64.0 3.7 8.1e-17 60.9 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF423) Trep_Strep PF09605.5 KXX75474.1 - 0.089 12.4 0.4 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Abhydrolase_6 PF12697.2 KXX75476.1 - 2.7e-16 60.1 3.0 3.9e-16 59.6 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX75476.1 - 1.3e-09 37.9 0.1 3.4e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX75476.1 - 0.00015 21.3 0.0 0.00096 18.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KXX75476.1 - 0.0041 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KXX75476.1 - 0.0043 16.2 0.1 0.0079 15.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.7 KXX75476.1 - 0.057 12.2 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.17 KXX75477.1 - 2e-50 171.6 0.0 2.6e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KXX75478.1 - 1.3e-60 205.0 0.0 1.7e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX75478.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KXX75478.1 - 0.00083 19.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX75478.1 - 0.00092 18.2 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX75478.1 - 0.002 17.1 0.0 0.005 15.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KXX75478.1 - 0.0041 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX75478.1 - 0.0044 16.7 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KXX75478.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX75478.1 - 0.033 13.0 2.4 0.034 13.0 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KXX75478.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KXX75478.1 - 0.16 12.0 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain But2 PF09792.4 KXX75479.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain FAD_binding_4 PF01565.18 KXX75480.1 - 4.4e-21 74.8 0.2 8.5e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75480.1 - 2.5e-05 24.1 0.1 6.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_2 PF02230.11 KXX75482.1 - 1.7e-23 83.2 0.0 5.2e-22 78.3 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX75482.1 - 1.7e-06 28.1 0.5 0.03 14.2 0.1 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX75482.1 - 2.5e-05 24.0 0.0 7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KXX75482.1 - 0.0031 16.9 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KXX75482.1 - 0.12 11.6 0.0 0.3 10.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family OB_NTP_bind PF07717.11 KXX75483.1 - 4.3e-28 97.4 0.0 1e-26 93.0 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KXX75483.1 - 4.3e-27 94.1 2.1 4.5e-27 94.0 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KXX75483.1 - 3.9e-12 45.8 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KXX75483.1 - 5.8e-12 45.5 0.5 1.3e-11 44.4 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KXX75483.1 - 1.1e-06 28.2 0.3 3e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX75483.1 - 1e-05 25.6 0.2 3.8e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KXX75483.1 - 3.2e-05 22.9 0.0 7.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KXX75483.1 - 0.004 16.8 0.2 0.014 15.1 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KXX75483.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KXX75483.1 - 0.018 14.9 0.3 0.14 12.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX75483.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KXX75483.1 - 0.073 12.2 0.1 0.2 10.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 KXX75483.1 - 0.075 13.3 0.3 0.46 10.7 0.2 2.4 1 1 0 1 1 1 0 ABC transporter Myosin_head PF00063.16 KXX75483.1 - 0.076 11.0 0.0 0.12 10.3 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) NB-ARC PF00931.17 KXX75483.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Herpes_ori_bp PF02399.10 KXX75483.1 - 0.17 9.7 0.0 0.27 9.1 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Guanylate_kin PF00625.16 KXX75484.1 - 4.6e-60 202.1 0.0 5.2e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KXX75484.1 - 4e-07 29.9 0.0 1.2e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX75484.1 - 1.1e-05 25.7 0.1 4.4e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX75484.1 - 0.00027 21.0 0.1 0.0023 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX75484.1 - 0.0013 19.5 0.1 0.0031 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KXX75484.1 - 0.0032 16.6 0.0 0.0052 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX75484.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF1895 PF08988.5 KXX75484.1 - 0.0086 16.0 0.3 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1895) AAA_28 PF13521.1 KXX75484.1 - 0.029 14.3 0.2 0.67 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX75484.1 - 0.045 14.0 0.0 0.059 13.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KXX75484.1 - 0.054 13.3 0.0 0.098 12.5 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KXX75484.1 - 0.15 12.2 0.2 0.61 10.2 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TENA_THI-4 PF03070.11 KXX75486.1 - 4.9e-12 46.0 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family QRPTase_N PF02749.11 KXX75486.1 - 0.066 13.0 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Pyr_redox_3 PF13738.1 KXX75487.1 - 8.6e-13 48.8 0.0 2.3e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KXX75487.1 - 3.6e-10 38.6 0.1 6e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KXX75487.1 - 7.3e-10 38.2 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KXX75487.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.1 KXX75488.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase ALO PF04030.9 KXX75490.1 - 1.5e-16 60.8 0.0 2.4e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KXX75490.1 - 2.3e-15 56.2 0.2 4.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FPN1 PF06963.7 KXX75491.1 - 3.2e-122 408.0 13.5 3.7e-122 407.8 9.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.2 KXX75491.1 - 0.035 13.9 1.2 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 MFS_1 like family Transgly_assoc PF04226.8 KXX75491.1 - 0.28 11.2 4.5 5.3 7.2 0.3 3.7 3 0 0 3 3 3 0 Transglycosylase associated protein Glyco_hydro_76 PF03663.9 KXX75492.1 - 2.6e-125 418.6 1.2 3.4e-125 418.2 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TBP PF00352.16 KXX75493.1 - 2.6e-58 193.3 0.0 5.7e-29 99.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KXX75493.1 - 0.0034 17.4 0.0 0.38 10.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4312 PF14189.1 KXX75493.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Sugar_tr PF00083.19 KXX75494.1 - 2.7e-69 233.8 19.6 3.3e-69 233.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75494.1 - 1.4e-26 93.0 26.5 1.5e-22 79.8 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KXX75495.1 - 3.9e-30 104.8 0.0 6.2e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.21 KXX75495.1 - 0.0042 16.9 4.2 0.0046 16.7 0.3 3.1 3 0 0 3 3 3 1 WW domain Cupin_8 PF13621.1 KXX75497.1 - 5e-41 140.8 0.0 7.9e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KXX75497.1 - 1.4e-18 67.0 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KXX75497.1 - 2.3e-16 59.2 7.8 5.4e-10 38.8 0.1 4.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KXX75497.1 - 6.8e-07 29.1 1.8 0.04 14.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 KXX75497.1 - 6e-05 23.0 7.0 0.0011 19.0 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX75497.1 - 0.0038 17.1 2.1 0.2 11.6 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Cupin_4 PF08007.7 KXX75497.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Kelch_2 PF07646.10 KXX75497.1 - 0.026 14.2 6.6 1.1 9.1 0.1 3.5 4 0 0 4 4 4 0 Kelch motif Mito_carr PF00153.22 KXX75498.1 - 1.9e-46 155.7 9.9 3.8e-18 64.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RGS PF00615.14 KXX75501.1 - 3.7e-10 39.9 0.0 5.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 KXX75502.1 - 2.2e-18 66.6 0.0 3.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAM101 PF15068.1 KXX75502.1 - 0.025 14.0 0.5 0.049 13.0 0.3 1.4 1 0 0 1 1 1 0 FAM101 family HDNR PF15115.1 KXX75503.1 - 0.054 13.4 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function with conserved HDNR motif AAA PF00004.24 KXX75505.1 - 4.1e-36 124.1 0.0 7.9e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX75505.1 - 1.9e-06 27.9 0.7 0.00033 20.6 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KXX75505.1 - 1.7e-05 23.9 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KXX75505.1 - 1.9e-05 25.4 0.1 4.6e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX75505.1 - 2.2e-05 24.6 0.1 0.0033 17.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KXX75505.1 - 8e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KXX75505.1 - 0.0006 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX75505.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX75505.1 - 0.0015 18.2 0.1 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KXX75505.1 - 0.0037 16.9 0.1 0.0095 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KXX75505.1 - 0.0066 15.2 0.0 0.0098 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KXX75505.1 - 0.0069 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KXX75505.1 - 0.0075 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KXX75505.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KXX75505.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KXX75505.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KXX75505.1 - 0.025 14.1 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KXX75505.1 - 0.026 13.9 0.2 4.2 6.7 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KXX75505.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 KXX75505.1 - 0.032 13.4 0.1 0.58 9.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_25 PF13481.1 KXX75505.1 - 0.037 13.4 0.4 0.19 11.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KXX75505.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KXX75505.1 - 0.084 12.5 0.1 0.54 9.9 0.0 2.2 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.22 KXX75505.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 KXX75505.1 - 0.11 11.7 0.2 0.24 10.5 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein Zeta_toxin PF06414.7 KXX75505.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KXX75505.1 - 0.14 11.0 0.1 0.26 10.2 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 KXX75505.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DAO PF01266.19 KXX75506.1 - 4e-47 160.8 0.0 6.6e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KXX75506.1 - 2.5e-06 26.8 0.7 4e-05 22.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX75506.1 - 3.5e-06 26.1 3.5 3e-05 23.0 2.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX75506.1 - 0.00022 21.1 0.1 0.00058 19.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX75506.1 - 0.00048 20.1 0.3 0.0019 18.2 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX75506.1 - 0.0012 18.0 0.4 0.047 12.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 KXX75506.1 - 0.0045 16.6 0.1 0.0078 15.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KXX75506.1 - 0.0056 17.0 0.4 0.017 15.5 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX75506.1 - 0.0069 14.9 0.9 0.011 14.2 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KXX75506.1 - 0.034 13.0 0.1 0.072 11.9 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KXX75506.1 - 0.053 12.5 0.2 0.22 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KXX75506.1 - 0.073 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX75506.1 - 0.074 11.9 0.1 0.16 10.8 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein LRV PF01816.12 KXX75507.1 - 0.0073 16.4 2.0 2.6 8.4 0.1 3.5 2 0 0 2 2 2 2 Leucine rich repeat variant Neisseria_TspB PF05616.8 KXX75507.1 - 4.3 5.5 4.7 6.2 5.0 3.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Mus7 PF09462.5 KXX75508.1 - 4.5e-180 600.5 0.0 6.6e-180 599.9 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family COX4 PF02936.9 KXX75509.1 - 4.9e-54 181.9 0.1 5.6e-54 181.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 KXX75509.1 - 0.073 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF1237 PF06824.6 KXX75510.1 - 1.7e-138 461.8 0.0 1.9e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Usp PF00582.21 KXX75511.1 - 8.2e-23 81.1 5.1 4.7e-21 75.4 1.6 2.7 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S7 PF00177.16 KXX75512.1 - 6.3e-23 80.9 0.0 9.1e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mito_fiss_reg PF05308.6 KXX75512.1 - 6.6 6.0 14.0 0.22 10.8 5.3 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_92 PF07971.7 KXX75513.1 - 2.2e-170 567.6 0.0 2.7e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 HECT PF00632.20 KXX75514.1 - 2e-84 283.4 0.0 3e-84 282.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KXX75514.1 - 0.0086 15.6 6.2 0.024 14.2 4.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.17 KXX75515.1 - 3.5e-81 266.8 8.6 1.8e-21 75.4 0.3 5.6 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75515.1 - 7.3e-54 179.6 1.7 4.6e-14 52.1 0.0 6.1 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75515.1 - 6.1e-40 134.8 0.3 3.8e-09 36.2 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KXX75515.1 - 4.2e-29 100.0 3.7 9.6e-29 98.8 1.7 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KXX75515.1 - 2.1e-05 24.2 0.2 6.2 6.6 0.0 4.8 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KXX75515.1 - 0.0012 19.0 0.1 6.2 7.1 0.0 3.8 3 0 0 3 3 3 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 KXX75515.1 - 0.049 13.1 1.8 7.6 6.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Nab6_mRNP_bdg PF10567.4 KXX75515.1 - 0.075 12.0 1.4 0.12 11.3 0.2 1.8 2 0 0 2 2 2 0 RNA-recognition motif DUF1237 PF06824.6 KXX75517.1 - 6e-07 28.4 0.0 7.1e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RCC1 PF00415.13 KXX75518.1 - 6.9e-24 83.8 0.1 1.9e-07 31.2 0.1 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KXX75518.1 - 2.5e-10 40.6 0.1 6.6e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75518.1 - 1.8e-08 33.7 0.2 0.012 15.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 KXX75518.1 - 2.9e-08 33.1 9.0 3.8e-07 29.5 0.8 4.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 KXX75518.1 - 1.4e-05 25.3 0.2 5.7e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75518.1 - 0.0018 17.9 0.1 0.029 14.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KXX75518.1 - 0.0084 16.3 0.1 0.11 12.7 0.0 3.1 2 1 2 4 4 4 1 Ankyrin repeats (many copies) PTPA PF03095.10 KXX75519.1 - 1e-94 317.0 0.0 1.4e-92 310.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SET PF00856.23 KXX75520.1 - 1.7e-05 25.2 0.0 0.068 13.4 0.0 2.4 2 1 0 2 2 2 2 SET domain Rad4 PF03835.10 KXX75521.1 - 1.1e-27 96.2 0.0 2.5e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KXX75521.1 - 3.3e-26 90.7 0.3 5.9e-26 89.9 0.2 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KXX75521.1 - 1.2e-21 75.9 0.0 2.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KXX75521.1 - 4.6e-11 42.8 0.1 3.4e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KXX75521.1 - 0.00056 20.1 0.3 0.0024 18.0 0.1 2.2 2 1 0 2 2 2 1 Transglutaminase-like superfamily Cwf_Cwc_15 PF04889.7 KXX75521.1 - 0.35 10.5 6.2 0.95 9.1 4.3 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HET PF06985.6 KXX75522.1 - 1.5e-35 122.4 0.1 3.4e-35 121.2 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 KXX75523.1 - 1.9e-18 66.9 0.0 3.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KXX75523.1 - 4.2e-05 23.4 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX75523.1 - 5.3e-05 23.3 0.1 0.0014 18.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 KXX75523.1 - 0.0006 20.6 0.2 0.0033 18.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain Zot PF05707.7 KXX75523.1 - 0.0017 17.8 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 KXX75523.1 - 0.0029 17.6 0.1 0.012 15.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KXX75523.1 - 0.0067 16.7 0.0 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KXX75523.1 - 0.0083 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KXX75523.1 - 0.014 15.1 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KXX75523.1 - 0.057 12.4 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KXX75523.1 - 0.081 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mito_carr PF00153.22 KXX75524.1 - 8.8e-68 224.0 4.4 1.3e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KXX75524.1 - 0.39 10.7 3.4 0.42 10.6 0.1 2.8 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family zf-CCCH PF00642.19 KXX75525.1 - 0.00059 19.4 4.7 0.00059 19.4 3.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.25 KXX75528.1 - 3.1e-38 127.6 7.9 2.4e-10 39.6 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 KXX75528.1 - 1.2e-33 115.2 3.4 2.6e-16 59.7 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX75528.1 - 4e-23 79.1 6.5 7.3e-06 25.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KXX75528.1 - 2.9e-22 78.6 6.0 5.2e-12 45.9 0.2 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX75528.1 - 1.8e-20 72.5 13.2 1.3e-08 34.7 0.2 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 KXX75528.1 - 4.7e-07 29.6 0.0 1.8e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX75528.1 - 0.00038 20.4 0.1 0.0022 17.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX75528.1 - 0.009 16.1 0.0 0.04 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX75528.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain GLTP PF08718.6 KXX75528.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Fungal_trans PF04082.13 KXX75529.1 - 5.7e-22 77.8 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KXX75530.1 - 1.4e-27 95.8 2.9 1.4e-27 95.8 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KXX75530.1 - 1e-10 41.3 0.5 2.4e-10 40.1 0.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like Gly_transf_sug PF04488.10 KXX75531.1 - 1.4e-09 38.2 0.1 2.9e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif KTSC PF13619.1 KXX75532.1 - 0.047 13.3 0.4 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 KTSC domain NicO PF03824.11 KXX75534.1 - 7e-66 222.4 7.3 1.1e-65 221.8 5.1 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein PepSY_TM_2 PF13703.1 KXX75534.1 - 2.3 8.4 13.4 0.99 9.6 0.6 4.5 4 1 0 4 4 4 0 PepSY-associated TM helix UDPG_MGDP_dh_N PF03721.9 KXX75535.1 - 8.7e-50 168.6 0.1 1.5e-34 118.9 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KXX75535.1 - 5.4e-24 84.2 0.0 1.4e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KXX75535.1 - 8.6e-23 80.5 0.0 6.5e-17 61.6 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HET PF06985.6 KXX75536.1 - 1.2e-13 51.4 0.0 1.3e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) CorA PF01544.13 KXX75538.1 - 5e-16 58.5 0.1 8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_10 PF00331.15 KXX75538.1 - 0.0068 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.20 KXX75539.1 - 5.3e-11 42.7 0.2 1.1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX75539.1 - 0.00034 20.3 0.1 0.00075 19.2 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX75539.1 - 0.00054 19.7 0.1 0.0023 17.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KXX75539.1 - 0.001 18.8 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TIP39 PF14980.1 KXX75541.1 - 0.02 14.4 0.4 0.047 13.3 0.2 1.6 1 0 0 1 1 1 0 TIP39 peptide MAPEG PF01124.13 KXX75543.1 - 4.3e-15 55.4 4.0 5.7e-15 55.0 2.8 1.2 1 0 0 1 1 1 1 MAPEG family BTP PF05232.7 KXX75543.1 - 0.0099 15.6 0.2 0.0099 15.6 0.1 2.5 2 1 1 3 3 3 1 Bacterial Transmembrane Pair family PTPLA PF04387.9 KXX75544.1 - 5.6e-54 181.9 8.3 5.6e-54 181.9 5.8 2.1 2 1 1 3 3 3 1 Protein tyrosine phosphatase-like protein, PTPLA PAP_central PF04928.12 KXX75545.1 - 2.3e-101 337.9 0.0 3e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KXX75545.1 - 1.9e-45 154.2 0.0 3.1e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KXX75545.1 - 4e-07 30.2 0.1 1.4e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Pyr_redox_2 PF07992.9 KXX75546.1 - 2.6e-26 92.7 0.0 1.2e-25 90.5 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX75546.1 - 2.2e-13 50.4 0.0 2.9e-12 46.8 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX75546.1 - 0.00016 21.8 0.1 0.99 9.4 0.1 3.0 2 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase MscS_porin PF12795.2 KXX75546.1 - 0.031 13.5 0.5 0.05 12.9 0.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Fibrinogen_aC PF12160.3 KXX75546.1 - 0.18 11.3 3.2 0.37 10.2 2.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha C domain Na_H_Exchanger PF00999.16 KXX75548.1 - 1.1e-66 224.8 38.5 1.4e-66 224.6 26.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tubulin_3 PF14881.1 KXX75549.1 - 6.8e-72 240.7 0.0 1.3e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KXX75549.1 - 8.6e-43 145.0 0.0 2e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KXX75549.1 - 6.6e-05 22.8 0.0 0.48 10.1 0.0 2.6 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain ABC_tran PF00005.22 KXX75550.1 - 3.8e-30 104.9 0.0 1.1e-29 103.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KXX75550.1 - 2.8e-25 89.2 4.8 2.8e-25 89.2 3.3 2.4 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KXX75550.1 - 0.00011 21.5 0.0 0.00028 20.1 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KXX75550.1 - 0.0033 16.6 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KXX75550.1 - 0.0062 16.5 0.0 0.65 9.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX75550.1 - 0.014 15.3 0.2 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 KXX75550.1 - 0.015 15.1 0.9 0.16 11.9 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KXX75550.1 - 0.021 14.3 0.5 0.059 12.9 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX75550.1 - 0.054 13.6 0.2 0.43 10.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain Ctr PF04145.10 KXX75550.1 - 6.4 6.8 8.3 7.9 6.5 0.0 3.3 4 0 0 4 4 4 0 Ctr copper transporter family TRAM_LAG1_CLN8 PF03798.11 KXX75551.1 - 5.5e-32 110.9 20.0 5.5e-32 110.9 13.9 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KXX75551.1 - 3.7e-24 83.9 0.0 3.7e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein PalH PF08733.5 KXX75552.1 - 1.8e-108 362.4 0.0 2.2e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 SH3_1 PF00018.23 KXX75554.1 - 1.7e-05 24.1 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX75554.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Abhydrolase_5 PF12695.2 KXX75555.1 - 1.4e-05 24.8 1.4 6.7e-05 22.6 0.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX75555.1 - 1.5e-05 24.7 0.1 2.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KXX75555.1 - 0.0003 20.7 2.3 0.00098 19.0 1.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX75555.1 - 0.0045 16.2 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KXX75555.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KXX75555.1 - 0.01 15.4 0.0 0.065 12.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KXX75555.1 - 0.02 14.5 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KXX75555.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2413 PF10310.4 KXX75555.1 - 0.11 11.2 1.4 0.16 10.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MFS_2 PF13347.1 KXX75556.1 - 4.1e-12 45.2 3.3 4.1e-12 45.2 2.3 2.9 3 0 0 3 3 3 1 MFS/sugar transport protein DUF1228 PF06779.9 KXX75556.1 - 0.022 14.8 1.3 2.9 7.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Imm-NTF2 PF15655.1 KXX75557.1 - 0.11 12.9 0.1 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 NTF2 fold immunity protein SET PF00856.23 KXX75558.1 - 4.4e-12 46.5 0.0 2.8e-11 43.9 0.0 2.2 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KXX75558.1 - 4.9e-06 26.4 0.1 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Peroxidase_2 PF01328.12 KXX75561.1 - 1.7e-32 112.3 0.1 2.2e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 KAT11 PF08214.6 KXX75562.1 - 2.1e-88 296.7 0.0 2.7e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.1 KXX75563.1 - 1.8e-30 105.5 0.0 3.9e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KXX75563.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain NMT1 PF09084.6 KXX75567.1 - 2.2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KXX75567.1 - 1.5e-06 27.6 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 KXX75567.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein FRG1 PF06229.7 KXX75568.1 - 2.6e-58 196.6 0.3 4.2e-58 195.9 0.2 1.3 1 0 0 1 1 1 1 FRG1-like family Frataxin_Cyay PF01491.11 KXX75568.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Frataxin-like domain Calmodulin_bind PF07887.6 KXX75568.1 - 0.24 10.3 2.5 0.36 9.8 1.7 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like DUF4337 PF14235.1 KXX75568.1 - 0.32 10.8 4.9 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) SRF-TF PF00319.13 KXX75569.1 - 4.8e-23 80.1 0.2 7.7e-23 79.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF59 PF01883.14 KXX75570.1 - 1.3e-06 28.3 0.0 3.6e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 KXX75571.1 - 3.8e-12 45.6 0.0 5.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 KXX75572.1 - 2.3e-28 98.9 0.2 3.4e-26 91.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KXX75572.1 - 1.8e-27 95.2 0.0 3.5e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KXX75572.1 - 3.8e-18 65.1 0.0 1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX75572.1 - 3.3e-08 33.5 0.1 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KXX75572.1 - 8e-07 28.8 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX75572.1 - 0.026 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Thiolase_N PF00108.18 KXX75573.1 - 4e-94 314.4 0.6 4e-94 314.4 0.4 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX75573.1 - 5.1e-46 155.0 0.2 1.4e-45 153.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KXX75573.1 - 0.001 18.6 1.4 0.001 18.6 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KXX75573.1 - 0.43 10.2 3.6 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.27 KXX75574.1 - 5.5e-12 45.0 0.5 0.012 15.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat FAD_binding_2 PF00890.19 KXX75576.1 - 5.6e-86 288.9 0.9 6.8e-86 288.7 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KXX75576.1 - 1.3e-21 76.1 0.2 3.7e-20 71.5 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KXX75576.1 - 4.5e-13 48.8 2.1 2.6e-12 46.3 1.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KXX75576.1 - 6.4e-10 38.6 0.4 2.5e-09 36.7 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX75576.1 - 2.5e-09 37.0 2.4 4.9e-08 32.8 0.4 3.2 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX75576.1 - 3.9e-08 33.4 0.0 3.3e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX75576.1 - 4.4e-06 25.4 1.7 0.0047 15.4 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 KXX75576.1 - 5.1e-05 22.4 0.8 0.01 14.9 0.2 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KXX75576.1 - 0.00023 20.1 1.8 0.11 11.3 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KXX75576.1 - 0.0016 17.5 0.2 0.17 10.9 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KXX75576.1 - 0.0021 17.1 2.9 0.0074 15.3 2.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KXX75576.1 - 0.021 14.6 0.3 0.19 11.5 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX75576.1 - 0.055 13.5 1.1 0.11 12.5 0.8 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX75576.1 - 0.57 10.6 4.5 2.1 8.8 1.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KXX75577.1 - 3.2e-123 411.6 19.6 3.7e-123 411.4 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75577.1 - 2.3e-25 89.0 58.2 3.1e-24 85.3 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromate_transp PF02417.10 KXX75578.1 - 3.7e-37 127.5 38.4 1.9e-28 99.1 7.6 3.9 3 1 0 3 3 3 2 Chromate transporter PAH PF02671.16 KXX75579.1 - 2.5e-41 139.0 1.9 2e-17 62.5 0.6 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KXX75579.1 - 5.6e-38 128.7 0.1 2e-37 127.0 0.0 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor HEPN PF05168.9 KXX75579.1 - 0.0042 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 HEPN domain DUF1777 PF08648.7 KXX75579.1 - 1.5 8.5 23.2 0.035 13.8 11.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Glyco_hydro_31 PF01055.21 KXX75580.1 - 5.5e-155 516.5 2.0 7.2e-155 516.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 KXX75580.1 - 0.0076 15.4 0.2 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 DUF4448 PF14610.1 KXX75581.1 - 8.3e-37 126.5 0.2 2.9e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) 2OG-FeII_Oxy PF03171.15 KXX75582.1 - 0.039 14.2 0.0 0.095 12.9 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Synapsin_N PF10581.4 KXX75582.1 - 0.3 10.9 2.1 2.2 8.1 0.2 2.3 2 0 0 2 2 2 0 Synapsin N-terminal NAD_binding_2 PF03446.10 KXX75583.1 - 6e-31 107.4 0.0 7.5e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KXX75583.1 - 7.4e-10 38.9 0.2 1.3e-09 38.1 0.2 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KXX75583.1 - 3.8e-05 24.0 0.0 0.00022 21.5 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KXX75583.1 - 0.036 13.2 0.0 0.092 11.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMD PF02627.15 KXX75584.1 - 4.1e-16 58.5 0.5 3.6e-07 29.9 0.0 2.6 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family ADH_N PF08240.7 KXX75585.1 - 6.4e-16 58.0 0.0 2.2e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX75585.1 - 1.2e-13 50.7 0.4 1.2e-13 50.7 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KXX75585.1 - 0.0025 18.3 0.5 0.0071 16.9 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75585.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Orthoreo_P17 PF07272.6 KXX75586.1 - 0.06 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus P17 protein NAD_binding_2 PF03446.10 KXX75587.1 - 2.6e-33 115.1 0.9 4.1e-33 114.5 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KXX75587.1 - 7.1e-24 84.1 0.0 1.5e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KXX75587.1 - 2.7e-05 24.5 0.0 6.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KXX75587.1 - 0.028 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KXX75587.1 - 0.036 14.5 0.0 0.077 13.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 KXX75587.1 - 0.044 13.4 0.1 0.044 13.4 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.2 KXX75588.1 - 5.2e-05 22.8 0.0 9.5e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX75588.1 - 0.001 18.7 5.5 0.0037 16.9 3.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KXX75588.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX75589.1 - 3.3e-06 26.8 0.6 8.1e-06 25.6 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily 4HBT_3 PF13622.1 KXX75590.1 - 0.004 16.9 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.17 KXX75592.1 - 8.6e-50 169.5 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2786 PF10979.3 KXX75593.1 - 0.046 13.4 0.1 0.046 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Fungal_trans_2 PF11951.3 KXX75594.1 - 2.6e-06 26.3 0.1 9.6e-06 24.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF706 PF05153.10 KXX75595.1 - 4.4e-123 409.5 0.0 5.4e-123 409.2 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) Sugar_tr PF00083.19 KXX75596.1 - 1.3e-77 261.3 20.1 1.5e-77 261.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75596.1 - 6.8e-12 44.7 36.2 3.8e-09 35.7 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IPP-2 PF04979.9 KXX75597.1 - 8.8e-11 42.1 12.2 1.5e-06 28.5 1.1 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) K_channel_TID PF07941.6 KXX75598.1 - 0.02 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF2076 PF09849.4 KXX75598.1 - 0.053 13.5 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Thymidylate_kin PF02223.12 KXX75599.1 - 5.3e-42 143.3 0.0 1.6e-40 138.4 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 KXX75599.1 - 0.00012 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KXX75599.1 - 0.0013 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 KXX75599.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RepB PF07506.6 KXX75602.1 - 0.064 13.1 0.9 2.9 7.7 0.0 2.9 3 0 0 3 3 3 0 RepB plasmid partitioning protein Ribosomal_L27 PF01016.14 KXX75603.1 - 2.4e-24 84.9 0.2 4.5e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein TAFII28 PF04719.9 KXX75604.1 - 1e-21 76.5 0.0 1.9e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region MRC1 PF09444.5 KXX75604.1 - 0.059 13.7 0.4 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 MRC1-like domain GTP_cyclohydroI PF01227.17 KXX75605.1 - 1.5e-73 245.8 0.7 2e-73 245.5 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KXX75605.1 - 0.0038 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 KXX75605.1 - 0.085 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CMD PF02627.15 KXX75606.1 - 4.9e-20 71.1 0.1 9.2e-20 70.2 0.1 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MetJ PF01340.15 KXX75606.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met Apo-repressor, MetJ DUF159 PF02586.9 KXX75607.1 - 3.3e-58 196.6 0.0 4.2e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Amidase_6 PF12671.2 KXX75607.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative amidase domain RNA_pol_Rpb1_5 PF04998.12 KXX75608.1 - 3.7e-88 295.3 0.5 6.6e-88 294.5 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KXX75608.1 - 5.7e-83 278.9 0.0 8.7e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KXX75608.1 - 9e-67 224.1 0.0 2e-66 223.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KXX75608.1 - 1.2e-35 122.5 0.1 9.2e-35 119.6 0.0 2.5 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KXX75608.1 - 3.1e-32 110.5 0.0 9.3e-32 108.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Orbi_NS1 PF01718.11 KXX75609.1 - 0.12 10.4 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Shisa PF13908.1 KXX75610.1 - 0.12 12.5 0.2 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3166 PF11365.3 KXX75611.1 - 0.044 14.2 0.3 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DUF3896 PF13035.1 KXX75611.1 - 0.049 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) DDHD PF02862.12 KXX75613.1 - 3.1e-70 236.5 0.9 1.9e-68 230.6 0.0 2.7 2 1 0 2 2 2 1 DDHD domain DUF935 PF06074.7 KXX75613.1 - 0.0095 14.6 0.7 0.0095 14.6 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF935) Abhydrolase_5 PF12695.2 KXX75613.1 - 0.043 13.5 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KXX75613.1 - 0.19 11.1 0.0 0.56 9.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-RING_2 PF13639.1 KXX75614.1 - 0.00029 20.6 3.0 0.00029 20.6 2.1 1.9 2 0 0 2 2 2 1 Ring finger domain Ank PF00023.25 KXX75614.1 - 0.0011 18.6 0.0 0.036 13.8 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 KXX75614.1 - 0.0023 18.2 0.1 0.016 15.5 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX75614.1 - 0.011 15.9 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat zf-C3HC4_2 PF13923.1 KXX75614.1 - 0.045 13.7 3.4 0.045 13.7 2.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KXX75614.1 - 0.67 9.5 3.2 0.27 10.8 0.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KXX75614.1 - 5.1 6.9 7.5 25 4.6 5.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX75614.1 - 5.6 6.9 8.3 0.41 10.5 2.4 1.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Iso_dh PF00180.15 KXX75615.1 - 4.7e-120 400.6 0.0 5.6e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.8 KXX75615.1 - 0.04 13.4 1.3 0.04 13.4 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Peptidase_S8 PF00082.17 KXX75616.1 - 2.9e-52 177.5 2.6 4.5e-52 176.9 1.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KXX75616.1 - 1.4e-27 95.2 0.4 2.8e-27 94.3 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Baculo_p26 PF04766.7 KXX75616.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein PX PF00787.19 KXX75617.1 - 1.8e-20 72.8 0.2 4.1e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KXX75617.1 - 4.2e-14 52.3 4.8 9.3e-08 31.6 1.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KXX75617.1 - 3.2e-10 39.9 0.5 8.6e-10 38.5 0.3 1.6 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 KXX75617.1 - 0.00034 20.2 5.1 0.00057 19.5 0.1 2.1 2 0 0 2 2 2 1 IncA protein DUF3140 PF11338.3 KXX75617.1 - 0.0035 17.4 1.0 0.0081 16.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) Reo_sigmaC PF04582.7 KXX75617.1 - 0.011 14.9 0.5 0.018 14.2 0.1 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KXX75617.1 - 0.017 15.0 0.9 0.63 9.9 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 KXX75617.1 - 0.056 11.2 1.7 3.6 5.3 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 KXX75617.1 - 0.33 10.7 2.0 0.45 10.2 0.2 2.0 2 0 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.15 KXX75617.1 - 0.57 9.9 9.0 0.97 9.2 0.8 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF4404 PF14357.1 KXX75617.1 - 0.72 10.3 5.9 5.4 7.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) eIF3_subunit PF08597.5 KXX75617.1 - 1.9 8.0 9.4 0.18 11.3 2.6 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Spc7 PF08317.6 KXX75617.1 - 3.3 6.2 5.8 2.4 6.7 1.3 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KXX75617.1 - 5.1 6.0 6.7 1.1 8.1 0.3 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 HSCB_C PF07743.8 KXX75617.1 - 8.9 6.8 9.1 4.2 7.9 0.4 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain LETM1 PF07766.8 KXX75618.1 - 2.6e-110 367.6 1.4 4e-110 367.0 1.0 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KXX75618.1 - 2.4e-06 26.8 0.2 0.0099 15.3 0.0 3.6 3 0 0 3 3 3 2 SAP domain ADK PF00406.17 KXX75619.1 - 2.9e-38 131.0 0.0 3.3e-21 75.7 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KXX75619.1 - 5e-15 54.8 0.0 1.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KXX75619.1 - 7.1e-05 23.1 0.0 0.00095 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75619.1 - 0.00085 20.1 0.0 0.002 18.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX75619.1 - 0.0012 18.7 0.0 0.064 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX75619.1 - 0.059 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_76 PF03663.9 KXX75620.1 - 4.5e-21 75.6 5.3 3.2e-12 46.5 0.0 4.1 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 tRNA-synt_1b PF00579.20 KXX75621.1 - 1.9e-57 194.5 0.0 2.4e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Abhydrolase_6 PF12697.2 KXX75622.1 - 3.6e-18 66.2 0.0 4.3e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX75622.1 - 1.4e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX75622.1 - 3.9e-05 23.4 0.0 0.0002 21.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KXX75622.1 - 8.2e-05 21.2 0.1 0.00014 20.4 0.0 1.4 2 0 0 2 2 2 1 Ndr family CH PF00307.26 KXX75623.1 - 1.9e-58 195.1 0.0 4.2e-15 55.7 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KXX75623.1 - 3.9e-06 26.9 0.1 0.0001 22.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KXX75623.1 - 0.002 17.3 0.2 0.62 9.5 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KXX75623.1 - 0.062 13.2 2.0 0.52 10.3 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain CAMSAP_CH PF11971.3 KXX75623.1 - 0.08 12.6 0.0 25 4.5 0.0 3.2 4 0 0 4 4 4 0 CAMSAP CH domain zf-Tim10_DDP PF02953.10 KXX75624.1 - 2.3e-19 68.4 2.5 2.6e-19 68.2 1.7 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KXX75624.1 - 0.0011 18.4 2.2 0.0016 17.8 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 KXX75625.1 - 3.3e-63 213.4 0.0 6.1e-61 206.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KXX75625.1 - 6.8e-10 38.6 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KXX75625.1 - 1.4e-06 27.6 0.1 0.0011 18.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) PH_6 PF15406.1 KXX75626.1 - 1.4e-47 160.4 4.5 1.4e-47 160.4 3.1 4.4 4 1 2 6 6 6 1 Pleckstrin homology domain PH PF00169.24 KXX75626.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KXX75626.1 - 0.14 11.7 0.0 0.14 11.7 0.0 3.9 4 0 0 4 4 4 0 Pleckstrin homology domain PBP1_TM PF14812.1 KXX75626.1 - 0.23 11.8 8.8 4.3 7.7 1.2 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4598 PF15370.1 KXX75626.1 - 7.7 6.8 15.1 4.3 7.6 3.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) HATPase_c PF02518.21 KXX75627.1 - 1.6e-22 79.3 0.0 3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KXX75627.1 - 3.1e-17 62.5 0.3 2.7e-13 49.9 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.1 KXX75627.1 - 4.1e-11 43.1 0.0 2.9e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KXX75627.1 - 1.3e-08 34.8 0.0 0.00014 21.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KXX75627.1 - 6.9e-07 29.1 1.9 1.2e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KXX75627.1 - 5.1e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 KXX75627.1 - 0.0036 17.8 0.0 0.94 9.9 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 KXX75627.1 - 0.0057 16.4 0.0 0.026 14.4 0.0 2.2 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.1 KXX75627.1 - 0.012 15.6 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 GAF domain PG_binding_1 PF01471.13 KXX75628.1 - 7.9e-05 22.5 0.0 0.081 12.9 0.0 3.5 3 0 0 3 3 3 2 Putative peptidoglycan binding domain CLTH PF10607.4 KXX75629.1 - 5.5e-29 100.7 0.0 1.2e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KXX75629.1 - 1.7e-15 56.4 2.7 3.2e-15 55.5 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KXX75629.1 - 0.00022 20.9 1.9 0.00036 20.2 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KXX75629.1 - 0.0014 17.8 0.1 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 KXX75629.1 - 0.0022 17.9 2.5 0.0037 17.2 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX75629.1 - 0.0024 17.4 1.2 0.0037 16.8 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Flagellin_C PF00700.16 KXX75629.1 - 0.024 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region zf-RING_5 PF14634.1 KXX75629.1 - 0.034 13.8 1.6 0.055 13.2 1.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX75629.1 - 0.06 13.2 3.0 0.11 12.3 2.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_16 PF13432.1 KXX75629.1 - 0.19 12.4 5.6 3.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KXX75629.1 - 0.35 10.5 2.9 0.63 9.7 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KXX75630.1 - 5.3e-16 58.0 0.0 8.3e-16 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75630.1 - 9.7e-11 41.4 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75630.1 - 2.2e-09 37.0 0.0 3.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX75630.1 - 0.032 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Clr5 PF14420.1 KXX75631.1 - 5.6e-21 74.1 0.8 8.4e-20 70.4 0.1 2.7 3 0 0 3 3 3 1 Clr5 domain Sigma70_ner PF04546.8 KXX75631.1 - 0.87 9.1 9.1 2.2 7.8 6.3 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KXX75631.1 - 2.7 7.1 10.4 4.2 6.5 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 KXX75631.1 - 2.9 7.5 7.5 8.1 6.1 5.2 1.7 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 KXX75631.1 - 4.7 4.9 13.3 7.7 4.3 9.2 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 KXX75632.1 - 1.5e-08 34.5 0.0 1.5e-08 34.5 0.0 4.4 3 2 2 5 5 5 1 PPP4R2 Spt20 PF12090.3 KXX75632.1 - 0.013 14.8 0.9 0.013 14.8 0.6 2.9 3 1 0 3 3 3 0 Spt20 family Amidase PF01425.16 KXX75633.1 - 8.9e-70 235.7 0.2 1.4e-69 235.0 0.2 1.2 1 0 0 1 1 1 1 Amidase Troponin PF00992.15 KXX75634.1 - 0.15 12.0 8.9 5.1 7.1 3.7 2.2 2 0 0 2 2 2 0 Troponin AAA_23 PF13476.1 KXX75635.1 - 7.4e-24 85.1 9.3 7.4e-24 85.1 6.4 8.1 1 1 1 2 2 2 1 AAA domain SbcCD_C PF13558.1 KXX75635.1 - 9.5e-12 44.6 0.0 3.2e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KXX75635.1 - 1e-08 35.5 15.3 1.6e-06 28.2 1.3 3.9 3 2 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KXX75635.1 - 3.2e-08 33.0 0.0 1.6e-05 24.1 0.0 6.0 4 1 1 6 6 6 2 AAA ATPase domain SMC_N PF02463.14 KXX75635.1 - 2.9e-07 29.9 0.0 2.9e-07 29.9 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 KXX75635.1 - 1.8e-06 26.7 4.4 0.00043 18.8 1.7 7.3 2 1 4 7 7 7 4 AAA domain AAA_29 PF13555.1 KXX75635.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KXX75635.1 - 0.015 14.9 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KXX75635.1 - 0.057 13.7 0.0 0.057 13.7 0.0 7.5 4 3 0 4 4 4 0 ABC transporter CRPA PF05745.6 KXX75636.1 - 0.091 12.5 6.1 0.54 10.0 0.1 3.2 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4064 PF13273.1 KXX75636.1 - 0.41 10.7 16.2 1.2 9.2 4.2 4.0 2 2 0 3 3 3 0 Protein of unknown function (DUF4064) PsbI PF02532.9 KXX75636.1 - 8.4 6.1 8.4 0.51 10.0 0.3 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) FAD-oxidase_C PF02913.14 KXX75637.1 - 5.5e-59 199.4 0.1 8.6e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KXX75637.1 - 4.7e-38 129.7 0.0 9.1e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KXX75638.1 - 6.6e-12 45.6 0.0 1.5e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX75638.1 - 0.004 16.8 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_114 PF03537.8 KXX75641.1 - 1.2e-08 34.5 0.1 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 HET PF06985.6 KXX75642.1 - 8.2e-18 64.9 0.0 2.7e-17 63.2 0.0 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DZR PF12773.2 KXX75642.1 - 0.067 13.0 2.7 0.32 10.8 2.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon Glyoxalase PF00903.20 KXX75643.1 - 0.0046 16.9 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX75643.1 - 0.033 14.8 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain HET PF06985.6 KXX75644.1 - 0.0012 19.0 0.1 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF607 PF04678.8 KXX75645.1 - 1.2e-38 132.8 2.8 1.6e-38 132.4 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function, DUF607 DUF2968 PF11180.3 KXX75645.1 - 0.033 13.5 1.9 4.5 6.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Acetyltransf_8 PF13523.1 KXX75646.1 - 2.2e-37 128.2 0.1 3.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DSPc PF00782.15 KXX75647.1 - 1.1e-17 63.8 0.1 2.3e-09 36.9 0.1 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain ADH_zinc_N_2 PF13602.1 KXX75647.1 - 0.034 15.0 0.0 2.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KXX75647.1 - 0.075 12.0 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain Vfa1 PF08432.5 KXX75648.1 - 7.5e-59 198.8 18.9 8.4e-59 198.6 13.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 KXX75648.1 - 0.34 9.4 8.4 0.41 9.1 5.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 KXX75648.1 - 0.37 10.1 21.1 0.46 9.8 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KXX75648.1 - 0.4 8.6 18.8 0.45 8.4 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.4 KXX75648.1 - 0.47 10.7 14.0 0.59 10.4 9.7 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Astro_capsid PF03115.9 KXX75648.1 - 0.56 8.3 8.3 0.65 8.1 5.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Ycf1 PF05758.7 KXX75648.1 - 2.5 5.6 13.7 3 5.4 9.5 1.1 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 KXX75648.1 - 3.3 5.4 13.1 4 5.1 9.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2201_N PF13203.1 KXX75648.1 - 4.5 6.3 10.4 5.6 6.0 7.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP11 PF06644.6 KXX75648.1 - 4.7 6.6 14.5 6.1 6.2 10.1 1.1 1 0 0 1 1 1 0 ATP11 protein DUF4407 PF14362.1 KXX75648.1 - 9.5 5.0 11.3 12 4.7 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rtt106 PF08512.7 KXX75649.1 - 1.9e-26 91.8 0.0 7.6e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like zf-C2H2_4 PF13894.1 KXX75650.1 - 0.00018 21.5 24.0 0.044 14.1 2.2 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX75650.1 - 0.011 16.0 1.3 0.011 16.0 0.9 3.5 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.21 KXX75650.1 - 0.023 15.0 26.0 0.11 12.8 2.0 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KXX75650.1 - 5.3 7.3 13.8 0.48 10.6 2.9 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding Alpha_L_fucos PF01120.12 KXX75651.1 - 3.4e-27 95.2 0.0 6.7e-27 94.2 0.0 1.4 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 KXX75651.1 - 1.7e-09 37.6 0.4 7.2e-09 35.5 0.0 2.2 2 1 1 3 3 3 1 F5/8 type C domain CVNH PF08881.5 KXX75652.1 - 3.1e-31 107.6 0.0 3.5e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Methyltransf_23 PF13489.1 KXX75653.1 - 1.8e-22 79.7 0.0 2.6e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX75653.1 - 1.9e-08 34.8 0.0 1.6e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX75653.1 - 1.7e-07 30.9 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX75653.1 - 4e-07 30.4 0.0 7.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX75653.1 - 1e-06 29.1 0.0 6.6e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX75653.1 - 0.00066 18.8 0.0 0.013 14.6 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KXX75653.1 - 0.001 18.6 0.1 0.028 13.9 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KXX75653.1 - 0.0019 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KXX75653.1 - 0.0087 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KXX75653.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 KXX75653.1 - 0.094 11.8 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 KXX75653.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 KXX75654.1 - 3e-56 190.9 32.9 3e-51 174.4 17.4 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KXX75654.1 - 3.4e-10 39.1 27.6 6.1e-10 38.3 19.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.12 KXX75655.1 - 8.4e-22 77.9 0.0 1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.23 KXX75656.1 - 1.8e-06 28.3 0.0 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 SET domain MMR_HSR1_C PF08438.5 KXX75657.1 - 1.4e-32 112.1 0.0 2.9e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KXX75657.1 - 1.6e-14 53.8 0.0 3.1e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX75657.1 - 1.8e-05 24.0 0.0 0.00053 19.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KXX75657.1 - 0.0075 16.1 1.6 0.17 11.7 0.3 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KXX75657.1 - 0.011 15.1 0.4 0.64 9.4 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KXX75657.1 - 0.019 15.2 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 KXX75657.1 - 0.033 13.2 0.1 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 KXX75657.1 - 0.093 11.8 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Fungal_trans PF04082.13 KXX75659.1 - 1.3e-31 109.3 0.2 2.9e-31 108.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75659.1 - 1.1e-08 34.8 14.6 1.9e-08 34.0 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIG-F PF06699.6 KXX75660.1 - 9.9e-59 198.4 3.4 1.2e-58 198.1 2.4 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F YjgP_YjgQ PF03739.9 KXX75660.1 - 0.12 11.1 0.3 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Bacteriocin_IIc PF10439.4 KXX75660.1 - 3.5 7.8 11.2 1.7 8.8 3.3 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Translin PF01997.11 KXX75661.1 - 2.9e-47 160.8 0.0 3.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KXX75661.1 - 0.043 13.5 0.1 0.26 11.0 0.0 2.1 2 1 0 2 2 2 0 GMP synthase C terminal domain DCX PF03607.12 KXX75661.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Doublecortin Pmp3 PF01679.12 KXX75662.1 - 7e-26 89.6 4.5 7.7e-26 89.5 3.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 KXX75662.1 - 0.039 13.6 0.5 0.039 13.6 0.3 1.6 2 0 0 2 2 2 0 Conserved TM helix CN_hydrolase PF00795.17 KXX75663.1 - 5.5e-25 87.7 0.0 8.7e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KXX75663.1 - 2.4e-10 39.7 0.0 1e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KXX75663.1 - 0.07 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase NACHT PF05729.7 KXX75664.1 - 1.1e-06 28.3 0.2 1.1e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KXX75664.1 - 3.7e-06 27.0 0.0 1.8e-05 24.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX75664.1 - 0.00071 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KXX75664.1 - 0.0019 17.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KXX75664.1 - 0.003 18.3 0.1 0.022 15.6 0.0 2.5 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.17 KXX75664.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 KXX75664.1 - 0.0076 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 KXX75664.1 - 0.009 16.3 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KXX75664.1 - 0.0099 15.6 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KXX75664.1 - 0.012 15.9 0.7 0.042 14.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.1 KXX75664.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KXX75664.1 - 0.015 15.2 0.1 0.057 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KXX75664.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KXX75664.1 - 0.042 12.7 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 KXX75664.1 - 0.043 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KXX75664.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 KXX75664.1 - 0.074 11.8 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 KXX75664.1 - 0.088 12.3 0.1 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KXX75664.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.18 KXX75664.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2075 PF09848.4 KXX75664.1 - 0.21 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KXX75664.1 - 0.22 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KXX75664.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIG-F PF06699.6 KXX75665.1 - 9.9e-59 198.4 3.4 1.2e-58 198.1 2.4 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F YjgP_YjgQ PF03739.9 KXX75665.1 - 0.12 11.1 0.3 0.13 10.9 0.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Bacteriocin_IIc PF10439.4 KXX75665.1 - 3.5 7.8 11.2 1.7 8.8 3.3 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Translin PF01997.11 KXX75666.1 - 2.9e-47 160.8 0.0 3.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KXX75666.1 - 0.043 13.5 0.1 0.26 11.0 0.0 2.1 2 1 0 2 2 2 0 GMP synthase C terminal domain DCX PF03607.12 KXX75666.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Doublecortin Ribosomal_L22e PF01776.12 KXX75667.1 - 9.3e-46 154.4 0.2 1.1e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mito_carr PF00153.22 KXX75668.1 - 3.6e-55 183.6 0.4 2.5e-19 68.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MARVEL PF01284.18 KXX75670.1 - 1.5e-07 31.3 9.7 5.5e-07 29.5 7.0 1.7 1 1 0 1 1 1 1 Membrane-associating domain adh_short PF00106.20 KXX75671.1 - 1.7e-28 99.6 1.6 2.3e-28 99.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX75671.1 - 5.3e-25 88.5 0.0 6.3e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX75671.1 - 8.6e-13 48.3 0.7 1.2e-12 47.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX75671.1 - 0.00023 20.6 0.3 0.012 15.0 0.2 2.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CABS1 PF15367.1 KXX75671.1 - 0.0065 15.3 0.0 0.0089 14.9 0.0 1.1 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 AdoHcyase_NAD PF00670.16 KXX75671.1 - 0.052 13.3 0.8 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4470 PF14737.1 KXX75673.1 - 9.7e-22 76.6 0.0 2.3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KXX75673.1 - 4.2e-11 42.5 11.8 9.1e-11 41.4 8.2 1.6 1 0 0 1 1 1 1 MYND finger WSC PF01822.14 KXX75674.1 - 1.2e-13 50.7 9.5 2.3e-13 49.8 6.6 1.4 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 KXX75674.1 - 8.5e-05 21.7 0.9 0.00016 20.8 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3042 PF11240.3 KXX75674.1 - 0.039 13.7 3.4 0.12 12.1 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) DUF1517 PF07466.6 KXX75674.1 - 0.39 9.6 2.4 0.5 9.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) HET PF06985.6 KXX75675.1 - 1.3e-25 90.1 0.0 2.5e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.1 KXX75676.1 - 1.3e-08 34.6 11.2 0.00027 21.0 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KXX75676.1 - 5.2e-08 32.7 21.2 0.00024 21.2 3.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX75676.1 - 0.18 12.2 19.8 2.4 8.7 1.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3767 PF12597.3 KXX75678.1 - 3e-34 117.1 8.7 1.2e-33 115.2 6.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) Pex14_N PF04695.8 KXX75678.1 - 0.0055 16.7 3.9 0.0055 16.7 2.7 2.0 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1206 PF06724.6 KXX75678.1 - 0.044 13.5 0.9 0.11 12.2 0.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) 5TM-5TMR_LYT PF07694.7 KXX75678.1 - 0.15 11.4 0.2 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Ctr PF04145.10 KXX75678.1 - 0.21 11.6 8.3 1.5 8.8 1.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF4337 PF14235.1 KXX75678.1 - 1.3 8.8 10.3 15 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) IncA PF04156.9 KXX75678.1 - 2.4 7.6 7.2 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein Med15 PF09606.5 KXX75678.1 - 3.8 5.5 22.6 4.7 5.2 15.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TCP PF03634.8 KXX75678.1 - 8.5 6.7 16.3 3.3 8.1 1.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF1744 PF08490.7 KXX75679.1 - 2.3e-159 530.2 0.0 3.3e-159 529.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KXX75679.1 - 4.2e-63 213.1 0.3 6.6e-63 212.5 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KXX75679.1 - 2e-21 76.3 0.0 6.5e-21 74.6 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KXX75679.1 - 1.9e-09 37.3 0.2 4.6e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KXX75679.1 - 3e-05 23.8 0.0 9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol3_alpha PF07733.7 KXX75679.1 - 0.088 11.2 0.0 0.18 10.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit UL2 PF08196.6 KXX75680.1 - 0.1 12.3 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 UL2 protein Sporozoite_P67 PF05642.6 KXX75681.1 - 1.4 6.6 6.9 1.8 6.3 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lamp PF01299.12 KXX75681.1 - 3.9 6.5 6.9 5.4 6.0 4.8 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) ECH PF00378.15 KXX75684.1 - 5.5e-47 159.9 0.0 9.7e-44 149.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Tyrosinase PF00264.15 KXX75686.1 - 2e-22 80.4 0.0 2.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Cellulase PF00150.13 KXX75689.1 - 3.1e-21 75.8 1.3 7.2e-21 74.6 0.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KXX75689.1 - 0.00035 20.1 3.2 0.00067 19.2 2.2 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain FadR_C PF07840.7 KXX75689.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 FadR C-terminal domain DUF4360 PF14273.1 KXX75691.1 - 8.4e-18 64.6 0.8 1.1e-17 64.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Alpha-amylase PF00128.19 KXX75692.1 - 1.5e-22 80.4 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KXX75692.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Iso_dh PF00180.15 KXX75693.1 - 9.5e-79 264.8 0.0 1.1e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Thioredoxin_7 PF13899.1 KXX75695.1 - 1.6e-13 50.4 0.1 3.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 KXX75695.1 - 3.4e-08 33.4 0.0 1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KXX75695.1 - 1.3e-07 31.0 0.3 3.2e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredox_DsbH PF03190.10 KXX75695.1 - 0.0044 16.7 0.1 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KXX75695.1 - 0.051 13.7 0.2 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Pol_alpha_B_N PF08418.5 KXX75695.1 - 0.16 11.4 1.6 0.18 11.3 0.2 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 KXX75696.1 - 1.3e-69 234.2 0.0 2.1e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75696.1 - 1.6e-50 171.6 0.0 2.7e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX75696.1 - 0.00083 18.4 0.0 0.0075 15.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Ecm29 PF13001.2 KXX75698.1 - 1.5e-123 412.9 0.0 1.4e-121 406.4 0.0 2.5 1 1 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KXX75698.1 - 0.00058 19.7 5.1 0.77 10.0 0.0 6.9 8 0 0 8 8 8 1 HEAT repeat RRM_1 PF00076.17 KXX75699.1 - 3.5e-45 151.5 0.0 1.5e-16 59.8 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75699.1 - 7.3e-24 83.5 0.0 5.8e-10 39.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75699.1 - 4.4e-22 77.6 0.0 1.2e-08 34.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX75699.1 - 2.1e-06 27.5 0.0 0.00014 21.6 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KXX75699.1 - 7.2e-05 22.4 0.0 0.0032 17.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Peptidase_C48 PF02902.14 KXX75700.1 - 1.5e-30 106.4 0.0 2.5e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 KXX75701.1 - 7.1e-26 89.1 6.2 6.3e-08 32.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KXX75701.1 - 0.0039 15.3 0.1 0.061 11.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ndufs5 PF10200.4 KXX75702.1 - 0.0002 21.3 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 KXX75702.1 - 0.0027 17.6 0.2 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KXX75702.1 - 0.014 15.3 0.2 0.028 14.3 0.1 1.6 1 1 0 1 1 1 0 CHCH domain DUF3128 PF11326.3 KXX75702.1 - 0.041 14.0 1.4 0.1 12.6 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.11 KXX75702.1 - 0.092 12.6 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Pkinase PF00069.20 KXX75703.1 - 3.2e-09 36.3 0.0 5.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75703.1 - 0.0012 18.0 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX75703.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX75703.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_6 PF08030.7 KXX75704.1 - 3.4e-05 23.8 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KXX75704.1 - 0.00069 20.1 0.0 0.4 11.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KXX75704.1 - 0.0047 17.0 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Alk_phosphatase PF00245.15 KXX75706.1 - 1.4e-62 211.7 0.0 5.2e-62 209.8 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 KXX75706.1 - 5.7e-06 25.8 0.6 2.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX75706.1 - 0.0001 21.6 0.1 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KXX75706.1 - 0.016 13.6 0.2 0.023 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TPR_2 PF07719.12 KXX75707.1 - 7.7e-26 87.9 18.5 0.00026 20.6 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75707.1 - 6.7e-25 86.5 22.3 4.4e-08 32.6 0.1 8.1 5 2 2 7 7 7 5 TPR repeat Apc3 PF12895.2 KXX75707.1 - 4e-24 84.5 18.6 2.7e-18 65.8 0.7 5.6 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KXX75707.1 - 5.2e-23 79.6 12.3 4.8e-05 22.7 1.4 9.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KXX75707.1 - 3.7e-21 75.2 17.5 0.0065 16.7 0.2 8.8 6 3 3 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75707.1 - 2.2e-18 66.4 22.8 7e-06 26.5 0.5 7.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX75707.1 - 2.7e-17 62.4 22.4 1.6e-07 31.1 0.6 8.4 4 3 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75707.1 - 1.9e-16 59.0 26.0 0.019 15.5 0.2 10.6 5 2 6 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75707.1 - 4.4e-14 51.1 0.5 0.003 17.2 0.6 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KXX75707.1 - 3e-06 26.9 19.0 0.11 12.4 0.3 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX75707.1 - 8e-06 25.2 18.7 1.4 8.8 0.2 8.5 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KXX75707.1 - 0.0001 22.5 16.7 0.14 12.7 0.7 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 KXX75707.1 - 0.00017 20.7 8.7 0.15 11.1 0.0 5.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX75707.1 - 0.00039 20.4 1.3 16 5.9 0.0 7.1 8 1 0 8 8 8 0 Tetratricopeptide repeat Cohesin_load PF10345.4 KXX75707.1 - 0.0055 14.9 0.1 0.59 8.2 0.0 2.7 2 1 0 3 3 3 1 Cohesin loading factor TPR_9 PF13371.1 KXX75707.1 - 0.012 15.4 12.8 12 5.8 0.3 5.7 4 1 3 7 7 7 0 Tetratricopeptide repeat ORC2 PF04084.9 KXX75708.1 - 1.1e-83 280.7 0.0 1.8e-53 181.5 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 GMC_oxred_N PF00732.14 KXX75709.1 - 2e-54 184.7 0.0 3.3e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX75709.1 - 5.2e-32 111.1 0.4 1.3e-31 109.8 0.3 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX75709.1 - 2.2e-05 23.5 0.0 0.088 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX75709.1 - 0.00029 19.7 0.0 0.12 11.1 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 KXX75709.1 - 0.0078 16.2 0.0 4.9 7.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX75709.1 - 0.013 15.5 0.1 0.052 13.5 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX75709.1 - 0.025 13.0 0.0 0.75 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KXX75709.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KXX75709.1 - 0.12 12.2 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PGP_phosphatase PF09419.5 KXX75710.1 - 5.8e-68 227.4 0.0 6.7e-68 227.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KXX75710.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like AMP-binding PF00501.23 KXX75711.1 - 9.8e-49 165.8 0.0 1.4e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX75711.1 - 0.0087 16.9 0.0 0.02 15.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_10 PF13374.1 KXX75712.1 - 4.7e-44 147.1 14.2 1.6e-10 40.5 0.1 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KXX75712.1 - 1.2e-43 146.9 19.6 3.2e-18 65.4 0.8 4.8 2 1 2 4 4 4 4 Tetratricopeptide repeat Patatin PF01734.17 KXX75712.1 - 2.5e-25 89.6 0.1 5.4e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.1 KXX75712.1 - 2.9e-16 58.8 6.7 3.3e-07 29.8 0.8 4.3 2 1 2 4 4 4 4 TPR repeat TPR_7 PF13176.1 KXX75712.1 - 8.9e-16 56.3 15.9 0.0002 20.9 0.0 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX75712.1 - 2.9e-15 55.1 17.7 6.2e-05 22.4 0.3 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75712.1 - 4.5e-14 51.1 15.6 0.00042 20.0 0.2 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX75712.1 - 9.7e-11 40.9 3.2 0.42 10.9 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75712.1 - 5.2e-10 38.3 11.9 0.012 15.2 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX75712.1 - 7e-09 36.1 18.5 4.2e-06 27.2 0.5 5.6 4 2 2 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75712.1 - 7.4e-09 35.4 18.6 0.02 15.5 0.1 7.3 5 1 3 8 8 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX75712.1 - 8e-08 31.4 0.0 1.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 KXX75712.1 - 4.5e-05 23.7 7.6 0.078 13.3 1.6 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 KXX75712.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KXX75712.1 - 0.012 15.6 0.4 0.04 13.8 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain TPR_21 PF09976.4 KXX75712.1 - 0.012 15.5 4.8 1.8 8.5 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 KXX75712.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Tcf25 PF04910.9 KXX75712.1 - 0.019 13.9 0.0 3.6 6.4 0.0 2.6 2 1 1 3 3 3 0 Transcriptional repressor TCF25 TPR_4 PF07721.9 KXX75712.1 - 0.023 15.0 10.9 9.5 6.9 0.0 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat Peripla_BP_2 PF01497.13 KXX75712.1 - 0.13 11.3 0.0 0.79 8.8 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein ApoLp-III PF07464.6 KXX75712.1 - 0.17 11.9 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_3 PF07720.7 KXX75712.1 - 0.44 10.3 1.6 31 4.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX75712.1 - 0.97 10.0 20.2 2.9 8.5 0.3 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Proteasome PF00227.21 KXX75713.1 - 1.6e-36 125.3 0.0 2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 KXX75714.1 - 3.7e-47 159.9 0.0 1.5e-45 154.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX75714.1 - 6.1e-29 99.7 0.0 1.2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX75714.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KXX75714.1 - 0.1 10.9 0.0 0.2 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 KXX75714.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CutC PF03932.9 KXX75715.1 - 2e-14 53.3 0.5 4e-05 22.9 0.1 3.9 3 1 0 3 3 3 3 CutC family Myb_DNA-bind_3 PF12776.2 KXX75716.1 - 0.017 15.6 0.8 0.049 14.2 0.3 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cas_Csd1 PF09709.5 KXX75716.1 - 0.06 11.6 0.1 0.08 11.2 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DUF4066 PF13278.1 KXX75717.1 - 8.1e-15 54.4 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX75717.1 - 1.5e-07 30.9 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.20 KXX75719.1 - 2.9e-13 49.5 0.0 5.6e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75719.1 - 0.00013 21.1 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KXX75719.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AA_permease_2 PF13520.1 KXX75720.1 - 2.1e-75 253.8 36.5 2.8e-75 253.4 25.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX75720.1 - 5.6e-20 71.1 27.6 8.1e-20 70.6 19.1 1.3 1 1 0 1 1 1 1 Amino acid permease HET PF06985.6 KXX75721.1 - 1.1e-34 119.5 0.1 2e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VSP PF03302.8 KXX75723.1 - 0.00039 19.1 0.7 0.00057 18.6 0.5 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 KXX75723.1 - 0.0037 16.5 2.8 0.0082 15.4 1.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KXX75723.1 - 0.029 13.9 0.4 0.064 12.8 0.3 1.5 1 0 0 1 1 1 0 Podoplanin CorA PF01544.13 KXX75724.1 - 2.1e-05 23.7 0.2 3.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2510 PF10708.4 KXX75724.1 - 1.7 8.1 6.5 8.9 5.8 4.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2510) Cellulase PF00150.13 KXX75725.1 - 6.5e-39 133.8 0.1 1.9e-36 125.7 0.2 2.0 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) RNase_H PF00075.19 KXX75727.1 - 7.9e-13 48.8 0.0 5.3e-12 46.2 0.0 2.4 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.1 KXX75727.1 - 0.021 14.5 0.1 0.47 10.2 0.1 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like HET PF06985.6 KXX75728.1 - 3.8e-13 49.7 0.0 7.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sdh_cyt PF01127.17 KXX75731.1 - 1.2e-18 67.1 1.7 1.6e-18 66.6 1.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 KXX75732.1 - 6.1e-28 96.7 0.0 1.4e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KXX75732.1 - 3.7e-19 68.4 0.0 9.6e-19 67.1 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KXX75732.1 - 0.045 13.8 0.1 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Complex1_LYR PF05347.10 KXX75734.1 - 4.1e-07 29.7 2.6 6.8e-07 28.9 0.2 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX75734.1 - 0.0042 17.2 6.5 0.063 13.4 4.5 2.2 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L24e PF01246.15 KXX75734.1 - 0.31 10.9 1.6 1.1 9.1 0.8 1.9 1 1 1 2 2 2 0 Ribosomal protein L24e Mito_carr PF00153.22 KXX75735.1 - 4.1e-44 148.2 7.2 3.5e-16 58.6 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein NPR3 PF03666.8 KXX75735.1 - 0.091 11.2 3.6 0.13 10.7 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neuro_bHLH PF12533.3 KXX75735.1 - 1.6 9.5 9.2 3.9 8.3 6.2 1.8 1 1 0 1 1 1 0 Neuronal helix-loop-helix transcription factor AAA PF00004.24 KXX75736.1 - 1.4e-85 284.1 0.0 1.7e-46 157.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX75736.1 - 3.6e-14 52.3 0.0 2.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX75736.1 - 7.3e-12 45.6 0.6 9e-05 22.5 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.9 KXX75736.1 - 2.4e-10 40.2 0.7 6.9e-05 22.6 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX75736.1 - 8.9e-10 38.8 0.5 0.0041 17.2 0.0 3.9 2 2 1 3 3 2 2 AAA domain AAA_33 PF13671.1 KXX75736.1 - 2.9e-09 36.9 0.0 0.0006 19.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KXX75736.1 - 6.4e-09 35.7 0.0 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KXX75736.1 - 8.6e-09 35.5 0.2 0.00019 21.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KXX75736.1 - 3.2e-08 34.3 1.3 0.0078 17.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KXX75736.1 - 1.5e-07 31.0 2.1 0.028 14.1 0.1 3.7 3 1 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 KXX75736.1 - 1.2e-06 28.5 0.4 0.03 14.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KXX75736.1 - 1.6e-06 27.3 0.0 0.0035 16.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 KXX75736.1 - 1.7e-06 28.3 0.1 0.032 14.5 0.0 2.9 2 1 1 3 3 2 2 ABC transporter TIP49 PF06068.8 KXX75736.1 - 1.8e-06 26.9 0.0 0.034 12.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KXX75736.1 - 1.9e-06 27.9 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KXX75736.1 - 3.4e-06 26.6 0.6 0.055 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KXX75736.1 - 9.4e-06 25.9 0.5 0.23 11.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.10 KXX75736.1 - 2.5e-05 23.1 0.0 0.059 12.0 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KXX75736.1 - 3.8e-05 22.7 0.0 0.02 13.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KXX75736.1 - 5.1e-05 22.9 1.5 0.077 12.6 0.2 3.4 4 0 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.21 KXX75736.1 - 5.4e-05 22.7 0.1 0.34 10.3 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 KXX75736.1 - 5.5e-05 22.4 0.5 0.087 11.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KXX75736.1 - 7.9e-05 22.1 8.5 1.2 8.5 0.2 4.5 2 2 2 4 4 4 1 AAA domain NB-ARC PF00931.17 KXX75736.1 - 9.1e-05 21.4 0.2 0.13 11.0 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 KXX75736.1 - 0.00018 21.5 0.2 0.12 12.4 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Vps4_C PF09336.5 KXX75736.1 - 0.00026 20.7 0.0 0.014 15.2 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 KXX75736.1 - 0.00069 18.7 0.0 1.5 7.8 0.0 2.7 3 0 0 3 3 3 2 KaiC AAA_3 PF07726.6 KXX75736.1 - 0.0013 18.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX75736.1 - 0.0018 17.8 0.3 0.58 9.6 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KXX75736.1 - 0.002 17.8 0.1 2.5 7.7 0.0 2.7 2 0 0 2 2 2 1 NTPase Cytidylate_kin2 PF13189.1 KXX75736.1 - 0.0022 17.9 0.0 0.83 9.5 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 KXX75736.1 - 0.0024 17.5 0.1 6.6 6.3 0.0 3.2 3 1 1 4 4 3 0 Archaeal ATPase UPF0079 PF02367.12 KXX75736.1 - 0.0029 17.2 0.9 0.6 9.7 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KXX75736.1 - 0.003 17.0 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 KXX75736.1 - 0.004 16.6 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SKI PF01202.17 KXX75736.1 - 0.0046 16.8 4.4 0.61 9.9 0.0 2.8 3 0 0 3 3 2 2 Shikimate kinase PhoH PF02562.11 KXX75736.1 - 0.0049 16.1 0.7 1.1 8.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.1 KXX75736.1 - 0.005 16.4 0.8 3.6 7.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.13 KXX75736.1 - 0.0076 15.9 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.4 KXX75736.1 - 0.0085 15.5 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KXX75736.1 - 0.019 14.5 0.4 3.9 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 KXX75736.1 - 0.026 14.3 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KXX75736.1 - 0.066 12.0 0.1 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 KXX75736.1 - 0.12 11.2 0.0 9 5.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 KXX75736.1 - 0.15 12.3 6.2 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Hpr_kinase_C PF07475.7 KXX75736.1 - 0.16 11.2 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SRPRB PF09439.5 KXX75736.1 - 0.16 11.1 1.6 12 5.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KXX75736.1 - 0.2 10.8 0.1 0.92 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Pkinase PF00069.20 KXX75737.1 - 1.2e-10 41.0 0.0 2.2e-06 27.0 0.0 2.5 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75737.1 - 3.1e-05 23.1 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase AAA PF00004.24 KXX75738.1 - 1.6e-85 284.0 0.0 1.8e-46 157.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX75738.1 - 4e-14 52.2 0.0 2.6e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX75738.1 - 6.9e-12 45.7 0.5 0.0001 22.3 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.9 KXX75738.1 - 2.5e-10 40.2 0.6 7.2e-05 22.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX75738.1 - 1e-09 38.6 0.6 0.0043 17.1 0.0 3.9 2 2 1 3 3 2 2 AAA domain AAA_33 PF13671.1 KXX75738.1 - 3.3e-09 36.7 0.0 0.00063 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KXX75738.1 - 7e-09 35.6 0.0 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KXX75738.1 - 9e-09 35.4 0.2 0.0002 21.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KXX75738.1 - 2.7e-08 34.6 1.0 0.0082 16.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KXX75738.1 - 1.7e-07 30.8 2.0 0.029 14.0 0.1 3.7 3 1 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 KXX75738.1 - 1.5e-06 28.2 0.5 0.031 14.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KXX75738.1 - 1.5e-06 27.4 0.0 0.0037 16.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 KXX75738.1 - 1.9e-06 28.2 0.1 0.034 14.4 0.0 2.9 2 1 1 3 3 2 2 ABC transporter TIP49 PF06068.8 KXX75738.1 - 1.9e-06 26.8 0.0 0.035 12.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KXX75738.1 - 2.1e-06 27.8 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KXX75738.1 - 3.7e-06 26.4 0.6 0.057 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KXX75738.1 - 1e-05 25.8 0.5 0.24 11.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.10 KXX75738.1 - 2.8e-05 23.0 0.0 0.062 11.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KXX75738.1 - 4.2e-05 22.6 0.0 0.021 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KXX75738.1 - 5.9e-05 22.6 0.0 0.36 10.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 KXX75738.1 - 6e-05 22.2 0.5 0.09 11.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KXX75738.1 - 6.9e-05 22.5 1.8 0.08 12.5 0.2 3.4 4 0 0 4 4 3 1 NACHT domain NB-ARC PF00931.17 KXX75738.1 - 9.9e-05 21.3 0.2 0.14 10.9 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 KXX75738.1 - 0.00011 21.6 8.7 1.2 8.5 0.2 4.5 2 2 1 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 KXX75738.1 - 0.0002 21.3 0.3 0.12 12.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Vps4_C PF09336.5 KXX75738.1 - 0.00021 21.0 0.0 0.015 15.1 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 KXX75738.1 - 0.00076 18.6 0.0 1.6 7.8 0.0 2.7 3 0 0 3 3 3 2 KaiC AAA_3 PF07726.6 KXX75738.1 - 0.0015 18.1 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX75738.1 - 0.0021 17.6 0.3 0.6 9.5 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KXX75738.1 - 0.0022 17.7 0.1 2.6 7.7 0.0 2.7 2 0 0 2 2 2 1 NTPase Cytidylate_kin2 PF13189.1 KXX75738.1 - 0.0024 17.7 0.0 0.87 9.4 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 KXX75738.1 - 0.0027 17.4 0.0 4 7.0 0.0 3.2 3 1 0 3 3 2 0 Archaeal ATPase ATP-synt_ab PF00006.20 KXX75738.1 - 0.0033 16.9 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KXX75738.1 - 0.0035 16.9 1.1 0.63 9.6 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KXX75738.1 - 0.0043 16.5 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.11 KXX75738.1 - 0.0054 15.9 0.7 1.2 8.3 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.1 KXX75738.1 - 0.0054 16.3 0.8 3.8 7.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain SKI PF01202.17 KXX75738.1 - 0.0055 16.5 4.5 0.64 9.8 0.0 2.8 3 0 0 3 3 2 2 Shikimate kinase Bac_DnaA PF00308.13 KXX75738.1 - 0.0084 15.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.4 KXX75738.1 - 0.0091 15.4 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KXX75738.1 - 0.0094 15.5 0.6 4.1 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 KXX75738.1 - 0.027 14.3 0.0 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KXX75738.1 - 0.072 11.9 0.1 4.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 KXX75738.1 - 0.13 11.0 0.0 9.4 5.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Hpr_kinase_C PF07475.7 KXX75738.1 - 0.17 11.2 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SRPRB PF09439.5 KXX75738.1 - 0.18 10.9 1.7 13 4.9 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 KXX75738.1 - 0.19 12.0 7.2 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KXX75738.1 - 0.22 10.7 0.1 0.96 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 But2 PF09792.4 KXX75740.1 - 0.00039 20.2 0.1 0.00087 19.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AAA PF00004.24 KXX75741.1 - 3.8e-20 72.4 0.0 8.1e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX75741.1 - 0.00095 19.3 0.4 0.051 13.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KXX75741.1 - 0.0028 17.9 0.0 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX75741.1 - 0.0057 16.3 0.1 0.02 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX75741.1 - 0.022 14.7 2.9 0.2 11.6 2.0 2.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 KXX75741.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX75741.1 - 0.025 15.4 0.0 0.076 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX75741.1 - 0.032 13.9 0.1 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KXX75741.1 - 0.067 12.5 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KXX75741.1 - 0.95 8.5 2.4 2 7.4 0.2 2.3 2 1 1 3 3 3 0 KaiC Beta-lactamase PF00144.19 KXX75742.1 - 5.9e-45 153.7 0.0 7.5e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KXX75742.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase HET PF06985.6 KXX75743.1 - 4.4e-27 94.9 0.0 7e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_3 PF13302.1 KXX75744.1 - 3e-09 37.1 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX75744.1 - 1.4e-07 31.4 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.11 KXX75744.1 - 0.005 16.4 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Ilarvirus coat protein DIL PF01843.14 KXX75745.1 - 1.7e-20 72.8 1.6 3.2e-18 65.5 1.1 2.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 KXX75745.1 - 1.2e-18 67.2 0.1 3.9e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75745.1 - 7.1e-16 57.1 0.1 2.2e-06 27.1 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 KXX75745.1 - 1e-14 54.5 0.1 1.5e-07 31.7 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX75745.1 - 7.5e-13 48.2 0.1 2.8e-05 24.1 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75745.1 - 1.1e-09 37.5 0.1 0.028 14.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat EcKinase PF02958.15 KXX75746.1 - 8e-21 74.4 0.0 2.3e-12 46.6 0.2 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 KXX75746.1 - 9.4e-09 35.3 2.5 1.6e-08 34.6 1.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KXX75746.1 - 3.8e-08 32.3 0.1 6.1e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Cytochrom_B561 PF03188.11 KXX75747.1 - 6.4e-18 64.8 6.0 1.1e-17 64.1 4.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 KXX75747.1 - 0.0068 16.4 12.8 0.89 9.5 6.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) DUF588 PF04535.7 KXX75747.1 - 0.011 15.3 0.9 0.018 14.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) PepSY_TM_1 PF13172.1 KXX75747.1 - 0.014 15.1 0.1 0.014 15.1 0.1 3.2 3 0 0 3 3 3 0 PepSY-associated TM helix ABC2_membrane_5 PF13346.1 KXX75747.1 - 0.023 13.9 1.6 0.033 13.4 0.2 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2162 PF09930.4 KXX75747.1 - 0.088 11.9 3.4 0.11 11.6 0.9 2.0 1 1 1 2 2 2 0 Predicted transporter (DUF2162) Allantoicase PF03561.10 KXX75748.1 - 1e-107 356.2 0.1 4.3e-58 195.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Sugar_tr PF00083.19 KXX75749.1 - 8.6e-100 334.4 16.8 1.2e-99 333.9 11.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75749.1 - 2.5e-28 98.7 16.8 2.5e-28 98.7 11.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX75749.1 - 4.4e-07 28.6 22.9 0.0002 19.8 4.0 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KXX75749.1 - 0.0049 15.5 1.2 0.0077 14.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KXX75749.1 - 0.48 8.4 5.0 2.6 6.0 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 KXX75750.1 - 4.9e-106 353.9 0.7 5.7e-106 353.7 0.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4149 PF13664.1 KXX75750.1 - 1 9.4 20.0 2.6 8.1 0.2 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) AMP-binding PF00501.23 KXX75751.1 - 3.7e-71 239.6 0.0 4.4e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX75751.1 - 5.9e-13 49.5 0.0 1.6e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lipase_GDSL PF00657.17 KXX75752.1 - 2.7e-15 56.8 0.1 4e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KXX75752.1 - 5.7e-13 49.3 0.4 8.2e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KXX75752.1 - 4.9e-07 29.6 0.0 9.6e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family NMT1 PF09084.6 KXX75753.1 - 1.5e-76 256.7 0.0 2.1e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KXX75753.1 - 1.3e-07 31.3 0.1 0.039 13.3 0.0 3.4 2 1 2 4 4 4 3 NMT1-like family Abhydrolase_6 PF12697.2 KXX75754.1 - 2.1e-23 83.4 0.0 2.6e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX75754.1 - 1.8e-15 57.1 0.0 4.6e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX75754.1 - 1.1e-09 38.2 0.0 5.1e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KXX75754.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KXX75754.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Myb_DNA-bind_3 PF12776.2 KXX75755.1 - 1.5e-06 28.6 0.4 1.1e-05 25.9 0.0 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain TraI PF07057.6 KXX75755.1 - 0.041 13.8 0.2 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 DNA helicase TraI Sugar_tr PF00083.19 KXX75756.1 - 1e-96 324.2 14.0 1.2e-96 324.0 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75756.1 - 1.4e-27 96.3 26.3 1.2e-20 73.5 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 KXX75757.1 - 2.1e-38 131.8 0.0 3.6e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus PLA2_B PF01735.13 KXX75758.1 - 2.5e-141 471.2 2.9 3.6e-128 427.8 0.0 2.0 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Clr5 PF14420.1 KXX75760.1 - 7.4e-10 38.5 0.2 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain Ppx-GppA PF02541.11 KXX75761.1 - 2.5e-05 23.6 0.0 4.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Glyco_hydro_76 PF03663.9 KXX75764.1 - 2.1e-118 395.9 3.9 2.9e-118 395.4 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KXX75764.1 - 0.11 11.5 0.2 0.11 11.5 0.1 2.8 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 NACHT PF05729.7 KXX75765.1 - 0.033 13.8 0.1 0.077 12.6 0.1 1.6 1 1 0 1 1 1 0 NACHT domain DUF641 PF04859.7 KXX75767.1 - 0.093 12.4 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 KXX75767.1 - 0.51 10.7 5.6 14 6.1 2.3 2.6 1 1 1 2 2 2 0 SlyX DivIC PF04977.10 KXX75767.1 - 0.6 9.6 2.7 1.8 8.0 1.6 1.9 1 1 1 2 2 2 0 Septum formation initiator Con-6 PF10346.4 KXX75768.1 - 8.8e-33 111.4 5.8 4.5e-18 64.3 0.5 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF4230 PF14014.1 KXX75768.1 - 0.032 14.0 0.9 3.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) SpoIIIAH PF12685.2 KXX75768.1 - 0.042 13.3 3.4 0.47 9.9 2.4 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein Cyclin PF08613.6 KXX75769.1 - 2.4e-36 125.3 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KXX75769.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pex14_N PF04695.8 KXX75769.1 - 0.97 9.4 4.5 2.3 8.2 1.6 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region adh_short PF00106.20 KXX75770.1 - 7.5e-13 48.7 0.0 3.6e-12 46.5 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX75770.1 - 5.7e-05 23.0 0.0 7.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX75770.1 - 0.00031 20.2 0.2 0.014 14.7 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KXX75770.1 - 0.00063 19.4 0.0 0.0024 17.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Ank_2 PF12796.2 KXX75771.1 - 9.7e-28 96.3 0.0 1.2e-08 35.1 0.1 5.7 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Pkinase PF00069.20 KXX75771.1 - 7.1e-22 77.8 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75771.1 - 1.3e-16 60.4 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.1 KXX75771.1 - 9.3e-16 57.4 7.5 0.0005 20.2 0.3 6.9 5 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75771.1 - 1.2e-14 52.9 1.7 0.0011 18.9 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.25 KXX75771.1 - 5.2e-13 48.0 18.9 0.0075 16.0 0.0 9.1 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 KXX75771.1 - 5.4e-13 49.0 1.4 1.6e-06 28.4 0.2 5.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Sel1 PF08238.7 KXX75771.1 - 0.0016 19.0 0.1 0.0065 17.0 0.1 2.1 1 0 0 1 1 1 1 Sel1 repeat Kdo PF06293.9 KXX75771.1 - 0.072 12.1 0.0 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHZ PF09649.5 KXX75772.1 - 0.00016 20.7 0.9 0.00031 19.8 0.6 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ Peptidase_M24 PF00557.19 KXX75773.1 - 1.3e-53 181.6 0.2 1.8e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KXX75773.1 - 1.8e-28 98.5 0.0 3.7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribonuclease_3 PF00636.21 KXX75776.1 - 1.6e-25 89.7 0.0 2.8e-13 50.3 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX75776.1 - 3.1e-20 72.4 0.1 7e-08 32.4 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 KXX75776.1 - 7.2e-17 61.0 0.4 1.7e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX75776.1 - 7.7e-17 61.2 0.0 1.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KXX75776.1 - 2.2e-10 40.6 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 KXX75776.1 - 3.7e-07 29.8 0.0 1.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 KXX75776.1 - 0.00015 20.7 0.1 0.00024 20.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KXX75776.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 SecA DEAD-like domain Glyco_hydro_62 PF03664.8 KXX75777.1 - 2.2e-79 266.3 1.6 2.7e-79 266.1 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_43 PF04616.9 KXX75778.1 - 1.9e-64 217.5 5.4 2.3e-64 217.2 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.8 KXX75778.1 - 1.5e-13 50.6 0.3 1.8e-07 30.9 0.0 3.2 1 1 2 3 3 3 2 Alpha-L-arabinofuranosidase B (ABFB) TPP_enzyme_N PF02776.13 KXX75779.1 - 5.2e-40 136.7 0.1 9.1e-39 132.6 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KXX75779.1 - 1.2e-20 73.5 0.0 2.9e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KXX75779.1 - 4.7e-20 71.7 0.0 2.9e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Nbs1_C PF08599.5 KXX75779.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 DUF1996 PF09362.5 KXX75780.1 - 3.9e-86 288.5 0.1 4.7e-86 288.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_16 PF13191.1 KXX75781.1 - 5.7e-05 23.1 0.0 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX75781.1 - 0.0002 21.4 0.0 0.00064 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX75781.1 - 0.00056 19.5 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.22 KXX75781.1 - 0.0034 17.6 0.0 0.0097 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 KXX75781.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KXX75781.1 - 0.012 16.4 1.5 0.069 13.9 0.4 2.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KXX75781.1 - 0.022 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 KXX75781.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KXX75781.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX75781.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KXX75781.1 - 0.092 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KXX75781.1 - 0.099 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 KXX75781.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase IncA PF04156.9 KXX75782.1 - 0.19 11.3 3.7 0.34 10.4 2.3 1.5 1 1 0 1 1 1 0 IncA protein HisKA PF00512.20 KXX75782.1 - 0.23 11.4 4.3 0.14 12.1 1.6 1.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain KfrA_N PF11740.3 KXX75782.1 - 5.9 7.3 10.5 14 6.1 0.2 2.4 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term VanY PF02557.12 KXX75784.1 - 0.08 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HeLo PF14479.1 KXX75785.1 - 7e-28 97.8 2.6 1.9e-27 96.3 1.8 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 KXX75785.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF1627 PF07789.7 KXX75785.1 - 0.027 14.0 0.1 0.052 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Fungal_trans_2 PF11951.3 KXX75786.1 - 2.3e-43 148.2 2.5 7.8e-43 146.5 1.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Paf67 PF10255.4 KXX75787.1 - 7.3e-151 502.6 0.2 8.5e-151 502.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KXX75787.1 - 0.012 15.4 0.2 0.11 12.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HBS1_N PF08938.5 KXX75787.1 - 0.025 14.7 3.3 0.053 13.6 2.3 1.5 1 0 0 1 1 1 0 HBS1 N-terminus GTP_EFTU PF00009.22 KXX75788.1 - 9.4e-52 175.1 0.0 1.7e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KXX75788.1 - 6.9e-16 57.8 0.0 1.6e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX75788.1 - 4.1e-10 39.6 0.0 1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KXX75788.1 - 5.1e-09 35.7 0.0 2.4e-06 27.1 0.0 3.3 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.1 KXX75788.1 - 1.7e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX75788.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RRM_6 PF14259.1 KXX75789.1 - 1.5e-11 44.1 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX75789.1 - 4.6e-10 38.9 0.0 8.9e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75789.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G0-G1_switch_2 PF15103.1 KXX75789.1 - 0.075 13.2 1.8 0.17 12.1 1.3 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Asp-B-Hydro_N PF05279.6 KXX75789.1 - 0.23 11.2 10.7 0.36 10.6 7.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 KXX75789.1 - 1.1 6.9 1.6 1.3 6.6 1.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF3384 PF11864.3 KXX75791.1 - 0.051 12.0 0.0 0.051 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) FAD_binding_4 PF01565.18 KXX75792.1 - 6.7e-16 58.0 1.5 1.3e-15 57.0 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75792.1 - 2.2e-10 40.2 0.6 4.1e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX75792.1 - 0.064 12.3 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Usp PF00582.21 KXX75794.1 - 3.5e-13 49.9 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family Ribosomal_L32e PF01655.13 KXX75795.1 - 3.1e-50 168.8 2.4 4.3e-50 168.3 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Glyco_transf_15 PF01793.11 KXX75795.1 - 0.14 11.0 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DnaJ PF00226.26 KXX75796.1 - 9.9e-24 82.8 2.5 2.5e-23 81.5 1.7 1.8 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 KXX75796.1 - 3e-19 68.7 0.0 6.6e-17 61.1 0.0 2.7 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KXX75796.1 - 7.4e-13 48.3 17.4 1.1e-12 47.7 12.0 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KXX75796.1 - 0.017 14.8 7.0 0.32 10.6 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UreE_N PF02814.10 KXX75796.1 - 0.049 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain zf-CHY PF05495.7 KXX75796.1 - 0.57 10.3 7.5 0.65 10.1 0.4 2.3 2 0 0 2 2 2 0 CHY zinc finger DUF1356 PF07092.7 KXX75796.1 - 2.3 7.3 4.5 9.5 5.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Stc1 PF12898.2 KXX75796.1 - 5.2 7.1 13.4 7.2 6.7 1.8 2.3 1 1 1 2 2 2 0 Stc1 domain Aminotran_5 PF00266.14 KXX75797.1 - 5.3e-13 48.4 0.0 1.4e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KXX75797.1 - 1.4e-05 24.3 0.2 2.5e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KXX75797.1 - 0.00014 20.3 0.0 0.0002 19.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_1c PF00749.16 KXX75798.1 - 4.2e-93 311.4 0.0 5.6e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Fmp27 PF10344.4 KXX75799.1 - 5.4e-249 828.4 0.0 7.4e-249 827.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KXX75799.1 - 2.8e-175 583.5 2.9 1.3e-174 581.3 0.1 2.8 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KXX75799.1 - 8.2e-156 519.1 0.0 2e-155 517.8 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KXX75799.1 - 8.4e-55 184.9 0.0 1.9e-54 183.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KXX75799.1 - 1.9e-53 180.4 0.1 4.9e-53 179.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KXX75799.1 - 1.1e-33 115.7 0.1 3.5e-33 114.1 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.16 KXX75799.1 - 1.8e-24 85.6 0.0 4.5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KXX75799.1 - 5.3e-06 25.9 0.1 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain HET PF06985.6 KXX75800.1 - 1.1e-26 93.6 1.4 9.5e-26 90.6 0.8 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.9 KXX75801.1 - 5.8e-43 147.0 3.8 6.6e-43 146.8 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.20 KXX75802.1 - 7.5e-19 68.2 4.2 1.2e-18 67.5 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX75802.1 - 4.6e-11 42.7 0.8 7.4e-11 42.0 0.6 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX75802.1 - 0.013 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KXX75802.1 - 0.022 14.2 0.5 0.062 12.7 0.4 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KXX75802.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ILVD_EDD PF00920.16 KXX75803.1 - 3.4e-153 510.7 0.2 3.9e-153 510.6 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Hemerythrin PF01814.18 KXX75804.1 - 2.8e-09 37.2 1.6 5.7e-09 36.2 0.6 1.8 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain DUF3014 PF11219.3 KXX75804.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) Glyco_hydro_10 PF00331.15 KXX75805.1 - 1.1e-95 320.3 0.1 1.3e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.19 KXX75805.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel WI12 PF07107.6 KXX75805.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 Wound-induced protein WI12 Glyco_hydro_43 PF04616.9 KXX75807.1 - 7.5e-35 120.3 0.6 9e-35 120.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nucleos_tra2_C PF07662.8 KXX75808.1 - 1.3e-66 224.0 0.4 1.3e-66 224.0 0.2 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KXX75808.1 - 8.3e-21 74.1 2.6 8.3e-21 74.1 1.8 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Sugar_tr PF00083.19 KXX75809.1 - 1.5e-102 343.5 19.8 1.8e-102 343.2 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75809.1 - 6.2e-27 94.2 29.6 1.5e-24 86.3 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PNK3P PF08645.6 KXX75810.1 - 1.3e-55 187.2 0.0 1.9e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KXX75810.1 - 3.2e-31 108.1 0.0 1.7e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KXX75810.1 - 0.0011 18.1 0.0 0.016 14.3 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin APS_kinase PF01583.15 KXX75810.1 - 0.0092 15.6 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 KXX75810.1 - 0.024 15.4 0.0 0.054 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX75810.1 - 0.024 14.1 0.0 0.081 12.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX75810.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KXX75810.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX75810.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 KXX75810.1 - 0.2 10.8 0.0 8.3 5.5 0.0 2.3 1 1 0 2 2 2 0 Chromatin associated protein KTI12 HET PF06985.6 KXX75811.1 - 9.9e-35 119.7 0.0 2e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BBE PF08031.7 KXX75812.1 - 1.8e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KXX75813.1 - 8.3e-17 60.9 0.8 1.8e-16 59.8 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75813.1 - 5.7e-13 48.5 0.1 1.5e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX75813.1 - 0.064 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GMC_oxred_N PF00732.14 KXX75814.1 - 2.1e-59 201.0 0.0 2.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX75814.1 - 5.1e-32 111.1 0.1 9.1e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX75814.1 - 1.1e-08 34.3 0.2 1.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KXX75814.1 - 7.8e-06 25.8 0.4 2.9e-05 24.0 0.1 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX75814.1 - 0.00016 20.6 0.7 0.013 14.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX75814.1 - 0.00028 19.9 0.1 0.00041 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KXX75814.1 - 0.016 15.2 0.3 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX75814.1 - 0.037 12.4 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KXX75814.1 - 0.058 12.4 0.1 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KXX75814.1 - 0.25 10.2 0.0 1.4 7.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NTF2 PF02136.15 KXX75815.1 - 2.7e-29 101.9 0.0 3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 KXX75816.1 - 2.6e-40 136.9 17.1 3.1e-40 136.6 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Seipin PF06775.9 KXX75817.1 - 4.2e-48 163.5 0.0 5.5e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF3210 PF11489.3 KXX75819.1 - 2.9e-225 750.2 81.8 2.9e-225 750.2 56.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Nup96 PF12110.3 KXX75820.1 - 1e-61 208.6 0.0 1.6e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KXX75820.1 - 4.7e-44 149.6 0.0 7.5e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KXX75820.1 - 2.9e-06 27.4 299.4 1.8e-05 24.9 21.8 9.3 3 2 4 7 7 7 4 Nucleoporin FG repeat region p450 PF00067.17 KXX75821.1 - 2.4e-29 102.1 0.0 5.3e-27 94.4 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Potass_KdpF PF09604.5 KXX75821.1 - 0.25 11.2 3.2 0.56 10.1 2.2 1.6 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Gryzun PF07919.7 KXX75822.1 - 4.2e-107 358.7 0.1 5.5e-107 358.3 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KXX75822.1 - 1.1e-77 260.9 2.1 8.2e-75 251.4 1.7 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KXX75822.1 - 0.0018 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Ran-binding PF05508.6 KXX75823.1 - 1.4e-105 352.5 0.0 1.7e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CDC45 PF02724.9 KXX75823.1 - 2.7 5.8 6.3 2.1 6.3 0.2 2.6 3 0 0 3 3 3 0 CDC45-like protein Dna2 PF08696.6 KXX75824.1 - 8.2e-73 244.1 0.1 2.7e-72 242.4 0.0 1.8 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 KXX75824.1 - 4e-52 176.4 0.0 8.7e-52 175.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KXX75824.1 - 3.9e-38 131.3 0.1 1.6e-19 70.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KXX75824.1 - 5.2e-13 49.0 0.0 4.4e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.12 KXX75824.1 - 4.5e-10 39.6 0.2 8.3e-09 35.5 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_19 PF13245.1 KXX75824.1 - 3.7e-09 36.2 0.2 3.7e-09 36.2 0.1 2.2 2 0 0 2 2 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KXX75824.1 - 5.7e-09 35.7 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KXX75824.1 - 0.00012 21.6 0.1 0.63 9.5 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KXX75824.1 - 0.00088 18.6 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KXX75824.1 - 0.0022 17.6 0.0 0.006 16.2 0.0 1.7 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 KXX75824.1 - 0.0063 15.9 0.1 0.038 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX75824.1 - 0.012 15.5 0.1 0.063 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KXX75824.1 - 0.014 15.0 0.1 0.041 13.5 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KXX75824.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RuvB_N PF05496.7 KXX75824.1 - 0.025 13.6 0.1 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KXX75824.1 - 0.033 14.3 0.3 0.78 9.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.15 KXX75824.1 - 0.067 11.6 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF2075 PF09848.4 KXX75824.1 - 0.093 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 KXX75824.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.9 KXX75824.1 - 0.13 11.1 0.1 0.77 8.6 0.1 2.0 1 1 0 1 1 1 0 PIF1-like helicase DUF87 PF01935.12 KXX75824.1 - 0.21 11.3 0.2 0.46 10.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 adh_short PF00106.20 KXX75825.1 - 9.3e-15 54.9 7.1 1.6e-13 50.9 5.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX75825.1 - 6.9e-14 52.2 0.4 4.6e-13 49.4 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX75825.1 - 3.6e-05 23.4 1.8 7.9e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 KR domain GTP_EFTU PF00009.22 KXX75826.1 - 2.4e-44 151.0 0.1 4e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KXX75826.1 - 4.4e-14 52.4 0.1 1.5e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KXX75826.1 - 3.8e-06 26.9 0.2 9e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KXX75826.1 - 2.6e-05 24.1 0.0 8.8e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase UCH_1 PF13423.1 KXX75827.1 - 1.6e-56 191.9 0.0 2.4e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KXX75827.1 - 2.1e-27 96.4 0.0 5.2e-27 95.1 0.0 1.8 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 KXX75827.1 - 4.7e-09 35.7 0.0 3.7e-07 29.5 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KXX75827.1 - 0.081 12.8 0.3 14 5.7 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Mito_carr PF00153.22 KXX75828.1 - 3.6e-55 183.6 5.2 2.9e-20 71.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.15 KXX75828.1 - 0.026 14.1 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Glyco_hydro_17 PF00332.13 KXX75829.1 - 2.5e-08 33.3 0.2 8.9e-06 24.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 TPR_12 PF13424.1 KXX75831.1 - 1.7e-08 34.2 13.3 0.012 15.5 1.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX75831.1 - 2.3e-08 33.3 10.1 0.2 11.6 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX75831.1 - 1e-05 24.8 4.6 9.2 6.0 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KXX75831.1 - 2.2e-05 24.0 8.9 0.047 13.3 0.7 3.8 2 2 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 KXX75831.1 - 0.00034 21.2 8.5 0.078 13.6 0.1 4.7 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX75831.1 - 0.00064 19.3 3.6 1.1 9.2 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Ank_4 PF13637.1 KXX75831.1 - 0.0007 20.0 0.0 0.0025 18.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX75831.1 - 0.00091 19.5 0.0 0.003 17.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) HET PF06985.6 KXX75831.1 - 0.0023 18.0 0.8 0.0097 16.0 0.0 2.3 2 1 1 3 3 2 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 KXX75831.1 - 0.018 15.2 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 KXX75831.1 - 0.091 12.6 0.0 15 5.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TPR_17 PF13431.1 KXX75831.1 - 0.11 12.7 2.4 37 4.8 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX75831.1 - 0.12 12.1 4.8 1 9.3 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX75831.1 - 0.25 11.6 6.3 1.8 8.9 0.9 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX75831.1 - 0.56 10.7 11.5 4.6 7.9 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX75831.1 - 0.66 10.7 20.8 5.3 7.9 0.3 6.8 7 1 1 8 8 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KXX75831.1 - 1.5 8.8 12.3 0.69 9.9 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX75831.1 - 2.9 8.5 13.0 19 5.9 0.3 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.9 KXX75832.1 - 1.4e-16 60.9 0.0 2.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX75832.1 - 1.5e-12 46.9 15.4 4.5e-12 45.3 10.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Ank_2 PF12796.2 KXX75833.1 - 4.4e-12 46.1 0.3 2e-11 44.0 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX75833.1 - 7.5e-10 38.7 0.0 1.4e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX75833.1 - 9.8e-09 34.6 0.0 0.00023 20.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KXX75833.1 - 3.4e-08 33.7 0.0 0.0042 17.5 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75833.1 - 1.5e-07 30.9 0.0 0.00068 19.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Dppa2_A PF14049.1 KXX75833.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates FAD_binding_3 PF01494.14 KXX75834.1 - 4.1e-16 58.9 0.2 1.2e-14 54.1 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KXX75834.1 - 7.5e-06 25.0 0.4 1.2e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KXX75834.1 - 1.4e-05 23.9 0.0 0.0073 14.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KXX75834.1 - 1.8e-05 23.8 0.8 0.011 14.6 0.6 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX75834.1 - 7.6e-05 22.6 0.4 0.00033 20.6 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX75834.1 - 0.00014 21.8 0.2 0.00031 20.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX75834.1 - 0.00014 20.8 0.4 0.00019 20.4 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KXX75834.1 - 0.00033 19.2 0.0 0.12 10.8 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 KXX75834.1 - 0.00069 19.9 0.0 0.023 15.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KXX75834.1 - 0.003 16.7 0.3 0.038 13.0 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX75834.1 - 0.0073 16.3 0.1 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KXX75834.1 - 0.038 13.8 1.7 0.49 10.2 0.4 2.5 2 0 0 2 2 2 0 ThiF family DUF3907 PF13047.1 KXX75834.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) FAD_binding_4 PF01565.18 KXX75835.1 - 1.9e-31 108.3 0.0 3.4e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KXX75835.1 - 5.7e-20 71.6 0.0 7.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain zf-C2H2_jaz PF12171.3 KXX75836.1 - 0.0019 18.2 6.7 0.29 11.3 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KXX75836.1 - 0.0096 16.1 4.7 0.0096 16.1 3.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KXX75836.1 - 0.016 15.4 0.5 0.016 15.4 0.3 5.3 4 1 1 5 5 5 0 Zinc finger, C2H2 type zf-met PF12874.2 KXX75836.1 - 0.072 13.3 0.8 5.7 7.2 0.0 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 KXX75836.1 - 0.51 10.2 17.8 0.26 11.2 7.3 2.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KXX75836.1 - 2.6 8.5 29.2 0.15 12.4 0.8 5.4 5 1 0 5 5 5 0 C2H2-type zinc finger B12D PF06522.6 KXX75837.1 - 0.19 11.4 7.5 0.27 10.9 0.2 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit HIG_1_N PF04588.8 KXX75837.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.9 3 0 0 3 3 3 0 Hypoxia induced protein conserved region p450 PF00067.17 KXX75838.1 - 1.3e-25 89.8 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.17 KXX75839.1 - 2.1e-11 43.4 0.0 6.1e-11 41.9 0.0 1.7 1 1 1 2 2 2 1 Cupin Cupin_2 PF07883.6 KXX75839.1 - 4.8e-05 22.7 0.0 0.00018 20.9 0.0 1.8 1 1 0 1 1 1 1 Cupin domain Glyco_hydro_2_N PF02837.13 KXX75840.1 - 5.7e-28 97.5 0.0 1.5e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KXX75840.1 - 6e-15 54.9 0.7 1.2e-14 53.8 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KXX75840.1 - 1.9e-11 44.3 0.0 4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 VWA_3 PF13768.1 KXX75841.1 - 7.9e-24 84.1 0.0 1.8e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KXX75841.1 - 5.8e-20 71.1 0.0 1.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 KXX75841.1 - 7.2e-09 34.9 0.0 2.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KXX75841.1 - 4.5e-08 33.3 0.0 9.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain CorA PF01544.13 KXX75842.1 - 4.8e-13 48.7 0.0 3.6e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acyl-CoA_dh_1 PF00441.19 KXX75843.1 - 2.3e-33 115.4 2.0 2.3e-33 115.4 1.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX75843.1 - 1.4e-18 67.4 0.1 3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX75843.1 - 2.1e-15 57.1 4.5 2.2e-15 57.0 1.3 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX75843.1 - 6.5e-15 54.3 0.0 1.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain TPP1 PF10341.4 KXX75843.1 - 0.05 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD DpnD-PcfM PF14207.1 KXX75845.1 - 0.27 11.0 1.0 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 DpnD/PcfM-like protein tRNA_bind PF01588.15 KXX75846.1 - 3.8e-23 81.1 0.1 3.8e-22 77.9 0.1 2.3 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KXX75846.1 - 3.5e-06 27.4 0.0 8.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX75846.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX75846.1 - 0.32 11.0 1.6 0.61 10.1 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.18 KXX75847.1 - 4.4e-71 239.1 0.2 8.3e-71 238.2 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX75847.1 - 1.4e-16 60.1 0.1 5.8e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX75847.1 - 5.5e-05 23.0 0.1 0.00039 20.2 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sld5 PF05916.6 KXX75848.1 - 3.7e-25 88.2 0.0 6.2e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_61 PF03443.9 KXX75849.1 - 5e-58 196.4 0.1 5.7e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_3 PF07859.8 KXX75850.1 - 1.3e-19 70.6 0.4 1.2e-18 67.4 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX75850.1 - 8.6e-10 38.5 0.1 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX75850.1 - 9.5e-08 32.1 2.2 1.3e-07 31.7 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KXX75850.1 - 6.5e-06 25.1 0.0 0.0003 19.6 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 KXX75850.1 - 8e-06 24.9 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 KXX75850.1 - 0.00034 19.2 0.0 0.18 10.3 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KXX75850.1 - 0.00077 18.7 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KXX75850.1 - 0.0012 17.6 0.0 0.0016 17.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DUF2424 PF10340.4 KXX75850.1 - 0.0012 17.5 0.0 0.0062 15.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DLH PF01738.13 KXX75850.1 - 0.066 12.4 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ank_2 PF12796.2 KXX75851.1 - 6.2e-43 145.0 4.4 4e-14 52.7 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX75851.1 - 6.3e-29 99.8 4.0 2.5e-06 27.8 0.2 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KXX75851.1 - 4.5e-28 95.6 2.2 0.00026 20.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KXX75851.1 - 2.9e-27 94.0 2.0 1.8e-08 34.3 0.0 5.9 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75851.1 - 6.1e-19 66.2 0.7 0.018 15.2 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Zn_clus PF00172.13 KXX75851.1 - 1 9.3 15.1 1.9 8.4 10.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KXX75852.1 - 7.6e-39 133.2 0.0 8.7e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2_4 PF13894.1 KXX75854.1 - 0.00011 22.3 9.4 0.011 16.0 2.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX75854.1 - 0.00019 21.5 11.0 0.00066 19.8 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 KXX75854.1 - 0.0016 18.5 1.9 1.7 8.8 0.1 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KXX75854.1 - 0.011 15.8 2.8 0.44 10.8 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KXX75854.1 - 0.023 14.7 5.3 1.9 8.6 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KXX75854.1 - 0.094 12.4 0.7 0.094 12.4 0.5 2.4 2 0 0 2 2 2 0 BED zinc finger Pribosyltran_N PF13793.1 KXX75855.1 - 1.3e-42 144.1 0.8 1.1e-41 141.1 0.1 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KXX75855.1 - 1.7e-40 138.7 2.6 6e-36 123.9 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KXX75855.1 - 1.6e-12 47.2 0.2 5.5e-12 45.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KXX75855.1 - 0.0021 17.2 0.4 0.0041 16.3 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase NTP_transf_3 PF12804.2 KXX75855.1 - 0.032 14.3 0.1 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF218 PF02698.12 KXX75855.1 - 0.052 13.0 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain AF2331-like PF14556.1 KXX75855.1 - 0.092 13.0 0.5 7.6 6.9 0.0 2.9 3 0 0 3 3 3 0 AF2331-like UPF0121 PF03661.8 KXX75856.1 - 5.8e-09 35.4 0.1 9.8e-09 34.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.15 KXX75856.1 - 1.6e-08 34.2 0.0 3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KXX75856.1 - 0.0093 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KXX75856.1 - 0.032 14.4 0.2 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Elong-fact-P_C PF09285.6 KXX75856.1 - 0.063 12.6 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P, C-terminal Rhodanese PF00581.15 KXX75857.1 - 3.1e-13 50.0 0.0 5e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain DUF4448 PF14610.1 KXX75858.1 - 5.7e-20 71.5 0.1 2e-18 66.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KXX75858.1 - 0.0049 17.3 0.9 0.014 15.8 0.7 1.7 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3377 PF11857.3 KXX75858.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) AAA_12 PF13087.1 KXX75859.1 - 7.8e-39 133.1 0.0 1.4e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KXX75859.1 - 7.7e-25 87.8 0.1 3.4e-24 85.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX75859.1 - 2.9e-09 36.5 0.0 1.3e-08 34.4 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KXX75859.1 - 0.00016 20.7 0.1 0.47 9.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KXX75859.1 - 0.00044 20.2 1.6 0.0014 18.6 0.2 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KXX75859.1 - 0.00051 19.6 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KXX75859.1 - 0.0024 17.9 0.0 0.0081 16.2 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KXX75859.1 - 0.0091 16.1 0.1 0.074 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KXX75859.1 - 0.053 12.4 0.1 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Fer4_20 PF14691.1 KXX75859.1 - 0.13 11.9 11.7 0.45 10.1 8.1 1.9 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster ResIII PF04851.10 KXX75859.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Acetyltransf_1 PF00583.19 KXX75861.1 - 2.7e-10 40.1 0.1 4.7e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX75861.1 - 1.1e-08 35.0 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX75861.1 - 2e-06 27.9 0.0 2.4e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX75861.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX75861.1 - 0.0024 17.6 0.0 0.0053 16.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KXX75861.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF2686 PF10887.3 KXX75861.1 - 0.047 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) ABC_membrane PF00664.18 KXX75862.1 - 1.3e-68 231.3 29.2 8.7e-37 127.0 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KXX75862.1 - 7.9e-67 223.7 0.0 1.1e-32 113.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KXX75862.1 - 7.2e-13 48.2 0.5 0.0016 17.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KXX75862.1 - 3.3e-10 40.4 0.1 0.052 13.5 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KXX75862.1 - 1.3e-08 34.1 1.2 0.0032 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX75862.1 - 3.1e-08 33.8 5.0 0.0016 18.4 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KXX75862.1 - 1.5e-07 32.2 0.1 0.006 17.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX75862.1 - 4.4e-06 26.8 1.6 0.15 12.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KXX75862.1 - 4.7e-06 26.3 0.2 0.0044 16.7 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_25 PF13481.1 KXX75862.1 - 4.7e-06 26.1 1.0 0.15 11.4 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 KXX75862.1 - 1.8e-05 24.4 2.5 0.019 14.5 0.1 4.3 4 1 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KXX75862.1 - 1.8e-05 23.9 0.3 0.15 11.1 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_23 PF13476.1 KXX75862.1 - 2e-05 25.0 0.2 0.054 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX75862.1 - 2.6e-05 23.4 0.3 0.088 11.9 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KXX75862.1 - 3e-05 22.8 3.7 0.038 12.5 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_10 PF12846.2 KXX75862.1 - 3.1e-05 23.5 0.4 0.19 11.1 0.0 3.6 3 0 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 KXX75862.1 - 0.00016 21.5 0.1 0.33 10.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 KXX75862.1 - 0.00018 21.3 0.6 1.5 8.8 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KXX75862.1 - 0.0003 21.1 0.4 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KXX75862.1 - 0.00031 20.6 0.8 0.009 15.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA PF00004.24 KXX75862.1 - 0.0016 18.6 0.1 18 5.5 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KXX75862.1 - 0.0028 17.5 0.0 0.53 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX75862.1 - 0.003 17.2 0.2 6.3 6.5 0.1 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KXX75862.1 - 0.0055 15.6 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain MMR_HSR1 PF01926.18 KXX75862.1 - 0.016 15.1 0.5 12 5.9 0.0 3.2 4 0 0 4 4 3 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KXX75862.1 - 0.033 13.6 1.2 0.2 11.1 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KXX75862.1 - 0.064 12.7 2.7 5.3 6.4 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KXX75862.1 - 0.072 12.7 2.3 8.7 6.0 0.0 3.2 4 0 0 4 4 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KXX75862.1 - 0.22 11.7 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 KXX75862.1 - 0.39 9.3 0.0 14 4.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit PRKCSH PF07915.8 KXX75863.1 - 6.3e-19 68.5 0.0 1.6e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein p450 PF00067.17 KXX75865.1 - 4.7e-66 223.2 0.0 5.8e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pox_polyA_pol_C PF12629.2 KXX75865.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain HET PF06985.6 KXX75866.1 - 0.00034 20.7 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KXX75867.1 - 1.8e-24 86.4 0.8 3.1e-24 85.7 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 KXX75868.1 - 1.2e-79 267.6 0.3 3.1e-78 263.0 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KXX75868.1 - 2e-62 210.7 0.0 1.2e-38 132.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KXX75868.1 - 1.2e-22 79.9 0.0 2.9e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HTH_psq PF05225.11 KXX75869.1 - 2.3e-05 23.8 0.0 4e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KXX75869.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Myb_DNA-binding PF00249.26 KXX75869.1 - 0.002 18.1 0.1 0.0069 16.4 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_23 PF13384.1 KXX75869.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.10 KXX75869.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.15 KXX75869.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Transposase CENP-B_N PF04218.8 KXX75869.1 - 0.047 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain ketoacyl-synt PF00109.21 KXX75870.1 - 1.5e-56 191.7 0.6 2e-43 148.7 0.1 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX75870.1 - 4.7e-56 189.3 1.9 2.9e-29 102.0 0.0 3.0 1 1 1 2 2 2 2 KR domain PS-DH PF14765.1 KXX75870.1 - 7.3e-48 163.2 0.1 2.3e-47 161.6 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX75870.1 - 6.1e-40 136.8 6.2 1e-19 71.0 0.0 3.3 2 1 1 3 3 3 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 KXX75870.1 - 3.7e-39 134.9 0.3 9.8e-39 133.5 0.2 1.7 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KXX75870.1 - 2.4e-37 127.3 0.3 9.2e-37 125.5 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX75870.1 - 1.7e-10 40.5 1.4 5.1e-10 39.0 0.9 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX75870.1 - 5.4e-07 29.7 0.0 1.3e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 KXX75870.1 - 0.0046 16.5 0.1 0.019 14.5 0.0 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KXX75870.1 - 0.0051 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KXX75870.1 - 0.067 12.9 0.4 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain CAP_N PF01213.14 KXX75871.1 - 0.0098 15.2 0.8 0.011 15.0 0.6 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal MRC1 PF09444.5 KXX75872.1 - 1.2e-44 152.0 19.7 1.2e-44 152.0 13.6 7.2 6 2 2 8 8 8 1 MRC1-like domain Porin_3 PF01459.17 KXX75873.1 - 7.5e-66 222.2 8.3 8.4e-66 222.0 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.1 KXX75873.1 - 0.25 11.2 11.8 0.058 13.3 5.4 1.8 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Asn_synthase PF00733.16 KXX75874.1 - 2.7e-68 230.2 0.0 3.7e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KXX75874.1 - 1.9e-36 124.5 0.0 3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KXX75874.1 - 1e-28 99.9 0.0 2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KXX75874.1 - 4.5e-08 32.5 0.0 8.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KXX75874.1 - 0.00029 19.8 0.0 0.0011 17.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KXX75874.1 - 0.00081 18.1 0.0 0.05 12.3 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II Peptidase_M24 PF00557.19 KXX75875.1 - 2.4e-45 154.6 0.1 3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KXX75875.1 - 0.035 13.3 0.4 0.038 13.2 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_18 PF13238.1 KXX75876.1 - 1.3e-06 28.6 0.0 1.7e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX75876.1 - 2.4e-06 28.3 0.0 3.9e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KXX75876.1 - 0.00043 19.8 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KXX75876.1 - 0.00066 18.6 0.0 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 KXX75876.1 - 0.0011 18.8 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KXX75876.1 - 0.0018 17.4 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KXX75876.1 - 0.0053 16.4 0.6 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KXX75876.1 - 0.019 14.9 0.1 0.033 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KXX75876.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 KXX75876.1 - 0.041 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 KXX75876.1 - 0.046 14.0 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KXX75876.1 - 0.15 11.4 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase DnaJ PF00226.26 KXX75878.1 - 6.1e-20 70.7 0.4 9.6e-20 70.0 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain PRELI PF04707.9 KXX75879.1 - 1.6e-42 144.7 0.3 2e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 KXX75879.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain 2OG-FeII_Oxy_3 PF13640.1 KXX75880.1 - 1.5e-08 35.0 0.0 2.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldo_ket_red PF00248.16 KXX75882.1 - 2.9e-67 226.4 0.0 3.3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC1 PF03109.11 KXX75883.1 - 3.8e-30 104.2 0.0 6.5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family MFS_1 PF07690.11 KXX75884.1 - 2.4e-31 108.7 59.0 3.6e-31 108.1 40.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX75884.1 - 4.3e-10 38.7 17.9 4.3e-10 38.7 12.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_76 PF03663.9 KXX75885.1 - 2.5e-152 507.5 9.4 3.2e-152 507.2 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KXX75885.1 - 0.0021 17.1 5.7 0.072 12.1 0.1 3.0 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Spc97_Spc98 PF04130.8 KXX75886.1 - 1.3e-118 396.6 0.1 1.7e-118 396.2 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family SAGA-Tad1 PF12767.2 KXX75887.1 - 9.6e-58 195.8 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit UQ_con PF00179.21 KXX75888.1 - 5.4e-50 168.4 0.1 6.1e-50 168.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX75888.1 - 3.3e-05 23.6 0.0 4.2e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX75888.1 - 0.023 14.5 1.7 0.059 13.2 1.1 1.9 1 1 0 1 1 1 0 RWD domain SKG6 PF08693.5 KXX75889.1 - 7.1e-08 31.6 4.9 7.1e-08 31.6 3.4 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF3609 PF12259.3 KXX75889.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) VSP PF03302.8 KXX75889.1 - 0.017 13.7 0.2 0.017 13.7 0.2 1.7 2 0 0 2 2 2 0 Giardia variant-specific surface protein Amidohydro_4 PF13147.1 KXX75891.1 - 2.8e-08 34.1 1.6 4e-08 33.6 1.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KXX75891.1 - 1.4e-06 28.1 0.3 3.3e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX75891.1 - 0.0023 17.6 0.3 0.0031 17.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Fungal_trans PF04082.13 KXX75892.1 - 1.9e-28 99.0 0.0 3.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75892.1 - 5.7e-06 26.1 15.4 9.6e-06 25.4 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 KXX75892.1 - 0.014 15.7 0.2 0.014 15.7 0.1 2.2 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) WSC PF01822.14 KXX75893.1 - 3.3e-16 58.9 9.0 5.5e-16 58.2 6.2 1.4 1 0 0 1 1 1 1 WSC domain DnaJ PF00226.26 KXX75894.1 - 2.5e-27 94.3 2.5 4e-27 93.7 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KXX75894.1 - 4.6e-22 77.7 0.0 3.6e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KXX75894.1 - 1.5e-13 50.6 17.9 1.5e-13 50.6 12.4 1.6 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 KXX75894.1 - 0.002 17.8 9.4 0.062 12.9 1.7 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KXX75894.1 - 0.91 9.8 7.7 40 4.6 5.0 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2614 PF11023.3 KXX75894.1 - 2.4 7.9 5.7 13 5.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Ank_2 PF12796.2 KXX75895.1 - 5.3e-21 74.7 0.0 1.9e-10 40.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75895.1 - 3.9e-17 61.1 0.1 3.4e-05 23.4 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KXX75895.1 - 3.5e-15 56.0 0.2 0.00027 21.3 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.7 KXX75895.1 - 4.4e-09 36.2 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 KXX75895.1 - 3.2e-08 33.0 0.1 0.04 14.1 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KXX75895.1 - 2e-07 31.0 0.4 0.016 15.4 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 KXX75895.1 - 3.7e-07 30.3 0.0 9.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX75895.1 - 0.0005 20.1 1.2 0.0024 17.8 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KXX75895.1 - 0.0032 17.3 4.7 0.43 10.4 0.0 3.7 3 1 1 4 4 4 1 Alpha/beta hydrolase family AAA PF00004.24 KXX75895.1 - 0.0038 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX75895.1 - 0.019 15.8 0.2 0.07 13.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX75895.1 - 0.029 14.6 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 KXX75895.1 - 0.032 13.2 2.7 0.4 9.6 0.1 2.7 2 1 1 3 3 3 0 KAP family P-loop domain RNA_helicase PF00910.17 KXX75895.1 - 0.033 14.3 0.0 0.14 12.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KXX75895.1 - 0.034 14.0 0.0 0.21 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 KXX75895.1 - 0.12 11.1 0.0 0.52 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Mito_carr PF00153.22 KXX75897.1 - 4.9e-67 221.6 0.3 3e-21 74.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.4 KXX75898.1 - 2.2e-51 173.6 0.3 2.2e-51 173.6 0.2 2.4 3 0 0 3 3 3 1 Apolipoprotein O Med3 PF11593.3 KXX75898.1 - 2.5 7.2 10.1 3.1 6.9 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M3 PF01432.15 KXX75899.1 - 5.4e-118 394.9 0.0 9.7e-118 394.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KXX75899.1 - 0.018 14.4 0.2 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like HEAT_2 PF13646.1 KXX75899.1 - 0.3 11.3 3.1 18 5.7 0.3 2.9 2 1 0 2 2 2 0 HEAT repeats IMS PF00817.15 KXX75900.1 - 5.6e-41 139.7 0.0 1.2e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX75900.1 - 2.2e-17 63.1 0.0 5.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KXX75900.1 - 1.6e-12 47.2 13.1 3.9e-07 29.9 1.9 3.8 2 2 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KXX75900.1 - 0.00015 21.6 1.3 0.00049 19.9 0.1 2.5 2 0 0 2 2 2 1 IMS family HHH motif MgtE_N PF03448.12 KXX75900.1 - 0.0012 19.0 0.1 12 6.3 0.0 4.2 4 0 0 4 4 4 1 MgtE intracellular N domain HHH_5 PF14520.1 KXX75900.1 - 0.011 15.9 0.1 0.048 13.8 0.1 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain BRCT PF00533.21 KXX75900.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 KXX75900.1 - 0.089 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FliG_M PF14841.1 KXX75900.1 - 0.089 12.8 0.7 44 4.1 0.0 3.8 4 0 0 4 4 4 0 FliG middle domain RED_N PF07808.8 KXX75901.1 - 1.1e-09 37.8 11.3 1.1e-09 37.8 7.9 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region TRAP_alpha PF03896.11 KXX75902.1 - 1.1 8.2 4.4 1.8 7.5 3.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 KXX75902.1 - 1.7 6.6 4.3 2.9 5.8 3.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.20 KXX75903.1 - 6.8e-35 120.4 0.0 1e-20 73.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75903.1 - 1.6e-11 43.7 0.0 5.3e-10 38.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX75903.1 - 1.7e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX75903.1 - 0.0032 16.4 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like IU_nuc_hydro PF01156.14 KXX75904.1 - 3.1e-78 263.1 0.0 3.6e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1660 PF07874.6 KXX75905.1 - 0.098 12.9 0.7 5.8 7.2 0.0 2.9 2 1 0 2 2 2 0 Prophage protein (DUF1660) CAP_GLY PF01302.20 KXX75906.1 - 5.9e-17 61.1 0.2 1.6e-16 59.7 0.2 1.8 1 0 0 1 1 1 1 CAP-Gly domain AAA_13 PF13166.1 KXX75906.1 - 0.00092 17.8 7.7 0.00092 17.8 5.4 2.0 1 1 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 KXX75906.1 - 0.012 15.8 6.5 0.085 13.1 1.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KXX75906.1 - 0.023 12.0 19.5 0.039 11.2 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med4 PF10018.4 KXX75906.1 - 0.031 13.6 20.9 0.042 13.2 1.5 3.2 3 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 KXX75906.1 - 0.077 12.1 2.3 4.8 6.2 0.5 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KXX75906.1 - 0.11 11.1 22.9 0.28 9.7 5.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Nsp1_C PF05064.8 KXX75906.1 - 0.23 11.0 8.7 4.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region Pkip-1 PF06878.6 KXX75906.1 - 0.31 10.8 7.1 3.5 7.5 0.2 2.3 1 1 1 2 2 2 0 Pkip-1 protein Phage_GP20 PF06810.6 KXX75906.1 - 0.41 10.0 16.0 0.09 12.2 2.1 3.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KXX75906.1 - 0.53 10.0 4.6 0.84 9.4 1.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 KXX75906.1 - 1.5 9.1 15.8 0.1 12.9 1.9 3.8 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 KXX75906.1 - 2 8.6 17.2 0.06 13.4 3.5 3.5 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.18 KXX75906.1 - 2.3 6.9 7.7 6.1 5.6 0.2 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain Cauli_AT PF03233.8 KXX75906.1 - 3 7.5 4.4 1.4 8.5 1.0 2.0 2 0 0 2 2 2 0 Aphid transmission protein Glutaredoxin2_C PF04399.8 KXX75906.1 - 3.1 7.3 6.3 8.9 5.9 0.9 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain TPR_MLP1_2 PF07926.7 KXX75906.1 - 3.9 7.2 26.5 0.13 11.9 9.0 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.8 KXX75906.1 - 4.4 7.2 15.2 0.24 11.2 3.3 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.8 KXX75906.1 - 5.4 6.3 5.5 1.8 7.9 1.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region Glyco_hydro_38 PF01074.17 KXX75907.1 - 1.8e-91 306.2 0.5 4.5e-91 304.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KXX75907.1 - 2.4e-74 250.7 0.0 6.6e-74 249.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KXX75907.1 - 4.1e-26 91.0 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Nop14 PF04147.7 KXX75908.1 - 4.8e-272 904.7 26.2 5.7e-272 904.5 18.1 1.0 1 0 0 1 1 1 1 Nop14-like family MutS_V PF00488.16 KXX75909.1 - 6e-78 261.4 0.0 1e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KXX75909.1 - 2.9e-39 134.9 5.7 5.3e-39 134.1 4.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KXX75909.1 - 5e-19 68.3 0.0 1.9e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KXX75909.1 - 1.7e-10 41.1 0.0 3.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_22 PF13401.1 KXX75909.1 - 0.00039 20.5 0.1 0.41 10.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KXX75909.1 - 0.009 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MutS_IV PF05190.13 KXX75909.1 - 0.043 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.1 KXX75909.1 - 0.66 10.2 0.0 0.66 10.2 0.0 2.1 3 1 0 3 3 3 0 AAA domain WD40 PF00400.27 KXX75910.1 - 3.6e-06 26.6 0.0 0.004 16.9 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3275 PF11679.3 KXX75910.1 - 0.074 12.6 1.6 0.18 11.4 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ORC6 PF05460.8 KXX75910.1 - 0.54 9.3 9.9 0.042 12.9 1.3 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_L10 PF00466.15 KXX75911.1 - 1.2e-25 89.3 0.0 2.8e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KXX75911.1 - 1.1e-14 54.6 7.4 3.1e-14 53.1 3.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.9 KXX75911.1 - 0.037 13.5 0.2 13 5.2 0.0 3.5 4 0 0 4 4 4 0 Pox virus Ag35 surface protein VirE_N PF08800.5 KXX75911.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 VirE N-terminal domain PCI PF01399.22 KXX75912.1 - 1.4e-08 35.0 0.4 1.8e-07 31.3 0.0 2.8 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 KXX75913.1 - 4.8e-28 96.6 0.0 6.2e-28 96.3 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 KXX75914.1 - 1.1e-28 99.1 0.0 1.4e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.23 KXX75915.1 - 1.4e-44 151.8 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 KXX75916.1 - 3.9e-24 83.4 48.6 8.7e-05 22.6 0.1 11.2 11 0 0 11 11 11 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX75916.1 - 4.9e-23 79.7 46.2 0.0069 16.6 0.5 10.6 10 1 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX75916.1 - 5.9e-17 61.0 45.3 7.4e-06 26.0 0.4 11.4 11 1 0 11 11 11 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX75916.1 - 2.5e-06 27.4 23.0 5.3 7.3 0.0 9.8 11 0 0 11 11 11 2 Zinc-finger double-stranded RNA-binding DUF3246 PF11596.3 KXX75916.1 - 0.0021 17.4 5.1 0.0046 16.2 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) DUF4187 PF13821.1 KXX75916.1 - 0.0038 16.7 0.9 0.021 14.4 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-met PF12874.2 KXX75916.1 - 0.0058 16.7 19.0 4 7.7 0.1 7.4 8 0 0 8 8 8 2 Zinc-finger of C2H2 type TBX PF12598.3 KXX75916.1 - 0.2 12.0 8.8 0.55 10.6 6.1 1.7 1 0 0 1 1 1 0 T-box transcription factor PBP1_TM PF14812.1 KXX75916.1 - 0.37 11.1 5.1 0.17 12.2 0.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CHORD PF04968.7 KXX75916.1 - 0.92 9.7 18.2 11 6.3 0.5 6.1 6 1 0 6 6 6 0 CHORD IBR PF01485.16 KXX75916.1 - 5.2 7.0 17.4 0.93 9.4 0.7 5.4 3 2 3 6 6 6 0 IBR domain RNA_pol_Rpb6 PF01192.17 KXX75917.1 - 2.1e-22 78.6 0.1 3.8e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Tautomerase_3 PF14832.1 KXX75918.1 - 1.4e-49 167.6 0.0 1.5e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WSC PF01822.14 KXX75919.1 - 8.3e-33 112.1 24.2 1.5e-19 69.6 6.2 4.6 4 1 0 4 4 4 2 WSC domain SOG2 PF10428.4 KXX75919.1 - 0.22 10.1 9.3 0.33 9.5 6.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-HC5HC2H_2 PF13832.1 KXX75920.1 - 7.5e-34 116.0 8.5 7.5e-34 116.0 5.9 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KXX75920.1 - 2.5e-26 91.6 8.0 2.5e-26 91.6 5.5 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KXX75920.1 - 2e-18 67.1 0.1 1.4e-17 64.3 0.0 2.5 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KXX75920.1 - 3.2e-14 51.9 2.1 3.2e-14 51.9 1.4 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KXX75920.1 - 9.8e-08 31.5 9.7 9.8e-08 31.5 6.7 2.8 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.6 KXX75920.1 - 9.7 6.2 25.9 0.16 12.0 6.5 2.8 2 0 0 2 2 2 0 RING-like domain LRR_4 PF12799.2 KXX75921.1 - 1.2e-16 59.8 2.1 9.5e-07 28.3 0.9 4.4 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX75921.1 - 2.5e-13 49.5 2.7 4.5e-09 35.9 1.3 2.9 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KXX75921.1 - 6.6e-09 34.5 5.4 0.34 11.0 0.3 6.3 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KXX75921.1 - 7.4e-05 22.3 6.6 9 7.0 0.0 5.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KXX75921.1 - 0.0011 18.7 1.9 47 4.5 0.4 5.2 4 1 1 5 5 5 0 Leucine Rich repeat ICMT PF04140.9 KXX75922.1 - 6.8e-28 96.7 0.2 1.6e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KXX75922.1 - 6.4e-13 48.7 1.8 6.4e-13 48.7 1.2 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 KXX75922.1 - 0.00081 18.7 0.1 0.0016 17.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KXX75922.1 - 0.0076 14.8 0.1 0.014 13.9 0.1 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MBOAT PF03062.14 KXX75924.1 - 3.6e-19 69.0 22.7 5.8e-19 68.3 15.8 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KXX75924.1 - 0.006 16.6 5.1 0.006 16.6 3.6 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WD40 PF00400.27 KXX75925.1 - 1.6e-47 157.7 23.6 4.3e-08 32.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KXX75925.1 - 0.00052 18.8 0.1 0.0034 16.1 0.1 2.4 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 KXX75925.1 - 0.037 13.7 0.0 2.1 8.0 0.0 2.7 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KXX75925.1 - 0.072 11.2 0.0 0.13 10.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Zip PF02535.17 KXX75926.1 - 1.1e-32 113.3 16.0 3.1e-24 85.5 4.3 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MFS_1 PF07690.11 KXX75926.1 - 0.0026 16.5 19.9 0.066 11.9 1.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KXX75927.1 - 4.4e-08 32.5 3.1 0.0023 17.0 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KXX75927.1 - 0.00015 21.6 0.2 0.00033 20.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX75927.1 - 0.0007 18.5 0.6 0.0014 17.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX75927.1 - 0.0036 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX75927.1 - 0.024 14.4 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX75927.1 - 0.039 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KXX75927.1 - 0.042 14.2 0.6 0.088 13.2 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX75927.1 - 0.066 11.6 0.1 0.11 10.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KXX75927.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HTH_Tnp_ISL3 PF13542.1 KXX75930.1 - 0.087 12.0 4.7 0.18 11.0 3.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Mating_C PF12737.2 KXX75930.1 - 0.21 10.4 6.9 0.26 10.1 4.8 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Peptidase_S8 PF00082.17 KXX75931.1 - 9.9e-49 165.9 15.6 1.3e-48 165.5 10.8 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KXX75931.1 - 2.8e-11 43.8 0.0 6.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.17 KXX75932.1 - 2.2e-47 161.6 0.0 2.5e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.16 KXX75933.1 - 9.8e-36 123.2 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KXX75933.1 - 2.8e-17 62.0 0.0 5.3e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX75933.1 - 5.6e-12 45.4 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX75933.1 - 1.8e-09 37.3 0.0 4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 KXX75934.1 - 0.081 12.9 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SHS2_Rpb7-N PF03876.12 KXX75936.1 - 3.7e-08 33.3 0.0 6.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SpoOE-like PF09388.5 KXX75936.1 - 0.081 12.4 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein MIP-T3 PF10243.4 KXX75936.1 - 0.53 8.6 32.7 0.95 7.8 22.7 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PMI_typeI PF01238.16 KXX75937.1 - 2.2e-136 454.7 0.0 2.6e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 KXX75937.1 - 0.0059 16.3 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain DUF1325 PF07039.6 KXX75938.1 - 1.9e-25 88.9 0.0 2.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Arf PF00025.16 KXX75939.1 - 2.1e-73 245.2 0.0 2.4e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KXX75939.1 - 7.6e-14 51.3 0.0 9.3e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KXX75939.1 - 3.4e-12 45.7 1.6 2.5e-08 33.0 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KXX75939.1 - 4.7e-12 45.6 0.0 5.2e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KXX75939.1 - 1.4e-09 37.4 0.1 1.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KXX75939.1 - 8.1e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KXX75939.1 - 0.00023 21.1 0.0 0.00052 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KXX75939.1 - 0.0044 16.1 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KXX75939.1 - 0.019 14.4 0.1 0.099 12.0 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 KXX75940.1 - 4.5e-62 209.5 0.0 6.6e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX75940.1 - 2.1e-30 105.6 0.0 1.2e-29 103.2 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX75940.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KXX75940.1 - 0.053 13.2 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 KXX75941.1 - 8.2e-117 389.9 0.0 1e-116 389.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KXX75941.1 - 0.022 13.3 0.0 0.14 10.7 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.17 KXX75942.1 - 5.4e-21 75.4 0.0 6.3e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.19 KXX75943.1 - 8e-81 271.9 23.3 1.4e-79 267.7 16.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX75943.1 - 2e-35 122.1 56.4 2.2e-29 102.2 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX75943.1 - 2.9e-08 32.3 4.0 2.9e-08 32.3 2.8 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NmrA PF05368.8 KXX75944.1 - 7.6e-35 120.2 0.0 9.9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX75944.1 - 5.5e-11 42.8 0.1 1.1e-10 41.7 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX75944.1 - 2.9e-07 29.4 0.1 4.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX75944.1 - 5.1e-06 26.1 0.1 1.1e-05 24.9 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KXX75944.1 - 2.8e-05 23.8 0.1 7.2e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KXX75944.1 - 3.1e-05 23.9 0.3 5.4e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KXX75944.1 - 0.00015 22.0 0.1 0.00038 20.7 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KXX75944.1 - 0.0016 18.3 0.1 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KXX75944.1 - 0.0025 16.8 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KXX75944.1 - 0.0038 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KXX75944.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 KXX75944.1 - 0.04 14.3 0.1 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 KXX75944.1 - 0.04 14.4 0.1 0.082 13.4 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 KXX75944.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2561 PF10812.3 KXX75945.1 - 0.024 14.2 1.1 1 8.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) AMP-binding PF00501.23 KXX75946.1 - 2.9e-67 226.8 0.1 4.7e-67 226.1 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX75946.1 - 1.5e-10 41.8 0.6 1.1e-09 39.0 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3289 PF11692.3 KXX75946.1 - 0.14 11.3 0.2 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) MFS_1 PF07690.11 KXX75947.1 - 3.3e-28 98.4 22.1 3.9e-28 98.1 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX75947.1 - 2.6e-14 52.6 10.2 4.6e-14 51.8 7.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KXX75947.1 - 2.4e-09 35.9 4.4 3.6e-09 35.3 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trypsin_2 PF13365.1 KXX75948.1 - 3.1e-17 62.6 0.0 4.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 KXX75948.1 - 0.00035 19.5 0.0 0.0014 17.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C4 Peptidase_S46 PF10459.4 KXX75948.1 - 0.034 12.5 0.0 0.39 9.0 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.8 KXX75948.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 PhoD PF09423.5 KXX75950.1 - 3e-148 494.1 4.2 3.7e-148 493.8 2.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase CorA PF01544.13 KXX75951.1 - 5.8e-24 84.6 8.6 1.9e-20 73.1 3.3 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Ank_2 PF12796.2 KXX75952.1 - 2.8e-66 219.8 4.2 8.3e-12 45.2 0.0 9.8 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KXX75952.1 - 2.4e-58 191.1 4.2 9.6e-06 25.1 0.0 13.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 KXX75952.1 - 4.8e-55 182.3 3.7 4.9e-05 23.4 0.0 12.8 9 3 3 12 12 12 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX75952.1 - 1.6e-47 159.0 5.6 1.6e-07 31.6 0.0 12.3 8 4 5 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX75952.1 - 1.5e-45 148.6 1.6 0.00098 19.1 0.0 14.5 15 0 0 15 15 15 13 Ankyrin repeat Fungal_trans PF04082.13 KXX75953.1 - 7.6e-12 44.6 0.0 1.7e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX75953.1 - 9.7e-05 22.2 8.1 9.7e-05 22.2 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lenti_VIF_2 PF07401.7 KXX75953.1 - 0.029 13.4 0.2 0.18 10.9 0.0 2.2 3 0 0 3 3 3 0 Bovine Lentivirus VIF protein Kelch_4 PF13418.1 KXX75954.1 - 2.8e-13 49.3 15.8 0.0046 16.6 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KXX75954.1 - 6.5e-12 45.0 17.6 0.00095 19.2 0.1 5.7 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KXX75954.1 - 1.6e-10 40.7 8.8 0.0036 17.2 0.1 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KXX75954.1 - 1.1e-07 31.2 14.3 0.19 11.2 0.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KXX75954.1 - 4.6e-06 26.6 13.0 0.093 12.9 0.2 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX75954.1 - 4e-05 23.1 3.4 0.54 10.1 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Herpes_gE PF02480.11 KXX75954.1 - 0.1 10.8 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1524 PF07510.6 KXX75955.1 - 1.1e-12 47.9 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) PGAP1 PF07819.8 KXX75956.1 - 4.6e-05 23.1 0.0 9.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 KXX75956.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 KXX75956.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX75956.1 - 0.0066 16.3 0.1 0.017 14.9 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KXX75956.1 - 0.051 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RdRP PF05183.7 KXX75957.1 - 1.5e-40 139.4 0.1 2.9e-40 138.5 0.1 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 KXX75957.1 - 0.0052 16.7 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX75957.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 KXX75958.1 - 2.1e-63 214.4 0.0 5.7e-62 209.7 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 SnoaL_2 PF12680.2 KXX75959.1 - 2.8e-05 24.4 0.0 4.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KXX75959.1 - 0.052 13.6 0.2 0.67 10.0 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like domain Zn_clus PF00172.13 KXX75960.1 - 8.2e-08 32.0 9.7 1.7e-07 31.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 KXX75961.1 - 1.9e-77 261.3 0.0 2.4e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EAL PF00563.15 KXX75961.1 - 0.035 13.6 0.2 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 EAL domain DIOX_N PF14226.1 KXX75962.1 - 9.7e-28 97.0 0.0 1.7e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX75962.1 - 1.4e-19 70.1 0.0 2.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 KXX75963.1 - 3.2e-12 46.2 0.1 7.9e-12 44.8 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KXX75963.1 - 0.00081 18.2 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 KXX75963.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_4 PF01565.18 KXX75964.1 - 3.9e-20 71.7 2.1 9e-20 70.5 1.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75964.1 - 7.3e-12 45.0 1.8 1.3e-11 44.1 1.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX75964.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.17 KXX75965.1 - 4e-29 101.4 0.0 6.3e-28 97.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.17 KXX75966.1 - 3.3e-23 82.4 0.1 6.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KXX75966.1 - 0.0005 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.13 KXX75967.1 - 2.2e-06 27.4 9.0 3.4e-06 26.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KXX75968.1 - 1.4e-78 264.2 0.0 2.1e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KXX75968.1 - 4.6e-74 249.1 0.0 1.4e-73 247.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KXX75968.1 - 1e-50 172.3 0.0 1.7e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 KXX75968.1 - 5.4e-48 163.0 5.3 9.9e-48 162.1 0.0 3.6 4 0 0 4 4 3 1 KR domain PS-DH PF14765.1 KXX75968.1 - 6.9e-48 163.3 0.1 1.3e-47 162.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX75968.1 - 2.7e-42 144.5 7.8 6.5e-40 136.7 0.0 5.0 5 0 0 5 5 5 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KXX75968.1 - 3.1e-41 141.7 0.2 6.9e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KXX75968.1 - 5.7e-32 110.0 0.0 1.5e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KXX75968.1 - 3.1e-29 101.6 0.0 9.1e-29 100.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KXX75968.1 - 1.3e-21 76.6 0.3 3e-11 43.3 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KXX75968.1 - 9.7e-13 48.2 0.1 5.8e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 HxxPF-repeated domain Methyltransf_12 PF08242.7 KXX75968.1 - 4.4e-11 43.1 0.0 1.9e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX75968.1 - 4.9e-09 36.1 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KXX75968.1 - 5.7e-09 35.7 0.0 7.1e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 KXX75968.1 - 3e-08 33.3 0.0 7.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX75968.1 - 1.4e-07 32.0 0.0 4.2e-06 27.3 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX75968.1 - 8.9e-06 26.1 0.0 3.1e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KXX75968.1 - 3.6e-05 22.8 0.0 8.3e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KXX75968.1 - 0.023 13.3 0.0 4.6 5.8 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KXX75968.1 - 0.055 12.5 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Tropomyosin_1 PF12718.2 KXX75968.1 - 0.15 11.8 0.3 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin like NmrA PF05368.8 KXX75968.1 - 0.25 10.5 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family FAD_binding_4 PF01565.18 KXX75969.1 - 4e-12 45.8 0.6 7.2e-12 44.9 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 KXX75970.1 - 2.1e-66 224.3 0.0 2.6e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Calci_bind_CcbP PF11535.3 KXX75970.1 - 0.11 12.7 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Calcium binding Peptidase_S9 PF00326.16 KXX75972.1 - 1.6e-42 145.1 0.0 2.7e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX75972.1 - 7.3e-12 45.2 0.1 2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX75972.1 - 1.3e-07 31.7 0.1 7e-07 29.3 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 KXX75972.1 - 0.00014 21.4 2.8 0.17 11.5 0.4 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.13 KXX75972.1 - 0.00016 21.0 0.0 0.00038 19.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 KXX75972.1 - 0.00017 21.3 0.0 0.0019 17.9 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KXX75972.1 - 0.00054 19.4 0.0 0.99 8.7 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 KXX75972.1 - 0.001 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 KXX75972.1 - 0.0031 17.0 0.0 0.064 12.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KXX75972.1 - 0.0087 15.6 0.0 0.069 12.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KXX75972.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 KXX75972.1 - 0.017 14.3 2.2 0.033 13.4 0.4 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.8 KXX75972.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 KXX75972.1 - 0.047 12.8 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DPPIV_N PF00930.16 KXX75972.1 - 0.057 11.9 0.0 0.79 8.2 0.0 2.5 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipase_GDSL_2 PF13472.1 KXX75973.1 - 2.1e-14 54.0 1.7 2.1e-14 54.0 1.1 1.9 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX75973.1 - 5.8e-09 36.1 2.7 2.4e-08 34.0 1.9 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 KXX75974.1 - 1.3e-37 129.3 49.4 2.2e-37 128.5 30.1 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX75974.1 - 2e-13 49.4 15.6 2.6e-13 49.0 10.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 KXX75975.1 - 1.7e-14 53.4 0.5 3.6e-14 52.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX75975.1 - 2.9e-06 27.1 0.2 7.4e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX75975.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf-C2H2_2 PF12756.2 KXX75976.1 - 1.8e-22 79.3 1.6 3.6e-22 78.3 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) GFA PF04828.9 KXX75977.1 - 6.9e-10 38.7 2.3 7.4e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme F-box PF00646.28 KXX75978.1 - 0.00089 18.8 0.1 0.0022 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX75978.1 - 0.0026 17.4 0.9 0.0043 16.7 0.1 1.8 2 0 0 2 2 2 1 F-box-like Methyltransf_2 PF00891.13 KXX75979.1 - 1.1e-28 100.0 0.1 1.9e-28 99.3 0.1 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KXX75979.1 - 0.00066 19.4 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4211 PF13926.1 KXX75980.1 - 1e-37 128.9 0.0 2.7e-37 127.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Aminotran_1_2 PF00155.16 KXX75981.1 - 1e-59 202.3 0.0 1.4e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KXX75981.1 - 0.019 14.1 0.0 0.041 13.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.23 KXX75982.1 - 5.1e-47 160.1 0.0 6.2e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX75982.1 - 1.2e-06 29.3 0.5 4.5e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KXX75983.1 - 5.8e-07 29.3 11.3 9e-07 28.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 KXX75984.1 - 1.4e-24 85.6 0.1 2.6e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 YEATS family Baculo_8kDa PF06096.6 KXX75984.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein Ran_BP1 PF00638.13 KXX75985.1 - 1.8e-49 166.8 0.8 3.2e-49 166.0 0.6 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KXX75985.1 - 0.00027 20.6 0.2 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 KXX75985.1 - 0.015 14.8 0.8 0.024 14.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) PS-DH PF14765.1 KXX75985.1 - 0.031 13.4 0.4 0.031 13.4 0.3 1.6 2 0 0 2 2 2 0 Polyketide synthase dehydratase RAI1 PF08652.6 KXX75985.1 - 0.14 11.9 0.2 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Chorion_2 PF03964.10 KXX75985.1 - 0.23 12.0 3.2 0.2 12.2 1.2 1.6 2 0 0 2 2 2 0 Chorion family 2 Phosducin PF02114.11 KXX75987.1 - 1.3e-11 43.7 0.3 2.9e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 Phosducin Peptidase_S10 PF00450.17 KXX75988.1 - 1.6e-131 439.2 1.1 2.1e-131 438.9 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KXX75988.1 - 2.7e-05 24.1 0.0 0.00053 19.9 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KXX75988.1 - 8.7e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide PDEase_I PF00233.14 KXX75989.1 - 2.7e-41 141.8 1.6 1.2e-38 133.2 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Ribosomal_S13 PF00416.17 KXX75990.1 - 2.5e-41 140.4 1.4 3.1e-41 140.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KXX75990.1 - 0.0065 15.0 0.0 0.007 14.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 KXX75990.1 - 0.03 14.3 0.3 0.096 12.7 0.1 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif SBDS_C PF09377.5 KXX75991.1 - 6.6e-54 180.9 0.0 9.6e-54 180.3 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KXX75991.1 - 9.9e-30 102.1 0.1 1.6e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UCH PF00443.24 KXX75992.1 - 8.4e-74 248.0 0.0 9.6e-73 244.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX75992.1 - 4.2e-15 55.9 0.0 6.5e-08 32.3 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KXX75992.1 - 0.00012 22.4 0.0 0.00036 20.8 0.0 1.9 1 0 0 1 1 1 1 DUSP domain SAM_2 PF07647.12 KXX75993.1 - 4.6e-16 58.4 0.0 9.1e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX75993.1 - 6.9e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KXX75993.1 - 8.8e-14 51.7 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain DUF4173 PF13777.1 KXX75995.1 - 2.1 7.5 10.7 1.4 8.1 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) Aldo_ket_red PF00248.16 KXX75996.1 - 5.3e-13 48.4 0.0 8.4e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_60s PF00428.14 KXX75996.1 - 0.00061 20.1 0.7 0.0052 17.1 0.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein ATP_bind_4 PF01902.12 KXX75996.1 - 0.071 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 ATP-binding region 4F5 PF04419.9 KXX75997.1 - 1.2e-10 41.8 11.7 1.2e-10 41.8 8.1 2.5 1 1 1 2 2 2 1 4F5 protein family FKBP_N PF01346.13 KXX75997.1 - 5.8 6.9 12.1 4.2 7.4 7.4 1.5 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase CTD_bind PF04818.8 KXX75998.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 KXX75998.1 - 0.033 13.6 2.1 0.56 9.7 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 VHS PF00790.14 KXX75998.1 - 0.091 12.3 0.3 0.44 10.1 0.0 2.1 2 1 0 2 2 2 0 VHS domain zf-C2H2_4 PF13894.1 KXX75998.1 - 0.12 12.7 2.8 3.9 8.0 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3811 PF11656.3 KXX75998.1 - 0.43 10.6 2.5 1.9 8.5 0.1 2.9 2 1 1 3 3 3 0 YjbD family (DUF3811) zf-C2HC_2 PF13913.1 KXX75998.1 - 9.6 6.0 9.3 2.2 8.0 0.8 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Myb_DNA-binding PF00249.26 KXX76000.1 - 3.4e-12 46.2 2.2 5.1e-09 36.0 0.0 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX76000.1 - 1.4e-07 31.5 2.5 0.00011 22.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SMN PF06003.7 KXX76001.1 - 0.022 13.8 9.1 0.36 9.8 0.5 3.0 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) GFO_IDH_MocA PF01408.17 KXX76003.1 - 1.6e-19 70.5 0.2 3.1e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KXX76003.1 - 0.00094 19.5 0.1 0.0017 18.7 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.7 KXX76003.1 - 0.016 14.5 0.1 31 3.8 0.0 3.4 4 0 0 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system GFO_IDH_MocA_C PF02894.12 KXX76003.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_11 PF08241.7 KXX76004.1 - 5.1e-12 46.1 0.0 1.4e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76004.1 - 3.4e-08 33.8 0.0 7.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX76004.1 - 5.2e-08 33.1 0.1 1.7e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX76004.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76004.1 - 4.2e-05 23.1 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76004.1 - 4.7e-05 23.9 0.1 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Chorion_2 PF03964.10 KXX76004.1 - 1.3 9.6 20.1 0.17 12.4 0.8 3.1 3 0 0 3 3 3 0 Chorion family 2 Citrate_synt PF00285.16 KXX76005.1 - 1.1e-102 343.3 0.0 1.7e-102 342.8 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KXX76005.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone RRM_5 PF13893.1 KXX76006.1 - 7.2e-08 32.1 0.2 1.3e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX76006.1 - 2.1e-07 30.4 0.1 3.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX76006.1 - 2.1e-06 27.6 0.1 4.8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KXX76006.1 - 0.00084 19.5 0.0 0.0035 17.5 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase II-binding domain. E1-E2_ATPase PF00122.15 KXX76007.1 - 1.8e-62 210.3 7.9 1.8e-62 210.3 5.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KXX76007.1 - 4.2e-23 82.8 0.0 8.8e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX76007.1 - 2.9e-13 50.4 0.0 1.1e-12 48.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX76007.1 - 2e-10 39.9 0.2 5.8e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KXX76007.1 - 0.0012 18.4 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX76007.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Mito_carr PF00153.22 KXX76008.1 - 2.7e-29 100.6 5.5 5.1e-13 48.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3425 PF11905.3 KXX76009.1 - 1.9e-27 95.8 0.2 3.6e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KXX76009.1 - 0.052 13.5 9.7 0.11 12.5 6.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor FGGY_C PF02782.11 KXX76010.1 - 7.8e-49 165.9 0.1 1.1e-48 165.4 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KXX76010.1 - 3.3e-12 46.2 0.2 5.5e-09 35.6 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Nic96 PF04097.9 KXX76011.1 - 1.4e-217 723.6 0.0 1.8e-217 723.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 zf-C2H2_4 PF13894.1 KXX76012.1 - 1.9e-07 30.9 14.5 0.086 13.2 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger Raptor_N PF14538.1 KXX76012.1 - 0.00092 19.0 0.0 0.006 16.4 0.0 2.3 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-TRAF PF02176.13 KXX76012.1 - 0.0038 17.5 1.4 0.0038 17.5 0.9 2.1 3 0 0 3 3 3 1 TRAF-type zinc finger Peptidase_C14 PF00656.17 KXX76012.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Caspase domain zf-C2H2 PF00096.21 KXX76012.1 - 0.033 14.5 22.6 0.2 12.0 1.1 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX76012.1 - 8.6 6.8 13.0 7.5 7.0 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double domain ThuA PF06283.6 KXX76013.1 - 2.2e-61 207.3 0.0 2.5e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 KXX76013.1 - 0.00082 18.7 0.0 0.0029 16.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1355) Abhydrolase_3 PF07859.8 KXX76014.1 - 5.3e-21 75.1 0.1 9e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX76014.1 - 9e-11 41.3 0.0 1.5e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX76014.1 - 1.7e-08 34.3 0.0 3.7e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX76014.1 - 1.6e-07 31.4 2.6 3.9e-07 30.1 1.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KXX76014.1 - 0.0015 17.3 0.0 0.0046 15.7 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 KXX76014.1 - 0.023 14.1 0.0 0.8 9.1 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 KXX76014.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme CBM_1 PF00734.13 KXX76015.1 - 5.8e-10 38.6 10.9 5.8e-10 38.6 7.6 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 KXX76015.1 - 0.0014 17.1 0.0 0.0023 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF212 PF02681.9 KXX76015.1 - 0.44 10.2 1.4 0.64 9.7 0.1 1.9 2 0 0 2 2 2 0 Divergent PAP2 family Bestrophin PF01062.16 KXX76016.1 - 1.9e-43 148.4 1.1 2.2e-41 141.7 0.8 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aminotran_5 PF00266.14 KXX76018.1 - 5.4e-39 133.9 0.0 1.3e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.13 KXX76019.1 - 1.3e-16 60.2 24.1 2.3e-08 33.7 4.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX76019.1 - 3.6e-16 58.8 0.3 5.2e-16 58.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.15 KXX76020.1 - 3.8e-63 212.6 0.0 1e-62 211.2 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KXX76020.1 - 2.8e-30 104.7 0.3 2.2e-27 95.3 0.2 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KXX76020.1 - 4.7e-25 87.3 0.5 4.7e-25 87.3 0.4 1.9 2 0 0 2 2 2 1 WGR domain BRCT PF00533.21 KXX76020.1 - 2.1e-14 53.4 0.0 3.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KXX76020.1 - 2.1e-09 37.0 0.0 4.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain PTPS PF01242.14 KXX76020.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Suf PF05843.9 KXX76020.1 - 1.3 8.6 5.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Dicty_REP PF05086.7 KXX76020.1 - 4.2 4.9 4.2 6.1 4.4 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM191C PF15194.1 KXX76021.1 - 0.31 10.9 5.1 0.28 11.0 0.6 2.8 3 0 0 3 3 3 0 TMEM191C family Glyco_hydro_31 PF01055.21 KXX76023.1 - 7.7e-175 581.9 0.3 9.3e-175 581.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX76023.1 - 5e-11 42.3 1.9 4.4e-10 39.2 1.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_6 PF01341.12 KXX76024.1 - 1.4e-103 346.4 0.1 1.7e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KXX76024.1 - 4.4e-15 55.0 15.3 1.1e-14 53.7 10.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KXX76024.1 - 0.041 13.9 5.4 0.11 12.5 3.8 1.7 1 0 0 1 1 1 0 Toxin 7 PLDc_2 PF13091.1 KXX76025.1 - 1.6e-20 73.1 0.0 1.3e-12 47.5 0.0 2.7 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KXX76025.1 - 6.1e-05 22.6 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif SpoIIE PF07228.7 KXX76025.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF2183 PF09949.4 KXX76026.1 - 2.2e-30 104.5 0.0 5.7e-30 103.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) UvdE PF03851.9 KXX76027.1 - 1e-115 385.5 0.0 1.3e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Cupin_2 PF07883.6 KXX76028.1 - 3.2e-16 58.6 0.2 5.6e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KXX76028.1 - 1.5e-05 24.4 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KXX76028.1 - 7.2e-05 22.4 0.1 9.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 KXX76028.1 - 9.1e-05 22.4 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KXX76028.1 - 0.0004 20.0 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KXX76028.1 - 0.0012 18.1 0.1 0.0021 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 KXX76028.1 - 0.0068 15.4 0.2 0.03 13.3 0.0 2.0 1 1 2 3 3 3 1 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 KXX76028.1 - 0.0084 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase GST_C_3 PF14497.1 KXX76029.1 - 2e-10 41.0 0.0 3.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX76029.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX76029.1 - 4e-05 23.4 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX76029.1 - 0.00052 20.1 0.0 0.0047 17.0 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_hydro_43 PF04616.9 KXX76030.1 - 7.5e-35 120.3 0.6 9e-35 120.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Nucleos_tra2_C PF07662.8 KXX76031.1 - 1.3e-66 224.0 0.4 1.3e-66 224.0 0.2 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KXX76031.1 - 8.3e-21 74.1 2.6 8.3e-21 74.1 1.8 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus HET PF06985.6 KXX76032.1 - 1.1e-26 93.6 1.4 9.5e-26 90.6 0.8 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.9 KXX76033.1 - 5.8e-43 147.0 3.8 6.6e-43 146.8 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HET PF06985.6 KXX76034.1 - 9.9e-35 119.7 0.0 2e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PNK3P PF08645.6 KXX76035.1 - 1.3e-55 187.2 0.0 1.9e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KXX76035.1 - 3.2e-31 108.1 0.0 1.7e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KXX76035.1 - 0.0011 18.1 0.0 0.016 14.3 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin APS_kinase PF01583.15 KXX76035.1 - 0.0092 15.6 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 KXX76035.1 - 0.024 15.4 0.0 0.054 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX76035.1 - 0.024 14.1 0.0 0.081 12.4 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX76035.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KXX76035.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX76035.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 KXX76035.1 - 0.2 10.8 0.0 8.3 5.5 0.0 2.3 1 1 0 2 2 2 0 Chromatin associated protein KTI12 Sugar_tr PF00083.19 KXX76036.1 - 1.5e-102 343.5 19.8 1.8e-102 343.2 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX76036.1 - 6.2e-27 94.2 29.6 1.5e-24 86.3 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KXX76037.1 - 7.5e-19 68.2 4.2 1.2e-18 67.5 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX76037.1 - 4.6e-11 42.7 0.8 7.4e-11 42.0 0.6 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX76037.1 - 0.013 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KXX76037.1 - 0.022 14.2 0.5 0.062 12.7 0.4 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KXX76037.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 KXX76038.1 - 2.1e-59 201.0 0.0 2.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX76038.1 - 5.1e-32 111.1 0.1 9.1e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX76038.1 - 1.1e-08 34.3 0.2 1.4e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KXX76038.1 - 7.8e-06 25.8 0.4 2.9e-05 24.0 0.1 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX76038.1 - 0.00016 20.6 0.7 0.013 14.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX76038.1 - 0.00028 19.9 0.1 0.00041 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KXX76038.1 - 0.016 15.2 0.3 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX76038.1 - 0.037 12.4 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KXX76038.1 - 0.058 12.4 0.1 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KXX76038.1 - 0.25 10.2 0.0 1.4 7.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) BBE PF08031.7 KXX76040.1 - 1.8e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KXX76041.1 - 8.3e-17 60.9 0.8 1.8e-16 59.8 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX76041.1 - 5.7e-13 48.5 0.1 1.5e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX76041.1 - 0.064 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_10 PF00331.15 KXX76043.1 - 1.1e-95 320.3 0.1 1.3e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.19 KXX76043.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel WI12 PF07107.6 KXX76043.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 Wound-induced protein WI12 Hemerythrin PF01814.18 KXX76044.1 - 2.8e-09 37.2 1.6 5.7e-09 36.2 0.6 1.8 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain DUF3014 PF11219.3 KXX76044.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) ILVD_EDD PF00920.16 KXX76045.1 - 3.4e-153 510.7 0.2 3.9e-153 510.6 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.2 KXX76046.1 - 2.7e-16 60.1 3.0 3.9e-16 59.6 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX76046.1 - 1.3e-09 37.9 0.1 3.4e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX76046.1 - 0.00015 21.3 0.0 0.00096 18.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KXX76046.1 - 0.0041 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KXX76046.1 - 0.0043 16.2 0.1 0.0079 15.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.7 KXX76046.1 - 0.057 12.2 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.17 KXX76047.1 - 2e-50 171.6 0.0 2.6e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KXX76048.1 - 1.3e-60 205.0 0.0 1.7e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX76048.1 - 0.00054 20.2 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KXX76048.1 - 0.00083 19.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX76048.1 - 0.00092 18.2 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX76048.1 - 0.002 17.1 0.0 0.005 15.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KXX76048.1 - 0.0041 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX76048.1 - 0.0044 16.7 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KXX76048.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX76048.1 - 0.033 13.0 2.4 0.034 13.0 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KXX76048.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KXX76048.1 - 0.16 12.0 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain But2 PF09792.4 KXX76049.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain FAD_binding_4 PF01565.18 KXX76050.1 - 4.4e-21 74.8 0.2 8.5e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX76050.1 - 2.5e-05 24.1 0.1 6.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cupin_4 PF08007.7 KXX76052.1 - 0.069 12.3 0.0 0.078 12.2 0.0 1.0 1 0 0 1 1 1 0 Cupin superfamily protein HasA PF06438.7 KXX76053.1 - 0.056 12.8 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) UbiA PF01040.13 KXX76054.1 - 5.3e-25 88.1 25.6 8.4e-25 87.4 17.5 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Spore_YtrH PF14034.1 KXX76054.1 - 0.061 13.2 0.5 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Sporulation protein YtrH FAD_binding_4 PF01565.18 KXX76055.1 - 9.2e-28 96.4 1.1 1.9e-27 95.3 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX76055.1 - 0.036 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like PP-binding PF00550.20 KXX76057.1 - 4.4e-12 46.0 0.1 6.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KXX76057.1 - 1e-05 25.4 0.2 1.3e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 KXX76057.1 - 0.16 12.1 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) zf-CCCH PF00642.19 KXX76058.1 - 3.5e-10 39.3 8.2 3.9e-05 23.2 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KXX76058.1 - 0.18 11.8 17.5 0.25 11.3 3.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Fer4 PF00037.22 KXX76060.1 - 3.8e-14 51.5 16.4 5.3e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KXX76060.1 - 3.8e-12 46.3 11.0 6e-12 45.7 7.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KXX76060.1 - 2.3e-10 41.0 6.8 0.0002 22.0 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KXX76060.1 - 7.2e-10 38.5 21.9 2.5e-08 33.5 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KXX76060.1 - 8.9e-10 38.6 11.0 1.7e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KXX76060.1 - 2e-09 37.1 32.6 5.6e-06 26.1 8.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KXX76060.1 - 1.1e-08 34.9 31.5 7.4e-06 25.9 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KXX76060.1 - 3.3e-08 32.9 15.0 0.00043 20.0 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KXX76060.1 - 8.6e-08 31.7 17.0 0.00051 19.7 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KXX76060.1 - 4.1e-06 26.6 13.1 0.00044 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KXX76060.1 - 5e-06 26.7 10.3 0.00046 20.4 7.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KXX76060.1 - 1.9e-05 25.0 9.9 0.0045 17.3 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KXX76060.1 - 0.01 16.2 14.9 0.32 11.4 2.9 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 KXX76060.1 - 0.018 15.5 13.1 0.32 11.5 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KXX76060.1 - 0.036 14.6 17.7 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KXX76060.1 - 0.13 12.3 4.9 0.29 11.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Dynamin_N PF00350.18 KXX76061.1 - 1.3e-21 77.1 0.1 7.6e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KXX76061.1 - 4.9e-13 48.5 0.1 1.4e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KXX76061.1 - 1.9e-05 24.6 0.0 0.00019 21.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 KXX76061.1 - 0.00068 19.4 0.7 0.00068 19.4 0.5 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 KXX76061.1 - 0.004 17.6 0.0 0.21 12.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein bPH_6 PF10756.4 KXX76061.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial PH domain AAA_29 PF13555.1 KXX76061.1 - 0.051 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX76061.1 - 0.055 13.4 0.5 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KXX76061.1 - 0.99 9.6 0.0 0.99 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain HR1 PF02185.11 KXX76061.1 - 7.2 6.4 8.6 1.5 8.5 1.6 2.7 2 1 0 2 2 2 0 Hr1 repeat Peptidase_S64 PF08192.6 KXX76062.1 - 0.037 12.3 0.0 0.063 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 AMP-binding PF00501.23 KXX76066.1 - 1.6e-22 79.4 0.0 1.7e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Gly_transf_sug PF04488.10 KXX76067.1 - 2.1e-13 50.5 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 KXX76069.1 - 2.8e-49 167.6 0.0 3.4e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX76069.1 - 1.2e-18 67.8 0.4 3.4e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain tRNA-synt_1e PF01406.14 KXX76070.1 - 4.8e-111 370.6 0.2 1.1e-110 369.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KXX76070.1 - 0.00031 19.5 0.2 0.55 8.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KXX76070.1 - 0.0006 20.0 0.9 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 DALR domain adh_short PF00106.20 KXX76071.1 - 1.1e-33 116.4 2.4 1.7e-33 115.9 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76071.1 - 3.6e-16 59.6 0.6 4.3e-16 59.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76071.1 - 1.6e-10 40.9 0.7 3.2e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX76071.1 - 1.7e-05 24.4 0.3 2.3e-05 23.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX76071.1 - 0.00071 19.2 0.7 0.0011 18.6 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KXX76071.1 - 0.0019 17.1 0.2 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 KXX76071.1 - 0.0042 16.7 0.3 0.0068 16.0 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 KXX76071.1 - 0.0051 15.5 0.1 0.0069 15.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KXX76071.1 - 0.01 14.7 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KXX76071.1 - 0.014 14.6 0.5 0.025 13.8 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 KXX76071.1 - 0.014 15.7 0.5 0.029 14.7 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KXX76071.1 - 0.016 15.1 0.2 0.026 14.5 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KXX76071.1 - 0.03 13.4 0.2 0.062 12.4 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KXX76071.1 - 0.032 13.3 0.1 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KXX76071.1 - 0.042 13.6 1.5 0.17 11.7 0.9 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Enoyl_reductase PF12241.3 KXX76071.1 - 0.078 11.9 0.2 0.61 9.0 0.0 2.0 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region NAD_binding_10 PF13460.1 KXX76071.1 - 0.084 12.8 0.5 0.19 11.6 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding Lipocalin_2 PF08212.7 KXX76072.1 - 1.2e-14 54.3 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 KXX76072.1 - 0.00012 22.1 0.0 0.00018 21.4 0.0 1.3 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Polysacc_lyase PF14099.1 KXX76073.1 - 3.7e-39 134.7 8.1 4.3e-39 134.4 5.6 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Peptidase_MA_2 PF13485.1 KXX76074.1 - 0.0057 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Nuc_sug_transp PF04142.10 KXX76076.1 - 1.1e-77 260.4 8.8 1.6e-77 259.9 6.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KXX76076.1 - 8e-09 34.8 15.1 1.8e-07 30.3 10.2 2.2 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KXX76076.1 - 6.1e-05 22.7 24.4 0.022 14.4 2.2 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KXX76076.1 - 8.8e-05 22.5 25.7 0.00012 22.1 3.2 3.1 2 2 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KXX76076.1 - 0.013 15.6 1.7 0.013 15.6 1.2 2.7 2 0 0 2 2 2 0 Multidrug resistance efflux transporter NDUFA12 PF05071.11 KXX76077.1 - 2e-24 86.0 0.6 2.7e-24 85.6 0.4 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4188 PF13826.1 KXX76077.1 - 0.072 13.1 0.7 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) Crp PF00325.15 KXX76077.1 - 0.25 10.8 0.2 0.25 10.8 0.1 1.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family PLDc_2 PF13091.1 KXX76078.1 - 1.3e-14 54.0 0.0 2.3e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KXX76078.1 - 1.2e-07 31.2 1.5 0.036 13.8 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif HAUS-augmin3 PF14932.1 KXX76079.1 - 0.097 11.8 20.3 0.055 12.6 7.0 3.8 2 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.6 KXX76079.1 - 0.2 11.5 8.7 0.38 10.6 0.5 4.0 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KXX76079.1 - 2.3 8.3 8.5 9.1 6.3 0.1 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family STAT_alpha PF01017.15 KXX76079.1 - 2.6 7.7 14.2 0.38 10.4 3.9 3.5 3 1 1 4 4 4 0 STAT protein, all-alpha domain DUF1319 PF07028.6 KXX76079.1 - 4.4 7.5 14.4 1.3 9.2 0.3 4.0 5 1 0 5 5 5 0 Protein of unknown function (DUF1319) Adeno_E1B_19K PF01691.11 KXX76081.1 - 0.15 11.3 0.8 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen DUF418 PF04235.7 KXX76081.1 - 0.73 9.4 9.4 0.91 9.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF418) GMC_oxred_N PF00732.14 KXX76082.1 - 5.6e-67 225.9 0.0 7.2e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX76082.1 - 4.5e-29 101.5 0.0 8.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX76082.1 - 2.5e-05 23.3 0.3 0.0025 16.7 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX76082.1 - 0.0032 17.4 0.0 0.0089 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX76082.1 - 0.0052 15.6 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KXX76082.1 - 0.018 13.9 0.1 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KXX76082.1 - 0.11 12.2 0.2 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KXX76082.1 - 0.31 10.0 1.8 0.62 9.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Mito_carr PF00153.22 KXX76085.1 - 2.1e-70 232.4 1.8 3.3e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_3 PF13302.1 KXX76086.1 - 8e-32 110.3 0.0 9.6e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KXX76086.1 - 2.6e-07 30.7 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX76086.1 - 3e-06 27.1 0.0 7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX76086.1 - 2.3e-05 24.3 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Serine_rich PF08824.5 KXX76087.1 - 0.015 14.9 0.4 0.022 14.5 0.3 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain MxiH PF09392.5 KXX76087.1 - 2 9.0 6.4 3.5 8.2 4.4 1.4 1 0 0 1 1 1 0 Type III secretion needle MxiH like F-box-like PF12937.2 KXX76088.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like PNTB PF02233.11 KXX76089.1 - 5.1e-157 523.3 38.1 1.8e-153 511.6 13.0 2.7 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KXX76089.1 - 1e-54 184.5 1.1 1.9e-54 183.7 0.7 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KXX76089.1 - 2.2e-48 163.7 1.1 3.2e-48 163.1 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KXX76089.1 - 3.1e-31 107.3 3.3 3.1e-31 107.3 2.3 5.9 5 2 2 7 7 7 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KXX76089.1 - 0.00055 19.1 0.1 0.59 9.2 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KXX76089.1 - 0.0022 17.5 0.3 0.0085 15.6 0.2 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KXX76089.1 - 0.005 16.4 0.0 0.027 14.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Fumerase PF05681.9 KXX76089.1 - 0.0056 15.7 0.2 0.0097 15.0 0.1 1.3 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Pyr_redox_2 PF07992.9 KXX76089.1 - 0.013 15.3 0.7 0.043 13.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KXX76089.1 - 0.027 15.0 0.0 0.075 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KXX76089.1 - 0.27 11.3 4.9 13 5.8 0.0 4.3 6 1 0 6 6 5 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KXX76089.1 - 8.2 6.5 9.0 0.88 9.6 1.8 2.9 3 1 0 3 3 2 0 NAD(P)-binding Rossmann-like domain FSH1 PF03959.8 KXX76090.1 - 5.6e-32 110.9 0.0 6.4e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX76090.1 - 6e-06 26.2 3.3 4.1e-05 23.5 2.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX76090.1 - 0.0021 17.8 0.4 0.0041 16.8 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX76090.1 - 0.17 11.3 0.1 14 5.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Acyl_transf_3 PF01757.17 KXX76092.1 - 4.1e-22 78.4 21.5 1.2e-21 76.8 14.6 2.0 1 1 1 2 2 2 1 Acyltransferase family zf-C3HC4_2 PF13923.1 KXX76094.1 - 3.6e-08 33.2 1.6 3.6e-08 33.2 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX76094.1 - 2.1e-07 30.6 5.6 5.3e-07 29.3 3.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX76094.1 - 2.5e-05 23.8 3.8 2.5e-05 23.8 2.7 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX76094.1 - 5.3e-05 22.8 3.1 6.5e-05 22.5 1.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX76094.1 - 0.00017 21.6 1.9 0.00017 21.6 1.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KXX76094.1 - 0.00061 19.4 3.6 0.00061 19.4 2.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KXX76094.1 - 0.0087 15.7 4.0 0.054 13.2 0.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KXX76094.1 - 0.042 13.7 0.6 0.042 13.7 0.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KXX76094.1 - 0.099 12.4 0.6 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 KXX76094.1 - 0.2 11.3 2.1 0.3 10.8 1.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.6 KXX76094.1 - 4.5 7.3 8.1 2 8.4 1.7 2.4 2 0 0 2 2 2 0 RING-like domain WD40 PF00400.27 KXX76095.1 - 1.9e-56 186.0 21.1 1.1e-09 37.8 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KXX76095.1 - 2.3e-11 43.2 0.3 7.1e-10 38.4 0.2 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KXX76095.1 - 1.2e-08 34.4 0.1 5.1e-08 32.3 0.0 2.2 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KXX76095.1 - 4e-07 28.5 3.3 0.32 9.0 0.0 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 YmzC PF14157.1 KXX76095.1 - 0.18 11.6 0.0 49 3.8 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein DASH_Dad4 PF08650.5 KXX76096.1 - 5.9e-28 96.5 5.8 6.4e-28 96.4 4.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 KXX76096.1 - 0.065 12.9 3.7 0.081 12.6 2.6 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 GM_CSF PF01109.12 KXX76096.1 - 0.071 13.0 0.5 0.082 12.8 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 KXX76096.1 - 0.1 11.6 0.4 0.11 11.5 0.3 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Biotin_carb_C PF02785.14 KXX76096.1 - 0.12 12.4 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DUF3221 PF11518.3 KXX76096.1 - 0.14 11.8 1.2 0.16 11.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) V-SNARE_C PF12352.3 KXX76096.1 - 0.26 11.3 1.7 0.4 10.7 0.7 1.6 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus FA_hydroxylase PF04116.8 KXX76097.1 - 2.9e-16 59.8 16.6 2.9e-16 59.8 11.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 KXX76098.1 - 5.1e-27 93.4 0.2 6.6e-27 93.1 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.16 KXX76099.1 - 3.4e-08 33.3 7.8 1.4e-07 31.3 5.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX76099.1 - 0.63 9.8 9.3 26 4.7 6.5 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.14 KXX76100.1 - 1.5e-56 191.5 0.0 6.2e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Actin IR1-M PF12185.3 KXX76100.1 - 0.011 15.4 0.6 0.039 13.6 0.4 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Ras PF00071.17 KXX76101.1 - 3.4e-65 218.3 0.0 4.4e-65 217.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX76101.1 - 1.4e-19 70.7 0.0 2.1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX76101.1 - 4e-13 48.9 0.0 4.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX76101.1 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KXX76101.1 - 7.9e-06 25.1 0.0 8.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KXX76101.1 - 0.0042 17.0 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX76101.1 - 0.015 14.5 0.0 0.073 12.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 KXX76101.1 - 0.021 14.0 0.0 0.065 12.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KXX76101.1 - 0.025 13.7 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 KXX76101.1 - 0.091 12.3 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX76101.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 KXX76101.1 - 0.15 10.6 0.4 16 4.0 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Strumpellin PF10266.4 KXX76101.1 - 0.18 9.1 0.0 0.22 8.9 0.0 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin NCA2 PF08637.5 KXX76102.1 - 9.4e-90 300.4 0.0 1.5e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TAP42 PF04177.7 KXX76104.1 - 1.4e-105 353.0 0.0 1.6e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DsbB PF02600.11 KXX76105.1 - 0.089 12.5 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Ribonuclease_3 PF00636.21 KXX76106.1 - 9.7e-38 129.1 0.2 2.6e-18 66.5 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX76106.1 - 1.4e-21 76.7 0.0 8.8e-09 35.4 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KXX76106.1 - 3.6e-21 74.7 0.1 1e-19 70.1 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KXX76106.1 - 4.6e-13 48.8 0.1 1.1e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX76106.1 - 1.6e-10 41.0 0.0 3.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KXX76106.1 - 1.5e-09 37.6 0.0 3.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX76106.1 - 0.089 12.9 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain PNPOx_C PF10590.4 KXX76107.1 - 5.3e-21 73.8 2.7 3.6e-20 71.1 2.4 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KXX76107.1 - 1.8e-11 43.8 0.0 1.2e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KXX76107.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 KXX76108.1 - 1.8e-14 54.0 3.6 5.2e-14 52.5 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KXX76108.1 - 8.9e-08 31.9 0.4 2.4e-07 30.5 0.0 1.9 2 1 1 3 3 3 1 KR domain Epimerase PF01370.16 KXX76108.1 - 5.4e-07 29.2 0.0 9.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX76108.1 - 0.0009 18.9 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KXX76108.1 - 0.001 18.8 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX76108.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding E1-N PF14463.1 KXX76108.1 - 0.0032 17.0 0.1 0.0087 15.6 0.0 1.8 1 1 1 2 2 2 1 E1 N-terminal domain DAO PF01266.19 KXX76108.1 - 0.034 13.0 0.1 0.075 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ldh_1_N PF00056.18 KXX76108.1 - 0.077 12.8 0.0 13 5.6 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.11 KXX76108.1 - 0.095 12.1 0.5 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DUF3792 PF12670.2 KXX76108.1 - 0.33 10.8 2.5 0.28 11.0 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Sec63 PF02889.11 KXX76110.1 - 2.8e-149 496.5 0.0 8.8e-95 317.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KXX76110.1 - 1.1e-52 177.9 0.1 3.7e-28 98.1 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX76110.1 - 3.3e-17 62.0 0.0 1.1e-06 28.4 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KXX76110.1 - 7.8e-15 55.1 0.0 4.8e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX76110.1 - 2.6e-07 30.8 0.1 0.037 14.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KXX76110.1 - 4e-07 29.6 0.3 0.024 14.3 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 KXX76110.1 - 1.9e-05 23.6 0.1 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_30 PF13604.1 KXX76110.1 - 6.8e-05 22.5 0.0 0.06 12.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KXX76110.1 - 0.00046 20.4 0.1 2.6 8.2 0.0 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX76110.1 - 0.0025 17.2 0.2 0.28 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KXX76110.1 - 0.018 14.4 0.1 15 4.9 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KXX76110.1 - 0.047 12.7 0.1 1.4 8.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin G-patch PF01585.18 KXX76111.1 - 1.2e-07 31.3 0.1 2.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Remorin_N PF03766.8 KXX76111.1 - 0.031 14.0 0.6 0.094 12.5 0.4 1.9 1 0 0 1 1 1 0 Remorin, N-terminal region Peptidase_C12 PF01088.16 KXX76112.1 - 8.8e-36 123.0 0.0 5e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Synaptobrevin PF00957.16 KXX76114.1 - 8.7e-31 105.3 0.0 1.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KXX76114.1 - 6.5e-21 73.6 0.0 9.8e-21 73.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.3 KXX76115.1 - 4.3e-16 58.0 2.0 5.9e-16 57.6 0.5 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KXX76115.1 - 2e-07 30.7 0.0 5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 KXX76115.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase adh_short PF00106.20 KXX76116.1 - 3.3e-30 105.1 1.4 3.3e-30 105.1 1.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76116.1 - 6.4e-24 85.0 0.0 7.8e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76116.1 - 1.7e-18 66.8 0.6 1.7e-18 66.8 0.4 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX76116.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Proteasome PF00227.21 KXX76117.1 - 9.2e-25 87.0 0.0 1.8e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit DUF2567 PF10821.3 KXX76117.1 - 0.0061 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) FMN_dh PF01070.13 KXX76118.1 - 1.5e-103 346.4 0.0 1.9e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KXX76118.1 - 8.8e-22 76.7 0.0 3.2e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KXX76118.1 - 2e-06 26.9 0.0 0.00036 19.5 0.0 3.0 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KXX76118.1 - 4.4e-06 25.8 0.1 6.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KXX76118.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 KXX76118.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ATP11 PF06644.6 KXX76118.1 - 0.056 12.9 0.8 0.089 12.2 0.0 1.6 2 0 0 2 2 2 0 ATP11 protein Ribul_P_3_epim PF00834.14 KXX76118.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family SNF2_N PF00176.18 KXX76119.1 - 6e-31 107.3 0.0 1.7e-29 102.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX76119.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX76119.1 - 0.2 11.4 0.0 22 4.8 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit LRR_4 PF12799.2 KXX76120.1 - 0.025 14.2 4.0 12 5.6 0.4 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX76120.1 - 0.025 14.3 1.6 0.1 12.3 0.4 2.4 2 0 0 2 2 2 0 Leucine rich repeat Chlor_dismutase PF06778.7 KXX76120.1 - 0.086 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Chlorite dismutase HCNGP PF07818.8 KXX76121.1 - 6.4e-20 70.9 0.0 1.3e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 HCNGP-like protein SIS PF01380.17 KXX76122.1 - 2e-57 192.4 0.1 5.9e-30 103.5 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KXX76122.1 - 1.3e-27 96.5 0.0 1.1e-18 67.0 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KXX76122.1 - 3.3e-20 72.3 0.0 8.4e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KXX76122.1 - 4.3e-11 42.6 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KXX76122.1 - 1.8e-06 26.8 0.0 3.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KXX76122.1 - 0.0028 17.3 0.0 0.31 10.7 0.0 2.6 2 0 0 2 2 2 1 SIS domain AAA PF00004.24 KXX76123.1 - 1.7e-42 144.7 0.0 3.1e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX76123.1 - 4.1e-07 30.1 0.1 7.1e-06 26.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KXX76123.1 - 1e-05 25.2 0.1 0.00012 21.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX76123.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KXX76123.1 - 1.6e-05 25.0 0.0 0.0014 18.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX76123.1 - 2.1e-05 23.7 0.0 3.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX76123.1 - 0.00062 19.4 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KXX76123.1 - 0.00071 18.5 0.0 0.0018 17.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF4200 PF13863.1 KXX76123.1 - 0.00081 19.3 1.4 0.0018 18.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_17 PF13207.1 KXX76123.1 - 0.0018 19.0 0.0 0.0066 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KXX76123.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KXX76123.1 - 0.0048 15.6 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KXX76123.1 - 0.0048 17.1 0.1 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX76123.1 - 0.0058 16.5 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KXX76123.1 - 0.0064 15.9 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KXX76123.1 - 0.0079 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KXX76123.1 - 0.0086 15.6 0.1 0.8 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KXX76123.1 - 0.012 15.9 0.8 5.5 7.2 0.5 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KXX76123.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KXX76123.1 - 0.014 14.5 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fungal_trans_2 PF11951.3 KXX76123.1 - 0.015 13.8 0.0 0.015 13.8 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain AAA_28 PF13521.1 KXX76123.1 - 0.018 15.0 0.4 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KXX76123.1 - 0.024 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX76123.1 - 0.024 14.0 0.1 0.12 11.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KXX76123.1 - 0.029 13.8 0.0 0.078 12.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KXX76123.1 - 0.045 13.3 0.1 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KXX76123.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 KXX76123.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KXX76123.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 KXX76123.1 - 0.092 11.8 0.0 0.29 10.2 0.0 1.8 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 KXX76123.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KXX76123.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KXX76123.1 - 0.21 10.4 0.0 0.42 9.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3712 PF12505.3 KXX76124.1 - 5.3e-26 91.0 0.4 5.3e-26 91.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Lactamase_B_2 PF12706.2 KXX76125.1 - 5.5e-27 94.5 0.0 6.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KXX76125.1 - 5.8e-13 48.8 0.0 7.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Protoglobin PF11563.3 KXX76126.1 - 2.4e-59 199.5 0.1 2.8e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Gln-synt_C PF00120.19 KXX76127.1 - 3.5e-57 193.4 0.0 5.1e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KXX76127.1 - 2.9e-16 58.8 0.0 5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Zn_clus PF00172.13 KXX76128.1 - 1.6e-05 24.7 7.5 3.3e-05 23.6 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX76128.1 - 2e-05 23.3 0.2 2.8e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KXX76129.1 - 2.3e-12 46.9 6.9 3.4e-11 43.0 4.8 2.1 1 1 0 1 1 1 1 RTA1 like protein Epimerase PF01370.16 KXX76130.1 - 3.8e-20 72.3 0.0 5.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KXX76130.1 - 4.9e-11 42.0 0.0 5.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KXX76130.1 - 1.7e-10 40.2 1.4 4.6e-07 29.0 0.1 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KXX76130.1 - 1.5e-07 30.3 0.0 7.5e-07 28.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX76130.1 - 4.7e-06 25.7 0.5 3.8e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein NAD_binding_10 PF13460.1 KXX76130.1 - 0.00064 19.7 0.1 0.0013 18.7 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KXX76130.1 - 0.02 14.5 0.8 4 7.0 0.1 2.1 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 KXX76130.1 - 0.029 14.2 4.5 1.3 8.9 0.2 2.2 1 1 0 2 2 2 0 short chain dehydrogenase HTH_21 PF13276.1 KXX76131.1 - 0.0086 16.0 4.3 0.051 13.5 3.0 2.0 1 1 0 1 1 1 1 HTH-like domain HSCB_C PF07743.8 KXX76132.1 - 3.3e-19 69.1 2.9 8.6e-19 67.7 1.3 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KXX76132.1 - 3.5e-07 29.8 0.0 8.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Lamp PF01299.12 KXX76132.1 - 0.35 9.9 7.5 2.6 7.1 0.1 2.1 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) PAP1 PF08601.5 KXX76132.1 - 1.7 8.2 4.5 2.5 7.7 3.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PCI PF01399.22 KXX76133.1 - 2.8e-11 43.6 0.0 3.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 KXX76133.1 - 2.8e-05 23.5 0.2 9.3e-05 21.8 0.1 1.8 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.1 KXX76134.1 - 8.2e-23 81.4 0.0 9.9e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX76134.1 - 0.0001 22.2 0.2 0.0051 16.6 0.1 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Imm-NTF2 PF15655.1 KXX76135.1 - 0.11 12.9 0.1 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 NTF2 fold immunity protein Cytomega_gL PF01801.11 KXX76136.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L KAT11 PF08214.6 KXX76137.1 - 2.1e-88 296.7 0.0 2.7e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein SET PF00856.23 KXX76138.1 - 4.4e-12 46.5 0.0 2.8e-11 43.9 0.0 2.2 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KXX76138.1 - 4.9e-06 26.4 0.1 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Metallophos_2 PF12850.2 KXX76139.1 - 0.071 12.9 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SET PF00856.23 KXX76141.1 - 2.2e-15 57.3 0.0 4.1e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 SET domain MFS_1 PF07690.11 KXX76143.1 - 5.3e-35 120.7 28.4 2.5e-33 115.2 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX76143.1 - 1.2e-12 47.1 23.7 1.9e-12 46.5 16.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3366 PF11846.3 KXX76143.1 - 0.015 15.2 1.1 4.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) HTH_38 PF13936.1 KXX76143.1 - 0.052 13.1 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain YfhO PF09586.5 KXX76143.1 - 0.32 8.9 2.4 0.57 8.1 1.1 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF1049 PF06305.6 KXX76143.1 - 1.6 8.2 3.9 45 3.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF4064 PF13273.1 KXX76143.1 - 9.1 6.4 14.3 7.5 6.7 0.2 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) SRP54 PF00448.17 KXX76144.1 - 4.5e-76 254.6 1.8 1.7e-75 252.7 0.3 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KXX76144.1 - 1.5e-25 89.4 8.0 1.5e-25 89.4 5.6 3.9 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 KXX76144.1 - 2.6e-12 46.6 0.1 7.1e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KXX76144.1 - 8.6e-09 35.0 0.1 3.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KXX76144.1 - 5.5e-08 32.7 0.1 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KXX76144.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KXX76144.1 - 2.4e-05 25.1 0.0 5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KXX76144.1 - 7.5e-05 22.2 0.1 0.00029 20.3 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 KXX76144.1 - 0.00098 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_31 PF13614.1 KXX76144.1 - 0.0013 18.6 0.0 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KXX76144.1 - 0.0022 16.8 3.3 0.0036 16.1 0.5 2.4 2 1 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KXX76144.1 - 0.0025 17.9 0.0 0.0094 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX76144.1 - 0.0031 17.5 0.2 0.011 15.7 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KXX76144.1 - 0.0039 16.4 0.9 1.8 7.7 0.5 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 KXX76144.1 - 0.0045 16.3 0.3 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.7 KXX76144.1 - 0.0056 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 KXX76144.1 - 0.0081 16.3 0.2 0.044 13.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KXX76144.1 - 0.009 15.5 0.1 0.037 13.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KXX76144.1 - 0.0094 16.2 0.0 0.021 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KXX76144.1 - 0.01 15.2 0.1 0.022 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 KXX76144.1 - 0.014 14.0 0.0 0.032 12.8 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 KXX76144.1 - 0.015 15.2 0.0 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KXX76144.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KXX76144.1 - 0.038 13.0 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.1 KXX76144.1 - 0.049 13.3 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Arf PF00025.16 KXX76144.1 - 0.063 12.5 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 1 0 ADP-ribosylation factor family Abhydrolase_5 PF12695.2 KXX76144.1 - 0.071 12.8 0.0 0.8 9.4 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirE PF05272.6 KXX76144.1 - 0.077 12.4 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E Torsin PF06309.6 KXX76144.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 Torsin ABC_tran PF00005.22 KXX76144.1 - 0.13 12.5 1.1 0.39 11.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter ABM PF03992.11 KXX76145.1 - 0.00024 21.0 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GSDH PF07995.6 KXX76146.1 - 5.6e-09 35.5 0.2 9.2e-09 34.8 0.1 1.4 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SBP_bac_3 PF00497.15 KXX76147.1 - 1.5e-06 27.6 0.0 6.7e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 KXX76147.1 - 1.4e-05 24.6 0.0 5.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3834 PF12916.2 KXX76147.1 - 0.028 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) IpaD PF06511.6 KXX76147.1 - 0.045 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD NMT1 PF09084.6 KXX76147.1 - 0.062 12.8 0.0 0.39 10.2 0.0 2.2 1 1 0 1 1 1 0 NMT1/THI5 like Ribonucleas_3_3 PF14622.1 KXX76148.1 - 1.8e-30 105.5 0.0 3.9e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KXX76148.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Peroxidase_2 PF01328.12 KXX76150.1 - 1.7e-32 112.3 0.1 2.2e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Aldo_ket_red PF00248.16 KXX76151.1 - 8.3e-47 159.3 0.1 1.9e-46 158.1 0.1 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KXX76152.1 - 2.4e-27 95.6 44.5 1.9e-26 92.6 30.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX76152.1 - 2.2e-16 59.1 12.2 2.8e-16 58.8 8.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CHAP PF05257.11 KXX76153.1 - 4e-22 78.1 6.1 4e-22 78.1 4.2 1.9 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.6 KXX76153.1 - 9.2e-05 22.5 0.3 0.00021 21.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Phage_lysozyme PF00959.14 KXX76154.1 - 1.1e-12 48.1 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.6 KXX76154.1 - 7.3e-06 26.0 1.4 1.6e-05 24.9 0.6 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 KXX76154.1 - 0.046 13.2 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain Sugar_tr PF00083.19 KXX76155.1 - 6.5e-91 305.1 29.1 8.9e-91 304.7 20.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX76155.1 - 4.6e-29 101.2 57.5 2.4e-27 95.5 22.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX76155.1 - 1.5e-06 26.7 1.0 1.5e-06 26.7 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KXX76157.1 - 2.2e-18 66.0 0.0 3.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX76157.1 - 3.4e-05 23.6 9.0 6.5e-05 22.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1631 PF07793.6 KXX76157.1 - 0.093 10.8 1.1 0.2 9.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4662 PF15578.1 KXX76158.1 - 0.27 10.7 0.1 1.1 8.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) zf-A20 PF01754.11 KXX76159.1 - 0.033 13.7 3.0 0.055 13.0 1.1 2.2 2 0 0 2 2 2 0 A20-like zinc finger Pkinase PF00069.20 KXX76160.1 - 5.3e-44 150.3 0.0 1.1e-43 149.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76160.1 - 5.3e-31 107.6 0.0 7.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KXX76160.1 - 0.0092 15.0 0.0 0.024 13.6 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KXX76160.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GMC_oxred_C PF05199.8 KXX76161.1 - 3.5e-36 124.6 0.0 5.9e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KXX76161.1 - 2.6e-23 82.6 0.0 4.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DUF4124 PF13511.1 KXX76162.1 - 0.063 13.3 0.9 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Sulfotransfer_3 PF13469.1 KXX76163.1 - 0.067 14.1 0.5 0.16 12.9 0.3 1.6 1 1 0 1 1 1 0 Sulfotransferase family SIS PF01380.17 KXX76163.1 - 0.17 11.4 0.0 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 SIS domain GMC_oxred_N PF00732.14 KXX76164.1 - 1.7e-17 63.5 0.1 3.1e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 GMC oxidoreductase HET PF06985.6 KXX76165.1 - 1.1e-20 74.2 1.6 1.9e-19 70.2 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) COesterase PF00135.23 KXX76166.1 - 1.7e-84 284.4 0.2 6.1e-75 252.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX76166.1 - 3.6e-10 39.7 0.0 7.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX76166.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX76166.1 - 0.0041 17.0 0.1 0.007 16.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX76166.1 - 0.031 13.7 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KXX76166.1 - 0.084 12.0 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_10 PF13460.1 KXX76167.1 - 1.3e-05 25.2 0.2 3.5e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KXX76167.1 - 8.5e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KXX76167.1 - 0.0063 16.2 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KXX76167.1 - 0.0066 15.7 0.1 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 KXX76167.1 - 0.03 13.4 0.0 2.3 7.3 0.0 2.3 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) ApbA PF02558.11 KXX76167.1 - 0.045 13.1 0.3 0.063 12.7 0.2 1.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KXX76167.1 - 0.082 13.3 0.2 0.2 12.0 0.1 1.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 KXX76167.1 - 0.096 12.4 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Dodecin PF07311.7 KXX76167.1 - 0.13 12.2 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Dodecin Lig_chan PF00060.21 KXX76168.1 - 2 8.1 6.3 0.69 9.6 0.5 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel Yippee-Mis18 PF03226.9 KXX76169.1 - 7.4e-23 80.4 0.5 8.4e-23 80.2 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 KXX76169.1 - 0.0031 17.4 1.0 0.051 13.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zf-CHY PF05495.7 KXX76169.1 - 0.065 13.4 1.2 7.2 6.8 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger Cytochrome_C554 PF13435.1 KXX76169.1 - 0.073 13.1 1.5 0.15 12.0 1.1 1.5 1 1 0 1 1 1 0 Cytochrome c554 and c-prime NAD_binding_6 PF08030.7 KXX76170.1 - 1.9e-20 73.3 0.0 9.9e-18 64.5 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KXX76170.1 - 1.1e-19 70.7 11.7 1.1e-19 70.7 8.1 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KXX76170.1 - 2e-14 53.3 0.0 6.1e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain DUF1180 PF06679.7 KXX76170.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2985 PF11204.3 KXX76171.1 - 1.1e-35 121.2 3.7 1.1e-35 121.2 2.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.10 KXX76172.1 - 5.7e-07 28.8 0.1 1.5e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KXX76172.1 - 4.6e-06 26.6 26.4 4.1e-05 23.6 1.8 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF872 PF05915.7 KXX76172.1 - 0.00031 20.5 0.2 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) TPT PF03151.11 KXX76172.1 - 0.0087 15.7 16.6 0.21 11.2 0.9 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family Aminotran_3 PF00202.16 KXX76173.1 - 1.1e-73 247.9 0.0 1.4e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III EB_dh PF09459.5 KXX76173.1 - 0.13 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Trypan_PARP PF05887.6 KXX76174.1 - 0.39 10.5 10.4 0.96 9.2 7.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CLU PF13236.1 KXX76175.1 - 4.2e-82 274.8 0.0 6.7e-82 274.1 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KXX76175.1 - 1.8e-50 171.1 0.6 5.6e-50 169.5 0.0 2.2 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KXX76175.1 - 4.2e-30 103.5 16.4 4.8e-11 42.4 0.0 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 KXX76175.1 - 2.2e-24 85.3 0.1 4.8e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KXX76175.1 - 7.1e-18 63.9 3.2 0.00068 19.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF727 PF05303.7 KXX76175.1 - 5e-05 23.0 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_11 PF13414.1 KXX76175.1 - 7.5e-05 22.3 8.4 0.14 11.8 0.9 3.6 1 1 3 4 4 4 4 TPR repeat Vfa1 PF08432.5 KXX76175.1 - 0.1 12.6 15.7 0.33 10.9 10.9 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Apc3 PF12895.2 KXX76175.1 - 0.11 12.6 4.0 11 6.2 0.1 3.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KXX76175.1 - 0.25 11.2 2.0 0.53 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX76175.1 - 0.29 11.4 2.5 1.3e+02 3.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SAPS PF04499.10 KXX76175.1 - 0.31 9.6 2.9 0.49 8.9 2.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 KXX76175.1 - 0.75 9.5 8.0 0.13 11.9 2.5 2.0 2 0 0 2 2 2 0 DDHD domain TPR_2 PF07719.12 KXX76175.1 - 0.91 9.5 12.5 0.78 9.8 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat NPR3 PF03666.8 KXX76175.1 - 1.2 7.5 5.4 2.2 6.7 3.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TPR_16 PF13432.1 KXX76175.1 - 2.2 9.0 8.9 2 9.2 0.5 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat Fork_head PF00250.13 KXX76176.1 - 1.1e-33 115.0 0.2 2e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KXX76176.1 - 4.2e-06 26.7 0.0 8.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain NfeD PF01957.13 KXX76176.1 - 0.22 11.6 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding zf-C2H2_4 PF13894.1 KXX76177.1 - 3.8e-08 33.1 11.0 0.0007 19.7 1.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX76177.1 - 2.6e-07 30.5 9.5 0.0055 16.9 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX76177.1 - 0.0019 18.3 13.2 0.83 10.0 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 KXX76177.1 - 1.6 8.9 6.8 0.37 10.9 0.6 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding KAAG1 PF15354.1 KXX76178.1 - 1.2 9.4 5.3 8.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Kidney-associated antigen 1 EnY2 PF10163.4 KXX76179.1 - 0.028 14.3 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 Transcription factor e(y)2 AAA PF00004.24 KXX76180.1 - 1.6e-98 326.0 0.0 8.9e-48 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KXX76180.1 - 2e-19 69.3 1.2 4.7e-19 68.1 0.3 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KXX76180.1 - 5.2e-14 51.8 0.0 3.4e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KXX76180.1 - 7.3e-14 52.0 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KXX76180.1 - 4.8e-13 49.0 0.5 9.2e-07 28.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KXX76180.1 - 1.6e-12 47.4 0.0 1.6e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX76180.1 - 3.1e-12 46.7 0.3 0.00066 19.8 0.1 4.2 2 2 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KXX76180.1 - 1e-11 45.1 0.0 0.00029 20.9 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KXX76180.1 - 4.1e-11 43.7 0.0 0.00032 21.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX76180.1 - 2.1e-09 37.0 4.6 0.014 14.7 0.0 4.7 2 2 2 4 4 4 3 AAA domain TIP49 PF06068.8 KXX76180.1 - 2.2e-09 36.5 0.1 0.00084 18.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KXX76180.1 - 2.4e-08 33.9 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KXX76180.1 - 2.5e-08 33.5 1.4 0.0086 15.8 0.0 3.2 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 KXX76180.1 - 2.6e-08 33.4 0.0 0.005 16.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KXX76180.1 - 1.5e-07 30.7 0.3 0.0051 15.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KXX76180.1 - 2.3e-07 30.0 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin CDC48_2 PF02933.12 KXX76180.1 - 3.4e-07 29.7 0.0 9.7e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 KXX76180.1 - 4.2e-07 30.1 0.0 0.026 14.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KXX76180.1 - 7.8e-07 28.4 0.8 0.22 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 KXX76180.1 - 9.2e-07 28.0 0.0 0.0051 15.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) ResIII PF04851.10 KXX76180.1 - 1.3e-06 28.4 0.0 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KXX76180.1 - 1.3e-06 28.7 0.0 0.085 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KXX76180.1 - 2e-06 27.5 0.2 0.094 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 KXX76180.1 - 3.5e-06 27.0 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 KXX76180.1 - 7.2e-06 25.0 0.0 0.042 12.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KXX76180.1 - 9.8e-06 25.6 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KXX76180.1 - 1.1e-05 25.3 0.1 4.3 6.9 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activat PF00158.21 KXX76180.1 - 1.3e-05 24.7 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KXX76180.1 - 1.5e-05 24.7 0.0 0.084 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 KXX76180.1 - 2e-05 24.3 0.0 0.13 11.8 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein ABC_tran PF00005.22 KXX76180.1 - 2.7e-05 24.5 0.0 0.35 11.1 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_30 PF13604.1 KXX76180.1 - 0.00011 21.8 0.0 0.31 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KXX76180.1 - 0.00012 21.4 0.2 0.47 9.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KXX76180.1 - 0.00017 21.1 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KXX76180.1 - 0.00036 19.4 0.1 0.45 9.3 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.1 KXX76180.1 - 0.00039 20.0 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KXX76180.1 - 0.00091 18.9 0.9 0.64 9.7 0.0 4.0 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 KXX76180.1 - 0.0015 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KXX76180.1 - 0.005 15.8 0.4 1 8.2 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.13 KXX76180.1 - 0.0061 16.1 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 KXX76180.1 - 0.01 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KXX76180.1 - 0.025 14.2 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KXX76180.1 - 0.028 13.8 0.6 1.5 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KXX76180.1 - 0.033 13.1 0.0 1.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 KXX76180.1 - 0.041 13.3 0.2 12 5.2 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.11 KXX76180.1 - 0.048 12.4 0.5 5.6 5.6 0.0 2.5 3 0 0 3 3 2 0 AFG1-like ATPase AAA_23 PF13476.1 KXX76180.1 - 0.071 13.4 0.0 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KXX76180.1 - 0.09 12.6 0.1 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KXX76180.1 - 0.1 11.7 0.3 11 5.1 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 KXX76180.1 - 0.11 12.1 0.9 3.4 7.3 0.0 3.3 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B Fungal_trans_2 PF11951.3 KXX76181.1 - 1.7e-08 33.4 0.4 2.5e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX76181.1 - 0.00012 21.9 3.2 0.0002 21.1 2.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA_2 PF13911.1 KXX76182.1 - 7.4e-12 45.2 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KXX76182.1 - 8.8e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family ADH_N PF08240.7 KXX76183.1 - 2.4e-30 104.4 3.3 4e-30 103.7 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX76183.1 - 9e-17 60.8 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KXX76183.1 - 3.4e-06 26.6 0.2 1.1e-05 25.0 0.2 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Sen15 PF09631.5 KXX76184.1 - 1.9e-25 89.0 0.0 3.5e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein Toxin_YhaV PF11663.3 KXX76184.1 - 0.086 12.5 0.0 0.29 10.8 0.0 1.9 1 1 1 2 2 2 0 Toxin with endonuclease activity YhaV DPPIV_N PF00930.16 KXX76186.1 - 1e-104 349.9 2.7 1e-104 349.9 1.9 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KXX76186.1 - 3.4e-41 140.7 0.4 5.8e-41 140.0 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX76186.1 - 6.5e-08 32.4 0.2 1.7e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX76186.1 - 2.8e-05 24.0 2.1 8.8e-05 22.4 0.8 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX76186.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3809 PF12723.2 KXX76187.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) MFS_1 PF07690.11 KXX76189.1 - 5.7e-35 120.6 25.5 7.2e-35 120.3 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX76189.1 - 2.1e-09 36.4 19.1 2.2e-09 36.4 12.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KXX76189.1 - 0.004 16.9 4.2 0.0087 15.8 2.1 2.2 2 0 0 2 2 2 1 MFS_1 like family Tyrosinase PF00264.15 KXX76190.1 - 2.4e-24 86.7 4.3 2.4e-24 86.7 3.0 2.5 2 0 0 2 2 2 1 Common central domain of tyrosinase CorA PF01544.13 KXX76191.1 - 8.5e-14 51.2 0.0 2.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein E1-E2_ATPase PF00122.15 KXX76192.1 - 3.9e-59 199.4 0.3 8e-59 198.4 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX76192.1 - 4.2e-28 99.2 0.0 7e-27 95.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX76192.1 - 8.6e-18 64.0 0.0 2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX76192.1 - 4e-12 46.6 0.1 1.7e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX76192.1 - 1.1e-07 31.1 0.1 7.8e-07 28.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KXX76192.1 - 0.00083 19.0 0.2 0.0015 18.2 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KXX76192.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus SPR1 PF15356.1 KXX76192.1 - 0.22 11.9 2.0 4.9 7.5 0.6 2.3 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 WD40 PF00400.27 KXX76193.1 - 1.8e-45 151.2 16.9 1e-09 37.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KXX76193.1 - 4.9e-06 24.9 2.2 0.39 8.7 0.0 4.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box-like PF12937.2 KXX76193.1 - 5.5e-06 26.0 0.1 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 KXX76193.1 - 0.00011 21.1 0.4 0.094 11.4 0.1 3.0 3 1 0 3 3 3 2 Nup133 N terminal like F-box PF00646.28 KXX76193.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.11 KXX76193.1 - 0.0046 15.3 0.0 0.0085 14.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 KXX76193.1 - 0.0049 16.3 0.1 0.018 14.5 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain FlaG PF03646.10 KXX76193.1 - 0.083 13.0 0.0 1.5 9.0 0.0 2.7 3 0 0 3 3 3 0 FlaG protein Snapin_Pallidin PF14712.1 KXX76194.1 - 0.02 15.1 0.3 0.047 14.0 0.1 1.7 2 0 0 2 2 2 0 Snapin/Pallidin Herpes_UL51 PF04540.8 KXX76194.1 - 0.058 12.9 1.1 0.11 12.0 0.8 1.5 1 0 0 1 1 1 0 Herpesvirus UL51 protein DUF3208 PF11482.3 KXX76194.1 - 0.12 12.5 0.0 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) DUF4172 PF13776.1 KXX76194.1 - 0.36 10.9 2.0 0.68 10.0 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) DUF1996 PF09362.5 KXX76195.1 - 5.8e-90 301.0 0.5 7.7e-90 300.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 KXX76195.1 - 2.5e-12 46.2 18.3 2.5e-12 46.2 12.7 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain HCO3_cotransp PF00955.16 KXX76196.1 - 3.4e-50 171.1 14.4 4.4e-34 118.0 4.0 2.1 2 0 0 2 2 2 2 HCO3- transporter family Presenilin PF01080.12 KXX76196.1 - 0.057 12.2 3.1 0.1 11.3 2.2 1.4 1 0 0 1 1 1 0 Presenilin ABC_tran PF00005.22 KXX76197.1 - 1.9e-39 135.0 0.0 2.1e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX76197.1 - 4e-22 78.9 11.8 5.7e-22 78.4 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KXX76197.1 - 4.8e-11 42.3 1.3 0.0085 15.3 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KXX76197.1 - 8.8e-09 35.7 0.6 0.0043 17.0 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KXX76197.1 - 1e-08 34.5 1.1 0.0016 17.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX76197.1 - 1.5e-06 28.7 0.2 0.0063 16.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX76197.1 - 1.7e-05 24.9 0.1 0.16 12.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KXX76197.1 - 2e-05 24.5 0.3 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_19 PF13245.1 KXX76197.1 - 7.5e-05 22.4 0.2 0.024 14.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KXX76197.1 - 0.0001 21.8 0.9 0.0088 15.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KXX76197.1 - 0.00014 21.9 0.8 0.2 11.6 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KXX76197.1 - 0.00019 20.5 0.2 0.078 12.0 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 KXX76197.1 - 0.00025 20.2 0.3 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KXX76197.1 - 0.00035 20.0 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX76197.1 - 0.00038 21.2 0.4 1 10.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KXX76197.1 - 0.00047 19.1 0.4 0.37 9.6 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein Dynamin_N PF00350.18 KXX76197.1 - 0.00058 19.7 1.6 0.046 13.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 KXX76197.1 - 0.00093 19.5 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AIG1 PF04548.11 KXX76197.1 - 0.0017 17.4 0.7 0.54 9.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 KXX76197.1 - 0.0049 17.3 0.3 0.22 12.0 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_30 PF13604.1 KXX76197.1 - 0.005 16.4 0.2 0.41 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KXX76197.1 - 0.0053 16.2 0.2 0.77 9.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF87 PF01935.12 KXX76197.1 - 0.0059 16.4 4.7 0.014 15.1 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 KXX76197.1 - 0.0094 15.6 0.6 0.92 9.2 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KXX76197.1 - 0.012 15.1 1.4 1.8 8.0 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KXX76197.1 - 0.024 14.1 1.6 4.1 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 KXX76197.1 - 0.025 13.5 0.3 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.24 KXX76197.1 - 0.036 13.5 1.1 3.9 6.9 0.4 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.1 KXX76197.1 - 0.043 13.6 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KXX76197.1 - 0.053 13.6 0.1 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KXX76197.1 - 0.062 12.9 0.0 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 KXX76197.1 - 0.062 12.8 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KXX76197.1 - 0.067 13.4 0.2 5.9 7.1 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX76197.1 - 0.083 12.3 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KXX76197.1 - 0.16 10.9 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KXX76197.1 - 0.16 11.8 0.3 6.1 6.7 0.0 3.2 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 KXX76197.1 - 0.19 11.4 5.6 6.1 6.5 0.0 3.2 3 0 0 3 3 3 0 NTPase Herpes_Helicase PF02689.9 KXX76197.1 - 0.29 8.8 0.4 7.7 4.1 0.1 2.0 2 0 0 2 2 2 0 Helicase TrwB_AAD_bind PF10412.4 KXX76197.1 - 0.31 9.6 1.2 2.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Virul_fac_BrkB PF03631.10 KXX76197.1 - 2.8 7.2 22.9 0.065 12.5 9.7 2.1 2 0 0 2 2 2 0 Virulence factor BrkB SET PF00856.23 KXX76199.1 - 1.6e-10 41.5 0.0 7.2e-10 39.4 0.0 2.0 1 1 1 2 2 2 1 SET domain APH PF01636.18 KXX76200.1 - 6e-34 117.8 0.1 8.9e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KXX76200.1 - 0.023 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF2263 PF10021.4 KXX76201.1 - 2.7e-23 82.5 0.2 1.2e-20 74.0 0.1 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) AAA PF00004.24 KXX76202.1 - 4.6e-16 59.2 0.0 7.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX76202.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX76202.1 - 0.012 15.4 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KXX76202.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Abhydrolase_3 PF07859.8 KXX76203.1 - 1.8e-12 47.3 0.1 2.2e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KXX76204.1 - 0.16 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FAD_binding_4 PF01565.18 KXX76205.1 - 2.9e-19 68.9 0.4 2.9e-19 68.9 0.3 3.8 4 1 1 5 5 5 1 FAD binding domain BBE PF08031.7 KXX76205.1 - 2.7e-11 43.2 0.5 5.1e-11 42.2 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KXX76206.1 - 2.9e-15 56.6 0.0 3.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76206.1 - 1.4e-06 28.2 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76206.1 - 2.1e-05 24.2 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 KR domain BTG PF07742.7 KXX76206.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 BTG family Pyridox_oxidase PF01243.15 KXX76207.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GDPD PF03009.12 KXX76208.1 - 2.1e-14 53.6 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.23 KXX76208.1 - 5.5e-11 43.0 0.1 4.3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KXX76208.1 - 0.025 14.2 0.1 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 KXX76208.1 - 0.1 12.5 0.9 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KXX76209.1 - 3.4e-36 124.6 36.9 3.4e-36 124.6 25.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Methyltransf_25 PF13649.1 KXX76211.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GTP_EFTU PF00009.22 KXX76212.1 - 5.1e-46 156.4 0.0 8.2e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KXX76212.1 - 5.5e-38 129.1 5.1 8.9e-38 128.5 3.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KXX76212.1 - 1.1e-17 63.6 0.0 2.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX76212.1 - 8.3e-06 25.8 0.2 1.7e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KXX76212.1 - 6.1e-05 22.7 0.0 0.00024 20.9 0.0 2.1 2 1 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX76212.1 - 0.00034 20.5 0.0 0.00079 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KXX76212.1 - 0.0038 16.6 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 KXX76212.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Glyco_hydro_10 PF00331.15 KXX76213.1 - 3.9e-102 341.5 0.0 4.4e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KXX76213.1 - 0.018 14.6 0.1 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 KXX76213.1 - 0.08 13.4 0.0 0.38 11.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-binding cellulase-like F-box-like PF12937.2 KXX76214.1 - 1.9e-08 33.9 0.3 5.5e-08 32.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KXX76214.1 - 0.0003 20.4 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 KXX76214.1 - 0.0063 16.1 0.7 0.0063 16.1 0.5 2.8 3 1 0 3 3 3 1 F-box domain HALZ PF02183.13 KXX76214.1 - 0.052 13.2 0.3 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Clr5 PF14420.1 KXX76215.1 - 5.6e-15 54.9 0.1 5.6e-15 54.9 0.1 1.4 2 0 0 2 2 2 1 Clr5 domain zf-C2H2_2 PF12756.2 KXX76215.1 - 0.074 13.1 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NOSIC PF08060.8 KXX76215.1 - 0.095 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 NOSIC (NUC001) domain MRP-S26 PF14943.1 KXX76215.1 - 0.096 12.2 0.7 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Ank_2 PF12796.2 KXX76216.1 - 4.9e-29 100.4 3.1 2.6e-11 43.6 0.0 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76216.1 - 6.6e-21 73.0 3.6 6e-05 22.6 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 KXX76216.1 - 2.6e-20 72.3 4.2 4.5e-06 27.0 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX76216.1 - 7.1e-19 66.0 1.5 0.0028 17.7 0.0 8.3 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KXX76216.1 - 2.2e-07 30.9 4.1 1.9 8.8 0.0 6.7 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX76217.1 - 4.9e-25 87.6 2.2 3.5e-16 59.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76217.1 - 1.5e-18 65.5 7.5 0.00013 21.6 0.1 4.6 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KXX76217.1 - 1.9e-17 61.5 1.6 0.00025 20.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KXX76217.1 - 4e-17 62.2 1.6 6.2e-07 29.7 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX76217.1 - 1.3e-08 34.8 6.8 0.00066 19.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) MIT PF04212.13 KXX76218.1 - 9.5e-13 47.8 2.8 2e-12 46.7 1.9 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain NAD_binding_8 PF13450.1 KXX76219.1 - 1.8e-12 47.0 0.1 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX76219.1 - 0.00054 18.9 0.9 0.003 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX76219.1 - 0.01 15.5 0.8 0.17 11.6 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX76219.1 - 0.024 14.5 0.1 0.15 11.9 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX76219.1 - 0.03 12.9 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KXX76219.1 - 0.048 12.5 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2834 PF11196.3 KXX76220.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2834) Terpene_synth_C PF03936.11 KXX76221.1 - 1.3e-09 37.6 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HTH_29 PF13551.1 KXX76221.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn helix Methyltransf_23 PF13489.1 KXX76222.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76222.1 - 6.4e-07 29.9 0.0 1.2e-05 25.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76222.1 - 0.00017 22.0 0.0 0.002 18.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76222.1 - 0.013 15.1 0.0 0.13 11.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KXX76222.1 - 0.017 15.5 0.0 0.048 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KXX76222.1 - 0.096 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KXX76222.1 - 0.12 12.7 0.0 0.72 10.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KXX76222.1 - 0.18 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Retrotrans_gag PF03732.12 KXX76223.1 - 0.0025 17.8 0.0 0.003 17.5 0.0 1.3 1 1 0 1 1 1 1 Retrotransposon gag protein Ank_2 PF12796.2 KXX76224.1 - 1.4e-60 201.5 12.1 9.2e-15 54.7 0.1 6.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX76224.1 - 2.3e-40 135.6 11.5 2.6e-06 27.4 0.1 10.1 5 4 5 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX76224.1 - 2.6e-38 129.6 5.5 6.9e-07 29.6 0.0 9.5 3 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.25 KXX76224.1 - 1.7e-36 122.1 16.0 1.6e-07 30.7 0.0 10.9 12 0 0 12 12 11 6 Ankyrin repeat Ank_3 PF13606.1 KXX76224.1 - 4e-31 103.9 3.4 0.0073 16.4 0.0 10.8 10 0 0 10 10 10 7 Ankyrin repeat SPRY PF00622.23 KXX76224.1 - 2.1e-12 47.2 0.1 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain AAA_16 PF13191.1 KXX76224.1 - 5.8e-09 36.1 0.2 3.9e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KXX76224.1 - 1.2e-05 24.9 0.0 8.3e-05 22.2 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KXX76224.1 - 0.00047 19.8 0.2 0.0032 17.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KXX76224.1 - 0.00062 19.9 0.1 0.0024 18.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX76224.1 - 0.0012 18.2 0.4 0.048 13.0 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KXX76224.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KXX76224.1 - 0.018 15.1 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KXX76224.1 - 0.026 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 KXX76224.1 - 0.06 12.7 0.2 1 8.7 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein Rad17 PF03215.10 KXX76224.1 - 0.087 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 KXX76224.1 - 0.12 11.3 0.0 2.2 7.1 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA PF00004.24 KXX76224.1 - 0.13 12.4 0.1 0.73 10.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX76224.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-MYND PF01753.13 KXX76225.1 - 8.5e-12 44.7 13.4 2.1e-11 43.5 9.3 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KXX76225.1 - 0.045 13.6 7.5 0.12 12.2 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KXX76225.1 - 5 6.4 10.9 5.5 6.3 6.1 2.2 2 1 0 2 2 2 0 Life-span regulatory factor p450 PF00067.17 KXX76226.1 - 2.3e-50 171.4 0.0 2.9e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chromate_transp PF02417.10 KXX76227.1 - 2.9e-26 92.0 16.0 8.1e-19 67.8 4.5 2.6 3 0 0 3 3 3 2 Chromate transporter AXE1 PF05448.7 KXX76228.1 - 0.01 14.3 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAR PF03114.13 KXX76229.1 - 3.4e-64 216.5 3.4 4.2e-64 216.2 2.4 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 KXX76229.1 - 0.065 13.6 0.3 0.54 10.7 0.0 2.6 3 0 0 3 3 3 0 CP12 domain BAR PF03114.13 KXX76230.1 - 8.5e-56 189.0 3.8 1e-55 188.7 2.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KXX76230.1 - 2.6e-06 26.5 1.2 4.4e-06 25.8 0.9 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 KXX76230.1 - 0.4 9.6 6.6 0.61 9.0 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KXX76230.1 - 0.92 9.0 4.3 1.4 8.4 3.0 1.2 1 0 0 1 1 1 0 IncA protein CAP PF00188.21 KXX76232.1 - 7e-17 62.0 0.2 9.1e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family adh_short PF00106.20 KXX76234.1 - 1.1e-05 25.4 1.0 3.2e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX76234.1 - 0.00058 19.5 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KXX76234.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Aldedh PF00171.17 KXX76235.1 - 1.1e-135 452.6 0.0 1.3e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX76235.1 - 0.00063 18.5 0.0 0.0019 16.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Chitin_bind_1 PF00187.14 KXX76236.1 - 5.4e-05 23.0 20.7 5.4e-05 23.0 14.4 3.6 4 0 0 4 4 4 2 Chitin recognition protein Glyco_hydro_18 PF00704.23 KXX76237.1 - 1.4e-12 47.7 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1996 PF09362.5 KXX76239.1 - 1.1e-89 300.1 0.3 1.3e-89 299.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.11 KXX76240.1 - 1.3e-25 90.5 0.2 1.6e-25 90.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pept_tRNA_hydro PF01195.14 KXX76242.1 - 6.2e-30 104.0 0.0 7.6e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Cyclin_N PF00134.18 KXX76243.1 - 3e-05 23.6 0.0 8.3e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.21 KXX76244.1 - 2.4e-24 85.3 0.0 4.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KXX76244.1 - 4.2e-05 23.2 0.0 0.031 13.9 0.0 2.6 3 0 0 3 3 3 2 UEV domain Pkinase PF00069.20 KXX76245.1 - 1.4e-56 191.5 0.0 1.9e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76245.1 - 3.7e-25 88.4 0.1 1.6e-24 86.4 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX76245.1 - 0.021 13.8 0.1 0.049 12.5 0.0 1.6 2 0 0 2 2 2 0 Kinase-like IBN_N PF03810.14 KXX76246.1 - 2.3e-12 46.6 3.7 2.4e-10 40.1 0.0 4.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 KXX76246.1 - 2.6e-08 32.8 0.0 6e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KXX76246.1 - 2.2e-07 30.8 3.0 4.1e-05 23.5 0.1 4.6 5 0 0 5 5 5 1 Exportin 1-like protein DUF2435 PF10363.4 KXX76246.1 - 0.044 13.6 0.3 0.14 12.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KXX76246.1 - 0.045 13.6 0.1 0.21 11.3 0.0 2.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 ISN1 PF06437.6 KXX76249.1 - 1.7e-191 636.3 0.0 2e-191 636.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PV-1 PF06637.6 KXX76249.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Ribosomal_L21e PF01157.13 KXX76251.1 - 5e-40 135.3 5.3 8.9e-40 134.5 3.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3865 PF12981.2 KXX76251.1 - 0.1 12.3 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Ribosomal_S4 PF00163.14 KXX76252.1 - 3.2e-28 97.9 0.8 6.6e-28 96.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KXX76252.1 - 2.3e-13 49.3 1.7 2.3e-13 49.3 1.2 2.2 3 0 0 3 3 3 1 S4 domain Slu7 PF11708.3 KXX76253.1 - 1.6e-70 237.6 12.9 2.1e-70 237.1 8.9 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KXX76253.1 - 0.00035 20.1 0.1 0.00072 19.1 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KXX76253.1 - 0.0007 19.4 3.2 0.0012 18.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 KXX76253.1 - 0.086 12.5 4.0 0.21 11.3 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.16 KXX76254.1 - 3.5e-90 303.0 0.0 4e-81 273.1 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KXX76254.1 - 9.4e-22 77.2 0.0 2.1e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KXX76254.1 - 3.1e-14 52.7 1.9 7.3e-14 51.5 1.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.5 KXX76254.1 - 0.056 13.3 0.4 0.19 11.5 0.3 1.9 1 0 0 1 1 1 0 XkdW protein DUF3439 PF11921.3 KXX76254.1 - 0.76 9.5 9.3 1.7 8.3 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KXX76254.1 - 4.2 4.9 3.2 6.3 4.4 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gly_transf_sug PF04488.10 KXX76255.1 - 1.2e-12 48.0 0.0 3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KXX76255.1 - 0.0063 15.0 0.0 0.0094 14.4 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KXX76255.1 - 0.011 14.9 0.0 0.035 13.2 0.0 1.8 1 1 1 2 2 2 0 Capsular polysaccharide synthesis protein DUF2404 PF10296.4 KXX76256.1 - 1.5e-32 111.5 0.0 9.2e-32 109.0 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 KXX76256.1 - 0.11 12.7 0.0 0.94 9.7 0.0 2.6 2 1 0 2 2 2 0 PH domain IMS PF00817.15 KXX76257.1 - 2.4e-45 153.9 0.0 3.9e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX76257.1 - 7.5e-15 54.9 0.0 1.4e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KXX76257.1 - 0.0095 15.9 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif U-box PF04564.10 KXX76258.1 - 3.2e-21 75.0 0.0 8.2e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KXX76258.1 - 1.3e-20 72.7 6.8 2e-16 59.3 0.1 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KXX76258.1 - 2.4e-12 45.7 5.3 0.0055 16.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX76258.1 - 1.2e-11 43.7 3.2 0.0028 17.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76258.1 - 1.3e-08 35.3 10.9 2.9e-06 27.7 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX76258.1 - 6.2e-07 29.1 1.7 0.021 14.9 0.0 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76258.1 - 4.7e-06 26.8 1.3 0.0089 16.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76258.1 - 1.8e-05 24.5 9.6 0.0008 19.3 3.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76258.1 - 3.7e-05 23.9 8.0 0.019 15.5 0.1 4.3 3 1 2 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX76258.1 - 4.4e-05 23.5 0.9 0.00079 19.5 0.6 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX76258.1 - 0.00095 18.9 2.9 0.0011 18.7 0.7 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76258.1 - 0.019 14.7 2.6 1.4 8.9 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1268 PF06896.6 KXX76258.1 - 0.029 14.7 0.2 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) zf-Nse PF11789.3 KXX76258.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_20 PF14561.1 KXX76258.1 - 0.067 13.3 0.3 0.067 13.3 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX76258.1 - 0.097 12.4 0.6 13 5.8 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M28 PF04389.12 KXX76259.1 - 4.2e-26 91.7 0.1 6.3e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KXX76259.1 - 2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PLDc_2 PF13091.1 KXX76260.1 - 6.6e-17 61.4 0.0 8.8e-08 31.9 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KXX76260.1 - 0.001 18.8 0.1 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Inhibitor_Mig-6 PF11555.3 KXX76260.1 - 0.0045 17.3 2.7 0.014 15.8 1.9 1.9 1 0 0 1 1 1 1 EGFR receptor inhibitor Mig-6 Regulator_TrmB PF11495.3 KXX76260.1 - 0.12 11.2 0.1 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB F-box-like PF12937.2 KXX76261.1 - 0.00097 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX76261.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain Glyco_transf_22 PF03901.12 KXX76262.1 - 1.4e-89 301.0 20.4 1.6e-89 300.8 14.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 KXX76263.1 - 1e-44 151.7 0.1 1e-44 151.7 0.1 2.6 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Macoilin PF09726.4 KXX76263.1 - 0.44 8.7 7.0 0.61 8.3 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein SH3_9 PF14604.1 KXX76264.1 - 3.7e-11 42.4 0.3 7.9e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KXX76264.1 - 1.4e-06 27.5 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX76264.1 - 2.1e-05 23.9 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.6 KXX76264.1 - 3.4e-05 23.4 1.2 5.8e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.1 KXX76264.1 - 0.00028 19.4 0.0 0.0004 19.0 0.0 1.1 1 0 0 1 1 1 1 Amnionless Herpes_gE PF02480.11 KXX76264.1 - 0.0018 16.6 0.1 0.0027 16.0 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KXX76264.1 - 0.0067 16.1 0.5 0.012 15.3 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.7 KXX76264.1 - 0.014 14.8 0.2 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2407_C PF13373.1 KXX76264.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain Protocadherin PF08374.6 KXX76264.1 - 0.019 14.6 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Protocadherin DUF1049 PF06305.6 KXX76264.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Rifin_STEVOR PF02009.11 KXX76264.1 - 0.051 13.2 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Adeno_E3_CR2 PF02439.10 KXX76264.1 - 0.095 12.2 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KXX76264.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vpu PF00558.14 KXX76264.1 - 0.99 9.0 3.5 0.57 9.7 1.1 1.5 1 1 1 2 2 2 0 Vpu protein Glycophorin_A PF01102.13 KXX76264.1 - 4.9 6.9 11.6 31 4.3 7.6 2.5 1 1 0 1 1 1 0 Glycophorin A MtrF PF09472.5 KXX76264.1 - 5.8 6.2 7.0 9.9 5.4 4.8 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SQS_PSY PF00494.14 KXX76266.1 - 0.11 11.7 1.1 6.5 5.9 0.5 2.8 1 1 1 2 2 2 0 Squalene/phytoene synthase NPV_P10 PF05531.7 KXX76267.1 - 0.033 14.4 4.7 0.063 13.5 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AF0941-like PF14591.1 KXX76267.1 - 0.21 11.6 5.8 6.8 6.7 0.1 3.4 2 1 1 4 4 4 0 AF0941-like Vac_Fusion PF02346.11 KXX76267.1 - 0.28 10.6 2.0 1.2 8.6 0.2 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein NUC153 PF08159.7 KXX76268.1 - 2.9e-14 52.3 0.4 2.9e-14 52.3 0.3 3.2 3 0 0 3 3 3 1 NUC153 domain MHCassoc_trimer PF08831.5 KXX76269.1 - 0.038 13.8 0.2 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain SnoaL PF07366.7 KXX76269.1 - 0.13 11.7 0.1 2.5 7.6 0.0 2.2 1 1 0 2 2 2 0 SnoaL-like polyketide cyclase DUF4349 PF14257.1 KXX76271.1 - 0.22 10.7 0.8 0.34 10.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) AFG1_ATPase PF03969.11 KXX76272.1 - 3.2e-96 322.3 0.0 6.9e-91 304.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KXX76272.1 - 5.4e-06 26.5 0.1 0.0066 16.4 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 KXX76272.1 - 0.0014 18.5 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX76272.1 - 0.0018 18.4 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX76272.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KXX76272.1 - 0.0029 17.2 0.4 0.26 10.8 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 KXX76272.1 - 0.0091 16.0 0.0 0.14 12.2 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KXX76272.1 - 0.0094 15.6 0.0 0.034 13.8 0.0 2.0 2 1 0 2 2 2 1 NACHT domain AAA PF00004.24 KXX76272.1 - 0.036 14.2 0.0 0.24 11.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KXX76272.1 - 0.055 13.6 0.2 0.21 11.8 0.0 2.1 2 1 0 2 2 2 0 RNA helicase Acetyltransf_7 PF13508.1 KXX76273.1 - 1.8e-07 31.2 0.1 5.8e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX76273.1 - 4.7e-06 26.5 0.4 0.00041 20.3 0.0 3.0 4 0 0 4 4 4 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KXX76273.1 - 1.8e-05 24.5 0.1 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX76273.1 - 0.015 15.0 0.1 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 KXX76273.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cpn60_TCP1 PF00118.19 KXX76274.1 - 6.6e-144 480.1 13.5 7.5e-144 479.9 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 KXX76275.1 - 8.1e-21 74.3 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KXX76275.1 - 3.4e-20 71.7 0.2 7e-20 70.7 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KXX76275.1 - 4.5e-16 58.5 0.0 9.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Exo5 PF09810.4 KXX76276.1 - 5.1e-104 347.9 0.0 6.8e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KXX76276.1 - 7.7e-05 22.1 2.3 0.00015 21.2 0.2 2.4 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Ferric_reduct PF01794.14 KXX76277.1 - 1.4e-16 60.6 14.6 1.4e-16 60.6 10.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KXX76277.1 - 1.5e-15 57.4 0.0 6.1e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KXX76277.1 - 6e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KXX76277.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DM13 PF10517.4 KXX76278.1 - 5.1e-12 46.1 0.0 7.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 ketoacyl-synt PF00109.21 KXX76280.1 - 1e-72 244.6 0.0 1.8e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX76280.1 - 4.2e-46 157.7 0.0 8.9e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 KXX76280.1 - 2.9e-41 142.1 0.0 7.6e-40 137.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KXX76280.1 - 1.4e-34 118.4 0.5 4.7e-34 116.7 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KXX76280.1 - 9.3e-23 80.2 2.3 3.5e-10 39.9 0.3 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KXX76280.1 - 1.5e-12 47.2 0.0 6.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KXX76280.1 - 2.9e-11 43.6 4.4 0.00033 20.6 0.0 4.1 4 0 0 4 4 4 3 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX76280.1 - 4.8e-06 26.3 0.2 0.15 11.8 0.0 3.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KXX76280.1 - 0.0026 16.7 0.1 0.0059 15.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DNA_pol_E_B PF04042.11 KXX76281.1 - 1.2e-67 227.2 0.0 1.7e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Cu-oxidase_2 PF07731.9 KXX76282.1 - 3e-41 140.1 10.5 5.6e-36 123.0 1.6 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 KXX76282.1 - 1e-33 115.5 8.0 2e-30 104.9 0.3 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 KXX76282.1 - 1e-22 80.7 2.5 2.8e-22 79.3 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase PC4 PF02229.11 KXX76283.1 - 1.9e-20 71.8 0.1 3.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ApoB100_C PF12491.3 KXX76283.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal MFS_1 PF07690.11 KXX76285.1 - 8.2e-34 116.8 26.5 8.2e-34 116.8 18.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.3 KXX76285.1 - 0.98 8.0 4.1 1.5 7.3 2.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.13 KXX76286.1 - 5.7e-15 55.1 2.5 5.2e-13 48.6 1.7 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Gly_transf_sug PF04488.10 KXX76287.1 - 1.4e-10 41.4 0.0 3.5e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KXX76287.1 - 0.00055 18.5 0.0 0.00096 17.7 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain PBP PF01161.15 KXX76288.1 - 2.6e-10 40.2 0.1 3e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MGC-24 PF05283.6 KXX76289.1 - 0.037 13.8 12.1 0.048 13.4 8.4 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF566 PF04484.7 KXX76289.1 - 6 6.2 7.5 7.7 5.9 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Amnionless PF14828.1 KXX76290.1 - 0.16 10.4 0.0 0.28 9.6 0.0 1.4 1 0 0 1 1 1 0 Amnionless Gram_pos_anchor PF00746.16 KXX76290.1 - 9.7 6.1 11.0 1.9 8.3 2.7 2.5 2 0 0 2 2 2 0 Gram positive anchor Cation_efflux PF01545.16 KXX76291.1 - 5.9e-18 64.9 10.4 2.1e-17 63.1 7.2 1.7 1 1 0 1 1 1 1 Cation efflux family WD40 PF00400.27 KXX76293.1 - 4.2e-32 108.8 2.5 6.4e-12 44.8 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 KXX76293.1 - 0.00022 20.7 0.0 3.6 7.3 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 KXX76293.1 - 0.00057 19.3 0.1 0.47 9.8 0.0 2.2 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KXX76293.1 - 0.0021 16.2 0.0 0.98 7.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DPPIV_N PF00930.16 KXX76293.1 - 0.039 12.5 0.5 11 4.5 0.0 3.0 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PXA PF02194.10 KXX76294.1 - 2.9e-36 124.7 0.0 2.9e-36 124.7 0.0 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KXX76294.1 - 3.7e-21 75.3 1.5 6.1e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KXX76294.1 - 2.2e-07 30.6 0.0 7e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 PX domain DUF1886 PF09171.5 KXX76295.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) DUF3849 PF12960.2 KXX76295.1 - 0.14 12.1 0.5 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) NB-ARC PF00931.17 KXX76298.1 - 2.2e-14 53.0 0.0 3.5e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KXX76298.1 - 0.024 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 KXX76299.1 - 4.8e-26 90.5 25.6 2.1e-09 37.1 1.3 3.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KXX76299.1 - 2.4e-16 59.1 9.6 6.9e-06 25.6 0.2 4.1 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KXX76299.1 - 3.9e-15 54.7 8.9 2.4e-05 23.7 0.1 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KXX76299.1 - 4.1e-13 48.1 14.9 0.0012 18.5 0.2 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX76299.1 - 8.2e-11 40.8 3.1 0.058 13.2 0.1 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76299.1 - 2.3e-10 40.8 3.3 2e-05 25.1 0.2 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76299.1 - 4.4e-10 39.2 12.5 0.00037 20.8 0.1 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76299.1 - 8.2e-10 37.7 11.8 0.024 14.4 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 KXX76299.1 - 2e-08 33.8 8.5 0.18 12.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KXX76299.1 - 4.8e-08 32.6 14.0 0.013 15.4 0.3 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76299.1 - 5.5e-08 33.0 10.2 0.00056 20.1 0.2 4.5 1 1 4 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KXX76299.1 - 1.8e-07 31.2 3.5 0.0052 16.8 0.1 3.8 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KXX76299.1 - 1.3e-05 24.9 3.8 12 6.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 KXX76299.1 - 1.5e-05 24.3 0.2 3.7e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF3856 PF12968.2 KXX76299.1 - 0.00016 21.5 2.2 0.0024 17.6 0.2 2.7 2 2 0 2 2 2 1 Domain of Unknown Function (DUF3856) PPR PF01535.15 KXX76299.1 - 0.0019 18.0 0.1 10 6.3 0.0 3.9 4 0 0 4 4 3 0 PPR repeat RPN7 PF10602.4 KXX76299.1 - 0.0027 17.0 4.0 0.62 9.4 0.2 3.4 1 1 2 3 3 3 2 26S proteasome subunit RPN7 TPR_20 PF14561.1 KXX76299.1 - 0.0084 16.2 3.2 0.34 11.0 0.0 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX76299.1 - 0.028 14.8 8.4 2.6 8.6 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 KXX76299.1 - 0.042 13.3 0.0 8.7 5.9 0.0 3.4 3 0 0 3 3 3 0 PPR repeat MIT PF04212.13 KXX76299.1 - 0.088 12.6 4.4 5.4 6.9 0.1 3.5 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 KXX76299.1 - 0.093 12.7 1.2 0.2 11.6 0.2 2.0 2 0 0 2 2 2 0 Tetratrico peptide repeat BTAD PF03704.12 KXX76299.1 - 0.15 12.3 4.8 8.5 6.6 0.9 3.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Pkinase PF00069.20 KXX76300.1 - 1.4e-18 66.9 0.0 8.7e-18 64.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76300.1 - 7.2e-07 28.5 0.1 0.069 12.2 0.1 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KXX76300.1 - 0.058 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Sec63 PF02889.11 KXX76301.1 - 2.4e-40 138.7 0.0 4.4e-40 137.8 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KXX76301.1 - 3.7e-27 94.8 0.0 2.3e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX76301.1 - 1.8e-10 40.5 0.0 2.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX76301.1 - 1.4e-08 34.7 0.0 3.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 KXX76301.1 - 2.5e-05 24.3 0.0 9.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 KXX76301.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX76301.1 - 0.032 13.9 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KXX76301.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Spore_YunB PF09560.5 KXX76301.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) UvrD-helicase PF00580.16 KXX76301.1 - 0.067 12.4 0.0 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KXX76301.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase MFS_1 PF07690.11 KXX76302.1 - 1e-26 93.5 30.7 1e-26 93.5 21.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 KXX76303.1 - 1.4e-17 64.3 0.0 3.7e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Exo_endo_phos PF03372.18 KXX76304.1 - 1e-11 45.2 0.1 1.6e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KXX76304.1 - 0.088 12.4 0.4 0.7 9.5 0.3 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Methyltransf_23 PF13489.1 KXX76305.1 - 1.6e-20 73.4 0.0 2.1e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76305.1 - 1.6e-15 57.3 0.0 4.9e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76305.1 - 1.8e-13 51.0 0.0 3.7e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76305.1 - 1.9e-13 50.2 0.0 2.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX76305.1 - 4.7e-13 49.4 0.0 9.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX76305.1 - 5.9e-09 36.2 0.0 1.4e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX76305.1 - 1.8e-07 31.2 0.2 6.6e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX76305.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.6 KXX76305.1 - 0.00017 20.4 0.0 0.0002 20.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DUF938 PF06080.7 KXX76305.1 - 0.00038 20.0 0.0 0.0005 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.15 KXX76305.1 - 0.00086 18.3 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KXX76305.1 - 0.004 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KXX76305.1 - 0.012 14.4 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Methyltransf_24 PF13578.1 KXX76305.1 - 0.028 15.2 0.0 0.05 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KXX76305.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.14 KXX76305.1 - 0.036 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.2 KXX76305.1 - 0.057 13.0 0.0 0.67 9.6 0.0 2.2 1 1 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase CMAS PF02353.15 KXX76305.1 - 0.058 12.4 0.0 0.15 11.0 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.12 KXX76305.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin N6_N4_Mtase PF01555.13 KXX76305.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 2 0 0 2 2 1 0 DNA methylase Methyltransf_16 PF10294.4 KXX76305.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Terpene_synth_C PF03936.11 KXX76308.1 - 3.4e-05 23.2 0.0 7.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 KXX76308.1 - 0.0024 17.7 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KXX76308.1 - 0.0032 16.9 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX76308.1 - 0.019 13.9 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.17 KXX76309.1 - 9.1e-59 199.1 0.0 1.1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 KXX76310.1 - 1.2e-07 31.8 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX76310.1 - 5.5e-07 29.4 0.0 9.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX76310.1 - 7.2e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX76310.1 - 1.8e-05 25.1 0.1 5e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX76310.1 - 0.076 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_3 PF13302.1 KXX76311.1 - 5.2e-34 117.4 0.0 6.7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX76311.1 - 0.0041 17.1 0.0 0.044 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family GFO_IDH_MocA PF01408.17 KXX76312.1 - 4.7e-17 62.6 0.2 1.5e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KXX76312.1 - 3.1e-05 23.7 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 KXX76312.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KXX76312.1 - 0.097 12.9 0.2 0.38 11.0 0.0 2.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DAO PF01266.19 KXX76313.1 - 1.8e-17 63.2 1.1 2.2e-17 63.0 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase tRNA-synt_1 PF00133.17 KXX76314.1 - 2.1e-206 686.5 0.0 1.3e-205 683.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KXX76314.1 - 1.5e-26 92.9 0.3 1.5e-26 92.9 0.2 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 KXX76314.1 - 4.4e-12 45.6 0.0 1.4e-07 31.0 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KXX76314.1 - 5.4e-12 45.0 0.6 6e-05 21.8 0.1 4.4 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KXX76314.1 - 0.018 14.1 0.0 0.3 10.1 0.0 2.7 2 1 1 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF4028 PF13220.1 KXX76314.1 - 0.028 14.0 0.8 0.084 12.5 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Coq4 PF05019.8 KXX76316.1 - 0.039 12.8 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 p450 PF00067.17 KXX76317.1 - 1.7e-06 26.8 0.0 2.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 KXX76318.1 - 3.9e-08 32.6 5.0 1.8e-07 30.5 3.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SpoVIF PF14069.1 KXX76318.1 - 0.095 12.4 0.1 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Stage VI sporulation protein F SH3_3 PF08239.6 KXX76319.1 - 1.3e-06 28.5 0.3 2.4e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.8 KXX76319.1 - 0.03 13.8 0.0 0.17 11.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial SH3 domain CorA PF01544.13 KXX76320.1 - 0.055 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Dioxygenase_C PF00775.16 KXX76321.1 - 5.8e-11 41.9 4.5 8.8e-10 38.1 3.1 2.3 1 1 0 1 1 1 1 Dioxygenase 5-FTHF_cyc-lig PF01812.15 KXX76322.1 - 4.2e-28 98.3 0.0 5e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PLDc_2 PF13091.1 KXX76323.1 - 9.5e-14 51.2 0.0 5.7e-06 26.0 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 KXX76323.1 - 6e-12 44.9 0.4 0.00015 21.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif FR47 PF08445.5 KXX76324.1 - 4.4e-09 35.9 0.0 7.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KXX76324.1 - 3.8e-08 33.2 0.1 5.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX76324.1 - 1.9e-06 27.9 0.1 2.6e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX76324.1 - 0.0007 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX76324.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec62 PF03839.11 KXX76326.1 - 1.7e-52 178.0 0.2 1.7e-52 178.0 0.1 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 SelP_N PF04592.9 KXX76326.1 - 0.7 9.2 7.4 1.2 8.4 5.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KXX76326.1 - 0.83 8.5 2.9 2.1 7.3 1.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KXX76326.1 - 9.9 4.8 21.7 14 4.3 15.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 KXX76327.1 - 1.6e-35 122.4 22.6 2.4e-27 95.6 2.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX76327.1 - 4.6e-11 41.9 1.5 4.6e-11 41.9 1.0 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KXX76327.1 - 0.00083 17.8 4.5 0.00083 17.8 3.1 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein Inositol_P PF00459.20 KXX76328.1 - 6e-60 202.8 0.0 6.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1134 PF06577.7 KXX76328.1 - 0.079 12.4 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) LSM PF01423.17 KXX76329.1 - 1.6e-16 59.5 0.5 2e-16 59.2 0.4 1.1 1 0 0 1 1 1 1 LSM domain Thioredoxin PF00085.15 KXX76330.1 - 3e-39 132.8 0.0 2.4e-25 88.2 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KXX76330.1 - 7.4e-13 48.7 0.0 0.00087 19.1 0.0 3.9 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KXX76330.1 - 7.1e-09 35.8 0.2 0.0012 19.0 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX76330.1 - 3.2e-07 30.3 0.9 0.00052 20.0 0.0 4.3 5 1 0 5 5 5 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KXX76330.1 - 2.8e-05 24.0 0.9 0.00015 21.7 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KXX76330.1 - 0.0086 15.9 0.0 3.3 7.6 0.0 3.0 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KXX76330.1 - 0.023 14.3 2.1 2 8.0 0.1 3.8 3 1 1 4 4 4 0 AhpC/TSA family Thioredoxin_3 PF13192.1 KXX76330.1 - 0.13 12.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Tyr-DNA_phospho PF06087.7 KXX76331.1 - 5.1e-131 437.3 0.0 6.4e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KXX76331.1 - 0.032 13.9 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain PepSY_TM PF03929.11 KXX76332.1 - 3.8 8.0 5.6 6.5 7.3 3.9 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix His_Phos_2 PF00328.17 KXX76333.1 - 1e-52 179.6 0.0 1.2e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OPT PF03169.10 KXX76334.1 - 2e-207 690.4 35.0 2.4e-207 690.2 24.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ACBP PF00887.14 KXX76335.1 - 2.1e-23 81.8 1.0 2.4e-23 81.6 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein GRAM PF02893.15 KXX76336.1 - 7.8e-17 60.5 0.0 1.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.7 KXX76336.1 - 0.65 9.1 2.4 0.35 10.0 0.1 1.7 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 KXX76336.1 - 1.2 8.6 8.1 2.7 7.4 5.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Atg14 PF10186.4 KXX76337.1 - 0.01 14.8 1.9 0.016 14.1 1.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIVA PF05103.8 KXX76337.1 - 0.03 14.3 1.0 0.03 14.3 0.7 2.6 3 0 0 3 3 3 0 DivIVA protein DUF4611 PF15387.1 KXX76337.1 - 0.13 12.3 2.5 2.3 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF972 PF06156.8 KXX76337.1 - 0.24 11.7 9.7 0.88 9.9 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Matrilin_ccoil PF10393.4 KXX76337.1 - 0.45 9.9 2.0 19 4.6 0.0 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TBPIP PF07106.8 KXX76337.1 - 0.51 9.8 5.5 6.3 6.3 0.2 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 PF14362.1 KXX76337.1 - 0.71 8.7 7.2 0.093 11.6 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.1 KXX76337.1 - 1.5 8.2 12.8 2.3 7.6 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 KXX76337.1 - 3 7.7 11.1 0.67 9.7 2.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 KXX76337.1 - 3.7 7.5 20.0 0.16 11.9 5.5 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Rootletin PF15035.1 KXX76337.1 - 6.2 6.7 18.4 2.9 7.8 0.6 2.7 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Ax_dynein_light PF10211.4 KXX76337.1 - 7.6 6.3 10.7 2.7 7.8 4.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain End3 PF12761.2 KXX76339.1 - 4.6e-74 248.3 2.7 6.3e-74 247.8 1.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KXX76339.1 - 5.8e-49 164.1 0.0 2e-48 162.4 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KXX76339.1 - 9.9e-07 27.6 0.2 2.1e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KXX76339.1 - 5.2e-06 25.9 0.1 1.2e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KXX76339.1 - 1.2e-05 25.3 0.0 7.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KXX76339.1 - 0.0013 18.4 0.3 0.0051 16.5 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KXX76339.1 - 0.0058 15.9 0.2 0.017 14.4 0.1 1.8 1 0 0 1 1 1 1 EF hand Mnd1 PF03962.10 KXX76339.1 - 0.047 13.3 6.1 0.16 11.5 4.3 1.9 1 1 0 1 1 1 0 Mnd1 family DUF641 PF04859.7 KXX76339.1 - 0.062 13.0 3.6 0.099 12.4 1.4 2.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Vfa1 PF08432.5 KXX76339.1 - 0.52 10.3 3.2 1.8 8.5 2.2 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Lge1 PF11488.3 KXX76339.1 - 2 8.6 4.5 9.7 6.4 3.1 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 COG2 PF06148.6 KXX76339.1 - 2.2 8.1 6.6 1.3 8.9 0.4 3.1 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KXX76339.1 - 3.6 7.1 14.3 24 4.4 8.4 2.5 2 1 0 2 2 2 0 IncA protein MerR-DNA-bind PF09278.6 KXX76339.1 - 5.1 7.5 9.5 3.7 8.0 0.0 3.3 3 0 0 3 3 3 0 MerR, DNA binding Pyr_redox_2 PF07992.9 KXX76340.1 - 7.9e-20 71.5 0.2 1.3e-19 70.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX76340.1 - 5.5e-11 42.7 1.4 1.8e-07 31.4 0.7 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX76340.1 - 6e-06 26.4 0.7 0.014 15.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX76340.1 - 2.3e-05 23.4 0.0 0.0036 16.2 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KXX76340.1 - 0.0051 16.5 0.1 2.9 7.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding TMF_TATA_bd PF12325.3 KXX76341.1 - 0.04 13.6 0.3 0.066 12.9 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YvrJ PF12841.2 KXX76341.1 - 0.09 12.0 0.0 5.8 6.2 0.0 2.6 2 0 0 2 2 2 0 YvrJ protein family FadA PF09403.5 KXX76341.1 - 0.09 12.7 0.2 0.71 9.8 0.1 2.0 1 1 1 2 2 2 0 Adhesion protein FadA ADH_zinc_N PF00107.21 KXX76343.1 - 7e-25 87.0 0.1 1.2e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX76343.1 - 9.6e-11 42.6 0.0 2.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KXX76343.1 - 0.016 14.7 0.1 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Vma12 PF11712.3 KXX76344.1 - 1.6e-37 128.3 0.0 2.9e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PSDC PF12588.3 KXX76344.1 - 8.6e-29 99.9 0.0 1.7e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Claudin_2 PF13903.1 KXX76344.1 - 0.026 14.2 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2200 PF09966.4 KXX76344.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) SYS1 PF09801.4 KXX76345.1 - 9.6e-50 168.3 3.7 1.1e-49 168.0 2.6 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.9 KXX76345.1 - 0.034 13.8 0.5 0.059 13.0 0.3 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF412 PF04217.8 KXX76345.1 - 4 7.2 6.0 0.33 10.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF412 PIP5K PF01504.13 KXX76346.1 - 2.2e-87 292.3 0.1 3.3e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Amidohydro_1 PF01979.15 KXX76347.1 - 2.8e-19 69.9 1.0 2.8e-11 43.6 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KXX76347.1 - 5.2e-14 52.9 0.2 7.5e-12 45.8 0.2 3.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KXX76347.1 - 1.8e-09 37.2 0.0 4.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX76347.1 - 2.2e-08 33.7 0.2 5.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family XPG_I PF00867.13 KXX76348.1 - 1.8e-30 104.8 0.7 3.5e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KXX76348.1 - 4.1e-25 87.9 0.0 4.1e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KXX76348.1 - 1e-05 25.6 0.2 9.3e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 KXX76348.1 - 0.054 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein NAD_binding_6 PF08030.7 KXX76349.1 - 4.7e-31 107.8 0.0 9.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KXX76349.1 - 3.2e-20 71.9 0.0 9.8e-20 70.3 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KXX76349.1 - 1e-16 61.1 18.9 3.8e-16 59.3 6.9 2.3 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KXX76349.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UQ_con PF00179.21 KXX76350.1 - 3.5e-52 175.5 0.0 4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX76350.1 - 0.00026 20.7 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX76350.1 - 0.0014 18.5 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KXX76350.1 - 0.01 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Arc_PepC PF06819.6 KXX76351.1 - 0.029 14.2 0.0 0.047 13.6 0.0 1.4 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Tim17 PF02466.14 KXX76353.1 - 1.1e-14 54.5 4.7 1.8e-14 53.9 3.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family YjgP_YjgQ PF03739.9 KXX76353.1 - 0.21 10.2 0.6 0.35 9.5 0.4 1.3 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family UCH PF00443.24 KXX76354.1 - 3.5e-27 95.2 0.0 1.1e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX76354.1 - 2.6e-09 36.9 0.4 0.00045 19.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KXX76354.1 - 8.8e-09 34.6 0.0 0.011 15.1 0.0 3.6 3 0 0 3 3 3 3 A repeated domain in UCH-protein PUB PF09409.5 KXX76354.1 - 0.00044 19.9 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 PUB domain TPR_10 PF13374.1 KXX76355.1 - 4.8e-31 105.7 4.7 4.4e-10 39.1 0.0 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76355.1 - 6.2e-23 80.5 1.7 3.3e-12 46.1 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX76355.1 - 3.2e-09 36.0 0.0 6.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.9 KXX76355.1 - 3.6e-07 29.9 1.0 0.19 12.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX76355.1 - 2.9e-06 26.7 1.3 4.4 7.4 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76355.1 - 3.8e-06 26.2 0.3 2.1 8.3 0.0 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76355.1 - 2.9e-05 24.5 0.0 0.26 12.0 0.0 3.6 1 1 1 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.7 KXX76355.1 - 8.6e-05 22.2 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 KXX76355.1 - 0.00045 19.8 0.0 0.13 11.9 0.0 3.0 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.1 KXX76355.1 - 0.00047 20.5 4.8 4.2 8.2 0.0 5.7 3 1 2 5 5 5 1 Tetratricopeptide repeat AAA_25 PF13481.1 KXX76355.1 - 0.0042 16.5 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX76355.1 - 0.0086 16.0 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX76355.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.1 KXX76355.1 - 0.029 14.5 0.0 22 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76355.1 - 0.038 14.3 1.8 14 6.1 0.0 4.1 3 2 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KXX76355.1 - 0.046 13.7 0.2 25 5.1 0.0 3.1 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.1 KXX76355.1 - 0.14 12.5 0.4 51 4.5 0.0 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 KXX76355.1 - 0.23 11.9 1.2 1.5e+02 3.1 0.0 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.19 KXX76356.1 - 3.9e-41 140.6 0.2 5.5e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX76356.1 - 5.3e-21 73.8 0.2 1.1e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KXX76356.1 - 1.6e-20 72.6 0.4 3e-20 71.7 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KXX76356.1 - 8.4e-17 61.7 0.0 2e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX76356.1 - 8.4e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 KXX76356.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP MutS_V PF00488.16 KXX76357.1 - 7e-98 326.7 0.0 1.1e-97 326.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KXX76357.1 - 7.6e-40 136.8 1.2 1.9e-39 135.5 0.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KXX76357.1 - 1.2e-20 73.9 0.2 6.7e-20 71.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KXX76357.1 - 3.1e-18 65.7 0.5 3.1e-18 65.7 0.3 3.1 4 0 0 4 4 4 1 MutS family domain IV AAA_22 PF13401.1 KXX76357.1 - 0.075 13.1 0.1 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain COX6B PF02297.12 KXX76358.1 - 2.3e-23 82.0 5.2 2.8e-23 81.7 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KXX76358.1 - 0.0084 16.1 0.7 0.015 15.2 0.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 polyprenyl_synt PF00348.12 KXX76359.1 - 6.3e-54 182.5 0.1 5.1e-50 169.7 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KXX76359.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TPR_10 PF13374.1 KXX76361.1 - 2.1e-76 249.9 3.2 1.2e-13 50.4 0.1 7.3 8 0 0 8 8 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76361.1 - 2.2e-64 213.3 8.8 1.3e-21 76.3 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX76361.1 - 3.2e-30 103.5 25.2 7.6e-09 35.1 0.2 5.2 3 1 4 7 7 7 5 TPR repeat TPR_7 PF13176.1 KXX76361.1 - 6.9e-30 100.4 11.9 0.00012 21.6 0.1 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 KXX76361.1 - 2.1e-27 93.5 17.9 0.00034 20.1 0.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KXX76361.1 - 5.4e-21 72.7 11.6 0.0024 17.6 0.2 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KXX76361.1 - 8.7e-21 72.3 5.3 0.036 14.2 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76361.1 - 2.6e-16 59.8 0.2 0.00047 20.7 0.0 4.7 1 1 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KXX76361.1 - 1.3e-14 54.0 3.2 0.00027 20.9 0.1 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KXX76361.1 - 1.4e-12 47.7 13.9 0.0021 18.3 2.3 6.2 2 1 4 6 6 6 5 Tetratricopeptide repeat NB-ARC PF00931.17 KXX76361.1 - 9.6e-11 41.0 0.1 2.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_15 PF13429.1 KXX76361.1 - 8.1e-08 31.6 1.1 0.068 12.2 0.0 5.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76361.1 - 2.2e-07 30.8 11.5 1.1 10.0 0.1 8.1 5 1 3 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 KXX76361.1 - 8.1e-07 28.8 0.0 9.3 7.0 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KXX76361.1 - 2e-06 27.1 20.3 0.26 11.1 0.1 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat AAA_16 PF13191.1 KXX76361.1 - 2.7e-05 24.2 0.6 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain PPR PF01535.15 KXX76361.1 - 4.9e-05 23.0 0.2 57 4.0 0.0 6.2 6 0 0 6 6 5 0 PPR repeat DUF3366 PF11846.3 KXX76361.1 - 0.0026 17.6 5.5 1.2 9.0 0.6 4.5 1 1 4 5 5 5 1 Domain of unknown function (DUF3366) TPR_6 PF13174.1 KXX76361.1 - 0.0071 16.7 9.6 19 5.9 0.0 7.8 8 2 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 KXX76361.1 - 0.0087 16.1 3.9 1e+02 3.1 0.1 5.9 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF676 PF05057.9 KXX76361.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF627 PF04781.7 KXX76361.1 - 0.011 15.3 10.6 13 5.4 0.1 5.9 2 1 5 7 7 6 0 Protein of unknown function (DUF627) Abhydrolase_6 PF12697.2 KXX76361.1 - 0.019 14.8 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Tcf25 PF04910.9 KXX76361.1 - 0.024 13.6 2.7 3.4 6.5 0.0 3.5 1 1 2 4 4 4 0 Transcriptional repressor TCF25 FTCD PF02971.9 KXX76361.1 - 0.026 14.1 0.5 71 3.0 0.0 4.8 3 1 3 6 6 6 0 Formiminotransferase domain Rab5-bind PF09311.6 KXX76361.1 - 0.028 14.3 19.0 0.37 10.6 0.9 4.2 1 1 3 4 4 4 0 Rabaptin-like protein Ribosomal_S7 PF00177.16 KXX76361.1 - 0.047 13.2 7.5 3 7.4 0.1 4.8 1 1 4 5 5 5 0 Ribosomal protein S7p/S5e YjgF_endoribonc PF14588.1 KXX76361.1 - 0.058 13.3 0.2 22 4.9 0.0 3.5 2 1 1 3 3 3 0 YjgF/chorismate_mutase-like, putative endoribonuclease PGAP1 PF07819.8 KXX76361.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF1925 PF09094.6 KXX76361.1 - 0.1 12.5 12.0 23 5.0 0.1 5.8 2 1 5 7 7 6 0 Domain of unknown function (DUF1925) TPR_3 PF07720.7 KXX76361.1 - 0.15 11.8 14.9 1.1 9.1 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat PS_Dcarbxylase PF02666.10 KXX76362.1 - 4.7e-23 81.5 0.0 6.2e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 KXX76362.1 - 0.064 12.9 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Acyl-CoA_dh_1 PF00441.19 KXX76363.1 - 4.5e-24 85.2 0.3 8.2e-24 84.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX76363.1 - 1.6e-23 83.3 0.1 3.9e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KXX76363.1 - 2.4e-18 65.3 0.0 6.8e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KXX76363.1 - 5.6e-08 33.1 0.3 1.1e-07 32.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_methylase PF00145.12 KXX76365.1 - 4.3e-34 118.1 0.0 9.3e-26 90.7 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 KXX76365.1 - 4e-07 29.7 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 KXX76365.1 - 0.18 11.4 0.5 0.33 10.6 0.4 1.3 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain zf-RING_2 PF13639.1 KXX76366.1 - 6.4e-08 32.3 11.7 1.1e-07 31.5 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX76366.1 - 1.4e-07 31.3 8.0 2.5e-07 30.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX76366.1 - 1.7e-06 27.5 7.0 2.7e-06 26.9 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX76366.1 - 2.6e-05 23.7 7.5 4e-05 23.2 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX76366.1 - 0.00019 21.4 9.7 0.0005 20.1 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger GAGA PF09237.6 KXX76366.1 - 0.093 12.3 0.0 0.093 12.3 0.0 3.2 3 0 0 3 3 3 0 GAGA factor zf-Apc11 PF12861.2 KXX76366.1 - 0.2 11.5 3.0 0.46 10.3 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KXX76366.1 - 1.1 8.8 5.9 2 8.0 4.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KXX76366.1 - 2 8.1 8.8 3.5 7.4 6.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-MIZ PF02891.15 KXX76366.1 - 3.7 7.1 9.0 6.4 6.3 6.2 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Drc1-Sld2 PF11719.3 KXX76367.1 - 2.8e-85 286.9 23.0 9.7e-85 285.2 16.0 1.7 1 1 0 1 1 1 1 DNA replication and checkpoint protein Upf2 PF04050.9 KXX76367.1 - 0.017 14.8 1.3 0.017 14.8 0.9 3.3 4 0 0 4 4 4 0 Up-frameshift suppressor 2 TFIID_20kDa PF03847.8 KXX76368.1 - 3.8e-18 65.5 0.0 6.8e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Rpn3_C PF08375.6 KXX76369.1 - 1.1e-24 86.5 1.4 2.9e-24 85.2 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KXX76369.1 - 3.6e-20 72.2 1.2 2.2e-19 69.7 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KXX76369.1 - 0.015 15.1 0.1 0.048 13.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 KXX76370.1 - 8.7e-08 32.0 8.2 0.0008 19.6 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KXX76370.1 - 1.5e-07 30.5 0.0 0.00012 21.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KXX76370.1 - 8.4e-05 22.6 2.1 8.4e-05 22.6 1.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX76370.1 - 3.8 7.9 6.6 4.9 7.6 2.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain FTHFS PF01268.14 KXX76371.1 - 1.1e-258 858.8 0.1 1.4e-258 858.4 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KXX76371.1 - 7.6e-68 226.6 0.7 7.6e-68 226.6 0.5 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KXX76371.1 - 8.5e-39 132.2 0.2 1.8e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.10 KXX76371.1 - 0.11 12.1 0.0 8.8 6.0 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region GTP_EFTU PF00009.22 KXX76371.1 - 0.13 11.6 0.7 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 KXX76372.1 - 6.2e-32 108.3 0.7 5.3e-12 45.1 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KXX76372.1 - 2.5e-05 22.6 0.1 3.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX76372.1 - 0.0013 17.6 0.0 0.0085 14.8 0.0 2.0 1 1 0 1 1 1 1 Nup133 N terminal like eIF2A PF08662.6 KXX76372.1 - 0.0015 18.2 0.2 1 9.0 0.0 3.2 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KXX76372.1 - 0.0023 16.7 0.1 0.64 8.7 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region DSBA PF01323.15 KXX76373.1 - 9.6e-41 139.4 0.0 1.1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KXX76373.1 - 1.1e-05 25.4 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KXX76373.1 - 0.00079 19.1 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_2 PF13098.1 KXX76373.1 - 0.046 13.9 0.0 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain Fig1 PF12351.3 KXX76374.1 - 1.9e-57 194.0 3.0 2.4e-57 193.8 2.1 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KXX76374.1 - 1.2e-07 31.5 2.6 1.5e-07 31.1 1.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KXX76374.1 - 2.2e-05 23.5 5.4 2.9e-05 23.1 3.7 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.1 KXX76374.1 - 0.59 9.5 6.2 0.092 12.1 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.1 KXX76374.1 - 2.4 8.3 12.4 0.15 12.1 0.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.10 KXX76374.1 - 2.8 8.2 9.1 0.38 11.0 0.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2976 PF11190.3 KXX76374.1 - 4.4 6.8 10.8 4.5 6.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Glyco_hydro_47 PF01532.15 KXX76376.1 - 5.1e-49 167.1 0.2 5.1e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APP_E2 PF12925.2 KXX76376.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein Glyco_hydro_47 PF01532.15 KXX76377.1 - 3.1e-118 395.3 0.0 3.9e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4588 PF15251.1 KXX76378.1 - 7.5e-08 32.6 0.4 9.8e-08 32.2 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 KXX76379.1 - 2.5e-82 276.0 0.1 4e-82 275.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KXX76379.1 - 5.2e-46 155.2 2.4 1.5e-45 153.7 1.7 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KXX76379.1 - 3.6e-38 130.4 3.4 3.6e-38 130.4 2.4 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KXX76379.1 - 3.4e-15 55.6 0.0 1.5e-14 53.5 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KXX76379.1 - 8e-09 34.7 0.0 1.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KXX76379.1 - 4.7e-08 33.0 0.0 3.8e-07 30.1 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KXX76379.1 - 9.9e-05 21.8 0.0 0.00027 20.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 KXX76379.1 - 0.02 14.8 0.3 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 KXX76379.1 - 0.037 13.4 0.2 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 Pkinase PF00069.20 KXX76381.1 - 3.5e-66 223.0 0.0 5.1e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76381.1 - 2.8e-49 167.5 0.0 4.5e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX76381.1 - 1.8e-09 37.0 0.0 2.5e-07 29.9 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 KXX76381.1 - 0.0069 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX76381.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DASH_Spc34 PF08657.5 KXX76382.1 - 1.5e-55 188.6 0.4 1.8e-54 185.1 0.3 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 DUF4407 PF14362.1 KXX76382.1 - 0.059 12.3 1.4 0.068 12.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 KXX76382.1 - 0.12 12.3 1.9 0.17 11.9 1.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4193 PF13834.1 KXX76382.1 - 0.16 12.1 2.3 0.28 11.3 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) V-SNARE PF05008.10 KXX76382.1 - 0.23 11.6 4.7 1.8 8.7 0.5 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4140 PF13600.1 KXX76382.1 - 3.6 8.0 6.2 1.5 9.3 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.27 KXX76384.1 - 1e-12 47.4 10.9 9e-05 22.2 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_S14 PF00253.16 KXX76385.1 - 1.6e-17 62.6 0.5 3.1e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Radical_SAM PF04055.16 KXX76386.1 - 1.2e-14 54.8 0.0 1.8e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TPR_10 PF13374.1 KXX76387.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat RCC1 PF00415.13 KXX76389.1 - 3.9e-61 203.0 3.1 5.9e-14 52.0 0.0 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KXX76389.1 - 3.4e-36 122.0 21.5 1.4e-09 37.2 0.6 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat QRPTase_C PF01729.14 KXX76390.1 - 3.3e-53 179.6 0.0 4e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KXX76390.1 - 3.8e-23 81.1 0.0 8.6e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Synaptobrevin PF00957.16 KXX76391.1 - 1.5e-32 111.0 0.5 1.9e-32 110.7 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 KXX76391.1 - 0.089 11.3 0.3 0.11 11.0 0.2 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF619 PF04768.8 KXX76392.1 - 3.7e-50 169.6 0.1 6.5e-50 168.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KXX76392.1 - 3.1e-30 104.9 0.0 9.8e-30 103.3 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KXX76392.1 - 5.8e-29 101.3 0.0 9.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KXX76392.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dhC PF02774.13 KXX76393.1 - 1.1e-40 139.4 0.0 1.6e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KXX76393.1 - 1.8e-14 54.0 0.0 7.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 KXX76395.1 - 9.5e-22 77.3 0.0 2.5e-21 76.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76395.1 - 3.5e-10 39.3 0.3 0.00025 20.1 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KXX76395.1 - 0.0063 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX76395.1 - 0.069 12.2 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.22 KXX76396.1 - 1.9e-49 167.1 0.1 6.6e-49 165.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KXX76396.1 - 1.4e-17 63.6 0.5 3.9e-17 62.2 0.3 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RRM_1 PF00076.17 KXX76397.1 - 6.4e-20 70.5 0.0 1.3e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX76397.1 - 1.3e-12 47.4 0.0 3e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX76397.1 - 0.048 13.5 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KXX76398.1 - 5.5e-05 22.9 11.1 9.5e-05 22.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTC PF01137.16 KXX76399.1 - 2.7e-37 127.7 0.0 3.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase ThiF PF00899.16 KXX76401.1 - 6.2e-35 119.9 0.0 1.2e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KXX76401.1 - 0.059 12.3 0.8 1.5 7.7 0.7 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 KXX76401.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 NAD_binding_7 PF13241.1 KXX76401.1 - 0.075 13.2 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 KXX76401.1 - 0.13 12.2 1.2 0.35 10.8 0.0 2.3 3 0 0 3 3 3 0 TrkA-N domain CAP_N PF01213.14 KXX76402.1 - 0.03 13.6 5.7 0.059 12.6 3.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KXX76402.1 - 0.26 10.5 8.9 0.018 14.3 2.4 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF605 PF04652.11 KXX76402.1 - 0.28 10.5 1.8 0.34 10.2 1.2 1.1 1 0 0 1 1 1 0 Vta1 like Dscam_C PF12355.3 KXX76402.1 - 2 8.6 11.4 0.64 10.3 5.6 1.9 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal HTH_Tnp_Tc5 PF03221.11 KXX76403.1 - 2e-10 40.3 0.0 6.2e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KXX76403.1 - 6.5e-07 28.6 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 KXX76403.1 - 0.0026 17.4 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 MarR family MAP65_ASE1 PF03999.7 KXX76403.1 - 0.013 14.1 0.9 0.021 13.4 0.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HTH_Tnp_4 PF13613.1 KXX76403.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 KXX76403.1 - 0.065 12.9 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 KXX76403.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 KXX76403.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TGS PF02824.16 KXX76404.1 - 1.4e-21 76.0 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KXX76404.1 - 2.7e-18 65.9 0.0 8.8e-18 64.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX76404.1 - 5.1e-10 38.8 0.1 2.6e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KXX76404.1 - 1.5e-05 24.5 0.1 0.32 10.3 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KXX76404.1 - 4.7e-05 23.2 0.1 0.012 15.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KXX76404.1 - 0.0048 17.3 0.0 0.06 13.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KXX76404.1 - 0.0057 15.4 0.3 0.024 13.4 0.1 2.0 2 0 0 2 2 2 1 ArgK protein DUF211 PF02680.9 KXX76404.1 - 0.031 14.0 0.6 0.16 11.7 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 AIG1 PF04548.11 KXX76404.1 - 0.058 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 AIG1 family PXA PF02194.10 KXX76405.1 - 3.7e-43 147.2 1.0 5.4e-43 146.7 0.7 1.2 1 0 0 1 1 1 1 PXA domain Steroid_dh PF02544.11 KXX76406.1 - 2e-11 43.8 1.4 7.1e-11 42.0 0.9 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ATP-synt_DE_N PF02823.11 KXX76407.1 - 4.7e-20 71.1 0.1 7.1e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Ank_2 PF12796.2 KXX76408.1 - 1.8e-25 89.0 0.0 3.2e-17 62.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76408.1 - 8.3e-18 63.2 2.1 2.5e-06 27.0 0.4 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KXX76408.1 - 2.5e-16 59.3 4.9 4.2e-08 33.1 0.3 4.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX76408.1 - 1.4e-14 54.1 0.1 0.00018 21.8 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX76408.1 - 4.2e-13 48.1 0.0 0.0017 18.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat 2OG-FeII_Oxy_2 PF13532.1 KXX76409.1 - 8.5e-14 51.8 0.0 1.9e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KXX76409.1 - 1.7e-08 34.6 0.0 4.1e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KXX76409.1 - 0.026 15.0 0.0 0.098 13.1 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF2457 PF10446.4 KXX76410.1 - 2.1e-154 514.6 36.8 2.1e-154 514.6 25.5 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 KXX76410.1 - 5.9 4.6 23.5 9.5 3.9 16.3 1.3 1 0 0 1 1 1 0 Nop14-like family Arf PF00025.16 KXX76411.1 - 2.5e-66 222.2 0.0 2.8e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KXX76411.1 - 4.7e-11 42.0 0.2 2.3e-07 29.8 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KXX76411.1 - 8.4e-08 32.7 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KXX76411.1 - 2.3e-07 30.2 0.0 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KXX76411.1 - 3.2e-07 30.3 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KXX76411.1 - 4.3e-07 29.4 0.0 6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KXX76411.1 - 1.8e-05 23.9 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KXX76411.1 - 0.00032 20.1 0.0 0.013 14.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KXX76411.1 - 0.039 13.3 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KXX76411.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Esterase_phd PF10503.4 KXX76412.1 - 0.013 14.7 0.6 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Reductase_C PF14759.1 KXX76412.1 - 0.065 13.5 0.0 0.63 10.3 0.0 2.2 2 0 0 2 2 2 0 Reductase C-terminal DUF3336 PF11815.3 KXX76413.1 - 1.7e-52 176.8 1.7 2.9e-52 176.0 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KXX76413.1 - 1.1e-19 71.1 0.0 4.1e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4337 PF14235.1 KXX76413.1 - 2.9 7.7 5.9 0.21 11.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) zf-Mss51 PF13824.1 KXX76414.1 - 3.3e-27 94.0 7.9 7.4e-27 92.9 5.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KXX76414.1 - 0.011 15.5 2.9 0.011 15.5 2.0 1.9 2 0 0 2 2 2 0 MYND finger CPSF_A PF03178.10 KXX76415.1 - 2.6e-101 338.9 0.0 6.6e-101 337.5 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 KXX76415.1 - 2.4e-63 214.0 0.0 4.2e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term KorB_C PF06613.6 KXX76415.1 - 0.02 14.2 0.0 0.061 12.7 0.0 1.8 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain DUF1945 PF09178.5 KXX76415.1 - 0.028 14.3 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) WD40 PF00400.27 KXX76415.1 - 0.13 12.2 0.1 0.55 10.2 0.1 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat UBA_4 PF14555.1 KXX76416.1 - 0.0053 16.2 0.3 0.013 14.9 0.2 1.6 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4_2 PF13923.1 KXX76416.1 - 0.45 10.5 12.0 0.052 13.5 3.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX76416.1 - 1.6 8.6 10.5 4.4 7.2 7.3 1.8 1 0 0 1 1 1 0 Ring finger domain DUF605 PF04652.11 KXX76416.1 - 2.8 7.2 13.4 3.4 6.9 9.3 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KXX76416.1 - 3 5.9 9.9 3.3 5.8 6.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_5 PF14634.1 KXX76416.1 - 7.8 6.3 13.1 22 4.8 9.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain TPR_10 PF13374.1 KXX76417.1 - 6.7e-35 118.0 10.7 2.9e-11 42.9 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76417.1 - 9.7e-34 115.1 10.7 1.9e-20 72.5 1.3 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76417.1 - 6.9e-18 62.9 10.8 6.5e-06 25.5 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX76417.1 - 7.9e-17 60.0 12.9 2e-06 27.1 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX76417.1 - 1.8e-15 56.3 21.4 4.8e-09 35.7 2.4 3.3 2 1 2 4 4 3 3 TPR repeat TPR_2 PF07719.12 KXX76417.1 - 9e-13 47.0 14.1 0.00015 21.4 0.2 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_4 PF07721.9 KXX76417.1 - 3.1e-12 45.6 0.9 0.041 14.3 0.0 4.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX76417.1 - 1.6e-11 43.1 12.3 0.0019 17.8 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76417.1 - 9.6e-09 35.6 12.2 1.9e-06 28.3 2.5 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76417.1 - 1.6e-08 34.4 14.7 0.022 15.3 0.1 5.4 6 0 0 6 6 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX76417.1 - 3.2e-07 30.0 10.1 0.21 11.8 0.1 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat AAA_16 PF13191.1 KXX76417.1 - 3.4e-07 30.4 0.0 9.1e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KXX76417.1 - 1.9e-06 26.9 0.0 0.0027 16.6 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_19 PF14559.1 KXX76417.1 - 2.4e-05 24.6 7.1 0.0026 18.0 0.7 3.6 4 1 0 4 4 2 2 Tetratricopeptide repeat DUF676 PF05057.9 KXX76417.1 - 0.00012 21.4 0.0 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AA_kinase PF00696.23 KXX76417.1 - 0.0006 19.4 0.6 0.044 13.3 0.0 2.8 3 0 0 3 3 3 1 Amino acid kinase family Abhydrolase_6 PF12697.2 KXX76417.1 - 0.0017 18.2 1.2 0.0017 18.2 0.8 2.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family Apc3 PF12895.2 KXX76417.1 - 0.0018 18.3 2.1 0.0069 16.4 0.2 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Arch_ATPase PF01637.13 KXX76417.1 - 0.0028 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase PGAP1 PF07819.8 KXX76417.1 - 0.0079 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein PPR PF01535.15 KXX76417.1 - 0.014 15.3 3.2 29 4.9 0.0 4.6 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.1 KXX76417.1 - 0.022 15.2 15.1 0.84 10.2 0.4 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat ARA70 PF12489.3 KXX76417.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear coactivator YjeF_N PF03853.10 KXX76417.1 - 0.1 12.1 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF2225 PF09986.4 KXX76417.1 - 0.17 11.3 2.0 2.6 7.4 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 KXX76417.1 - 0.28 10.5 2.9 12 5.2 0.1 3.0 1 1 2 3 3 3 0 26S proteasome subunit RPN7 Ni_hydr_CYTB PF01292.15 KXX76419.1 - 0.19 11.0 7.0 0.29 10.4 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 ABC2_membrane_4 PF12730.2 KXX76419.1 - 0.51 9.4 16.9 0.76 8.8 11.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EI24 PF07264.6 KXX76419.1 - 4 6.7 17.6 1.1 8.6 6.3 2.1 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Carb_bind PF10645.4 KXX76420.1 - 3.2e-15 55.6 9.3 3.2e-15 55.6 6.5 2.2 2 0 0 2 2 2 1 Carbohydrate binding Acetyltransf_1 PF00583.19 KXX76421.1 - 6.7e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX76421.1 - 2.6e-06 27.5 0.2 6.1e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX76421.1 - 3.6e-05 23.8 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX76421.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX76421.1 - 0.034 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF1992 PF09350.5 KXX76422.1 - 3.2e-25 87.7 0.4 7.9e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) AMP-binding PF00501.23 KXX76423.1 - 8.4e-74 248.4 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX76423.1 - 5.5e-14 52.8 0.1 1.7e-13 51.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KXX76424.1 - 7.3e-40 136.7 27.7 1.9e-39 135.3 17.7 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Ank_4 PF13637.1 KXX76426.1 - 6.5e-14 52.0 0.0 2e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX76426.1 - 1.9e-12 46.2 0.3 6.8e-11 41.4 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeat Ank_2 PF12796.2 KXX76426.1 - 3.7e-12 46.4 0.0 7.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX76426.1 - 2.4e-10 39.6 0.0 4e-08 32.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KXX76426.1 - 8.2e-10 38.6 0.1 3.2e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.18 KXX76426.1 - 2e-06 27.7 0.2 6.6e-06 26.0 0.0 2.0 3 0 0 3 3 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX76426.1 - 2.7e-06 26.6 0.1 1e-05 24.7 0.0 2.0 3 0 0 3 3 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KXX76426.1 - 4.2e-06 26.6 2.6 0.013 15.2 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_33 PF13671.1 KXX76426.1 - 0.00021 21.2 0.2 0.0098 15.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AIG1 PF04548.11 KXX76426.1 - 0.00041 19.5 0.5 0.0014 17.7 0.0 2.1 3 0 0 3 3 3 1 AIG1 family IIGP PF05049.8 KXX76426.1 - 0.00066 18.6 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 KXX76426.1 - 0.0011 19.7 0.0 0.0025 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX76426.1 - 0.0015 18.7 0.1 0.0076 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KXX76426.1 - 0.0026 18.2 0.2 0.0085 16.5 0.0 2.0 2 1 0 2 2 1 1 Miro-like protein Septin PF00735.13 KXX76426.1 - 0.0051 15.8 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Septin ATP_bind_1 PF03029.12 KXX76426.1 - 0.0057 16.2 0.1 0.046 13.2 0.0 2.3 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KXX76426.1 - 0.0062 16.8 0.0 0.016 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 KXX76426.1 - 0.0082 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KXX76426.1 - 0.0099 15.3 0.0 0.048 13.1 0.0 2.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.12 KXX76426.1 - 0.011 15.5 2.2 0.031 14.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 WXG100 PF06013.7 KXX76426.1 - 0.016 15.1 0.9 0.082 12.9 0.9 2.0 2 0 0 2 2 1 0 Proteins of 100 residues with WXG AAA_23 PF13476.1 KXX76426.1 - 0.018 15.3 0.3 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KXX76426.1 - 0.02 14.3 0.2 0.11 11.9 0.0 2.3 2 1 1 3 3 2 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KXX76426.1 - 0.022 13.6 0.0 0.05 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KXX76426.1 - 0.025 14.8 0.9 0.15 12.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KXX76426.1 - 0.034 14.1 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 KXX76426.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Spore_IV_A PF09547.5 KXX76426.1 - 0.055 12.1 0.2 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) MobB PF03205.9 KXX76426.1 - 0.055 13.1 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KXX76426.1 - 0.063 12.9 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 1 0 Archaeal ATPase Zeta_toxin PF06414.7 KXX76426.1 - 0.084 11.9 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 KXX76426.1 - 0.1 12.0 0.0 0.69 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KXX76426.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KXX76426.1 - 0.16 11.3 0.2 1.2 8.5 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain DivIC PF04977.10 KXX76426.1 - 0.17 11.3 2.2 0.38 10.2 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.2 KXX76427.1 - 6.1e-46 154.6 9.6 1.3e-13 51.1 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76427.1 - 1.6e-38 128.6 16.8 3.2e-08 32.9 0.3 8.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 KXX76427.1 - 5e-36 119.1 7.5 2.7e-05 23.9 0.1 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KXX76427.1 - 6e-36 121.6 10.3 4.3e-07 29.9 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX76427.1 - 2.1e-31 107.7 3.9 9.9e-09 35.4 0.1 5.5 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KXX76427.1 - 0.083 12.3 0.1 8 5.8 0.0 3.0 3 0 0 3 3 3 0 Shigella flexneri OspC protein MMR_HSR1 PF01926.18 KXX76428.1 - 3e-07 30.3 0.0 1.1e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX76428.1 - 8.8e-07 28.2 0.0 2.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX76428.1 - 0.00014 21.9 0.2 0.0025 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 KXX76428.1 - 0.00025 20.8 1.8 0.11 12.3 0.0 2.9 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 KXX76428.1 - 0.00031 19.8 0.0 0.13 11.3 0.0 2.8 2 0 0 2 2 2 2 AIG1 family T2SE PF00437.15 KXX76428.1 - 0.0025 16.7 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KXX76428.1 - 0.0028 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KXX76428.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Septin PF00735.13 KXX76428.1 - 0.018 14.0 0.2 0.064 12.2 0.1 1.9 1 1 0 1 1 1 0 Septin IIGP PF05049.8 KXX76428.1 - 0.023 13.5 0.0 0.057 12.2 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KXX76428.1 - 0.073 13.3 0.2 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KXX76428.1 - 0.74 10.1 4.5 0.76 10.0 0.0 2.7 2 1 0 2 2 1 0 AAA domain TauD PF02668.11 KXX76429.1 - 1.1e-28 100.5 0.0 1.4e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX76429.1 - 0.00061 18.7 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.13 KXX76430.1 - 0.11 12.4 6.9 0.24 11.3 4.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX76431.1 - 3e-19 68.9 0.1 5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cons_hypoth698 PF03601.9 KXX76431.1 - 0.013 14.1 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 DUF3369 PF11849.3 KXX76431.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) F-box-like PF12937.2 KXX76433.1 - 0.006 16.2 1.5 0.013 15.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX76433.1 - 0.056 13.1 0.8 0.16 11.7 0.5 1.7 1 0 0 1 1 1 0 F-box domain Pkinase_Tyr PF07714.12 KXX76434.1 - 9.5e-07 28.1 0.0 2.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KXX76434.1 - 5.8e-06 25.6 0.0 2.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1996 PF09362.5 KXX76436.1 - 1.1e-89 300.1 1.4 1.3e-89 299.9 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.6 KXX76437.1 - 1.1e-05 25.5 0.1 0.00095 19.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MgsA_C PF12002.3 KXX76438.1 - 4.6e-61 205.3 0.0 1.5e-60 203.7 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KXX76438.1 - 1.1e-12 48.3 0.0 2.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX76438.1 - 1.2e-10 40.8 0.0 1.5e-09 37.2 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KXX76438.1 - 8.3e-07 28.6 0.1 3.3e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KXX76438.1 - 3.9e-05 23.7 0.9 0.00035 20.7 0.3 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KXX76438.1 - 0.00011 21.9 0.2 0.0087 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX76438.1 - 0.00011 21.8 0.1 0.00052 19.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KXX76438.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KXX76438.1 - 0.00037 19.7 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KXX76438.1 - 0.00051 20.0 5.7 0.0081 16.1 0.0 3.3 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KXX76438.1 - 0.00078 18.2 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KXX76438.1 - 0.0017 19.1 0.0 0.004 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KXX76438.1 - 0.0029 17.1 0.1 0.078 12.5 0.0 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KXX76438.1 - 0.0031 16.5 0.0 0.0069 15.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 KXX76438.1 - 0.017 14.9 0.2 3.8 7.3 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 KXX76438.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 KXX76438.1 - 0.081 12.8 0.5 0.19 11.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KXX76438.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX76438.1 - 0.1 12.8 0.1 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KXX76438.1 - 0.14 11.5 2.4 7.8 5.8 0.1 3.1 2 1 1 3 3 3 0 AAA-like domain CPT PF07931.7 KXX76438.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pmp3 PF01679.12 KXX76439.1 - 3.6e-19 68.2 5.5 5e-19 67.7 3.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator IPK PF03770.11 KXX76440.1 - 5.3e-51 173.0 0.0 7.4e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KXX76441.1 - 4.7e-37 127.7 0.5 1e-18 67.3 0.0 3.4 3 1 0 3 3 3 3 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PQ-loop PF04193.9 KXX76442.1 - 3.8e-41 138.4 9.1 7.9e-21 73.3 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_C_asm PF01578.15 KXX76442.1 - 2.1 7.8 6.6 13 5.3 0.3 2.5 2 0 0 2 2 2 0 Cytochrome C assembly protein Clp1 PF06807.9 KXX76443.1 - 2.1e-25 89.6 0.0 3.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KXX76443.1 - 1.8e-05 24.5 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KXX76443.1 - 0.0047 16.8 0.0 0.036 14.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KXX76443.1 - 0.0092 15.8 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KXX76443.1 - 0.031 13.3 0.1 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_16 PF13191.1 KXX76443.1 - 0.043 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 KXX76443.1 - 0.12 12.0 0.0 0.73 9.4 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 KXX76443.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX76443.1 - 0.16 11.7 3.1 0.56 9.9 0.7 2.3 2 0 0 2 2 2 0 Part of AAA domain Velvet PF11754.3 KXX76444.1 - 1.9e-55 187.5 0.0 3.9e-55 186.6 0.0 1.5 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.11 KXX76446.1 - 1.1e-18 67.1 41.4 1.1e-18 67.1 28.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KXX76446.1 - 9.7e-08 30.8 12.5 9.7e-08 30.8 8.6 2.5 1 1 0 2 2 2 2 MFS/sugar transport protein ECH PF00378.15 KXX76447.1 - 4.7e-23 81.5 0.0 1.2e-22 80.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 KXX76448.1 - 4.7e-23 81.5 0.0 1.2e-22 80.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 KXX76449.1 - 1.1e-18 67.1 41.4 1.1e-18 67.1 28.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KXX76449.1 - 9.7e-08 30.8 12.5 9.7e-08 30.8 8.6 2.5 1 1 0 2 2 2 2 MFS/sugar transport protein Vps51 PF08700.6 KXX76450.1 - 1.4e-13 50.4 0.0 3.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Death PF00531.17 KXX76450.1 - 0.05 13.3 1.5 0.23 11.2 0.0 2.9 3 0 0 3 3 3 0 Death domain Vps51 PF08700.6 KXX76451.1 - 1.4e-13 50.4 0.0 3.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Death PF00531.17 KXX76451.1 - 0.05 13.3 1.5 0.23 11.2 0.0 2.9 3 0 0 3 3 3 0 Death domain DsbB PF02600.11 KXX76452.1 - 0.033 13.9 3.0 0.09 12.5 2.0 1.7 1 1 1 2 2 2 0 Disulfide bond formation protein DsbB TPT PF03151.11 KXX76452.1 - 0.23 11.1 7.8 0.34 10.5 5.4 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family GNVR PF13807.1 KXX76452.1 - 6 6.6 5.5 0.78 9.5 0.4 1.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase PQ-loop PF04193.9 KXX76454.1 - 3.8e-41 138.4 9.1 7.9e-21 73.3 1.3 2.7 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_C_asm PF01578.15 KXX76454.1 - 2.1 7.8 6.6 13 5.3 0.3 2.5 2 0 0 2 2 2 0 Cytochrome C assembly protein Cullin PF00888.17 KXX76455.1 - 2.3e-114 383.0 0.0 4.1e-114 382.2 0.0 1.4 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KXX76455.1 - 1.8e-25 88.5 0.1 3.8e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain U1snRNP70_N PF12220.3 KXX76456.1 - 5.1e-33 113.2 3.1 9.1e-33 112.4 2.1 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KXX76456.1 - 1.3e-15 56.7 0.1 5.9e-15 54.6 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX76456.1 - 7e-11 41.9 0.1 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX76456.1 - 5.5e-08 32.5 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 KXX76457.1 - 3.3e-15 55.5 0.0 4.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 KXX76458.1 - 2.7e-92 308.2 0.5 3e-92 308.0 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U3_snoRNA_assoc PF08297.6 KXX76459.1 - 3.3e-12 46.4 1.9 3.3e-12 46.4 1.3 3.2 2 1 0 2 2 2 1 U3 snoRNA associated RRP7 PF12923.2 KXX76459.1 - 1.8 8.6 14.3 2.2 8.2 8.5 2.3 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF2992 PF11208.3 KXX76459.1 - 3.1 7.7 11.1 4.9 7.0 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) DUF3366 PF11846.3 KXX76459.1 - 5.6 6.7 5.8 13 5.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_2 PF07719.12 KXX76460.1 - 1.6e-06 27.6 1.4 0.016 15.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76460.1 - 5.3e-06 26.9 10.6 0.002 18.7 1.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX76460.1 - 0.00014 21.4 0.2 0.0013 18.2 0.1 2.4 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KXX76460.1 - 0.00038 19.9 0.1 0.058 13.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76460.1 - 0.027 14.4 4.8 0.21 11.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76460.1 - 0.051 13.3 1.2 10 6.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX76460.1 - 0.099 13.1 3.7 1.3 9.5 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76460.1 - 0.8 10.5 12.4 0.4 11.4 1.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KXX76460.1 - 9.2 6.3 7.9 4.4 7.3 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PTS_2-RNA PF01885.11 KXX76462.1 - 7.6e-66 220.9 0.0 9.3e-66 220.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KXX76462.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 La domain F-box-like PF12937.2 KXX76463.1 - 6.8e-09 35.3 0.2 2.6e-08 33.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KXX76463.1 - 4.3e-08 32.4 0.3 0.36 11.0 0.0 6.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 KXX76463.1 - 2.3e-06 27.0 1.4 1.3 8.7 0.0 5.6 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KXX76463.1 - 1.1e-05 24.9 0.3 4.1e-05 23.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 KXX76463.1 - 0.00016 21.2 9.2 0.5 10.5 0.0 6.1 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 KXX76463.1 - 0.00038 20.1 0.6 0.11 12.2 0.1 4.2 4 1 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 KXX76463.1 - 0.055 13.6 9.5 32 5.3 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat GRP PF07172.6 KXX76463.1 - 1.8 9.1 12.1 3.2 8.2 8.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.20 KXX76464.1 - 1.7e-57 194.5 0.0 2.5e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76464.1 - 5.5e-20 71.5 0.0 8.6e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX76464.1 - 1.1e-07 31.1 0.0 1.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX76464.1 - 9e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX76464.1 - 2.3e-05 24.2 0.4 0.0038 16.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KXX76464.1 - 0.0069 15.7 0.2 0.015 14.6 0.1 1.6 1 1 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 KXX76464.1 - 0.049 14.0 0.0 0.55 10.6 0.0 2.8 3 0 0 3 3 3 0 PAS domain UAA PF08449.6 KXX76465.1 - 8.8e-70 235.0 5.8 2.6e-69 233.4 4.0 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KXX76465.1 - 3e-10 40.2 20.6 2.1e-06 27.7 2.3 3.5 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 KXX76465.1 - 6.5e-07 28.6 3.4 0.0029 16.7 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KXX76465.1 - 2.7e-05 24.3 20.5 0.00043 20.4 3.9 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KXX76465.1 - 0.0014 18.3 7.7 0.0014 18.3 5.3 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family PsaX PF08078.7 KXX76465.1 - 0.19 11.7 0.2 0.19 11.7 0.1 2.6 3 0 0 3 3 3 0 PsaX family DSPc PF00782.15 KXX76467.1 - 5.3e-24 84.3 0.1 3.4e-22 78.4 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KXX76467.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KXX76467.1 - 0.22 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase KH_1 PF00013.24 KXX76468.1 - 5.7e-39 131.5 12.1 3.3e-15 55.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KXX76468.1 - 3.3e-30 103.1 13.5 1.3e-11 43.8 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KXX76468.1 - 2.1e-09 36.8 9.9 0.012 15.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KXX76468.1 - 1.1e-08 34.6 3.3 0.049 13.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KXX76468.1 - 0.00031 20.4 4.6 0.64 9.8 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KXX76468.1 - 0.004 16.6 0.6 0.4 10.1 0.1 3.1 3 0 0 3 3 3 1 dUTPase zf-RING_2 PF13639.1 KXX76469.1 - 0.0091 15.8 5.1 0.0091 15.8 3.5 2.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KXX76469.1 - 0.013 15.6 4.1 0.048 13.7 2.9 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KXX76469.1 - 5.8 7.0 12.5 0.087 12.8 1.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2361 PF10153.4 KXX76470.1 - 5.7e-37 126.3 8.4 5.7e-37 126.3 5.8 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) TP1 PF02079.11 KXX76470.1 - 0.015 15.0 0.6 0.015 15.0 0.4 2.1 2 0 0 2 2 2 0 Nuclear transition protein 1 DUF4522 PF15022.1 KXX76470.1 - 0.15 11.8 2.3 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Mnd1 PF03962.10 KXX76470.1 - 2.7 7.6 13.5 0.49 10.0 3.1 2.2 2 0 0 2 2 2 0 Mnd1 family zf-C2H2 PF00096.21 KXX76472.1 - 2.1e-08 34.0 19.5 3e-06 27.2 2.5 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX76472.1 - 2.5e-05 24.3 17.1 0.00018 21.6 0.6 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX76472.1 - 2.5e-05 24.3 3.8 2.5e-05 24.3 2.7 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX76472.1 - 0.00025 21.0 1.0 0.00025 21.0 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KXX76472.1 - 0.00054 19.7 4.3 0.22 11.4 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KXX76472.1 - 0.021 15.0 2.0 0.22 11.8 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KXX76472.1 - 0.075 13.4 3.3 0.18 12.2 2.3 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger DUF629 PF04780.7 KXX76472.1 - 0.39 9.1 3.8 4.9 5.5 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KXX76472.1 - 2.7 8.1 9.8 2.9 8.0 4.3 2.9 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 KXX76472.1 - 7.4 7.0 6.6 0.78 10.0 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain STE3 PF02076.10 KXX76474.1 - 1.1e-42 146.0 14.4 1.4e-42 145.6 10.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF605 PF04652.11 KXX76474.1 - 2.7 7.2 19.0 3.8 6.8 13.2 1.1 1 0 0 1 1 1 0 Vta1 like 7tm_7 PF08395.7 KXX76474.1 - 8.8 5.2 14.7 0.51 9.2 3.8 2.4 2 1 0 2 2 2 0 7tm Chemosensory receptor SSB PF00436.20 KXX76475.1 - 5.7e-18 64.6 0.0 6.9e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GIDA PF01134.17 KXX76476.1 - 9.2e-156 518.6 0.0 1.1e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KXX76476.1 - 1.4e-07 30.9 0.3 2.1e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX76476.1 - 2.7e-06 27.3 0.5 6.1e-06 26.2 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX76476.1 - 0.0003 19.8 3.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KXX76476.1 - 0.00085 18.9 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KXX76476.1 - 0.0042 15.6 1.3 0.083 11.3 0.6 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KXX76476.1 - 0.0052 15.6 5.8 0.0052 15.6 4.0 2.2 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 KXX76476.1 - 0.027 14.7 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KXX76476.1 - 0.13 12.3 2.0 4.1 7.4 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Adap_comp_sub PF00928.16 KXX76477.1 - 3.6e-86 288.5 0.0 4.8e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KXX76477.1 - 2.9e-05 23.7 0.2 5.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 KXX76477.1 - 0.022 14.6 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) ketoacyl-synt PF00109.21 KXX76480.1 - 2.7e-66 223.6 2.2 8.2e-66 222.0 0.2 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX76480.1 - 3e-57 193.2 2.9 8.1e-57 191.8 2.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KXX76480.1 - 1.8e-53 181.9 0.4 3.8e-53 180.8 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KXX76480.1 - 6.1e-47 160.2 0.1 1.4e-46 159.0 0.1 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX76480.1 - 9.2e-46 155.7 3.3 9.2e-46 155.7 2.3 2.9 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX76480.1 - 3.9e-39 133.1 0.3 1e-38 131.8 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX76480.1 - 4.5e-11 43.0 0.0 2e-10 41.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX76480.1 - 3e-10 40.0 0.0 1.5e-09 37.7 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX76480.1 - 2.8e-07 30.9 0.0 4.4e-06 27.0 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76480.1 - 1.2e-06 28.1 0.0 7.5e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76480.1 - 1.3e-06 28.9 0.3 0.0002 21.8 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KXX76480.1 - 0.00014 22.0 0.2 0.0004 20.5 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Saccharop_dh PF03435.13 KXX76480.1 - 0.00018 20.6 0.3 0.0003 19.8 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KXX76480.1 - 0.002 17.5 0.1 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KXX76480.1 - 0.043 13.0 0.4 0.094 11.9 0.2 1.6 1 0 0 1 1 1 0 NmrA-like family PCMT PF01135.14 KXX76480.1 - 0.097 12.1 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BAF1_ABF1 PF04684.8 KXX76480.1 - 0.75 8.5 0.2 1.4 7.7 0.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Transferase PF02458.10 KXX76481.1 - 5.1e-14 51.5 0.0 8.2e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 Transferase family p450 PF00067.17 KXX76482.1 - 4.8e-51 173.7 0.0 6.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3989 PF13150.1 KXX76482.1 - 0.31 10.4 0.9 18 4.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) p450 PF00067.17 KXX76483.1 - 6.2e-39 133.7 0.0 1.9e-30 105.7 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 KXX76484.1 - 6.2e-26 90.5 3.9 1.3e-25 89.5 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX76484.1 - 0.011 15.5 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 0 Berberine and berberine like Transferase PF02458.10 KXX76485.1 - 8e-37 126.6 0.0 3.6e-30 104.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family p450 PF00067.17 KXX76486.1 - 1.4e-58 198.5 0.0 5e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 DUF3099 PF11298.3 KXX76486.1 - 0.086 12.5 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Adap_comp_sub PF00928.16 KXX76487.1 - 4.3e-90 301.3 0.0 5.7e-90 300.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KXX76487.1 - 5.8e-09 35.7 0.2 9.6e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.20 KXX76489.1 - 7.6e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX76489.1 - 4.2e-10 39.5 0.0 5.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX76489.1 - 0.0039 16.9 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX76489.1 - 0.0049 16.8 0.0 0.03 14.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 KXX76490.1 - 7.8e-20 71.7 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX76490.1 - 1.9e-18 66.6 0.0 4.5e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KXX76490.1 - 5.9e-08 31.5 0.1 0.0036 15.8 0.1 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KXX76490.1 - 3.2e-05 23.2 0.0 0.0095 15.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KXX76490.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KXX76490.1 - 0.00026 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) ketoacyl-synt PF00109.21 KXX76491.1 - 2.2e-63 214.1 0.0 5.2e-63 212.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX76491.1 - 2.8e-55 186.7 0.8 7.3e-55 185.4 0.5 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KXX76491.1 - 8.6e-53 179.4 0.0 1.4e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KXX76491.1 - 3.6e-52 177.6 0.0 5.5e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KXX76491.1 - 8.2e-41 139.6 5.5 1.1e-40 139.2 0.5 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX76491.1 - 4.6e-34 116.8 0.6 2.1e-33 114.7 0.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX76491.1 - 6e-19 67.8 0.0 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX76491.1 - 5.1e-11 43.5 0.0 3.8e-10 40.7 0.0 2.6 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX76491.1 - 2.3e-09 36.9 0.8 4.9e-09 35.9 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KXX76491.1 - 0.00022 21.3 0.0 0.00068 19.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KXX76491.1 - 0.0052 15.7 0.1 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SpoVAD PF07451.6 KXX76491.1 - 0.01 14.2 0.1 0.021 13.2 0.1 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.5 KXX76491.1 - 0.16 11.6 4.8 0.18 11.4 0.0 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF676 PF05057.9 KXX76491.1 - 0.49 9.6 0.1 0.96 8.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Opi1 PF08618.5 KXX76492.1 - 2.4e-72 244.2 0.0 4.7e-42 144.3 0.1 3.4 1 1 2 3 3 3 3 Transcription factor Opi1 Hydrolase_like PF13242.1 KXX76493.1 - 7.9e-07 28.6 0.0 2.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KXX76493.1 - 3.6e-06 27.3 0.0 0.0013 18.9 0.0 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX76493.1 - 0.14 12.5 0.0 0.52 10.6 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MBF1 PF08523.5 KXX76494.1 - 1.1e-23 83.0 1.1 2.1e-23 82.1 0.7 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KXX76494.1 - 9.6e-13 47.7 0.0 1.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KXX76494.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KXX76494.1 - 5.9e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain ADH_zinc_N PF00107.21 KXX76496.1 - 2e-23 82.3 0.2 3.3e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX76496.1 - 2e-19 70.7 0.0 6.2e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX76496.1 - 2.3e-11 43.4 0.0 1.5e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_4 PF02056.11 KXX76497.1 - 0.079 12.2 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase RVT_thumb PF06817.9 KXX76498.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain DLH PF01738.13 KXX76499.1 - 2e-20 73.0 0.1 1e-18 67.4 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX76499.1 - 7e-08 32.3 0.3 1.1e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX76499.1 - 3e-07 30.5 0.7 4.9e-05 23.3 0.1 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX76499.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1365 PF07103.6 KXX76500.1 - 4.1e-34 117.7 0.0 2.7e-33 115.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.9 KXX76501.1 - 4.8e-21 74.4 0.0 7e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KXX76501.1 - 0.1 12.2 0.2 0.1 12.2 0.1 2.6 3 0 0 3 3 3 0 Nudix N-terminal PTCB-BRCT PF12738.2 KXX76502.1 - 6.4e-05 22.7 0.4 0.00023 20.9 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KXX76502.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.23 KXX76503.1 - 2.4e-78 263.3 0.0 2.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX76503.1 - 3e-12 47.3 0.0 1.1e-11 45.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1667 PF07892.6 KXX76503.1 - 0.088 12.5 0.0 4.2 7.1 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1667) CDC14 PF08045.6 KXX76504.1 - 4.6e-88 294.6 0.0 5.3e-88 294.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component KilA-N PF04383.8 KXX76506.1 - 0.00026 20.5 0.0 0.0039 16.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Pkinase PF00069.20 KXX76507.1 - 3.1e-57 193.7 0.0 4.4e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76507.1 - 9.1e-21 74.0 0.3 1.5e-20 73.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KXX76507.1 - 0.017 14.8 0.0 0.077 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX76507.1 - 0.081 12.4 0.7 0.16 11.5 0.5 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase polyprenyl_synt PF00348.12 KXX76508.1 - 7e-67 225.0 0.0 8.4e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Pex24p PF06398.6 KXX76509.1 - 2e-96 322.9 0.0 2.7e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pex14_N PF04695.8 KXX76509.1 - 0.072 13.1 1.1 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ten1 PF12658.2 KXX76512.1 - 8e-29 99.9 0.0 9.2e-29 99.7 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Snf7 PF03357.16 KXX76513.1 - 1.1e-31 109.5 16.1 1.1e-31 109.5 11.1 2.0 2 0 0 2 2 2 1 Snf7 MutS_III PF05192.13 KXX76513.1 - 0.014 15.1 2.0 0.019 14.7 1.4 1.2 1 0 0 1 1 1 0 MutS domain III DUF465 PF04325.8 KXX76513.1 - 0.13 11.9 11.4 0.26 11.0 1.5 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF465) CAP_N PF01213.14 KXX76513.1 - 0.14 11.3 1.9 0.28 10.4 1.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BLOC1_2 PF10046.4 KXX76513.1 - 3.3 7.9 10.1 1.6 8.9 1.4 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.4 KXX76513.1 - 4.5 5.9 14.7 0.25 10.0 5.7 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 UreD PF01774.12 KXX76514.1 - 3.4e-59 199.8 0.0 4.2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.9 KXX76515.1 - 2.9e-22 79.0 1.2 2.5e-21 76.0 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase III RPC4 Med3 PF11593.3 KXX76515.1 - 2.7 7.1 18.9 4.7 6.3 13.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FXR1P_C PF12235.3 KXX76515.1 - 7.7 6.6 20.0 3.2 7.8 3.9 3.1 3 0 0 3 3 3 0 Fragile X-related 1 protein C terminal FAD_binding_3 PF01494.14 KXX76516.1 - 6.3e-15 55.0 0.1 6.5e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX76516.1 - 6.7e-11 41.6 6.8 7.6e-07 28.3 0.9 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX76516.1 - 2.6e-06 26.6 0.6 0.016 14.1 0.4 2.0 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX76516.1 - 0.00015 21.6 0.0 0.00054 19.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX76516.1 - 0.00031 19.3 0.0 0.00056 18.4 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KXX76516.1 - 0.0005 20.0 0.1 0.0015 18.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX76516.1 - 0.00061 19.9 0.1 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX76516.1 - 0.0027 16.6 2.1 0.0027 16.6 1.5 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX76516.1 - 0.0027 18.0 0.2 0.064 13.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX76516.1 - 0.13 10.8 0.2 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX76516.1 - 0.15 11.8 1.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KXX76516.1 - 0.18 10.6 0.3 0.27 10.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 KXX76517.1 - 1.9e-29 102.5 40.7 1.9e-29 102.5 28.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 KXX76517.1 - 9.3 5.8 11.4 0.11 12.0 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) HA2 PF04408.18 KXX76518.1 - 9.9e-21 73.6 2.0 2.2e-20 72.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KXX76518.1 - 8.4e-14 51.2 0.0 2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KXX76518.1 - 2.1e-11 43.6 0.0 8.8e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KXX76518.1 - 6e-09 35.6 0.1 1.5e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 KXX76518.1 - 3.4e-06 26.9 0.1 9.5e-06 25.4 0.1 1.8 1 0 0 1 1 1 1 RWD domain AAA_19 PF13245.1 KXX76518.1 - 8.1e-05 22.3 0.4 0.00071 19.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KXX76518.1 - 0.00015 21.9 0.1 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UBA PF00627.26 KXX76518.1 - 0.0053 16.5 1.1 0.02 14.7 0.0 2.6 3 0 0 3 3 2 1 UBA/TS-N domain AAA_29 PF13555.1 KXX76518.1 - 0.0056 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KXX76518.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KXX76518.1 - 0.035 14.4 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KXX76518.1 - 0.05 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zot PF05707.7 KXX76518.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DND1_DSRM PF14709.1 KXX76518.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.6 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KXX76518.1 - 0.34 11.5 2.6 11 6.6 0.0 3.2 3 0 0 3 3 2 0 Double-stranded RNA binding motif Arm PF00514.18 KXX76519.1 - 3.1e-82 267.9 13.1 1.9e-13 49.6 0.1 7.3 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KXX76519.1 - 6.6e-23 80.7 0.2 7.1e-08 32.6 0.0 5.0 1 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 KXX76519.1 - 8.2e-20 70.7 6.4 9.7e-06 25.9 0.0 6.1 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KXX76519.1 - 1.9e-18 64.8 1.0 6.9e-07 28.8 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.15 KXX76519.1 - 1.4e-16 60.3 2.8 2.6e-16 59.5 1.9 1.4 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 KXX76519.1 - 1.7e-09 37.2 0.0 0.015 14.4 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KXX76519.1 - 6.7e-05 21.4 0.0 0.0063 14.8 0.0 2.5 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KXX76519.1 - 0.00087 19.1 0.0 1.3 8.9 0.0 4.2 2 1 3 5 5 5 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 KXX76519.1 - 0.01 14.1 0.2 0.28 9.4 0.0 2.6 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KXX76519.1 - 0.013 15.9 0.1 0.59 10.7 0.0 3.4 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat SURF6 PF04935.7 KXX76519.1 - 3.8 6.7 8.1 5.7 6.1 5.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 KXX76520.1 - 8.2e-16 58.2 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 STAG PF08514.6 KXX76521.1 - 3e-31 107.5 1.0 7.1e-31 106.3 0.7 1.6 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KXX76521.1 - 1.3e-12 47.7 0.2 1.5e-05 25.2 0.0 3.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 KXX76521.1 - 0.0045 16.9 0.2 26 5.2 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat DUF1664 PF07889.7 KXX76521.1 - 0.0061 16.3 0.8 4.3 7.1 0.5 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Nipped-B_C PF12830.2 KXX76521.1 - 0.19 11.3 1.1 3.1 7.4 0.0 3.3 4 1 0 4 4 4 0 Sister chromatid cohesion C-terminus ICE2 PF08426.5 KXX76522.1 - 1.2e-147 491.8 13.7 1.4e-147 491.6 9.5 1.0 1 0 0 1 1 1 1 ICE2 AT_hook PF02178.14 KXX76523.1 - 0.0019 17.6 39.5 0.029 14.0 0.3 4.8 4 0 0 4 4 4 4 AT hook motif DUF4616 PF15394.1 KXX76523.1 - 0.024 13.6 2.7 0.032 13.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) MSP1_C PF07462.6 KXX76523.1 - 0.026 12.9 9.6 0.036 12.4 6.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Herpes_gE PF02480.11 KXX76523.1 - 0.08 11.1 1.4 0.11 10.7 1.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 KXX76524.1 - 1.8e-32 112.4 34.0 1.8e-32 112.4 23.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KXX76524.1 - 0.0056 16.1 2.0 0.0056 16.1 1.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KXX76524.1 - 0.0091 14.6 24.2 0.084 11.4 16.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Mito_carr PF00153.22 KXX76526.1 - 3.5e-74 244.5 0.2 5.1e-26 90.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KXX76526.1 - 5.7e-15 53.4 1.5 1.7e-07 30.0 0.0 5.2 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KXX76526.1 - 4.9e-14 50.8 0.5 4.2e-06 26.1 0.0 5.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 KXX76526.1 - 1e-13 51.1 2.3 2e-07 31.0 0.3 3.9 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KXX76526.1 - 4.1e-13 48.7 1.3 0.033 13.8 0.0 4.8 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KXX76526.1 - 2.7e-10 39.0 0.3 2.5e-06 26.5 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KXX76526.1 - 0.023 14.6 0.0 26 4.8 0.0 4.2 4 0 0 4 4 4 0 EF-hand domain ADH_zinc_N PF00107.21 KXX76527.1 - 6.6e-09 35.4 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX76527.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PQ-loop PF04193.9 KXX76528.1 - 5.4e-31 105.9 10.1 1.3e-15 56.7 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat Vma12 PF11712.3 KXX76528.1 - 0.0088 15.7 2.2 0.019 14.6 1.1 1.9 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF606 PF04657.8 KXX76528.1 - 0.048 13.7 0.9 0.85 9.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF606 Cyclin_N PF00134.18 KXX76529.1 - 2.6e-42 143.3 0.3 4.1e-42 142.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KXX76529.1 - 8.2e-33 112.8 0.0 2.1e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 KXX76530.1 - 0.00075 19.3 12.4 0.0015 18.4 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KXX76530.1 - 0.023 13.8 0.1 0.068 12.4 0.0 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ Transp_cyt_pur PF02133.10 KXX76532.1 - 3.2e-38 131.4 31.4 5.8e-37 127.2 21.7 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DNA_ligase_A_M PF01068.16 KXX76533.1 - 1.5e-20 73.4 0.0 3.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KXX76533.1 - 2.6e-13 50.1 0.0 5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus Ribonuc_P_40 PF08584.6 KXX76533.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF1115 PF06544.7 KXX76534.1 - 0.00031 20.4 0.3 0.0025 17.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) MS_channel PF00924.13 KXX76536.1 - 5.7e-20 71.5 2.6 1.1e-19 70.6 1.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 KXX76536.1 - 0.014 15.5 0.1 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KXX76536.1 - 0.038 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 KXX76536.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KXX76536.1 - 0.08 12.2 0.4 0.2 11.0 0.3 1.8 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.3 KXX76536.1 - 3.3 7.7 6.6 0.36 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function Peptidase_A4 PF01828.12 KXX76537.1 - 1.2e-21 76.7 0.4 5.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase A4 family EXS PF03124.9 KXX76538.1 - 3.9e-94 315.5 24.9 4.8e-94 315.2 17.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KXX76538.1 - 3e-61 207.6 0.9 4.8e-60 203.6 0.0 2.2 2 0 0 2 2 2 1 SPX domain NDK PF00334.14 KXX76539.1 - 1.7e-54 183.2 0.0 1.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyoxalase PF00903.20 KXX76540.1 - 2.6e-07 30.6 0.1 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX76540.1 - 6.7e-07 29.8 0.1 8.3e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain GCD14 PF08704.5 KXX76541.1 - 6.4e-64 215.8 0.0 1.9e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KXX76541.1 - 0.00044 20.2 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76541.1 - 0.018 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2580 PF10824.3 KXX76542.1 - 0.001 19.3 1.2 0.001 19.3 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2580) CAF1A PF12253.3 KXX76543.1 - 8.8e-23 80.2 2.4 8.8e-23 80.2 1.6 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A HflK_N PF12221.3 KXX76543.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal CAF-1_p150 PF11600.3 KXX76543.1 - 0.15 11.4 59.9 4.6 6.5 41.5 2.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMEM247 PF15444.1 KXX76543.1 - 0.27 11.0 14.4 0.43 10.3 0.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 247 Ycf1 PF05758.7 KXX76543.1 - 1.7 6.2 14.8 2.6 5.6 10.2 1.2 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 KXX76543.1 - 1.9 7.8 30.0 0.042 13.2 15.9 1.9 2 0 0 2 2 2 0 DDRGK domain PAF-AH_p_II PF03403.8 KXX76545.1 - 1.8e-43 148.2 0.0 3.7e-36 124.2 0.0 2.2 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KXX76545.1 - 1.4e-11 44.3 0.0 2.9e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX76545.1 - 6.6e-08 32.7 0.2 1.5e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX76545.1 - 0.012 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 KXX76545.1 - 0.013 14.4 0.0 0.034 13.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KXX76545.1 - 0.021 13.6 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FLILHELTA PF10306.4 KXX76546.1 - 3.2e-26 91.1 0.0 5.6e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KXX76546.1 - 0.0099 16.1 0.4 0.017 15.3 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_M18 PF02127.10 KXX76547.1 - 1.4e-123 412.6 0.0 1.6e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.1 KXX76547.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family Peptidase_M50B PF13398.1 KXX76548.1 - 6.3e-58 195.4 17.5 8.1e-58 195.1 12.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Na_Pi_cotrans PF02690.10 KXX76548.1 - 0.013 15.1 2.1 0.013 15.1 1.5 2.2 2 1 0 2 2 2 0 Na+/Pi-cotransporter Peptidase_M41 PF01434.13 KXX76548.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M50 PF02163.17 KXX76548.1 - 0.091 11.7 4.7 0.026 13.4 0.9 2.2 2 1 0 2 2 2 0 Peptidase family M50 Glyco_hydro_31 PF01055.21 KXX76549.1 - 2e-153 511.3 4.0 2.6e-153 511.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX76549.1 - 1.1e-24 85.9 0.4 4.7e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DIOX_N PF14226.1 KXX76551.1 - 2.6e-19 69.8 0.0 4.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX76551.1 - 1.8e-11 44.1 0.0 5.3e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec39 PF08314.6 KXX76552.1 - 1.5e-231 770.2 0.0 1.8e-231 769.9 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Prp19_bind PF06991.6 KXX76553.1 - 1.6e-48 165.3 33.8 1.6e-48 165.3 23.4 2.5 3 1 1 4 4 4 1 Splicing factor, Prp19-binding domain Voldacs PF03517.8 KXX76555.1 - 3.1e-22 78.8 0.5 3.1e-22 78.8 0.3 1.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling ADH_zinc_N_2 PF13602.1 KXX76556.1 - 3.2e-18 66.8 0.0 6.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX76556.1 - 3.2e-08 33.1 0.0 5.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KXX76556.1 - 0.026 14.4 0.1 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Eno-Rase_NADH_b PF12242.3 KXX76556.1 - 0.042 13.6 1.1 0.083 12.6 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2855 PF11017.3 KXX76556.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) CRAL_TRIO PF00650.15 KXX76557.1 - 9.7e-41 138.9 0.0 1.4e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX76557.1 - 4.7e-08 33.0 0.7 9.5e-08 32.0 0.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KXX76557.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 KXX76558.1 - 2.7e-63 213.8 0.0 3.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KXX76558.1 - 4.8e-40 137.0 0.0 6.7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PAN_1 PF00024.21 KXX76559.1 - 6.1e-06 25.8 0.1 1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 KXX76559.1 - 1e-05 24.8 0.0 2.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KXX76559.1 - 0.00032 20.3 0.0 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Dzip-like_N PF13815.1 KXX76560.1 - 0.0042 16.8 4.1 0.39 10.5 0.5 2.6 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal AAA_13 PF13166.1 KXX76560.1 - 0.005 15.3 0.8 0.0078 14.7 0.5 1.3 1 0 0 1 1 1 1 AAA domain DUF2046 PF09755.4 KXX76560.1 - 0.0078 15.1 3.6 0.045 12.6 1.5 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Spc24 PF08286.6 KXX76560.1 - 0.015 15.0 2.9 0.029 14.0 0.7 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 KXX76560.1 - 0.017 15.0 1.1 3.2 7.7 0.3 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KXX76560.1 - 0.018 14.1 10.5 0.044 12.8 2.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2353 PF09789.4 KXX76560.1 - 0.024 13.9 3.9 0.035 13.3 2.7 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) SseC PF04888.7 KXX76560.1 - 0.028 13.7 1.5 0.039 13.2 1.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DMPK_coil PF08826.5 KXX76560.1 - 0.033 14.0 2.9 0.033 14.0 2.0 3.2 4 0 0 4 4 3 0 DMPK coiled coil domain like DUF342 PF03961.8 KXX76560.1 - 0.037 12.4 1.7 0.049 12.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.15 KXX76560.1 - 0.044 13.5 10.9 0.088 12.5 3.0 3.1 3 0 0 3 3 3 0 Prefoldin subunit Lzipper-MIP1 PF14389.1 KXX76560.1 - 0.057 13.5 9.1 2.3 8.4 5.3 3.3 2 1 0 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 THOC7 PF05615.8 KXX76560.1 - 0.065 13.4 7.0 0.11 12.7 2.5 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Kinesin-relat_1 PF12711.2 KXX76560.1 - 0.075 13.4 8.6 0.14 12.5 2.7 2.9 3 0 0 3 3 3 0 Kinesin motor WEMBL PF05701.6 KXX76560.1 - 0.11 10.8 10.5 0.38 9.1 7.3 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4407 PF14362.1 KXX76560.1 - 0.12 11.3 5.3 0.17 10.8 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 KXX76560.1 - 0.12 12.1 16.0 0.41 10.4 6.1 3.5 3 1 0 3 3 2 0 Homeobox associated leucine zipper Nnf1 PF03980.9 KXX76560.1 - 0.15 12.0 5.1 0.15 12.0 1.5 2.5 2 1 0 2 2 2 0 Nnf1 ADIP PF11559.3 KXX76560.1 - 0.16 11.8 7.1 0.064 13.1 1.3 2.5 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KXX76560.1 - 0.21 10.5 7.0 0.37 9.6 4.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 KXX76560.1 - 0.23 11.5 2.6 0.61 10.1 1.1 2.2 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 KXX76560.1 - 0.25 11.2 2.2 7.8 6.5 1.2 2.9 3 0 0 3 3 3 0 FlxA-like protein Rootletin PF15035.1 KXX76560.1 - 0.27 11.1 10.7 0.032 14.2 2.7 2.3 3 0 0 3 3 2 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 KXX76560.1 - 0.28 10.8 9.9 0.028 14.1 1.8 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KXX76560.1 - 0.33 10.7 14.7 0.079 12.7 4.3 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.1 KXX76560.1 - 0.34 10.7 3.7 0.37 10.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) ATG16 PF08614.6 KXX76560.1 - 0.37 10.6 14.1 0.53 10.0 8.0 2.4 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 KXX76560.1 - 0.39 10.5 12.1 0.85 9.4 4.0 2.2 2 0 0 2 2 2 0 Rabaptin-like protein Spc7 PF08317.6 KXX76560.1 - 0.41 9.2 6.2 0.86 8.1 4.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Ax_dynein_light PF10211.4 KXX76560.1 - 0.43 10.3 10.2 0.043 13.6 2.6 2.3 3 0 0 3 3 2 0 Axonemal dynein light chain Kinetocho_Slk19 PF12709.2 KXX76560.1 - 0.5 10.4 7.3 3.1 7.9 2.3 3.1 2 2 0 2 2 2 0 Central kinetochore-associated DUF3450 PF11932.3 KXX76560.1 - 0.53 9.4 8.8 2.6 7.2 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 KXX76560.1 - 0.58 10.0 10.8 0.025 14.4 2.6 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KXX76560.1 - 0.72 9.4 15.4 0.22 11.0 4.4 2.8 2 1 1 3 3 3 0 IncA protein TBPIP PF07106.8 KXX76560.1 - 0.73 9.3 9.1 1.2 8.6 2.0 2.9 3 1 0 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF465 PF04325.8 KXX76560.1 - 0.79 9.4 11.1 1.5 8.5 3.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) CENP-Q PF13094.1 KXX76560.1 - 0.83 9.6 11.6 1.2 9.1 3.9 3.0 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.1 KXX76560.1 - 0.91 9.4 10.3 0.15 12.0 2.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Filament PF00038.16 KXX76560.1 - 1.2 8.5 12.2 0.44 9.9 3.0 2.6 2 1 0 3 3 3 0 Intermediate filament protein AATF-Che1 PF13339.1 KXX76560.1 - 1.5 9.0 6.6 1.1 9.3 0.6 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF4140 PF13600.1 KXX76560.1 - 1.5 9.2 13.0 1.5 9.2 3.3 3.6 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1640 PF07798.6 KXX76560.1 - 1.9 8.4 7.6 3.4 7.6 1.7 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1640) DUF4164 PF13747.1 KXX76560.1 - 2.2 8.4 14.4 5.4 7.2 2.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) AAA_23 PF13476.1 KXX76560.1 - 2.4 8.4 5.5 3.4 7.9 3.8 1.4 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 KXX76560.1 - 2.4 8.5 7.9 3.5 7.9 2.8 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF972) M PF02370.11 KXX76560.1 - 3.1 8.4 9.4 3 8.4 2.3 3.1 2 0 0 2 2 2 0 M protein repeat TSC22 PF01166.13 KXX76560.1 - 3.4 7.6 11.0 1.6 8.7 0.7 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Bap31 PF05529.7 KXX76560.1 - 3.6 7.0 8.0 27 4.1 5.5 2.2 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 KXX76560.1 - 4.3 6.8 20.3 2.5 7.6 2.7 4.3 4 1 1 5 5 4 0 Septum formation initiator DUF1049 PF06305.6 KXX76560.1 - 4.6 6.7 5.1 3.9 7.0 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) GAS PF13851.1 KXX76560.1 - 4.6 6.3 11.2 2.5 7.2 4.9 2.2 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 KXX76560.1 - 5.1 6.4 11.8 0.23 10.8 3.6 2.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4201) CCDC144C PF14915.1 KXX76560.1 - 5.1 5.9 13.8 0.85 8.4 5.0 2.3 2 1 0 3 3 2 0 CCDC144C protein coiled-coil region Sec2p PF06428.6 KXX76560.1 - 7.2 6.5 12.6 5.4 6.9 3.9 2.7 2 1 1 3 3 2 0 GDP/GTP exchange factor Sec2p IFP_35_N PF07334.8 KXX76560.1 - 7.3 6.6 8.4 13 5.8 2.8 3.0 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DivIVA PF05103.8 KXX76560.1 - 7.7 6.5 8.8 1.3 9.0 1.6 2.7 3 1 0 3 3 2 0 DivIVA protein DUF1192 PF06698.6 KXX76560.1 - 7.8 6.4 11.8 47 3.9 3.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) GrpE PF01025.14 KXX76560.1 - 8 5.9 15.4 0.71 9.3 4.3 2.6 2 1 1 3 3 2 0 GrpE CCDC155 PF14662.1 KXX76560.1 - 8.6 5.9 16.1 3.6 7.1 8.5 2.2 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 MerR-DNA-bind PF09278.6 KXX76560.1 - 9.4 6.7 13.8 11 6.5 0.0 3.8 2 1 2 4 4 4 0 MerR, DNA binding DUF3669 PF12417.3 KXX76562.1 - 8e-16 57.5 0.0 1.7e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein NACHT PF05729.7 KXX76563.1 - 2.9e-12 46.5 0.0 9.4e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX76563.1 - 1.4e-05 25.1 0.1 0.00032 20.7 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX76563.1 - 3.7e-05 23.8 0.0 8.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KXX76563.1 - 0.0009 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KXX76563.1 - 0.0032 18.2 0.0 0.02 15.7 0.0 2.2 1 1 0 2 2 1 1 AAA domain Aldolase_2 PF10120.4 KXX76563.1 - 0.0055 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative aldolase Mg_chelatase PF01078.16 KXX76563.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KXX76563.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA PF00004.24 KXX76563.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KXX76563.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX76563.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KXX76563.1 - 0.078 12.8 0.0 0.3 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX76563.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX76563.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 KXX76563.1 - 0.1 12.1 0.0 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 KXX76563.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TIP49 PF06068.8 KXX76563.1 - 0.24 10.0 0.0 0.38 9.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Rrp15p PF07890.7 KXX76565.1 - 6e-35 120.1 10.3 1.2e-34 119.1 7.2 1.5 1 0 0 1 1 1 1 Rrp15p DUF3022 PF11226.3 KXX76565.1 - 0.071 12.9 2.4 0.13 12.1 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) DUF605 PF04652.11 KXX76565.1 - 0.15 11.4 14.3 0.18 11.1 9.9 1.1 1 0 0 1 1 1 0 Vta1 like PNP_UDP_1 PF01048.15 KXX76569.1 - 1.3e-14 53.7 0.0 2.7e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KXX76569.1 - 4.1e-10 39.9 0.1 5.9e-07 29.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.17 KXX76569.1 - 6.8e-08 31.7 0.0 1.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KXX76569.1 - 0.00024 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KXX76569.1 - 0.0053 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KXX76569.1 - 0.0089 16.0 0.6 0.11 12.5 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KXX76569.1 - 0.0098 15.3 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX76569.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_14 PF13428.1 KXX76569.1 - 0.1 13.3 2.7 5.5 7.9 1.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fer2 PF00111.22 KXX76572.1 - 2.9e-13 49.3 0.7 5e-13 48.5 0.5 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 KXX76575.1 - 3.4e-15 55.5 1.8 0.0006 19.4 0.1 5.2 5 0 0 5 5 5 4 Mitochondrial carrier protein Glyco_hydro_61 PF03443.9 KXX76576.1 - 5.4e-81 271.5 0.1 7e-81 271.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX76576.1 - 6.2e-12 44.9 6.6 1.6e-11 43.6 4.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3669 PF12417.3 KXX76577.1 - 6.5e-23 80.2 0.2 1.3e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Transferase PF02458.10 KXX76578.1 - 1.3e-21 76.6 0.0 7.5e-18 64.1 0.0 3.2 2 1 0 2 2 2 2 Transferase family HET PF06985.6 KXX76579.1 - 1.9e-36 125.2 0.6 3.4e-36 124.4 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.21 KXX76579.1 - 0.0014 18.4 0.1 0.0031 17.3 0.1 1.6 1 0 0 1 1 1 1 WW domain CD99L2 PF12301.3 KXX76580.1 - 0.0044 16.7 1.2 0.013 15.1 0.8 1.8 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF3372 PF11852.3 KXX76580.1 - 0.1 11.7 0.2 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) MFS_1 PF07690.11 KXX76581.1 - 3.9e-24 85.0 27.3 3.9e-24 85.0 19.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.9 KXX76581.1 - 4.1 5.3 6.8 6 4.7 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.16 KXX76582.1 - 1.3e-50 170.7 0.0 5.2e-32 110.5 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KXX76582.1 - 1.7e-36 123.6 3.9 6.3e-27 92.9 0.3 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KXX76582.1 - 1.2e-30 106.2 0.1 2.9e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KXX76582.1 - 8.1e-22 76.3 2.4 6.6e-19 67.0 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KXX76582.1 - 0.094 12.9 0.0 4.4 7.6 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding FKBP_C PF00254.23 KXX76583.1 - 7.8e-27 93.1 0.0 9e-27 92.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HET PF06985.6 KXX76584.1 - 4.3e-23 82.0 8.0 3.5e-20 72.5 0.8 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Herpes_UL32 PF06070.6 KXX76584.1 - 0.039 12.4 1.4 0.059 11.8 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 WD40 PF00400.27 KXX76585.1 - 1.3e-15 56.5 4.4 2.2e-05 24.1 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Sigma70_ner PF04546.8 KXX76585.1 - 0.042 13.4 0.6 0.063 12.8 0.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Apc4_WD40 PF12894.2 KXX76585.1 - 0.09 12.2 0.1 9.7 5.7 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoplasmin PF03066.10 KXX76585.1 - 0.1 12.0 4.4 0.16 11.4 3.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KXX76585.1 - 6.3 5.4 14.5 11 4.6 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glycos_transf_4 PF00953.16 KXX76586.1 - 1.3e-32 112.7 10.6 1.3e-32 112.7 7.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 YdjC PF04794.7 KXX76587.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein ATP-synt_C PF00137.16 KXX76588.1 - 2.5e-16 59.3 10.5 5.1e-16 58.3 7.3 1.6 1 0 0 1 1 1 1 ATP synthase subunit C Inhibitor_I36 PF03995.8 KXX76588.1 - 0.08 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Asp_Glu_race_2 PF14669.1 KXX76588.1 - 0.13 11.5 0.2 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Putative aspartate racemase MOZ_SAS PF01853.13 KXX76589.1 - 9.3e-50 168.4 0.0 1.5e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family p450 PF00067.17 KXX76590.1 - 1.2e-07 30.7 0.0 1.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.20 KXX76591.1 - 0.0051 17.0 0.1 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RP1-2 PF12042.3 KXX76591.1 - 0.067 12.8 0.2 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain Hen1_L PF12623.2 KXX76591.1 - 0.09 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 GCR1_C PF12550.3 KXX76592.1 - 1.8e-19 69.3 1.2 3.6e-19 68.4 0.8 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 KXX76592.1 - 0.0044 17.1 0.5 0.038 14.1 0.1 2.6 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain F5_F8_type_C PF00754.20 KXX76592.1 - 0.036 13.8 0.3 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 F5/8 type C domain p450 PF00067.17 KXX76593.1 - 7.5e-46 156.6 0.0 1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4179 PF13786.1 KXX76594.1 - 1.8 8.8 2.7 1.1 9.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) GST_N_2 PF13409.1 KXX76596.1 - 4.4e-22 77.8 0.0 2.4e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX76596.1 - 1.6e-16 59.9 0.1 3.7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX76596.1 - 2.4e-06 27.4 0.0 5.4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX76596.1 - 3.9e-06 26.9 0.1 0.00024 21.2 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX76596.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UQ_con PF00179.21 KXX76597.1 - 1.6e-23 82.6 0.0 3.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.2 KXX76597.1 - 9.3e-21 73.9 0.6 3.4e-09 36.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76597.1 - 4.8e-18 63.9 2.7 0.0011 18.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KXX76597.1 - 2.8e-14 52.7 5.7 6.2e-05 23.1 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX76597.1 - 7e-13 48.7 0.8 1.8e-06 28.3 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.7 KXX76597.1 - 7e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 KXX76597.1 - 2.1e-09 36.7 0.3 0.024 14.8 0.0 5.2 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.1 KXX76597.1 - 2.5e-05 24.3 0.6 9.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX76597.1 - 0.00031 20.9 0.6 0.0016 18.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 KXX76597.1 - 0.14 11.1 0.2 12 4.8 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain DUF1191 PF06697.7 KXX76598.1 - 0.0016 17.2 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) RCR PF12273.3 KXX76598.1 - 0.0024 18.4 5.5 0.0024 18.4 3.8 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 KXX76598.1 - 0.0068 14.7 0.0 0.0068 14.7 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E ZYG-11_interact PF05884.7 KXX76598.1 - 0.12 11.4 0.4 0.17 10.9 0.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Glyoxalase_2 PF12681.2 KXX76599.1 - 5.2e-10 39.8 0.1 7.3e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KXX76599.1 - 3.9e-05 23.6 0.0 5.7e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1691 PF07950.6 KXX76599.1 - 0.035 14.0 0.3 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) PNP_UDP_1 PF01048.15 KXX76602.1 - 6.5e-16 58.0 0.0 2.6e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.1 KXX76602.1 - 3.7e-11 42.8 0.4 0.0013 18.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX76602.1 - 3e-08 32.8 0.0 8.3e-08 31.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 KXX76602.1 - 5.1e-05 22.7 0.0 0.00068 19.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain TPR_7 PF13176.1 KXX76602.1 - 0.00068 19.2 0.8 14 5.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76602.1 - 0.00077 19.8 2.3 3.6 8.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76602.1 - 0.0038 17.8 2.2 13 6.5 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX76602.1 - 0.0097 15.7 1.8 13 5.9 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 KXX76602.1 - 0.013 15.4 3.9 0.036 14.0 0.1 3.4 2 1 0 2 2 2 0 AAA ATPase domain TPR_10 PF13374.1 KXX76602.1 - 0.016 15.1 5.6 37 4.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_5 PF07728.9 KXX76602.1 - 0.021 14.5 1.1 0.26 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TPR_11 PF13414.1 KXX76602.1 - 0.15 11.7 0.4 22 4.7 0.1 2.8 1 1 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 KXX76602.1 - 0.35 11.2 3.2 7.5 6.9 0.0 4.2 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX76602.1 - 6.5 7.4 8.6 0.24 11.9 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Glyco_hydro_61 PF03443.9 KXX76603.1 - 2.5e-08 34.0 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 1-cysPrx_C PF10417.4 KXX76603.1 - 0.00067 19.2 0.4 0.046 13.3 0.0 2.4 2 0 0 2 2 2 2 C-terminal domain of 1-Cys peroxiredoxin Glyco_hydro_61 PF03443.9 KXX76604.1 - 8.2e-29 100.9 0.0 1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_48 PF02922.13 KXX76604.1 - 0.11 12.5 0.2 0.6 10.1 0.0 2.2 2 1 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) adh_short PF00106.20 KXX76605.1 - 1.2e-23 83.8 0.0 2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76605.1 - 8.8e-11 42.0 0.0 1.5e-10 41.2 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76605.1 - 1.3e-08 34.7 0.1 7.1e-08 32.3 0.1 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX76605.1 - 8.5e-08 32.4 0.9 2.2e-06 27.8 0.3 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KXX76605.1 - 0.012 15.4 0.2 0.075 12.8 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KXX76605.1 - 0.012 14.7 0.2 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KXX76605.1 - 0.013 14.9 0.1 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Gluconate_2-dh3 PF13618.1 KXX76605.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 F420_oxidored PF03807.12 KXX76605.1 - 0.083 13.3 0.1 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Patatin PF01734.17 KXX76606.1 - 1.3e-05 25.2 0.0 3.1e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Aldo_ket_red PF00248.16 KXX76608.1 - 9.9e-49 165.6 0.0 1.1e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank PF00023.25 KXX76609.1 - 1.7e-14 52.7 0.7 1.1e-06 28.0 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KXX76609.1 - 1.2e-12 47.9 0.2 0.00027 21.2 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX76609.1 - 2.4e-11 43.8 0.7 0.00098 19.5 0.3 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX76609.1 - 3.2e-10 39.8 0.5 3.1e-05 24.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KXX76609.1 - 5.9e-07 29.1 0.1 3.2e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 KXX76609.1 - 1.4e-06 27.9 0.5 1.2 9.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat MbeD_MobD PF04899.7 KXX76609.1 - 0.011 15.6 0.4 0.049 13.5 0.3 2.1 1 0 0 1 1 1 0 MbeD/MobD like NB-ARC PF00931.17 KXX76611.1 - 2.6e-12 46.2 0.0 5.1e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 KXX76611.1 - 6.2e-07 29.2 7.0 0.0012 18.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 KXX76611.1 - 3.2e-05 24.0 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 KXX76611.1 - 0.00013 21.6 0.5 1.7 8.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76611.1 - 0.0066 16.9 15.8 1.1 10.1 0.3 6.8 7 1 0 7 7 6 2 Tetratricopeptide repeat Hormone_1 PF00103.15 KXX76611.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Somatotropin hormone family RPN7 PF10602.4 KXX76611.1 - 0.023 14.1 0.1 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 KXX76611.1 - 0.027 14.8 0.2 1.5e+02 3.1 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76611.1 - 0.047 14.0 5.4 0.24 11.7 0.2 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Pox_A32 PF04665.7 KXX76611.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Arch_ATPase PF01637.13 KXX76611.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Pex19 PF04614.7 KXX76611.1 - 0.23 11.0 2.8 0.21 11.1 0.3 2.0 2 1 0 2 2 2 0 Pex19 protein family TFR_dimer PF04253.10 KXX76611.1 - 0.49 9.9 4.1 0.37 10.3 0.2 2.6 3 0 0 3 3 3 0 Transferrin receptor-like dimerisation domain TPR_16 PF13432.1 KXX76611.1 - 3.7 8.3 14.4 1.2 9.9 0.5 5.4 4 1 1 5 5 4 0 Tetratricopeptide repeat Tub_2 PF04525.7 KXX76612.1 - 1.4e-14 53.9 0.0 1.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Tubby C 2 F-box-like PF12937.2 KXX76613.1 - 6.2e-07 29.0 0.8 2.3e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 F-box-like EamA PF00892.15 KXX76614.1 - 1.4e-12 47.7 35.3 2.1e-07 31.0 12.8 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KXX76614.1 - 6.1e-07 29.6 2.6 6.1e-07 29.6 1.8 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KXX76614.1 - 0.0019 17.8 11.1 0.0019 17.8 7.7 3.1 3 1 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KXX76614.1 - 0.012 14.6 0.1 0.012 14.6 0.1 1.7 2 0 0 2 2 2 0 Nucleotide-sugar transporter Sugar_tr PF00083.19 KXX76615.1 - 1.5e-73 247.9 22.2 1.7e-73 247.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX76615.1 - 6.7e-18 64.5 28.4 1.4e-15 56.8 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX76615.1 - 0.00011 20.7 0.9 0.00011 20.7 0.6 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF1304 PF06993.7 KXX76615.1 - 1.2 8.8 7.6 0.45 10.2 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) MFS_1 PF07690.11 KXX76616.1 - 1.4e-34 119.4 17.2 1.4e-34 119.4 11.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KXX76617.1 - 2.3e-23 82.8 0.7 4.1e-11 42.5 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KXX76617.1 - 5.3e-05 22.2 0.1 0.00012 21.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX76617.1 - 0.00032 21.0 3.5 0.00048 20.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX76617.1 - 0.00041 20.3 3.1 0.00042 20.2 0.4 2.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX76617.1 - 0.0024 17.6 0.0 0.009 15.7 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX76617.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX76617.1 - 0.081 12.7 0.4 0.2 11.5 0.2 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KXX76617.1 - 0.087 11.6 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Epimerase PF01370.16 KXX76618.1 - 1.4e-17 63.9 0.0 1.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX76618.1 - 3.4e-12 45.6 0.0 4.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX76618.1 - 2.3e-09 36.5 0.0 5.1e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KXX76618.1 - 5.9e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KXX76618.1 - 2.9e-08 33.9 0.0 5.2e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KXX76618.1 - 2.2e-06 27.4 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX76618.1 - 4.8e-06 25.6 0.0 1.1e-05 24.4 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KXX76618.1 - 1.5e-05 24.2 0.1 4.3e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Saccharopine dehydrogenase NmrA PF05368.8 KXX76618.1 - 0.0018 17.5 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 KXX76618.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KXX76618.1 - 0.033 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 KXX76618.1 - 0.035 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KXX76618.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TIR PF01582.15 KXX76618.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain Metallothio_11 PF02066.10 KXX76620.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Metallothionein family 11 Mito_fiss_reg PF05308.6 KXX76620.1 - 5.1 6.3 9.7 6.9 5.9 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC_tran PF00005.22 KXX76621.1 - 1e-51 174.8 0.0 3.4e-30 105.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX76621.1 - 2.7e-43 148.3 17.0 7.2e-23 81.3 2.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 KXX76621.1 - 1.9e-09 38.1 0.0 3.4e-05 24.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 KXX76621.1 - 8.3e-09 34.9 2.8 0.0034 16.6 0.4 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KXX76621.1 - 1.4e-08 35.0 0.3 0.0013 18.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KXX76621.1 - 2.7e-06 27.0 0.1 0.035 13.5 0.0 3.5 3 1 0 4 4 4 2 AAA-like domain T2SE PF00437.15 KXX76621.1 - 3e-06 26.3 0.0 0.013 14.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KXX76621.1 - 7.3e-06 25.4 0.4 0.083 12.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX76621.1 - 7.8e-06 25.9 0.2 0.012 15.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KXX76621.1 - 9.4e-05 21.8 0.0 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX76621.1 - 0.00017 21.7 0.5 3.1 7.9 0.0 3.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KXX76621.1 - 0.00023 21.0 0.2 0.033 14.0 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KXX76621.1 - 0.00039 21.2 0.0 2.5 8.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KXX76621.1 - 0.00041 19.4 0.1 0.82 8.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KXX76621.1 - 0.0005 19.5 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF258 PF03193.11 KXX76621.1 - 0.00088 18.4 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KXX76621.1 - 0.0042 17.0 0.2 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KXX76621.1 - 0.0054 17.2 0.2 6.7 7.2 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 KXX76621.1 - 0.0065 16.7 0.7 3.7 7.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KXX76621.1 - 0.012 15.3 0.2 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 KXX76621.1 - 0.012 15.4 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KXX76621.1 - 0.014 15.0 0.3 0.91 9.3 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 KXX76621.1 - 0.018 14.0 0.7 5.5 5.8 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KXX76621.1 - 0.02 15.1 0.1 8.2 6.6 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KXX76621.1 - 0.032 13.6 0.1 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KXX76621.1 - 0.042 13.5 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 KXX76621.1 - 0.072 11.7 2.0 5.8 5.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 KXX76621.1 - 0.076 12.8 0.4 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 KXX76621.1 - 0.088 12.9 0.2 24 5.1 0.0 3.2 3 0 0 3 3 2 0 RNA helicase cobW PF02492.14 KXX76621.1 - 0.17 11.2 1.2 1.2 8.5 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KXX76621.1 - 0.22 10.7 0.2 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NB-ARC PF00931.17 KXX76621.1 - 0.22 10.3 0.7 0.58 8.9 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KXX76621.1 - 0.75 9.3 7.9 6.3 6.3 0.1 3.8 4 0 0 4 4 3 0 AAA domain SecY PF00344.15 KXX76622.1 - 2.2e-96 322.8 11.0 2.8e-96 322.4 7.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KXX76622.1 - 1.1e-18 66.4 0.2 7.2e-18 63.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 KXX76622.1 - 1.9 8.0 4.2 0.84 9.1 0.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC RhoGAP PF00620.22 KXX76623.1 - 1.1e-10 41.3 0.0 1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain AAA_33 PF13671.1 KXX76624.1 - 2.1e-13 50.3 0.2 2.9e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX76624.1 - 3.2e-09 37.6 0.0 5.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KXX76624.1 - 8.9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 KXX76624.1 - 5.7e-08 33.1 0.1 1.3e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KXX76624.1 - 3.9e-05 23.6 0.3 0.00019 21.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KXX76624.1 - 0.00026 21.2 0.2 0.00066 19.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KXX76624.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KXX76624.1 - 0.0027 18.0 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KXX76624.1 - 0.0062 15.2 0.0 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 KXX76624.1 - 0.009 15.6 0.1 0.018 14.6 0.1 1.5 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KXX76624.1 - 0.01 15.8 0.6 0.028 14.3 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KXX76624.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Cytidylate_kin2 PF13189.1 KXX76624.1 - 0.018 14.9 0.1 0.042 13.7 0.1 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family ABC_tran PF00005.22 KXX76624.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.15 KXX76624.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase IPT PF01745.11 KXX76624.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_22 PF13401.1 KXX76624.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX76624.1 - 0.036 13.4 0.2 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX76624.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Tubulin PF00091.20 KXX76624.1 - 0.074 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Parvo_NS1 PF01057.12 KXX76624.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.6 KXX76624.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.9 1 1 0 1 1 1 0 tRNA ligase kinase domain PRK PF00485.13 KXX76624.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 KXX76624.1 - 0.16 11.6 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase Aminotran_5 PF00266.14 KXX76625.1 - 2.1e-20 72.7 0.0 9.2e-20 70.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M54 PF07998.6 KXX76626.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_2 PF13574.1 KXX76626.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fungal_trans PF04082.13 KXX76627.1 - 1.2e-23 83.3 0.0 4.1e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX76627.1 - 3.5e-09 36.4 9.2 5.8e-09 35.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.15 KXX76628.1 - 1.8e-67 227.8 0.0 1.3e-40 139.2 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KXX76628.1 - 7.3e-23 81.1 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.12 KXX76629.1 - 4.2e-53 179.9 0.3 6.8e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 KXX76629.1 - 8.8e-07 28.8 0.3 1.5e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.11 KXX76629.1 - 7e-06 25.3 0.1 1.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 KXX76629.1 - 3.9e-05 24.4 3.0 8.4e-05 23.3 0.7 2.8 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 KXX76629.1 - 0.00011 22.3 0.5 0.00019 21.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ring_hydroxyl_A PF00848.14 KXX76629.1 - 0.00046 19.9 0.2 0.23 11.1 0.2 2.3 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) AAA_18 PF13238.1 KXX76629.1 - 0.00062 20.0 0.9 0.017 15.4 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX76629.1 - 0.0015 18.4 0.3 0.037 13.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KXX76629.1 - 0.0083 16.2 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KXX76629.1 - 0.023 14.3 0.1 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KXX76629.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KXX76629.1 - 0.041 14.0 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX76629.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsbRD_N PF14361.1 KXX76629.1 - 0.066 13.6 0.9 1.2 9.6 0.0 3.0 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain ETF PF01012.16 KXX76629.1 - 0.069 12.8 0.1 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain zf-C2H2_4 PF13894.1 KXX76629.1 - 0.072 13.4 0.5 0.18 12.1 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger IstB_IS21 PF01695.12 KXX76629.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-U1 PF06220.7 KXX76629.1 - 0.098 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger Adeno_IVa2 PF02456.10 KXX76629.1 - 0.12 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Hpr_kinase_C PF07475.7 KXX76629.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain zf-C2H2_2 PF12756.2 KXX76629.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpb4 PF03874.11 KXX76629.1 - 0.17 11.8 1.2 1.4 8.9 0.8 2.5 1 1 0 1 1 1 0 RNA polymerase Rpb4 AAA_23 PF13476.1 KXX76629.1 - 2.1 8.6 4.3 2.1 8.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain Glyco_hydro_26 PF02156.10 KXX76630.1 - 1.8e-92 310.1 3.9 2.2e-92 309.8 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DUF1888 PF08985.6 KXX76630.1 - 0.023 14.3 0.3 0.056 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1888) Glycoprotein PF03409.10 KXX76630.1 - 0.027 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Endotoxin_C PF03944.9 KXX76630.1 - 0.14 12.2 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 delta endotoxin GMC_oxred_N PF00732.14 KXX76631.1 - 3.7e-59 200.3 0.0 2.1e-58 197.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX76631.1 - 4.2e-36 124.3 0.0 6.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX76631.1 - 8.6e-06 24.8 3.3 0.0033 16.3 1.7 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX76631.1 - 1.8e-05 23.8 1.3 0.00014 20.8 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX76631.1 - 0.0002 20.4 0.8 0.00048 19.1 0.7 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX76631.1 - 0.0016 18.4 1.3 0.0046 16.9 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX76631.1 - 0.0051 16.9 1.0 0.54 10.2 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX76631.1 - 0.0094 15.0 0.1 0.027 13.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KXX76631.1 - 0.039 13.8 0.5 0.11 12.3 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX76631.1 - 0.13 11.9 1.4 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KXX76631.1 - 0.42 9.0 1.2 0.69 8.3 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.2 KXX76632.1 - 0.00093 18.8 0.1 0.0022 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3786 PF12654.2 KXX76632.1 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3786) F-box PF00646.28 KXX76632.1 - 0.0054 16.3 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain FAD_binding_4 PF01565.18 KXX76634.1 - 4e-18 65.2 1.9 5.1e-18 64.8 0.6 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 KXX76634.1 - 6e-12 45.2 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TAT_signal PF10518.4 KXX76634.1 - 5.2 7.3 8.1 15 5.8 0.6 3.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Transp_cyt_pur PF02133.10 KXX76635.1 - 2e-09 36.5 42.3 2.5e-09 36.1 24.6 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin His_Phos_2 PF00328.17 KXX76636.1 - 3.1e-17 62.9 0.2 2.5e-15 56.6 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3377 PF11857.3 KXX76636.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) C1_2 PF03107.11 KXX76637.1 - 0.087 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 C1 domain BTB PF00651.26 KXX76638.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Hap4_Hap_bind PF10297.4 KXX76640.1 - 6.8e-09 35.2 7.1 6.8e-09 35.2 4.9 3.0 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KXX76640.1 - 0.0001 22.1 15.7 0.00053 19.8 5.9 2.4 1 1 1 2 2 2 2 bZIP transcription factor CASP_C PF08172.7 KXX76640.1 - 0.0081 15.2 0.1 0.014 14.3 0.1 1.4 1 0 0 1 1 1 1 CASP C terminal bZIP_Maf PF03131.12 KXX76640.1 - 0.087 13.1 8.3 0.15 12.3 5.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2397 PF09660.5 KXX76640.1 - 0.14 10.7 4.6 0.22 10.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Fmp27_WPPW PF10359.4 KXX76640.1 - 0.45 8.8 2.5 0.64 8.3 1.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BBP1_C PF15272.1 KXX76640.1 - 0.61 9.6 3.1 0.98 8.9 2.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Cortex-I_coil PF09304.5 KXX76640.1 - 0.84 9.7 8.3 1.8 8.6 5.8 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil TFIIA PF03153.8 KXX76640.1 - 1.1 9.1 6.8 1.9 8.2 4.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.10 KXX76640.1 - 1.1 9.1 15.4 4.9 7.0 0.3 2.4 1 1 1 2 2 2 0 Basic region leucine zipper TEX13 PF15186.1 KXX76640.1 - 1.5 8.3 5.8 2.5 7.6 4.0 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family IncA PF04156.9 KXX76640.1 - 8.5 5.9 8.5 16 5.0 5.9 1.3 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 KXX76641.1 - 1.5e-24 86.3 0.1 2.9e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 KXX76641.1 - 9.7e-06 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KXX76641.1 - 7.9e-05 22.4 0.1 0.00026 20.7 0.0 2.0 2 1 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 KXX76641.1 - 0.03 12.7 0.1 0.047 12.1 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family DUF2450 PF10475.4 KXX76641.1 - 0.045 12.6 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 KXX76641.1 - 0.078 12.5 2.6 0.23 11.0 0.3 2.1 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 KXX76641.1 - 0.15 12.3 0.3 1.4 9.1 0.0 2.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_L1 PF00687.16 KXX76642.1 - 2.9e-21 75.8 0.0 3.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 KXX76643.1 - 1.4e-100 335.9 0.1 1.9e-100 335.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KXX76643.1 - 4.1e-41 140.5 0.1 1e-40 139.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KXX76643.1 - 0.0011 18.1 0.2 0.0024 17.0 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Choline_transpo PF04515.7 KXX76644.1 - 3.2e-104 348.2 17.7 3.2e-104 348.2 12.3 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Cyto_ox_2 PF02322.10 KXX76644.1 - 0.00097 18.3 10.2 0.00097 18.3 7.1 3.7 3 1 0 4 4 4 2 Cytochrome oxidase subunit II DUF4191 PF13829.1 KXX76644.1 - 0.11 11.5 5.4 0.044 12.9 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) IspA PF04279.10 KXX76644.1 - 1 9.3 20.6 0.2 11.6 10.2 2.6 2 1 0 2 2 2 0 Intracellular septation protein A Dynamin_N PF00350.18 KXX76645.1 - 1.3e-10 41.3 0.0 4.9e-10 39.4 0.0 2.0 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.22 KXX76645.1 - 8.7e-06 26.0 0.0 0.00052 20.3 0.0 2.9 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 KXX76645.1 - 1e-05 25.4 0.0 0.0021 18.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX76645.1 - 3.1e-05 23.2 0.0 0.00037 19.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX76645.1 - 0.00031 20.8 0.0 0.00031 20.8 0.0 4.0 6 0 0 6 6 6 1 AAA ATPase domain Miro PF08477.8 KXX76645.1 - 0.0026 18.2 0.0 0.026 15.0 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 KXX76645.1 - 0.0087 16.2 0.5 0.33 11.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain AIG1 PF04548.11 KXX76645.1 - 0.026 13.6 0.5 0.32 10.0 0.0 2.5 2 1 1 3 3 3 0 AIG1 family AAA_10 PF12846.2 KXX76645.1 - 0.059 12.8 0.8 1.3 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain DUF919 PF06034.6 KXX76645.1 - 0.09 12.4 0.6 0.3 10.7 0.4 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) FeoB_N PF02421.13 KXX76645.1 - 0.1 11.8 0.0 10 5.3 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.17 KXX76645.1 - 0.11 11.2 0.0 4.7 5.9 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_29 PF13555.1 KXX76645.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KXX76645.1 - 0.13 11.2 0.0 0.64 8.9 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Sec8_exocyst PF04048.9 KXX76645.1 - 0.15 11.7 2.5 10 5.7 0.2 3.4 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain B3_4 PF03483.12 KXX76646.1 - 3.8e-25 88.3 0.0 6.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KXX76646.1 - 9.7e-15 54.1 0.0 1.2e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 KXX76646.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Ank_2 PF12796.2 KXX76648.1 - 7.9e-61 202.4 0.1 1.3e-23 83.1 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX76648.1 - 3.9e-51 168.4 2.3 5.2e-09 35.4 0.0 9.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 KXX76648.1 - 2.2e-37 126.7 0.7 1.1e-09 38.5 0.1 7.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX76648.1 - 7.4e-36 118.6 0.2 1.8e-06 27.6 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KXX76648.1 - 1.2e-34 117.5 2.0 6.7e-10 38.8 0.1 7.1 4 3 4 8 8 8 6 Ankyrin repeats (many copies) NACHT PF05729.7 KXX76648.1 - 6.7e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX76648.1 - 0.00011 22.2 0.1 0.00039 20.4 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.15 KXX76648.1 - 0.0022 16.9 0.0 0.0046 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KXX76648.1 - 0.0074 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RICH PF05062.7 KXX76648.1 - 0.026 14.6 0.6 0.055 13.5 0.4 1.6 1 0 0 1 1 1 0 RICH domain RNA_helicase PF00910.17 KXX76648.1 - 0.061 13.5 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF4423 PF14394.1 KXX76648.1 - 0.09 12.3 0.3 3.3 7.2 0.0 3.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4423) B-block_TFIIIC PF04182.7 KXX76648.1 - 0.12 12.2 0.0 23 4.9 0.0 2.7 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC NACHT PF05729.7 KXX76649.1 - 0.00023 20.8 0.0 0.00064 19.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX76649.1 - 0.0039 17.3 0.0 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 KXX76649.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_16 PF13191.1 KXX76649.1 - 0.073 13.0 0.0 0.43 10.5 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain Bacillus_HBL PF05791.6 KXX76650.1 - 0.48 9.7 20.0 0.18 11.1 3.0 3.7 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 KXX76650.1 - 0.67 9.0 8.0 0.77 8.8 0.4 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein HET PF06985.6 KXX76651.1 - 1.4e-16 60.9 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4360 PF14273.1 KXX76652.1 - 3.7e-37 127.7 0.1 4.2e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.11 KXX76653.1 - 1.8e-35 122.3 50.7 1.8e-35 122.3 35.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX76653.1 - 7e-12 44.3 23.2 2e-11 42.8 16.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glycophorin_A PF01102.13 KXX76653.1 - 0.32 10.7 1.9 20 4.9 0.0 3.1 3 0 0 3 3 3 0 Glycophorin A Peptidase_U4 PF03419.8 KXX76653.1 - 0.99 8.4 9.0 0.071 12.1 2.3 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Romo1 PF10247.4 KXX76655.1 - 9.4e-30 102.6 12.7 1.2e-29 102.2 8.8 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Spore_YabQ PF09578.5 KXX76655.1 - 0.42 10.5 3.8 0.69 9.9 0.5 2.0 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Cu-oxidase_3 PF07732.10 KXX76656.1 - 2.8e-43 146.3 5.8 2.6e-40 136.8 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KXX76656.1 - 2.8e-33 115.0 0.2 6.6e-31 107.3 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX76656.1 - 3.8e-30 104.2 8.7 5.6e-30 103.6 2.9 3.2 4 0 0 4 4 4 1 Multicopper oxidase FHA PF00498.21 KXX76658.1 - 5.3e-17 61.6 0.0 1.2e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Uds1 PF15456.1 KXX76658.1 - 0.004 17.1 0.6 0.004 17.1 0.4 2.6 1 1 2 3 3 3 1 Up-regulated During Septation IncA PF04156.9 KXX76658.1 - 5.1 6.6 9.0 8.4 5.9 0.6 3.1 3 0 0 3 3 3 0 IncA protein SDA1 PF05285.7 KXX76659.1 - 0.014 14.6 2.3 0.02 14.1 1.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KXX76659.1 - 0.048 11.5 3.2 0.062 11.2 2.2 1.2 1 0 0 1 1 1 0 Nop14-like family Podoplanin PF05808.6 KXX76659.1 - 0.094 12.2 4.4 0.36 10.3 3.1 1.9 1 1 0 1 1 1 0 Podoplanin BUD22 PF09073.5 KXX76659.1 - 0.17 10.9 3.4 0.24 10.4 2.3 1.2 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 KXX76659.1 - 3.8 6.1 4.9 5.6 5.6 3.4 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 KXX76659.1 - 7.4 5.1 14.7 1 8.0 7.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 KXX76660.1 - 4.5 7.7 19.7 0.81 10.1 6.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein MFS_1 PF07690.11 KXX76661.1 - 2.1e-37 128.6 53.6 2.4e-36 125.2 36.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 KXX76662.1 - 2.1e-23 82.8 0.3 2.8e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX76662.1 - 6.3e-15 55.6 2.6 8.9e-15 55.1 1.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX76662.1 - 0.0022 17.4 0.2 0.0055 16.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KXX76662.1 - 0.0055 15.7 0.8 0.0085 15.1 0.3 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KXX76662.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 KXX76662.1 - 0.025 13.4 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein NAD_binding_2 PF03446.10 KXX76662.1 - 0.026 14.3 0.1 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SIR2 PF02146.12 KXX76663.1 - 4.1e-54 182.9 0.0 6.3e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family GST_N_3 PF13417.1 KXX76663.1 - 3.2e-26 91.3 0.0 7.1e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX76663.1 - 8.5e-18 64.1 0.0 2.7e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX76663.1 - 2.8e-07 30.3 0.2 9.6e-07 28.6 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX76663.1 - 3.8e-07 30.1 0.0 1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX76663.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CENP-Q PF13094.1 KXX76663.1 - 0.05 13.6 4.1 0.086 12.8 2.9 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GST_C_3 PF14497.1 KXX76663.1 - 0.099 13.1 3.6 0.26 11.8 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PCI PF01399.22 KXX76664.1 - 2.1e-19 69.8 0.3 1.4e-18 67.1 0.0 2.5 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KXX76664.1 - 1.3e-06 28.1 0.1 3.7e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Pkinase_Tyr PF07714.12 KXX76664.1 - 0.017 14.1 0.1 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_10 PF13374.1 KXX76664.1 - 0.03 14.2 1.3 7.2 6.6 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX76664.1 - 0.33 10.6 3.0 3 7.6 0.5 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76664.1 - 0.34 10.8 5.3 3.5 7.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX76664.1 - 0.61 10.0 5.9 1.3 9.0 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX76664.1 - 2.1 8.4 6.5 0.94 9.5 0.4 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat CWC25 PF12542.3 KXX76665.1 - 1.6e-28 99.0 2.3 1.6e-28 99.0 1.6 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 KXX76665.1 - 7.8e-10 38.6 2.5 7.8e-10 38.6 1.7 2.7 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Thioredoxin PF00085.15 KXX76666.1 - 3.1e-28 97.4 0.0 4.2e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX76666.1 - 7.1e-08 32.4 0.0 1.3e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KXX76666.1 - 5.1e-07 29.8 0.1 1.6e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KXX76666.1 - 0.00036 20.2 0.1 0.37 10.4 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 KXX76666.1 - 0.00038 20.4 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KXX76666.1 - 0.00065 19.2 0.1 0.76 9.3 0.0 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KXX76666.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 KXX76666.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Rsm22 PF09243.5 KXX76667.1 - 8.7e-30 103.6 0.0 1.2e-28 99.9 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 KXX76667.1 - 0.0013 18.5 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76667.1 - 0.048 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76667.1 - 0.13 12.8 0.0 1.1 9.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KXX76668.1 - 6.6e-18 64.5 0.4 1.1e-17 63.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KXX76668.1 - 1.3e-08 34.6 10.4 0.0009 19.4 1.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KXX76668.1 - 1.1e-07 31.6 8.5 2.7e-07 30.3 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KXX76668.1 - 0.0024 18.0 7.9 0.013 15.7 0.8 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KXX76668.1 - 0.013 15.1 1.3 0.013 15.1 0.9 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KXX76668.1 - 0.015 15.5 7.8 0.041 14.1 1.3 3.1 2 0 0 2 2 2 0 Zinc-finger double domain 4HBT PF03061.17 KXX76669.1 - 6.8e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Hamartin PF04388.7 KXX76669.1 - 0.11 11.1 1.8 0.15 10.6 1.3 1.1 1 0 0 1 1 1 0 Hamartin protein TP_methylase PF00590.15 KXX76670.1 - 1.7e-44 152.0 0.0 3.5e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 KXX76670.1 - 8e-05 21.8 0.0 0.00028 20.1 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Biotin_lipoyl PF00364.17 KXX76671.1 - 4e-16 58.3 0.4 7.6e-16 57.5 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KXX76671.1 - 5e-08 32.4 0.4 0.01 15.5 0.0 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD PF00529.15 KXX76671.1 - 6.4e-05 22.4 9.5 0.0074 15.6 0.0 3.2 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 KXX76671.1 - 0.00035 20.8 0.0 0.66 10.3 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein Nairovirus_M PF07948.6 KXX76671.1 - 0.019 13.1 0.0 0.026 12.6 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like HlyD_2 PF12700.2 KXX76671.1 - 0.16 11.1 1.0 5.2 6.1 0.0 2.6 2 1 1 3 3 3 0 HlyD family secretion protein NAD_binding_7 PF13241.1 KXX76672.1 - 1.6e-09 37.8 0.0 2.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 KXX76672.1 - 3.7e-05 22.6 0.0 7.6e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Ras PF00071.17 KXX76673.1 - 5e-54 182.0 0.0 5.8e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX76673.1 - 3.8e-16 59.6 0.0 5.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX76673.1 - 2.4e-09 36.6 0.0 4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX76673.1 - 0.0012 18.0 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KXX76673.1 - 0.0046 16.1 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KXX76673.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KXX76673.1 - 0.015 13.9 0.0 0.032 12.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 KXX76673.1 - 0.097 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KXX76673.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase BPL_LplA_LipB PF03099.14 KXX76674.1 - 6.3e-07 29.4 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.4 KXX76675.1 - 1.4e-66 224.3 0.0 1.8e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PLRV_ORF5 PF01690.12 KXX76675.1 - 0.073 12.2 21.0 0.12 11.5 14.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Methyltrn_RNA_3 PF02598.12 KXX76676.1 - 3.1e-85 286.0 0.0 3.5e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 KXX76676.1 - 0.0013 18.6 0.0 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family Pap_E4 PF02711.9 KXX76676.1 - 0.092 13.5 1.1 0.58 11.0 0.9 2.1 2 0 0 2 2 2 0 E4 protein Cut8_N PF14482.1 KXX76676.1 - 0.13 12.2 0.6 0.28 11.1 0.4 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Mpv17_PMP22 PF04117.7 KXX76677.1 - 6e-15 54.6 5.3 7.1e-15 54.3 0.3 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family Kelch_4 PF13418.1 KXX76678.1 - 2.7e-39 132.6 8.2 2.1e-07 30.5 0.7 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX76678.1 - 5.9e-36 121.8 3.9 4e-09 36.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KXX76678.1 - 4.7e-34 115.6 1.4 3e-11 42.6 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KXX76678.1 - 5.9e-33 111.6 5.3 9.8e-13 47.6 0.4 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KXX76678.1 - 8.1e-32 108.6 13.9 5e-08 32.8 0.1 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX76678.1 - 6e-20 70.1 8.5 3e-07 29.9 0.3 6.7 6 1 0 6 6 6 5 Kelch motif Filament PF00038.16 KXX76678.1 - 1.1e-05 25.1 31.0 1.1e-05 25.1 21.5 4.2 1 1 1 3 3 3 2 Intermediate filament protein RAG2 PF03089.9 KXX76678.1 - 0.11 11.1 0.2 2.4 6.7 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 Ribosomal_S27e PF01667.12 KXX76679.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KXX76679.1 - 0.011 15.5 1.4 0.013 15.3 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 KXX76679.1 - 0.29 10.4 3.3 0.41 10.0 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding RNR_inhib PF08591.5 KXX76680.1 - 1.5e-21 77.0 1.3 4.8e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Raptor_N PF14538.1 KXX76681.1 - 7.6e-63 210.9 0.0 1.6e-62 209.9 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KXX76681.1 - 5.1e-09 35.6 0.7 1.2 9.1 0.0 6.3 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KXX76681.1 - 0.00036 20.2 1.4 0.031 14.0 0.1 2.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 KXX76681.1 - 0.00071 19.4 0.7 4.2 7.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Atx10homo_assoc PF09759.4 KXX76681.1 - 0.018 14.8 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF1900 PF08954.6 KXX76681.1 - 0.18 11.3 0.0 12 5.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1900) Phosducin PF02114.11 KXX76682.1 - 1.9e-13 49.7 0.0 2.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KXX76682.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF3503 PF12011.3 KXX76682.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) HNH_2 PF13391.1 KXX76683.1 - 7.1e-13 48.1 0.2 3.2e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease SIP1 PF04938.7 KXX76685.1 - 4e-06 26.3 0.0 0.009 15.3 0.0 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.15 KXX76686.1 - 8.5e-74 248.3 0.0 1.1e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KXX76686.1 - 4.8e-05 23.1 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 KXX76686.1 - 0.76 8.4 7.6 1.1 7.8 5.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Borrelia_P83 PF05262.6 KXX76686.1 - 3 6.0 7.0 4.3 5.4 4.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1620 PF07774.8 KXX76687.1 - 1.2e-71 240.3 0.0 2.1e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KXX76687.1 - 3.4e-15 56.1 6.1 9.1e-12 44.9 1.8 2.8 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KXX76687.1 - 9.8e-07 28.0 1.0 0.071 12.6 0.0 5.4 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.1 KXX76687.1 - 0.16 12.3 3.0 3.7 7.9 0.0 3.7 2 0 0 2 2 2 0 PQQ-like domain LRR_4 PF12799.2 KXX76688.1 - 2e-07 30.4 0.3 4.9e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX76688.1 - 1.9e-06 27.4 1.0 4.2e-06 26.4 0.7 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KXX76688.1 - 0.00031 20.3 1.0 0.042 13.8 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 KXX76688.1 - 0.0041 17.0 0.8 0.39 11.1 0.0 3.0 2 0 0 2 2 2 1 Leucine rich repeat adh_short PF00106.20 KXX76689.1 - 7.4e-22 78.0 0.1 5.2e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KXX76689.1 - 5.7e-10 39.1 0.1 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KXX76689.1 - 0.00049 19.9 0.0 0.034 13.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Med17 PF10156.4 KXX76691.1 - 9.7e-80 268.1 0.0 1.2e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 KXX76692.1 - 7.5e-162 536.9 0.8 2.3e-119 397.5 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase YIF1 PF03878.10 KXX76693.1 - 1.7e-73 246.6 0.9 2.1e-73 246.4 0.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KXX76693.1 - 0.00017 21.1 5.5 0.00017 21.1 3.8 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 KXX76694.1 - 4.1e-77 259.3 0.0 5.8e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KXX76694.1 - 9.1e-52 175.3 0.2 1.6e-51 174.5 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KXX76694.1 - 4.4e-07 29.9 0.2 2.1e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KXX76694.1 - 4.9e-06 25.5 0.0 1.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 KXX76694.1 - 0.0047 16.6 0.2 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KXX76694.1 - 0.008 15.7 0.2 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KXX76694.1 - 0.0095 15.3 0.1 0.029 13.7 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KXX76694.1 - 0.011 15.6 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KXX76694.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 KXX76694.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KXX76694.1 - 0.034 14.0 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KXX76694.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 KXX76694.1 - 0.071 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PI3_PI4_kinase PF00454.22 KXX76695.1 - 7.2e-50 169.6 0.0 1.4e-49 168.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KXX76695.1 - 9e-48 163.0 1.8 1.3e-47 162.4 0.6 1.8 2 0 0 2 2 2 1 FAT domain UME PF08064.8 KXX76695.1 - 7.9e-30 102.9 0.1 1.8e-28 98.5 0.0 3.3 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 KXX76695.1 - 4.6e-17 61.1 0.0 1.3e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_16 PF13432.1 KXX76695.1 - 0.00018 22.0 2.1 1.3 9.7 0.0 3.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76695.1 - 0.0023 18.4 5.1 0.24 12.1 0.1 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76695.1 - 0.008 16.4 1.6 0.4 11.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KXX76695.1 - 0.11 12.6 0.9 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation zf-PARP PF00645.13 KXX76696.1 - 4.8e-21 74.7 0.3 1e-20 73.7 0.2 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Trypan_PARP PF05887.6 KXX76696.1 - 1.8 8.3 89.3 0.12 12.2 18.4 3.6 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 KXX76698.1 - 1.2e-70 237.6 0.0 1.7e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76698.1 - 5.3e-31 107.6 0.0 7.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KXX76698.1 - 2.3e-14 53.6 1.5 8.7e-14 51.7 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KXX76698.1 - 4.3e-09 35.7 0.0 7.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KXX76698.1 - 6.9e-05 22.6 0.0 0.00025 20.8 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 KXX76698.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KXX76698.1 - 0.049 12.9 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KXX76698.1 - 0.051 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX76698.1 - 0.082 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fe_hyd_lg_C PF02906.9 KXX76699.1 - 2e-60 204.4 0.0 4.6e-60 203.3 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF3606 PF12244.3 KXX76699.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) SUZ PF12752.2 KXX76700.1 - 3.4e-05 24.2 6.1 3.4e-05 24.2 4.3 4.0 4 1 0 4 4 4 1 SUZ domain ARGLU PF15346.1 KXX76700.1 - 0.43 10.3 16.0 0.23 11.2 6.4 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 API5 PF05918.6 KXX76700.1 - 2.2 6.6 5.6 3 6.2 3.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-H2C2_2 PF13465.1 KXX76701.1 - 1.2e-07 31.7 8.4 3.4e-06 27.0 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX76701.1 - 1.1e-05 25.4 3.2 0.00058 19.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX76701.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KXX76701.1 - 0.17 12.0 2.3 4.2 7.6 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.1 KXX76704.1 - 2.3e-12 45.6 4.6 0.16 12.1 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KXX76704.1 - 1.4e-10 40.5 7.0 0.00043 19.8 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KXX76704.1 - 8.4e-05 22.0 7.9 6.2 7.2 0.0 5.9 6 1 1 7 7 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KXX76704.1 - 0.00026 20.6 3.3 22 5.8 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 KXX76704.1 - 0.0013 18.4 12.3 1.1 9.0 0.1 4.8 3 2 1 4 4 4 3 Leucine rich repeat SDA1 PF05285.7 KXX76704.1 - 0.25 10.5 19.3 0.33 10.1 13.4 1.2 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 KXX76704.1 - 1.4 8.4 18.4 3 7.3 12.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin SprA-related PF12118.3 KXX76704.1 - 3 7.0 14.5 4.6 6.4 10.0 1.2 1 0 0 1 1 1 0 SprA-related family Usp PF00582.21 KXX76704.1 - 4.6 7.4 10.9 10 6.2 7.6 1.6 1 0 0 1 1 1 0 Universal stress protein family RRN3 PF05327.6 KXX76704.1 - 4.8 5.1 13.2 6.6 4.7 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 KXX76704.1 - 6.1 4.9 17.6 8.8 4.4 12.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 KXX76704.1 - 7.2 4.5 15.6 11 3.9 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 KXX76704.1 - 7.5 6.2 13.8 14 5.4 9.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Dus PF01207.12 KXX76705.1 - 2.6e-07 29.7 0.0 0.00074 18.4 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Mei5 PF10376.4 KXX76706.1 - 0.17 11.4 4.3 0.94 8.9 0.0 2.2 1 1 0 2 2 2 0 Double-strand recombination repair protein UPF0697 PF15117.1 KXX76706.1 - 4.9 6.9 5.5 7.9 6.3 3.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 Trypan_PARP PF05887.6 KXX76706.1 - 5.7 6.7 8.9 2.9 7.7 1.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pol_alpha_B_N PF08418.5 KXX76707.1 - 0.077 12.5 1.0 0.15 11.5 0.7 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_18 PF00704.23 KXX76708.1 - 3.7e-93 312.7 2.6 5.1e-93 312.2 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3153 PF11353.3 KXX76708.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Proteasome PF00227.21 KXX76709.1 - 2.1e-45 154.3 0.1 2.7e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KXX76709.1 - 2e-13 49.3 0.5 4.4e-13 48.2 0.4 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Orbi_NS3 PF01616.11 KXX76710.1 - 0.57 9.1 5.7 1.2 8.0 3.9 1.5 1 0 0 1 1 1 0 Orbivirus NS3 IncA PF04156.9 KXX76710.1 - 9.3 5.7 31.4 2.5 7.6 10.0 2.6 2 0 0 2 2 2 0 IncA protein Cmc1 PF08583.5 KXX76711.1 - 0.00085 19.0 0.7 0.0047 16.6 0.5 2.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Med15 PF09606.5 KXX76711.1 - 0.0044 15.3 23.6 0.0056 14.9 16.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KXX76711.1 - 0.0058 14.9 23.1 0.01 14.1 16.0 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KXX76711.1 - 0.015 15.3 13.6 0.026 14.5 9.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gag_spuma PF03276.9 KXX76711.1 - 0.16 10.2 17.6 0.22 9.7 12.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 KXX76711.1 - 0.25 11.2 18.9 0.0084 16.0 8.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 KXX76711.1 - 4.2 7.0 19.8 0.97 9.1 11.5 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AMPKBI PF04739.10 KXX76711.1 - 5.6 6.8 9.4 12 5.8 6.5 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Band_3_cyto PF07565.8 KXX76711.1 - 9.8 5.6 10.3 0.73 9.2 3.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain ER_lumen_recept PF00810.13 KXX76713.1 - 8.9e-40 136.5 9.3 1.3e-39 136.0 6.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2227 PF09988.4 KXX76713.1 - 0.017 14.7 1.1 0.037 13.6 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.9 KXX76713.1 - 0.065 12.8 0.0 0.065 12.8 0.0 3.3 4 0 0 4 4 4 0 PQ loop repeat ATP_sub_h PF10775.4 KXX76714.1 - 5.2e-25 86.9 0.5 8.2e-25 86.3 0.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KXX76714.1 - 0.055 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DOMON PF03351.12 KXX76715.1 - 5e-08 32.9 0.2 2.3e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 KXX76715.1 - 0.00098 18.6 5.6 0.00098 18.6 3.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1627 PF07789.7 KXX76716.1 - 7.4 6.1 9.8 1.5 8.3 3.9 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1627) AIRC PF00731.15 KXX76717.1 - 5.9e-60 200.8 0.2 1.2e-59 199.9 0.2 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KXX76717.1 - 2.6e-48 163.6 0.0 5.1e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KXX76717.1 - 2.1e-11 43.9 0.0 5.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KXX76717.1 - 2.1e-05 23.9 0.0 6.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KXX76717.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 KXX76717.1 - 0.0078 15.5 0.0 0.04 13.2 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.1 KXX76717.1 - 0.0079 16.5 0.0 0.52 10.6 0.0 2.8 3 0 0 3 3 3 1 XdhC Rossmann domain Fer2_3 PF13085.1 KXX76718.1 - 4.5e-33 113.3 0.0 7.2e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KXX76718.1 - 3e-09 37.0 6.2 3e-09 37.0 4.3 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KXX76718.1 - 3.8e-09 36.4 4.4 3.8e-09 36.4 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KXX76718.1 - 6.2e-05 23.3 1.3 6.2e-05 23.3 0.9 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KXX76718.1 - 0.00015 21.4 3.7 0.00015 21.4 2.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KXX76718.1 - 0.00021 21.5 4.1 0.031 14.5 0.5 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KXX76718.1 - 0.0033 17.1 0.2 0.0033 17.1 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KXX76718.1 - 0.027 14.8 5.8 0.027 14.8 4.0 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KXX76718.1 - 0.045 14.1 1.0 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KXX76718.1 - 1.2 9.8 5.4 0.98 10.0 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain WD40 PF00400.27 KXX76720.1 - 1.1e-50 167.7 18.9 2.5e-10 39.8 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KXX76720.1 - 1.6e-15 56.0 3.0 2.7e-15 55.3 2.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 KXX76720.1 - 0.0027 17.4 0.0 1.4 8.6 0.0 3.6 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KXX76720.1 - 0.0033 16.5 0.0 0.7 8.9 0.0 2.4 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KXX76720.1 - 0.078 11.2 0.4 4.8 5.3 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.3 KXX76720.1 - 0.15 10.1 0.3 4 5.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_60s PF00428.14 KXX76720.1 - 3.8 7.9 10.2 10 6.5 7.1 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 KXX76721.1 - 7.3e-64 215.4 0.0 9.1e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76721.1 - 1.4e-28 99.7 0.0 1.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KXX76721.1 - 0.008 16.6 1.7 0.0083 16.6 0.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KXX76721.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 KXX76721.1 - 0.033 13.9 0.1 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyclin_N PF00134.18 KXX76722.1 - 7.1e-11 41.7 0.1 1.2e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain CDC45 PF02724.9 KXX76723.1 - 2.4 6.0 5.9 3.1 5.7 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1675 PF07897.6 KXX76723.1 - 5.3 6.8 7.2 0.86 9.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF3269 PF11673.3 KXX76724.1 - 0.044 14.2 0.1 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Pkinase PF00069.20 KXX76725.1 - 1.2e-30 106.5 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76725.1 - 7.1e-10 38.3 0.0 1.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2009 PF09418.5 KXX76726.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Mito_fiss_reg PF05308.6 KXX76732.1 - 0.1 11.9 7.0 0.16 11.2 4.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KXX76732.1 - 2.4 7.3 7.6 3.9 6.6 5.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_23 PF13489.1 KXX76733.1 - 4e-20 72.1 0.0 5.2e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76733.1 - 2.1e-13 50.8 0.1 4.3e-12 46.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76733.1 - 2.6e-13 49.8 0.0 1.7e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76733.1 - 4e-11 43.2 0.0 3.5e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX76733.1 - 3.7e-10 40.1 0.0 7.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KXX76733.1 - 2.1e-05 23.7 0.0 3.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KXX76733.1 - 0.00019 20.5 0.0 0.00074 18.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KXX76733.1 - 0.00022 21.5 0.0 0.0005 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX76733.1 - 0.0013 18.7 0.0 0.0056 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX76733.1 - 0.0019 17.6 0.0 0.0049 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KXX76733.1 - 0.0022 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KXX76733.1 - 0.0042 16.2 0.0 2 7.4 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KXX76733.1 - 0.028 13.6 0.0 0.065 12.4 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_16 PF10294.4 KXX76733.1 - 0.048 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Dicty_REP PF05086.7 KXX76734.1 - 9.4 3.8 10.6 10 3.7 7.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.11 KXX76735.1 - 1.7e-21 76.3 28.7 1.7e-21 76.3 19.9 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily AKAP2_C PF15304.1 KXX76736.1 - 0.0017 18.0 1.8 0.0017 18.0 1.2 3.1 2 1 0 3 3 3 1 A-kinase anchor protein 2 C-terminus DUF4140 PF13600.1 KXX76736.1 - 8 6.9 8.5 2.8 8.4 1.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF914 PF06027.7 KXX76738.1 - 5.9e-95 317.9 18.4 8.3e-95 317.4 12.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KXX76738.1 - 2.4e-08 34.0 8.9 2.4e-08 34.0 6.2 3.3 2 2 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 KXX76738.1 - 0.0015 17.5 10.0 0.0028 16.6 7.0 1.5 1 1 0 1 1 1 1 UAA transporter family FUSC-like PF12805.2 KXX76738.1 - 0.26 10.1 7.4 0.032 13.1 0.9 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PAP_assoc PF03828.14 KXX76739.1 - 6.5e-17 61.2 0.1 1.4e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KXX76739.1 - 1.7e-06 28.2 0.0 3.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain CCDC-167 PF15188.1 KXX76739.1 - 0.25 11.3 1.6 0.55 10.2 1.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Abhydrolase_1 PF00561.15 KXX76743.1 - 7.3e-19 68.2 0.0 1e-16 61.2 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX76743.1 - 2.3e-12 47.3 6.7 2.4e-11 43.9 4.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KXX76743.1 - 0.00092 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DnaJ PF00226.26 KXX76745.1 - 5.4e-19 67.6 2.2 5.4e-19 67.6 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain TraH PF06122.6 KXX76745.1 - 0.23 10.2 3.5 0.36 9.5 2.5 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein RRM_1 PF00076.17 KXX76746.1 - 2.8e-10 39.6 0.0 4.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX76746.1 - 1.7e-09 37.3 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX76746.1 - 3.4e-07 30.1 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX76746.1 - 0.00047 19.8 0.1 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif NUDIX PF00293.23 KXX76747.1 - 9.2e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TauD PF02668.11 KXX76748.1 - 1.3e-25 90.5 0.2 1.6e-25 90.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NUDIX PF00293.23 KXX76749.1 - 2.5e-17 62.7 0.0 4.1e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peptidase_M43 PF05572.8 KXX76750.1 - 2.1e-16 59.8 0.1 4.3e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KXX76750.1 - 0.013 15.5 0.8 0.025 14.6 0.6 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX76750.1 - 0.014 15.3 1.2 0.026 14.4 0.8 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M7 PF02031.11 KXX76750.1 - 0.03 14.0 0.1 0.085 12.5 0.1 1.8 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 KXX76750.1 - 0.035 13.6 0.7 0.074 12.5 0.3 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KXX76750.1 - 0.057 13.1 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.1 KXX76750.1 - 0.068 13.7 0.2 0.13 12.7 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ABM PF03992.11 KXX76750.1 - 0.073 13.1 0.2 0.58 10.2 0.0 2.2 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Tyrosinase PF00264.15 KXX76751.1 - 6.8e-49 167.0 0.1 8.6e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Complex1_LYR PF05347.10 KXX76752.1 - 2.5e-06 27.2 0.4 3.6e-06 26.6 0.2 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX76752.1 - 1.7e-05 24.9 0.3 2.2e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 KXX76752.1 - 0.0024 17.6 0.2 0.0027 17.4 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Complex1_LYR_2 PF13233.1 KXX76752.1 - 0.005 17.3 0.1 0.007 16.8 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Synaphin PF05835.7 KXX76752.1 - 0.14 12.3 0.7 0.77 9.9 0.0 1.9 1 1 1 2 2 2 0 Synaphin protein Sterol_MT_C PF08498.5 KXX76753.1 - 3.5e-28 97.3 0.5 5.4e-28 96.7 0.4 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KXX76753.1 - 7.6e-22 77.6 0.0 1.7e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76753.1 - 2.3e-17 63.0 0.0 3.5e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX76753.1 - 1.6e-13 50.8 0.0 3.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX76753.1 - 3.1e-13 49.7 0.0 5.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX76753.1 - 1.3e-12 47.3 0.1 2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KXX76753.1 - 3.7e-12 46.7 0.0 1.9e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76753.1 - 7e-12 45.6 0.2 2.3e-11 44.0 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX76753.1 - 5e-11 42.1 0.0 9.2e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX76753.1 - 4.4e-09 36.4 0.0 1.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX76753.1 - 5.1e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KXX76753.1 - 0.00021 20.8 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KXX76753.1 - 0.00023 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 KXX76753.1 - 0.00041 19.5 0.0 0.00095 18.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 KXX76753.1 - 0.00055 18.3 0.0 0.00097 17.5 0.0 1.3 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.5 KXX76753.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 KXX76753.1 - 0.0015 17.6 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 KXX76753.1 - 0.0018 17.4 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 KXX76753.1 - 0.0086 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 KXX76753.1 - 0.043 14.6 0.0 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KXX76753.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Transket_pyr PF02779.19 KXX76754.1 - 1e-46 158.6 0.0 1.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KXX76754.1 - 6.5e-36 122.9 0.1 2.5e-35 121.1 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain AIG2_2 PF13772.1 KXX76755.1 - 2.4e-05 24.3 0.0 6.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KXX76755.1 - 0.006 17.0 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family PMM PF03332.8 KXX76756.1 - 3.5e-11 43.0 0.0 5.6e-11 42.4 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KXX76756.1 - 2.5e-07 30.5 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KXX76756.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase ISN1 PF06437.6 KXX76756.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase iPGM_N PF06415.8 KXX76757.1 - 7.6e-74 247.8 0.0 1e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KXX76757.1 - 9.1e-72 241.4 0.0 1e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KXX76757.1 - 8.9e-06 25.2 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX76757.1 - 1e-05 24.8 0.0 0.00019 20.7 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 KXX76757.1 - 0.0026 17.0 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phage_int_SAM_1 PF02899.12 KXX76758.1 - 0.00043 20.3 0.9 0.0059 16.7 0.3 2.2 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain GCR1_C PF12550.3 KXX76759.1 - 9.5e-23 79.8 2.0 1.5e-22 79.2 1.4 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes F5_F8_type_C PF00754.20 KXX76759.1 - 0.00023 20.9 0.3 0.00045 20.0 0.2 1.4 1 0 0 1 1 1 1 F5/8 type C domain TMEM240 PF15207.1 KXX76759.1 - 3.8 7.0 5.9 0.86 9.1 1.6 1.7 2 0 0 2 2 2 0 TMEM240 family ADK PF00406.17 KXX76760.1 - 1.6e-26 92.9 0.0 2.1e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KXX76760.1 - 1.6e-09 37.8 0.0 4.8e-09 36.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX76760.1 - 1.6e-08 35.4 0.0 2.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX76760.1 - 1.9e-06 28.2 0.0 1.5e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KXX76760.1 - 0.00027 20.0 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 KXX76760.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX76760.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX76760.1 - 0.02 14.8 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KXX76760.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3987 PF13148.1 KXX76760.1 - 0.049 12.1 0.0 0.083 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_tran PF00005.22 KXX76760.1 - 0.078 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KXX76760.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KXX76760.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain CYTH PF01928.16 KXX76761.1 - 2e-11 43.8 0.0 3.6e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 CYTH domain NAD_binding_1 PF00175.16 KXX76762.1 - 6.3e-29 100.7 0.0 9.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KXX76762.1 - 4e-15 55.7 0.0 6.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KXX76762.1 - 4.3e-09 36.4 0.0 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Gpi1 PF05024.10 KXX76763.1 - 1.4e-66 223.7 8.0 2.6e-66 222.9 5.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 KXX76763.1 - 7.7e-26 89.7 2.2 1.7e-25 88.6 1.6 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.16 KXX76763.1 - 0.001 18.2 1.0 0.001 18.2 0.7 2.7 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) Tom37_C PF11801.3 KXX76763.1 - 0.029 14.2 0.7 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Tom37 C-terminal domain TBCC PF07986.7 KXX76764.1 - 3.2e-34 116.9 0.0 4.7e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF3060 PF11259.3 KXX76764.1 - 0.061 12.9 1.9 0.16 11.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Radical_SAM PF04055.16 KXX76765.1 - 2e-13 50.8 0.1 3.7e-13 49.9 0.1 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KXX76765.1 - 5.9e-07 29.6 0.0 9.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KXX76765.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DNA_pol_A_exo1 PF01612.15 KXX76766.1 - 3.6e-43 147.0 0.2 7.2e-43 146.0 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KXX76766.1 - 4.6e-26 90.9 0.1 1.3e-25 89.4 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KXX76766.1 - 3e-10 39.6 0.0 6.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Prefoldin PF02996.12 KXX76767.1 - 5.8e-36 122.7 0.0 8.9e-36 122.1 0.0 1.3 1 0 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 KXX76767.1 - 0.0005 19.7 0.4 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 Hr1 repeat Syntaxin-6_N PF09177.6 KXX76767.1 - 0.026 14.9 1.3 4.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Filament PF00038.16 KXX76767.1 - 0.029 13.8 0.9 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.15 KXX76767.1 - 0.059 13.1 5.6 0.18 11.5 0.0 2.8 3 0 0 3 3 3 0 Prefoldin subunit DUF4201 PF13870.1 KXX76767.1 - 0.22 10.9 3.5 0.31 10.4 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF2353 PF09789.4 KXX76767.1 - 0.24 10.6 4.2 1 8.5 2.9 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) SlyX PF04102.7 KXX76767.1 - 1 9.8 5.2 1.5 9.2 0.1 3.1 3 1 1 4 4 4 0 SlyX V-SNARE PF05008.10 KXX76767.1 - 1.1 9.4 4.4 0.97 9.6 0.8 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.8 KXX76767.1 - 1.2 9.9 4.4 15 6.3 1.4 2.2 2 0 0 2 2 2 0 Occludin homology domain Med9 PF07544.8 KXX76768.1 - 1.1e-16 60.2 0.0 4.6e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Asp PF00026.18 KXX76769.1 - 1.6e-110 369.3 0.7 1.9e-110 369.0 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX76769.1 - 1.7e-13 50.8 0.0 1e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KXX76769.1 - 4e-07 30.4 0.1 0.039 14.4 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KXX76769.1 - 0.00022 20.7 0.0 0.0025 17.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 KXX76769.1 - 0.046 13.8 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain TauD PF02668.11 KXX76770.1 - 2.4e-34 119.2 1.0 1.7e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family UvrC_HhH_N PF08459.6 KXX76770.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal WD40 PF00400.27 KXX76772.1 - 0.25 11.2 10.1 0.48 10.3 0.8 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat TLP-20 PF06088.6 KXX76772.1 - 3.2 7.4 6.6 6.9 6.3 4.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HlyIII PF03006.15 KXX76775.1 - 3.8e-46 157.2 19.1 4.6e-42 143.9 8.9 2.1 1 1 1 2 2 2 2 Haemolysin-III related Pkinase PF00069.20 KXX76776.1 - 2e-60 204.1 0.0 2.6e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76776.1 - 1.1e-32 113.1 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX76776.1 - 2.1e-05 23.6 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX76776.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KXX76776.1 - 0.05 12.4 0.2 0.095 11.4 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KXX76776.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KXX76776.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4237 PF14021.1 KXX76777.1 - 1.4e-32 111.8 0.1 2.7e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) DEAD PF00270.24 KXX76778.1 - 6.6e-40 136.3 0.2 1.1e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX76778.1 - 1.1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KXX76778.1 - 3.9e-14 51.9 0.0 8e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KXX76778.1 - 0.0031 17.3 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CBM_1 PF00734.13 KXX76779.1 - 5.4e-10 38.7 16.6 5.4e-10 38.7 11.5 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 KXX76779.1 - 0.0096 15.8 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX76779.1 - 0.013 14.9 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KXX76779.1 - 0.014 14.6 0.4 0.026 13.7 0.3 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KXX76779.1 - 0.017 14.8 0.2 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX76779.1 - 0.055 12.6 0.7 0.095 11.9 0.5 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_10 PF00331.15 KXX76780.1 - 2.8e-105 351.8 0.1 3.2e-105 351.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KXX76780.1 - 1.9e-14 53.0 11.0 5.2e-14 51.5 7.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain LysM PF01476.15 KXX76783.1 - 3e-11 43.0 0.0 0.0061 16.4 0.0 3.3 3 0 0 3 3 3 3 LysM domain Glycoprotein PF03409.10 KXX76783.1 - 0.0015 17.3 6.7 0.21 10.3 0.3 2.1 2 0 0 2 2 2 2 Transmembrane glycoprotein RSS_P20 PF11757.3 KXX76784.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Glyco_hydro_62 PF03664.8 KXX76785.1 - 9.6e-143 474.1 6.0 1.1e-142 473.9 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Peptidase_M43 PF05572.8 KXX76786.1 - 6.6e-12 45.2 2.6 7.8e-12 45.0 1.2 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KXX76786.1 - 4.8e-05 23.4 0.7 7.2e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KXX76786.1 - 0.0033 17.9 0.7 0.0077 16.7 0.5 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX76786.1 - 0.0041 17.0 2.1 0.016 15.1 1.4 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KXX76786.1 - 0.0072 16.0 0.1 0.011 15.4 0.1 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 KXX76786.1 - 0.012 15.1 0.7 0.017 14.6 0.4 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.20 KXX76788.1 - 9.3e-08 32.1 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76788.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76788.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain OTT_1508_deam PF14441.1 KXX76789.1 - 6.3e-08 32.5 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DALR_2 PF09190.6 KXX76789.1 - 0.022 14.9 0.1 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 DALR domain DUF3844 PF12955.2 KXX76790.1 - 6.8e-36 122.4 2.6 6.8e-36 122.4 1.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_CA PF07645.10 KXX76790.1 - 0.11 12.5 6.9 0.25 11.3 4.8 1.6 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_2 PF07974.8 KXX76790.1 - 0.14 12.3 8.0 0.29 11.3 5.6 1.6 1 0 0 1 1 1 0 EGF-like domain WW PF00397.21 KXX76792.1 - 1.3e-06 28.1 6.4 3.3e-06 26.8 4.5 1.8 1 0 0 1 1 1 1 WW domain BAR PF03114.13 KXX76792.1 - 0.64 9.4 6.2 0.96 8.9 4.3 1.1 1 0 0 1 1 1 0 BAR domain Gly-zipper_OmpA PF13436.1 KXX76792.1 - 2.1 7.9 7.3 0.24 11.0 1.6 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4404 PF14357.1 KXX76792.1 - 7.2 7.0 6.1 12 6.4 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Rhodanese PF00581.15 KXX76793.1 - 4.9e-05 23.6 0.0 7.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain LSM PF01423.17 KXX76794.1 - 1.4e-19 69.4 0.4 1.6e-19 69.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 KXX76795.1 - 3.7e-77 259.0 17.5 7.6e-77 257.9 9.9 2.2 2 1 0 2 2 2 1 Nineteen complex-related protein 2 DUF948 PF06103.6 KXX76795.1 - 0.0011 18.7 0.6 0.0023 17.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF896 PF05979.7 KXX76795.1 - 0.66 9.6 0.0 0.66 9.6 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF896) Zip PF02535.17 KXX76796.1 - 1e-48 166.0 0.3 1.5e-48 165.4 0.2 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3357 PF11837.3 KXX76796.1 - 0.041 13.7 1.5 5.6 6.8 0.0 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) AXE1 PF05448.7 KXX76797.1 - 0.0088 14.5 0.0 0.02 13.3 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) RGS PF00615.14 KXX76798.1 - 0.00011 22.2 0.0 0.0014 18.6 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2721 PF11026.3 KXX76798.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) 7TM-7TMR_HD PF07698.6 KXX76798.1 - 0.36 10.2 8.5 0.53 9.7 1.4 2.4 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Peptidase_C14 PF00656.17 KXX76799.1 - 2e-69 234.0 0.0 2.4e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DUF904 PF06005.7 KXX76800.1 - 0.087 13.1 0.8 0.26 11.6 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Malic_M PF03949.10 KXX76801.1 - 8.6e-81 271.2 0.1 1.1e-80 270.8 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KXX76801.1 - 4e-66 222.0 0.0 6.1e-66 221.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DOMON PF03351.12 KXX76802.1 - 0.00023 21.0 0.1 0.00083 19.2 0.0 1.8 1 1 1 2 2 2 2 DOMON domain FIVAR PF07554.8 KXX76803.1 - 2.5 8.4 6.7 0.37 11.0 1.2 2.0 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain BNR PF02012.15 KXX76804.1 - 0.61 10.1 4.5 0.39 10.7 0.3 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Zn_clus PF00172.13 KXX76805.1 - 6.8e-05 22.6 3.5 0.00013 21.7 2.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.8 KXX76805.1 - 0.7 9.9 5.2 2 8.4 3.6 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Beta-lactamase PF00144.19 KXX76806.1 - 9.2e-26 90.6 0.4 2.5e-25 89.2 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase Glyco_tranf_2_3 PF13641.1 KXX76807.1 - 6.7e-20 71.8 0.1 9.6e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KXX76807.1 - 2.9e-07 29.9 0.3 2.1e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX76807.1 - 4.2e-07 29.7 0.0 6.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Enkurin PF13864.1 KXX76807.1 - 0.007 16.5 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Calmodulin-binding OPT PF03169.10 KXX76808.1 - 1.3e-86 291.4 51.0 1.6e-86 291.1 35.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.19 KXX76809.1 - 2.3e-112 375.8 23.1 2.6e-112 375.6 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX76809.1 - 1.5e-23 83.1 49.0 3.4e-22 78.6 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KXX76810.1 - 8.4e-18 64.8 9.1 3e-12 46.8 1.6 3.4 2 1 1 3 3 3 3 Heterokaryon incompatibility protein (HET) Ribosomal_L14 PF00238.14 KXX76811.1 - 2.3e-32 111.2 0.0 2.6e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2413 PF10310.4 KXX76812.1 - 6.5e-148 493.2 0.0 7.5e-148 493.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KXX76812.1 - 0.0099 15.8 1.1 0.021 14.8 0.1 2.0 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain F-box PF00646.28 KXX76813.1 - 1e-09 37.7 1.1 1.2e-05 24.7 0.0 3.7 4 0 0 4 4 4 2 F-box domain F-box-like PF12937.2 KXX76813.1 - 5.6e-06 25.9 0.5 0.00031 20.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KXX76813.1 - 0.083 12.5 0.0 15 5.3 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DNA_pol_phi PF04931.8 KXX76813.1 - 0.19 9.4 21.6 0.27 8.9 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.7 KXX76813.1 - 1.3 6.8 8.7 2 6.2 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 KXX76815.1 - 6.5e-10 38.3 0.0 1.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_2 PF12681.2 KXX76816.1 - 1.1e-08 35.5 0.1 1.7e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KXX76816.1 - 0.00017 21.5 0.0 0.00024 21.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PFL PF02901.10 KXX76817.1 - 0.16 10.3 0.0 0.22 9.9 0.0 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase Fungal_trans_2 PF11951.3 KXX76818.1 - 5.1e-06 25.3 1.5 6.8e-06 24.9 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 KXX76819.1 - 2.1e-59 201.6 0.0 3.4e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX76819.1 - 2.6e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX76819.1 - 0.0038 16.4 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family E1-E2_ATPase PF00122.15 KXX76820.1 - 6.3e-65 218.4 1.7 6.3e-65 218.4 1.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX76820.1 - 4.3e-32 111.1 6.5 4.3e-32 111.1 4.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX76820.1 - 1.2e-29 104.2 0.0 1.1e-28 101.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX76820.1 - 3.3e-18 65.4 0.0 7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KXX76820.1 - 1.5e-16 59.6 0.1 7e-16 57.4 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KXX76820.1 - 2.4e-14 53.9 0.0 6.8e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX76820.1 - 0.0012 18.4 0.2 0.0062 16.1 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 KXX76820.1 - 0.026 14.0 0.3 0.069 12.7 0.2 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B Peroxidase_2 PF01328.12 KXX76821.1 - 9.4e-38 129.6 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 ATX_III PF08098.6 KXX76823.1 - 0.033 13.9 0.5 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family RNA_helicase PF00910.17 KXX76823.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase 2-Hacid_dh_C PF02826.14 KXX76824.1 - 1.5e-25 89.3 0.1 5.6e-12 45.1 0.0 3.5 1 1 1 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KXX76824.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 KXX76824.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_11 PF00457.12 KXX76825.1 - 2.8e-61 206.0 11.5 3.2e-61 205.8 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 NAD_binding_8 PF13450.1 KXX76826.1 - 0.032 14.2 0.3 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KXX76826.1 - 0.096 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 KXX76827.1 - 1.2e-13 50.6 0.0 2.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.9 KXX76828.1 - 5.1e-14 51.9 0.7 8e-14 51.3 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KXX76828.1 - 0.0013 18.3 0.6 0.0013 18.3 0.4 2.4 3 0 0 3 3 3 1 Nudix N-terminal zf-DNL PF05180.7 KXX76828.1 - 4.6 7.0 7.7 0.95 9.2 0.9 2.2 2 0 0 2 2 2 0 DNL zinc finger DUF1857 PF08982.6 KXX76830.1 - 4.4e-46 156.1 0.1 4.8e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF1785 PF08699.5 KXX76831.1 - 4.8e-15 54.6 0.1 8.3e-15 53.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) 2OG-FeII_Oxy_4 PF13661.1 KXX76831.1 - 0.076 12.6 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Piwi PF02171.12 KXX76832.1 - 4.9e-78 262.1 0.0 8.4e-78 261.3 0.0 1.4 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 KXX76832.1 - 4.6e-12 45.4 0.0 8.4e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain NmrA PF05368.8 KXX76833.1 - 1.9e-14 53.5 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX76833.1 - 9.1e-12 45.3 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX76833.1 - 1.4e-07 31.2 0.0 1.9e-06 27.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KXX76833.1 - 0.0057 17.0 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KXX76833.1 - 0.0067 16.1 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX76833.1 - 0.013 15.4 0.2 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KXX76833.1 - 0.014 14.2 0.1 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KXX76833.1 - 0.015 14.2 0.1 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KXX76833.1 - 0.021 13.8 0.3 0.032 13.2 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KXX76833.1 - 0.03 13.0 0.1 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KXX76833.1 - 0.042 13.7 0.5 0.083 12.8 0.4 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GARS_N PF02844.10 KXX76833.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Flavokinase PF01687.12 KXX76834.1 - 2.3e-36 124.3 0.0 3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAP1 PF08601.5 KXX76835.1 - 3e-53 181.7 6.7 3e-53 181.7 4.6 2.4 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KXX76835.1 - 6e-09 35.7 12.2 1.3e-08 34.6 8.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX76835.1 - 0.0017 18.1 15.8 0.006 16.3 10.9 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 KXX76835.1 - 0.012 16.1 1.8 0.012 16.1 1.3 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) ACCA PF03255.9 KXX76835.1 - 0.022 14.2 0.3 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit bZIP_Maf PF03131.12 KXX76835.1 - 0.14 12.4 9.7 0.32 11.3 6.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor EMP24_GP25L PF01105.19 KXX76835.1 - 0.19 11.4 1.5 0.36 10.5 1.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glutaredoxin2_C PF04399.8 KXX76835.1 - 0.46 10.0 2.7 0.88 9.1 1.9 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain V_ATPase_I PF01496.14 KXX76835.1 - 1.2 6.8 2.7 1.7 6.4 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KXX76835.1 - 1.6 8.2 5.6 2.8 7.4 3.9 1.3 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KXX76835.1 - 9.8 4.3 16.7 5.2 5.2 0.7 2.1 2 0 0 2 2 2 0 Transmembrane protein Pkinase PF00069.20 KXX76836.1 - 1.6e-59 201.2 0.0 2.1e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76836.1 - 1.3e-30 106.3 0.0 1.7e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX76836.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX76836.1 - 0.013 15.1 0.3 0.013 15.1 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KXX76836.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.1 KXX76837.1 - 5.9e-18 65.1 0.0 8.8e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76837.1 - 2e-14 54.0 0.0 2.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76837.1 - 9.4e-14 51.6 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX76837.1 - 1.4e-13 51.1 0.0 1.4e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX76837.1 - 1.5e-11 44.1 0.0 2.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX76837.1 - 2e-07 31.0 0.1 1.3e-06 28.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX76837.1 - 0.00015 22.1 0.0 0.00023 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KXX76837.1 - 0.00024 20.3 0.0 0.00092 18.4 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KXX76837.1 - 0.00087 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KXX76837.1 - 0.0097 15.0 0.0 0.65 9.0 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase HMG_CoA_synt_C PF08540.5 KXX76839.1 - 2.9e-98 328.8 0.0 4.5e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KXX76839.1 - 2.1e-94 313.9 0.4 3.1e-94 313.3 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.6 KXX76840.1 - 3.5e-55 186.5 2.0 3.5e-55 186.5 1.4 2.8 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KXX76840.1 - 6.9e-17 61.8 0.0 2.2e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX76840.1 - 0.00071 19.6 0.8 0.0063 16.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KXX76840.1 - 0.0016 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX76840.1 - 0.0032 16.5 0.0 0.0096 14.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX76840.1 - 0.004 16.8 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX76840.1 - 0.039 14.7 5.6 0.068 13.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KXX76840.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KXX76840.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain MIP-T3 PF10243.4 KXX76840.1 - 0.32 9.3 58.2 0.53 8.6 40.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 KXX76840.1 - 1.1 7.6 32.6 2.2 6.6 22.6 1.4 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 KXX76840.1 - 5.4 6.1 42.2 10 5.2 29.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Abhydrolase_3 PF07859.8 KXX76843.1 - 7.4e-38 130.2 0.1 6e-29 101.1 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX76843.1 - 3.8e-14 52.1 0.0 4.5e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KXX76843.1 - 0.00076 18.3 0.3 0.19 10.3 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 KXX76843.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family MRP-L27 PF09809.4 KXX76844.1 - 5.1e-18 64.7 0.4 6.4e-18 64.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 KXX76845.1 - 2.2e-185 617.9 49.9 2.2e-185 617.9 34.6 2.4 1 1 1 2 2 2 1 Utp14 protein WD40 PF00400.27 KXX76846.1 - 5.6e-71 232.1 11.4 1.3e-14 53.3 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 KXX76846.1 - 4.3e-19 68.7 0.0 1e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Gmad1 PF10647.4 KXX76846.1 - 5.7e-07 29.1 6.2 0.00015 21.2 1.4 3.9 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 KXX76846.1 - 2.1e-05 22.8 4.0 0.57 8.2 0.0 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 KXX76846.1 - 5.3e-05 22.7 6.1 7.3 6.3 0.1 4.6 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.6 KXX76846.1 - 8.1e-05 21.4 0.1 0.12 11.0 0.0 3.1 1 1 1 3 3 3 3 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.1 KXX76846.1 - 0.00032 20.2 2.0 0.0041 16.6 1.9 2.3 2 1 0 2 2 2 1 PQQ-like domain DUF1797 PF08796.5 KXX76846.1 - 0.0063 16.3 0.0 43 4.0 0.0 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1797) PIF1 PF05970.9 KXX76846.1 - 0.084 11.8 0.2 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AFG1_ATPase PF03969.11 KXX76846.1 - 0.15 10.8 0.0 0.31 9.7 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DHBP_synthase PF00926.14 KXX76847.1 - 1.2e-75 253.0 0.0 6e-75 250.7 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase BSD PF03909.12 KXX76848.1 - 5.5e-16 58.0 0.0 1.3e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 BSD domain BSP_II PF05432.6 KXX76848.1 - 0.0028 17.0 7.9 0.0028 17.0 5.5 2.6 2 1 1 3 3 3 1 Bone sialoprotein II (BSP-II) Suf PF05843.9 KXX76848.1 - 0.014 15.1 0.5 0.014 15.1 0.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 KXX76848.1 - 0.051 13.5 0.5 0.33 10.9 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_r2 PF04542.9 KXX76848.1 - 0.1 12.2 0.1 0.34 10.5 0.1 1.9 1 0 0 1 1 1 0 Sigma-70 region 2 ATG16 PF08614.6 KXX76848.1 - 0.42 10.3 8.3 0.044 13.6 1.4 2.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) RXT2_N PF08595.6 KXX76848.1 - 1.3 8.8 6.2 0.28 10.9 1.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 KXX76848.1 - 2.9 7.3 16.7 9.7 5.6 11.5 1.9 1 0 0 1 1 1 0 Nucleoplasmin S-antigen PF05756.6 KXX76848.1 - 3.4 7.7 6.0 0.73 9.8 1.0 2.3 2 0 0 2 2 2 0 S-antigen protein IFT57 PF10498.4 KXX76848.1 - 4.3 5.9 6.8 9.6 4.8 2.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 WGG PF10273.4 KXX76849.1 - 3.9e-36 123.0 0.4 7.1e-36 122.1 0.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KXX76849.1 - 0.0057 16.6 0.3 0.0057 16.6 0.2 2.4 2 1 1 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) SURF2 PF05477.6 KXX76849.1 - 3.6 6.6 8.7 4.2 6.4 1.5 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) NAD_binding_10 PF13460.1 KXX76850.1 - 8.3e-12 45.4 0.5 1.1e-11 45.0 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX76850.1 - 3.4e-09 36.4 0.0 1.1e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 KXX76850.1 - 1.6e-05 23.6 0.0 2.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.8 KXX76850.1 - 3.6e-05 23.1 0.0 7.3e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KXX76850.1 - 0.00037 19.5 0.0 0.66 8.8 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.14 KXX76850.1 - 0.0073 15.0 0.0 0.015 14.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KXX76850.1 - 0.0075 16.2 4.6 0.16 11.8 0.3 2.9 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KXX76850.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PAS PF00989.19 KXX76851.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 KXX76851.1 - 0.0015 18.3 8.6 0.0039 17.0 6.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transformer PF06495.6 KXX76851.1 - 2.5 7.9 10.0 11 5.8 6.9 2.0 1 1 0 1 1 1 0 Fruit fly transformer protein MFS_1 PF07690.11 KXX76852.1 - 8.1e-35 120.1 25.1 8.1e-35 120.1 17.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX76852.1 - 5.8e-06 24.7 3.1 8.9e-06 24.1 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SK_channel PF03530.9 KXX76852.1 - 0.079 12.8 0.3 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Transket_pyr PF02779.19 KXX76853.1 - 2e-43 147.9 0.0 4.2e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KXX76853.1 - 5.7e-33 113.4 0.2 1.3e-32 112.3 0.1 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Cellulase PF00150.13 KXX76854.1 - 1.3e-10 40.9 0.1 2.4e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Synaptobrevin PF00957.16 KXX76854.1 - 0.87 9.2 1.9 1.5 8.4 1.3 1.3 1 0 0 1 1 1 0 Synaptobrevin MULE PF10551.4 KXX76855.1 - 1.5e-15 57.1 0.0 4e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 KXX76855.1 - 1.1e-05 24.2 0.9 1.6e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Transposase, Mutator family DUF2121 PF09894.4 KXX76855.1 - 0.021 14.0 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) zf-RING_2 PF13639.1 KXX76856.1 - 9.3e-11 41.3 3.3 1.4e-10 40.8 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KXX76856.1 - 8e-07 29.0 0.1 2.2e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KXX76856.1 - 3.5e-05 23.5 0.3 5.8e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KXX76856.1 - 9.8e-05 21.9 0.4 0.00016 21.2 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX76856.1 - 0.00027 20.8 2.6 0.00043 20.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX76856.1 - 0.0011 18.5 0.8 0.0018 17.8 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX76856.1 - 0.01 15.5 0.6 0.018 14.7 0.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 KXX76856.1 - 0.098 12.2 3.5 0.36 10.4 2.6 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 KXX76856.1 - 0.11 11.9 4.4 0.25 10.8 0.3 2.4 2 1 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 KXX76856.1 - 0.16 11.9 1.8 2.6 8.0 1.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Di19 PF05605.7 KXX76856.1 - 0.17 12.0 0.8 21 5.3 0.1 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sec39 PF08314.6 KXX76857.1 - 1.5e-231 770.2 0.0 1.8e-231 769.9 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ribosomal_60s PF00428.14 KXX76859.1 - 2.6e-28 98.2 9.7 3e-28 98.0 6.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein GHMP_kinases_N PF00288.21 KXX76859.1 - 0.028 14.4 3.3 0.058 13.4 2.3 1.5 1 1 0 1 1 1 0 GHMP kinases N terminal domain Prog_receptor PF02161.10 KXX76859.1 - 0.12 11.1 3.0 0.14 10.9 2.1 1.0 1 0 0 1 1 1 0 Progesterone receptor EF-hand_9 PF14658.1 KXX76859.1 - 0.15 12.0 0.1 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.20 KXX76860.1 - 2.1e-44 151.6 0.0 3.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76860.1 - 2.3e-20 72.7 0.0 3.4e-19 68.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KXX76860.1 - 0.032 13.5 0.2 0.07 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family PsaA_PsaB PF00223.14 KXX76860.1 - 0.059 11.4 0.0 0.085 10.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S8e PF01201.17 KXX76861.1 - 1.4e-18 67.3 17.2 5.5e-17 62.1 12.0 2.4 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 KXX76861.1 - 2.1 8.5 5.6 4 7.6 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Tim17 PF02466.14 KXX76862.1 - 8.8e-29 100.1 0.4 1.2e-28 99.6 0.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyr_redox_3 PF13738.1 KXX76863.1 - 5.5e-13 49.4 0.0 1.5e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX76863.1 - 0.00073 19.4 0.0 0.007 16.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX76863.1 - 0.2 10.5 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IBR PF01485.16 KXX76864.1 - 0.00063 19.5 0.5 0.00063 19.5 0.4 2.8 2 1 0 2 2 2 1 IBR domain zf-RING_5 PF14634.1 KXX76864.1 - 0.0024 17.5 10.7 0.0024 17.5 7.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX76864.1 - 3.5 7.7 16.6 0.067 13.2 3.8 2.8 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX76864.1 - 6.6 6.6 20.9 0.45 10.3 7.2 2.7 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4 PF00097.20 KXX76864.1 - 8.1 6.1 17.6 0.97 9.1 5.9 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DIOX_N PF14226.1 KXX76865.1 - 2.6e-19 69.8 0.0 4.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX76865.1 - 1.8e-11 44.1 0.0 5.3e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GCD14 PF08704.5 KXX76866.1 - 6.4e-64 215.8 0.0 1.9e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KXX76866.1 - 0.00044 20.2 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76866.1 - 0.018 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.21 KXX76867.1 - 2e-153 511.3 4.0 2.6e-153 511.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX76867.1 - 1.1e-24 85.9 0.4 4.7e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Peptidase_A4 PF01828.12 KXX76868.1 - 1.2e-21 76.7 0.4 5.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase A4 family DUF2580 PF10824.3 KXX76869.1 - 0.001 19.3 1.2 0.001 19.3 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2580) NDK PF00334.14 KXX76870.1 - 1.7e-54 183.2 0.0 1.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase zf-C2H2 PF00096.21 KXX76871.1 - 0.00027 21.1 21.3 0.00049 20.2 0.5 5.0 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX76871.1 - 0.00036 20.6 15.7 0.067 13.5 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger UPF0175 PF03683.8 KXX76871.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) ELO PF01151.13 KXX76872.1 - 4.1e-08 32.8 2.2 9e-08 31.7 1.5 1.6 1 1 0 1 1 1 1 GNS1/SUR4 family WSC PF01822.14 KXX76873.1 - 3.5e-75 247.9 65.2 1.1e-19 70.0 4.9 4.1 4 0 0 4 4 4 4 WSC domain MS_channel PF00924.13 KXX76875.1 - 5.7e-20 71.5 2.6 1.1e-19 70.6 1.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 KXX76875.1 - 0.014 15.5 0.1 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KXX76875.1 - 0.038 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 KXX76875.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KXX76875.1 - 0.08 12.2 0.4 0.2 11.0 0.3 1.8 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.3 KXX76875.1 - 3.3 7.7 6.6 0.36 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function SPT2 PF08243.6 KXX76876.1 - 1.1e-07 32.1 25.3 1.1e-07 32.1 17.6 2.4 2 1 0 2 2 2 1 SPT2 chromatin protein IBR PF01485.16 KXX76877.1 - 4.2e-05 23.3 9.6 0.00018 21.2 3.0 2.4 2 0 0 2 2 2 2 IBR domain zf-C3HC4_4 PF15227.1 KXX76877.1 - 0.024 14.5 0.5 0.024 14.5 0.3 2.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KXX76877.1 - 0.024 14.2 1.8 0.024 14.2 1.3 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX76877.1 - 1.2 8.9 16.3 0.032 13.9 3.5 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Pkinase PF00069.20 KXX76878.1 - 1.7e-59 201.0 0.0 2.6e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX76878.1 - 1e-19 70.6 0.0 5.7e-19 68.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KXX76878.1 - 0.07 12.4 0.1 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Mtc PF03820.12 KXX76879.1 - 1e-105 352.7 0.2 4.1e-104 347.5 0.1 2.0 1 1 0 1 1 1 1 Tricarboxylate carrier UPF0240 PF06784.6 KXX76879.1 - 0.08 12.6 0.2 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Lactamase_B_2 PF12706.2 KXX76880.1 - 1.2e-32 112.9 0.0 2e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KXX76880.1 - 8.5e-27 92.4 0.0 2.3e-26 91.0 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KXX76880.1 - 3.7e-09 36.5 0.1 1.3e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily EB1 PF03271.12 KXX76881.1 - 5.5e-18 64.7 1.1 1.1e-17 63.7 0.7 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KXX76881.1 - 0.0003 20.7 0.4 0.00094 19.1 0.1 1.8 1 1 1 2 2 2 1 Calponin homology (CH) domain PX PF00787.19 KXX76882.1 - 2.6e-14 52.9 0.0 4.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KXX76882.1 - 5.7e-09 35.5 4.8 1.2e-08 34.5 3.3 1.6 1 0 0 1 1 1 1 SNARE domain HET PF06985.6 KXX76884.1 - 8.6e-07 29.1 0.0 0.00019 21.5 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 KXX76885.1 - 8.2e-60 202.3 0.6 3.3e-24 85.0 0.2 4.4 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 KXX76885.1 - 6.7e-11 42.7 0.1 2e-10 41.2 0.1 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 KXX76885.1 - 0.0051 16.5 1.0 0.014 15.1 0.7 1.7 1 0 0 1 1 1 1 Gas vesicle protein G DUF2183 PF09949.4 KXX76887.1 - 4.9e-32 109.8 0.0 1.2e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.1 KXX76887.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DEAD PF00270.24 KXX76889.1 - 5.8e-45 152.8 0.9 5.5e-44 149.6 0.1 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX76889.1 - 1.5e-24 85.6 0.0 3.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KXX76889.1 - 4.6e-05 22.0 0.9 0.00057 18.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) DUF4549 PF15082.1 KXX76889.1 - 0.061 12.9 1.6 0.7 9.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) DUF4407 PF14362.1 KXX76889.1 - 0.49 9.2 17.1 0.012 14.6 6.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) 5_nucleotid PF05761.9 KXX76889.1 - 1.4 7.3 6.2 2.1 6.7 4.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family SKG6 PF08693.5 KXX76890.1 - 0.062 12.6 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_16 PF00722.16 KXX76891.1 - 1.7e-08 33.9 0.0 3e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Polysacc_lyase PF14099.1 KXX76891.1 - 0.0061 16.2 0.4 0.016 14.9 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide lyase Flavin_Reduct PF01613.13 KXX76892.1 - 9.2e-16 58.0 0.1 1.3e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 KXX76893.1 - 3.4e-51 174.1 0.0 7.4e-23 81.0 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KXX76893.1 - 0.16 11.4 10.0 0.045 13.3 0.2 3.0 2 1 0 2 2 2 0 Beta-lactamase superfamily domain p450 PF00067.17 KXX76897.1 - 2.7e-22 78.9 0.3 1.6e-21 76.3 0.1 2.2 2 1 0 2 2 2 1 Cytochrome P450 Glyco_hydro_61 PF03443.9 KXX76898.1 - 2.1e-53 181.4 0.0 2.5e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 gerPA PF10676.4 KXX76898.1 - 0.048 13.5 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF HET PF06985.6 KXX76900.1 - 4.9e-17 62.3 0.1 9.8e-14 51.6 0.0 3.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KXX76903.1 - 1.4e-17 64.1 0.2 2.2e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX76903.1 - 7.7e-15 55.3 0.0 8.9e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX76903.1 - 9.6e-09 35.1 0.1 1.4e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX76903.1 - 3.2e-06 26.7 0.0 5.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KXX76903.1 - 6.2e-06 25.5 0.0 0.00064 18.9 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KXX76903.1 - 0.00077 19.5 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding PNP_UDP_1 PF01048.15 KXX76904.1 - 0.012 14.5 0.0 0.064 12.2 0.0 1.9 2 0 0 2 2 2 0 Phosphorylase superfamily DUF4334 PF14232.1 KXX76904.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) HET PF06985.6 KXX76905.1 - 5.1e-16 59.0 9.7 3.2e-14 53.2 1.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank PF00023.25 KXX76906.1 - 2.1e-08 33.5 0.1 6.7e-07 28.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 KXX76906.1 - 3.7e-08 33.5 0.1 5.1e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX76906.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX76906.1 - 2.7e-06 27.7 0.0 5.5e-06 26.7 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX76906.1 - 1.1e-05 25.1 0.0 6.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat p450 PF00067.17 KXX76907.1 - 2.1e-29 102.3 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KXX76908.1 - 5.2e-25 87.5 0.6 7.9e-25 86.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Epimerase PF01370.16 KXX76910.1 - 2.7e-13 49.9 0.1 7.1e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX76910.1 - 0.00034 19.6 0.0 0.0032 16.4 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KXX76910.1 - 0.00046 20.2 0.1 0.001 19.1 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX76910.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KXX76910.1 - 0.035 14.4 0.0 0.12 12.7 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PTSIIB_sorb PF03830.10 KXX76912.1 - 0.16 11.8 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component MMR_HSR1 PF01926.18 KXX76913.1 - 1.2e-08 34.9 0.0 1.1e-07 31.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX76913.1 - 1.6e-05 24.1 0.0 4.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KXX76913.1 - 6.8e-05 22.0 0.0 0.16 11.0 0.0 2.7 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.1 KXX76913.1 - 0.0032 16.9 0.0 0.0098 15.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KXX76913.1 - 0.0047 15.8 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KXX76913.1 - 0.0063 16.0 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KXX76913.1 - 0.0064 15.9 0.1 0.098 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain Septin PF00735.13 KXX76913.1 - 0.013 14.4 0.0 0.045 12.7 0.0 1.9 1 1 0 1 1 1 0 Septin DUF4254 PF14063.1 KXX76913.1 - 0.015 14.8 1.4 0.031 13.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) AAA_13 PF13166.1 KXX76913.1 - 0.019 13.4 1.6 0.051 12.0 1.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX76913.1 - 0.024 14.7 0.0 0.6 10.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KXX76913.1 - 0.031 13.9 3.4 0.078 12.6 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_16 PF13191.1 KXX76913.1 - 0.035 14.0 0.0 0.34 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KXX76913.1 - 0.05 13.2 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KXX76913.1 - 0.088 13.1 0.0 0.47 10.7 0.0 2.2 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 KXX76913.1 - 0.096 12.4 4.4 1.4 8.7 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KXX76913.1 - 0.49 10.6 7.1 1.9 8.7 0.1 2.8 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KXX76914.1 - 3.1e-40 137.9 27.5 3.1e-40 137.9 19.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MRP-L20 PF12824.2 KXX76915.1 - 2.5e-56 190.1 2.1 3.3e-56 189.7 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Hyccin PF09790.4 KXX76915.1 - 0.066 12.0 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Hyccin Sororin PF09666.5 KXX76916.1 - 0.023 14.8 0.1 0.052 13.7 0.1 1.6 1 0 0 1 1 1 0 Sororin protein PTR2 PF00854.16 KXX76917.1 - 2.8e-41 141.5 3.6 3e-40 138.1 2.5 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KXX76917.1 - 3.2e-08 32.7 16.6 3.2e-08 32.7 11.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3405 PF11885.3 KXX76918.1 - 5.5e-192 638.4 0.0 6.3e-192 638.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Trehalase PF01204.13 KXX76919.1 - 3.7e-195 649.4 0.0 4.4e-195 649.1 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KXX76919.1 - 1.9e-15 55.8 0.2 3.2e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain GATase_2 PF00310.16 KXX76920.1 - 7.6e-20 70.9 0.0 6.5e-15 54.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KXX76920.1 - 3.6e-16 59.3 0.0 7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KXX76920.1 - 8.1e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KXX76920.1 - 1.1e-11 44.4 0.1 2.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KXX76920.1 - 7.7e-06 24.7 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 KXX76920.1 - 0.24 10.9 1.8 1.4 8.4 0.0 2.9 4 0 0 4 4 4 0 Zinc-binding dehydrogenase ICL PF00463.16 KXX76922.1 - 1.1e-289 961.0 0.6 1.2e-289 960.8 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KXX76922.1 - 3.3e-12 46.1 0.2 7.4e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glyco_trans_2_3 PF13632.1 KXX76923.1 - 3.2e-46 157.4 2.1 3.2e-46 157.4 1.4 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX76923.1 - 2.1e-06 27.7 0.1 1.1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KXX76923.1 - 0.00012 21.8 0.0 0.00044 19.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 TrbE PF11100.3 KXX76923.1 - 0.7 9.7 4.7 1.7 8.5 3.3 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TrbE FYVE PF01363.16 KXX76924.1 - 0.0013 18.5 4.1 0.0013 18.5 2.8 3.0 3 1 0 3 3 3 1 FYVE zinc finger Sporozoite_P67 PF05642.6 KXX76924.1 - 0.064 11.1 7.4 0.1 10.4 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KXX76924.1 - 0.16 11.7 10.0 0.36 10.5 7.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FYVE_2 PF02318.11 KXX76924.1 - 1.8 8.5 6.2 3.8 7.4 1.0 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.19 KXX76924.1 - 5 7.1 10.7 1.2 9.1 1.0 3.2 3 0 0 3 3 3 0 B-box zinc finger p450 PF00067.17 KXX76925.1 - 8e-49 166.3 0.0 2.1e-48 164.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.18 KXX76926.1 - 6.9e-56 189.2 0.2 9.7e-56 188.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KXX76926.1 - 2.5e-25 88.1 0.8 9.4e-25 86.3 0.6 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KXX76926.1 - 1.6e-13 50.3 0.0 8.6e-13 47.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX76926.1 - 0.0013 18.6 0.5 0.028 14.2 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Rsc14 PF08586.5 KXX76926.1 - 0.49 10.9 6.8 0.3 11.5 1.1 2.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Acyl-CoA_dh_1 PF00441.19 KXX76927.1 - 8.7e-15 55.1 0.0 5.8e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX76927.1 - 1.6e-06 27.5 0.3 2.2e-05 23.8 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KXX76927.1 - 0.00036 20.7 0.1 0.3 11.3 0.0 3.0 4 0 0 4 4 4 2 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.10 KXX76928.1 - 1.3e-189 631.6 44.7 1.5e-189 631.4 31.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DHFR_1 PF00186.14 KXX76929.1 - 9.2e-28 96.8 0.0 8.6e-27 93.6 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.7 KXX76930.1 - 1.7e-36 125.1 3.5 5.5e-36 123.5 2.2 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone RIX1 PF08167.7 KXX76931.1 - 6.8e-45 152.7 1.2 8.9e-45 152.3 0.1 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TraV PF09676.5 KXX76931.1 - 0.034 14.8 0.3 0.034 14.8 0.2 3.1 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) TPR_2 PF07719.12 KXX76932.1 - 2e-07 30.3 18.6 0.55 10.2 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX76932.1 - 2.2e-07 30.8 25.2 0.023 15.3 0.2 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX76932.1 - 3.3e-07 29.8 7.9 1.8 8.2 0.0 6.2 6 0 0 6 6 6 3 TPR repeat TPR_8 PF13181.1 KXX76932.1 - 0.0027 17.3 2.8 0.15 11.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX76932.1 - 0.0059 16.7 2.5 1.5 9.1 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX76932.1 - 0.0068 16.7 13.8 0.064 13.5 0.1 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX76932.1 - 0.0081 15.7 8.2 11 5.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX76932.1 - 0.045 14.4 33.2 1.6 9.5 0.0 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX76932.1 - 0.11 12.3 11.2 12 5.9 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KXX76932.1 - 1.1 9.1 9.5 6.2 6.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX76932.1 - 6.7 7.4 10.9 26 5.5 0.4 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cutinase PF01083.17 KXX76934.1 - 1.2e-41 142.4 0.3 1.4e-41 142.1 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KXX76934.1 - 0.013 14.9 0.2 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain HET PF06985.6 KXX76935.1 - 6.9e-16 58.6 0.5 1.6e-15 57.4 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Dus PF01207.12 KXX76936.1 - 1e-58 198.6 0.0 1.7e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KXX76936.1 - 0.048 12.5 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Glyco_hydro_16 PF00722.16 KXX76937.1 - 4.2e-11 42.4 3.0 6.4e-11 41.8 2.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3439 PF11921.3 KXX76938.1 - 3.8 7.2 11.1 0.23 11.2 3.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SnoaL_2 PF12680.2 KXX76939.1 - 0.0063 16.8 0.6 0.011 16.1 0.4 1.5 1 1 0 1 1 1 1 SnoaL-like domain Bactofilin PF04519.8 KXX76941.1 - 5e-07 29.6 0.4 3.3e-06 27.0 0.1 2.0 1 1 1 2 2 2 1 Polymer-forming cytoskeletal DUF342 PF03961.8 KXX76941.1 - 0.00029 19.3 2.2 0.00074 18.0 1.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF342) DUF490 PF04357.8 KXX76941.1 - 0.024 13.7 0.0 0.72 8.8 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF490) Chorion_1 PF01723.11 KXX76941.1 - 0.056 13.3 1.0 8.6 6.2 0.0 2.6 1 1 1 2 2 2 0 Chorion protein SpoVG PF04026.7 KXX76941.1 - 0.074 13.0 0.1 0.5 10.4 0.0 2.2 1 1 1 2 2 2 0 SpoVG zf-C2H2 PF00096.21 KXX76942.1 - 0.014 15.6 3.4 0.037 14.3 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX76942.1 - 0.027 14.8 2.8 0.075 13.3 1.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 KXX76942.1 - 0.037 13.7 2.2 0.086 12.6 1.5 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.1 KXX76942.1 - 0.17 12.2 2.6 12 6.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DPM2 PF07297.7 KXX76944.1 - 8.1e-37 125.3 2.5 9.5e-37 125.1 1.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KXX76944.1 - 2.1e-05 24.1 0.9 2.4e-05 23.9 0.6 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KXX76944.1 - 0.00067 19.5 0.9 0.00067 19.5 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KXX76944.1 - 0.016 15.0 0.1 0.016 15.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) COX14 PF14880.1 KXX76944.1 - 0.049 13.2 2.2 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF1049 PF06305.6 KXX76944.1 - 0.051 13.0 0.3 0.051 13.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cytochrom_C_asm PF01578.15 KXX76944.1 - 0.051 13.1 0.2 0.055 13.0 0.1 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF1469 PF07332.6 KXX76944.1 - 0.1 12.3 1.4 0.15 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DiS_P_DiS PF06750.8 KXX76944.1 - 0.12 12.1 0.4 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PspC PF04024.7 KXX76944.1 - 1.4 8.4 5.4 11 5.6 0.1 2.2 2 0 0 2 2 2 0 PspC domain TPPK_C PF12555.3 KXX76944.1 - 2.5 7.8 8.5 3 7.6 0.8 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal HAMP PF00672.20 KXX76944.1 - 5.6 7.2 6.4 8 6.7 0.2 2.1 2 0 0 2 2 2 0 HAMP domain ketoacyl-synt PF00109.21 KXX76945.1 - 1.6e-58 198.2 8.4 4.8e-57 193.3 1.3 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX76945.1 - 3.8e-35 120.3 2.0 1.8e-34 118.1 1.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KXX76945.1 - 8.6e-06 24.9 0.1 9.1e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX76945.1 - 0.0011 18.3 4.1 0.0085 15.5 0.2 3.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain Dioxygenase_C PF00775.16 KXX76946.1 - 1e-51 174.8 0.0 1.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KXX76946.1 - 3.3e-12 46.2 0.0 5.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KXX76946.1 - 1.3e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 KXX76947.1 - 2.2e-26 92.2 0.0 4e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.24 KXX76948.1 - 1.3e-09 37.6 6.7 2e-09 36.9 4.6 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KXX76948.1 - 0.00023 21.4 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding MIF4G PF02854.14 KXX76949.1 - 5.8e-25 87.9 2.0 8.6e-25 87.3 0.8 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KXX76949.1 - 2.4e-23 81.9 0.1 1.2e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.1 KXX76949.1 - 1.3 8.7 10.0 0.23 11.1 4.2 1.8 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.7 KXX76949.1 - 1.8 7.7 8.8 3 7.0 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_61 PF03443.9 KXX76950.1 - 3.1e-81 272.3 0.0 4.2e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 YTH PF04146.10 KXX76951.1 - 1.4e-35 121.8 0.2 4.8e-34 116.9 0.1 2.2 1 1 0 1 1 1 1 YT521-B-like domain zf-C2H2 PF00096.21 KXX76951.1 - 0.016 15.5 0.2 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KXX76951.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KXX76951.1 - 0.065 13.6 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Velvet PF11754.3 KXX76952.1 - 7.7e-55 185.6 0.0 1.4e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 Velvet factor DUF2456 PF10445.4 KXX76954.1 - 1.9e-10 40.5 1.7 1.9e-10 40.5 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) Mannosyl_trans2 PF04188.8 KXX76955.1 - 1e-65 222.4 0.8 1.9e-65 221.5 0.5 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Glyco_hydro_2_C PF02836.12 KXX76956.1 - 7.2e-102 340.2 0.1 3.6e-101 337.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KXX76956.1 - 1.7e-46 158.4 0.0 3.1e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KXX76956.1 - 3.7e-45 153.4 0.2 6.4e-45 152.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KXX76956.1 - 6.3e-12 45.9 0.0 1.4e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Hira PF07569.6 KXX76958.1 - 2e-87 291.9 0.0 4e-87 291.0 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KXX76958.1 - 2.4e-39 131.8 22.8 7e-07 28.9 0.1 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 KXX76958.1 - 5e-11 41.8 0.6 1.1e-10 40.7 0.4 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KXX76958.1 - 0.0011 18.5 0.2 37 4.1 0.0 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KXX76958.1 - 0.43 8.3 0.2 2 6.1 0.0 2.1 2 1 1 3 3 3 0 IKI3 family CBM_1 PF00734.13 KXX76959.1 - 1e-11 44.2 9.3 2.4e-11 43.0 6.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 KXX76959.1 - 8.1e-05 21.8 43.0 0.29 11.1 0.3 9.5 12 0 0 12 12 12 6 BNR/Asp-box repeat Acetyltransf_7 PF13508.1 KXX76960.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX76960.1 - 0.00028 20.8 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DBINO PF13892.1 KXX76961.1 - 3.1 7.8 12.7 3.8 7.5 8.8 1.2 1 0 0 1 1 1 0 DNA-binding domain Mitofilin PF09731.4 KXX76961.1 - 4.4 5.8 16.7 4.5 5.8 11.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DEAD PF00270.24 KXX76962.1 - 6.2e-42 142.9 0.1 1.5e-41 141.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX76962.1 - 6.4e-25 86.8 0.0 1.3e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KXX76962.1 - 1.3e-06 27.4 0.0 1.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KXX76962.1 - 0.00034 20.4 0.1 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KXX76962.1 - 0.0024 16.3 0.0 0.28 9.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) FtsJ PF01728.14 KXX76963.1 - 8.5e-61 205.0 0.0 1.1e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zip PF02535.17 KXX76964.1 - 1.1e-27 96.9 31.8 1.4e-11 43.9 4.4 3.6 2 1 1 3 3 3 3 ZIP Zinc transporter Cation_efflux PF01545.16 KXX76964.1 - 1 8.3 10.8 0.025 13.6 2.8 1.7 2 0 0 2 2 2 0 Cation efflux family N2227 PF07942.7 KXX76965.1 - 1.1e-62 211.4 0.0 2.6e-62 210.2 0.0 1.5 1 1 1 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.7 KXX76965.1 - 1.1e-06 28.9 0.1 5.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX76965.1 - 0.00074 19.2 0.0 0.0023 17.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX76965.1 - 0.0014 19.0 0.0 0.008 16.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76965.1 - 0.0032 18.0 0.0 0.015 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Nif11 PF07862.6 KXX76965.1 - 0.025 14.5 0.3 6.6 6.7 0.0 3.1 3 0 0 3 3 3 0 Nitrogen fixation protein of unknown function Imm15 PF15590.1 KXX76965.1 - 0.15 11.1 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 15 DUF3106 PF11304.3 KXX76965.1 - 4 7.9 8.2 1.4 9.4 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF4282 PF14110.1 KXX76966.1 - 1.1 9.5 8.5 9.6 6.4 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) DUF805 PF05656.9 KXX76966.1 - 7.5 6.4 9.0 1.8 8.3 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) NAD_binding_8 PF13450.1 KXX76967.1 - 1.2e-15 57.2 0.2 3.9e-15 55.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KXX76967.1 - 5.7e-07 28.9 0.0 1.1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KXX76967.1 - 2.9e-06 26.4 1.5 1.3e-05 24.2 1.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX76967.1 - 3e-05 22.6 0.6 4.3e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KXX76967.1 - 5.1e-05 22.2 2.1 8.5e-05 21.5 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KXX76967.1 - 0.00017 20.7 0.5 0.00025 20.2 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX76967.1 - 0.00036 20.4 0.1 0.0012 18.8 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX76967.1 - 0.00038 20.5 0.2 0.0044 17.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX76967.1 - 0.00097 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX76967.1 - 0.0062 16.3 0.8 0.017 14.8 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KXX76967.1 - 0.026 13.4 0.1 0.049 12.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX76967.1 - 0.033 13.2 0.5 0.052 12.5 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KXX76967.1 - 0.039 14.3 0.3 0.078 13.3 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PHO4 PF01384.15 KXX76968.1 - 1.2e-109 365.9 16.5 1.5e-109 365.6 11.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family ALMT PF11744.3 KXX76968.1 - 3.2 6.2 15.3 5.8 5.4 10.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MFS_1 PF07690.11 KXX76971.1 - 1.3e-33 116.2 43.5 1.3e-33 116.2 30.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX76971.1 - 1.1e-11 44.0 10.2 1.1e-11 44.0 7.1 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 KXX76972.1 - 1.6e-50 171.9 0.0 1.7e-34 119.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.17 KXX76973.1 - 8.1e-49 166.2 8.4 1.3e-48 165.6 5.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KXX76973.1 - 0.0001 22.7 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Defensin_3 PF08131.6 KXX76974.1 - 0.14 12.1 0.3 0.14 12.1 0.2 2.2 3 0 0 3 3 3 0 Defensin-like peptide family SGL PF08450.7 KXX76975.1 - 0.0049 16.2 0.0 0.09 12.1 0.0 2.7 2 2 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region FAD_binding_3 PF01494.14 KXX76977.1 - 1.6e-14 53.7 0.3 4.5e-14 52.2 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX76977.1 - 0.00022 21.1 1.8 0.00059 19.8 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX76977.1 - 0.0039 16.9 0.3 0.0075 16.0 0.2 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 KXX76977.1 - 0.004 16.1 2.4 0.009 14.9 0.8 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 KXX76977.1 - 0.0068 15.2 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KXX76977.1 - 0.018 13.9 0.3 0.19 10.6 0.5 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX76977.1 - 0.031 14.1 0.4 0.051 13.4 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX76977.1 - 1.1 7.9 6.7 0.43 9.3 2.8 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KXX76978.1 - 6.1e-24 85.2 0.0 6.4e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX76978.1 - 1.8e-14 54.1 0.0 1.2e-11 44.8 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KXX76978.1 - 8e-13 47.4 1.8 2.6e-12 45.7 0.2 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KXX76978.1 - 9.1e-13 47.8 0.1 6.7e-10 38.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KXX76978.1 - 6.3e-05 22.1 0.0 0.00041 19.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX76978.1 - 6.9e-05 23.1 0.5 0.07 13.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX76978.1 - 0.0007 19.5 0.0 0.0056 16.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX76978.1 - 0.0011 18.7 2.5 1.9 8.2 0.2 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KXX76978.1 - 0.0022 17.1 0.1 0.013 14.6 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KXX76978.1 - 0.0038 16.9 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KXX76978.1 - 0.0078 15.1 4.5 0.77 8.6 0.3 3.4 3 1 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KXX76978.1 - 0.011 15.8 0.1 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KXX76978.1 - 0.027 12.9 1.4 0.68 8.3 0.1 3.2 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.17 KXX76978.1 - 0.064 12.1 2.6 9.8 4.9 0.1 3.4 4 0 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KXX76978.1 - 0.066 12.0 2.5 2.3 6.9 0.9 2.9 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KXX76978.1 - 0.11 11.3 0.2 0.25 10.2 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 KXX76978.1 - 0.12 12.3 0.0 2.9 7.9 0.0 2.7 3 0 0 3 3 2 0 TrkA-N domain HTH_38 PF13936.1 KXX76979.1 - 0.01 15.3 0.1 0.098 12.2 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain PsbH PF00737.15 KXX76980.1 - 0.0033 16.9 1.1 0.35 10.4 0.0 2.7 2 1 1 3 3 3 2 Photosystem II 10 kDa phosphoprotein Peripla_BP_6 PF13458.1 KXX76981.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Thymidylat_synt PF00303.14 KXX76982.1 - 4.5e-115 383.2 0.0 5.1e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase ketoacyl-synt PF00109.21 KXX76983.1 - 4.1e-79 265.6 0.0 9.6e-79 264.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX76983.1 - 7.2e-51 173.4 0.0 1.3e-50 172.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KXX76983.1 - 4.6e-46 156.7 0.0 1.1e-45 155.5 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KXX76983.1 - 3.2e-44 151.2 0.0 5.1e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX76983.1 - 5.7e-40 136.9 0.2 2.7e-39 134.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX76983.1 - 1.1e-29 102.6 0.1 2.8e-29 101.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KXX76983.1 - 7.1e-07 29.3 0.3 1.5e-05 25.1 0.0 3.0 3 0 0 3 3 3 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KXX76983.1 - 0.011 14.6 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain FAD_binding_6 PF00970.19 KXX76984.1 - 1.3e-08 34.8 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KXX76984.1 - 1.8e-08 34.6 0.0 2.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 KXX76984.1 - 5.4e-06 26.9 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 KXX76984.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Protoglobin Glycos_transf_1 PF00534.15 KXX76985.1 - 8.5e-24 83.8 0.0 2.3e-23 82.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KXX76985.1 - 3.4e-10 40.2 0.0 1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KXX76985.1 - 0.00022 21.4 0.0 0.00064 19.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Haem_bd PF14376.1 KXX76985.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Haem-binding domain Sec10 PF07393.6 KXX76986.1 - 4.5e-228 758.9 4.9 5.5e-228 758.7 3.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 BTG PF07742.7 KXX76986.1 - 0.15 11.5 0.4 10 5.6 0.0 3.3 2 1 1 3 3 3 0 BTG family K_channel_TID PF07941.6 KXX76986.1 - 0.16 12.2 5.3 0.44 10.8 3.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.27 KXX76987.1 - 3.7e-09 36.1 2.6 3.2e-06 26.8 0.1 4.4 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF2415 PF10313.4 KXX76987.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) RRN3 PF05327.6 KXX76987.1 - 7.8 4.4 9.7 11 4.0 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Chitin_synth_2 PF03142.10 KXX76989.1 - 1.9e-294 976.9 0.8 2e-294 976.9 0.1 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KXX76989.1 - 1.1e-18 67.6 3.7 5.8e-18 65.2 2.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX76989.1 - 1.3e-14 54.5 0.0 2.2e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KXX76989.1 - 7.5e-13 48.0 0.0 5.5e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KXX76989.1 - 0.00016 20.9 0.0 0.0009 18.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX76989.1 - 0.033 13.8 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 MFS_2 PF13347.1 KXX76990.1 - 4.2e-12 45.1 12.9 4.2e-12 45.1 9.0 2.1 3 0 0 3 3 3 1 MFS/sugar transport protein HisG PF01634.13 KXX76991.1 - 2.4e-48 163.7 0.3 3.8e-47 159.8 0.2 2.2 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KXX76991.1 - 7e-29 99.5 0.3 1.4e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HLH PF00010.21 KXX76992.1 - 2.9e-18 65.2 0.0 6.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Proteasome PF00227.21 KXX76993.1 - 4.5e-50 169.5 0.3 5.4e-50 169.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KXX76993.1 - 0.028 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Prenyltransf PF01255.14 KXX76994.1 - 2.5e-08 33.3 0.0 3.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Met_10 PF02475.11 KXX76995.1 - 7.2e-75 250.9 0.0 9.5e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KXX76995.1 - 0.0043 17.0 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX76995.1 - 0.0079 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RNB PF00773.14 KXX76996.1 - 6.1e-61 206.4 0.0 9.2e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain Sel1 PF08238.7 KXX76997.1 - 5.3e-38 128.6 29.6 5.1e-05 23.7 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat CD99L2 PF12301.3 KXX76997.1 - 0.0072 16.0 0.6 0.015 14.9 0.4 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 MSC PF09402.5 KXX76998.1 - 1.1e-103 346.4 0.0 1.4e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KXX76998.1 - 6.4e-18 64.0 0.4 2.4e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.6 KXX76998.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein DUF3350 PF11830.3 KXX76998.1 - 0.03 14.3 2.7 2.9 7.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) Peptidase_M22 PF00814.20 KXX76999.1 - 5.7e-46 157.1 0.0 2.2e-16 60.1 0.0 4.2 4 1 0 4 4 4 4 Glycoprotease family UPF0016 PF01169.14 KXX77000.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 DUF1752 PF08550.5 KXX77001.1 - 2e-08 33.6 5.8 3.1e-08 33.0 2.9 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Spt5_N PF11942.3 KXX77001.1 - 0.017 15.6 13.2 0.031 14.8 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 KXX77001.1 - 0.15 12.4 15.2 1.2 9.5 1.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KXX77001.1 - 2.3 7.7 7.6 1.8 8.0 0.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin TFIIA PF03153.8 KXX77001.1 - 4.1 7.1 9.0 17 5.1 6.2 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4611 PF15387.1 KXX77001.1 - 4.3 7.5 7.4 4.2 7.5 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ATP-grasp_4 PF13535.1 KXX77002.1 - 3.1e-20 72.6 0.0 9.8e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KXX77002.1 - 8.5e-05 21.4 0.0 0.0093 14.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX77002.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KXX77002.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Ferric_reduct PF01794.14 KXX77003.1 - 1.5e-18 67.1 17.8 5.5e-18 65.2 12.3 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KXX77003.1 - 3.8e-05 23.6 0.0 0.36 10.7 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KXX77003.1 - 0.00022 21.7 0.0 0.00064 20.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 KXX77003.1 - 0.00036 20.3 0.0 0.58 10.0 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain Hist_deacetyl PF00850.14 KXX77003.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Methyltransf_31 PF13847.1 KXX77004.1 - 1.3e-20 73.5 0.0 2.6e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77004.1 - 3.4e-16 59.8 0.0 1.1e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77004.1 - 1.8e-12 47.5 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77004.1 - 2.1e-12 47.3 0.0 5.5e-12 46.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX77004.1 - 4.8e-08 32.8 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77004.1 - 2.3e-07 31.1 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77004.1 - 3.7e-07 29.5 0.0 7.6e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX77004.1 - 1.5e-06 27.6 0.0 3.8e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX77004.1 - 1.1e-05 25.4 0.0 3.7e-05 23.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX77004.1 - 4.2e-05 22.6 0.0 8.8e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 KXX77004.1 - 0.00048 19.2 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 KXX77004.1 - 0.00081 18.8 0.0 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 KXX77004.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KXX77004.1 - 0.0051 16.3 0.0 0.02 14.4 0.0 1.9 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 KXX77004.1 - 0.0052 15.8 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 KXX77004.1 - 0.0059 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 KXX77004.1 - 0.0067 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX77004.1 - 0.0095 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.12 KXX77004.1 - 0.04 12.9 0.0 0.068 12.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 KXX77004.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HTH_23 PF13384.1 KXX77004.1 - 0.071 12.7 0.0 0.44 10.2 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain PTR2 PF00854.16 KXX77005.1 - 1.7e-23 83.0 4.8 3.7e-16 58.8 1.2 2.3 1 1 0 2 2 2 2 POT family Claudin_2 PF13903.1 KXX77005.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.8 4 1 1 5 5 5 0 PMP-22/EMP/MP20/Claudin tight junction Aa_trans PF01490.13 KXX77006.1 - 1.7e-76 257.3 29.8 2e-76 257.1 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lyase_1 PF00206.15 KXX77007.1 - 1.9e-88 296.6 0.0 2.5e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KXX77007.1 - 2.3e-24 85.2 0.6 6.7e-24 83.7 0.1 2.1 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF1996 PF09362.5 KXX77008.1 - 2.5e-90 302.2 0.8 2.9e-90 302.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PALP PF00291.20 KXX77009.1 - 9.5e-22 77.5 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.16 KXX77010.1 - 2.2e-36 125.4 0.0 1.6e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Formyl_trans_N PF00551.14 KXX77010.1 - 3.4e-25 88.6 0.0 6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KXX77010.1 - 2e-14 53.4 0.0 4.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.14 KXX77010.1 - 0.0016 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DegT_DnrJ_EryC1 PF01041.12 KXX77011.1 - 1e-103 347.2 0.0 1.1e-103 347.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KXX77011.1 - 3.2e-05 23.0 0.0 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX77011.1 - 0.0055 15.5 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KXX77011.1 - 0.0061 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TRP PF06011.7 KXX77012.1 - 6.2e-148 493.0 30.2 7.6e-148 492.7 21.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX77012.1 - 4.8e-40 136.8 0.1 7.6e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 KXX77012.1 - 0.056 13.6 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 ML domain UPF0183 PF03676.9 KXX77012.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) zf-DHHC PF01529.15 KXX77012.1 - 1.1 8.6 8.6 3.5e+02 0.4 5.9 2.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase Caudal_act PF04731.7 KXX77013.1 - 0.087 13.1 3.2 0.12 12.6 2.2 1.2 1 0 0 1 1 1 0 Caudal like protein activation region UCH PF00443.24 KXX77015.1 - 3.4e-40 137.8 0.0 5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KXX77015.1 - 1.9e-23 82.3 16.6 2.6e-20 72.2 0.9 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KXX77015.1 - 1.2e-18 67.5 0.0 2.3e-14 53.5 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KXX77015.1 - 1.4e-18 66.1 0.1 1.5e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Stc1 PF12898.2 KXX77015.1 - 0.14 12.2 9.4 3.6 7.6 0.9 3.8 2 2 1 3 3 3 0 Stc1 domain NifU_N PF01592.11 KXX77016.1 - 7.2e-53 177.8 0.0 9.2e-53 177.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain adh_short PF00106.20 KXX77017.1 - 2.9e-19 69.5 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX77017.1 - 6.9e-13 48.9 0.0 9.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX77017.1 - 7.3e-07 29.3 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KXX77017.1 - 0.0074 15.4 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KXX77017.1 - 0.0076 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Ank_2 PF12796.2 KXX77018.1 - 1.9e-13 50.5 0.0 2.4e-07 30.9 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77018.1 - 4.7e-10 38.7 6.3 0.03 14.1 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KXX77018.1 - 1e-07 32.2 1.8 0.071 13.6 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77018.1 - 4.6e-05 23.2 3.1 5.5 7.5 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 KXX77018.1 - 0.0021 18.2 3.4 0.99 9.7 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) HORMA PF02301.13 KXX77019.1 - 1.4e-41 142.2 0.0 1.7e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PP_M1 PF03012.9 KXX77019.1 - 0.069 12.4 0.5 0.093 12.0 0.3 1.1 1 0 0 1 1 1 0 Phosphoprotein DUF2411 PF10304.4 KXX77019.1 - 0.098 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Med21 PF11221.3 KXX77019.1 - 0.25 11.3 2.7 0.43 10.5 1.9 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Beta-lactamase PF00144.19 KXX77020.1 - 2.2e-38 132.0 0.1 4.5e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase Cauli_VI PF01693.11 KXX77023.1 - 3.3e-33 113.4 12.0 1.8e-17 63.0 1.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KXX77023.1 - 9.6e-28 97.1 0.0 1.6e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KXX77023.1 - 0.17 11.7 0.2 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like Peptidase_C14 PF00656.17 KXX77024.1 - 4.7e-65 219.7 0.0 6.1e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Clr5 PF14420.1 KXX77024.1 - 8e-19 67.2 1.5 1.6e-18 66.3 1.0 1.5 1 0 0 1 1 1 1 Clr5 domain DUF4570 PF15134.1 KXX77024.1 - 0.017 14.9 1.0 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) AAA_31 PF13614.1 KXX77024.1 - 0.16 11.9 0.1 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 KXX77025.1 - 5.3e-65 219.1 0.0 9.6e-65 218.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KXX77025.1 - 1.2e-26 92.0 2.2 6.6e-14 51.3 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KXX77025.1 - 6.9e-15 54.6 0.0 2.4e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POR PF01558.13 KXX77025.1 - 0.046 13.6 0.2 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase SIR2 PF02146.12 KXX77026.1 - 2.1e-27 96.0 0.0 5.3e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Sir2 family FF PF01846.14 KXX77027.1 - 5e-51 170.4 7.3 2.9e-14 52.7 0.1 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.21 KXX77027.1 - 1.9e-18 65.9 15.0 8e-10 38.3 2.8 2.6 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 KXX77028.1 - 3.5e-34 118.0 0.0 2.8e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX77028.1 - 1.4e-14 54.7 12.1 3.5e-05 23.9 0.1 4.8 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 KXX77028.1 - 2.6e-09 36.6 1.7 0.016 14.4 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KXX77028.1 - 1.4e-07 30.9 0.1 1.2 8.1 0.0 4.4 5 0 0 5 5 5 2 AAA ATPase domain RLI PF04068.10 KXX77028.1 - 2.4e-07 30.2 1.7 8.1e-07 28.5 1.2 2.0 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_17 PF13207.1 KXX77028.1 - 6.5e-07 30.1 0.2 0.033 15.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KXX77028.1 - 3.8e-06 27.1 0.1 0.011 15.8 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KXX77028.1 - 4.2e-06 27.0 0.1 0.13 12.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX77028.1 - 1.8e-05 24.8 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KXX77028.1 - 4.9e-05 22.7 0.5 0.043 13.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KXX77028.1 - 0.00024 20.3 0.0 0.75 8.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Fer4 PF00037.22 KXX77028.1 - 0.00026 20.4 1.8 0.00026 20.4 1.3 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_23 PF13476.1 KXX77028.1 - 0.00033 21.0 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KXX77028.1 - 0.00038 20.1 1.7 0.039 13.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KXX77028.1 - 0.00042 20.3 0.3 0.48 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KXX77028.1 - 0.00066 19.8 0.1 0.29 11.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 KXX77028.1 - 0.00096 18.7 0.3 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 VirE PF05272.6 KXX77028.1 - 0.0014 18.1 0.1 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E SRP54 PF00448.17 KXX77028.1 - 0.0016 17.9 3.2 0.041 13.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 KXX77028.1 - 0.003 17.2 2.9 0.19 11.4 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KXX77028.1 - 0.0033 17.2 0.1 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KXX77028.1 - 0.004 16.5 0.3 1.3 8.3 0.0 2.8 3 0 0 3 3 3 1 Thymidylate kinase Fer4_10 PF13237.1 KXX77028.1 - 0.0054 16.4 0.3 0.0054 16.4 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 KXX77028.1 - 0.0059 16.5 0.7 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX77028.1 - 0.0059 16.3 0.3 0.3 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KXX77028.1 - 0.0077 15.6 0.1 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KXX77028.1 - 0.013 14.0 0.0 0.013 14.0 0.0 2.0 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 KXX77028.1 - 0.015 14.0 0.1 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fer4_21 PF14697.1 KXX77028.1 - 0.018 14.8 8.8 0.06 13.2 6.2 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Miro PF08477.8 KXX77028.1 - 0.019 15.4 0.1 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 KXX77028.1 - 0.032 13.1 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KXX77028.1 - 0.039 13.5 0.2 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KXX77028.1 - 0.048 13.5 0.0 7.8 6.5 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 KXX77028.1 - 0.051 14.3 3.3 0.11 13.1 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 KXX77028.1 - 0.068 13.4 9.7 0.23 11.7 6.8 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain T2SE PF00437.15 KXX77028.1 - 0.18 10.6 0.5 2.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein PduV-EutP PF10662.4 KXX77028.1 - 0.26 10.7 3.1 0.29 10.6 0.1 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KXX77028.1 - 0.28 11.0 2.1 19 5.1 0.0 3.2 2 2 1 3 3 2 0 AAA domain NTPase_1 PF03266.10 KXX77028.1 - 0.32 10.6 3.2 5.7 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase Fer4_17 PF13534.1 KXX77028.1 - 0.44 10.9 5.7 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 KXX77028.1 - 0.51 10.7 10.4 0.07 13.5 1.4 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 KXX77028.1 - 0.67 9.9 8.9 0.033 14.0 1.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.1 KXX77028.1 - 0.67 9.4 2.3 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_15 PF13459.1 KXX77028.1 - 0.74 10.4 4.3 0.34 11.5 0.5 2.3 2 0 0 2 2 1 0 4Fe-4S single cluster domain Fer4_8 PF13183.1 KXX77028.1 - 0.74 9.8 9.6 0.59 10.1 1.4 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KXX77028.1 - 6.9 6.8 8.9 0.76 9.8 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain SLD3 PF08639.5 KXX77029.1 - 1.8e-132 442.5 3.3 1.8e-132 442.5 2.3 2.0 3 0 0 3 3 3 1 DNA replication regulator SLD3 Trs65 PF12735.2 KXX77030.1 - 5.6e-72 242.6 0.0 8.7e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Homeobox PF00046.24 KXX77031.1 - 7.8e-16 57.4 0.8 2e-15 56.1 0.5 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KXX77031.1 - 2.1e-05 24.1 0.1 4.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.20 KXX77032.1 - 1.8e-68 230.5 0.0 7.9e-68 228.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77032.1 - 3.5e-37 127.8 0.0 6e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX77032.1 - 8.8e-07 28.1 0.0 2.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX77032.1 - 0.022 14.5 0.1 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KXX77032.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3500 PF12006.3 KXX77033.1 - 4.2e-103 344.5 0.0 4.9e-103 344.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Med16 PF11635.3 KXX77034.1 - 8.2e-128 427.4 0.0 1.1e-127 427.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 tRNA-synt_1g PF09334.6 KXX77035.1 - 7.9e-134 446.1 0.0 1e-133 445.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KXX77035.1 - 4.6e-05 21.6 0.1 0.00086 17.4 0.0 2.4 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Glyco_transf_34 PF05637.7 KXX77036.1 - 1.7e-66 224.1 0.3 2.2e-66 223.7 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KXX77036.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_16 PF00722.16 KXX77037.1 - 6.2e-08 32.1 0.2 5.6e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_M22 PF00814.20 KXX77038.1 - 5.7e-46 157.1 0.0 2.2e-16 60.1 0.0 4.2 4 1 0 4 4 4 4 Glycoprotease family UPF0016 PF01169.14 KXX77039.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 ABM PF03992.11 KXX77040.1 - 1.3e-05 25.1 0.0 0.02 14.8 0.0 2.7 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AIP3 PF03915.8 KXX77041.1 - 0.0024 16.8 8.8 0.0037 16.2 6.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4407 PF14362.1 KXX77041.1 - 0.0056 15.6 8.8 0.0095 14.9 6.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Abhydrolase_2 PF02230.11 KXX77041.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF4279 PF14106.1 KXX77041.1 - 0.052 13.4 0.1 0.43 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DUF3508 PF12018.3 KXX77041.1 - 0.32 9.9 5.1 0.18 10.7 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) GAS PF13851.1 KXX77041.1 - 0.8 8.8 12.9 0.53 9.4 2.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KXX77041.1 - 2.3 8.6 9.4 0.62 10.4 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Syntaxin_2 PF14523.1 KXX77041.1 - 3.2 7.8 9.4 68 3.5 5.8 2.9 1 1 1 2 2 2 0 Syntaxin-like protein HR1 PF02185.11 KXX77041.1 - 3.8 7.3 7.3 1.7 8.4 0.7 3.4 2 2 0 2 2 2 0 Hr1 repeat APG6 PF04111.7 KXX77041.1 - 4 6.4 16.2 1.3 8.0 6.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 OmpH PF03938.9 KXX77041.1 - 8.2 6.3 12.6 0.64 9.9 4.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Abhydrolase_2 PF02230.11 KXX77042.1 - 7.1e-10 38.6 0.1 5.2e-05 22.7 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX77042.1 - 0.0012 18.7 0.5 0.0018 18.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX77042.1 - 0.0016 18.2 0.1 0.0026 17.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX77042.1 - 0.037 13.2 0.1 0.052 12.7 0.1 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Shal-type PF11601.3 KXX77042.1 - 0.041 13.4 0.4 0.084 12.4 0.3 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Abhydrolase_3 PF07859.8 KXX77042.1 - 0.062 12.8 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1752 PF08550.5 KXX77043.1 - 2e-08 33.6 5.8 3.1e-08 33.0 2.9 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Spt5_N PF11942.3 KXX77043.1 - 0.017 15.6 13.2 0.031 14.8 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 KXX77043.1 - 0.15 12.4 15.2 1.2 9.5 1.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KXX77043.1 - 2.3 7.7 7.6 1.8 8.0 0.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin TFIIA PF03153.8 KXX77043.1 - 4.1 7.1 9.0 17 5.1 6.2 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4611 PF15387.1 KXX77043.1 - 4.3 7.5 7.4 4.2 7.5 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Proteasome PF00227.21 KXX77044.1 - 4.5e-50 169.5 0.3 5.4e-50 169.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KXX77044.1 - 0.028 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) zf-CCHC PF00098.18 KXX77045.1 - 3.1e-38 127.9 87.8 3.1e-07 29.9 1.0 12.0 12 0 0 12 12 12 10 Zinc knuckle zf-CCHC_6 PF15288.1 KXX77045.1 - 2e-05 24.1 66.7 0.065 12.9 0.7 9.8 8 2 2 10 10 10 6 Zinc knuckle zf-CCHC_4 PF14392.1 KXX77045.1 - 2.1e-05 24.0 49.0 0.1 12.2 0.5 9.0 8 1 1 9 9 9 6 Zinc knuckle zf-CCHC_3 PF13917.1 KXX77045.1 - 0.014 15.1 1.9 0.014 15.1 1.3 8.9 5 3 5 10 10 10 0 Zinc knuckle FA_desaturase PF00487.19 KXX77046.1 - 7.1e-34 117.4 21.2 9.8e-34 116.9 14.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KXX77046.1 - 1.6e-19 68.8 0.2 3.1e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Vac7 PF12751.2 KXX77047.1 - 6.1e-122 407.2 4.0 6.1e-122 407.2 2.8 2.2 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Acetyltransf_2 PF00797.12 KXX77048.1 - 2.2e-32 112.5 0.0 6.7e-32 110.9 0.0 1.7 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 KXX77048.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily LMBR1 PF04791.11 KXX77049.1 - 1.1 7.8 9.0 1.7 7.1 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Z1 PF10593.4 KXX77049.1 - 4 6.5 9.1 0.44 9.7 3.1 1.7 2 0 0 2 2 2 0 Z1 domain V_ATPase_I PF01496.14 KXX77049.1 - 6.7 4.4 16.9 3.4 5.4 8.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ribosomal_L7Ae PF01248.21 KXX77050.1 - 3.8e-24 84.0 0.0 4.3e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 KXX77051.1 - 4.8e-31 107.2 0.1 6.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Proteasome PF00227.21 KXX77053.1 - 2.6e-47 160.5 0.0 3.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX77053.1 - 1.9e-13 49.4 0.1 1.9e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2011 PF09428.5 KXX77054.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) UPF0546 PF10639.4 KXX77055.1 - 1.6e-36 124.5 0.1 2.5e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KXX77055.1 - 0.0021 18.0 5.2 0.016 15.2 3.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family DUF1211 PF06736.6 KXX77055.1 - 0.094 12.8 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) C2 PF00168.25 KXX77056.1 - 1e-11 44.5 0.1 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 KXX77056.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein RrnaAD PF00398.15 KXX77057.1 - 1.4e-51 175.0 0.0 1.9e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KXX77057.1 - 7e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77057.1 - 5.5e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KXX77057.1 - 8.6e-05 22.2 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KXX77057.1 - 0.00048 19.5 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KXX77057.1 - 0.00067 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KXX77057.1 - 0.0024 17.5 0.0 0.0057 16.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KXX77057.1 - 0.0042 16.6 0.1 0.01 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 KXX77057.1 - 0.017 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KXX77057.1 - 0.038 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KXX77057.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UTP15_C PF09384.5 KXX77059.1 - 4.2e-47 159.5 0.0 6.2e-47 159.0 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KXX77059.1 - 2.7e-26 90.4 3.6 3.5e-08 33.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-MIZ PF02891.15 KXX77060.1 - 5.3e-09 35.4 9.9 5.1e-08 32.3 1.0 2.6 1 1 1 2 2 2 2 MIZ/SP-RING zinc finger Arrestin_N PF00339.24 KXX77061.1 - 1.3e-15 57.5 0.0 2.9e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain IncA PF04156.9 KXX77062.1 - 0.00066 19.3 37.2 0.023 14.3 0.8 3.4 3 0 0 3 3 3 3 IncA protein DUF1664 PF07889.7 KXX77062.1 - 0.011 15.4 20.6 0.12 12.1 2.7 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 KXX77062.1 - 4.7 6.5 17.3 0.16 11.3 2.5 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) SIS PF01380.17 KXX77063.1 - 8e-13 48.1 0.3 2.7e-12 46.4 0.0 2.0 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KXX77063.1 - 0.0025 17.5 0.0 0.043 13.5 0.1 2.2 1 1 1 2 2 2 1 SIS domain DUF2373 PF10180.4 KXX77064.1 - 5.2e-22 77.1 2.3 5.3e-22 77.1 0.3 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) MFS_1 PF07690.11 KXX77065.1 - 1.8e-35 122.3 50.7 1.8e-35 122.3 35.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX77065.1 - 7e-12 44.3 23.2 2e-11 42.8 16.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glycophorin_A PF01102.13 KXX77065.1 - 0.32 10.7 1.9 20 4.9 0.0 3.1 3 0 0 3 3 3 0 Glycophorin A Peptidase_U4 PF03419.8 KXX77065.1 - 0.99 8.4 9.0 0.071 12.1 2.3 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA B3_4 PF03483.12 KXX77066.1 - 3.8e-25 88.3 0.0 6.3e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KXX77066.1 - 9.7e-15 54.1 0.0 1.2e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 KXX77066.1 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein PAP2 PF01569.16 KXX77067.1 - 2.9e-17 62.5 3.6 2.9e-17 62.5 2.5 2.2 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.1 KXX77067.1 - 0.19 12.0 2.4 0.39 11.0 0.8 2.3 1 1 1 2 2 2 0 PAP2 superfamily C-terminal JmjC PF02373.17 KXX77068.1 - 6.4e-37 126.2 0.8 1.5e-36 125.0 0.5 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 KXX77068.1 - 6e-21 74.4 3.7 6e-21 74.4 2.6 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KXX77068.1 - 6.3e-21 74.4 4.0 1.2e-20 73.5 2.8 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 KXX77068.1 - 7.3e-14 51.0 2.3 1.4e-13 50.1 1.6 1.5 1 0 0 1 1 1 1 jmjN domain ThiF PF00899.16 KXX77069.1 - 2.2e-41 140.8 0.1 4.9e-41 139.7 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KXX77069.1 - 1.7e-30 104.4 2.4 2.8e-30 103.6 0.5 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KXX77069.1 - 2.8e-21 75.3 1.2 4.8e-21 74.6 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KXX77069.1 - 4.8e-19 67.4 1.1 4.8e-19 67.4 0.8 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KXX77069.1 - 0.00032 20.9 1.0 0.00056 20.1 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KXX77069.1 - 0.0033 17.5 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KXX77069.1 - 0.037 14.4 0.1 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MoeZ_MoeB PF05237.8 KXX77069.1 - 0.058 12.9 0.7 0.97 9.0 0.0 2.6 2 0 0 2 2 2 0 MoeZ/MoeB domain adh_short_C2 PF13561.1 KXX77070.1 - 4.6e-26 92.0 0.0 5.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX77070.1 - 8.3e-26 90.8 0.3 1.1e-25 90.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77070.1 - 7.1e-07 29.0 0.2 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX77070.1 - 2.1e-06 27.3 0.0 5.6e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX77070.1 - 1.2e-05 25.4 0.8 0.00011 22.2 0.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX77070.1 - 0.00022 20.2 0.0 0.00028 19.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KXX77070.1 - 0.0042 17.4 0.0 0.0094 16.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KXX77070.1 - 0.0056 15.6 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Shikimate_DH PF01488.15 KXX77070.1 - 0.008 16.2 0.1 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KXX77070.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KXX77070.1 - 0.036 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 KXX77070.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CinA PF02464.12 KXX77071.1 - 3.7e-42 143.3 0.0 4.4e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein eIF-5a PF01287.15 KXX77071.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold ArgK PF03308.11 KXX77071.1 - 0.44 9.2 3.1 0.64 8.7 2.2 1.3 1 0 0 1 1 1 0 ArgK protein HET PF06985.6 KXX77072.1 - 2.4e-21 76.3 0.0 4.9e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4440 PF14534.1 KXX77073.1 - 0.00093 19.3 0.1 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MFS_1 PF07690.11 KXX77074.1 - 7.5e-38 130.1 25.5 7.5e-38 130.1 17.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77074.1 - 1.2e-18 66.9 0.8 1.2e-18 66.9 0.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KXX77074.1 - 0.033 12.2 1.1 0.27 9.2 0.7 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.6 KXX77076.1 - 4.9e-23 81.8 0.0 8.9e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.16 KXX77078.1 - 6.4e-136 453.4 38.5 7.9e-136 453.1 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX77078.1 - 1.2e-35 122.8 42.8 1.6e-35 122.4 29.7 1.2 1 0 0 1 1 1 1 Amino acid permease Defensin_big PF14862.1 KXX77078.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Big defensin DUF2077 PF09850.4 KXX77078.1 - 1.4 8.2 3.1 3.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) adh_short PF00106.20 KXX77079.1 - 2.7e-13 50.1 0.2 6.3e-13 48.9 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77079.1 - 1.1e-05 25.1 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KXX77079.1 - 0.067 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 KXX77080.1 - 0.0086 14.7 1.5 0.014 14.0 1.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2419 PF10343.4 KXX77081.1 - 9e-135 448.4 0.0 1.1e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KXX77081.1 - 0.16 11.8 0.9 0.3 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) DNA_pol_delta_4 PF04081.8 KXX77082.1 - 3.5e-32 111.3 1.9 4.2e-32 111.0 0.4 1.8 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 WD40 PF00400.27 KXX77083.1 - 3.3e-21 74.3 12.8 6.9e-08 32.0 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 KXX77083.1 - 4.3e-11 42.8 7.3 4.3e-11 42.8 5.0 1.8 2 0 0 2 2 2 1 Ribosomal L32p protein family PQQ_2 PF13360.1 KXX77083.1 - 0.00031 20.2 0.6 0.00077 18.9 0.4 1.7 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 KXX77083.1 - 0.00074 19.7 1.2 0.32 11.3 0.1 2.7 2 0 0 2 2 2 2 PQQ-like domain Hira PF07569.6 KXX77083.1 - 0.0021 17.3 0.7 0.049 12.8 0.0 2.6 3 0 0 3 3 3 1 TUP1-like enhancer of split Nup160 PF11715.3 KXX77083.1 - 0.0036 15.5 0.2 0.16 10.0 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 KXX77083.1 - 0.0048 16.6 0.1 0.31 10.7 0.0 3.0 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KXX77083.1 - 0.011 14.5 0.0 0.081 11.6 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like PolC_DP2 PF03833.8 KXX77083.1 - 0.017 12.8 0.5 0.023 12.3 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Abhydrolase_4 PF08386.5 KXX77083.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Cytochrom_D1 PF02239.11 KXX77083.1 - 0.042 12.1 0.1 0.16 10.2 0.1 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Nbas_N PF15492.1 KXX77083.1 - 0.052 12.6 0.2 5.8 5.9 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KXX77084.1 - 4.4e-113 376.9 1.0 5.3e-113 376.7 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KXX77084.1 - 8e-07 29.0 0.0 1.4e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KXX77084.1 - 1.4e-06 27.6 0.0 2.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KXX77084.1 - 2.5e-05 23.5 0.0 4.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KXX77084.1 - 3.6e-05 23.2 0.2 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KXX77084.1 - 0.00082 19.2 0.6 1.2 8.9 0.2 2.6 1 1 1 2 2 2 2 Dynamin family AAA_23 PF13476.1 KXX77084.1 - 0.0025 18.1 0.2 0.0036 17.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KXX77084.1 - 0.0031 17.0 0.0 0.0031 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KXX77084.1 - 0.0073 15.4 0.1 0.056 12.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KXX77084.1 - 0.0079 16.3 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KXX77084.1 - 0.011 15.9 0.7 0.02 15.2 0.4 1.7 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KXX77084.1 - 0.024 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KXX77084.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KXX77084.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KXX77084.1 - 0.045 12.6 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 KXX77084.1 - 0.059 12.7 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.1 KXX77084.1 - 0.15 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.2 KXX77085.1 - 5.7e-06 25.9 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF3639 PF12341.3 KXX77085.1 - 0.12 12.4 0.3 0.31 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) RabGAP-TBC PF00566.13 KXX77086.1 - 7.5e-46 156.3 0.0 1.2e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ISAV_HA PF06215.6 KXX77086.1 - 0.34 9.1 0.0 0.55 8.4 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Ribosomal_S26e PF01283.14 KXX77089.1 - 1.4e-51 173.5 9.6 1.6e-51 173.3 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 KXX77089.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 KXX77089.1 - 0.047 14.0 0.3 6.6 7.1 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 KXX77089.1 - 0.085 13.2 2.2 1.2 9.6 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain PepSY_2 PF13670.1 KXX77090.1 - 1.1 9.2 3.6 0.63 9.9 0.9 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Polysacc_deac_1 PF01522.16 KXX77091.1 - 1.7e-14 53.5 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Luciferase_cat PF10285.4 KXX77091.1 - 0.13 11.3 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain ubiquitin PF00240.18 KXX77092.1 - 1.4e-34 117.2 0.9 2.8e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KXX77092.1 - 7.9e-29 99.2 2.1 1.6e-28 98.2 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KXX77092.1 - 5.4e-20 70.8 0.7 1e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KXX77092.1 - 8.6e-06 25.9 0.5 4e-05 23.7 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KXX77092.1 - 0.00012 21.8 0.1 0.0002 21.1 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KXX77092.1 - 0.00073 19.4 0.7 0.0015 18.3 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KXX77092.1 - 0.0043 17.1 0.6 0.006 16.7 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KXX77092.1 - 0.046 13.7 0.6 0.081 12.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Stig1 PF04885.8 KXX77092.1 - 0.057 13.6 0.2 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Plexin_cytopl PF08337.7 KXX77092.1 - 0.085 11.1 2.8 1.6 6.9 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 KXX77092.1 - 0.094 12.5 0.5 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 IBR domain Fer2_3 PF13085.1 KXX77092.1 - 0.25 11.1 1.2 0.49 10.2 0.6 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_18 PF00704.23 KXX77093.1 - 3e-94 316.2 0.1 3.5e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 KXX77094.1 - 1.4e-09 38.1 0.0 4.1e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77094.1 - 3.2e-08 32.9 0.4 1.2e-07 31.2 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KXX77094.1 - 4e-07 29.6 0.0 1.6e-05 24.6 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KXX77094.1 - 7.2e-07 29.5 0.0 2.5e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77094.1 - 3.1e-06 27.2 0.0 2.6e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TPR_12 PF13424.1 KXX77095.1 - 7.4e-11 41.8 2.2 6e-06 26.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX77095.1 - 6.2e-07 28.7 5.5 0.13 12.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77095.1 - 3.2e-05 23.5 7.9 0.28 11.1 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77095.1 - 0.00022 20.8 4.1 0.37 10.4 0.8 2.8 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KXX77095.1 - 0.0004 19.8 3.2 0.83 9.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX77095.1 - 0.0008 19.4 2.3 0.58 10.3 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KXX77095.1 - 0.0014 18.2 0.4 0.049 13.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KXX77095.1 - 0.0035 17.2 1.1 11 6.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77095.1 - 0.013 16.1 1.9 2.3 8.9 0.3 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77095.1 - 0.028 14.7 0.6 0.65 10.3 0.2 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat lci PF12197.3 KXX77095.1 - 0.088 12.4 0.5 5.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein TPR_14 PF13428.1 KXX77095.1 - 0.47 11.2 5.3 51 4.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX77095.1 - 2.2 8.9 5.6 2.9 8.5 0.3 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4188 PF13826.1 KXX77096.1 - 1.3e-27 96.2 0.1 1.8e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 KXX77096.1 - 0.03 14.7 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF1330 PF07045.6 KXX77096.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) p450 PF00067.17 KXX77097.1 - 4.2e-52 177.2 0.0 6.9e-52 176.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 KXX77100.1 - 4.8e-06 26.2 7.5 8.5e-06 25.5 5.2 1.5 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 KXX77101.1 - 5.1e-47 160.2 50.8 1.2e-46 159.0 35.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX77101.1 - 6.3e-14 51.0 23.0 1.7e-13 49.7 16.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX77101.1 - 5.1e-11 41.8 10.8 5.1e-11 41.8 7.5 2.9 1 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 KXX77101.1 - 1.5e-05 23.6 3.0 1.5e-05 23.6 2.1 4.7 3 2 3 6 6 6 3 Vacuole effluxer Atg22 like DUF2844 PF11005.3 KXX77102.1 - 0.028 14.2 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) DUF1191 PF06697.7 KXX77103.1 - 3.6e-06 26.0 0.0 4.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 KXX77103.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 KXX77103.1 - 0.003 17.8 0.0 0.0053 17.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.2 KXX77103.1 - 0.0068 14.5 0.8 0.0086 14.2 0.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.1 KXX77103.1 - 0.0068 16.1 0.0 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF1049 PF06305.6 KXX77103.1 - 0.015 14.7 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Mid2 PF04478.7 KXX77103.1 - 0.048 13.0 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 KXX77103.1 - 0.079 12.6 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3753 PF12575.3 KXX77103.1 - 0.08 12.7 0.6 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF485 PF04341.7 KXX77103.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF829 PF05705.9 KXX77104.1 - 3.8e-23 82.4 0.2 1.1e-19 71.1 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Ribosomal_S2 PF00318.15 KXX77105.1 - 3.8e-48 163.5 0.0 1e-47 162.1 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S2 Med3 PF11593.3 KXX77105.1 - 1.9 7.6 5.1 2.4 7.3 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CBS PF00571.23 KXX77106.1 - 2.2e-41 139.3 11.2 8.5e-11 41.4 0.0 5.8 6 0 0 6 6 6 5 CBS domain PB1 PF00564.19 KXX77106.1 - 4.1e-09 35.9 0.0 1.7e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 PB1 domain PNRC PF15365.1 KXX77106.1 - 0.013 15.5 1.6 3.1 7.8 0.4 2.7 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Cpn60_TCP1 PF00118.19 KXX77107.1 - 3.8e-142 474.3 3.9 4.4e-142 474.1 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-H2C2 PF09337.5 KXX77108.1 - 2.3e-22 78.1 4.8 4.6e-22 77.1 3.4 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KXX77108.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KXX77108.1 - 0.00046 20.1 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KXX77108.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Imm47 PF15586.1 KXX77108.1 - 0.25 11.1 0.0 0.48 10.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 47 MIP-T3 PF10243.4 KXX77108.1 - 2.3 6.6 4.3 25 3.1 1.8 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ank_2 PF12796.2 KXX77109.1 - 3.1e-34 117.1 0.0 3.8e-12 46.3 0.0 6.6 5 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77109.1 - 4e-30 102.0 16.7 8.6e-05 22.1 0.0 10.1 10 1 1 11 11 11 6 Ankyrin repeat Ank_3 PF13606.1 KXX77109.1 - 1.2e-22 77.7 4.7 0.0048 17.0 0.0 9.2 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 KXX77109.1 - 9.7e-22 76.9 4.2 5.2e-06 26.8 0.0 7.4 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77109.1 - 4.1e-21 74.5 9.7 0.00035 20.7 0.1 9.2 8 1 1 9 9 9 5 Ankyrin repeats (many copies) F-box-like PF12937.2 KXX77109.1 - 1e-07 31.5 0.1 2.6e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX77109.1 - 0.0018 17.8 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.2 KXX77110.1 - 1.5e-34 118.1 0.9 5.6e-13 49.0 0.7 8.0 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77110.1 - 2.4e-29 99.6 13.2 2.4e-07 30.2 0.9 10.3 10 1 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.1 KXX77110.1 - 2.1e-20 70.7 13.3 6.1e-05 22.8 0.1 10.0 12 0 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.1 KXX77110.1 - 1.5e-18 66.7 8.2 0.00011 22.6 0.1 9.2 10 0 0 10 10 10 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77110.1 - 9.5e-17 60.6 13.7 8.8e-05 22.6 0.0 8.2 7 1 2 9 9 9 5 Ankyrin repeats (many copies) F-box-like PF12937.2 KXX77110.1 - 7.7e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like AAL_decarboxy PF03306.8 KXX77111.1 - 1.3e-73 246.7 0.2 1.5e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase zf-CCCH PF00642.19 KXX77112.1 - 8.2e-05 22.1 0.6 8.2e-05 22.1 0.4 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF501 PF04417.7 KXX77112.1 - 0.047 13.5 0.4 0.047 13.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FAA_hydrolase PF01557.13 KXX77113.1 - 6.3e-28 97.7 0.0 1.1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.3 KXX77113.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 87kDa Transposase DUF1237 PF06824.6 KXX77114.1 - 2.8e-181 602.7 0.0 3.3e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 KXX77115.1 - 1.2e-72 245.5 36.5 5.2e-72 243.4 25.3 1.9 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 K_channel_TID PF07941.6 KXX77115.1 - 0.082 13.1 2.4 0.23 11.7 1.6 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nop14 PF04147.7 KXX77115.1 - 0.082 10.8 16.2 0.11 10.3 11.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KXX77115.1 - 1.3 6.9 12.2 2 6.3 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 KXX77115.1 - 2.5 6.8 7.1 4.7 5.9 4.9 1.6 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 KXX77115.1 - 6.4 5.9 9.8 9.6 5.3 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein CytochromB561_N PF09786.4 KXX77115.1 - 6.8 5.0 7.9 9.7 4.5 5.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Fungal_trans PF04082.13 KXX77116.1 - 5.3e-37 127.1 0.0 1e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dna2 PF08696.6 KXX77116.1 - 0.013 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 PigN PF04987.9 KXX77117.1 - 2.3e-168 560.4 25.0 2.9e-168 560.0 17.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KXX77117.1 - 2.7e-11 43.4 0.6 3e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX77117.1 - 4.7e-07 29.2 0.1 8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KXX77117.1 - 0.00055 19.3 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily RNase_PH PF01138.16 KXX77118.1 - 2.8e-26 92.3 0.0 4.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Sec7 PF01369.15 KXX77119.1 - 5.7e-58 195.7 0.0 9e-58 195.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KXX77119.1 - 2.2e-18 66.2 0.1 4.5e-11 42.4 0.1 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Methyltransf_17 PF12692.2 KXX77119.1 - 0.15 11.7 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase DUF2454 PF10521.4 KXX77120.1 - 2.4e-67 226.8 0.0 5.8e-67 225.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 KXX77120.1 - 2.3e-23 82.7 0.6 6.2e-23 81.3 0.4 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KXX77120.1 - 1.7e-07 30.6 0.0 5.3e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KXX77120.1 - 0.026 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative RNA_pol_Rpb8 PF03870.10 KXX77121.1 - 1.8e-34 118.8 0.1 2.1e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 KXX77122.1 - 4.4e-96 321.8 0.0 7.1e-96 321.2 0.0 1.3 1 1 0 1 1 1 1 PAXNEB protein Prok-JAB PF14464.1 KXX77122.1 - 0.13 11.8 0.3 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain tRNA_int_endo PF01974.12 KXX77123.1 - 7.8e-15 54.4 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain zf-C3HC4_3 PF13920.1 KXX77124.1 - 1.8e-06 27.5 16.1 3e-06 26.7 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PhrC_PhrF PF11131.3 KXX77124.1 - 0.011 15.2 0.2 0.033 13.7 0.1 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling Glyco_hydro_47 PF01532.15 KXX77125.1 - 1.3e-167 558.1 0.0 1.5e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alpha_GJ PF03229.8 KXX77126.1 - 0.0085 16.4 6.3 0.022 15.1 4.3 1.7 1 0 0 1 1 1 1 Alphavirus glycoprotein J PDGLE PF13190.1 KXX77126.1 - 0.014 15.0 0.2 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 PDGLE domain Beta-APP PF03494.8 KXX77126.1 - 0.14 11.6 3.3 0.27 10.7 2.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) RRM_1 PF00076.17 KXX77127.1 - 3.6e-26 90.5 0.6 2.5e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77127.1 - 1.2e-16 60.4 0.2 7.8e-07 28.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77127.1 - 8.8e-15 54.3 0.1 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 KXX77127.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) ATP-synt_D PF01813.12 KXX77128.1 - 1.4e-41 142.2 2.5 5.1e-41 140.3 0.9 2.0 1 1 1 2 2 2 1 ATP synthase subunit D SYCE1 PF15233.1 KXX77128.1 - 0.024 14.5 3.0 0.049 13.5 2.0 1.6 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 MAAL_N PF05034.8 KXX77128.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus Herpes_BBRF1 PF04793.7 KXX77128.1 - 0.12 11.0 0.2 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 BRRF1-like protein DUF775 PF05603.7 KXX77129.1 - 1.2e-34 119.5 0.0 2.2e-34 118.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 KXX77130.1 - 1.1e-09 38.0 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GDA1_CD39 PF01150.12 KXX77131.1 - 3.4e-101 338.8 0.0 4.7e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Anp1 PF03452.9 KXX77132.1 - 1.3e-121 404.9 0.2 4.8e-121 403.0 0.0 1.8 2 0 0 2 2 2 1 Anp1 Syja_N PF02383.13 KXX77133.1 - 8.3e-89 297.5 0.0 2.1e-88 296.1 0.0 1.6 1 0 0 1 1 1 1 SacI homology domain MIP-T3 PF10243.4 KXX77135.1 - 0.32 9.4 15.3 0.55 8.6 10.6 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FSH1 PF03959.8 KXX77136.1 - 1.4e-32 112.9 0.0 4.4e-32 111.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX77136.1 - 3.9e-06 26.9 0.1 5.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BRO1 PF03097.13 KXX77137.1 - 7.1e-134 446.2 2.5 7.1e-134 446.2 1.7 2.7 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KXX77137.1 - 4.4e-92 308.1 19.7 4.4e-92 308.1 13.6 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.6 KXX77137.1 - 0.68 9.7 7.3 0.15 11.9 0.5 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1539 PF07560.6 KXX77137.1 - 1.4 8.8 8.2 1.6 8.6 0.0 3.6 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) DUF4407 PF14362.1 KXX77137.1 - 7.4 5.4 17.9 1.6 7.6 7.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3435 PF11917.3 KXX77138.1 - 2.5e-116 388.8 0.0 3.2e-116 388.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF2962 PF11176.3 KXX77138.1 - 0.048 13.2 6.1 2.4 7.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2962) Nse5 PF08691.5 KXX77138.1 - 0.13 10.7 0.1 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 OmpH PF03938.9 KXX77138.1 - 0.63 9.9 6.6 1 9.2 2.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2951 PF11166.3 KXX77138.1 - 1.1 9.1 7.1 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) TnpV PF14198.1 KXX77138.1 - 1.6 8.6 6.3 5.5 6.9 0.1 2.6 3 0 0 3 3 3 0 Transposon-encoded protein TnpV zf-C2H2_4 PF13894.1 KXX77140.1 - 1.2e-08 34.6 26.3 0.016 15.5 1.2 6.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KXX77140.1 - 7.4e-08 32.4 22.1 0.18 11.9 1.1 5.2 2 2 2 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KXX77140.1 - 9.5e-07 28.8 29.1 0.0065 16.7 1.2 6.3 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX77140.1 - 3.4e-05 23.9 24.0 0.016 15.4 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX77140.1 - 0.0002 21.4 22.6 0.00077 19.5 0.9 5.3 6 1 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX77140.1 - 0.00021 21.4 26.1 0.0011 19.0 0.5 5.8 5 1 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KXX77140.1 - 0.031 14.3 0.2 0.031 14.3 0.1 4.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KXX77140.1 - 1.3 8.7 16.6 0.79 9.4 1.0 4.1 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KXX77140.1 - 1.8 8.5 26.8 3.4 7.7 0.1 6.3 3 1 2 5 5 4 0 Zinc ribbon domain Ribosomal_L37ae PF01780.14 KXX77140.1 - 3.1 7.7 9.2 0.71 9.7 0.8 3.6 2 2 1 3 3 3 0 Ribosomal L37ae protein family zf-DBF PF07535.7 KXX77140.1 - 7.7 6.2 14.0 0.22 11.2 0.9 3.7 4 0 0 4 4 4 0 DBF zinc finger SET PF00856.23 KXX77141.1 - 1.3e-10 41.8 0.0 2.8e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 SET domain DUF3295 PF11702.3 KXX77143.1 - 2.6e-79 267.5 6.5 3.1e-79 267.2 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) TP2 PF01254.13 KXX77143.1 - 0.56 10.5 3.1 0.37 11.1 0.8 1.7 1 1 1 2 2 2 0 Nuclear transition protein 2 PAZ PF02170.17 KXX77147.1 - 3.6e-09 36.0 0.0 6.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 PAZ domain TYW3 PF02676.9 KXX77147.1 - 0.11 11.5 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase TYW3 BTB PF00651.26 KXX77147.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain PQQ PF01011.16 KXX77148.1 - 0.094 12.2 0.3 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat DUF2874 PF11396.3 KXX77149.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) HET PF06985.6 KXX77150.1 - 2e-14 53.9 0.0 4.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BCS1_N PF08740.6 KXX77151.1 - 6.8e-36 123.6 0.4 6.8e-36 123.6 0.3 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KXX77151.1 - 8.1e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX77151.1 - 0.0004 21.2 0.0 0.00097 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX77151.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77151.1 - 0.0021 18.0 0.0 0.0055 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KXX77151.1 - 0.0028 16.6 0.0 0.0069 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX77151.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KXX77151.1 - 0.021 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX77151.1 - 0.027 14.1 0.0 0.085 12.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX77151.1 - 0.029 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KXX77151.1 - 0.038 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.12 KXX77151.1 - 0.052 12.1 0.1 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase ABC_tran PF00005.22 KXX77151.1 - 0.053 13.8 0.1 0.69 10.2 0.0 2.6 3 1 0 3 3 2 0 ABC transporter Arch_ATPase PF01637.13 KXX77151.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Zot PF05707.7 KXX77151.1 - 0.056 12.9 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KXX77151.1 - 0.062 12.7 0.1 0.24 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain AAA_11 PF13086.1 KXX77151.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KXX77151.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 KXX77153.1 - 2.5e-06 26.8 0.0 4.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KXX77153.1 - 0.048 13.3 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KXX77153.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3435 PF11917.3 KXX77154.1 - 9.4e-121 403.4 0.0 1.2e-120 403.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3584 PF12128.3 KXX77154.1 - 0.013 12.9 2.7 0.021 12.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.3 KXX77154.1 - 0.017 14.8 1.1 0.017 14.8 0.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SOCS PF12610.3 KXX77154.1 - 0.059 13.7 5.6 1 9.7 2.4 2.8 2 0 0 2 2 2 0 Suppressor of cytokine signalling MCPsignal PF00015.16 KXX77154.1 - 0.062 12.8 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Metal_resist PF13801.1 KXX77154.1 - 0.47 10.4 4.5 1.3 9.0 3.1 1.7 1 0 0 1 1 1 0 Heavy-metal resistance zf-C2H2 PF00096.21 KXX77154.1 - 1.1 9.7 7.5 1.3 9.5 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4164 PF13747.1 KXX77154.1 - 7.4 6.7 12.8 0.29 11.3 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Acyltransferase PF01553.16 KXX77156.1 - 2.6e-30 104.5 0.0 3.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.4 KXX77157.1 - 3.1e-105 351.4 0.0 3.9e-105 351.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KXX77157.1 - 8.1e-49 166.0 0.0 1.6e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KXX77157.1 - 7.5e-06 25.6 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KXX77157.1 - 0.012 14.1 0.0 0.097 11.1 0.0 2.0 2 0 0 2 2 2 0 Transport protein Avl9 TATR PF03430.8 KXX77158.1 - 0.083 11.5 1.1 0.12 10.9 0.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PGC7_Stella PF15549.1 KXX77158.1 - 2.2 8.2 4.9 0.87 9.5 0.6 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain DTHCT PF08070.6 KXX77158.1 - 2.4 8.8 12.2 0.56 10.8 3.7 3.0 3 0 0 3 3 3 0 DTHCT (NUC029) region RCC1 PF00415.13 KXX77159.1 - 1.2e-58 195.0 0.0 9.4e-08 32.1 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KXX77159.1 - 1e-35 120.5 15.7 7.6e-07 28.5 0.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KXX77159.1 - 4.3e-12 45.4 0.1 8.4e-06 25.4 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat CBM_X PF06204.6 KXX77159.1 - 0.0018 17.6 1.3 0.21 11.0 0.0 2.6 2 0 0 2 2 2 2 Putative carbohydrate binding domain ORC6 PF05460.8 KXX77159.1 - 3 6.8 14.7 5.2 6.0 10.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_16 PF10294.4 KXX77161.1 - 2.5e-27 95.4 0.0 5e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KXX77161.1 - 9.8e-05 22.9 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX77161.1 - 0.00031 20.4 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77161.1 - 0.00091 19.6 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX77161.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KXX77161.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KXX77161.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPR_11 PF13414.1 KXX77162.1 - 1.3e-46 156.1 15.0 2.4e-19 68.7 0.4 5.7 4 3 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 KXX77162.1 - 3.9e-44 146.5 5.3 4.2e-07 29.3 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77162.1 - 1.8e-37 124.2 9.7 3.2e-07 29.7 0.0 8.3 7 1 2 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 KXX77162.1 - 3.3e-28 97.2 2.9 9.7e-28 95.7 1.1 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 KXX77162.1 - 2.7e-26 91.5 9.3 5.4e-07 30.1 0.1 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77162.1 - 8.1e-26 90.1 6.7 1.7e-07 31.4 0.0 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KXX77162.1 - 2.1e-20 70.8 0.7 0.00021 20.8 0.0 6.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77162.1 - 1.2e-18 66.8 8.6 3.5e-06 26.8 0.1 5.2 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KXX77162.1 - 1.3e-18 65.8 14.0 4.8e-05 23.6 0.0 8.4 4 3 5 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 KXX77162.1 - 8.5e-18 62.6 0.6 0.033 13.9 0.0 6.3 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KXX77162.1 - 2.4e-17 61.5 12.0 0.0039 17.2 0.1 7.5 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KXX77162.1 - 9.9e-16 57.3 6.1 0.0063 16.3 0.0 5.6 2 2 3 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 KXX77162.1 - 3.6e-15 55.8 2.0 2.3e-08 34.0 0.0 3.9 2 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KXX77162.1 - 1.1e-12 47.5 14.9 0.042 14.3 0.1 7.3 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 KXX77162.1 - 1.7e-07 30.6 2.8 0.025 13.6 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KXX77162.1 - 4.2e-06 26.5 7.8 1.6 8.7 0.1 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX77162.1 - 1.6e-05 24.6 1.9 4.8 7.1 0.0 5.3 5 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 KXX77162.1 - 4.7e-05 23.7 2.9 0.26 11.5 0.0 4.4 3 1 0 3 3 3 1 Bacterial transcriptional activator domain NARP1 PF12569.3 KXX77162.1 - 0.00015 20.6 1.6 0.08 11.6 0.2 3.3 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 KXX77162.1 - 0.00086 19.5 3.1 0.38 11.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 KXX77162.1 - 0.0022 17.7 0.2 3 7.6 0.0 3.5 3 2 1 4 4 3 1 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.4 KXX77162.1 - 0.0073 16.2 7.0 0.67 9.8 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KXX77162.1 - 0.013 14.2 0.3 0.03 13.0 0.0 1.7 2 1 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_20 PF14561.1 KXX77162.1 - 0.02 14.9 5.3 2 8.5 0.0 4.5 3 3 3 6 6 5 0 Tetratricopeptide repeat RRM_3 PF08777.6 KXX77162.1 - 0.037 13.8 1.1 0.12 12.1 0.0 2.4 2 1 1 3 3 3 0 RNA binding motif MIT PF04212.13 KXX77162.1 - 0.046 13.5 2.8 2.2 8.2 0.0 3.6 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 KXX77162.1 - 0.085 12.6 0.4 29 4.4 0.0 3.8 4 1 0 4 4 3 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.5 KXX77162.1 - 0.091 11.5 0.2 0.35 9.5 0.0 2.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Glyoxalase PF00903.20 KXX77162.1 - 0.11 12.4 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec63 PF02889.11 KXX77163.1 - 9e-45 153.2 0.0 9.9e-44 149.8 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KXX77163.1 - 6e-18 64.3 1.5 1.3e-17 63.3 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Afi1 PF07792.7 KXX77164.1 - 8.5e-62 207.4 0.0 1.6e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KXX77164.1 - 2.2e-37 127.2 0.0 4e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KXX77164.1 - 4.1e-08 32.1 0.3 0.021 13.3 0.0 3.4 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 KXX77164.1 - 0.025 13.8 0.0 0.21 10.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 KXX77165.1 - 6.4e-13 47.4 1.1 1.1e-05 24.8 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KXX77165.1 - 2.2e-10 39.0 1.4 0.00044 19.3 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KXX77165.1 - 9e-09 35.3 2.8 2.8e-07 30.5 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KXX77165.1 - 1.1e-06 27.6 4.7 0.00088 18.5 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KXX77165.1 - 3.9e-05 23.1 0.1 0.31 10.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KXX77165.1 - 0.0064 16.3 0.0 5.2 7.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain DUF2789 PF10982.3 KXX77165.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) Esterase PF00756.15 KXX77167.1 - 7.5e-48 163.1 0.0 8.9e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KXX77167.1 - 4.9e-08 32.8 0.0 6.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX77167.1 - 2.1e-05 24.5 0.1 2.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KXX77167.1 - 0.0001 21.6 0.1 0.00032 20.0 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX77167.1 - 0.0033 16.6 0.1 0.0063 15.7 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KXX77167.1 - 0.21 10.8 3.3 0.73 9.0 2.3 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family GARS_A PF01071.14 KXX77168.1 - 3.9e-82 274.5 0.0 5.5e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KXX77168.1 - 2.4e-35 120.9 0.0 7.2e-35 119.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KXX77168.1 - 1.7e-30 106.0 0.0 9.4e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KXX77168.1 - 3.6e-27 94.3 0.3 1.1e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KXX77168.1 - 8.2e-15 54.8 2.6 2.3e-14 53.3 1.1 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KXX77168.1 - 1.6e-11 44.3 0.0 3.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KXX77168.1 - 2.5e-08 33.0 0.0 1.2e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KXX77168.1 - 4.6e-06 26.1 0.0 8.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KXX77168.1 - 0.00014 21.2 0.2 0.00026 20.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KXX77168.1 - 0.0026 17.6 0.2 0.0063 16.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 KXX77168.1 - 0.022 14.1 0.2 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 KXX77168.1 - 0.022 14.2 0.4 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 KXX77168.1 - 0.073 12.4 0.2 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.1 KXX77168.1 - 0.15 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Ank PF00023.25 KXX77170.1 - 2.5e-81 263.6 1.1 1e-07 31.3 0.1 14.6 14 0 0 14 14 14 13 Ankyrin repeat Ank_2 PF12796.2 KXX77170.1 - 2.7e-80 264.7 10.1 3.2e-16 59.4 0.2 9.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX77170.1 - 6.2e-64 211.3 9.3 2e-10 40.8 0.0 12.0 5 2 9 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77170.1 - 3.2e-52 173.3 9.4 1.4e-08 34.6 0.1 11.3 3 1 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77170.1 - 9.7e-51 164.6 0.0 0.00014 21.7 0.0 15.6 15 0 0 15 15 15 10 Ankyrin repeat YscJ_FliF PF01514.12 KXX77170.1 - 0.031 13.4 0.3 0.12 11.5 0.0 2.0 2 1 1 3 3 3 0 Secretory protein of YscJ/FliF family Gal-3-0_sulfotr PF06990.6 KXX77170.1 - 0.37 9.3 1.0 0.65 8.5 0.7 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Pro_isomerase PF00160.16 KXX77171.1 - 1.1e-43 149.1 0.0 1.9e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KXX77171.1 - 6.4e-05 22.8 0.0 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.7 KXX77171.1 - 0.0009 18.5 0.0 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger MFS_1 PF07690.11 KXX77172.1 - 3.8e-39 134.4 61.4 3e-38 131.4 40.8 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77172.1 - 8.1e-10 37.8 15.0 8.1e-10 37.8 10.4 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 KXX77173.1 - 7.2e-07 28.8 0.4 0.00049 19.8 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat NACHT PF05729.7 KXX77173.1 - 4.4e-05 23.2 0.0 0.00018 21.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KXX77173.1 - 0.00014 21.7 0.0 0.00047 20.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX77173.1 - 0.00042 19.9 0.1 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KXX77173.1 - 0.0035 16.6 0.0 0.0082 15.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 KXX77173.1 - 0.018 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_5 PF12695.2 KXX77173.1 - 0.041 13.6 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3647 PF12363.3 KXX77173.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage protein Coatomer_WDAD PF04053.9 KXX77173.1 - 0.31 9.7 0.0 16 4.1 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region ArgK PF03308.11 KXX77173.1 - 0.31 9.7 0.0 0.61 8.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 KXX77173.1 - 0.44 9.4 0.0 0.69 8.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HET PF06985.6 KXX77175.1 - 7.1e-28 97.5 0.0 1.3e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hemerythrin PF01814.18 KXX77176.1 - 3.3e-13 49.9 0.1 4.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_Gp14 PF10666.4 KXX77176.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Phage protein Gp14 KTI12 PF08433.5 KXX77177.1 - 1.1e-62 211.6 0.0 2.1e-62 210.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KXX77177.1 - 6.8e-05 22.7 0.0 0.00022 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX77177.1 - 0.00092 20.0 0.0 0.003 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77177.1 - 0.0036 17.2 0.2 0.013 15.4 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain 6PF2K PF01591.13 KXX77177.1 - 0.0046 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_22 PF13401.1 KXX77177.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX77177.1 - 0.012 15.9 0.9 0.027 14.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KXX77177.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KXX77177.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase G-alpha PF00503.15 KXX77177.1 - 0.1 11.2 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Fungal_trans_2 PF11951.3 KXX77178.1 - 4.3e-11 42.0 0.5 9.4e-06 24.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77178.1 - 8.1e-08 32.0 10.9 2.1e-07 30.7 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.20 KXX77179.1 - 2.5e-47 161.5 0.0 2.9e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank PF00023.25 KXX77180.1 - 2.7e-32 108.9 2.7 1.8e-05 24.3 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KXX77180.1 - 9.9e-32 109.1 0.0 2.4e-18 66.2 0.1 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX77180.1 - 3e-27 94.4 1.6 7e-08 32.7 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77180.1 - 1.4e-19 68.1 0.4 0.042 14.1 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KXX77180.1 - 2.5e-15 56.1 3.3 0.007 16.5 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 KXX77180.1 - 4.9e-06 26.2 0.0 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX77180.1 - 0.025 14.5 0.0 0.13 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KXX77180.1 - 0.025 14.4 0.0 0.24 11.2 0.0 2.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KXX77180.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KXX77180.1 - 0.057 13.5 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KXX77181.1 - 3.2e-40 136.3 12.6 5.7e-15 55.4 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77181.1 - 2e-22 77.8 7.9 4.5e-05 23.0 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 KXX77181.1 - 3.3e-17 60.8 1.8 0.00077 19.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KXX77181.1 - 6.1e-15 55.2 1.6 7.8e-06 26.2 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77181.1 - 9.7e-13 47.9 2.3 0.00065 19.8 0.1 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DZR PF12773.2 KXX77181.1 - 0.014 15.2 3.2 0.032 14.0 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon RecR PF02132.10 KXX77181.1 - 0.069 12.5 1.6 0.42 10.0 1.1 2.3 1 1 0 1 1 1 0 RecR protein zinc_ribbon_2 PF13240.1 KXX77181.1 - 0.24 10.9 4.3 0.64 9.5 3.0 1.8 1 0 0 1 1 1 0 zinc-ribbon domain ZZ PF00569.12 KXX77181.1 - 1.6 8.3 6.9 3.2 7.3 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF1843 PF08898.5 KXX77181.1 - 2.5 8.1 6.6 11 6.1 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) C1_3 PF07649.7 KXX77181.1 - 5.8 7.0 11.5 0.074 13.0 2.5 1.8 2 0 0 2 2 2 0 C1-like domain Dehydratase_hem PF13816.1 KXX77182.1 - 9.4e-111 369.7 0.0 1.1e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 KXX77182.1 - 4.4e-06 26.7 0.1 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Peptidase_M41 PF01434.13 KXX77185.1 - 9.7e-67 224.5 0.6 1.7e-66 223.7 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KXX77185.1 - 7.5e-43 145.8 0.0 2e-42 144.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX77185.1 - 3e-05 24.1 0.5 0.0014 18.6 0.1 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 KXX77185.1 - 3.5e-05 23.5 0.2 0.00014 21.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KXX77185.1 - 3.8e-05 22.5 0.0 6.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KXX77185.1 - 8.5e-05 23.3 0.0 0.00021 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX77185.1 - 0.0002 21.5 0.1 0.0054 16.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX77185.1 - 0.00062 19.2 0.9 0.077 12.3 0.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX77185.1 - 0.00063 19.6 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX77185.1 - 0.0009 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX77185.1 - 0.0014 18.3 0.6 0.0064 16.2 0.4 2.1 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KXX77185.1 - 0.0032 16.9 0.2 0.0072 15.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KXX77185.1 - 0.0073 15.4 0.7 0.023 13.7 0.3 2.0 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KXX77185.1 - 0.016 14.4 0.2 0.044 12.9 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SpoU_sub_bind PF08032.7 KXX77185.1 - 0.018 15.2 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Bac_DnaA PF00308.13 KXX77185.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KXX77185.1 - 0.023 13.8 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 KXX77185.1 - 0.039 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KXX77185.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Beta_protein PF14350.1 KXX77185.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta protein AAA_2 PF07724.9 KXX77185.1 - 0.075 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KXX77185.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KXX77185.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KXX77185.1 - 0.12 11.5 0.4 0.32 10.1 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KXX77185.1 - 0.13 11.9 0.2 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Steroid_dh PF02544.11 KXX77186.1 - 1.1e-21 77.1 0.6 5e-21 75.0 0.4 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KXX77186.1 - 0.00029 20.2 0.3 0.00053 19.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2910 PF11139.3 KXX77186.1 - 0.0058 15.7 0.7 0.012 14.7 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2910) VGCC_beta4Aa_N PF12052.3 KXX77186.1 - 2.1 8.2 3.9 4.2 7.3 2.7 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF544 PF04424.8 KXX77188.1 - 5.2e-14 52.0 0.0 8.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF572 PF04502.8 KXX77188.1 - 1.9 7.5 8.3 4.5 6.3 5.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 KXX77188.1 - 8.3 4.5 10.4 14 3.8 7.2 1.2 1 0 0 1 1 1 0 Transmembrane protein ORC6 PF05460.8 KXX77189.1 - 1.5e-44 152.5 0.0 2.4e-44 151.8 0.0 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) RdRP_5 PF07925.6 KXX77189.1 - 0.23 8.7 0.0 0.31 8.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Epimerase PF01370.16 KXX77190.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX77190.1 - 6.2e-14 51.3 0.0 8.7e-14 50.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KXX77190.1 - 5.4e-12 46.0 0.3 1.2e-10 41.6 0.3 2.4 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KXX77190.1 - 6.5e-11 41.6 0.0 9.8e-11 41.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KXX77190.1 - 1e-06 28.7 0.1 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 KXX77190.1 - 9.4e-06 25.9 0.0 3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KXX77190.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 KXX77190.1 - 0.0041 17.1 0.2 0.029 14.4 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 KXX77190.1 - 0.0063 15.8 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Ala_racemase_N PF01168.15 KXX77190.1 - 0.069 12.6 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain Shikimate_DH PF01488.15 KXX77190.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PHO4 PF01384.15 KXX77191.1 - 1.3e-109 365.8 8.3 1.5e-109 365.5 5.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family Amnionless PF14828.1 KXX77191.1 - 0.28 9.6 0.0 0.44 8.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless HTH_IclR PF09339.5 KXX77191.1 - 0.59 9.7 2.9 7.2 6.2 0.1 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain QueT PF06177.6 KXX77192.1 - 0.046 13.6 4.9 0.085 12.8 3.4 1.5 1 1 0 1 1 1 0 QueT transporter EthD PF07110.6 KXX77193.1 - 6.6e-08 33.3 0.0 9.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 EthD domain CN_hydrolase PF00795.17 KXX77194.1 - 2.1e-27 95.6 0.1 2.8e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ufd2P_core PF10408.4 KXX77196.1 - 5.1e-206 685.7 5.3 6e-206 685.4 3.7 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KXX77196.1 - 9.2e-23 79.9 0.4 2.7e-22 78.5 0.3 1.9 1 0 0 1 1 1 1 U-box domain zf-TRAF PF02176.13 KXX77197.1 - 3e-14 53.1 28.2 2.8e-07 30.8 4.8 3.7 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 KXX77197.1 - 1.1e-09 37.8 3.7 1.1e-09 37.8 2.5 3.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX77197.1 - 2.1e-09 37.0 6.9 2.1e-09 37.0 4.8 3.5 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX77197.1 - 1.4e-08 34.6 6.9 1.4e-08 34.6 4.8 3.9 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX77197.1 - 4.6e-08 32.6 5.1 4.6e-08 32.6 3.6 3.4 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX77197.1 - 3.4e-07 29.8 7.2 3.4e-07 29.8 5.0 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX77197.1 - 5.3e-07 29.3 7.5 5.3e-07 29.3 5.2 2.7 4 0 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KXX77197.1 - 0.00064 19.7 2.1 0.00064 19.7 1.5 3.2 2 2 1 3 3 2 1 RING-H2 zinc finger U-box PF04564.10 KXX77197.1 - 0.0035 17.2 0.6 0.0088 15.9 0.1 1.9 2 0 0 2 2 1 1 U-box domain zf-RING_UBOX PF13445.1 KXX77197.1 - 0.82 9.4 19.9 0.039 13.6 8.4 2.8 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KXX77197.1 - 5.3 6.7 16.3 0.29 10.7 0.7 3.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain COesterase PF00135.23 KXX77198.1 - 2e-88 297.4 1.1 8e-79 265.7 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX77198.1 - 1.1e-13 51.2 0.2 1.8e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX77198.1 - 2.7e-08 33.9 0.6 5.1e-08 33.0 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX77198.1 - 5.9e-05 22.8 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_6 PF14259.1 KXX77199.1 - 3.7e-07 30.0 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 KXX77200.1 - 0.00025 21.0 7.4 0.00088 19.3 3.9 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4140 PF13600.1 KXX77200.1 - 0.14 12.5 0.5 0.14 12.5 0.4 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FTR1 PF03239.9 KXX77200.1 - 0.21 10.4 0.6 0.26 10.2 0.4 1.3 1 1 0 1 1 1 0 Iron permease FTR1 family Peptidase_S64 PF08192.6 KXX77200.1 - 0.23 9.7 1.1 0.29 9.4 0.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Pox_A12 PF04651.8 KXX77200.1 - 1.5 8.9 6.0 1.6 8.8 3.8 1.4 1 1 0 1 1 1 0 Poxvirus A12 protein DUF572 PF04502.8 KXX77200.1 - 6.9 5.7 9.3 4.9 6.2 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) His_Phos_1 PF00300.17 KXX77201.1 - 5.9e-31 107.6 0.0 7.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PMT PF02366.13 KXX77202.1 - 2.2e-73 246.6 17.3 4e-73 245.7 12.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KXX77202.1 - 6.3e-57 192.1 0.0 1e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 KXX77203.1 - 3.5e-59 200.1 20.3 2.4e-58 197.3 14.1 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KXX77203.1 - 5.2e-36 122.0 0.6 4.2e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 Surp module Cu-oxidase PF00394.17 KXX77203.1 - 0.094 12.6 0.0 0.51 10.2 0.0 2.2 1 1 0 1 1 1 0 Multicopper oxidase PX PF00787.19 KXX77204.1 - 2.2e-24 85.4 0.0 3.2e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 KXX77205.1 - 7e-78 256.4 1.8 7e-26 89.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EH_Signature PF15611.1 KXX77205.1 - 0.092 11.7 0.0 0.21 10.6 0.0 1.4 1 1 0 1 1 1 0 EH_Signature domain ARPC4 PF05856.7 KXX77206.1 - 1.2e-76 255.8 3.9 1.4e-76 255.6 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KXX77207.1 - 2.6e-56 190.6 0.0 3.3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX77207.1 - 1e-20 74.3 0.0 2.4e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KXX77207.1 - 1.1e-11 43.9 0.3 1.1e-11 43.9 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin family TPR_12 PF13424.1 KXX77208.1 - 1.1e-18 66.9 11.5 1.9e-07 30.8 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX77208.1 - 4.5e-17 61.8 0.0 7.9e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 KXX77208.1 - 1.7e-07 30.6 18.1 0.067 13.1 0.6 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77208.1 - 7.8e-07 28.6 11.2 0.096 12.3 1.3 4.7 2 1 4 6 6 6 5 TPR repeat TPR_14 PF13428.1 KXX77208.1 - 9.1e-07 28.9 18.7 0.18 12.5 0.1 6.6 7 1 1 8 8 6 3 Tetratricopeptide repeat AAA_16 PF13191.1 KXX77208.1 - 2.3e-06 27.7 2.6 5.7e-06 26.4 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.1 KXX77208.1 - 2.7e-05 24.6 20.3 0.031 14.9 0.9 5.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX77208.1 - 0.00093 19.2 3.2 3.8 7.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77208.1 - 0.0013 19.0 4.4 0.025 14.9 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KXX77208.1 - 0.0013 18.5 7.6 0.013 15.3 0.2 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KXX77208.1 - 0.0015 18.6 0.0 0.0052 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.1 KXX77208.1 - 0.0024 17.7 18.9 0.44 10.5 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX77208.1 - 0.0073 15.8 12.8 0.13 11.9 0.6 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KXX77208.1 - 0.015 15.6 9.4 6.1 7.5 0.2 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX77208.1 - 0.04 13.7 6.6 4.7 7.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Beta-lactamase PF00144.19 KXX77210.1 - 2e-42 145.4 0.2 2.6e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Pkinase PF00069.20 KXX77211.1 - 0.00014 21.1 0.0 0.00028 20.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77211.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.1 KXX77212.1 - 3.7e-10 39.1 0.0 7.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KXX77212.1 - 0.00035 20.5 0.0 0.00088 19.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain D5_N PF08706.6 KXX77212.1 - 0.16 12.0 0.7 0.3 11.1 0.5 1.5 1 0 0 1 1 1 0 D5 N terminal like NYD-SP28 PF14772.1 KXX77212.1 - 0.94 9.5 11.7 0.47 10.5 6.2 1.9 2 0 0 2 2 2 0 Sperm tail PV-1 PF06637.6 KXX77212.1 - 5 5.5 8.9 7.4 5.0 6.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) GAT PF03127.9 KXX77213.1 - 1.2e-18 66.9 0.7 2.4e-18 65.9 0.5 1.5 1 0 0 1 1 1 1 GAT domain DnaG_DnaB_bind PF08278.6 KXX77213.1 - 0.038 14.1 0.5 0.087 13.0 0.4 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding VHS PF00790.14 KXX77213.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 VHS domain Zn_clus PF00172.13 KXX77214.1 - 6e-08 32.4 7.7 9.3e-08 31.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KXX77215.1 - 9.7e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77215.1 - 4e-12 46.4 0.0 1.6e-11 44.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77215.1 - 4.6e-12 46.4 0.0 8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77215.1 - 3.2e-11 43.0 0.0 9.3e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77215.1 - 1.3e-09 38.2 0.1 5.9e-09 36.2 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77215.1 - 2e-08 34.6 0.0 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77215.1 - 2.8e-06 26.6 0.0 6.9e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX77215.1 - 3.1e-06 27.2 1.2 5.5e-06 26.4 0.4 1.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX77215.1 - 0.005 16.5 0.0 0.021 14.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 KXX77215.1 - 0.0074 15.6 0.0 0.015 14.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 KXX77215.1 - 0.022 13.8 0.0 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltrans_SAM PF10672.4 KXX77215.1 - 0.034 13.0 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase DREV PF05219.7 KXX77215.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 KXX77215.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Choline_kinase PF01633.15 KXX77216.1 - 0.00037 20.1 0.0 0.00067 19.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KXX77216.1 - 0.0056 15.8 0.0 0.019 14.1 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77216.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase ATP-synt_ab PF00006.20 KXX77217.1 - 7e-112 372.1 0.0 9.3e-112 371.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KXX77217.1 - 8.4e-16 58.4 0.2 1.5e-15 57.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KXX77217.1 - 1.4e-14 53.9 5.0 4e-14 52.5 2.7 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 KXX77217.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Securin PF04856.8 KXX77218.1 - 0.06 13.0 4.2 1.2 8.8 2.9 2.4 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Trm112p PF03966.11 KXX77219.1 - 1.2e-13 51.1 0.0 8.2e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 KXX77219.1 - 0.023 14.9 0.3 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ras PF00071.17 KXX77220.1 - 9.8e-32 109.5 0.3 1.2e-31 109.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX77220.1 - 4.5e-21 75.5 0.1 3.1e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX77220.1 - 3.6e-07 29.5 0.1 4.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX77220.1 - 2.1e-05 23.7 0.2 2.7e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 KXX77220.1 - 0.0057 15.3 0.2 0.25 9.9 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 KXX77220.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KXX77220.1 - 0.077 11.6 0.6 0.19 10.3 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit DUF4048 PF13257.1 KXX77221.1 - 1.8e-14 54.0 22.6 1.9e-13 50.6 7.4 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) N-SET PF11764.3 KXX77222.1 - 9e-44 149.3 0.1 9e-44 149.3 0.1 3.0 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KXX77222.1 - 5.7e-27 92.8 0.5 1.4e-26 91.5 0.4 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KXX77222.1 - 1e-24 87.6 0.2 1e-24 87.6 0.1 3.7 4 1 0 4 4 4 1 SET domain RRM_1 PF00076.17 KXX77222.1 - 0.093 12.3 0.2 8.7 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop25 PF09805.4 KXX77223.1 - 1.7e-35 122.0 11.4 1.7e-35 122.0 7.9 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.2 KXX77224.1 - 9.2e-50 168.2 34.0 1.1e-49 168.0 23.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KXX77224.1 - 5.4e-08 32.2 33.6 6.5e-05 22.1 13.1 2.9 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 KXX77224.1 - 2.2e-05 24.3 32.7 0.0021 17.8 3.2 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 KXX77224.1 - 0.00065 19.4 35.1 0.0017 18.1 10.7 3.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KXX77224.1 - 0.0011 18.7 19.4 0.012 15.3 2.2 2.1 1 1 1 2 2 2 2 Laminin Domain II Myosin_tail_1 PF01576.14 KXX77224.1 - 0.0023 15.7 31.3 0.0027 15.5 21.7 1.0 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KXX77224.1 - 0.003 17.4 27.5 0.14 11.9 7.1 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) LPP PF04728.8 KXX77224.1 - 0.0032 17.2 2.6 0.16 11.7 0.2 2.9 2 2 1 3 3 3 1 Lipoprotein leucine-zipper Cast PF10174.4 KXX77224.1 - 0.0053 14.8 27.8 0.0058 14.7 19.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Vps5 PF09325.5 KXX77224.1 - 0.0067 15.7 8.7 0.0067 15.7 6.0 2.8 2 1 1 3 3 3 1 Vps5 C terminal like NPV_P10 PF05531.7 KXX77224.1 - 0.012 15.8 10.5 0.21 11.8 2.4 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 KXX77224.1 - 0.015 14.3 33.4 0.29 10.1 11.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 KXX77224.1 - 0.018 14.7 26.9 0.082 12.6 11.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ERM PF00769.14 KXX77224.1 - 0.022 14.2 36.1 0.027 14.0 10.6 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 KXX77224.1 - 0.038 13.9 34.6 0.25 11.3 10.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HALZ PF02183.13 KXX77224.1 - 0.043 13.5 1.4 0.043 13.5 1.0 4.8 4 3 0 4 4 4 0 Homeobox associated leucine zipper EzrA PF06160.7 KXX77224.1 - 0.046 11.8 23.3 0.1 10.7 3.7 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA PilJ PF13675.1 KXX77224.1 - 0.047 13.9 12.4 0.78 10.0 2.7 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.3 KXX77224.1 - 0.05 13.4 29.6 0.33 10.8 6.4 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 KXX77224.1 - 0.056 13.4 28.7 0.49 10.4 7.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 KXX77224.1 - 0.061 12.5 31.0 0.23 10.6 11.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.7 KXX77224.1 - 0.067 13.1 11.7 1.1 9.1 0.3 2.9 2 2 1 3 3 3 0 MbeD/MobD like BRE1 PF08647.6 KXX77224.1 - 0.073 13.0 27.7 0.26 11.2 2.9 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.4 KXX77224.1 - 0.077 12.9 25.5 0.089 12.7 11.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Reo_sigmaC PF04582.7 KXX77224.1 - 0.089 11.9 3.5 2.5 7.1 0.3 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 KXX77224.1 - 0.094 12.7 28.1 1.2 9.2 0.4 3.7 1 1 3 4 4 4 0 Cortexillin I, coiled coil bZIP_1 PF00170.16 KXX77224.1 - 0.095 12.6 30.6 0.25 11.2 0.9 4.9 1 1 4 5 5 5 0 bZIP transcription factor KLRAQ PF10205.4 KXX77224.1 - 0.099 12.6 20.0 0.049 13.6 5.3 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TBPIP PF07106.8 KXX77224.1 - 0.11 12.0 27.0 0.52 9.8 6.3 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KXX77224.1 - 0.13 12.1 15.4 0.19 11.5 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KXX77224.1 - 0.13 12.4 21.8 1.5 9.0 5.6 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 KXX77224.1 - 0.13 12.1 25.1 1.4 8.7 12.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.16 KXX77224.1 - 0.13 11.6 26.4 1.1 8.6 7.0 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 KXX77224.1 - 0.14 12.5 22.6 0.14 12.4 7.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KXX77224.1 - 0.15 11.6 31.8 5.4 6.5 22.0 2.3 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 KXX77224.1 - 0.2 10.5 26.2 0.082 11.8 11.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HalX PF08663.5 KXX77224.1 - 0.22 11.5 17.7 0.44 10.5 0.0 4.3 2 2 2 4 4 4 0 HalX domain CCDC155 PF14662.1 KXX77224.1 - 0.22 11.0 32.7 1.2 8.7 9.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Syntaxin-6_N PF09177.6 KXX77224.1 - 0.23 11.9 17.6 3.1 8.2 3.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 KXX77224.1 - 0.27 9.8 27.3 0.026 13.1 10.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KXX77224.1 - 0.29 11.2 17.4 0.54 10.3 3.0 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 KXX77224.1 - 0.31 10.4 24.1 6.9 6.0 16.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) IFT46_B_C PF12317.3 KXX77224.1 - 0.46 9.8 7.4 0.26 10.6 3.4 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Laminin_I PF06008.9 KXX77224.1 - 0.52 9.5 24.1 0.096 11.9 5.1 2.4 1 1 1 2 2 2 0 Laminin Domain I Striatin PF08232.7 KXX77224.1 - 0.63 10.3 23.4 0.5 10.6 9.7 2.2 1 1 1 2 2 2 0 Striatin family DUF869 PF05911.6 KXX77224.1 - 0.67 8.1 25.4 0.99 7.5 6.6 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Fmp27_WPPW PF10359.4 KXX77224.1 - 0.72 8.2 22.0 0.14 10.5 5.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.10 KXX77224.1 - 0.74 9.3 33.9 2.7 7.5 8.7 4.3 1 1 3 4 4 4 0 Septum formation initiator FUSC PF04632.7 KXX77224.1 - 0.87 7.9 6.8 1.1 7.6 4.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nsp1_C PF05064.8 KXX77224.1 - 0.89 9.2 20.2 0.052 13.1 3.9 2.7 1 1 0 2 2 2 0 Nsp1-like C-terminal region AAA_13 PF13166.1 KXX77224.1 - 0.91 7.9 23.4 1.6 7.0 16.2 1.4 1 1 0 1 1 1 0 AAA domain DUF342 PF03961.8 KXX77224.1 - 0.97 7.7 25.9 0.64 8.3 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3287 PF11690.3 KXX77224.1 - 1.2 9.2 9.7 0.18 11.8 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) FlaC_arch PF05377.6 KXX77224.1 - 1.4 8.8 16.4 11 5.9 0.1 4.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KXX77224.1 - 1.5 9.2 24.1 0.3 11.5 2.2 3.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 KXX77224.1 - 1.6 6.4 18.3 2.2 6.0 12.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KXX77224.1 - 1.9 5.7 26.2 2.7 5.2 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CDC37_N PF03234.9 KXX77224.1 - 2.2 8.5 22.6 10 6.4 15.7 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3166 PF11365.3 KXX77224.1 - 2.2 8.7 18.4 14 6.2 8.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3166) DUF812 PF05667.6 KXX77224.1 - 3.5 6.0 26.4 45 2.3 18.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 KXX77224.1 - 3.9 7.0 30.0 8.2 6.0 7.5 2.2 1 1 1 2 2 2 0 Mnd1 family Nup54 PF13874.1 KXX77224.1 - 4.5 6.9 24.0 2.9 7.5 5.6 2.9 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF724 PF05266.9 KXX77224.1 - 5.1 6.6 28.1 1.2 8.6 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.8 KXX77224.1 - 5.7 6.8 26.1 36 4.2 11.2 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EHN PF06441.7 KXX77224.1 - 5.8 6.8 12.8 2.5 8.0 3.0 2.8 1 1 2 3 3 3 0 Epoxide hydrolase N terminus Syntaxin PF00804.20 KXX77224.1 - 6.4 6.9 21.5 4.8 7.4 6.9 2.5 1 1 1 2 2 2 0 Syntaxin Phage_GP20 PF06810.6 KXX77224.1 - 6.5 6.1 28.1 11 5.4 6.8 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 bZIP_2 PF07716.10 KXX77224.1 - 7.7 6.4 35.6 0.2 11.4 0.5 5.3 2 1 5 7 7 6 0 Basic region leucine zipper TPR_MLP1_2 PF07926.7 KXX77224.1 - 8 6.2 33.8 7.7 6.2 10.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 KXX77224.1 - 8.8 5.5 25.1 4 6.6 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MAD PF05557.8 KXX77224.1 - 9.7 4.1 29.1 2.4 6.1 9.3 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF4559 PF15112.1 KXX77224.1 - 9.8 5.2 16.0 17 4.4 11.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Apc13p PF05839.6 KXX77225.1 - 5.3e-35 119.2 0.0 6.8e-35 118.9 0.0 1.1 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 KXX77226.1 - 4e-35 120.5 0.0 4.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Pro_isomerase PF00160.16 KXX77227.1 - 4.7e-47 160.0 0.9 5.5e-47 159.8 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1942 PF09167.6 KXX77227.1 - 0.087 12.5 0.1 0.27 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1942) Syntaxin-6_N PF09177.6 KXX77228.1 - 9.9e-26 89.9 0.4 4.3e-25 87.9 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KXX77228.1 - 3.1e-14 52.3 9.4 5.4e-14 51.6 3.1 3.0 3 0 0 3 3 3 1 SNARE domain PilJ PF13675.1 KXX77228.1 - 0.035 14.4 3.2 0.16 12.2 0.3 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Gag_spuma PF03276.9 KXX77228.1 - 0.1 10.9 0.4 0.14 10.4 0.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Filament PF00038.16 KXX77228.1 - 0.17 11.2 3.9 0.31 10.4 0.3 2.2 2 1 0 2 2 2 0 Intermediate filament protein DUF1470 PF07336.6 KXX77228.1 - 0.33 11.2 5.6 2.6 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DUF4164 PF13747.1 KXX77228.1 - 2.4 8.3 7.9 0.69 10.0 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Ferritin_2 PF13668.1 KXX77229.1 - 4.8e-40 136.6 0.7 8.4e-40 135.8 0.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain CitT PF12431.3 KXX77229.1 - 0.022 14.8 0.1 0.63 10.1 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator ELFV_dehydrog PF00208.16 KXX77230.1 - 9.7e-79 264.3 2.0 1.2e-78 264.0 1.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KXX77230.1 - 1.6e-47 160.3 0.0 5.2e-47 158.7 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KXX77230.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding GLE1 PF07817.8 KXX77231.1 - 4.3e-23 81.5 0.0 3.6e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.3 KXX77231.1 - 7 5.9 15.2 0.63 9.3 7.0 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNB PF00773.14 KXX77232.1 - 2.8e-74 250.3 0.0 8.3e-74 248.7 0.0 1.8 2 0 0 2 2 2 1 RNB domain DUF4239 PF14023.1 KXX77232.1 - 0.026 13.8 0.2 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ATP-synt_S1 PF05827.7 KXX77233.1 - 1e-44 152.9 0.0 1.4e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) TIP120 PF08623.5 KXX77234.1 - 9.1e-70 233.6 3.9 1.8e-65 219.6 0.0 4.5 3 1 2 5 5 5 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KXX77234.1 - 1.3e-20 73.4 22.6 0.00075 19.7 0.1 9.8 7 2 3 11 11 11 6 HEAT repeats HEAT PF02985.17 KXX77234.1 - 2e-15 55.4 21.0 0.051 13.6 0.0 11.3 11 0 0 11 11 10 4 HEAT repeat Cnd1 PF12717.2 KXX77234.1 - 1.4e-07 31.5 6.9 1.1 9.1 0.0 6.6 5 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KXX77234.1 - 6.9e-07 27.9 13.1 0.0045 15.3 0.1 6.9 7 1 1 8 8 8 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KXX77234.1 - 1.1e-06 28.9 1.3 0.3 11.5 0.0 7.4 6 4 2 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KXX77234.1 - 2.8e-06 27.6 32.1 0.13 12.8 0.5 13.3 11 5 7 18 18 17 2 HEAT-like repeat VHS PF00790.14 KXX77234.1 - 0.00015 21.3 0.0 0.32 10.6 0.0 3.0 2 0 0 2 2 2 2 VHS domain Proteasom_PSMB PF10508.4 KXX77234.1 - 0.0018 16.6 0.2 0.76 7.9 0.1 2.7 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 KXX77234.1 - 0.0025 17.2 2.4 0.24 10.7 0.0 4.3 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 KXX77234.1 - 0.0093 15.7 6.7 9.3 6.2 0.0 6.4 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.3 KXX77234.1 - 0.13 11.9 1.5 59 3.4 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) RasGEF_N_2 PF14663.1 KXX77234.1 - 0.15 12.0 0.3 36 4.3 0.0 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain API5 PF05918.6 KXX77234.1 - 1.5 7.1 4.9 10 4.4 0.0 3.4 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Ycf1 PF05758.7 KXX77235.1 - 0.0031 15.3 4.3 0.0038 15.0 3.0 1.0 1 0 0 1 1 1 1 Ycf1 Vfa1 PF08432.5 KXX77235.1 - 4.3 7.3 19.6 5.7 6.9 13.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 KXX77235.1 - 6 6.3 20.7 6.6 6.1 14.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Porphobil_deam PF01379.15 KXX77236.1 - 4e-75 251.4 0.0 5.3e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KXX77236.1 - 2.4e-18 66.0 1.3 4.7e-18 65.0 0.9 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.14 KXX77237.1 - 6.7e-33 112.9 0.6 8.1e-33 112.6 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein BRCT PF00533.21 KXX77240.1 - 3.4e-05 23.9 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RR_TM4-6 PF06459.7 KXX77240.1 - 8.8 6.1 10.9 1.6 8.5 0.9 2.6 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 CoA_binding_2 PF13380.1 KXX77241.1 - 2.3e-26 92.2 0.0 2.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain GTP1_OBG PF01018.17 KXX77241.1 - 0.081 12.5 0.2 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 GTP1/OBG DUF3716 PF12511.3 KXX77242.1 - 2e-16 59.3 7.7 3.2e-13 49.0 2.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) NOA36 PF06524.7 KXX77242.1 - 0.037 13.2 14.4 0.073 12.3 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-C_C PF11699.3 KXX77242.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Daxx PF03344.10 KXX77242.1 - 0.12 10.8 8.3 0.23 9.8 5.8 1.4 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 KXX77242.1 - 0.32 10.5 8.1 0.6 9.6 5.6 1.3 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 KXX77242.1 - 3.2 8.1 21.3 36 4.7 12.5 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SH3_1 PF00018.23 KXX77243.1 - 3.7e-27 93.4 0.0 1.4e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KXX77243.1 - 8.2e-19 66.9 0.1 7.2e-09 35.0 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KXX77243.1 - 7.5e-15 54.7 0.0 1.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KXX77243.1 - 9.1e-14 50.6 0.0 1.7e-08 33.8 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 KXX77243.1 - 2.4e-09 36.6 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.11 KXX77244.1 - 4.3e-68 228.9 1.4 5.6e-68 228.5 1.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KXX77244.1 - 0.00046 19.9 0.1 0.0011 18.7 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HTH_Tnp_Tc5 PF03221.11 KXX77246.1 - 1.4e-16 60.0 1.9 1e-15 57.2 0.2 2.9 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 KXX77246.1 - 0.0012 19.6 2.5 1 10.2 0.0 3.4 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.1 KXX77246.1 - 0.0054 16.8 2.2 0.12 12.5 0.2 2.9 2 1 0 2 2 2 1 Winged helix-turn helix DUF4604 PF15377.1 KXX77246.1 - 0.13 12.5 0.2 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2611 PF11022.3 KXX77247.1 - 4.5e-30 103.5 0.2 5.3e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 KXX77248.1 - 1.8e-67 225.8 0.0 2.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) EAP30 PF04157.11 KXX77249.1 - 2.5e-57 193.5 0.0 3.2e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KXX77249.1 - 1.1e-27 95.6 0.0 1.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KXX77249.1 - 0.00042 19.7 0.0 0.00075 18.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 KXX77249.1 - 0.0024 17.3 5.4 0.011 15.3 0.3 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 KXX77249.1 - 0.11 11.6 14.7 0.027 13.5 0.8 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.2 KXX77249.1 - 1.3 8.9 6.0 0.18 11.6 0.2 2.2 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_M3 PF01432.15 KXX77251.1 - 4.8e-159 530.2 0.0 6e-159 529.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 KXX77251.1 - 0.0053 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Effector protein TPR_12 PF13424.1 KXX77252.1 - 5.5e-14 51.8 8.1 6.8e-08 32.3 1.2 5.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KXX77252.1 - 1.5e-06 27.9 7.8 0.14 12.1 0.3 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX77252.1 - 2e-06 27.1 1.3 2.7 7.7 0.1 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77252.1 - 3.8e-06 27.1 0.0 0.0039 17.5 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77252.1 - 2.7e-05 23.7 6.7 0.057 13.0 0.3 4.9 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.1 KXX77252.1 - 0.0004 20.7 3.2 0.93 10.3 0.3 5.3 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77252.1 - 0.00054 19.6 7.0 0.27 11.2 0.7 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 KXX77252.1 - 0.018 14.8 0.3 6.8 6.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 KXX77252.1 - 0.033 13.6 0.5 0.092 12.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) IRF PF00605.12 KXX77252.1 - 0.081 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor NB-ARC PF00931.17 KXX77252.1 - 0.14 11.0 0.0 11 4.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.17 KXX77252.1 - 0.25 10.7 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_16 PF13432.1 KXX77252.1 - 5.4 7.8 9.8 0.41 11.3 0.3 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat CorA PF01544.13 KXX77254.1 - 0.064 12.2 0.5 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.1 KXX77255.1 - 7.9e-67 225.6 38.0 1.1e-66 225.1 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX77255.1 - 2.4e-09 36.0 33.0 4.2e-09 35.2 22.9 1.4 1 1 0 1 1 1 1 Amino acid permease EF-hand_7 PF13499.1 KXX77257.1 - 4.7e-15 55.4 0.1 2.5e-10 40.3 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KXX77257.1 - 9.5e-12 43.7 0.3 0.00078 19.1 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KXX77257.1 - 1e-10 41.3 0.0 0.0001 22.1 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KXX77257.1 - 2.8e-10 38.7 0.2 0.012 14.8 0.0 4.1 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KXX77257.1 - 1.1e-08 34.5 0.5 0.00034 20.1 0.0 3.4 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KXX77257.1 - 0.029 13.7 1.2 2.2 7.7 0.7 3.2 3 0 0 3 3 3 0 EF hand Amidase PF01425.16 KXX77258.1 - 1.2e-39 136.3 0.0 1.8e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Rad4 PF03835.10 KXX77259.1 - 2.4e-33 114.5 0.3 9.4e-33 112.6 0.2 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KXX77259.1 - 8e-27 92.7 0.1 1.5e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KXX77259.1 - 4.1e-20 71.0 0.1 8.4e-20 70.0 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KXX77259.1 - 1.4e-16 60.5 0.2 1.4e-16 60.5 0.1 4.1 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KXX77259.1 - 0.0006 20.0 0.1 0.0032 17.6 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily zf-AN1 PF01428.11 KXX77260.1 - 2.1e-25 88.3 20.1 1.4e-13 50.4 4.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KXX77260.1 - 0.0011 18.7 14.0 0.13 12.1 2.5 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 KXX77260.1 - 0.022 14.9 13.6 0.061 13.5 3.2 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-H2C2_2 PF13465.1 KXX77260.1 - 3.3 8.1 7.1 6 7.3 1.6 2.9 2 1 0 2 2 2 0 Zinc-finger double domain DUF2036 PF09724.4 KXX77261.1 - 2.8e-07 29.9 0.0 3.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 KXX77262.1 - 2e-05 24.3 42.3 0.00037 20.3 3.4 4.9 4 1 0 4 4 4 2 IBR domain DUF4217 PF13959.1 KXX77262.1 - 0.11 12.0 0.0 0.54 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) PI31_Prot_N PF11566.3 KXX77263.1 - 4e-36 123.9 0.0 4.7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KXX77263.1 - 1.4e-16 60.8 24.1 1.4e-16 60.8 16.7 4.2 3 1 1 4 4 4 1 PI31 proteasome regulator YppG PF14179.1 KXX77263.1 - 6.6 7.3 10.9 10 6.7 7.5 1.3 1 0 0 1 1 1 0 YppG-like protein A_deaminase PF00962.17 KXX77264.1 - 2.2e-46 158.3 0.7 1.5e-42 145.7 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KXX77264.1 - 0.0041 17.1 2.6 0.03 14.3 1.8 2.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal DUF3437 PF11919.3 KXX77264.1 - 6.6 6.5 6.1 9.9 5.9 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF4131 PF13567.1 KXX77265.1 - 0.15 11.4 2.4 5.6 6.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1469 PF07332.6 KXX77265.1 - 0.77 9.5 6.0 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2207 PF09972.4 KXX77265.1 - 6.3 5.2 5.2 11 4.4 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PEX11 PF05648.9 KXX77266.1 - 2.8e-16 59.4 0.0 3.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SRP40_C PF05022.7 KXX77267.1 - 1.5e-24 86.2 0.8 4.6e-24 84.6 0.5 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 KXX77267.1 - 0.0049 15.1 52.3 0.0071 14.5 36.2 1.2 1 0 0 1 1 1 1 Utp14 protein ABC_tran PF00005.22 KXX77268.1 - 6.5e-50 168.9 0.9 2.3e-23 83.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KXX77268.1 - 9.7e-21 73.4 6.9 9.7e-21 73.4 4.8 4.2 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.1 KXX77268.1 - 1.3e-17 64.6 0.0 0.00018 21.5 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KXX77268.1 - 3e-10 39.7 5.8 0.0043 16.3 0.0 4.6 5 0 0 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KXX77268.1 - 2e-09 38.3 0.5 0.0018 19.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 KXX77268.1 - 3.2e-07 29.7 3.8 0.77 8.7 0.0 4.5 4 2 0 4 4 4 3 AAA ATPase domain Miro PF08477.8 KXX77268.1 - 3.8e-07 30.6 0.4 0.0067 16.9 0.0 3.4 3 0 0 3 3 3 2 Miro-like protein AAA_18 PF13238.1 KXX77268.1 - 4.5e-07 30.2 0.2 0.04 14.2 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 KXX77268.1 - 7.1e-07 28.6 0.1 0.0092 15.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KXX77268.1 - 7.4e-07 29.1 0.0 0.011 15.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KXX77268.1 - 1.6e-06 27.3 0.1 0.011 14.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX77268.1 - 4.8e-06 26.6 2.4 0.0026 17.7 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KXX77268.1 - 5.5e-06 26.3 0.0 0.092 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX77268.1 - 6.5e-06 26.3 0.0 0.12 12.5 0.0 3.1 2 2 0 2 2 2 2 AAA domain MobB PF03205.9 KXX77268.1 - 1.9e-05 24.3 0.2 0.18 11.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KXX77268.1 - 0.00021 21.5 0.0 0.41 10.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KXX77268.1 - 0.00041 20.3 4.9 0.034 14.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KXX77268.1 - 0.00085 19.6 0.0 0.038 14.3 0.0 4.7 4 1 1 5 5 5 2 AAA domain AAA_14 PF13173.1 KXX77268.1 - 0.00086 19.2 0.0 1.6 8.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 KXX77268.1 - 0.00093 18.8 0.2 1.4 8.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain ATP-synt_ab PF00006.20 KXX77268.1 - 0.0016 17.9 0.1 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 KXX77268.1 - 0.0017 18.2 0.2 2.1 8.2 0.1 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 KXX77268.1 - 0.0036 17.0 0.1 0.71 9.5 0.1 2.8 2 0 0 2 2 2 1 NTPase cobW PF02492.14 KXX77268.1 - 0.0049 16.3 0.4 1.5 8.2 0.3 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KXX77268.1 - 0.0052 16.9 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KXX77268.1 - 0.0098 14.6 7.6 0.29 9.8 0.1 3.1 4 0 0 4 4 4 2 ArgK protein T2SE PF00437.15 KXX77268.1 - 0.015 14.1 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KXX77268.1 - 0.016 15.0 12.1 0.24 11.2 0.0 4.2 3 1 0 4 4 4 0 Dynamin family AAA_25 PF13481.1 KXX77268.1 - 0.017 14.4 0.0 7.6 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KXX77268.1 - 0.022 14.4 0.3 5.4 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KXX77268.1 - 0.024 14.0 2.2 4.2 6.7 0.0 3.8 5 0 0 5 5 4 0 AAA-like domain NB-ARC PF00931.17 KXX77268.1 - 0.026 13.3 0.0 5.9 5.6 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain Halo_GVPC PF05465.8 KXX77268.1 - 0.038 13.9 0.7 0.14 12.1 0.2 2.2 2 0 0 2 2 1 0 Halobacterial gas vesicle protein C (GVPC) repeat GTP_EFTU PF00009.22 KXX77268.1 - 0.065 12.6 2.4 7.1 6.0 0.0 3.0 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 KXX77268.1 - 0.076 12.7 0.6 4.9 6.9 0.1 3.3 3 0 0 3 3 3 0 Part of AAA domain PduV-EutP PF10662.4 KXX77268.1 - 0.099 12.1 0.1 16 4.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KXX77268.1 - 0.14 11.7 0.9 24 4.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Tubulin PF00091.20 KXX77269.1 - 2.7e-70 236.5 0.0 4.6e-70 235.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KXX77269.1 - 9.9e-49 164.5 0.2 1.5e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KXX77269.1 - 8.9e-06 25.7 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KXX77269.1 - 0.0029 17.1 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bZIP_1 PF00170.16 KXX77270.1 - 1.1e-12 47.7 4.8 1.8e-12 47.0 3.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX77270.1 - 2.6e-05 23.9 10.0 4.8e-05 23.0 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KXX77270.1 - 0.066 12.1 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.12 KXX77270.1 - 0.085 13.1 3.9 0.18 12.1 2.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 KXX77272.1 - 1.3e-05 25.0 5.9 2e-05 24.4 4.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX77272.1 - 0.0033 17.2 7.7 0.005 16.6 5.3 1.2 1 0 0 1 1 1 1 Basic region leucine zipper YopE_N PF09020.5 KXX77272.1 - 0.015 15.3 0.2 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 YopE, N terminal TPR_MLP1_2 PF07926.7 KXX77273.1 - 9.1e-31 106.3 28.7 9.1e-31 106.3 19.9 17.7 6 5 10 16 16 16 7 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 KXX77273.1 - 0.0034 17.3 6.8 0.0034 17.3 4.7 21.2 7 4 9 19 19 19 4 Domain of unknown function (DUF4200) Striatin PF08232.7 KXX77273.1 - 0.0062 16.8 6.7 0.0062 16.8 4.7 16.9 5 4 11 16 16 16 4 Striatin family Complex1_51K PF01512.12 KXX77274.1 - 7.8e-47 158.7 0.0 1.3e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KXX77274.1 - 1.8e-17 62.2 1.1 1.8e-17 62.2 0.8 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KXX77274.1 - 1.9e-09 37.2 0.0 4.5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Flavoprotein PF02441.14 KXX77275.1 - 3.4e-18 65.5 0.1 5.7e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein Hexapep PF00132.19 KXX77276.1 - 1.9e-07 30.2 2.7 2.1e-06 26.9 1.8 2.4 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KXX77276.1 - 0.045 13.3 1.4 0.19 11.2 0.7 2.1 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Podoplanin PF05808.6 KXX77277.1 - 0.013 15.0 1.1 0.024 14.2 0.8 1.4 1 1 0 1 1 1 0 Podoplanin CD99L2 PF12301.3 KXX77277.1 - 0.019 14.6 0.5 0.052 13.2 0.3 1.7 1 0 0 1 1 1 0 CD99 antigen like protein 2 Syndecan PF01034.15 KXX77277.1 - 0.021 14.4 1.1 0.041 13.5 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain Sec34 PF04136.10 KXX77278.1 - 9.4e-29 100.1 0.1 1.8e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.13 KXX77279.1 - 1.5e-28 98.7 6.6 1.2e-06 28.5 0.0 7.3 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KXX77279.1 - 3.4e-15 55.1 18.8 1e-09 37.7 0.0 7.4 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat MobB PF03205.9 KXX77280.1 - 0.0044 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KXX77280.1 - 0.0088 15.9 0.1 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX77280.1 - 0.01 16.6 0.0 0.021 15.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX77280.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Bromodomain PF00439.20 KXX77281.1 - 7.3e-19 67.4 0.2 7.3e-19 67.4 0.1 2.0 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KXX77281.1 - 4.1e-11 42.4 0.1 1.1e-10 41.0 0.1 1.9 1 1 0 1 1 1 1 Bromodomain associated SHMT PF00464.14 KXX77282.1 - 5.1e-212 703.4 0.0 6e-212 703.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KXX77282.1 - 0.00017 20.4 0.0 0.00025 19.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KXX77282.1 - 0.00045 19.2 0.0 0.0013 17.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KXX77282.1 - 0.0068 15.5 0.0 0.013 14.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase KKLCAg1 PF15204.1 KXX77282.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Peptidase_A3 PF02160.10 KXX77282.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) DUF155 PF02582.9 KXX77284.1 - 9.8e-44 149.3 0.0 1.5e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 KXX77284.1 - 0.088 12.2 0.3 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) RINT1_TIP1 PF04437.8 KXX77285.1 - 3.2e-100 336.0 0.0 5.2e-100 335.3 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ADIP PF11559.3 KXX77285.1 - 0.0063 16.4 1.5 0.026 14.4 1.0 2.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding COG2 PF06148.6 KXX77285.1 - 1.3 8.8 5.6 0.26 11.1 0.3 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mito_carr PF00153.22 KXX77286.1 - 1.9e-61 203.7 2.0 7.2e-22 76.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.15 KXX77287.1 - 9.7e-14 51.1 1.2 1.4e-13 50.6 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain MCM_bind PF09739.4 KXX77287.1 - 0.016 14.7 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA PF00004.24 KXX77289.1 - 1.6e-45 154.5 0.2 6.1e-45 152.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX77289.1 - 6.6e-09 35.6 0.4 2.9e-08 33.5 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX77289.1 - 4.8e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KXX77289.1 - 3.8e-07 30.2 0.0 1.4e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX77289.1 - 1.1e-06 28.7 1.4 0.001 19.1 0.0 2.9 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 KXX77289.1 - 2.9e-06 26.3 0.0 6.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KXX77289.1 - 0.00017 21.4 0.1 0.00083 19.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 KXX77289.1 - 0.00036 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KXX77289.1 - 0.00039 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX77289.1 - 0.00046 20.9 0.0 0.0023 18.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KXX77289.1 - 0.00065 19.4 0.9 0.057 13.0 0.0 3.1 2 1 0 3 3 3 1 NACHT domain TIP49 PF06068.8 KXX77289.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KXX77289.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KXX77289.1 - 0.0014 17.8 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KXX77289.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 KXX77289.1 - 0.0025 17.5 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 KXX77289.1 - 0.0036 16.8 0.0 0.011 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KXX77289.1 - 0.0044 17.3 0.4 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KXX77289.1 - 0.0045 16.6 0.6 0.018 14.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KXX77289.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KXX77289.1 - 0.0052 16.4 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KXX77289.1 - 0.006 15.7 0.2 0.013 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KXX77289.1 - 0.0083 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KXX77289.1 - 0.0085 15.8 0.6 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 KXX77289.1 - 0.0086 15.6 0.5 0.03 13.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KXX77289.1 - 0.0088 15.4 0.6 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KXX77289.1 - 0.0092 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Clathrin_H_link PF13838.1 KXX77289.1 - 0.013 15.3 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 Clathrin-H-link Bac_DnaA PF00308.13 KXX77289.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Cast PF10174.4 KXX77289.1 - 0.022 12.8 2.5 0.038 12.0 1.1 1.6 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Viral_Hsp90 PF03225.9 KXX77289.1 - 0.029 12.6 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue KaiC PF06745.8 KXX77289.1 - 0.033 13.3 1.3 0.45 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 KXX77289.1 - 0.04 13.4 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 KXX77289.1 - 0.051 12.3 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 KXX77289.1 - 0.053 13.5 0.1 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KXX77289.1 - 0.054 12.8 4.8 0.07 12.5 0.1 2.8 3 1 1 4 4 3 0 AAA domain NB-ARC PF00931.17 KXX77289.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KXX77289.1 - 0.16 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CRAL_TRIO PF00650.15 KXX77290.1 - 1.3e-35 122.2 0.0 2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX77290.1 - 3.5e-09 36.6 1.7 5.8e-09 35.9 0.2 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KXX77290.1 - 9.8e-05 22.2 0.0 0.00077 19.3 0.0 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 KXX77291.1 - 3.5e-05 23.8 1.4 3.5e-05 23.8 1.0 1.8 2 1 0 2 2 2 1 Kinetochore protein Mis14 like DUF4407 PF14362.1 KXX77291.1 - 1.7 7.5 6.7 2.7 6.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.7 KXX77291.1 - 2.3 8.2 7.9 7.5 6.6 0.1 3.5 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat VanZ PF04892.7 KXX77292.1 - 2e-13 50.4 2.9 2.7e-13 50.0 2.0 1.1 1 0 0 1 1 1 1 VanZ like family Asp-Al_Ex PF06826.7 KXX77292.1 - 0.009 15.5 0.3 0.015 14.8 0.1 1.3 1 1 0 1 1 1 1 Predicted Permease Membrane Region ABC_membrane_3 PF13748.1 KXX77292.1 - 0.061 12.3 1.5 0.081 11.9 1.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region NAD_binding_6 PF08030.7 KXX77293.1 - 1e-17 64.4 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KXX77293.1 - 4.1e-17 62.4 8.5 4.1e-17 62.4 5.9 1.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KXX77293.1 - 1.1e-06 29.1 0.2 0.034 14.7 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 KXX77293.1 - 4.9e-06 26.3 0.0 3e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain Y_phosphatase PF00102.22 KXX77294.1 - 2.7e-47 161.1 0.0 3.9e-38 131.1 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KXX77294.1 - 0.00082 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KXX77294.1 - 0.0023 17.5 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KXX77294.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Folliculin PF11704.3 KXX77295.1 - 6.4e-29 100.7 0.0 1.5e-28 99.4 0.0 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Ribonuc_L-PSP PF01042.16 KXX77296.1 - 6.2e-40 135.7 0.0 6.9e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP LETM1 PF07766.8 KXX77297.1 - 2.7e-08 33.1 0.1 4.6e-07 29.1 0.0 2.0 1 1 1 2 2 2 2 LETM1-like protein RRM_1 PF00076.17 KXX77298.1 - 9e-10 38.0 0.0 1.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77298.1 - 5.2e-06 26.3 0.0 8.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77298.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.1 KXX77299.1 - 2.3e-81 271.8 0.0 3.6e-81 271.1 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KXX77299.1 - 4.6e-65 218.5 0.0 1.5e-64 216.8 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KXX77299.1 - 2.7e-40 135.9 0.0 6.3e-40 134.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KXX77299.1 - 8e-36 122.1 0.8 2.3e-35 120.7 0.6 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 KXX77299.1 - 0.0016 18.5 0.2 0.27 11.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain Acetyltransf_7 PF13508.1 KXX77299.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KXX77300.1 - 2.3e-69 233.4 0.0 2.8e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77300.1 - 1.5e-29 102.9 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX77300.1 - 2.2e-06 26.8 0.0 3.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX77300.1 - 0.00031 20.5 0.1 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX77300.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KXX77300.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAP2 PF01569.16 KXX77301.1 - 3.7e-13 49.2 3.8 3.7e-13 49.2 2.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KXX77301.1 - 4.3e-07 29.6 8.5 1.1e-06 28.3 5.9 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KXX77301.1 - 2.7 8.3 6.1 1.5 9.1 1.3 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RNA_polI_A34 PF08208.6 KXX77302.1 - 6.8e-26 91.1 0.3 6.8e-26 91.1 0.2 5.5 2 2 3 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 DAO PF01266.19 KXX77303.1 - 6.3e-59 199.6 0.5 8.7e-59 199.2 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX77303.1 - 2.8e-07 30.8 0.0 0.019 15.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX77303.1 - 3.9e-05 23.5 0.1 9.3e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KXX77303.1 - 0.00045 19.4 0.1 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX77303.1 - 0.00072 18.5 0.5 0.5 9.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KXX77303.1 - 0.0015 17.2 0.9 0.043 12.4 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KXX77303.1 - 0.0046 16.8 0.3 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KXX77303.1 - 0.033 13.2 0.4 0.064 12.3 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mqo PF06039.10 KXX77303.1 - 0.09 10.9 0.0 5.5 5.0 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 KXX77303.1 - 0.1 11.6 0.4 6.1 5.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KXX77303.1 - 0.15 11.1 0.2 0.83 8.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GSHPx PF00255.14 KXX77304.1 - 2.7e-41 139.3 0.0 3.3e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 KXX77304.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) AhpC-TSA PF00578.16 KXX77304.1 - 0.014 15.0 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 KXX77304.1 - 0.039 13.5 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 Redoxin YodL PF14191.1 KXX77304.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 YodL-like GFO_IDH_MocA PF01408.17 KXX77305.1 - 3.8e-10 40.3 0.3 9.7e-10 39.0 0.2 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KXX77305.1 - 0.088 13.2 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 KXX77305.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.17 KXX77306.1 - 3.5e-35 121.0 0.0 4e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Lipase_GDSL_2 PF13472.1 KXX77307.1 - 1.3e-17 64.5 0.2 1.6e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX77307.1 - 4.9e-13 49.4 0.1 6.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PFL PF02901.10 KXX77307.1 - 0.092 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase MFS_1 PF07690.11 KXX77309.1 - 3.8e-42 144.2 45.1 6.3e-42 143.5 31.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77309.1 - 7.5e-18 64.3 2.9 7.5e-18 64.3 2.0 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter Ank_2 PF12796.2 KXX77310.1 - 9.4e-46 154.0 2.1 2.5e-20 72.5 0.3 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77310.1 - 1.3e-36 122.5 4.4 5e-09 35.5 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KXX77310.1 - 4.8e-32 109.7 4.0 1.3e-12 47.8 0.0 5.2 2 1 4 6 6 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77310.1 - 3.9e-22 77.7 2.8 2.3e-09 37.2 0.0 4.9 3 1 2 5 5 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77310.1 - 4.4e-19 66.6 1.4 0.00059 19.8 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.7 KXX77310.1 - 8.4e-11 41.8 0.1 2.1e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX77310.1 - 2.4e-05 24.3 1.9 6.5e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KXX77310.1 - 3.2e-05 22.9 0.1 0.0047 15.8 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.1 KXX77310.1 - 0.0028 17.7 0.8 0.14 12.2 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KXX77310.1 - 0.093 12.6 0.0 0.36 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain ApoC-I PF04691.7 KXX77310.1 - 0.11 12.1 0.1 0.34 10.6 0.0 1.8 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Syntaxin_2 PF14523.1 KXX77310.1 - 0.21 11.6 8.8 0.5 10.4 0.7 3.6 3 1 0 3 3 3 0 Syntaxin-like protein EMP70 PF02990.11 KXX77311.1 - 0.018 13.5 0.4 0.022 13.2 0.3 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Sdh_cyt PF01127.17 KXX77311.1 - 0.052 13.3 0.5 0.089 12.6 0.4 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Git3 PF11710.3 KXX77312.1 - 0.019 14.5 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF2636 PF11120.3 KXX77312.1 - 0.097 12.1 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) TIMELESS PF04821.9 KXX77313.1 - 3.5e-94 314.9 0.0 1e-93 313.4 0.0 1.9 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KXX77313.1 - 1.2e-36 126.7 8.5 1.2e-36 126.7 5.9 5.3 5 2 0 5 5 5 1 Timeless protein C terminal region 3HCDH_N PF02737.13 KXX77314.1 - 3.1e-54 183.3 0.4 4.4e-54 182.8 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KXX77314.1 - 1.8e-33 114.7 0.0 3.6e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 KXX77314.1 - 0.00016 20.7 0.1 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KXX77314.1 - 0.00061 19.6 0.1 0.0015 18.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 KXX77314.1 - 0.0023 16.9 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX77314.1 - 0.0047 17.3 0.1 0.015 15.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KXX77314.1 - 0.0053 16.5 1.0 0.011 15.4 0.7 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KXX77314.1 - 0.012 14.8 0.3 0.044 12.9 0.2 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KXX77314.1 - 0.026 14.9 0.9 0.098 13.0 0.6 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 KXX77314.1 - 0.04 13.7 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX77314.1 - 0.053 13.5 0.9 0.13 12.3 0.6 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KXX77314.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KXX77314.1 - 0.066 13.2 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Homeobox PF00046.24 KXX77315.1 - 1.1e-17 63.3 2.8 2.1e-17 62.4 2.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KXX77315.1 - 0.0037 16.9 0.1 0.0083 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HLH PF00010.21 KXX77316.1 - 1.5e-12 46.9 0.8 1.5e-12 46.9 0.5 2.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Taxilin PF09728.4 KXX77316.1 - 0.00086 18.4 5.9 0.0012 18.0 4.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1664 PF07889.7 KXX77316.1 - 0.014 15.1 0.5 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 KXX77316.1 - 0.017 14.9 4.3 0.034 13.9 2.7 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.4 KXX77316.1 - 0.022 13.9 3.2 0.034 13.3 2.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF641 PF04859.7 KXX77316.1 - 0.027 14.2 3.1 0.057 13.1 2.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 KXX77316.1 - 0.048 14.0 3.5 0.062 13.6 0.4 2.5 2 0 0 2 2 2 0 SlyX DivIC PF04977.10 KXX77316.1 - 0.057 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX77316.1 - 0.096 12.2 7.5 0.057 13.0 3.7 1.6 1 1 0 1 1 1 0 IncA protein Nnf1 PF03980.9 KXX77316.1 - 0.13 12.2 3.3 0.34 10.9 2.3 1.8 1 0 0 1 1 1 0 Nnf1 FliJ PF02050.11 KXX77316.1 - 0.22 11.6 6.0 0.74 9.8 4.1 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein Fib_alpha PF08702.5 KXX77316.1 - 0.23 11.5 4.7 0.77 9.8 3.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 KXX77316.1 - 0.29 11.0 8.0 0.66 9.8 5.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KXX77316.1 - 0.63 8.9 10.8 1.7 7.5 7.5 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fungal_trans_2 PF11951.3 KXX77317.1 - 9.9e-79 264.6 0.0 1.2e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77317.1 - 1.7e-07 31.0 5.2 2.9e-07 30.2 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 KXX77318.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX77318.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KXX77318.1 - 0.0044 17.2 0.0 0.056 13.6 0.0 2.6 1 1 0 1 1 1 1 PH domain ORMDL PF04061.9 KXX77319.1 - 9.1e-61 203.3 3.5 1.1e-60 203.1 2.4 1.0 1 0 0 1 1 1 1 ORMDL family DHFR_2 PF06442.6 KXX77320.1 - 0.034 13.7 0.5 0.93 9.1 0.1 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase DUF202 PF02656.10 KXX77321.1 - 1.2e-25 89.4 2.1 1.2e-25 89.4 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aldo_ket_red PF00248.16 KXX77322.1 - 4.7e-51 173.2 0.0 6.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 KXX77322.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF530 PF04409.7 KXX77322.1 - 0.14 10.2 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) SHR3_chaperone PF08229.6 KXX77323.1 - 2.9e-65 218.9 0.0 3.5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4131 PF13567.1 KXX77323.1 - 0.0076 15.6 0.9 0.17 11.3 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Ni_hydr_CYTB PF01292.15 KXX77323.1 - 0.016 14.6 0.4 0.043 13.2 0.1 1.8 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KXX77323.1 - 0.047 13.0 1.4 0.15 11.3 0.1 2.3 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FAM163 PF15069.1 KXX77324.1 - 0.029 14.9 0.1 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 FAM163 family TMEM154 PF15102.1 KXX77324.1 - 0.048 13.3 0.2 0.077 12.6 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Myco_19_kDa PF05481.7 KXX77324.1 - 0.17 11.6 3.6 0.35 10.6 2.5 1.4 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Lipoprotein_6 PF01441.14 KXX77325.1 - 0.086 12.6 0.9 0.21 11.4 0.4 1.8 1 1 1 2 2 2 0 Lipoprotein Siah-Interact_N PF09032.6 KXX77325.1 - 0.086 12.9 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Siah interacting protein, N terminal HATPase_c PF02518.21 KXX77326.1 - 1.7e-28 98.5 0.0 5e-28 97.0 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KXX77326.1 - 9.6e-28 96.4 0.1 1.6e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KXX77326.1 - 1.8e-13 50.2 0.0 4.4e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KXX77326.1 - 0.00023 21.2 4.6 0.027 14.6 0.1 3.3 3 0 0 3 3 3 2 HAMP domain Aldo_ket_red PF00248.16 KXX77327.1 - 5.5e-10 38.5 0.0 7.6e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 KXX77328.1 - 2.1e-07 30.3 0.0 3.3e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KXX77328.1 - 2.1e-07 30.9 1.4 0.0055 16.4 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KXX77328.1 - 2.6e-06 26.6 0.0 0.00019 20.5 0.0 2.2 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KXX77328.1 - 0.0052 15.8 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KXX77328.1 - 0.0067 15.8 0.0 2.2 7.6 0.0 2.6 3 0 0 3 3 3 2 RIO1 family CMD PF02627.15 KXX77330.1 - 4.6e-09 35.9 0.4 1.6e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Maf1 PF09174.5 KXX77331.1 - 1.4e-63 213.9 0.1 2e-63 213.4 0.1 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 KXX77332.1 - 1.2e-51 174.2 1.5 1.4e-51 173.9 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain YchF-GTPase_C PF06071.8 KXX77333.1 - 3.4e-34 116.4 0.4 1.1e-33 114.8 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KXX77333.1 - 2.6e-12 46.7 0.0 5.3e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX77333.1 - 0.00053 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KXX77333.1 - 0.0012 18.6 0.1 0.0033 17.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain AAA_14 PF13173.1 KXX77333.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Minor_capsid_1 PF10665.4 KXX77333.1 - 0.057 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Minor capsid protein MobB PF03205.9 KXX77333.1 - 0.076 12.7 0.5 4 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 KXX77333.1 - 0.093 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 SecA preprotein cross-linking domain ABC_tran PF00005.22 KXX77333.1 - 0.97 9.7 3.4 4.7 7.5 0.1 2.7 2 1 0 2 2 2 0 ABC transporter VPS9 PF02204.13 KXX77334.1 - 2e-19 69.5 0.0 4.9e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KXX77334.1 - 8.4e-18 64.0 0.2 7.7e-11 41.8 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX77334.1 - 1.8e-11 44.1 0.1 0.0057 17.1 0.0 5.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX77334.1 - 2.4e-11 43.7 0.0 7.1e-07 29.4 0.0 3.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX77334.1 - 1.9e-09 36.8 0.0 0.014 15.5 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 KXX77334.1 - 3.7e-07 29.6 0.2 0.046 13.5 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeat PX PF00787.19 KXX77334.1 - 0.00045 20.0 0.1 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 1 PX domain gp37_C PF12604.3 KXX77334.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal DUF4623 PF15416.1 KXX77334.1 - 0.26 9.5 0.0 0.47 8.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) 3Beta_HSD PF01073.14 KXX77335.1 - 1.8e-20 72.8 0.0 5.4e-20 71.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX77335.1 - 1.4e-13 50.8 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX77335.1 - 9.9e-08 31.2 0.0 7.4e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KXX77335.1 - 1.6e-07 31.4 0.0 1.9e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX77335.1 - 1.8e-06 27.9 0.5 4.6e-06 26.6 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77335.1 - 0.00029 20.5 0.0 0.00061 19.5 0.0 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KXX77335.1 - 0.048 13.6 0.0 0.38 10.7 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain Peptidase_C97 PF05903.9 KXX77336.1 - 4.7e-35 120.5 0.0 5.7e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KXX77336.1 - 9.2e-05 22.4 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase AAA_11 PF13086.1 KXX77337.1 - 3.9e-58 196.8 0.1 1e-57 195.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KXX77337.1 - 1.4e-55 187.7 0.0 3.9e-55 186.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX77337.1 - 6.4e-12 45.0 2.4 9.5e-12 44.5 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 KXX77337.1 - 1.3e-09 37.9 0.0 5.7e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KXX77337.1 - 5.6e-07 29.5 0.0 1.5e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KXX77337.1 - 1.2e-06 27.8 0.1 8e-06 25.0 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KXX77337.1 - 1.6e-06 27.7 0.0 0.61 9.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KXX77337.1 - 2.7e-05 23.6 0.0 0.00012 21.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KXX77337.1 - 0.00021 21.4 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX77337.1 - 0.0023 17.3 0.1 0.027 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 KXX77337.1 - 0.0024 17.4 0.0 0.018 14.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KXX77337.1 - 0.0025 17.0 0.0 0.057 12.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KXX77337.1 - 0.0026 16.7 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KXX77337.1 - 0.003 17.3 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain Zot PF05707.7 KXX77337.1 - 0.0041 16.6 0.0 0.053 12.9 0.0 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KXX77337.1 - 0.0043 16.5 0.0 0.04 13.3 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA PF00004.24 KXX77337.1 - 0.0044 17.2 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX77337.1 - 0.0045 16.9 0.8 0.011 15.7 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain UvrD_C PF13361.1 KXX77337.1 - 0.0063 16.0 0.1 3.8 6.8 0.0 3.0 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 KXX77337.1 - 0.01 16.6 1.3 0.56 11.0 0.5 3.0 2 1 0 2 2 2 0 AAA domain 4HB_MCP_1 PF12729.2 KXX77337.1 - 0.016 14.5 0.1 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_33 PF13671.1 KXX77337.1 - 0.02 14.7 0.0 0.33 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KXX77337.1 - 0.025 14.3 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KXX77337.1 - 0.029 13.8 0.0 0.072 12.5 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KXX77337.1 - 0.034 12.7 0.0 0.058 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.1 KXX77337.1 - 0.071 13.2 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Lzipper-MIP1 PF14389.1 KXX77338.1 - 0.0043 17.1 0.8 0.012 15.6 0.2 2.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 KXX77338.1 - 0.16 11.4 2.5 0.39 10.2 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator NOGCT PF08155.6 KXX77339.1 - 1.1e-28 98.6 2.0 2.2e-28 97.7 1.4 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KXX77339.1 - 5.7e-28 96.5 0.3 1.2e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KXX77339.1 - 3.4e-10 39.9 0.0 7.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Acetyltransf_1 PF00583.19 KXX77339.1 - 1.4e-07 31.4 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FeoB_N PF02421.13 KXX77339.1 - 3.2e-06 26.5 0.0 5.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Acetyltransf_7 PF13508.1 KXX77339.1 - 3.9e-05 23.7 0.0 8.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Miro PF08477.8 KXX77339.1 - 0.00088 19.7 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Acetyltransf_10 PF13673.1 KXX77339.1 - 0.025 14.6 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 KXX77340.1 - 8.3e-15 54.6 0.4 1.5e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans_2 PF11951.3 KXX77341.1 - 6.7e-16 57.8 2.7 1.3e-14 53.6 1.9 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77341.1 - 4.7e-09 36.0 10.7 7.8e-09 35.3 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX77341.1 - 1.9e-05 23.6 0.1 6.3e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Proteasome PF00227.21 KXX77342.1 - 5.3e-57 192.1 0.2 6.7e-57 191.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX77342.1 - 1e-13 50.3 0.0 2.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FA_desaturase PF00487.19 KXX77343.1 - 2.8e-17 63.0 9.5 2.8e-17 63.0 6.6 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KXX77343.1 - 7.4e-17 60.9 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.18 KXX77344.1 - 7.7e-05 22.5 0.1 0.012 15.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Baculo_LEF-10 PF07206.6 KXX77344.1 - 0.089 12.4 0.2 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) HAD_2 PF13419.1 KXX77345.1 - 1.1e-33 116.8 0.3 1.4e-33 116.5 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX77345.1 - 7.9e-09 35.1 0.0 1.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KXX77345.1 - 1.8e-05 25.2 0.0 8.5e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KXX77345.1 - 0.012 15.2 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase HAD PF12710.2 KXX77345.1 - 0.021 15.0 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SelP_N PF04592.9 KXX77346.1 - 1.4 8.1 14.3 3.8 6.8 9.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KXX77346.1 - 1.7 7.5 13.7 0.014 14.3 3.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2034 PF10356.4 KXX77347.1 - 1.1e-24 86.5 0.0 9e-23 80.3 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KXX77347.1 - 7.3e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 KXX77348.1 - 4.3e-44 149.9 1.7 4.8e-44 149.8 1.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 KXX77348.1 - 0.0039 16.3 1.8 0.61 9.2 0.3 2.4 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.8 KXX77348.1 - 0.0042 16.7 2.4 0.011 15.4 0.5 2.5 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 KXX77348.1 - 0.66 9.8 6.3 0.17 11.7 2.0 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KXX77348.1 - 2.9 7.4 7.4 4.7 6.7 5.1 1.6 1 1 0 1 1 1 0 IncA protein Lon_C PF05362.8 KXX77349.1 - 2.4e-64 216.4 0.0 4.9e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KXX77349.1 - 7.4e-36 123.7 0.0 2.1e-35 122.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KXX77349.1 - 4e-22 78.8 0.0 9.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KXX77349.1 - 6.6e-09 35.3 0.0 1.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KXX77349.1 - 4.4e-07 29.7 0.0 8.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX77349.1 - 1.8e-06 27.9 0.0 4.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KXX77349.1 - 1.8e-05 24.8 0.0 0.00031 20.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77349.1 - 2.3e-05 24.4 2.6 0.0091 16.0 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.6 KXX77349.1 - 4.7e-05 22.2 0.0 9.6e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KXX77349.1 - 8.2e-05 23.4 0.0 0.00032 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX77349.1 - 0.00014 20.9 0.0 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KXX77349.1 - 0.0079 16.5 0.6 0.029 14.6 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.1 KXX77349.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KXX77349.1 - 0.035 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 KXX77349.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KXX77349.1 - 0.043 13.0 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KXX77349.1 - 0.044 13.9 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 KXX77349.1 - 0.051 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KXX77349.1 - 0.062 12.9 0.1 1 9.0 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 KXX77349.1 - 0.065 12.6 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX77349.1 - 0.7 10.1 3.5 0.83 9.9 0.0 2.7 3 0 0 3 3 3 0 ABC transporter Med19 PF10278.4 KXX77350.1 - 0.062 12.9 0.4 0.062 12.9 0.2 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Hamartin PF04388.7 KXX77350.1 - 0.45 9.1 6.9 0.55 8.8 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein DUF605 PF04652.11 KXX77350.1 - 3 7.1 11.3 3.6 6.9 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Apis_Csd PF11671.3 KXX77350.1 - 3.7 7.3 6.8 5.9 6.6 4.7 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Synaphin PF05835.7 KXX77350.1 - 8.8 6.4 17.1 32 4.6 0.1 2.1 2 0 0 2 2 2 0 Synaphin protein TAF1D PF15333.1 KXX77350.1 - 9.7 5.9 9.6 0.62 9.8 0.3 2.1 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Pkinase PF00069.20 KXX77352.1 - 6.1e-14 51.7 0.1 1.2e-12 47.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77352.1 - 2.1e-13 49.9 0.0 2.1e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Asp_protease PF09668.5 KXX77353.1 - 5.9e-59 197.0 0.1 8.4e-59 196.5 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KXX77353.1 - 2.3e-11 44.0 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 KXX77353.1 - 7.8e-08 31.9 0.1 2.5e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain gag-asp_proteas PF13975.1 KXX77353.1 - 1.5e-07 31.1 0.0 3.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.18 KXX77353.1 - 4.8e-07 29.0 0.0 9.6e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 KXX77353.1 - 6e-06 26.2 0.0 9.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KXX77353.1 - 6.6e-05 22.7 0.0 0.00024 20.9 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 KXX77353.1 - 0.00014 21.2 0.1 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.3 KXX77353.1 - 0.0011 19.1 0.1 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 KXX77353.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Methyltransf_23 PF13489.1 KXX77354.1 - 4.2e-14 52.5 0.0 7.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77354.1 - 3.5e-11 43.4 0.0 1.2e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77354.1 - 7.9e-09 35.2 0.0 3.5e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77354.1 - 6.3e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77354.1 - 1.6e-06 28.6 0.0 3e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX77354.1 - 4.5e-05 23.4 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX77354.1 - 7.7e-05 21.8 0.0 0.00018 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KXX77354.1 - 0.0002 21.6 0.0 0.00059 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KXX77354.1 - 0.027 12.8 0.0 0.041 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 KXX77354.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase SNF2_N PF00176.18 KXX77355.1 - 5.7e-71 238.7 0.1 7.7e-71 238.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX77355.1 - 1.3e-09 37.8 0.0 3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 KXX77355.1 - 5.8e-06 26.1 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 KXX77355.1 - 1.2e-05 24.8 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase WW PF00397.21 KXX77355.1 - 0.026 14.3 0.5 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 WW domain zf-RING_5 PF14634.1 KXX77355.1 - 0.1 12.3 8.9 0.2 11.4 6.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX77355.1 - 0.6 10.0 5.4 1.4 8.8 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KXX77355.1 - 1.6 8.4 8.5 3.1 7.5 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YqeY PF09424.5 KXX77356.1 - 1.4e-16 60.6 8.2 1.4e-16 60.6 5.7 1.8 2 0 0 2 2 2 1 Yqey-like protein DUF3752 PF12572.3 KXX77356.1 - 0.78 9.8 4.6 0.14 12.2 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) Spc97_Spc98 PF04130.8 KXX77357.1 - 5e-130 434.3 1.0 7.2e-130 433.8 0.7 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family KH_1 PF00013.24 KXX77358.1 - 8.6e-25 86.1 3.8 1.6e-07 30.8 0.1 6.4 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 KXX77358.1 - 1.2e-21 75.8 6.2 9.3e-05 21.9 0.2 5.9 6 0 0 6 6 6 5 KH domain GDI PF00996.13 KXX77359.1 - 6.5e-17 60.9 0.0 7.5e-17 60.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Methyltransf_8 PF05148.10 KXX77360.1 - 2.9e-56 190.5 0.0 5.7e-55 186.3 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KXX77360.1 - 1.1e-07 32.2 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77360.1 - 0.004 16.7 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 KXX77360.1 - 0.067 12.5 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KXX77360.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Daxx PF03344.10 KXX77360.1 - 0.19 10.1 20.0 0.29 9.5 13.8 1.2 1 0 0 1 1 1 0 Daxx Family 7tm_2 PF00002.19 KXX77361.1 - 1.2e-12 47.4 3.8 1.2e-12 47.4 2.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KXX77361.1 - 2.2e-12 46.4 8.6 2.2e-12 46.4 6.0 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KXX77361.1 - 1.1e-07 31.6 9.9 1.1e-07 31.6 6.9 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KXX77361.1 - 6.8e-06 25.4 2.6 1.2e-05 24.6 1.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Peptidase_C12 PF01088.16 KXX77362.1 - 3.4e-72 242.1 0.0 4.8e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_L22 PF00237.14 KXX77363.1 - 4e-34 116.7 0.0 5.8e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 KXX77364.1 - 1.2e-106 354.7 0.0 1.5e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KXX77364.1 - 3.2e-06 26.8 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KXX77364.1 - 0.0039 16.7 0.1 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KXX77364.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-rbx1 PF12678.2 KXX77366.1 - 4.1e-12 46.0 1.5 7.4e-12 45.2 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KXX77366.1 - 1.6e-11 43.8 4.8 2.8e-11 43.0 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX77366.1 - 1.5e-07 30.9 3.6 3.7e-07 29.6 2.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX77366.1 - 5.2e-06 26.0 2.2 1e-05 25.1 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX77366.1 - 6.3e-06 25.7 3.5 1.1e-05 24.9 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX77366.1 - 8.4e-06 25.7 3.1 2.8e-05 24.0 2.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX77366.1 - 0.00031 20.5 0.5 0.00065 19.4 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KXX77366.1 - 0.0028 17.3 2.4 0.0078 15.9 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KXX77366.1 - 0.0069 15.9 0.3 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KXX77366.1 - 0.5 9.9 2.7 1.1 8.8 1.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KXX77366.1 - 2 8.4 5.0 2 8.4 2.0 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain PS_Dcarbxylase PF02666.10 KXX77367.1 - 2e-82 275.3 0.0 5.7e-81 270.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.18 KXX77368.1 - 9.2e-07 28.1 0.0 2.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KXX77368.1 - 1.8e-06 28.0 0.1 1.8e-06 28.0 0.1 2.6 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 KXX77368.1 - 0.093 12.4 0.0 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like FAD_binding_1 PF00667.15 KXX77369.1 - 7.1e-44 149.8 0.0 9.8e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KXX77369.1 - 9.1e-10 39.0 0.0 3.1e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 KXX77370.1 - 7.9e-15 55.0 0.0 9.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family adh_short PF00106.20 KXX77371.1 - 1.5e-26 93.3 6.6 2.1e-26 92.7 4.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX77371.1 - 1.4e-23 83.9 0.0 1.9e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX77371.1 - 1.6e-13 50.7 3.0 2.4e-13 50.1 2.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX77371.1 - 0.024 14.4 2.6 0.18 11.6 0.3 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase N2227 PF07942.7 KXX77372.1 - 1e-98 329.6 0.0 1.2e-98 329.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KXX77372.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77372.1 - 0.00067 20.0 0.0 0.0039 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77372.1 - 0.0081 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77372.1 - 0.019 15.5 0.0 0.12 12.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77372.1 - 0.094 12.2 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KXX77373.1 - 1.4e-05 24.6 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase zf-C2H2 PF00096.21 KXX77376.1 - 0.00018 21.6 19.6 0.95 9.9 0.5 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX77376.1 - 0.00041 20.4 16.3 0.13 12.6 0.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KXX77376.1 - 0.0068 16.2 1.3 0.069 13.0 0.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 KXX77376.1 - 0.085 11.3 0.1 0.43 9.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF629) HEAT_EZ PF13513.1 KXX77377.1 - 1.1e-25 89.3 16.7 3.8e-15 55.8 0.0 11.6 8 2 6 14 14 14 4 HEAT-like repeat HEAT_2 PF13646.1 KXX77377.1 - 2.5e-23 82.1 1.5 5.4e-07 29.8 0.0 8.1 3 3 6 9 9 9 6 HEAT repeats HEAT PF02985.17 KXX77377.1 - 2.2e-22 77.0 20.7 1.1e-05 25.0 0.0 10.1 13 1 0 13 13 12 5 HEAT repeat MMS19_C PF12460.3 KXX77377.1 - 7.5e-12 44.6 1.7 0.0015 17.3 0.0 5.3 5 1 1 6 6 6 4 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 KXX77377.1 - 2.2e-08 34.3 0.0 0.075 13.4 0.0 6.3 5 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KXX77377.1 - 8e-06 25.6 1.5 0.00043 20.1 0.3 4.1 2 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KXX77377.1 - 0.00015 21.1 0.3 4.3 6.6 0.0 6.3 7 3 2 9 9 9 1 CLASP N terminal Arm PF00514.18 KXX77377.1 - 0.00072 19.2 5.7 0.11 12.3 0.0 5.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KXX77377.1 - 0.0075 15.9 0.8 6 6.5 0.0 4.5 5 2 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF4303 PF14136.1 KXX77377.1 - 0.026 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) HEAT_PBS PF03130.11 KXX77377.1 - 0.1 13.1 5.4 3 8.5 0.0 5.0 5 0 0 5 5 2 0 PBS lyase HEAT-like repeat Speriolin_N PF15058.1 KXX77378.1 - 0.013 15.3 3.0 0.28 11.0 2.1 2.0 1 1 0 1 1 1 0 Speriolin N terminus Ank_4 PF13637.1 KXX77379.1 - 8.1e-39 131.3 1.9 8e-09 35.7 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX77379.1 - 1e-36 125.1 0.4 1.6e-15 57.2 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77379.1 - 6.2e-35 117.2 0.3 1.3e-08 34.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KXX77379.1 - 3.8e-26 90.5 2.7 1.6e-05 24.9 0.1 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77379.1 - 4.8e-22 75.8 0.0 0.0022 18.0 0.0 6.3 7 0 0 7 7 7 5 Ankyrin repeat YlbE PF14003.1 KXX77379.1 - 0.16 12.0 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 YlbE-like protein HET PF06985.6 KXX77380.1 - 1.7e-05 24.9 0.0 1.9e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2296 PF10058.4 KXX77381.1 - 5.8e-19 67.5 0.1 9.6e-19 66.8 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF3325 PF11804.3 KXX77381.1 - 0.15 11.9 1.5 0.28 11.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) GRIP PF01465.15 KXX77382.1 - 8.7e-16 57.1 0.2 1.8e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 KXX77382.1 - 2.7e-05 23.8 152.3 0.1 12.1 13.6 8.4 3 2 5 8 8 8 5 IncA protein DivIC PF04977.10 KXX77382.1 - 0.00018 20.9 1.5 0.00018 20.9 1.0 14.4 7 3 10 17 17 17 6 Septum formation initiator CENP-F_leu_zip PF10473.4 KXX77382.1 - 0.00019 21.3 163.7 0.034 14.0 8.9 9.4 3 2 6 9 9 9 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KXX77382.1 - 0.00021 18.8 20.6 0.00021 18.8 14.3 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KXX77382.1 - 0.00047 19.4 49.5 0.055 12.6 4.3 7.1 3 2 6 9 9 9 5 Reovirus sigma C capsid protein WEMBL PF05701.6 KXX77382.1 - 0.0011 17.5 41.7 0.0011 17.5 28.9 4.6 2 2 2 4 4 3 1 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 KXX77382.1 - 0.0013 18.5 4.6 0.0013 18.5 3.2 7.7 4 3 4 8 8 8 3 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 KXX77382.1 - 0.0039 16.6 7.5 0.0039 16.6 5.2 11.1 4 3 5 11 11 10 2 Phage minor structural protein GP20 GAS PF13851.1 KXX77382.1 - 0.0095 15.1 144.5 0.29 10.3 10.1 9.2 3 2 4 8 8 8 5 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 KXX77382.1 - 0.015 13.0 158.0 0.0093 13.7 17.6 5.0 3 1 0 4 4 4 0 Myosin tail DUF869 PF05911.6 KXX77382.1 - 0.069 11.3 107.2 0.0067 14.7 12.4 4.9 3 1 2 5 5 5 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 KXX77382.1 - 0.076 11.4 111.6 0.0059 15.1 15.3 5.5 3 1 2 5 5 5 0 AAA domain APG6 PF04111.7 KXX77382.1 - 9.7 5.1 148.7 0.87 8.5 16.6 8.3 3 2 5 8 8 8 0 Autophagy protein Apg6 Peptidase_M16_C PF05193.16 KXX77385.1 - 9.8e-33 113.3 0.1 3.7e-17 62.6 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KXX77385.1 - 5e-28 97.7 1.2 2.5e-27 95.4 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GFA PF04828.9 KXX77388.1 - 1.4e-15 56.9 15.9 7.6e-09 35.4 0.1 4.0 5 0 0 5 5 5 3 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KXX77388.1 - 0.0047 16.7 1.8 1.2 9.0 0.3 2.7 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.11 KXX77388.1 - 1.3 8.9 4.7 4 7.3 0.0 3.2 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Xan_ur_permease PF00860.15 KXX77389.1 - 1.6e-26 92.7 31.2 1.6e-24 86.1 20.3 3.0 2 1 0 2 2 2 2 Permease family Zn_clus PF00172.13 KXX77390.1 - 0.053 13.4 9.1 0.099 12.5 6.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 KXX77391.1 - 2e-22 78.7 0.0 5.8e-22 77.2 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KXX77391.1 - 0.00026 20.8 0.2 0.0064 16.3 0.0 2.5 1 1 1 2 2 2 1 Bd3614-like deaminase Zn_clus PF00172.13 KXX77392.1 - 0.066 13.1 3.5 0.13 12.1 2.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain vMSA PF00695.14 KXX77392.1 - 1.2 8.2 3.8 1.3 8.1 2.6 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF1656 PF07869.7 KXX77393.1 - 0.065 13.0 0.5 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) SH3_9 PF14604.1 KXX77394.1 - 4.1e-12 45.4 0.1 7.3e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 KXX77394.1 - 6.6e-12 45.4 0.1 1e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KXX77394.1 - 1.8e-11 43.2 0.1 3.3e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX77394.1 - 7.4e-09 34.9 0.1 1.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2439 PF10382.4 KXX77395.1 - 3.9e-28 97.4 0.2 5.9e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Antitoxin-MazE PF04014.13 KXX77395.1 - 0.056 13.1 0.6 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 Antidote-toxin recognition MazE AKAP28 PF14469.1 KXX77395.1 - 0.25 10.9 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor WD40 PF00400.27 KXX77396.1 - 1.3e-10 40.7 2.4 0.00026 20.7 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat PD40 PF07676.7 KXX77396.1 - 0.001 18.6 0.6 0.046 13.3 0.1 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KXX77396.1 - 0.12 12.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HgmA PF04209.8 KXX77397.1 - 2.8e-104 348.8 0.0 3.2e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase BTB PF00651.26 KXX77398.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Ribosomal_S10 PF00338.17 KXX77400.1 - 2.2e-28 97.9 0.5 2.6e-28 97.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L17 PF01196.14 KXX77400.1 - 0.12 12.9 1.0 0.15 12.6 0.7 1.3 1 1 0 1 1 1 0 Ribosomal protein L17 TauD PF02668.11 KXX77401.1 - 3.2e-53 181.0 0.0 4.4e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KXX77401.1 - 0.0041 17.6 0.0 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 KXX77401.1 - 0.0098 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KXX77401.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 CsiD Gly_transf_sug PF04488.10 KXX77402.1 - 8.9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Band_7 PF01145.20 KXX77403.1 - 1.2e-12 48.1 0.4 1.2e-12 48.1 0.3 3.7 2 2 0 2 2 2 1 SPFH domain / Band 7 family DUF3986 PF13143.1 KXX77403.1 - 0.22 12.0 1.1 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) MFS_1 PF07690.11 KXX77404.1 - 8e-43 146.4 56.9 2e-42 145.2 39.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX77404.1 - 2.3e-13 49.2 23.3 3.6e-13 48.6 16.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX77404.1 - 1.6e-12 46.7 13.2 1.6e-12 46.7 9.2 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter U3_assoc_6 PF08640.6 KXX77406.1 - 2e-24 85.1 0.6 5.2e-24 83.8 0.4 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KXX77406.1 - 0.0033 17.9 11.0 0.0046 17.4 0.7 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77406.1 - 0.017 14.7 0.5 0.067 12.8 0.3 2.1 1 1 1 2 2 2 0 TPR repeat NRDE-2 PF08424.5 KXX77406.1 - 0.12 11.2 1.4 0.47 9.2 0.0 2.4 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference Glyco_hydro_72 PF03198.9 KXX77407.1 - 1.1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Frag1 PF10277.4 KXX77408.1 - 1.6e-42 145.4 12.8 9.4e-42 142.9 5.6 2.8 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KXX77408.1 - 0.00069 19.6 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_68 PF02435.11 KXX77408.1 - 0.29 9.7 0.5 0.52 8.9 0.3 1.3 1 0 0 1 1 1 0 Levansucrase/Invertase p450 PF00067.17 KXX77409.1 - 2.6e-66 224.0 0.0 3.4e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3649 PF12365.3 KXX77409.1 - 0.019 14.4 1.6 0.045 13.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) Cellulase PF00150.13 KXX77410.1 - 1.2e-21 77.1 0.7 3.7e-21 75.5 0.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.7 KXX77410.1 - 0.024 14.2 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Mpv17 / PMP22 family OTT_1508_deam PF14441.1 KXX77411.1 - 3.1e-15 56.2 0.0 5.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase EVE PF01878.13 KXX77413.1 - 3e-52 176.4 0.1 4.3e-52 175.9 0.1 1.2 1 0 0 1 1 1 1 EVE domain 4HBT_3 PF13622.1 KXX77414.1 - 1.1e-37 130.1 1.6 1.4e-37 129.8 1.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KXX77414.1 - 0.055 13.5 0.1 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily IRS PF02174.12 KXX77414.1 - 0.12 12.0 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 PTB domain (IRS-1 type) CHORD PF04968.7 KXX77416.1 - 0.097 12.9 0.8 0.097 12.9 0.6 2.6 2 1 0 2 2 2 0 CHORD CUE PF02845.11 KXX77417.1 - 3.8e-10 39.0 0.0 1.4e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 CUE domain zf-CCCH PF00642.19 KXX77418.1 - 2.3e-07 30.3 4.1 4e-07 29.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sulfate_transp PF00916.15 KXX77419.1 - 3.1e-66 223.2 8.1 5.6e-66 222.4 5.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX77419.1 - 1.4e-30 104.7 5.4 1.4e-30 104.7 3.8 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif Pyr_redox_dim PF02852.17 KXX77420.1 - 6e-27 93.8 0.0 1.9e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KXX77420.1 - 8.9e-21 74.0 0.3 2.5e-20 72.6 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX77420.1 - 1.9e-20 73.6 3.9 1.7e-18 67.2 2.7 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX77420.1 - 3.6e-06 27.2 0.0 0.08 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX77420.1 - 9.6e-05 21.4 5.5 0.05 12.5 0.2 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KXX77420.1 - 0.00017 21.3 0.1 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KXX77420.1 - 0.00018 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 KXX77420.1 - 0.0012 18.7 0.4 0.12 12.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KXX77420.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.9 KXX77420.1 - 0.0015 17.0 0.4 0.74 8.2 0.0 2.5 1 1 1 2 2 2 2 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KXX77420.1 - 0.007 15.7 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KXX77420.1 - 0.011 15.7 0.1 0.041 13.8 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KXX77420.1 - 0.011 14.9 0.1 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 KXX77420.1 - 0.059 13.6 0.2 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.19 KXX77420.1 - 0.1 11.3 2.4 1.4 7.7 0.1 2.8 1 1 2 3 3 3 0 FAD binding domain ABC_tran PF00005.22 KXX77424.1 - 3.6e-49 166.5 0.0 4.9e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX77424.1 - 9.8e-31 107.1 28.2 2.1e-20 73.2 5.6 3.7 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KXX77424.1 - 2.5e-09 36.7 0.0 0.00022 20.5 0.0 4.2 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KXX77424.1 - 4.7e-06 26.1 0.0 0.0048 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX77424.1 - 0.00014 21.8 1.7 0.02 14.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KXX77424.1 - 0.00016 21.1 0.8 0.61 9.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KXX77424.1 - 0.00024 20.0 0.0 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 KXX77424.1 - 0.00071 19.9 0.1 0.039 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KXX77424.1 - 0.0028 17.6 2.6 2.4 8.0 0.0 4.2 4 1 1 5 5 5 1 AAA domain DUF258 PF03193.11 KXX77424.1 - 0.0098 15.0 0.2 3.6 6.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KXX77424.1 - 0.015 15.2 0.1 0.54 10.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KXX77424.1 - 0.02 15.0 1.0 18 5.4 0.0 3.4 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KXX77424.1 - 0.032 14.1 0.0 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KXX77424.1 - 0.033 14.6 1.5 5.4 7.5 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein DUF87 PF01935.12 KXX77424.1 - 0.056 13.2 3.1 0.98 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KXX77424.1 - 0.17 10.8 0.2 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SprT-like PF10263.4 KXX77425.1 - 5.1e-14 52.2 0.0 8.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 SprT-like family TraY PF05509.6 KXX77425.1 - 0.094 12.5 0.3 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 TraY domain Pkinase PF00069.20 KXX77427.1 - 1.7e-15 56.8 0.0 2.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77427.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.27 KXX77428.1 - 3.9e-29 99.4 9.0 2e-08 33.7 0.0 7.2 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KXX77428.1 - 0.00021 21.0 0.1 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Amidase PF01425.16 KXX77429.1 - 9e-80 268.6 0.0 1.1e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.7 KXX77429.1 - 0.0014 19.0 0.1 0.02 15.3 0.0 2.8 3 1 1 4 4 4 1 Methyltransferase domain MaoC_dehydratas PF01575.14 KXX77430.1 - 6.5e-20 70.7 0.0 1e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KXX77430.1 - 1.1e-05 25.2 0.0 0.00043 20.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Endothelin PF00322.12 KXX77431.1 - 0.7 9.1 3.6 2 7.7 1.6 2.0 2 0 0 2 2 2 0 Endothelin family PI-PLC-X PF00388.14 KXX77432.1 - 7.7e-10 38.3 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CAP_GLY PF01302.20 KXX77434.1 - 3.4e-19 68.2 0.0 7.2e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KXX77434.1 - 2.6e-16 58.8 3.1 0.0017 17.9 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX77434.1 - 1.4e-09 37.5 4.1 0.003 17.2 0.2 4.6 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 KXX77434.1 - 3.6e-07 29.3 5.2 8.9 6.7 0.1 7.2 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KXX77434.1 - 3.6e-06 26.4 6.6 11 6.4 0.0 7.7 7 1 1 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 KXX77434.1 - 0.0003 20.5 7.9 25 5.6 0.0 6.9 8 0 0 8 8 8 0 Leucine rich repeat LRR_9 PF14580.1 KXX77434.1 - 0.035 13.6 0.7 2.2 7.8 0.0 3.4 3 1 1 4 4 4 0 Leucine-rich repeat Sds3 PF08598.6 KXX77435.1 - 4.7e-28 98.1 4.2 4.7e-28 98.1 2.9 3.5 2 2 0 2 2 2 1 Sds3-like RRM_1 PF00076.17 KXX77436.1 - 5.9e-12 45.0 0.0 1.9e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77436.1 - 5.5e-11 42.1 0.0 3.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77436.1 - 5.7e-08 32.6 0.1 4.4e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.20 KXX77437.1 - 1.2e-65 221.3 0.0 1.6e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KXX77437.1 - 1.9e-42 144.3 0.0 2.9e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KXX77437.1 - 0.00031 20.2 0.0 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GPI-anchored PF10342.4 KXX77438.1 - 1.5e-19 70.2 0.1 1.5e-19 70.2 0.1 3.0 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF572 PF04502.8 KXX77438.1 - 0.054 12.7 1.7 0.067 12.4 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 KXX77438.1 - 0.071 11.9 2.0 0.088 11.6 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.7 KXX77438.1 - 6.3 5.0 10.1 8.3 4.6 7.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coiled-coil_56 PF09813.4 KXX77439.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 KXX77440.1 - 1.8e-72 243.6 0.0 3.1e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) MFS_1 PF07690.11 KXX77441.1 - 8.8e-22 77.2 45.3 3.3e-19 68.8 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77441.1 - 1.3e-14 53.6 20.8 9.6e-14 50.7 14.4 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2347 PF09804.4 KXX77442.1 - 0.19 10.9 1.4 0.27 10.4 0.4 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) zf-CCCH PF00642.19 KXX77443.1 - 6.8e-18 63.9 30.7 9.5e-07 28.3 0.2 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KXX77443.1 - 0.026 14.5 0.2 0.026 14.5 0.2 5.0 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type DUF1776 PF08643.5 KXX77444.1 - 3.1e-115 384.4 0.0 3.9e-115 384.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF1772 PF08592.6 KXX77445.1 - 2.8e-22 78.9 5.7 3.5e-22 78.6 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Virul_fac_BrkB PF03631.10 KXX77445.1 - 0.069 12.4 5.3 0.1 11.9 3.7 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Trp_oprn_chp PF09534.5 KXX77445.1 - 0.33 10.5 9.1 0.44 10.1 6.3 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Polysacc_synt_C PF14667.1 KXX77445.1 - 5.8 6.7 9.4 0.16 11.8 1.7 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain ADH_zinc_N PF00107.21 KXX77446.1 - 6.7e-35 119.4 1.2 6.7e-35 119.4 0.8 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KXX77446.1 - 1.6e-27 96.7 1.0 2.9e-27 95.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX77446.1 - 4e-18 65.5 2.2 4.4e-16 59.0 0.3 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX77446.1 - 3.9e-12 46.6 0.0 8.3e-08 32.5 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 KXX77446.1 - 1.2e-11 45.6 0.5 4e-11 43.9 0.1 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX77446.1 - 7.3e-06 25.7 0.0 3.3e-05 23.5 0.0 2.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAO PF01266.19 KXX77446.1 - 3e-05 23.1 4.2 0.53 9.1 0.1 4.4 4 1 1 5 5 5 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX77446.1 - 7.1e-05 23.0 0.9 0.0094 16.1 0.1 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KXX77446.1 - 7.3e-05 22.7 0.1 0.025 14.5 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX77446.1 - 0.0001 21.4 0.4 0.0016 17.5 0.0 2.8 3 1 1 4 4 4 1 Thi4 family GIDA PF01134.17 KXX77446.1 - 0.00059 18.7 1.0 0.78 8.5 0.1 3.9 4 0 0 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 KXX77446.1 - 0.0019 18.3 0.3 1.3 9.0 0.0 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KXX77446.1 - 0.0022 17.0 1.4 6.9 5.6 0.1 3.2 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 KXX77446.1 - 0.0027 16.8 0.3 0.042 12.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KXX77446.1 - 0.0031 16.4 0.1 0.6 8.9 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KXX77446.1 - 0.0066 16.0 5.3 0.33 10.5 0.7 3.9 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KXX77446.1 - 0.067 13.2 3.6 0.19 11.7 0.1 3.2 4 1 0 4 4 3 0 TrkA-N domain Trp_halogenase PF04820.9 KXX77446.1 - 0.067 11.8 0.7 0.75 8.3 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KXX77446.1 - 0.15 10.9 10.1 0.12 11.1 0.2 3.8 3 2 1 5 5 5 0 FAD binding domain Rab5ip PF07019.7 KXX77447.1 - 2.6e-24 85.1 4.7 3.5e-24 84.7 3.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.2 KXX77448.1 - 4.2e-64 216.0 0.1 1.2e-63 214.5 0.0 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Zn_clus PF00172.13 KXX77449.1 - 3.5e-08 33.2 10.3 5.6e-08 32.5 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX77449.1 - 0.00011 20.9 0.5 0.00019 20.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.15 KXX77450.1 - 3.4e-138 460.1 0.6 3.8e-138 459.9 0.4 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KXX77450.1 - 4.3e-07 29.2 0.2 6.5e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX77450.1 - 4.3e-07 28.9 1.4 6.4e-07 28.4 0.4 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KXX77450.1 - 1.8e-06 27.2 0.3 3.2e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KXX77450.1 - 6.4e-05 22.2 0.4 0.00011 21.4 0.3 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KXX77450.1 - 0.0016 17.2 0.2 0.0016 17.2 0.1 1.5 2 0 0 2 2 2 1 Glycine cleavage system P-protein KH_1 PF00013.24 KXX77452.1 - 2.7e-41 139.0 6.6 1.3e-16 59.9 0.6 3.5 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KXX77452.1 - 5.6e-31 105.6 13.6 2.6e-11 42.9 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KXX77452.1 - 5.1e-13 48.3 5.2 0.0019 17.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KXX77452.1 - 7.6e-05 22.2 2.6 0.94 9.1 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KXX77452.1 - 0.00072 19.3 7.7 0.78 9.5 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 KXX77453.1 - 3.9e-13 49.2 2.4 1.7e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Centromere-associated protein K Atg14 PF10186.4 KXX77453.1 - 0.2 10.5 12.0 0.011 14.7 3.9 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IF-2B PF01008.12 KXX77453.1 - 0.56 9.1 3.0 1 8.2 2.1 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family cwf21 PF08312.7 KXX77453.1 - 1.2 9.0 10.6 10 6.0 0.1 3.3 3 0 0 3 3 3 0 cwf21 domain Bap31 PF05529.7 KXX77453.1 - 9 5.7 10.6 0.5 9.7 3.0 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like dUTPase PF00692.14 KXX77454.1 - 5e-45 152.1 0.0 6e-45 151.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase DUF1765 PF08578.5 KXX77455.1 - 3.6e-49 166.0 1.1 5.8e-49 165.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SBF PF01758.11 KXX77456.1 - 6.4e-48 162.6 11.6 6.4e-48 162.6 8.0 1.9 1 1 0 1 1 1 1 Sodium Bile acid symporter family DUF2061 PF09834.4 KXX77456.1 - 1.5 9.0 9.1 0.97 9.6 0.2 4.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2061) CHASE3 PF05227.8 KXX77457.1 - 0.014 15.0 0.6 0.03 13.9 0.4 1.5 1 0 0 1 1 1 0 CHASE3 domain YlbD_coat PF14071.1 KXX77457.1 - 0.023 14.7 1.0 0.051 13.6 0.7 1.5 1 0 0 1 1 1 0 Putative coat protein Baculo_PEP_C PF04513.7 KXX77457.1 - 0.12 12.1 4.0 1.7 8.4 0.7 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.1 KXX77457.1 - 0.16 11.7 0.2 0.16 11.7 0.2 1.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate Tir_receptor_M PF03549.9 KXX77457.1 - 0.44 10.7 3.7 6.8 6.9 0.1 2.7 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain Peptidase_C12 PF01088.16 KXX77458.1 - 8.4e-54 181.9 0.0 1e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PCNA_N PF00705.13 KXX77459.1 - 2.3e-56 188.7 4.6 5.4e-56 187.5 2.6 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KXX77459.1 - 9.8e-52 174.2 0.2 3.1e-51 172.5 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KXX77459.1 - 4.9e-10 38.9 0.1 5.9e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KXX77459.1 - 2.1e-07 29.9 1.3 1.2e-05 24.2 0.9 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 KXX77459.1 - 9.3e-06 24.7 0.2 0.0038 16.2 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein FliW PF02623.10 KXX77459.1 - 0.12 11.9 0.1 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 FliW protein IL12p40_C PF10420.4 KXX77459.1 - 0.13 12.3 0.0 0.61 10.2 0.0 2.1 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus KAR9 PF08580.5 KXX77461.1 - 6.4e-147 490.7 2.0 6.4e-147 490.7 1.4 2.0 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DUF4618 PF15397.1 KXX77461.1 - 0.035 13.4 1.2 0.14 11.5 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3829 PF12889.2 KXX77461.1 - 0.25 10.5 2.5 19 4.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) Syntaxin-6_N PF09177.6 KXX77461.1 - 0.38 11.1 9.9 2.9 8.3 0.2 4.1 3 2 0 3 3 3 0 Syntaxin 6, N-terminal Ank_2 PF12796.2 KXX77462.1 - 1.3e-51 172.8 1.3 3.4e-16 59.3 0.0 9.4 4 2 4 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77462.1 - 2.4e-36 121.7 13.2 3.1e-06 26.6 0.0 13.5 14 0 0 14 14 14 5 Ankyrin repeat Ank_3 PF13606.1 KXX77462.1 - 2.7e-36 119.9 6.7 2.8e-05 23.9 0.0 14.4 17 0 0 17 17 17 7 Ankyrin repeat Ank_4 PF13637.1 KXX77462.1 - 3.5e-31 106.9 7.6 1.8e-05 25.0 0.0 11.7 10 2 2 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77462.1 - 1.8e-26 91.5 19.3 0.0005 20.2 0.3 11.9 12 2 1 14 14 14 6 Ankyrin repeats (many copies) DUF1282 PF06930.7 KXX77463.1 - 0.00076 19.1 0.2 0.00077 19.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) AA_permease_2 PF13520.1 KXX77463.1 - 0.004 15.7 0.2 0.0048 15.4 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.12 KXX77463.1 - 0.013 14.9 0.5 0.015 14.8 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4013 PF13197.1 KXX77463.1 - 0.019 14.2 0.3 0.023 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF4064 PF13273.1 KXX77463.1 - 0.24 11.4 3.2 1.3 9.1 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Brix PF04427.13 KXX77464.1 - 9.3e-32 110.2 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain MFS_1 PF07690.11 KXX77465.1 - 9.8e-27 93.5 21.0 1.3e-26 93.1 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 KXX77466.1 - 3.3e-44 150.6 12.6 3.9e-44 150.3 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Helicase_C PF00271.26 KXX77467.1 - 1.3e-19 69.8 0.1 1.6e-17 63.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX77467.1 - 5.3e-19 68.3 0.0 2.3e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 KXX77467.1 - 9.1e-07 28.5 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 KXX77467.1 - 0.0098 15.5 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 KXX77467.1 - 0.038 13.8 1.9 1 9.1 0.0 3.6 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit DUF2837 PF10997.3 KXX77467.1 - 0.29 10.2 0.0 0.5 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2837) Phos_pyr_kin PF08543.7 KXX77468.1 - 2.3e-11 43.3 0.0 4.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KXX77468.1 - 2.5e-08 33.4 0.1 2.2e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Lzipper-MIP1 PF14389.1 KXX77469.1 - 0.0043 17.1 0.8 0.012 15.6 0.2 2.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 KXX77469.1 - 0.16 11.4 2.5 0.39 10.2 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator Mito_carr PF00153.22 KXX77470.1 - 4.9e-67 221.6 0.3 3e-21 74.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.4 KXX77471.1 - 1.4e-51 174.3 3.5 2.3e-51 173.6 0.1 2.4 3 0 0 3 3 3 1 Apolipoprotein O CAP_GLY PF01302.20 KXX77472.1 - 5.9e-17 61.1 0.2 1.6e-16 59.7 0.2 1.8 1 0 0 1 1 1 1 CAP-Gly domain AAA_13 PF13166.1 KXX77472.1 - 0.00092 17.8 7.7 0.00092 17.8 5.4 2.0 1 1 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 KXX77472.1 - 0.012 15.8 6.5 0.085 13.1 1.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KXX77472.1 - 0.023 12.0 19.5 0.039 11.2 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med4 PF10018.4 KXX77472.1 - 0.031 13.6 20.9 0.042 13.2 1.5 3.2 3 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Reo_sigmaC PF04582.7 KXX77472.1 - 0.077 12.1 2.3 4.8 6.2 0.5 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KXX77472.1 - 0.11 11.1 22.9 0.28 9.7 5.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Nsp1_C PF05064.8 KXX77472.1 - 0.23 11.0 8.7 4.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Nsp1-like C-terminal region Pkip-1 PF06878.6 KXX77472.1 - 0.31 10.8 7.1 3.5 7.5 0.2 2.3 1 1 1 2 2 2 0 Pkip-1 protein Phage_GP20 PF06810.6 KXX77472.1 - 0.41 10.0 16.0 0.09 12.2 2.1 3.2 4 0 0 4 4 4 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KXX77472.1 - 0.53 10.0 4.6 0.84 9.4 1.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 KXX77472.1 - 1.5 9.1 15.8 0.1 12.9 1.9 3.8 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term BLOC1_2 PF10046.4 KXX77472.1 - 2 8.6 17.2 0.06 13.4 3.5 3.5 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.18 KXX77472.1 - 2.3 6.9 7.7 6.1 5.6 0.2 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain Cauli_AT PF03233.8 KXX77472.1 - 3 7.5 4.4 1.4 8.5 1.0 2.0 2 0 0 2 2 2 0 Aphid transmission protein Glutaredoxin2_C PF04399.8 KXX77472.1 - 3.1 7.3 6.3 8.9 5.9 0.9 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain TPR_MLP1_2 PF07926.7 KXX77472.1 - 3.9 7.2 26.5 0.13 11.9 9.0 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Mod_r PF07200.8 KXX77472.1 - 4.4 7.2 15.2 0.24 11.2 3.3 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.8 KXX77472.1 - 5.4 6.3 5.5 1.8 7.9 1.1 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1660 PF07874.6 KXX77473.1 - 0.098 12.9 0.7 5.8 7.2 0.0 2.9 2 1 0 2 2 2 0 Prophage protein (DUF1660) IU_nuc_hydro PF01156.14 KXX77474.1 - 3.1e-78 263.1 0.0 3.6e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pkinase PF00069.20 KXX77475.1 - 6.8e-35 120.4 0.0 1e-20 73.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77475.1 - 1.6e-11 43.7 0.0 5.3e-10 38.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX77475.1 - 1.7e-07 31.2 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX77475.1 - 0.0032 16.4 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like IMS PF00817.15 KXX77476.1 - 5.6e-41 139.7 0.0 1.2e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KXX77476.1 - 2.2e-17 63.1 0.0 5.6e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KXX77476.1 - 1.6e-12 47.2 13.1 3.9e-07 29.9 1.9 3.8 2 2 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KXX77476.1 - 0.00015 21.6 1.3 0.00049 19.9 0.1 2.5 2 0 0 2 2 2 1 IMS family HHH motif MgtE_N PF03448.12 KXX77476.1 - 0.0012 19.0 0.1 12 6.3 0.0 4.2 4 0 0 4 4 4 1 MgtE intracellular N domain HHH_5 PF14520.1 KXX77476.1 - 0.011 15.9 0.1 0.048 13.8 0.1 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain BRCT PF00533.21 KXX77476.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 KXX77476.1 - 0.089 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FliG_M PF14841.1 KXX77476.1 - 0.089 12.8 0.7 44 4.1 0.0 3.8 4 0 0 4 4 4 0 FliG middle domain RED_N PF07808.8 KXX77477.1 - 1.1e-09 37.9 11.3 1.1e-09 37.9 7.9 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region Peptidase_M3 PF01432.15 KXX77478.1 - 5.4e-118 394.9 0.0 9.7e-118 394.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KXX77478.1 - 0.018 14.4 0.2 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like HEAT_2 PF13646.1 KXX77478.1 - 0.3 11.3 3.1 18 5.7 0.3 2.9 2 1 0 2 2 2 0 HEAT repeats WSC PF01822.14 KXX77479.1 - 3.3e-16 58.9 9.0 5.5e-16 58.2 6.2 1.4 1 0 0 1 1 1 1 WSC domain DUF202 PF02656.10 KXX77480.1 - 1.2e-25 89.4 2.1 1.2e-25 89.4 1.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Sod_Fe_C PF02777.13 KXX77481.1 - 3.7e-09 36.3 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Ank PF00023.25 KXX77483.1 - 2.6e-58 191.0 11.5 3.1e-09 36.1 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KXX77483.1 - 3.4e-54 181.1 2.0 6.5e-22 77.6 0.4 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX77483.1 - 5.3e-46 154.2 19.9 2.2e-12 47.1 0.1 8.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77483.1 - 1.1e-34 114.9 4.6 9.3e-05 22.3 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KXX77483.1 - 9.6e-32 108.2 10.7 9.6e-11 41.5 0.4 6.2 3 2 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 KXX77483.1 - 2.9e-08 33.5 0.1 7.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX77483.1 - 7.7e-07 29.3 0.0 2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77483.1 - 3.1e-05 24.0 0.3 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KXX77483.1 - 0.005 17.0 0.0 0.02 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.2 KXX77483.1 - 0.02 14.7 5.6 0.49 10.2 0.0 4.1 3 1 0 4 4 4 0 Alpha/beta hydrolase family KAP_NTPase PF07693.9 KXX77483.1 - 0.021 13.8 2.7 0.5 9.3 0.1 2.7 2 1 0 3 3 3 0 KAP family P-loop domain AAA_17 PF13207.1 KXX77483.1 - 0.026 15.3 0.3 0.11 13.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX77483.1 - 0.031 14.1 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX77483.1 - 0.034 14.4 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 KXX77483.1 - 0.04 14.0 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase SHR3_chaperone PF08229.6 KXX77484.1 - 2.9e-65 218.9 0.0 3.5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4131 PF13567.1 KXX77484.1 - 0.0076 15.6 0.9 0.17 11.3 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Ni_hydr_CYTB PF01292.15 KXX77484.1 - 0.016 14.6 0.4 0.043 13.2 0.1 1.8 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KXX77484.1 - 0.047 13.0 1.4 0.15 11.3 0.1 2.3 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Fungal_trans_2 PF11951.3 KXX77485.1 - 9.9e-79 264.6 0.0 1.2e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77485.1 - 1.7e-07 31.0 5.2 2.9e-07 30.2 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_38 PF01074.17 KXX77486.1 - 1.8e-91 306.2 0.5 4.5e-91 304.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KXX77486.1 - 2.4e-74 250.7 0.0 6.6e-74 249.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KXX77486.1 - 4.1e-26 91.0 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain AAA_11 PF13086.1 KXX77487.1 - 3.9e-58 196.8 0.1 1e-57 195.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KXX77487.1 - 1.4e-55 187.7 0.0 3.9e-55 186.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX77487.1 - 6.4e-12 45.0 2.4 9.5e-12 44.5 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 KXX77487.1 - 1.3e-09 37.9 0.0 5.7e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KXX77487.1 - 5.6e-07 29.5 0.0 1.5e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KXX77487.1 - 1.2e-06 27.8 0.1 8e-06 25.0 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KXX77487.1 - 1.6e-06 27.7 0.0 0.61 9.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KXX77487.1 - 2.7e-05 23.6 0.0 0.00012 21.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KXX77487.1 - 0.00021 21.4 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX77487.1 - 0.0023 17.3 0.1 0.027 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 KXX77487.1 - 0.0024 17.4 0.0 0.018 14.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KXX77487.1 - 0.0025 17.0 0.0 0.057 12.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KXX77487.1 - 0.0026 16.7 0.0 0.0049 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KXX77487.1 - 0.003 17.3 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain Zot PF05707.7 KXX77487.1 - 0.0041 16.6 0.0 0.053 12.9 0.0 2.6 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KXX77487.1 - 0.0043 16.5 0.0 0.04 13.3 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA PF00004.24 KXX77487.1 - 0.0044 17.2 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX77487.1 - 0.0045 16.9 0.8 0.011 15.7 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain UvrD_C PF13361.1 KXX77487.1 - 0.0063 16.0 0.1 3.8 6.8 0.0 3.0 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 KXX77487.1 - 0.01 16.6 1.3 0.56 11.0 0.5 3.0 2 1 0 2 2 2 0 AAA domain 4HB_MCP_1 PF12729.2 KXX77487.1 - 0.016 14.5 0.1 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_33 PF13671.1 KXX77487.1 - 0.02 14.7 0.0 0.33 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KXX77487.1 - 0.025 14.3 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KXX77487.1 - 0.029 13.8 0.0 0.072 12.5 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KXX77487.1 - 0.034 12.7 0.0 0.058 12.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.1 KXX77487.1 - 0.071 13.2 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SAM_2 PF07647.12 KXX77488.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX77488.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KXX77488.1 - 0.0044 17.2 0.0 0.056 13.6 0.0 2.6 1 1 0 1 1 1 1 PH domain Aldo_ket_red PF00248.16 KXX77489.1 - 4.7e-51 173.2 0.0 6.2e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 KXX77489.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF530 PF04409.7 KXX77489.1 - 0.14 10.2 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) FAM163 PF15069.1 KXX77490.1 - 0.029 14.9 0.1 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 FAM163 family TMEM154 PF15102.1 KXX77490.1 - 0.048 13.3 0.2 0.077 12.6 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Myco_19_kDa PF05481.7 KXX77490.1 - 0.17 11.6 3.6 0.35 10.6 2.5 1.4 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Nop14 PF04147.7 KXX77491.1 - 4.8e-272 904.7 26.2 5.7e-272 904.5 18.1 1.0 1 0 0 1 1 1 1 Nop14-like family RVT_2 PF07727.9 KXX77492.1 - 1.7e-55 187.6 0.0 2.6e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KXX77492.1 - 0.058 12.7 0.2 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 KXX77493.1 - 0.00085 18.9 0.7 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 KXX77493.1 - 0.013 15.2 0.1 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FYVE PF01363.16 KXX77493.1 - 0.022 14.6 1.6 0.022 14.6 1.1 1.7 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 KXX77493.1 - 0.034 13.9 3.6 0.099 12.4 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KXX77493.1 - 0.63 9.3 4.6 0.95 8.7 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ketoacyl-synt PF00109.21 KXX77494.1 - 5.4e-79 265.2 0.0 9.5e-79 264.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KXX77494.1 - 1.3e-62 211.5 0.1 6.1e-62 209.3 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 KXX77494.1 - 2.2e-53 180.6 0.0 1.2e-51 174.9 0.0 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KXX77494.1 - 3.1e-48 164.7 0.2 6.1e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX77494.1 - 1.6e-47 162.1 0.0 3e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX77494.1 - 2.3e-45 154.5 0.0 2.3e-42 144.7 0.0 3.1 2 0 0 2 2 2 1 short chain dehydrogenase Condensation PF00668.15 KXX77494.1 - 2.2e-44 151.5 0.3 3.9e-44 150.7 0.2 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KXX77494.1 - 1.2e-30 106.2 0.0 2.8e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KXX77494.1 - 1.8e-28 98.7 0.0 3.9e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX77494.1 - 1.5e-16 60.7 0.0 8.4e-16 58.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KXX77494.1 - 4.3e-12 46.1 3.3 3e-05 24.1 0.1 3.7 4 0 0 4 4 3 2 Phosphopantetheine attachment site Epimerase PF01370.16 KXX77494.1 - 3.3e-11 43.0 0.0 5.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KXX77494.1 - 1e-09 38.7 0.0 4.2e-09 36.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KXX77494.1 - 4.2e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KXX77494.1 - 4.8e-08 33.2 0.0 6.8e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_23 PF13489.1 KXX77494.1 - 6.7e-08 32.4 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77494.1 - 8.6e-06 26.3 0.0 4.5e-05 23.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77494.1 - 1.2e-05 24.9 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KXX77494.1 - 7.1e-05 21.9 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KXX77494.1 - 0.00074 18.3 0.0 0.063 11.9 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KXX77494.1 - 0.0052 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NmrA PF05368.8 KXX77494.1 - 0.03 13.5 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family Rhabdo_ncap PF00945.13 KXX77494.1 - 0.32 9.5 0.0 0.55 8.7 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF1681 PF07933.9 KXX77494.1 - 0.33 10.4 0.0 9.8 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Zn_clus PF00172.13 KXX77496.1 - 2.9e-06 27.0 6.7 5.4e-06 26.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLAC1 PF03595.12 KXX77499.1 - 1.1e-68 231.3 44.8 1.3e-68 231.1 31.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CorA PF01544.13 KXX77500.1 - 6.7e-09 35.1 0.2 6.7e-09 35.1 0.1 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ammonium_transp PF00909.16 KXX77500.1 - 0.036 12.5 1.6 0.047 12.1 1.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family DUF3429 PF11911.3 KXX77501.1 - 5.5e-40 136.6 9.6 7.3e-40 136.2 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.5 KXX77501.1 - 0.035 13.8 4.6 0.071 12.9 3.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Transgly_assoc PF04226.8 KXX77501.1 - 0.064 13.3 2.0 0.38 10.8 0.2 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4220 PF13968.1 KXX77501.1 - 0.19 10.7 0.3 0.27 10.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4337 PF14235.1 KXX77501.1 - 8.7 6.1 13.7 17 5.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FAD_binding_3 PF01494.14 KXX77502.1 - 4e-16 59.0 0.0 1e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX77502.1 - 3.2e-08 32.8 0.0 0.00042 19.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX77502.1 - 2.9e-05 24.3 0.0 0.013 15.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX77502.1 - 0.0014 17.3 0.0 0.25 9.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KXX77502.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 KXX77502.1 - 0.23 10.2 0.0 1.7 7.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DUF1162 PF06650.7 KXX77503.1 - 2.8e-75 253.1 0.0 4.9e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 KXX77503.1 - 3.3e-06 27.1 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 ATG C terminal domain Amidase PF01425.16 KXX77504.1 - 4.7e-87 292.6 0.0 5.8e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Ank_2 PF12796.2 KXX77505.1 - 1.4e-52 175.9 0.2 2.5e-15 56.5 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77505.1 - 1.8e-44 147.3 3.5 6.3e-08 32.0 0.0 9.6 9 1 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 KXX77505.1 - 4.5e-29 97.5 0.6 0.0013 18.7 0.0 9.2 8 1 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KXX77505.1 - 3e-27 94.4 0.4 4.8e-09 36.4 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77505.1 - 5.9e-24 83.5 8.1 0.00011 22.3 0.1 7.5 4 4 5 9 9 9 7 Ankyrin repeats (many copies) WhiA_N PF10298.4 KXX77505.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain WSC PF01822.14 KXX77507.1 - 3.7e-08 33.1 0.2 4.9e-08 32.7 0.2 1.1 1 0 0 1 1 1 1 WSC domain p450 PF00067.17 KXX77508.1 - 4e-48 164.0 0.0 4.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX77509.1 - 2.6e-12 45.9 0.0 3.4e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chorein_N PF12624.2 KXX77510.1 - 1.2e-41 140.9 0.1 3.4e-41 139.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KXX77510.1 - 1.1e-06 28.1 0.0 0.0001 21.6 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) HLH PF00010.21 KXX77513.1 - 2.5e-09 36.7 0.0 4.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA PF00004.24 KXX77514.1 - 1.7e-11 44.4 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX77514.1 - 9e-06 25.8 0.1 3.3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KXX77514.1 - 4.7e-05 22.5 0.0 8.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX77514.1 - 0.00037 20.2 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KXX77514.1 - 0.00044 20.1 2.0 0.00053 19.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KXX77514.1 - 0.00083 19.0 0.0 0.0029 17.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KXX77514.1 - 0.0032 16.2 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KXX77514.1 - 0.0047 17.7 0.0 0.018 15.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 KXX77514.1 - 0.0057 15.5 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 KXX77514.1 - 0.0068 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KXX77514.1 - 0.0074 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77514.1 - 0.0076 16.2 1.0 0.097 12.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KXX77514.1 - 0.036 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KXX77514.1 - 0.037 13.1 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Ribosomal_60s PF00428.14 KXX77514.1 - 1 9.7 13.7 2.8 8.4 0.4 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein RPAP2_Rtr1 PF04181.8 KXX77515.1 - 1e-17 63.9 3.4 1.8e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family SR-25 PF10500.4 KXX77515.1 - 0.0069 15.8 4.8 0.0069 15.8 3.3 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3292 PF11696.3 KXX77515.1 - 0.22 9.3 9.3 0.33 8.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) bZIP_C PF12498.3 KXX77515.1 - 2.3 9.4 17.8 6.3 8.0 12.4 1.8 1 0 0 1 1 1 0 Basic leucine-zipper C terminal FimP PF09766.4 KXX77515.1 - 2.7 6.9 19.2 4.9 6.1 13.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein U3_snoRNA_assoc PF08297.6 KXX77515.1 - 4 7.7 18.8 3.3 8.0 0.1 3.1 2 1 0 2 2 2 0 U3 snoRNA associated Band_3_cyto PF07565.8 KXX77515.1 - 5.7 6.3 11.4 3 7.3 6.3 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dala_Dala_lig_N PF01820.16 KXX77515.1 - 8.8 6.6 9.9 35 4.7 0.0 2.8 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Neur_chan_memb PF02932.11 KXX77515.1 - 8.9 6.1 7.3 1.1 9.1 2.2 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SH3_1 PF00018.23 KXX77517.1 - 3.4e-12 45.5 0.2 1.4e-11 43.6 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KXX77517.1 - 1.7e-10 40.3 0.1 1.4e-09 37.3 0.2 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KXX77517.1 - 1.5e-08 33.9 0.0 6.6e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain eIF-3c_N PF05470.7 KXX77517.1 - 4.8 5.1 6.3 9.4 4.1 4.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ketoacyl-synt PF00109.21 KXX77518.1 - 1.3e-21 77.2 0.1 2.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KXX77518.1 - 3.3e-20 72.8 0.0 2.1e-19 70.2 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 KXX77518.1 - 7.6e-18 64.4 0.0 1.7e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KXX77518.1 - 7.8e-11 41.8 0.0 2.8e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KXX77518.1 - 5.9e-05 23.0 0.0 0.00022 21.1 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KXX77519.1 - 1.4e-81 274.3 0.0 3.9e-78 263.0 0.0 3.7 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KXX77519.1 - 2e-39 133.7 0.0 4.7e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KXX77519.1 - 3.4e-31 106.7 0.1 1.1e-30 105.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KXX77519.1 - 3.6e-24 85.0 0.2 1.9e-23 82.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Aminotran_5 PF00266.14 KXX77520.1 - 1.3e-31 109.6 0.0 1.6e-29 102.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Amidohydro_1 PF01979.15 KXX77521.1 - 1.8e-42 146.2 0.0 2.1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KXX77521.1 - 4.3e-06 26.4 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX77521.1 - 3e-05 23.4 10.1 0.00018 20.8 2.7 2.5 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KXX77521.1 - 0.0012 18.8 3.1 0.0085 16.1 2.2 2.2 1 1 0 1 1 1 1 Amidohydrolase NMD3 PF04981.8 KXX77522.1 - 0.0099 15.0 0.3 0.015 14.4 0.2 1.4 1 0 0 1 1 1 1 NMD3 family Rsa3 PF14615.1 KXX77522.1 - 0.021 14.1 0.0 0.061 12.6 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DUF2373 PF10180.4 KXX77522.1 - 0.033 13.7 0.1 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DZR PF12773.2 KXX77522.1 - 0.22 11.3 3.1 1.8 8.4 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KXX77522.1 - 0.32 10.5 1.7 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 DUF164 PF02591.10 KXX77522.1 - 0.39 10.5 2.2 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C3HC4_2 PF13923.1 KXX77522.1 - 1.1 9.3 3.7 2.2 8.4 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KXX77523.1 - 3.9e-55 184.1 24.6 2.2e-09 37.5 0.0 14.2 7 5 6 14 14 14 13 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77523.1 - 1.1e-26 91.2 32.3 0.00023 20.8 0.0 18.9 19 2 1 20 20 20 10 Ankyrin repeat Ank_3 PF13606.1 KXX77523.1 - 2.8e-22 76.5 10.9 0.0036 17.3 0.0 17.9 20 1 1 21 21 21 4 Ankyrin repeat Ank_4 PF13637.1 KXX77523.1 - 3.1e-17 62.5 13.3 0.0019 18.6 0.0 14.2 15 2 1 16 16 16 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77523.1 - 2.4e-13 49.8 19.1 0.00017 21.7 0.0 13.5 14 2 2 16 16 16 4 Ankyrin repeats (many copies) Sulfate_transp PF00916.15 KXX77524.1 - 3.2e-80 269.1 6.4 5.6e-80 268.3 4.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX77524.1 - 1.3e-29 101.6 4.6 1.3e-29 101.6 3.2 3.4 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KXX77524.1 - 1.4e-09 37.3 0.0 3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KXX77524.1 - 0.0017 18.3 0.2 0.0069 16.4 0.2 2.0 1 0 0 1 1 1 1 STAS domain MreB_Mbl PF06723.8 KXX77524.1 - 2 6.9 6.2 0.077 11.5 0.1 1.6 2 0 0 2 2 2 0 MreB/Mbl protein Abhydrolase_3 PF07859.8 KXX77525.1 - 6.4e-34 117.3 0.1 8.7e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX77525.1 - 0.0042 17.0 3.2 0.0058 16.5 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KXX77525.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PNP_UDP_1 PF01048.15 KXX77526.1 - 0.00011 21.3 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Helicase_C PF00271.26 KXX77527.1 - 3.3e-11 42.8 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Curlin_rpt PF07012.7 KXX77527.1 - 0.59 9.8 3.5 0.86 9.3 0.7 2.3 2 0 0 2 2 2 0 Curlin associated repeat COesterase PF00135.23 KXX77528.1 - 1.2e-83 281.6 0.0 1.5e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX77528.1 - 4.5e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX77528.1 - 0.019 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family FA_desaturase PF00487.19 KXX77529.1 - 3.3e-39 134.8 25.0 5e-39 134.3 17.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KXX77529.1 - 4.4e-11 42.4 0.0 9.6e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.2 KXX77529.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) adh_short PF00106.20 KXX77530.1 - 6.8e-06 26.1 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77530.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.1 KXX77531.1 - 4.3e-20 72.8 0.1 9e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX77531.1 - 5.3e-16 58.3 0.1 9.2e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 KXX77531.1 - 0.002 18.3 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.7 KXX77531.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 KXX77531.1 - 0.069 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 KXX77531.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 KXX77532.1 - 8.3e-20 70.7 0.3 1.3e-19 70.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77532.1 - 1.8e-09 37.3 7.7 3.9e-09 36.2 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 KXX77533.1 - 1.5e-100 336.9 1.0 1.8e-100 336.7 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S41 PF03572.13 KXX77534.1 - 1.8e-09 37.2 0.0 4.7e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 ketoacyl-synt PF00109.21 KXX77535.1 - 1.6e-66 224.4 3.9 6.9e-65 219.0 0.1 3.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX77535.1 - 1.3e-54 184.6 2.0 2.4e-54 183.7 0.1 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KXX77535.1 - 1.6e-52 178.8 0.1 2.6e-52 178.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX77535.1 - 5.4e-51 173.5 0.0 9.2e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX77535.1 - 1.5e-43 148.6 3.0 3.2e-42 144.2 0.1 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX77535.1 - 3e-40 136.7 0.1 6.9e-40 135.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX77535.1 - 3.8e-22 78.2 2.5 4.2e-20 71.6 0.0 4.2 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX77535.1 - 3e-18 66.9 0.0 4.2e-16 60.0 0.0 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KXX77535.1 - 8.7e-18 64.6 0.0 2.6e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX77535.1 - 6.5e-12 45.4 0.0 2e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77535.1 - 1.9e-09 37.8 0.0 7.8e-09 35.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77535.1 - 2.7e-07 29.9 0.0 5.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KXX77535.1 - 5e-07 30.2 0.0 5.8e-06 26.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77535.1 - 6.2e-06 26.5 0.1 0.00016 21.9 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 KXX77535.1 - 6.4e-06 26.3 0.1 1.6e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KXX77535.1 - 6.5e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 KXX77535.1 - 7e-05 21.9 0.1 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase Thiolase_N PF00108.18 KXX77535.1 - 0.00021 20.3 0.2 0.0007 18.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 KXX77535.1 - 0.0013 17.6 0.2 0.0054 15.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 KXX77535.1 - 0.0035 17.1 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX77535.1 - 0.0074 16.3 0.6 4.4 7.2 0.0 2.8 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KXX77535.1 - 0.0075 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KXX77535.1 - 0.015 14.0 0.1 0.027 13.1 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_9 PF08003.6 KXX77535.1 - 0.021 13.5 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 KXX77535.1 - 0.033 13.8 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase YflT PF11181.3 KXX77535.1 - 0.072 13.2 0.0 0.5 10.5 0.0 2.5 3 0 0 3 3 1 0 Heat induced stress protein YflT F420_oxidored PF03807.12 KXX77535.1 - 0.087 13.2 0.3 1.3 9.4 0.0 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NodS PF05401.6 KXX77535.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF3820 PF12843.2 KXX77535.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Methyltransf_16 PF10294.4 KXX77535.1 - 0.27 10.6 0.0 0.58 9.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Cupin_2 PF07883.6 KXX77536.1 - 8e-10 38.0 0.5 1.3e-09 37.4 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KXX77536.1 - 0.0056 16.1 0.1 0.007 15.8 0.1 1.3 1 1 0 1 1 1 1 Cupin Cupin_7 PF12973.2 KXX77536.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 ChrR Cupin-like domain zf-C2HC5 PF06221.8 KXX77537.1 - 4.9e-23 80.6 5.0 7.6e-23 80.0 3.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SIR2 PF02146.12 KXX77538.1 - 1.1e-29 103.3 0.0 3.9e-09 36.4 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Na_H_Exchanger PF00999.16 KXX77540.1 - 4e-31 107.9 35.1 3.4e-30 104.8 24.3 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Fst_toxin PF13955.1 KXX77540.1 - 0.027 14.1 1.5 0.027 14.1 1.0 4.2 4 0 0 4 4 4 0 Toxin Fst, type I toxin-antitoxin system Pro-kuma_activ PF09286.6 KXX77541.1 - 7.3e-31 107.1 0.0 1.2e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KXX77541.1 - 4.6e-09 35.8 0.0 6.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family p450 PF00067.17 KXX77542.1 - 7.2e-21 74.2 0.0 1e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX77543.1 - 2.4e-08 32.9 0.0 3.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 KXX77544.1 - 1.9e-16 60.0 3.3 2.6e-16 59.6 2.3 1.1 1 0 0 1 1 1 1 Subtilase family VWA_2 PF13519.1 KXX77546.1 - 3.7e-19 69.4 6.2 8.5e-19 68.2 4.3 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX77546.1 - 1e-14 54.6 0.3 2e-14 53.6 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KXX77546.1 - 7.3e-06 25.7 0.0 1.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KXX77546.1 - 0.00023 20.3 2.3 0.0046 16.1 1.6 2.1 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KXX77546.1 - 0.095 12.5 0.1 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 vWA found in TerF C terminus BTB PF00651.26 KXX77547.1 - 5.8e-07 29.4 0.0 9.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2360 PF10152.4 KXX77547.1 - 0.055 13.7 0.7 0.097 12.9 0.1 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Hemerythrin PF01814.18 KXX77548.1 - 0.51 10.4 3.4 3.7 7.7 0.1 3.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain Globin PF00042.17 KXX77550.1 - 7.2e-10 39.2 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 KXX77550.1 - 4.9e-08 32.9 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KXX77550.1 - 3.4e-07 30.8 0.0 7.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 KXX77550.1 - 0.0013 18.3 0.1 0.0033 17.0 0.0 1.7 2 0 0 2 2 2 1 Protoglobin NAD_binding_6 PF08030.7 KXX77550.1 - 0.0022 17.8 0.1 0.052 13.4 0.0 2.6 3 0 0 3 3 3 1 Ferric reductase NAD binding domain APH PF01636.18 KXX77551.1 - 4.4e-06 26.6 0.2 3.6e-05 23.6 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX77551.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 KXX77553.1 - 1.4e-24 86.8 6.9 1.9e-24 86.4 4.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX77553.1 - 6.9e-24 84.9 0.1 8.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX77553.1 - 1.7e-12 47.3 3.9 2.5e-12 46.8 2.7 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KXX77555.1 - 7.9e-10 38.0 0.0 1.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77555.1 - 1.3e-06 28.2 9.3 1.3e-06 28.2 6.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain He_PIG PF05345.7 KXX77555.1 - 0.26 11.3 3.9 0.65 10.0 2.7 1.6 1 0 0 1 1 1 0 Putative Ig domain p450 PF00067.17 KXX77556.1 - 1.3e-24 86.5 0.0 1.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1014 PF06244.7 KXX77557.1 - 2.6e-09 37.3 0.4 3.1e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) SurA_N PF09312.6 KXX77557.1 - 0.13 12.0 0.3 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DEAD PF00270.24 KXX77558.1 - 1.5e-19 70.1 0.0 4.7e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX77558.1 - 8.1e-07 28.8 0.0 2.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KXX77558.1 - 0.00011 22.3 0.0 0.00036 20.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 KXX77558.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KXX77558.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain zf-HC5HC2H_2 PF13832.1 KXX77559.1 - 7.6e-21 74.1 1.8 7.6e-21 74.1 1.3 4.1 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KXX77559.1 - 4.8e-18 65.0 3.3 4.8e-18 65.0 2.3 4.8 5 0 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.13 KXX77559.1 - 1.7e-16 60.0 0.0 4.3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KXX77559.1 - 1.5e-09 37.4 24.4 2.6e-06 27.0 7.2 6.7 8 0 0 8 8 8 3 PHD-finger PHD_2 PF13831.1 KXX77559.1 - 6.1e-09 35.0 3.0 6.1e-09 35.0 2.1 5.9 7 0 0 7 7 7 2 PHD-finger Myb_DNA-binding PF00249.26 KXX77559.1 - 0.0018 18.2 0.1 0.0059 16.6 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.17 KXX77559.1 - 0.0029 17.2 1.5 0.0029 17.2 1.0 5.9 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KXX77559.1 - 0.58 9.9 48.0 0.08 12.6 1.2 4.5 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Ribonuc_L-PSP PF01042.16 KXX77561.1 - 2.7e-10 40.0 0.0 4.1e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP PWWP PF00855.12 KXX77562.1 - 0.081 13.1 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 PWWP domain Tox-HNH-EHHH PF15657.1 KXX77562.1 - 1.2 9.3 6.1 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins MMR_HSR1 PF01926.18 KXX77563.1 - 1.4e-17 63.6 0.2 2.8e-15 56.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX77563.1 - 3.9e-07 29.4 0.2 2.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KXX77563.1 - 0.0004 19.6 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KXX77563.1 - 0.0012 18.6 0.1 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KXX77563.1 - 0.031 14.7 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 KXX77563.1 - 0.043 12.9 0.1 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 KXX77563.1 - 0.045 13.1 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 KXX77563.1 - 0.12 11.7 0.3 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L5_C PF00673.16 KXX77564.1 - 7.7e-22 76.8 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KXX77564.1 - 0.0032 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.5 KXX77565.1 - 1.9e-35 121.2 2.6 1.9e-35 121.2 1.8 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KXX77565.1 - 3.9e-11 43.0 2.3 1.6e-05 25.1 0.1 2.1 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 KXX77565.1 - 5e-07 29.3 0.1 0.0032 17.2 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KXX77565.1 - 6.3e-05 23.3 0.7 0.0018 18.7 0.0 2.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 KXX77565.1 - 0.0021 17.9 0.1 0.046 13.8 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat Aconitase_B_N PF11791.3 KXX77565.1 - 0.02 14.7 0.0 0.35 10.6 0.0 2.7 2 1 1 3 3 3 0 Aconitate B N-terminal domain Actin PF00022.14 KXX77566.1 - 5.5e-159 528.7 0.0 6.3e-159 528.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KXX77566.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3317 PF11779.3 KXX77567.1 - 9.8e-19 66.5 7.1 1.3e-18 66.2 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) WD40 PF00400.27 KXX77568.1 - 3.5e-62 204.2 11.2 6.2e-08 32.2 0.0 12.1 13 0 0 13 13 13 10 WD domain, G-beta repeat Urm1 PF09138.6 KXX77569.1 - 3.8e-34 116.6 0.0 4.3e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KXX77569.1 - 0.053 13.9 0.0 0.063 13.7 0.0 1.2 1 0 0 1 1 1 0 ThiS family RF-1 PF00472.15 KXX77570.1 - 3.4e-26 91.2 1.6 6.1e-26 90.4 1.1 1.3 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.17 KXX77571.1 - 5.7e-34 115.5 0.0 5.5e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77571.1 - 2.4e-17 62.6 0.0 1e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77571.1 - 8.8e-16 57.5 0.0 8.7e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KXX77571.1 - 0.0031 16.9 0.1 3.4 7.2 0.1 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 KXX77571.1 - 0.0041 16.8 0.1 0.68 9.7 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 Tom7 PF08038.7 KXX77572.1 - 4.7e-19 67.5 0.3 7.8e-19 66.8 0.2 1.4 1 0 0 1 1 1 1 TOM7 family Aminotran_1_2 PF00155.16 KXX77573.1 - 7.2e-11 41.6 0.0 1.2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II LTV PF04180.9 KXX77574.1 - 5.9e-115 385.1 6.1 6.6e-115 384.9 4.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein Mito_carr PF00153.22 KXX77575.1 - 2.3e-57 190.7 1.1 5.6e-20 70.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 KXX77576.1 - 2.9e-19 68.1 23.2 1.2e-06 28.4 0.3 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX77576.1 - 5.3e-17 60.8 20.3 6.6e-05 22.9 0.1 4.7 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX77576.1 - 3.1e-14 52.4 31.4 1.9e-07 31.0 0.5 5.0 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 KXX77576.1 - 0.016 15.0 0.3 0.016 15.0 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 KXX77576.1 - 0.023 14.6 4.0 4.4 7.3 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain GATA PF00320.22 KXX77576.1 - 0.034 13.5 1.8 6.2 6.2 0.2 2.9 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_jaz PF12171.3 KXX77576.1 - 1.2 9.4 14.0 1.8 8.7 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX77576.1 - 2.9 8.2 9.2 3 8.1 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KXX77576.1 - 3.4 8.1 13.2 4 7.8 0.9 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 KXX77576.1 - 5 6.9 16.2 1 9.1 1.0 3.5 1 1 3 4 4 4 0 BED zinc finger zf-C2H2_2 PF12756.2 KXX77576.1 - 8.3 6.5 10.9 1.6 8.9 0.4 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) MIF4G_like PF09088.6 KXX77577.1 - 5.6e-87 290.1 0.1 8.6e-87 289.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KXX77577.1 - 1.5e-55 188.2 0.0 2.3e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KXX77577.1 - 0.071 12.5 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain FMO-like PF00743.14 KXX77578.1 - 3.5e-46 157.5 0.0 1.2e-25 89.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KXX77578.1 - 3.1e-18 66.5 0.1 1.2e-16 61.4 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX77578.1 - 3.3e-15 56.1 0.1 5.5e-14 52.2 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX77578.1 - 7e-11 42.3 0.0 1.6e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX77578.1 - 1.2e-09 37.6 0.6 8.4e-08 31.5 0.0 2.8 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KXX77578.1 - 1.7e-07 31.1 0.0 7.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX77578.1 - 1.3e-06 27.6 0.1 4.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KXX77578.1 - 1.8e-06 27.1 0.1 0.011 14.7 0.0 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX77578.1 - 0.0014 17.2 1.1 0.023 13.2 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 KXX77578.1 - 0.002 18.5 0.4 0.49 10.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KXX77578.1 - 0.0051 15.9 0.2 0.53 9.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KXX77578.1 - 0.063 12.1 0.1 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KXX77578.1 - 0.13 12.3 0.1 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KXX77578.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Malic_M PF03949.10 KXX77580.1 - 4.7e-87 291.7 0.0 7.4e-87 291.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KXX77580.1 - 1.5e-71 239.7 0.0 3.2e-71 238.6 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2217 PF10265.4 KXX77580.1 - 2.2 6.9 5.5 68 2.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) LRR_8 PF13855.1 KXX77581.1 - 2.6e-05 23.8 1.1 1.1 9.0 0.0 5.0 5 1 0 5 5 5 2 Leucine rich repeat GATA PF00320.22 KXX77581.1 - 4.4e-05 22.7 2.5 0.00072 18.8 0.5 2.5 2 0 0 2 2 2 1 GATA zinc finger LRR_6 PF13516.1 KXX77581.1 - 5.1e-05 22.9 1.9 0.52 10.5 0.0 6.2 8 0 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 KXX77581.1 - 0.0025 17.7 8.2 58 4.5 0.0 6.8 8 1 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 KXX77581.1 - 0.0057 16.5 1.0 41 4.7 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.2 KXX77581.1 - 0.0066 16.0 0.5 31 4.3 0.0 4.8 3 1 3 6 6 5 0 Leucine Rich repeats (2 copies) Herpes_DNAp_acc PF04929.7 KXX77581.1 - 9.4 5.0 5.9 15 4.4 4.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SNF2_N PF00176.18 KXX77582.1 - 2.6e-62 210.3 0.0 4.1e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX77582.1 - 1.4e-12 47.3 0.0 4e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KXX77582.1 - 4e-08 32.7 9.4 4e-08 32.7 6.5 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KXX77582.1 - 1.3e-07 31.6 0.0 3.8e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KXX77582.1 - 7.9e-06 25.4 0.0 2.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KXX77582.1 - 1.5e-05 24.6 8.7 1.5e-05 24.6 6.0 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX77582.1 - 2.6e-05 24.1 8.6 2.6e-05 24.1 5.9 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX77582.1 - 0.00019 21.0 7.6 0.00019 21.0 5.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX77582.1 - 0.0065 16.1 8.9 0.0065 16.1 6.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KXX77582.1 - 0.029 14.1 3.1 0.074 12.8 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AAA_34 PF13872.1 KXX77582.1 - 0.031 13.0 0.0 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.3 KXX77582.1 - 0.27 10.7 6.7 0.24 10.9 2.8 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF1793 PF08760.6 KXX77583.1 - 1.3e-79 265.9 0.2 6.8e-79 263.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 KXX77584.1 - 2.5e-19 68.6 0.0 3.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77584.1 - 3.3e-16 59.0 0.0 5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77584.1 - 1.6e-09 37.4 0.0 2.4e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KXX77584.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain ABC_tran PF00005.22 KXX77585.1 - 1.2e-47 161.6 0.0 2.3e-26 92.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX77585.1 - 1.4e-38 132.9 32.6 8e-21 74.6 2.4 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_16 PF13191.1 KXX77585.1 - 7.3e-06 26.0 0.0 0.022 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 KXX77585.1 - 3e-05 24.5 1.1 0.11 13.0 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_21 PF13304.1 KXX77585.1 - 3.2e-05 24.0 1.2 1.6 8.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KXX77585.1 - 8.1e-05 22.5 0.5 0.2 11.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 KXX77585.1 - 8.5e-05 21.8 0.2 4.5 6.4 0.0 3.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX77585.1 - 9.5e-05 21.8 0.7 0.3 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KXX77585.1 - 0.00011 21.3 0.1 0.054 12.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 KXX77585.1 - 0.0002 20.5 0.9 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX77585.1 - 0.00052 20.3 0.8 0.45 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KXX77585.1 - 0.001 18.7 1.0 1.1 8.8 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX77585.1 - 0.001 18.5 0.1 0.2 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX77585.1 - 0.0014 19.4 3.0 0.49 11.2 0.5 2.9 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 KXX77585.1 - 0.0014 17.4 1.7 0.87 8.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KXX77585.1 - 0.0022 18.1 0.1 1.7 8.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KXX77585.1 - 0.0038 16.7 0.6 2.2 7.6 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 KXX77585.1 - 0.0094 15.6 1.1 1.5 8.5 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KXX77585.1 - 0.011 14.4 0.6 0.74 8.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KXX77585.1 - 0.013 14.9 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KXX77585.1 - 0.013 15.2 3.9 0.11 12.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 KXX77585.1 - 0.015 15.2 1.0 0.061 13.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KXX77585.1 - 0.019 14.6 0.4 0.43 10.2 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 KXX77585.1 - 0.036 14.3 1.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KXX77585.1 - 0.036 13.4 0.3 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KXX77585.1 - 0.095 12.4 1.0 0.33 10.7 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain ATP-synt_ab PF00006.20 KXX77585.1 - 0.1 12.1 0.3 8.3 5.8 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KXX77585.1 - 0.14 11.6 1.7 8.8 5.7 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 KXX77585.1 - 0.53 9.7 3.1 1.1 8.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KXX77585.1 - 0.55 10.0 7.0 0.6 9.9 0.1 3.0 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.1 KXX77585.1 - 0.57 9.1 0.0 9.7 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 KXX77586.1 - 2.6e-32 109.5 0.5 1.3e-12 47.0 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 KXX77586.1 - 6.1e-07 28.9 1.4 0.88 9.3 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KXX77586.1 - 8.9e-05 20.8 0.0 0.09 10.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KXX77586.1 - 0.0015 18.0 1.6 0.011 15.1 0.6 2.5 2 1 0 2 2 2 1 PQQ-like domain Proteasome_A_N PF10584.4 KXX77586.1 - 0.0017 17.6 0.1 22 4.4 0.0 3.4 3 0 0 3 3 3 3 Proteasome subunit A N-terminal signature DUF1652 PF07865.6 KXX77586.1 - 0.053 13.1 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Ost4 PF10215.4 KXX77587.1 - 1.2e-17 63.0 0.8 1.4e-17 62.8 0.5 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase Glutaredoxin PF00462.19 KXX77587.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin CS PF04969.11 KXX77588.1 - 3.1e-09 37.2 0.0 4.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.17 KXX77589.1 - 7.1e-16 57.6 0.0 1.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77589.1 - 4.6e-12 45.7 0.0 6.9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77589.1 - 4.1e-07 29.7 0.1 9.3e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KXX77589.1 - 1.6e-05 25.2 1.1 4.1e-05 23.9 0.7 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 KXX77589.1 - 0.037 14.0 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Ank_2 PF12796.2 KXX77590.1 - 2.2e-26 91.9 0.1 4.1e-12 46.2 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77590.1 - 7.6e-23 79.1 6.9 1.3e-05 24.7 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KXX77590.1 - 6.2e-17 61.2 3.2 5.1e-08 32.9 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77590.1 - 5.9e-16 56.9 6.3 0.0052 16.9 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KXX77590.1 - 9.1e-15 54.7 0.4 1.7e-06 28.3 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) adh_short PF00106.20 KXX77592.1 - 2.3e-16 60.1 0.1 3.5e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX77592.1 - 2.3e-07 30.8 0.0 2.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX77592.1 - 8e-07 28.8 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Pkinase PF00069.20 KXX77593.1 - 5.9e-71 238.6 0.0 1.1e-70 237.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77593.1 - 1.2e-30 106.4 0.0 2.3e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KXX77593.1 - 4e-06 26.0 0.0 0.33 9.8 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KXX77593.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX77593.1 - 0.064 12.9 0.0 1.5 8.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SLAC1 PF03595.12 KXX77594.1 - 8.9e-70 234.9 39.1 1.1e-69 234.5 27.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RNA_pol_Rpb4 PF03874.11 KXX77595.1 - 1.7e-24 86.0 0.4 2e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF3775 PF12616.3 KXX77595.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) MMS19_C PF12460.3 KXX77595.1 - 0.1 11.2 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DUF1539 PF07560.6 KXX77595.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Pribosyl_synth PF14572.1 KXX77596.1 - 2.4e-40 138.2 1.9 3.3e-35 121.5 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KXX77596.1 - 3.9e-30 103.9 0.0 7.1e-29 99.8 0.0 2.7 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KXX77596.1 - 7.7e-13 48.2 0.1 1.8e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KXX77596.1 - 0.0062 15.7 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PseudoU_synth_1 PF01416.15 KXX77597.1 - 2.6e-28 98.5 0.0 1.8e-21 76.5 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 KXX77598.1 - 1.2e-18 67.0 0.0 1.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX77598.1 - 8.8e-08 32.6 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX77598.1 - 0.00047 19.4 0.0 0.0041 16.3 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KXX77598.1 - 0.01 14.5 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF788 PF05620.6 KXX77599.1 - 3.3 7.5 3.3 7.7 6.3 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Snf7 PF03357.16 KXX77600.1 - 5.7e-19 68.1 13.7 5.7e-19 68.1 9.5 2.1 1 1 1 2 2 2 1 Snf7 CsbD PF05532.7 KXX77600.1 - 0.079 12.6 1.0 1.7 8.3 0.4 2.6 2 0 0 2 2 2 0 CsbD-like DUF4611 PF15387.1 KXX77600.1 - 1 9.5 11.5 1.7 8.8 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) TMEM247 PF15444.1 KXX77601.1 - 0.063 13.0 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Glyco_hydro_62 PF03664.8 KXX77601.1 - 0.09 11.8 2.3 0.1 11.6 1.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 62 Herpes_DNAp_acc PF04929.7 KXX77601.1 - 0.42 9.5 3.4 0.59 9.0 2.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RasGEF PF00617.14 KXX77602.1 - 1.1e-43 149.1 0.0 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 KXX77602.1 - 1.3e-15 57.9 0.0 4e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 KXX77602.1 - 2e-11 43.9 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 KXX77602.1 - 0.0018 17.6 0.0 0.058 12.7 0.0 2.8 2 1 0 2 2 2 1 Ras family AAA_16 PF13191.1 KXX77602.1 - 0.0028 17.6 0.2 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KXX77602.1 - 0.0031 18.3 0.0 0.054 14.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KXX77602.1 - 0.0089 15.5 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KXX77602.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KXX77602.1 - 0.021 14.0 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX77602.1 - 0.023 14.8 0.1 0.29 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 KXX77602.1 - 0.033 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KXX77602.1 - 0.042 14.1 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KXX77602.1 - 0.042 13.2 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX77602.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KXX77602.1 - 0.07 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 KXX77602.1 - 0.083 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 KXX77602.1 - 0.095 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KXX77602.1 - 0.13 11.7 0.0 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 KXX77602.1 - 0.14 11.5 0.1 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase G-alpha PF00503.15 KXX77602.1 - 0.17 10.5 0.0 0.99 8.0 0.0 2.0 2 1 0 2 2 2 0 G-protein alpha subunit PIG-H PF10181.4 KXX77603.1 - 1.1e-25 89.0 0.0 1.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component zf-CCCH PF00642.19 KXX77604.1 - 1.6e-05 24.4 0.9 1.6e-05 24.4 0.6 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tyrosinase PF00264.15 KXX77605.1 - 4.5e-52 177.4 2.2 6.5e-52 176.8 1.6 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Nfu_N PF08712.6 KXX77606.1 - 5.5e-29 99.6 0.1 1.8e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KXX77606.1 - 1.1e-20 73.1 0.0 1.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 KXX77607.1 - 4.8e-31 106.5 0.7 8.2e-31 105.8 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-HIT PF04438.11 KXX77609.1 - 2.8e-12 46.0 10.4 4.6e-12 45.3 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KXX77609.1 - 0.00013 21.7 7.2 0.00019 21.2 5.0 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 KXX77609.1 - 0.61 10.0 4.9 0.97 9.3 3.4 1.3 1 0 0 1 1 1 0 B-box zinc finger PAT1 PF09770.4 KXX77609.1 - 4 5.5 6.1 4.7 5.3 4.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-Mss51 PF13824.1 KXX77609.1 - 6 6.8 8.1 16 5.4 5.6 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Lipase_3 PF01764.20 KXX77610.1 - 9.9e-21 73.8 0.0 1.8e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KXX77610.1 - 0.056 12.7 0.1 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF89 PF01937.14 KXX77611.1 - 1.5e-10 40.4 0.1 1.6e-10 40.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 ABC_tran PF00005.22 KXX77612.1 - 2.9e-46 157.1 0.0 9.1e-23 81.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KXX77612.1 - 6e-22 77.2 1.5 6e-22 77.2 1.0 3.0 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 KXX77612.1 - 1.4e-19 71.1 0.1 5.6e-05 23.2 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KXX77612.1 - 2.2e-11 43.3 0.1 0.0081 15.4 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX77612.1 - 2.3e-09 36.6 0.4 0.00091 18.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX77612.1 - 1.7e-08 35.0 4.7 0.028 14.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KXX77612.1 - 2.7e-07 31.4 0.2 0.0042 17.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KXX77612.1 - 1.4e-06 28.5 0.0 0.049 13.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX77612.1 - 3.2e-06 26.4 0.0 0.0047 16.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX77612.1 - 6.8e-06 26.2 0.0 0.2 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KXX77612.1 - 1.5e-05 25.4 0.0 0.035 14.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 KXX77612.1 - 2.1e-05 24.0 0.0 0.1 11.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KXX77612.1 - 2.4e-05 24.2 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 KXX77612.1 - 2.6e-05 24.1 0.0 0.35 10.7 0.1 3.4 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 KXX77612.1 - 2.6e-05 23.9 0.1 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 KXX77612.1 - 3.6e-05 23.9 0.0 0.21 11.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KXX77612.1 - 3.7e-05 23.7 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX77612.1 - 4.7e-05 23.4 4.4 0.24 11.3 0.1 3.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 KXX77612.1 - 0.00011 21.8 0.2 0.47 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KXX77612.1 - 0.00016 21.8 2.2 1.6 8.9 0.0 3.4 3 0 0 3 3 3 2 RNA helicase Arch_ATPase PF01637.13 KXX77612.1 - 0.00032 20.4 0.1 0.29 10.7 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_15 PF13175.1 KXX77612.1 - 0.00033 19.8 0.0 0.13 11.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KXX77612.1 - 0.00036 20.0 1.4 0.45 9.9 0.2 3.0 4 0 0 4 4 3 2 AAA-like domain Dynamin_N PF00350.18 KXX77612.1 - 0.0007 19.4 0.5 1.3 8.8 0.0 3.4 3 1 1 4 4 4 1 Dynamin family AAA_14 PF13173.1 KXX77612.1 - 0.00075 19.3 0.0 1.7 8.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KXX77612.1 - 0.0011 18.6 0.2 0.052 13.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KXX77612.1 - 0.0098 14.7 0.0 1.4 7.6 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain SbcCD_C PF13558.1 KXX77612.1 - 0.011 15.5 0.6 0.68 9.8 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2813 PF11398.3 KXX77612.1 - 0.012 14.7 2.3 0.85 8.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 KXX77612.1 - 0.017 14.0 0.8 2.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 KXX77612.1 - 0.05 12.5 0.1 3.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KXX77612.1 - 0.056 12.9 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KXX77612.1 - 0.071 12.5 0.5 5.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KXX77612.1 - 0.076 12.7 1.9 4.8 6.8 0.1 2.9 3 0 0 3 3 2 0 NTPase ArgK PF03308.11 KXX77612.1 - 0.13 11.0 0.8 14 4.3 0.1 2.6 3 0 0 3 3 3 0 ArgK protein FeoB_N PF02421.13 KXX77612.1 - 0.13 11.5 0.2 8.8 5.5 0.0 2.7 3 0 0 3 3 2 0 Ferrous iron transport protein B DUF87 PF01935.12 KXX77612.1 - 0.23 11.2 2.5 13 5.4 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF3584 PF12128.3 KXX77612.1 - 4.9 4.3 6.5 0.37 8.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) SNF2_N PF00176.18 KXX77613.1 - 4.4e-72 242.3 2.9 7.5e-72 241.6 2.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KXX77613.1 - 2.1e-51 173.6 17.2 2.1e-51 173.6 11.9 4.4 3 2 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KXX77613.1 - 4.5e-16 58.4 0.0 1.4e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1700 PF08006.6 KXX77614.1 - 0.19 11.0 4.1 0.23 10.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GFO_IDH_MocA PF01408.17 KXX77615.1 - 2.3e-25 89.4 0.0 3.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KXX77615.1 - 3.7e-12 46.0 0.1 1.2e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KXX77615.1 - 0.00012 22.4 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KXX77615.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KXX77615.1 - 0.024 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase AAA_33 PF13671.1 KXX77615.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoA_binding_2 PF13380.1 KXX77615.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain adh_short PF00106.20 KXX77616.1 - 8.4e-13 48.5 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77616.1 - 3.8e-05 23.4 0.0 6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX77616.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GHMP_kinases_C PF08544.8 KXX77616.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Glyco_hydro_72 PF03198.9 KXX77617.1 - 8.1e-124 412.6 2.8 1e-123 412.3 1.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KXX77617.1 - 7.4e-23 80.8 3.9 2.1e-22 79.4 2.7 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KXX77617.1 - 3.9e-05 22.7 0.3 6.3e-05 22.0 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_GJ PF03229.8 KXX77617.1 - 0.062 13.6 7.2 0.17 12.2 5.0 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Lipoxygenase PF00305.14 KXX77619.1 - 2.7e-57 194.2 2.8 4.6e-57 193.4 1.9 1.3 1 1 0 1 1 1 1 Lipoxygenase DUF2305 PF10230.4 KXX77620.1 - 3.7e-65 219.9 0.0 4.4e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KXX77620.1 - 7.1e-09 35.8 0.3 1.2e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX77620.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX77620.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KXX77620.1 - 0.058 12.9 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FHA PF00498.21 KXX77620.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 FHA domain Abhydrolase_1 PF00561.15 KXX77620.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ABC2_membrane_4 PF12730.2 KXX77621.1 - 1.9 7.6 10.0 4.2 6.4 0.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_10 PF00331.15 KXX77622.1 - 3.5e-87 292.4 0.0 4.4e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF1305 PF06996.6 KXX77622.1 - 0.083 11.9 0.1 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) Fungal_trans_2 PF11951.3 KXX77623.1 - 1.7e-05 23.6 0.1 2.2e-05 23.2 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.5 KXX77624.1 - 6.4e-13 48.8 0.1 1.3e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 CVNH domain EGF_3 PF12947.2 KXX77624.1 - 4.5 7.3 9.3 15 5.6 0.2 3.2 3 1 0 3 3 3 0 EGF domain Spherulin4 PF12138.3 KXX77625.1 - 9.3e-11 41.6 0.0 3e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Spherulation-specific family 4 RAI16-like PF10257.4 KXX77626.1 - 1.6e-80 270.6 2.8 2.9e-80 269.8 2.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FAD_binding_4 PF01565.18 KXX77628.1 - 8.1e-25 86.9 5.6 1.3e-24 86.2 3.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX77628.1 - 1.1e-11 44.3 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Augurin PF15187.1 KXX77628.1 - 0.004 17.0 1.7 0.0047 16.7 0.3 1.8 2 0 0 2 2 2 1 Oesophageal cancer-related gene 4 GFA PF04828.9 KXX77629.1 - 5.7e-20 71.0 4.5 2.9e-09 36.7 0.1 3.8 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 KXX77629.1 - 0.055 13.3 0.9 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Rpr2 PF04032.11 KXX77629.1 - 0.17 11.7 2.9 5.5 6.9 0.0 2.9 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 KXX77629.1 - 0.63 9.3 3.9 3.1 7.1 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 KXX77629.1 - 0.64 9.9 8.1 0.08 12.8 1.3 2.6 3 0 0 3 3 3 0 Cysteine-rich CWC zinc_ribbon_2 PF13240.1 KXX77629.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Ytp1 PF10355.4 KXX77630.1 - 8.1e-84 281.0 15.3 1.3e-83 280.2 10.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KXX77630.1 - 5.7e-33 112.6 0.8 5.7e-33 112.6 0.5 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF897 PF05982.7 KXX77630.1 - 0.0014 17.4 2.1 0.0036 16.1 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF897) Peptidase_M20 PF01546.23 KXX77631.1 - 1.1e-07 31.5 0.9 2.9e-07 30.1 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KXX77631.1 - 1e-05 25.2 0.0 2.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Oxidored_FMN PF00724.15 KXX77632.1 - 3.7e-50 170.8 0.0 1.3e-42 146.0 0.0 2.3 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KXX77632.1 - 0.0088 14.9 0.1 0.036 12.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.19 KXX77632.1 - 0.018 14.3 0.1 0.036 13.3 0.1 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Arylesterase PF01731.15 KXX77633.1 - 0.017 15.0 0.0 0.14 12.1 0.0 2.5 2 1 0 2 2 2 0 Arylesterase Glyco_hydro_62 PF03664.8 KXX77634.1 - 3.5e-144 478.8 8.4 4.1e-144 478.6 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KXX77634.1 - 0.00021 20.8 5.0 0.00046 19.7 3.4 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3176 PF11374.3 KXX77635.1 - 1.8e-31 108.3 0.4 4.3e-31 107.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) NTP_transf_3 PF12804.2 KXX77636.1 - 2e-30 106.0 0.5 6.9e-30 104.2 0.3 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain Abhydrolase_6 PF12697.2 KXX77637.1 - 1.3e-19 71.0 0.4 1.8e-19 70.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX77637.1 - 3.4e-12 46.3 0.0 4.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX77637.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KXX77637.1 - 0.036 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KXX77637.1 - 0.096 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 KXX77637.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) CMAS PF02353.15 KXX77638.1 - 3.2e-62 210.0 0.1 4.1e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KXX77638.1 - 3.4e-13 49.6 0.0 6.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77638.1 - 1.2e-06 28.8 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77638.1 - 0.0002 21.7 0.0 0.00041 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77638.1 - 0.00046 20.4 0.0 0.00091 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77638.1 - 0.00048 20.6 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77638.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX77638.1 - 0.0019 18.2 0.0 0.015 15.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX77638.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 KXX77638.1 - 0.039 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 KXX77638.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MoCF_biosynth PF00994.19 KXX77639.1 - 2.2e-27 95.2 0.0 3.2e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 KXX77639.1 - 9.5e-25 86.8 0.0 1.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) DMRL_synthase PF00885.14 KXX77639.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase MoeA_C PF03454.10 KXX77639.1 - 0.019 14.9 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Molybdopterin PF00384.17 KXX77641.1 - 6.3e-70 236.0 0.0 8e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 KXX77641.1 - 1.6e-27 95.4 0.0 3.3e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 KXX77641.1 - 4.7e-11 42.3 1.7 1.1e-10 41.1 1.2 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Gemini_AL1_M PF08283.6 KXX77641.1 - 0.012 15.3 0.1 1.3 8.8 0.0 2.9 2 1 1 3 3 3 0 Geminivirus rep protein central domain Fungal_trans PF04082.13 KXX77642.1 - 0.0011 17.8 0.0 0.0027 16.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77642.1 - 0.11 12.4 5.8 0.23 11.3 4.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KXX77642.1 - 0.81 9.8 5.6 1.7 8.8 3.9 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region His_Phos_1 PF00300.17 KXX77643.1 - 9.4e-14 51.7 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mem_trans PF03547.13 KXX77644.1 - 0.12 10.6 2.1 0.22 9.7 1.4 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF4173 PF13777.1 KXX77644.1 - 4.2 6.6 9.0 0.67 9.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF1053 PF06327.9 KXX77646.1 - 0.0069 16.7 1.6 0.15 12.4 1.9 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1053) Peptidase_C37 PF05416.7 KXX77646.1 - 0.84 7.8 5.2 1.3 7.2 3.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase SGL PF08450.7 KXX77651.1 - 3e-05 23.5 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 KXX77651.1 - 0.037 13.7 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Toxin_22 PF08092.6 KXX77651.1 - 0.099 12.4 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 Magi peptide toxin family PRCH PF03967.8 KXX77651.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region GMC_oxred_N PF00732.14 KXX77652.1 - 2.2e-45 155.1 0.0 3e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX77652.1 - 7.8e-32 110.5 0.0 2.4e-31 108.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KXX77652.1 - 0.014 14.3 0.0 0.065 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX77652.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX77652.1 - 0.04 12.7 0.0 8.1 5.1 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 KXX77652.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KXX77652.1 - 0.099 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PG_binding_1 PF01471.13 KXX77654.1 - 9.1e-10 38.3 0.3 5.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.5 KXX77654.1 - 0.00012 21.9 0.0 0.094 12.7 0.0 2.2 1 1 1 2 2 2 2 Predicted Peptidoglycan domain adh_short PF00106.20 KXX77656.1 - 1e-11 45.0 0.4 2.5e-11 43.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KXX77656.1 - 0.0087 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KXX77656.1 - 0.011 15.3 0.5 0.031 13.9 0.3 1.8 1 1 1 2 2 2 0 KR domain DUF1993 PF09351.5 KXX77657.1 - 3.2e-45 153.9 0.0 3.7e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1479 PF07350.7 KXX77658.1 - 1.3e-156 521.3 0.0 1.4e-156 521.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KXX77658.1 - 0.0011 19.0 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) OB_NTP_bind PF07717.11 KXX77659.1 - 9.1e-25 86.7 0.0 1.6e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KXX77659.1 - 4.4e-21 74.8 0.1 1e-20 73.6 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KXX77659.1 - 6.4e-07 29.1 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KXX77659.1 - 0.0004 20.5 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KXX77659.1 - 0.018 14.5 0.1 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 KXX77659.1 - 0.021 14.3 0.4 0.12 11.8 0.3 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 KXX77659.1 - 0.066 12.6 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KXX77659.1 - 0.082 13.2 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KXX77659.1 - 0.11 12.2 0.1 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KXX77659.1 - 0.11 11.5 0.2 0.39 9.7 0.1 1.9 1 1 1 2 2 2 0 Zeta toxin Mid2 PF04478.7 KXX77660.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 KXX77660.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Snf7 PF03357.16 KXX77661.1 - 1.5e-34 118.8 6.5 1.8e-34 118.5 4.5 1.1 1 0 0 1 1 1 1 Snf7 DUF2293 PF10056.4 KXX77662.1 - 2.5e-28 97.8 0.1 8.1e-28 96.2 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Dicty_REP PF05086.7 KXX77662.1 - 0.52 7.9 1.0 0.71 7.5 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.2 KXX77663.1 - 7.2e-45 151.2 0.0 1.1e-11 44.9 0.0 5.1 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SPX PF03105.14 KXX77663.1 - 6.7e-28 98.2 13.2 4.6e-15 56.1 3.2 2.5 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KXX77663.1 - 6e-26 90.3 5.5 2.9e-09 37.2 0.0 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KXX77663.1 - 1.3e-22 78.3 18.0 9.5e-05 22.0 0.0 8.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KXX77663.1 - 7.5e-21 73.6 11.7 5.3e-05 23.3 0.0 8.2 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77663.1 - 1.3e-13 49.7 14.6 0.0045 17.1 0.0 7.9 9 0 0 9 9 9 3 Ankyrin repeat GDPD PF03009.12 KXX77663.1 - 5.5e-05 22.7 0.0 0.0025 17.3 0.0 2.8 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.1 KXX77663.1 - 0.11 11.8 2.4 0.9 8.8 0.1 2.6 2 0 0 2 2 2 0 Ribosome-assembly protein 3 CUE PF02845.11 KXX77664.1 - 5.8e-13 48.0 0.0 1.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain Glyoxalase PF00903.20 KXX77665.1 - 3.2e-21 75.6 0.1 8.4e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KXX77665.1 - 9e-12 44.9 0.0 2.9e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX77665.1 - 5.1e-11 43.1 0.0 6.8e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KXX77665.1 - 2.9e-05 24.0 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KXX77665.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Enterotoxin_a PF01375.12 KXX77665.1 - 0.0039 16.5 0.3 0.0068 15.7 0.2 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain TPR_11 PF13414.1 KXX77666.1 - 0.0017 17.9 0.1 1.2 8.7 0.1 2.5 2 0 0 2 2 2 2 TPR repeat HisKA PF00512.20 KXX77666.1 - 0.022 14.7 0.3 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TPR_12 PF13424.1 KXX77666.1 - 0.029 14.3 0.7 0.57 10.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77666.1 - 0.036 14.7 1.5 0.25 12.0 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2665 PF11654.3 KXX77667.1 - 7.7e-09 34.9 0.0 8.8e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF21 PF01595.15 KXX77667.1 - 0.059 12.6 0.0 0.062 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF21 Ribosomal_L27e PF01777.13 KXX77668.1 - 3.4e-38 129.6 4.6 4.4e-38 129.2 3.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KXX77668.1 - 0.011 15.4 0.1 0.04 13.6 0.1 1.9 1 0 0 1 1 1 0 KOW motif DUF1922 PF09082.5 KXX77668.1 - 0.04 13.9 0.1 0.079 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) ECM11 PF15463.1 KXX77668.1 - 0.12 12.6 1.3 0.17 12.1 0.2 1.6 2 0 0 2 2 2 0 Extracellular mutant protein 11 TPT PF03151.11 KXX77669.1 - 1.6e-29 102.5 12.9 1.6e-29 102.5 9.0 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KXX77669.1 - 0.019 13.8 25.7 0.017 14.0 4.2 2.3 2 0 0 2 2 2 0 UAA transporter family EamA PF00892.15 KXX77669.1 - 3 7.8 42.2 0.21 11.6 11.2 2.8 3 1 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.1 KXX77670.1 - 9.9e-10 38.3 0.1 2.1e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KXX77670.1 - 2e-07 30.4 0.0 8.1e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KXX77670.1 - 7.4e-05 22.8 0.8 0.00015 21.8 0.1 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX77670.1 - 0.0059 16.5 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX77670.1 - 0.039 12.4 0.1 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KXX77670.1 - 0.08 12.7 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1344 PF07076.6 KXX77670.1 - 0.11 12.1 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Thi4 PF01946.12 KXX77670.1 - 0.11 11.5 0.2 0.27 10.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 KXX77670.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HATPase_c PF02518.21 KXX77671.1 - 2.4e-28 98.0 0.1 1.5e-27 95.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KXX77671.1 - 1.5e-21 76.4 0.9 4.7e-21 74.9 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KXX77671.1 - 9.7e-20 70.3 0.4 3.9e-19 68.4 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KXX77671.1 - 3.6e-15 56.4 2.3 5.9e-15 55.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain GAF_2 PF13185.1 KXX77671.1 - 7.5e-09 36.2 0.0 1.9e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KXX77671.1 - 1.2e-07 31.1 0.0 3.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 KXX77671.1 - 2.3e-07 30.9 0.0 6.8e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 GAF domain TPR_11 PF13414.1 KXX77671.1 - 1.6e-05 24.4 6.7 0.0026 17.3 0.7 4.1 4 0 0 4 4 4 1 TPR repeat HATPase_c_3 PF13589.1 KXX77671.1 - 0.00077 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.12 KXX77671.1 - 0.00096 18.2 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 KXX77671.1 - 0.0095 15.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KXX77671.1 - 0.028 14.5 0.0 6.7 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KXX77671.1 - 0.095 11.5 0.0 0.37 9.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TPR_2 PF07719.12 KXX77671.1 - 0.33 10.9 4.0 51 4.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77671.1 - 0.61 10.0 11.7 2.1 8.3 1.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77671.1 - 6.1 7.6 9.1 4.4 8.1 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2722 PF10846.3 KXX77672.1 - 1.7e-07 30.6 0.0 1.7e-07 30.6 0.0 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2722) DUF4011 PF13195.1 KXX77672.1 - 1.1 9.2 9.5 0.18 11.7 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Zip PF02535.17 KXX77672.1 - 3.9 6.3 12.3 7.5 5.4 8.5 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 KXX77672.1 - 5.1 4.6 10.7 8.2 3.9 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF853 PF05872.7 KXX77672.1 - 6.9 4.8 7.9 12 4.1 5.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Presenilin PF01080.12 KXX77672.1 - 8.5 5.0 8.3 16 4.1 5.7 1.4 1 0 0 1 1 1 0 Presenilin Ssl1 PF04056.9 KXX77673.1 - 2e-72 242.8 0.0 2.6e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KXX77673.1 - 4.7e-15 55.3 9.7 4.7e-15 55.3 6.7 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KXX77673.1 - 7.7e-07 29.3 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 KXX77673.1 - 0.011 15.6 2.1 0.011 15.6 1.5 2.9 3 1 0 3 3 3 0 IBR domain HATPase_c PF02518.21 KXX77674.1 - 4.7e-25 87.4 0.2 1e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KXX77674.1 - 1.2e-21 76.4 0.1 4.1e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KXX77674.1 - 1.3e-21 76.7 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.6 KXX77674.1 - 2.7e-19 69.0 0.6 6.4e-11 42.2 0.1 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KXX77674.1 - 1.7e-12 47.5 0.0 1.8e-06 28.2 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 KXX77674.1 - 4.8e-07 29.5 0.0 0.031 14.0 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KXX77674.1 - 1.7e-06 28.0 0.5 6e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 KXX77674.1 - 0.015 15.1 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 0 PAS domain S10_plectin PF03501.10 KXX77675.1 - 7.2e-37 125.1 0.2 8.9e-37 124.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 KXX77676.1 - 1.8e-24 85.6 0.1 1.2e-23 82.9 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX77676.1 - 1.4e-14 53.7 0.0 2.2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX77676.1 - 7.1e-06 26.9 0.0 1.3e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KXX77676.1 - 0.0016 17.5 0.2 0.0031 16.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KXX77676.1 - 0.027 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KXX77676.1 - 0.028 14.5 0.0 0.072 13.1 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KXX77676.1 - 0.15 12.0 0.3 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain COX6B PF02297.12 KXX77677.1 - 9.8e-19 67.1 4.6 1.2e-18 66.9 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KXX77677.1 - 0.0033 16.7 0.4 0.0046 16.3 0.2 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 KXX77677.1 - 0.09 12.2 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CHCH PF06747.8 KXX77677.1 - 0.17 11.8 0.5 0.44 10.5 0.3 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 KXX77677.1 - 3 7.7 5.4 4.5 7.2 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Telomere_Sde2 PF13019.1 KXX77678.1 - 4.5e-61 205.2 0.0 5.9e-61 204.8 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Serglycin PF04360.7 KXX77678.1 - 0.88 9.2 4.5 0.73 9.5 2.0 1.7 2 0 0 2 2 2 0 Serglycin RRM_1 PF00076.17 KXX77679.1 - 3.8e-17 61.6 0.0 7.4e-17 60.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77679.1 - 4.7e-16 58.5 0.0 7.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77679.1 - 1.8e-09 37.2 0.0 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureidogly_hydro PF04115.7 KXX77679.1 - 0.0048 16.2 0.1 0.65 9.3 0.0 2.1 1 1 1 2 2 2 2 Ureidoglycolate hydrolase Limkain-b1 PF11608.3 KXX77679.1 - 0.0073 16.0 0.1 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 KXX77679.1 - 0.13 12.1 0.0 0.93 9.3 0.0 2.1 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 KXX77679.1 - 0.16 11.7 0.2 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif B12D PF06522.6 KXX77680.1 - 8.7e-11 41.3 0.0 1.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DsbD_2 PF13386.1 KXX77680.1 - 0.064 12.9 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region GET2 PF08690.5 KXX77681.1 - 2.8e-13 49.8 0.0 5.9e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 WD40 PF00400.27 KXX77682.1 - 1e-24 85.4 3.1 9.1e-05 22.1 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 KXX77682.1 - 2.6e-12 46.7 3.0 3.1e-12 46.4 0.4 2.6 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KXX77682.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 2OG-FeII_Oxy_3 PF13640.1 KXX77683.1 - 5e-11 43.0 0.0 8.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KXX77683.1 - 2.2e-05 23.9 0.1 4.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 KXX77683.1 - 0.043 13.8 0.0 0.73 9.8 0.0 2.6 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_76 PF03663.9 KXX77685.1 - 2.5e-152 507.5 9.4 3.2e-152 507.2 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KXX77685.1 - 0.0021 17.1 5.7 0.072 12.1 0.1 3.0 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 RF-1 PF00472.15 KXX77686.1 - 3.6e-34 116.9 3.6 9.6e-34 115.6 2.5 1.7 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KXX77686.1 - 6.6e-27 93.5 0.0 2.5e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 PCRF domain DUF1912 PF08930.5 KXX77686.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) tRNA-synt_1b PF00579.20 KXX77687.1 - 1.5e-17 63.7 0.2 6.1e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) SAGA-Tad1 PF12767.2 KXX77688.1 - 9.6e-58 195.8 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit MRC1 PF09444.5 KXX77689.1 - 1.3e-44 152.0 19.7 1.3e-44 152.0 13.6 7.2 6 2 2 8 8 8 1 MRC1-like domain UQ_con PF00179.21 KXX77690.1 - 5.4e-50 168.4 0.1 6.1e-50 168.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX77690.1 - 3.3e-05 23.6 0.0 4.2e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX77690.1 - 0.023 14.5 1.7 0.059 13.2 1.1 1.9 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 KXX77691.1 - 2.7e-68 230.2 0.0 3.7e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KXX77691.1 - 1.9e-36 124.5 0.0 3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KXX77691.1 - 1e-28 99.9 0.0 2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KXX77691.1 - 4.5e-08 32.5 0.0 8.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 KXX77691.1 - 0.00029 19.8 0.0 0.0011 17.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 KXX77691.1 - 0.00081 18.1 0.0 0.05 12.3 0.0 2.6 1 1 2 3 3 3 2 Glutamine amidotransferases class-II GST_N_2 PF13409.1 KXX77692.1 - 7.7e-08 32.2 0.1 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX77692.1 - 7.9e-08 32.4 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX77692.1 - 2.7e-05 23.9 3.9 9.7e-05 22.1 2.7 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX77692.1 - 0.028 14.9 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KXX77693.1 - 2.4e-31 108.7 59.0 3.6e-31 108.1 40.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77693.1 - 4.3e-10 38.7 17.9 4.3e-10 38.7 12.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Amidohydro_4 PF13147.1 KXX77694.1 - 2.8e-08 34.1 1.6 4e-08 33.6 1.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KXX77694.1 - 1.4e-06 28.1 0.3 3.3e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX77694.1 - 0.0023 17.6 0.3 0.0031 17.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Spc97_Spc98 PF04130.8 KXX77695.1 - 1.3e-118 396.6 0.1 1.7e-118 396.2 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Mso1_Sec1_bdg PF14475.1 KXX77696.1 - 3.8e-19 67.7 0.0 5.8e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 KXX77697.1 - 9.3e-31 106.6 1.3 9.3e-31 106.6 0.9 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KXX77697.1 - 9.9e-23 80.1 7.9 9.9e-23 80.1 5.4 3.6 2 2 1 3 3 3 2 Mak16 protein C-terminal region Sigma54_activ_2 PF14532.1 KXX77697.1 - 0.0019 18.2 0.8 0.96 9.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain PaaX_C PF08223.6 KXX77697.1 - 0.0091 15.7 0.7 0.017 14.8 0.5 1.4 1 0 0 1 1 1 1 PaaX-like protein C-terminal domain Nop14 PF04147.7 KXX77697.1 - 0.18 9.6 33.1 0.27 9.1 23.0 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KXX77697.1 - 1 8.3 32.3 1.7 7.5 22.4 1.3 1 1 0 1 1 1 0 BUD22 CDC27 PF09507.5 KXX77697.1 - 1.7 7.7 27.3 0.49 9.5 16.4 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DnaJ PF00226.26 KXX77698.1 - 6.1e-20 70.7 0.4 9.6e-20 70.0 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 KXX77699.1 - 7.5e-66 222.2 8.3 8.4e-66 222.0 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.1 KXX77699.1 - 0.25 11.2 11.8 0.058 13.3 5.4 1.8 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain PRELI PF04707.9 KXX77700.1 - 1.6e-42 144.7 0.3 2e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 KXX77700.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_M24 PF00557.19 KXX77701.1 - 2.4e-45 154.6 0.1 3e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KXX77701.1 - 0.035 13.3 0.4 0.038 13.2 0.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_18 PF13238.1 KXX77702.1 - 1.3e-06 28.6 0.0 1.7e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX77702.1 - 2.4e-06 28.3 0.0 3.9e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KXX77702.1 - 0.00043 19.8 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KXX77702.1 - 0.00066 18.6 0.0 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 KXX77702.1 - 0.0011 18.8 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KXX77702.1 - 0.0018 17.4 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KXX77702.1 - 0.0053 16.4 0.6 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KXX77702.1 - 0.019 14.9 0.1 0.033 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KXX77702.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.5 KXX77702.1 - 0.041 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 KXX77702.1 - 0.046 14.0 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KXX77702.1 - 0.15 11.4 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase Alpha-E PF04168.7 KXX77703.1 - 1.1 8.5 5.6 5.2 6.3 3.9 2.2 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. CAP_N PF01213.14 KXX77704.1 - 0.0098 15.2 0.8 0.011 15.0 0.6 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal ABC1 PF03109.11 KXX77706.1 - 3.8e-30 104.2 0.0 6.5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Aldo_ket_red PF00248.16 KXX77707.1 - 2.9e-67 226.4 0.0 3.3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transthyretin PF00576.16 KXX77708.1 - 2.5e-25 88.5 0.2 1.8e-15 56.7 0.1 2.9 1 1 1 2 2 2 2 HIUase/Transthyretin family DUF4616 PF15394.1 KXX77709.1 - 0.088 11.8 0.1 0.096 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) SecE PF00584.15 KXX77710.1 - 1.3e-11 43.8 0.0 1.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex MKT1_C PF12246.3 KXX77711.1 - 6.9e-70 234.8 0.0 9.6e-70 234.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KXX77711.1 - 2.9e-28 98.0 0.1 8.8e-28 96.4 0.1 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KXX77711.1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 XPG I-region XPG_N PF00752.12 KXX77711.1 - 0.062 13.5 0.0 0.98 9.7 0.0 2.5 2 0 0 2 2 2 0 XPG N-terminal domain Pox_Rap94 PF03294.9 KXX77711.1 - 0.43 8.4 0.6 1 7.2 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase-associated transcription specificity factor, Rap94 Peptidase_S10 PF00450.17 KXX77712.1 - 8.5e-87 291.9 0.0 1.1e-86 291.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PRELI PF04707.9 KXX77713.1 - 6.9e-21 74.4 0.0 4e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family DWNN PF08783.6 KXX77714.1 - 7.1e-28 96.3 0.0 1.4e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KXX77714.1 - 0.0013 18.1 5.3 0.0041 16.5 3.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KXX77714.1 - 0.0099 15.7 1.5 0.0099 15.7 1.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KXX77714.1 - 0.022 14.4 0.5 0.058 13.1 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-RING_6 PF14835.1 KXX77714.1 - 0.061 13.1 1.5 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KXX77714.1 - 0.08 12.4 6.1 0.17 11.4 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KXX77714.1 - 0.16 11.6 6.6 0.4 10.3 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KXX77714.1 - 1.3 8.9 10.7 3.6 7.5 7.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KXX77714.1 - 5.2 6.8 11.7 0.36 10.6 4.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX77714.1 - 5.3 6.7 10.1 11 5.8 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.10 KXX77715.1 - 1.2e-113 379.2 0.0 1.3e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KXX77715.1 - 1.7e-16 60.1 0.2 9.3e-16 57.8 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KXX77715.1 - 1.5e-08 34.7 0.0 5.7e-08 32.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KXX77715.1 - 4.6e-06 26.0 0.0 8.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KXX77715.1 - 3.1e-05 23.5 0.1 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KXX77715.1 - 0.0068 15.8 0.1 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX77715.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KXX77715.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KXX77715.1 - 0.024 13.9 0.0 0.056 12.8 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein MipZ PF09140.6 KXX77715.1 - 0.026 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 KXX77715.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KXX77715.1 - 0.11 12.8 0.1 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KXX77715.1 - 0.16 10.8 0.2 0.4 9.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein TrmE_N PF10396.4 KXX77717.1 - 7.3e-22 77.4 0.0 1.7e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KXX77717.1 - 2.6e-21 75.8 0.1 7.5e-21 74.3 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KXX77717.1 - 4.6e-18 65.2 0.0 9.9e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX77717.1 - 7.1e-07 28.6 0.1 4.2e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KXX77717.1 - 5e-05 23.1 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KXX77717.1 - 0.00036 21.0 0.0 0.00085 19.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KXX77717.1 - 0.015 14.5 0.1 0.036 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KXX77717.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 1 1 2 2 2 0 AAA domain Glyco_hydro_3_C PF01915.17 KXX77717.1 - 0.044 13.3 0.1 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AAA PF00004.24 KXX77717.1 - 0.061 13.5 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KXX77717.1 - 0.094 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SGS PF05002.10 KXX77719.1 - 2e-28 97.9 2.7 4.6e-28 96.7 1.9 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KXX77719.1 - 3.2e-12 46.8 0.0 5.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KXX77719.1 - 3.5e-09 36.1 3.8 1.1e-08 34.6 0.5 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KXX77719.1 - 1.7e-07 30.5 0.5 0.28 10.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77719.1 - 3.8e-07 29.5 3.9 0.21 11.6 0.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77719.1 - 9.9e-06 26.0 8.4 0.00011 22.7 3.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77719.1 - 0.00017 21.4 2.7 0.29 11.0 2.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX77719.1 - 0.00032 20.7 2.5 0.00069 19.6 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KXX77719.1 - 0.00035 20.1 4.7 4.6 7.2 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77719.1 - 0.0012 19.0 3.9 0.0029 17.9 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 KXX77719.1 - 0.003 17.3 0.5 0.0071 16.1 0.4 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 KXX77719.1 - 0.17 11.7 2.7 43 4.2 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KXX77719.1 - 0.32 10.8 2.7 0.32 10.8 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_tranf_2_3 PF13641.1 KXX77720.1 - 3.2e-12 46.7 0.0 6.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KXX77720.1 - 1.5e-10 40.6 0.0 0.00019 20.7 0.0 3.4 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX77720.1 - 0.068 12.8 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 AA_permease PF00324.16 KXX77721.1 - 1.2e-134 449.3 38.1 1.4e-134 449.0 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX77721.1 - 3e-39 134.7 36.5 4e-39 134.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease nsp8 PF08717.5 KXX77722.1 - 0.0066 16.0 5.3 14 5.1 0.0 4.4 2 2 2 4 4 4 1 nsp8 replicase Ribosomal_L17 PF01196.14 KXX77722.1 - 0.024 15.2 0.6 1.9 9.1 0.0 3.5 2 2 0 2 2 2 0 Ribosomal protein L17 NTR PF01759.16 KXX77722.1 - 0.088 12.3 4.3 17 5.0 0.1 3.6 2 2 2 4 4 4 0 UNC-6/NTR/C345C module PRA-CH PF01502.13 KXX77722.1 - 0.28 10.8 2.6 58 3.4 0.0 3.5 2 2 2 4 4 4 0 Phosphoribosyl-AMP cyclohydrolase Autophagy_N PF03986.8 KXX77722.1 - 0.46 10.2 3.6 10 5.8 0.1 2.7 2 1 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain zf-U1 PF06220.7 KXX77722.1 - 0.91 9.1 3.7 23 4.6 0.1 3.1 2 1 1 3 3 3 0 U1 zinc finger Zn_peptidase PF04228.8 KXX77722.1 - 6.4 5.9 15.4 5.2 6.2 2.7 3.8 2 2 1 3 3 3 0 Putative neutral zinc metallopeptidase DUF3328 PF11807.3 KXX77723.1 - 3.3e-45 154.4 0.7 4e-45 154.1 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.15 KXX77724.1 - 2.7e-33 116.0 0.6 3.9e-33 115.4 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase gag_pre-integrs PF13976.1 KXX77724.1 - 0.023 14.3 0.4 0.054 13.1 0.3 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain ABC_tran PF00005.22 KXX77725.1 - 3.8e-39 134.1 0.0 3.3e-19 69.5 0.0 3.5 3 1 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 KXX77725.1 - 1.2e-27 97.0 26.5 6.6e-19 68.3 13.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KXX77725.1 - 9.8e-13 48.7 0.0 0.0013 18.7 0.0 4.3 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 KXX77725.1 - 8.6e-11 41.4 0.3 0.0031 16.7 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX77725.1 - 4.7e-07 29.2 0.3 0.018 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX77725.1 - 2.2e-05 24.5 1.0 0.074 13.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KXX77725.1 - 2.2e-05 25.2 0.0 0.1 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX77725.1 - 6.1e-05 22.5 0.3 0.33 10.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX77725.1 - 6.7e-05 23.0 0.1 1.4 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KXX77725.1 - 9.9e-05 22.2 0.3 0.27 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KXX77725.1 - 0.00012 21.3 0.1 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX77725.1 - 0.0002 21.7 0.1 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KXX77725.1 - 0.00036 20.0 0.5 0.71 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 KXX77725.1 - 0.00043 20.2 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KXX77725.1 - 0.00043 20.6 0.6 0.58 10.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KXX77725.1 - 0.002 17.1 0.0 0.0094 14.8 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 KXX77725.1 - 0.0022 17.6 0.1 2.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KXX77725.1 - 0.0035 17.8 0.0 0.088 13.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KXX77725.1 - 0.013 14.9 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KXX77725.1 - 0.038 13.8 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 KXX77725.1 - 0.052 12.9 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 KXX77725.1 - 0.17 10.9 0.1 8.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 KXX77725.1 - 0.19 11.5 0.2 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Guanylate_kin PF00625.16 KXX77725.1 - 0.23 10.8 0.1 0.53 9.6 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase Arch_ATPase PF01637.13 KXX77725.1 - 0.25 10.9 0.0 7 6.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Glyco_hydro_31 PF01055.21 KXX77726.1 - 4.8e-158 526.5 3.2 1.2e-157 525.2 2.5 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX77726.1 - 4.8e-08 32.7 0.3 4.8e-08 32.7 0.2 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF3328 PF11807.3 KXX77727.1 - 0.036 13.7 5.0 0.23 11.0 3.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) tRNA_int_endo PF01974.12 KXX77728.1 - 3.2e-20 71.6 0.0 7.3e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KXX77728.1 - 1.7e-06 27.4 0.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain FAD_binding_3 PF01494.14 KXX77729.1 - 4.9e-15 55.4 1.4 1.6e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KXX77729.1 - 4.1e-07 29.2 0.4 0.00066 18.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KXX77729.1 - 0.0012 18.0 0.0 0.081 11.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KXX77729.1 - 0.0032 16.3 0.4 0.0051 15.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX77729.1 - 0.0049 17.2 0.2 0.014 15.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX77729.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX77729.1 - 0.035 13.9 0.1 0.14 12.0 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX77729.1 - 0.06 11.8 0.1 0.099 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KXX77729.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 KXX77730.1 - 8e-30 103.8 0.0 1.4e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77730.1 - 5.8e-10 38.6 0.0 1.6e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Sec39 PF08314.6 KXX77732.1 - 1.5e-231 770.2 0.0 1.8e-231 769.9 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Methyltransf_PK PF05891.7 KXX77733.1 - 7.8e-79 263.9 0.0 9e-79 263.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KXX77733.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77733.1 - 3.6e-05 24.3 0.0 5.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KXX77733.1 - 0.0002 20.6 0.1 0.00055 19.1 0.0 1.7 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 KXX77733.1 - 0.0027 18.1 0.0 0.0053 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77733.1 - 0.0037 17.7 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77733.1 - 0.0095 16.2 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Succ_CoA_lig PF13607.1 KXX77733.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain GCD14 PF08704.5 KXX77734.1 - 6.4e-64 215.8 0.0 1.9e-46 158.5 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KXX77734.1 - 0.00044 20.2 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77734.1 - 0.018 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DIOX_N PF14226.1 KXX77735.1 - 2.6e-19 69.8 0.0 4.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX77735.1 - 1.8e-11 44.1 0.0 5.3e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MS_channel PF00924.13 KXX77736.1 - 5.7e-20 71.5 2.6 1.1e-19 70.6 1.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 KXX77736.1 - 0.014 15.5 0.1 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 KXX77736.1 - 0.038 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 KXX77736.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 KXX77736.1 - 0.08 12.2 0.4 0.2 11.0 0.3 1.8 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.3 KXX77736.1 - 3.3 7.7 6.6 0.36 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function Glyco_hydro_31 PF01055.21 KXX77738.1 - 2e-153 511.3 4.0 2.6e-153 511.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX77738.1 - 1.1e-24 85.9 0.4 4.7e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Peptidase_A4 PF01828.12 KXX77739.1 - 1.2e-21 76.7 0.4 5.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase A4 family DUF2580 PF10824.3 KXX77740.1 - 0.001 19.3 1.2 0.001 19.3 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2580) NDK PF00334.14 KXX77741.1 - 1.7e-54 183.2 0.0 1.9e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase TP6A_N PF04406.9 KXX77742.1 - 5.8e-20 70.7 0.0 1.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans_2 PF13249.1 KXX77743.1 - 2.3e-30 105.2 9.4 5.3e-15 55.8 0.1 5.3 3 1 3 6 6 6 5 Prenyltransferase-like Prenyltrans PF00432.16 KXX77743.1 - 1.7e-26 91.4 9.8 3.5e-08 32.8 0.0 5.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KXX77743.1 - 7.5e-25 87.0 0.0 4.9e-11 42.6 0.1 6.4 5 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 KXX77743.1 - 2.3e-06 26.9 0.0 0.7 9.0 0.0 4.4 2 1 2 4 4 4 3 Pectic acid lyase A2M_comp PF07678.9 KXX77743.1 - 2.9e-05 23.4 0.0 0.01 15.0 0.0 3.5 3 1 1 4 4 4 1 A-macroglobulin complement component Cytomega_TRL10 PF06084.6 KXX77743.1 - 0.2 11.4 0.4 0.37 10.5 0.3 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ank_2 PF12796.2 KXX77744.1 - 3.6e-19 68.8 0.0 1.4e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77744.1 - 3.7e-18 64.3 0.5 2.7e-08 33.1 0.2 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KXX77744.1 - 1.2e-15 57.4 1.5 1.5e-05 25.3 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX77744.1 - 1.5e-15 56.8 0.7 3e-08 33.6 0.2 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77744.1 - 4.3e-15 54.3 0.1 1.2e-05 25.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ketoacyl-synt_2 PF13723.1 KXX77744.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF1110 PF06533.7 KXX77744.1 - 0.11 12.2 0.1 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) p450 PF00067.17 KXX77745.1 - 3.6e-30 104.9 0.1 5e-29 101.1 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KXX77746.1 - 2.7e-25 89.5 0.8 3.7e-25 89.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX77746.1 - 0.0002 21.1 0.0 0.00046 19.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX77746.1 - 0.00064 19.3 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2789 PF10982.3 KXX77746.1 - 0.025 14.5 0.1 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Conotoxin PF02950.12 KXX77747.1 - 0.019 15.7 0.0 0.032 15.0 0.0 1.3 1 0 0 1 1 1 0 Conotoxin APH PF01636.18 KXX77749.1 - 1.7e-18 67.2 1.1 3.2e-17 63.0 0.8 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KXX77749.1 - 0.021 13.4 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Cu-oxidase_3 PF07732.10 KXX77750.1 - 2e-42 143.6 2.4 2.3e-42 143.4 0.4 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX77750.1 - 7.6e-39 132.3 7.0 1.5e-34 118.4 0.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 KXX77750.1 - 1.5e-34 119.2 0.0 1e-33 116.5 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase GatB_N PF02934.10 KXX77751.1 - 6.3e-100 333.7 0.0 8.5e-100 333.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KXX77751.1 - 1.7e-07 31.0 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 GatB domain Patatin PF01734.17 KXX77753.1 - 7.6e-07 29.2 0.1 9.7e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 KXX77754.1 - 8.3e-53 174.9 8.6 7.2e-14 51.1 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77754.1 - 2e-47 159.0 12.4 6.4e-20 70.8 0.8 4.6 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77754.1 - 3.3e-21 74.6 14.0 2.1e-09 36.9 0.2 4.9 3 1 3 6 6 6 5 TPR repeat TPR_7 PF13176.1 KXX77754.1 - 6.2e-21 72.4 6.8 0.00051 19.6 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KXX77754.1 - 1.3e-20 73.3 0.0 3.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Phosphorylase superfamily TPR_1 PF00515.23 KXX77754.1 - 2.1e-16 58.7 7.1 0.0004 19.8 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77754.1 - 2.9e-15 54.8 7.1 0.0043 16.8 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77754.1 - 9.9e-13 48.3 1.5 6.3e-05 23.5 0.2 5.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77754.1 - 1.7e-10 41.0 1.6 0.001 19.3 0.2 4.7 3 1 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 KXX77754.1 - 5.1e-09 35.3 0.0 7.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KXX77754.1 - 2.7e-08 33.8 3.4 0.0037 17.3 0.3 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KXX77754.1 - 6.4e-08 32.2 3.4 0.64 9.8 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX77754.1 - 1.2e-07 31.3 3.3 0.61 10.4 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 KXX77754.1 - 2e-07 30.7 0.0 0.56 10.8 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX77754.1 - 4.9e-07 29.8 3.1 0.71 10.6 0.0 6.2 5 1 1 6 6 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 KXX77754.1 - 1.9e-06 27.9 0.0 7.8e-06 26.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.1 KXX77754.1 - 1.2e-05 24.7 8.3 0.18 11.6 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KXX77754.1 - 0.00013 22.1 6.0 0.41 11.1 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.1 KXX77754.1 - 0.0015 18.6 0.0 0.0063 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX77754.1 - 0.0018 17.9 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF3366 PF11846.3 KXX77754.1 - 0.0019 18.1 0.7 0.055 13.3 0.1 3.0 2 1 0 2 2 1 1 Domain of unknown function (DUF3366) TPR_5 PF12688.2 KXX77754.1 - 0.0022 17.9 0.8 0.011 15.8 0.5 2.3 1 1 0 1 1 1 1 Tetratrico peptide repeat MIT PF04212.13 KXX77754.1 - 0.0069 16.2 3.7 9.2 6.2 0.0 4.0 2 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 KXX77754.1 - 0.011 14.8 4.3 0.031 13.3 0.1 3.2 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF1925 PF09094.6 KXX77754.1 - 0.023 14.6 3.7 9.8 6.2 0.0 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF1925) CRAL_TRIO PF00650.15 KXX77755.1 - 3.1e-14 52.7 0.0 4.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX77755.1 - 0.00031 20.8 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Asp PF00026.18 KXX77756.1 - 6.4e-19 68.3 0.0 8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Fea1 PF07692.6 KXX77758.1 - 0.021 13.6 0.3 0.029 13.2 0.2 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein CesT PF05932.8 KXX77759.1 - 0.028 14.2 0.3 0.066 13.0 0.1 1.7 1 1 1 2 2 2 0 Tir chaperone protein (CesT) family PGPGW PF09656.5 KXX77759.1 - 0.11 11.8 0.0 0.32 10.3 0.0 1.8 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) adh_short PF00106.20 KXX77760.1 - 3e-26 92.3 0.1 4.3e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX77760.1 - 4.8e-25 88.7 0.0 5.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX77760.1 - 1.5e-08 34.5 0.1 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX77760.1 - 0.00049 19.6 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX77760.1 - 0.018 14.7 0.0 0.059 13.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KXX77760.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2974 PF11187.3 KXX77760.1 - 0.031 13.6 0.0 0.075 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) UDPG_MGDP_dh_N PF03721.9 KXX77760.1 - 0.085 12.2 0.4 0.22 10.8 0.3 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GMC_oxred_N PF00732.14 KXX77761.1 - 4e-31 108.2 0.0 2e-29 102.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX77761.1 - 4.2e-30 104.9 0.0 1.3e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KXX77761.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX77761.1 - 0.0026 16.6 0.0 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KXX77761.1 - 0.0036 16.2 0.2 0.25 10.1 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX77761.1 - 0.038 14.0 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX77761.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1883 PF08980.5 KXX77761.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) FAD_binding_3 PF01494.14 KXX77761.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain peroxidase PF00141.18 KXX77763.1 - 1.2e-86 289.9 0.0 2.9e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 Peroxidase EthD PF07110.6 KXX77763.1 - 0.11 13.4 0.9 0.22 12.4 0.2 1.8 2 0 0 2 2 2 0 EthD domain Acetyltransf_7 PF13508.1 KXX77764.1 - 3.4e-07 30.3 0.0 6.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX77764.1 - 3.4e-06 26.9 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX77764.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KXX77765.1 - 2.3e-05 23.6 0.0 4.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KXX77765.1 - 9.6e-05 22.2 4.6 0.00055 19.7 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KXX77765.1 - 0.021 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase TPR_12 PF13424.1 KXX77766.1 - 5.3e-24 83.9 4.9 5.8e-12 45.3 0.1 4.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KXX77766.1 - 1.5e-18 66.0 4.0 1.5e-05 24.7 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 KXX77766.1 - 5.6e-16 58.2 0.0 9e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 KXX77766.1 - 6.1e-10 39.2 3.6 0.00021 21.5 0.2 4.7 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KXX77766.1 - 1.6e-09 37.5 0.9 0.0097 16.3 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77766.1 - 2.2e-08 34.5 0.9 2.9e-05 24.5 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX77766.1 - 5.7e-08 32.7 3.3 0.15 12.7 0.1 5.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KXX77766.1 - 9.9e-08 32.0 6.8 0.013 15.5 0.1 4.5 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX77766.1 - 1.8e-07 30.5 1.0 0.54 10.3 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 KXX77766.1 - 1.2e-06 28.6 0.0 4e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77766.1 - 2.6e-06 27.5 0.9 3.6e-05 23.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.1 KXX77766.1 - 4.3e-06 26.1 1.2 0.062 13.1 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX77766.1 - 5.4e-06 26.4 0.3 0.0098 16.0 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 KXX77766.1 - 6.3e-06 25.9 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DAP3 PF10236.4 KXX77766.1 - 0.00042 19.3 0.1 0.046 12.6 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 TPR_9 PF13371.1 KXX77766.1 - 0.0017 18.1 0.4 0.29 10.9 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX77766.1 - 0.0017 17.9 0.3 0.083 12.5 0.0 2.8 2 1 2 4 4 3 2 TPR repeat TPR_4 PF07721.9 KXX77766.1 - 0.0022 18.2 6.1 0.29 11.7 0.6 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX77766.1 - 0.0031 17.5 0.0 7.7 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX77766.1 - 0.0099 15.4 0.0 6.7 6.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KXX77766.1 - 0.033 14.1 0.9 3.8 7.4 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.1 KXX77766.1 - 0.036 13.4 0.0 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 KXX77767.1 - 3.4e-73 246.7 24.7 4.2e-73 246.4 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX77767.1 - 8.3e-24 83.9 30.1 8.3e-24 83.9 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MerR-DNA-bind PF09278.6 KXX77767.1 - 0.13 12.6 0.5 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 MerR, DNA binding NACHT PF05729.7 KXX77768.1 - 0.00035 20.2 0.2 0.00075 19.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain YPEB PF14620.1 KXX77768.1 - 0.0034 16.4 1.2 0.0054 15.7 0.4 1.5 1 1 0 1 1 1 1 YpeB sporulation AAA_22 PF13401.1 KXX77768.1 - 0.024 14.7 0.0 0.097 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KXX77768.1 - 0.31 10.8 1.8 24 4.7 0.1 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus cwf21 PF08312.7 KXX77768.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.1 3 0 0 3 3 3 0 cwf21 domain MFS_1 PF07690.11 KXX77770.1 - 6.9e-29 100.6 25.6 4.4e-28 98.0 17.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KXX77770.1 - 1.8e-05 23.3 6.4 1.8e-05 23.3 4.4 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1049 PF06305.6 KXX77770.1 - 0.041 13.3 3.2 0.11 12.0 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PLAC8 PF04749.12 KXX77772.1 - 4.5e-21 75.4 11.9 5.6e-21 75.0 8.2 1.1 1 0 0 1 1 1 1 PLAC8 family FAA_hydrolase PF01557.13 KXX77773.1 - 3.8e-50 170.3 0.0 7e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KXX77773.1 - 2.6e-26 91.6 0.0 4.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal RNase_H PF00075.19 KXX77774.1 - 5e-08 33.3 0.0 7.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 RNase H WD40 PF00400.27 KXX77775.1 - 6.6e-31 105.0 9.7 1.2e-15 56.6 0.4 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1652 PF07865.6 KXX77775.1 - 2.7e-06 26.8 0.0 0.36 10.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1652) Nup160 PF11715.3 KXX77775.1 - 2.4e-05 22.6 0.3 0.19 9.8 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KXX77775.1 - 0.0005 18.0 0.7 0.3 8.8 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Nbas_N PF15492.1 KXX77775.1 - 0.0051 15.9 1.4 0.56 9.2 0.1 2.1 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 KXX77775.1 - 0.009 15.4 0.5 0.14 11.5 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain eIF2A PF08662.6 KXX77775.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KXX77775.1 - 0.015 14.7 0.1 0.53 9.6 0.1 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Plectin PF00681.15 KXX77775.1 - 0.017 14.6 0.0 13 5.3 0.0 3.2 3 0 0 3 3 3 0 Plectin repeat Big_3_4 PF13754.1 KXX77775.1 - 0.029 14.6 2.5 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SRP9-21 PF05486.7 KXX77775.1 - 0.041 13.6 0.0 14 5.5 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) Aldolase_II PF00596.16 KXX77775.1 - 0.065 12.8 0.4 8.1 6.0 0.0 2.2 1 1 1 2 2 2 0 Class II Aldolase and Adducin N-terminal domain WXG100 PF06013.7 KXX77775.1 - 0.073 13.0 0.0 2.2 8.3 0.0 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG HARP PF07443.8 KXX77775.1 - 0.13 11.6 0.2 17 4.8 0.0 2.7 2 0 0 2 2 2 0 HepA-related protein (HARP) WWE PF02825.15 KXX77775.1 - 0.17 11.2 4.2 5.3 6.5 0.2 2.2 2 0 0 2 2 2 0 WWE domain Phage_ASH PF10554.4 KXX77775.1 - 0.2 12.0 1.6 8.3 6.7 0.2 2.2 1 1 1 2 2 2 0 Ash protein family DUF2306 PF10067.4 KXX77776.1 - 0.0093 16.0 2.4 0.0093 16.0 1.7 2.8 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) Cytochrom_B561 PF03188.11 KXX77776.1 - 0.025 14.3 10.5 0.43 10.4 7.7 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Adeno_E3 PF06040.6 KXX77776.1 - 0.34 10.8 2.4 11 6.0 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF805 PF05656.9 KXX77776.1 - 0.97 9.2 15.1 1.5 8.6 1.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF805) Ni_hydr_CYTB PF01292.15 KXX77776.1 - 1.3 8.4 12.7 6.5 6.1 8.0 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 UPF0104 PF03706.8 KXX77776.1 - 9.2 5.4 19.3 0.63 9.2 3.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) CPDase PF07823.6 KXX77779.1 - 3.2e-18 65.9 0.0 2.2e-13 50.1 0.0 2.0 1 1 1 2 2 2 2 Cyclic phosphodiesterase-like protein SH3_3 PF08239.6 KXX77780.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.8 KXX77780.1 - 0.0081 15.6 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial SH3 domain Tfb2 PF03849.9 KXX77783.1 - 2.5e-139 463.9 0.0 3.4e-139 463.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KXX77783.1 - 2.2e-06 27.4 0.0 6.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.2 KXX77785.1 - 2.6e-06 27.0 0.1 6.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX77785.1 - 0.00063 19.3 1.7 0.0027 17.3 1.2 2.1 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KXX77785.1 - 0.052 13.2 0.1 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain Pkinase PF00069.20 KXX77786.1 - 1.7e-25 89.6 0.0 4e-25 88.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77786.1 - 1.9e-09 36.9 0.0 9.4e-09 34.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1376 PF07120.6 KXX77786.1 - 0.0051 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1376) APH PF01636.18 KXX77786.1 - 0.02 14.6 0.4 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PBP_GOBP PF01395.17 KXX77786.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 PBP/GOBP family Kdo PF06293.9 KXX77786.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT PF03061.17 KXX77788.1 - 5.2e-12 45.7 0.1 7.7e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KXX77788.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) MT0933_antitox PF14013.1 KXX77789.1 - 1.4 9.0 8.9 6.2 7.0 6.1 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein HMGL-like PF00682.14 KXX77790.1 - 1.2e-69 234.6 0.2 2.7e-69 233.4 0.1 1.7 2 0 0 2 2 2 1 HMGL-like NRDE PF05742.7 KXX77791.1 - 4.2e-35 121.3 0.0 8.2e-19 67.9 0.0 3.1 3 0 0 3 3 3 3 NRDE protein adh_short PF00106.20 KXX77792.1 - 1.7e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KXX77792.1 - 0.017 15.0 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding F-box-like PF12937.2 KXX77794.1 - 8.8e-09 34.9 0.3 0.0016 18.1 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KXX77794.1 - 1.7e-07 30.6 7.3 0.0018 17.8 0.0 3.0 3 0 0 3 3 3 2 F-box domain Fungal_trans PF04082.13 KXX77795.1 - 1.1e-11 44.0 0.4 2.7e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77795.1 - 1.1e-06 28.4 7.4 2.1e-06 27.5 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3138 PF11336.3 KXX77795.1 - 0.056 11.6 0.0 0.096 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_M43 PF05572.8 KXX77796.1 - 3.5e-19 68.9 0.2 4.8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KXX77796.1 - 1.1e-07 32.4 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX77796.1 - 4e-07 30.1 0.1 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX77796.1 - 1.1e-06 28.8 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KXX77796.1 - 0.0018 17.8 1.1 0.0027 17.2 0.7 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KXX77796.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KXX77796.1 - 0.09 11.6 0.5 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.6 KXX77796.1 - 0.098 12.4 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M54 DUF1025 PF06262.6 KXX77796.1 - 0.14 12.0 0.4 0.28 10.9 0.3 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase 2OG-FeII_Oxy_2 PF13532.1 KXX77797.1 - 1.8e-18 67.1 0.0 3.7e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KXX77797.1 - 1.1e-08 35.2 0.1 6.1e-07 29.6 0.0 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KXX77797.1 - 0.07 13.6 0.2 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Cu-oxidase_3 PF07732.10 KXX77798.1 - 8.4e-42 141.6 0.9 8.4e-42 141.6 0.6 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX77798.1 - 2.9e-31 107.8 9.9 5.4e-24 84.2 1.4 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KXX77798.1 - 2.8e-13 50.0 0.0 2.2e-10 40.6 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase 4HBT PF03061.17 KXX77801.1 - 3.6e-07 30.1 0.5 1.1e-06 28.6 0.2 1.9 2 1 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 KXX77802.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily SKG6 PF08693.5 KXX77803.1 - 0.0041 16.3 0.4 0.0041 16.3 0.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain ATP-grasp_4 PF13535.1 KXX77804.1 - 2.1e-19 69.9 0.1 1.6e-17 63.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KXX77804.1 - 6.7e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Collagen PF01391.13 KXX77804.1 - 0.0003 20.2 3.3 0.00051 19.5 2.3 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) ATP-grasp_3 PF02655.9 KXX77804.1 - 0.0048 16.7 2.3 0.0055 16.5 0.0 2.2 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KXX77804.1 - 0.028 13.1 0.0 3.6 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon NAS PF03059.11 KXX77805.1 - 5.7e-71 238.9 0.0 7.2e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Rhodanese PF00581.15 KXX77807.1 - 1e-09 38.7 0.0 1.6e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Dioxygenase_C PF00775.16 KXX77809.1 - 5e-08 32.4 0.2 1.1e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase NAD_binding_10 PF13460.1 KXX77811.1 - 2.9e-08 33.9 0.1 9.6e-08 32.2 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KXX77811.1 - 7.5e-07 28.8 0.0 9.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX77811.1 - 0.0016 17.2 0.0 0.0024 16.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KXX77811.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Hexapep PF00132.19 KXX77812.1 - 3.3e-08 32.6 6.6 4.3e-05 22.8 0.5 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KXX77812.1 - 0.0013 18.2 1.9 0.011 15.2 0.1 2.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KXX77812.1 - 0.034 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase CorA PF01544.13 KXX77813.1 - 7.1e-07 28.5 0.1 1.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2011 PF09428.5 KXX77814.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) SIS PF01380.17 KXX77815.1 - 8e-13 48.1 0.3 2.7e-12 46.4 0.0 2.0 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KXX77815.1 - 0.0025 17.5 0.0 0.043 13.5 0.1 2.2 1 1 1 2 2 2 1 SIS domain LMWPc PF01451.16 KXX77816.1 - 1.6e-36 125.6 0.0 1.8e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Proteasome PF00227.21 KXX77817.1 - 2.6e-47 160.5 0.0 3.4e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX77817.1 - 1.9e-13 49.4 0.1 1.9e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.4 KXX77818.1 - 5.2e-22 77.1 2.3 5.3e-22 77.1 0.3 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Pkinase PF00069.20 KXX77819.1 - 2.6e-71 239.8 0.0 3.1e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77819.1 - 4.2e-31 107.9 0.0 6e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX77819.1 - 0.021 14.5 0.1 0.068 12.8 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KXX77819.1 - 0.087 11.8 0.0 0.23 10.5 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3455 PF11937.3 KXX77820.1 - 4.8e-28 98.3 0.0 6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) zf-C2HC_2 PF13913.1 KXX77821.1 - 0.031 13.9 1.4 0.031 13.9 1.0 2.8 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KXX77821.1 - 0.12 12.7 0.3 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX77821.1 - 0.17 12.2 8.9 0.24 11.8 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 KXX77821.1 - 0.86 9.7 6.8 4 7.6 0.3 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DOCK-C2 PF14429.1 KXX77822.1 - 5.8e-23 81.4 0.0 9.6e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KXX77822.1 - 7e-09 35.2 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KXX77822.1 - 4.4e-06 25.9 0.0 1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX77822.1 - 0.0013 18.2 0.0 0.0077 15.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain CN_hydrolase PF00795.17 KXX77825.1 - 8.8e-21 74.0 0.0 1.3e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cupin_5 PF06172.6 KXX77826.1 - 2.1e-37 128.1 0.1 3.5e-37 127.4 0.0 1.4 2 0 0 2 2 2 1 Cupin superfamily (DUF985) DUF1999 PF09390.5 KXX77826.1 - 0.098 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Glyco_hydro_61 PF03443.9 KXX77827.1 - 9.6e-25 87.6 0.0 5e-22 78.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 SDA1 PF05285.7 KXX77828.1 - 1.7e-86 290.4 35.8 1.7e-86 290.4 24.8 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KXX77828.1 - 1.7e-22 79.4 0.1 5e-22 77.9 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Ank_2 PF12796.2 KXX77829.1 - 2.5e-41 139.9 1.1 8.5e-17 61.2 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77829.1 - 1.4e-32 109.8 3.2 4.4e-05 23.0 0.0 9.7 9 2 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 KXX77829.1 - 6.4e-25 87.0 0.0 8.5e-08 32.5 0.0 7.0 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77829.1 - 1.9e-21 74.0 1.2 0.0048 17.0 0.0 8.2 7 2 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KXX77829.1 - 1.4e-20 72.7 0.1 1.4e-07 31.4 0.0 5.7 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Dioxygenase_C PF00775.16 KXX77831.1 - 4.2e-11 42.4 0.1 6.2e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.15 KXX77832.1 - 5.9e-32 111.6 0.7 7.4e-32 111.2 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Methyltransf_23 PF13489.1 KXX77833.1 - 4.7e-10 39.4 0.0 6.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77833.1 - 0.0018 18.7 0.0 0.0052 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77833.1 - 0.0053 17.2 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Toxin_57 PF15535.1 KXX77835.1 - 0.7 9.9 3.3 2.1 8.4 0.5 2.3 1 1 1 2 2 2 0 Putative toxin 57 bZIP_1 PF00170.16 KXX77836.1 - 4.2e-10 39.4 11.0 4.2e-10 39.4 7.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KXX77836.1 - 0.0004 20.1 10.4 0.0004 20.1 7.2 2.7 2 0 0 2 2 2 1 Basic region leucine zipper TFIIA PF03153.8 KXX77836.1 - 1.1 9.0 37.3 3.7 7.3 4.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.8 KXX77836.1 - 1.5 7.5 25.8 0.056 12.2 6.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 KXX77836.1 - 6.3 4.9 57.2 0.73 7.9 19.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.9 KXX77836.1 - 7 6.2 7.9 2.1 7.9 1.4 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Fungal_trans_2 PF11951.3 KXX77837.1 - 3.9e-19 68.5 0.0 5e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_5 PF13857.1 KXX77838.1 - 5.3e-09 36.0 5.5 1.7e-05 24.8 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX77838.1 - 8.5e-09 35.6 1.2 9.5e-05 22.6 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77838.1 - 2.9e-06 26.8 4.5 0.00025 20.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KXX77838.1 - 6.7e-05 23.2 1.2 2.2 8.8 0.0 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77838.1 - 0.0007 19.5 3.9 0.026 14.7 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat Esterase_phd PF10503.4 KXX77840.1 - 1e-22 80.5 0.1 1.3e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX77840.1 - 1.3e-12 47.3 0.1 1.9e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX77840.1 - 4.2e-06 26.5 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX77840.1 - 0.00014 21.7 0.2 0.0003 20.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX77840.1 - 0.001 18.7 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KXX77840.1 - 0.0034 16.9 0.1 0.0062 16.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KXX77840.1 - 0.0046 16.4 0.3 0.008 15.6 0.2 1.5 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 KXX77840.1 - 0.017 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 KXX77840.1 - 0.033 13.4 0.1 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KXX77840.1 - 0.052 12.9 0.1 0.21 11.0 0.1 2.0 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.23 KXX77840.1 - 0.073 11.7 0.1 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family AXE1 PF05448.7 KXX77840.1 - 0.16 10.3 0.1 0.38 9.2 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PDZ_1 PF12812.2 KXX77841.1 - 5.8e-55 183.1 0.0 2.6e-34 116.9 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KXX77841.1 - 9e-16 57.9 0.0 1.5e-13 50.7 0.0 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KXX77841.1 - 5.9e-14 51.7 1.1 2.3e-05 24.1 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KXX77841.1 - 4.7e-08 33.0 0.0 0.0045 17.1 0.0 4.0 4 0 0 4 4 4 1 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KXX77841.1 - 0.00011 21.8 0.0 0.00035 20.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 KXX77841.1 - 0.076 12.8 0.2 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 KXX77841.1 - 0.14 11.5 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 KXX77841.1 - 0.21 9.9 0.2 0.71 8.2 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.11 KXX77841.1 - 0.53 9.5 0.4 0.82 8.9 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) ADH_zinc_N PF00107.21 KXX77843.1 - 3.5e-18 65.4 0.2 5.9e-18 64.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX77843.1 - 1e-09 39.3 0.2 2.5e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX77843.1 - 0.0021 17.7 0.0 0.0067 16.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_S3 PF00944.14 KXX77844.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphavirus core protein Ras PF00071.17 KXX77845.1 - 2.8e-54 182.8 0.9 9.7e-54 181.1 0.6 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KXX77845.1 - 6e-19 68.7 0.0 8.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX77845.1 - 2.7e-09 36.5 0.1 3.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX77845.1 - 1.3e-07 31.1 0.5 7.1e-07 28.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX77845.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KXX77845.1 - 0.0073 15.4 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KXX77845.1 - 0.073 12.4 0.5 0.78 9.1 0.1 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein DUF258 PF03193.11 KXX77845.1 - 0.099 11.8 0.2 0.18 11.0 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KXX77845.1 - 0.3 10.5 2.5 2.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.19 KXX77846.1 - 3.9e-30 104.1 0.0 1.2e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 KXX77847.1 - 5.5e-11 42.4 0.0 6.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein YukC PF10140.4 KXX77847.1 - 0.087 11.3 0.7 1.5 7.3 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Csm1 PF12539.3 KXX77847.1 - 0.12 12.9 0.6 0.21 12.0 0.3 1.5 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 ParA PF10609.4 KXX77848.1 - 1.1e-34 118.1 0.0 2e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KXX77848.1 - 6.4e-15 55.0 0.0 9.3e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KXX77848.1 - 4.1e-06 26.7 0.0 1.2e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KXX77848.1 - 1.4e-05 24.2 1.0 0.00037 19.6 0.4 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KXX77848.1 - 0.00014 21.3 0.1 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 KXX77848.1 - 0.00019 20.6 0.0 0.00042 19.4 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KXX77848.1 - 0.00073 19.1 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KXX77848.1 - 0.002 17.3 0.1 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 KXX77848.1 - 0.0048 16.4 0.1 0.0075 15.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX77848.1 - 0.0054 16.4 0.4 0.077 12.7 0.1 2.6 3 0 0 3 3 3 1 Part of AAA domain SRP54 PF00448.17 KXX77848.1 - 0.0096 15.3 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KXX77848.1 - 0.022 14.8 0.1 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KXX77848.1 - 0.024 13.8 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 KXX77848.1 - 0.026 13.3 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.17 KXX77848.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.1 KXX77848.1 - 0.045 13.7 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KXX77848.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KXX77848.1 - 0.053 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KXX77848.1 - 0.07 13.0 0.1 0.48 10.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.4 KXX77848.1 - 0.07 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KXX77848.1 - 0.079 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KXX77848.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain YhjQ PF06564.7 KXX77848.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein AAA_14 PF13173.1 KXX77848.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.1 KXX77849.1 - 4.3e-43 146.9 0.4 4.3e-43 146.9 0.3 2.7 3 1 1 4 4 4 1 Extracellular mutant protein 11 SRP54 PF00448.17 KXX77850.1 - 2.2e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KXX77850.1 - 5.2e-06 27.2 0.0 3.1e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX77850.1 - 9.5e-05 22.4 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 KXX77850.1 - 0.0001 21.1 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein PRK PF00485.13 KXX77850.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KXX77850.1 - 0.00027 21.2 0.2 0.0017 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX77850.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KXX77850.1 - 0.00084 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KXX77850.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 KXX77850.1 - 0.0017 17.3 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 KXX77850.1 - 0.002 18.2 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KXX77850.1 - 0.0021 17.6 0.1 0.0072 15.9 0.1 1.8 2 1 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KXX77850.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KXX77850.1 - 0.0039 16.9 0.0 0.0087 15.7 0.0 1.6 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KXX77850.1 - 0.0048 16.7 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KXX77850.1 - 0.0054 16.6 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KXX77850.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KXX77850.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 KXX77850.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.12 KXX77850.1 - 0.021 14.1 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 KXX77850.1 - 0.032 13.9 0.2 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KXX77850.1 - 0.04 13.8 0.1 0.082 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain LpxK PF02606.9 KXX77850.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_5 PF07728.9 KXX77850.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KXX77850.1 - 0.056 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KXX77850.1 - 0.064 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 KXX77850.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KXX77850.1 - 0.077 12.7 0.5 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KXX77850.1 - 0.091 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.10 KXX77850.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase KTI12 PF08433.5 KXX77850.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 KXX77850.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3644 PF12358.3 KXX77850.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) DUF258 PF03193.11 KXX77850.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 adh_short PF00106.20 KXX77851.1 - 2.6e-64 216.1 7.3 2.2e-32 112.2 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KXX77851.1 - 2.4e-32 112.0 2.2 5.5e-15 55.4 0.1 2.7 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 KXX77851.1 - 3.7e-32 110.2 0.0 7.2e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KXX77851.1 - 4.5e-11 42.6 0.0 2e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 KXX77851.1 - 7.4e-05 22.2 4.2 0.0079 15.6 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KXX77851.1 - 0.00052 19.1 1.0 0.012 14.7 0.3 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 KXX77851.1 - 0.044 14.0 0.6 7 6.9 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 KXX77851.1 - 1.4 8.5 6.5 3.1 7.3 0.7 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF500 PF04366.7 KXX77852.1 - 3.9e-34 116.8 0.0 7.2e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Bacteriocin_IId PF09221.5 KXX77852.1 - 1 9.3 0.0 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like LRR_4 PF12799.2 KXX77853.1 - 0.011 15.3 0.7 5.4 6.7 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Mit_KHE1 PF10173.4 KXX77855.1 - 5.6e-67 225.2 1.5 7.7e-67 224.7 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Cullin PF00888.17 KXX77857.1 - 2.2e-205 683.6 8.9 3.6e-205 682.9 6.2 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KXX77857.1 - 6.2e-27 93.2 6.2 6.2e-27 93.2 4.3 3.1 4 0 0 4 4 4 1 Cullin protein neddylation domain WGG PF10273.4 KXX77857.1 - 0.81 9.8 5.7 7.2 6.7 0.0 4.0 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 G-alpha PF00503.15 KXX77858.1 - 6.4e-124 413.5 0.5 7.6e-124 413.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KXX77858.1 - 1.5e-15 56.8 0.3 4.4e-10 39.0 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX77858.1 - 0.0001 21.5 0.2 0.076 12.1 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KXX77858.1 - 0.0017 18.8 0.1 0.96 9.9 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KXX77858.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 KXX77859.1 - 0 1071.1 0.0 0 1070.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 KXX77859.1 - 0.034 13.8 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Pkinase PF00069.20 KXX77860.1 - 9.8e-73 244.4 0.0 1.2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77860.1 - 8.2e-32 110.2 0.0 1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KXX77860.1 - 1.4e-05 24.3 0.0 5.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KXX77860.1 - 0.00025 20.1 0.0 0.018 14.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KXX77860.1 - 0.00046 19.9 0.1 0.0012 18.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KXX77860.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 KXX77861.1 - 1e-145 484.9 0.0 1.3e-145 484.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KXX77861.1 - 5.5e-07 29.1 0.1 5.6e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KXX77861.1 - 1.5e-06 27.8 0.0 0.00055 19.6 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis KH_1 PF00013.24 KXX77862.1 - 0.006 16.1 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 KXX77862.1 - 0.037 13.6 0.1 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 KH domain Pfg27 PF09216.5 KXX77862.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Pfg27 Ribosomal_60s PF00428.14 KXX77862.1 - 0.78 10.1 6.8 1.5 9.2 4.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein GATA PF00320.22 KXX77863.1 - 4.9e-15 54.5 2.7 8.6e-15 53.8 1.9 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF342 PF03961.8 KXX77863.1 - 0.0033 15.9 5.1 0.0046 15.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) TF_Zn_Ribbon PF08271.7 KXX77863.1 - 0.014 14.7 0.3 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3824 PF12868.2 KXX77863.1 - 0.071 14.0 0.6 0.071 14.0 0.4 2.2 2 1 0 2 2 1 0 Domain of unknwon function (DUF3824) DUF3584 PF12128.3 KXX77863.1 - 0.095 10.0 16.2 0.13 9.5 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.7 KXX77863.1 - 0.17 9.6 15.3 0.24 9.1 10.6 1.1 1 0 0 1 1 1 0 HOOK protein DUF2051 PF09738.4 KXX77863.1 - 0.2 10.9 14.9 0.7 9.1 10.2 1.8 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF4164 PF13747.1 KXX77863.1 - 0.22 11.6 14.4 0.43 10.7 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IncA PF04156.9 KXX77863.1 - 0.26 10.8 13.6 0.47 10.0 9.5 1.4 1 0 0 1 1 1 0 IncA protein Tho2 PF11262.3 KXX77863.1 - 0.31 10.0 6.3 0.47 9.4 4.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Macoilin PF09726.4 KXX77863.1 - 0.4 8.9 7.4 0.48 8.6 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4613 PF15390.1 KXX77863.1 - 0.57 8.2 6.4 0.73 7.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fmp27_WPPW PF10359.4 KXX77863.1 - 0.92 7.8 10.6 1.4 7.2 7.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PilJ PF13675.1 KXX77863.1 - 1.1 9.5 10.8 1.3 9.3 5.1 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-F_leu_zip PF10473.4 KXX77863.1 - 1.5 8.7 27.4 0.44 10.3 5.3 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 KXX77863.1 - 2.5 8.3 19.5 3.4 7.9 3.5 2.6 2 1 1 3 3 3 0 Striatin family V_ATPase_I PF01496.14 KXX77863.1 - 3.1 5.5 8.4 4.1 5.1 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KXX77863.1 - 5.1 6.0 16.9 7.6 5.4 11.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 KXX77863.1 - 6.5 6.1 9.0 13 5.1 5.9 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like INCENP_ARK-bind PF03941.10 KXX77864.1 - 3.7e-19 68.3 0.2 3.7e-19 68.3 0.1 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region IF-2B PF01008.12 KXX77864.1 - 1.3 7.9 6.5 0.079 11.9 0.1 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family Ycf1 PF05758.7 KXX77864.1 - 4.6 4.8 21.7 1.9 6.1 5.2 2.2 2 0 0 2 2 2 0 Ycf1 DnaJ PF00226.26 KXX77865.1 - 1.5e-19 69.4 0.5 1.5e-19 69.4 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain Snf7 PF03357.16 KXX77866.1 - 3.6e-18 65.5 14.8 5.6e-18 64.9 10.2 1.3 1 0 0 1 1 1 1 Snf7 Cas_DxTHG PF09455.5 KXX77866.1 - 0.2 10.7 0.5 0.3 10.2 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family SPOB_a PF14689.1 KXX77866.1 - 0.28 10.7 1.6 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Phage_int_SAM_1 PF02899.12 KXX77866.1 - 0.31 11.2 3.4 0.8 9.9 0.8 2.8 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain MutS_III PF05192.13 KXX77866.1 - 4.1 7.1 8.6 15 5.2 5.5 2.1 1 1 1 2 2 2 0 MutS domain III SAP PF02037.22 KXX77867.1 - 3.4e-07 29.6 0.1 5.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 KXX77867.1 - 8.6e-07 28.5 14.1 8.6e-07 28.5 9.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX77867.1 - 1.6e-06 28.0 15.0 1.6e-06 28.0 10.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX77867.1 - 4.6e-06 26.2 11.5 4.6e-06 26.2 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX77867.1 - 9.1e-06 25.3 13.4 9.1e-06 25.3 9.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KXX77867.1 - 2.8e-05 23.8 13.9 2.8e-05 23.8 9.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 KXX77867.1 - 2.9e-05 23.7 6.3 5.7e-05 22.8 3.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KXX77867.1 - 0.00033 20.2 6.1 0.00033 20.2 4.2 2.3 2 1 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 KXX77867.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 KXX77867.1 - 0.0014 18.4 13.6 0.0014 18.4 9.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KXX77867.1 - 0.014 14.9 4.7 0.014 14.9 3.2 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KXX77867.1 - 0.014 15.4 6.0 0.014 15.4 4.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger Mob_synth_C PF06463.8 KXX77867.1 - 0.13 11.8 3.1 0.34 10.6 2.1 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-P11 PF03854.9 KXX77867.1 - 9.1 5.8 15.4 3 7.3 6.8 2.3 2 0 0 2 2 2 0 P-11 zinc finger Tyr_Deacylase PF02580.11 KXX77868.1 - 2.8e-46 157.1 0.1 3.2e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 KXX77869.1 - 2.7e-99 331.1 25.3 2.7e-99 331.1 17.6 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KXX77869.1 - 3.1e-41 140.4 10.1 3.1e-41 140.4 7.0 2.3 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 KXX77869.1 - 2.7e-05 24.4 9.6 0.0005 20.3 0.1 2.6 2 0 0 2 2 2 1 Snapin/Pallidin DUF2373 PF10180.4 KXX77869.1 - 0.003 17.0 2.5 0.007 15.8 1.8 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KXX77869.1 - 0.011 15.6 11.7 0.017 15.0 1.1 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sec5 PF15469.1 KXX77869.1 - 0.014 15.0 12.4 0.15 11.7 2.0 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF1192 PF06698.6 KXX77869.1 - 0.017 14.9 2.9 0.017 14.9 2.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 KXX77869.1 - 0.035 14.1 0.4 0.035 14.1 0.3 2.8 2 1 0 2 2 1 0 Osmosensory transporter coiled coil Poty_PP PF08440.5 KXX77869.1 - 0.11 11.5 5.5 0.033 13.2 1.4 1.8 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 KXX77869.1 - 0.32 11.0 11.3 0.093 12.7 4.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein CorA PF01544.13 KXX77869.1 - 2.5 7.0 6.9 0.59 9.1 0.6 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Pex14_N PF04695.8 KXX77870.1 - 0.11 12.5 3.7 0.19 11.7 2.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CFEM PF05730.6 KXX77870.1 - 1.9 8.3 13.2 10 6.0 9.0 2.3 1 1 0 1 1 1 0 CFEM domain RAP1 PF07218.6 KXX77870.1 - 3.9 5.4 6.3 4.7 5.1 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.7 KXX77870.1 - 6.8 4.8 5.9 11 4.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-C3HC4_2 PF13923.1 KXX77871.1 - 8.6e-09 35.2 7.8 1.5e-08 34.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX77871.1 - 4.9e-08 32.6 6.2 8.4e-08 31.9 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX77871.1 - 2.2e-07 30.4 5.4 3.6e-07 29.7 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX77871.1 - 4.6e-07 29.3 6.4 8.3e-07 28.5 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX77871.1 - 3.8e-06 26.5 4.9 6.9e-06 25.6 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX77871.1 - 9.1e-06 25.4 6.1 4.8e-05 23.1 4.3 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KXX77871.1 - 0.0012 18.5 6.3 0.0029 17.2 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KXX77871.1 - 0.11 12.0 8.6 0.91 9.0 6.2 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger SOBP PF15279.1 KXX77871.1 - 0.14 12.4 3.9 1.1 9.5 1.3 2.5 3 0 0 3 3 3 0 Sine oculis-binding protein TerY-C PF15616.1 KXX77871.1 - 0.18 11.7 3.3 0.68 9.8 2.3 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.2 KXX77871.1 - 0.35 11.0 4.6 1 9.5 3.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KXX77871.1 - 1.2 9.1 4.2 3 7.8 2.9 1.7 1 1 0 1 1 1 0 FYVE zinc finger 2OG-FeII_Oxy_3 PF13640.1 KXX77873.1 - 0.054 13.9 0.0 0.092 13.2 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.1 KXX77874.1 - 7.6e-22 78.0 0.1 2e-19 70.1 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KXX77874.1 - 4.2e-06 26.3 0.0 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin T2SE_Nter PF05157.10 KXX77874.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Ino80_Iec3 PF14612.1 KXX77875.1 - 2e-61 208.0 4.6 1.3e-32 113.7 0.6 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling AAA PF00004.24 KXX77876.1 - 9.1e-20 71.2 0.0 1.7e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX77876.1 - 2.9e-05 23.7 0.0 7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX77876.1 - 0.00019 21.1 0.1 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KXX77876.1 - 0.00029 20.8 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KXX77876.1 - 0.00042 21.1 0.0 0.0059 17.4 0.0 2.8 2 1 1 3 3 2 1 AAA domain Zot PF05707.7 KXX77876.1 - 0.00046 19.7 0.1 0.011 15.1 0.0 2.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_2 PF07724.9 KXX77876.1 - 0.00071 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KXX77876.1 - 0.0015 18.6 0.1 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX77876.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KXX77876.1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.1 KXX77876.1 - 0.0092 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KXX77876.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX77876.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KXX77876.1 - 0.021 13.9 0.1 0.046 12.8 0.1 1.5 1 1 0 1 1 1 0 KaiC AAA_18 PF13238.1 KXX77876.1 - 0.023 14.9 0.0 0.076 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX77876.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KXX77876.1 - 0.1 12.4 0.0 7.6 6.4 0.0 2.3 1 1 1 2 2 2 0 Torsin Sigma54_activat PF00158.21 KXX77876.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 KXX77876.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Lzipper-MIP1 PF14389.1 KXX77877.1 - 0.0051 16.8 3.8 0.55 10.3 0.1 3.3 3 0 0 3 3 3 2 Leucine-zipper of ternary complex factor MIP1 DUF244 PF03112.9 KXX77877.1 - 0.067 12.7 0.9 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Spc24 PF08286.6 KXX77877.1 - 3.1 7.5 11.4 0.46 10.2 1.2 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 RasGAP PF00616.14 KXX77878.1 - 1.7e-45 155.1 0.0 2.7e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KXX77878.1 - 4.6e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pro_isomerase PF00160.16 KXX77879.1 - 1.6e-46 158.3 0.2 2.4e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KXX77879.1 - 1.1e-08 34.5 7.0 3e-05 23.5 0.3 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KXX77879.1 - 1.5e-06 27.6 3.2 0.00028 20.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX77879.1 - 0.00014 21.2 0.9 0.00044 19.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77879.1 - 0.0021 17.9 1.5 0.0063 16.4 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX77879.1 - 0.0044 17.5 3.6 0.0082 16.6 0.8 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX77879.1 - 0.0044 16.7 1.0 0.011 15.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77879.1 - 0.0049 17.4 2.2 0.0049 17.4 1.5 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX77879.1 - 0.012 16.0 1.2 0.052 14.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX77879.1 - 0.028 14.7 2.6 0.068 13.5 1.6 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KXX77879.1 - 0.04 13.7 0.4 0.09 12.6 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NmrA PF05368.8 KXX77880.1 - 1.5e-48 165.0 0.4 1.8e-48 164.8 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX77880.1 - 1.6e-12 47.8 0.5 2.2e-12 47.3 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KXX77880.1 - 0.024 14.6 0.1 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 KXX77880.1 - 0.069 11.8 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4157 PF13699.1 KXX77880.1 - 0.091 12.9 0.3 0.091 12.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) HET PF06985.6 KXX77881.1 - 9.2e-24 84.1 0.0 1.8e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.9 KXX77882.1 - 1.2e-58 198.5 0.0 1.5e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX77882.1 - 1.2e-10 40.8 12.2 4.2e-10 39.1 8.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain NAD_binding_6 PF08030.7 KXX77885.1 - 2.4e-21 76.2 0.0 4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KXX77885.1 - 7.1e-14 51.9 6.8 7.1e-14 51.9 4.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KXX77885.1 - 1.3e-11 44.3 0.0 2.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KXX77885.1 - 0.075 13.6 0.0 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FixP_N PF14715.1 KXX77885.1 - 0.083 12.2 0.8 12 5.4 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF4405 PF14358.1 KXX77885.1 - 1 9.5 13.3 0.066 13.3 3.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Iso_dh PF00180.15 KXX77886.1 - 1.4e-69 234.7 0.0 1.7e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2_4 PF13894.1 KXX77887.1 - 0.24 11.8 0.1 0.24 11.8 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX77887.1 - 0.26 11.7 0.2 0.26 11.7 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type UPF0160 PF03690.8 KXX77888.1 - 6.3e-122 406.9 0.0 7.1e-122 406.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Nop10p PF04135.7 KXX77888.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family DUF1793 PF08760.6 KXX77889.1 - 2.1e-61 206.7 0.0 3.6e-61 205.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Endosulfine PF04667.12 KXX77890.1 - 5.4e-21 74.3 0.8 1.1e-20 73.3 0.0 1.8 2 1 1 3 3 3 1 cAMP-regulated phosphoprotein/endosulfine conserved region DivIC PF04977.10 KXX77891.1 - 0.005 16.2 0.4 0.014 14.8 0.3 1.7 1 0 0 1 1 1 1 Septum formation initiator IncA PF04156.9 KXX77891.1 - 0.013 15.0 0.3 0.036 13.6 0.2 1.7 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KXX77891.1 - 1.5 9.2 5.9 0.51 10.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 KXX77891.1 - 6.8 6.6 10.5 0.56 10.0 1.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper PGAP1 PF07819.8 KXX77892.1 - 3.3e-09 36.6 0.0 6.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KXX77892.1 - 2.1e-08 34.3 0.4 3.3e-08 33.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX77892.1 - 1.2e-06 27.9 0.1 3.2e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 KXX77892.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KXX77892.1 - 0.00079 19.1 0.1 0.0012 18.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KXX77892.1 - 0.0043 16.3 0.0 0.044 13.0 0.0 2.2 2 1 0 2 2 2 1 Lipase (class 2) Thioesterase PF00975.15 KXX77892.1 - 0.0099 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KXX77892.1 - 0.015 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KXX77892.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase DUF900 PF05990.7 KXX77892.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Arrestin_N PF00339.24 KXX77893.1 - 1.1e-14 54.5 0.0 2.5e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KXX77893.1 - 1.5e-05 25.1 0.0 0.001 19.1 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MRP_L53 PF10780.4 KXX77894.1 - 3.4e-20 71.7 0.3 5.3e-20 71.1 0.2 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 KXX77895.1 - 5e-16 58.1 0.7 1.4e-15 56.7 0.1 2.0 2 0 0 2 2 2 1 Sec20 ARA70 PF12489.3 KXX77895.1 - 0.014 15.3 0.7 0.059 13.3 0.3 2.1 2 0 0 2 2 2 0 Nuclear coactivator WD40 PF00400.27 KXX77897.1 - 2.2e-07 30.5 5.6 0.057 13.3 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2583 PF10762.4 KXX77897.1 - 0.037 14.1 0.6 0.17 12.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) ArfGap PF01412.13 KXX77898.1 - 3.4e-35 120.3 0.5 1e-34 118.7 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KXX77898.1 - 7.1e-13 48.6 0.1 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PilJ PF13675.1 KXX77898.1 - 0.032 14.5 0.5 0.032 14.5 0.3 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PH_9 PF15410.1 KXX77898.1 - 2.9 8.0 5.5 1.2 9.3 0.6 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 KXX77899.1 - 2.9e-76 256.0 0.0 3.8e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX77899.1 - 6.5e-37 126.9 0.0 9e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KXX77899.1 - 2.1e-15 56.5 0.1 4.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KXX77899.1 - 4.6e-09 35.6 0.0 1e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KXX77899.1 - 0.017 14.4 0.1 0.073 12.4 0.0 2.0 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KXX77899.1 - 0.017 13.9 0.1 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KXX77899.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyrophosphatase PF00719.14 KXX77900.1 - 5e-51 172.2 0.2 6.6e-51 171.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Membr_traf_MHD PF10540.4 KXX77901.1 - 2.1e-23 82.6 0.1 5.5e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KXX77901.1 - 1.9e-17 62.8 0.0 4.5e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KXX77901.1 - 0.0041 15.4 0.1 0.0083 14.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF810) ADK PF00406.17 KXX77902.1 - 3.6e-44 150.2 0.0 5.2e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KXX77902.1 - 3.2e-07 30.7 0.0 5.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX77902.1 - 5.5e-07 30.4 0.0 8.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX77902.1 - 6.4e-06 26.0 1.0 1.5e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KXX77902.1 - 0.0029 17.0 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Mito_fiss_reg PF05308.6 KXX77902.1 - 0.19 11.0 4.1 0.66 9.3 2.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF202 PF02656.10 KXX77903.1 - 0.011 15.9 5.9 0.39 10.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MARVEL PF01284.18 KXX77903.1 - 0.025 14.4 5.9 0.13 12.0 3.3 2.2 2 0 0 2 2 2 0 Membrane-associating domain Tetraspannin PF00335.15 KXX77903.1 - 0.14 11.3 9.5 0.29 10.3 6.6 1.5 1 1 0 1 1 1 0 Tetraspanin family TctB PF07331.6 KXX77903.1 - 0.16 11.6 3.6 0.11 12.0 1.0 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2721 PF11026.3 KXX77903.1 - 0.64 9.6 5.5 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Vpu PF00558.14 KXX77903.1 - 1.3 8.6 6.8 2.4 7.7 1.2 2.4 2 0 0 2 2 2 0 Vpu protein DUF2207 PF09972.4 KXX77903.1 - 1.5 7.3 3.7 8.8 4.7 0.1 2.5 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) TPR_11 PF13414.1 KXX77904.1 - 6e-11 41.8 0.1 2.5e-10 39.8 0.0 2.0 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KXX77904.1 - 2.5e-06 26.9 1.9 0.098 12.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX77904.1 - 2e-05 24.0 1.5 0.0046 16.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX77904.1 - 8.9e-05 22.5 0.6 0.00024 21.1 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KXX77904.1 - 0.006 16.9 0.1 0.13 12.6 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX77904.1 - 0.0068 17.0 3.4 0.13 12.9 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX77904.1 - 0.025 14.5 0.2 0.25 11.3 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat PCI PF01399.22 KXX77905.1 - 6.7e-15 55.2 0.2 1.3e-13 51.1 0.1 2.5 2 0 0 2 2 2 1 PCI domain Med2 PF11214.3 KXX77905.1 - 0.0065 16.4 0.1 0.023 14.7 0.1 2.0 1 0 0 1 1 1 1 Mediator complex subunit 2 Nucleopor_Nup85 PF07575.8 KXX77905.1 - 0.0077 14.4 0.1 0.012 13.8 0.0 1.3 1 0 0 1 1 1 1 Nup85 Nucleoporin BCAS2 PF05700.6 KXX77905.1 - 0.016 14.7 0.6 0.016 14.7 0.4 1.8 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3939 PF13075.1 KXX77905.1 - 0.084 12.6 0.6 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) DUF1993 PF09351.5 KXX77905.1 - 0.16 11.8 1.3 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) GTP_EFTU PF00009.22 KXX77906.1 - 4.6e-38 130.5 0.1 7.9e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KXX77906.1 - 2.4e-37 126.8 0.3 5.1e-37 125.8 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KXX77906.1 - 4.1e-10 39.6 0.2 9.2e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KXX77906.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX77906.1 - 0.12 12.2 0.3 0.39 10.5 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Connexin_CCC PF10582.4 KXX77906.1 - 0.15 11.8 0.4 0.39 10.5 0.3 1.6 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain DUF2452 PF10504.4 KXX77907.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) 14-3-3 PF00244.15 KXX77908.1 - 2.7e-112 373.6 1.8 3.7e-112 373.1 1.2 1.2 1 0 0 1 1 1 1 14-3-3 protein Mito_carr PF00153.22 KXX77909.1 - 1.4e-61 204.1 0.1 1.9e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KXX77910.1 - 8.2e-34 116.2 7.2 8.2e-34 116.2 5.0 1.4 1 1 1 2 2 2 1 TspO/MBR family IATP PF04568.7 KXX77911.1 - 1.1e-21 76.7 0.1 1.3e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NinG PF05766.7 KXX77911.1 - 0.042 13.5 0.2 0.048 13.4 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF489 PF04356.7 KXX77911.1 - 0.1 12.1 0.3 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DivIC PF04977.10 KXX77911.1 - 0.43 10.1 3.4 0.58 9.6 2.4 1.2 1 0 0 1 1 1 0 Septum formation initiator Nsp1_C PF05064.8 KXX77912.1 - 1.3e-42 144.1 2.9 2.9e-42 143.0 2.0 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 KXX77912.1 - 0.0012 18.0 2.3 0.57 9.3 0.0 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Nucleoporin_FG PF13634.1 KXX77912.1 - 0.0099 16.0 42.0 0.0099 16.0 29.1 6.3 2 1 4 6 6 5 4 Nucleoporin FG repeat region Myosin_tail_1 PF01576.14 KXX77912.1 - 0.013 13.2 8.8 0.11 10.2 6.1 1.8 1 1 0 1 1 1 0 Myosin tail MscS_porin PF12795.2 KXX77912.1 - 0.027 13.7 9.3 0.16 11.2 1.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 KXX77912.1 - 0.029 14.1 3.0 4.2 7.2 0.4 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KXX77912.1 - 0.09 12.3 4.1 0.25 10.9 2.9 1.7 1 1 0 1 1 1 0 IncA protein EzrA PF06160.7 KXX77912.1 - 0.092 10.9 6.8 0.43 8.6 3.9 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GAT PF03127.9 KXX77912.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 GAT domain APG6 PF04111.7 KXX77912.1 - 0.19 10.7 6.3 0.1 11.5 2.7 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Bul1_C PF04426.7 KXX77912.1 - 0.36 9.9 1.5 0.61 9.2 1.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus DUF972 PF06156.8 KXX77912.1 - 0.85 9.9 3.0 4 7.8 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KXX77912.1 - 1.7 7.0 8.0 3.6 5.9 5.6 1.4 1 1 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 KXX77912.1 - 2.5 7.8 8.9 0.98 9.2 0.7 2.9 2 1 0 3 3 3 0 Prefoldin subunit ApoLp-III PF07464.6 KXX77912.1 - 2.8 7.9 8.7 0.55 10.2 3.2 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) zf-CSL PF05207.8 KXX77913.1 - 1.5e-15 56.3 0.0 2.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KXX77913.1 - 0.024 14.3 8.0 0.069 12.8 4.9 2.4 2 1 0 2 2 2 0 DnaJ domain PAT1 PF09770.4 KXX77913.1 - 0.73 7.9 34.8 0.89 7.7 24.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 KXX77914.1 - 1.3e-27 96.7 4.0 3.2e-27 95.4 2.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX77914.1 - 6.3e-10 39.0 6.2 1.5e-08 34.5 4.2 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX77914.1 - 8e-10 38.8 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX77914.1 - 5.8e-09 36.2 0.4 1.9e-08 34.5 0.2 2.0 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KXX77914.1 - 2.3e-06 27.2 0.2 7.2e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KXX77914.1 - 0.00056 18.8 0.0 0.00088 18.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KXX77914.1 - 0.0019 16.9 0.1 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0146 PF03686.8 KXX77914.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.13 KXX77914.1 - 0.04 13.5 0.9 0.11 12.1 0.3 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FtsJ PF01728.14 KXX77914.1 - 0.04 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TrkA_N PF02254.13 KXX77914.1 - 0.055 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 KXX77914.1 - 0.12 11.6 0.3 0.2 10.8 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 KXX77914.1 - 2.3 7.0 4.0 0.57 9.0 0.3 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.14 KXX77915.1 - 1.4e-58 198.6 0.0 1.9e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KXX77915.1 - 1.5e-33 115.7 0.0 2.9e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Ank_2 PF12796.2 KXX77916.1 - 1.8e-26 92.2 0.2 1.8e-18 66.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77916.1 - 1.2e-21 75.3 0.9 1.4e-07 30.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat HET PF06985.6 KXX77916.1 - 2.4e-21 76.3 2.0 8e-17 61.6 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 KXX77916.1 - 3.4e-15 55.7 0.4 1e-09 38.3 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX77916.1 - 5.5e-15 55.4 0.2 2.4e-10 40.6 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX77916.1 - 1.5e-10 40.2 0.0 0.001 19.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DivIC PF04977.10 KXX77916.1 - 0.026 13.9 1.6 0.059 12.8 1.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CCDC155 PF14662.1 KXX77916.1 - 0.051 13.1 7.1 0.086 12.4 4.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 KXX77916.1 - 0.056 13.3 8.4 0.11 12.3 5.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 KXX77916.1 - 0.15 10.9 5.7 0.23 10.3 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 KXX77916.1 - 0.15 10.4 2.7 0.22 9.9 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KXX77916.1 - 0.21 10.5 5.2 0.31 10.0 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 KXX77916.1 - 0.22 11.3 1.7 0.56 10.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KXX77916.1 - 0.43 10.9 6.0 1.1 9.5 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KXX77916.1 - 0.53 8.8 5.4 0.82 8.2 3.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.1 KXX77916.1 - 0.62 9.7 8.0 2.5 7.7 4.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.14 KXX77916.1 - 1.6 6.4 3.9 2.3 5.9 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.1 KXX77916.1 - 4.3 7.1 5.6 8 6.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) F-box PF00646.28 KXX77917.1 - 5.1e-07 29.1 1.9 1.2e-06 28.0 1.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX77917.1 - 1.4e-06 27.9 0.6 4.9e-06 26.1 0.4 2.0 1 0 0 1 1 1 1 F-box-like Indigoidine_A PF04227.7 KXX77919.1 - 3.1e-105 351.6 0.4 4.9e-105 350.9 0.1 1.5 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.19 KXX77919.1 - 2.5e-22 79.3 0.0 2.6e-21 76.0 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DNA_mis_repair PF01119.14 KXX77921.1 - 4e-34 116.6 0.1 6.4e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KXX77921.1 - 4.8e-13 48.9 0.0 9.1e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KXX77921.1 - 3.2e-11 42.9 0.0 6.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lon_C PF05362.8 KXX77922.1 - 8.6e-68 227.6 0.2 1.6e-67 226.8 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KXX77922.1 - 1.1e-23 83.8 0.0 3.1e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KXX77922.1 - 2.9e-22 79.3 0.0 5.5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KXX77922.1 - 1.4e-10 41.0 0.0 4.2e-10 39.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KXX77922.1 - 1.3e-07 31.1 0.0 2.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KXX77922.1 - 4.6e-06 26.7 1.6 1.1e-05 25.5 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 KXX77922.1 - 2e-05 25.3 0.0 7.4e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KXX77922.1 - 2.9e-05 23.6 0.0 8.8e-05 22.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KXX77922.1 - 3.5e-05 23.3 0.0 7.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KXX77922.1 - 0.00016 21.8 0.0 0.0034 17.5 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KXX77922.1 - 0.0002 21.3 0.0 0.00063 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KXX77922.1 - 0.00045 19.3 0.1 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KXX77922.1 - 0.0008 19.3 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KXX77922.1 - 0.00099 18.5 0.0 0.003 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX77922.1 - 0.001 18.7 0.4 0.0091 15.7 0.0 2.8 4 0 0 4 4 1 1 Part of AAA domain AAA_33 PF13671.1 KXX77922.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KXX77922.1 - 0.0013 17.5 0.4 0.0038 16.0 0.1 1.8 2 0 0 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 KXX77922.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KXX77922.1 - 0.022 15.0 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KXX77922.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KXX77922.1 - 0.034 13.8 0.0 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KXX77922.1 - 0.035 14.2 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KXX77922.1 - 0.04 13.4 0.1 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KXX77922.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KXX77922.1 - 0.062 12.4 0.1 0.15 11.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KXX77922.1 - 0.065 12.4 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KXX77922.1 - 0.069 12.8 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.1 KXX77922.1 - 0.07 13.4 2.6 0.21 11.8 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KXX77922.1 - 0.09 12.3 0.4 3.1 7.3 0.0 2.9 1 1 1 2 2 2 0 AAA domain AAA_PrkA PF08298.6 KXX77922.1 - 0.15 10.7 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain CCDC-167 PF15188.1 KXX77922.1 - 2.4 8.1 5.9 1.4 8.8 1.8 2.4 2 0 0 2 2 1 0 Coiled-coil domain-containing protein 167 FAD_binding_1 PF00667.15 KXX77924.1 - 1e-59 201.6 0.0 1.5e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KXX77924.1 - 3e-34 118.0 0.3 6.6e-34 116.9 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KXX77924.1 - 4.8e-21 75.3 0.1 4.1e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KXX77924.1 - 0.0097 15.9 0.1 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain MOR2-PAG1_N PF14222.1 KXX77925.1 - 4.3e-223 741.9 0.0 7.4e-223 741.2 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KXX77925.1 - 9.2e-97 323.8 1.7 2.7e-96 322.3 1.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KXX77925.1 - 2.2e-36 124.9 5.5 2.8e-15 55.0 0.0 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.2 KXX77925.1 - 6.3 6.6 8.2 2.9 7.7 0.0 4.1 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RIO1 PF01163.17 KXX77926.1 - 1.2e-40 138.8 0.1 3e-40 137.5 0.1 1.6 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KXX77926.1 - 4.9e-33 113.0 0.0 1e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KXX77926.1 - 1.4e-06 28.2 4.1 0.0016 18.2 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KXX77926.1 - 2.1e-06 26.9 0.1 0.0084 15.1 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.1 KXX77926.1 - 0.077 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sigma70_ner PF04546.8 KXX77926.1 - 2.3 7.7 13.1 4.5 6.8 9.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 KXX77926.1 - 4.2 7.8 14.9 8 6.9 10.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DCA16 PF15349.1 KXX77926.1 - 7.3 5.8 6.1 13 5.0 4.2 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 CDC45 PF02724.9 KXX77926.1 - 8.6 4.2 12.9 12 3.8 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 KXX77926.1 - 9.9 5.4 13.3 13 5.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RRM_1 PF00076.17 KXX77927.1 - 8.7e-26 89.3 0.0 1.8e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX77927.1 - 3.3e-16 59.0 0.0 1.2e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX77927.1 - 1.3e-08 34.5 0.1 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec1 PF00995.18 KXX77928.1 - 2.2e-133 445.8 0.0 2.6e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PC_rep PF01851.17 KXX77929.1 - 1.2e-24 85.0 17.9 6.1e-07 29.3 0.0 9.5 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KXX77929.1 - 3e-09 37.0 0.6 7.9e-05 22.8 0.1 3.9 3 0 0 3 3 3 2 HEAT repeats TPR_5 PF12688.2 KXX77929.1 - 0.061 13.3 0.4 6.2 6.8 0.0 3.2 2 1 1 3 3 3 0 Tetratrico peptide repeat HEAT PF02985.17 KXX77929.1 - 0.086 12.9 0.0 30 5.0 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KXX77929.1 - 0.091 13.2 0.7 6.3 7.4 0.0 3.8 2 1 2 4 4 4 0 HEAT-like repeat FAD_binding_3 PF01494.14 KXX77931.1 - 9.3e-18 64.3 0.2 1.1e-16 60.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX77931.1 - 1.6e-06 28.0 0.5 3.7e-06 26.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KXX77931.1 - 6.6e-05 21.8 0.0 0.00025 19.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KXX77931.1 - 0.00091 18.2 0.3 0.0014 17.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX77931.1 - 0.0044 17.3 0.4 0.022 15.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX77931.1 - 0.0047 16.8 1.4 0.011 15.5 0.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX77931.1 - 0.0083 15.0 0.4 0.022 13.6 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KXX77931.1 - 0.033 13.2 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 KXX77931.1 - 0.035 13.9 0.2 0.26 11.0 0.2 2.3 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 KXX77931.1 - 0.06 12.4 0.2 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KXX77931.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX77931.1 - 0.26 10.1 0.9 0.38 9.5 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transp_cyt_pur PF02133.10 KXX77932.1 - 1e-28 100.0 29.3 8.3e-28 97.1 20.3 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1418 PF07214.7 KXX77932.1 - 6.8 6.3 7.5 3.8 7.2 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) RibD_C PF01872.12 KXX77933.1 - 8.4e-31 107.1 0.0 1.1e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain DMAP_binding PF06464.6 KXX77933.1 - 0.11 13.0 3.7 0.18 12.4 2.6 1.2 1 0 0 1 1 1 0 DMAP1-binding Domain Secretin_N_2 PF07655.8 KXX77933.1 - 0.11 12.8 20.9 0.22 11.9 14.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Zip PF02535.17 KXX77933.1 - 0.3 10.0 3.1 0.41 9.5 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 KXX77933.1 - 0.75 9.8 5.6 1.1 9.2 3.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 KXX77933.1 - 6.9 4.7 8.8 8.7 4.3 6.1 1.1 1 0 0 1 1 1 0 Menin Npa1 PF11707.3 KXX77934.1 - 4.7e-86 288.7 0.0 7.9e-86 288.0 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Arm PF00514.18 KXX77934.1 - 0.02 14.7 0.6 0.068 13.0 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HET PF06985.6 KXX77936.1 - 4.6e-30 104.5 0.1 7.2e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPA_C PF08784.6 KXX77937.1 - 1.5e-16 60.6 0.4 4.7e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KXX77937.1 - 1.8e-07 30.9 0.1 4.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Acetyltransf_7 PF13508.1 KXX77938.1 - 6.8e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX77938.1 - 7.6e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KXX77938.1 - 5.3e-07 29.5 0.1 9.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX77938.1 - 0.00044 19.9 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KXX77938.1 - 0.00059 19.9 0.1 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KXX77938.1 - 0.03 14.1 0.0 0.086 12.7 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase NUDIX PF00293.23 KXX77939.1 - 1.9e-28 98.7 0.0 2.7e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.13 KXX77941.1 - 1e-55 187.8 28.0 1.4e-29 102.8 6.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KXX77941.1 - 2 8.2 37.1 0.017 14.9 7.7 4.2 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain GMC_oxred_N PF00732.14 KXX77942.1 - 1.3e-36 126.2 0.2 3.7e-35 121.5 0.2 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX77942.1 - 1.1e-24 87.3 0.0 2.1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX77942.1 - 0.00012 22.0 0.1 0.00012 22.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX77942.1 - 0.00017 21.7 0.2 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX77942.1 - 0.00034 20.5 0.0 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX77942.1 - 0.0019 17.1 0.2 0.0045 15.9 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX77942.1 - 0.0023 16.8 0.2 0.02 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fib_succ_major PF09603.5 KXX77942.1 - 0.0031 18.0 0.5 0.0065 16.9 0.3 1.4 1 0 0 1 1 1 1 Fibrobacter succinogenes major domain (Fib_succ_major) HI0933_like PF03486.9 KXX77942.1 - 0.013 13.9 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KXX77942.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX77942.1 - 0.068 12.2 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KXX77942.1 - 0.089 11.8 0.1 0.22 10.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family PEP_mutase PF13714.1 KXX77943.1 - 2.6e-57 193.8 2.2 2.9e-57 193.6 1.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ADH_zinc_N PF00107.21 KXX77943.1 - 0.053 13.0 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ACP PF06857.6 KXX77943.1 - 0.054 13.4 0.2 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) MGC-24 PF05283.6 KXX77945.1 - 0.0045 16.7 7.2 0.0051 16.6 5.0 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Sporozoite_P67 PF05642.6 KXX77945.1 - 0.41 8.4 11.0 0.51 8.1 7.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fungal_trans PF04082.13 KXX77947.1 - 8e-19 67.5 2.0 1.5e-18 66.6 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77947.1 - 5.2e-08 32.6 12.8 9.7e-08 31.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 KXX77948.1 - 6.3e-118 394.9 0.0 8.4e-118 394.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Transposase_1 PF01359.13 KXX77948.1 - 0.17 11.6 0.9 0.43 10.3 0.1 2.0 2 0 0 2 2 2 0 Transposase (partial DDE domain) ADH_zinc_N_2 PF13602.1 KXX77949.1 - 3.7e-23 82.8 0.3 1.3e-22 81.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX77949.1 - 4e-19 68.4 0.1 7.2e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KXX77949.1 - 0.0039 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KXX77949.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SKG6 PF08693.5 KXX77950.1 - 7e-07 28.4 0.6 3.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CBM_21 PF03370.8 KXX77951.1 - 4.3e-35 120.0 0.1 7.1e-35 119.3 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Med22 PF06179.7 KXX77952.1 - 9.1e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.15 KXX77953.1 - 1.5e-24 86.4 0.0 4.4e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase GMC_oxred_N PF00732.14 KXX77954.1 - 1.3e-62 211.5 0.0 1.7e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX77954.1 - 1.7e-34 119.1 0.0 3.4e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX77954.1 - 6.5e-07 28.5 0.0 0.0088 14.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX77954.1 - 0.00033 19.6 0.0 0.046 12.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX77954.1 - 0.0016 18.4 0.1 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX77954.1 - 0.0096 15.9 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX77954.1 - 0.068 13.0 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX77954.1 - 0.096 11.5 0.1 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KXX77954.1 - 0.18 11.5 0.5 0.95 9.2 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mid2 PF04478.7 KXX77955.1 - 0.0044 16.4 0.4 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KXX77955.1 - 0.053 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 KXX77955.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SKI PF01202.17 KXX77955.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase APG17 PF04108.7 KXX77956.1 - 2.9e-102 342.5 0.0 3.6e-102 342.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 IncA PF04156.9 KXX77956.1 - 0.026 14.1 1.4 0.049 13.2 0.4 1.8 1 1 0 1 1 1 0 IncA protein HALZ PF02183.13 KXX77956.1 - 0.039 13.6 0.1 2 8.2 0.0 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper V-SNARE PF05008.10 KXX77956.1 - 0.27 11.4 2.7 0.49 10.5 0.2 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus LOH1CR12 PF10158.4 KXX77956.1 - 0.85 9.4 5.7 40 4.0 0.1 3.5 2 1 1 3 3 3 0 Tumour suppressor protein RIO1 PF01163.17 KXX77957.1 - 1.2e-66 223.7 0.9 1.8e-66 223.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Adeno_E1A PF02703.9 KXX77957.1 - 0.0086 15.5 1.7 0.015 14.7 1.2 1.3 1 0 0 1 1 1 1 Early E1A protein DUF3464 PF11947.3 KXX77957.1 - 0.41 10.0 2.0 1 8.7 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ribonuc_L-PSP PF01042.16 KXX77958.1 - 5.5e-24 84.2 0.0 6.7e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_9 PF08021.6 KXX77958.1 - 0.012 15.5 0.0 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain MFS_1 PF07690.11 KXX77959.1 - 9.2e-52 175.8 31.8 9.2e-52 175.8 22.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX77959.1 - 3.1e-10 39.2 26.1 3.1e-09 35.9 18.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KXX77959.1 - 6.3e-05 21.2 2.3 6.3e-05 21.2 1.6 1.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 KXX77959.1 - 0.0026 16.0 1.2 0.0041 15.3 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMPIT PF07851.8 KXX77959.1 - 0.22 10.5 1.7 0.54 9.2 1.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein COesterase PF00135.23 KXX77960.1 - 1.5e-89 301.1 0.1 2.1e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX77960.1 - 0.0011 18.5 0.1 0.0053 16.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX77960.1 - 0.086 12.0 0.5 0.22 10.7 0.2 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF946 PF06101.6 KXX77964.1 - 5.3e-18 64.3 0.0 7.3e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Fil_haemagg_2 PF13332.1 KXX77964.1 - 0.00043 20.0 1.6 0.00075 19.3 1.1 1.3 1 0 0 1 1 1 1 Haemagluttinin repeat Binary_toxB PF03495.9 KXX77964.1 - 0.0033 16.1 2.3 0.0047 15.6 1.6 1.1 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA GAD-like PF08887.6 KXX77964.1 - 0.006 16.6 0.4 0.96 9.5 0.0 2.9 3 0 0 3 3 3 1 GAD-like domain Fungal_trans PF04082.13 KXX77965.1 - 1.7e-23 82.8 0.1 3.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX77965.1 - 2.1e-07 30.7 13.5 4.3e-07 29.7 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 KXX77965.1 - 0.027 14.1 1.1 0.053 13.2 0.7 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DDE_Tnp_1_7 PF13843.1 KXX77965.1 - 0.2 10.6 1.5 0.35 9.8 1.0 1.2 1 0 0 1 1 1 0 Transposase IS4 IL1_propep PF02394.11 KXX77965.1 - 0.27 11.6 1.3 0.51 10.7 0.9 1.4 1 0 0 1 1 1 0 Interleukin-1 propeptide Abhydrolase_3 PF07859.8 KXX77966.1 - 1.2e-08 34.7 1.7 6.2e-08 32.4 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KXX77966.1 - 2.4e-05 24.0 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX77966.1 - 6.2e-05 22.7 0.4 0.00018 21.3 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family PAE PF03283.8 KXX77966.1 - 0.2 10.2 0.0 0.35 9.4 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Ank_2 PF12796.2 KXX77967.1 - 2.6e-38 130.2 0.0 2.9e-21 75.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX77967.1 - 1.8e-22 77.9 0.2 2.3e-07 30.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KXX77967.1 - 1.3e-17 62.1 0.0 3.1e-05 23.7 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KXX77967.1 - 4.9e-15 55.5 0.1 3.9e-09 36.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 KXX77967.1 - 1.1e-10 41.4 0.2 3.2e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 KXX77967.1 - 1.6e-10 40.8 0.4 4.6e-05 23.5 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 KXX77967.1 - 6.3e-08 32.8 0.3 7.4e-07 29.3 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX77967.1 - 0.00018 21.6 0.0 0.00073 19.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain DUF676 PF05057.9 KXX77967.1 - 0.00057 19.2 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KXX77967.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KXX77967.1 - 0.0024 17.6 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family KAP_NTPase PF07693.9 KXX77967.1 - 0.0054 15.7 0.3 2.5 6.9 0.0 2.2 1 1 0 2 2 2 2 KAP family P-loop domain Abhydrolase_6 PF12697.2 KXX77967.1 - 0.0058 16.5 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_18 PF13238.1 KXX77967.1 - 0.031 14.5 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KXX77967.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KXX77967.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 KXX77967.1 - 0.06 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KXX77967.1 - 0.18 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Abhydrolase_3 PF07859.8 KXX77968.1 - 5.7e-36 124.0 0.0 7e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KXX77968.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 KXX77968.1 - 0.32 9.5 0.0 0.51 8.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Beta-lactamase PF00144.19 KXX77969.1 - 5.3e-40 137.4 0.1 6.5e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Aminotran_3 PF00202.16 KXX77970.1 - 4.2e-90 302.0 0.0 5.4e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pyridoxal_deC PF00282.14 KXX77971.1 - 1.4e-77 260.6 0.0 2e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KXX77971.1 - 8.9e-08 31.2 0.0 1.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KXX77971.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.6 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AIP3 PF03915.8 KXX77972.1 - 2.5e-165 550.5 11.3 3.5e-165 550.0 7.9 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 KXX77972.1 - 0.00062 19.1 0.2 0.00062 19.1 0.1 2.4 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain FliL PF03748.9 KXX77972.1 - 0.0044 16.9 0.2 0.022 14.7 0.2 2.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL Syntaxin_2 PF14523.1 KXX77972.1 - 0.068 13.2 2.9 2.8 8.0 0.0 3.9 4 1 0 4 4 4 0 Syntaxin-like protein DUF3138 PF11336.3 KXX77972.1 - 0.072 11.2 0.7 0.15 10.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 KXX77972.1 - 0.13 12.1 8.1 0.79 9.5 0.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TraF_2 PF13729.1 KXX77972.1 - 0.24 10.1 3.2 0.89 8.2 0.1 2.5 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein NPV_P10 PF05531.7 KXX77972.1 - 0.7 10.1 7.3 0.49 10.6 0.1 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein COMP PF11598.3 KXX77972.1 - 0.77 9.8 3.1 28 4.8 0.0 3.5 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein LsmAD PF06741.8 KXX77974.1 - 7.2e-22 77.2 2.5 7.2e-22 77.2 1.8 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 KXX77974.1 - 0.00021 21.1 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Chitin_bind_3 PF03067.10 KXX77975.1 - 0.053 13.7 0.1 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 Chitin binding domain Serglycin PF04360.7 KXX77975.1 - 0.24 11.1 0.1 0.24 11.1 0.0 3.7 2 1 0 2 2 2 0 Serglycin HMGL-like PF00682.14 KXX77976.1 - 1.5e-38 132.8 0.0 6.6e-28 97.9 0.0 2.0 2 0 0 2 2 2 2 HMGL-like DS PF01916.12 KXX77977.1 - 1.6e-144 480.5 0.0 1.8e-144 480.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KXX77977.1 - 0.041 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 KXX77978.1 - 1.4e-08 34.6 1.1 0.00022 21.2 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Methyltransf_23 PF13489.1 KXX77979.1 - 6e-07 29.3 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SRP54_N PF02881.14 KXX77979.1 - 0.039 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Methyltransf_31 PF13847.1 KXX77979.1 - 0.096 12.2 0.0 0.74 9.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KXX77980.1 - 9.8e-36 123.1 0.0 1.3e-34 119.4 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 KXX77980.1 - 0.029 14.1 0.1 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_18 PF12847.2 KXX77980.1 - 0.066 13.7 0.0 0.27 11.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain AAA_33 PF13671.1 KXX77980.1 - 0.15 11.9 1.3 0.26 11.1 0.3 1.8 2 0 0 2 2 2 0 AAA domain p450 PF00067.17 KXX77981.1 - 3.4e-42 144.5 0.0 3.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX77982.1 - 3e-23 82.0 0.0 5e-23 81.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KXX77982.1 - 0.0084 14.6 0.1 0.012 14.2 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease MBOAT_2 PF13813.1 KXX77983.1 - 1.2e-19 70.1 4.7 3e-19 68.8 3.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 KXX77984.1 - 1.3e-64 218.4 0.0 1.5e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2762 PF10960.3 KXX77984.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF92 PF01940.11 KXX77984.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 Methyltransf_23 PF13489.1 KXX77985.1 - 4.7e-14 52.4 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77985.1 - 1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77985.1 - 1.3e-10 41.6 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77985.1 - 2.9e-09 37.2 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77985.1 - 3.2e-09 36.5 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77985.1 - 6.1e-09 35.3 0.0 5.4e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KXX77985.1 - 8e-08 32.8 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX77985.1 - 4.9e-06 26.5 0.5 1.2e-05 25.3 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX77985.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX77985.1 - 0.00047 20.1 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PepSY_2 PF13670.1 KXX77985.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.4 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain MTS PF05175.9 KXX77985.1 - 0.0072 15.7 0.1 1.2 8.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase small domain PCMT PF01135.14 KXX77985.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GST_N_2 PF13409.1 KXX77986.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX77986.1 - 0.00036 20.6 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KXX77986.1 - 0.005 16.9 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Virul_fac_BrkB PF03631.10 KXX77987.1 - 0.0048 16.3 3.8 0.0048 16.3 2.6 1.7 1 1 1 2 2 2 1 Virulence factor BrkB NmrA PF05368.8 KXX77988.1 - 3.1e-24 85.5 0.7 3.9e-24 85.1 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX77988.1 - 3.2e-14 53.3 0.4 6.8e-14 52.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX77988.1 - 0.0017 17.4 0.2 0.014 14.3 0.0 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KXX77988.1 - 0.0034 16.8 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family LuxQ-periplasm PF09308.5 KXX77988.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic Methyltransf_11 PF08241.7 KXX77989.1 - 5.1e-10 39.7 0.0 9.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77989.1 - 3.2e-06 27.4 0.0 5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX77989.1 - 0.00096 19.1 0.1 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77989.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX77989.1 - 0.0024 17.6 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77989.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KXX77989.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KXX77990.1 - 1.1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX77990.1 - 9.4e-07 29.2 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX77990.1 - 4.4e-06 27.2 0.0 1.6e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX77990.1 - 1.1e-05 25.1 0.0 0.00015 21.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX77990.1 - 0.0003 21.2 0.0 0.00072 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX77990.1 - 0.00062 20.0 0.0 0.013 15.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX77990.1 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KXX77990.1 - 0.02 14.8 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase AMP-binding PF00501.23 KXX77992.1 - 3.2e-73 246.5 0.1 4.5e-73 246.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KXX77992.1 - 2.8e-48 164.3 0.0 6.5e-23 81.0 0.0 3.4 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KXX77992.1 - 1.5e-16 60.4 0.0 1.9e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX77992.1 - 0.15 13.0 1.4 0.32 11.9 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KXX77993.1 - 7.8e-07 28.8 7.6 2.4e-06 27.3 5.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.2 KXX77993.1 - 0.057 13.7 0.3 2.5 8.4 0.2 3.0 1 1 0 1 1 1 0 DinB superfamily Fungal_trans_2 PF11951.3 KXX77993.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pyr_redox_2 PF07992.9 KXX77994.1 - 2.9e-20 73.0 0.0 6.2e-20 71.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX77994.1 - 6.7e-09 35.0 0.0 2.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX77994.1 - 4.1e-05 22.6 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KXX77994.1 - 0.00011 21.2 0.0 0.00026 19.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KXX77994.1 - 0.00025 20.1 0.1 0.00048 19.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KXX77994.1 - 0.00065 19.8 0.0 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX77994.1 - 0.0016 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX77994.1 - 0.0021 18.0 0.1 0.0054 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX77994.1 - 0.0023 16.4 0.0 0.0042 15.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KXX77994.1 - 0.019 14.0 0.2 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX77994.1 - 0.045 14.0 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX77994.1 - 0.045 12.6 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KXX77994.1 - 0.14 10.9 0.0 4.6 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AIG2_2 PF13772.1 KXX77995.1 - 2.4e-06 27.5 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Abhydrolase_5 PF12695.2 KXX77995.1 - 0.0074 16.0 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 KXX77996.1 - 5.4e-38 130.8 0.0 6.9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KXX77996.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_S10 PF00450.17 KXX77997.1 - 3.2e-63 214.3 0.0 3.8e-58 197.6 0.0 2.3 1 1 1 2 2 2 2 Serine carboxypeptidase TFIIA PF03153.8 KXX77999.1 - 0.0097 15.8 2.9 0.012 15.4 2.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.4 KXX77999.1 - 1.7 8.6 10.7 2.4 8.1 7.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CobT PF06213.7 KXX77999.1 - 1.9 7.5 10.6 2.5 7.1 7.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 KXX77999.1 - 3.9 5.8 8.5 4.3 5.7 5.5 1.3 1 1 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KXX77999.1 - 6.5 5.3 11.6 7.8 5.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_1 PF00583.19 KXX78000.1 - 8.2e-06 25.7 0.1 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX78000.1 - 0.0003 20.8 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX78000.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 KXX78000.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 KXX78001.1 - 1.2e-15 57.1 1.2 2.6e-15 56.0 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX78001.1 - 1e-10 41.3 0.2 2.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like F-box PF00646.28 KXX78002.1 - 1.6e-05 24.4 0.6 4e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX78002.1 - 4.6e-05 23.0 0.8 0.00014 21.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like Peptidase_C53 PF05550.6 KXX78002.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 IQ PF00612.22 KXX78002.1 - 0.21 11.3 0.8 0.44 10.3 0.6 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pyr_redox_2 PF07992.9 KXX78003.1 - 4.8e-19 69.0 0.4 7e-19 68.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX78003.1 - 2.1e-07 30.1 0.0 5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX78003.1 - 4.3e-06 25.8 6.6 1e-05 24.6 0.4 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX78003.1 - 4.5e-06 25.3 0.0 7.4e-05 21.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KXX78003.1 - 7.5e-06 25.0 0.5 0.001 18.0 0.4 2.2 1 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KXX78003.1 - 8.7e-06 25.5 0.7 0.12 12.1 0.0 2.4 1 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX78003.1 - 1.1e-05 25.6 0.1 0.019 14.9 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX78003.1 - 3.3e-05 23.1 0.2 6e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX78003.1 - 6.1e-05 22.9 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX78003.1 - 0.00035 19.7 0.1 0.00095 18.3 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KXX78003.1 - 0.00084 18.5 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX78003.1 - 0.0015 18.7 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX78003.1 - 0.0042 16.0 0.2 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KXX78003.1 - 0.019 13.6 0.1 0.029 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KXX78003.1 - 0.041 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TauD PF02668.11 KXX78006.1 - 1.3e-30 106.9 0.0 1.6e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX78006.1 - 0.0013 17.7 0.1 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 CsiD Ecl1 PF12855.2 KXX78007.1 - 1.3e-12 46.8 2.4 2e-12 46.1 1.7 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KXX78007.1 - 0.0015 17.7 1.5 0.0026 16.9 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF581) C1_1 PF00130.17 KXX78007.1 - 0.16 11.6 3.2 0.24 11.1 2.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF329 PF03884.9 KXX78007.1 - 2.1 7.9 6.4 0.27 10.8 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF329) XhlA PF10779.4 KXX78008.1 - 0.00069 19.4 1.5 0.01 15.7 1.0 2.2 1 1 0 1 1 1 1 Haemolysin XhlA HSBP1 PF06825.7 KXX78008.1 - 0.00093 18.7 1.9 0.0099 15.4 1.3 2.5 1 1 0 1 1 1 1 Heat shock factor binding protein 1 UPF0184 PF03670.8 KXX78008.1 - 0.0013 18.8 0.4 0.013 15.6 0.3 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.7 KXX78008.1 - 0.002 16.4 0.1 0.0026 16.0 0.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Vac_Fusion PF02346.11 KXX78008.1 - 0.0026 17.1 2.4 0.042 13.2 1.9 2.6 2 1 0 2 2 2 1 Chordopoxvirus fusion protein NPV_P10 PF05531.7 KXX78008.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.1 KXX78008.1 - 0.0072 16.4 1.0 3.2 7.9 0.2 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) Tropomyosin PF00261.15 KXX78008.1 - 0.011 14.8 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin Hpt PF01627.18 KXX78008.1 - 0.014 15.3 0.4 0.51 10.3 0.1 2.2 1 1 1 2 2 2 0 Hpt domain Nsp1_C PF05064.8 KXX78008.1 - 0.017 14.7 0.1 0.043 13.4 0.0 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 KXX78008.1 - 0.018 14.9 0.1 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 KXX78008.1 - 0.018 14.7 0.1 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KXX78008.1 - 0.019 14.7 0.1 0.041 13.7 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KXX78008.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein MtrG PF04210.8 KXX78008.1 - 0.025 14.2 0.6 2.1 8.0 0.1 2.4 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ADIP PF11559.3 KXX78008.1 - 0.027 14.3 0.3 0.11 12.3 0.2 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YvrJ PF12841.2 KXX78008.1 - 0.029 13.6 2.2 5.5 6.3 0.0 3.1 3 1 0 3 3 3 0 YvrJ protein family COG5 PF10392.4 KXX78008.1 - 0.034 14.1 0.1 9 6.2 0.0 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 KXX78008.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) RmuC PF02646.11 KXX78008.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 RmuC family Allexi_40kDa PF05549.6 KXX78008.1 - 0.038 13.2 0.2 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1978 PF09321.5 KXX78008.1 - 0.051 13.0 0.2 0.072 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Snapin_Pallidin PF14712.1 KXX78008.1 - 0.061 13.6 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.7 KXX78008.1 - 0.065 12.9 0.1 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Laminin Domain II Osmo_CC PF08946.5 KXX78008.1 - 0.069 13.1 0.2 0.069 13.1 0.1 2.7 3 1 0 3 3 1 0 Osmosensory transporter coiled coil PilJ PF13675.1 KXX78008.1 - 0.083 13.2 0.3 1.3 9.4 0.1 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Occludin_ELL PF07303.8 KXX78008.1 - 0.088 13.5 0.3 0.35 11.6 0.1 2.1 2 1 0 2 2 1 0 Occludin homology domain MscS_porin PF12795.2 KXX78008.1 - 0.088 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain vATP-synt_E PF01991.13 KXX78008.1 - 0.09 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit FH2 PF02181.18 KXX78008.1 - 0.095 11.5 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain BLOC1_2 PF10046.4 KXX78008.1 - 0.1 12.7 0.1 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynactin_p22 PF07426.6 KXX78008.1 - 0.11 11.8 0.0 6.1 6.0 0.0 2.2 1 1 1 2 2 2 0 Dynactin subunit p22 Viral_P18 PF04521.8 KXX78008.1 - 0.13 11.7 0.4 11 5.4 0.0 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2730 PF10805.3 KXX78008.1 - 0.15 11.8 0.5 1.3 8.8 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2428 PF10350.4 KXX78010.1 - 8.8e-68 228.0 0.1 2.3e-67 226.7 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KXX78010.1 - 2.4e-05 24.0 15.4 3 8.1 0.1 7.7 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KXX78010.1 - 0.00018 21.7 1.8 0.28 11.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 KXX78010.1 - 0.48 10.9 5.8 20 5.8 0.1 5.3 5 0 0 5 5 5 0 HEAT-like repeat CoaE PF01121.15 KXX78011.1 - 2.4e-43 147.6 0.0 1e-42 145.5 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KXX78011.1 - 0.0011 19.7 1.0 0.0033 18.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX78011.1 - 0.0093 15.8 0.0 0.071 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain CcmH PF03918.9 KXX78011.1 - 0.012 14.6 1.2 0.02 13.8 0.8 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein AAA_18 PF13238.1 KXX78011.1 - 0.028 14.7 0.4 0.26 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain FixP_N PF14715.1 KXX78011.1 - 0.43 9.9 4.8 0.8 9.1 3.4 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Lectin_leg-like PF03388.8 KXX78012.1 - 7.8e-26 90.6 0.0 1.4e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.7 KXX78012.1 - 0.00031 20.5 0.3 0.011 15.5 0.0 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4602 PF15375.1 KXX78012.1 - 0.0014 18.6 1.4 0.0028 17.7 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) DUF3708 PF12501.3 KXX78012.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter SpoIIIAH PF12685.2 KXX78012.1 - 0.14 11.6 6.8 0.23 10.9 4.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein MtrG PF04210.8 KXX78012.1 - 0.2 11.3 0.6 7.4 6.3 0.0 2.7 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4175 PF13779.1 KXX78012.1 - 0.29 8.7 17.2 0.38 8.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 KXX78012.1 - 2.3 6.9 14.5 3 6.5 10.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ARGLU PF15346.1 KXX78012.1 - 5.7 6.6 13.4 0.11 12.2 4.0 1.8 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Peptidase_M24 PF00557.19 KXX78013.1 - 1.9e-59 200.7 0.0 3.9e-59 199.7 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KXX78013.1 - 2.4e-21 75.5 0.0 5.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WAC_Acf1_DNA_bd PF10537.4 KXX78014.1 - 2.5e-39 133.5 0.0 1.5e-38 131.0 0.0 2.4 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KXX78014.1 - 3.6e-17 61.8 0.2 6e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KXX78014.1 - 3.4e-14 52.0 0.5 7.5e-14 51.0 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KXX78014.1 - 0.00091 19.0 0.4 0.003 17.4 0.0 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KXX78014.1 - 0.0038 16.9 0.2 0.011 15.4 0.2 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF87 PF01935.12 KXX78014.1 - 0.051 13.3 1.6 0.15 11.8 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 Fijivirus_P9-2 PF06837.6 KXX78014.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein Alg6_Alg8 PF03155.10 KXX78015.1 - 3.9e-145 484.2 30.7 5.1e-145 483.9 21.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Fungal_trans_2 PF11951.3 KXX78016.1 - 0.01 14.4 0.4 0.014 13.9 0.3 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78016.1 - 0.08 12.8 8.2 0.18 11.7 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_transf_N PF04413.11 KXX78016.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Thioredoxin_6 PF13848.1 KXX78017.1 - 4.2e-20 72.3 0.0 6.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Kelch_5 PF13854.1 KXX78018.1 - 4.3e-13 48.9 15.7 1.9e-12 46.8 0.2 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 KXX78018.1 - 2.3e-05 24.0 14.6 1.9 8.2 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KXX78018.1 - 0.003 17.6 15.4 2.3 8.5 0.1 5.9 6 1 1 7 7 7 3 Kelch motif Herpes_gE PF02480.11 KXX78018.1 - 0.023 12.9 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_2 PF07646.10 KXX78018.1 - 1.9 8.3 9.4 30 4.6 0.0 5.0 6 0 0 6 6 6 0 Kelch motif MFS_1 PF07690.11 KXX78019.1 - 4.6e-35 120.9 51.1 1.6e-34 119.2 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN7 PF10602.4 KXX78020.1 - 9.3e-48 161.9 0.0 1.5e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KXX78020.1 - 2.3e-13 50.3 0.1 8.2e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain Fungal_trans PF04082.13 KXX78021.1 - 1.3e-31 109.4 0.0 1.8e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78021.1 - 1.5e-10 40.8 14.6 2.7e-10 39.9 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 KXX78022.1 - 0.00064 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KXX78022.1 - 0.0054 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX78022.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NDUF_B4 PF07225.7 KXX78023.1 - 0.0025 17.5 0.1 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Tim17 PF02466.14 KXX78024.1 - 4.8e-29 101.0 2.4 6e-29 100.6 1.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABC2_membrane_4 PF12730.2 KXX78025.1 - 1.4 8.0 7.1 9.8 5.2 4.9 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein Abhydrolase_6 PF12697.2 KXX78026.1 - 6.9e-06 26.1 3.2 1.1e-05 25.4 0.1 2.7 2 2 1 3 3 3 1 Alpha/beta hydrolase family LCAT PF02450.10 KXX78026.1 - 0.0044 16.0 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KXX78026.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Gtr1_RagA PF04670.7 KXX78027.1 - 5.7e-71 238.3 0.1 7.2e-71 237.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KXX78027.1 - 0.00094 19.6 0.0 0.0076 16.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX78027.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MIF PF01187.13 KXX78028.1 - 1.7e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) mono-CXXC PF15626.1 KXX78028.1 - 0.087 12.7 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 single CXXC unit SAP18 PF06487.7 KXX78029.1 - 8.2e-33 112.7 0.0 9.9e-33 112.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Dscam_C PF12355.3 KXX78029.1 - 0.087 13.0 4.1 0.2 11.9 2.9 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Prp18 PF02840.10 KXX78030.1 - 3.7e-51 172.7 1.4 4.3e-51 172.5 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KXX78030.1 - 7.9e-11 41.0 0.4 7.9e-11 41.0 0.3 3.5 3 1 1 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Ycf1 PF05758.7 KXX78030.1 - 0.39 8.3 4.7 0.41 8.3 3.2 1.1 1 0 0 1 1 1 0 Ycf1 E1-E2_ATPase PF00122.15 KXX78031.1 - 1.4e-57 194.3 2.8 1.4e-57 194.3 2.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX78031.1 - 1e-42 145.7 5.4 1e-42 145.7 3.7 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX78031.1 - 2.9e-30 106.2 0.0 1.9e-29 103.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX78031.1 - 8.2e-20 70.5 0.0 1.6e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX78031.1 - 4.3e-17 62.9 0.0 8.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX78031.1 - 8.4e-07 28.3 0.3 1.5e-05 24.3 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KXX78031.1 - 2.8e-06 27.0 0.6 5.7e-06 26.1 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 KXX78031.1 - 0.0093 14.7 3.7 0.023 13.4 2.6 1.6 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family DUF2976 PF11190.3 KXX78031.1 - 0.055 13.0 9.0 0.095 12.2 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Pkinase PF00069.20 KXX78032.1 - 4.4e-17 62.0 0.0 8.6e-17 61.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78032.1 - 6.7e-08 31.9 0.0 1.8e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF533 PF04391.7 KXX78032.1 - 4.8 6.4 13.2 11 5.3 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SIR2 PF02146.12 KXX78033.1 - 7.4e-60 201.7 0.0 1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KXX78033.1 - 0.0029 17.1 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KXX78033.1 - 0.096 12.4 0.1 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ESSS PF10183.4 KXX78034.1 - 5.3e-27 94.2 2.3 8e-27 93.6 1.6 1.4 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Piwi PF02171.12 KXX78035.1 - 1.5e-73 247.4 0.0 2.1e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KXX78035.1 - 4.2e-09 35.6 0.0 8.1e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Glucosamine_iso PF01182.15 KXX78036.1 - 3.2e-27 95.5 0.0 5.4e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aminotran_4 PF01063.14 KXX78038.1 - 6.5e-32 110.8 0.0 1.8e-31 109.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class IV RAP1 PF07218.6 KXX78039.1 - 1.9 6.5 3.6 2.2 6.2 2.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PEMT PF04191.8 KXX78040.1 - 3.2e-31 107.5 4.7 3.2e-31 107.5 3.2 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NDT80_PhoG PF05224.7 KXX78041.1 - 3e-34 118.6 0.0 6.3e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Dicty_REP PF05086.7 KXX78041.1 - 6.1 4.4 4.1 8.6 3.9 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hexokinase_2 PF03727.11 KXX78042.1 - 1e-33 116.5 0.0 8.6e-31 106.9 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KXX78042.1 - 7.8e-30 103.7 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Noggin PF05806.7 KXX78042.1 - 0.0042 16.4 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Noggin Pyridox_ox_2 PF12900.2 KXX78043.1 - 5.8e-38 129.9 0.0 8.5e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spermine_synth PF01564.12 KXX78044.1 - 9.3e-09 34.5 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 KXX78044.1 - 0.00093 18.9 0.0 0.0099 15.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78044.1 - 0.0041 17.6 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Na_H_Exchanger PF00999.16 KXX78046.1 - 7.7e-67 225.4 39.4 1.1e-66 224.9 27.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.9 KXX78047.1 - 4.3e-32 111.6 0.3 8.2e-32 110.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 KXX78047.1 - 1.2e-21 76.6 0.4 4e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.22 KXX78047.1 - 1.1e-18 67.4 1.5 9.3e-17 61.2 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 KXX78047.1 - 7.2e-15 54.7 1.7 2.1e-12 46.9 2.9 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 KXX78047.1 - 2.6e-13 49.6 0.0 1.4e-12 47.2 0.0 2.2 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 KXX78047.1 - 6.9e-11 41.5 0.0 5.2e-10 38.7 0.0 2.5 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KXX78047.1 - 1.2e-08 34.4 0.0 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KXX78047.1 - 6.4e-07 29.6 0.0 0.00027 21.0 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX78047.1 - 4.1e-06 25.9 1.9 0.18 10.6 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX78047.1 - 0.00017 21.3 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX78047.1 - 0.021 13.7 0.0 0.056 12.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KXX78047.1 - 0.042 14.0 0.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KXX78047.1 - 0.11 12.4 0.6 10 6.1 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Glyco_hydro_3 PF00933.16 KXX78049.1 - 3.5e-55 187.0 0.0 5.3e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX78049.1 - 0.0003 20.4 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KXX78049.1 - 0.0015 18.5 0.6 0.0056 16.6 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX78049.1 - 0.0093 16.1 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.12 KXX78049.1 - 0.018 15.0 0.3 5.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Iron hydrogenase small subunit Acetyltransf_10 PF13673.1 KXX78049.1 - 0.046 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 KXX78050.1 - 3.1e-18 66.7 0.1 2.1e-17 64.0 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX78050.1 - 6.4e-07 29.3 0.1 6.3e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KXX78050.1 - 2e-06 27.2 0.0 4.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KXX78050.1 - 4.6e-05 23.1 0.0 0.0002 21.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Pox_A_type_inc PF04508.7 KXX78050.1 - 0.22 11.4 0.3 0.52 10.2 0.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ceramidase_alk PF04734.8 KXX78051.1 - 4.2e-284 943.6 0.0 4.8e-284 943.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Rcd1 PF04078.8 KXX78052.1 - 2.3e-131 436.3 3.1 2.8e-131 436.1 2.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like zf-MYND PF01753.13 KXX78053.1 - 8.5e-12 44.7 13.4 2.1e-11 43.5 9.3 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KXX78053.1 - 0.045 13.6 7.5 0.12 12.2 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KXX78053.1 - 5 6.4 10.9 5.5 6.3 6.1 2.2 2 1 0 2 2 2 0 Life-span regulatory factor F-box-like PF12937.2 KXX78054.1 - 1.9e-08 33.9 0.3 5.5e-08 32.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KXX78054.1 - 0.0003 20.4 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 KXX78054.1 - 0.0063 16.1 0.7 0.0063 16.1 0.5 2.8 3 1 0 3 3 3 1 F-box domain HALZ PF02183.13 KXX78054.1 - 0.052 13.2 0.3 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sugar_tr PF00083.19 KXX78055.1 - 5.2e-107 358.2 20.2 6.2e-107 357.9 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX78055.1 - 1.5e-21 76.4 27.4 1.5e-21 76.4 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 KXX78055.1 - 0.26 10.9 1.5 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel adh_short PF00106.20 KXX78056.1 - 8.1e-24 84.4 1.1 1.5e-23 83.5 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX78056.1 - 2.6e-11 43.7 0.1 3.6e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX78056.1 - 1.4e-07 31.3 5.5 4.2e-06 26.5 3.9 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KXX78056.1 - 0.0015 18.0 0.1 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX78056.1 - 0.011 15.7 0.3 0.029 14.3 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 KXX78056.1 - 0.06 12.4 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HDPD PF02924.9 KXX78056.1 - 0.15 11.8 1.4 0.16 11.7 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Pkinase PF00069.20 KXX78057.1 - 2.4e-10 40.0 0.0 9e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KXX78059.1 - 1.6e-32 110.1 10.5 1.3e-08 34.3 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KXX78059.1 - 3.1e-32 110.4 14.3 5.4e-32 109.6 9.9 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KXX78059.1 - 6.6e-06 25.8 0.3 0.033 13.9 0.0 4.5 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KXX78059.1 - 0.0085 16.3 1.6 5.7 7.3 0.0 4.4 4 1 1 5 5 5 1 PQQ-like domain Cytochrom_D1 PF02239.11 KXX78059.1 - 0.0086 14.4 0.1 0.033 12.5 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain PCI PF01399.22 KXX78060.1 - 2.8e-20 72.5 0.9 9.1e-20 70.9 0.1 2.3 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.1 KXX78060.1 - 8e-07 28.4 2.8 0.22 11.4 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX78060.1 - 2e-06 27.1 3.0 4.4 7.3 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78060.1 - 0.00084 19.9 12.8 1.2 9.9 0.3 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat DDRGK PF09756.4 KXX78060.1 - 0.00094 18.6 0.2 0.00094 18.6 0.1 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_2 PF07719.12 KXX78060.1 - 0.0013 18.5 5.8 7.3 6.7 0.0 5.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX78060.1 - 0.01 15.4 5.9 7.1 6.4 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX78060.1 - 0.033 14.1 18.6 0.06 13.2 0.3 5.3 3 1 2 6 6 6 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KXX78060.1 - 0.036 13.8 0.3 0.077 12.7 0.2 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 KXX78060.1 - 0.1 13.2 12.1 17 6.3 0.1 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF87 PF01935.12 KXX78060.1 - 0.21 11.3 2.0 0.68 9.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 TPR_10 PF13374.1 KXX78060.1 - 0.41 10.6 4.3 9 6.3 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX78060.1 - 0.51 10.9 0.1 0.51 10.9 0.1 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat AT_hook PF02178.14 KXX78061.1 - 0.0093 15.5 18.9 0.55 10.0 3.1 3.5 2 0 0 2 2 2 2 AT hook motif Kdo_hydroxy PF11004.3 KXX78062.1 - 0.13 11.2 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase WD40 PF00400.27 KXX78063.1 - 3.8e-19 67.7 3.0 2e-06 27.4 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KXX78063.1 - 1.6e-06 27.4 0.2 0.00032 20.1 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 KXX78063.1 - 0.023 14.4 0.0 0.79 9.3 0.0 2.9 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.11 KXX78064.1 - 9.1e-36 123.2 49.5 9.1e-36 123.2 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX78064.1 - 1.6e-11 43.4 15.7 1.6e-11 43.4 10.9 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 KXX78064.1 - 0.13 11.9 0.3 0.43 10.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Mob1_phocein PF03637.12 KXX78065.1 - 6.2e-70 234.4 0.0 7.9e-70 234.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.11 KXX78066.1 - 1.5e-08 33.0 2.2 1.2e-05 23.4 0.0 3.2 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase CEP44 PF15007.1 KXX78066.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 OSCP PF00213.13 KXX78067.1 - 4.3e-45 153.6 0.5 5e-45 153.4 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Conotoxin PF02950.12 KXX78068.1 - 0.0012 19.5 0.8 0.0014 19.4 0.5 1.3 1 0 0 1 1 1 1 Conotoxin Agouti PF05039.7 KXX78068.1 - 0.031 14.5 1.9 0.034 14.4 1.3 1.1 1 0 0 1 1 1 0 Agouti protein Omega-toxin PF06357.6 KXX78068.1 - 0.04 13.4 5.2 0.057 13.0 3.6 1.3 1 0 0 1 1 1 0 Omega-atracotoxin UPF0506 PF11703.3 KXX78068.1 - 0.059 13.3 5.1 0.083 12.8 3.5 1.3 1 0 0 1 1 1 0 UPF0506 PP2C PF00481.16 KXX78069.1 - 1.2e-42 146.1 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KXX78069.1 - 0.0018 17.7 0.3 0.0058 16.0 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KXX78069.1 - 0.0048 16.6 0.1 0.6 9.7 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.11 KXX78070.1 - 2.5e-16 59.3 20.7 1.5e-15 56.7 11.2 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Flexi_CP_N PF08358.5 KXX78071.1 - 0.019 14.7 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Carlavirus coat LSM PF01423.17 KXX78072.1 - 1.1e-13 50.4 0.1 2.5e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 LSM domain Sds3 PF08598.6 KXX78073.1 - 1.4e-49 168.4 5.9 1.4e-49 168.4 4.1 1.7 1 1 1 2 2 2 1 Sds3-like AntA PF08346.7 KXX78073.1 - 0.044 13.9 0.7 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 AntA/AntB antirepressor DUF1751 PF08551.5 KXX78074.1 - 3.4e-28 97.8 4.0 3.7e-28 97.7 1.8 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KXX78074.1 - 0.033 14.1 10.7 0.077 13.0 7.4 1.6 1 0 0 1 1 1 0 Rhomboid family WW PF00397.21 KXX78075.1 - 2.8e-09 36.6 0.1 2.8e-09 36.6 0.1 2.5 3 0 0 3 3 3 1 WW domain p450 PF00067.17 KXX78075.1 - 0.0014 17.2 0.3 0.0021 16.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1754 PF08555.5 KXX78076.1 - 6.4e-15 55.5 14.0 1.3e-14 54.5 9.7 1.5 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DDHD PF02862.12 KXX78076.1 - 0.058 13.1 5.1 0.071 12.8 3.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF1978 PF09321.5 KXX78076.1 - 0.1 12.0 5.8 0.18 11.2 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Pox_A_type_inc PF04508.7 KXX78076.1 - 0.13 12.1 2.9 5.9 6.9 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Red1 PF07964.6 KXX78076.1 - 0.24 9.5 5.9 0.27 9.3 4.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 IncA PF04156.9 KXX78076.1 - 0.33 10.5 6.4 0.45 10.0 4.4 1.2 1 0 0 1 1 1 0 IncA protein SpoIIIAH PF12685.2 KXX78076.1 - 0.58 9.6 4.3 0.7 9.3 3.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Leu_zip PF15294.1 KXX78076.1 - 0.64 9.0 8.6 0.9 8.5 3.9 1.9 2 0 0 2 2 2 0 Leucine zipper Host_attach PF10116.4 KXX78076.1 - 0.83 9.8 5.8 1.7 8.8 4.0 1.7 1 1 0 1 1 1 0 Protein required for attachment to host cells PRKCSH-like PF12999.2 KXX78076.1 - 1.4 8.4 4.0 0.57 9.7 1.1 1.5 2 0 0 2 2 2 0 Glucosidase II beta subunit-like RR_TM4-6 PF06459.7 KXX78076.1 - 2.6 7.8 8.8 3.3 7.5 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 cobW PF02492.14 KXX78078.1 - 5.2e-36 123.7 0.0 7.9e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KXX78078.1 - 0.0041 16.8 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KXX78078.1 - 0.0092 15.7 0.1 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KXX78078.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KXX78078.1 - 0.13 11.8 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KXX78078.1 - 0.13 11.7 0.0 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AA_permease PF00324.16 KXX78079.1 - 1.6e-59 201.5 29.7 2.1e-59 201.1 20.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX78079.1 - 5.4e-15 54.8 36.5 7.7e-15 54.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease PALP PF00291.20 KXX78080.1 - 4.8e-62 209.9 0.2 6.1e-62 209.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_pol_E_B PF04042.11 KXX78081.1 - 1.5e-52 177.9 0.0 1.9e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA-synt_1g PF09334.6 KXX78082.1 - 6.7e-115 383.8 0.2 1.2e-114 382.9 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KXX78082.1 - 1.4e-23 82.8 5.8 1.3e-09 36.6 0.0 4.0 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KXX78082.1 - 3.6e-09 36.1 0.0 0.00054 19.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KXX78082.1 - 0.0073 16.0 0.0 0.063 13.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Acetyltransf_3 PF13302.1 KXX78083.1 - 2.4e-21 76.3 0.0 3.3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX78083.1 - 4.2e-08 33.1 0.4 0.00041 20.2 0.4 2.8 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX78083.1 - 2e-06 27.4 0.2 0.0039 16.8 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KXX78083.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KXX78083.1 - 0.001 19.0 0.1 0.0097 15.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Dak1 PF02733.12 KXX78084.1 - 1.3e-110 368.9 7.8 1.8e-110 368.5 5.4 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KXX78084.1 - 7.1e-45 152.8 0.8 1.5e-44 151.7 0.5 1.6 1 0 0 1 1 1 1 DAK2 domain Asparaginase PF00710.15 KXX78085.1 - 4e-90 301.8 0.0 4.5e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Asparaginase NPV_P10 PF05531.7 KXX78086.1 - 0.1 12.8 1.1 5.5 7.3 0.7 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IF4E PF01652.13 KXX78087.1 - 4.7e-39 133.5 0.4 6e-39 133.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mitofilin PF09731.4 KXX78088.1 - 0.21 10.2 2.0 0.24 10.0 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CTP_transf_1 PF01148.15 KXX78089.1 - 9.5e-05 22.1 17.9 0.00019 21.1 7.3 3.0 3 1 0 3 3 3 1 Cytidylyltransferase family Lactamase_B PF00753.22 KXX78090.1 - 5.6e-30 104.4 2.0 7.2e-30 104.0 1.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KXX78090.1 - 1.2e-06 28.2 0.3 1.8e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1236 PF06823.7 KXX78090.1 - 0.009 15.7 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1236) Lactamase_B_3 PF13483.1 KXX78090.1 - 0.011 15.4 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Las1 PF04031.8 KXX78091.1 - 9e-62 207.2 0.0 1.2e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Las1-like Enolase_C PF00113.17 KXX78092.1 - 6.6e-153 507.8 0.1 8.4e-153 507.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KXX78092.1 - 3.6e-58 195.1 0.3 7.1e-58 194.2 0.1 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 KXX78092.1 - 0.016 14.1 0.1 0.51 9.2 0.1 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KXX78092.1 - 0.034 14.6 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_M1 PF01433.15 KXX78093.1 - 1.7e-141 471.8 0.1 2.3e-141 471.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KXX78093.1 - 2.7e-91 306.2 0.0 5.2e-91 305.2 0.0 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KXX78093.1 - 2.6e-20 72.7 0.2 5.2e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Kelch_3 PF13415.1 KXX78094.1 - 7e-29 99.3 15.2 3.8e-09 36.4 0.0 7.4 9 0 0 9 9 9 4 Galactose oxidase, central domain DUF4110 PF13422.1 KXX78094.1 - 7.8e-29 99.3 0.0 7.8e-29 99.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 KXX78094.1 - 9.6e-25 86.1 12.5 8.6e-06 25.4 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX78094.1 - 3.4e-24 84.3 0.5 1.7e-08 34.1 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KXX78094.1 - 4.9e-18 64.4 1.7 0.00018 21.5 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KXX78094.1 - 9.3e-16 57.1 1.6 1.9e-06 27.3 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KXX78094.1 - 3.7e-15 55.0 2.2 0.00092 18.8 0.0 6.1 6 1 0 6 6 6 3 Kelch motif DUF3534 PF12053.3 KXX78094.1 - 0.028 14.3 0.1 0.028 14.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3534) DUF3597 PF12200.3 KXX78094.1 - 6.3 7.1 9.6 1.1 9.6 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) WLM PF08325.5 KXX78095.1 - 3.3e-51 173.8 0.3 7.2e-51 172.7 0.0 1.6 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KXX78095.1 - 3e-08 33.7 1.5 7.1e-08 32.4 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 CHGN PF05679.11 KXX78095.1 - 0.055 12.1 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase zf-RanBP PF00641.13 KXX78095.1 - 6.2 6.0 10.0 0.48 9.5 3.3 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Saccharop_dh PF03435.13 KXX78096.1 - 1.1e-126 422.9 0.0 1.3e-126 422.6 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KXX78096.1 - 6.3e-05 23.0 0.2 0.00013 22.0 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KXX78096.1 - 0.00011 22.2 0.3 0.0002 21.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 KXX78096.1 - 0.015 14.6 0.3 0.21 10.9 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KXX78096.1 - 0.078 12.9 1.0 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain AP_endonuc_2 PF01261.19 KXX78098.1 - 2.9e-30 105.1 0.1 4.3e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 KXX78099.1 - 4.4e-44 149.2 0.4 1.5e-43 147.5 0.3 1.8 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KXX78099.1 - 7.4e-12 44.9 0.0 2.1e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78099.1 - 0.005 15.9 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Aa_trans PF01490.13 KXX78101.1 - 2.5e-83 279.8 32.7 3e-83 279.5 22.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 KXX78102.1 - 1.1e-20 72.8 0.0 1.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KXX78102.1 - 7.4e-08 31.4 0.0 1.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.17 KXX78103.1 - 8e-21 73.3 0.1 9e-21 73.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 KXX78104.1 - 1.5e-13 50.6 0.0 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 KXX78105.1 - 4.7e-32 108.7 12.4 9.9e-09 34.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 KXX78105.1 - 7.2e-19 67.5 0.1 1.2e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KXX78105.1 - 0.00021 19.5 1.8 0.086 10.9 0.2 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 ECH_C PF13766.1 KXX78106.1 - 4.9e-35 120.2 0.1 1.3e-34 118.9 0.1 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KXX78106.1 - 6.5e-26 90.9 0.0 5.1e-25 88.0 0.0 2.2 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family A_thal_3526 PF09713.5 KXX78106.1 - 0.081 13.0 0.2 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Glyco_hydro_76 PF03663.9 KXX78107.1 - 3.3e-132 441.3 6.0 3.9e-132 441.1 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NAP PF00956.13 KXX78108.1 - 2.3e-51 174.2 7.1 2.3e-51 174.2 4.9 1.7 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) RNase_H PF00075.19 KXX78110.1 - 2e-10 41.1 0.0 3.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KXX78110.1 - 0.00053 19.7 0.0 0.87 9.4 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like FAD_binding_4 PF01565.18 KXX78112.1 - 2.8e-19 68.9 0.4 5.7e-19 67.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX78112.1 - 9.4e-10 38.2 0.2 2.2e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like TPP_enzyme_N PF02776.13 KXX78114.1 - 1.9e-36 125.1 0.1 8.1e-36 123.0 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KXX78114.1 - 1.5e-25 89.6 0.6 1.5e-24 86.2 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KXX78114.1 - 5.8e-22 77.9 0.0 1.3e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2CSK_N PF08521.5 KXX78115.1 - 0.04 13.4 0.1 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 Two-component sensor kinase N-terminal Val_tRNA-synt_C PF10458.4 KXX78116.1 - 0.12 12.4 0.8 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm TPR_6 PF13174.1 KXX78116.1 - 0.14 12.6 0.1 1.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1996 PF09362.5 KXX78117.1 - 8.9e-54 182.6 0.1 1.1e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) peroxidase PF00141.18 KXX78118.1 - 4.2e-23 82.0 0.0 5.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase HET PF06985.6 KXX78121.1 - 2.6e-31 108.6 0.7 2.6e-31 108.6 0.5 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HATPase_c_3 PF13589.1 KXX78121.1 - 4e-05 23.2 0.3 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KXX78121.1 - 0.041 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3611 PF12263.3 KXX78122.1 - 0.00044 19.6 1.3 0.28 10.5 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3611) DDDD PF10161.4 KXX78122.1 - 1.6 8.3 3.3 12 5.6 0.1 3.4 4 0 0 4 4 4 0 Putative mitochondrial precursor protein Abhydrolase_3 PF07859.8 KXX78125.1 - 6.5e-40 136.9 0.0 8.2e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX78125.1 - 2.1e-06 26.7 0.0 3.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KXX78125.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KXX78125.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.15 KXX78126.1 - 6.4e-76 255.2 0.0 1e-75 254.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KXX78126.1 - 5.3e-24 84.5 0.0 7.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KXX78126.1 - 1.8e-07 30.8 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KXX78126.1 - 0.0047 16.1 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CorA PF01544.13 KXX78128.1 - 3.1e-06 26.4 6.8 3.1e-06 26.4 4.7 2.6 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Zot PF05707.7 KXX78128.1 - 0.066 12.6 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TGT_C1 PF14809.1 KXX78128.1 - 0.2 11.5 1.0 0.89 9.4 0.2 2.3 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation Inositol_P PF00459.20 KXX78129.1 - 4.1e-25 88.5 0.4 9.1e-25 87.4 0.3 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Cellulase PF00150.13 KXX78131.1 - 1.5e-17 63.6 5.1 2.2e-17 63.2 2.0 1.8 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KXX78131.1 - 4.1e-07 29.2 0.0 3.8e-06 26.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KXX78131.1 - 7.4e-07 29.5 0.0 3.7e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Sugar-binding cellulase-like DUF4434 PF14488.1 KXX78131.1 - 0.00043 20.0 0.2 0.0095 15.6 0.0 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4434) Glyco_hydro_42 PF02449.10 KXX78131.1 - 0.00052 19.2 0.2 0.0025 16.9 0.0 2.0 2 1 0 3 3 3 1 Beta-galactosidase FAD_binding_3 PF01494.14 KXX78132.1 - 9.4e-17 61.0 2.7 5.3e-10 38.8 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX78132.1 - 2.1e-09 36.7 0.2 4.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX78132.1 - 1e-08 34.5 0.1 1.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX78132.1 - 2.8e-07 30.6 0.1 2e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX78132.1 - 3.8e-07 28.9 0.3 0.0001 20.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KXX78132.1 - 7.3e-07 29.1 0.1 2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KXX78132.1 - 2.8e-05 23.3 0.3 0.00013 21.1 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KXX78132.1 - 3.4e-05 22.8 0.1 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KXX78132.1 - 0.00064 18.7 0.1 0.054 12.4 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KXX78132.1 - 0.0007 19.7 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KXX78132.1 - 0.00096 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KXX78132.1 - 0.0014 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KXX78132.1 - 0.0088 16.4 0.1 0.12 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KXX78132.1 - 0.013 14.6 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KXX78132.1 - 0.079 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KXX78132.1 - 0.099 12.6 0.3 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding Trp_halogenase PF04820.9 KXX78132.1 - 0.11 11.1 0.5 0.72 8.4 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX78132.1 - 0.13 12.0 0.1 16 5.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.17 KXX78133.1 - 6.6e-49 166.6 0.0 1.2e-48 165.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KXX78133.1 - 9.9e-14 51.1 0.0 2.4e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX78133.1 - 1.1e-05 25.5 0.0 3.6e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Rieske PF00355.21 KXX78134.1 - 0.0067 15.9 0.3 0.051 13.1 0.0 2.4 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KXX78134.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-nanos PF05741.8 KXX78135.1 - 0.97 9.4 10.1 1.3 9.0 0.6 4.3 5 1 1 6 6 6 0 Nanos RNA binding domain Bac_rhodopsin PF01036.13 KXX78136.1 - 4.3e-44 150.4 16.3 5.4e-44 150.1 11.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3792 PF12670.2 KXX78136.1 - 0.0035 17.1 13.2 0.056 13.3 3.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3792) DUF202 PF02656.10 KXX78136.1 - 0.029 14.5 4.1 0.029 14.5 2.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) NADH-u_ox-rdase PF10785.4 KXX78136.1 - 0.38 11.0 0.1 0.38 11.0 0.1 3.0 2 2 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DuoxA PF10204.4 KXX78136.1 - 5.6 5.9 13.1 0.15 11.1 3.0 2.4 1 1 2 3 3 3 0 Dual oxidase maturation factor CytochromB561_N PF09786.4 KXX78137.1 - 5.5 5.3 10.4 6.2 5.1 7.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CorA PF01544.13 KXX78138.1 - 4.8e-07 29.0 0.0 7.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PgaD PF13994.1 KXX78138.1 - 0.32 10.4 5.7 0.069 12.6 0.5 2.4 3 0 0 3 3 3 0 PgaD-like protein MAT1 PF06391.8 KXX78139.1 - 3.4e-29 101.8 9.3 4.8e-29 101.3 6.5 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KXX78139.1 - 0.00035 20.1 3.7 0.00073 19.1 2.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX78139.1 - 0.00097 18.7 6.3 0.0014 18.2 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.8 KXX78139.1 - 0.0026 17.0 4.3 0.0033 16.6 3.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_5 PF14634.1 KXX78139.1 - 0.0034 17.0 8.9 0.05 13.3 6.8 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Atg14 PF10186.4 KXX78139.1 - 0.0097 14.8 8.5 0.013 14.4 5.9 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_2 PF13639.1 KXX78139.1 - 0.013 15.2 7.0 0.07 12.9 5.1 1.9 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KXX78139.1 - 0.017 15.1 8.2 0.058 13.4 5.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX78139.1 - 0.077 12.8 6.0 0.52 10.2 4.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KXX78139.1 - 0.42 10.2 9.6 6.1 6.5 7.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain MRP-S26 PF14943.1 KXX78139.1 - 3.3 7.2 20.6 0.35 10.3 11.2 1.6 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Oxidored-like PF09791.4 KXX78139.1 - 4.7 6.7 6.2 4.8 6.7 2.8 2.1 1 1 1 2 2 2 0 Oxidoreductase-like protein, N-terminal Phos_pyr_kin PF08543.7 KXX78140.1 - 2.3e-11 43.3 0.0 4.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KXX78140.1 - 2.5e-08 33.4 0.1 2.2e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PCNA_N PF00705.13 KXX78141.1 - 2.3e-56 188.7 4.6 5.4e-56 187.5 2.6 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KXX78141.1 - 9.8e-52 174.2 0.2 3.1e-51 172.5 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KXX78141.1 - 4.9e-10 38.9 0.1 5.9e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KXX78141.1 - 2.1e-07 29.9 1.3 1.2e-05 24.2 0.9 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 KXX78141.1 - 9.3e-06 24.7 0.2 0.0038 16.2 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein FliW PF02623.10 KXX78141.1 - 0.12 11.9 0.1 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 FliW protein IL12p40_C PF10420.4 KXX78141.1 - 0.13 12.3 0.0 0.61 10.2 0.0 2.1 3 0 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus Vezatin PF12632.2 KXX78142.1 - 4.2e-64 216.0 0.1 1.2e-63 214.5 0.0 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Rab5ip PF07019.7 KXX78143.1 - 2.6e-24 85.1 4.7 3.5e-24 84.7 3.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GTP_EFTU PF00009.22 KXX78144.1 - 5.9e-10 38.8 0.0 3.3e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KXX78144.1 - 0.021 14.3 0.4 0.05 13.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KXX78144.1 - 0.085 12.3 1.1 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SNARE PF05739.14 KXX78145.1 - 0.0005 19.7 4.7 0.0005 19.7 3.3 3.1 3 0 0 3 3 3 2 SNARE domain Metal_resist PF13801.1 KXX78145.1 - 0.015 15.3 0.4 0.015 15.3 0.3 3.3 3 1 0 3 3 3 0 Heavy-metal resistance FHIPEP PF00771.15 KXX78145.1 - 0.19 9.9 2.9 0.28 9.4 2.0 1.2 1 0 0 1 1 1 0 FHIPEP family OEP PF02321.13 KXX78145.1 - 5.8 6.4 16.8 0.2 11.2 5.9 2.5 1 1 1 2 2 2 0 Outer membrane efflux protein HA2 PF04408.18 KXX78146.1 - 7.2e-19 67.7 0.7 1.7e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KXX78146.1 - 2.8e-16 59.3 0.0 9.8e-16 57.6 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KXX78146.1 - 1.2e-13 50.7 0.1 4.3e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX78146.1 - 8.5e-07 28.6 0.0 2.8e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX78146.1 - 1e-06 28.8 0.0 2.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KXX78146.1 - 0.0032 17.7 0.0 0.0086 16.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 KXX78146.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX78146.1 - 0.35 10.8 5.9 0.89 9.5 0.1 3.7 3 1 1 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 KXX78146.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.2 3 1 0 4 4 4 0 AAA domain Complex1_LYR PF05347.10 KXX78147.1 - 2.3e-10 40.0 0.1 4.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX78147.1 - 1.3e-07 31.7 0.3 2e-07 31.0 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KXX78147.1 - 3.7e-06 27.3 0.1 4.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 KXX78147.1 - 0.027 14.0 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Patatin PF01734.17 KXX78148.1 - 3.8e-22 79.2 0.0 1.2e-21 77.5 0.0 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.1 KXX78148.1 - 4e-14 52.3 18.1 5.9e-06 26.1 2.4 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KXX78148.1 - 1.6e-07 30.4 0.0 4.2e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KXX78148.1 - 0.00011 22.2 0.0 0.0031 17.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KXX78148.1 - 0.00041 20.3 0.2 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KXX78148.1 - 0.036 14.2 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX78148.1 - 0.095 13.5 1.4 0.91 10.3 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KXX78148.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain ANTH PF07651.11 KXX78149.1 - 2.1e-72 243.1 0.5 2.8e-72 242.7 0.3 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KXX78149.1 - 3.1e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 KXX78150.1 - 3.9e-53 180.3 0.0 4.7e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2 PF00152.15 KXX78151.1 - 3.6e-39 134.4 0.2 4.9e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KXX78151.1 - 0.04 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Far-17a_AIG1 PF04750.9 KXX78153.1 - 3.8e-06 26.1 11.6 6e-06 25.5 8.0 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein ABC2_membrane_4 PF12730.2 KXX78153.1 - 4.4 6.3 21.0 0.79 8.8 5.6 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein CS PF04969.11 KXX78154.1 - 1.1e-15 57.9 0.0 2.8e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 CS domain Prefoldin_3 PF13758.1 KXX78155.1 - 4.7e-31 106.4 2.8 5.3e-31 106.3 0.6 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 KXX78155.1 - 2.1e-23 83.0 17.1 3.1e-20 72.9 0.0 5.3 5 1 0 5 5 5 2 Domain of unknown function (DUF3835) MIS13 PF08202.6 KXX78155.1 - 0.0018 17.4 1.3 0.0018 17.4 0.9 2.0 2 1 1 3 3 3 1 Mis12-Mtw1 protein family SPX PF03105.14 KXX78155.1 - 0.0055 16.5 0.0 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 SPX domain BTV_NS2 PF04514.7 KXX78155.1 - 0.019 13.8 5.0 0.046 12.6 3.5 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FliJ PF02050.11 KXX78155.1 - 0.69 9.9 7.0 3.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein Uds1 PF15456.1 KXX78155.1 - 1.5 8.8 10.0 1.6 8.7 0.1 3.6 3 1 0 3 3 3 0 Up-regulated During Septation TFIIS_M PF07500.9 KXX78156.1 - 1.3e-22 80.0 1.0 1e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KXX78156.1 - 4.1e-18 64.7 6.0 4.1e-18 64.7 4.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KXX78156.1 - 1.8e-14 52.9 1.5 2.5e-14 52.5 0.3 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ATP-synt_B PF00430.13 KXX78156.1 - 9.1 6.0 10.3 0.28 10.9 1.6 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) TRI12 PF06609.8 KXX78157.1 - 0.022 12.9 0.3 0.025 12.7 0.2 1.0 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) SpoIIE PF07228.7 KXX78158.1 - 8.2e-14 51.7 1.0 5.5e-12 45.8 0.5 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KXX78158.1 - 1.2e-10 41.1 0.0 0.00047 19.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KXX78158.1 - 8.3e-09 35.1 0.3 1.5e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Auts2 PF15336.1 KXX78158.1 - 0.42 10.5 6.2 0.095 12.7 1.8 1.7 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein GPI-anchored PF10342.4 KXX78159.1 - 5.8e-16 58.7 0.1 5.8e-16 58.7 0.1 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RCR PF12273.3 KXX78160.1 - 1.6e-08 35.1 9.1 2.9e-08 34.3 6.2 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Apolipoprotein PF01442.13 KXX78161.1 - 0.0022 17.5 0.4 0.0028 17.1 0.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KXX78161.1 - 0.0084 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TryThrA_C PF12319.3 KXX78161.1 - 0.082 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal INCENP_N PF12178.3 KXX78161.1 - 0.084 12.4 1.4 8.1 6.0 0.1 2.8 1 1 2 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal Tape_meas_lam_C PF09718.5 KXX78161.1 - 0.12 12.2 0.8 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ING PF12998.2 KXX78161.1 - 0.17 12.1 1.7 0.24 11.6 0.3 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding tRNA-synt_2c PF01411.14 KXX78162.1 - 1.6e-210 700.0 0.1 5.9e-210 698.2 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KXX78162.1 - 3.4e-16 58.8 0.2 9.1e-16 57.4 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PALP PF00291.20 KXX78164.1 - 8.4e-56 189.4 1.4 1.1e-55 189.1 0.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KXX78165.1 - 5.3e-38 130.8 0.0 8.7e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KXX78165.1 - 0.00013 21.0 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Complex1_LYR_2 PF13233.1 KXX78165.1 - 0.22 12.0 1.1 0.56 10.7 0.2 2.0 2 0 0 2 2 2 0 Complex1_LYR-like Pyr_redox_3 PF13738.1 KXX78167.1 - 1.4e-20 74.2 0.0 4.4e-20 72.6 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX78167.1 - 7.2e-11 41.9 0.0 1.8e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KXX78167.1 - 6.5e-10 37.8 0.0 3.1e-09 35.5 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KXX78167.1 - 3.8e-06 26.0 0.0 0.0022 16.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KXX78167.1 - 4.3e-05 23.3 0.0 0.0022 17.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX78167.1 - 0.00018 21.4 0.0 1.3 8.8 0.0 3.0 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 KXX78168.1 - 3.4e-11 42.7 0.2 1.5e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KXX78168.1 - 7.1e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain MBOAT PF03062.14 KXX78169.1 - 5.2e-42 144.0 12.8 5.2e-42 144.0 8.9 1.7 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 KXX78169.1 - 0.094 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cation_efflux PF01545.16 KXX78170.1 - 3.8e-78 262.4 1.2 1.3e-77 260.7 0.8 1.7 1 1 0 1 1 1 1 Cation efflux family Lipase_GDSL_2 PF13472.1 KXX78171.1 - 2.4e-08 34.2 0.0 2.6e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KXX78171.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cu-oxidase_3 PF07732.10 KXX78172.1 - 3.1e-41 139.8 2.6 3.1e-41 139.8 1.8 3.0 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX78172.1 - 2e-37 127.7 8.7 4.5e-37 126.6 0.4 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KXX78172.1 - 1.7e-34 119.0 0.0 4.1e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Catalase PF00199.14 KXX78173.1 - 8.4e-161 534.9 0.2 1.1e-160 534.4 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KXX78173.1 - 3.2e-22 78.1 0.0 6.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KXX78173.1 - 1.5e-08 34.2 0.1 2.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family AAA_5 PF07728.9 KXX78174.1 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX78174.1 - 0.00014 21.8 0.0 0.24 11.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KXX78174.1 - 0.0004 20.2 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KXX78174.1 - 0.00089 19.2 0.3 0.044 13.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Torsin PF06309.6 KXX78174.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA PF00004.24 KXX78174.1 - 0.0022 18.2 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX78174.1 - 0.01 16.6 0.0 0.031 15.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KXX78174.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX78174.1 - 0.09 11.9 0.1 0.69 9.0 0.1 2.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI SET PF00856.23 KXX78175.1 - 1.7e-06 28.4 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SET domain Beta-lactamase PF00144.19 KXX78177.1 - 1e-22 80.6 0.5 1.6e-22 80.0 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase Metallophos_2 PF12850.2 KXX78178.1 - 8.8e-08 32.1 0.0 1.6e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX78178.1 - 4.6e-05 22.9 0.3 0.14 11.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-1_beta_acid PF10587.4 KXX78178.1 - 0.08 13.1 3.0 0.16 12.1 2.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF1308 PF07000.6 KXX78181.1 - 1e-22 80.2 0.0 2.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) NmrA PF05368.8 KXX78182.1 - 8.5e-36 123.3 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX78182.1 - 1.3e-20 74.1 0.0 2e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX78182.1 - 0.00063 19.2 0.0 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX78182.1 - 0.0011 17.6 0.0 0.0023 16.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KXX78182.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KXX78182.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_61 PF03443.9 KXX78183.1 - 1.1e-62 211.6 0.1 1.3e-62 211.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 KXX78184.1 - 5.2e-103 344.9 42.5 6.3e-103 344.6 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX78184.1 - 3.1e-30 105.0 46.7 3.8e-30 104.7 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 KXX78184.1 - 0.018 15.1 0.1 0.018 15.1 0.0 4.6 4 1 0 4 4 4 0 PrgI family protein Arif-1 PF06770.6 KXX78184.1 - 8 5.7 9.8 2.8 7.2 1.3 2.5 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) vMSA PF00695.14 KXX78185.1 - 0.73 8.9 7.6 0.53 9.4 4.4 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus DAO PF01266.19 KXX78186.1 - 3.4e-23 82.1 0.3 8.2e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX78186.1 - 0.00033 20.6 0.1 0.00097 19.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Laminin_II PF06009.7 KXX78186.1 - 0.00035 20.3 3.8 0.00072 19.3 2.6 1.4 1 0 0 1 1 1 1 Laminin Domain II Spc7 PF08317.6 KXX78186.1 - 0.0012 17.5 0.4 0.0022 16.7 0.1 1.4 2 0 0 2 2 2 1 Spc7 kinetochore protein WEMBL PF05701.6 KXX78186.1 - 0.0015 17.1 0.0 0.0021 16.5 0.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF1664 PF07889.7 KXX78186.1 - 0.0026 17.5 3.1 0.0053 16.5 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FliJ PF02050.11 KXX78186.1 - 0.0083 16.1 2.5 0.0083 16.1 1.8 1.7 2 0 0 2 2 1 1 Flagellar FliJ protein Sec8_exocyst PF04048.9 KXX78186.1 - 0.0088 15.6 1.4 0.025 14.2 0.6 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF812 PF05667.6 KXX78186.1 - 0.009 14.5 1.5 0.013 14.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IncA PF04156.9 KXX78186.1 - 0.0094 15.5 0.2 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 IncA protein AKNA PF12443.3 KXX78186.1 - 0.013 15.4 0.6 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor CENP-F_leu_zip PF10473.4 KXX78186.1 - 0.017 14.9 1.2 0.036 13.9 0.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KXX78186.1 - 0.022 14.6 6.5 0.079 12.8 4.3 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Tropomyosin PF00261.15 KXX78186.1 - 0.026 13.6 3.1 0.047 12.7 2.1 1.3 1 0 0 1 1 1 0 Tropomyosin DUF948 PF06103.6 KXX78186.1 - 0.026 14.3 4.6 0.051 13.4 3.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 KXX78186.1 - 0.03 13.8 2.9 0.091 12.3 2.0 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Gp58 PF07902.6 KXX78186.1 - 0.031 12.5 4.8 0.052 11.7 3.3 1.3 1 0 0 1 1 1 0 gp58-like protein ApbA PF02558.11 KXX78186.1 - 0.038 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA COG2 PF06148.6 KXX78186.1 - 0.038 13.8 2.6 0.077 12.8 1.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 KXX78186.1 - 0.043 12.9 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KXX78186.1 - 0.049 13.9 1.2 0.096 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pyr_redox PF00070.22 KXX78186.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fib_alpha PF08702.5 KXX78186.1 - 0.09 12.8 1.4 0.19 11.8 1.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 KXX78186.1 - 0.095 10.4 3.8 0.14 9.8 2.7 1.1 1 0 0 1 1 1 0 Myosin tail DUF4446 PF14584.1 KXX78186.1 - 0.1 12.4 0.3 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Prominin PF05478.6 KXX78186.1 - 0.11 10.0 1.7 0.17 9.4 1.2 1.1 1 0 0 1 1 1 0 Prominin Atg14 PF10186.4 KXX78186.1 - 0.12 11.2 0.7 0.19 10.6 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KXX78186.1 - 0.14 11.2 1.0 0.27 10.2 0.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 KXX78186.1 - 0.2 11.8 2.4 1.6 8.9 1.8 2.3 1 1 0 1 1 1 0 Syntaxin DUF745 PF05335.8 KXX78186.1 - 0.25 10.8 2.6 0.41 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DivIC PF04977.10 KXX78186.1 - 0.3 10.5 5.5 0.7 9.4 3.8 1.6 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.1 KXX78186.1 - 0.35 9.2 1.6 0.51 8.7 1.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2315 PF10231.4 KXX78186.1 - 0.48 10.2 3.6 0.66 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) HR1 PF02185.11 KXX78186.1 - 0.66 9.7 4.4 2.7 7.7 2.0 2.2 1 1 1 2 2 2 0 Hr1 repeat Filament PF00038.16 KXX78186.1 - 0.77 9.1 6.3 0.42 10.0 2.2 1.8 2 0 0 2 2 2 0 Intermediate filament protein COG6 PF06419.6 KXX78186.1 - 1.5 6.8 4.7 2.2 6.3 3.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 NPV_P10 PF05531.7 KXX78186.1 - 2.5 8.4 10.9 2.4 8.4 5.7 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein IFT57 PF10498.4 KXX78186.1 - 3.8 6.1 8.6 0.44 9.2 3.1 1.5 2 0 0 2 2 1 0 Intra-flagellar transport protein 57 DUF1180 PF06679.7 KXX78188.1 - 2 8.2 14.2 0.75 9.6 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HSP20 PF00011.16 KXX78190.1 - 7.3e-17 61.1 0.0 1.8e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4432 PF14486.1 KXX78190.1 - 0.0063 15.1 0.0 0.0088 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4432) Mucin PF01456.12 KXX78190.1 - 4.3 7.1 8.6 8 6.2 6.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein IL11 PF07400.6 KXX78191.1 - 0.051 13.0 0.1 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Interleukin 11 Abhydrolase_6 PF12697.2 KXX78192.1 - 5.8e-31 108.1 3.3 6.8e-31 107.9 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78192.1 - 3.8e-11 42.9 0.4 2.2e-10 40.4 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX78192.1 - 1e-10 41.5 0.0 2e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX78192.1 - 2.8e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase TetR_C_6 PF13977.1 KXX78192.1 - 0.01 15.8 1.3 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional repressor Myb_DNA-bind_6 PF13921.1 KXX78194.1 - 0.00026 21.0 0.1 0.00051 20.0 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain SET PF00856.23 KXX78195.1 - 0.0004 20.7 0.0 0.0016 18.7 0.1 2.1 2 1 0 2 2 2 1 SET domain EHN PF06441.7 KXX78196.1 - 2.9e-27 94.8 0.0 5.6e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KXX78196.1 - 3.3e-08 33.7 0.1 1.1e-07 31.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78196.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M28 PF04389.12 KXX78198.1 - 2.9e-30 105.3 0.0 4.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KXX78198.1 - 3.3e-12 45.9 0.0 7.4e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF506 PF04720.7 KXX78198.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) NUDIX PF00293.23 KXX78199.1 - 1.1e-16 60.7 0.5 3.8e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain SLT PF01464.15 KXX78201.1 - 8.4e-09 34.9 0.5 2.4e-08 33.4 0.3 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 KXX78201.1 - 2.3e-05 23.9 1.6 4.9e-05 22.8 1.1 1.4 1 1 0 1 1 1 1 Lysozyme-like Glyco_hydro_7 PF00840.15 KXX78202.1 - 6.3e-156 519.0 10.0 7.5e-156 518.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_S28 PF05577.7 KXX78203.1 - 1.7e-43 148.7 0.1 1.3e-42 145.9 0.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KXX78203.1 - 1.7e-06 28.1 0.2 7.5e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78203.1 - 0.00072 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 KXX78203.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.16 KXX78203.1 - 0.0016 17.7 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KXX78203.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KXX78203.1 - 0.032 13.6 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative esterase 7TMR-DISM_7TM PF07695.6 KXX78204.1 - 0.0094 15.6 5.2 0.0094 15.6 3.6 2.2 2 0 0 2 2 2 1 7TM diverse intracellular signalling DUF1996 PF09362.5 KXX78205.1 - 2.5e-87 292.4 0.3 3e-87 292.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ComA PF02679.10 KXX78206.1 - 7e-80 267.5 0.0 8.1e-80 267.3 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) ADH_N PF08240.7 KXX78209.1 - 4e-10 39.4 0.0 8.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX78209.1 - 1.1e-09 37.8 1.0 2.2e-09 36.9 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KXX78210.1 - 0.069 12.0 0.1 0.29 9.9 0.0 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain zf-Sec23_Sec24 PF04810.10 KXX78210.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Fungal_trans PF04082.13 KXX78211.1 - 7.6e-12 44.6 0.1 1.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78211.1 - 7.2e-11 41.8 12.2 1.3e-10 41.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAK_assoc PF14380.1 KXX78211.1 - 0.16 12.4 2.1 0.38 11.2 1.5 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal NAD_binding_1 PF00175.16 KXX78212.1 - 8.1e-28 97.1 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KXX78212.1 - 3e-26 91.4 0.0 4.7e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KXX78212.1 - 0.00026 20.9 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain IncA PF04156.9 KXX78213.1 - 0.015 14.9 16.8 0.033 13.7 11.6 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KXX78213.1 - 0.02 12.8 2.9 0.027 12.3 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 KXX78213.1 - 0.031 14.0 10.3 3 7.6 0.3 3.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper AAA_32 PF13654.1 KXX78213.1 - 0.055 12.1 10.5 0.22 10.1 7.3 1.7 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 KXX78213.1 - 0.069 13.2 3.6 0.76 9.9 1.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4611 PF15387.1 KXX78213.1 - 0.071 13.2 5.3 2.7 8.2 0.1 3.1 3 1 1 4 4 3 0 Domain of unknown function (DUF4611) bZIP_1 PF00170.16 KXX78213.1 - 0.079 12.9 13.6 0.36 10.8 1.5 2.9 1 1 0 2 2 2 0 bZIP transcription factor APG6 PF04111.7 KXX78213.1 - 0.087 11.8 15.1 0.056 12.4 9.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KXX78213.1 - 0.17 11.8 17.0 0.15 11.9 5.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 KXX78213.1 - 0.21 11.4 1.6 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF904 PF06005.7 KXX78213.1 - 0.28 11.5 12.1 1.8 8.9 2.0 2.7 2 1 0 3 3 2 0 Protein of unknown function (DUF904) Syntaxin PF00804.20 KXX78213.1 - 0.34 11.0 8.4 0.15 12.2 2.9 2.2 2 0 0 2 2 2 0 Syntaxin Jnk-SapK_ap_N PF09744.4 KXX78213.1 - 0.5 10.3 12.6 1.1 9.2 3.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CCDC155 PF14662.1 KXX78213.1 - 0.95 9.0 16.1 0.056 13.0 5.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KXX78213.1 - 1.4 9.3 11.1 2.2 8.6 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 KXX78213.1 - 1.4 8.0 14.1 3 7.0 5.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.3 KXX78213.1 - 1.5 8.1 11.7 1 8.6 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Brr6_like_C_C PF10104.4 KXX78213.1 - 1.8 8.0 3.8 3.1 7.3 2.6 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF4140 PF13600.1 KXX78213.1 - 2.2 8.8 7.7 3.7 8.0 0.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) KLRAQ PF10205.4 KXX78213.1 - 4.8 7.2 13.0 0.33 10.9 4.0 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein UPF0449 PF15136.1 KXX78213.1 - 5.1 7.3 7.5 5.2 7.3 1.3 2.7 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 2OG-FeII_Oxy PF03171.15 KXX78214.1 - 0.11 12.7 0.0 0.9 9.8 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KXX78214.1 - 0.28 11.7 1.8 1.2 9.6 1.2 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KXX78218.1 - 1.8e-37 128.9 0.0 2.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_GDSL_2 PF13472.1 KXX78220.1 - 4.7e-15 56.1 0.1 6.4e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX78220.1 - 2.8e-12 46.9 0.1 3.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF872 PF05915.7 KXX78221.1 - 0.0035 17.1 1.6 0.0055 16.5 0.0 2.1 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF872) Ribosomal_S5_C PF03719.10 KXX78221.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DUF1772 PF08592.6 KXX78221.1 - 4.8 6.9 10.2 2 8.1 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) CN_hydrolase PF00795.17 KXX78222.1 - 1.6e-23 83.0 0.0 3.6e-23 81.8 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase STE2 PF02116.10 KXX78223.1 - 1.4e-36 126.0 15.8 1.6e-36 125.8 11.0 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 KXX78224.1 - 1.9e-37 127.6 0.1 3.2e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KXX78224.1 - 1.7e-23 82.0 1.0 6.1e-23 80.2 0.0 2.1 2 0 0 2 2 2 1 Vps23 core domain IDO PF01231.13 KXX78225.1 - 4.1e-171 569.0 0.0 4.8e-171 568.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Herpes_IE68 PF02479.11 KXX78228.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein HgmA PF04209.8 KXX78229.1 - 1.9e-170 566.8 0.0 2.4e-170 566.5 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.1 KXX78232.1 - 8.8e-26 90.5 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78232.1 - 1e-12 48.3 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78232.1 - 2.3e-12 47.2 0.0 7.2e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78232.1 - 2.6e-11 43.3 0.0 7.8e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78232.1 - 5e-11 43.1 0.0 2.9e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78232.1 - 4.3e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX78232.1 - 9e-06 24.9 0.0 6e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KXX78232.1 - 4.4e-05 22.7 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 KXX78232.1 - 0.00059 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX78232.1 - 0.0017 17.4 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KXX78232.1 - 0.0044 17.0 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KXX78232.1 - 0.0062 15.9 0.0 0.023 14.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KXX78232.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 KXX78232.1 - 0.033 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KXX78232.1 - 0.049 12.7 0.0 0.094 11.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KXX78232.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KXX78232.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_S15 PF02129.13 KXX78233.1 - 3.8e-42 144.5 0.3 5.4e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KXX78233.1 - 5e-33 114.8 0.0 7.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KXX78233.1 - 3.7e-06 26.9 0.5 6.8e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78233.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CoA_transf_3 PF02515.12 KXX78235.1 - 3.9e-35 120.8 2.4 1.4e-31 109.2 0.4 2.2 2 0 0 2 2 2 2 CoA-transferase family III DEAD PF00270.24 KXX78237.1 - 2.1e-22 79.4 0.1 1.2e-20 73.7 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX78237.1 - 1.7e-19 69.4 0.1 3.3e-17 62.0 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KXX78237.1 - 0.00063 19.6 0.1 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KXX78237.1 - 0.019 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain TMEM154 PF15102.1 KXX78238.1 - 0.42 10.3 2.3 0.31 10.7 0.3 1.7 2 0 0 2 2 2 0 TMEM154 protein family AA_permease PF00324.16 KXX78240.1 - 2.4e-122 408.7 41.5 3e-122 408.4 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX78240.1 - 3.1e-29 101.7 44.7 5.1e-29 101.0 31.0 1.3 1 0 0 1 1 1 1 Amino acid permease Cytochrome-c551 PF10643.4 KXX78240.1 - 0.14 11.4 2.8 0.29 10.3 1.9 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Tmemb_55A PF09788.4 KXX78240.1 - 3.4 6.7 6.0 2.2 7.3 1.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A Rubis-subs-bind PF09273.6 KXX78241.1 - 6.2e-22 77.8 0.0 1.1e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KXX78241.1 - 1.2e-12 48.4 0.0 1.2e-11 45.2 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KXX78241.1 - 2.2e-10 40.2 10.9 3.8e-10 39.4 7.5 1.4 1 0 0 1 1 1 1 MYND finger His_Phos_1 PF00300.17 KXX78243.1 - 6.7e-22 78.2 0.0 8.3e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HET PF06985.6 KXX78244.1 - 9.3e-30 103.6 0.0 1.5e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4064 PF13273.1 KXX78245.1 - 0.00074 19.5 6.4 0.069 13.2 1.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) ODV-E18 PF10717.4 KXX78245.1 - 0.043 13.2 6.5 0.14 11.5 0.1 2.9 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 MARVEL PF01284.18 KXX78245.1 - 0.15 11.8 10.2 0.7 9.6 7.1 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF1282 PF06930.7 KXX78245.1 - 0.41 10.2 12.3 0.63 9.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Acyl_transf_3 PF01757.17 KXX78245.1 - 0.43 9.3 15.3 0.11 11.3 5.4 2.2 1 1 1 2 2 2 0 Acyltransferase family NMN_transporter PF04973.7 KXX78245.1 - 3.6 7.0 10.0 0.21 11.0 3.3 1.5 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Shisa PF13908.1 KXX78245.1 - 4.8 7.3 13.9 6 7.0 0.2 3.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator HET PF06985.6 KXX78246.1 - 1.2e-19 70.8 7.1 2.6e-17 63.2 0.0 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 KXX78246.1 - 5.1e-15 54.6 2.6 2.5e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Ank PF00023.25 KXX78246.1 - 3.9e-07 29.5 0.0 1.4e-06 27.8 0.0 1.9 2 0 0 2 2 1 1 Ankyrin repeat Ank_2 PF12796.2 KXX78246.1 - 2.2e-05 24.7 0.0 6.6e-05 23.1 0.0 1.7 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX78246.1 - 4.9e-05 23.4 0.1 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78246.1 - 5.3e-05 23.0 0.0 0.00017 21.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat APG6 PF04111.7 KXX78246.1 - 0.0056 15.7 12.4 0.0093 15.0 8.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Ank_4 PF13637.1 KXX78246.1 - 0.006 17.0 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Nup160 PF11715.3 KXX78246.1 - 0.071 11.2 0.4 2 6.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF4047 PF13256.1 KXX78246.1 - 0.2 11.6 4.3 0.38 10.7 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) V_ATPase_I PF01496.14 KXX78246.1 - 0.45 8.3 5.5 0.65 7.7 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 KXX78246.1 - 2 7.9 7.5 4.9 6.7 5.2 1.6 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX78246.1 - 2 7.9 13.2 3.4 7.2 9.2 1.3 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 KXX78246.1 - 5.7 6.5 11.4 1.1e+02 2.3 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GMC_oxred_N PF00732.14 KXX78247.1 - 2.7e-43 148.2 0.9 3.5e-43 147.8 0.6 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX78247.1 - 0.0013 17.6 3.5 0.0048 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX78247.1 - 0.014 15.3 0.2 0.05 13.6 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 KXX78248.1 - 1.4e-28 99.0 14.0 5.5e-14 52.2 0.8 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX78248.1 - 2.4e-19 68.0 12.5 3.3e-07 29.7 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KXX78248.1 - 5.1e-18 65.0 11.6 1.9e-08 34.5 0.2 3.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX78248.1 - 2.6e-16 59.2 11.8 5.2e-07 29.7 0.6 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78248.1 - 4.3e-16 57.4 5.7 0.001 19.0 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat MFS_1 PF07690.11 KXX78249.1 - 2e-22 79.3 58.5 1.4e-20 73.2 39.0 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX78249.1 - 0.00062 18.0 24.8 0.00062 18.0 17.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KXX78249.1 - 0.012 15.4 0.5 0.012 15.4 0.3 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Kelch_4 PF13418.1 KXX78250.1 - 7.5e-17 60.8 12.8 2.1e-05 24.1 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KXX78250.1 - 3e-09 36.6 10.1 0.31 11.3 0.0 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_3 PF13415.1 KXX78250.1 - 5.2e-09 36.0 16.9 0.014 15.5 0.0 7.1 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX78250.1 - 6.5e-08 32.3 7.4 0.15 12.0 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KXX78250.1 - 3.3e-06 26.6 7.8 0.47 10.3 0.0 6.1 6 0 0 6 6 6 2 Kelch motif PQQ_3 PF13570.1 KXX78250.1 - 0.0048 17.1 4.3 0.017 15.3 0.2 3.6 4 0 0 4 4 4 1 PQQ-like domain Kelch_1 PF01344.20 KXX78250.1 - 0.017 14.6 8.1 0.077 12.5 0.0 4.1 3 2 1 4 4 4 0 Kelch motif Peptidase_M4_C PF02868.10 KXX78251.1 - 1.7e-40 138.4 0.0 2.8e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 KXX78251.1 - 3.1e-25 89.0 0.3 5.7e-25 88.1 0.2 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 KXX78251.1 - 0.059 12.5 0.4 0.12 11.5 0.3 1.5 1 0 0 1 1 1 0 Peptidase family M13 Senescence PF06911.7 KXX78251.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Senescence-associated protein NACHT PF05729.7 KXX78252.1 - 3e-08 33.5 0.1 0.0038 16.9 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 KXX78252.1 - 0.00041 20.7 0.2 0.068 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KXX78252.1 - 0.0014 18.9 0.0 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 KXX78252.1 - 0.0014 18.7 0.0 0.013 15.5 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX78252.1 - 0.0022 18.8 0.2 0.015 16.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KXX78252.1 - 0.0043 16.5 0.4 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Seryl_tRNA_N PF02403.17 KXX78252.1 - 0.0049 16.8 2.1 0.045 13.7 1.3 2.2 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AAA_29 PF13555.1 KXX78252.1 - 0.0049 16.3 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KXX78252.1 - 0.0053 17.0 0.3 0.058 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX78252.1 - 0.0061 16.5 1.7 0.15 12.0 0.0 3.2 2 2 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KXX78252.1 - 0.0096 15.1 0.0 0.96 8.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KXX78252.1 - 0.012 15.3 0.1 0.8 9.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase IF2_N PF04760.10 KXX78252.1 - 0.035 13.7 1.4 0.12 12.0 0.1 2.5 2 1 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NTPase_1 PF03266.10 KXX78252.1 - 0.044 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Mnd1 PF03962.10 KXX78252.1 - 0.046 13.3 1.7 0.051 13.2 0.4 1.7 2 0 0 2 2 2 0 Mnd1 family RNA_helicase PF00910.17 KXX78252.1 - 0.046 13.8 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 KXX78252.1 - 0.053 12.9 0.0 0.17 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX78252.1 - 0.067 13.0 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KXX78252.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 KXX78252.1 - 0.3 10.9 4.1 0.52 10.1 2.8 1.3 1 0 0 1 1 1 0 Tropomyosin like AATF-Che1 PF13339.1 KXX78252.1 - 1.5 8.9 4.6 4.9 7.3 1.0 2.4 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Gaa1 PF04114.9 KXX78253.1 - 1.2e-96 324.4 7.1 4.8e-96 322.4 4.9 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 KXX78253.1 - 6e-13 49.0 10.1 6e-13 49.0 7.0 3.6 3 2 1 4 4 4 1 Rhomboid family Gemini_mov PF01708.11 KXX78253.1 - 6.2 6.4 0.0 6.2 6.4 0.0 3.3 4 0 0 4 4 4 0 Geminivirus putative movement protein PCI PF01399.22 KXX78254.1 - 1.5e-10 41.3 0.0 4.3e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 PCI domain zf-C2H2_jaz PF12171.3 KXX78255.1 - 1.7e-09 37.4 0.5 3.5e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KXX78255.1 - 0.021 14.3 0.2 0.042 13.3 0.1 1.6 2 0 0 2 2 2 0 U1 zinc finger Aconitase PF00330.15 KXX78256.1 - 3.2e-173 576.4 0.0 7.1e-173 575.3 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KXX78256.1 - 4.8e-45 152.8 0.0 8.8e-45 152.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain N6-adenineMlase PF10237.4 KXX78257.1 - 1.1e-56 190.9 0.0 1.5e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UCH PF00443.24 KXX78258.1 - 1.4e-57 194.8 3.2 2.1e-57 194.2 2.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX78258.1 - 4.7e-37 128.0 1.1 8.7e-37 127.1 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KXX78258.1 - 0.0012 18.9 0.6 0.0012 18.9 0.4 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein NmrA PF05368.8 KXX78259.1 - 1.4e-17 63.7 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX78259.1 - 5.9e-17 62.2 0.0 8.9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX78259.1 - 5.6e-16 58.7 0.1 1.3e-15 57.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX78259.1 - 1.2e-11 43.8 0.1 2.1e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KXX78259.1 - 2.1e-08 33.3 0.0 9.4e-07 27.9 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KXX78259.1 - 1.4e-05 24.1 0.4 0.0017 17.2 0.3 2.9 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 KXX78259.1 - 2.6e-05 24.1 0.0 0.00023 21.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KXX78259.1 - 8.9e-05 21.5 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KXX78259.1 - 0.00039 20.1 0.1 0.13 11.8 0.0 2.7 3 0 0 3 3 3 1 KR domain Saccharop_dh PF03435.13 KXX78259.1 - 0.0037 16.2 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 KXX78259.1 - 0.049 13.4 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DDE_Tnp_1_3 PF13612.1 KXX78259.1 - 0.079 12.6 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Methyltransf_11 PF08241.7 KXX78260.1 - 4e-08 33.6 0.0 6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78260.1 - 1.3e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78260.1 - 2.1e-05 25.0 0.0 3.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78260.1 - 0.0026 18.1 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX78260.1 - 0.004 17.1 0.0 0.0085 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78260.1 - 0.05 13.9 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KXX78260.1 - 0.092 12.4 0.0 0.43 10.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Lactamase_B PF00753.22 KXX78261.1 - 1.8e-25 89.7 5.1 2.6e-25 89.2 3.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KXX78261.1 - 3.4e-06 26.7 0.3 5e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KXX78261.1 - 0.03 14.0 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ytp1 PF10355.4 KXX78262.1 - 1.4e-112 375.3 6.1 2e-112 374.7 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KXX78262.1 - 3.8e-34 116.4 1.5 3.8e-34 116.4 1.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF3481 PF11980.3 KXX78262.1 - 0.18 11.6 0.5 0.94 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Ca_hom_mod PF14798.1 KXX78262.1 - 0.79 8.6 2.2 0.81 8.6 0.1 1.9 2 0 0 2 2 2 0 Calcium homeostasis modulator Metallopep PF12044.3 KXX78263.1 - 3e-167 556.3 0.0 3.7e-167 556.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KXX78263.1 - 2.6e-07 30.5 0.0 4.2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.19 KXX78263.1 - 0.024 14.3 0.8 0.054 13.2 0.6 1.6 1 1 0 1 1 1 0 Matrixin W2 PF02020.13 KXX78264.1 - 7.9e-17 60.9 2.7 2.9e-16 59.2 1.9 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KXX78264.1 - 1.6e-09 36.8 9.5 0.00068 19.0 0.6 5.5 2 1 3 6 6 6 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KXX78264.1 - 1.3e-05 24.6 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase GAT PF03127.9 KXX78264.1 - 0.021 14.7 0.5 0.055 13.4 0.4 1.6 1 0 0 1 1 1 0 GAT domain NTP_transf_3 PF12804.2 KXX78264.1 - 0.038 14.0 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KXX78264.1 - 0.067 12.7 6.7 0.52 9.9 0.5 3.5 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Whi5 PF08528.6 KXX78265.1 - 2.2e-08 33.4 0.3 2.2e-08 33.4 0.2 1.7 2 0 0 2 2 2 1 Whi5 like SF-assemblin PF06705.6 KXX78265.1 - 0.052 12.6 0.4 0.075 12.1 0.3 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF1839 PF08893.5 KXX78265.1 - 0.11 11.3 0.3 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) I-set PF07679.11 KXX78266.1 - 4.6e-05 23.1 0.0 8.5 6.3 0.0 5.6 5 0 0 5 5 5 1 Immunoglobulin I-set domain DUF1918 PF08940.6 KXX78266.1 - 0.0053 16.0 0.7 18 4.7 0.0 5.0 5 0 0 5 5 5 2 Domain of unknown function (DUF1918) SKG6 PF08693.5 KXX78267.1 - 0.003 16.8 2.9 0.003 16.8 2.0 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KXX78267.1 - 0.23 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Extensin_2 PF04554.8 KXX78269.1 - 0.26 11.1 37.3 0.44 10.4 25.9 1.5 1 1 0 1 1 1 0 Extensin-like region DUF2410 PF10307.4 KXX78270.1 - 5.7e-82 273.8 0.0 8.3e-82 273.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) PAS_9 PF13426.1 KXX78271.1 - 3.8e-24 85.0 0.0 6.5e-17 61.8 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KXX78271.1 - 2e-19 69.4 0.0 3.8e-10 39.7 0.0 4.0 4 0 0 4 4 4 3 PAS fold PAS PF00989.19 KXX78271.1 - 7.5e-14 51.4 0.1 2.6e-06 27.1 0.0 4.3 4 0 0 4 4 4 2 PAS fold GATA PF00320.22 KXX78271.1 - 1.3e-13 50.0 7.9 1.3e-13 50.0 5.5 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_11 PF14598.1 KXX78271.1 - 2.9e-07 30.4 0.0 0.00023 21.0 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KXX78271.1 - 7.1e-07 29.2 0.0 0.14 12.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 KXX78271.1 - 0.099 12.5 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 PAS domain Peptidase_C14 PF00656.17 KXX78272.1 - 4.9e-73 245.8 0.0 5.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KXX78272.1 - 0.14 12.0 0.5 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain HSF_DNA-bind PF00447.12 KXX78273.1 - 5.2e-38 129.3 0.3 9.9e-38 128.4 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KXX78273.1 - 3.1e-23 81.9 0.6 5.5e-23 81.1 0.4 1.4 1 0 0 1 1 1 1 Response regulator receiver domain IncA PF04156.9 KXX78273.1 - 0.024 14.2 1.6 0.038 13.5 1.1 1.2 1 0 0 1 1 1 0 IncA protein CENP-H PF05837.7 KXX78273.1 - 0.045 13.9 6.7 0.08 13.1 4.6 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 KXX78273.1 - 0.12 12.7 1.6 0.26 11.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) tRNA-synt_2b PF00587.20 KXX78274.1 - 1.4e-43 148.4 0.3 2.3e-43 147.7 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KXX78274.1 - 1.6e-20 72.8 0.2 3.1e-20 71.9 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KXX78274.1 - 9.7e-13 47.7 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KXX78274.1 - 7e-11 41.7 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain Pro-NT_NN PF07421.6 KXX78274.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Transglut_core2 PF13369.1 KXX78275.1 - 4e-15 55.6 0.0 7.6e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box PF00646.28 KXX78275.1 - 9.1e-08 31.5 0.7 3e-07 29.9 0.5 2.0 1 0 0 1 1 1 1 F-box domain YccV-like PF08755.6 KXX78275.1 - 2.2e-06 27.5 0.4 1.8e-05 24.5 0.2 2.4 3 0 0 3 3 3 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 KXX78275.1 - 2.7e-06 27.0 1.7 6.5e-06 25.7 1.1 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_C12 PF01088.16 KXX78276.1 - 6.7e-57 192.1 0.0 2.2e-56 190.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CDP-OH_P_transf PF01066.16 KXX78277.1 - 3.6e-14 52.8 2.2 6.9e-14 51.9 1.5 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase zf-H2C2_2 PF13465.1 KXX78278.1 - 1.9e-10 40.5 12.6 1.9e-05 24.7 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KXX78278.1 - 4.4e-10 39.2 12.5 2.1e-05 24.5 3.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX78278.1 - 1.1e-06 28.5 9.2 0.00021 21.3 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KXX78278.1 - 4.9e-06 26.5 1.5 2.1e-05 24.5 1.0 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX78278.1 - 6.5e-05 22.9 5.7 0.00013 22.0 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KXX78278.1 - 0.00072 19.3 8.3 0.0042 16.9 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger PAP2 PF01569.16 KXX78278.1 - 0.022 14.4 0.6 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 PAP2 superfamily zf-C2H2_2 PF12756.2 KXX78278.1 - 0.039 14.0 1.3 0.039 14.0 0.9 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KXX78278.1 - 0.48 10.1 3.8 6.3 6.5 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 KXX78278.1 - 3.1 7.6 6.0 22 4.9 4.2 2.1 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KXX78278.1 - 9.8 6.6 8.6 4.9 7.5 0.9 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain HAD PF12710.2 KXX78279.1 - 5.8e-13 49.4 0.0 8.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KXX78279.1 - 0.0026 16.9 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase_3 PF08282.7 KXX78279.1 - 0.0074 15.9 0.4 0.041 13.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX78279.1 - 0.03 14.7 0.0 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KXX78279.1 - 0.051 12.8 0.0 0.1 11.9 0.0 1.4 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TFIIF_beta PF02270.10 KXX78280.1 - 1.6e-72 244.6 5.7 1.9e-72 244.3 3.9 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit OGG_N PF07934.7 KXX78281.1 - 2.2e-35 121.1 0.0 4.3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KXX78281.1 - 1.2e-16 60.8 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KXX78281.1 - 0.00036 20.0 0.0 0.00093 18.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HECT_2 PF09814.4 KXX78282.1 - 6.3e-68 229.0 0.2 7.2e-68 228.8 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-ribbon_3 PF13248.1 KXX78282.1 - 0.012 14.7 1.6 0.48 9.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain SF3b1 PF08920.5 KXX78283.1 - 1.3e-34 119.3 4.4 1.6e-34 118.9 0.2 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KXX78283.1 - 7.9e-15 54.9 3.3 0.01 16.1 0.0 7.2 6 3 2 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 KXX78283.1 - 5.1e-11 42.7 0.7 0.34 11.4 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.17 KXX78283.1 - 1.3e-10 40.4 8.4 0.95 9.7 0.0 9.4 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KXX78283.1 - 8.8e-06 26.0 0.3 0.65 10.4 0.0 5.2 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region UPF0236 PF06782.6 KXX78283.1 - 0.00026 19.5 0.0 0.00057 18.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) Adaptin_N PF01602.15 KXX78283.1 - 0.00068 18.0 0.1 0.16 10.2 0.0 3.0 2 2 0 3 3 3 1 Adaptin N terminal region NUC173 PF08161.7 KXX78283.1 - 0.0093 15.3 0.3 5.8 6.2 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 KXX78283.1 - 0.0094 15.3 0.1 1.3 8.3 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal Rax2 PF12768.2 KXX78285.1 - 1.6e-92 309.7 1.6 8.5e-84 281.0 0.0 5.0 4 1 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_4 PF13418.1 KXX78285.1 - 0.00091 18.9 5.1 2.1 8.1 0.1 4.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KXX78285.1 - 0.0074 16.4 16.2 0.049 13.8 0.3 5.2 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KXX78285.1 - 0.011 15.3 1.9 1.6 8.3 0.0 4.0 3 0 0 3 3 3 0 Kelch motif Syndecan PF01034.15 KXX78285.1 - 0.16 11.6 0.3 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain SNase PF00565.12 KXX78286.1 - 9.8e-23 80.4 0.0 1.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF2360 PF10152.4 KXX78287.1 - 0.058 13.6 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Sel1 PF08238.7 KXX78288.1 - 4e-22 78.1 3.7 5.1e-07 30.1 0.0 3.8 3 0 0 3 3 3 3 Sel1 repeat P34-Arc PF04045.9 KXX78291.1 - 3.5e-100 334.2 0.2 4.3e-100 333.9 0.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Radical_SAM PF04055.16 KXX78291.1 - 0.14 12.3 0.9 2.2 8.4 0.0 2.2 2 1 1 3 3 3 0 Radical SAM superfamily WD40 PF00400.27 KXX78292.1 - 3.1e-65 213.8 18.4 2e-08 33.7 0.1 12.7 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 KXX78292.1 - 7.8e-19 67.6 0.7 1.6e-18 66.5 0.5 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 KXX78292.1 - 0.00018 20.4 2.7 1.4 7.5 0.0 5.6 2 2 2 6 6 6 1 Nup133 N terminal like Nup160 PF11715.3 KXX78292.1 - 0.00035 18.8 4.2 0.0048 15.1 0.2 4.0 2 2 0 4 4 4 1 Nucleoporin Nup120/160 eIF2A PF08662.6 KXX78292.1 - 0.005 16.5 0.2 0.31 10.7 0.0 3.8 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KXX78292.1 - 0.0067 14.7 0.0 0.076 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) zf-CCCH PF00642.19 KXX78293.1 - 3.1e-10 39.4 26.0 1.4e-05 24.5 0.7 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HeLo PF14479.1 KXX78293.1 - 0.03 14.0 1.1 0.051 13.3 0.7 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Pyr_redox_3 PF13738.1 KXX78294.1 - 1.1e-26 94.1 0.0 2.2e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KXX78294.1 - 9.7e-14 50.4 0.0 2e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KXX78294.1 - 2.6e-11 43.0 0.0 4.7e-09 35.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KXX78294.1 - 3.2e-07 30.2 0.0 7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX78294.1 - 0.00012 21.9 0.7 0.00031 20.5 0.0 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX78294.1 - 0.00022 21.1 0.0 0.0013 18.6 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX78294.1 - 0.0013 17.8 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KXX78294.1 - 0.019 13.8 0.1 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KXX78294.1 - 0.02 13.3 0.1 0.032 12.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KXX78294.1 - 0.039 12.8 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase LBR_tudor PF09465.5 KXX78294.1 - 0.072 12.7 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain RRM_1 PF00076.17 KXX78295.1 - 1.3e-25 88.8 0.3 1e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX78295.1 - 6.9e-19 67.6 0.0 3.3e-06 26.9 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX78295.1 - 4.2e-10 39.3 0.2 0.00045 20.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KXX78295.1 - 0.092 12.8 0.1 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) DUF4411 PF14367.1 KXX78295.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Ribosomal_S13_N PF08069.7 KXX78296.1 - 3.5e-30 103.6 0.1 7e-30 102.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KXX78296.1 - 2.8e-23 81.4 0.0 4.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KXX78296.1 - 0.02 14.6 0.1 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain VRR_NUC PF08774.6 KXX78297.1 - 4e-18 65.2 0.0 8.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain DUF4551 PF15087.1 KXX78298.1 - 4.6 5.4 6.6 5.9 5.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TCTP PF00838.12 KXX78299.1 - 0.18 11.7 0.7 0.32 10.9 0.1 1.6 2 0 0 2 2 2 0 Translationally controlled tumour protein HET PF06985.6 KXX78300.1 - 2.4e-27 95.7 0.0 5.5e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Epimerase PF01370.16 KXX78302.1 - 5.3e-18 65.3 0.0 6.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX78302.1 - 8.1e-08 31.4 0.0 1.6e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KXX78302.1 - 3.9e-07 30.1 0.0 6.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KXX78302.1 - 1.2e-06 27.4 0.0 1.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KXX78302.1 - 8.9e-06 24.7 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KXX78302.1 - 8.7e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1680 PF07944.7 KXX78303.1 - 3.8e-137 457.7 0.0 4.4e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 KXX78304.1 - 6.6e-50 165.2 28.9 2.3e-13 49.4 2.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 KXX78304.1 - 2.1e-25 89.2 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KXX78304.1 - 4.9e-07 28.2 4.2 0.14 10.2 0.1 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 KXX78304.1 - 5.9e-05 22.3 9.8 0.53 9.3 0.1 4.2 1 1 3 4 4 4 3 Neuroblastoma-amplified sequence, N terminal DUF676 PF05057.9 KXX78304.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KXX78304.1 - 0.0047 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KXX78304.1 - 0.0052 16.7 0.0 0.022 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Plectin PF00681.15 KXX78304.1 - 0.014 14.8 0.0 31 4.1 0.0 4.0 4 0 0 4 4 4 0 Plectin repeat PGAP1 PF07819.8 KXX78304.1 - 0.03 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_19 PF13245.1 KXX78304.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 KXX78304.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 HET PF06985.6 KXX78305.1 - 1e-18 67.8 0.0 2.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.23 KXX78306.1 - 3.6e-08 33.8 0.0 1.2e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_14 PF13428.1 KXX78306.1 - 0.04 14.5 3.1 8.2 7.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78306.1 - 0.19 12.4 6.0 0.57 10.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NYN PF01936.13 KXX78307.1 - 1.2e-31 110.0 0.0 2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 KXX78307.1 - 4.3e-17 61.6 0.0 7.2e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DUF2443 PF10398.4 KXX78308.1 - 0.12 12.1 0.3 0.37 10.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) RTA1 PF04479.8 KXX78309.1 - 1.7e-33 116.0 6.9 1.7e-33 116.0 4.8 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 KXX78309.1 - 3.7 6.4 10.3 20 4.0 6.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CBM_1 PF00734.13 KXX78310.1 - 4.3e-10 39.0 12.3 1.4e-09 37.4 8.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Esterase_phd PF10503.4 KXX78311.1 - 2.3e-26 92.4 0.2 3.1e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX78311.1 - 1.5e-12 47.1 0.4 2.2e-12 46.6 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX78311.1 - 6.1e-09 35.7 0.1 7.8e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX78311.1 - 3.8e-07 30.2 0.0 7.3e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX78311.1 - 8.6e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX78311.1 - 4.9e-06 25.5 0.1 7.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 KXX78311.1 - 1.2e-05 24.8 0.1 1.9e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KXX78311.1 - 3.3e-05 23.5 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KXX78311.1 - 0.00087 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KXX78311.1 - 0.0023 17.6 0.2 0.0035 17.0 0.1 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 KXX78311.1 - 0.0045 16.6 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S10 PF00450.17 KXX78311.1 - 0.0053 15.9 0.3 0.34 10.0 0.1 2.0 2 0 0 2 2 2 1 Serine carboxypeptidase DUF2920 PF11144.3 KXX78311.1 - 0.0088 15.1 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) DLH PF01738.13 KXX78311.1 - 0.022 14.0 0.2 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 KXX78311.1 - 0.054 11.9 0.1 0.086 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Eno-Rase_NADH_b PF12242.3 KXX78311.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase His_Phos_1 PF00300.17 KXX78312.1 - 6.3e-24 84.8 0.0 4.9e-23 81.9 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_43 PF04616.9 KXX78313.1 - 3.2e-47 160.9 2.6 3.7e-47 160.7 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_3 PF07859.8 KXX78314.1 - 3.7e-38 131.2 0.1 1.6e-37 129.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX78314.1 - 0.0099 14.5 0.3 0.042 12.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KXX78314.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family SUFU PF05076.8 KXX78314.1 - 0.034 13.7 0.0 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) Sulfotransfer_3 PF13469.1 KXX78317.1 - 0.00021 22.2 5.5 0.00021 22.2 3.8 1.7 2 0 0 2 2 2 1 Sulfotransferase family DNA_binding_1 PF01035.15 KXX78318.1 - 4.5e-19 67.9 0.7 2.1e-18 65.8 0.5 1.9 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MFS_1 PF07690.11 KXX78320.1 - 2.1e-14 53.0 28.8 2.1e-14 53.0 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KXX78320.1 - 2.2e-11 43.4 4.9 2.2e-11 43.4 3.4 2.3 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 AcetylCoA_hydro PF02550.10 KXX78321.1 - 1.9e-48 164.8 0.0 2.8e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KXX78321.1 - 5.3e-37 126.8 0.0 8e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RasGEF PF00617.14 KXX78322.1 - 2.5e-54 183.8 0.0 4.9e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KXX78322.1 - 1.1e-18 67.1 0.0 5.3e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 KXX78322.1 - 3.3e-06 26.5 0.0 7.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX78322.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Barstar PF01337.13 KXX78322.1 - 0.15 11.8 0.2 0.84 9.5 0.1 2.3 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Exo_endo_phos PF03372.18 KXX78323.1 - 3.9e-07 30.2 2.4 5.5e-07 29.7 1.7 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 KXX78323.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain AIM24 PF01987.12 KXX78324.1 - 5.8e-50 169.7 0.0 7.2e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 KXX78324.1 - 0.028 14.9 0.1 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Cutinase PF01083.17 KXX78325.1 - 2.8e-53 180.3 9.4 3.5e-53 179.9 6.5 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 KXX78325.1 - 1.9e-09 37.0 13.2 1.9e-09 37.0 9.1 4.3 3 1 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 KXX78325.1 - 5.1e-06 26.5 0.0 6.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KXX78325.1 - 2.2e-05 23.9 0.1 3.7e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KXX78325.1 - 0.00022 20.8 0.1 0.00045 19.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX78325.1 - 0.0024 17.6 0.7 0.0065 16.2 0.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Secretin_N PF03958.12 KXX78325.1 - 0.039 14.1 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain VirJ PF06057.6 KXX78325.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Toxin_7 PF05980.7 KXX78325.1 - 1.4 9.0 17.7 0.24 11.4 6.9 2.7 2 0 0 2 2 2 0 Toxin 7 ABC_membrane PF00664.18 KXX78326.1 - 3.4e-37 128.3 13.0 4.2e-37 128.0 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KXX78326.1 - 8.5e-33 113.5 0.0 1.3e-31 109.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 KXX78326.1 - 4.2e-06 26.8 0.0 2.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KXX78326.1 - 1.1e-05 25.5 0.0 0.048 13.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KXX78326.1 - 2.8e-05 23.4 0.0 0.0082 15.3 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 KXX78326.1 - 0.00015 21.6 0.0 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX78326.1 - 0.00034 21.4 0.0 0.00065 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX78326.1 - 0.00037 20.6 0.0 0.004 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KXX78326.1 - 0.00087 18.5 0.0 0.002 17.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KXX78326.1 - 0.0021 17.5 0.0 0.0073 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KXX78326.1 - 0.0043 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KXX78326.1 - 0.01 15.9 0.0 0.11 12.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KXX78326.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KXX78326.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KXX78326.1 - 0.026 14.8 0.0 0.085 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KXX78326.1 - 0.028 13.5 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KXX78326.1 - 0.032 13.9 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KXX78326.1 - 0.034 14.0 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KXX78326.1 - 0.036 14.5 0.0 0.082 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 KXX78326.1 - 0.047 13.3 0.1 0.25 10.9 0.0 2.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 KXX78326.1 - 0.051 12.9 0.2 0.16 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KXX78326.1 - 0.061 12.8 0.2 1.2 8.6 0.0 2.8 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 KXX78326.1 - 0.072 12.7 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 KXX78326.1 - 0.074 12.9 0.4 0.69 9.8 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF3539 PF12058.3 KXX78327.1 - 6.2 6.7 11.8 0.72 9.7 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3539) NUDIX_4 PF14815.1 KXX78328.1 - 3.1e-17 62.0 0.0 6.5e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 KXX78328.1 - 7.8e-17 61.5 0.0 3.3e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KXX78328.1 - 0.0008 18.9 0.1 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif FeS PF04060.8 KXX78328.1 - 0.017 14.6 1.6 0.047 13.2 1.1 1.8 1 0 0 1 1 1 0 Putative Fe-S cluster ACPS PF01648.15 KXX78330.1 - 5.9e-15 55.0 0.0 1e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PHP PF02811.14 KXX78331.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 PHP domain AA_permease_2 PF13520.1 KXX78332.1 - 3.3e-53 180.7 45.2 4e-53 180.4 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX78332.1 - 1.7e-16 59.6 38.4 2.3e-16 59.2 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease PCDO_beta_N PF12391.3 KXX78333.1 - 0.21 11.0 1.5 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF3433 PF11915.3 KXX78334.1 - 4.6e-07 29.8 0.3 4.6e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Asp PF00026.18 KXX78335.1 - 6e-59 199.8 0.0 1.4e-58 198.6 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX78335.1 - 7.3e-07 29.2 0.0 5.6e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KXX78335.1 - 0.0023 17.4 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal DHDPS PF00701.17 KXX78336.1 - 2.3e-30 105.1 0.0 3.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Kinesin PF00225.18 KXX78337.1 - 1.7e-78 263.7 0.0 2.4e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TFIIA PF03153.8 KXX78337.1 - 0.81 9.5 13.0 1.4 8.7 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 KXX78337.1 - 1.6 9.0 12.5 0.48 10.7 5.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP2 PF01569.16 KXX78338.1 - 2.5e-20 72.4 8.2 2.5e-20 72.4 5.7 1.7 2 0 0 2 2 2 1 PAP2 superfamily YbjM PF11045.3 KXX78338.1 - 0.051 13.3 0.6 0.051 13.3 0.4 2.4 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae PAP2_C PF14360.1 KXX78338.1 - 3 8.1 8.2 0.53 10.6 0.8 3.0 3 0 0 3 3 3 0 PAP2 superfamily C-terminal E1-E2_ATPase PF00122.15 KXX78339.1 - 1.5e-58 197.6 1.1 3.6e-58 196.3 0.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX78339.1 - 6.4e-46 156.1 1.2 6.4e-46 156.1 0.8 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX78339.1 - 5.2e-30 105.4 0.0 2.6e-29 103.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX78339.1 - 2.6e-19 68.9 0.0 5.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KXX78339.1 - 6e-14 52.6 0.0 1.6e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX78339.1 - 9.1e-07 28.7 0.4 2.1e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX78339.1 - 3.2e-06 26.4 0.2 1.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus FAD_binding_4 PF01565.18 KXX78340.1 - 1.3e-17 63.5 1.9 2.2e-17 62.8 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX78340.1 - 5.8e-11 42.1 0.0 1.5e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX78340.1 - 0.17 10.9 0.1 0.31 10.1 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.20 KXX78342.1 - 1.6e-15 57.4 0.0 2.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX78342.1 - 1.8e-09 37.5 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX78342.1 - 2.3e-06 27.2 0.1 4.9e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX78342.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KXX78342.1 - 0.013 15.5 0.7 0.026 14.5 0.5 1.7 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX78342.1 - 0.019 13.8 0.6 0.023 13.6 0.1 1.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KXX78342.1 - 0.021 14.8 0.2 0.046 13.8 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 KXX78342.1 - 0.066 12.0 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 KXX78342.1 - 0.11 12.3 0.4 0.26 11.2 0.2 1.7 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.13 KXX78343.1 - 1.4e-11 43.7 0.1 2.5e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain XFP_N PF09364.5 KXX78344.1 - 2.3e-150 500.4 0.0 3e-150 499.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KXX78344.1 - 3.8e-68 228.5 0.0 6.8e-68 227.7 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KXX78344.1 - 6.1e-65 218.4 0.0 9.6e-65 217.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 KXX78344.1 - 0.0036 16.8 0.1 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Hexapep PF00132.19 KXX78345.1 - 6.2e-08 31.8 10.9 0.0015 17.9 3.5 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KXX78345.1 - 2.1e-07 30.3 8.8 0.0069 15.9 0.1 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KXX78345.1 - 0.0014 18.5 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1996 PF09362.5 KXX78347.1 - 2e-86 289.5 3.0 2.8e-86 288.9 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) DUF1190 PF06693.6 KXX78348.1 - 0.095 12.7 2.0 0.12 12.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Myco_19_kDa PF05481.7 KXX78348.1 - 0.28 11.0 2.9 0.36 10.6 2.0 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen p450 PF00067.17 KXX78350.1 - 8.9e-47 159.6 0.0 1.1e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FNIP_M PF14637.1 KXX78350.1 - 0.097 12.2 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain SGL PF08450.7 KXX78351.1 - 5.9e-25 88.0 0.2 1.5e-24 86.6 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KXX78351.1 - 4.4e-06 26.6 0.0 4e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 KXX78351.1 - 1.1e-05 25.1 2.7 0.015 15.2 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Arylesterase PF01731.15 KXX78351.1 - 8.9e-05 22.4 0.4 0.0029 17.5 0.0 2.9 3 0 0 3 3 3 1 Arylesterase SBBP PF06739.6 KXX78351.1 - 0.012 15.4 1.0 0.72 9.6 0.1 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Glyco_hydro_61 PF03443.9 KXX78352.1 - 1.2e-54 185.4 0.0 1.5e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S8 PF00082.17 KXX78354.1 - 7e-19 68.0 0.0 1.5e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family TPR_12 PF13424.1 KXX78354.1 - 1 9.3 5.3 0.82 9.6 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.6 KXX78355.1 - 1.8e-29 102.6 0.0 3.7e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRTP PF01366.13 KXX78356.1 - 0.034 12.1 0.1 0.055 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ABM PF03992.11 KXX78356.1 - 0.13 12.3 1.8 22 5.2 0.0 3.2 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase AAA PF00004.24 KXX78357.1 - 8e-16 58.4 0.0 5.8e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX78357.1 - 5.4e-05 24.0 0.0 0.00017 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX78357.1 - 0.0014 18.8 0.0 0.0039 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX78357.1 - 0.0018 18.2 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 KXX78357.1 - 0.0026 17.2 0.2 0.04 13.3 0.2 2.2 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KXX78357.1 - 0.0041 17.2 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX78357.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX78357.1 - 0.0094 15.6 0.1 0.069 12.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KXX78357.1 - 0.023 14.2 1.8 0.032 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KXX78357.1 - 0.073 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KXX78357.1 - 0.085 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX78357.1 - 0.15 11.2 0.1 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KXX78357.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase adh_short PF00106.20 KXX78358.1 - 1.9e-22 79.9 5.6 2e-21 76.6 3.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX78358.1 - 1.1e-20 74.4 1.4 1.8e-20 73.7 1.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX78358.1 - 9.7e-08 31.8 0.6 9.7e-08 31.8 0.4 2.2 1 1 1 2 2 2 1 KR domain Shikimate_DH PF01488.15 KXX78358.1 - 2.2e-05 24.5 0.2 5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 KXX78358.1 - 0.0022 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KXX78358.1 - 0.0034 17.3 2.6 0.045 13.7 0.2 2.4 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX78358.1 - 0.0064 15.4 0.1 0.0092 14.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KXX78358.1 - 0.014 15.6 0.5 0.08 13.1 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.21 KXX78358.1 - 0.04 13.4 0.2 0.09 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 KXX78358.1 - 0.076 13.4 0.8 0.26 11.6 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.3 KXX78358.1 - 0.1 12.4 0.2 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BEX PF04538.7 KXX78358.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family Chitin_synth_2 PF03142.10 KXX78359.1 - 1.9e-294 976.9 0.8 2e-294 976.9 0.1 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KXX78359.1 - 1.1e-18 67.6 3.7 5.8e-18 65.2 2.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX78359.1 - 1.3e-14 54.5 0.0 2.2e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KXX78359.1 - 7.5e-13 48.0 0.0 5.5e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KXX78359.1 - 0.00016 20.9 0.0 0.0009 18.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX78359.1 - 0.033 13.8 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 RNB PF00773.14 KXX78360.1 - 6.1e-61 206.4 0.0 9.3e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain Prenyltransf PF01255.14 KXX78362.1 - 2.5e-08 33.3 0.0 3.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase SWIRM PF04433.12 KXX78363.1 - 3.1e-16 59.2 0.1 4.1e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain F-box-like PF12937.2 KXX78364.1 - 6e-09 35.4 0.5 1.2e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX78364.1 - 5.1e-06 25.9 1.2 9.5e-06 25.1 0.8 1.4 1 0 0 1 1 1 1 F-box domain Grp1_Fun34_YaaH PF01184.14 KXX78365.1 - 3.9e-21 75.3 25.4 1.2e-20 73.7 17.6 1.6 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Met_10 PF02475.11 KXX78366.1 - 7.2e-75 250.9 0.0 9.5e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KXX78366.1 - 0.0043 17.0 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78366.1 - 0.0079 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sec10 PF07393.6 KXX78367.1 - 4.5e-228 758.9 4.9 5.5e-228 758.7 3.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 BTG PF07742.7 KXX78367.1 - 0.15 11.5 0.4 10 5.6 0.0 3.3 2 1 1 3 3 3 0 BTG family K_channel_TID PF07941.6 KXX78367.1 - 0.16 12.2 5.3 0.44 10.8 3.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.27 KXX78368.1 - 3.7e-09 36.1 2.6 3.2e-06 26.8 0.1 4.4 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF2415 PF10313.4 KXX78368.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) RRN3 PF05327.6 KXX78368.1 - 7.8 4.4 9.7 11 4.0 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_gE PF02480.11 KXX78369.1 - 0.012 13.9 0.0 0.026 12.8 0.0 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KXX78369.1 - 0.02 14.1 0.9 0.02 14.1 0.6 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Granulin PF00396.13 KXX78369.1 - 0.068 13.2 4.7 0.14 12.2 0.8 2.6 2 0 0 2 2 2 0 Granulin DUF347 PF03988.7 KXX78369.1 - 0.096 12.5 2.3 0.25 11.2 1.6 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) LURAP PF14854.1 KXX78369.1 - 0.17 11.5 2.3 0.26 10.9 1.6 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein TcdA_TcdB_pore PF12920.2 KXX78369.1 - 3.7 5.3 5.3 5 4.9 3.6 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain cEGF PF12662.2 KXX78369.1 - 6.4 6.5 7.4 13 5.5 0.1 3.2 3 0 0 3 3 3 0 Complement Clr-like EGF-like DSS1_SEM1 PF05160.8 KXX78371.1 - 5.5e-24 83.7 19.1 6.4e-24 83.5 13.0 1.3 1 1 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 KXX78371.1 - 1.8 8.2 13.8 2 8.0 9.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3808 PF10300.4 KXX78372.1 - 1.4e-124 416.2 0.0 1.7e-124 415.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 KXX78372.1 - 10 6.5 9.9 0.82 10.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PGK PF00162.14 KXX78373.1 - 4.2e-151 502.8 0.6 4.7e-151 502.7 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 KXX78373.1 - 0.011 15.8 3.9 0.76 10.0 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Mpv17_PMP22 PF04117.7 KXX78374.1 - 2.9e-24 84.4 0.2 1.8e-23 81.9 0.1 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF746 PF05344.6 KXX78374.1 - 0.064 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Abhydrolase_6 PF12697.2 KXX78376.1 - 5.8e-06 26.3 0.3 7e-06 26.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78376.1 - 0.00012 21.8 0.1 0.00022 20.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KXX78376.1 - 0.072 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Med3 PF11593.3 KXX78376.1 - 0.075 12.2 6.8 0.097 11.8 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S9 PF00326.16 KXX78376.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family FA_hydroxylase PF04116.8 KXX78378.1 - 3.4e-05 24.2 0.2 3.4e-05 24.2 0.1 2.7 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily FSH1 PF03959.8 KXX78379.1 - 2.1e-23 82.8 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX78379.1 - 4.4e-05 23.4 3.0 0.00083 19.2 0.3 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX78379.1 - 0.0016 17.8 0.4 0.21 10.9 0.3 2.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KXX78379.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_15 PF01793.11 KXX78381.1 - 3.1e-123 410.9 1.7 3.9e-123 410.6 1.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4518 PF15008.1 KXX78381.1 - 2.7 6.9 5.3 9.2 5.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) AA_permease_2 PF13520.1 KXX78384.1 - 1.6e-63 214.7 46.6 2.1e-63 214.3 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX78384.1 - 4.9e-19 68.0 42.8 6.6e-19 67.6 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KXX78385.1 - 7.4e-17 61.7 4.2 1.6e-16 60.6 3.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX78385.1 - 4.5e-10 39.4 2.1 8.6e-10 38.5 1.5 1.5 1 0 0 1 1 1 1 KR domain DUF3814 PF12769.2 KXX78385.1 - 0.13 12.4 1.4 3.2 7.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3814) GMC_oxred_N PF00732.14 KXX78386.1 - 1.9e-51 174.9 0.0 2.6e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX78386.1 - 6.7e-30 104.2 0.1 1.3e-29 103.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX78386.1 - 0.00011 21.2 0.4 0.00062 18.7 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX78386.1 - 0.00025 20.0 0.1 0.00074 18.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KXX78386.1 - 0.00027 20.9 0.2 0.00067 19.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX78386.1 - 0.00037 20.4 0.0 0.0015 18.4 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX78386.1 - 0.0023 18.0 0.0 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX78386.1 - 0.0059 15.7 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KXX78386.1 - 0.03 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KXX78386.1 - 0.042 12.9 0.1 0.079 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KXX78386.1 - 0.042 13.8 0.2 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 KXX78386.1 - 0.046 12.2 0.0 0.28 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KXX78386.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SpoV PF08183.6 KXX78386.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein family AA_permease PF00324.16 KXX78387.1 - 6.2e-121 404.0 43.1 7.3e-121 403.8 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX78387.1 - 2.3e-31 108.7 47.0 3.2e-31 108.3 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.1 KXX78388.1 - 8.1e-19 67.8 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78388.1 - 2.1e-16 60.1 0.0 3.1e-15 56.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78388.1 - 5.9e-14 52.5 0.0 1.8e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78388.1 - 6.5e-14 52.2 0.0 6.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78388.1 - 1.6e-13 50.5 0.0 9.4e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78388.1 - 4.1e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX78388.1 - 7.5e-05 21.9 0.1 0.086 11.9 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX78388.1 - 9.2e-05 21.8 0.0 0.0003 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX78388.1 - 0.00014 21.8 2.9 0.00039 20.4 0.2 2.4 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 KXX78388.1 - 0.0011 17.9 0.0 0.043 12.6 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase RrnaAD PF00398.15 KXX78388.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KXX78388.1 - 0.0034 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 KXX78388.1 - 0.0072 15.4 0.0 0.057 12.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KXX78388.1 - 0.0085 15.4 0.0 0.69 9.2 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.6 KXX78388.1 - 0.029 13.0 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.4 KXX78388.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF1996 PF09362.5 KXX78390.1 - 1.9e-88 296.0 0.2 2.5e-88 295.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_18 PF13512.1 KXX78391.1 - 0.048 13.6 1.0 0.13 12.2 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3129 PF11327.3 KXX78392.1 - 2.6e-66 222.9 7.8 4.2e-66 222.2 5.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) Glyco_hydro_16 PF00722.16 KXX78393.1 - 2.7e-16 59.4 0.2 7e-16 58.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KXX78393.1 - 2.1e-06 26.2 8.0 0.00088 17.5 0.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.4 KXX78393.1 - 0.009 15.5 0.0 0.016 14.7 0.0 1.4 1 1 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) CVNH PF08881.5 KXX78395.1 - 1.8e-37 127.7 0.0 3e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 KXX78395.1 - 1.5e-13 50.3 0.0 2.6e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 KXX78395.1 - 9.1e-06 25.2 24.0 9.1e-06 25.2 16.7 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF2076 PF09849.4 KXX78395.1 - 0.0011 19.0 7.7 0.0021 18.1 5.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF533 PF04391.7 KXX78395.1 - 0.018 14.4 1.8 0.018 14.4 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) MIP-T3 PF10243.4 KXX78395.1 - 0.067 11.6 21.1 0.09 11.2 14.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 KXX78395.1 - 0.17 9.5 4.5 0.2 9.3 3.1 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 KXX78395.1 - 0.17 11.7 4.1 0.23 11.3 2.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 KXX78395.1 - 0.92 8.8 13.1 1.3 8.2 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KXX78395.1 - 3.5 7.3 6.3 5.2 6.7 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 KXX78395.1 - 8 6.2 5.5 12 5.6 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HET PF06985.6 KXX78396.1 - 7.4e-29 100.6 0.0 1.3e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.24 KXX78398.1 - 9e-44 148.9 0.0 2e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX78398.1 - 4.5e-22 77.7 0.0 1.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KXX78398.1 - 3.6e-21 74.4 0.0 8.8e-21 73.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KXX78398.1 - 0.044 13.6 0.0 0.044 13.6 0.0 3.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Sad1_UNC PF07738.8 KXX78399.1 - 6.3e-09 35.7 0.0 0.00089 19.0 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal FoP_duplication PF13865.1 KXX78399.1 - 0.022 15.2 1.3 0.022 15.2 0.9 3.4 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF1390 PF07150.6 KXX78399.1 - 0.11 11.7 0.4 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) OmpH PF03938.9 KXX78399.1 - 4.4 7.2 19.5 5.6 6.8 5.4 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Epimerase PF01370.16 KXX78400.1 - 1.6e-45 155.4 0.0 2.3e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KXX78400.1 - 4.2e-25 87.4 0.0 7.6e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KXX78400.1 - 9.3e-16 57.3 0.0 2e-15 56.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KXX78400.1 - 3.7e-14 52.3 0.0 6.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KXX78400.1 - 2.7e-13 49.4 0.2 2.2e-11 43.1 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KXX78400.1 - 5.3e-11 42.7 0.0 8.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KXX78400.1 - 6.7e-09 35.0 0.0 8.1e-08 31.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KXX78400.1 - 1.5e-08 34.9 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KXX78400.1 - 2.5e-07 30.5 0.0 5.1e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 KXX78400.1 - 0.0028 18.2 0.0 0.82 10.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KXX78400.1 - 0.0045 16.4 0.2 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 KXX78400.1 - 0.0067 15.7 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 KXX78400.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 KXX78400.1 - 0.088 11.6 0.3 0.15 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N PF00107.21 KXX78401.1 - 5.8e-28 97.0 0.0 8.9e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX78401.1 - 8.3e-17 62.2 0.0 1.7e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX78401.1 - 1.1e-08 34.8 0.0 5.2e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Radical_SAM PF04055.16 KXX78402.1 - 3.7e-18 66.2 0.1 9.1e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KXX78402.1 - 3.7e-07 30.3 0.1 6.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KXX78402.1 - 3.6e-06 26.9 0.1 7.1e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF4046 PF13255.1 KXX78402.1 - 0.11 11.1 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) ADK PF00406.17 KXX78403.1 - 7.9e-18 64.7 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KXX78403.1 - 5.2e-07 30.0 0.0 1.2e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX78403.1 - 8.2e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX78403.1 - 0.00048 20.9 0.0 0.00072 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DIE2_ALG10 PF04922.7 KXX78404.1 - 2.2e-74 250.8 5.3 6.3e-74 249.2 3.7 1.8 1 1 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.4 KXX78404.1 - 8.1e-14 51.0 0.7 4.6e-08 32.6 0.1 2.9 2 0 0 2 2 2 2 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LSR PF05624.9 KXX78406.1 - 4.2 7.1 10.0 1.6 8.4 1.6 3.0 3 0 0 3 3 3 0 Lipolysis stimulated receptor (LSR) DUF2663 PF10864.3 KXX78406.1 - 6.6 6.9 6.0 44 4.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Chitin_bind_1 PF00187.14 KXX78408.1 - 6.3e-06 26.0 14.2 6.3e-06 26.0 9.9 2.8 2 1 0 2 2 2 1 Chitin recognition protein Conotoxin PF02950.12 KXX78408.1 - 2.9 8.7 8.8 0.92 10.3 0.1 2.3 1 1 1 2 2 2 0 Conotoxin Phytase PF02333.10 KXX78409.1 - 3e-54 184.2 0.0 1.6e-53 181.8 0.0 1.9 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 KXX78409.1 - 3e-05 24.0 36.0 0.022 14.9 8.0 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 KXX78409.1 - 0.029 14.3 24.7 0.34 10.9 3.9 2.4 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_11 PF00457.12 KXX78410.1 - 1.6e-70 236.1 16.5 1.9e-70 235.9 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Pyr_redox_3 PF13738.1 KXX78411.1 - 1.1e-17 64.8 0.0 3.9e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KXX78411.1 - 2.9e-14 52.1 0.0 3.4e-13 48.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KXX78411.1 - 7.1e-10 39.0 0.0 0.00051 19.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX78411.1 - 1.5e-07 31.3 1.1 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KXX78411.1 - 8.8e-07 28.1 0.1 2.8e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KXX78411.1 - 1.1e-06 27.7 0.5 3.2e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KXX78411.1 - 1.8e-05 24.8 0.3 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KXX78411.1 - 2.6e-05 24.5 2.8 0.022 15.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KXX78411.1 - 0.00067 19.3 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KXX78411.1 - 0.013 15.2 3.0 0.064 13.0 0.2 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KXX78411.1 - 0.033 13.2 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX78411.1 - 0.067 11.6 1.9 0.18 10.2 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KXX78411.1 - 0.085 11.6 3.6 0.06 12.1 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KXX78411.1 - 0.16 12.2 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KXX78411.1 - 0.48 9.9 4.4 8.2 5.9 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KXX78411.1 - 0.94 8.2 3.6 0.36 9.6 0.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A EMP70 PF02990.11 KXX78413.1 - 3.9e-197 655.8 5.4 5.1e-197 655.4 3.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 KXX78413.1 - 0.12 11.6 1.3 0.27 10.4 0.9 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 KXX78414.1 - 6.2e-16 58.3 3.2 1.1e-15 57.6 2.2 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Menin PF05053.8 KXX78414.1 - 0.087 10.9 2.7 0.11 10.5 1.8 1.2 1 0 0 1 1 1 0 Menin Transp_cyt_pur PF02133.10 KXX78415.1 - 1e-148 495.5 35.0 1.2e-148 495.3 24.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Med4 PF10018.4 KXX78416.1 - 2e-50 170.7 21.6 4e-50 169.8 14.7 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ARGLU PF15346.1 KXX78416.1 - 0.0031 17.3 17.2 0.0031 17.3 11.9 1.9 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 UDPG_MGDP_dh_C PF03720.10 KXX78416.1 - 0.041 14.0 0.7 0.089 12.9 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PAT1 PF09770.4 KXX78416.1 - 0.08 11.1 18.7 0.097 10.8 13.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KXX78416.1 - 0.16 11.8 11.7 0.23 11.3 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.26 KXX78417.1 - 3.3e-11 42.8 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Curlin_rpt PF07012.7 KXX78417.1 - 0.59 9.8 3.5 0.86 9.3 0.7 2.3 2 0 0 2 2 2 0 Curlin associated repeat NMD3 PF04981.8 KXX78418.1 - 0.0099 15.0 0.3 0.015 14.4 0.2 1.4 1 0 0 1 1 1 1 NMD3 family Rsa3 PF14615.1 KXX78418.1 - 0.021 14.1 0.0 0.061 12.6 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DUF2373 PF10180.4 KXX78418.1 - 0.033 13.7 0.1 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DZR PF12773.2 KXX78418.1 - 0.22 11.3 3.1 1.8 8.4 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KXX78418.1 - 0.32 10.5 1.7 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 DUF164 PF02591.10 KXX78418.1 - 0.39 10.5 2.2 1.1 9.1 0.4 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C3HC4_2 PF13923.1 KXX78418.1 - 1.1 9.3 3.7 2.2 8.4 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KXX78419.1 - 3.9e-55 184.1 24.6 2.2e-09 37.5 0.0 14.2 7 5 6 14 14 14 13 Ankyrin repeats (3 copies) Ank PF00023.25 KXX78419.1 - 1.1e-26 91.2 32.3 0.00023 20.8 0.0 18.9 19 2 1 20 20 20 10 Ankyrin repeat Ank_3 PF13606.1 KXX78419.1 - 2.8e-22 76.5 10.9 0.0036 17.3 0.0 17.9 20 1 1 21 21 21 4 Ankyrin repeat Ank_4 PF13637.1 KXX78419.1 - 3.1e-17 62.5 13.3 0.0019 18.6 0.0 14.2 15 2 1 16 16 16 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX78419.1 - 2.4e-13 49.8 19.1 0.00017 21.7 0.0 13.5 14 2 2 16 16 16 4 Ankyrin repeats (many copies) Aminotran_4 PF01063.14 KXX78420.1 - 0.064 12.7 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class IV Acid_PPase PF12689.2 KXX78420.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase Acetyltransf_9 PF13527.1 KXX78421.1 - 7.8e-05 22.5 0.0 0.00018 21.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX78421.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX78421.1 - 0.007 16.4 0.0 0.046 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX78421.1 - 0.058 13.4 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF2264 PF10022.4 KXX78422.1 - 6.1e-126 419.8 0.3 7.8e-126 419.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 KXX78422.1 - 0.23 11.9 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat FH2 PF02181.18 KXX78423.1 - 6.9e-80 268.6 5.8 6.9e-80 268.6 4.0 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KXX78423.1 - 2.8e-65 219.2 0.1 9.3e-65 217.5 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KXX78423.1 - 8.2e-55 185.2 5.5 1.6e-54 184.3 1.5 3.0 2 1 1 3 3 3 1 Diaphanous FH3 Domain Lysine_decarbox PF03641.9 KXX78425.1 - 1.9e-30 105.3 0.0 2.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Glt_symporter PF03616.9 KXX78425.1 - 0.043 12.3 2.6 1.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter Proteasome PF00227.21 KXX78426.1 - 3.3e-51 173.2 0.0 4.2e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX78426.1 - 3e-11 42.4 0.2 4.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1777 PF08648.7 KXX78427.1 - 1.6e-22 80.1 111.7 2.2e-21 76.4 46.9 3.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Elong_Iki1 PF10483.4 KXX78428.1 - 3.4e-60 203.8 0.0 3.8e-34 118.3 0.0 2.0 2 0 0 2 2 2 2 Elongator subunit Iki1 RAMP4 PF06624.7 KXX78429.1 - 1.3e-06 27.8 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.1 KXX78430.1 - 1e-18 67.3 3.7 1e-18 67.3 2.5 5.1 3 1 0 3 3 3 1 Small acidic protein family AIF-MLS PF14962.1 KXX78431.1 - 0.23 11.0 3.2 0.47 10.0 2.2 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF1168 PF06658.7 KXX78431.1 - 0.39 10.2 7.9 0.85 9.1 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CLPTM1 PF05602.7 KXX78432.1 - 3.6e-161 536.7 0.0 4.5e-161 536.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) ASXH PF13919.1 KXX78433.1 - 7.8e-20 71.0 0.1 1.4e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 KXX78434.1 - 9e-26 89.2 0.1 1.6e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KXX78434.1 - 1.1e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 KXX78434.1 - 0.017 14.9 0.8 0.017 14.9 0.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seadorna_VP6 PF07407.6 KXX78434.1 - 0.064 12.0 0.7 0.23 10.1 0.2 1.8 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF334 PF03904.8 KXX78434.1 - 0.082 12.2 2.1 6.9 5.9 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF4404 PF14357.1 KXX78434.1 - 0.091 13.1 1.4 11 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Sensor PF13796.1 KXX78435.1 - 0.0048 16.5 1.8 0.0062 16.1 1.2 1.1 1 0 0 1 1 1 1 Putative sensor Metallophos PF00149.23 KXX78436.1 - 5e-38 130.5 0.1 7.3e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KXX78436.1 - 1.6e-31 108.1 0.5 4e-31 106.8 0.1 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 KXX78436.1 - 4.7e-25 87.0 4.6 1.2e-17 63.3 0.9 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KXX78436.1 - 3.9e-19 67.3 1.8 1.3e-05 24.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78436.1 - 1.2e-15 56.0 0.9 0.0007 19.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX78436.1 - 2e-06 27.5 3.8 0.0028 17.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78436.1 - 2.2e-06 28.1 0.0 0.013 16.1 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX78436.1 - 8.9e-05 22.7 0.0 0.29 11.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX78436.1 - 0.00032 20.9 0.0 4.6 7.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KXX78436.1 - 0.00054 19.1 0.1 0.055 12.5 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KXX78436.1 - 0.00095 18.9 0.0 0.067 13.0 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX78436.1 - 0.0011 19.0 0.3 0.0023 17.9 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KXX78436.1 - 0.0037 17.1 0.4 1 9.3 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX78436.1 - 0.014 15.0 0.7 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_N_3 PF13417.1 KXX78438.1 - 1.4e-12 47.5 0.0 4e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX78438.1 - 1.6e-12 47.2 0.0 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KXX78438.1 - 5e-12 45.8 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX78438.1 - 3.9e-11 42.6 0.0 7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX78438.1 - 1.2e-10 41.2 0.0 4.2e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX78438.1 - 6.6e-09 36.1 0.1 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KXX78438.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.8 1 1 0 1 1 1 0 MetRS-N binding domain NmrA PF05368.8 KXX78439.1 - 9.3e-12 44.6 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX78439.1 - 0.00022 21.3 0.1 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX78439.1 - 0.0021 16.7 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KXX78439.1 - 0.0032 16.1 0.1 0.0056 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioesterase PF00975.15 KXX78440.1 - 2.9e-19 70.2 0.2 8.9e-19 68.6 0.2 1.9 1 1 0 1 1 1 1 Thioesterase domain AMP-binding PF00501.23 KXX78440.1 - 7.5e-13 47.6 0.9 3.1e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme DLH PF01738.13 KXX78440.1 - 0.062 12.5 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family TB2_DP1_HVA22 PF03134.14 KXX78441.1 - 2.5e-32 110.4 5.6 3.4e-32 110.0 3.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.16 KXX78441.1 - 5.5 5.8 10.4 22 3.8 7.2 1.8 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.10 KXX78442.1 - 7.7e-30 102.8 0.1 1.8e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.3 KXX78443.1 - 1e-18 66.9 0.1 3.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KXX78443.1 - 5.1e-17 62.5 1.1 6.2e-17 62.2 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78443.1 - 3.1e-15 56.2 0.1 4.3e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX78443.1 - 1.5e-05 24.7 0.1 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KXX78443.1 - 0.0049 16.4 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KXX78443.1 - 0.031 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KXX78443.1 - 0.056 13.0 0.2 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Cation_efflux PF01545.16 KXX78444.1 - 1.1e-08 34.4 3.2 1.4e-08 34.1 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family Marek_A PF02124.10 KXX78446.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.4 1 1 0 1 1 1 0 Marek's disease glycoprotein A 7TM_GPCR_Srsx PF10320.4 KXX78446.1 - 0.21 10.6 0.9 0.26 10.3 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Chorismate_bind PF00425.13 KXX78447.1 - 7.6e-63 212.2 0.2 6.4e-35 120.7 0.0 3.2 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KXX78447.1 - 1.1e-21 77.1 0.0 8.1e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KXX78447.1 - 2.1e-12 47.2 0.0 4.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KXX78447.1 - 5.1e-05 22.8 0.6 0.019 14.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 Vps55 PF04133.9 KXX78448.1 - 1.7e-45 153.5 8.6 1.9e-45 153.4 6.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Gram_pos_anchor PF00746.16 KXX78448.1 - 4.5 7.2 8.4 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Gram positive anchor adh_short_C2 PF13561.1 KXX78449.1 - 6.1e-08 32.7 0.0 9.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX78449.1 - 1.2e-07 31.8 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF904 PF06005.7 KXX78449.1 - 0.023 14.9 0.1 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TRAPPC9-Trs120 PF08626.6 KXX78450.1 - 8.4e-142 473.8 0.0 9.7e-116 387.5 0.0 2.6 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TfuA PF07812.7 KXX78451.1 - 8.4e-16 57.4 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 TfuA-like protein HET PF06985.6 KXX78452.1 - 1.2e-21 77.2 0.0 2.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KXX78453.1 - 2e-12 46.5 24.8 9.1e-07 27.8 3.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX78453.1 - 0.00014 20.2 1.1 0.0002 19.7 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX78453.1 - 0.0039 15.8 4.5 0.0039 15.8 3.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter GST_N PF02798.15 KXX78454.1 - 7.7e-11 42.0 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX78454.1 - 1.2e-08 34.8 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX78454.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX78454.1 - 3.7e-08 33.4 0.0 7.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX78454.1 - 2e-07 30.7 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX78454.1 - 2.1e-07 31.3 0.1 3.3e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mid1 PF12929.2 KXX78456.1 - 1.1e-131 439.4 0.2 1.3e-131 439.2 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KXX78456.1 - 0.047 14.0 2.0 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Fz domain Fungal_trans_2 PF11951.3 KXX78457.1 - 3.8e-47 160.7 0.1 5e-28 97.7 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78457.1 - 7.5e-07 28.9 6.6 1.6e-06 27.9 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2638 PF10937.3 KXX78457.1 - 0.027 15.4 7.5 0.033 15.2 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2638) Ribosomal_S13 PF00416.17 KXX78458.1 - 1.8e-20 73.3 0.1 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.16 KXX78459.1 - 2.2e-98 329.1 0.0 2.6e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) bZIP_2 PF07716.10 KXX78460.1 - 1.5e-07 31.1 15.3 3.6e-07 29.9 10.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KXX78460.1 - 0.0021 17.9 14.0 0.0041 17.0 9.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KXX78460.1 - 0.26 11.5 13.9 0.089 13.0 7.6 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Snf7 PF03357.16 KXX78461.1 - 2.7e-05 23.6 24.6 2.7e-05 23.6 17.0 1.5 1 1 0 1 1 1 1 Snf7 LCD1 PF09798.4 KXX78461.1 - 0.33 8.8 10.8 0.39 8.6 7.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein XLF PF09302.6 KXX78461.1 - 0.87 9.3 5.4 0.39 10.4 0.3 2.6 1 1 1 2 2 2 0 XLF (XRCC4-like factor) Bud13 PF09736.4 KXX78461.1 - 0.96 9.7 18.6 2.7 8.2 0.8 2.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex Tyrosinase PF00264.15 KXX78461.1 - 4 7.5 5.8 13 5.8 4.0 1.7 1 1 0 1 1 1 0 Common central domain of tyrosinase GST_N_3 PF13417.1 KXX78462.1 - 2.4e-19 69.3 0.1 6.9e-19 67.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX78462.1 - 1.5e-14 53.7 0.0 3.1e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KXX78462.1 - 1.2e-11 44.5 0.0 2.8e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KXX78462.1 - 4.4e-05 23.3 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 KXX78462.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX78462.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX78462.1 - 0.065 13.7 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MMR_HSR1 PF01926.18 KXX78463.1 - 9.4e-09 35.2 0.0 2.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX78463.1 - 2.1e-05 23.7 0.0 5.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KXX78463.1 - 2.5e-05 23.7 0.0 7.8e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KXX78463.1 - 0.00067 19.1 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Septin PF00735.13 KXX78463.1 - 0.00067 18.7 0.1 0.0051 15.8 0.0 2.5 2 1 0 2 2 2 1 Septin MobB PF03205.9 KXX78463.1 - 0.013 15.2 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KXX78463.1 - 0.015 15.5 0.2 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 KXX78463.1 - 0.017 14.0 0.0 0.044 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.18 KXX78463.1 - 0.021 13.6 0.0 0.61 8.8 0.0 2.4 2 0 0 2 2 2 0 MCM2/3/5 family AAA_16 PF13191.1 KXX78463.1 - 0.024 14.6 0.0 0.093 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.11 KXX78463.1 - 0.025 13.6 0.7 2.1 7.4 0.1 2.7 3 0 0 3 3 3 0 AIG1 family AAA_23 PF13476.1 KXX78463.1 - 0.026 14.8 3.7 0.051 13.9 1.2 2.5 2 1 0 2 2 2 0 AAA domain IIGP PF05049.8 KXX78463.1 - 0.026 13.3 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KXX78463.1 - 0.028 14.2 1.3 4.8 6.9 0.1 3.0 3 0 0 3 3 2 0 Dynamin family AAA_10 PF12846.2 KXX78463.1 - 0.048 13.0 0.0 0.14 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 KXX78463.1 - 0.051 13.3 1.2 0.43 10.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 KXX78463.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 KXX78463.1 - 0.054 13.6 0.0 0.32 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KXX78463.1 - 0.07 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 KXX78463.1 - 0.12 12.5 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Pex16 PF08610.5 KXX78464.1 - 3.3e-104 348.4 0.1 3.9e-104 348.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SET PF00856.23 KXX78465.1 - 1.6e-12 48.0 0.0 1e-11 45.3 0.0 2.0 1 1 0 1 1 1 1 SET domain Nop16 PF09420.5 KXX78466.1 - 6.9e-52 175.8 12.0 1.3e-51 175.0 8.3 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.26 KXX78466.1 - 0.042 13.9 0.6 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX78466.1 - 0.057 13.5 0.6 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain FCH PF00611.18 KXX78467.1 - 4.9e-16 58.6 0.2 1.5e-14 53.9 0.0 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 KXX78467.1 - 9.2e-15 54.5 0.1 2.1e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 KXX78467.1 - 1.2e-11 44.1 0.0 2.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MARVEL PF01284.18 KXX78468.1 - 3.9e-06 26.7 13.0 6.2e-06 26.0 9.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 KXX78468.1 - 0.024 14.7 1.9 0.024 14.7 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) PMT PF02366.13 KXX78468.1 - 8.5 5.6 12.9 15 4.8 7.2 1.9 1 1 1 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase GMC_oxred_N PF00732.14 KXX78469.1 - 2.8e-76 256.5 0.0 3.7e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX78469.1 - 2.8e-36 124.9 0.0 5.3e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX78469.1 - 1.2e-05 24.4 0.2 0.0076 15.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX78469.1 - 0.0013 17.7 0.1 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KXX78469.1 - 0.0049 15.7 0.1 0.79 8.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KXX78469.1 - 0.017 14.2 0.1 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KXX78469.1 - 0.044 13.6 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_32 PF13679.1 KXX78470.1 - 1.8e-19 69.8 0.1 2.6e-18 66.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain zf-CHC2 PF01807.15 KXX78470.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CHC2 zinc finger DUF2379 PF09543.5 KXX78470.1 - 0.21 11.5 3.5 0.5 10.3 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Fructosamin_kin PF03881.9 KXX78471.1 - 1.2e-40 139.3 0.0 1.5e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KXX78471.1 - 4.7e-09 36.3 0.0 7.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family AIG2 PF06094.7 KXX78472.1 - 4.9e-17 62.2 0.2 7.4e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 AIG2-like family Chitin_bind_3 PF03067.10 KXX78473.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 2 0 0 2 2 2 1 Chitin binding domain FAT PF02259.18 KXX78474.1 - 1.1e-76 258.0 4.8 4.3e-76 256.1 3.6 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KXX78474.1 - 8e-23 81.1 0.1 3.8e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TPR_17 PF13431.1 KXX78474.1 - 0.0028 17.7 0.0 34 4.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Urb2 PF10441.4 KXX78474.1 - 0.0074 15.9 0.9 0.61 9.6 0.1 3.3 3 0 0 3 3 3 1 Urb2/Npa2 family DSHCT PF08148.7 KXX78475.1 - 2.6e-61 205.9 0.4 5.1e-61 205.0 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KXX78475.1 - 5.8e-21 74.7 0.0 1.6e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX78475.1 - 4e-06 26.5 1.1 1.3e-05 24.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KXX78475.1 - 0.043 12.9 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain Cut8_C PF08559.5 KXX78475.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Cut8 six-helix bundle dCMP_cyt_deam_1 PF00383.17 KXX78476.1 - 6.3e-13 48.2 0.0 1.1e-12 47.5 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KXX78476.1 - 0.017 14.7 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain WD40 PF00400.27 KXX78477.1 - 7.1e-06 25.7 0.1 2.5 8.1 0.0 5.8 5 1 0 5 5 5 1 WD domain, G-beta repeat PGAP1 PF07819.8 KXX78477.1 - 1.9e-05 24.3 0.2 3.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KXX78477.1 - 0.00051 19.9 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78477.1 - 0.0024 17.6 0.0 0.0086 15.8 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 KXX78477.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KXX78477.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ACT_7 PF13840.1 KXX78478.1 - 3e-19 68.3 0.1 6e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain DHHA1 PF02272.14 KXX78478.1 - 0.65 9.7 5.3 1.5 8.5 3.7 1.6 1 0 0 1 1 1 0 DHHA1 domain UPF0029 PF01205.14 KXX78479.1 - 8.3e-31 105.9 0.0 1.7e-30 104.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KXX78479.1 - 2.2e-10 40.4 0.0 3.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain RabGAP-TBC PF00566.13 KXX78480.1 - 1.5e-33 116.0 0.3 3.1e-31 108.5 0.1 2.9 2 1 0 2 2 2 2 Rab-GTPase-TBC domain UQ_con PF00179.21 KXX78481.1 - 9.9e-41 138.4 0.0 1.2e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX78481.1 - 0.00059 19.5 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX78481.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KXX78481.1 - 0.033 13.8 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain TPR_11 PF13414.1 KXX78483.1 - 0.0011 18.5 2.9 8.1 6.1 0.1 5.1 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.1 KXX78483.1 - 0.01 15.9 0.5 10 6.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1786 PF08735.5 KXX78483.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) TPR_1 PF00515.23 KXX78483.1 - 0.12 12.0 2.1 21 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX78483.1 - 0.12 12.7 2.9 16 5.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78483.1 - 0.51 11.0 16.6 7.3 7.3 1.6 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX78483.1 - 0.58 10.9 14.9 5.2 7.9 0.5 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Fasciclin PF02469.17 KXX78484.1 - 1.4e-42 144.6 0.0 2.8e-25 88.7 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain DUF4611 PF15387.1 KXX78484.1 - 2.2 8.4 11.5 15 5.8 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) TPR_19 PF14559.1 KXX78486.1 - 3.4e-05 24.1 1.5 0.084 13.2 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX78486.1 - 0.017 15.2 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KXX78486.1 - 0.018 14.9 5.5 1.3 9.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX78486.1 - 0.07 12.7 0.8 10 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX78486.1 - 0.14 12.0 0.6 12 6.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX78486.1 - 0.73 10.4 6.0 60 4.4 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 KXX78487.1 - 1.2e-18 67.7 0.3 1.1e-17 64.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KXX78487.1 - 8.3e-12 44.5 9.2 2.5e-11 43.0 6.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3446 PF11928.3 KXX78487.1 - 0.52 10.5 5.5 0.28 11.4 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) BSP_II PF05432.6 KXX78487.1 - 5.5 6.1 5.6 9.8 5.3 3.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Methyltransf_23 PF13489.1 KXX78489.1 - 6.1e-18 65.0 0.0 2.2e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78489.1 - 2.2e-10 41.1 0.1 2.6e-09 37.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78489.1 - 4.1e-09 36.1 0.0 4.5e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78489.1 - 6e-07 29.8 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78489.1 - 2.7e-06 27.7 0.0 2.1e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78489.1 - 0.0015 18.8 0.0 0.0041 17.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX78489.1 - 0.019 14.0 0.0 0.066 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 KXX78489.1 - 0.048 13.7 0.0 0.96 9.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KXX78489.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KXX78489.1 - 0.097 11.7 0.0 14 4.7 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pal1 PF08316.6 KXX78490.1 - 2.4e-47 160.9 0.2 7.6e-47 159.2 0.1 1.9 1 0 0 1 1 1 1 Pal1 cell morphology protein CorA PF01544.13 KXX78491.1 - 3.6e-06 26.2 0.7 5.8e-06 25.5 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PIG-Y PF15159.1 KXX78491.1 - 0.016 15.4 1.1 0.036 14.2 0.7 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pkinase PF00069.20 KXX78492.1 - 1.8e-38 132.2 0.0 2.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78492.1 - 1.1e-13 50.8 0.0 1.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX78492.1 - 1.7e-05 24.7 0.0 0.0015 18.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KXX78492.1 - 0.057 12.1 0.1 0.089 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Exo_endo_phos PF03372.18 KXX78493.1 - 2.8e-12 47.1 9.6 1.5e-11 44.6 6.7 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family POP1 PF06978.6 KXX78494.1 - 2.9e-66 222.6 14.9 2.9e-66 222.6 10.3 3.5 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KXX78494.1 - 1.3e-29 101.8 0.0 4.8e-29 100.0 0.0 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain IBR PF01485.16 KXX78494.1 - 4.2e-12 45.7 25.2 2.3e-06 27.3 4.4 3.8 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KXX78494.1 - 0.00043 20.0 8.7 0.00043 20.0 6.1 3.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 KXX78494.1 - 0.0016 18.1 5.2 0.0048 16.5 3.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger HSP70 PF00012.15 KXX78495.1 - 1e-77 261.4 2.5 1e-77 261.4 1.7 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX78495.1 - 1.2e-06 27.4 0.2 2.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KXX78495.1 - 0.0034 16.5 0.5 0.014 14.5 0.2 2.0 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Peptidase_M17_N PF02789.12 KXX78495.1 - 0.024 14.3 2.0 0.064 13.0 0.4 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain TFIIF_alpha PF05793.7 KXX78495.1 - 0.05 11.9 7.8 0.082 11.2 5.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 KXX78495.1 - 0.065 12.7 4.4 0.13 11.7 3.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KXX78495.1 - 0.58 10.4 7.8 1.4 9.2 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tom22 PF04281.8 KXX78495.1 - 0.76 9.2 6.4 1.9 7.9 4.4 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Daxx PF03344.10 KXX78495.1 - 1 7.7 7.6 1.7 6.9 5.3 1.3 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 KXX78495.1 - 1.4 8.9 6.2 3.3 7.7 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 KXX78495.1 - 4.7 6.7 13.5 0.79 9.3 4.6 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region NT-C2 PF10358.4 KXX78496.1 - 4.9e-18 64.9 0.0 1.5e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C2H2 PF00096.21 KXX78497.1 - 2.4e-06 27.5 24.6 0.0042 17.3 1.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX78497.1 - 8.8e-05 22.5 24.9 0.026 14.8 1.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger Adeno_E3_CR2 PF02439.10 KXX78497.1 - 0.0049 16.3 0.8 0.0087 15.5 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Sina PF03145.11 KXX78497.1 - 0.6 9.7 14.2 2.3 7.8 6.1 2.2 1 1 1 2 2 2 0 Seven in absentia protein family zf-met2 PF12907.2 KXX78497.1 - 2.1 8.4 12.6 6.5 6.8 0.3 3.9 4 0 0 4 4 4 0 Zinc-binding ATP_bind_1 PF03029.12 KXX78499.1 - 2.4e-76 256.4 0.0 3.8e-76 255.7 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KXX78499.1 - 8.5e-06 25.3 2.7 0.00014 21.3 0.1 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KXX78499.1 - 8.8e-06 24.6 0.0 0.013 14.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 KXX78499.1 - 0.00029 20.3 1.4 0.0016 17.9 1.0 2.0 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 KXX78499.1 - 0.00036 21.0 0.1 0.62 10.5 0.0 3.0 3 1 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 KXX78499.1 - 0.00043 20.4 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KXX78499.1 - 0.00065 19.6 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KXX78499.1 - 0.0013 18.6 1.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KXX78499.1 - 0.0027 17.3 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KXX78499.1 - 0.0034 18.2 0.7 0.027 15.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 KXX78499.1 - 0.0062 15.8 0.0 0.14 11.4 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B G-alpha PF00503.15 KXX78499.1 - 0.0073 15.0 1.0 0.51 8.9 0.0 3.0 3 0 0 3 3 3 1 G-protein alpha subunit AAA_16 PF13191.1 KXX78499.1 - 0.0085 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 KXX78499.1 - 0.0098 15.3 0.0 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 KXX78499.1 - 0.011 14.6 0.7 0.016 14.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Arf PF00025.16 KXX78499.1 - 0.015 14.5 0.0 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family PRK PF00485.13 KXX78499.1 - 0.018 14.5 0.1 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 KXX78499.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KXX78499.1 - 0.021 14.5 0.1 0.097 12.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KXX78499.1 - 0.023 14.1 0.0 0.56 9.6 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain U1snRNP70_N PF12220.3 KXX78499.1 - 0.03 14.6 2.4 0.068 13.5 1.6 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_23 PF13476.1 KXX78499.1 - 0.038 14.3 0.1 5.5 7.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KXX78499.1 - 0.058 12.8 0.1 0.89 9.0 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KXX78499.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 KXX78499.1 - 0.073 12.4 0.5 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase DUF87 PF01935.12 KXX78499.1 - 0.081 12.7 0.3 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 KXX78499.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KXX78499.1 - 0.65 10.3 7.6 0.7 10.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain CDC27 PF09507.5 KXX78499.1 - 3 6.9 12.1 4.4 6.4 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CwfJ_C_1 PF04677.10 KXX78501.1 - 2.7e-24 85.1 0.0 1.5e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KXX78501.1 - 1.3e-23 83.2 0.1 1.3e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 MIP-T3 PF10243.4 KXX78501.1 - 0.11 10.9 33.2 0.17 10.2 23.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DEAD PF00270.24 KXX78502.1 - 4.4e-44 149.9 0.0 8.9e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX78502.1 - 4e-26 90.6 0.0 6.9e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX78502.1 - 7.2e-05 22.6 0.0 0.0003 20.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX78502.1 - 0.065 13.3 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KXX78502.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.1 KXX78502.1 - 0.074 12.8 1.6 0.13 12.0 0.1 2.1 2 1 0 2 2 2 0 Part of AAA domain ChAPs PF09295.5 KXX78503.1 - 4.7e-160 532.6 0.0 5.9e-160 532.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 KXX78503.1 - 3.3e-06 27.2 4.2 0.84 10.4 0.3 5.2 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX78503.1 - 1.9e-05 24.2 1.1 0.12 12.0 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KXX78503.1 - 4.8e-05 22.9 0.5 0.041 13.8 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KXX78503.1 - 0.0002 21.1 0.2 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX78503.1 - 0.00029 21.1 0.1 0.5 10.7 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX78503.1 - 0.0011 18.5 0.1 1.8 8.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX78503.1 - 0.0021 17.7 0.6 1.3 8.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX78503.1 - 0.0032 17.0 0.1 1.4 8.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX78503.1 - 0.02 15.3 0.3 19 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX78503.1 - 0.021 14.7 0.1 6.4 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KXX78503.1 - 0.03 14.4 1.9 14 5.9 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KXX78503.1 - 0.11 13.2 1.4 6.9 7.4 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KXX78504.1 - 1.1e-51 175.4 0.0 1.3e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.18 KXX78505.1 - 9e-18 64.6 0.0 1.6e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KXX78505.1 - 7.1e-09 35.9 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KXX78505.1 - 0.00028 20.5 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Strep_his_triad PF04270.8 KXX78505.1 - 0.038 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Streptococcal histidine triad protein DNA_RNApol_7kD PF03604.8 KXX78506.1 - 1e-15 56.8 2.4 1.3e-15 56.5 1.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 KXX78506.1 - 0.0032 17.3 0.1 0.95 9.4 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 KXX78506.1 - 0.0033 17.2 0.4 0.0047 16.7 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 KXX78506.1 - 0.018 14.7 0.3 0.022 14.4 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 KXX78506.1 - 0.024 14.5 1.0 0.54 10.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn-ribbon_8 PF09723.5 KXX78506.1 - 0.08 12.9 0.5 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain RRN7 PF11781.3 KXX78506.1 - 0.21 11.1 3.0 0.38 10.2 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Brix PF04427.13 KXX78507.1 - 9.2e-58 195.0 0.0 1.2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF2681 PF10883.3 KXX78507.1 - 5.8 7.1 9.1 13 6.0 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_S49_N PF08496.5 KXX78507.1 - 6.1 6.6 9.1 14 5.4 6.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3366 PF11846.3 KXX78508.1 - 0.026 14.3 0.1 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) PepSY_TM_2 PF13703.1 KXX78509.1 - 0.37 10.9 6.8 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Methyltransf_23 PF13489.1 KXX78511.1 - 3.8e-21 75.4 0.0 5.5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78511.1 - 9.8e-13 47.9 0.0 3.7e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78511.1 - 3.5e-12 46.9 0.0 5.9e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78511.1 - 8.1e-08 32.6 0.0 2e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78511.1 - 3.9e-05 24.0 0.0 0.00046 20.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78511.1 - 0.00035 20.8 0.0 0.00082 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX78511.1 - 0.00089 18.3 0.0 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KXX78511.1 - 0.0018 18.2 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX78511.1 - 0.0036 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KXX78511.1 - 0.0049 16.2 0.0 0.013 14.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KXX78511.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KXX78511.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KXX78511.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Abhydrolase_5 PF12695.2 KXX78512.1 - 0.00017 21.3 0.0 0.00049 19.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF87 PF01935.12 KXX78512.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 FOLN PF09289.5 KXX78514.1 - 0.00087 19.0 4.5 0.037 13.8 0.3 5.3 7 0 0 7 7 7 3 Follistatin/Osteonectin-like EGF domain Pirin_C PF05726.8 KXX78514.1 - 0.0021 18.0 0.0 7.4 6.6 0.0 3.1 3 0 0 3 3 3 3 Pirin C-terminal cupin domain HET PF06985.6 KXX78515.1 - 3.9e-19 69.1 0.0 6.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KXX78516.1 - 6.3e-20 71.1 55.0 1.6e-13 50.0 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhC PF14143.1 KXX78516.1 - 3 7.8 11.2 3.7 7.5 1.9 3.5 3 0 0 3 3 3 0 YrhC-like protein DUF1304 PF06993.7 KXX78516.1 - 5.1 6.8 10.6 0.94 9.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Cyclin_N PF00134.18 KXX78517.1 - 2e-13 50.0 0.0 3.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KXX78517.1 - 2.2e-10 41.1 0.3 4.6e-10 40.1 0.2 1.5 1 1 0 1 1 1 1 Cyclin GST_C_3 PF14497.1 KXX78518.1 - 6.2e-11 42.6 0.0 9.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX78518.1 - 0.00036 20.3 0.1 0.00079 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX78518.1 - 0.082 13.1 0.1 0.49 10.6 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p450 PF00067.17 KXX78520.1 - 3.5e-51 174.1 0.0 4.8e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KXX78521.1 - 7e-73 244.9 0.0 8.6e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78521.1 - 1.3e-31 109.5 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX78521.1 - 0.0016 17.4 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX78521.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KXX78521.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KXX78521.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.1 KXX78522.1 - 6e-32 111.0 0.0 9.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KXX78522.1 - 0.0022 18.4 0.0 0.068 13.6 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1996 PF09362.5 KXX78524.1 - 6.2e-61 206.0 0.1 8.2e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.2 KXX78525.1 - 1e-29 102.7 5.0 7.6e-18 64.6 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX78525.1 - 1.6e-27 95.3 1.1 2.3e-09 37.5 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KXX78525.1 - 1.5e-25 87.6 6.7 4.9e-06 26.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KXX78525.1 - 6.9e-22 76.9 12.4 7.1e-08 32.4 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78525.1 - 8.2e-21 72.0 2.0 0.00037 20.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat DUF835 PF05763.7 KXX78525.1 - 0.00073 19.0 0.1 4.9 6.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF835) Inh PF02974.9 KXX78525.1 - 0.003 17.0 0.0 0.99 9.0 0.0 2.2 1 1 1 2 2 2 2 Protease inhibitor Inh APCDDC PF14921.1 KXX78525.1 - 0.053 12.8 0.0 2.1 7.6 0.0 2.1 1 1 1 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 DUF3425 PF11905.3 KXX78525.1 - 0.13 12.1 0.1 13 5.6 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3425) WD40 PF00400.27 KXX78527.1 - 8.1e-33 111.1 10.3 2.9e-16 58.6 0.4 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.7 KXX78527.1 - 4.5e-11 42.6 0.1 1.6e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX78527.1 - 9e-08 32.3 0.8 3.4e-07 30.4 0.1 2.3 3 0 0 3 3 3 1 AAA ATPase domain Nup160 PF11715.3 KXX78527.1 - 7.3e-05 21.0 2.0 0.096 10.7 0.2 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 KAP_NTPase PF07693.9 KXX78527.1 - 0.011 14.8 0.7 0.026 13.5 0.5 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 KXX78527.1 - 0.011 15.4 0.0 0.04 13.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KXX78527.1 - 0.011 15.8 0.0 0.037 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KXX78527.1 - 0.074 11.9 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sugar_tr PF00083.19 KXX78528.1 - 9.2e-106 354.1 27.5 1.1e-105 353.8 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX78528.1 - 6.6e-17 61.2 30.7 6.6e-17 61.2 21.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Trehalase PF01204.13 KXX78528.1 - 0.049 12.2 2.3 0.51 8.9 0.0 2.7 3 0 0 3 3 3 0 Trehalase MIF4G PF02854.14 KXX78530.1 - 9.6e-22 77.4 0.0 1.7e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KXX78530.1 - 8.6e-16 57.6 0.2 1e-14 54.2 0.0 2.9 3 1 0 3 3 3 1 MA3 domain SKG6 PF08693.5 KXX78531.1 - 2.7e-06 26.5 0.0 6.6e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KXX78531.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Sporozoite_P67 PF05642.6 KXX78531.1 - 0.25 9.1 9.5 0.27 9.0 6.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_UL32 PF06070.6 KXX78531.1 - 0.49 8.7 5.8 0.67 8.3 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Glyco_hydro_47 PF01532.15 KXX78532.1 - 1.7e-157 524.6 0.0 2e-157 524.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pyr_redox_dim PF02852.17 KXX78533.1 - 3.1e-39 133.4 0.3 1.1e-38 131.5 0.0 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KXX78533.1 - 5.8e-33 114.4 20.2 1.3e-31 110.0 13.7 4.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX78533.1 - 9.6e-26 90.0 12.2 1.4e-21 76.6 1.6 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX78533.1 - 5e-12 45.6 3.7 2.3e-06 27.5 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX78533.1 - 6.5e-11 41.7 7.8 5.3e-07 28.8 1.7 3.3 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 KXX78533.1 - 8.1e-11 41.6 4.7 1.3e-09 37.7 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 KXX78533.1 - 8.2e-11 41.3 9.9 5.9e-09 35.2 1.8 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KXX78533.1 - 3.6e-10 39.2 17.8 9.6e-05 21.4 1.5 4.2 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX78533.1 - 2.2e-07 31.1 3.5 0.025 14.6 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX78533.1 - 5.8e-07 28.8 2.5 7.8e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KXX78533.1 - 2.9e-06 26.0 14.8 7.4e-05 21.3 1.2 3.8 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KXX78533.1 - 1e-05 25.1 2.5 0.032 13.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KXX78533.1 - 0.00023 20.3 9.7 0.076 12.0 0.9 3.3 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 KXX78533.1 - 0.0014 18.8 2.4 1.4 9.1 0.3 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX78533.1 - 0.0032 16.4 4.0 0.04 12.8 0.4 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 KXX78533.1 - 0.012 14.5 1.7 1 8.2 0.0 3.2 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KXX78533.1 - 0.013 14.6 1.0 3.9 6.5 0.1 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KXX78533.1 - 0.066 11.8 6.4 0.05 12.2 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KXX78533.1 - 0.53 9.9 9.4 0.12 12.0 0.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KXX78533.1 - 0.8 9.0 4.9 3.2 7.1 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NUDIX_2 PF13869.1 KXX78534.1 - 2.1e-47 160.9 0.0 1.3e-31 109.3 0.0 2.0 1 1 1 2 2 2 2 Nucleotide hydrolase DUF4316 PF14195.1 KXX78534.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF4177 PF13783.1 KXX78534.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) UPF0047 PF01894.12 KXX78535.1 - 1.7e-39 134.2 0.0 2.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 SMC_N PF02463.14 KXX78536.1 - 8e-25 87.3 0.0 4.2e-24 84.9 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KXX78536.1 - 1.3e-06 28.9 44.4 1.3e-06 28.9 30.8 5.6 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KXX78536.1 - 1.3e-06 28.6 0.9 0.00014 21.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KXX78536.1 - 0.00018 21.3 0.0 0.00063 19.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KXX78536.1 - 0.00075 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KXX78536.1 - 0.0011 17.5 3.2 0.0011 17.5 2.3 5.8 2 2 4 6 6 6 2 AAA domain AAA_15 PF13175.1 KXX78536.1 - 0.54 9.2 19.0 0.072 12.1 9.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain COQ9 PF08511.6 KXX78537.1 - 3.4e-27 93.7 0.0 9.6e-27 92.3 0.0 1.7 2 0 0 2 2 2 1 COQ9 DUF3422 PF11902.3 KXX78537.1 - 0.056 12.3 0.1 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) RRM_1 PF00076.17 KXX78538.1 - 1.3e-49 165.6 0.0 1.9e-18 65.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX78538.1 - 2.3e-39 133.2 0.0 1.5e-14 53.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX78538.1 - 2e-21 75.6 0.0 2.1e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX78538.1 - 5e-05 23.0 0.0 0.75 9.6 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KXX78538.1 - 9.3e-05 22.1 0.2 5.2 6.8 0.0 4.0 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 KXX78538.1 - 0.0015 17.9 0.0 0.033 13.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain PknH_C PF14032.1 KXX78538.1 - 0.033 13.7 0.1 33 3.9 0.0 3.3 3 0 0 3 3 3 0 PknH-like extracellular domain SRP14 PF02290.10 KXX78539.1 - 1.8e-25 88.6 0.0 2.7e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Hexokinase_2 PF03727.11 KXX78539.1 - 0.091 11.9 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Hexokinase GRAM PF02893.15 KXX78539.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 GRAM domain FA_desaturase PF00487.19 KXX78540.1 - 2.8e-39 135.1 25.5 4.1e-39 134.5 17.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KXX78540.1 - 1.9e-15 56.4 0.0 4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.3 KXX78541.1 - 4.4e-83 276.8 8.3 4.4e-83 276.8 5.7 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KXX78541.1 - 9e-46 154.2 0.0 1.1e-42 144.3 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KXX78541.1 - 1.2e-09 37.4 0.8 0.00013 21.7 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KXX78541.1 - 3.9e-06 27.1 7.6 0.0008 19.8 0.1 5.6 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 KXX78541.1 - 7.6e-06 26.1 2.8 0.02 15.1 0.0 4.7 5 1 0 5 5 5 2 HEAT repeats Arm PF00514.18 KXX78541.1 - 0.0032 17.2 0.0 0.83 9.5 0.0 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat THUMP PF02926.12 KXX78542.1 - 3.7e-09 36.5 0.0 7.2e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 THUMP domain TPP_enzyme_N PF02776.13 KXX78543.1 - 5.5e-35 120.3 0.1 2.2e-34 118.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KXX78543.1 - 3e-27 95.0 0.0 6.9e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KXX78543.1 - 4.5e-15 55.5 0.3 2.1e-14 53.3 0.0 2.2 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KXX78543.1 - 0.057 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SGT1 PF07093.6 KXX78544.1 - 3.6e-152 507.7 17.0 7.4e-151 503.4 11.8 2.0 1 1 0 1 1 1 1 SGT1 protein DUF2201_N PF13203.1 KXX78545.1 - 0.48 9.5 2.9 0.31 10.1 0.5 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain Sds3 PF08598.6 KXX78546.1 - 0.001 18.6 2.4 0.002 17.6 1.6 1.4 1 0 0 1 1 1 1 Sds3-like Rad60-SLD PF11976.3 KXX78546.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2431 PF10354.4 KXX78547.1 - 3.5e-45 153.9 0.0 2.9e-32 111.9 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) BSP_II PF05432.6 KXX78547.1 - 0.044 13.0 19.9 0.1 11.8 13.8 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 KXX78547.1 - 8.9 5.4 15.5 18 4.4 10.8 1.5 1 0 0 1 1 1 0 NOA36 protein NOA36 PF06524.7 KXX78548.1 - 0.028 13.7 7.0 0.047 12.9 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 KXX78548.1 - 0.044 13.3 5.8 0.081 12.5 4.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KXX78548.1 - 0.11 12.2 5.1 0.3 10.8 3.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 KXX78548.1 - 0.31 10.2 6.8 0.45 9.7 4.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KXX78548.1 - 0.52 8.1 6.9 0.73 7.6 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KXX78548.1 - 2.7 5.9 5.2 4.4 5.2 3.6 1.3 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.16 KXX78549.1 - 2.4e-11 43.5 0.0 3.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family DUF2841 PF11001.3 KXX78550.1 - 6e-36 123.0 1.2 9e-36 122.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HypA PF01155.14 KXX78550.1 - 0.099 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family ABC_membrane PF00664.18 KXX78551.1 - 1.5e-81 273.8 28.6 5.9e-45 153.8 8.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KXX78551.1 - 3.4e-52 176.3 1.0 1.4e-29 103.0 0.1 3.5 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KXX78551.1 - 1.3e-08 34.3 4.3 0.0048 16.1 0.0 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KXX78551.1 - 7.2e-05 22.7 0.1 0.58 10.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KXX78551.1 - 8.9e-05 21.7 0.2 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX78551.1 - 0.00028 20.9 1.4 0.21 11.5 0.1 3.1 4 0 0 4 4 2 2 AAA ATPase domain AAA_29 PF13555.1 KXX78551.1 - 0.00038 19.9 1.3 1 8.9 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KXX78551.1 - 0.00045 19.6 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KXX78551.1 - 0.00093 19.5 0.5 0.2 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KXX78551.1 - 0.0016 18.9 2.2 1.5 9.3 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein AAA_21 PF13304.1 KXX78551.1 - 0.0032 17.4 0.1 1.8 8.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KXX78551.1 - 0.0042 16.9 1.1 0.38 10.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 KXX78551.1 - 0.016 15.0 0.9 0.68 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KXX78551.1 - 0.016 14.6 0.2 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KXX78551.1 - 0.084 12.4 4.4 3.8 7.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain NACHT PF05729.7 KXX78551.1 - 0.09 12.4 0.7 0.42 10.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KXX78551.1 - 0.11 13.3 0.1 8.2 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 KXX78551.1 - 0.15 11.1 0.0 8 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KXX78551.1 - 0.16 12.1 0.7 16 5.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KXX78551.1 - 0.2 11.0 0.1 18 4.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KXX78551.1 - 0.5 9.4 1.5 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Microtub_assoc PF07989.6 KXX78552.1 - 4.2e-22 77.7 2.9 4.2e-22 77.7 2.0 11.8 10 3 3 13 13 13 1 Microtubule associated PACT_coil_coil PF10495.4 KXX78552.1 - 7.1e-07 29.0 0.8 7.1e-07 29.0 0.6 4.6 3 1 0 3 3 3 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TPR_MLP1_2 PF07926.7 KXX78552.1 - 0.0036 17.0 40.4 0.0046 16.7 9.4 13.0 2 1 6 11 11 11 6 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KXX78552.1 - 1.9 7.6 63.6 0.062 12.4 0.9 8.9 1 1 7 10 10 10 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KXX78552.1 - 2.4 6.5 154.4 0.25 9.7 14.4 7.0 1 1 4 6 6 6 0 AAA domain DUF4611 PF15387.1 KXX78553.1 - 0.026 14.6 3.0 3.4 7.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Takusan PF04822.8 KXX78553.1 - 0.031 14.0 0.5 0.086 12.6 0.4 1.7 1 0 0 1 1 1 0 Takusan GMC_oxred_N PF00732.14 KXX78554.1 - 7.7e-55 186.1 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX78554.1 - 3.4e-38 131.1 0.0 5.7e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX78554.1 - 1.6e-05 23.9 0.4 0.003 16.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX78554.1 - 0.0002 20.4 0.7 0.00035 19.6 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX78554.1 - 0.00053 19.9 0.1 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX78554.1 - 0.011 15.5 0.3 0.22 11.2 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KXX78554.1 - 0.011 14.6 0.4 0.15 10.8 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KXX78554.1 - 0.028 13.0 0.1 0.042 12.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 KXX78554.1 - 0.088 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain RseC_MucC PF04246.7 KXX78554.1 - 0.21 11.1 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC NAD_binding_10 PF13460.1 KXX78555.1 - 4.3e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX78555.1 - 5.6e-08 32.4 0.0 7.8e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KXX78555.1 - 0.00016 21.9 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KXX78555.1 - 0.00036 19.5 0.0 0.00066 18.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KXX78555.1 - 0.0055 15.9 0.0 0.0085 15.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KXX78555.1 - 0.007 16.2 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KXX78555.1 - 0.0099 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KXX78555.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 KR domain Myb_DNA-binding PF00249.26 KXX78556.1 - 7.4e-33 112.3 10.6 1.7e-11 43.9 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX78556.1 - 6.7e-32 109.3 10.5 6.4e-14 51.8 0.9 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 KXX78556.1 - 0.0048 16.7 6.8 0.99 9.3 0.1 3.4 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rubis-subs-bind PF09273.6 KXX78556.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Myb_DNA-bind_2 PF08914.6 KXX78556.1 - 0.14 11.9 1.6 4.5 7.1 0.0 3.2 3 1 0 3 3 3 0 Rap1 Myb domain MADF_DNA_bdg PF10545.4 KXX78556.1 - 1.2 9.3 5.1 4.9 7.4 0.1 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PAN_4 PF14295.1 KXX78557.1 - 1.2e-06 28.0 1.6 2.1e-06 27.3 1.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KXX78557.1 - 0.0047 16.6 0.3 0.0095 15.6 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KXX78557.1 - 0.037 13.8 1.4 0.071 12.9 1.0 1.4 1 0 0 1 1 1 0 PAN-like domain APH PF01636.18 KXX78558.1 - 3.2e-09 36.8 2.4 3.6e-09 36.6 0.7 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ferric_reduct PF01794.14 KXX78559.1 - 2.2e-15 56.8 13.9 2.2e-15 56.8 9.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KXX78559.1 - 2.1e-08 33.9 0.0 0.0042 16.9 0.0 2.7 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.7 KXX78559.1 - 3.1e-05 23.9 0.0 0.03 14.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain SR-25 PF10500.4 KXX78559.1 - 0.013 14.9 2.8 0.021 14.3 1.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF63 PF01889.12 KXX78559.1 - 0.13 12.2 5.2 0.048 13.7 1.9 1.4 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 WXG100 PF06013.7 KXX78561.1 - 0.17 11.9 0.4 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF208 PF02677.9 KXX78563.1 - 0.071 12.8 0.1 0.073 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 WD40 PF00400.27 KXX78564.1 - 7.2e-11 41.5 1.4 0.0085 15.9 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat SGL PF08450.7 KXX78564.1 - 0.0038 16.6 0.0 0.056 12.8 0.0 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region WD40 PF00400.27 KXX78565.1 - 3.8e-10 39.2 0.3 0.00067 19.4 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DOMON PF03351.12 KXX78565.1 - 0.029 14.2 1.1 0.074 12.9 0.8 1.6 1 0 0 1 1 1 0 DOMON domain DUF605 PF04652.11 KXX78565.1 - 0.35 10.2 22.7 0.26 10.6 3.2 2.2 2 0 0 2 2 2 0 Vta1 like Hydrolase_2 PF07486.7 KXX78567.1 - 0.063 13.7 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 Cell Wall Hydrolase GPAT_N PF14829.1 KXX78567.1 - 0.12 12.0 0.3 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal YbfN PF13982.1 KXX78567.1 - 0.21 11.7 1.3 3.9 7.7 0.0 2.7 3 0 0 3 3 3 0 YbfN-like lipoprotein AAA PF00004.24 KXX78568.1 - 2.3e-19 69.8 0.0 4.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX78568.1 - 1e-05 26.3 3.8 1.7e-05 25.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KXX78568.1 - 0.00042 19.4 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX78568.1 - 0.0015 18.5 0.0 0.005 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX78568.1 - 0.0021 18.2 0.3 0.013 15.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 KXX78568.1 - 0.0062 16.8 3.9 0.008 16.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX78568.1 - 0.023 14.4 0.2 0.063 13.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KXX78568.1 - 0.024 14.3 0.1 0.088 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KXX78568.1 - 0.055 12.9 0.0 0.71 9.3 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KXX78568.1 - 0.18 11.3 3.3 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.7 KXX78568.1 - 0.48 8.2 17.1 0.73 7.6 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sec62 PF03839.11 KXX78568.1 - 4.9 6.4 10.1 12 5.2 7.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 KXX78568.1 - 9.3 4.5 20.6 13 4.0 14.3 1.1 1 0 0 1 1 1 0 Daxx Family zf-RING_2 PF13639.1 KXX78569.1 - 2.2e-08 33.7 4.7 2.2e-08 33.7 3.2 2.0 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 KXX78569.1 - 0.00083 19.2 6.0 0.00083 19.2 4.1 2.0 2 1 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KXX78569.1 - 0.003 17.6 1.5 0.003 17.6 1.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger SWIM PF04434.12 KXX78569.1 - 0.0039 16.6 0.1 0.0083 15.5 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-Apc11 PF12861.2 KXX78569.1 - 0.013 15.2 1.9 0.013 15.2 1.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KXX78569.1 - 0.11 12.2 8.0 0.032 13.9 3.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX78569.1 - 0.4 10.7 8.7 0.11 12.5 3.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KXX78569.1 - 0.52 10.3 7.0 1.2 9.1 4.9 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 KXX78569.1 - 0.57 9.8 6.7 0.13 11.9 2.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 KXX78570.1 - 9.4e-24 83.7 42.2 7.8e-22 77.4 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrolase_6 PF13344.1 KXX78571.1 - 8.8e-08 31.9 0.0 2.4e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase p450 PF00067.17 KXX78572.1 - 5.1e-66 223.0 0.0 5.8e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KXX78573.1 - 1.8e-21 76.7 0.1 2.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX78573.1 - 5.1e-11 42.5 0.1 8.4e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX78573.1 - 9.6e-08 32.0 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX78573.1 - 0.00028 20.9 0.2 0.00061 19.8 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX78573.1 - 0.00049 19.5 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KXX78573.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3954 PF13128.1 KXX78573.1 - 0.16 11.4 0.0 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) Polysacc_synt_2 PF02719.10 KXX78573.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PUL PF08324.6 KXX78574.1 - 4.5e-56 189.5 0.0 5.8e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KXX78574.1 - 3.2e-43 146.4 0.1 5.6e-43 145.6 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KXX78574.1 - 3.1e-37 125.1 13.5 4.3e-07 29.5 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KXX78574.1 - 0.0014 18.3 0.2 15 5.4 0.0 4.6 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region NTP_transf_2 PF01909.18 KXX78575.1 - 1.2e-05 25.5 0.1 3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nuc-transf PF10127.4 KXX78575.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotidyltransferase Amidoligase_2 PF12224.3 KXX78576.1 - 7e-12 45.4 0.1 1.2e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme AAA PF00004.24 KXX78578.1 - 1.9e-07 31.3 0.1 5.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX78578.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KXX78578.1 - 0.11 13.2 0.1 0.36 11.6 0.0 1.8 1 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KXX78579.1 - 1.3e-44 152.4 67.2 7e-36 123.6 28.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX78579.1 - 4.4e-07 28.8 30.7 0.00019 20.1 3.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KXX78579.1 - 0.006 16.3 6.1 0.21 11.4 0.6 3.4 3 0 0 3 3 3 2 MFS_1 like family Acyl-CoA_dh_1 PF00441.19 KXX78580.1 - 8e-23 81.1 1.5 8e-23 81.1 1.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX78580.1 - 5.1e-11 41.9 0.1 1.4e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KXX78580.1 - 6.3e-09 36.4 0.8 1.4e-08 35.3 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX78580.1 - 5.6e-06 26.6 1.9 5.6e-06 26.6 1.3 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.17 KXX78581.1 - 9.1e-60 202.4 0.0 1.1e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRR1 PF07985.7 KXX78583.1 - 0.012 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 SRR1 WD40 PF00400.27 KXX78587.1 - 8.4e-34 114.2 2.1 3.6e-12 45.6 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat HET PF06985.6 KXX78589.1 - 1.4e-26 93.3 0.1 3.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Cellulase PF00150.13 KXX78590.1 - 0.00067 18.9 0.2 0.038 13.1 0.1 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HET PF06985.6 KXX78593.1 - 3.2e-18 66.2 0.1 5.2e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NPP1 PF05630.6 KXX78595.1 - 9e-79 264.0 0.9 1e-78 263.7 0.6 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 KXX78595.1 - 0.099 10.6 0.4 0.13 10.2 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) Mito_carr PF00153.22 KXX78596.1 - 1.3e-14 53.6 6.2 1.9e-10 40.2 0.1 3.8 3 1 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_23 PF13489.1 KXX78597.1 - 3.2e-21 75.7 0.0 4.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78597.1 - 3.9e-08 33.8 0.0 9.3e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78597.1 - 7.2e-07 28.9 0.0 1.4e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78597.1 - 1.7e-06 28.3 0.0 8.7e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78597.1 - 4.8e-06 26.9 0.0 4.4e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78597.1 - 8.3e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX78597.1 - 0.011 15.7 0.0 0.048 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KXX78597.1 - 0.017 15.1 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF3940 PF13076.1 KXX78597.1 - 0.06 12.8 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) Methyltransf_4 PF02390.12 KXX78597.1 - 0.13 11.2 0.0 0.72 8.8 0.0 2.1 2 1 0 2 2 2 0 Putative methyltransferase Rad4 PF03835.10 KXX78598.1 - 2.5e-11 43.1 2.4 3.8e-11 42.5 1.0 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KXX78598.1 - 1.4e-07 31.6 1.3 3e-07 30.6 0.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ogr_Delta PF04606.7 KXX78598.1 - 0.12 12.1 1.6 0.27 10.9 1.1 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger YdjO PF14169.1 KXX78598.1 - 0.36 10.3 4.8 4.2 6.8 0.2 2.4 1 1 1 2 2 2 0 Cold-inducible protein YdjO E1-E2_ATPase PF00122.15 KXX78600.1 - 9.2e-51 172.0 4.9 1.5e-50 171.3 3.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX78600.1 - 7.2e-28 98.4 0.3 1.4e-27 97.5 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX78600.1 - 1.7e-13 51.1 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KXX78600.1 - 6.9e-05 22.9 1.3 0.00021 21.3 0.0 2.5 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KXX78600.1 - 0.00042 19.9 0.6 0.01 15.4 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KXX78601.1 - 3.1e-41 141.2 0.0 1.8e-37 128.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78601.1 - 1.2e-13 50.7 0.0 8.5e-08 31.5 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 KXX78601.1 - 0.00069 19.4 0.0 0.066 12.9 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX78601.1 - 0.0025 16.8 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Helicase_C_2 PF13307.1 KXX78602.1 - 7.4e-55 185.4 0.0 2.1e-54 183.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KXX78602.1 - 6.2e-46 155.9 0.0 1.3e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KXX78602.1 - 0.0058 16.4 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit BetR PF08667.5 KXX78602.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 BetR domain SNF2_N PF00176.18 KXX78602.1 - 0.084 11.6 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.1 KXX78602.1 - 0.14 12.3 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Lectin_C PF00059.16 KXX78605.1 - 0.013 16.1 0.0 0.93 10.1 0.0 2.1 1 1 1 2 2 2 0 Lectin C-type domain Glyco_hydro_2_N PF02837.13 KXX78609.1 - 1.5e-36 125.5 0.2 9.2e-36 122.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KXX78609.1 - 8.7e-29 100.3 0.0 7.1e-28 97.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KXX78609.1 - 1e-12 48.4 0.0 2.7e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KXX78609.1 - 0.00011 22.4 0.1 0.0013 19.0 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 KXX78609.1 - 0.032 14.1 0.4 0.09 12.6 0.3 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF3632 PF12311.3 KXX78610.1 - 1.1e-29 103.6 2.5 1.4e-29 103.1 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ferric_reduct PF01794.14 KXX78611.1 - 1 9.4 11.6 2.7 8.1 8.1 1.7 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Macoilin PF09726.4 KXX78613.1 - 0.004 15.5 0.3 0.0042 15.4 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein MRP-S31 PF15433.1 KXX78613.1 - 0.0099 15.3 1.5 0.013 14.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 BssS PF13991.1 KXX78613.1 - 0.036 13.7 0.7 0.13 12.0 0.2 2.1 2 0 0 2 2 2 0 BssS protein family DUF3584 PF12128.3 KXX78613.1 - 0.048 10.9 6.0 0.061 10.6 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KXX78613.1 - 0.078 12.5 1.8 0.1 12.1 1.3 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KXX78613.1 - 0.083 11.9 4.7 0.11 11.4 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KXX78613.1 - 0.13 12.0 5.8 0.19 11.4 4.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 KXX78613.1 - 0.41 10.6 14.7 2.7 7.9 0.6 2.4 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Prp19 PF08606.6 KXX78613.1 - 0.71 9.6 6.2 0.07 12.8 0.8 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like TMF_TATA_bd PF12325.3 KXX78613.1 - 1.2 8.8 9.0 12 5.6 6.2 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1635 PF07795.6 KXX78613.1 - 1.7 7.9 5.8 6.3 6.1 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Atg14 PF10186.4 KXX78613.1 - 5.7 5.7 7.6 8.2 5.2 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Acetyltransf_1 PF00583.19 KXX78615.1 - 9.7e-05 22.3 0.0 0.00027 20.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Ank_4 PF13637.1 KXX78615.1 - 0.00057 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78615.1 - 0.00074 19.5 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 KXX78615.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX78615.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.1 KXX78615.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX78615.1 - 0.0016 18.1 0.1 0.0094 15.6 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Ank PF00023.25 KXX78615.1 - 0.0023 17.6 0.1 0.0069 16.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_CG PF14542.1 KXX78615.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KXX78615.1 - 0.12 12.5 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.17 KXX78617.1 - 0.0046 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Kinesin PF00225.18 KXX78618.1 - 9e-57 192.2 0.0 1.8e-56 191.2 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Jnk-SapK_ap_N PF09744.4 KXX78618.1 - 0.0048 16.8 1.6 0.0048 16.8 1.1 1.8 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 HALZ PF02183.13 KXX78618.1 - 1.5 8.5 4.3 0.33 10.7 0.3 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Kinetocho_Slk19 PF12709.2 KXX78618.1 - 4.7 7.3 6.4 4.7 7.3 0.2 2.4 2 0 0 2 2 2 0 Central kinetochore-associated Tyrosinase PF00264.15 KXX78619.1 - 3.6e-35 122.1 0.0 4.6e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase adh_short PF00106.20 KXX78620.1 - 2.5e-14 53.5 1.0 4.7e-12 46.1 0.1 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KXX78620.1 - 5.6e-09 36.1 0.4 6.6e-09 35.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX78620.1 - 0.0023 17.6 0.5 0.07 12.7 0.0 2.3 1 1 1 2 2 2 2 KR domain LMWPc PF01451.16 KXX78622.1 - 0.0061 16.8 0.0 3.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase BCLP PF12304.3 KXX78624.1 - 0.02 14.3 0.5 0.02 14.3 0.3 2.6 2 1 0 2 2 2 0 Beta-casein like protein Na_Ca_ex PF01699.19 KXX78624.1 - 1.3 8.6 12.5 0.73 9.4 0.4 3.0 2 1 0 2 2 2 0 Sodium/calcium exchanger protein DUF1705 PF08019.7 KXX78624.1 - 7.6 6.0 12.7 8.8 5.8 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Esterase PF00756.15 KXX78625.1 - 9.5e-08 31.7 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KXX78625.1 - 5.3e-07 29.7 0.0 7.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX78625.1 - 3.8e-05 23.0 0.0 6.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX78625.1 - 0.059 13.1 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PLDc_N PF13396.1 KXX78626.1 - 4.4e-13 48.6 4.5 5.9e-13 48.2 3.1 1.2 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Glucos_trans_II PF14264.1 KXX78626.1 - 0.0077 15.2 1.0 0.0084 15.1 0.7 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII MpPF26 PF07666.6 KXX78626.1 - 0.026 14.4 0.6 0.028 14.2 0.4 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 Pox_A14 PF05767.7 KXX78626.1 - 0.029 14.3 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3309 PF11752.3 KXX78626.1 - 0.041 13.6 1.4 0.041 13.6 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3671 PF12420.3 KXX78626.1 - 0.058 13.3 0.4 0.72 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function Chs3p PF12271.3 KXX78626.1 - 0.086 11.8 1.9 0.11 11.3 1.3 1.1 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit DUF3951 PF13131.1 KXX78626.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Cation_ATPase_C PF00689.16 KXX78626.1 - 0.14 11.6 3.6 0.19 11.2 2.5 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.4 KXX78626.1 - 0.15 10.5 0.5 0.19 10.2 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 KXX78626.1 - 0.67 9.7 3.7 1.2 8.8 2.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF1996 PF09362.5 KXX78630.1 - 7.5e-56 189.4 0.8 4.1e-55 186.9 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) Gly_transf_sug PF04488.10 KXX78632.1 - 0.016 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif DUF2781 PF10914.3 KXX78633.1 - 6.3e-33 113.6 9.9 7.2e-33 113.4 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ApbA PF02558.11 KXX78634.1 - 1.4e-24 86.2 0.0 2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KXX78634.1 - 7.8e-10 38.8 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF466 PF04328.8 KXX78634.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF466) ABC_tran PF00005.22 KXX78635.1 - 5.3e-24 85.0 0.0 1.9e-10 41.1 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX78635.1 - 1.8e-11 44.5 0.1 0.003 17.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KXX78635.1 - 6.2e-08 33.4 0.0 0.011 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KXX78635.1 - 5e-07 29.5 0.0 0.0028 17.5 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KXX78635.1 - 1.1e-05 24.8 0.0 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX78635.1 - 0.00025 21.1 0.1 0.37 10.9 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.1 KXX78635.1 - 0.0013 19.0 0.0 0.045 14.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KXX78635.1 - 0.0014 18.5 0.0 2.6 7.9 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KXX78635.1 - 0.0034 17.2 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KXX78635.1 - 0.0037 16.7 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KXX78635.1 - 0.0042 16.5 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 KXX78635.1 - 0.0042 17.5 0.0 0.47 10.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 KXX78635.1 - 0.0067 15.8 0.1 0.23 10.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KXX78635.1 - 0.0094 15.6 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KXX78635.1 - 0.026 14.4 0.7 2.1 8.3 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.12 KXX78635.1 - 0.049 13.1 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KXX78635.1 - 0.05 13.0 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KXX78635.1 - 0.065 13.5 0.0 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KXX78635.1 - 0.068 12.3 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 KXX78635.1 - 0.075 13.2 0.1 0.55 10.4 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KXX78635.1 - 0.082 13.0 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 KXX78635.1 - 0.11 11.3 0.0 8.3 5.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 KXX78635.1 - 0.25 10.9 0.0 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KXX78635.1 - 0.25 9.7 0.0 0.38 9.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain UMP1 PF05348.6 KXX78636.1 - 3.6e-24 85.1 0.0 4.1e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 KXX78637.1 - 4.2e-09 36.2 0.0 1.1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KXX78637.1 - 3.8e-05 23.8 0.2 9.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KXX78637.1 - 0.026 13.9 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Adaptin_N PF01602.15 KXX78638.1 - 9.6e-135 449.8 11.2 1.2e-134 449.5 7.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KXX78638.1 - 3.8e-19 69.2 0.1 3.8e-19 69.2 0.1 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KXX78638.1 - 1.9e-17 63.3 4.7 1.1e-10 41.6 0.2 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 KXX78638.1 - 5.4e-12 44.7 2.7 9.7e-05 22.1 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KXX78638.1 - 2e-07 31.2 3.0 0.013 15.9 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 KXX78638.1 - 7.1e-05 22.2 1.3 0.13 11.6 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KXX78638.1 - 0.00011 21.8 0.7 1.3 8.9 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KXX78638.1 - 0.0029 17.2 0.0 0.4 10.4 0.0 3.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain T_hemolysin PF12261.3 KXX78638.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin DUF1077 PF06417.7 KXX78639.1 - 2.7e-55 185.0 3.3 3.5e-55 184.7 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF2360 PF10152.4 KXX78639.1 - 1.2 9.3 3.6 2.1 8.6 2.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MARVEL PF01284.18 KXX78640.1 - 3.8e-20 72.1 1.9 5.4e-20 71.6 1.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Chitin_synth_1 PF01644.12 KXX78641.1 - 3.7e-85 283.7 0.4 6.2e-85 282.9 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KXX78641.1 - 4.5e-33 112.7 0.1 9.8e-33 111.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KXX78641.1 - 2.6e-22 78.9 6.1 9.6e-20 70.4 0.0 2.4 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KXX78641.1 - 1.3e-09 38.0 0.6 1.3e-09 38.0 0.4 2.1 1 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX78641.1 - 9.2e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NIR_SIR PF01077.17 KXX78642.1 - 3.8e-54 182.3 0.8 1.7e-47 160.6 0.0 2.7 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KXX78642.1 - 6.7e-32 108.9 0.0 2.7e-16 58.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KXX78642.1 - 1.7e-29 102.6 0.0 4.4e-29 101.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KXX78642.1 - 1.1e-07 31.6 0.1 6.5e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KXX78643.1 - 9.7e-52 175.3 2.7 1.2e-51 175.0 1.8 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_M56 PF05569.6 KXX78643.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 ABC2_membrane_2 PF12679.2 KXX78643.1 - 0.41 9.4 6.6 0.55 9.0 4.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sugar_tr PF00083.19 KXX78644.1 - 1.3e-96 323.9 26.4 1.5e-96 323.7 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX78644.1 - 4.5e-30 104.5 52.1 3.7e-28 98.2 19.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX78644.1 - 1.6e-06 26.5 1.0 1.6e-06 26.5 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KXX78645.1 - 1e-30 106.6 56.6 5.9e-30 104.1 39.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX78645.1 - 1.3e-15 56.6 12.8 1.3e-15 56.6 8.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_31 PF01055.21 KXX78646.1 - 2.9e-113 379.0 0.1 3.6e-113 378.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KXX78646.1 - 1.2e-17 63.4 0.5 3.8e-17 61.8 0.0 2.2 3 0 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.16 KXX78647.1 - 1.2e-65 221.5 0.0 1.6e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX78647.1 - 1.2e-59 201.6 0.1 2e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX78647.1 - 2.4e-22 78.6 2.2 2.7e-22 78.4 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.13 KXX78647.1 - 0.0024 17.8 1.3 0.0024 17.8 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF11 Sugar-bind PF04198.8 KXX78647.1 - 0.013 14.4 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain ETF PF01012.16 KXX78647.1 - 0.041 13.5 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain LemA PF04011.7 KXX78648.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 LemA family TIP41 PF04176.8 KXX78649.1 - 1.4e-67 226.5 0.0 1.7e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 KXX78650.1 - 6.7e-72 241.7 0.0 8.4e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78650.1 - 2.8e-44 151.1 0.0 3.6e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX78650.1 - 3.2e-07 29.6 0.0 1.4e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KXX78650.1 - 0.00043 19.3 0.1 0.00071 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KXX78650.1 - 0.014 14.7 0.0 0.048 12.9 0.0 1.8 2 1 1 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.4 KXX78650.1 - 0.027 13.7 0.0 0.047 13.0 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KXX78650.1 - 0.029 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 KXX78651.1 - 1.1e-64 217.0 0.4 1.4e-64 216.6 0.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KXX78651.1 - 0.001 18.7 0.5 0.001 18.7 0.3 1.6 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KXX78651.1 - 0.05 13.6 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M24 PF00557.19 KXX78652.1 - 7.1e-44 149.8 0.0 1.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KXX78652.1 - 4.8e-26 91.7 0.0 4.3e-21 75.7 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain FUN14 PF04930.10 KXX78653.1 - 1.5e-06 28.3 4.6 1.1e-05 25.5 3.2 2.0 1 1 0 1 1 1 1 FUN14 family CBFD_NFYB_HMF PF00808.18 KXX78654.1 - 1.2e-19 70.0 0.6 2e-19 69.4 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX78654.1 - 1.6e-11 44.1 0.1 2.9e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KXX78654.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 KXX78655.1 - 4.4e-28 97.2 0.0 7.1e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_60s PF00428.14 KXX78655.1 - 0.042 14.2 2.3 0.096 13.0 1.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sec15 PF04091.7 KXX78657.1 - 1.4e-111 372.7 1.1 3.9e-111 371.3 0.8 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 KXX78657.1 - 0.0024 17.3 1.5 0.0071 15.7 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DASH_Duo1 PF08651.5 KXX78657.1 - 0.058 12.9 2.8 0.14 11.7 0.7 2.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 COG2 PF06148.6 KXX78657.1 - 2.5 7.9 10.8 2.4 8.0 1.1 4.0 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Sad1_UNC PF07738.8 KXX78658.1 - 3e-36 124.1 0.0 4.6e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal tRNA-synt_1b PF00579.20 KXX78659.1 - 4.3e-71 239.4 0.0 6.2e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 KXX78659.1 - 1.8e-22 78.9 0.0 5e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RRM_2 PF04059.7 KXX78660.1 - 2.2e-36 123.6 0.3 4.5e-36 122.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 KXX78660.1 - 0.00015 21.2 0.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX78660.1 - 0.00041 20.2 0.0 0.3 11.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_61 PF03443.9 KXX78663.1 - 8.5e-51 172.8 0.4 1e-50 172.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_6 PF12697.2 KXX78664.1 - 5.6e-13 49.2 4.7 8.4e-13 48.7 3.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78664.1 - 8.6e-13 48.2 0.3 1.2e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX78664.1 - 1.1e-07 31.7 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KXX78664.1 - 2.7e-05 23.8 0.2 3.9e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX78664.1 - 0.0055 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KXX78664.1 - 0.016 14.6 0.2 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF218 PF02698.12 KXX78664.1 - 0.017 14.6 0.0 0.12 11.8 0.0 2.2 1 1 0 1 1 1 0 DUF218 domain Cutinase PF01083.17 KXX78664.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cutinase MFS_1 PF07690.11 KXX78666.1 - 1.8e-31 109.1 65.9 1.7e-20 73.0 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX78666.1 - 0.0011 17.6 33.7 0.0025 16.4 12.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 KXX78666.1 - 0.052 12.0 24.3 0.016 13.7 13.4 2.5 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like CTD PF12815.2 KXX78667.1 - 2.1e-25 89.5 53.3 2.1e-20 73.3 25.5 5.2 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KXX78667.1 - 7e-25 86.5 0.0 1.2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KXX78667.1 - 3.2e-18 66.1 11.1 3.2e-18 66.1 7.7 4.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KXX78667.1 - 1.3e-06 27.8 15.3 9e-05 22.0 0.4 5.1 6 0 0 6 6 6 2 KOW motif Abhydrolase_6 PF12697.2 KXX78668.1 - 3.3e-25 89.3 1.9 5.1e-25 88.7 1.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78668.1 - 2.6e-12 46.7 0.0 4.8e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX78668.1 - 1.4e-10 41.1 0.0 2.4e-08 33.8 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.7 KXX78668.1 - 0.005 16.5 0.0 1.5 8.5 0.0 2.5 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 KXX78668.1 - 0.0057 15.5 0.2 0.0084 15.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 KXX78668.1 - 0.043 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 KXX78668.1 - 0.077 12.5 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KXX78668.1 - 0.078 13.1 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.5 KXX78668.1 - 0.088 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Hint_2 PF13403.1 KXX78668.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Hint domain PGAP1 PF07819.8 KXX78668.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein NMT_C PF02799.10 KXX78669.1 - 1.9e-79 265.4 0.0 2.8e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KXX78669.1 - 7.1e-62 207.7 0.0 1.1e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KXX78669.1 - 6.6e-05 22.7 0.1 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX78669.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain eIF3_subunit PF08597.5 KXX78669.1 - 0.042 13.3 12.8 0.086 12.3 8.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PGA2 PF07543.7 KXX78669.1 - 0.48 10.2 9.9 0.87 9.3 6.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4407 PF14362.1 KXX78669.1 - 3.9 6.3 8.7 5.3 5.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TATR PF03430.8 KXX78669.1 - 5.4 5.5 5.4 7.9 4.9 3.7 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator AA_permease_2 PF13520.1 KXX78671.1 - 8.2e-79 265.1 26.3 1e-78 264.8 18.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX78671.1 - 7.9e-13 47.5 19.0 1.2e-12 46.9 13.1 1.3 1 1 0 1 1 1 1 Amino acid permease Cyd_oper_YbgE PF09600.5 KXX78671.1 - 0.0043 17.1 4.8 0.0043 17.1 3.3 2.7 3 0 0 3 3 3 1 Cyd operon protein YbgE (Cyd_oper_YbgE) FGGY_C PF02782.11 KXX78672.1 - 3.5e-26 92.0 0.0 1.1e-25 90.3 0.0 2.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KXX78672.1 - 2.4e-22 79.4 0.0 1.9e-13 50.3 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF2424 PF10340.4 KXX78672.1 - 3.2e-08 32.6 0.0 2.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KXX78672.1 - 8.1e-08 32.0 0.2 7.8e-07 28.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX78672.1 - 0.31 9.6 0.1 0.48 9.0 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family CBFD_NFYB_HMF PF00808.18 KXX78673.1 - 2.1e-12 46.9 1.7 3.3e-12 46.2 1.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX78673.1 - 7.5e-05 22.7 0.2 0.00013 21.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mcm10 PF09332.6 KXX78673.1 - 0.036 13.3 3.6 0.075 12.3 2.5 1.5 1 0 0 1 1 1 0 Mcm10 replication factor Cyclin_C PF02984.14 KXX78673.1 - 0.93 9.4 4.3 0.4 10.6 0.8 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain PI3_PI4_kinase PF00454.22 KXX78674.1 - 1.4e-31 109.7 0.0 2.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KXX78674.1 - 1.1e-19 69.9 0.0 2.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Cep57_MT_bd PF06657.8 KXX78674.1 - 0.092 12.7 0.1 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Tad PF13400.1 KXX78674.1 - 0.49 10.4 4.2 9.5 6.3 0.4 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Pribosyl_synth PF14572.1 KXX78675.1 - 4.2e-43 147.2 3.8 8.5e-37 126.6 1.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KXX78675.1 - 1.9e-28 98.5 0.0 8.7e-28 96.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KXX78675.1 - 5.5e-11 42.2 0.6 1.4e-10 40.9 0.4 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KXX78675.1 - 0.099 11.8 0.3 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.27 KXX78676.1 - 4.9e-34 114.9 7.7 5.7e-07 29.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KXX78676.1 - 1.4e-08 34.6 0.1 7.8e-05 22.4 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A M16C_assoc PF08367.6 KXX78677.1 - 1.2e-54 184.7 0.0 1.8e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KXX78677.1 - 1.2e-35 122.8 0.0 3.8e-20 72.3 0.0 3.4 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KXX78677.1 - 7.9e-08 32.1 0.0 1.1e-06 28.5 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) HHH_8 PF14716.1 KXX78677.1 - 0.063 13.4 0.0 0.38 10.9 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain Orn_Arg_deC_N PF02784.11 KXX78678.1 - 1.2e-77 260.5 0.0 1.6e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KXX78678.1 - 1.1e-31 108.8 0.1 3.7e-31 107.2 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Taxilin PF09728.4 KXX78679.1 - 1.6e-88 296.7 57.7 4.7e-60 203.2 27.3 2.1 2 0 0 2 2 2 2 Myosin-like coiled-coil protein DUF904 PF06005.7 KXX78679.1 - 0.0036 17.5 11.0 0.0036 17.5 7.6 5.3 3 2 2 5 5 5 2 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 KXX78679.1 - 0.056 13.1 50.4 0.44 10.2 10.3 4.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 KXX78679.1 - 5.3 7.3 17.5 0.61 10.3 2.3 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 KXX78679.1 - 8.8 4.6 46.9 0.37 9.1 12.3 2.1 1 1 1 2 2 2 0 AAA domain MarR_2 PF12802.2 KXX78680.1 - 0.073 12.7 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 MarR family M_domain PF12938.2 KXX78680.1 - 7.5 6.2 6.9 15 5.3 4.8 1.5 1 0 0 1 1 1 0 M domain of GW182 Acetyltransf_1 PF00583.19 KXX78681.1 - 2.4e-18 65.9 0.0 3.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX78681.1 - 3.1e-08 33.6 0.1 7.4e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX78681.1 - 5.7e-07 29.2 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KXX78681.1 - 9e-06 25.8 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX78681.1 - 1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KXX78681.1 - 1.7e-05 24.8 0.7 3.9e-05 23.6 0.1 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX78681.1 - 3.8e-05 23.5 0.1 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMO PF03060.10 KXX78683.1 - 2.9e-68 230.4 2.5 3.5e-68 230.1 1.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KXX78683.1 - 2.2e-05 23.5 0.0 0.096 11.5 0.5 2.5 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX78683.1 - 0.0037 16.1 6.0 0.0067 15.3 4.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Zw10 PF06248.8 KXX78685.1 - 5.1e-10 38.1 4.1 1.3e-08 33.5 0.8 2.5 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KXX78685.1 - 0.0089 15.2 0.1 0.047 12.8 0.0 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal DUF964 PF06133.6 KXX78685.1 - 0.017 15.1 1.7 3.4 7.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF964) Ribosomal_L36e PF01158.13 KXX78686.1 - 1.3e-40 137.3 4.7 1.5e-40 137.1 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KXX78686.1 - 0.041 12.9 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 KXX78686.1 - 0.14 11.9 0.7 0.17 11.6 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Mei5 PF10376.4 KXX78686.1 - 0.17 11.4 1.7 0.31 10.5 0.1 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein UQ_con PF00179.21 KXX78687.1 - 4.3e-23 81.3 0.0 6.4e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX78687.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 KXX78687.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-DHHC PF01529.15 KXX78688.1 - 1e-42 145.4 7.7 1.7e-42 144.8 5.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4134 PF13572.1 KXX78688.1 - 0.008 16.2 0.5 0.015 15.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) DZR PF12773.2 KXX78688.1 - 5.3 6.9 13.6 0.11 12.3 4.6 1.8 2 0 0 2 2 2 0 Double zinc ribbon PI-PLC-X PF00388.14 KXX78689.1 - 5.7e-58 194.4 0.0 1.2e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KXX78689.1 - 2.2e-38 130.8 0.0 4.9e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KXX78689.1 - 6.6e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 KXX78689.1 - 0.00056 19.8 0.0 0.0024 17.8 0.0 2.1 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.12 KXX78689.1 - 0.0031 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SMC_N PF02463.14 KXX78690.1 - 6.4e-60 202.1 0.4 4.7e-59 199.2 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KXX78690.1 - 1.9e-26 92.3 0.0 8.8e-26 90.2 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KXX78690.1 - 1.2e-10 42.1 24.8 1.2e-10 42.1 17.2 6.4 2 2 3 5 5 2 1 AAA domain AAA_21 PF13304.1 KXX78690.1 - 5.5e-10 39.6 11.5 4e-05 23.7 0.5 3.7 3 2 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 KXX78690.1 - 9.4e-09 34.8 22.2 0.019 14.1 1.7 5.5 4 1 2 6 6 6 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 KXX78690.1 - 2.6e-08 33.2 0.0 5.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 KXX78690.1 - 6.4e-05 20.5 39.6 6.4e-05 20.5 27.5 4.9 3 2 1 5 5 5 3 Protein of unknown function (DUF3584) SbcCD_C PF13558.1 KXX78690.1 - 0.0034 17.2 0.0 0.031 14.1 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.6 KXX78690.1 - 0.0059 16.4 107.7 0.64 9.8 1.2 7.0 3 2 4 7 7 7 5 Autophagy protein 16 (ATG16) ADIP PF11559.3 KXX78690.1 - 0.0084 16.0 4.6 0.0084 16.0 3.2 9.1 4 2 3 9 9 8 3 Afadin- and alpha -actinin-Binding IncA PF04156.9 KXX78690.1 - 0.031 13.8 120.4 0.04 13.5 10.6 6.8 3 2 3 6 6 5 0 IncA protein AAA_13 PF13166.1 KXX78690.1 - 0.12 10.8 105.2 0.18 10.2 19.6 6.4 4 2 1 5 5 5 0 AAA domain Spc7 PF08317.6 KXX78690.1 - 0.24 9.9 104.0 0.27 9.8 10.8 6.9 3 2 4 8 8 7 0 Spc7 kinetochore protein AAA_22 PF13401.1 KXX78690.1 - 0.44 10.6 3.8 10 6.3 0.0 4.4 4 1 0 4 4 4 0 AAA domain DUF869 PF05911.6 KXX78690.1 - 0.47 8.6 99.7 0.63 8.1 21.0 4.5 3 2 1 4 4 4 0 Plant protein of unknown function (DUF869) ABC_tran PF00005.22 KXX78690.1 - 0.77 10.0 0.0 0.77 10.0 0.0 7.0 4 3 0 4 4 2 0 ABC transporter DUF948 PF06103.6 KXX78690.1 - 0.99 9.3 31.7 0.1 12.4 1.4 5.9 4 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KXX78690.1 - 1 9.1 29.1 0.31 10.8 0.1 7.0 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 KXX78690.1 - 3.1 7.1 113.0 1.1 8.6 7.3 7.2 3 2 4 7 7 7 0 Intermediate filament protein LPP PF04728.8 KXX78690.1 - 6.4 6.6 15.7 1.1 9.0 0.9 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF2838 PF10998.3 KXX78691.1 - 2.4e-46 156.2 10.7 2.4e-46 156.2 7.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Tropomyosin PF00261.15 KXX78691.1 - 0.057 12.5 2.2 0.09 11.8 1.5 1.2 1 0 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.2 KXX78691.1 - 0.058 13.2 0.9 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.4 KXX78691.1 - 0.23 10.3 0.7 0.35 9.7 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KXX78691.1 - 0.33 10.5 1.7 0.53 9.8 1.2 1.2 1 0 0 1 1 1 0 IncA protein Glyco_transf_41 PF13844.1 KXX78692.1 - 4.4e-97 324.9 0.0 9.2e-47 159.0 0.0 4.0 3 1 1 4 4 4 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KXX78692.1 - 3.9e-24 84.0 5.3 2.9e-07 30.0 0.2 4.9 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KXX78692.1 - 3.2e-22 77.1 5.0 8.9e-06 25.0 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78692.1 - 2.4e-19 67.6 6.6 0.00091 18.9 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KXX78692.1 - 5.5e-15 55.0 4.9 5.7e-07 29.3 0.1 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX78692.1 - 5e-13 47.8 0.8 0.015 15.0 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78692.1 - 8.2e-11 42.2 2.8 0.038 14.6 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KXX78692.1 - 3.1e-10 39.4 0.8 0.013 15.6 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KXX78692.1 - 8.2e-10 38.2 8.2 0.023 14.6 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX78692.1 - 1.4e-08 34.6 8.6 0.001 19.5 0.1 6.6 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX78692.1 - 3e-07 29.7 3.7 0.057 13.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KXX78692.1 - 0.00023 21.3 1.3 4.1 8.0 0.3 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX78692.1 - 0.00042 20.6 4.0 7.4 6.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX78692.1 - 0.0014 18.7 3.3 0.064 13.3 0.1 3.1 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX78692.1 - 0.019 14.7 1.6 2.9 7.7 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 KXX78692.1 - 0.11 12.5 0.8 0.53 10.3 0.0 2.6 4 0 0 4 4 2 0 Tetratrico peptide repeat BTAD PF03704.12 KXX78692.1 - 0.17 12.1 3.2 13 6.0 0.0 3.3 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Sel1 PF08238.7 KXX78692.1 - 0.42 11.3 4.9 15 6.4 0.2 3.5 3 1 0 3 3 3 0 Sel1 repeat Ribosomal_L11_N PF03946.9 KXX78693.1 - 1.2e-10 40.7 0.1 2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KXX78693.1 - 1.2e-07 31.7 0.1 2.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 KXX78693.1 - 0.012 15.2 0.0 0.073 12.7 0.0 2.2 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region DNA_pol_lambd_f PF10391.4 KXX78694.1 - 4.3e-22 77.4 0.7 8.4e-22 76.4 0.5 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 KXX78694.1 - 1.5e-20 73.2 0.0 2.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KXX78694.1 - 4e-18 64.8 0.0 8.5e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KXX78694.1 - 6.7e-13 48.6 0.0 1.5e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KXX78694.1 - 0.0016 18.5 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KXX78694.1 - 0.011 15.9 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain TFIIE_alpha PF02002.12 KXX78695.1 - 2.4e-16 59.1 0.2 4.5e-16 58.2 0.2 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 KXX78695.1 - 0.0063 15.8 0.3 0.019 14.2 0.2 1.8 1 1 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 KXX78695.1 - 0.016 14.6 2.9 2.2 7.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Nudix_N_2 PF14803.1 KXX78695.1 - 0.018 14.6 0.5 0.072 12.7 0.2 2.2 2 0 0 2 2 2 0 Nudix N-terminal SnAC PF14619.1 KXX78695.1 - 0.044 13.9 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DZR PF12773.2 KXX78695.1 - 0.054 13.3 0.7 0.14 11.9 0.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF2387 PF09526.5 KXX78695.1 - 0.058 13.3 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 KXX78695.1 - 0.13 12.2 0.6 0.4 10.6 0.4 1.9 1 0 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KXX78695.1 - 0.13 11.4 1.8 8.1 5.7 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Sec23_trunk PF04811.10 KXX78696.1 - 1.7e-80 269.9 0.0 2.3e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KXX78696.1 - 4.4e-34 116.0 1.2 9.3e-34 114.9 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KXX78696.1 - 2e-30 105.1 0.2 4.2e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KXX78696.1 - 3.1e-16 58.6 6.5 6.4e-16 57.6 4.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KXX78696.1 - 5.2e-14 51.6 0.0 1.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat MAPEG PF01124.13 KXX78697.1 - 4.8e-22 77.9 2.3 5.8e-22 77.6 1.6 1.1 1 0 0 1 1 1 1 MAPEG family WD40 PF00400.27 KXX78699.1 - 2.4e-184 591.4 59.8 2.9e-14 52.3 0.2 16.4 16 0 0 16 16 16 16 WD domain, G-beta repeat Nup160 PF11715.3 KXX78699.1 - 3.7e-19 68.2 52.5 0.017 13.2 0.2 13.2 1 1 9 12 12 12 12 Nucleoporin Nup120/160 PD40 PF07676.7 KXX78699.1 - 2.9e-12 45.9 37.3 7.5 6.3 0.0 15.4 16 0 0 16 16 16 3 WD40-like Beta Propeller Repeat NACHT PF05729.7 KXX78699.1 - 1.6e-11 44.1 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KXX78699.1 - 1.1e-09 37.1 11.5 0.031 12.5 0.0 6.1 3 2 4 7 7 7 5 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KXX78699.1 - 1.1e-06 27.8 14.6 16 4.9 0.1 11.2 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature YopE_N PF09020.5 KXX78699.1 - 5.2e-05 23.2 0.3 3.6 7.6 0.0 4.7 4 2 0 4 4 4 2 YopE, N terminal DUF1258 PF06869.7 KXX78699.1 - 0.00017 20.7 5.5 4.4 6.3 0.0 6.4 3 2 4 7 7 7 1 Protein of unknown function (DUF1258) PEGA PF08308.6 KXX78699.1 - 0.0031 17.2 0.0 0.21 11.4 0.0 3.9 4 0 0 4 4 4 1 PEGA domain GATase PF00117.23 KXX78699.1 - 0.051 13.0 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Myb_DNA-binding PF00249.26 KXX78701.1 - 0.013 15.5 1.6 0.013 15.4 0.1 1.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain DnaJ PF00226.26 KXX78701.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.6 2 0 0 2 2 2 0 DnaJ domain Bclx_interact PF08945.5 KXX78702.1 - 0.11 12.0 0.1 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Acetyltransf_13 PF13880.1 KXX78702.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF1254 PF06863.7 KXX78703.1 - 0.093 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) RhoGAP PF00620.22 KXX78704.1 - 2.1e-44 150.7 0.6 4.2e-44 149.8 0.3 1.6 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 KXX78704.1 - 3.9e-09 36.6 0.0 8.8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KXX78704.1 - 4.8e-06 26.7 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KXX78704.1 - 0.088 12.8 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain GOLGA2L5 PF15070.1 KXX78704.1 - 0.44 8.9 6.4 0.035 12.6 1.1 1.5 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Fungal_trans PF04082.13 KXX78705.1 - 2e-06 26.8 0.0 3.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78705.1 - 2.9e-06 27.0 11.0 5.1e-06 26.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1777 PF08648.7 KXX78705.1 - 0.0044 16.7 5.4 0.011 15.4 3.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MCM PF00493.18 KXX78706.1 - 9.9e-134 445.3 0.3 1.8e-133 444.4 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KXX78706.1 - 1.9e-26 92.9 0.2 1.5e-25 89.9 0.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX78706.1 - 1.5e-07 30.7 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX78706.1 - 1.4e-06 28.0 0.2 7.6e-06 25.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 KXX78706.1 - 0.0044 17.3 0.1 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KXX78706.1 - 0.027 14.0 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KXX78706.1 - 0.12 11.8 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KXX78707.1 - 7e-97 324.0 0.0 8.7e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KXX78707.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KXX78708.1 - 1.7e-57 193.2 0.0 2.1e-43 147.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KXX78708.1 - 3.5e-29 100.6 0.0 8.4e-29 99.4 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KXX78708.1 - 1.7e-08 34.6 14.3 9.6e-05 22.4 0.2 5.4 4 2 1 5 5 5 2 AAA ATPase domain AAA_2 PF07724.9 KXX78708.1 - 2.7e-07 30.6 0.0 0.0063 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KXX78708.1 - 3e-07 30.2 0.6 0.0007 19.2 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 KXX78708.1 - 9.3e-06 25.3 0.0 0.035 13.8 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KXX78708.1 - 1.5e-05 24.8 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KXX78708.1 - 3.4e-05 23.9 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KXX78708.1 - 4.3e-05 23.0 0.7 0.091 12.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 KXX78708.1 - 4.4e-05 23.3 0.1 0.39 10.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX78708.1 - 7e-05 22.9 5.1 0.19 11.8 0.1 4.3 3 2 0 3 3 2 2 AAA domain RuvB_N PF05496.7 KXX78708.1 - 0.00019 20.5 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX78708.1 - 0.00021 21.0 0.1 1.1 9.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KXX78708.1 - 0.0003 19.7 0.1 0.073 11.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 KXX78708.1 - 0.00031 19.8 0.6 0.9 8.6 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.1 KXX78708.1 - 0.001 19.3 0.5 1.8 8.9 0.0 3.5 3 1 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 KXX78708.1 - 0.0011 18.4 0.0 0.07 12.5 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KXX78708.1 - 0.0011 18.1 0.2 0.69 9.0 0.0 2.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KXX78708.1 - 0.0016 18.6 0.0 4.3 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase KaiC PF06745.8 KXX78708.1 - 0.0028 16.8 0.1 0.66 9.0 0.0 2.4 2 0 0 2 2 2 1 KaiC TIP49 PF06068.8 KXX78708.1 - 0.0028 16.4 0.0 0.9 8.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus NTPase_1 PF03266.10 KXX78708.1 - 0.01 15.5 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 NTPase CobU PF02283.11 KXX78708.1 - 0.011 15.2 1.2 0.1 11.9 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_28 PF13521.1 KXX78708.1 - 0.011 15.7 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KXX78708.1 - 0.013 14.7 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 KXX78708.1 - 0.016 14.1 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KXX78708.1 - 0.02 14.4 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KXX78708.1 - 0.025 13.4 0.1 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KXX78708.1 - 0.026 14.0 2.0 0.62 9.6 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KXX78708.1 - 0.037 13.5 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KXX78708.1 - 0.041 12.8 0.1 1.5 7.6 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.22 KXX78708.1 - 0.064 13.5 0.0 22 5.3 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 KXX78708.1 - 0.12 12.0 0.0 25 4.4 0.0 3.3 2 1 1 3 3 3 0 Archaeal ATPase AAA_17 PF13207.1 KXX78708.1 - 0.12 13.1 10.6 0.16 12.8 0.0 3.9 4 1 0 4 4 2 0 AAA domain MobB PF03205.9 KXX78708.1 - 0.13 11.9 0.5 0.45 10.2 0.0 2.2 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 KXX78708.1 - 0.2 11.3 1.2 0.91 9.1 0.0 2.6 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_25 PF13481.1 KXX78708.1 - 0.35 10.2 11.0 1.7 7.9 0.2 4.5 3 2 1 5 5 4 0 AAA domain AAA_24 PF13479.1 KXX78708.1 - 0.35 10.4 1.1 6.9 6.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain RhoGAP PF00620.22 KXX78709.1 - 1.3e-28 99.5 0.0 2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 KXX78710.1 - 4.4e-57 192.1 1.6 5.2e-57 191.9 1.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) FAD_binding_3 PF01494.14 KXX78712.1 - 1.3e-21 77.0 0.0 3.7e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX78712.1 - 6.3e-05 22.0 0.0 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX78712.1 - 0.00033 19.6 0.7 0.0042 16.0 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KXX78712.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 KXX78712.1 - 0.0094 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KXX78712.1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX78712.1 - 0.055 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KXX78712.1 - 0.096 11.2 0.0 2.9 6.4 0.0 2.7 2 1 1 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 KXX78712.1 - 0.18 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Complex1_49kDa PF00346.14 KXX78713.1 - 2.5e-133 443.2 0.0 3.3e-133 442.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 KXX78714.1 - 4e-27 94.5 0.0 7.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KXX78714.1 - 1e-10 40.5 0.0 1.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 KXX78715.1 - 8.1e-39 132.5 0.8 1.3e-38 131.9 0.2 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KXX78715.1 - 3.5e-32 110.0 0.0 6.6e-32 109.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KXX78715.1 - 9e-25 86.0 0.2 1.6e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KXX78715.1 - 8.2e-16 57.1 1.9 2e-15 55.8 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KXX78715.1 - 5e-05 23.3 0.0 0.00065 19.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 KXX78715.1 - 0.00015 21.9 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KXX78715.1 - 0.0096 16.1 0.3 0.022 15.0 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Ecm33 PF12454.3 KXX78715.1 - 0.029 14.2 3.2 0.063 13.1 2.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein MoeZ_MoeB PF05237.8 KXX78715.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain DAO PF01266.19 KXX78715.1 - 0.064 12.1 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Telomere_reg-2 PF10193.4 KXX78716.1 - 2.5e-40 137.2 0.0 6.3e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein COX17 PF05051.8 KXX78717.1 - 6.1e-20 70.9 6.5 7.2e-20 70.7 4.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_60s PF00428.14 KXX78717.1 - 0.12 12.8 1.0 0.15 12.4 0.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cmc1 PF08583.5 KXX78717.1 - 0.14 11.9 4.1 0.67 9.7 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like G-patch PF01585.18 KXX78719.1 - 3.3e-06 26.7 0.0 2e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KXX78719.1 - 0.00058 19.6 0.2 0.00058 19.6 0.2 3.9 4 1 0 4 4 4 1 DExH-box splicing factor binding site CDC27 PF09507.5 KXX78719.1 - 0.025 13.8 38.9 0.034 13.3 27.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 KXX78719.1 - 1.6 7.0 44.0 2.7 6.3 30.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 KXX78722.1 - 1.3e-55 188.4 0.0 1.8e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78722.1 - 6e-41 140.2 0.0 1.2e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ECH PF00378.15 KXX78722.1 - 0.0047 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Kinase-like PF14531.1 KXX78722.1 - 0.015 14.2 0.0 0.047 12.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KXX78722.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX78722.1 - 0.098 12.3 0.0 0.57 9.8 0.0 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family MCM PF00493.18 KXX78723.1 - 2.2e-140 467.1 0.0 2.9e-140 466.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KXX78723.1 - 1.6e-19 70.6 0.0 6e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX78723.1 - 1.4e-05 24.3 0.0 0.00035 19.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX78723.1 - 1.5e-05 24.7 0.1 6.9e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KXX78723.1 - 0.0044 16.6 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KXX78723.1 - 0.027 13.1 0.4 0.045 12.4 0.3 1.2 1 0 0 1 1 1 0 AAA domain Zn-ribbon_8 PF09723.5 KXX78723.1 - 0.089 12.7 0.7 0.18 11.7 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 KXX78723.1 - 0.25 10.7 1.6 0.28 10.6 0.1 1.8 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Pil1 PF13805.1 KXX78724.1 - 2.5e-101 338.3 2.5 3.3e-101 338.0 1.7 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3678 PF12435.3 KXX78724.1 - 1 8.9 9.3 2.2 7.8 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Sua5_yciO_yrdC PF01300.13 KXX78725.1 - 2.7e-49 166.8 0.0 5.3e-49 165.8 0.0 1.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KXX78725.1 - 2.7e-25 88.8 0.0 4.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.15 KXX78726.1 - 1.1e-14 54.3 0.3 1.6e-13 50.6 0.2 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain VTC PF09359.5 KXX78727.1 - 3.4e-101 337.9 0.0 5.7e-101 337.2 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KXX78727.1 - 1.7e-27 96.8 0.0 2.5e-13 50.4 0.0 2.5 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 KXX78727.1 - 4.5e-12 46.0 3.2 1.1e-11 44.8 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 KXX78727.1 - 0.0003 20.4 0.2 0.029 14.0 0.1 2.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 KXX78727.1 - 0.023 14.8 0.1 0.22 11.6 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn helix Fe_dep_repress PF01325.14 KXX78727.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2910 PF11139.3 KXX78727.1 - 0.085 11.9 1.0 0.13 11.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Ank_2 PF12796.2 KXX78728.1 - 3.8e-06 27.1 0.0 2.2e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX78728.1 - 0.02 15.1 0.2 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ribophorin_I PF04597.9 KXX78729.1 - 1.6e-154 514.6 0.0 1.8e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.11 KXX78730.1 - 6.9e-85 284.1 0.0 9.8e-85 283.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KXX78730.1 - 2.6e-76 255.5 0.0 1.8e-75 252.8 0.0 1.9 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 KXX78730.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MiAMP1 PF09117.5 KXX78730.1 - 0.19 12.1 0.1 0.19 12.1 0.1 1.6 2 0 0 2 2 2 0 MiAMP1 RmlD_sub_bind PF04321.12 KXX78731.1 - 1.8e-56 191.1 0.0 2.4e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KXX78731.1 - 1.5e-24 86.7 0.0 7.2e-24 84.5 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX78731.1 - 2.3e-13 49.6 0.1 3.5e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KXX78731.1 - 6.1e-11 41.5 0.1 1.4e-10 40.3 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KXX78731.1 - 6.4e-07 28.5 0.9 0.00041 19.3 0.6 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KXX78731.1 - 6.7e-07 29.4 1.2 1.4e-06 28.4 0.8 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX78731.1 - 0.00029 20.1 0.6 0.015 14.5 0.3 2.5 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KXX78731.1 - 0.00052 19.9 1.9 0.0054 16.6 1.3 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX78731.1 - 0.47 10.0 4.6 1.5 8.4 0.2 2.5 2 1 1 3 3 3 0 KR domain 6PF2K PF01591.13 KXX78732.1 - 1.3e-58 197.7 0.0 1.8e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KXX78732.1 - 1.1e-23 84.0 0.4 1.9e-23 83.2 0.3 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KXX78732.1 - 5.8e-05 22.9 0.0 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX78732.1 - 0.0046 17.7 1.1 0.071 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF4302 PF14135.1 KXX78733.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) PH PF00169.24 KXX78733.1 - 0.12 12.5 0.4 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 PH domain Acyl-CoA_dh_1 PF00441.19 KXX78735.1 - 1.5e-20 73.8 0.1 2.8e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX78735.1 - 2.9e-17 61.9 0.0 6.3e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KXX78735.1 - 1.2e-12 48.1 0.8 2.5e-11 43.9 0.1 2.2 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX78735.1 - 5.9e-12 46.1 0.1 1.1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 KXX78736.1 - 7.6e-16 57.4 0.6 1.5e-15 56.4 0.4 1.5 1 0 0 1 1 1 1 Spo12 family Porin_3 PF01459.17 KXX78737.1 - 9.1e-80 267.8 0.4 1.1e-79 267.6 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin UCH_1 PF13423.1 KXX78738.1 - 6.6e-81 271.9 0.0 1.3e-80 271.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KXX78738.1 - 9.4e-17 61.0 0.0 4.5e-16 58.7 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Mt_ATP-synt_B PF05405.9 KXX78738.1 - 0.11 11.9 1.4 0.88 9.0 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TGS PF02824.16 KXX78739.1 - 9.2e-21 73.4 0.1 1.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KXX78739.1 - 1.8e-19 69.7 0.0 5.7e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX78739.1 - 1.2e-12 47.4 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KXX78739.1 - 2.9e-05 23.9 0.3 0.027 14.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KXX78739.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KXX78739.1 - 0.047 12.4 0.3 0.11 11.2 0.1 1.7 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 KXX78739.1 - 0.061 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family RRM_1 PF00076.17 KXX78740.1 - 2.9e-09 36.4 0.0 5.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX78740.1 - 2.5e-07 30.4 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX78740.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KXX78740.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KXX78740.1 - 0.015 14.9 0.7 0.031 13.9 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sulfate_transp PF00916.15 KXX78741.1 - 1.1e-71 241.0 10.1 2e-71 240.2 7.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX78741.1 - 3.9e-29 100.1 3.9 3.9e-29 100.1 2.7 3.3 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KXX78741.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-UBR PF02207.15 KXX78742.1 - 1.7e-18 66.1 15.9 3.8e-18 64.9 11.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KXX78742.1 - 0.00019 21.0 0.0 0.0006 19.4 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.14 KXX78742.1 - 1.2 8.3 3.5 2.2 7.5 2.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.7 KXX78743.1 - 4.1e-26 90.3 1.7 4.9e-26 90.1 1.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like WavE PF07507.6 KXX78743.1 - 0.097 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Mago-bind PF09282.5 KXX78744.1 - 3e-15 55.4 3.4 6.2e-15 54.4 2.4 1.6 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 KXX78744.1 - 0.15 11.9 16.2 0.19 11.6 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4612 PF15389.1 KXX78744.1 - 0.3 11.6 8.9 0.55 10.8 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) DUF2201_N PF13203.1 KXX78744.1 - 0.8 8.8 10.5 1.1 8.3 7.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Borrelia_P83 PF05262.6 KXX78744.1 - 1.8 6.7 13.6 1.8 6.7 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.5 KXX78744.1 - 2.6 8.0 15.6 4 7.4 10.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 KXX78744.1 - 3.5 7.3 5.9 4.1 7.1 4.1 1.3 1 0 0 1 1 1 0 DDHD domain MRL1 PF13003.2 KXX78744.1 - 4 7.2 7.8 2.5 7.8 3.8 1.8 1 1 1 2 2 2 0 Ribosomal protein L1 Spore_coat_CotO PF14153.1 KXX78744.1 - 4 6.8 14.5 5.7 6.3 10.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.12 KXX78744.1 - 4.3 6.0 4.5 4.5 5.9 3.1 1.1 1 0 0 1 1 1 0 Presenilin RNase_H2-Ydr279 PF09468.5 KXX78744.1 - 6.6 5.8 10.8 8.8 5.4 7.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ycf1 PF05758.7 KXX78744.1 - 8.7 3.9 9.0 10 3.7 6.2 1.0 1 0 0 1 1 1 0 Ycf1 Tom37_C PF11801.3 KXX78744.1 - 9 6.1 7.3 14 5.4 5.1 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1510 PF07423.6 KXX78744.1 - 9.1 5.5 15.7 14 4.9 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_S11 PF00411.14 KXX78745.1 - 3e-11 43.4 0.2 5.1e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4160 PF13711.1 KXX78745.1 - 0.28 11.0 1.9 0.81 9.5 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4160) Tim44 PF04280.10 KXX78746.1 - 8e-33 113.4 0.0 8e-33 113.4 0.0 2.3 2 0 0 2 2 2 1 Tim44-like domain CDC45 PF02724.9 KXX78746.1 - 0.16 9.9 13.8 0.21 9.5 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 KXX78746.1 - 0.71 9.2 20.3 0.67 9.3 9.7 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 DUF913 PF06025.7 KXX78746.1 - 8.8 4.9 6.6 17 3.9 4.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1768 PF08719.6 KXX78747.1 - 3.8e-38 130.6 0.2 2.2e-36 124.9 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) BCS1_N PF08740.6 KXX78748.1 - 3.1e-44 150.8 0.0 4.5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KXX78748.1 - 1.1e-20 74.1 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX78748.1 - 1.7e-05 23.9 0.0 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KXX78748.1 - 2.2e-05 24.5 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX78748.1 - 4.7e-05 24.2 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX78748.1 - 9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KXX78748.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KXX78748.1 - 0.00045 19.6 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KXX78748.1 - 0.0022 17.8 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX78748.1 - 0.0022 17.7 0.2 0.018 14.7 0.1 2.6 1 1 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KXX78748.1 - 0.0033 16.3 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX78748.1 - 0.011 15.2 0.4 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KXX78748.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KXX78748.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX78748.1 - 0.032 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX78748.1 - 0.034 14.4 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KXX78748.1 - 0.047 12.7 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KXX78748.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.1 KXX78748.1 - 0.049 13.5 0.1 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KXX78748.1 - 0.049 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 KXX78748.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 KXX78748.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KXX78748.1 - 0.09 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KXX78748.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 KXX78748.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KXX78748.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KXX78748.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TIP49 PF06068.8 KXX78748.1 - 0.21 10.2 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus polyprenyl_synt PF00348.12 KXX78749.1 - 1.2e-71 240.6 0.0 1.4e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 KXX78750.1 - 3e-48 163.1 0.0 8.3e-48 161.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KXX78750.1 - 1.2e-17 62.7 9.5 0.00034 20.0 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX78750.1 - 6.8e-15 54.4 23.3 8.8e-08 31.6 1.1 7.5 6 2 2 8 8 8 3 TPR repeat TPR_8 PF13181.1 KXX78750.1 - 9.9e-15 53.1 6.7 0.00025 20.6 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78750.1 - 3.3e-10 39.0 29.4 0.22 11.4 0.0 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX78750.1 - 1.3e-08 34.6 23.5 8.2e-05 22.4 0.7 6.9 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX78750.1 - 1.4e-08 34.5 14.2 0.004 17.6 0.1 9.0 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78750.1 - 1.7e-05 25.3 0.9 1.7e-05 25.3 0.6 7.3 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX78750.1 - 0.00022 21.1 2.5 1.4 9.3 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX78750.1 - 0.00024 20.6 12.4 0.1 12.4 0.0 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX78750.1 - 0.00041 20.4 11.8 0.6 10.2 0.1 5.5 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX78750.1 - 0.00085 19.1 14.8 0.048 13.5 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF4398 PF14346.1 KXX78750.1 - 0.003 17.6 0.4 0.003 17.6 0.3 1.9 2 0 0 2 2 1 1 Domain of unknown function (DUF4398) TPR_6 PF13174.1 KXX78750.1 - 0.006 16.9 15.9 1.3 9.5 0.3 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat ChAPs PF09295.5 KXX78750.1 - 0.016 13.9 0.1 2.1 7.0 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 KXX78750.1 - 0.019 14.7 3.5 0.11 12.2 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KXX78750.1 - 0.13 12.6 17.3 3.2 8.1 0.0 6.2 7 1 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 KXX78750.1 - 0.63 9.9 6.2 0.76 9.6 0.0 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Vps54 PF07928.7 KXX78752.1 - 1.1e-46 158.3 0.1 2.5e-46 157.1 0.1 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KXX78752.1 - 9e-07 28.0 0.2 2.8e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KXX78752.1 - 0.0031 17.1 0.6 0.2 11.2 0.1 3.0 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 KXX78752.1 - 0.033 14.0 0.6 0.22 11.3 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PACT_coil_coil PF10495.4 KXX78752.1 - 0.061 13.2 0.1 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein LUC7 PF03194.10 KXX78752.1 - 0.14 11.6 0.9 0.35 10.3 0.6 1.6 1 0 0 1 1 1 0 LUC7 N_terminus zf-C4H2 PF10146.4 KXX78752.1 - 0.28 11.1 0.9 3.9 7.4 0.1 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein SbmA_BacA PF05992.7 KXX78752.1 - 0.3 10.2 0.0 0.55 9.3 0.0 1.3 1 0 0 1 1 1 0 SbmA/BacA-like family DUF904 PF06005.7 KXX78752.1 - 3.8 7.8 8.2 1.2 9.4 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF904) MCM PF00493.18 KXX78753.1 - 9.2e-142 471.7 0.1 1.2e-141 471.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KXX78753.1 - 4.4e-17 62.6 0.3 1.1e-16 61.3 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX78753.1 - 7.3e-07 28.5 0.0 0.00021 20.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX78753.1 - 1.2e-05 25.0 0.0 4.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KXX78753.1 - 0.0003 20.3 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KXX78753.1 - 0.026 14.9 1.4 0.062 13.7 0.3 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KXX78753.1 - 0.046 13.1 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Lon_2 PF13337.1 KXX78753.1 - 0.11 10.7 0.2 1.1 7.5 0.0 2.0 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease HGTP_anticodon2 PF12745.2 KXX78754.1 - 1.1e-83 280.5 1.6 6.3e-83 278.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KXX78754.1 - 2.6e-75 252.9 0.0 6.1e-38 130.4 0.0 4.2 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78754.1 - 2e-47 161.4 0.0 3.9e-21 75.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 KXX78754.1 - 2.5e-17 62.9 2.4 7.9e-17 61.2 0.0 2.5 2 1 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 KXX78754.1 - 9.9e-12 44.7 0.1 3e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 KXX78754.1 - 1.2e-05 24.4 0.0 5.4e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KXX78754.1 - 1.6e-05 24.7 0.9 0.03 14.0 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family DUF4208 PF13907.1 KXX78754.1 - 0.82 9.9 9.4 0.65 10.2 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) AAA_23 PF13476.1 KXX78754.1 - 1.6 9.0 6.9 5.1 7.3 4.8 1.8 1 0 0 1 1 1 0 AAA domain Cut12 PF11500.3 KXX78755.1 - 4.5e-43 146.5 12.6 4.5e-43 146.5 8.7 4.9 5 2 2 7 7 7 1 Spindle pole body formation-associated protein UreF PF01730.11 KXX78755.1 - 3.6e-12 46.6 2.1 4.9e-12 46.1 0.1 2.3 2 0 0 2 2 2 1 UreF UBA_4 PF14555.1 KXX78756.1 - 0.027 14.0 0.2 0.08 12.4 0.1 1.9 1 0 0 1 1 1 0 UBA-like domain UIM PF02809.15 KXX78756.1 - 6.6 6.5 10.6 1.2 8.8 3.5 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif UQ_con PF00179.21 KXX78757.1 - 1.1e-35 122.1 0.0 1.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX78757.1 - 0.058 13.1 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B DUF410 PF04190.8 KXX78759.1 - 1.3e-45 155.9 0.0 1.6e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) GMC_oxred_C PF05199.8 KXX78760.1 - 2.9e-10 40.6 0.2 1.2e-08 35.3 0.1 2.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KXX78760.1 - 7e-07 28.6 0.3 5e-06 25.8 0.2 2.1 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX78760.1 - 3.6e-05 22.8 0.6 0.021 13.7 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX78760.1 - 7.1e-05 21.8 0.3 0.00011 21.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KXX78760.1 - 0.0013 17.9 0.1 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX78760.1 - 0.0068 16.3 0.5 0.02 14.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX78760.1 - 0.016 15.0 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX78760.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX78760.1 - 0.079 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KXX78760.1 - 0.085 11.3 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KXX78760.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF900 PF05990.7 KXX78760.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thi4 PF01946.12 KXX78760.1 - 0.19 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DNA_pol_B PF00136.16 KXX78761.1 - 5.3e-146 487.0 2.9 7.5e-146 486.5 2.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KXX78761.1 - 5.4e-81 271.9 0.5 1.2e-80 270.8 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KXX78761.1 - 4.7e-21 74.5 3.5 4.7e-21 74.5 2.4 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 KXX78761.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KXX78761.1 - 0.00046 20.0 0.2 0.0025 17.6 0.1 2.4 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 KXX78761.1 - 0.9 9.3 9.5 0.37 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RabGAP-TBC PF00566.13 KXX78762.1 - 5.2e-33 114.3 0.0 4.5e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.15 KXX78763.1 - 7.1e-59 198.8 19.7 8.8e-59 198.5 13.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Tex_N PF09371.5 KXX78763.1 - 0.12 11.6 0.5 0.24 10.7 0.3 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain An_peroxidase PF03098.10 KXX78763.1 - 0.18 10.1 0.1 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase DUF2305 PF10230.4 KXX78764.1 - 4.1e-51 173.9 0.0 5.5e-49 166.9 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KXX78764.1 - 8.9e-08 32.2 0.2 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX78764.1 - 0.0019 17.9 0.0 0.004 16.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX78764.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KXX78764.1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FHA PF00498.21 KXX78764.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 FHA domain Abhydrolase_1 PF00561.15 KXX78764.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ABC2_membrane_4 PF12730.2 KXX78765.1 - 1.9 7.6 10.0 4.2 6.4 0.2 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Spherulin4 PF12138.3 KXX78766.1 - 9.3e-11 41.6 0.0 3e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Spherulation-specific family 4 CVNH PF08881.5 KXX78767.1 - 6.4e-13 48.8 0.1 1.3e-11 44.5 0.1 2.1 1 1 0 1 1 1 1 CVNH domain EGF_3 PF12947.2 KXX78767.1 - 4.5 7.3 9.3 15 5.6 0.2 3.2 3 1 0 3 3 3 0 EGF domain DUF1282 PF06930.7 KXX78769.1 - 0.028 14.0 0.3 0.045 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) MUG113 PF13455.1 KXX78771.1 - 1.8e-32 111.6 0.7 3.1e-32 110.8 0.5 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KXX78771.1 - 3.2e-23 82.0 1.1 8.9e-23 80.5 0.7 1.8 2 0 0 2 2 2 1 T5orf172 domain zf-primase PF09329.6 KXX78771.1 - 0.032 13.8 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 Primase zinc finger Ribonuclease PF00545.15 KXX78772.1 - 2e-16 59.7 0.1 2.8e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 ribonuclease FG-GAP PF01839.18 KXX78772.1 - 0.028 14.1 0.5 0.06 13.0 0.4 1.6 1 0 0 1 1 1 0 FG-GAP repeat Swi5 PF07061.6 KXX78773.1 - 9.4e-22 76.5 0.1 2e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Swi5 DUF4051 PF13260.1 KXX78773.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) DCP1 PF06058.8 KXX78774.1 - 3e-15 56.3 0.0 1.4e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family Abhydrolase_3 PF07859.8 KXX78775.1 - 3e-18 66.1 0.0 4.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX78775.1 - 2.3e-06 26.5 0.0 5.8e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KXX78775.1 - 0.0059 15.8 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX78775.1 - 0.049 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 KXX78776.1 - 2.9e-70 237.1 18.8 3.3e-70 236.9 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX78776.1 - 3.8e-16 58.7 31.3 3.8e-16 58.7 21.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KXX78777.1 - 2.8e-24 86.2 0.0 1.1e-23 84.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KXX78777.1 - 1.8e-05 23.1 0.0 3.6e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KXX78777.1 - 0.00014 21.7 0.0 0.00078 19.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KXX78777.1 - 0.0011 19.0 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KXX78777.1 - 0.0093 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KXX78777.1 - 0.024 14.4 0.1 0.59 9.8 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Cyclase PF04199.8 KXX78778.1 - 2.1e-15 56.8 0.2 3e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Tachylectin PF14517.1 KXX78778.1 - 0.11 11.8 0.3 7 5.9 0.1 2.8 2 1 1 3 3 3 0 Tachylectin NACHT PF05729.7 KXX78780.1 - 1.3e-18 67.2 0.0 2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX78780.1 - 0.0052 16.7 0.2 0.023 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX78780.1 - 0.017 15.2 0.1 0.062 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 KXX78780.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.4 KXX78780.1 - 0.055 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KXX78780.1 - 0.056 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KXX78781.1 - 0.0088 13.4 40.6 0.012 12.9 28.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HOOK PF05622.7 KXX78781.1 - 0.039 11.7 41.4 0.059 11.1 28.7 1.2 1 0 0 1 1 1 0 HOOK protein Macoilin PF09726.4 KXX78781.1 - 3.2 5.9 32.0 4.7 5.3 22.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4250 PF14056.1 KXX78781.1 - 3.4 7.4 18.1 0.57 9.9 0.5 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4250) V_ATPase_I PF01496.14 KXX78781.1 - 7.5 4.2 21.0 11 3.7 14.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.1 KXX78781.1 - 9.3 5.6 54.8 0.19 11.1 18.2 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Pectate_lyase_3 PF12708.2 KXX78784.1 - 3.8e-67 226.6 18.6 9.5e-53 179.6 5.4 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KXX78784.1 - 0.0022 17.4 2.4 0.015 14.7 0.2 2.6 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Varsurf_PPLC PF03490.8 KXX78784.1 - 0.0038 16.8 0.1 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C 4HBT PF03061.17 KXX78785.1 - 1.6e-14 53.8 0.8 2.7e-14 53.0 0.5 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.14 KXX78786.1 - 1.6e-23 83.0 0.3 2.5e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KXX78786.1 - 3.6e-15 56.2 7.3 1.2e-13 51.4 1.9 3.2 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KXX78786.1 - 3.5e-09 36.3 0.0 6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KXX78786.1 - 0.0016 18.5 0.4 0.0046 17.1 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.21 KXX78787.1 - 2.2e-38 130.8 0.0 2.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KXX78787.1 - 2.7e-06 26.8 0.1 4.5e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KXX78787.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KXX78787.1 - 0.05 13.2 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 UEV domain Sod_Fe_C PF02777.13 KXX78788.1 - 7e-34 115.8 0.0 1.3e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KXX78788.1 - 7.3e-34 115.8 4.7 7.3e-34 115.8 3.3 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain BAG PF02179.11 KXX78790.1 - 1e-19 70.4 0.3 1.7e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KXX78790.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Glutaredoxin PF00462.19 KXX78791.1 - 3.3e-19 68.6 0.0 7.3e-19 67.5 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin TraF PF13728.1 KXX78791.1 - 0.00059 19.3 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KXX78791.1 - 0.0023 17.5 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX78791.1 - 0.0055 16.8 0.1 0.0075 16.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KXX78791.1 - 0.029 14.3 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.1 KXX78791.1 - 0.03 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4124 PF13511.1 KXX78791.1 - 0.059 13.4 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DUF953 PF06110.6 KXX78791.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.9 KXX78791.1 - 0.075 13.2 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 KXX78791.1 - 0.14 11.6 0.3 0.4 10.2 0.1 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AAA PF00004.24 KXX78792.1 - 3.2e-41 140.6 0.0 6.2e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX78792.1 - 5.3e-07 29.8 0.1 0.00019 21.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KXX78792.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KXX78792.1 - 1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KXX78792.1 - 3.8e-05 23.4 0.1 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX78792.1 - 0.00018 21.5 0.1 0.001 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KXX78792.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KXX78792.1 - 0.00093 19.1 0.3 0.004 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KXX78792.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX78792.1 - 0.0037 16.9 0.2 0.35 10.5 0.0 2.7 2 1 1 3 3 3 1 NACHT domain AAA_33 PF13671.1 KXX78792.1 - 0.0055 16.5 0.1 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX78792.1 - 0.006 17.3 0.9 0.011 16.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KXX78792.1 - 0.0063 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KXX78792.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KXX78792.1 - 0.009 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KXX78792.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KXX78792.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KXX78792.1 - 0.015 14.5 1.9 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 KXX78792.1 - 0.019 13.6 0.1 0.045 12.4 0.1 1.6 1 1 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KXX78792.1 - 0.04 12.7 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 KXX78792.1 - 0.041 12.9 0.2 0.43 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 KXX78792.1 - 0.045 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KXX78792.1 - 0.052 13.1 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX78792.1 - 0.054 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KXX78792.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KXX78792.1 - 0.17 11.2 5.5 0.26 10.6 0.3 2.7 2 1 0 3 3 3 0 AAA domain Ribosomal_L13 PF00572.13 KXX78793.1 - 4.9e-28 97.7 0.0 9.8e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Chalcone PF02431.10 KXX78794.1 - 3.6e-61 206.0 0.0 4.8e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase F-box-like PF12937.2 KXX78795.1 - 3e-12 46.0 4.7 5.6e-12 45.1 0.7 2.6 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 KXX78795.1 - 1.8e-10 39.7 16.6 1.1 9.5 0.0 11.6 13 0 0 13 13 13 2 Leucine Rich repeat LRR_4 PF12799.2 KXX78795.1 - 7e-09 35.1 8.9 0.21 11.2 0.0 7.0 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KXX78795.1 - 0.00035 20.1 0.6 0.00035 20.1 0.4 2.3 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KXX78795.1 - 0.0019 17.9 26.3 0.97 9.7 0.0 9.7 7 4 1 8 8 8 1 Leucine Rich Repeat Recep_L_domain PF01030.19 KXX78795.1 - 0.012 15.5 1.1 34 4.4 0.0 4.1 2 1 2 4 4 4 0 Receptor L domain LRR_7 PF13504.1 KXX78795.1 - 4.1 8.0 27.6 30 5.4 0.0 9.6 10 1 0 10 10 10 0 Leucine rich repeat PAN_4 PF14295.1 KXX78796.1 - 0.014 15.0 0.0 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 PAN domain Acetyltransf_1 PF00583.19 KXX78797.1 - 3.1e-07 30.3 0.3 5.2e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX78797.1 - 0.00014 21.9 0.1 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX78797.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 KXX78797.1 - 0.058 13.5 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX78797.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2217 PF10265.4 KXX78798.1 - 0.14 10.9 0.8 0.31 9.7 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Glyco_hydro_3 PF00933.16 KXX78799.1 - 3.7e-83 278.9 0.0 5.2e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX78799.1 - 8.2e-44 149.8 0.0 5.9e-43 146.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX78799.1 - 1.3e-20 73.0 0.1 2.5e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pex24p PF06398.6 KXX78800.1 - 4.5e-103 344.7 0.0 5.5e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ank_2 PF12796.2 KXX78801.1 - 2.9e-91 299.9 0.0 7.5e-22 77.4 0.0 4.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX78801.1 - 1.4e-64 213.4 12.6 2e-11 44.0 0.0 7.8 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 KXX78801.1 - 2.3e-49 162.8 0.1 9.9e-06 25.1 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KXX78801.1 - 3.6e-44 147.7 4.9 3.4e-09 36.6 0.0 7.1 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78801.1 - 1.6e-43 142.3 0.0 0.00011 22.0 0.0 8.2 7 0 0 7 7 7 7 Ankyrin repeat NACHT PF05729.7 KXX78801.1 - 5.5e-07 29.3 0.1 1.5e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX78801.1 - 6.2e-05 23.0 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX78801.1 - 0.00052 20.1 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 KXX78801.1 - 0.00063 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KXX78801.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_30 PF13604.1 KXX78801.1 - 0.0048 16.4 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KXX78801.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 KXX78801.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KXX78801.1 - 0.2 11.9 0.0 0.59 10.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Vint PF14623.1 KXX78807.1 - 4.3e-41 140.1 0.0 7.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KXX78807.1 - 5.7e-29 100.0 0.0 9.2e-29 99.3 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KXX78807.1 - 9.7e-17 61.6 0.0 1.7e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX78807.1 - 4e-15 55.9 0.0 5.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KXX78807.1 - 1.3e-11 44.3 0.0 4.2e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF3818 PF12825.2 KXX78810.1 - 1.2e-32 112.9 0.0 1.7e-20 73.0 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KXX78810.1 - 4.5e-32 110.5 0.0 9.7e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 PX-associated Cu-oxidase_3 PF07732.10 KXX78811.1 - 3.8e-28 97.5 0.0 4.4e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX78811.1 - 0.00072 19.0 0.3 0.0042 16.6 0.2 1.9 1 1 0 1 1 1 1 Multicopper oxidase MACPF PF01823.14 KXX78813.1 - 3.4e-07 30.1 1.6 5.1e-07 29.5 1.0 1.3 1 1 0 1 1 1 1 MAC/Perforin domain DUF1664 PF07889.7 KXX78814.1 - 0.012 15.4 1.9 0.024 14.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 KXX78814.1 - 0.037 13.1 4.2 0.11 11.5 2.9 1.8 1 1 0 1 1 1 0 Tropomyosin DUF445 PF04286.7 KXX78814.1 - 0.04 13.4 1.0 0.24 10.8 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) TBPIP PF07106.8 KXX78814.1 - 0.047 13.2 2.5 0.083 12.4 1.7 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 KXX78814.1 - 0.08 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.9 KXX78814.1 - 0.088 12.4 0.8 0.14 11.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3571 PF12095.3 KXX78814.1 - 0.089 13.0 0.5 0.37 11.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) Allexi_40kDa PF05549.6 KXX78814.1 - 0.15 11.3 1.1 0.22 10.8 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Thiolase_N PF00108.18 KXX78816.1 - 8.4e-73 244.5 1.7 1.2e-72 244.1 1.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX78816.1 - 1.8e-40 137.2 1.6 4.9e-40 135.7 1.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Phage_tube PF04985.9 KXX78816.1 - 0.056 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein FII DUF4239 PF14023.1 KXX78817.1 - 0.0084 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) PI-PLC-X PF00388.14 KXX78817.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF2317 PF10079.4 KXX78820.1 - 0.32 9.5 7.8 0.54 8.8 5.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF972 PF06156.8 KXX78820.1 - 2 8.8 5.5 0.58 10.5 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TIM21 PF08294.6 KXX78822.1 - 1.8e-46 157.3 0.1 2.3e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KXX78822.1 - 2.6e-07 30.1 0.0 5.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ADH_N PF08240.7 KXX78823.1 - 1.9e-29 101.5 0.3 1.9e-29 101.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX78823.1 - 7.7e-14 51.3 0.4 7.7e-14 51.3 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 KXX78824.1 - 7.2e-40 136.5 0.0 6.3e-27 94.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1847 PF08901.6 KXX78824.1 - 0.049 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) Cobl PF09469.5 KXX78824.1 - 0.096 12.6 0.6 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Lipase_3 PF01764.20 KXX78825.1 - 7.8e-15 54.7 0.0 1.5e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) DUF601 PF04642.7 KXX78825.1 - 2.8 7.2 8.7 4.6 6.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Acetyltransf_1 PF00583.19 KXX78826.1 - 2.2e-12 46.7 0.1 1.1e-11 44.6 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX78826.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX78826.1 - 0.085 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 KXX78827.1 - 9.5e-33 113.4 0.5 1.6e-32 112.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX78827.1 - 2.4e-24 86.4 0.0 3.4e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX78827.1 - 6.8e-16 58.4 0.6 1.2e-15 57.6 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX78827.1 - 4e-06 26.4 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX78827.1 - 0.00051 19.7 0.4 0.001 18.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KXX78827.1 - 0.0028 16.5 0.1 0.0053 15.6 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KXX78827.1 - 0.052 13.5 2.9 0.067 13.1 1.1 1.9 2 1 0 2 2 2 0 NADH(P)-binding PALP PF00291.20 KXX78827.1 - 0.054 12.7 0.1 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1815 PF08844.5 KXX78827.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NmrA PF05368.8 KXX78827.1 - 0.15 11.2 1.9 0.22 10.7 0.2 2.0 2 1 0 2 2 2 0 NmrA-like family DUF1100 PF06500.6 KXX78828.1 - 4.4e-12 45.2 0.0 5.6e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KXX78828.1 - 8e-10 38.6 0.0 1.9e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX78828.1 - 2.6e-09 37.2 0.1 6.4e-09 36.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX78828.1 - 2.7e-05 23.4 0.1 6.1e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KXX78828.1 - 0.00024 20.5 0.0 0.0024 17.3 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KXX78828.1 - 0.00034 20.1 0.2 0.00053 19.4 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 KXX78828.1 - 0.0025 17.1 0.0 0.007 15.6 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.13 KXX78828.1 - 0.0072 15.6 0.0 0.094 11.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family ArfGap PF01412.13 KXX78831.1 - 1.3e-34 118.4 0.7 5.5e-34 116.4 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.17 KXX78832.1 - 2.1e-62 210.2 0.0 3.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KXX78832.1 - 2.7e-39 133.8 0.0 8.3e-39 132.2 0.0 1.8 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.1 KXX78832.1 - 0.035 13.3 0.9 0.1 11.7 0.6 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase MGC-24 PF05283.6 KXX78835.1 - 5.5 6.7 10.7 9.8 5.9 7.4 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) NMO PF03060.10 KXX78836.1 - 7.1e-73 245.6 0.2 1e-72 245.0 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KXX78836.1 - 1.1e-08 34.3 0.0 2.7e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX78836.1 - 2.4e-06 26.6 1.3 3.5e-06 26.1 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KXX78836.1 - 0.0028 16.6 0.1 0.0052 15.7 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.9 KXX78836.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.16 KXX78836.1 - 0.069 12.1 0.1 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NDT80_PhoG PF05224.7 KXX78837.1 - 1.6e-43 148.8 0.0 3.5e-43 147.7 0.0 1.6 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Pur_DNA_glyco PF02245.11 KXX78837.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) MscL PF01741.13 KXX78838.1 - 8.1e-15 55.1 0.3 1.9e-14 53.8 0.2 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 KXX78838.1 - 0.00079 19.1 1.7 0.0013 18.4 1.2 1.4 1 0 0 1 1 1 1 BED zinc finger PBP1_TM PF14812.1 KXX78838.1 - 0.037 14.3 5.2 0.062 13.6 3.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stc1 PF12898.2 KXX78838.1 - 0.042 13.9 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 Stc1 domain C1_1 PF00130.17 KXX78838.1 - 0.076 12.7 1.6 0.12 12.1 1.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bd3614_N PF14442.1 KXX78838.1 - 3.5 7.5 6.6 7.1 6.6 4.6 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Cwf_Cwc_15 PF04889.7 KXX78838.1 - 6.6 6.3 6.2 9.3 5.8 4.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.7 KXX78839.1 - 1.7e-14 53.9 0.0 2.1e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family SNARE PF05739.14 KXX78840.1 - 2.2e-17 62.4 0.8 2.2e-17 62.4 0.6 3.2 4 0 0 4 4 3 1 SNARE domain Syntaxin PF00804.20 KXX78840.1 - 2.1e-13 50.3 0.3 2.1e-13 50.3 0.2 2.7 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KXX78840.1 - 0.0026 17.3 0.6 0.0026 17.3 0.4 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Peripla_BP_2 PF01497.13 KXX78840.1 - 0.012 14.7 0.2 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein DUF1664 PF07889.7 KXX78840.1 - 0.037 13.8 0.8 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KXX78840.1 - 0.06 11.9 5.2 0.046 12.3 0.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 KXX78840.1 - 0.063 13.4 1.7 1 9.5 0.1 2.8 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-18_N PF10496.4 KXX78840.1 - 0.07 12.9 0.3 0.4 10.5 0.1 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 KXX78840.1 - 0.14 12.4 3.2 20 5.5 0.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 KXX78840.1 - 0.67 8.8 4.7 3.3 6.5 0.2 2.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HisKA PF00512.20 KXX78840.1 - 2.2 8.3 4.9 23 5.0 0.1 3.4 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain PilJ PF13675.1 KXX78840.1 - 2.3 8.5 8.1 5.7 7.3 1.0 2.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glyco_hydro_43 PF04616.9 KXX78844.1 - 3.4e-29 101.8 3.1 1.4e-18 67.0 1.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Response_reg PF00072.19 KXX78845.1 - 2.4e-19 69.3 0.0 7.8e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain AAA_10 PF12846.2 KXX78846.1 - 6.2e-09 35.7 0.0 3.5e-05 23.3 0.0 2.3 2 1 0 2 2 2 2 AAA-like domain Zot PF05707.7 KXX78846.1 - 0.00091 18.7 0.0 0.0083 15.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 KXX78846.1 - 0.00099 19.1 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 KXX78846.1 - 0.0024 17.7 0.2 0.033 14.0 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KXX78846.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KXX78846.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KXX78846.1 - 0.12 12.5 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2052 PF09747.4 KXX78847.1 - 5e-34 117.7 0.7 6.3e-34 117.4 0.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.1 KXX78849.1 - 2.9e-43 147.9 0.0 4.4e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KXX78849.1 - 7.9e-16 57.9 0.0 1.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KXX78849.1 - 3.5e-05 23.2 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KXX78849.1 - 0.00037 19.8 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KXX78849.1 - 0.0091 15.5 0.0 0.034 13.7 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Bot1p PF12298.3 KXX78850.1 - 1.7e-54 184.3 4.1 2.8e-54 183.6 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Bromodomain PF00439.20 KXX78851.1 - 4.5e-20 71.3 0.1 7.9e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 KXX78851.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CHCH PF06747.8 KXX78851.1 - 0.26 11.2 1.7 9.6 6.2 0.7 2.3 2 0 0 2 2 2 0 CHCH domain Pectate_lyase_3 PF12708.2 KXX78852.1 - 5.6e-83 278.4 6.9 3.3e-67 226.8 0.8 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KXX78852.1 - 1.1e-06 27.9 2.2 0.03 13.7 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase HET PF06985.6 KXX78853.1 - 3.2e-26 92.1 0.0 6.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 KXX78853.1 - 0.011 15.2 14.1 0.011 15.2 9.8 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type CTD_bind PF04818.8 KXX78854.1 - 5e-21 74.6 0.1 1.2e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DGCR6 PF07324.6 KXX78854.1 - 0.0083 15.6 0.4 0.47 9.9 0.1 2.2 2 0 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein CTK3 PF12243.3 KXX78854.1 - 0.013 15.1 1.0 0.054 13.1 0.1 2.3 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 Reo_sigmaC PF04582.7 KXX78854.1 - 0.023 13.8 0.2 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 KXX78854.1 - 0.14 12.1 5.9 0.23 11.5 2.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil COG2 PF06148.6 KXX78854.1 - 0.88 9.4 3.1 2.5 7.9 2.1 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AA_kinase PF00696.23 KXX78855.1 - 1.3e-37 129.6 0.1 2.4e-37 128.8 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KXX78855.1 - 1.6e-15 56.2 1.9 3.3e-10 39.2 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KXX78855.1 - 2.1e-14 52.7 3.4 6.3e-11 41.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain SHNi-TPR PF10516.4 KXX78855.1 - 0.12 11.6 0.1 0.3 10.3 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR ABC_membrane PF00664.18 KXX78856.1 - 4.1e-47 160.9 10.6 5.3e-47 160.5 7.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KXX78856.1 - 5.6e-34 117.3 0.0 1.4e-33 116.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KXX78856.1 - 4.8e-06 25.9 0.0 0.00023 20.4 0.0 2.3 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KXX78856.1 - 8.3e-05 22.6 0.1 0.00023 21.2 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 KXX78856.1 - 0.00013 22.0 1.0 0.77 9.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KXX78856.1 - 0.0027 18.5 0.0 0.0058 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KXX78856.1 - 0.0035 16.8 0.0 0.0096 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX78856.1 - 0.0041 17.2 0.1 0.025 14.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KXX78856.1 - 0.0062 16.7 0.1 0.081 13.1 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX78856.1 - 0.019 14.7 0.1 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KXX78856.1 - 0.036 13.9 1.3 0.27 11.1 0.9 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 KXX78856.1 - 0.045 12.3 1.6 0.052 12.1 0.2 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Sigma54_activ_2 PF14532.1 KXX78856.1 - 0.069 13.1 0.0 0.71 9.9 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KXX78856.1 - 0.073 13.3 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX78856.1 - 0.11 11.8 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KXX78856.1 - 0.14 11.6 0.2 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KXX78856.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Spt4 PF06093.8 KXX78857.1 - 1.1e-32 111.6 0.1 1.4e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Kin17_mid PF10357.4 KXX78858.1 - 6.8e-47 158.2 3.6 1.4e-46 157.2 2.5 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KXX78858.1 - 0.00077 19.5 3.3 0.0015 18.5 2.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX78858.1 - 0.00079 19.5 3.4 0.0014 18.7 2.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KXX78858.1 - 0.0092 16.0 1.9 0.0092 16.0 1.3 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KXX78858.1 - 0.69 10.3 3.8 1.6 9.2 2.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger 7tm_2 PF00002.19 KXX78859.1 - 1.2e-12 47.4 3.8 1.2e-12 47.4 2.6 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KXX78859.1 - 2.2e-12 46.4 8.6 2.2e-12 46.4 6.0 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KXX78859.1 - 1.1e-07 31.6 9.9 1.1e-07 31.6 6.9 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KXX78859.1 - 6.8e-06 25.4 2.6 1.2e-05 24.6 1.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Vps39_2 PF10367.4 KXX78860.1 - 8.9e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KXX78860.1 - 0.0027 17.2 0.0 0.07 12.7 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS CASP_C PF08172.7 KXX78861.1 - 4.8e-91 304.2 0.0 4.8e-91 304.2 0.0 2.8 2 1 0 2 2 2 1 CASP C terminal ADIP PF11559.3 KXX78861.1 - 0.0062 16.4 6.0 0.0062 16.4 4.2 6.6 6 1 1 7 7 7 3 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 KXX78861.1 - 0.058 13.2 50.8 1.6 8.5 0.1 4.8 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) CVNH PF08881.5 KXX78861.1 - 2 8.6 7.8 18 5.6 0.3 3.4 2 1 1 3 3 3 0 CVNH domain DUF3584 PF12128.3 KXX78861.1 - 6.5 3.9 49.6 0.41 7.9 15.3 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3584) UPF0184 PF03670.8 KXX78861.1 - 7.7 6.7 10.5 0.72 10.0 0.1 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) NACHT PF05729.7 KXX78862.1 - 6.4e-07 29.1 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX78862.1 - 9.9e-06 25.6 0.6 8.4e-05 22.6 0.0 2.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 KXX78862.1 - 2.4e-05 24.4 0.0 9.6e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX78862.1 - 0.00071 20.3 0.1 0.0038 18.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KXX78862.1 - 0.00076 19.0 0.7 0.003 17.0 0.1 2.3 3 0 0 3 3 3 1 AAA-like domain AAA_19 PF13245.1 KXX78862.1 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KXX78862.1 - 0.012 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX78862.1 - 0.013 15.7 0.0 0.048 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KXX78862.1 - 0.022 13.6 0.0 0.071 11.9 0.0 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KXX78862.1 - 0.026 13.3 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KXX78862.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KXX78862.1 - 0.039 13.4 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KXX78862.1 - 0.044 13.3 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KXX78862.1 - 0.094 13.0 0.1 0.094 13.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 KXX78863.1 - 0.00018 21.6 19.6 0.95 9.9 0.5 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX78863.1 - 0.00041 20.4 16.3 0.13 12.6 0.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KXX78863.1 - 0.0068 16.2 1.3 0.069 13.0 0.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 KXX78863.1 - 0.085 11.3 0.1 0.43 9.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Fibrillarin PF01269.12 KXX78864.1 - 1.2e-106 354.7 0.0 1.5e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KXX78864.1 - 3.2e-06 26.8 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KXX78864.1 - 0.0039 16.7 0.1 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KXX78864.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22 PF00237.14 KXX78865.1 - 4e-34 116.7 0.0 5.8e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_C12 PF01088.16 KXX78866.1 - 3.4e-72 242.1 0.0 4.8e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-rbx1 PF12678.2 KXX78867.1 - 4.4e-12 45.9 1.5 7.8e-12 45.1 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KXX78867.1 - 1.7e-11 43.7 4.8 2.9e-11 43.0 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX78867.1 - 1.6e-07 30.8 3.5 3.9e-07 29.6 2.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX78867.1 - 5.5e-06 26.0 2.2 1.1e-05 25.0 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX78867.1 - 6.7e-06 25.6 3.5 1.1e-05 24.9 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX78867.1 - 9.2e-06 25.5 3.1 2.9e-05 23.9 2.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX78867.1 - 0.00033 20.4 0.5 0.00068 19.4 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KXX78867.1 - 0.0029 17.2 2.4 0.0081 15.8 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KXX78867.1 - 0.0073 15.8 0.3 0.015 14.8 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KXX78867.1 - 0.53 9.9 2.7 1.2 8.7 1.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KXX78867.1 - 2 8.4 4.9 1.9 8.4 1.9 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain Methyltransf_16 PF10294.4 KXX78868.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF3455 PF11937.3 KXX78870.1 - 1.7e-43 148.6 0.1 2.2e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KXX78870.1 - 0.055 13.3 1.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Pkinase PF00069.20 KXX78871.1 - 1.4e-08 34.1 0.0 4.3e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Ribosomal_S9 PF00380.14 KXX78873.1 - 7.9e-36 122.9 0.8 1.2e-35 122.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 KXX78874.1 - 1e-42 144.1 0.1 1.7e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KXX78874.1 - 4.2e-15 55.4 0.0 1.5e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX78874.1 - 5e-12 45.8 0.0 2.1e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX78874.1 - 3e-11 43.0 0.0 1.3e-10 41.0 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX78874.1 - 1.7e-09 37.7 0.5 3.6e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX78874.1 - 3.8e-08 33.7 0.0 8.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KXX78874.1 - 0.00068 19.5 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 KXX78875.1 - 4e-15 55.8 0.0 5.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AMPKBI PF04739.10 KXX78876.1 - 8.1e-23 80.1 1.0 8.1e-23 80.1 0.7 1.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 KXX78877.1 - 5.8e-84 281.7 0.1 6.8e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KXX78877.1 - 0.08 12.4 0.0 0.76 9.3 0.0 2.1 2 0 0 2 2 2 0 Staygreen protein EPL1 PF10513.4 KXX78878.1 - 8.9e-32 110.5 3.3 8.9e-32 110.5 2.3 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KXX78879.1 - 3.5e-26 88.4 13.4 4.3e-07 28.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KXX78879.1 - 7.3e-23 80.4 4.2 1.8e-12 47.1 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KXX78879.1 - 5.1e-20 69.5 6.5 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KXX78879.1 - 5.3e-18 63.4 13.1 3.5e-06 26.1 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KXX78879.1 - 5.4e-15 54.7 14.7 1.1e-05 24.9 0.9 4.6 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KXX78879.1 - 6.9e-07 29.2 0.0 0.00045 20.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KXX78879.1 - 8.9e-06 25.3 8.1 0.0077 15.9 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KXX78879.1 - 0.013 15.4 0.1 0.46 10.4 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain VCBS PF13517.1 KXX78879.1 - 0.23 11.8 2.6 10 6.5 0.4 2.8 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Clathrin_lg_ch PF01086.12 KXX78880.1 - 1.2e-73 247.7 4.2 1.4e-73 247.5 2.9 1.0 1 0 0 1 1 1 1 Clathrin light chain Mod_r PF07200.8 KXX78880.1 - 0.047 13.6 2.9 0.087 12.7 2.0 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YscO PF07321.7 KXX78880.1 - 0.077 12.8 9.5 0.14 11.9 6.6 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO Cnl2_NKP2 PF09447.5 KXX78880.1 - 0.9 9.2 4.0 2.3 7.9 2.8 1.7 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Mito_carr PF00153.22 KXX78881.1 - 3.8e-29 100.2 0.3 6.3e-14 51.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HET PF06985.6 KXX78882.1 - 4.3e-23 82.0 8.0 3.5e-20 72.5 0.8 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Herpes_UL32 PF06070.6 KXX78882.1 - 0.039 12.4 1.4 0.059 11.8 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Cupin_8 PF13621.1 KXX78883.1 - 5e-31 108.0 0.0 7.4e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KXX78883.1 - 1.7e-07 30.8 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KXX78883.1 - 0.00024 21.3 0.0 0.0055 16.9 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KXX78883.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain WD40 PF00400.27 KXX78884.1 - 1e-15 56.9 4.4 2.1e-05 24.1 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Sigma70_ner PF04546.8 KXX78884.1 - 0.019 14.5 3.8 0.029 13.9 2.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 KXX78884.1 - 0.027 12.9 1.8 0.039 12.4 1.2 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 KXX78884.1 - 0.057 12.5 5.0 0.083 12.0 3.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Apc4_WD40 PF12894.2 KXX78884.1 - 0.078 12.5 0.1 9.3 5.8 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2457 PF10446.4 KXX78884.1 - 0.29 9.7 18.8 0.45 9.2 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KXX78884.1 - 0.42 10.1 9.7 0.7 9.4 6.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KXX78884.1 - 6.9 4.4 10.4 9.3 4.0 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KXX78884.1 - 7.2 4.5 5.5 10 3.9 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KXX78884.1 - 9.8 6.5 13.6 20 5.5 9.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glycos_transf_4 PF00953.16 KXX78885.1 - 1.3e-32 112.7 10.6 1.3e-32 112.7 7.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 EF-hand_1 PF00036.27 KXX78886.1 - 4.6e-24 81.8 11.5 3.9e-08 32.0 0.2 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KXX78886.1 - 9e-23 78.0 4.0 1.5e-06 27.6 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 KXX78886.1 - 8.4e-22 77.0 2.6 1.7e-13 50.4 0.3 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KXX78886.1 - 9.3e-17 59.5 13.5 2e-05 23.7 0.6 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KXX78886.1 - 4.5e-16 58.2 10.4 2.7e-06 26.8 0.4 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KXX78886.1 - 5.8e-08 32.4 7.1 0.0043 16.7 0.1 3.7 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KXX78886.1 - 0.00024 20.9 0.6 0.0025 17.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 KXX78886.1 - 0.0015 18.1 0.7 0.56 9.9 0.0 3.4 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 KXX78886.1 - 0.0016 18.4 0.8 0.4 10.7 0.1 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 KXX78886.1 - 0.013 15.5 0.2 1 9.4 0.0 2.9 3 1 0 3 3 3 0 EF hand AMP-binding PF00501.23 KXX78887.1 - 2.5e-81 273.2 0.0 3.9e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.11 KXX78887.1 - 0.0039 15.7 0.0 0.0064 15.0 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_23 PF13489.1 KXX78888.1 - 4.3e-18 65.5 0.0 7.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78888.1 - 1.1e-09 38.8 0.3 2e-08 34.7 0.2 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX78888.1 - 1.3e-08 35.1 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX78888.1 - 5.3e-08 32.5 0.1 8.6e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX78888.1 - 1.3e-06 28.7 0.2 1.1e-05 25.8 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX78888.1 - 9.3e-05 22.7 0.0 0.00022 21.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX78888.1 - 0.0081 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KXX78888.1 - 0.013 14.5 0.0 0.044 12.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 KXX78888.1 - 0.044 12.9 0.0 0.19 10.7 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CDC45 PF02724.9 KXX78889.1 - 1.2e-213 710.6 0.0 4.2e-213 708.8 0.0 1.6 1 1 0 1 1 1 1 CDC45-like protein Methyltransf_16 PF10294.4 KXX78890.1 - 2e-14 53.3 0.0 1.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Transglut_core PF01841.14 KXX78891.1 - 1e-09 38.6 0.0 4.1e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF4179 PF13786.1 KXX78892.1 - 1.8 8.8 2.7 1.1 9.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) GST_N_2 PF13409.1 KXX78894.1 - 4.4e-22 77.8 0.0 2.4e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX78894.1 - 1.6e-16 59.9 0.1 3.7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX78894.1 - 2.4e-06 27.4 0.0 5.4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX78894.1 - 3.9e-06 26.9 0.1 0.00024 21.2 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX78894.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UQ_con PF00179.21 KXX78895.1 - 1.6e-23 82.6 0.0 3.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.2 KXX78895.1 - 9.3e-21 73.9 0.6 3.4e-09 36.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX78895.1 - 4.8e-18 63.9 2.7 0.0011 18.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KXX78895.1 - 2.8e-14 52.7 5.7 6.2e-05 23.1 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX78895.1 - 7e-13 48.7 0.8 1.8e-06 28.3 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.7 KXX78895.1 - 7e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 KXX78895.1 - 2.1e-09 36.7 0.3 0.024 14.8 0.0 5.2 4 0 0 4 4 4 1 Ankyrin repeat AAA_16 PF13191.1 KXX78895.1 - 2.5e-05 24.3 0.6 9.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX78895.1 - 0.00031 20.9 0.6 0.0016 18.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 KXX78895.1 - 0.14 11.1 0.2 12 4.8 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain FKBP_C PF00254.23 KXX78896.1 - 7.8e-27 93.1 0.0 9e-27 92.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 KXX78897.1 - 1.3e-50 170.7 0.0 5.2e-32 110.5 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KXX78897.1 - 1.7e-36 123.6 3.9 6.3e-27 92.9 0.3 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KXX78897.1 - 1.2e-30 106.2 0.1 2.9e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KXX78897.1 - 8.1e-22 76.3 2.4 6.6e-19 67.0 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KXX78897.1 - 0.094 12.9 0.0 4.4 7.6 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding MFS_1 PF07690.11 KXX78898.1 - 3.9e-24 85.0 27.3 3.9e-24 85.0 19.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.9 KXX78898.1 - 4.1 5.3 6.8 6 4.7 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CD99L2 PF12301.3 KXX78899.1 - 0.0044 16.7 1.2 0.013 15.1 0.8 1.8 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF3372 PF11852.3 KXX78899.1 - 0.1 11.7 0.2 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) LRR_6 PF13516.1 KXX78900.1 - 0.005 16.7 0.8 14 6.1 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 KXX78900.1 - 0.024 14.6 2.8 13 6.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 KXX78900.1 - 0.028 14.0 7.8 9 6.0 0.4 5.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KXX78900.1 - 2.6 8.6 4.3 3.1e+02 2.3 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat zf-C2H2 PF00096.21 KXX78901.1 - 0.00013 22.1 8.3 0.034 14.4 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX78901.1 - 0.00062 19.9 9.1 0.16 12.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Docking PF08990.6 KXX78901.1 - 0.11 11.7 1.6 0.21 10.8 1.1 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking zf-C2H2_jaz PF12171.3 KXX78901.1 - 0.83 9.8 2.8 3.1 8.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Hexapep PF00132.19 KXX78902.1 - 1.3e-07 30.8 2.2 0.0054 16.1 0.1 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KXX78902.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KXX78902.1 - 0.00037 19.8 0.0 0.00079 18.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KXX78902.1 - 0.12 12.0 8.0 0.24 11.0 1.7 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KXX78902.1 - 0.17 10.4 0.4 0.34 9.4 0.3 1.4 1 0 0 1 1 1 0 L-fucokinase DUF2457 PF10446.4 KXX78902.1 - 4.4 5.9 24.1 6 5.4 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bul1_C PF04426.7 KXX78903.1 - 3.9e-07 29.5 3.0 5.3e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.7 KXX78903.1 - 1.2e-05 24.1 12.5 0.00016 20.3 0.1 3.2 3 1 1 4 4 4 2 Bul1 N terminus Arrestin_C PF02752.17 KXX78903.1 - 0.00012 22.2 2.5 0.46 10.5 1.2 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KXX78903.1 - 0.00097 18.9 0.4 0.01 15.6 0.3 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KXX78903.1 - 0.013 14.3 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Zip PF02535.17 KXX78904.1 - 1.3e-60 205.0 7.2 2.5e-60 204.1 5.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Aconitase PF00330.15 KXX78905.1 - 9.4e-184 611.2 0.0 1.2e-183 610.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KXX78905.1 - 4.1e-45 153.1 0.0 7e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Zn_clus PF00172.13 KXX78906.1 - 0.00061 19.6 3.4 0.0016 18.2 2.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX78906.1 - 0.01 14.4 0.0 0.02 13.4 0.0 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain F-box PF00646.28 KXX78907.1 - 8.4e-07 28.4 0.0 2.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX78907.1 - 3.6e-06 26.5 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KXX78907.1 - 0.073 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Cu_amine_oxid PF01179.15 KXX78908.1 - 4.2e-162 539.6 0.0 5e-162 539.3 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KXX78908.1 - 2.6e-08 33.8 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KXX78908.1 - 0.0079 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain SET PF00856.23 KXX78909.1 - 9.1e-11 42.3 0.0 2.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 SET domain Phage_int_SAM_5 PF13102.1 KXX78909.1 - 0.047 13.7 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain TPR_19 PF14559.1 KXX78909.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CENP-S PF15630.1 KXX78911.1 - 1.9e-33 114.4 0.2 4.6e-33 113.2 0.0 1.6 1 1 1 2 2 2 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KXX78911.1 - 0.0056 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KXX78911.1 - 0.015 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 KXX78911.1 - 0.051 13.3 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KXX78911.1 - 0.064 13.3 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UCH PF00443.24 KXX78912.1 - 1.6e-21 76.6 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KXX78912.1 - 1.1e-11 44.7 0.1 2.3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.27 KXX78913.1 - 1.5e-67 221.2 14.8 4.7e-09 35.7 0.0 11.6 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KXX78913.1 - 2.9e-45 153.3 0.2 4.6e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KXX78913.1 - 4.2e-08 31.7 2.5 0.0027 15.9 0.0 5.0 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX78913.1 - 9.7e-05 21.2 5.6 1.2 7.8 0.0 4.7 4 2 0 4 4 4 3 Nup133 N terminal like AAA_16 PF13191.1 KXX78914.1 - 2.1e-05 24.6 2.7 0.00057 19.9 0.6 2.9 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KXX78914.1 - 9.9e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KXX78914.1 - 0.018 14.4 0.3 0.16 11.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 KXX78914.1 - 0.026 15.0 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KXX78914.1 - 0.039 14.0 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KXX78914.1 - 0.084 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KXX78914.1 - 0.094 12.2 0.0 0.39 10.1 0.0 1.9 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KXX78916.1 - 7.9e-11 41.8 0.0 2.6e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX78916.1 - 1e-06 28.8 0.3 1e-06 28.8 0.2 2.4 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 KXX78916.1 - 9.8e-06 24.6 0.0 2.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KXX78916.1 - 0.0029 17.7 0.1 0.24 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain HTH_30 PF13556.1 KXX78916.1 - 0.03 13.9 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain APS_kinase PF01583.15 KXX78916.1 - 0.066 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KXX78916.1 - 0.067 12.1 0.1 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.1 KXX78916.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX78916.1 - 0.18 12.6 0.2 0.78 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain Fez1 PF06818.10 KXX78916.1 - 0.59 10.1 4.0 0.43 10.5 0.6 2.0 2 0 0 2 2 2 0 Fez1 Fungal_trans_2 PF11951.3 KXX78917.1 - 5.5e-33 114.1 0.4 1e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78917.1 - 2e-08 34.0 11.5 3.3e-08 33.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 KXX78918.1 - 6.1e-10 38.6 0.6 2.9e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KXX78918.1 - 1.5e-05 24.3 0.2 0.18 11.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78918.1 - 4.4e-05 23.0 1.9 0.69 9.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.26 KXX78918.1 - 0.00012 21.7 0.1 0.00076 19.2 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 KXX78918.1 - 0.0079 15.9 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 KXX78918.1 - 0.053 13.8 1.1 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat APS_kinase PF01583.15 KXX78918.1 - 0.079 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_12 PF13424.1 KXX78918.1 - 0.63 10.0 5.8 0.25 11.3 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1996 PF09362.5 KXX78919.1 - 4.5e-77 258.8 0.1 5.7e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CENP-B_dimeris PF09026.5 KXX78920.1 - 0.0085 16.3 0.3 0.016 15.4 0.2 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Gemini_mov PF01708.11 KXX78920.1 - 0.16 11.5 0.3 0.46 10.0 0.2 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein LSM PF01423.17 KXX78922.1 - 4.8e-15 54.8 0.3 6.7e-15 54.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Ammonium_transp PF00909.16 KXX78923.1 - 0.022 13.2 0.8 0.036 12.5 0.6 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family UQ_con PF00179.21 KXX78924.1 - 8.4e-52 174.3 0.0 9.4e-52 174.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MTHFR PF02219.12 KXX78925.1 - 5.3e-101 337.4 0.0 8.2e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.13 KXX78926.1 - 2.2e-51 173.6 0.0 2.2e-51 173.6 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E DUF572 PF04502.8 KXX78927.1 - 1.6e-68 231.3 1.8 1.6e-67 228.0 0.9 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF572) HBS1_N PF08938.5 KXX78927.1 - 0.055 13.6 1.1 0.094 12.8 0.8 1.3 1 0 0 1 1 1 0 HBS1 N-terminus Glyco_hydro_18 PF00704.23 KXX78928.1 - 6.5e-15 55.4 0.0 1.4e-14 54.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Glyco_transf_15 PF01793.11 KXX78929.1 - 1.1e-137 458.4 7.5 1.3e-137 458.1 5.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 KXX78930.1 - 2.8e-71 240.4 0.0 3.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KXX78930.1 - 0.00012 20.3 0.0 0.00039 18.6 0.0 1.8 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Zn_clus PF00172.13 KXX78931.1 - 2.1e-06 27.5 8.6 3.6e-06 26.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KXX78932.1 - 4.3e-27 92.9 7.9 7.3e-08 32.0 0.4 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ PF01011.16 KXX78932.1 - 0.1 12.1 3.2 4.8 6.8 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat PQ-loop PF04193.9 KXX78934.1 - 1.2e-19 69.5 6.5 3e-13 49.0 2.0 2.8 2 0 0 2 2 2 2 PQ loop repeat HET PF06985.6 KXX78936.1 - 5.4e-28 97.9 0.2 9.4e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_M PF01068.16 KXX78937.1 - 1.7e-45 154.9 0.0 2.9e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KXX78937.1 - 4.4e-35 121.0 0.0 7.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KXX78937.1 - 4.8e-16 58.9 0.2 3.9e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KXX78937.1 - 4e-07 30.1 0.0 1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KXX78937.1 - 0.0022 17.7 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 KXX78937.1 - 0.018 14.7 0.1 0.75 9.4 0.0 2.7 2 2 0 2 2 2 0 mRNA capping enzyme, catalytic domain ATG16 PF08614.6 KXX78938.1 - 2.9e-49 167.5 6.7 3.3e-49 167.3 4.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AIP3 PF03915.8 KXX78938.1 - 0.00025 20.0 4.0 0.016 14.1 0.9 2.0 2 0 0 2 2 2 2 Actin interacting protein 3 CCDC144C PF14915.1 KXX78938.1 - 0.00034 19.6 9.8 0.0074 15.2 5.3 2.0 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region HALZ PF02183.13 KXX78938.1 - 0.025 14.2 0.1 0.14 11.8 0.0 2.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4201 PF13870.1 KXX78938.1 - 0.058 12.8 12.8 0.04 13.3 6.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 KXX78938.1 - 0.073 13.3 12.6 1.6 9.0 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF904) IncA PF04156.9 KXX78938.1 - 0.079 12.5 8.1 0.019 14.5 2.6 1.9 2 0 0 2 2 2 0 IncA protein SPX PF03105.14 KXX78938.1 - 0.08 12.7 1.5 0.1 12.3 1.0 1.1 1 0 0 1 1 1 0 SPX domain Psb28 PF03912.9 KXX78938.1 - 0.21 11.5 2.1 0.49 10.3 1.4 1.6 1 1 0 1 1 1 0 Psb28 protein Atg14 PF10186.4 KXX78938.1 - 0.41 9.5 12.2 0.6 8.9 8.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF940 PF06082.6 KXX78938.1 - 0.59 8.6 2.9 0.63 8.5 2.0 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF4140 PF13600.1 KXX78938.1 - 0.74 10.2 18.5 0.36 11.2 0.5 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.1 KXX78938.1 - 0.77 8.9 12.6 2.5 7.2 6.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 KXX78938.1 - 0.79 8.3 5.4 1.2 7.7 3.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TSC22 PF01166.13 KXX78938.1 - 1.9 8.4 8.0 6.6 6.7 1.7 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4061 PF13270.1 KXX78938.1 - 3.3 7.8 8.0 1.4 9.0 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DOT1 PF08123.8 KXX78939.1 - 3.1e-72 242.2 0.0 4.8e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KXX78939.1 - 5.2e-06 26.1 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX78939.1 - 8e-06 25.8 0.0 2.5e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX78939.1 - 0.0011 19.5 0.1 0.0031 18.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF1129 PF06570.6 KXX78939.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Mucin PF01456.12 KXX78940.1 - 0.00013 21.7 7.3 0.00019 21.2 5.1 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.6 KXX78940.1 - 0.003 17.3 5.2 0.0057 16.4 3.6 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Peptidase_M16_C PF05193.16 KXX78941.1 - 2.2e-57 193.6 0.0 1e-56 191.5 0.0 2.1 2 2 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KXX78941.1 - 3.3e-43 146.9 0.0 6.6e-43 146.0 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.9 KXX78941.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Disulph_isomer PF06491.6 KXX78941.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase S1 PF00575.18 KXX78943.1 - 3.8e-97 318.4 29.1 1.2e-18 66.8 0.1 13.7 14 0 0 14 14 14 12 S1 RNA binding domain TPR_19 PF14559.1 KXX78943.1 - 4.3e-08 33.3 0.5 0.00043 20.5 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX78943.1 - 2.4e-07 30.7 7.5 0.046 14.3 0.0 5.6 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX78943.1 - 1.2e-05 24.8 0.1 0.00021 20.8 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 KXX78943.1 - 1.9e-05 25.2 2.5 0.0023 18.5 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Suf PF05843.9 KXX78943.1 - 0.00019 21.2 6.8 0.0076 16.0 0.0 3.7 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_6 PF13174.1 KXX78943.1 - 0.0026 18.0 0.2 11 6.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX78943.1 - 0.005 16.7 0.1 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78943.1 - 0.0052 16.5 0.1 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX78943.1 - 0.0081 16.2 0.5 4.2 7.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat S1_2 PF13509.1 KXX78943.1 - 0.01 15.7 0.1 50 3.9 0.0 5.0 5 0 0 5 5 4 0 S1 domain Ras_bdg_2 PF14847.1 KXX78943.1 - 0.011 15.6 0.3 4 7.4 0.0 3.2 3 0 0 3 3 2 0 Ras-binding domain of Byr2 TPR_7 PF13176.1 KXX78943.1 - 0.037 13.8 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 KXX78946.1 - 1e-74 252.3 8.6 1.4e-74 251.8 6.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) LOH1CR12 PF10158.4 KXX78946.1 - 0.19 11.4 2.9 11 5.8 1.5 3.1 3 0 0 3 3 3 0 Tumour suppressor protein Spectrin PF00435.16 KXX78946.1 - 9.3 6.5 18.9 0.15 12.3 1.2 3.9 3 1 0 3 3 3 0 Spectrin repeat p450 PF00067.17 KXX78948.1 - 3.3e-32 111.6 0.0 6.5e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Vps16_N PF04841.8 KXX78949.1 - 4.1e-96 322.0 0.0 5.7e-96 321.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KXX78949.1 - 4.2e-74 249.3 0.0 6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 KXX78950.1 - 2.3e-16 59.6 0.0 6.6e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KXX78950.1 - 5.9e-06 26.0 11.9 9.5e-06 25.3 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KXX78950.1 - 0.00025 21.0 5.5 0.00043 20.3 3.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HC5HC2H PF13771.1 KXX78950.1 - 0.022 14.9 1.9 0.041 14.0 1.3 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4 PF00097.20 KXX78950.1 - 0.037 13.6 12.5 0.066 12.8 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX78950.1 - 0.059 13.2 2.5 0.099 12.4 1.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 KXX78950.1 - 0.2 11.3 7.0 0.35 10.5 4.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KXX78950.1 - 0.29 10.8 9.5 0.49 10.1 6.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 KXX78950.1 - 2.3 8.2 7.9 3.9 7.5 5.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 KXX78950.1 - 2.8 8.0 14.0 5 7.2 9.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.3 KXX78950.1 - 3.1 7.5 10.5 2.1 8.1 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UPRTase PF14681.1 KXX78952.1 - 2.5e-74 248.9 0.0 2.9e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KXX78952.1 - 5e-07 29.4 0.0 1e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KXX78952.1 - 0.048 12.7 0.6 0.21 10.6 0.2 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Pribosyl_synth PF14572.1 KXX78952.1 - 0.085 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CRCB PF02537.10 KXX78953.1 - 5.4e-28 97.2 24.5 2e-18 66.3 5.8 3.9 3 1 1 4 4 4 3 CrcB-like protein DUF4449 PF14613.1 KXX78954.1 - 2.7e-66 222.5 0.5 2.7e-66 222.5 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF4404 PF14357.1 KXX78954.1 - 0.0062 16.9 2.8 4 7.9 0.1 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF4404) ApoLp-III PF07464.6 KXX78954.1 - 0.64 10.0 10.6 0.063 13.3 1.7 3.2 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TPPII_N PF12583.3 KXX78954.1 - 1.3 9.1 7.9 0.041 14.0 0.7 2.0 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal tRNA-synt_1g PF09334.6 KXX78955.1 - 9.1e-137 455.8 0.0 6.3e-136 453.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KXX78955.1 - 1.4e-09 36.5 0.2 0.0026 15.8 0.0 4.2 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) DUF1682 PF07946.9 KXX78955.1 - 1.3 7.7 5.1 2.2 7.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Lactamase_B_2 PF12706.2 KXX78956.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX78956.1 - 8.9e-09 35.2 0.1 3e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily HET PF06985.6 KXX78958.1 - 1.1e-22 80.7 0.0 6.5e-22 78.1 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_BLLF1 PF05109.8 KXX78958.1 - 0.29 9.0 2.5 0.42 8.5 1.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ABA_GPCR PF12430.3 KXX78960.1 - 7e-53 178.6 0.0 3.6e-52 176.3 0.0 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KXX78960.1 - 6.5e-20 70.9 0.0 7.1e-19 67.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Ank_2 PF12796.2 KXX78961.1 - 1.6e-20 73.2 3.1 4.9e-10 39.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX78961.1 - 2.2e-16 58.7 3.7 0.00011 21.8 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KXX78961.1 - 9.1e-14 51.5 2.6 2.3e-05 24.7 0.0 4.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78961.1 - 2.2e-12 45.9 3.0 0.0045 17.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KXX78961.1 - 6.7e-09 35.7 3.7 0.018 15.2 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TPR_12 PF13424.1 KXX78961.1 - 0.0045 16.8 0.2 0.02 14.7 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX78961.1 - 0.26 12.0 2.8 0.44 11.2 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX78961.1 - 0.57 10.2 3.6 0.73 9.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KXX78963.1 - 1.6e-40 139.0 8.1 1.2e-34 119.7 5.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX78963.1 - 0.00056 18.7 4.0 0.00056 18.7 2.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Neisseria_TspB PF05616.8 KXX78964.1 - 2.2 6.5 5.5 2.5 6.3 3.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4501 PF14946.1 KXX78966.1 - 0.032 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) PEX11 PF05648.9 KXX78967.1 - 0.06 12.5 5.6 6.4 5.9 0.1 3.4 2 1 1 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) DnaJ PF00226.26 KXX78969.1 - 6.5e-19 67.4 0.4 2.2e-18 65.7 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain IncA PF04156.9 KXX78969.1 - 0.024 14.2 0.7 0.024 14.2 0.5 3.3 2 1 1 3 3 3 0 IncA protein Pkinase PF00069.20 KXX78970.1 - 1.2e-17 63.9 0.0 3.5e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX78970.1 - 6.4e-10 38.5 0.0 2.2e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Nup54 PF13874.1 KXX78970.1 - 0.1 12.2 3.5 0.24 11.0 2.4 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LysM PF01476.15 KXX78971.1 - 7.5e-20 70.5 0.3 1.5e-06 27.9 0.0 4.1 4 0 0 4 4 4 3 LysM domain HTH_Tnp_1 PF01527.15 KXX78971.1 - 0.012 15.5 0.0 18 5.3 0.0 3.1 3 0 0 3 3 3 0 Transposase TroA PF01297.12 KXX78971.1 - 0.013 14.7 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Periplasmic solute binding protein family UPF0203 PF05254.7 KXX78971.1 - 0.18 11.6 4.9 20 5.1 0.4 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0203) Prp19_bind PF06991.6 KXX78972.1 - 1.6e-48 165.3 33.8 1.6e-48 165.3 23.4 2.5 3 1 1 4 4 4 1 Splicing factor, Prp19-binding domain Voldacs PF03517.8 KXX78974.1 - 3.1e-22 78.8 0.5 3.1e-22 78.8 0.3 1.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Hydrolase PF00702.21 KXX78975.1 - 1.5e-19 71.2 0.0 5.8e-19 69.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KXX78975.1 - 5e-16 58.4 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KXX78975.1 - 1.8e-15 57.5 0.0 9.9e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX78975.1 - 3.7e-12 46.0 0.0 1.7e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KXX78975.1 - 0.00097 18.7 0.0 0.0073 15.9 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KXX78975.1 - 0.021 15.0 0.1 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ADH_zinc_N_2 PF13602.1 KXX78976.1 - 3.2e-15 57.1 0.0 7e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KXX78976.1 - 0.041 13.6 1.1 0.081 12.7 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 KXX78976.1 - 0.05 13.1 0.1 0.25 10.8 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DapB_N PF01113.15 KXX78976.1 - 0.064 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gcd10p PF04189.8 KXX78976.1 - 0.25 10.4 0.1 0.39 9.7 0.1 1.2 1 0 0 1 1 1 0 Gcd10p family CRAL_TRIO PF00650.15 KXX78977.1 - 9.7e-41 138.9 0.0 1.4e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX78977.1 - 4.7e-08 33.0 0.7 9.5e-08 32.0 0.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KXX78977.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 KXX78978.1 - 2.7e-63 213.8 0.0 3.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KXX78978.1 - 4.8e-40 137.0 0.0 6.7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Glyco_hydro_18 PF00704.23 KXX78980.1 - 7.8e-45 153.8 0.2 1.3e-44 153.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KXX78980.1 - 2.5e-30 104.2 2.7 7.7e-30 102.6 0.5 2.5 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KXX78980.1 - 2.8e-11 43.1 0.0 0.00037 20.3 0.0 3.0 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KXX78980.1 - 7.3e-05 22.6 2.5 7.3e-05 22.6 1.7 3.4 2 0 0 2 2 2 1 Chitin recognition protein HTH_Tnp_1 PF01527.15 KXX78982.1 - 0.085 12.8 2.9 0.4 10.6 0.3 2.9 2 1 1 3 3 3 0 Transposase PAN_1 PF00024.21 KXX78984.1 - 6.1e-06 25.8 0.1 1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 KXX78984.1 - 1e-05 24.8 0.0 2.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KXX78984.1 - 0.00032 20.3 0.0 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase PNP_UDP_1 PF01048.15 KXX78986.1 - 1.3e-14 53.7 0.0 2.7e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.1 KXX78986.1 - 4.1e-10 39.9 0.1 5.9e-07 29.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.17 KXX78986.1 - 6.8e-08 31.7 0.0 1.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KXX78986.1 - 0.00024 20.8 0.0 0.00056 19.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KXX78986.1 - 0.0053 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KXX78986.1 - 0.0089 16.0 0.6 0.11 12.5 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KXX78986.1 - 0.0098 15.3 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX78986.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_14 PF13428.1 KXX78986.1 - 0.1 13.3 2.7 5.5 7.9 1.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KXX78987.1 - 5.3e-14 51.7 1.5 7.3e-14 51.2 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vps54 PF07928.7 KXX78988.1 - 5.5e-38 130.1 0.2 9.4e-37 126.1 0.1 2.4 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KXX78988.1 - 0.00022 20.2 0.8 0.00045 19.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) HAUS5 PF14817.1 KXX78988.1 - 0.00038 19.1 0.3 0.00093 17.8 0.0 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 5 DUF3435 PF11917.3 KXX78989.1 - 0.0038 16.0 1.4 0.0053 15.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Zn_clus PF00172.13 KXX78991.1 - 1.1e-05 25.2 6.4 1.1e-05 25.2 4.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox PF00046.24 KXX78992.1 - 6.4e-20 70.5 4.8 1.4e-19 69.4 3.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KXX78992.1 - 0.00018 21.1 0.7 0.00061 19.4 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain Fungal_trans_2 PF11951.3 KXX78993.1 - 4e-11 42.1 0.5 9e-06 24.5 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX78993.1 - 0.051 13.5 3.3 0.13 12.1 2.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lung_7-TM_R PF06814.8 KXX78994.1 - 1.2e-72 244.3 18.2 1.5e-72 244.0 12.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 KXX78994.1 - 1.3 8.4 17.6 0.16 11.3 1.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_28 PF02636.12 KXX78995.1 - 2e-77 260.0 0.0 3e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pro_isomerase PF00160.16 KXX78996.1 - 1.1e-43 149.1 0.0 1.9e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KXX78996.1 - 6.4e-05 22.8 0.0 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.7 KXX78996.1 - 0.0009 18.5 0.0 0.002 17.3 0.0 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger Ank PF00023.25 KXX78997.1 - 2.5e-81 263.6 1.1 1e-07 31.3 0.1 14.6 14 0 0 14 14 14 13 Ankyrin repeat Ank_2 PF12796.2 KXX78997.1 - 2.7e-80 264.7 10.1 3.2e-16 59.4 0.2 9.1 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX78997.1 - 6.2e-64 211.3 9.3 2e-10 40.8 0.0 12.0 5 2 9 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX78997.1 - 3.2e-52 173.3 9.4 1.4e-08 34.6 0.1 11.3 3 1 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX78997.1 - 9.7e-51 164.6 0.0 0.00014 21.7 0.0 15.6 15 0 0 15 15 15 10 Ankyrin repeat YscJ_FliF PF01514.12 KXX78997.1 - 0.031 13.4 0.3 0.12 11.5 0.0 2.0 2 1 1 3 3 3 0 Secretory protein of YscJ/FliF family Gal-3-0_sulfotr PF06990.6 KXX78997.1 - 0.37 9.3 1.0 0.65 8.5 0.7 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Hemerythrin PF01814.18 KXX78998.1 - 3.3e-13 49.9 0.1 4.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_Gp14 PF10666.4 KXX78998.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Phage protein Gp14 MFS_1 PF07690.11 KXX78999.1 - 3.8e-39 134.4 61.4 3e-38 131.4 40.8 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX78999.1 - 8.1e-10 37.8 15.0 8.1e-10 37.8 10.4 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 KXX79001.1 - 7.2e-07 28.8 0.4 0.00049 19.8 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat NACHT PF05729.7 KXX79001.1 - 4.4e-05 23.2 0.0 0.00018 21.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KXX79001.1 - 0.00014 21.7 0.0 0.00047 20.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX79001.1 - 0.00042 19.9 0.1 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KXX79001.1 - 0.0035 16.6 0.0 0.0082 15.4 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 KXX79001.1 - 0.018 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_5 PF12695.2 KXX79001.1 - 0.041 13.6 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3647 PF12363.3 KXX79001.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage protein Coatomer_WDAD PF04053.9 KXX79001.1 - 0.31 9.7 0.0 16 4.1 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region ArgK PF03308.11 KXX79001.1 - 0.31 9.7 0.0 0.61 8.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 KXX79001.1 - 0.44 9.4 0.0 0.69 8.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HET PF06985.6 KXX79002.1 - 8.8e-28 97.2 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 KXX79003.1 - 1.7e-19 70.3 0.0 3.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX79003.1 - 0.00043 21.0 0.0 0.002 18.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX79003.1 - 0.0011 19.1 0.1 0.006 16.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX79003.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KXX79003.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KXX79003.1 - 0.026 14.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KXX79003.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KXX79003.1 - 0.06 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KXX79003.1 - 0.09 11.8 1.1 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KXX79003.1 - 0.13 12.0 0.4 0.32 10.7 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 KXX79003.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activat PF00158.21 KXX79003.1 - 0.29 10.5 0.0 0.52 9.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RRM_6 PF14259.1 KXX79004.1 - 0.038 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79004.1 - 0.099 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEP_mutase PF13714.1 KXX79005.1 - 9.2e-44 149.4 4.4 1.1e-43 149.2 3.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KXX79005.1 - 4e-19 68.2 1.4 5.9e-19 67.6 0.9 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF1900 PF08954.6 KXX79006.1 - 9.1e-50 167.7 0.0 1.1e-48 164.2 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KXX79006.1 - 2.5e-35 119.9 0.0 4.3e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KXX79006.1 - 2.5e-24 84.2 3.6 4e-07 29.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 KXX79006.1 - 0.0075 16.0 0.0 0.03 14.0 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A SlyX PF04102.7 KXX79006.1 - 0.086 13.2 5.8 0.38 11.1 2.0 2.4 2 0 0 2 2 2 0 SlyX Nup160 PF11715.3 KXX79006.1 - 0.14 10.3 7.0 0.089 10.9 0.2 2.9 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Ank_2 PF12796.2 KXX79008.1 - 4.6e-39 132.6 2.0 4.8e-13 49.2 0.0 4.4 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79008.1 - 1.6e-23 81.2 8.3 0.0012 18.4 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 KXX79008.1 - 2e-17 61.5 0.7 0.029 14.5 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KXX79008.1 - 9.5e-15 54.6 0.1 0.00013 22.4 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX79008.1 - 8.5e-11 41.7 2.5 0.0014 18.8 0.1 5.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 KXX79008.1 - 2.2e-10 40.4 0.1 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX79008.1 - 1.8e-06 28.1 3.0 1.5e-05 25.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 KXX79008.1 - 0.00011 21.3 0.3 0.063 12.2 0.0 2.7 3 0 0 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.1 KXX79008.1 - 0.00057 20.0 0.3 0.0035 17.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KXX79009.1 - 1.1e-16 60.5 0.0 2.3e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KXX79009.1 - 0.001 19.1 0.3 0.0019 18.2 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 KXX79009.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 KXX79009.1 - 0.032 14.3 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KXX79009.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 KXX79009.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.4 KXX79009.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 KXX79009.1 - 0.15 12.4 0.0 0.23 11.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.20 KXX79010.1 - 1e-62 211.6 0.0 1.7e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79010.1 - 6.6e-31 107.3 0.0 1.6e-30 106.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79010.1 - 1.2e-05 24.4 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX79010.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX79010.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family DUF3987 PF13148.1 KXX79010.1 - 1.5 7.3 8.5 2.2 6.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtf2 PF04641.7 KXX79010.1 - 4.4 6.4 10.0 8.7 5.4 6.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger eIF3_subunit PF08597.5 KXX79010.1 - 7.2 6.0 15.1 11 5.5 10.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Aminotran_3 PF00202.16 KXX79011.1 - 1e-105 353.3 0.0 1.2e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KXX79011.1 - 9.1e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KXX79011.1 - 0.016 14.1 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_22 PF03901.12 KXX79012.1 - 3.4e-78 263.5 16.8 4e-78 263.2 11.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 KXX79012.1 - 0.068 13.2 0.3 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) MFS_1 PF07690.11 KXX79013.1 - 2.2e-33 115.4 26.6 8.3e-33 113.5 18.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 KXX79013.1 - 0.0037 16.1 12.2 0.0037 16.1 8.5 2.7 2 1 1 3 3 3 1 Acyltransferase family DUF3543 PF12063.3 KXX79014.1 - 5.9e-95 317.0 1.8 8.7e-95 316.4 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KXX79014.1 - 5.4e-61 206.0 0.0 1.1e-60 205.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79014.1 - 9e-41 139.6 0.0 1.9e-40 138.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.22 KXX79015.1 - 1.1e-38 132.2 0.0 1.8e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Nup188 PF10487.4 KXX79017.1 - 4.8e-29 100.9 0.0 6.6e-25 87.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.10 KXX79018.1 - 2.8e-20 71.3 0.4 3.7e-20 70.9 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HATPase_c_5 PF14501.1 KXX79018.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 GHKL domain DUF842 PF05811.8 KXX79018.1 - 0.021 14.3 1.0 0.49 9.8 0.4 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Thionin PF00321.12 KXX79018.1 - 0.095 12.9 1.2 0.14 12.3 0.8 1.3 1 0 0 1 1 1 0 Plant thionin INCENP_ARK-bind PF03941.10 KXX79018.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Use1 PF09753.4 KXX79019.1 - 0.00021 20.8 0.9 0.00021 20.8 0.6 2.0 1 1 1 2 2 2 1 Membrane fusion protein Use1 Snapin_Pallidin PF14712.1 KXX79019.1 - 0.054 13.7 1.1 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF605 PF04652.11 KXX79019.1 - 0.07 12.5 25.9 0.09 12.1 17.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF3347 PF11827.3 KXX79019.1 - 0.23 11.4 5.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) PAT1 PF09770.4 KXX79019.1 - 1.1 7.3 14.2 1.3 7.1 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 KXX79019.1 - 2.1 5.8 6.0 3.3 5.2 4.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IGPS PF00218.16 KXX79020.1 - 1.5e-97 325.6 0.0 2.6e-97 324.8 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KXX79020.1 - 9.1e-51 172.0 0.0 1.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 KXX79020.1 - 7.1e-50 169.3 0.0 2.4e-45 154.5 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KXX79020.1 - 1.2e-05 24.9 0.1 5.2e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KXX79020.1 - 0.013 15.0 0.2 0.12 11.8 0.0 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KXX79020.1 - 0.069 12.3 0.1 0.59 9.3 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein Herpes_gE PF02480.11 KXX79021.1 - 0.0048 15.2 0.1 0.0085 14.4 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KXX79021.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TFIIA PF03153.8 KXX79021.1 - 8 6.2 11.2 11 5.7 7.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med5 PF08689.5 KXX79022.1 - 4.1e-249 829.1 0.0 5.4e-249 828.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF2593 PF10767.4 KXX79022.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) B-block_TFIIIC PF04182.7 KXX79023.1 - 2.6e-16 59.2 0.0 1.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Pkinase PF00069.20 KXX79025.1 - 4.6e-08 32.5 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KXX79025.1 - 0.057 12.4 0.0 0.32 10.0 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KXX79025.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ebp2 PF05890.7 KXX79027.1 - 6.6e-93 310.9 17.3 6.6e-93 310.9 12.0 2.0 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 zf-MYND PF01753.13 KXX79028.1 - 2.6e-08 33.5 20.0 6.5e-08 32.3 13.9 1.7 1 0 0 1 1 1 1 MYND finger Cyanate_lyase PF02560.9 KXX79030.1 - 1.4e-29 101.3 0.0 2e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KXX79030.1 - 1.2e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KXX79030.1 - 0.0022 17.4 0.0 0.008 15.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.17 KXX79030.1 - 0.0053 16.5 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.1 KXX79030.1 - 0.039 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.1 KXX79030.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.18 KXX79031.1 - 3.3e-113 377.7 0.0 4.2e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 KXX79031.1 - 0.97 9.2 5.6 0.7 9.6 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function DUF87 DUF972 PF06156.8 KXX79031.1 - 4.3 7.7 5.5 24 5.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) PUL PF08324.6 KXX79032.1 - 3.9e-39 134.0 0.0 5.4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KXX79032.1 - 1.1e-32 112.9 0.0 2e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KXX79032.1 - 2.4e-13 49.6 0.0 4.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX79032.1 - 0.0013 18.8 0.1 0.0066 16.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KXX79032.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 KXX79032.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.1 KXX79032.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 KXX79032.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain GDA1_CD39 PF01150.12 KXX79033.1 - 4.9e-89 298.8 0.0 6e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_3 PF07726.6 KXX79034.1 - 0.0044 16.6 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cation_efflux PF01545.16 KXX79035.1 - 6e-21 74.7 16.4 1.1e-17 64.0 9.5 2.2 2 0 0 2 2 2 2 Cation efflux family Peptidase_M16_C PF05193.16 KXX79037.1 - 3.8e-18 65.8 0.0 1.7e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KXX79037.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TRAP_alpha PF03896.11 KXX79038.1 - 3.4e-05 22.9 0.1 0.00018 20.6 0.1 2.0 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit EamA PF00892.15 KXX79039.1 - 1.4e-07 31.5 27.9 5.8e-07 29.6 1.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KXX79039.1 - 5.5e-06 25.5 6.5 1.1e-05 24.5 4.5 1.4 1 0 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 KXX79039.1 - 8e-06 24.9 7.0 8e-06 24.9 4.9 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KXX79039.1 - 0.00011 22.3 4.6 0.00011 22.3 3.2 3.6 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF3955 PF13127.1 KXX79039.1 - 0.00041 19.8 1.1 0.00041 19.8 0.8 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) TPT PF03151.11 KXX79039.1 - 0.0034 17.0 2.2 0.0034 17.0 1.6 2.9 3 0 0 3 3 3 2 Triose-phosphate Transporter family Spb1_C PF07780.7 KXX79040.1 - 9.1e-77 257.3 26.8 9.1e-77 257.3 18.6 3.5 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KXX79040.1 - 2.2e-56 189.7 11.5 2.2e-56 189.7 8.0 4.8 3 2 2 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KXX79040.1 - 2.2e-54 184.2 0.0 3.9e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.27 KXX79041.1 - 4.1e-25 86.6 1.6 1e-06 28.3 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KXX79041.1 - 0.019 13.1 0.0 0.095 10.8 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Met_asp_mut_E PF06368.6 KXX79041.1 - 0.3 9.1 0.0 0.47 8.5 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Sterol-sensing PF12349.3 KXX79042.1 - 1.1e-35 122.4 4.6 1.1e-35 122.4 3.2 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KXX79042.1 - 1.3e-08 33.2 0.7 1.8e-08 32.7 0.5 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 KXX79042.1 - 0.031 14.1 0.1 3 7.8 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Cupin_8 PF13621.1 KXX79043.1 - 2.6e-66 223.7 0.0 3.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KXX79043.1 - 2.9e-05 23.4 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KXX79043.1 - 0.094 12.9 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 JmjC domain, hydroxylase AvrPto PF11592.3 KXX79043.1 - 0.16 11.7 0.1 0.5 10.1 0.0 1.8 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto 14-3-3 PF00244.15 KXX79044.1 - 2.5e-08 33.3 0.1 8.1e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein FMN_dh PF01070.13 KXX79045.1 - 7.1e-101 337.5 0.0 9.5e-101 337.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KXX79045.1 - 1.5e-17 63.1 0.0 2.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KXX79045.1 - 0.00011 21.1 0.1 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KXX79045.1 - 0.002 17.1 2.3 0.09 11.6 0.0 3.2 4 0 0 4 4 4 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KXX79045.1 - 0.041 12.8 0.1 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF4202 PF13875.1 KXX79046.1 - 4.4e-76 254.6 0.2 5e-76 254.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Dynamin_N PF00350.18 KXX79047.1 - 3.9e-42 143.9 0.0 8.7e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX79047.1 - 2.6e-05 23.1 0.1 6.8e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KXX79047.1 - 0.0012 18.7 0.0 0.0055 16.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KXX79047.1 - 0.0028 18.1 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KXX79047.1 - 0.04 13.8 0.4 0.2 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 KXX79047.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 KXX79048.1 - 4.2e-18 65.0 0.0 4.3e-16 58.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KXX79048.1 - 8.8e-09 35.4 0.0 2.2e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KXX79048.1 - 1.1e-06 27.6 0.0 6.7e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Ras PF00071.17 KXX79049.1 - 8.3e-57 191.0 0.0 9.9e-57 190.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX79049.1 - 3e-18 66.4 0.0 4.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX79049.1 - 1.4e-13 50.4 0.0 1.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KXX79049.1 - 5.4e-08 32.7 0.0 7.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KXX79049.1 - 1.1e-07 31.2 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KXX79049.1 - 1.2e-06 28.1 0.0 2.4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KXX79049.1 - 0.00072 19.7 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KXX79049.1 - 0.00095 18.3 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KXX79049.1 - 0.0013 18.4 0.0 0.0047 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KXX79049.1 - 0.0016 17.7 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 KXX79049.1 - 0.0043 16.6 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX79049.1 - 0.0051 16.8 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 KXX79049.1 - 0.0051 16.3 0.3 0.17 11.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KXX79049.1 - 0.0051 16.5 0.1 0.0094 15.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 KXX79049.1 - 0.0069 15.8 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KXX79049.1 - 0.0069 15.8 0.2 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Septin PF00735.13 KXX79049.1 - 0.013 14.5 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Septin MobB PF03205.9 KXX79049.1 - 0.023 14.3 0.1 0.056 13.1 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KXX79049.1 - 0.026 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.14 KXX79049.1 - 0.039 13.3 0.0 0.12 11.8 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KXX79049.1 - 0.057 13.5 0.1 0.27 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 KXX79049.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 KXX79049.1 - 0.088 12.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.17 KXX79049.1 - 0.22 10.3 0.7 0.37 9.5 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF605 PF04652.11 KXX79052.1 - 0.47 9.7 21.0 0.64 9.3 14.6 1.2 1 0 0 1 1 1 0 Vta1 like FAD_binding_3 PF01494.14 KXX79053.1 - 8.1e-11 41.5 0.1 3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KXX79053.1 - 0.0024 16.7 0.0 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Phage_C PF12025.3 KXX79053.1 - 0.0043 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Phage protein C Mem_trans PF03547.13 KXX79054.1 - 1.2e-21 76.4 0.5 1.8e-21 75.9 0.4 1.2 1 0 0 1 1 1 1 Membrane transport protein p450 PF00067.17 KXX79056.1 - 3.1e-26 91.9 0.0 4.1e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 KXX79057.1 - 4.6e-09 36.5 0.1 6.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX79057.1 - 0.0035 16.6 0.0 0.034 13.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family HET PF06985.6 KXX79059.1 - 1e-22 80.8 4.8 2e-19 70.1 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MoaC PF01967.16 KXX79060.1 - 4.9e-53 178.4 2.0 7.5e-53 177.8 1.4 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KXX79060.1 - 1.7e-33 115.0 0.0 6.9e-33 113.0 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KXX79060.1 - 9.8e-19 68.1 0.0 1.9e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KXX79060.1 - 2.3e-05 24.5 0.0 0.00091 19.3 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KXX79060.1 - 0.00016 21.6 0.0 0.0047 16.9 0.0 2.8 2 1 0 3 3 3 1 4Fe-4S single cluster domain WD40 PF00400.27 KXX79061.1 - 0.0025 17.6 16.0 1.5 8.8 0.0 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat IKI3 PF04762.7 KXX79061.1 - 0.088 10.6 0.0 14 3.3 0.0 3.2 3 1 1 4 4 4 0 IKI3 family FYVE PF01363.16 KXX79062.1 - 7.9e-16 57.7 7.8 1.3e-15 56.9 5.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KXX79062.1 - 2.7 7.9 14.3 0.94 9.4 7.2 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Synaptobrevin PF00957.16 KXX79063.1 - 1.2e-14 53.7 0.6 1.8e-14 53.0 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KXX79063.1 - 1.2e-13 50.4 0.0 2.2e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain TPP_enzyme_N PF02776.13 KXX79063.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF4191 PF13829.1 KXX79063.1 - 0.058 12.4 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF742 PF05331.6 KXX79063.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TFR_dimer PF04253.10 KXX79063.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Adenylsucc_synt PF00709.16 KXX79064.1 - 9.1e-152 505.5 0.0 1e-151 505.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1811 PF08838.5 KXX79064.1 - 0.12 12.2 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) ELO PF01151.13 KXX79065.1 - 4.4e-81 271.8 11.4 5.6e-81 271.5 7.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UPF0444 PF15475.1 KXX79065.1 - 0.011 15.7 1.7 0.027 14.5 1.2 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 PH PF00169.24 KXX79066.1 - 0.0017 18.5 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 KXX79066.1 - 0.2 11.2 0.0 0.49 9.9 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Adap_comp_sub PF00928.16 KXX79068.1 - 4e-19 68.7 0.1 6e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KXX79068.1 - 1.5e-07 31.1 0.1 2.5e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Apc4 PF12896.2 KXX79069.1 - 6e-62 208.6 0.1 9e-62 208.0 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 FAD_binding_4 PF01565.18 KXX79070.1 - 1.1e-26 92.9 0.1 2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KXX79070.1 - 1.8e-22 79.9 0.5 3.9e-22 78.7 0.2 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain GnsAB PF08178.6 KXX79070.1 - 0.033 13.8 0.1 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB family SET PF00856.23 KXX79072.1 - 9.3e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 SET domain p450 PF00067.17 KXX79074.1 - 3.1e-23 82.0 0.0 3.8e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.23 KXX79075.1 - 3e-09 36.5 2.9 6.9e-09 35.3 2.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KXX79075.1 - 5.5e-06 26.2 0.0 1.1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 KXX79076.1 - 2.5e-13 49.4 0.0 1.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX79076.1 - 5.7e-11 42.2 0.0 1.8e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79076.1 - 1.1e-06 28.4 0.0 0.00015 21.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.26 KXX79077.1 - 8.2e-16 57.6 0.0 2.6e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3074 PF11274.3 KXX79078.1 - 3.6e-60 202.7 5.0 3.9e-58 196.1 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.14 KXX79078.1 - 0.0025 17.1 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 START domain Mg_trans_NIPA PF05653.9 KXX79080.1 - 1.9e-98 329.1 12.0 2.5e-98 328.7 8.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KXX79080.1 - 7.9e-09 35.7 2.1 7.9e-09 35.7 1.5 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KXX79080.1 - 0.0002 21.3 9.1 0.0002 21.3 6.3 3.0 2 1 1 3 3 3 2 EamA-like transporter family DUF1282 PF06930.7 KXX79080.1 - 1.5 8.4 16.9 3.4 7.3 4.5 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) DUF1295 PF06966.7 KXX79081.1 - 1.3e-32 113.0 0.0 1.4e-31 109.5 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KXX79081.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KXX79081.1 - 0.00018 21.5 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KXX79081.1 - 0.0042 15.6 0.0 0.0062 15.1 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KXX79081.1 - 0.0079 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Prenyltrans_2 PF13249.1 KXX79082.1 - 1.4e-07 31.9 0.1 0.14 12.5 0.0 4.6 4 1 0 4 4 4 2 Prenyltransferase-like FAM150 PF15129.1 KXX79082.1 - 0.15 11.9 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 FAM150 family GST_C PF00043.20 KXX79083.1 - 4.2e-13 49.1 0.0 6.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX79083.1 - 5.9e-13 48.7 0.0 3e-12 46.5 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX79083.1 - 1.4e-09 37.8 0.0 3.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX79083.1 - 5.9e-09 36.0 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX79083.1 - 2.3e-08 33.8 0.1 3.8e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX79083.1 - 1.9e-07 31.4 0.2 3.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KXX79084.1 - 9.8e-39 133.0 53.8 9.8e-39 133.0 37.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.6 KXX79084.1 - 0.22 11.0 2.6 0.41 10.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Methyltransf_23 PF13489.1 KXX79085.1 - 5.3e-18 65.2 0.0 8.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79085.1 - 2.1e-10 40.9 0.0 4.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79085.1 - 3.5e-07 29.9 0.0 4.9e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79085.1 - 3.1e-06 27.5 0.0 1.7e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79085.1 - 5.1e-06 27.0 0.0 6.9e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79085.1 - 7.1e-05 22.0 0.0 0.00077 18.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX79085.1 - 8.1e-05 22.9 0.0 0.00034 20.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX79085.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KXX79085.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 KXX79085.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KXX79085.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PDE6_gamma PF04868.7 KXX79085.1 - 1.6 8.6 4.0 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Hydrolase_6 PF13344.1 KXX79087.1 - 5e-21 74.4 0.0 9.8e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX79087.1 - 1e-17 63.6 0.0 2.7e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KXX79087.1 - 0.0005 20.3 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX79087.1 - 0.0045 17.4 0.0 0.038 14.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 KXX79088.1 - 9.7e-60 201.7 0.0 1.1e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.1 KXX79089.1 - 7.3e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX79089.1 - 3e-15 55.9 0.0 5.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX79089.1 - 1.6e-07 31.1 2.0 3e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX79089.1 - 9.2e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX79089.1 - 0.0002 21.4 0.0 0.00073 19.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RIC1 PF07064.8 KXX79090.1 - 3.1e-90 302.1 0.1 4.3e-90 301.6 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KXX79090.1 - 5.3e-05 22.9 1.8 0.29 11.0 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.7 KXX79090.1 - 0.098 12.3 0.3 0.95 9.2 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 KXX79091.1 - 1e-28 98.1 5.7 1.5e-07 30.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KXX79091.1 - 5e-05 21.6 0.6 0.00074 17.7 0.0 2.6 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KXX79091.1 - 0.0069 15.8 0.1 0.14 11.6 0.0 2.3 1 1 2 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 KXX79091.1 - 0.017 13.4 0.0 1 7.5 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain DUF1513 PF07433.6 KXX79091.1 - 0.02 13.7 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF3312 PF11768.3 KXX79091.1 - 0.035 12.3 0.0 0.11 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Fungal_trans PF04082.13 KXX79092.1 - 1.3e-18 66.8 0.0 3.4e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79092.1 - 2e-08 33.9 8.7 2e-08 33.9 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hep_59 PF07052.6 KXX79093.1 - 1.8e-18 66.8 2.1 1.8e-18 66.8 1.4 2.8 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DMAP_binding PF06464.6 KXX79093.1 - 0.032 14.8 0.3 0.032 14.8 0.2 3.1 3 0 0 3 3 3 0 DMAP1-binding Domain SKG6 PF08693.5 KXX79094.1 - 0.0038 16.5 1.7 0.008 15.4 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KXX79094.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 KXX79094.1 - 0.031 12.5 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lamp PF01299.12 KXX79094.1 - 4.2 6.4 5.8 2 7.4 0.3 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Got1 PF04178.7 KXX79095.1 - 3.8e-30 104.4 15.8 5e-30 104.0 10.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KXX79095.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 NfeD PF01957.13 KXX79095.1 - 0.22 11.6 3.2 0.21 11.7 1.4 1.5 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding HLH PF00010.21 KXX79096.1 - 2.2e-12 46.4 0.0 6.6e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 KXX79096.1 - 0.021 15.2 1.7 0.52 10.7 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPR3 PF03666.8 KXX79097.1 - 5.2e-151 503.2 0.0 7e-151 502.8 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SecA_PP_bind PF01043.15 KXX79097.1 - 0.091 13.1 0.2 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Choline_kinase PF01633.15 KXX79098.1 - 3.7e-55 186.7 0.0 3.3e-54 183.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KXX79098.1 - 9.7e-12 45.1 1.6 2.9e-11 43.5 1.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KXX79098.1 - 0.0092 15.1 0.0 0.12 11.5 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase WD40 PF00400.27 KXX79099.1 - 1.3e-25 88.3 11.3 2.8e-07 30.1 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KXX79099.1 - 0.00023 19.4 0.1 0.0011 17.2 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX79099.1 - 0.00047 19.0 0.1 1 7.9 0.0 3.3 1 1 3 4 4 4 2 Nup133 N terminal like Cyclin_N PF00134.18 KXX79099.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Dicty_REP PF05086.7 KXX79100.1 - 3.5 5.2 5.0 5.3 4.6 3.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HpcH_HpaI PF03328.9 KXX79101.1 - 9.9e-39 132.4 0.0 1.8e-38 131.6 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KXX79101.1 - 1.5e-05 23.9 0.0 4.8e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold HTH_29 PF13551.1 KXX79102.1 - 4.4e-07 30.0 0.2 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KXX79102.1 - 3.1e-05 23.4 1.4 0.00032 20.2 0.2 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 KXX79102.1 - 0.011 15.2 0.3 0.072 12.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.1 KXX79102.1 - 0.025 15.3 2.8 0.074 13.8 0.0 3.0 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KXX79102.1 - 0.042 13.9 0.1 0.43 10.6 0.0 2.6 2 1 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.1 KXX79102.1 - 0.09 12.3 0.2 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.15 KXX79102.1 - 0.14 11.8 0.0 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Sugar_tr PF00083.19 KXX79103.1 - 1.2e-30 106.4 31.8 1.7e-19 69.7 5.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX79103.1 - 3.8e-23 81.7 24.1 2.2e-17 62.7 8.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Acetate_kinase PF00871.12 KXX79104.1 - 2.1e-86 289.8 0.0 2.6e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1908 PF08926.6 KXX79105.1 - 0.056 12.2 0.8 0.081 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Corona_nucleoca PF00937.13 KXX79106.1 - 0.0075 15.2 7.4 0.0075 15.2 5.1 4.5 4 1 0 5 5 5 2 Coronavirus nucleocapsid protein DUF1908 PF08926.6 KXX79106.1 - 3.4 6.3 6.8 2.4 6.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) zf-C2H2_4 PF13894.1 KXX79107.1 - 1.7e-05 24.8 7.6 0.0013 18.9 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX79107.1 - 0.00032 20.8 11.1 0.0065 16.7 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX79107.1 - 0.0052 17.0 2.3 0.0052 17.0 1.6 2.9 3 0 0 3 3 3 1 Zinc-finger double domain DUF3439 PF11921.3 KXX79107.1 - 0.06 13.1 2.6 0.13 12.0 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S15 PF00312.17 KXX79107.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 zf-met PF12874.2 KXX79107.1 - 0.44 10.8 5.3 7.9 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KXX79107.1 - 0.79 10.1 4.4 2.2 8.6 0.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger AAA PF00004.24 KXX79109.1 - 2.7e-29 102.0 0.0 1.5e-10 41.3 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KXX79109.1 - 1.1e-09 38.1 0.0 0.0051 16.3 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KXX79109.1 - 1.4e-08 34.9 2.4 0.1 12.7 0.1 5.5 3 3 1 4 4 4 2 AAA domain AAA_17 PF13207.1 KXX79109.1 - 8.8e-08 32.9 3.6 0.00038 21.2 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KXX79109.1 - 1.1e-07 31.5 0.2 0.083 12.6 0.0 4.2 4 0 0 4 4 3 2 Part of AAA domain Mg_chelatase PF01078.16 KXX79109.1 - 4e-07 29.3 0.0 0.14 11.2 0.0 3.9 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX79109.1 - 9.8e-07 28.5 0.1 0.1 12.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KXX79109.1 - 1.7e-06 27.9 0.0 0.025 14.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX79109.1 - 6.7e-05 22.9 0.0 0.24 11.3 0.0 3.4 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.1 KXX79109.1 - 7.6e-05 22.3 1.0 0.26 10.8 0.0 4.3 3 2 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KXX79109.1 - 0.00014 21.4 1.9 0.19 11.1 0.0 3.7 3 1 1 4 4 4 1 AAA-like domain RuvB_N PF05496.7 KXX79109.1 - 0.00022 20.3 2.1 3.1 6.7 0.0 4.3 5 1 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KXX79109.1 - 0.00027 20.9 0.2 1.2 9.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 KXX79109.1 - 0.0017 17.8 0.1 9.5 5.5 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.1 KXX79109.1 - 0.002 18.4 8.5 0.17 12.1 0.1 3.7 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 KXX79109.1 - 0.02 15.0 0.1 8.4 6.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Torsin PF06309.6 KXX79109.1 - 0.027 14.3 0.1 18 5.2 0.0 3.5 3 0 0 3 3 3 0 Torsin SRP54 PF00448.17 KXX79109.1 - 0.044 13.2 1.5 3.7 6.9 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 KXX79109.1 - 0.059 12.9 11.0 11 5.4 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.1 KXX79109.1 - 0.53 9.8 7.0 7.2 6.1 1.3 3.1 2 1 0 2 2 2 0 AAA domain La PF05383.12 KXX79110.1 - 1.2e-16 60.2 0.0 2.1e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 La domain Wound_ind PF08186.6 KXX79110.1 - 7.5 6.5 7.4 1.6 8.6 0.9 3.0 3 0 0 3 3 3 0 Wound-inducible basic protein family HLH PF00010.21 KXX79111.1 - 7.5e-07 28.7 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 KXX79111.1 - 0.009 16.4 0.2 0.031 14.7 0.0 1.9 2 0 0 2 2 2 1 Vascular protein family Vasculin-like 1 GCV_T PF01571.16 KXX79112.1 - 2.2e-63 213.4 0.0 2.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KXX79112.1 - 1.6e-19 69.7 0.3 3.2e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HA2 PF04408.18 KXX79113.1 - 3.9e-26 91.0 0.0 1.2e-25 89.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KXX79113.1 - 6.3e-24 83.9 0.0 7.2e-23 80.5 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KXX79113.1 - 1.1e-12 47.6 0.0 2.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX79113.1 - 7.4e-08 32.0 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX79113.1 - 0.0001 22.4 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KXX79113.1 - 0.0011 18.8 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KXX79113.1 - 0.0017 17.4 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KXX79113.1 - 0.0018 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KXX79113.1 - 0.0031 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KXX79113.1 - 0.0036 17.0 0.1 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.1 KXX79113.1 - 0.0057 16.2 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KXX79113.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 KXX79113.1 - 0.026 14.4 0.3 0.2 11.5 0.1 2.4 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KXX79113.1 - 0.059 12.7 0.2 8.9 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KXX79113.1 - 0.099 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KXX79113.1 - 0.11 12.8 0.2 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Pam16 PF03656.8 KXX79113.1 - 1.5 8.6 5.9 0.25 11.1 0.9 2.1 2 0 0 2 2 2 0 Pam16 EF-hand_1 PF00036.27 KXX79114.1 - 7.8e-27 90.5 7.7 1e-06 27.5 0.1 5.5 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KXX79114.1 - 5.1e-26 90.6 3.8 4.5e-10 39.5 0.6 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KXX79114.1 - 1e-21 74.8 8.0 0.00022 20.8 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KXX79114.1 - 1.1e-20 72.9 11.9 1.1e-08 34.5 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KXX79114.1 - 1.8e-17 61.7 9.6 0.00035 19.7 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KXX79114.1 - 0.081 12.8 0.3 1 9.3 0.0 2.7 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 KXX79114.1 - 0.12 12.0 0.1 17 5.2 0.0 3.0 2 1 1 3 3 3 0 EF hand RRM_1 PF00076.17 KXX79115.1 - 1.1e-24 85.8 0.1 1.4e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX79115.1 - 2.3e-17 62.7 0.0 3.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79115.1 - 2.7e-11 43.1 0.0 4.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX79115.1 - 0.038 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif DUF1877 PF08974.5 KXX79115.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) DUF846 PF05832.7 KXX79116.1 - 1.9e-53 179.9 8.6 2.2e-53 179.7 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 KXX79116.1 - 0.035 14.1 7.0 0.27 11.3 0.3 2.1 2 0 0 2 2 2 0 YwiC-like protein ABC2_membrane_3 PF12698.2 KXX79116.1 - 1.2 8.0 13.3 0.024 13.6 2.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4191 PF13829.1 KXX79116.1 - 3.2 6.8 8.7 5 6.1 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) ChaC PF04752.7 KXX79117.1 - 5.4e-53 179.5 0.0 6.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Serine_rich PF08824.5 KXX79118.1 - 0.015 14.9 0.4 0.022 14.5 0.3 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain MxiH PF09392.5 KXX79118.1 - 2 9.0 6.4 3.5 8.2 4.4 1.4 1 0 0 1 1 1 0 Type III secretion needle MxiH like TFIIS_C PF01096.13 KXX79119.1 - 4.8e-10 38.9 6.9 4.8e-10 38.9 4.8 4.8 4 2 1 5 5 5 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KXX79119.1 - 2.9e-09 36.4 4.9 2.9e-09 36.4 3.4 3.4 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit FYVE PF01363.16 KXX79119.1 - 0.13 12.2 14.0 1.3 8.9 0.7 3.1 2 1 0 2 2 2 0 FYVE zinc finger eIF3g PF12353.3 KXX79119.1 - 1.5 8.7 5.5 0.17 11.7 0.2 2.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-TFIIIC PF12660.2 KXX79119.1 - 2 8.3 10.1 2 8.3 0.6 3.0 3 0 0 3 3 3 0 Putative zinc-finger of transcription factor IIIC complex zf-CHY PF05495.7 KXX79119.1 - 6 7.0 18.1 0.18 11.9 0.8 3.5 4 0 0 4 4 4 0 CHY zinc finger Rotamase PF00639.16 KXX79120.1 - 1.3e-20 73.9 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KXX79120.1 - 1.2e-15 57.8 0.0 1.6e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KXX79120.1 - 1.2e-07 31.3 0.6 2.4e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 KXX79120.1 - 4.1e-05 24.2 0.0 5.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 KXX79120.1 - 0.022 14.5 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 MAM domain SET PF00856.23 KXX79121.1 - 1.3e-08 35.2 0.3 8.2e-08 32.7 0.0 2.3 2 1 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 KXX79122.1 - 1.5e-40 137.7 2.1 1.7e-40 137.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Adeno_E1B_19K PF01691.11 KXX79124.1 - 0.15 11.3 0.8 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen DUF418 PF04235.7 KXX79124.1 - 0.73 9.4 9.4 0.91 9.1 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF418) LrgB PF04172.11 KXX79125.1 - 3.2e-10 39.5 12.4 3.2e-10 39.5 8.6 1.8 2 0 0 2 2 2 1 LrgB-like family NMO PF03060.10 KXX79125.1 - 0.02 14.0 0.3 0.03 13.4 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF486 PF04342.7 KXX79125.1 - 0.031 14.3 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF486 CVNH PF08881.5 KXX79126.1 - 1.9e-12 47.2 0.0 2.5e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.19 KXX79127.1 - 4.4e-27 95.1 17.4 7.1e-27 94.4 12.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KXX79127.1 - 7.6e-09 35.6 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Acetyltransf_3 PF13302.1 KXX79128.1 - 8e-32 110.3 0.0 9.6e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KXX79128.1 - 2.6e-07 30.7 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX79128.1 - 3e-06 27.1 0.0 7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX79128.1 - 2.3e-05 24.3 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GMC_oxred_N PF00732.14 KXX79129.1 - 9.1e-69 231.8 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79129.1 - 4.5e-29 101.5 0.0 8.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX79129.1 - 5.1e-06 25.6 0.2 0.00053 18.9 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX79129.1 - 0.00064 18.6 0.1 0.46 9.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KXX79129.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX79129.1 - 0.0092 14.9 0.1 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KXX79129.1 - 0.056 12.5 1.5 0.14 11.2 0.1 2.1 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.27 KXX79130.1 - 1.3e-53 177.0 22.3 1e-09 37.8 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KXX79130.1 - 1.5e-10 40.6 0.4 6.6e-10 38.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KXX79130.1 - 1.2e-08 34.3 0.1 4.8e-08 32.4 0.0 2.1 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KXX79130.1 - 2.5e-07 29.2 3.0 0.3 9.1 0.0 4.1 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Mito_carr PF00153.22 KXX79131.1 - 2.1e-70 232.4 1.8 3.3e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_2 PF13923.1 KXX79132.1 - 3.6e-08 33.2 1.6 3.6e-08 33.2 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX79132.1 - 2.1e-07 30.6 5.6 5.3e-07 29.3 3.9 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX79132.1 - 2.5e-05 23.8 3.8 2.5e-05 23.8 2.7 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX79132.1 - 5.3e-05 22.8 3.1 6.5e-05 22.5 1.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX79132.1 - 0.00017 21.6 1.9 0.00017 21.6 1.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KXX79132.1 - 0.00061 19.4 3.6 0.00061 19.4 2.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KXX79132.1 - 0.0087 15.7 4.0 0.054 13.2 0.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KXX79132.1 - 0.042 13.7 0.6 0.042 13.7 0.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KXX79132.1 - 0.099 12.4 0.6 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 KXX79132.1 - 0.2 11.3 2.1 0.3 10.8 1.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING-like PF08746.6 KXX79132.1 - 4.5 7.3 8.1 2 8.4 1.7 2.4 2 0 0 2 2 2 0 RING-like domain F-box-like PF12937.2 KXX79133.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like Acyl_transf_3 PF01757.17 KXX79134.1 - 4.1e-22 78.4 21.5 1.2e-21 76.8 14.6 2.0 1 1 1 2 2 2 1 Acyltransferase family ACC_central PF08326.7 KXX79135.1 - 5.8e-251 834.5 0.0 7.2e-251 834.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KXX79135.1 - 1.2e-176 587.9 0.0 1.6e-176 587.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KXX79135.1 - 7.5e-53 178.9 0.0 1.3e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KXX79135.1 - 1.3e-23 83.1 0.1 3e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KXX79135.1 - 2.1e-20 72.6 0.0 2.8e-18 65.8 0.0 3.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KXX79135.1 - 7.9e-16 57.4 0.1 1.6e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KXX79135.1 - 1.7e-11 44.2 0.0 4.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KXX79135.1 - 1.8e-08 33.5 0.0 8.5e-06 24.7 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX79135.1 - 5.3e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KXX79135.1 - 0.0035 16.7 0.0 0.0084 15.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KXX79135.1 - 0.0047 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KXX79135.1 - 0.019 14.6 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like NUDE_C PF04880.8 KXX79136.1 - 5.9e-22 78.7 4.6 5.9e-22 78.7 3.2 4.0 1 1 2 3 3 1 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KXX79136.1 - 0.0022 18.2 7.7 0.0022 18.2 5.3 3.6 1 1 2 3 3 2 1 Protein of unknown function (DUF904) IncA PF04156.9 KXX79136.1 - 0.0029 17.2 28.7 0.035 13.6 12.8 2.4 1 1 1 2 2 2 2 IncA protein WEMBL PF05701.6 KXX79136.1 - 0.017 13.6 26.4 0.025 13.0 18.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ERM PF00769.14 KXX79136.1 - 0.046 13.2 23.2 0.014 14.9 7.5 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 KXX79136.1 - 0.079 12.4 27.9 0.79 9.1 7.7 2.5 2 1 1 3 3 3 0 Intermediate filament protein Chibby PF14645.1 KXX79136.1 - 0.14 12.0 11.4 0.21 11.4 0.7 2.6 1 1 1 2 2 2 0 Chibby family Tropomyosin_1 PF12718.2 KXX79136.1 - 2.2 8.1 35.0 53 3.6 14.9 3.9 2 1 1 3 3 3 0 Tropomyosin like IFT57 PF10498.4 KXX79136.1 - 4.7 5.8 18.0 0.21 10.2 5.4 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 KXX79136.1 - 5.8 6.7 35.1 0.88 9.4 10.6 3.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KXX79136.1 - 6.7 3.9 22.7 9.7 3.3 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 KXX79136.1 - 7.6 6.3 28.0 23 4.7 12.1 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) BTB PF00651.26 KXX79137.1 - 0.002 18.1 0.0 0.0066 16.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain HAUS-augmin3 PF14932.1 KXX79141.1 - 0.097 11.8 20.3 0.055 12.6 7.0 3.8 2 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.6 KXX79141.1 - 0.2 11.5 8.7 0.38 10.6 0.5 4.0 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 KXX79141.1 - 2.3 8.3 8.5 9.1 6.3 0.1 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family STAT_alpha PF01017.15 KXX79141.1 - 2.6 7.7 14.2 0.38 10.4 3.9 3.5 3 1 1 4 4 4 0 STAT protein, all-alpha domain DUF1319 PF07028.6 KXX79141.1 - 4.4 7.5 14.4 1.3 9.2 0.3 4.0 5 1 0 5 5 5 0 Protein of unknown function (DUF1319) Glyco_hydro_76 PF03663.9 KXX79143.1 - 7e-143 476.4 2.1 9e-143 476.1 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NPV_P10 PF05531.7 KXX79144.1 - 7.8e-06 26.0 10.7 0.0088 16.2 0.0 4.8 2 1 2 4 4 4 1 Nucleopolyhedrovirus P10 protein Matrilin_ccoil PF10393.4 KXX79144.1 - 0.0019 17.4 4.9 0.91 8.9 0.0 4.0 4 0 0 4 4 4 2 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.7 KXX79144.1 - 0.0055 17.0 22.0 2.3 8.6 0.6 6.0 2 1 4 6 6 6 2 SlyX ArsR PF09824.4 KXX79144.1 - 0.016 14.5 2.2 0.19 11.0 0.2 2.5 1 1 1 2 2 2 0 ArsR transcriptional regulator Reo_sigmaC PF04582.7 KXX79144.1 - 0.035 13.3 16.8 0.12 11.4 3.1 3.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein LXG PF04740.7 KXX79144.1 - 0.039 13.7 12.8 0.018 14.8 3.2 3.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF1664 PF07889.7 KXX79144.1 - 0.11 12.3 19.6 1.1 9.0 0.6 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KXX79144.1 - 0.13 12.2 18.5 0.055 13.3 0.9 5.5 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 KXX79144.1 - 0.26 10.6 6.0 1.5 8.1 1.5 3.2 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AKNA PF12443.3 KXX79144.1 - 0.27 11.2 8.6 0.37 10.8 0.2 3.4 1 1 2 3 3 3 0 AT-hook-containing transcription factor Occludin_ELL PF07303.8 KXX79144.1 - 0.3 11.8 15.2 4.9 7.9 0.1 4.4 1 1 2 4 4 4 0 Occludin homology domain LPP PF04728.8 KXX79144.1 - 0.41 10.4 4.8 1.8 8.4 0.6 3.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper FliD_C PF07195.7 KXX79144.1 - 0.63 9.2 13.4 0.75 9.0 0.9 4.0 2 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Snapin_Pallidin PF14712.1 KXX79144.1 - 0.84 9.9 19.4 1.4 9.2 1.1 5.7 3 2 1 5 5 5 0 Snapin/Pallidin GP41 PF00517.12 KXX79144.1 - 0.94 9.0 4.9 11 5.4 0.2 3.4 2 1 1 3 3 3 0 Retroviral envelope protein APG6 PF04111.7 KXX79144.1 - 1.1 8.2 21.1 0.2 10.6 3.9 2.6 1 1 0 2 2 2 0 Autophagy protein Apg6 HalX PF08663.5 KXX79144.1 - 1.2 9.2 8.4 3.8 7.5 0.1 4.2 3 2 1 4 4 3 0 HalX domain FliJ PF02050.11 KXX79144.1 - 1.9 8.5 19.0 1.4 8.9 2.4 4.0 1 1 3 4 4 4 0 Flagellar FliJ protein BLOC1_2 PF10046.4 KXX79144.1 - 2 8.5 11.8 38 4.5 0.0 4.6 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filo_VP35 PF02097.10 KXX79144.1 - 2.7 7.1 12.1 4.8 6.2 2.9 3.4 1 1 3 4 4 4 0 Filoviridae VP35 MtrG PF04210.8 KXX79144.1 - 3.2 7.4 5.8 38 4.0 0.1 4.1 5 0 0 5 5 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G FUSC PF04632.7 KXX79144.1 - 3.5 5.9 15.7 0.76 8.1 6.0 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family Laminin_II PF06009.7 KXX79144.1 - 4.2 7.1 25.1 1.7 8.4 3.8 4.5 2 1 2 4 4 4 0 Laminin Domain II TBPIP PF07106.8 KXX79144.1 - 5.3 6.5 25.1 2.1 7.8 3.1 4.5 1 1 4 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Noelin-1 PF12308.3 KXX79144.1 - 5.7 6.7 14.4 0.38 10.5 0.1 3.7 3 1 0 4 4 3 0 Neurogenesis glycoprotein RabGAP-TBC PF00566.13 KXX79146.1 - 4.7e-30 104.6 0.0 6.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF604 PF04646.7 KXX79147.1 - 1.5e-10 40.7 0.0 2.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 KXX79147.1 - 0.0019 17.4 0.0 0.0054 15.9 0.0 1.6 1 1 0 1 1 1 1 Fringe-like Fungal_trans PF04082.13 KXX79148.1 - 1.1e-12 47.3 0.0 1.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79148.1 - 5.5e-06 26.1 8.9 9.9e-06 25.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_24 PF13578.1 KXX79149.1 - 5.1e-13 49.7 0.0 8.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KXX79149.1 - 2e-11 43.3 0.0 3.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KXX79149.1 - 2.6e-05 24.7 0.0 4.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NatB_MDM20 PF09797.4 KXX79150.1 - 3.3e-85 285.9 0.0 5.4e-85 285.2 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TENA_THI-4 PF03070.11 KXX79150.1 - 0.13 11.9 0.1 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 TENA/THI-4/PQQC family Ilm1 PF10311.4 KXX79151.1 - 8.6e-59 197.7 0.2 1e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 G-patch PF01585.18 KXX79152.1 - 1.2e-07 31.3 0.1 2.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Remorin_N PF03766.8 KXX79152.1 - 0.031 14.0 0.6 0.094 12.5 0.4 1.9 1 0 0 1 1 1 0 Remorin, N-terminal region Ras PF00071.17 KXX79153.1 - 3.4e-65 218.3 0.0 4.4e-65 217.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX79153.1 - 1.4e-19 70.7 0.0 2.1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX79153.1 - 4e-13 48.9 0.0 4.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX79153.1 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KXX79153.1 - 7.9e-06 25.1 0.0 8.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KXX79153.1 - 0.0042 17.0 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX79153.1 - 0.015 14.5 0.0 0.073 12.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 KXX79153.1 - 0.021 14.0 0.0 0.065 12.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KXX79153.1 - 0.025 13.7 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 KXX79153.1 - 0.091 12.3 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX79153.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 KXX79153.1 - 0.15 10.6 0.4 16 4.0 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Strumpellin PF10266.4 KXX79153.1 - 0.18 9.1 0.0 0.22 8.9 0.0 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Sec63 PF02889.11 KXX79154.1 - 2.8e-149 496.5 0.0 8.8e-95 317.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KXX79154.1 - 1.1e-52 177.9 0.1 3.7e-28 98.1 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX79154.1 - 3.3e-17 62.0 0.0 1.1e-06 28.4 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KXX79154.1 - 7.8e-15 55.1 0.0 4.8e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX79154.1 - 2.6e-07 30.8 0.1 0.037 14.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KXX79154.1 - 4e-07 29.6 0.3 0.024 14.3 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 KXX79154.1 - 1.9e-05 23.6 0.1 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_30 PF13604.1 KXX79154.1 - 6.8e-05 22.5 0.0 0.06 12.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KXX79154.1 - 0.00046 20.4 0.1 2.6 8.2 0.0 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX79154.1 - 0.0025 17.2 0.2 0.28 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KXX79154.1 - 0.018 14.4 0.1 15 4.9 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KXX79154.1 - 0.047 12.7 0.1 1.4 8.0 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin FA_hydroxylase PF04116.8 KXX79155.1 - 2.9e-16 59.8 16.6 2.9e-16 59.8 11.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.5 KXX79156.1 - 9.4e-90 300.4 0.0 1.5e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 bZIP_1 PF00170.16 KXX79157.1 - 3.4e-08 33.3 7.8 1.4e-07 31.3 5.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX79157.1 - 0.63 9.8 9.3 26 4.7 6.5 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Pterin_4a PF01329.14 KXX79158.1 - 5.1e-27 93.4 0.2 6.6e-27 93.1 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DASH_Dad4 PF08650.5 KXX79159.1 - 6.6e-23 80.4 5.5 6.8e-23 80.3 3.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KXX79159.1 - 0.036 14.0 0.4 0.039 13.8 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 KXX79159.1 - 0.046 13.4 3.7 0.058 13.0 2.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Biotin_carb_C PF02785.14 KXX79159.1 - 0.096 12.6 0.1 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Pecanex_C PF05041.10 KXX79159.1 - 0.12 11.4 0.9 0.14 11.1 0.7 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) V-SNARE_C PF12352.3 KXX79159.1 - 0.23 11.5 1.9 0.35 10.9 0.7 1.6 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Actin PF00022.14 KXX79160.1 - 1.5e-56 191.5 0.0 6.2e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Actin IR1-M PF12185.3 KXX79160.1 - 0.011 15.4 0.6 0.039 13.6 0.4 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain adh_short PF00106.20 KXX79161.1 - 1.3e-31 109.8 0.2 1.6e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX79161.1 - 1.4e-13 50.9 0.1 1.9e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX79161.1 - 5.7e-07 29.5 0.0 7.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX79161.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX79161.1 - 0.037 13.8 0.2 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1182 PF06681.8 KXX79161.1 - 0.073 12.2 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF2717 PF10911.3 KXX79161.1 - 0.15 11.5 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) FSH1 PF03959.8 KXX79162.1 - 1.4e-32 112.8 0.0 1.8e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KXX79162.1 - 3.3e-07 29.9 0.0 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX79162.1 - 5.3e-06 26.4 2.4 0.00012 22.0 1.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79162.1 - 0.00018 21.3 0.0 0.0003 20.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX79162.1 - 0.038 13.5 0.2 0.083 12.4 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KXX79163.1 - 1.5e-34 119.2 46.5 1.5e-34 119.2 32.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX79163.1 - 1.6e-08 33.5 21.1 4.9e-08 31.9 14.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Ion_trans PF00520.26 KXX79166.1 - 5.3e-05 22.5 23.8 0.00046 19.4 15.4 2.4 1 1 0 1 1 1 1 Ion transport protein DUF3671 PF12420.3 KXX79166.1 - 6.3 6.8 9.4 14 5.7 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function CPSase_L_D2 PF02786.12 KXX79167.1 - 1e-106 354.9 0.2 4.9e-84 280.8 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KXX79167.1 - 3.3e-44 149.5 0.0 7.4e-44 148.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KXX79167.1 - 1.2e-43 148.8 0.0 2.1e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KXX79167.1 - 5.6e-41 139.5 0.0 1.2e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KXX79167.1 - 6.3e-41 138.9 0.0 3.6e-20 72.0 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KXX79167.1 - 1.6e-40 137.6 0.0 4.5e-40 136.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KXX79167.1 - 5.7e-31 107.6 0.2 2.7e-17 63.0 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KXX79167.1 - 3.3e-26 92.0 0.0 8.6e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 KXX79167.1 - 9.2e-21 73.5 0.0 4.4e-20 71.4 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 KXX79167.1 - 1.6e-16 59.9 0.1 6.2e-06 25.1 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX79167.1 - 6.1e-14 51.8 0.3 5.4e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KXX79167.1 - 8.5e-14 51.2 0.1 4.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KXX79167.1 - 5.6e-06 25.9 0.3 0.00021 20.7 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 KXX79167.1 - 0.00026 20.5 0.1 1 8.8 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 KXX79167.1 - 0.0019 18.0 0.5 0.43 10.4 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain DJ-1_PfpI PF01965.19 KXX79167.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Transferase PF02458.10 KXX79168.1 - 1.5e-17 63.1 0.0 2.7e-17 62.3 0.0 1.3 2 0 0 2 2 2 1 Transferase family Condensation PF00668.15 KXX79169.1 - 0.12 11.2 0.0 0.71 8.6 0.0 2.1 2 0 0 2 2 2 0 Condensation domain FAD_binding_4 PF01565.18 KXX79170.1 - 1.2e-28 99.3 1.7 1.8e-28 98.7 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX79170.1 - 5.7e-06 26.1 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KXX79171.1 - 1.8e-14 54.0 3.6 5.2e-14 52.5 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KXX79171.1 - 8.9e-08 31.9 0.4 2.4e-07 30.5 0.0 1.9 2 1 1 3 3 3 1 KR domain Epimerase PF01370.16 KXX79171.1 - 5.4e-07 29.2 0.0 9.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX79171.1 - 0.0009 18.9 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KXX79171.1 - 0.001 18.8 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX79171.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding E1-N PF14463.1 KXX79171.1 - 0.0032 17.0 0.1 0.0087 15.6 0.0 1.8 1 1 1 2 2 2 1 E1 N-terminal domain DAO PF01266.19 KXX79171.1 - 0.034 13.0 0.1 0.075 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ldh_1_N PF00056.18 KXX79171.1 - 0.077 12.8 0.0 13 5.6 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.11 KXX79171.1 - 0.095 12.1 0.5 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DUF3792 PF12670.2 KXX79171.1 - 0.33 10.8 2.5 0.28 11.0 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DsbB PF02600.11 KXX79172.1 - 0.089 12.5 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB Peptidase_C12 PF01088.16 KXX79174.1 - 9.4e-59 198.1 0.0 1.1e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.3 KXX79175.1 - 4.3e-16 58.0 2.0 5.9e-16 57.6 0.5 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KXX79175.1 - 2e-07 30.7 0.0 5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 KXX79175.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.16 KXX79176.1 - 8.7e-31 105.3 0.0 1.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KXX79176.1 - 6.5e-21 73.6 0.0 9.8e-21 73.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain TAP42 PF04177.7 KXX79178.1 - 1.4e-105 353.0 0.0 1.6e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family PNPOx_C PF10590.4 KXX79179.1 - 5.3e-21 73.8 2.7 3.6e-20 71.1 2.4 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KXX79179.1 - 1.8e-11 43.8 0.0 1.2e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KXX79179.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribonuclease_3 PF00636.21 KXX79180.1 - 9.7e-38 129.1 0.2 2.6e-18 66.5 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX79180.1 - 1.4e-21 76.7 0.0 8.8e-09 35.4 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KXX79180.1 - 3.6e-21 74.7 0.1 1e-19 70.1 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KXX79180.1 - 4.6e-13 48.8 0.1 1.1e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX79180.1 - 1.6e-10 41.0 0.0 3.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KXX79180.1 - 1.5e-09 37.6 0.0 3.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX79180.1 - 0.089 12.9 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF4360 PF14273.1 KXX79182.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4360) ketoacyl-synt PF00109.21 KXX79183.1 - 4.2e-70 236.1 0.5 1.3e-69 234.5 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX79183.1 - 1.8e-32 111.7 0.0 4.2e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KXX79183.1 - 7.2e-30 103.7 0.0 1.4e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 KXX79183.1 - 2.1e-24 86.4 0.0 5.3e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 KXX79183.1 - 2.3e-13 50.4 0.0 7.8e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX79183.1 - 4.2e-09 36.5 0.5 1e-08 35.3 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KXX79183.1 - 4.1e-08 33.0 0.0 1.4e-07 31.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KXX79183.1 - 1e-07 31.6 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KXX79183.1 - 1.6e-05 24.8 0.1 1.6e-05 24.8 0.0 2.1 2 0 0 2 2 1 1 short chain dehydrogenase Methyltransf_31 PF13847.1 KXX79183.1 - 2.4e-05 23.9 0.0 5.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KXX79183.1 - 4.6e-05 23.2 0.0 0.033 13.9 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 KXX79183.1 - 5.3e-05 23.6 0.0 0.00023 21.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 KXX79183.1 - 0.00013 21.0 0.1 0.00028 19.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 KXX79183.1 - 0.00023 20.8 1.1 0.00064 19.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Methyltransf_18 PF12847.2 KXX79183.1 - 0.0025 18.3 0.0 0.0095 16.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.12 KXX79183.1 - 0.0065 15.4 0.0 3 6.6 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 KXX79183.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 KXX79183.1 - 0.046 13.7 2.8 0.1 12.6 0.1 3.0 4 0 0 4 4 3 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX79183.1 - 0.081 11.8 0.0 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RrnaAD PF00398.15 KXX79183.1 - 0.18 10.8 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ATP_synt_H PF05493.8 KXX79184.1 - 2.5e-26 91.5 2.5 2.7e-26 91.3 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 KXX79184.1 - 0.016 14.5 1.4 0.017 14.5 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Git3 PF11710.3 KXX79184.1 - 0.04 13.4 0.1 0.043 13.3 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 YfhO PF09586.5 KXX79184.1 - 0.077 11.0 0.2 0.086 10.8 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_4 PF12730.2 KXX79184.1 - 0.12 11.4 5.2 0.16 11.1 3.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1129 PF06570.6 KXX79184.1 - 0.16 11.2 0.2 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 5TM-5TMR_LYT PF07694.7 KXX79184.1 - 0.27 10.5 2.2 0.29 10.4 1.5 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT OppC_N PF12911.2 KXX79184.1 - 0.51 9.7 3.1 0.47 9.8 0.8 1.8 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C NAD_binding_2 PF03446.10 KXX79185.1 - 8.9e-28 97.1 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KXX79185.1 - 6.3e-09 36.1 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KXX79185.1 - 3.9e-07 30.1 0.1 6.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KXX79185.1 - 3.7e-06 27.0 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KXX79185.1 - 0.014 15.4 0.3 0.034 14.1 0.2 1.7 1 1 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KXX79185.1 - 0.018 14.3 0.3 0.08 12.3 0.2 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ank_2 PF12796.2 KXX79186.1 - 1.8e-52 175.5 0.0 1.5e-20 73.3 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79186.1 - 2.9e-31 105.7 0.1 3.2e-06 26.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KXX79186.1 - 2.8e-27 94.5 0.5 2.5e-09 37.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79186.1 - 8.5e-23 78.1 0.0 0.0039 17.3 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KXX79186.1 - 2e-17 62.8 0.6 1.6e-05 25.0 0.0 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.7 KXX79186.1 - 1.9e-11 43.8 0.1 1.1e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX79186.1 - 2.1e-06 27.8 0.1 6.7e-06 26.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX79186.1 - 0.0026 17.9 0.0 0.0088 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF3767 PF12597.3 KXX79186.1 - 0.0064 16.1 0.1 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) KAP_NTPase PF07693.9 KXX79186.1 - 0.027 13.4 0.0 2.2 7.1 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Metallophos PF00149.23 KXX79187.1 - 3e-35 121.4 0.6 8.4e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ribonuclease_3 PF00636.21 KXX79188.1 - 2.9e-09 37.3 0.0 8.8e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX79188.1 - 1.7e-08 34.4 0.0 0.00051 19.9 0.1 2.3 1 1 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KXX79188.1 - 2.5e-05 24.7 0.0 4.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif YjbR PF04237.8 KXX79189.1 - 0.052 13.9 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 YjbR Septin PF00735.13 KXX79190.1 - 1.8e-121 404.5 0.2 1.8e-121 404.5 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KXX79190.1 - 5.5e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX79190.1 - 5.7e-05 22.6 0.9 0.00087 18.7 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KXX79190.1 - 9.4e-05 22.7 0.6 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KXX79190.1 - 0.00011 21.4 0.4 0.00074 18.7 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KXX79190.1 - 0.00047 19.6 0.0 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 KXX79190.1 - 0.0014 17.7 1.4 0.0027 16.8 0.0 2.0 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KXX79190.1 - 0.0032 17.4 0.1 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KXX79190.1 - 0.004 17.6 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KXX79190.1 - 0.0056 16.5 3.9 0.68 9.7 0.0 3.5 4 0 0 4 4 4 1 Dynamin family FtsK_SpoIIIE PF01580.13 KXX79190.1 - 0.0063 16.0 0.0 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KXX79190.1 - 0.0082 16.2 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 KXX79190.1 - 0.0096 15.3 0.7 0.044 13.1 0.0 2.3 3 0 0 3 3 2 1 Ras family AAA_29 PF13555.1 KXX79190.1 - 0.0096 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KXX79190.1 - 0.055 12.9 0.1 7.6 5.9 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KXX79190.1 - 0.12 11.9 0.6 0.2 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KXX79190.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KXX79190.1 - 0.14 12.3 0.4 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KXX79190.1 - 0.18 11.4 1.5 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 KXX79190.1 - 0.24 11.2 2.9 0.28 10.9 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 KXX79190.1 - 0.31 9.6 11.1 0.56 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.10 KXX79190.1 - 0.39 9.8 6.7 0.72 8.9 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KXX79190.1 - 1.4 8.5 8.1 2.2 7.8 5.6 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KXX79190.1 - 1.7 6.3 8.0 2.8 5.7 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PLA2_B PF01735.13 KXX79191.1 - 1.5e-25 89.3 0.0 3.5e-25 88.1 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain La PF05383.12 KXX79192.1 - 1.5e-16 59.9 0.0 3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KXX79192.1 - 5.3e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX79192.1 - 1.9e-06 27.4 0.4 5e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79192.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 KXX79193.1 - 1.8e-15 56.0 0.0 3.6e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KXX79193.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 S4 domain DUF2089 PF09862.4 KXX79193.1 - 0.099 12.4 0.1 5.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Cyclin_N PF00134.18 KXX79194.1 - 0.00045 19.7 0.1 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Zn_clus PF00172.13 KXX79196.1 - 0.021 14.7 2.1 0.041 13.7 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.11 KXX79197.1 - 1.1e-39 135.9 0.0 2.1e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KXX79197.1 - 6e-36 123.9 0.0 9.6e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KXX79197.1 - 2.4e-15 56.8 0.3 1e-14 54.7 0.0 2.2 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KXX79197.1 - 4.2e-09 35.6 1.4 9.9e-09 34.5 1.0 1.7 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 KXX79197.1 - 0.0028 17.7 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 KXX79197.1 - 0.0042 16.5 0.6 0.0042 16.5 0.4 2.1 2 1 0 2 2 2 1 HeH/LEM domain ZapA PF05164.8 KXX79197.1 - 0.0083 16.0 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein ZapA VWA PF00092.23 KXX79197.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Ferrochelatase PF00762.14 KXX79198.1 - 6.3e-93 311.2 0.0 7.4e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Zn_clus PF00172.13 KXX79199.1 - 1.8e-08 34.1 8.2 3.6e-08 33.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX79199.1 - 0.00059 18.5 0.5 0.001 17.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bcr-Abl_Oligo PF09036.5 KXX79199.1 - 0.088 12.7 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain RTA1 PF04479.8 KXX79200.1 - 6.9e-12 45.3 8.7 4.5e-11 42.6 6.0 2.0 1 1 0 1 1 1 1 RTA1 like protein SepZ PF06066.6 KXX79200.1 - 0.097 12.6 2.4 0.18 11.7 1.7 1.4 1 0 0 1 1 1 0 SepZ MFS_1 PF07690.11 KXX79201.1 - 1.1e-25 90.0 39.7 3.6e-20 71.9 11.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1751 PF08551.5 KXX79201.1 - 0.0011 19.3 2.3 0.0021 18.3 0.2 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) HIT PF01230.18 KXX79202.1 - 8e-20 71.1 0.0 1.2e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KXX79202.1 - 0.095 12.9 0.0 3.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Fungal_trans PF04082.13 KXX79203.1 - 3e-45 154.1 0.0 6.8e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79203.1 - 8e-09 35.2 6.6 1.7e-08 34.2 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR_2 PF10455.4 KXX79204.1 - 1.6e-58 197.8 0.2 2.5e-58 197.3 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KXX79204.1 - 3.9e-19 69.0 1.1 2e-18 66.7 0.7 1.9 1 1 0 1 1 1 1 BAR domain PPR_2 PF13041.1 KXX79204.1 - 7.4e-15 54.6 0.0 0.00038 20.3 0.0 5.2 5 0 0 5 5 5 3 PPR repeat family LSM PF01423.17 KXX79204.1 - 7.5e-15 54.2 0.0 1.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain PPR_3 PF13812.1 KXX79204.1 - 2.2e-12 46.2 1.9 0.0013 18.8 0.0 6.6 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 KXX79204.1 - 1.9e-10 39.9 0.9 0.17 11.9 0.0 4.7 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.2 KXX79204.1 - 0.0074 15.7 0.1 4.7 6.7 0.0 4.0 4 0 0 4 4 4 1 PPR repeat EIF4E-T PF10477.4 KXX79204.1 - 0.035 12.9 0.8 0.056 12.2 0.6 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF619 PF04768.8 KXX79205.1 - 1.3e-49 167.9 0.0 8.4e-49 165.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Trp_halogenase PF04820.9 KXX79206.1 - 2.6e-12 46.1 0.3 2.2e-11 43.0 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Amidohydro_2 PF04909.9 KXX79207.1 - 6.1e-28 98.1 0.8 7.5e-28 97.8 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase SGL PF08450.7 KXX79208.1 - 0.00041 19.8 0.0 0.0021 17.4 0.0 2.1 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NAD_binding_10 PF13460.1 KXX79209.1 - 3.1e-07 30.5 0.0 4.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX79209.1 - 0.0032 16.2 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX79209.1 - 0.011 14.6 0.0 1.9 7.3 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 KXX79209.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.17 KXX79210.1 - 1.1e-62 212.0 0.0 1.3e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KXX79211.1 - 2.8e-22 78.6 2.8 4.5e-22 78.0 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX79211.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Epsilon_antitox PF08998.6 KXX79213.1 - 4 7.4 7.2 0.91 9.5 0.7 2.3 1 1 1 2 2 2 0 Bacterial epsilon antitoxin ketoacyl-synt PF00109.21 KXX79217.1 - 6.6e-73 245.3 0.1 1.4e-72 244.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX79217.1 - 7.4e-36 122.6 0.9 1.6e-35 121.5 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KXX79217.1 - 8.8e-36 123.8 0.0 2.5e-30 105.9 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 KXX79217.1 - 5.3e-28 98.0 0.2 1.3e-27 96.7 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KXX79217.1 - 1.3e-16 60.6 6.0 2.1e-09 37.4 1.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 KXX79217.1 - 1.2e-12 47.9 0.1 6.9e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 KXX79217.1 - 1.2e-12 48.1 0.0 3.7e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KXX79217.1 - 3.5e-12 46.2 1.7 2.7e-09 36.9 0.0 3.8 3 1 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX79217.1 - 5.7e-09 36.1 8.8 1.9e-07 31.2 1.9 3.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 KXX79217.1 - 5.9e-09 35.6 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KXX79217.1 - 2e-08 33.7 0.0 1.4e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 KXX79217.1 - 2.3e-07 31.3 0.0 6.7e-06 26.6 0.0 3.5 4 0 0 4 4 2 1 Methyltransferase domain Thiolase_N PF00108.18 KXX79217.1 - 9.9e-06 24.7 0.0 2.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 KXX79217.1 - 1.1e-05 25.2 0.0 3.9e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX79217.1 - 0.00018 21.7 0.0 0.00076 19.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79217.1 - 0.0002 21.8 0.0 0.0006 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX79217.1 - 0.00078 19.4 0.0 0.0027 17.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79217.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family COesterase PF00135.23 KXX79217.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.13 KXX79217.1 - 0.11 11.7 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KXX79217.1 - 0.18 11.2 0.0 0.96 8.8 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KXX79217.1 - 0.23 10.8 0.0 1.8 7.8 0.0 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KXX79217.1 - 0.35 9.3 0.1 5.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Methyltransf_28 PF02636.12 KXX79217.1 - 0.63 9.3 0.0 1.1 8.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PhoPQ_related PF10142.4 KXX79217.1 - 1.3 7.4 0.0 2.3 6.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PARP_regulatory PF01358.13 KXX79217.1 - 3.6 6.1 0.0 7 5.1 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Spore_coat_CotO PF14153.1 KXX79218.1 - 0.12 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Fumarate_red_C PF02300.12 KXX79218.1 - 0.13 12.1 1.1 6.9 6.5 0.2 2.1 2 0 0 2 2 2 0 Fumarate reductase subunit C MFS_1 PF07690.11 KXX79219.1 - 1.3e-10 40.5 4.1 1.5e-10 40.3 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 KXX79219.1 - 0.044 13.7 3.9 0.1 12.6 2.6 1.7 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) Sugar_tr PF00083.19 KXX79219.1 - 0.15 10.6 5.6 0.21 10.1 3.9 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Fungal_trans PF04082.13 KXX79220.1 - 6.4e-10 38.3 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79220.1 - 8.2e-06 25.6 7.5 1.5e-05 24.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rib_5-P_isom_A PF06026.9 KXX79221.1 - 4.5e-40 136.7 0.0 3.5e-39 133.8 0.0 1.9 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KXX79221.1 - 0.093 12.3 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain AAA PF00004.24 KXX79222.1 - 1.1e-15 58.0 0.0 2.3e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KXX79222.1 - 0.00019 21.0 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KXX79222.1 - 0.0012 19.0 0.7 0.014 15.5 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX79222.1 - 0.0029 18.4 0.5 0.019 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX79222.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX79222.1 - 0.018 15.0 0.1 0.075 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KXX79222.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain PKD_channel PF08016.7 KXX79223.1 - 1.8e-05 23.3 16.5 0.00087 17.8 11.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KXX79223.1 - 0.013 14.7 19.4 1.5 8.0 13.5 2.3 1 1 0 1 1 1 0 Ion transport protein DUF843 PF05814.6 KXX79223.1 - 1.7 8.4 6.5 0.75 9.6 0.3 2.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) XAP5 PF04921.9 KXX79224.1 - 8.5e-81 271.0 0.0 1.5e-80 270.2 0.0 1.4 2 0 0 2 2 2 1 XAP5, circadian clock regulator Herpes_US12 PF05363.7 KXX79224.1 - 0.12 12.8 3.7 0.12 12.9 0.5 2.5 2 0 0 2 2 2 0 Herpesvirus US12 family Methyltransf_10 PF05971.7 KXX79225.1 - 6.6e-66 222.4 0.0 8.4e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KXX79225.1 - 2e-06 27.8 0.0 3.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX79225.1 - 4.8e-06 26.0 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KXX79225.1 - 1.3e-05 25.7 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79225.1 - 0.0005 19.6 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KXX79225.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KXX79225.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KXX79225.1 - 0.032 14.7 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KXX79225.1 - 0.034 14.5 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KXX79225.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 KXX79225.1 - 0.051 13.1 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein FA_desaturase PF00487.19 KXX79227.1 - 2 7.7 11.6 2.4 7.5 7.8 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Asp PF00026.18 KXX79229.1 - 1.2e-42 146.3 0.1 2.2e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KXX79229.1 - 6.9e-08 32.8 0.0 0.24 11.9 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 KXX79229.1 - 9.1e-07 28.5 0.0 1.2e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KXX79229.1 - 0.00071 19.3 0.0 0.92 9.3 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease SH3_1 PF00018.23 KXX79230.1 - 0.00023 20.4 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX79230.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX79230.1 - 0.054 12.9 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Ank_2 PF12796.2 KXX79231.1 - 1.3e-97 320.2 15.8 2.2e-22 79.2 0.0 7.7 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79231.1 - 1.7e-83 270.5 30.1 5.7e-09 35.3 0.0 14.4 14 0 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.1 KXX79231.1 - 2.6e-60 194.2 13.2 1e-05 25.2 0.0 14.3 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 KXX79231.1 - 1.7e-59 197.1 11.9 9.4e-11 41.9 0.0 10.6 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX79231.1 - 1.1e-53 178.0 21.5 4.7e-09 36.2 0.1 12.5 4 2 9 13 13 13 11 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.3 KXX79231.1 - 0.24 11.4 2.0 0.9 9.6 0.4 2.8 2 0 0 2 2 2 0 Selenocysteine synthase N terminal MRP-L28 PF09812.4 KXX79232.1 - 0.062 13.1 3.2 2.3 8.0 0.9 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 Phlebovirus_NSM PF07246.6 KXX79232.1 - 0.23 10.5 4.3 0.38 9.8 3.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sipho_Gp157 PF05565.6 KXX79232.1 - 0.27 10.7 3.8 0.47 10.0 2.7 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4140 PF13600.1 KXX79232.1 - 0.43 11.0 4.1 15 6.0 1.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.11 KXX79233.1 - 3.1e-39 134.6 32.5 4e-39 134.3 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2142 PF09913.4 KXX79233.1 - 0.01 14.5 9.5 0.017 13.8 5.2 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2142) ESSS PF10183.4 KXX79233.1 - 1.3 9.4 3.3 1.8 8.9 0.3 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cytochrom_B561 PF03188.11 KXX79234.1 - 2.6e-05 24.0 11.4 5.1e-05 23.1 7.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KXX79234.1 - 0.0079 15.7 0.4 0.0079 15.7 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) MFS_1 PF07690.11 KXX79236.1 - 5.6e-14 51.6 8.6 7e-11 41.4 1.1 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX79236.1 - 0.029 12.9 2.7 0.035 12.6 0.3 2.0 2 0 0 2 2 2 0 Sugar (and other) transporter DUF21 PF01595.15 KXX79236.1 - 0.11 11.8 0.6 0.23 10.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF3817 PF12823.2 KXX79237.1 - 4.4 7.8 12.3 3.2 8.2 2.1 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) UDPGT PF00201.13 KXX79238.1 - 8.2e-14 51.0 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 KXX79238.1 - 0.012 15.4 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Rep_fac_C PF08542.6 KXX79239.1 - 4.1e-19 68.3 0.2 1.4e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 KXX79239.1 - 1.9e-16 60.4 1.2 1.3e-15 57.7 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KXX79239.1 - 4.1e-14 52.5 0.0 8.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KXX79239.1 - 1.7e-09 36.9 0.0 3.4e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KXX79239.1 - 1.7e-07 31.4 0.8 1.1e-06 28.8 0.1 2.5 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.1 KXX79239.1 - 2e-06 27.4 0.0 5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KXX79239.1 - 2.4e-06 27.6 0.0 3.4e-05 23.9 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 KXX79239.1 - 1e-05 24.4 0.0 0.029 13.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_11 PF13086.1 KXX79239.1 - 1.2e-05 24.9 0.1 0.00026 20.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 KXX79239.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KXX79239.1 - 2.5e-05 24.2 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX79239.1 - 4.2e-05 22.6 0.1 0.00023 20.2 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX79239.1 - 4.7e-05 23.1 0.2 0.00013 21.7 0.1 1.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 KXX79239.1 - 5.1e-05 22.8 0.0 8.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 KXX79239.1 - 9e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX79239.1 - 0.00016 21.3 0.0 0.00048 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KXX79239.1 - 0.00039 20.0 0.1 0.0016 18.0 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KXX79239.1 - 0.00081 18.6 0.7 0.99 8.5 0.0 2.8 2 1 0 3 3 2 2 PhoH-like protein DUF2075 PF09848.4 KXX79239.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KXX79239.1 - 0.0026 17.1 0.2 0.021 14.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KXX79239.1 - 0.0053 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KXX79239.1 - 0.0057 16.3 0.1 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase DEAD PF00270.24 KXX79239.1 - 0.0076 15.7 0.1 0.11 12.0 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KXX79239.1 - 0.014 14.8 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 KXX79239.1 - 0.015 14.7 0.2 1 8.7 0.1 2.6 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KXX79239.1 - 0.02 15.6 0.0 0.045 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KXX79239.1 - 0.021 13.9 0.2 0.14 11.3 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KXX79239.1 - 0.026 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TAFII28 PF04719.9 KXX79239.1 - 0.031 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 hTAFII28-like protein conserved region ResIII PF04851.10 KXX79239.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 KXX79239.1 - 0.043 13.2 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family SNF2_N PF00176.18 KXX79239.1 - 0.049 12.4 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain TK PF00265.13 KXX79239.1 - 0.056 13.0 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 1 0 Thymidine kinase RNA_pol_Rpc34 PF05158.7 KXX79239.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit RNA_helicase PF00910.17 KXX79239.1 - 0.088 12.9 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 RNA helicase MiaE PF06175.6 KXX79239.1 - 0.091 12.1 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) ABC_tran PF00005.22 KXX79239.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TauD PF02668.11 KXX79242.1 - 6.2e-42 144.0 0.0 7.4e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidohydro_4 PF13147.1 KXX79244.1 - 8.3e-14 52.2 9.3 1.4e-13 51.4 6.4 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX79244.1 - 3.9e-12 46.4 0.4 6.9e-06 25.9 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KXX79244.1 - 6.6e-08 32.2 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX79244.1 - 0.00081 18.7 7.5 0.02 14.0 0.9 2.6 2 1 0 2 2 2 2 Amidohydrolase family COX16 PF14138.1 KXX79245.1 - 3.7e-26 91.0 0.3 4.1e-26 90.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.2 KXX79245.1 - 0.03 14.5 0.5 0.043 14.0 0.3 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sel1 PF08238.7 KXX79247.1 - 1.9e-44 149.1 20.8 2.7e-07 31.0 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.1 KXX79247.1 - 0.18 11.9 2.7 0.2 11.8 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KXX79248.1 - 3.5e-59 200.0 0.0 5.2e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79248.1 - 1.7e-37 128.9 0.0 1.1e-36 126.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79248.1 - 0.00027 20.0 0.0 0.00056 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 KXX79248.1 - 0.011 14.6 0.0 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 DUF607 PF04678.8 KXX79248.1 - 0.28 11.0 2.7 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF607 APG6 PF04111.7 KXX79248.1 - 2.1 7.3 8.4 3.8 6.4 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C2H2 PF00096.21 KXX79249.1 - 3.3e-09 36.5 11.0 0.00036 20.6 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX79249.1 - 5.7e-07 29.5 9.4 8.3e-07 29.0 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX79249.1 - 2.4e-05 24.3 9.1 0.0062 16.7 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KXX79249.1 - 0.018 15.2 3.4 0.036 14.2 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX79249.1 - 0.046 13.8 5.8 0.064 13.4 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.3 KXX79249.1 - 1.1 8.9 3.3 20 4.9 0.9 2.2 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-BED PF02892.10 KXX79249.1 - 1.9 8.3 5.8 12 5.7 0.4 2.5 1 1 1 2 2 2 0 BED zinc finger GDI PF00996.13 KXX79250.1 - 5.5e-36 123.8 0.0 8.2e-36 123.2 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 KXX79251.1 - 1.5e-27 95.7 0.0 2.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KXX79251.1 - 3.9e-08 32.3 0.1 8.7e-08 31.2 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ALO PF04030.9 KXX79252.1 - 2.2e-93 312.5 0.4 2.8e-93 312.2 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KXX79252.1 - 9e-31 106.2 0.1 1.3e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.26 KXX79253.1 - 1.1e-25 89.7 1.0 1.1e-12 47.9 0.2 3.2 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 KXX79253.1 - 1.3e-10 41.4 0.0 3.6e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79253.1 - 2.3e-10 39.7 0.4 0.0001 21.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KXX79253.1 - 1e-06 28.3 0.1 0.0023 18.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KXX79253.1 - 1.1e-06 28.9 0.1 3.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX79253.1 - 1.4e-05 25.1 0.0 4.2e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MPC PF03650.8 KXX79254.1 - 2.3e-41 140.4 0.3 2.9e-41 140.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 KXX79255.1 - 8.3e-11 41.4 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Abhydrolase_6 PF12697.2 KXX79256.1 - 5.9e-21 75.3 2.1 5.9e-21 75.3 1.4 2.2 2 2 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79256.1 - 3.6e-10 39.7 0.0 3.3e-09 36.6 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX79256.1 - 2.7e-07 30.3 0.0 4.2e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX79256.1 - 6.9e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KXX79256.1 - 0.0055 16.4 0.0 0.64 9.6 0.0 2.8 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KXX79256.1 - 0.018 14.2 0.0 0.079 12.2 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family RNase_PH PF01138.16 KXX79257.1 - 3.5e-17 62.9 0.0 2e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KXX79257.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Serglycin PF04360.7 KXX79257.1 - 0.091 12.4 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Serglycin tRNA-synt_His PF13393.1 KXX79258.1 - 0.0059 15.6 0.5 0.069 12.1 0.1 2.0 1 1 1 2 2 2 2 Histidyl-tRNA synthetase DUF4655 PF15548.1 KXX79258.1 - 0.039 12.8 2.2 0.051 12.4 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) DUF1687 PF07955.6 KXX79259.1 - 1.9e-20 73.1 2.0 8e-20 71.1 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) DUF2365 PF10157.4 KXX79260.1 - 8.9e-05 22.4 0.3 0.00013 21.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) SMP_2 PF10144.4 KXX79260.1 - 0.0071 15.4 0.2 0.0093 15.1 0.1 1.2 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin Ssu72 PF04722.8 KXX79260.1 - 0.029 13.6 0.6 0.039 13.2 0.4 1.1 1 0 0 1 1 1 0 Ssu72-like protein COG5 PF10392.4 KXX79260.1 - 0.1 12.5 1.0 1.1 9.2 0.1 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 UreE_C PF05194.7 KXX79260.1 - 0.52 10.4 5.3 0.2 11.7 1.4 1.9 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain Lipase_GDSL_2 PF13472.1 KXX79261.1 - 7.9e-10 39.1 0.7 2.3e-09 37.6 0.5 1.8 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX79261.1 - 2.4e-08 34.1 5.3 1.2e-07 31.8 3.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KXX79261.1 - 0.0083 15.8 0.1 0.87 9.2 0.0 2.3 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family SCO1-SenC PF02630.9 KXX79262.1 - 7.4e-60 201.5 0.0 1.2e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KXX79262.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KXX79262.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KXX79262.1 - 0.0053 16.2 0.0 0.14 11.6 0.0 2.2 1 1 0 1 1 1 1 Redoxin PHD PF00628.24 KXX79263.1 - 3.6e-12 45.7 7.6 3.6e-12 45.7 5.3 2.1 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KXX79263.1 - 1.1 9.1 6.0 2.2 8.1 4.2 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3433 PF11915.3 KXX79264.1 - 2.2e-27 95.0 12.7 1.2e-26 92.6 0.9 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Choline_kinase PF01633.15 KXX79265.1 - 8.2e-60 201.9 0.0 2.1e-59 200.6 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KXX79265.1 - 1.5e-21 75.5 0.0 3.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KXX79265.1 - 2.5e-06 27.4 0.1 2.5e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family DASH_Dad2 PF08654.5 KXX79265.1 - 0.029 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad2 Ribosomal_L24e PF01246.15 KXX79268.1 - 1.3e-30 105.0 0.3 1.3e-30 105.0 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e A_deamin PF02137.13 KXX79269.1 - 7.4e-56 189.9 0.0 8e-55 186.5 0.0 2.0 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.13 KXX79270.1 - 2.9e-22 77.9 0.7 9.2e-22 76.3 0.1 1.9 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.6 KXX79271.1 - 4.3e-40 136.2 2.4 5.4e-40 135.9 1.6 1.1 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 KXX79271.1 - 0.018 14.9 0.9 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) ATP-synt_F6 PF05511.6 KXX79271.1 - 0.022 14.6 0.7 0.048 13.5 0.4 1.7 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 MSP7_C PF12948.2 KXX79271.1 - 0.049 13.8 0.7 0.062 13.5 0.5 1.1 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain SRP-alpha_N PF04086.8 KXX79271.1 - 0.11 11.8 5.4 0.12 11.7 3.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SLY PF12485.3 KXX79271.1 - 0.19 11.9 3.1 0.23 11.6 2.1 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Seryl_tRNA_N PF02403.17 KXX79271.1 - 0.2 11.6 6.6 0.39 10.7 4.6 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 KXX79271.1 - 6.3 6.7 7.8 8.6 6.2 5.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1348 PF07080.6 KXX79274.1 - 1e-59 200.4 7.0 1.2e-59 200.1 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KXX79274.1 - 4.3e-08 33.4 1.2 6.8e-08 32.8 0.8 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KXX79274.1 - 1.5e-06 28.3 0.2 2.2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 KXX79274.1 - 0.073 12.6 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Redoxin PF08534.5 KXX79275.1 - 6e-37 126.4 0.0 6.7e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KXX79275.1 - 2.8e-11 43.1 0.0 3.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Fumble PF03630.9 KXX79276.1 - 4.6e-130 433.4 0.0 4.4e-129 430.2 0.0 2.1 1 1 0 1 1 1 1 Fumble Zip PF02535.17 KXX79276.1 - 0.0022 17.0 2.1 0.0031 16.5 1.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 KXX79276.1 - 0.0029 17.0 8.2 0.0044 16.4 5.7 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SPT16 PF08644.6 KXX79278.1 - 6.4e-58 194.9 0.1 2.8e-57 192.8 0.1 2.2 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KXX79278.1 - 8.6e-54 181.4 0.4 2.5e-53 179.9 0.3 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KXX79278.1 - 3.4e-25 88.8 0.0 6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KXX79278.1 - 2e-22 78.9 0.0 5.4e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Cyt-b5 PF00173.23 KXX79279.1 - 3.2e-14 52.4 0.0 4.5e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2197 PF09963.4 KXX79280.1 - 0.069 13.1 5.5 0.042 13.8 2.5 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2 PF00096.21 KXX79281.1 - 0.00071 19.7 32.3 0.0049 17.1 4.9 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX79281.1 - 0.0021 18.2 4.9 0.0021 18.2 3.4 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger DUF3133 PF11331.3 KXX79281.1 - 0.038 13.5 0.5 3.8 7.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-C2H2_4 PF13894.1 KXX79282.1 - 0.0011 19.1 12.1 0.25 11.7 0.2 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-TRAF PF02176.13 KXX79282.1 - 0.064 13.6 0.8 0.064 13.6 0.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger PPR_2 PF13041.1 KXX79284.1 - 3.1e-20 71.8 0.0 3.1e-10 39.8 0.0 3.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KXX79284.1 - 5.8e-15 54.2 6.3 0.0019 18.3 0.0 6.5 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 KXX79284.1 - 2.4e-13 49.0 4.7 0.0014 18.4 0.0 6.6 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 KXX79284.1 - 1.5e-12 46.7 5.6 1.7e-05 24.1 0.0 6.7 7 0 0 7 7 7 3 PPR repeat cwf18 PF08315.7 KXX79285.1 - 5.3e-44 149.7 5.5 5.3e-44 149.7 3.8 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF2057 PF09829.4 KXX79285.1 - 0.019 14.6 0.4 0.019 14.6 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) WD40 PF00400.27 KXX79286.1 - 2.3e-42 141.3 4.4 7.5e-14 50.9 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 KXX79286.1 - 6.5e-16 58.4 1.2 1.6e-13 50.6 0.8 2.2 1 1 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KXX79286.1 - 4.6e-06 25.0 6.7 0.0076 14.4 0.3 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1258 PF06869.7 KXX79286.1 - 0.00014 21.0 0.1 0.29 10.1 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 KXX79286.1 - 0.00036 20.0 1.9 0.0039 16.6 0.9 2.1 1 1 1 2 2 2 1 PQQ-like domain PD40 PF07676.7 KXX79286.1 - 0.00039 20.0 0.8 2.9 7.6 0.0 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 KXX79286.1 - 0.0023 17.6 0.0 0.0072 16.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KXX79286.1 - 0.0044 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF1652 PF07865.6 KXX79286.1 - 0.0095 15.5 0.1 19 4.9 0.0 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.11 KXX79286.1 - 0.02 13.2 0.2 1.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Germane PF10646.4 KXX79286.1 - 0.037 14.2 0.0 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 Sporulation and spore germination Proteasome_A_N PF10584.4 KXX79286.1 - 0.053 12.8 0.5 1.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature AFG1_ATPase PF03969.11 KXX79286.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.17 KXX79286.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KXX79286.1 - 0.1 12.7 0.6 0.97 9.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KXX79286.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NYD-SP28_assoc PF14775.1 KXX79286.1 - 0.13 11.9 0.7 46 3.8 0.0 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Ceramidase_alk PF04734.8 KXX79287.1 - 7.3e-274 909.8 0.0 8.3e-274 909.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Glyco_hydro_61 PF03443.9 KXX79288.1 - 2.9e-65 220.1 0.1 3.6e-65 219.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kelch_3 PF13415.1 KXX79289.1 - 5.6e-27 93.2 21.4 2.6e-07 30.5 0.1 8.7 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX79289.1 - 4e-20 71.3 11.6 2.4e-06 27.3 0.1 7.2 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 KXX79289.1 - 4.8e-16 58.1 10.3 1e-05 25.4 0.0 6.7 6 2 2 8 8 8 3 Kelch motif Kelch_1 PF01344.20 KXX79289.1 - 3.4e-15 55.3 0.3 1.1e-06 28.0 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 KXX79289.1 - 6.4e-15 54.6 23.1 0.00061 19.5 0.0 7.6 7 2 1 8 8 8 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX79289.1 - 2.3e-11 42.9 8.7 1.1e-05 25.0 0.9 6.0 5 1 0 5 5 5 2 Kelch motif SPOR PF05036.8 KXX79289.1 - 0.0072 16.4 0.1 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Sporulation related domain 2Fe-2S_thioredx PF01257.14 KXX79290.1 - 1.2e-59 200.0 0.1 1.6e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.7 KXX79290.1 - 0.0035 17.3 0.2 0.0079 16.2 0.1 1.5 1 0 0 1 1 1 1 Heat shock protein 9/12 CDC50 PF03381.10 KXX79291.1 - 2.9e-88 295.6 0.1 3.5e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.5 KXX79291.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 cNMP_binding PF00027.24 KXX79292.1 - 4.3e-43 145.0 0.0 1.6e-21 75.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 KXX79292.1 - 0.11 11.5 0.0 0.35 9.8 0.0 1.8 2 0 0 2 2 2 0 GXGXG motif ALAD PF00490.16 KXX79294.1 - 3.1e-118 394.3 0.0 3.6e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_3 PF01757.17 KXX79295.1 - 2.4e-50 171.2 33.4 3.8e-50 170.6 23.2 1.3 1 1 0 1 1 1 1 Acyltransferase family DUF883 PF05957.8 KXX79296.1 - 1.5 9.2 10.7 0.26 11.6 4.1 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Ribosomal_L17 PF01196.14 KXX79297.1 - 9.9e-32 109.3 0.1 1.9e-31 108.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 Mn_catalase PF05067.7 KXX79297.1 - 0.025 13.3 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase ATP-synt_B PF00430.13 KXX79297.1 - 0.071 12.9 0.6 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF1253 PF06862.7 KXX79298.1 - 1.8e-167 557.2 0.2 2.5e-167 556.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) APH_6_hur PF04655.9 KXX79298.1 - 0.015 14.4 2.8 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase MitMem_reg PF13012.1 KXX79299.1 - 1.9e-15 56.9 0.1 3e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KXX79299.1 - 8.2e-15 54.5 0.0 1.4e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SUZ PF12752.2 KXX79300.1 - 5.7e-15 55.5 2.9 5.7e-15 55.5 2.0 2.6 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 KXX79300.1 - 1.1e-07 31.4 0.2 2.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.15 KXX79300.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Ribosomal_S4 PF00163.14 KXX79301.1 - 5.2e-12 45.9 4.2 8.8e-12 45.2 2.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KXX79301.1 - 1.6e-11 43.4 0.0 4.7e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 S4 domain Y_phosphatase3 PF13350.1 KXX79302.1 - 2e-30 106.2 0.0 2.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KXX79302.1 - 1.7e-11 44.0 0.1 2.9e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family C-terminal region PTPlike_phytase PF14566.1 KXX79302.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 KXX79302.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HeLo PF14479.1 KXX79303.1 - 1.2e-44 152.6 0.0 1.5e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 KXX79303.1 - 5.1e-24 84.0 1.5 8.3e-24 83.3 1.0 1.4 1 0 0 1 1 1 1 Het-s 218-289 DUF956 PF06115.6 KXX79303.1 - 0.093 12.3 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF956) BCAS2 PF05700.6 KXX79304.1 - 1.2e-39 136.0 0.0 1.4e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KXX79304.1 - 0.025 14.3 0.2 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PMP1_2 PF08114.6 KXX79305.1 - 0.0058 16.0 0.2 0.0093 15.4 0.1 1.4 1 0 0 1 1 1 1 ATPase proteolipid family UPF0542 PF15086.1 KXX79305.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Baculo_11_kDa PF06143.6 KXX79305.1 - 0.16 11.3 0.4 0.24 10.7 0.3 1.4 1 1 0 1 1 1 0 Baculovirus 11 kDa family Pyridoxal_deC PF00282.14 KXX79306.1 - 1.2e-23 83.2 0.0 1.6e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 KXX79306.1 - 0.0024 16.4 0.0 0.0032 15.9 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 KXX79306.1 - 0.0044 16.1 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KXX79306.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX79306.1 - 0.12 11.0 0.0 0.3 9.7 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class-V DUF2462 PF09495.5 KXX79307.1 - 4.4e-10 40.1 10.9 5.9e-10 39.7 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.11 KXX79307.1 - 0.052 12.9 1.0 0.055 12.8 0.7 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease ArfGap PF01412.13 KXX79308.1 - 4.6e-39 132.8 0.5 7.5e-39 132.1 0.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Methyltransf_23 PF13489.1 KXX79309.1 - 4.9e-16 58.8 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79309.1 - 1e-08 35.6 0.0 1.1e-07 32.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79309.1 - 1.6e-07 31.0 0.0 2.2e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79309.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79309.1 - 1.2e-05 25.7 0.0 8e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KXX79309.1 - 0.00055 19.3 0.0 0.006 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX79309.1 - 0.0017 18.3 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX79309.1 - 0.002 18.4 0.0 0.0062 16.8 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79309.1 - 0.017 14.2 0.0 0.15 11.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KXX79309.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FTA4 PF13093.1 KXX79310.1 - 1.6e-66 223.8 0.0 1.8e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Glypican PF01153.14 KXX79310.1 - 1 7.8 6.8 0.44 9.0 0.0 2.2 1 1 1 2 2 2 0 Glypican Peptidase_C2 PF00648.16 KXX79311.1 - 2.2e-59 200.8 0.4 5.4e-38 130.6 0.4 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease DNA_pol_phi PF04931.8 KXX79311.1 - 7.6 4.1 10.7 13 3.4 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S18 PF01084.15 KXX79312.1 - 7.2e-13 48.1 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.1 KXX79313.1 - 4.2e-08 32.8 0.2 0.00026 20.9 0.0 4.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 KXX79313.1 - 3.2e-05 23.6 0.1 8.4 6.6 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.1 KXX79313.1 - 0.0022 17.9 0.5 6.2 6.8 0.0 4.6 6 0 0 6 6 6 1 PPR repeat family BTAD PF03704.12 KXX79313.1 - 0.0038 17.5 3.5 1.7 8.9 0.0 3.0 2 0 0 2 2 2 2 Bacterial transcriptional activator domain ThiF PF00899.16 KXX79314.1 - 2.1e-29 102.0 0.0 4.8e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KXX79314.1 - 0.018 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 KXX79315.1 - 1.6e-26 91.9 2.3 2.4e-26 91.3 1.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KXX79315.1 - 0.00034 20.9 0.0 0.0008 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX79315.1 - 0.0015 19.3 0.0 0.0039 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF3129 PF11327.3 KXX79316.1 - 1.4e-61 207.5 6.6 1.8e-61 207.2 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) ADH_N PF08240.7 KXX79317.1 - 4.2e-20 71.5 4.1 8.2e-20 70.5 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX79317.1 - 1e-17 63.8 0.1 2.2e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX79317.1 - 0.00019 22.3 0.0 0.00046 21.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1537 PF07005.6 KXX79317.1 - 0.038 13.6 0.7 0.56 9.8 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF1537 AlaDh_PNT_C PF01262.16 KXX79317.1 - 0.074 12.6 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KXX79317.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HET PF06985.6 KXX79318.1 - 8.2e-18 64.9 0.0 2.7e-17 63.2 0.0 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DZR PF12773.2 KXX79318.1 - 0.067 13.0 2.7 0.32 10.8 2.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon Sugar_tr PF00083.19 KXX79319.1 - 3.5e-22 78.6 8.1 3.5e-17 62.1 3.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX79319.1 - 9.3e-07 27.8 7.6 9.3e-07 27.8 5.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KXX79319.1 - 0.0072 15.1 4.6 0.011 14.5 3.2 1.4 1 0 0 1 1 1 1 Nucleoside H+ symporter DUF3679 PF12438.3 KXX79319.1 - 0.044 13.1 0.1 0.32 10.3 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3679) Methyltransf_23 PF13489.1 KXX79320.1 - 1.8e-22 79.7 0.0 2.6e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79320.1 - 1.9e-08 34.8 0.0 1.6e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79320.1 - 1.7e-07 30.9 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79320.1 - 4e-07 30.4 0.0 7.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79320.1 - 1e-06 29.1 0.0 6.6e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79320.1 - 0.00066 18.8 0.0 0.013 14.6 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KXX79320.1 - 0.001 18.6 0.1 0.028 13.9 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KXX79320.1 - 0.0019 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KXX79320.1 - 0.0087 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KXX79320.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 KXX79320.1 - 0.094 11.8 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 KXX79320.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain eIF3g PF12353.3 KXX79321.1 - 6.9e-45 152.0 3.4 1.1e-44 151.3 2.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KXX79321.1 - 1.8e-15 56.3 0.1 3.6e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX79321.1 - 1.5e-13 50.4 0.1 3.3e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79321.1 - 1e-07 31.6 0.6 1.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 KXX79323.1 - 1.5e-56 189.0 10.5 2e-35 121.1 1.4 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF1777 PF08648.7 KXX79324.1 - 0.31 10.7 14.1 0.41 10.3 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CAF-1_p150 PF11600.3 KXX79324.1 - 1.9 7.8 22.7 3.8 6.8 0.3 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OAD_gamma PF04277.8 KXX79324.1 - 6.1 7.2 8.1 0.39 11.1 0.8 2.4 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain adh_short PF00106.20 KXX79325.1 - 6.6e-12 45.6 0.0 1.5e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX79325.1 - 0.004 16.8 0.1 0.0068 16.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Vfa1 PF08432.5 KXX79326.1 - 7.5e-59 198.8 18.9 8.4e-59 198.6 13.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 KXX79326.1 - 0.34 9.4 8.4 0.41 9.1 5.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 KXX79326.1 - 0.37 10.1 21.1 0.46 9.8 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KXX79326.1 - 0.4 8.6 18.8 0.45 8.4 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.4 KXX79326.1 - 0.47 10.7 14.0 0.59 10.4 9.7 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Astro_capsid PF03115.9 KXX79326.1 - 0.56 8.3 8.3 0.65 8.1 5.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Ycf1 PF05758.7 KXX79326.1 - 2.5 5.6 13.7 3 5.4 9.5 1.1 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 KXX79326.1 - 3.3 5.4 13.1 4 5.1 9.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2201_N PF13203.1 KXX79326.1 - 4.5 6.3 10.4 5.6 6.0 7.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP11 PF06644.6 KXX79326.1 - 4.7 6.6 14.5 6.1 6.2 10.1 1.1 1 0 0 1 1 1 0 ATP11 protein DUF4407 PF14362.1 KXX79326.1 - 9.5 5.0 11.3 12 4.7 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF607 PF04678.8 KXX79327.1 - 1.2e-38 132.8 2.8 1.6e-38 132.4 0.1 2.5 2 1 0 2 2 2 1 Protein of unknown function, DUF607 DUF2968 PF11180.3 KXX79327.1 - 0.033 13.5 1.9 4.5 6.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) zf-C2H2_4 PF13894.1 KXX79328.1 - 0.00018 21.5 24.0 0.044 14.1 2.2 5.1 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX79328.1 - 0.011 16.0 1.3 0.011 16.0 0.9 3.5 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.21 KXX79328.1 - 0.023 15.0 26.0 0.11 12.8 2.0 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KXX79328.1 - 5.3 7.3 13.8 0.48 10.6 2.9 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 KXX79329.1 - 1.1e-17 63.8 0.1 2.3e-09 36.9 0.1 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain ADH_zinc_N_2 PF13602.1 KXX79329.1 - 0.034 15.0 0.0 2.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Thiolase_N PF00108.18 KXX79329.1 - 0.075 12.0 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain Glyco_hydro_114 PF03537.8 KXX79330.1 - 1.2e-08 34.5 0.1 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 HET PF06985.6 KXX79331.1 - 0.0012 19.0 0.1 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Alpha_L_fucos PF01120.12 KXX79332.1 - 3.4e-27 95.2 0.0 6.7e-27 94.2 0.0 1.4 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 KXX79332.1 - 1.7e-09 37.6 0.4 7.2e-09 35.5 0.0 2.2 2 1 1 3 3 3 1 F5/8 type C domain Sugar_tr PF00083.19 KXX79333.1 - 6.9e-22 77.6 21.7 7.4e-21 74.2 12.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter Tyrosinase PF00264.15 KXX79334.1 - 5.2e-51 173.9 1.7 7.1e-51 173.4 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 KXX79335.1 - 1.3e-13 50.3 41.8 7.4e-12 44.6 20.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KXX79335.1 - 0.16 11.9 10.6 0.15 12.0 1.5 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Ldr_toxin PF13940.1 KXX79335.1 - 1.3 8.8 6.6 0.13 12.0 0.8 2.3 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Ilm1 PF10311.4 KXX79335.1 - 2.8 7.4 6.0 14 5.1 0.2 2.3 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Glyoxalase PF00903.20 KXX79336.1 - 0.0046 16.9 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KXX79336.1 - 0.033 14.8 0.0 0.065 13.8 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain CorA PF01544.13 KXX79338.1 - 3.3e-09 36.1 0.2 7.5e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cupin_2 PF07883.6 KXX79339.1 - 5.7e-11 41.7 0.0 1.3e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KXX79339.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 KXX79339.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Alpha-amylase PF00128.19 KXX79340.1 - 2e-18 66.8 0.2 2e-17 63.6 0.2 2.4 1 1 1 2 2 2 1 Alpha amylase, catalytic domain DUF1939 PF09154.5 KXX79340.1 - 0.028 14.3 0.1 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.11 KXX79340.1 - 0.074 10.8 0.0 4 5.0 0.0 2.3 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 ABC_tran PF00005.22 KXX79341.1 - 1.2e-25 90.3 0.0 2e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KXX79341.1 - 2.6e-12 46.3 5.5 4.8e-12 45.4 3.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter DUF258 PF03193.11 KXX79341.1 - 0.00054 19.1 0.2 0.001 18.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KXX79341.1 - 0.0025 17.2 0.4 0.047 13.0 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KXX79341.1 - 0.0028 17.6 0.0 0.12 12.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KXX79341.1 - 0.016 14.7 0.7 0.034 13.6 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 KXX79341.1 - 0.031 13.4 1.0 0.049 12.7 0.7 1.2 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 KXX79341.1 - 0.038 13.4 0.3 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KXX79341.1 - 0.068 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 KXX79341.1 - 0.096 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin family SbcCD_C PF13558.1 KXX79341.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IIGP PF05049.8 KXX79341.1 - 0.63 8.7 0.5 0.98 8.1 0.3 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.12 KXX79341.1 - 2 8.1 2.4 3.4 7.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Methyltransf_11 PF08241.7 KXX79343.1 - 8.6e-07 29.3 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79343.1 - 0.0018 17.4 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX79343.1 - 0.025 14.9 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KXX79343.1 - 0.055 13.1 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79343.1 - 0.068 12.7 0.0 0.1 12.2 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79343.1 - 0.083 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_8 PF13523.1 KXX79344.1 - 2.2e-37 128.2 0.1 3.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CVNH PF08881.5 KXX79346.1 - 3.1e-31 107.6 0.0 3.5e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 CVNH domain Rtt106 PF08512.7 KXX79347.1 - 1.9e-26 91.8 0.0 7.6e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like HET PF06985.6 KXX79348.1 - 6.5e-23 81.4 0.0 1.2e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 KXX79350.1 - 1.6e-60 204.7 0.0 2.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79350.1 - 2.3e-39 134.9 0.0 4.9e-39 133.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX79350.1 - 2e-07 30.2 0.0 0.0065 15.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX79350.1 - 1.2e-06 27.7 0.3 1.2e-05 24.3 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX79350.1 - 0.0003 20.7 0.2 0.00075 19.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX79350.1 - 0.00063 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX79350.1 - 0.00075 19.4 0.0 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX79350.1 - 0.0022 17.1 0.2 0.0069 15.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KXX79350.1 - 0.0074 16.3 0.4 2.6 8.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX79350.1 - 0.063 13.0 1.6 0.12 12.1 0.1 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KXX79350.1 - 0.067 11.6 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KXX79350.1 - 0.12 11.3 0.1 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KXX79350.1 - 0.16 10.5 0.2 0.27 9.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase BATS PF06968.8 KXX79352.1 - 1.4e-30 105.0 0.1 5.2e-30 103.1 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KXX79352.1 - 9e-18 64.9 0.2 1.4e-17 64.3 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.16 KXX79353.1 - 7.6e-34 117.2 0.0 9e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3638 PF12340.3 KXX79354.1 - 4.6e-63 212.2 2.3 1.5e-55 187.7 0.0 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KXX79354.1 - 3.8e-18 64.2 1.5 8.3e-18 63.2 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Ribosomal_L4 PF00573.17 KXX79354.1 - 0.26 10.6 0.0 0.58 9.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Dicty_CAR PF05462.6 KXX79355.1 - 7.3e-15 54.6 7.7 7.3e-15 54.6 5.3 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KXX79355.1 - 4.6e-08 32.8 11.3 9.4e-08 31.8 7.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 FA_hydroxylase PF04116.8 KXX79356.1 - 1.4e-16 60.9 22.0 1.4e-16 60.9 15.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SKG6 PF08693.5 KXX79357.1 - 0.005 16.1 3.5 0.01 15.1 2.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.7 KXX79357.1 - 0.047 13.5 0.2 12 5.8 0.1 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF3405 PF11885.3 KXX79358.1 - 5e-130 434.0 0.5 1.7e-129 432.3 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Aldose_epim PF01263.15 KXX79359.1 - 5.9e-50 170.0 0.1 6.9e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Aminotran_3 PF00202.16 KXX79360.1 - 6.3e-44 150.2 0.0 5.5e-24 84.6 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KXX79360.1 - 6.9e-29 100.8 0.0 1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DIM1 PF02966.11 KXX79361.1 - 5.6e-68 226.5 0.3 6.3e-68 226.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KXX79361.1 - 0.021 14.4 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 KXX79361.1 - 0.072 13.2 0.1 0.097 12.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like FAD_binding_3 PF01494.14 KXX79362.1 - 5.7e-21 74.9 0.0 1.7e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KXX79362.1 - 0.00024 21.0 0.7 0.00063 19.7 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KXX79362.1 - 0.0026 16.4 0.6 0.026 13.1 0.3 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 KXX79362.1 - 0.0072 15.2 2.0 0.015 14.2 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX79362.1 - 0.027 13.3 1.0 0.053 12.3 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_67M PF07488.7 KXX79363.1 - 8.4e-154 511.3 0.0 1.1e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KXX79363.1 - 1.3e-95 319.0 0.2 2.4e-95 318.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KXX79363.1 - 1.3e-26 93.0 0.0 4.1e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KXX79363.1 - 0.0043 17.5 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4448 PF14610.1 KXX79365.1 - 0.012 15.1 0.1 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SH PF01445.12 KXX79365.1 - 0.24 11.0 2.2 0.33 10.6 1.5 1.2 1 0 0 1 1 1 0 Viral small hydrophobic protein Glyco_transf_36 PF06165.6 KXX79367.1 - 9.6e-21 73.6 0.0 1.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 KXX79367.1 - 5.6e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 KXX79367.1 - 0.0097 14.6 0.1 0.017 13.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Melibiase PF02065.13 KXX79368.1 - 5.7e-19 68.0 1.7 1.5e-17 63.3 0.8 2.4 1 1 0 1 1 1 1 Melibiase DUF1996 PF09362.5 KXX79369.1 - 1.2e-83 280.4 0.4 1.4e-83 280.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_33 PF10017.4 KXX79370.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent MetW PF07021.7 KXX79370.1 - 0.084 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW zf-Paramyx-P PF13008.2 KXX79371.1 - 0.1 11.8 1.2 0.21 10.7 0.9 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Lipase_GDSL PF00657.17 KXX79372.1 - 9.8e-13 48.4 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 KXX79372.1 - 3.8e-10 39.2 7.4 3.8e-10 39.2 5.1 2.9 4 0 0 4 4 4 1 Fungal cellulose binding domain FAD_binding_3 PF01494.14 KXX79373.1 - 1.6e-13 50.4 0.0 3.3e-07 29.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Esterase_phd PF10503.4 KXX79374.1 - 3.2e-21 75.5 2.2 5.3e-21 74.8 1.5 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX79374.1 - 2.6e-09 36.6 0.3 6.3e-09 35.3 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX79374.1 - 3.6e-09 36.5 1.1 5.5e-09 35.9 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX79374.1 - 0.0028 17.5 6.2 0.0072 16.2 4.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX79374.1 - 0.0035 16.9 0.1 0.0076 15.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold GMC_oxred_N PF00732.14 KXX79375.1 - 1.5e-60 204.8 0.0 1.9e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79375.1 - 7.3e-35 120.3 0.1 1.5e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX79375.1 - 6.1e-07 28.6 0.0 0.00014 20.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX79375.1 - 1.4e-06 28.2 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX79375.1 - 2.4e-06 27.5 0.0 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX79375.1 - 2.1e-05 24.7 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX79375.1 - 2.7e-05 23.2 0.2 0.00014 20.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KXX79375.1 - 0.00014 20.9 0.1 0.00032 19.7 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KXX79375.1 - 0.0013 17.3 0.1 0.014 13.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KXX79375.1 - 0.025 13.6 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KXX79375.1 - 0.082 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX79375.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mid2 PF04478.7 KXX79376.1 - 0.00069 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KXX79376.1 - 0.073 12.3 0.3 0.073 12.3 0.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2650 PF10853.3 KXX79376.1 - 0.12 11.8 0.4 0.12 11.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Skp1 PF01466.14 KXX79377.1 - 1.8e-29 101.5 0.1 3.2e-29 100.7 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KXX79377.1 - 2.6e-06 27.4 1.0 4.7e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain IMS PF00817.15 KXX79377.1 - 0.004 16.9 0.0 0.056 13.2 0.0 2.1 1 1 1 2 2 2 1 impB/mucB/samB family RGS PF00615.14 KXX79378.1 - 8.8e-07 29.0 0.1 1.6e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain EamA PF00892.15 KXX79378.1 - 0.08 12.9 5.4 0.12 12.4 1.0 2.2 2 0 0 2 2 2 0 EamA-like transporter family Sld5 PF05916.6 KXX79379.1 - 2e-15 57.0 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 KXX79380.1 - 4.7e-40 135.6 0.1 8e-40 134.9 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KXX79380.1 - 3.1e-31 107.4 1.1 5.1e-31 106.7 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.11 KXX79381.1 - 2.1e-27 95.7 49.2 2.6e-26 92.1 34.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Pribosyltran PF00156.22 KXX79382.1 - 1.6e-18 66.5 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 KXX79382.1 - 2.9e-17 62.4 3.6 7.7e-17 61.0 2.5 1.8 1 0 0 1 1 1 1 FAD binding domain UPRTase PF14681.1 KXX79382.1 - 0.0001 21.5 0.1 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.1 KXX79382.1 - 0.0021 17.8 0.0 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain BBE PF08031.7 KXX79382.1 - 0.0024 17.7 0.0 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like TRAPPC10 PF12584.3 KXX79382.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 MoCo_carrier PF12694.2 KXX79382.1 - 0.072 12.5 0.1 0.26 10.7 0.0 1.9 1 1 1 2 2 2 0 Putative molybdenum carrier RrnaAD PF00398.15 KXX79382.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PRTase_2 PF15609.1 KXX79382.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase P-mevalo_kinase PF04275.9 KXX79382.1 - 0.31 10.7 0.0 0.55 9.9 0.0 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase FAD_binding_3 PF01494.14 KXX79383.1 - 1.4e-15 57.2 0.9 1.3e-14 54.0 0.6 2.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KXX79383.1 - 0.0017 17.2 0.0 0.0041 16.0 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase HET PF06985.6 KXX79384.1 - 2.2e-33 115.3 0.2 3.2e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3761 PF12587.3 KXX79385.1 - 0.0023 17.9 0.3 0.0028 17.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3761) Pterin_4a PF01329.14 KXX79385.1 - 0.08 12.7 0.8 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase MDMPI_C PF07398.6 KXX79385.1 - 3.4 8.3 5.5 4.1 8.0 3.8 1.3 1 1 0 1 1 1 0 MDMPI C-terminal domain DUF3328 PF11807.3 KXX79386.1 - 2e-46 158.4 1.7 2.3e-46 158.2 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sulfate_transp PF00916.15 KXX79387.1 - 9.3e-54 182.3 1.9 1.8e-53 181.3 1.3 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX79387.1 - 3.7e-27 93.7 3.3 1.4e-26 91.9 2.3 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KXX79387.1 - 7.9e-17 60.7 0.0 1.9e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 KXX79387.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.9 1 1 0 1 1 1 1 STAS domain PepSY_TM_3 PF13706.1 KXX79387.1 - 4 6.9 12.0 7.6 6.0 1.4 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3636 PF12331.3 KXX79389.1 - 2.9e-43 146.9 0.0 6e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) HTH_IclR PF09339.5 KXX79389.1 - 0.12 11.9 3.3 0.29 10.7 2.3 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF287 PF03384.9 KXX79389.1 - 4.6 7.4 7.3 0.73 10.0 0.0 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Histone_HNS PF00816.16 KXX79389.1 - 5 7.7 9.2 64 4.1 0.0 2.6 2 0 0 2 2 2 0 H-NS histone family CTP_transf_1 PF01148.15 KXX79390.1 - 4.3e-78 262.5 28.5 5.3e-78 262.2 19.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 KXX79391.1 - 1.4e-69 233.9 0.1 2.9e-69 233.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX79391.1 - 2.8e-40 136.5 0.2 6e-40 135.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain EF-hand_10 PF14788.1 KXX79391.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 EF hand Glyco_hydro_cc PF11790.3 KXX79392.1 - 2.8e-68 229.9 0.1 3.2e-68 229.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 KXX79392.1 - 0.0055 16.3 0.2 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain KR PF08659.5 KXX79394.1 - 5.8e-55 185.7 1.8 1.2e-53 181.4 0.0 3.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KXX79394.1 - 8.3e-48 162.4 0.5 1.2e-45 155.4 0.0 3.4 4 0 0 4 4 3 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KXX79394.1 - 1.1e-28 99.8 0.0 2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KXX79394.1 - 5e-18 65.3 0.0 1.4e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 KXX79394.1 - 1.3e-12 47.5 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 KXX79394.1 - 1.5e-12 47.5 0.0 5.6e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79394.1 - 1.6e-10 41.3 0.0 8.3e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KXX79394.1 - 3.5e-10 39.7 0.0 6.8e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 KXX79394.1 - 4.3e-10 39.3 0.0 9.1e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79394.1 - 3.1e-08 34.1 0.0 3.1e-07 30.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79394.1 - 2e-07 30.3 0.0 4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KXX79394.1 - 9.1e-05 22.6 0.1 0.00025 21.2 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KXX79394.1 - 0.0011 17.6 0.0 1.1 7.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 KXX79394.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase HTH_38 PF13936.1 KXX79394.1 - 0.015 14.8 0.1 9.4 5.8 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain NodS PF05401.6 KXX79394.1 - 0.034 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) adh_short_C2 PF13561.1 KXX79394.1 - 0.041 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AATase PF07247.7 KXX79395.1 - 3.5e-21 75.3 0.0 4.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 KXX79395.1 - 0.052 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DNase_NucA_NucB PF14040.1 KXX79398.1 - 1.7e-28 99.0 0.1 2.9e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Toxin_21 PF08091.6 KXX79398.1 - 2.7 7.7 6.1 18 5.1 0.2 2.4 2 0 0 2 2 2 0 Spider insecticidal peptide AIG1 PF04548.11 KXX79400.1 - 1.1e-10 41.0 0.1 4.7e-10 38.9 0.0 1.8 1 1 1 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 KXX79400.1 - 1.1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KXX79400.1 - 0.0024 18.6 1.1 0.01 16.6 0.8 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KXX79400.1 - 0.0048 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KXX79400.1 - 0.0052 17.0 5.4 0.089 13.0 3.7 2.6 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 KXX79400.1 - 0.0064 15.7 1.2 0.12 11.6 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit TRF PF08558.5 KXX79400.1 - 0.0065 15.8 0.0 0.019 14.3 0.0 1.6 1 1 1 2 2 2 1 Telomere repeat binding factor (TRF) Dynamin_N PF00350.18 KXX79400.1 - 0.015 15.0 4.7 1.7 8.4 0.1 3.0 2 2 1 3 3 3 0 Dynamin family AAA_33 PF13671.1 KXX79400.1 - 0.053 13.3 0.8 0.14 11.9 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KXX79400.1 - 0.056 13.6 2.7 0.32 11.1 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KXX79400.1 - 0.069 12.5 1.6 2.8 7.3 0.4 2.7 2 1 0 3 3 3 0 SRP54-type protein, GTPase domain FeoB_N PF02421.13 KXX79400.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 KXX79400.1 - 0.084 13.1 3.5 0.13 12.6 0.1 2.7 1 1 1 3 3 3 0 AAA domain UPF0079 PF02367.12 KXX79400.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 YlqD PF11068.3 KXX79400.1 - 0.27 11.2 5.5 0.084 12.9 1.4 1.9 2 0 0 2 2 2 0 YlqD protein CorA PF01544.13 KXX79400.1 - 0.61 9.0 5.4 0.15 11.0 1.4 1.7 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF87 PF01935.12 KXX79400.1 - 0.86 9.3 8.2 6.1 6.5 5.7 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF87 Cep57_MT_bd PF06657.8 KXX79400.1 - 2.1 8.3 5.3 0.95 9.4 0.5 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 cwf21 PF08312.7 KXX79400.1 - 2.5 8.0 6.0 9.1 6.2 0.1 3.4 3 2 0 3 3 3 0 cwf21 domain M PF02370.11 KXX79400.1 - 3.4 8.3 6.9 5.1 7.7 1.2 2.9 2 0 0 2 2 2 0 M protein repeat AAA_23 PF13476.1 KXX79400.1 - 4.9 7.4 11.3 1.1e+02 3.0 7.8 2.3 1 1 0 1 1 1 0 AAA domain DUF3328 PF11807.3 KXX79402.1 - 4.5e-32 111.5 0.0 5.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Transferase PF02458.10 KXX79403.1 - 1.2e-25 89.9 0.0 1.9e-25 89.2 0.0 1.2 1 1 0 1 1 1 1 Transferase family Cutinase PF01083.17 KXX79404.1 - 6.1e-53 179.1 6.1 7e-53 178.9 4.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KXX79404.1 - 8e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KXX79404.1 - 0.00028 20.5 0.1 0.00064 19.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX79404.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79404.1 - 0.052 13.3 0.5 0.12 12.1 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 KXX79404.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) p450 PF00067.17 KXX79405.1 - 3.8e-60 203.7 0.0 5.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KXX79408.1 - 6.9e-08 31.4 0.7 4.6e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79408.1 - 5.1e-07 29.4 8.9 7.9e-07 28.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.13 KXX79408.1 - 0.023 14.2 2.7 0.042 13.3 1.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) p450 PF00067.17 KXX79409.1 - 1.3e-48 165.6 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 KXX79410.1 - 6.7e-35 120.5 0.1 8.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX79410.1 - 4.5e-05 23.4 1.9 7.5e-05 22.7 1.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79410.1 - 4.8e-05 23.1 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX79410.1 - 0.0094 15.1 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KXX79410.1 - 0.013 14.7 1.3 0.6 9.3 0.1 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S15 PF02129.13 KXX79410.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 KXX79410.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 KXX79410.1 - 0.052 12.9 1.7 1.4 8.2 1.2 2.1 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 KXX79410.1 - 0.064 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 KXX79410.1 - 0.16 10.8 0.1 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) GTP_cyclohydroI PF01227.17 KXX79411.1 - 2.3e-71 238.7 0.5 2.8e-71 238.5 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KXX79411.1 - 0.00032 20.5 0.1 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 QueF-like protein ADP_ribosyl_GH PF03747.9 KXX79412.1 - 3.7e-64 217.2 6.6 4.3e-64 217.0 4.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4360 PF14273.1 KXX79413.1 - 1.4e-54 184.5 0.5 1.6e-54 184.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Aldedh PF00171.17 KXX79414.1 - 1.1e-140 469.0 0.0 1.3e-140 468.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 KXX79414.1 - 0.012 15.2 0.1 0.032 13.8 0.0 1.7 1 1 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Amidohydro_2 PF04909.9 KXX79415.1 - 6.5e-41 140.6 1.5 8.7e-41 140.2 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX79417.1 - 1.5e-42 146.3 4.8 2.1e-42 145.7 3.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KXX79417.1 - 4e-10 39.3 0.0 1.2e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KXX79417.1 - 0.0062 16.6 6.3 0.021 14.8 0.1 3.3 2 2 1 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX79417.1 - 0.084 12.5 1.8 0.55 9.8 0.5 2.5 2 1 0 2 2 2 0 Amidohydrolase family Ribosomal_L44 PF00935.14 KXX79418.1 - 4.6e-35 119.4 10.6 6.2e-35 119.0 7.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 KXX79418.1 - 0.007 16.1 1.6 0.007 16.1 1.1 2.2 1 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.15 KXX79418.1 - 1.8 8.8 8.5 0.98 9.7 1.0 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 CorA PF01544.13 KXX79419.1 - 1.3e-05 24.4 0.3 2.7e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 2OG-FeII_Oxy_3 PF13640.1 KXX79420.1 - 0.032 14.7 0.2 0.064 13.7 0.1 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 KXX79421.1 - 5.2e-26 91.6 0.0 9.8e-26 90.7 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family HMG-CoA_red PF00368.13 KXX79422.1 - 3.5e-156 519.5 6.9 4.6e-156 519.1 4.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KXX79422.1 - 4.3e-47 159.6 2.3 8.1e-47 158.7 1.6 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KXX79422.1 - 2.9e-13 49.5 4.5 4.8e-12 45.5 3.1 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KXX79422.1 - 8.3e-06 24.0 1.5 1.3e-05 23.3 1.1 1.2 1 0 0 1 1 1 1 Patched family MFS_1 PF07690.11 KXX79423.1 - 3e-42 144.6 53.0 3e-42 144.6 36.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX79423.1 - 1.7e-17 63.1 2.9 1.7e-17 63.1 2.0 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KXX79423.1 - 4.2e-17 61.5 17.5 6.4e-17 60.9 12.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Herpes_gE PF02480.11 KXX79423.1 - 0.087 11.0 0.1 3.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Esterase_phd PF10503.4 KXX79424.1 - 2e-24 86.0 1.1 2.9e-24 85.5 0.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX79424.1 - 3.3e-14 52.6 0.7 5e-14 52.0 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.13 KXX79424.1 - 2.7e-12 46.1 12.4 2.7e-12 46.1 8.6 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KXX79424.1 - 1.9e-09 37.4 0.1 2.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX79424.1 - 2.9e-07 30.5 0.1 8.1e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX79424.1 - 0.00021 20.9 0.1 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KXX79424.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase COesterase PF00135.23 KXX79424.1 - 0.0083 14.8 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 KXX79424.1 - 0.016 14.6 0.2 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 KXX79424.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.9 KXX79424.1 - 0.033 13.3 0.3 0.29 10.2 0.0 2.2 1 1 2 3 3 3 0 Secretory lipase Peptidase_S15 PF02129.13 KXX79424.1 - 0.055 12.8 1.4 0.15 11.4 1.0 1.5 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AMP-binding PF00501.23 KXX79425.1 - 8.7e-78 261.5 0.0 1.6e-77 260.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KXX79425.1 - 9.5e-70 234.3 0.0 1.4e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KXX79425.1 - 1.2e-12 47.7 0.0 2.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KXX79425.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KXX79425.1 - 3.3e-10 39.1 0.1 9.2e-10 37.6 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KXX79425.1 - 7.6e-09 36.4 0.0 7.2e-08 33.2 0.0 2.8 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KXX79425.1 - 0.00051 20.0 2.6 0.0024 17.7 0.8 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KXX79425.1 - 0.0027 16.6 0.0 0.0052 15.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KXX79425.1 - 0.074 12.7 0.3 0.26 10.9 0.2 1.9 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 KXX79425.1 - 0.087 11.6 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Piwi PF02171.12 KXX79425.1 - 0.2 10.5 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Piwi domain PAP2 PF01569.16 KXX79426.1 - 1.5e-13 50.5 0.2 2.8e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily SUR7 PF06687.7 KXX79428.1 - 4.5e-27 95.0 1.5 5.7e-27 94.6 1.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF4149 PF13664.1 KXX79428.1 - 0.033 14.2 2.3 0.033 14.2 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Yip1 PF04893.12 KXX79428.1 - 0.77 9.2 18.3 0.24 10.8 9.8 1.9 2 0 0 2 2 2 0 Yip1 domain TPR_11 PF13414.1 KXX79429.1 - 1.3e-13 50.3 3.4 1.6e-06 27.6 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KXX79429.1 - 1.7e-13 49.3 3.8 9.1e-05 22.0 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat SET PF00856.23 KXX79429.1 - 2.7e-09 37.5 0.0 5.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.23 KXX79429.1 - 8.5e-09 34.6 3.5 0.032 13.8 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KXX79429.1 - 2.5e-06 27.3 0.4 0.088 12.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX79429.1 - 1.5e-05 24.4 0.9 0.05 13.3 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX79429.1 - 6.3e-05 23.2 0.9 0.78 10.1 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX79429.1 - 8e-05 22.9 1.9 0.31 11.7 0.8 4.7 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX79429.1 - 0.0035 17.4 3.5 2.4 8.5 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX79429.1 - 0.0047 16.6 0.4 0.28 11.0 0.2 3.5 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX79429.1 - 1.1 9.9 7.1 0.34 11.6 0.4 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.1 KXX79430.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX79430.1 - 4.5e-05 23.3 0.1 0.00014 21.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX79430.1 - 0.00064 19.8 0.0 0.00095 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX79430.1 - 0.032 14.0 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NACHT PF05729.7 KXX79431.1 - 2.1e-08 34.0 0.1 7.4e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KXX79431.1 - 2.3e-05 24.5 0.0 9.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KXX79431.1 - 0.00017 20.5 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Ank_2 PF12796.2 KXX79431.1 - 0.0018 18.5 0.0 0.012 15.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_17 PF13207.1 KXX79431.1 - 0.0072 17.1 0.1 0.052 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX79431.1 - 0.011 15.7 0.0 0.12 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KXX79431.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 KXX79431.1 - 0.015 15.0 0.0 0.61 9.9 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeat AAA_14 PF13173.1 KXX79431.1 - 0.11 12.3 0.1 3.3 7.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KXX79431.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KXX79431.1 - 0.19 12.0 0.0 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KXX79431.1 - 0.28 10.2 0.4 1.2 8.2 0.0 2.1 3 0 0 3 3 3 0 KaiC Pkinase PF00069.20 KXX79432.1 - 4.5e-73 245.5 0.0 7.6e-73 244.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79432.1 - 4.6e-37 127.4 0.0 9.8e-37 126.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79432.1 - 0.00015 20.8 0.4 0.49 9.2 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KXX79432.1 - 0.0097 15.6 1.0 0.045 13.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family adh_short_C2 PF13561.1 KXX79433.1 - 7.9e-15 55.2 0.4 1.4e-09 38.0 0.2 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX79433.1 - 5.4e-10 39.4 1.1 5.4e-10 39.4 0.8 2.1 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KXX79433.1 - 1.2e-07 31.3 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 KXX79433.1 - 0.00024 21.4 0.0 0.0012 19.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 KXX79433.1 - 0.00067 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 KXX79433.1 - 0.0018 18.8 0.3 0.0067 17.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain B12-binding PF02310.14 KXX79433.1 - 0.012 15.4 0.5 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 B12 binding domain NAD_binding_4 PF07993.7 KXX79433.1 - 0.017 14.0 0.1 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein 3HCDH_N PF02737.13 KXX79433.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KXX79433.1 - 0.1 12.0 0.0 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_31 PF13847.1 KXX79433.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.17 KXX79434.1 - 9.5e-20 71.3 0.0 1.8e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KXX79434.1 - 3.9e-09 36.3 0.0 7.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KXX79434.1 - 0.022 15.1 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAGidase PF07555.8 KXX79435.1 - 0.06 12.2 0.1 0.079 11.8 0.1 1.3 1 1 0 1 1 1 0 beta-N-acetylglucosaminidase WSC PF01822.14 KXX79436.1 - 2e-15 56.5 7.5 3.8e-15 55.5 5.2 1.5 1 0 0 1 1 1 1 WSC domain DUF3433 PF11915.3 KXX79437.1 - 1.6e-32 111.4 19.2 2.8e-18 65.8 3.8 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_hydro_3 PF00933.16 KXX79438.1 - 1.7e-56 191.3 0.0 2.4e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX79438.1 - 2e-38 132.1 0.0 6e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX79438.1 - 2.7e-06 27.2 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.16 KXX79439.1 - 2.4e-05 24.1 9.4 2.4e-05 24.1 6.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KXX79439.1 - 0.014 15.2 11.8 0.014 15.2 8.2 1.9 2 1 0 2 2 2 0 Basic region leucine zipper Mnd1 PF03962.10 KXX79439.1 - 0.048 13.3 1.2 0.077 12.6 0.8 1.2 1 0 0 1 1 1 0 Mnd1 family SAGA-Tad1 PF12767.2 KXX79439.1 - 0.084 12.5 1.6 0.19 11.3 1.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF349 PF03993.7 KXX79439.1 - 0.14 12.2 5.8 0.27 11.4 4.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) SET PF00856.23 KXX79440.1 - 6.6e-12 46.0 0.1 3.3e-11 43.7 0.1 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.7 KXX79440.1 - 0.0011 19.3 0.1 1.5 9.2 0.0 2.3 2 0 0 2 2 2 2 SAF domain TPR_12 PF13424.1 KXX79440.1 - 0.0075 16.1 2.1 0.017 15.0 1.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2225 PF09986.4 KXX79440.1 - 0.018 14.4 0.7 0.066 12.6 0.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Hemerythrin PF01814.18 KXX79441.1 - 4.7e-11 42.9 0.3 6.4e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fungal_trans_2 PF11951.3 KXX79442.1 - 3.7e-50 170.6 1.8 4.8e-50 170.2 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79442.1 - 8.2e-08 32.0 5.8 8.2e-08 32.0 4.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 KXX79443.1 - 5.7e-41 140.3 0.1 7.6e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.7 KXX79444.1 - 2.1e-121 405.1 0.0 2.4e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KXX79444.1 - 2.8e-05 24.4 0.4 0.0068 16.8 0.0 3.1 3 1 1 4 4 4 1 Replication protein A C terminal HTH_36 PF13730.1 KXX79444.1 - 0.00078 19.5 0.0 0.0019 18.2 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_34 PF13601.1 KXX79444.1 - 0.019 15.0 0.1 0.075 13.0 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 KXX79444.1 - 0.039 13.8 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC TrmB PF01978.14 KXX79444.1 - 0.054 13.2 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MARVEL PF01284.18 KXX79445.1 - 0.00013 21.8 15.0 0.00032 20.5 10.4 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF2818 PF10993.3 KXX79445.1 - 0.16 12.5 0.3 0.16 12.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) Cytochrom_B_N PF00033.14 KXX79445.1 - 3.5 6.9 9.6 0.075 12.3 0.7 2.2 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB FxsA PF04186.8 KXX79445.1 - 3.8 7.1 7.5 1.8 8.1 2.4 2.2 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein ENTH PF01417.15 KXX79446.1 - 1e-48 164.3 0.2 1.5e-48 163.7 0.2 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KXX79446.1 - 0.00019 20.2 0.2 0.00026 19.8 0.1 1.1 1 0 0 1 1 1 1 ANTH domain GRP PF07172.6 KXX79446.1 - 0.059 13.8 19.2 0.13 12.8 13.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family BAR PF03114.13 KXX79446.1 - 0.72 9.3 5.1 17 4.8 3.8 2.2 1 1 0 1 1 1 0 BAR domain TPR_11 PF13414.1 KXX79448.1 - 5.1e-59 195.8 31.7 5.2e-18 64.4 1.5 6.6 7 0 0 7 7 6 6 TPR repeat TPR_1 PF00515.23 KXX79448.1 - 4e-44 146.4 26.4 1.8e-05 24.1 0.1 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 KXX79448.1 - 2.2e-36 120.8 23.5 5.1e-05 22.8 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KXX79448.1 - 5.8e-19 67.8 8.9 4.6e-10 39.2 0.4 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX79448.1 - 4.5e-17 60.9 6.6 1.1 10.0 0.0 9.2 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KXX79448.1 - 4.3e-16 59.1 18.5 0.00056 20.4 0.1 6.9 5 2 2 7 7 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KXX79448.1 - 6.3e-14 50.9 12.7 0.065 13.4 0.3 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX79448.1 - 6.9e-13 47.3 6.4 0.051 13.3 0.0 7.4 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX79448.1 - 3.6e-12 45.1 17.7 0.076 12.8 0.1 7.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KXX79448.1 - 1.5e-10 41.2 12.7 0.0065 16.7 0.1 6.5 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KXX79448.1 - 8e-10 38.4 0.2 0.0039 17.0 0.0 4.2 5 1 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX79448.1 - 7.6e-05 22.7 13.0 0.0023 18.0 1.3 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KXX79448.1 - 0.0012 19.1 14.5 2.2 8.9 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 KXX79448.1 - 0.0013 18.5 5.1 0.23 11.4 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX79448.1 - 0.0052 16.6 3.6 7.2 6.5 0.1 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 KXX79448.1 - 0.07 12.9 11.0 13 5.7 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 KXX79448.1 - 3 7.7 20.8 5.2 7.0 0.2 6.3 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain MFS_1 PF07690.11 KXX79449.1 - 1.7e-32 112.5 18.5 1.7e-32 112.5 12.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.4 KXX79450.1 - 5.1e-20 71.7 3.0 5.1e-20 71.7 2.1 2.3 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dicty_REP PF05086.7 KXX79450.1 - 1.1 6.9 6.3 1.5 6.4 4.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein APH PF01636.18 KXX79452.1 - 7.4e-06 25.8 0.3 1.8e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cys_rich_CWC PF14375.1 KXX79452.1 - 0.16 11.9 0.4 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich CWC EcKinase PF02958.15 KXX79452.1 - 0.19 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF2040 PF09745.4 KXX79453.1 - 8e-37 125.9 23.4 8e-37 125.9 16.2 3.6 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.10 KXX79454.1 - 2.1e-19 68.5 1.6 2.6e-19 68.2 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KXX79454.1 - 0.065 12.6 0.8 0.08 12.4 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.4 KXX79454.1 - 0.097 12.4 1.1 0.13 12.1 0.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Actin PF00022.14 KXX79455.1 - 2.2e-27 95.4 0.0 2.3e-18 65.8 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KXX79455.1 - 0.022 13.3 0.0 0.47 8.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein PI-PLC-X PF00388.14 KXX79456.1 - 5.9e-62 207.3 0.0 8.7e-62 206.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KXX79456.1 - 2.5e-39 133.8 0.1 1e-38 131.9 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain DUF4451 PF14616.1 KXX79457.1 - 3.9e-35 120.3 0.5 6.9e-35 119.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF605 PF04652.11 KXX79458.1 - 1.8 7.9 20.0 2.3 7.5 13.9 1.1 1 0 0 1 1 1 0 Vta1 like Iso_dh PF00180.15 KXX79459.1 - 1.3e-111 372.9 0.0 2e-75 253.9 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 KXX79460.1 - 1.6e-09 37.3 7.2 2.5e-09 36.6 5.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KXX79460.1 - 0.016 14.4 3.9 0.026 13.8 2.7 1.3 1 0 0 1 1 1 0 PHD-finger PNRC PF15365.1 KXX79461.1 - 0.00015 21.6 6.9 0.00015 21.6 4.8 5.2 5 2 0 5 5 5 2 Proline-rich nuclear receptor coactivator Gti1_Pac2 PF09729.4 KXX79462.1 - 1.4e-41 142.2 0.1 1.4e-41 142.2 0.0 2.7 2 2 0 2 2 2 1 Gti1/Pac2 family GIDA_assoc_3 PF13932.1 KXX79463.1 - 2.1e-18 66.1 0.0 1.6e-17 63.3 0.0 2.2 3 0 0 3 3 3 1 GidA associated domain 3 CorA PF01544.13 KXX79464.1 - 2.8e-44 151.2 0.0 4.3e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 KXX79465.1 - 2e-29 101.1 0.1 2.6e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) SyrA PF11089.3 KXX79465.1 - 0.74 9.6 4.8 2.1 8.1 0.9 2.1 2 0 0 2 2 2 0 Exopolysaccharide production repressor DUF2648 PF10855.3 KXX79465.1 - 8.4 5.9 7.5 10 5.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) zf-rbx1 PF12678.2 KXX79466.1 - 4.1e-35 119.7 13.5 5e-35 119.4 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KXX79466.1 - 4e-17 61.8 9.8 5.2e-17 61.4 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KXX79466.1 - 4.7e-07 29.5 11.8 3.1e-06 26.9 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KXX79466.1 - 0.0014 18.2 11.6 0.025 14.2 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX79466.1 - 0.0026 17.3 9.4 0.37 10.4 6.7 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX79466.1 - 0.049 13.6 12.5 0.053 13.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX79466.1 - 0.55 9.9 11.8 5.3 6.8 8.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 KXX79466.1 - 0.89 9.5 9.3 4.8 7.2 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KXX79466.1 - 1.8 8.3 7.0 4.1 7.2 2.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 KXX79466.1 - 2 8.6 10.9 1.1e+02 3.0 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain Tyr-DNA_phospho PF06087.7 KXX79467.1 - 2.6e-64 217.4 0.0 3.4e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KXX79467.1 - 1.2e-05 25.0 0.0 0.00096 18.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain CDP-OH_P_transf PF01066.16 KXX79468.1 - 3.5e-16 59.3 5.5 6e-16 58.5 3.8 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase zf-Tim10_DDP PF02953.10 KXX79469.1 - 1.8e-21 75.2 1.9 2.3e-21 74.8 1.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 KXX79470.1 - 2e-20 72.5 11.4 2e-20 72.5 7.9 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KXX79470.1 - 6.4e-16 58.0 0.8 1.4e-15 57.0 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3321 PF11968.3 KXX79471.1 - 3.2e-94 314.6 0.0 3.9e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KXX79471.1 - 0.00074 19.2 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.1 KXX79472.1 - 5e-31 108.2 0.0 5.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX79472.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 KXX79472.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.20 KXX79473.1 - 7.5e-59 198.9 0.0 1.2e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79473.1 - 1.2e-33 116.2 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79473.1 - 6.7e-14 51.5 0.0 9.1e-11 41.2 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Aa_trans PF01490.13 KXX79474.1 - 2.1e-59 201.0 29.5 2.7e-59 200.6 20.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DEAD PF00270.24 KXX79475.1 - 2.6e-31 108.3 0.0 4.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX79475.1 - 2.7e-18 65.6 0.0 5.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX79475.1 - 6e-05 22.9 0.0 0.00014 21.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KXX79475.1 - 0.0015 17.4 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CorA PF01544.13 KXX79476.1 - 2.6e-05 23.4 4.0 2.6e-05 23.4 2.8 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.1 KXX79476.1 - 0.039 14.0 2.6 0.09 12.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) BatD PF13584.1 KXX79476.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF3301 PF11743.3 KXX79476.1 - 0.11 11.9 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) His_Phos_1 PF00300.17 KXX79477.1 - 1.5e-23 83.5 0.0 2.6e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1762 PF08574.5 KXX79479.1 - 0.005 17.2 12.1 0.005 17.2 8.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) RabGAP-TBC PF00566.13 KXX79481.1 - 8.4e-27 94.0 0.3 1.2e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF605 PF04652.11 KXX79481.1 - 0.59 9.4 14.3 0.99 8.7 9.9 1.3 1 0 0 1 1 1 0 Vta1 like PBD PF00786.23 KXX79482.1 - 0.0031 17.8 0.0 0.019 15.3 0.0 2.5 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.20 KXX79483.1 - 2.8e-71 239.7 0.3 5.2e-71 238.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79483.1 - 1.3e-37 129.3 0.0 2.3e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79483.1 - 4.2e-08 32.5 0.0 7.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like BAF1_ABF1 PF04684.8 KXX79483.1 - 0.46 9.2 14.6 0.66 8.7 10.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 KXX79483.1 - 1.9 6.6 39.0 2.5 6.2 27.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KXX79483.1 - 7.4 6.3 31.7 11 5.8 22.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lectin_leg-like PF03388.8 KXX79484.1 - 1.2e-66 224.0 0.0 1.6e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KXX79484.1 - 0.004 16.5 0.0 0.49 9.7 0.0 2.5 3 0 0 3 3 3 2 Legume lectin domain ATG27 PF09451.5 KXX79484.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Abhydrolase_5 PF12695.2 KXX79485.1 - 2.7e-07 30.4 0.5 4.5e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_12 PF13424.1 KXX79486.1 - 2.3e-22 78.7 8.3 4.8e-07 29.6 0.0 5.0 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KXX79486.1 - 7.3e-10 38.4 14.7 0.0066 16.3 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX79486.1 - 2.1e-09 36.5 4.0 0.48 10.1 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX79486.1 - 3.4e-09 36.2 4.6 0.025 14.2 0.0 5.0 3 1 3 6 6 6 4 TPR repeat TPR_2 PF07719.12 KXX79486.1 - 1.2e-06 28.0 11.3 1.5 8.9 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX79486.1 - 1.2e-05 24.7 2.9 11 6.1 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX79486.1 - 5.3e-05 22.7 0.1 30 4.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX79486.1 - 0.00021 21.5 1.3 3.3 8.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX79486.1 - 0.042 14.0 1.9 77 3.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX79486.1 - 0.33 11.6 10.8 9.3 7.0 0.0 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 KXX79487.1 - 5.2e-37 127.3 67.2 3.7e-24 85.1 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX79487.1 - 0.00083 17.8 12.6 0.00083 17.8 8.7 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 KXX79487.1 - 0.023 14.4 7.9 2.9 7.7 0.0 3.9 4 0 0 4 4 4 0 MFS_1 like family PNP_UDP_1 PF01048.15 KXX79488.1 - 2.4e-11 43.0 0.1 5.3e-11 41.9 0.1 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Ank PF00023.25 KXX79489.1 - 1.5e-22 78.1 0.0 1.4e-07 30.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KXX79489.1 - 3.9e-20 71.9 0.0 7.8e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX79489.1 - 9.3e-16 57.8 0.5 1.1e-07 32.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79489.1 - 2.7e-13 48.7 0.0 0.00027 20.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX79489.1 - 1.3e-12 47.4 1.3 6.9e-08 32.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HTH_15 PF12324.3 KXX79489.1 - 0.0077 15.8 0.0 0.028 14.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase XPC-binding PF09280.6 KXX79489.1 - 0.15 11.5 1.2 5.5 6.5 0.1 2.6 2 0 0 2 2 2 0 XPC-binding domain Yippee-Mis18 PF03226.9 KXX79490.1 - 8.4e-20 70.6 0.0 1.2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Peptidase_M20 PF01546.23 KXX79491.1 - 2.6e-32 111.8 0.0 5.3e-32 110.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KXX79491.1 - 2.8e-14 52.8 0.0 4.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.18 KXX79492.1 - 1.9e-05 24.5 0.0 7.7e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-RING_2 PF13639.1 KXX79493.1 - 2.1e-15 56.2 5.3 2.1e-15 56.2 3.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX79493.1 - 1.5e-09 37.3 12.4 1.2e-07 31.2 3.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX79493.1 - 6.2e-09 35.8 1.0 6.2e-09 35.8 0.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KXX79493.1 - 1e-07 31.8 16.1 7.9e-07 28.9 4.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX79493.1 - 2.3e-07 30.4 13.0 2.1e-06 27.3 2.8 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX79493.1 - 2.1e-06 27.2 13.2 2.3e-05 23.9 3.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX79493.1 - 0.0017 18.1 0.8 0.0017 18.1 0.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KXX79493.1 - 0.0041 16.6 3.1 0.015 14.8 2.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HypA PF01155.14 KXX79493.1 - 0.0066 16.1 1.0 0.0066 16.1 0.7 2.0 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 KXX79493.1 - 0.086 12.4 12.9 1 8.9 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 KXX79493.1 - 0.13 12.0 3.6 3.5 7.4 0.3 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain FdhE PF04216.7 KXX79493.1 - 0.22 11.2 4.8 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation PHD PF00628.24 KXX79493.1 - 0.24 11.1 12.7 0.67 9.7 2.8 2.8 2 1 1 3 3 3 0 PHD-finger Prok-RING_1 PF14446.1 KXX79493.1 - 0.25 11.0 11.7 1.3 8.7 0.2 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.9 KXX79493.1 - 0.35 10.3 5.6 0.13 11.7 0.3 2.5 3 0 0 3 3 2 0 Rad50 zinc hook motif Cytochrom_CIII PF02085.11 KXX79493.1 - 0.8 9.8 7.1 0.091 12.8 0.8 2.2 2 0 0 2 2 2 0 Class III cytochrome C family Suf PF05843.9 KXX79493.1 - 0.98 9.0 9.2 0.41 10.3 2.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DZR PF12773.2 KXX79493.1 - 1.9 8.3 10.4 0.47 10.3 0.9 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 KXX79493.1 - 3.4 7.7 8.2 1.3 9.1 2.5 2.4 2 0 0 2 2 2 0 zinc-finger PAT1 PF09770.4 KXX79493.1 - 5.3 5.1 24.2 7.5 4.6 16.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_6 PF14835.1 KXX79493.1 - 9.9 6.0 7.3 2 8.2 1.6 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Amidohydro_3 PF07969.6 KXX79498.1 - 1.9e-29 103.1 0.3 4.9e-29 101.7 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KXX79498.1 - 7.8e-06 25.6 0.0 2.5e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase dCMP_cyt_deam_1 PF00383.17 KXX79499.1 - 1.8e-07 30.7 0.1 2.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 3D PF06725.6 KXX79499.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 3D domain LmjF365940-deam PF14421.1 KXX79499.1 - 0.11 11.8 0.6 7.7 5.8 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.11 KXX79500.1 - 4.3e-25 88.1 29.3 1.6e-21 76.3 4.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.8 KXX79501.1 - 4.2e-31 106.1 5.2 4.9e-31 105.9 3.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KXX79501.1 - 0.069 12.9 3.8 0.056 13.2 1.7 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_S28 PF05577.7 KXX79502.1 - 2e-47 161.7 0.0 2.9e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Fungal_trans PF04082.13 KXX79504.1 - 4.5e-15 55.2 0.0 6.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX79504.1 - 2.8e-08 33.5 11.4 4.4e-08 32.9 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KXX79505.1 - 4.4e-27 94.2 1.0 1.8e-19 69.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79505.1 - 7e-26 88.7 4.2 1.3e-07 31.0 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KXX79505.1 - 3.5e-23 81.5 0.2 9.9e-11 41.8 0.0 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79505.1 - 6.6e-21 72.3 0.5 1.5e-05 24.7 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KXX79505.1 - 1.1e-16 60.4 0.1 5.6e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) pRN1_helical PF13010.1 KXX79505.1 - 0.034 13.7 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Primase helical domain FAD_binding_3 PF01494.14 KXX79506.1 - 3.9e-15 55.7 0.4 3e-09 36.4 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX79506.1 - 3.2e-10 39.4 0.1 3.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX79506.1 - 1.2e-08 35.0 0.1 3.6e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX79506.1 - 4.3e-08 32.4 1.1 5.3e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KXX79506.1 - 3.1e-07 30.3 0.1 7.2e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX79506.1 - 3.8e-07 28.9 0.3 4.6e-06 25.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KXX79506.1 - 2.5e-06 26.6 0.0 4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KXX79506.1 - 1e-05 24.8 0.8 1.4e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX79506.1 - 2.8e-05 24.4 0.3 0.00073 19.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KXX79506.1 - 0.00029 20.0 0.1 0.43 9.5 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KXX79506.1 - 0.0005 18.8 0.2 0.59 8.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KXX79506.1 - 0.00077 19.5 0.2 0.0017 18.4 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX79506.1 - 0.0034 16.3 0.3 0.017 14.0 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KXX79506.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KXX79506.1 - 0.013 14.6 0.3 0.036 13.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 KXX79506.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KXX79506.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KXX79506.1 - 0.054 13.1 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KXX79506.1 - 0.054 13.4 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding FMO-like PF00743.14 KXX79506.1 - 0.066 11.3 0.1 0.094 10.8 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Response_reg PF00072.19 KXX79508.1 - 4.6e-27 94.2 0.1 9.3e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KXX79508.1 - 3.2e-25 87.9 0.0 7.9e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KXX79508.1 - 4.7e-19 68.1 0.1 9.3e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KXX79508.1 - 8.6e-15 54.9 0.0 9.3e-14 51.6 0.0 2.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 KXX79508.1 - 4.1e-07 29.7 0.0 1.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 KXX79508.1 - 8.5e-06 25.7 0.0 0.006 16.6 0.0 2.6 2 0 0 2 2 2 2 PAS fold CAF-1_p150 PF11600.3 KXX79509.1 - 0.26 10.6 11.7 0.35 10.2 8.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIIC_sub6 PF10419.4 KXX79510.1 - 2.4e-13 49.2 0.0 4.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 KXX79511.1 - 1.2e-10 40.0 0.1 2.4e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 KXX79511.1 - 0.001 17.7 0.4 0.0097 14.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1302) DUF1996 PF09362.5 KXX79512.1 - 1.4e-85 286.6 0.5 1.7e-85 286.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_11 PF00457.12 KXX79513.1 - 9e-78 259.8 20.6 1.2e-77 259.4 14.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KXX79513.1 - 1.4e-12 47.0 17.8 1.4e-12 47.0 12.3 3.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KXX79513.1 - 0.43 10.6 8.8 0.78 9.8 6.1 1.5 1 0 0 1 1 1 0 Toxin 7 ODC_AZ PF02100.12 KXX79514.1 - 1.4e-27 95.3 0.0 2e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.16 KXX79515.1 - 3.9e-49 166.9 0.1 1.3e-48 165.2 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KXX79515.1 - 2.2e-25 89.2 0.0 3.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KXX79515.1 - 1.4e-08 34.5 0.0 5.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KXX79515.1 - 7.3e-07 28.9 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 KXX79515.1 - 0.015 14.1 0.0 0.034 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 KXX79515.1 - 0.057 12.8 0.1 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 MIF PF01187.13 KXX79516.1 - 1.7e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) mono-CXXC PF15626.1 KXX79516.1 - 0.087 12.7 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 single CXXC unit Gtr1_RagA PF04670.7 KXX79517.1 - 5.7e-71 238.3 0.1 7.2e-71 237.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KXX79517.1 - 0.00094 19.6 0.0 0.0076 16.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX79517.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC2_membrane_4 PF12730.2 KXX79518.1 - 1.4 8.0 7.1 9.8 5.2 4.9 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein Tim17 PF02466.14 KXX79519.1 - 4.8e-29 101.0 2.4 6e-29 100.6 1.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family XhlA PF10779.4 KXX79520.1 - 0.00069 19.4 1.5 0.01 15.7 1.0 2.2 1 1 0 1 1 1 1 Haemolysin XhlA HSBP1 PF06825.7 KXX79520.1 - 0.00093 18.7 1.9 0.0099 15.4 1.3 2.5 1 1 0 1 1 1 1 Heat shock factor binding protein 1 UPF0184 PF03670.8 KXX79520.1 - 0.0013 18.8 0.4 0.013 15.6 0.3 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0184) EzrA PF06160.7 KXX79520.1 - 0.002 16.4 0.1 0.0026 16.0 0.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Vac_Fusion PF02346.11 KXX79520.1 - 0.0026 17.1 2.4 0.042 13.2 1.9 2.6 2 1 0 2 2 2 1 Chordopoxvirus fusion protein NPV_P10 PF05531.7 KXX79520.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.1 KXX79520.1 - 0.0072 16.4 1.0 3.2 7.9 0.2 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) Tropomyosin PF00261.15 KXX79520.1 - 0.011 14.8 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin Hpt PF01627.18 KXX79520.1 - 0.014 15.3 0.4 0.51 10.3 0.1 2.2 1 1 1 2 2 2 0 Hpt domain Nsp1_C PF05064.8 KXX79520.1 - 0.017 14.7 0.1 0.043 13.4 0.0 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 KXX79520.1 - 0.018 14.9 0.1 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 KXX79520.1 - 0.018 14.7 0.1 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KXX79520.1 - 0.019 14.7 0.1 0.041 13.7 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KXX79520.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein MtrG PF04210.8 KXX79520.1 - 0.025 14.2 0.6 2.1 8.0 0.1 2.4 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ADIP PF11559.3 KXX79520.1 - 0.027 14.3 0.3 0.11 12.3 0.2 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YvrJ PF12841.2 KXX79520.1 - 0.029 13.6 2.2 5.5 6.3 0.0 3.1 3 1 0 3 3 3 0 YvrJ protein family COG5 PF10392.4 KXX79520.1 - 0.034 14.1 0.1 9 6.2 0.0 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 KXX79520.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) RmuC PF02646.11 KXX79520.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 RmuC family Allexi_40kDa PF05549.6 KXX79520.1 - 0.038 13.2 0.2 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1978 PF09321.5 KXX79520.1 - 0.051 13.0 0.2 0.072 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Snapin_Pallidin PF14712.1 KXX79520.1 - 0.061 13.6 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.7 KXX79520.1 - 0.065 12.9 0.1 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Laminin Domain II Osmo_CC PF08946.5 KXX79520.1 - 0.069 13.1 0.2 0.069 13.1 0.1 2.7 3 1 0 3 3 1 0 Osmosensory transporter coiled coil PilJ PF13675.1 KXX79520.1 - 0.083 13.2 0.3 1.3 9.4 0.1 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Occludin_ELL PF07303.8 KXX79520.1 - 0.088 13.5 0.3 0.35 11.6 0.1 2.1 2 1 0 2 2 1 0 Occludin homology domain MscS_porin PF12795.2 KXX79520.1 - 0.088 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain vATP-synt_E PF01991.13 KXX79520.1 - 0.09 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit FH2 PF02181.18 KXX79520.1 - 0.095 11.5 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain BLOC1_2 PF10046.4 KXX79520.1 - 0.1 12.7 0.1 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynactin_p22 PF07426.6 KXX79520.1 - 0.11 11.8 0.0 6.1 6.0 0.0 2.2 1 1 1 2 2 2 0 Dynactin subunit p22 Viral_P18 PF04521.8 KXX79520.1 - 0.13 11.7 0.4 11 5.4 0.0 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2730 PF10805.3 KXX79520.1 - 0.15 11.8 0.5 1.3 8.8 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2428 PF10350.4 KXX79522.1 - 8.8e-68 228.0 0.1 2.3e-67 226.7 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KXX79522.1 - 2.4e-05 24.0 15.4 3 8.1 0.1 7.7 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KXX79522.1 - 0.00018 21.7 1.8 0.28 11.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 KXX79522.1 - 0.48 10.9 5.8 20 5.8 0.1 5.3 5 0 0 5 5 5 0 HEAT-like repeat YEATS PF03366.11 KXX79523.1 - 2.9e-29 100.6 0.3 4.4e-29 100.0 0.2 1.3 1 0 0 1 1 1 1 YEATS family DUF2404 PF10296.4 KXX79524.1 - 0.0008 19.4 0.0 0.0029 17.7 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 KXX79525.1 - 6e-42 143.7 0.0 7.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.13 KXX79526.1 - 6.5e-39 133.9 6.5 6.5e-39 133.9 4.5 2.9 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KXX79526.1 - 0.0015 17.3 7.9 0.0015 17.3 5.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2975 PF11188.3 KXX79526.1 - 1.6 8.4 15.3 0.17 11.5 1.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) Catalase PF00199.14 KXX79527.1 - 8.5e-160 531.6 0.2 1.1e-159 531.3 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KXX79527.1 - 3.6e-21 74.7 0.1 6.7e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF3635 PF12330.3 KXX79528.1 - 4.2e-06 26.7 0.0 1.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 KXX79529.1 - 1e-100 336.7 0.4 1.2e-100 336.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.7 KXX79529.1 - 0.074 13.1 0.1 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF77 PF01910.12 KXX79530.1 - 2.2e-32 110.5 0.3 2.5e-32 110.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 KXX79530.1 - 0.00016 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PGK PF00162.14 KXX79530.1 - 0.0017 17.0 0.1 0.002 16.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Acid_PPase PF12689.2 KXX79530.1 - 0.0042 16.7 0.0 0.0074 15.9 0.0 1.4 1 1 0 1 1 1 1 Acid Phosphatase DUF2834 PF11196.3 KXX79531.1 - 0.0026 17.8 3.6 0.12 12.5 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2834) PepSY_TM_2 PF13703.1 KXX79531.1 - 0.2 11.8 6.0 1 9.5 0.2 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix Arf PF00025.16 KXX79532.1 - 8.9e-40 135.7 0.0 1.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KXX79532.1 - 2e-15 56.3 0.0 1.5e-10 40.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KXX79532.1 - 7.2e-09 35.1 0.0 8.4e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KXX79532.1 - 4.2e-07 29.4 0.0 1e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 KXX79532.1 - 6.9e-07 28.6 0.0 1.5e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KXX79532.1 - 4.9e-05 23.8 0.0 0.00016 22.1 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KXX79532.1 - 5.1e-05 22.8 0.0 0.00015 21.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX79532.1 - 0.0044 16.9 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L29e PF01779.12 KXX79533.1 - 1.6e-23 82.2 9.3 2.5e-23 81.6 6.4 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.12 KXX79534.1 - 4.1e-11 42.5 0.2 7.6e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX79534.1 - 5.2e-06 26.5 0.3 1.1e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KXX79534.1 - 0.02 14.7 0.3 0.058 13.3 0.2 1.7 1 0 0 1 1 1 0 IGR protein motif DUF1031 PF06275.6 KXX79534.1 - 0.19 11.7 0.2 0.44 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Peptidase_C2 PF00648.16 KXX79535.1 - 1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KXX79535.1 - 0.097 12.5 4.7 0.18 11.7 3.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 KXX79536.1 - 3.7e-56 186.8 1.1 5.2e-19 67.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nol1_Nop2_Fmu PF01189.12 KXX79537.1 - 8.7e-19 67.9 0.0 8.3e-14 51.6 0.0 2.2 1 1 0 2 2 2 2 NOL1/NOP2/sun family Dicty_REP PF05086.7 KXX79537.1 - 4 5.0 4.3 5.6 4.5 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EBP PF05241.7 KXX79538.1 - 6.1e-59 198.3 3.8 7.6e-59 198.0 2.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein TPR_11 PF13414.1 KXX79539.1 - 3.1e-20 71.5 25.6 3.7e-06 26.4 0.4 8.0 8 0 0 8 8 8 5 TPR repeat TPR_1 PF00515.23 KXX79539.1 - 2.4e-09 36.4 13.7 1.7 8.3 0.2 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KXX79539.1 - 7.9e-09 35.3 22.7 0.0026 17.6 0.1 7.9 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KXX79539.1 - 9.6e-09 34.4 6.1 1.4 8.9 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX79539.1 - 1.6e-08 33.8 17.5 1.1 9.3 0.1 10.4 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX79539.1 - 3.6e-06 26.7 4.0 48 4.5 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX79539.1 - 1.1e-05 25.5 20.9 0.19 12.4 0.0 10.0 8 3 4 12 12 12 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX79539.1 - 2.4e-05 24.5 12.6 1.2 9.5 0.1 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX79539.1 - 4.8e-05 23.9 28.0 0.025 15.2 0.0 8.4 9 1 2 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX79539.1 - 0.0011 18.6 15.6 1.7 8.6 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 KXX79539.1 - 0.0067 16.5 11.2 0.29 11.2 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX79539.1 - 0.45 11.0 10.6 14 6.3 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1996 PF09362.5 KXX79540.1 - 4.5e-59 199.9 0.0 8.2e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KXX79540.1 - 4.3e-19 68.2 13.0 8.9e-19 67.2 7.4 2.4 2 0 0 2 2 2 1 WSC domain Cwf_Cwc_15 PF04889.7 KXX79541.1 - 1.1e-86 290.4 15.1 1.3e-86 290.3 10.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 KXX79541.1 - 0.017 15.1 10.3 0.024 14.6 7.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Nop53 PF07767.6 KXX79541.1 - 0.051 12.5 17.8 0.076 11.9 12.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.12 KXX79541.1 - 0.65 9.7 4.0 0.98 9.1 2.8 1.3 1 0 0 1 1 1 0 DDHD domain Nucleo_P87 PF07267.6 KXX79541.1 - 0.77 8.3 7.7 0.91 8.1 5.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.7 KXX79541.1 - 0.87 8.8 23.3 1.2 8.3 16.1 1.2 1 0 0 1 1 1 0 SDA1 DUF1509 PF07420.6 KXX79541.1 - 1.1 8.5 12.0 1.3 8.1 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Nop14 PF04147.7 KXX79541.1 - 1.4 6.7 23.5 1.7 6.4 16.3 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 KXX79541.1 - 2.4 7.3 14.3 2.6 7.1 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 KXX79541.1 - 2.4 6.0 21.7 3 5.7 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom37_C PF11801.3 KXX79541.1 - 3.7 7.3 5.4 5.8 6.7 3.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain NOA36 PF06524.7 KXX79541.1 - 7.2 5.7 10.1 10 5.2 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein OmpH PF03938.9 KXX79541.1 - 9.4 6.1 9.2 3.2 7.6 4.7 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RNase_PH PF01138.16 KXX79542.1 - 3.9e-21 75.7 0.0 6.7e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KXX79542.1 - 3.6e-07 30.0 0.0 7.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CoaE PF01121.15 KXX79544.1 - 2.4e-43 147.6 0.0 1e-42 145.5 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KXX79544.1 - 0.0011 19.7 1.0 0.0033 18.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX79544.1 - 0.0093 15.8 0.0 0.071 12.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain CcmH PF03918.9 KXX79544.1 - 0.012 14.6 1.2 0.02 13.8 0.8 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein AAA_18 PF13238.1 KXX79544.1 - 0.028 14.7 0.4 0.26 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain FixP_N PF14715.1 KXX79544.1 - 0.43 9.9 4.8 0.8 9.1 3.4 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP NAD_binding_10 PF13460.1 KXX79545.1 - 2.7e-14 53.5 0.0 6e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX79545.1 - 9.9e-07 28.4 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX79545.1 - 0.0003 19.6 0.0 0.0007 18.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KXX79545.1 - 0.0018 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KXX79545.1 - 0.002 17.0 0.0 0.061 12.2 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KXX79545.1 - 0.021 13.7 0.0 0.31 9.8 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain DUF3180 PF11377.3 KXX79545.1 - 0.12 12.1 0.7 0.23 11.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) SYF2 PF08231.7 KXX79546.1 - 6.2e-52 175.7 10.2 6.2e-52 175.7 7.1 1.7 2 0 0 2 2 2 1 SYF2 splicing factor HEAT PF02985.17 KXX79547.1 - 8.3e-06 25.4 4.7 0.034 14.2 0.3 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KXX79547.1 - 0.00025 21.2 5.4 1.1 9.6 0.0 5.3 5 0 0 5 5 5 2 HEAT repeats TraY PF05509.6 KXX79547.1 - 0.063 13.0 0.4 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 TraY domain HEAT_EZ PF13513.1 KXX79547.1 - 0.12 12.9 8.3 0.16 12.4 1.3 4.4 4 0 0 4 4 4 0 HEAT-like repeat Pkinase PF00069.20 KXX79548.1 - 4e-38 131.0 0.0 6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79548.1 - 4.4e-29 101.3 0.0 6.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX79548.1 - 0.0006 19.6 0.0 0.54 9.9 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KXX79548.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3439 PF11921.3 KXX79548.1 - 0.6 9.8 4.9 0.36 10.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1749 PF08538.5 KXX79549.1 - 3.8e-88 295.2 0.0 4.4e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KXX79549.1 - 2.2e-13 50.6 0.1 3.1e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79549.1 - 2.3e-07 30.6 0.0 5.4e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX79549.1 - 0.0051 16.3 0.0 0.02 14.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KXX79549.1 - 0.021 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 KXX79549.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 KXX79549.1 - 0.18 11.2 0.0 6.3 6.1 0.0 2.1 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.17 KXX79551.1 - 1.5e-45 155.6 0.0 2.7e-45 154.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.19 KXX79551.1 - 0.21 10.9 0.1 0.34 10.2 0.1 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain eIF-5_eIF-2B PF01873.12 KXX79552.1 - 4.3e-40 136.2 0.0 7.9e-40 135.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KXX79552.1 - 1.4e-25 89.0 0.9 1.4e-25 89.0 0.6 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3328 PF11807.3 KXX79553.1 - 4e-27 95.3 0.0 5.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3180 PF11377.3 KXX79554.1 - 0.16 11.8 0.3 0.16 11.8 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) Macoilin PF09726.4 KXX79559.1 - 0.004 15.5 0.3 0.0042 15.4 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein MRP-S31 PF15433.1 KXX79559.1 - 0.0099 15.3 1.5 0.013 14.8 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 BssS PF13991.1 KXX79559.1 - 0.036 13.7 0.7 0.13 12.0 0.2 2.1 2 0 0 2 2 2 0 BssS protein family DUF3584 PF12128.3 KXX79559.1 - 0.048 10.9 6.0 0.061 10.6 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KXX79559.1 - 0.078 12.5 1.8 0.1 12.1 1.3 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KXX79559.1 - 0.083 11.9 4.7 0.11 11.4 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KXX79559.1 - 0.13 12.0 5.8 0.19 11.4 4.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 KXX79559.1 - 0.41 10.6 14.7 2.7 7.9 0.6 2.4 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Prp19 PF08606.6 KXX79559.1 - 0.71 9.6 6.2 0.07 12.8 0.8 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like TMF_TATA_bd PF12325.3 KXX79559.1 - 1.2 8.8 9.0 12 5.6 6.2 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1635 PF07795.6 KXX79559.1 - 1.7 7.9 5.8 6.3 6.1 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) Atg14 PF10186.4 KXX79559.1 - 5.7 5.7 7.6 8.2 5.2 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BNR_2 PF13088.1 KXX79560.1 - 1.9e-05 24.0 0.1 0.0053 16.0 0.0 2.3 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KXX79560.1 - 6 7.1 5.8 3.7 7.7 0.4 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyco_hydro_3 PF00933.16 KXX79561.1 - 2.9e-60 203.8 0.0 4.2e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX79561.1 - 1.2e-36 126.3 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX79561.1 - 3.7e-06 26.7 0.0 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_1 PF00583.19 KXX79562.1 - 9.7e-05 22.3 0.0 0.00027 20.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Ank_4 PF13637.1 KXX79562.1 - 0.00057 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79562.1 - 0.00074 19.5 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 KXX79562.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX79562.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.1 KXX79562.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX79562.1 - 0.0016 18.1 0.1 0.0094 15.6 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Ank PF00023.25 KXX79562.1 - 0.0023 17.6 0.1 0.0069 16.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_CG PF14542.1 KXX79562.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KXX79562.1 - 0.12 12.5 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lectin_C PF00059.16 KXX79563.1 - 0.013 16.1 0.0 0.93 10.1 0.0 2.1 1 1 1 2 2 2 0 Lectin C-type domain Pkinase PF00069.20 KXX79567.1 - 5.8e-20 71.5 0.0 1.7e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79567.1 - 1.2e-05 24.5 0.0 0.11 11.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Esterase_phd PF10503.4 KXX79568.1 - 4e-07 29.5 0.1 1.3e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KXX79568.1 - 1.4e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KXX79568.1 - 1.5e-05 24.5 0.1 4.5e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KXX79568.1 - 2e-05 23.9 0.1 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KXX79568.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79568.1 - 0.00016 21.4 0.0 0.00024 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX79568.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 KXX79568.1 - 0.018 13.5 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Cnd1_N PF12922.2 KXX79569.1 - 2.3e-59 199.8 0.1 2.3e-59 199.8 0.1 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KXX79569.1 - 6.6e-56 188.9 0.4 1.7e-52 177.8 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KXX79569.1 - 1.2e-10 41.5 6.5 1.9e-05 24.8 0.1 6.3 5 3 2 7 7 7 3 HEAT repeats HEAT PF02985.17 KXX79569.1 - 1.4e-07 30.9 14.1 0.044 13.8 0.0 7.1 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 KXX79569.1 - 2.1e-06 28.0 5.5 0.02 15.3 0.2 5.6 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 KXX79569.1 - 0.00024 19.5 2.7 0.024 12.9 0.1 3.5 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 KXX79569.1 - 0.00044 19.3 1.9 0.0024 16.9 0.1 3.1 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 KXX79569.1 - 0.00069 19.4 0.0 0.75 9.7 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 KXX79569.1 - 0.061 13.2 0.1 6.9 6.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ald_Xan_dh_C2 PF02738.13 KXX79569.1 - 0.096 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Pkinase PF00069.20 KXX79570.1 - 3.1e-41 141.2 0.0 1.8e-37 128.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79570.1 - 1.2e-13 50.7 0.0 8.5e-08 31.5 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 KXX79570.1 - 0.00069 19.4 0.0 0.066 12.9 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX79570.1 - 0.0025 16.8 0.0 0.54 9.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Helicase_C_2 PF13307.1 KXX79571.1 - 5.6e-57 192.3 0.0 1.4e-56 190.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KXX79571.1 - 6.6e-46 155.8 0.0 1.3e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KXX79571.1 - 0.0063 16.3 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit BetR PF08667.5 KXX79571.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 BetR domain SNF2_N PF00176.18 KXX79571.1 - 0.091 11.5 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.1 KXX79571.1 - 0.15 12.2 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain HET PF06985.6 KXX79572.1 - 1.6e-19 70.4 0.0 2.6e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KXX79573.1 - 1.1e-19 70.9 0.0 2.2e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GRIM-19 PF06212.7 KXX79574.1 - 3.2e-22 78.6 0.0 6.2e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.13 KXX79575.1 - 5.4e-27 94.4 0.1 2.9e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KXX79575.1 - 2.9e-06 27.0 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KXX79575.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 KXX79575.1 - 0.0081 15.7 0.0 4.8 6.9 0.0 2.9 1 1 1 2 2 2 2 Biotin-requiring enzyme IncA PF04156.9 KXX79575.1 - 1.6 8.2 8.9 1.1 8.8 3.2 2.6 2 0 0 2 2 2 0 IncA protein GRAM PF02893.15 KXX79576.1 - 1.4e-26 91.8 0.1 6.2e-15 54.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KXX79576.1 - 2.9e-25 88.6 0.0 7.7e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KXX79576.1 - 3.7e-10 39.9 0.0 9.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KXX79576.1 - 0.00017 21.5 0.2 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 KXX79576.1 - 0.00034 19.3 0.0 0.0014 17.3 0.0 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 KXX79576.1 - 0.0028 17.5 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KXX79576.1 - 0.004 17.4 0.8 0.022 15.0 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain E1-E2_ATPase PF00122.15 KXX79577.1 - 9.2e-51 172.0 4.9 1.5e-50 171.3 3.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX79577.1 - 7.2e-28 98.4 0.3 1.4e-27 97.5 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KXX79577.1 - 1.7e-13 51.1 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KXX79577.1 - 6.9e-05 22.9 1.3 0.00021 21.3 0.0 2.5 3 0 0 3 3 3 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KXX79577.1 - 0.00042 19.9 0.6 0.01 15.4 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ferric_reduct PF01794.14 KXX79579.1 - 1 9.4 11.6 2.7 8.1 8.1 1.7 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Glyco_hydro_2_N PF02837.13 KXX79581.1 - 1.5e-36 125.5 0.2 9.2e-36 122.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KXX79581.1 - 8.7e-29 100.3 0.0 7.1e-28 97.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KXX79581.1 - 1e-12 48.4 0.0 2.7e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KXX79581.1 - 0.00011 22.4 0.1 0.0013 19.0 0.0 2.7 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 KXX79581.1 - 0.032 14.1 0.4 0.09 12.6 0.3 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF3632 PF12311.3 KXX79582.1 - 1.1e-29 103.6 2.5 1.4e-29 103.1 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.6 KXX79583.1 - 3e-18 66.3 0.1 4.9e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rad4 PF03835.10 KXX79585.1 - 2.5e-11 43.1 2.4 3.8e-11 42.5 1.0 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KXX79585.1 - 1.4e-07 31.6 1.3 3e-07 30.6 0.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ogr_Delta PF04606.7 KXX79585.1 - 0.12 12.1 1.6 0.27 10.9 1.1 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger YdjO PF14169.1 KXX79585.1 - 0.36 10.3 4.8 4.2 6.8 0.2 2.4 1 1 1 2 2 2 0 Cold-inducible protein YdjO DUF846 PF05832.7 KXX79586.1 - 1.1e-45 154.8 8.6 1.3e-45 154.5 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 KXX79586.1 - 0.062 13.3 8.7 0.26 11.3 0.8 2.1 2 0 0 2 2 2 0 YwiC-like protein HpcH_HpaI PF03328.9 KXX79587.1 - 4.7e-40 136.8 0.0 8.8e-40 135.9 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KXX79587.1 - 4.2e-15 55.4 0.0 9.9e-08 31.1 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Hep_59 PF07052.6 KXX79588.1 - 1.8e-18 66.8 2.1 1.8e-18 66.8 1.4 2.8 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DMAP_binding PF06464.6 KXX79588.1 - 0.032 14.8 0.3 0.032 14.8 0.2 3.1 3 0 0 3 3 3 0 DMAP1-binding Domain SKG6 PF08693.5 KXX79589.1 - 0.0038 16.5 1.7 0.008 15.4 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KXX79589.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 KXX79589.1 - 0.031 12.5 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lamp PF01299.12 KXX79589.1 - 4.2 6.4 5.8 2 7.4 0.3 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) WD40 PF00400.27 KXX79590.1 - 1.3e-25 88.2 11.3 2.8e-07 30.1 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KXX79590.1 - 0.00018 19.7 0.9 0.0014 16.9 0.4 2.3 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX79590.1 - 0.00059 18.7 0.2 1 8.0 0.0 3.3 1 1 3 4 4 4 2 Nup133 N terminal like Cyclin_N PF00134.18 KXX79590.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L6 PF00347.18 KXX79591.1 - 6.5e-25 87.4 7.6 4.4e-12 46.3 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 TMEM51 PF15345.1 KXX79592.1 - 0.0098 15.6 0.6 0.14 11.8 0.0 2.1 2 0 0 2 2 2 2 Transmembrane protein 51 DUF726 PF05277.7 KXX79593.1 - 5.2e-127 423.4 1.6 7.2e-127 423.0 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 KXX79593.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Dicty_REP PF05086.7 KXX79594.1 - 3.5 5.2 5.0 5.3 4.6 3.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sld5 PF05916.6 KXX79595.1 - 3.3e-13 49.8 0.0 5.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 KXX79595.1 - 0.079 12.5 0.1 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) Sulfate_transp PF00916.15 KXX79596.1 - 1.8e-32 112.5 0.4 1.8e-32 112.5 0.3 1.8 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KXX79596.1 - 3.9e-11 42.5 0.0 9.2e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KXX79596.1 - 3e-08 33.0 0.0 5.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain CitMHS PF03600.11 KXX79596.1 - 0.26 9.8 18.1 0.45 9.0 3.3 2.4 2 0 0 2 2 2 0 Citrate transporter V-ATPase_H_N PF03224.9 KXX79597.1 - 8.8e-77 258.2 0.0 1.2e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KXX79597.1 - 3.1e-39 133.5 0.0 1e-38 131.9 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H Med4 PF10018.4 KXX79597.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Fcf1 PF04900.7 KXX79598.1 - 2e-22 79.1 0.0 3.7e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.9 KXX79598.1 - 0.17 9.8 3.6 0.24 9.3 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KXX79598.1 - 4.1 6.9 17.9 8.5 5.9 12.4 1.5 1 1 0 1 1 1 0 YL1 nuclear protein SpoIIE PF07228.7 KXX79599.1 - 0.002 17.8 0.0 0.0074 16.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KXX79599.1 - 0.0063 15.9 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PH PF00169.24 KXX79600.1 - 1.9e-05 24.8 0.1 0.0002 21.4 0.0 2.5 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 KXX79600.1 - 0.001 19.2 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.20 KXX79601.1 - 1e-66 224.7 0.0 1.5e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79601.1 - 6.2e-30 104.1 0.0 1.4e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KXX79601.1 - 2.7e-10 40.2 0.0 2e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 FHA domain APH PF01636.18 KXX79601.1 - 0.0022 17.7 0.0 1.4 8.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KXX79601.1 - 0.0087 15.0 0.0 0.028 13.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX79601.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family STT3 PF02516.9 KXX79603.1 - 5.5e-132 441.1 38.2 2.5e-127 425.8 24.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 KXX79603.1 - 6.5e-05 22.4 14.7 6.5e-05 22.4 10.2 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytomega_TRL10 PF06084.6 KXX79603.1 - 1.1 9.0 2.1 1 9.1 0.1 1.9 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Ribosomal_L29 PF00831.18 KXX79604.1 - 1.6e-17 62.8 1.4 1.6e-17 62.8 1.0 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KXX79604.1 - 0.027 14.7 1.8 0.033 14.4 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Snapin_Pallidin PF14712.1 KXX79604.1 - 1.7 8.9 6.7 0.17 12.2 1.0 1.8 1 1 1 2 2 2 0 Snapin/Pallidin FlxA PF14282.1 KXX79604.1 - 4.6 7.2 7.5 0.37 10.7 2.1 1.5 2 0 0 2 2 2 0 FlxA-like protein AAA_2 PF07724.9 KXX79605.1 - 2.1e-44 151.4 0.0 2.9e-43 147.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KXX79605.1 - 1.1e-24 86.1 0.2 4.2e-24 84.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KXX79605.1 - 1.5e-19 70.5 0.0 2.1e-10 40.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX79605.1 - 1.8e-11 43.9 0.1 9.2e-09 35.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX79605.1 - 6.5e-09 36.0 14.3 0.0068 16.4 0.1 5.2 3 3 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 KXX79605.1 - 8.2e-09 35.7 1.0 0.0029 17.7 0.0 3.7 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KXX79605.1 - 1.8e-06 27.5 0.5 0.00044 19.7 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KXX79605.1 - 2.5e-06 27.4 0.0 0.076 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KXX79605.1 - 1.3e-05 25.0 9.5 0.23 11.1 0.0 4.7 3 2 1 4 4 4 2 Archaeal ATPase NACHT PF05729.7 KXX79605.1 - 2.9e-05 23.8 0.2 0.21 11.2 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 KXX79605.1 - 9.9e-05 23.1 3.7 0.022 15.5 0.1 3.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KXX79605.1 - 0.00044 19.6 0.0 0.44 9.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 KXX79605.1 - 0.00059 20.1 0.6 0.26 11.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 KXX79605.1 - 0.0011 18.2 0.1 0.93 8.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KXX79605.1 - 0.0011 19.2 7.8 0.15 12.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain MobB PF03205.9 KXX79605.1 - 0.0013 18.4 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KXX79605.1 - 0.0029 17.7 0.0 0.95 9.6 0.0 2.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 KXX79605.1 - 0.0044 16.9 1.3 5.6 6.9 0.0 4.0 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KXX79605.1 - 0.0056 16.5 0.3 5.6 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain ERM PF00769.14 KXX79605.1 - 0.0064 16.0 11.1 0.012 15.1 7.7 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_19 PF13245.1 KXX79605.1 - 0.0082 15.8 0.0 0.89 9.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 KXX79605.1 - 0.0093 15.4 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 KXX79605.1 - 0.018 14.9 1.2 5.5 6.7 0.0 3.6 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 KXX79605.1 - 0.022 13.9 0.2 2.3 7.3 0.0 3.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KXX79605.1 - 0.026 13.9 0.1 0.68 9.3 0.0 3.2 2 2 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KXX79605.1 - 0.027 13.8 1.3 12 5.2 0.1 3.0 2 2 1 3 3 3 0 AAA domain V_ATPase_I PF01496.14 KXX79605.1 - 0.044 11.6 4.5 0.064 11.1 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF815 PF05673.8 KXX79605.1 - 0.05 12.5 0.6 1.5 7.6 0.2 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KXX79605.1 - 0.062 12.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KXX79605.1 - 0.064 13.7 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KXX79605.1 - 0.073 12.6 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 KXX79605.1 - 0.11 11.7 3.0 0.81 8.9 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain APG6 PF04111.7 KXX79605.1 - 0.12 11.3 6.1 0.2 10.7 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4058 PF13267.1 KXX79605.1 - 0.14 11.2 1.6 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4058) ATP_bind_1 PF03029.12 KXX79605.1 - 0.15 11.5 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GBP_C PF02841.9 KXX79605.1 - 0.16 11.1 7.7 0.27 10.3 5.4 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Seryl_tRNA_N PF02403.17 KXX79605.1 - 0.21 11.5 13.9 0.29 11.1 8.1 2.5 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 KXX79605.1 - 0.25 11.2 12.9 0.49 10.2 9.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding OEP PF02321.13 KXX79605.1 - 0.32 10.5 11.2 0.78 9.3 7.8 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Mnd1 PF03962.10 KXX79605.1 - 0.44 10.1 12.8 0.83 9.2 8.9 1.4 1 0 0 1 1 1 0 Mnd1 family GrpE PF01025.14 KXX79605.1 - 1 8.8 9.0 2.7 7.4 6.3 1.7 1 0 0 1 1 1 0 GrpE Atg14 PF10186.4 KXX79605.1 - 2.3 7.0 8.5 4.5 6.1 5.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KXX79605.1 - 3 7.3 19.1 0.065 12.8 8.2 1.9 3 0 0 3 3 1 0 IncA protein TBPIP PF07106.8 KXX79605.1 - 5.9 6.4 10.7 16 5.0 7.4 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Arf PF00025.16 KXX79606.1 - 2.1e-78 261.5 0.2 2.5e-78 261.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KXX79606.1 - 1.9e-13 50.0 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KXX79606.1 - 6.4e-13 48.4 0.0 7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KXX79606.1 - 1.5e-12 46.9 1.1 5e-09 35.3 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KXX79606.1 - 3.3e-11 42.7 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KXX79606.1 - 1.5e-08 35.1 0.0 2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KXX79606.1 - 9.7e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KXX79606.1 - 0.0024 17.0 0.1 0.0056 15.7 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KXX79606.1 - 0.017 14.5 0.1 0.12 11.7 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KXX79606.1 - 0.042 13.7 0.1 0.084 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 KXX79607.1 - 5.6e-47 159.8 0.0 6.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 KXX79607.1 - 0.054 12.7 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Dioxygenase SpoU_methylase PF00588.14 KXX79607.1 - 0.083 12.7 0.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family DUF3405 PF11885.3 KXX79608.1 - 2.4e-205 682.4 1.1 3.1e-205 682.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) PBP1_TM PF14812.1 KXX79608.1 - 0.69 10.2 3.6 1.9 8.8 2.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_10 PF05176.9 KXX79610.1 - 5.4e-89 297.7 0.0 6.9e-89 297.4 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Rad51 PF08423.6 KXX79611.1 - 1.1e-137 457.0 0.0 1.4e-137 456.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KXX79611.1 - 3.9e-13 49.2 0.0 5.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KXX79611.1 - 2.4e-08 34.0 0.6 7.8e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KXX79611.1 - 4.2e-07 29.3 0.0 5.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KXX79611.1 - 3.6e-06 26.2 0.0 6.9e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 KXX79611.1 - 0.069 11.9 0.1 0.18 10.6 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 KXX79611.1 - 0.082 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Vps26 PF03643.10 KXX79613.1 - 7.8e-130 431.5 0.5 8.9e-130 431.3 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KXX79613.1 - 5.1e-05 23.1 0.1 0.59 9.9 0.0 3.5 2 1 1 3 3 3 3 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 KXX79613.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Nup160 PF11715.3 KXX79614.1 - 3.4e-157 523.9 0.0 4.7e-157 523.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Strep_SA_rep PF06696.6 KXX79614.1 - 0.07 12.8 0.8 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat EF-hand_1 PF00036.27 KXX79616.1 - 7.8e-27 90.5 7.7 1e-06 27.5 0.1 5.5 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KXX79616.1 - 5.1e-26 90.6 3.8 4.5e-10 39.5 0.6 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KXX79616.1 - 1e-21 74.8 8.0 0.00022 20.8 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KXX79616.1 - 1.1e-20 72.9 11.9 1.1e-08 34.5 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KXX79616.1 - 1.8e-17 61.7 9.6 0.00035 19.7 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KXX79616.1 - 0.081 12.8 0.3 1 9.3 0.0 2.7 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 KXX79616.1 - 0.12 12.0 0.1 17 5.2 0.0 3.0 2 1 1 3 3 3 0 EF hand DIOX_N PF14226.1 KXX79618.1 - 0.066 13.7 0.2 1 9.8 0.1 2.2 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ChaC PF04752.7 KXX79619.1 - 5.4e-53 179.5 0.0 6.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 KXX79620.1 - 1.1e-24 85.8 0.1 1.4e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX79620.1 - 2.3e-17 62.7 0.0 3.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79620.1 - 2.7e-11 43.1 0.0 4.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX79620.1 - 0.038 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif DUF1877 PF08974.5 KXX79620.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Ribosomal_L6e PF01159.14 KXX79621.1 - 1.6e-37 128.0 0.2 2.4e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e 2-oxoacid_dh PF00198.18 KXX79622.1 - 8.6e-74 247.6 0.0 1.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KXX79622.1 - 1.7e-17 62.8 0.2 3.3e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KXX79622.1 - 1.3e-11 43.9 0.0 3.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 KXX79622.1 - 0.13 12.5 0.2 0.74 10.0 0.0 2.2 2 1 0 2 2 2 0 Brain expressed X-linked like family V-SNARE_C PF12352.3 KXX79623.1 - 8e-12 45.0 0.2 8e-12 45.0 0.1 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SATase_N PF06426.9 KXX79623.1 - 0.028 14.6 2.1 0.24 11.6 0.3 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal STAT_alpha PF01017.15 KXX79623.1 - 0.052 13.2 1.6 0.39 10.4 0.5 2.3 2 1 0 2 2 2 0 STAT protein, all-alpha domain Adaptin_binding PF10199.4 KXX79623.1 - 0.071 13.3 0.9 0.11 12.8 0.6 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 APG6 PF04111.7 KXX79623.1 - 0.57 9.1 3.2 0.79 8.7 2.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 CorA PF01544.13 KXX79623.1 - 5.2 6.0 8.0 2.9 6.8 3.8 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ACPS PF01648.15 KXX79624.1 - 3.5e-07 30.0 0.0 9.7e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily K-cyclin_vir_C PF09080.5 KXX79624.1 - 0.073 13.2 0.1 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 K cyclin, C terminal CedA PF10729.4 KXX79624.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Cell division activator CedA Peptidase_A22B PF04258.8 KXX79625.1 - 2.3e-47 161.9 0.2 8e-47 160.1 0.2 1.8 1 1 0 1 1 1 1 Signal peptide peptidase PRA1 PF03208.14 KXX79625.1 - 5.5 6.3 7.6 7.8 5.8 0.0 3.0 3 0 0 3 3 3 0 PRA1 family protein SUR7 PF06687.7 KXX79626.1 - 1.3e-33 116.3 3.5 1.7e-33 115.9 2.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KXX79626.1 - 0.00019 21.1 13.0 0.00019 21.1 9.0 2.0 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KXX79626.1 - 0.0022 17.6 12.5 0.005 16.4 8.7 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein Clc-like PF07062.7 KXX79626.1 - 0.069 12.3 5.7 0.1 11.8 4.0 1.3 1 0 0 1 1 1 0 Clc-like Epiglycanin_C PF14654.1 KXX79626.1 - 0.085 12.8 1.8 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Ank_4 PF13637.1 KXX79627.1 - 4.1e-11 43.0 0.0 8.9e-06 26.0 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX79627.1 - 7.3e-11 42.2 0.1 7.3e-10 39.0 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX79627.1 - 5.6e-10 38.4 0.2 0.0037 17.3 0.0 4.0 4 1 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 KXX79627.1 - 8.1e-09 34.8 1.0 0.052 13.3 0.0 4.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KXX79627.1 - 2.3e-07 30.8 0.2 0.1 12.9 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) HSP70 PF00012.15 KXX79628.1 - 2.6e-11 42.1 0.3 1.1e-09 36.8 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KXX79628.1 - 0.0041 16.7 0.1 0.009 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KXX79628.1 - 0.029 12.9 0.1 0.15 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Med31 PF05669.7 KXX79629.1 - 7.1e-37 125.2 0.6 7.9e-37 125.1 0.4 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 KXX79630.1 - 3.7e-20 71.2 3.0 3.7e-20 71.2 2.0 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KXX79630.1 - 2.5e-08 33.4 0.1 2.5e-08 33.4 0.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 KXX79630.1 - 0.094 12.4 2.8 1.5 8.5 0.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 KXX79630.1 - 0.13 12.2 2.3 0.86 9.5 0.0 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.2 KXX79630.1 - 0.2 11.5 5.4 0.36 10.6 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 KXX79630.1 - 0.4 10.5 7.0 5.7 6.8 1.6 2.8 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 KXX79630.1 - 0.42 10.6 3.8 14 5.7 0.5 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain C1_3 PF07649.7 KXX79630.1 - 0.54 10.3 0.2 0.54 10.3 0.1 2.5 3 0 0 3 3 3 0 C1-like domain Rpr2 PF04032.11 KXX79630.1 - 5.9 6.8 5.8 55 3.7 4.0 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mem_trans PF03547.13 KXX79631.1 - 4.9e-51 173.2 0.0 9.5e-51 172.2 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 KXX79632.1 - 6.5e-47 159.8 0.0 1.2e-44 152.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX79632.1 - 3e-28 98.6 0.0 3.6e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX79632.1 - 0.00054 19.0 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KXX79632.1 - 0.0016 17.3 0.1 0.0025 16.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KXX79632.1 - 0.075 11.8 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KXX79632.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_26 PF02156.10 KXX79633.1 - 1.8e-92 310.1 3.9 2.2e-92 309.8 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DUF1888 PF08985.6 KXX79633.1 - 0.023 14.3 0.3 0.056 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1888) Glycoprotein PF03409.10 KXX79633.1 - 0.027 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Endotoxin_C PF03944.9 KXX79633.1 - 0.14 12.2 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 delta endotoxin Transp_cyt_pur PF02133.10 KXX79634.1 - 2e-09 36.5 42.3 2.5e-09 36.1 24.6 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin His_Phos_2 PF00328.17 KXX79635.1 - 3.1e-17 62.9 0.2 2.5e-15 56.6 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3377 PF11857.3 KXX79635.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Epimerase PF01370.16 KXX79636.1 - 1.4e-17 63.9 0.0 1.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX79636.1 - 3.4e-12 45.6 0.0 4.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX79636.1 - 2.3e-09 36.5 0.0 5.1e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KXX79636.1 - 5.9e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KXX79636.1 - 2.9e-08 33.9 0.0 5.2e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KXX79636.1 - 2.2e-06 27.4 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX79636.1 - 4.8e-06 25.6 0.0 1.1e-05 24.4 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KXX79636.1 - 1.5e-05 24.2 0.1 4.3e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Saccharopine dehydrogenase NmrA PF05368.8 KXX79636.1 - 0.0018 17.5 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 KXX79636.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KXX79636.1 - 0.033 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 KXX79636.1 - 0.035 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KXX79636.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TIR PF01582.15 KXX79636.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain FAD_binding_3 PF01494.14 KXX79637.1 - 2.3e-23 82.8 0.7 4.1e-11 42.5 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KXX79637.1 - 5.3e-05 22.2 0.1 0.00012 21.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX79637.1 - 0.00032 21.0 3.5 0.00048 20.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX79637.1 - 0.00041 20.3 3.1 0.00042 20.2 0.4 2.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX79637.1 - 0.0024 17.6 0.0 0.009 15.7 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX79637.1 - 0.037 14.1 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX79637.1 - 0.081 12.7 0.4 0.2 11.5 0.2 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KXX79637.1 - 0.087 11.6 0.1 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase F-box-like PF12937.2 KXX79638.1 - 0.00093 18.8 0.1 0.0022 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3786 PF12654.2 KXX79638.1 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3786) F-box PF00646.28 KXX79638.1 - 0.0054 16.3 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain AAA_33 PF13671.1 KXX79639.1 - 2.1e-13 50.3 0.2 2.9e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX79639.1 - 3.2e-09 37.6 0.0 5.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KXX79639.1 - 8.9e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 KXX79639.1 - 5.7e-08 33.1 0.1 1.3e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KXX79639.1 - 3.9e-05 23.6 0.3 0.00019 21.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KXX79639.1 - 0.00026 21.2 0.2 0.00066 19.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KXX79639.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KXX79639.1 - 0.0027 18.0 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KXX79639.1 - 0.0062 15.2 0.0 0.015 14.0 0.0 1.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 KXX79639.1 - 0.009 15.6 0.1 0.018 14.6 0.1 1.5 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KXX79639.1 - 0.01 15.8 0.6 0.028 14.3 0.4 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KXX79639.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Cytidylate_kin2 PF13189.1 KXX79639.1 - 0.018 14.9 0.1 0.042 13.7 0.1 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family ABC_tran PF00005.22 KXX79639.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.15 KXX79639.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase IPT PF01745.11 KXX79639.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_22 PF13401.1 KXX79639.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX79639.1 - 0.036 13.4 0.2 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX79639.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Tubulin PF00091.20 KXX79639.1 - 0.074 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Parvo_NS1 PF01057.12 KXX79639.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.6 KXX79639.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.9 1 1 0 1 1 1 0 tRNA ligase kinase domain PRK PF00485.13 KXX79639.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 KXX79639.1 - 0.16 11.6 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase RhoGAP PF00620.22 KXX79640.1 - 1.1e-10 41.3 0.0 1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain FAD_binding_7 PF03441.9 KXX79641.1 - 4.8e-58 196.5 0.0 6.9e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KXX79641.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase GMC_oxred_N PF00732.14 KXX79642.1 - 3.7e-59 200.3 0.0 2.1e-58 197.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79642.1 - 4.2e-36 124.3 0.0 6.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX79642.1 - 8.6e-06 24.8 3.3 0.0033 16.3 1.7 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX79642.1 - 1.8e-05 23.8 1.3 0.00014 20.8 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX79642.1 - 0.0002 20.4 0.8 0.00048 19.1 0.7 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX79642.1 - 0.0016 18.4 1.3 0.0046 16.9 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX79642.1 - 0.0051 16.9 1.0 0.54 10.2 1.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX79642.1 - 0.0094 15.0 0.1 0.027 13.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KXX79642.1 - 0.039 13.8 0.5 0.11 12.3 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX79642.1 - 0.13 11.9 1.4 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KXX79642.1 - 0.42 9.0 1.2 0.69 8.3 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyridox_oxidase PF01243.15 KXX79644.1 - 4.6e-12 45.7 0.0 8.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 KXX79644.1 - 0.0011 17.0 0.0 0.0014 16.7 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component CPSase_L_D2 PF02786.12 KXX79645.1 - 9.4e-74 247.2 0.0 1.4e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KXX79645.1 - 2.3e-35 120.7 0.0 4.7e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KXX79645.1 - 1.5e-33 115.2 0.0 3.1e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KXX79645.1 - 1.3e-18 67.3 0.0 2.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KXX79645.1 - 1.1e-15 57.0 0.4 2.6e-15 55.8 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KXX79645.1 - 4.8e-14 51.8 0.0 8.7e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX79645.1 - 1.2e-07 31.2 0.0 2.7e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KXX79645.1 - 1.6e-07 30.8 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KXX79645.1 - 4.9e-07 29.3 0.0 0.029 14.0 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 KXX79645.1 - 2.7e-05 23.6 0.1 0.021 14.1 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KXX79645.1 - 2.7e-05 24.0 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KXX79645.1 - 0.0035 17.6 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.6 KXX79645.1 - 0.02 14.3 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Nairovirus_M PF07948.6 KXX79645.1 - 0.062 11.4 0.0 0.09 10.8 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like 4HBT PF03061.17 KXX79646.1 - 6.8e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Hamartin PF04388.7 KXX79646.1 - 0.11 11.1 1.8 0.15 10.6 1.3 1.1 1 0 0 1 1 1 0 Hamartin protein TP_methylase PF00590.15 KXX79647.1 - 4e-44 150.8 0.0 8.8e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 KXX79647.1 - 6.1e-08 31.8 0.1 3.8e-06 26.1 0.0 2.7 3 0 0 3 3 3 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KXX79647.1 - 0.00012 20.9 0.0 0.00022 20.0 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 KXX79647.1 - 0.0038 17.4 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding LVIVD PF08309.6 KXX79648.1 - 2.2e-12 45.7 2.9 0.015 14.3 0.0 5.3 5 0 0 5 5 5 5 LVIVD repeat Glyco_hydro_3 PF00933.16 KXX79649.1 - 1.7e-87 293.2 0.0 2.6e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX79649.1 - 8.8e-55 185.6 0.1 2.7e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX79649.1 - 2.2e-26 91.5 0.0 4.3e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Podoplanin PF05808.6 KXX79651.1 - 0.0093 15.5 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 KXX79651.1 - 0.029 13.0 0.3 0.041 12.5 0.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1183 PF06682.7 KXX79651.1 - 0.055 13.0 1.0 0.064 12.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Rax2 PF12768.2 KXX79651.1 - 0.1 11.7 0.3 0.2 10.8 0.1 1.5 1 1 1 2 2 2 0 Cortical protein marker for cell polarity MtrF PF09472.5 KXX79651.1 - 0.11 11.8 0.6 0.18 11.0 0.4 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glyco_hydro_3 PF00933.16 KXX79653.1 - 2.4e-59 200.7 0.0 3.5e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX79653.1 - 1.5e-43 148.9 0.0 2.2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX79653.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_5 PF00266.14 KXX79654.1 - 2.1e-20 72.7 0.0 9.2e-20 70.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M54 PF07998.6 KXX79655.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M54 Reprolysin_2 PF13574.1 KXX79655.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Arginase PF00491.16 KXX79656.1 - 1.9e-18 66.7 0.0 4.1e-18 65.6 0.0 1.6 1 1 0 1 1 1 1 Arginase family Cas_Csy2 PF09614.5 KXX79656.1 - 0.049 12.8 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Hexokinase_1 PF00349.16 KXX79657.1 - 2.5e-64 216.3 0.0 5.4e-64 215.3 0.0 1.5 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KXX79657.1 - 6.8e-64 215.3 0.0 1.2e-63 214.5 0.0 1.4 1 1 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 KXX79659.1 - 1.4e-34 119.4 17.2 1.4e-34 119.4 11.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BTB PF00651.26 KXX79660.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain C1_2 PF03107.11 KXX79661.1 - 0.087 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 C1 domain FAD_binding_4 PF01565.18 KXX79662.1 - 4e-18 65.2 1.9 5.1e-18 64.8 0.6 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 KXX79662.1 - 6e-12 45.2 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TAT_signal PF10518.4 KXX79662.1 - 5.2 7.3 8.1 15 5.8 0.6 3.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence F-box-like PF12937.2 KXX79663.1 - 3e-05 23.6 0.3 6.3e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX79663.1 - 0.035 13.7 1.3 7.2 6.3 0.1 2.8 2 0 0 2 2 2 0 F-box domain PIG-U PF06728.8 KXX79664.1 - 8.5e-09 34.7 0.1 1.2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 KXX79664.1 - 2e-08 34.1 0.0 4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 KXX79664.1 - 0.02 14.4 12.9 0.034 13.6 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) SQS_PSY PF00494.14 KXX79665.1 - 9.5e-40 136.5 0.0 3.8e-39 134.5 0.0 1.8 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF2244 PF10003.4 KXX79665.1 - 0.2 10.9 3.1 8.5 5.7 2.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Peptidase_S8 PF00082.17 KXX79666.1 - 1.1e-51 175.6 11.4 1.5e-51 175.2 7.9 1.1 1 0 0 1 1 1 1 Subtilase family DnaJ-X PF14308.1 KXX79667.1 - 2.9e-71 238.9 1.5 2.9e-71 238.9 1.1 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KXX79667.1 - 4.4e-27 93.6 1.3 1e-26 92.4 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain DUF2680 PF10925.3 KXX79667.1 - 0.12 12.2 2.4 0.16 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) RmlD_sub_bind PF04321.12 KXX79668.1 - 9e-15 54.3 0.0 1.6e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KXX79668.1 - 1.2e-13 51.1 0.0 2.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX79668.1 - 0.00028 19.8 0.0 0.00065 18.6 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KXX79668.1 - 0.0059 16.5 0.1 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Macro PF01661.16 KXX79668.1 - 0.09 12.6 0.2 0.3 10.9 0.0 2.0 3 0 0 3 3 3 0 Macro domain 3Beta_HSD PF01073.14 KXX79668.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.23 KXX79669.1 - 1.6e-73 247.5 0.0 1.9e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX79669.1 - 6.1e-10 39.9 0.2 1.4e-09 38.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3501 PF12007.3 KXX79669.1 - 0.21 11.2 0.1 0.33 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) AhpC-TSA PF00578.16 KXX79670.1 - 8.6e-31 106.1 0.0 1.2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KXX79670.1 - 5.1e-12 45.2 0.1 1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KXX79670.1 - 3.4e-11 42.9 0.0 4.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_3 PF13415.1 KXX79671.1 - 1.6e-20 72.6 1.9 1.3e-10 41.1 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KXX79671.1 - 1.8e-19 69.2 2.0 2.1e-09 36.9 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX79671.1 - 3e-12 46.2 7.0 6.9e-06 25.8 0.1 4.6 3 2 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KXX79671.1 - 5.3e-12 45.0 0.2 0.00056 19.4 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 KXX79671.1 - 7e-11 41.8 2.8 0.00074 19.5 0.3 4.9 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KXX79671.1 - 1.4e-07 30.9 0.2 0.0058 16.3 0.0 4.4 3 1 0 3 3 3 1 Kelch motif BTB PF00651.26 KXX79671.1 - 0.0041 17.0 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain AMP-binding PF00501.23 KXX79672.1 - 8.9e-92 307.6 0.1 1.1e-91 307.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX79672.1 - 1e-12 48.8 0.0 2.7e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 KXX79673.1 - 4.5e-16 59.0 0.1 7.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KXX79673.1 - 0.029 14.5 0.1 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Herpes_heli_pri PF05774.6 KXX79673.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component Pyr_redox PF00070.22 KXX79674.1 - 2.6e-14 53.3 0.1 3e-11 43.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX79674.1 - 1.6e-10 41.1 0.0 7.2e-09 35.8 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX79674.1 - 5.3e-10 39.7 0.0 0.0001 22.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX79674.1 - 4.3e-06 26.0 1.1 0.033 13.2 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 KXX79674.1 - 3.1e-05 23.0 0.2 8.2e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KXX79674.1 - 0.002 17.0 0.2 0.0047 15.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KXX79674.1 - 0.0033 16.3 2.3 0.027 13.3 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX79674.1 - 0.0082 16.1 0.1 3.1 7.8 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX79674.1 - 0.02 14.6 1.0 4.7 6.9 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KXX79674.1 - 0.026 13.1 0.8 0.57 8.7 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 KXX79674.1 - 0.12 11.1 0.1 6.1 5.5 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KXX79674.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KXX79674.1 - 0.24 9.8 0.7 1.3 7.4 0.1 2.2 3 0 0 3 3 3 0 HI0933-like protein Sugar_tr PF00083.19 KXX79675.1 - 3.6e-92 309.3 18.9 4.4e-92 309.0 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX79675.1 - 8.6e-24 83.8 33.5 5.3e-23 81.3 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 KXX79675.1 - 0.039 14.0 1.2 0.65 10.1 0.6 2.7 2 0 0 2 2 2 0 Phage holin family 2 adh_short PF00106.20 KXX79676.1 - 5.8e-30 104.4 0.0 7.8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX79676.1 - 3.4e-10 39.8 0.0 5.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX79676.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 KXX79677.1 - 2.1e-15 56.2 0.0 4.2e-10 38.7 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 PIG-S PF10510.4 KXX79678.1 - 6.6e-147 490.2 0.0 7.8e-147 490.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein WD40 PF00400.27 KXX79680.1 - 4.4e-20 70.7 9.5 8.8e-08 31.7 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Translin PF01997.11 KXX79681.1 - 1.4e-64 217.3 0.0 1.7e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Translin family EF1_GNE PF00736.14 KXX79682.1 - 6e-32 109.2 1.8 1e-31 108.4 1.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KXX79682.1 - 6.3e-14 51.8 9.2 6.3e-14 51.8 6.4 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KXX79682.1 - 0.0075 16.7 0.2 0.02 15.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX79682.1 - 0.018 14.9 1.9 0.029 14.3 0.0 2.2 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 KXX79682.1 - 4.5 6.9 7.6 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF1996 PF09362.5 KXX79683.1 - 5.2e-88 294.6 0.6 6.2e-88 294.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DAN PF03045.10 KXX79683.1 - 2.9 7.3 7.7 1.4 8.3 0.2 3.0 3 1 1 4 4 4 0 DAN domain GMC_oxred_N PF00732.14 KXX79684.1 - 1.6e-60 204.7 0.0 2.1e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79684.1 - 1.4e-33 116.1 0.0 2.3e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX79684.1 - 2e-06 26.9 0.4 0.00071 18.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KXX79684.1 - 9.9e-06 25.4 0.2 2.5e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX79684.1 - 1.1e-05 24.5 1.8 0.0031 16.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX79684.1 - 0.0001 22.4 0.7 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX79684.1 - 0.00019 21.3 1.3 0.0026 17.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX79684.1 - 0.00039 19.0 0.5 0.0045 15.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 KXX79684.1 - 0.01 14.7 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KXX79684.1 - 0.014 14.5 0.1 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KXX79684.1 - 0.03 13.2 0.9 0.65 8.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KXX79684.1 - 0.032 13.2 0.1 0.073 12.1 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KXX79684.1 - 0.034 12.7 0.1 0.051 12.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX79684.1 - 0.092 12.5 0.6 0.68 9.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amidohydro_2 PF04909.9 KXX79685.1 - 3.1e-38 131.9 1.5 4.1e-38 131.4 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase HEV_ORF1 PF02444.11 KXX79686.1 - 0.005 17.0 0.7 0.013 15.6 0.5 1.7 1 0 0 1 1 1 1 Hepatitis E virus ORF-2 (Putative capsid protein) Complex1_LYR_1 PF13232.1 KXX79687.1 - 6.2e-17 61.5 0.3 7.6e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KXX79687.1 - 1.2e-15 57.0 0.1 1.5e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KXX79687.1 - 0.0026 18.2 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L36 PF00444.13 KXX79688.1 - 3.3e-21 74.9 11.4 5e-21 74.3 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 PLAC8 PF04749.12 KXX79689.1 - 5.5e-14 52.6 1.9 6.7e-14 52.3 1.3 1.1 1 0 0 1 1 1 1 PLAC8 family Acetyltransf_1 PF00583.19 KXX79690.1 - 4.8e-11 42.5 0.0 7.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX79690.1 - 7.4e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX79690.1 - 7.1e-05 22.4 0.0 0.00046 19.8 0.0 2.1 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.1 KXX79690.1 - 0.0029 17.7 0.0 0.0038 17.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX79690.1 - 0.0046 17.0 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KXX79690.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4239 PF14023.1 KXX79691.1 - 0.23 10.8 2.7 0.45 9.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CTP_transf_2 PF01467.21 KXX79692.1 - 0.0055 16.7 0.5 0.11 12.4 0.2 2.7 2 1 0 2 2 2 1 Cytidylyltransferase WD40 PF00400.27 KXX79694.1 - 0.00037 20.2 0.7 0.0015 18.3 0.1 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Cyclin PF08613.6 KXX79695.1 - 5.7e-39 133.8 2.4 3.9e-23 82.5 0.2 2.6 2 0 0 2 2 2 2 Cyclin DUF2457 PF10446.4 KXX79695.1 - 0.0052 15.5 12.7 0.0052 15.5 8.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 KXX79695.1 - 0.54 8.1 12.5 0.89 7.4 8.7 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 KXX79695.1 - 6.8 5.8 9.9 12 5.0 6.9 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KXX79695.1 - 9.3 5.7 9.9 11 5.4 6.3 1.6 2 0 0 2 2 2 0 Nucleoplasmin SET PF00856.23 KXX79696.1 - 2e-09 37.9 0.0 7e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KXX79696.1 - 0.00018 21.0 0.1 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 TPR repeat PSCyt2 PF07583.6 KXX79696.1 - 0.0051 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) Sugar_tr PF00083.19 KXX79697.1 - 9.3e-90 301.3 24.8 1.2e-89 301.0 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX79697.1 - 3.6e-14 52.2 44.2 3.3e-08 32.6 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3445 PF11927.3 KXX79698.1 - 5e-63 212.7 0.0 6.1e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Pyr_redox PF00070.22 KXX79699.1 - 2.3e-18 66.3 0.1 1.7e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX79699.1 - 6.5e-15 55.5 0.0 1.7e-05 24.7 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX79699.1 - 2.7e-11 42.9 0.1 0.00047 19.1 0.1 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX79699.1 - 3.9e-09 36.8 0.0 0.00021 21.4 0.0 3.6 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX79699.1 - 5.6e-06 25.5 0.0 1.2e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KXX79699.1 - 7.9e-06 24.7 0.0 0.057 12.0 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 KXX79699.1 - 0.00016 21.4 0.3 7 6.4 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KXX79699.1 - 0.0002 21.2 0.1 0.55 10.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KXX79699.1 - 0.00044 20.4 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX79699.1 - 0.00088 18.2 0.0 0.042 12.7 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.11 KXX79699.1 - 0.028 13.8 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KXX79699.1 - 0.035 14.1 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Abhydrolase_3 PF07859.8 KXX79701.1 - 3.1e-14 53.0 0.1 4.5e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX79701.1 - 0.059 13.2 0.8 0.14 12.0 0.6 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79702.1 - 2.3e-05 24.1 0.0 0.00022 21.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX79702.1 - 0.00022 21.1 6.3 0.0015 18.4 4.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX79702.1 - 0.007 15.6 0.0 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KXX79702.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3336 PF11815.3 KXX79703.1 - 7.6e-42 142.2 0.9 1.4e-41 141.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KXX79703.1 - 2.7e-23 82.9 0.1 5e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TMEM154 PF15102.1 KXX79704.1 - 0.076 12.7 0.8 0.22 11.2 0.5 1.7 1 1 0 1 1 1 0 TMEM154 protein family Glyco_hydro_61 PF03443.9 KXX79706.1 - 6.3e-70 235.3 0.1 7.3e-70 235.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Transport_MerF PF11431.3 KXX79706.1 - 0.062 12.9 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein MerF fn3 PF00041.16 KXX79706.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain DHO_dh PF01180.16 KXX79707.1 - 8e-68 228.5 0.0 3.2e-67 226.5 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KXX79707.1 - 0.00053 19.3 1.3 0.27 10.4 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 KXX79707.1 - 0.015 14.1 1.1 0.14 11.0 0.5 2.3 2 1 0 2 2 2 0 FMN-dependent dehydrogenase GCR1_C PF12550.3 KXX79709.1 - 1.5e-22 79.2 2.1 2e-22 78.8 1.5 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes F5_F8_type_C PF00754.20 KXX79709.1 - 5.9e-05 22.9 0.2 7.4e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 F5/8 type C domain TMEM240 PF15207.1 KXX79709.1 - 0.043 13.4 3.4 0.11 12.0 1.2 2.0 2 0 0 2 2 2 0 TMEM240 family ketoacyl-synt PF00109.21 KXX79710.1 - 5e-67 226.0 0.1 1.7e-66 224.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX79710.1 - 9.1e-61 205.9 0.5 1.9e-60 204.8 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 KXX79710.1 - 7.5e-56 188.6 0.2 2.2e-55 187.1 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX79710.1 - 3.3e-45 154.0 0.2 1.9e-44 151.5 0.1 2.5 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX79710.1 - 7.6e-39 132.2 0.0 2.4e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KXX79710.1 - 8.2e-39 133.5 3.3 1.8e-38 132.3 2.3 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 KXX79710.1 - 2.2e-16 59.6 0.1 9.1e-16 57.5 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KXX79710.1 - 8.9e-16 58.1 0.0 2.9e-15 56.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KXX79710.1 - 3.6e-12 47.2 0.0 1.8e-11 45.0 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KXX79710.1 - 1.3e-11 44.4 0.0 3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX79710.1 - 7.6e-10 38.9 0.0 2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KXX79710.1 - 2.4e-08 34.5 0.0 1e-07 32.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79710.1 - 2.3e-06 28.0 0.0 7e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79710.1 - 6.3e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 KXX79710.1 - 0.00088 18.8 0.6 0.0022 17.5 0.4 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_26 PF13659.1 KXX79710.1 - 0.023 14.7 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 KXX79710.1 - 0.049 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Corona_S1 PF01600.11 KXX79710.1 - 0.68 8.1 0.0 1.1 7.4 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein p450 PF00067.17 KXX79712.1 - 1.8e-55 188.3 0.0 2.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 KXX79713.1 - 5.4e-34 117.4 0.0 6.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX79713.1 - 0.00031 20.7 0.0 0.14 12.0 0.0 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX79713.1 - 0.14 11.6 2.6 0.44 9.9 0.4 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 KXX79714.1 - 3e-26 91.9 27.2 3e-26 91.9 18.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX79714.1 - 4e-12 45.1 7.3 3.7e-10 38.6 3.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KXX79714.1 - 0.00079 17.6 3.0 0.00079 17.6 2.0 2.5 2 1 1 3 3 3 2 Transmembrane secretion effector DUF106 PF01956.11 KXX79714.1 - 0.042 13.3 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 Pam17 PF08566.5 KXX79714.1 - 0.23 11.1 2.1 0.65 9.6 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 adh_short PF00106.20 KXX79715.1 - 1.9e-26 93.0 1.7 2.8e-26 92.4 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX79715.1 - 8e-18 65.0 0.0 9.7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX79715.1 - 1.6e-07 31.1 0.9 2.5e-07 30.5 0.4 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX79715.1 - 1.1e-05 25.5 0.4 5.8e-05 23.1 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KXX79715.1 - 0.0029 17.1 1.1 0.0046 16.5 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KXX79715.1 - 0.0029 17.0 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Toluene_X PF03349.11 KXX79715.1 - 0.012 14.0 0.1 0.017 13.5 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) NmrA PF05368.8 KXX79715.1 - 0.035 13.3 0.2 0.11 11.7 0.1 1.8 1 1 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 KXX79715.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KXX79715.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 KXX79715.1 - 0.075 11.9 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain zf-RING_2 PF13639.1 KXX79716.1 - 1.7e-09 37.3 7.5 3.9e-09 36.1 5.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KXX79716.1 - 5.5e-09 36.0 4.2 1.3e-08 34.8 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KXX79716.1 - 2.3e-06 27.4 8.7 9.2e-06 25.5 6.0 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 KXX79716.1 - 9.3e-06 25.2 8.7 1.8e-05 24.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX79716.1 - 1.8e-05 24.5 3.1 1.8e-05 24.5 2.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KXX79716.1 - 0.00027 20.5 4.9 0.00046 19.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX79716.1 - 0.00061 19.7 8.6 0.0012 18.8 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KXX79716.1 - 0.0025 17.7 7.6 0.0055 16.7 5.3 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.6 KXX79716.1 - 0.067 13.1 8.0 0.13 12.3 5.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 KXX79716.1 - 0.14 11.9 8.6 0.24 11.1 5.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 KXX79716.1 - 0.14 11.7 4.2 0.29 10.6 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.17 KXX79716.1 - 0.19 11.4 4.5 0.41 10.4 3.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_RING PF05883.6 KXX79716.1 - 0.43 10.4 1.6 0.99 9.2 1.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 KXX79716.1 - 0.5 10.1 3.7 1.2 8.8 2.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KXX79716.1 - 8.3 6.1 7.3 14 5.4 5.0 1.4 1 0 0 1 1 1 0 PHD-finger COesterase PF00135.23 KXX79717.1 - 1.9e-81 274.4 0.0 2.9e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.14 KXX79717.1 - 1.5e-15 57.1 0.0 4.2e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Abhydrolase_3 PF07859.8 KXX79717.1 - 8.2e-11 41.8 0.0 2.3e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DAO PF01266.19 KXX79717.1 - 0.00062 18.7 0.4 0.097 11.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KXX79717.1 - 0.00089 18.4 0.0 0.066 12.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Peptidase_S9 PF00326.16 KXX79717.1 - 0.005 16.0 0.1 0.0095 15.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family NAD_binding_8 PF13450.1 KXX79717.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mac PF12464.3 KXX79718.1 - 2.8e-19 68.8 0.0 6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KXX79718.1 - 2.4e-15 55.2 3.8 1.5e-11 43.2 3.1 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KXX79718.1 - 2.4e-12 46.1 3.9 2.4e-09 36.5 2.0 2.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase UDPGT PF00201.13 KXX79719.1 - 2.8e-20 72.3 0.0 5.9e-20 71.2 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 KXX79719.1 - 0.0014 17.8 0.0 0.0044 16.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KXX79719.1 - 0.0016 18.1 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SKG6 PF08693.5 KXX79721.1 - 2.6e-05 23.4 1.0 4.7e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Metallophos_2 PF12850.2 KXX79722.1 - 1.6e-05 24.7 0.0 3.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX79722.1 - 1.7e-05 24.3 0.6 0.00012 21.5 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SH3_3 PF08239.6 KXX79723.1 - 1.3e-06 28.4 0.2 3.4e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_5 PF05382.8 KXX79723.1 - 0.00022 20.8 0.5 0.00022 20.8 0.3 2.5 2 1 0 2 2 2 1 Bacteriophage peptidoglycan hydrolase NLPC_P60 PF00877.14 KXX79723.1 - 0.0031 17.2 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family SH3_4 PF06347.8 KXX79723.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain S-methyl_trans PF02574.11 KXX79723.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase MFS_1 PF07690.11 KXX79724.1 - 2.2e-36 125.3 46.7 1.4e-28 99.6 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX79724.1 - 1.4e-12 46.9 14.3 1.4e-12 46.9 9.9 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Lipase_3 PF01764.20 KXX79725.1 - 2.9e-09 36.6 0.0 3.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KXX79725.1 - 0.00069 19.2 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KXX79725.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KXX79725.1 - 0.12 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FAD_binding_3 PF01494.14 KXX79728.1 - 9.5e-11 41.3 0.8 1.9e-06 27.1 0.8 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX79728.1 - 8.5e-07 28.1 1.0 1.3e-05 24.3 0.3 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX79728.1 - 2.2e-06 27.6 0.1 4.5e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX79728.1 - 0.0019 18.0 0.0 0.0078 16.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX79728.1 - 0.0048 16.6 0.2 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KXX79728.1 - 0.012 16.0 0.1 0.032 14.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KXX79728.1 - 0.012 15.2 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KXX79728.1 - 0.018 14.4 0.2 0.048 13.1 0.1 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KXX79728.1 - 0.034 12.9 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KXX79728.1 - 0.039 12.8 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 KXX79728.1 - 0.19 11.7 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain p450 PF00067.17 KXX79730.1 - 2.9e-48 164.5 0.0 4.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1007 PF06226.8 KXX79731.1 - 0.092 12.4 0.1 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) ketoacyl-synt PF00109.21 KXX79732.1 - 2.8e-80 269.4 0.0 5.1e-80 268.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX79732.1 - 6.4e-62 208.4 0.4 1.7e-61 207.0 0.3 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KXX79732.1 - 1.8e-55 188.5 0.1 5.1e-55 187.0 0.1 1.8 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX79732.1 - 4.8e-54 183.5 0.3 8.4e-54 182.7 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX79732.1 - 1.6e-48 164.7 4.5 3.4e-48 163.6 0.6 3.1 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX79732.1 - 5.8e-41 139.0 0.1 1.6e-40 137.6 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX79732.1 - 4.1e-21 74.8 0.1 4e-20 71.6 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KXX79732.1 - 8.7e-21 74.2 0.0 2.4e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KXX79732.1 - 2.2e-15 57.6 0.0 1.5e-14 54.9 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KXX79732.1 - 2.2e-13 50.2 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79732.1 - 2.1e-09 37.7 0.0 8.9e-09 35.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79732.1 - 1.1e-08 34.8 0.0 3.1e-08 33.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KXX79732.1 - 2.6e-08 33.5 2.2 3.4e-08 33.1 0.7 1.8 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 KXX79732.1 - 9e-07 29.1 0.0 0.0002 21.6 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79732.1 - 1.7e-06 28.5 0.0 5.9e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX79732.1 - 1.9e-05 23.9 0.0 4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KXX79732.1 - 3.4e-05 22.9 0.0 6.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KXX79732.1 - 0.00012 22.2 0.1 0.00034 20.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KXX79732.1 - 0.0041 16.5 0.1 0.093 12.1 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ACP_syn_III_C PF08541.5 KXX79732.1 - 0.027 14.4 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CoA_trans PF01144.18 KXX79732.1 - 0.08 12.1 0.0 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase F420_oxidored PF03807.12 KXX79732.1 - 0.099 13.0 0.3 0.66 10.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Palm_thioest PF02089.10 KXX79733.1 - 3.3e-54 183.7 0.0 4e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 KXX79733.1 - 0.00063 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KXX79733.1 - 0.0091 15.1 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) EF-hand_like PF09279.6 KXX79733.1 - 0.011 15.7 0.2 0.019 14.9 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like BCNT PF07572.7 KXX79733.1 - 0.083 12.8 0.4 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Bucentaur or craniofacial development Ribosomal_L1 PF00687.16 KXX79734.1 - 5.9e-60 202.3 0.1 1.1e-59 201.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3227 PF11537.3 KXX79734.1 - 0.02 14.9 0.1 5 7.3 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3227) p450 PF00067.17 KXX79735.1 - 8.4e-63 212.4 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OrfB_Zn_ribbon PF07282.6 KXX79737.1 - 0.00048 19.7 9.0 0.3 10.7 0.1 3.9 3 1 1 4 4 4 2 Putative transposase DNA-binding domain DZR PF12773.2 KXX79737.1 - 0.0035 17.1 11.3 0.36 10.6 3.3 2.9 1 1 1 2 2 2 2 Double zinc ribbon DUF1561 PF07598.6 KXX79737.1 - 0.05 11.5 0.6 0.066 11.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) PADR1 PF08063.7 KXX79737.1 - 0.68 9.3 7.6 5.4 6.5 0.3 3.2 3 0 0 3 3 3 0 PADR1 (NUC008) domain DNA_RNApol_7kD PF03604.8 KXX79737.1 - 1.1 8.7 0.1 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 KXX79737.1 - 3.6 6.9 8.5 8.2 5.8 0.0 3.9 2 1 1 4 4 4 0 TFIIB zinc-binding ResIII PF04851.10 KXX79739.1 - 1e-20 74.3 0.0 2.8e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KXX79739.1 - 2.2e-20 72.3 0.0 5.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX79739.1 - 2.5e-20 72.6 0.0 6.2e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX79739.1 - 0.0059 16.7 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain RE_AlwI PF09491.5 KXX79739.1 - 0.11 10.9 0.1 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 AlwI restriction endonuclease PMT PF02366.13 KXX79740.1 - 2e-80 269.7 17.2 2e-80 269.7 11.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KXX79740.1 - 9e-19 67.7 0.7 3.6e-18 65.7 0.3 1.9 1 1 1 2 2 2 2 MIR domain zf-C2H2 PF00096.21 KXX79741.1 - 0.015 15.5 2.6 0.015 15.5 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX79741.1 - 0.69 10.3 18.6 0.083 13.2 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.2 KXX79742.1 - 7.5e-28 96.7 0.2 7.3e-18 64.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79742.1 - 1.9e-18 65.2 2.4 1.9e-06 27.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KXX79742.1 - 6.6e-15 55.1 5.1 2.5e-06 27.8 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79742.1 - 9.6e-13 47.0 0.5 0.0014 18.6 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat NACHT PF05729.7 KXX79742.1 - 1e-12 48.0 0.2 3.2e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.1 KXX79742.1 - 1.2e-11 44.4 4.1 3.3e-06 27.1 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KXX79742.1 - 3.9e-09 35.8 0.1 1.1e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 KXX79742.1 - 8.4e-06 25.8 0.1 0.00022 21.2 0.0 2.9 4 0 0 4 4 3 1 AAA ATPase domain Arch_ATPase PF01637.13 KXX79742.1 - 0.001 18.8 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KXX79742.1 - 0.0031 17.6 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KXX79742.1 - 0.0035 17.2 0.0 0.079 12.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KXX79742.1 - 0.0093 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF3497 PF12003.3 KXX79742.1 - 0.05 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3497) MSC PF09402.5 KXX79743.1 - 3.1e-104 348.3 0.0 3.6e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF3350 PF11830.3 KXX79743.1 - 0.0088 16.0 2.5 1.6 8.8 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3350) DUF2630 PF10944.3 KXX79743.1 - 1.2 9.3 5.8 1.7 8.8 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2630) TAP_C PF03943.8 KXX79744.1 - 1.5e-12 46.7 0.2 2.7e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 KXX79744.1 - 3.2e-11 42.5 0.6 7.8e-08 31.7 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KXX79744.1 - 8.6e-07 28.1 0.7 0.025 14.5 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.1 KXX79744.1 - 5.3e-06 26.0 0.9 2e-05 24.2 0.4 2.1 1 1 1 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 KXX79744.1 - 6.1e-05 22.6 0.2 0.86 9.8 0.2 3.2 2 0 0 2 2 2 2 Leucine Rich repeat LRR_7 PF13504.1 KXX79744.1 - 0.00011 21.7 1.1 0.12 12.6 0.3 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.1 KXX79744.1 - 0.03 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat HEAT_2 PF13646.1 KXX79744.1 - 0.068 13.4 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 HEAT repeats Herpes_gE PF02480.11 KXX79745.1 - 0.00042 18.6 0.1 0.0007 17.9 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_6 PF13964.1 KXX79745.1 - 0.0032 17.5 1.8 1.1 9.5 0.0 4.1 4 0 0 4 4 4 1 Kelch motif DUF1517 PF07466.6 KXX79745.1 - 0.0077 15.2 1.7 0.0077 15.2 1.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1517) FMN_dh PF01070.13 KXX79746.1 - 4.8e-108 361.1 0.5 9.2e-108 360.2 0.4 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KXX79746.1 - 0.00013 20.9 0.2 0.00021 20.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KXX79746.1 - 0.00031 19.7 1.1 0.0016 17.4 0.3 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KXX79746.1 - 0.00084 18.5 3.9 0.0014 17.8 2.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 KXX79746.1 - 0.046 12.7 0.1 0.13 11.2 0.1 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase DRTGG PF07085.7 KXX79746.1 - 0.086 12.4 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 DRTGG domain ThiG PF05690.9 KXX79746.1 - 0.37 9.8 2.9 0.19 10.7 0.2 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DAHP_synth_1 PF00793.15 KXX79747.1 - 4.2e-98 327.3 0.1 5.3e-98 327.0 0.1 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Mu-like_Pro PF10123.4 KXX79747.1 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Mu-like prophage I protein Dynamin_M PF01031.15 KXX79749.1 - 5.6e-114 379.8 0.0 1.5e-113 378.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KXX79749.1 - 1.8e-55 187.3 0.1 5.4e-55 185.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KXX79749.1 - 2.8e-31 107.2 2.8 2.8e-31 107.2 1.9 2.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KXX79749.1 - 0.00055 19.8 0.3 0.0046 16.9 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX79749.1 - 0.013 16.0 0.0 0.05 14.0 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Ligase_CoA PF00549.14 KXX79750.1 - 7.4e-26 90.5 2.8 4.1e-15 55.7 0.0 3.9 4 0 0 4 4 4 3 CoA-ligase CoA_binding PF02629.14 KXX79750.1 - 7.3e-16 58.4 1.2 2.1e-15 56.9 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KXX79750.1 - 7e-07 28.9 0.3 3.1e-05 23.6 0.0 3.1 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.8 KXX79750.1 - 0.015 15.2 1.5 0.027 14.4 1.0 1.5 1 0 0 1 1 1 0 CHCH domain MFS_1 PF07690.11 KXX79751.1 - 3.3e-20 72.1 57.2 3.3e-20 72.1 39.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KXX79751.1 - 0.00012 20.6 16.4 0.00012 20.6 11.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LIM PF00412.17 KXX79752.1 - 2.9e-25 88.0 23.5 6.1e-09 35.8 1.0 3.6 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.4 KXX79752.1 - 0.05 13.0 1.6 0.07 12.6 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rad60-SLD PF11976.3 KXX79753.1 - 2.9e-19 68.5 0.1 3.6e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KXX79753.1 - 8.2e-09 34.7 0.1 1e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 KXX79753.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) HH_signal PF01085.13 KXX79753.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF1903 PF08991.5 KXX79754.1 - 1.3e-25 89.2 6.2 1.6e-25 89.0 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KXX79754.1 - 0.00077 19.3 5.4 0.00077 19.3 3.7 1.7 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 KXX79754.1 - 0.07 12.9 2.1 0.07 12.9 1.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUFB10 PF10249.4 KXX79754.1 - 0.14 12.2 1.3 0.17 12.0 0.9 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 zf-C4 PF00105.13 KXX79754.1 - 0.58 10.4 4.5 0.38 11.0 1.4 1.9 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) Nup84_Nup100 PF04121.8 KXX79755.1 - 7.6e-66 222.2 0.7 1.1e-64 218.4 0.5 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Cytochrom_C1 PF02167.10 KXX79756.1 - 3.1e-82 275.4 0.0 3.8e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KXX79756.1 - 0.0032 17.5 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KXX79756.1 - 0.05 14.4 0.0 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c Pro_isomerase PF00160.16 KXX79757.1 - 1.4e-50 171.4 0.7 3.3e-50 170.2 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KXX79757.1 - 9.3e-14 50.6 0.6 1.3e-07 31.1 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat adh_short PF00106.20 KXX79758.1 - 7.7e-26 90.9 0.0 9.6e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX79758.1 - 1.2e-25 90.7 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX79758.1 - 2.3e-10 40.4 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KXX79758.1 - 0.0038 16.4 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KXX79758.1 - 0.0047 16.6 0.1 0.0096 15.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HhH-GPD PF00730.20 KXX79759.1 - 2.1e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-B_box PF00643.19 KXX79760.1 - 0.0008 19.2 5.7 0.0019 18.0 4.0 1.7 1 0 0 1 1 1 1 B-box zinc finger NOA36 PF06524.7 KXX79760.1 - 0.13 11.4 4.7 0.21 10.7 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.22 KXX79761.1 - 6.3e-52 175.5 0.0 5.4e-32 110.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX79761.1 - 1.5e-22 80.3 34.5 5.4e-17 62.0 13.9 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KXX79761.1 - 3.3e-08 33.0 0.0 0.0072 15.5 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KXX79761.1 - 4.1e-07 29.5 0.1 0.2 11.0 0.0 3.8 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KXX79761.1 - 9.3e-07 28.2 0.6 0.033 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX79761.1 - 9.7e-06 26.0 0.6 0.0075 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX79761.1 - 8.3e-05 22.7 0.0 3.3 7.8 0.0 3.8 4 0 0 4 4 3 2 AAA domain DUF87 PF01935.12 KXX79761.1 - 0.00019 21.3 5.1 0.011 15.5 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_10 PF12846.2 KXX79761.1 - 0.00036 20.0 0.7 4.8 6.5 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 KXX79761.1 - 0.00036 20.5 1.2 0.77 9.7 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KXX79761.1 - 0.00041 21.1 0.0 0.21 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KXX79761.1 - 0.00048 20.1 1.4 8 6.3 0.0 3.6 3 1 1 4 4 4 0 AAA domain T2SE PF00437.15 KXX79761.1 - 0.00055 18.9 0.2 0.045 12.6 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KXX79761.1 - 0.00095 19.1 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KXX79761.1 - 0.0018 17.4 0.1 0.27 10.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KXX79761.1 - 0.0029 17.9 0.1 2.3 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KXX79761.1 - 0.0066 16.9 0.0 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Mg_chelatase PF01078.16 KXX79761.1 - 0.018 14.2 0.2 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KXX79761.1 - 0.023 13.4 2.2 0.094 11.4 0.0 2.5 3 0 0 3 3 3 0 ArgK protein NACHT PF05729.7 KXX79761.1 - 0.025 14.2 1.3 2.7 7.6 0.4 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 KXX79761.1 - 0.039 13.0 0.7 2.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 KXX79761.1 - 0.057 12.3 0.2 0.58 9.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.1 KXX79761.1 - 0.079 12.8 0.0 4.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KXX79761.1 - 0.11 11.9 0.1 8.4 5.7 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 KXX79761.1 - 0.23 10.8 0.1 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KXX79761.1 - 2.3 6.9 4.0 3.7 6.3 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain p450 PF00067.17 KXX79762.1 - 1.9e-80 270.6 0.0 2.5e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1506 PF07405.6 KXX79762.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) Myb_DNA-bind_6 PF13921.1 KXX79763.1 - 3.4e-05 23.8 0.1 5.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KXX79763.1 - 0.0017 18.3 0.3 0.0041 17.1 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.3 KXX79763.1 - 2.3 8.1 4.1 0.42 10.5 0.1 1.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribonuc_L-PSP PF01042.16 KXX79764.1 - 4.2e-38 129.8 0.2 4.9e-38 129.5 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP SR-25 PF10500.4 KXX79765.1 - 4.5 6.6 7.3 6.9 6.0 4.8 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Alpha-amylase PF00128.19 KXX79767.1 - 4.8e-65 220.0 0.0 6.4e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 KXX79767.1 - 5.2e-27 93.2 0.3 1.2e-26 92.1 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 KXX79767.1 - 1.2e-24 86.2 0.5 3.1e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 KXX79767.1 - 0.00027 19.8 0.1 0.00034 19.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 IL34 PF15036.1 KXX79767.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin 34 Fungal_trans PF04082.13 KXX79768.1 - 7.2e-20 70.9 1.1 8.4e-20 70.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pax2_C PF12403.3 KXX79768.1 - 0.022 14.4 1.5 0.056 13.0 1.1 1.6 1 0 0 1 1 1 0 Paired-box protein 2 C terminal Glutaredoxin PF00462.19 KXX79769.1 - 2.6e-17 62.5 0.0 1.1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KXX79769.1 - 4.3e-13 48.8 0.0 8.9e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX79769.1 - 0.088 12.9 0.0 17 5.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like SH3_9 PF14604.1 KXX79770.1 - 1.3e-31 107.8 2.7 2.6e-15 55.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KXX79770.1 - 7.3e-27 92.5 3.9 5.3e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KXX79770.1 - 1.2e-16 59.9 0.0 1.1e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KXX79770.1 - 4.5e-12 45.9 0.0 7.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mod_r PF07200.8 KXX79771.1 - 3.8e-10 39.8 2.6 7.9e-10 38.8 1.8 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SR-25 PF10500.4 KXX79774.1 - 0.23 10.8 7.7 0.23 10.9 5.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KXX79774.1 - 0.34 10.9 8.7 0.37 10.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CLASP_N PF12348.3 KXX79775.1 - 2.4e-136 452.3 0.4 5.9e-89 297.3 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KXX79775.1 - 8e-07 28.6 0.0 0.37 11.0 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KXX79775.1 - 1.1e-05 25.6 0.1 0.04 14.2 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KXX79775.1 - 0.00067 20.0 0.1 1.8 9.1 0.0 3.4 2 0 0 2 2 2 2 HEAT-like repeat UME PF08064.8 KXX79775.1 - 0.024 14.5 0.1 0.4 10.6 0.0 2.9 3 0 0 3 3 3 0 UME (NUC010) domain Adaptin_N PF01602.15 KXX79775.1 - 0.032 12.5 0.0 0.55 8.4 0.0 2.4 1 1 1 2 2 2 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KXX79775.1 - 0.15 12.4 0.0 10 6.6 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region BSP PF04450.7 KXX79776.1 - 1.5e-78 262.9 0.0 1.7e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KXX79776.1 - 6.5e-06 26.2 0.1 0.00038 20.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 KXX79776.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 SprT-like family rRNA_processing PF08524.6 KXX79777.1 - 0.0002 21.2 0.5 0.0002 21.2 0.3 2.3 2 0 0 2 2 2 1 rRNA processing CAF-1_p150 PF11600.3 KXX79777.1 - 0.00086 18.7 8.7 0.00086 18.7 6.0 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tymo_45kd_70kd PF03251.8 KXX79777.1 - 0.0016 17.2 8.0 0.0021 16.7 5.6 1.2 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein CytochromB561_N PF09786.4 KXX79777.1 - 0.11 10.9 1.3 0.14 10.6 0.5 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal PAT1 PF09770.4 KXX79777.1 - 9.7 4.2 21.0 11 4.0 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RhoGAP PF00620.22 KXX79778.1 - 6e-22 77.8 0.0 6e-22 77.8 0.0 2.6 2 1 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KXX79778.1 - 9.4e-14 51.2 18.5 4.9e-09 36.1 1.6 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 KXX79778.1 - 0.93 9.5 17.0 0.68 9.9 0.8 4.0 4 0 0 4 4 4 0 Zinc ribbon domain SlyX PF04102.7 KXX79778.1 - 3.7 7.9 11.5 0.056 13.8 1.1 2.8 2 1 1 3 3 3 0 SlyX Metal_resist PF13801.1 KXX79778.1 - 8.3 6.4 13.4 0.71 9.8 4.4 2.5 2 0 0 2 2 2 0 Heavy-metal resistance GTP_EFTU PF00009.22 KXX79779.1 - 5.8e-62 208.4 0.1 8.1e-62 207.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KXX79779.1 - 2.4e-37 127.1 0.0 8.6e-37 125.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KXX79779.1 - 2.3e-21 75.4 0.0 5.7e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KXX79779.1 - 2e-12 47.0 2.5 3.4e-12 46.2 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KXX79779.1 - 4.8e-12 45.5 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KXX79779.1 - 2.1e-05 24.4 0.1 4.3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4210 PF13915.1 KXX79780.1 - 2.8e-24 85.1 0.1 8.2e-24 83.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KXX79780.1 - 3.9e-22 77.8 0.9 1e-21 76.5 0.6 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Iso_dh PF00180.15 KXX79781.1 - 4e-97 325.2 0.0 5.1e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 KXX79782.1 - 3.2e-33 114.9 0.0 7.6e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 KXX79782.1 - 0.00018 21.2 2.2 0.00048 19.9 0.0 2.8 3 0 0 3 3 3 1 Vps51/Vps67 PPV_E1_N PF00524.13 KXX79782.1 - 0.31 11.2 3.1 0.2 11.8 0.4 1.9 2 0 0 2 2 2 0 E1 Protein, N terminal domain DUF2415 PF10313.4 KXX79783.1 - 1.5e-15 56.5 0.0 3.4e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Serglycin PF04360.7 KXX79783.1 - 0.0013 18.5 7.7 0.0015 18.3 4.2 1.9 2 0 0 2 2 2 1 Serglycin HSP70 PF00012.15 KXX79784.1 - 6.5e-267 886.3 15.9 7.5e-267 886.1 11.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX79784.1 - 5.2e-15 54.8 4.6 4.2e-13 48.5 0.8 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KXX79784.1 - 3.4e-05 23.5 0.1 0.00065 19.3 0.0 2.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KXX79784.1 - 0.0094 15.0 1.3 1.4 7.9 0.0 3.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KXX79784.1 - 0.013 15.3 9.8 22 4.9 4.0 4.6 2 1 0 2 2 2 0 Cell division protein FtsA DUF3080 PF11279.3 KXX79784.1 - 0.039 13.0 0.2 0.068 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) RRM_6 PF14259.1 KXX79786.1 - 8.6e-12 44.8 0.2 3e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX79786.1 - 2.5e-09 36.8 0.2 8.1e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX79786.1 - 6.4e-08 32.1 1.4 7.9e-07 28.6 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KXX79786.1 - 2e-07 30.9 0.0 5.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 KXX79786.1 - 0.00016 21.2 2.8 0.0003 20.4 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 KXX79786.1 - 0.0016 18.2 0.2 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1330) Nup35_RRM_2 PF14605.1 KXX79786.1 - 0.0081 15.9 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Caudo_TAP PF02413.12 KXX79786.1 - 0.15 12.2 4.8 0.12 12.5 1.5 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein RRM_3 PF08777.6 KXX79786.1 - 0.36 10.6 7.7 1.4 8.7 0.0 3.2 3 0 0 3 3 2 0 RNA binding motif V_ATPase_I PF01496.14 KXX79786.1 - 2.9 5.6 3.3 4.1 5.1 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.1 KXX79786.1 - 5.5 6.0 11.8 9 5.3 8.2 1.2 1 0 0 1 1 1 0 TMCO5 family MTHFR PF02219.12 KXX79788.1 - 9.9e-113 375.9 0.0 1.6e-112 375.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PPR_2 PF13041.1 KXX79790.1 - 3.5e-16 58.9 3.8 7.1e-07 29.0 0.0 5.9 3 1 4 7 7 7 4 PPR repeat family PPR PF01535.15 KXX79790.1 - 8.1e-12 44.2 5.1 1.8e-05 24.4 0.0 7.1 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 KXX79790.1 - 6.3e-07 28.7 0.0 0.0003 20.2 0.0 3.4 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 KXX79790.1 - 7.3e-06 26.1 3.7 1.2 9.9 0.0 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat PPR_3 PF13812.1 KXX79790.1 - 7.5e-06 25.8 15.0 0.38 11.1 0.0 8.5 9 0 0 9 9 9 2 Pentatricopeptide repeat domain ATP13 PF12921.2 KXX79790.1 - 0.023 14.0 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_2 PF07719.12 KXX79790.1 - 0.073 13.0 2.3 6.2 6.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.9 KXX79791.1 - 1.4e-42 145.5 0.0 1.6e-32 112.5 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KXX79791.1 - 0.0032 17.2 0.0 0.0077 15.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KXX79791.1 - 0.0067 16.0 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 KXX79791.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 KXX79791.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein zf-BED PF02892.10 KXX79792.1 - 0.057 13.1 0.4 0.057 13.1 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KXX79792.1 - 1.3 8.9 5.5 0.34 10.8 0.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.13 KXX79792.1 - 5.7 6.9 13.6 0.24 11.3 5.5 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KXX79794.1 - 2.1e-12 47.2 0.0 4.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79794.1 - 5.8e-10 38.4 0.1 2.6e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 KXX79794.1 - 1.3e-07 31.4 0.6 7.9e-07 28.8 0.1 2.4 2 0 0 2 2 2 1 NACHT domain Ank_3 PF13606.1 KXX79794.1 - 1.6e-07 30.9 0.0 0.0024 17.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KXX79794.1 - 5.1e-07 29.7 0.0 2.3e-06 27.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX79794.1 - 4.2e-06 27.1 0.0 1.4e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 KXX79794.1 - 0.00027 20.9 0.1 0.0011 18.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 KXX79794.1 - 0.0032 16.7 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KXX79794.1 - 0.0048 16.5 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 KXX79794.1 - 0.01 15.9 0.0 0.041 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 KXX79794.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_18 PF13238.1 KXX79794.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KXX79794.1 - 0.2 11.0 0.1 0.55 9.6 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain cobW PF02492.14 KXX79794.1 - 0.26 10.7 0.1 0.47 9.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 KXX79794.1 - 0.37 9.7 1.0 9.8 5.0 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA PF00004.24 KXX79795.1 - 3e-17 63.0 0.0 9.3e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX79795.1 - 0.0056 16.6 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 KXX79795.1 - 0.022 15.0 0.4 0.12 12.6 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KXX79795.1 - 0.19 11.8 1.5 0.82 9.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain Solute_trans_a PF03619.11 KXX79796.1 - 1.3e-106 355.9 5.2 1.5e-106 355.7 3.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF373 PF04123.8 KXX79796.1 - 2.9 6.8 4.5 0.49 9.3 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Na_Ca_ex PF01699.19 KXX79797.1 - 2e-11 43.6 11.7 3.2e-10 39.7 7.0 2.4 1 1 1 2 2 2 1 Sodium/calcium exchanger protein Mid2 PF04478.7 KXX79797.1 - 0.42 10.0 4.9 0.13 11.6 1.0 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF3608 PF12257.3 KXX79798.1 - 1.2e-62 211.3 0.1 5e-60 202.7 0.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KXX79798.1 - 8.4e-29 99.1 0.1 2.1e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 KXX79799.1 - 1.2e-36 126.3 2.1 9.7e-33 113.4 0.3 2.0 1 1 1 2 2 2 2 Cation efflux family DUF2776 PF10951.3 KXX79799.1 - 0.099 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) HhH-GPD PF00730.20 KXX79800.1 - 2.1e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3413 PF11893.3 KXX79801.1 - 0.0073 15.2 0.5 0.0073 15.2 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3413) UPF0016 PF01169.14 KXX79801.1 - 0.29 11.2 7.6 4.5 7.4 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF2919 PF11143.3 KXX79801.1 - 1.2 8.9 6.5 0.31 10.8 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) adh_short PF00106.20 KXX79802.1 - 7.7e-26 90.9 0.0 9.6e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX79802.1 - 1.2e-25 90.7 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX79802.1 - 2.3e-10 40.4 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KXX79802.1 - 0.0038 16.4 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KXX79802.1 - 0.0047 16.6 0.1 0.0096 15.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Uricase PF01014.13 KXX79803.1 - 6.1e-84 279.0 0.9 9.5e-46 155.3 0.3 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KXX79803.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme RICTOR_N PF14664.1 KXX79804.1 - 9.5e-139 462.0 3.0 3.7e-137 456.8 0.3 2.6 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KXX79804.1 - 1.1e-91 305.9 0.0 1.7e-90 302.0 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KXX79804.1 - 2.1e-43 146.9 0.0 9e-42 141.6 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KXX79804.1 - 8.9e-27 92.8 2.2 1e-25 89.4 0.1 3.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KXX79804.1 - 2.9e-14 52.5 7.3 7.9e-14 51.1 5.1 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 KXX79804.1 - 7.1e-06 26.2 0.2 0.39 11.0 0.0 5.4 5 0 0 5 5 5 1 HEAT repeats Uds1 PF15456.1 KXX79804.1 - 0.0086 16.0 8.6 0.0086 16.0 5.9 2.9 2 0 0 2 2 2 1 Up-regulated During Septation IncA PF04156.9 KXX79804.1 - 2.2 7.8 21.7 0.025 14.2 3.0 2.6 2 0 0 2 2 2 0 IncA protein FAR1 PF03101.10 KXX79805.1 - 0.00021 21.7 0.7 0.00021 21.7 0.5 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain Matrilin_ccoil PF10393.4 KXX79805.1 - 0.0076 15.5 1.0 0.072 12.4 0.2 2.3 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin AFT PF08731.6 KXX79805.1 - 0.3 11.2 3.1 0.21 11.7 0.2 2.0 2 0 0 2 2 2 0 Transcription factor AFT BAF1_ABF1 PF04684.8 KXX79805.1 - 3 6.5 11.2 4.6 5.9 7.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_11 PF13414.1 KXX79806.1 - 4.2e-20 71.1 10.8 7.7e-10 38.2 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KXX79806.1 - 3e-17 61.4 10.9 1.9e-07 30.3 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KXX79806.1 - 2.4e-15 55.1 6.4 5.3e-05 22.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KXX79806.1 - 2.1e-10 39.6 4.6 0.0003 20.3 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX79806.1 - 1.4e-08 34.5 1.8 5.8e-05 22.9 0.0 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX79806.1 - 4.8e-07 29.1 0.3 0.00042 19.9 0.0 4.0 2 2 1 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.19 KXX79806.1 - 1.3e-06 27.9 0.1 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.1 KXX79806.1 - 2.4e-06 27.5 1.6 0.55 10.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX79806.1 - 5e-06 27.0 1.0 0.013 16.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KXX79806.1 - 7.6e-06 25.6 3.2 0.094 12.5 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX79806.1 - 9e-06 25.5 0.6 0.025 14.7 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX79806.1 - 0.00045 20.5 0.1 0.5 11.1 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX79806.1 - 0.0067 16.5 3.1 0.011 15.8 0.2 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HMA PF00403.21 KXX79807.1 - 1e-12 48.0 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KXX79807.1 - 1.8e-10 41.1 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.13 KXX79808.1 - 5.7e-37 126.6 0.0 8.4e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 CMAS PF02353.15 KXX79809.1 - 3.8e-62 209.8 0.1 4.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KXX79809.1 - 8.6e-12 45.0 0.0 2.9e-11 43.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79809.1 - 5.2e-07 30.0 0.0 1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79809.1 - 0.002 18.6 0.0 0.0096 16.4 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX79809.1 - 0.0028 17.9 0.0 0.0086 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX79809.1 - 0.0095 15.9 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79809.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79809.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KXX79809.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KXX79809.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 KXX79809.1 - 0.063 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF498 PF04430.9 KXX79810.1 - 1.2e-22 79.5 0.0 1.9e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) LAT PF15234.1 KXX79810.1 - 2.3 7.6 7.5 3 7.2 5.2 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Ribosomal_L34e PF01199.13 KXX79811.1 - 5.9e-37 125.7 2.6 8e-37 125.3 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 KXX79811.1 - 2.9 7.6 7.0 2.5 7.8 0.2 2.9 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Colicin_Pyocin PF01320.13 KXX79812.1 - 0.063 13.1 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Clathrin_lg_ch PF01086.12 KXX79812.1 - 0.13 12.1 2.9 0.15 11.9 2.0 1.1 1 0 0 1 1 1 0 Clathrin light chain DEAD PF00270.24 KXX79813.1 - 6e-46 156.0 0.0 1.9e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX79813.1 - 1.4e-28 98.5 0.0 2.7e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX79813.1 - 7.5e-05 22.6 0.0 0.00031 20.6 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KXX79813.1 - 0.0019 16.6 0.0 0.069 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KXX79813.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Phos_pyr_kin PF08543.7 KXX79814.1 - 1.3e-78 263.6 0.9 1.4e-39 135.7 0.0 2.6 3 0 0 3 3 3 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KXX79814.1 - 4e-51 173.7 0.2 5.4e-51 173.3 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KXX79814.1 - 2.9e-08 33.2 0.1 5.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 KXX79814.1 - 0.026 13.8 0.1 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate kinase AAR2 PF05282.6 KXX79815.1 - 1.4e-36 126.1 0.0 1e-24 87.1 0.0 2.1 1 1 1 2 2 2 2 AAR2 protein SSP160 PF06933.6 KXX79815.1 - 0.081 10.8 2.1 0.11 10.4 1.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TT_ORF2 PF02957.10 KXX79816.1 - 0.46 11.1 4.7 1.1 9.9 3.3 1.7 1 0 0 1 1 1 0 TT viral ORF2 DUF1682 PF07946.9 KXX79816.1 - 7.6 5.2 7.0 10 4.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Mpv17_PMP22 PF04117.7 KXX79817.1 - 7.2e-12 44.7 3.8 2.1e-10 40.0 2.0 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1275 PF06912.6 KXX79817.1 - 0.057 12.6 3.6 0.5 9.5 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1275) Gly-zipper_OmpA PF13436.1 KXX79817.1 - 0.33 10.6 3.9 0.82 9.3 2.7 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain EAP30 PF04157.11 KXX79818.1 - 8.4e-54 182.0 0.0 2.1e-53 180.7 0.0 1.6 1 1 0 1 1 1 1 EAP30/Vps36 family Hemerythrin PF01814.18 KXX79819.1 - 2.2e-10 40.8 12.9 1.3e-05 25.3 3.6 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain CCDC66 PF15236.1 KXX79819.1 - 0.34 10.5 5.1 0.53 9.8 3.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Myb_DNA-bind_6 PF13921.1 KXX79821.1 - 2.4e-15 56.3 0.2 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KXX79821.1 - 5.5e-12 45.5 0.1 0.00014 21.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 KXX79821.1 - 0.1 12.1 0.1 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain SNF2_N PF00176.18 KXX79822.1 - 4e-67 226.1 0.0 6.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX79822.1 - 1e-15 57.3 0.0 2.8e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KXX79822.1 - 6.6e-05 21.8 0.0 0.00019 20.3 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KXX79822.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LON PF02190.11 KXX79823.1 - 1.8e-23 83.2 0.0 2.8e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KXX79823.1 - 3e-09 36.7 8.5 6.6e-09 35.6 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX79823.1 - 7.4e-09 35.1 5.3 1.5e-08 34.1 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX79823.1 - 2.4e-08 33.6 8.9 4.9e-08 32.6 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KXX79823.1 - 4.7e-08 32.5 6.5 9.2e-08 31.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX79823.1 - 4.9e-07 29.3 6.1 1e-06 28.3 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX79823.1 - 6.3e-07 29.1 9.3 1.4e-06 28.0 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KXX79823.1 - 6.1e-05 22.6 4.5 0.00014 21.5 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 KXX79823.1 - 0.00036 20.4 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.1 KXX79823.1 - 0.0033 16.9 6.7 0.012 15.1 4.6 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KXX79823.1 - 0.0075 15.7 2.2 0.02 14.3 1.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KXX79823.1 - 0.013 15.5 1.5 0.036 14.1 1.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 KXX79823.1 - 0.32 10.4 6.8 0.17 11.4 2.9 1.9 2 0 0 2 2 2 0 P-11 zinc finger SOCS_box PF07525.11 KXX79823.1 - 1.1 9.1 8.2 1.7 8.5 2.6 3.0 3 0 0 3 3 3 0 SOCS box Prok-RING_4 PF14447.1 KXX79823.1 - 5.1 6.7 9.0 35 4.0 6.3 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 efThoc1 PF11957.3 KXX79825.1 - 3.2e-167 556.9 0.1 3.9e-167 556.6 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KXX79825.1 - 1.5e-26 92.9 0.0 2.8e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase AAA_11 PF13086.1 KXX79826.1 - 9e-23 81.0 0.0 2.2e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KXX79826.1 - 2.5e-22 79.2 0.0 4.4e-21 75.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX79826.1 - 3.2e-09 36.3 0.0 6e-08 32.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KXX79826.1 - 2.1e-07 30.7 0.0 0.0034 16.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KXX79826.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KXX79826.1 - 0.00072 19.0 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KXX79826.1 - 0.002 18.3 0.0 0.0062 16.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX79826.1 - 0.0068 16.5 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KXX79826.1 - 0.0079 15.7 0.1 0.44 10.0 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KXX79826.1 - 0.0095 15.4 0.0 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KXX79826.1 - 0.017 15.1 0.9 0.1 12.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 KXX79826.1 - 0.021 15.6 0.0 0.87 10.4 0.0 3.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KXX79826.1 - 0.026 13.6 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KXX79826.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DnaB_C PF03796.10 KXX79826.1 - 0.044 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 KXX79826.1 - 0.046 12.6 0.8 0.073 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KXX79826.1 - 0.12 11.2 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.16 KXX79826.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RNA_helicase PF00910.17 KXX79826.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 KXX79826.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 KXX79826.1 - 0.31 9.9 0.0 19 4.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase HSA PF07529.8 KXX79827.1 - 4.7e-19 67.9 0.6 4.7e-19 67.9 0.4 3.8 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KXX79827.1 - 2.3e-13 50.0 1.7 2.8e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KXX79827.1 - 0.0066 16.4 0.1 0.019 15.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4407 PF14362.1 KXX79827.1 - 8.4 5.2 29.9 0.075 11.9 4.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Abhydrolase_3 PF07859.8 KXX79828.1 - 0.0089 15.6 2.5 0.013 15.0 1.8 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TAP42 PF04177.7 KXX79828.1 - 0.038 12.9 3.6 0.053 12.4 2.5 1.2 1 0 0 1 1 1 0 TAP42-like family DUF3801 PF12687.2 KXX79828.1 - 0.26 10.8 3.3 0.35 10.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) FdhE PF04216.7 KXX79828.1 - 0.37 10.4 8.7 0.45 10.1 6.0 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation PAT1 PF09770.4 KXX79828.1 - 2 6.5 21.4 2 6.5 14.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDDD PF10161.4 KXX79828.1 - 2.1 7.9 4.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein TFIIA PF03153.8 KXX79828.1 - 5.2 6.8 16.9 6.3 6.5 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIC3 PF15361.1 KXX79828.1 - 5.8 7.1 8.2 7.5 6.7 5.7 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 KXX79828.1 - 6.8 6.3 10.4 8.3 6.0 7.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3123 PF11321.3 KXX79828.1 - 8.4 6.7 8.8 4.4 7.6 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) WD40 PF00400.27 KXX79829.1 - 7.5e-15 54.1 0.1 0.00089 19.0 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat INSIG PF07281.7 KXX79830.1 - 7.8e-50 168.9 2.2 1.2e-49 168.3 1.5 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Alpha-amylase PF00128.19 KXX79831.1 - 1.1e-100 337.0 0.2 2e-100 336.2 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KXX79831.1 - 0.033 13.0 0.1 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme YopX PF09643.5 KXX79831.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 YopX protein G-patch_2 PF12656.2 KXX79832.1 - 1.5e-16 60.0 2.4 3.7e-16 58.7 0.1 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site Pro-kuma_activ PF09286.6 KXX79833.1 - 1.7e-44 151.3 0.0 2.9e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KXX79833.1 - 0.0045 16.1 0.1 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Asp PF00026.18 KXX79834.1 - 4.5e-58 196.9 1.4 5.4e-58 196.7 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX79834.1 - 3.7e-08 33.5 0.2 6.7e-07 29.4 0.0 2.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KXX79834.1 - 5.9e-05 23.4 0.0 0.46 11.0 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KXX79834.1 - 0.015 14.8 0.1 0.12 11.9 0.1 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KXX79834.1 - 0.042 13.6 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1966 PF09260.6 KXX79835.1 - 4.8e-13 49.0 0.1 1.2e-12 47.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 KXX79835.1 - 6.5e-06 25.7 0.1 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.11 KXX79836.1 - 3.1e-24 85.3 23.7 3.1e-24 85.3 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.19 KXX79837.1 - 1.1e-37 130.0 0.2 1.5e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain COesterase PF00135.23 KXX79838.1 - 1.9e-94 317.3 0.0 2.7e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX79838.1 - 0.0029 17.2 0.2 0.0098 15.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX79838.1 - 0.035 13.3 0.5 0.18 11.0 0.5 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family 2OG-FeII_Oxy PF03171.15 KXX79840.1 - 6.1e-05 23.2 0.0 0.00015 21.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KXX79840.1 - 0.02 15.3 0.1 0.047 14.2 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_10 PF13460.1 KXX79842.1 - 1.5e-14 54.4 0.0 2.2e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX79842.1 - 2.3e-07 30.3 0.0 3.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KXX79842.1 - 0.002 17.5 0.0 0.0076 15.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.4 KXX79842.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 PAC2 family Thioredoxin_6 PF13848.1 KXX79843.1 - 2e-18 66.8 0.0 2.4e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KXX79843.1 - 1.2e-07 31.3 0.0 6.2e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX79843.1 - 0.069 13.3 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Hist_deacetyl PF00850.14 KXX79844.1 - 1.2e-76 257.9 0.0 2.2e-76 257.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_4 PF08386.5 KXX79845.1 - 6.3e-19 67.7 0.0 1.4e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX79845.1 - 3.1e-08 33.4 0.0 3e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX79845.1 - 6.3e-06 26.2 5.1 0.00013 21.9 3.5 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1212 PF06738.7 KXX79846.1 - 2.9e-55 186.7 4.6 3.1e-53 180.1 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KXX79846.1 - 3.7e-21 75.4 29.6 3e-12 46.6 1.9 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3815) Peptidase_A4 PF01828.12 KXX79847.1 - 5.4e-65 218.3 3.0 6.5e-65 218.0 2.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF2946 PF11162.3 KXX79847.1 - 0.069 13.3 2.4 0.12 12.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) RNase_PH PF01138.16 KXX79848.1 - 2.2e-35 121.8 0.0 3.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KXX79848.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 JAB PF01398.16 KXX79851.1 - 1.2e-34 118.5 0.0 2.3e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KXX79851.1 - 2.3e-26 92.1 1.3 2.3e-26 92.1 0.9 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KXX79851.1 - 7.7e-09 35.0 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF605 PF04652.11 KXX79852.1 - 6.4e-97 325.3 16.7 7.8e-97 325.0 11.6 1.0 1 0 0 1 1 1 1 Vta1 like DUF812 PF05667.6 KXX79852.1 - 0.11 10.9 2.6 0.15 10.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Thioredoxin PF00085.15 KXX79853.1 - 1.6e-31 108.0 0.1 2.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KXX79853.1 - 3.9e-09 36.5 0.0 2.2e-07 30.8 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KXX79853.1 - 1.4e-07 31.6 1.9 5e-05 23.4 1.3 3.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX79853.1 - 6e-06 26.2 0.2 0.0061 16.6 0.0 4.5 3 3 2 5 5 5 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KXX79853.1 - 0.0048 16.8 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like FAIM1 PF06905.8 KXX79853.1 - 0.0051 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Thioredoxin_3 PF13192.1 KXX79853.1 - 0.076 12.8 0.2 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain HyaE PF07449.6 KXX79853.1 - 0.11 12.4 0.0 0.86 9.5 0.0 2.5 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE p450 PF00067.17 KXX79854.1 - 1.5e-68 231.4 0.0 1.7e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.19 KXX79855.1 - 3.4e-50 171.4 0.0 6.4e-50 170.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX79855.1 - 2.5e-09 37.0 0.0 1.3e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX79855.1 - 0.002 18.1 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX79855.1 - 0.0051 15.9 0.1 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KXX79855.1 - 0.0085 15.1 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KXX79855.1 - 0.0095 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KXX79855.1 - 0.019 13.4 0.2 0.031 12.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KXX79855.1 - 0.026 13.4 0.0 0.077 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase YopE_N PF09020.5 KXX79856.1 - 0.093 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 YopE, N terminal Abhydrolase_4 PF08386.5 KXX79857.1 - 1.8e-21 75.9 0.0 3.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX79857.1 - 1.9e-13 50.5 0.0 5.9e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX79857.1 - 9.7e-06 25.6 0.0 4.1e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79857.1 - 0.0073 16.0 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Gcd10p PF04189.8 KXX79858.1 - 1e-71 241.5 0.0 1.3e-70 237.8 0.0 2.1 1 1 0 1 1 1 1 Gcd10p family Glyco_hydro_76 PF03663.9 KXX79859.1 - 2.9e-143 477.7 0.4 3.7e-143 477.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 P21-Arc PF04062.9 KXX79861.1 - 1.4e-77 259.4 0.0 1.7e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Barwin PF00967.12 KXX79862.1 - 3.3 7.3 9.5 18 5.0 1.1 4.2 2 1 2 4 4 4 0 Barwin family HET PF06985.6 KXX79863.1 - 3.4e-14 53.1 0.2 2.4e-12 47.1 0.0 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Terpene_synth_C PF03936.11 KXX79864.1 - 1.8e-11 43.7 0.0 2.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FAD-oxidase_C PF02913.14 KXX79865.1 - 4.7e-57 193.1 0.0 7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KXX79865.1 - 3.7e-39 133.3 0.0 7.2e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KXX79866.1 - 7.8e-89 298.3 0.1 9e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX79866.1 - 4.3e-07 29.8 0.0 2.2e-06 27.6 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KXX79866.1 - 1.3e-05 24.2 0.1 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KXX79866.1 - 5.6e-05 21.7 0.9 0.0016 17.0 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KXX79866.1 - 5.8e-05 23.0 0.0 0.002 18.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX79866.1 - 8.4e-05 21.7 0.1 0.00033 19.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KXX79866.1 - 0.00012 21.1 0.3 0.00053 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KXX79866.1 - 0.00019 20.6 0.0 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX79866.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KXX79866.1 - 0.0021 17.2 0.0 0.0055 15.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX79866.1 - 0.0046 17.0 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX79866.1 - 0.025 13.5 0.2 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.19 KXX79867.1 - 9.6e-103 344.1 33.6 1.2e-102 343.8 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX79867.1 - 2.6e-25 88.8 36.1 2.3e-22 79.2 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PEPcase_2 PF14010.1 KXX79868.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Methyltransf_23 PF13489.1 KXX79869.1 - 8.2e-24 84.1 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX79869.1 - 8.3e-10 39.2 0.0 1.1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX79869.1 - 3.7e-08 33.7 0.0 2.3e-07 31.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX79869.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX79869.1 - 4.6e-07 29.5 0.0 3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX79869.1 - 9.7e-07 29.0 0.0 2.9e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX79869.1 - 0.0024 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KXX79869.1 - 0.0037 16.6 0.0 0.021 14.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX79869.1 - 0.014 15.4 0.0 0.051 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KXX79869.1 - 0.054 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Oxysterol_BP PF01237.13 KXX79870.1 - 6.6e-65 218.9 0.0 9.5e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein SAD_SRA PF02182.12 KXX79873.1 - 6.2e-25 87.3 0.1 9.5e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Ank_2 PF12796.2 KXX79874.1 - 6.3e-14 52.0 0.0 2.6e-07 30.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX79874.1 - 3.4e-13 49.3 0.5 4.5e-06 26.7 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX79874.1 - 2.5e-11 43.7 0.8 0.054 14.0 0.0 4.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KXX79874.1 - 7.5e-10 38.1 0.8 3.8e-05 23.2 0.1 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 KXX79874.1 - 4.3e-07 29.5 1.4 0.00049 20.0 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat DUF1399 PF07173.7 KXX79877.1 - 3.5e-18 66.2 10.5 2.1e-15 57.2 0.3 4.1 3 1 2 5 5 5 2 Protein of unknown function (DUF1399) AbiH PF14253.1 KXX79877.1 - 0.082 12.4 1.1 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4200 PF13863.1 KXX79877.1 - 1.6 8.7 14.2 0.022 14.6 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4066 PF13278.1 KXX79880.1 - 3.4e-27 94.7 0.0 4.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX79880.1 - 1.2e-15 57.2 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Pyr_redox_2 PF07992.9 KXX79881.1 - 2.2e-06 27.6 0.0 2.3e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX79881.1 - 0.00017 21.3 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX79881.1 - 0.00028 21.0 0.1 0.11 12.5 0.1 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX79881.1 - 0.0012 17.8 0.2 0.012 14.5 0.3 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Malic_M PF03949.10 KXX79881.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain K_oxygenase PF13434.1 KXX79881.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lactamase_B PF00753.22 KXX79882.1 - 3.8e-18 65.8 6.3 5.6e-18 65.2 4.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KXX79882.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Abhydrolase_6 PF12697.2 KXX79883.1 - 3.6e-17 63.0 0.8 3.6e-17 63.0 0.5 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79883.1 - 8e-15 54.8 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KXX79883.1 - 1.2e-11 43.8 0.0 1.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.15 KXX79883.1 - 1e-08 34.9 0.0 4.1e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 KXX79883.1 - 1e-06 28.3 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KXX79883.1 - 1e-05 24.8 0.1 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KXX79883.1 - 2.7e-05 23.7 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KXX79883.1 - 0.0025 17.4 0.1 0.053 13.0 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KXX79883.1 - 0.0096 15.2 0.0 0.019 14.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_7 PF12715.2 KXX79883.1 - 0.024 13.5 0.3 0.43 9.4 0.0 2.5 3 0 0 3 3 3 0 Abhydrolase family Abhydrolase_3 PF07859.8 KXX79883.1 - 0.029 13.9 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 KXX79883.1 - 0.074 12.2 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase FAD_binding_4 PF01565.18 KXX79885.1 - 4.3e-22 78.0 1.8 9.5e-21 73.7 1.3 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KXX79885.1 - 6.9e-05 22.6 0.1 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Patatin PF01734.17 KXX79887.1 - 6.6e-08 32.7 0.1 9.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase ADH_zinc_N PF00107.21 KXX79889.1 - 1.7e-19 69.6 0.0 2.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX79889.1 - 9.2e-07 29.8 0.0 1.7e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S8 PF00082.17 KXX79891.1 - 2.1e-17 63.1 0.0 3.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 KXX79891.1 - 7.9e-09 35.7 0.1 4.6e-05 23.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX79891.1 - 3.7e-08 33.6 0.2 0.011 16.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79891.1 - 7.1e-07 28.8 0.0 0.0035 17.4 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 KXX79891.1 - 2.8e-05 23.7 0.0 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KXX79891.1 - 4.9e-05 23.4 0.1 0.11 12.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) p450 PF00067.17 KXX79892.1 - 2.6e-65 220.7 0.0 3.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTV_P6 PF06706.6 KXX79892.1 - 0.056 12.9 0.4 0.12 11.8 0.3 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DIT1_PvcA PF05141.7 KXX79893.1 - 1.2e-94 316.7 0.0 1.5e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein adh_short PF00106.20 KXX79894.1 - 1.5e-21 77.0 4.0 1.8e-21 76.7 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX79894.1 - 7.9e-19 68.3 0.0 1.1e-18 67.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX79894.1 - 3.7e-06 26.7 1.4 4.7e-06 26.3 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX79894.1 - 0.0012 18.2 0.1 0.0031 16.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX79894.1 - 0.015 15.0 0.5 0.024 14.2 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KXX79894.1 - 0.015 14.1 1.0 0.027 13.3 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.11 KXX79895.1 - 1.5e-39 135.6 50.5 1.1e-38 132.8 16.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX79895.1 - 9.8e-15 54.0 6.9 9.8e-15 54.0 4.8 2.3 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 KXX79895.1 - 0.08 10.9 6.3 0.096 10.7 0.7 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CFEM PF05730.6 KXX79897.1 - 4.9e-28 96.7 58.2 8.3e-10 38.3 6.7 8.2 5 4 4 9 9 9 4 CFEM domain Patatin PF01734.17 KXX79898.1 - 1.6e-13 51.0 0.1 3.3e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_3 PF13920.1 KXX79898.1 - 0.0036 16.9 3.0 0.01 15.4 2.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX79898.1 - 0.0059 16.2 0.3 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KXX79898.1 - 0.013 15.2 4.6 0.013 15.2 3.2 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 KXX79898.1 - 0.017 14.9 4.6 0.057 13.2 3.2 2.0 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 KXX79898.1 - 0.024 14.1 0.5 0.065 12.7 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 KXX79898.1 - 0.028 14.4 5.9 0.088 12.8 4.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX79898.1 - 0.039 13.8 1.5 0.12 12.2 1.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KXX79898.1 - 4.8 6.9 7.2 0.34 10.5 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 KXX79899.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KXX79899.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KXX79899.1 - 0.0032 17.4 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KXX79899.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KXX79899.1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KXX79899.1 - 0.047 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KXX79899.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 KXX79899.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KXX79899.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain zf-B_box PF00643.19 KXX79899.1 - 0.17 11.7 8.7 0.27 11.1 6.0 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF3176 PF11374.3 KXX79900.1 - 2.1e-19 69.4 0.0 3.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Flavi_NS4A PF01350.12 KXX79900.1 - 0.072 12.6 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A DUF3237 PF11578.3 KXX79902.1 - 5.9e-37 126.2 0.0 8.6e-37 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.13 KXX79903.1 - 8.4e-10 38.3 9.4 1.4e-09 37.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX79903.1 - 2.8e-07 29.6 0.1 4.6e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kinesin PF00225.18 KXX79904.1 - 2.8e-60 203.8 0.0 3.9e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Pectate_lyase PF03211.8 KXX79905.1 - 4.5e-70 235.3 3.9 6e-70 234.9 2.7 1.0 1 0 0 1 1 1 1 Pectate lyase TauD PF02668.11 KXX79906.1 - 5.7e-41 140.8 0.0 7.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PolyA_pol_arg_C PF12626.2 KXX79906.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus SIR2 PF02146.12 KXX79907.1 - 5.4e-25 88.1 0.7 2.8e-18 66.2 0.0 2.9 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 KXX79907.1 - 0.064 13.0 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain YscW PF09619.5 KXX79908.1 - 0.03 14.0 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Type III secretion system lipoprotein chaperone (YscW) FAD_binding_3 PF01494.14 KXX79909.1 - 7.9e-16 58.0 0.6 2e-14 53.4 0.4 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX79909.1 - 1.2e-05 25.2 0.2 2.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX79909.1 - 0.00025 20.0 0.7 0.023 13.5 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX79909.1 - 0.00038 20.8 0.1 0.13 12.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX79909.1 - 0.01 15.7 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KXX79909.1 - 0.014 14.2 0.0 0.17 10.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.19 KXX79909.1 - 0.03 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KXX79909.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX79909.1 - 0.12 11.2 0.0 0.47 9.3 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Ank_2 PF12796.2 KXX79910.1 - 1e-106 349.4 0.1 1.6e-14 53.9 0.1 11.1 5 4 5 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KXX79910.1 - 6.1e-78 253.0 34.9 0.00025 20.7 0.0 22.8 22 1 0 22 22 22 18 Ankyrin repeat Ank_4 PF13637.1 KXX79910.1 - 2.5e-68 225.3 15.2 5.8e-10 39.4 0.1 16.4 7 3 10 17 17 17 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX79910.1 - 6e-64 205.5 15.6 0.00015 21.6 0.0 21.9 22 0 0 22 22 22 16 Ankyrin repeat Ank_5 PF13857.1 KXX79910.1 - 4.9e-56 185.4 32.4 6.8e-07 29.3 0.0 17.7 10 7 9 19 19 19 14 Ankyrin repeats (many copies) ZZ PF00569.12 KXX79910.1 - 4.2e-07 29.3 8.6 8.4e-07 28.4 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-DHHC PF01529.15 KXX79910.1 - 0.0079 15.6 0.6 0.013 14.8 0.4 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase C1_2 PF03107.11 KXX79910.1 - 0.073 13.1 14.1 0.13 12.4 9.8 1.4 1 0 0 1 1 1 0 C1 domain FAM104 PF15434.1 KXX79911.1 - 6.1 7.0 6.2 6.2 7.0 4.0 1.3 1 1 0 1 1 1 0 Family 104 Cyt-b5 PF00173.23 KXX79912.1 - 1.4e-13 50.4 0.0 2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sua5_yciO_yrdC PF01300.13 KXX79912.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination HET PF06985.6 KXX79913.1 - 2.6e-20 72.9 0.0 1.5e-19 70.4 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4033 PF13225.1 KXX79913.1 - 0.0035 16.9 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4033) DUF1295 PF06966.7 KXX79914.1 - 1.2e-37 129.4 7.9 1.5e-37 129.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4149 PF13664.1 KXX79916.1 - 1.3e-22 79.7 2.2 1.3e-22 79.7 1.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF3816 PF12822.2 KXX79916.1 - 0.012 15.4 2.4 0.018 14.9 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF21 PF01595.15 KXX79916.1 - 0.42 9.8 2.8 0.95 8.7 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF21 Ku PF02735.11 KXX79917.1 - 1.8e-27 96.0 0.0 3.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KXX79917.1 - 2e-24 86.2 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KXX79917.1 - 4e-15 55.7 0.0 7.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KXX79917.1 - 0.00018 21.6 0.0 0.00062 19.9 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX79917.1 - 0.0057 16.4 0.1 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain DnaJ PF00226.26 KXX79919.1 - 1.7e-07 30.8 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KXX79919.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Pam16 Glycos_transf_1 PF00534.15 KXX79920.1 - 8.2e-30 103.4 0.0 1.2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KXX79920.1 - 8.9e-16 58.2 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 KXX79920.1 - 1.6e-05 25.1 1.2 0.00012 22.3 0.1 2.6 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.1 KXX79920.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KXX79920.1 - 0.00034 20.8 0.0 0.00071 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SKG6 PF08693.5 KXX79921.1 - 4.6e-10 38.6 2.7 7.4e-10 37.9 1.9 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KXX79921.1 - 5.2e-05 22.8 0.0 6.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) VSP PF03302.8 KXX79921.1 - 0.00037 19.2 0.0 0.00043 19.0 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Epiglycanin_C PF14654.1 KXX79921.1 - 0.0036 17.2 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Herpes_gE PF02480.11 KXX79921.1 - 0.11 10.7 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KXX79921.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2207 PF09972.4 KXX79921.1 - 0.16 10.5 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VPEP PF07589.6 KXX79921.1 - 4 7.4 7.1 1.9 8.5 0.4 2.7 2 0 0 2 2 2 0 PEP-CTERM motif CENP-X PF09415.5 KXX79924.1 - 1.1e-27 95.6 1.0 1.4e-27 95.2 0.1 1.6 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Nop14 PF04147.7 KXX79924.1 - 0.74 7.6 4.9 0.76 7.6 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family DTHCT PF08070.6 KXX79924.1 - 1.6 9.4 7.9 0.17 12.5 1.2 2.1 1 1 1 2 2 2 0 DTHCT (NUC029) region ORC6 PF05460.8 KXX79924.1 - 2.3 7.2 4.3 3.3 6.7 3.0 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Senescence_reg PF04520.8 KXX79924.1 - 2.8 8.4 8.7 12 6.3 3.5 2.2 2 0 0 2 2 2 0 Senescence regulator DUF4604 PF15377.1 KXX79924.1 - 5.3 7.2 12.5 3.5 7.8 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Mito_carr PF00153.22 KXX79925.1 - 8.6e-68 224.1 4.4 1.4e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.19 KXX79926.1 - 3.7e-11 42.9 0.2 7.7e-09 35.4 0.2 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX79926.1 - 1.3e-09 38.0 0.0 1.4e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX79926.1 - 8e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX79926.1 - 0.00013 21.6 0.0 0.0087 15.7 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KXX79926.1 - 0.0004 20.2 0.0 0.0007 19.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.1 KXX79926.1 - 0.0059 17.1 0.1 0.93 10.1 0.1 2.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX79926.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KXX79926.1 - 0.022 14.6 0.0 0.052 13.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 KXX79927.1 - 1.7e-26 93.0 0.0 2.2e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX79927.1 - 5.9e-16 58.9 0.0 8.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX79927.1 - 3.4e-08 33.3 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX79927.1 - 0.00023 20.1 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KXX79927.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX79927.1 - 0.032 14.0 0.2 0.032 14.0 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_S25 PF03297.10 KXX79928.1 - 9.7e-40 134.8 5.8 1.1e-39 134.7 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 KXX79928.1 - 0.0015 17.7 0.2 0.0025 17.0 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 KXX79928.1 - 0.0028 16.9 0.2 0.0044 16.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 KXX79928.1 - 0.0055 16.2 0.1 0.0077 15.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 KXX79928.1 - 0.011 15.3 0.1 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 KXX79928.1 - 0.014 15.5 0.1 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 KXX79928.1 - 0.043 13.5 0.2 0.061 13.0 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 KXX79928.1 - 0.059 13.0 0.1 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_27 PF13463.1 KXX79928.1 - 0.073 13.4 0.1 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain FeoC PF09012.5 KXX79928.1 - 0.1 12.3 0.4 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_IclR PF09339.5 KXX79928.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_S7 PF00177.16 KXX79929.1 - 3e-41 140.4 1.0 3.6e-41 140.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e p450 PF00067.17 KXX79931.1 - 8.6e-31 106.9 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tannase PF07519.6 KXX79932.1 - 1e-90 304.7 0.0 1.2e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KXX79932.1 - 6.7e-06 26.1 0.4 4.1e-05 23.5 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX79932.1 - 0.00013 21.7 1.2 0.0051 16.5 0.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX79932.1 - 0.00021 20.5 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KXX79932.1 - 0.004 16.7 0.9 0.011 15.2 0.0 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Zn_clus PF00172.13 KXX79933.1 - 8.8e-06 25.5 3.5 1.6e-05 24.7 2.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Stb3 PF10330.4 KXX79934.1 - 1.3e-37 127.3 0.0 2e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein HET PF06985.6 KXX79935.1 - 2.1e-29 102.4 0.0 3.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Topoisom_bac PF01131.15 KXX79936.1 - 1.8e-93 313.5 0.0 3.7e-88 296.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KXX79936.1 - 1.8e-19 69.5 0.0 3.6e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EF-hand_4 PF12763.2 KXX79937.1 - 4.3e-34 116.3 0.0 1.7e-13 50.2 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KXX79937.1 - 5.9e-12 45.5 0.1 9.6e-07 28.8 0.2 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 KXX79937.1 - 1e-08 33.8 0.5 0.24 10.7 0.3 4.9 5 0 0 5 5 4 2 EF hand EF-hand_6 PF13405.1 KXX79937.1 - 1.5e-06 27.5 1.1 0.12 12.3 0.3 5.2 5 0 0 5 5 5 1 EF-hand domain Macoilin PF09726.4 KXX79937.1 - 0.00014 20.2 13.0 0.00014 20.2 9.0 2.6 3 0 0 3 3 1 1 Transmembrane protein UBA PF00627.26 KXX79937.1 - 0.00019 21.1 0.0 0.00057 19.6 0.0 1.8 2 0 0 2 2 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 KXX79937.1 - 0.0019 17.7 0.0 0.34 10.5 0.1 3.7 3 1 1 4 4 4 1 EF-hand domain pair WEMBL PF05701.6 KXX79937.1 - 0.0062 15.0 24.9 0.01 14.3 17.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 KXX79937.1 - 0.008 16.0 30.9 0.02 14.7 7.6 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 KXX79937.1 - 0.016 12.9 24.8 0.024 12.3 17.2 1.1 1 0 0 1 1 1 0 Myosin tail DUF3584 PF12128.3 KXX79937.1 - 0.08 10.2 27.7 0.11 9.7 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 KXX79937.1 - 0.089 12.6 35.8 0.19 11.5 6.9 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 KXX79937.1 - 0.1 11.8 31.7 0.47 9.6 14.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 KXX79937.1 - 0.11 12.5 35.2 0.81 9.7 8.8 3.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KXX79937.1 - 0.12 11.9 30.6 0.2 11.2 10.5 2.3 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 KXX79937.1 - 0.13 10.7 23.1 0.21 10.0 16.0 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KXX79937.1 - 0.23 10.6 11.2 0.3 10.2 2.9 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KXX79937.1 - 0.25 11.1 14.4 0.016 15.0 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 KXX79937.1 - 0.25 11.0 36.0 0.67 9.6 5.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 KXX79937.1 - 0.35 9.0 23.0 0.18 9.9 14.3 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 KXX79937.1 - 0.38 9.3 29.8 0.96 8.0 5.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CALCOCO1 PF07888.6 KXX79937.1 - 0.73 8.0 18.7 1.2 7.3 12.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 KXX79937.1 - 0.75 9.5 31.9 3.1 7.5 14.6 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 KXX79937.1 - 0.85 7.7 22.7 1.3 7.1 15.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMF_TATA_bd PF12325.3 KXX79937.1 - 0.9 9.2 26.6 0.45 10.2 2.3 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 KXX79937.1 - 1.2 8.5 29.9 0.61 9.5 10.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein FlxA PF14282.1 KXX79937.1 - 1.2 9.0 36.8 0.14 12.1 7.1 3.2 1 1 2 3 3 3 0 FlxA-like protein FlaC_arch PF05377.6 KXX79937.1 - 1.5 8.7 13.6 6.4 6.7 0.2 4.2 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 KXX79937.1 - 2 8.2 14.2 0.078 12.8 2.2 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 KXX79937.1 - 2.3 7.1 32.1 0.64 9.0 14.4 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4047 PF13256.1 KXX79937.1 - 2.7 7.9 11.7 0.59 10.1 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Rab5-bind PF09311.6 KXX79937.1 - 2.9 7.7 32.0 4.5 7.1 12.7 2.6 1 1 1 2 2 2 0 Rabaptin-like protein Cep57_MT_bd PF06657.8 KXX79937.1 - 3 7.8 13.7 2.3 8.2 2.4 3.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF724 PF05266.9 KXX79937.1 - 3.2 7.3 21.4 5.7 6.5 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mnd1 PF03962.10 KXX79937.1 - 4.3 6.9 29.7 3.1 7.4 6.9 2.5 1 1 1 2 2 2 0 Mnd1 family DUF812 PF05667.6 KXX79937.1 - 4.4 5.6 28.6 0.028 12.9 13.7 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF812) Atg14 PF10186.4 KXX79937.1 - 5.5 5.8 30.7 1.7 7.4 8.7 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4239 PF14023.1 KXX79937.1 - 7.6 5.8 5.5 13 5.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TMF_DNA_bd PF12329.3 KXX79937.1 - 9.9 6.0 33.6 0.56 10.0 1.8 3.6 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-CSL PF05207.8 KXX79938.1 - 8.1e-25 86.0 2.6 1e-24 85.7 1.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KXX79938.1 - 0.11 12.5 0.9 0.19 11.6 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain APG6 PF04111.7 KXX79940.1 - 0.00018 20.6 9.8 0.00024 20.2 6.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Herpes_UL14 PF03580.9 KXX79940.1 - 0.0021 17.8 4.1 0.0021 17.8 2.8 2.0 1 1 1 2 2 2 1 Herpesvirus UL14-like protein Bacillus_HBL PF05791.6 KXX79940.1 - 0.0062 15.9 5.8 0.08 12.2 3.7 2.2 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) IFT57 PF10498.4 KXX79940.1 - 0.029 13.0 7.2 0.043 12.5 5.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3584 PF12128.3 KXX79940.1 - 0.031 11.6 11.4 0.036 11.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.9 KXX79940.1 - 0.036 14.0 11.3 0.054 13.4 7.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.8 KXX79940.1 - 0.045 13.4 1.8 0.062 13.0 1.3 1.3 1 0 0 1 1 1 0 Aphid transmission protein DUF2368 PF10166.4 KXX79940.1 - 0.051 13.1 2.8 0.11 12.0 2.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) LMBR1 PF04791.11 KXX79940.1 - 0.093 11.3 4.7 0.11 11.1 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3983 PF13137.1 KXX79940.1 - 0.095 12.3 1.0 0.24 11.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) DUF342 PF03961.8 KXX79940.1 - 0.14 10.5 5.8 0.17 10.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 KXX79940.1 - 0.18 10.9 6.9 0.24 10.5 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4618 PF15397.1 KXX79940.1 - 0.35 10.1 11.7 0.66 9.2 8.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) YABBY PF04690.8 KXX79940.1 - 0.36 11.0 2.4 0.58 10.3 1.6 1.3 1 0 0 1 1 1 0 YABBY protein AAA_23 PF13476.1 KXX79940.1 - 0.56 10.4 8.1 0.78 10.0 5.6 1.3 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.1 KXX79940.1 - 0.72 9.6 7.2 1.1 9.1 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 KXX79940.1 - 0.89 7.3 7.0 1 7.1 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 KXX79940.1 - 1.1 8.7 9.4 2.2 7.8 6.5 1.5 1 0 0 1 1 1 0 GrpE DUF2422 PF10337.4 KXX79940.1 - 1.3 7.7 5.4 1.6 7.4 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4164 PF13747.1 KXX79940.1 - 1.5 9.0 15.8 51 4.0 10.6 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Cupredoxin_1 PF13473.1 KXX79941.1 - 0.067 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Cyt-b5 PF00173.23 KXX79942.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1129 PF06570.6 KXX79943.1 - 0.063 12.5 0.2 0.063 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Otopetrin PF03189.8 KXX79943.1 - 3.2 6.6 6.7 6.2 5.7 2.1 2.2 2 0 0 2 2 2 0 Otopetrin DUF2668 PF10873.3 KXX79944.1 - 0.036 14.2 2.1 0.038 14.1 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) Phostensin PF13914.1 KXX79944.1 - 0.078 13.0 6.4 0.16 12.0 4.4 1.5 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region DUF2613 PF11021.3 KXX79944.1 - 1.3 8.7 8.7 1.6 8.5 5.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) SSP160 PF06933.6 KXX79944.1 - 6.4 4.6 12.9 8 4.3 8.4 1.3 1 1 0 1 1 1 0 Special lobe-specific silk protein SSP160 HET PF06985.6 KXX79945.1 - 2.5e-16 60.0 0.0 6.8e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr5 PF14420.1 KXX79946.1 - 1.6e-15 56.7 0.8 3.1e-15 55.8 0.6 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KXX79946.1 - 0.092 12.6 0.2 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MIP-T3 PF10243.4 KXX79947.1 - 9.2 4.6 26.4 13 4.1 18.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Clat_adaptor_s PF01217.15 KXX79948.1 - 5.1e-43 146.1 0.0 7.3e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SMC_hinge PF06470.8 KXX79948.1 - 0.085 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Frataxin_Cyay PF01491.11 KXX79949.1 - 3.2e-35 120.2 0.0 4.3e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain GMC_oxred_N PF00732.14 KXX79950.1 - 1.8e-57 194.7 0.0 2.7e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX79950.1 - 5.2e-29 101.3 0.0 8.7e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF3486 PF11985.3 KXX79951.1 - 0.093 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) tRNA-synt_1 PF00133.17 KXX79952.1 - 1.6e-38 132.1 0.0 2.8e-28 98.2 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KXX79952.1 - 4.8e-19 68.2 0.0 4.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KXX79952.1 - 2.4e-14 53.3 0.9 4.3e-14 52.5 0.4 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KXX79952.1 - 2.3e-08 33.5 0.0 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain BESS PF02944.15 KXX79953.1 - 0.0061 16.0 0.7 0.014 14.9 0.5 1.6 1 0 0 1 1 1 1 BESS motif BTB_2 PF02214.17 KXX79954.1 - 7.6e-07 29.2 0.2 0.0023 18.1 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Tubulin PF00091.20 KXX79955.1 - 1.4e-69 234.2 0.0 2e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KXX79955.1 - 4.8e-49 165.5 0.1 8.2e-49 164.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KXX79955.1 - 0.0011 18.5 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KXX79955.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) tRNA_U5-meth_tr PF05958.6 KXX79956.1 - 3.3e-07 29.3 0.0 1.4e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KXX79956.1 - 3.3e-06 26.7 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KXX79956.1 - 1.3e-05 24.8 0.3 3e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 KXX79956.1 - 0.0014 19.1 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX79956.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KXX79956.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glycos_transf_1 PF00534.15 KXX79957.1 - 1.2e-20 73.5 0.0 1.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KXX79957.1 - 2.5e-10 40.6 0.0 4.8e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KXX79957.1 - 0.0083 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.15 KXX79958.1 - 2.5e-10 40.3 0.0 1.2e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein Ferric_reduct PF01794.14 KXX79959.1 - 0.00016 21.7 2.0 0.00031 20.8 1.4 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Trp_DMAT PF11991.3 KXX79960.1 - 7.5e-85 285.2 0.0 8.8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Acetyltransf_1 PF00583.19 KXX79961.1 - 0.0058 16.6 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CysG_dimeriser PF10414.4 KXX79961.1 - 0.023 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Acetyltransf_7 PF13508.1 KXX79961.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.17 KXX79962.1 - 0.00051 19.1 7.8 0.00071 18.6 5.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Gly-zipper_Omp PF13488.1 KXX79962.1 - 0.00079 19.0 6.3 0.0028 17.2 0.1 2.4 2 0 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.10 KXX79962.1 - 0.0022 17.6 10.5 0.01 15.4 1.2 2.5 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KXX79962.1 - 0.16 11.6 7.2 0.29 10.8 0.3 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF2217 PF10265.4 KXX79962.1 - 1.5 7.5 3.3 17 4.0 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) NICE-3 PF07406.6 KXX79963.1 - 0.085 12.3 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 NICE-3 protein DUF2463 PF09591.5 KXX79963.1 - 0.57 9.7 6.1 0.89 9.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) DUF2427 PF10348.4 KXX79963.1 - 0.87 9.1 4.2 1.5 8.4 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Hydrophobin PF01185.13 KXX79965.1 - 7.2e-05 23.1 6.2 7.2e-05 23.1 4.3 2.1 1 1 1 2 2 2 1 Fungal hydrophobin RINGv PF12906.2 KXX79966.1 - 3.8e-09 36.4 4.1 7.6e-09 35.4 0.6 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KXX79966.1 - 0.013 15.3 4.9 0.013 15.3 0.9 2.1 2 0 0 2 2 2 0 Ring finger domain Wzy_C PF04932.10 KXX79966.1 - 0.26 11.0 2.7 1.7 8.4 0.0 2.0 1 1 1 2 2 2 0 O-Antigen ligase PHD PF00628.24 KXX79966.1 - 0.76 9.5 5.0 0.21 11.2 1.2 1.7 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.7 KXX79967.1 - 1.7e-77 260.1 0.0 2.1e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KXX79967.1 - 1.6e-05 24.3 0.0 0.037 13.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Citrate_synt PF00285.16 KXX79968.1 - 5.4e-19 68.1 0.0 2.2e-16 59.5 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KXX79968.1 - 1.4e-18 67.1 0.0 4e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 KXX79968.1 - 6.2e-16 58.3 0.1 1.5e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KXX79968.1 - 8e-06 25.5 0.0 0.00022 20.8 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 KXX79969.1 - 3e-07 30.0 0.0 1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KXX79969.1 - 0.015 15.0 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Arginosuc_synth PF00764.14 KXX79970.1 - 3.9e-136 454.1 0.0 1.9e-88 297.1 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase Asn_synthase PF00733.16 KXX79970.1 - 0.00041 19.9 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KXX79970.1 - 0.045 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Mito_carr PF00153.22 KXX79971.1 - 2.7e-51 171.2 0.7 3.9e-18 64.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Calcipressin PF04847.7 KXX79972.1 - 2.5e-55 186.9 0.2 2.5e-55 186.9 0.1 2.1 2 1 0 2 2 2 1 Calcipressin Activator_LAG-3 PF11498.3 KXX79972.1 - 0.49 9.0 16.9 0.74 8.5 11.7 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK5_activator PF03261.10 KXX79972.1 - 0.95 8.7 4.4 1.3 8.2 3.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 KXX79972.1 - 1.4 8.5 5.8 2.1 8.0 4.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex16 PF08610.5 KXX79972.1 - 1.9 7.3 4.9 2.5 7.0 3.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FCP1_C PF09309.5 KXX79972.1 - 3.5 6.8 10.6 7.1 5.8 7.3 1.5 1 0 0 1 1 1 0 FCP1, C-terminal tRNA-synt_2d PF01409.15 KXX79973.1 - 2.3e-47 161.2 0.4 3e-24 85.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KXX79973.1 - 9.9e-26 89.7 0.0 2.1e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain WD40 PF00400.27 KXX79974.1 - 4e-16 58.1 11.4 8.6e-05 22.2 0.0 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat LVIVD PF08309.6 KXX79974.1 - 0.96 8.4 5.0 7.4 5.6 1.0 2.5 2 0 0 2 2 2 0 LVIVD repeat Neugrin PF06413.6 KXX79975.1 - 4.2e-13 49.6 1.3 4.2e-13 49.6 0.9 2.5 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KXX79975.1 - 0.00025 21.0 7.6 0.00025 21.0 5.3 3.3 2 2 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Glyco_hydro_72 PF03198.9 KXX79976.1 - 7.2e-116 386.5 0.0 8.7e-116 386.2 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KXX79976.1 - 0.0036 16.5 0.0 0.04 13.1 0.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) WLM PF08325.5 KXX79977.1 - 2.2e-48 164.5 0.0 3.7e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KXX79977.1 - 0.0002 21.2 1.9 0.00037 20.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 KXX79977.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Proteasome PF00227.21 KXX79978.1 - 3.7e-57 192.6 0.0 3.3e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KXX79978.1 - 2e-11 42.9 0.3 4.3e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 KXX79978.1 - 0.26 9.7 1.8 9.9 4.5 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pyridoxal_deC PF00282.14 KXX79979.1 - 6.4e-16 57.7 0.0 9.1e-16 57.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KXX79979.1 - 0.0022 16.8 0.0 0.0044 15.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KXX79979.1 - 0.075 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribonuclease_3 PF00636.21 KXX79980.1 - 2.5e-35 121.3 0.0 1.6e-16 60.7 0.0 2.7 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX79980.1 - 7.3e-19 67.9 0.0 1.5e-07 31.3 0.0 4.0 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KXX79980.1 - 9e-18 63.8 0.1 4.6e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KXX79980.1 - 2.8e-16 59.1 0.0 1.3e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX79980.1 - 8e-16 57.9 0.1 4e-14 52.4 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KXX79980.1 - 1.8e-07 31.1 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 KXX79980.1 - 0.00027 21.4 0.1 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif RCC1_2 PF13540.1 KXX79981.1 - 9.1e-18 63.3 14.0 2.5e-08 33.3 0.4 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KXX79981.1 - 2.8e-14 53.0 2.1 0.0017 18.5 0.0 4.5 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat CENP-Q PF13094.1 KXX79983.1 - 2.3e-33 115.4 2.0 2.6e-33 115.2 0.0 2.1 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_L30 PF00327.15 KXX79984.1 - 8.6e-16 57.2 0.0 1.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 KXX79985.1 - 3.1e-56 189.3 0.1 4.5e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KXX79985.1 - 1e-06 28.2 0.6 2.1e-06 27.3 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KXX79985.1 - 0.0042 16.7 0.4 0.011 15.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 KXX79987.1 - 1.4e-26 91.9 1.9 2.6e-26 91.0 1.3 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Rabaptin PF03528.10 KXX79987.1 - 0.0033 17.3 0.3 0.0033 17.3 0.2 2.0 1 1 1 2 2 2 1 Rabaptin DUF1351 PF07083.6 KXX79987.1 - 0.038 13.5 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) GIT1_C PF12205.3 KXX79987.1 - 0.13 12.0 0.3 0.86 9.4 0.0 2.0 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term IncA PF04156.9 KXX79987.1 - 1.2 8.6 8.1 0.24 10.9 1.6 1.9 1 1 1 2 2 2 0 IncA protein Syntaxin_2 PF14523.1 KXX79988.1 - 2.2e-27 95.0 1.2 2.2e-27 95.0 0.8 3.0 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KXX79988.1 - 3.5e-18 65.0 3.0 3.5e-18 65.0 2.1 2.4 2 0 0 2 2 2 1 SNARE domain EspB PF05802.6 KXX79988.1 - 0.017 14.0 0.5 0.017 14.0 0.4 1.8 2 0 0 2 2 2 0 Enterobacterial EspB protein VCX_VCY PF15231.1 KXX79988.1 - 0.022 15.1 0.2 0.035 14.4 0.2 1.4 1 0 0 1 1 1 0 Variable charge X/Y family Synaptobrevin PF00957.16 KXX79988.1 - 0.045 13.3 0.8 0.18 11.4 0.1 2.4 2 1 1 3 3 3 0 Synaptobrevin Pex19 PF04614.7 KXX79988.1 - 0.055 13.0 5.3 0.023 14.3 2.0 1.5 2 0 0 2 2 2 0 Pex19 protein family ISG65-75 PF11727.3 KXX79988.1 - 0.13 11.3 5.2 0.51 9.3 0.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF883 PF05957.8 KXX79988.1 - 0.17 12.2 10.1 4 7.9 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 KXX79988.1 - 0.29 10.9 4.4 6.1 6.6 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 KXX79988.1 - 0.66 9.4 9.7 0.28 10.7 1.8 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF651 PF04895.7 KXX79988.1 - 0.83 9.3 3.9 0.85 9.2 0.1 2.5 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF651) Prominin PF05478.6 KXX79988.1 - 0.86 7.0 5.2 1.4 6.3 3.6 1.3 1 1 0 1 1 1 0 Prominin GrpE PF01025.14 KXX79989.1 - 4.1e-52 176.0 7.5 5.2e-52 175.7 5.2 1.1 1 0 0 1 1 1 1 GrpE BCDHK_Adom3 PF10436.4 KXX79989.1 - 0.012 15.1 0.3 0.018 14.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Peptidase_S49 PF01343.13 KXX79989.1 - 0.28 10.9 2.8 0.31 10.8 1.3 1.5 1 1 0 1 1 1 0 Peptidase family S49 IncA PF04156.9 KXX79989.1 - 1.4 8.4 4.7 2.3 7.7 3.3 1.3 1 0 0 1 1 1 0 IncA protein RNA_pol_A_bac PF01000.21 KXX79990.1 - 1.4e-31 108.9 0.0 2.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KXX79990.1 - 1e-14 53.3 0.0 1.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prominin PF05478.6 KXX79991.1 - 0.0068 13.9 13.6 0.0088 13.6 9.4 1.0 1 0 0 1 1 1 1 Prominin TBPIP PF07106.8 KXX79991.1 - 0.014 14.9 7.5 0.068 12.7 5.3 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 KXX79991.1 - 0.018 14.2 6.4 0.034 13.3 4.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Herpes_U30 PF04523.8 KXX79991.1 - 0.12 9.8 12.7 0.15 9.4 8.8 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 IFT57 PF10498.4 KXX79991.1 - 0.15 10.7 8.6 0.24 10.0 5.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.6 KXX79991.1 - 0.67 9.3 11.0 0.42 9.9 3.7 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF972 PF06156.8 KXX79991.1 - 0.93 9.8 9.6 0.41 11.0 4.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rifin_STEVOR PF02009.11 KXX79991.1 - 1.1 8.8 18.0 0.069 12.7 2.4 2.2 1 1 1 2 2 2 0 Rifin/stevor family AAA_13 PF13166.1 KXX79991.1 - 1.7 6.9 12.5 2.4 6.4 8.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KXX79991.1 - 1.9 5.7 30.2 2.6 5.2 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 KXX79991.1 - 3.7 7.3 9.5 0.59 9.9 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Birna_RdRp PF04197.7 KXX79991.1 - 4.3 5.2 13.2 5.7 4.8 9.2 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) TMF_DNA_bd PF12329.3 KXX79991.1 - 4.4 7.1 13.6 10 6.0 8.9 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0118 PF01594.11 KXX79991.1 - 6.4 5.6 5.3 7.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF20 TMPIT PF07851.8 KXX79991.1 - 8.1 5.4 15.6 0.94 8.4 6.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.5 KXX79991.1 - 8.9 6.4 15.1 1.9 8.5 6.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ER_lumen_recept PF00810.13 KXX79992.1 - 5.9e-55 185.7 8.7 1e-54 185.0 6.0 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KXX79992.1 - 0.065 12.7 0.2 0.065 12.7 0.1 4.1 4 1 2 6 6 6 0 PQ loop repeat Rgp1 PF08737.5 KXX79993.1 - 3e-119 398.8 0.0 3.9e-119 398.4 0.0 1.1 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 KXX79993.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LicD PF04991.8 KXX79994.1 - 8.2e-08 32.6 0.0 1.9e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 LicD family RFC1 PF08519.7 KXX79995.1 - 4.1e-59 198.7 0.0 7.9e-59 197.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KXX79995.1 - 4.4e-12 45.9 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KXX79995.1 - 6.3e-09 36.1 0.0 2e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KXX79995.1 - 3.5e-06 25.9 0.0 7e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 KXX79995.1 - 3.5e-05 23.4 0.0 7.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 KXX79995.1 - 5.2e-05 24.0 4.6 9.1e-05 23.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KXX79995.1 - 0.00075 19.6 0.0 0.014 15.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX79995.1 - 0.0014 18.9 0.1 0.0014 18.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KXX79995.1 - 0.0015 18.2 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KXX79995.1 - 0.0037 17.1 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX79995.1 - 0.0046 16.9 0.0 0.064 13.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KXX79995.1 - 0.017 15.1 1.5 0.041 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KXX79995.1 - 0.033 14.0 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KXX79995.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.7 KXX79995.1 - 0.095 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF1682 PF07946.9 KXX79995.1 - 0.8 8.4 14.1 0.013 14.3 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Rep_fac_C PF08542.6 KXX79997.1 - 8.9e-23 80.0 0.0 3.3e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KXX79997.1 - 8.2e-12 45.0 0.0 1.6e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KXX79997.1 - 7.9e-07 29.3 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX79997.1 - 3.3e-06 27.2 0.4 6.8e-05 23.0 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KXX79997.1 - 3.3e-05 23.9 1.2 0.0096 15.9 0.6 3.1 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KXX79997.1 - 0.0055 16.7 0.3 0.22 11.5 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 KXX79997.1 - 0.0092 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 KXX79997.1 - 0.0095 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KXX79997.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Arch_ATPase PF01637.13 KXX79997.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 KXX79997.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) Aconitase_B_N PF11791.3 KXX79997.1 - 0.029 14.1 0.1 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Aconitate B N-terminal domain T4SS-DNA_transf PF02534.9 KXX79997.1 - 0.041 12.4 0.1 0.14 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 KXX79997.1 - 0.049 12.3 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KXX79997.1 - 0.073 12.5 0.1 2.1 7.7 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain SNF2_N PF00176.18 KXX79997.1 - 0.092 11.5 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_24 PF13479.1 KXX79997.1 - 0.42 10.1 1.9 1.6 8.2 1.3 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 KXX79998.1 - 1.4e-29 102.5 0.3 1.9e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 KXX79998.1 - 0.051 13.3 0.1 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Ndc1_Nup PF09531.5 KXX79999.1 - 2.6e-156 521.5 0.0 2.9e-156 521.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Methyltransf_12 PF08242.7 KXX80000.1 - 1.6e-11 44.5 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80000.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80000.1 - 6.1e-10 39.6 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80000.1 - 7.5e-09 35.3 0.0 9.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80000.1 - 2.7e-08 34.0 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX80000.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX80000.1 - 2.3e-07 30.1 0.0 3.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX80000.1 - 4.1e-07 30.0 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX80000.1 - 2.9e-05 23.5 0.0 4.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 KXX80000.1 - 0.0049 16.1 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KXX80000.1 - 0.0079 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF2737 PF10930.3 KXX80001.1 - 0.093 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Trypan_PARP PF05887.6 KXX80003.1 - 0.014 15.2 20.8 0.014 15.2 14.4 3.5 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Aldolase_II PF00596.16 KXX80005.1 - 7.8e-30 103.8 0.0 9.8e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SH3_1 PF00018.23 KXX80006.1 - 0.00017 20.9 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX80006.1 - 0.0032 17.0 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX80006.1 - 0.034 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Dynamin_N PF00350.18 KXX80007.1 - 1.3e-33 116.2 0.1 2.3e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX80007.1 - 4.1e-15 55.3 0.0 4.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KXX80007.1 - 6.7e-05 22.8 0.0 0.00033 20.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KXX80007.1 - 0.0008 19.2 1.1 0.0026 17.6 0.1 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 KXX80007.1 - 0.002 18.6 0.0 0.006 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KXX80007.1 - 0.018 15.0 0.0 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX80007.1 - 0.046 14.0 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Syntaxin_2 PF14523.1 KXX80007.1 - 0.081 12.9 0.8 2.1 8.4 0.0 3.3 4 0 0 4 4 4 0 Syntaxin-like protein AAA_23 PF13476.1 KXX80007.1 - 0.087 13.1 0.0 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KXX80007.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.2 KXX80008.1 - 1.3e-97 320.2 15.8 2.2e-22 79.2 0.0 7.7 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KXX80008.1 - 1.7e-83 270.5 30.1 5.7e-09 35.3 0.0 14.4 14 0 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.1 KXX80008.1 - 2.6e-60 194.2 13.2 1e-05 25.2 0.0 14.3 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 KXX80008.1 - 1.7e-59 197.1 11.9 9.4e-11 41.9 0.0 10.6 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX80008.1 - 1.1e-53 178.0 21.5 4.7e-09 36.2 0.1 12.5 4 2 9 13 13 13 11 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.3 KXX80008.1 - 0.24 11.4 2.0 0.9 9.6 0.4 2.8 2 0 0 2 2 2 0 Selenocysteine synthase N terminal MRP-L28 PF09812.4 KXX80009.1 - 0.062 13.1 3.2 2.3 8.0 0.9 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L28 Phlebovirus_NSM PF07246.6 KXX80009.1 - 0.23 10.5 4.3 0.38 9.8 3.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sipho_Gp157 PF05565.6 KXX80009.1 - 0.27 10.7 3.8 0.47 10.0 2.7 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4140 PF13600.1 KXX80009.1 - 0.43 11.0 4.1 15 6.0 1.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FA_desaturase PF00487.19 KXX80010.1 - 2 7.7 11.6 2.4 7.5 7.8 1.4 1 1 0 1 1 1 0 Fatty acid desaturase FAD_binding_3 PF01494.14 KXX80011.1 - 1.2e-14 54.1 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_C PF05199.8 KXX80012.1 - 2.5e-32 112.1 0.0 3.9e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KXX80012.1 - 1.9e-29 102.7 0.0 5.9e-25 88.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX80012.1 - 0.00067 19.6 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX80012.1 - 0.0057 16.5 0.0 0.063 13.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX80012.1 - 0.0061 15.4 0.3 0.011 14.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX80012.1 - 0.047 12.5 1.5 0.92 8.3 0.6 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KXX80012.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KXX80012.1 - 0.056 13.4 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFA PF04828.9 KXX80013.1 - 2.4e-16 59.4 1.8 3.4e-09 36.5 1.0 3.2 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme Di19_C PF14571.1 KXX80013.1 - 0.065 13.5 0.1 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal Herpes_Helicase PF02689.9 KXX80014.1 - 0.00018 19.4 0.0 0.00025 18.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KXX80014.1 - 0.00079 19.5 0.2 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Abhydrolase_3 PF07859.8 KXX80015.1 - 9.1e-30 103.8 0.0 1.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX80015.1 - 5e-06 26.3 0.0 7.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KXX80015.1 - 7.9e-06 24.8 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KXX80015.1 - 0.00075 19.4 1.0 0.0012 18.7 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX80015.1 - 0.0054 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KXX80015.1 - 0.0084 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KXX80015.1 - 0.017 13.6 0.1 0.033 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AOX PF01786.12 KXX80016.1 - 2.2e-79 265.6 0.0 2.7e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase ADH_zinc_N_2 PF13602.1 KXX80019.1 - 2.3e-21 76.9 0.1 3.6e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX80019.1 - 3.7e-15 55.6 0.2 6.1e-15 54.9 0.1 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX80019.1 - 0.08 12.7 0.9 4.2 7.1 0.1 3.1 2 2 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain PH_8 PF15409.1 KXX80020.1 - 0.033 14.2 0.8 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1232 PF06803.7 KXX80020.1 - 0.32 10.4 6.1 0.09 12.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) Esterase_phd PF10503.4 KXX80021.1 - 1.3e-22 80.1 0.4 1.8e-22 79.6 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KXX80021.1 - 2e-09 37.0 0.9 3.2e-09 36.3 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KXX80021.1 - 5.2e-07 29.5 0.1 7.2e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KXX80021.1 - 0.00021 20.8 0.8 0.00032 20.2 0.5 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KXX80021.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX80021.1 - 0.0083 15.7 0.2 0.016 14.7 0.0 1.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KXX80021.1 - 0.016 14.8 0.1 0.026 14.0 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KXX80021.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KXX80021.1 - 0.041 13.5 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Eapp_C PF10238.4 KXX80022.1 - 0.0021 17.9 2.2 0.49 10.2 0.0 2.2 2 0 0 2 2 2 2 E2F-associated phosphoprotein zf-C3HC4_3 PF13920.1 KXX80022.1 - 1.1 8.9 0.1 1.1 8.9 0.0 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Atrophin-1 PF03154.10 KXX80022.1 - 2.7 6.0 13.4 2.6 6.0 3.7 2.1 2 0 0 2 2 2 0 Atrophin-1 family DUF4419 PF14388.1 KXX80023.1 - 4.6e-91 305.1 0.0 9.1e-91 304.1 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) TPR_11 PF13414.1 KXX80025.1 - 7.2e-56 185.7 26.8 2.8e-16 58.9 0.9 6.7 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KXX80025.1 - 3.7e-46 152.9 33.0 2.7e-06 26.7 0.0 11.3 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80025.1 - 7.8e-40 131.5 30.6 2.6e-05 23.7 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 KXX80025.1 - 3.8e-28 97.5 11.4 8e-07 29.5 0.4 7.1 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KXX80025.1 - 1.5e-26 90.3 12.0 0.00058 19.8 0.4 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80025.1 - 2.3e-26 91.5 25.5 4.2e-06 26.6 0.0 7.3 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 KXX80025.1 - 1.8e-14 52.3 27.5 0.0082 15.8 0.1 10.6 10 1 1 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 KXX80025.1 - 5.1e-13 48.9 19.5 0.0012 18.8 0.2 5.4 3 1 3 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX80025.1 - 5.7e-13 48.5 10.7 4.3e-05 23.2 0.2 6.8 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80025.1 - 1.5e-12 47.6 22.2 0.00018 21.7 0.7 7.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80025.1 - 6.7e-12 44.9 19.4 0.043 14.4 0.2 10.1 3 3 6 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX80025.1 - 1.3e-10 40.2 25.5 0.14 12.0 0.2 9.5 9 1 1 10 10 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KXX80025.1 - 1.3e-06 27.4 5.9 0.57 9.4 0.0 6.0 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.1 KXX80025.1 - 1.8e-06 27.2 10.7 0.29 10.1 0.6 5.7 3 1 1 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.2 KXX80025.1 - 0.0037 17.0 8.1 7.3 6.4 0.0 5.7 4 3 0 4 4 4 1 Domain of Unknown Function (DUF3856) Sel1 PF08238.7 KXX80025.1 - 0.16 12.6 5.1 1.5 9.5 0.1 3.9 3 0 0 3 3 3 0 Sel1 repeat TPR_20 PF14561.1 KXX80025.1 - 0.23 11.6 9.3 8.7 6.5 0.2 5.0 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX80025.1 - 0.44 11.1 26.4 19 5.9 0.3 9.3 10 1 0 10 10 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 KXX80025.1 - 3.1 7.8 17.0 4.5 7.3 0.5 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 KXX80025.1 - 4.7 5.8 26.8 0.76 8.4 2.0 4.5 2 2 0 3 3 2 0 NMDA receptor-regulated protein 1 Syntaxin PF00804.20 KXX80026.1 - 5.4e-11 42.5 5.4 5.4e-11 42.5 3.7 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KXX80026.1 - 3.6e-07 29.7 6.4 3.6e-07 29.7 4.4 2.2 2 0 0 2 2 2 1 SNARE domain Spc7 PF08317.6 KXX80026.1 - 0.14 10.8 13.5 0.69 8.5 0.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3018 PF11455.3 KXX80026.1 - 0.23 11.4 5.9 0.23 11.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) SlyX PF04102.7 KXX80026.1 - 0.31 11.4 9.5 0.09 13.1 1.7 2.9 2 1 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.7 KXX80026.1 - 2.5 7.9 16.2 1.4 8.7 1.9 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Synaptobrevin PF00957.16 KXX80026.1 - 2.9 7.5 8.1 0.34 10.5 1.5 2.3 2 1 1 3 3 3 0 Synaptobrevin FAA_hydrolase_N PF09298.6 KXX80026.1 - 2.9 7.9 7.2 1.4 8.9 0.6 2.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal Syntaxin_2 PF14523.1 KXX80026.1 - 8.6 6.4 18.1 0.3 11.1 5.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Brix PF04427.13 KXX80027.1 - 6.7e-45 153.1 0.5 8.7e-45 152.7 0.4 1.1 1 0 0 1 1 1 1 Brix domain AAA PF00004.24 KXX80028.1 - 1.1e-15 57.9 0.0 2.4e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KXX80028.1 - 0.0002 21.0 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KXX80028.1 - 0.0013 18.8 0.7 0.018 15.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX80028.1 - 0.0031 18.3 0.5 0.02 15.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX80028.1 - 0.0032 17.1 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX80028.1 - 0.019 14.9 0.1 0.081 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KXX80028.1 - 0.039 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain PKD_channel PF08016.7 KXX80029.1 - 1.8e-05 23.3 16.5 0.00087 17.8 11.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 KXX80029.1 - 0.013 14.7 19.4 1.5 8.0 13.5 2.3 1 1 0 1 1 1 0 Ion transport protein DUF843 PF05814.6 KXX80029.1 - 1.7 8.4 6.5 0.75 9.6 0.3 2.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Asp PF00026.18 KXX80030.1 - 1.1e-11 44.5 0.2 4e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Pectate_lyase PF03211.8 KXX80030.1 - 0.051 12.9 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase Asp_protease_2 PF13650.1 KXX80030.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Aminotran_4 PF01063.14 KXX80031.1 - 7.5e-22 77.9 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV XAP5 PF04921.9 KXX80032.1 - 8.5e-81 271.0 0.0 1.5e-80 270.2 0.0 1.4 2 0 0 2 2 2 1 XAP5, circadian clock regulator Herpes_US12 PF05363.7 KXX80032.1 - 0.12 12.8 3.7 0.12 12.9 0.5 2.5 2 0 0 2 2 2 0 Herpesvirus US12 family Methyltransf_10 PF05971.7 KXX80033.1 - 6.6e-66 222.4 0.0 8.4e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KXX80033.1 - 2e-06 27.8 0.0 3.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX80033.1 - 4.8e-06 26.0 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KXX80033.1 - 1.3e-05 25.7 0.0 2.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80033.1 - 0.0005 19.6 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KXX80033.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KXX80033.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KXX80033.1 - 0.032 14.7 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80033.1 - 0.034 14.5 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KXX80033.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 KXX80033.1 - 0.051 13.1 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Reo_sigmaC PF04582.7 KXX80034.1 - 0.00019 20.7 9.6 0.0009 18.5 5.8 2.2 1 1 2 3 3 3 3 Reovirus sigma C capsid protein Spc7 PF08317.6 KXX80034.1 - 0.00083 18.1 21.7 0.00083 18.1 15.0 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein TBPIP PF07106.8 KXX80034.1 - 0.0021 17.6 15.5 0.0021 17.6 10.8 3.3 1 1 1 3 3 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KXX80034.1 - 0.0026 17.4 25.6 0.0026 17.4 17.8 3.0 1 1 1 2 2 2 1 IncA protein CENP-F_leu_zip PF10473.4 KXX80034.1 - 0.0026 17.6 15.6 0.0026 17.6 10.8 3.8 1 1 3 4 4 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KXX80034.1 - 0.0042 16.5 11.7 0.0042 16.5 8.1 3.1 1 1 1 3 3 3 2 Intermediate filament protein GAS PF13851.1 KXX80034.1 - 0.0063 15.7 17.1 0.0063 15.7 11.8 3.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KXX80034.1 - 0.0077 16.3 9.9 0.0077 16.3 6.8 2.8 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family SlyX PF04102.7 KXX80034.1 - 0.0089 16.3 19.4 0.058 13.7 6.6 4.0 1 1 2 3 3 3 2 SlyX ATG16 PF08614.6 KXX80034.1 - 0.009 15.8 10.7 0.009 15.8 7.4 2.9 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ADIP PF11559.3 KXX80034.1 - 0.012 15.5 11.2 0.012 15.5 7.8 3.4 1 1 3 4 4 3 0 Afadin- and alpha -actinin-Binding M_domain PF12938.2 KXX80034.1 - 0.035 13.9 3.6 0.062 13.1 2.5 1.4 1 0 0 1 1 1 0 M domain of GW182 Myosin_tail_1 PF01576.14 KXX80034.1 - 0.039 11.6 53.9 0.12 10.0 37.3 1.8 1 1 0 1 1 1 0 Myosin tail DUF3584 PF12128.3 KXX80034.1 - 0.052 10.8 45.3 0.072 10.4 31.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.7 KXX80034.1 - 0.57 7.9 38.4 1.8 6.2 26.6 1.7 1 1 0 1 1 1 0 HOOK protein Snapin_Pallidin PF14712.1 KXX80034.1 - 1 9.7 13.9 0.41 10.9 1.4 3.0 1 1 1 2 2 2 0 Snapin/Pallidin NBP1 PF08537.5 KXX80034.1 - 1.1 8.3 17.3 1.8 7.6 12.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Bacillus_HBL PF05791.6 KXX80034.1 - 1.5 8.1 16.1 2.2 7.6 8.6 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Atg14 PF10186.4 KXX80034.1 - 2 7.3 27.3 0.29 10.0 10.7 2.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 KXX80034.1 - 2.1 8.1 17.3 4.2 7.1 0.9 4.3 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin PF00261.15 KXX80034.1 - 2.8 6.9 58.0 3.1 6.8 39.3 1.9 1 1 0 1 1 1 0 Tropomyosin Prefoldin PF02996.12 KXX80034.1 - 3.1 7.4 29.0 0.13 11.9 2.5 4.9 2 2 2 5 5 5 0 Prefoldin subunit NPV_P10 PF05531.7 KXX80034.1 - 3.2 8.0 10.0 3.7e+02 1.4 6.3 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 KXX80034.1 - 3.4 7.5 16.3 1 9.2 3.0 3.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HAP1_N PF04849.8 KXX80034.1 - 3.5 6.4 39.9 58 2.4 27.7 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region RTBV_P46 PF06216.6 KXX80034.1 - 4.2 6.0 6.9 3.1 6.5 1.9 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF1664 PF07889.7 KXX80034.1 - 4.4 7.1 13.0 1.3 8.8 4.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tnp_P_element PF12017.3 KXX80034.1 - 7.2 5.7 7.6 5.8 6.0 1.6 2.4 1 1 1 2 2 2 0 Transposase protein DUF842 PF05811.8 KXX80035.1 - 0.015 14.7 0.7 0.022 14.1 0.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) MtrG PF04210.8 KXX80035.1 - 0.043 13.4 0.6 1.9 8.2 0.0 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cortex-I_coil PF09304.5 KXX80035.1 - 0.088 12.8 0.9 0.12 12.4 0.6 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil PP2C_C PF07830.8 KXX80035.1 - 0.096 12.8 0.8 0.25 11.4 0.1 1.8 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain FliT PF05400.8 KXX80035.1 - 0.18 12.2 3.1 0.25 11.7 0.2 2.4 1 1 1 2 2 2 0 Flagellar protein FliT Peptidase_M20 PF01546.23 KXX80036.1 - 6.8e-26 90.9 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KXX80036.1 - 2.8e-12 46.3 0.0 5.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KXX80036.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Axin_b-cat_bind PF08833.5 KXX80039.1 - 0.017 14.8 7.9 0.25 11.0 1.7 2.6 1 1 2 3 3 3 0 Axin beta-catenin binding domain Lipoprotein_5 PF01298.13 KXX80039.1 - 0.15 10.9 3.6 0.17 10.8 2.5 1.1 1 0 0 1 1 1 0 Transferrin binding protein-like solute binding protein Imm38 PF15599.1 KXX80040.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 38 Clr5 PF14420.1 KXX80041.1 - 3.3e-20 71.7 0.4 7.9e-20 70.5 0.3 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KXX80041.1 - 0.073 13.0 0.1 0.76 9.7 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.21 KXX80042.1 - 6.7e-92 308.6 1.6 9.3e-92 308.1 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AAA_9 PF12781.2 KXX80043.1 - 0.026 13.3 1.2 0.041 12.7 0.8 1.3 1 0 0 1 1 1 0 ATP-binding dynein motor region D5 HrpF PF06266.7 KXX80043.1 - 0.034 14.2 1.2 0.034 14.2 0.8 2.2 2 0 0 2 2 2 0 HrpF protein Rab5-bind PF09311.6 KXX80043.1 - 0.12 12.2 33.7 0.44 10.4 22.3 1.9 1 1 0 1 1 1 0 Rabaptin-like protein PgaD PF13994.1 KXX80043.1 - 1.6 8.1 5.9 1.3 8.4 0.4 2.4 1 1 0 2 2 2 0 PgaD-like protein Macoilin PF09726.4 KXX80043.1 - 3.1 5.9 23.5 3.4 5.8 16.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 KXX80043.1 - 7.1 3.8 35.2 12 3.0 23.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NMO PF03060.10 KXX80045.1 - 1.9e-33 116.0 10.0 1.4e-25 90.1 3.9 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KXX80045.1 - 5e-10 38.7 0.0 0.0019 17.1 2.3 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX80045.1 - 2.5e-05 23.2 4.9 3.3e-05 22.9 3.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.20 KXX80046.1 - 1.1e-33 116.4 2.4 1.7e-33 115.9 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX80046.1 - 3.6e-16 59.6 0.6 4.3e-16 59.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX80046.1 - 1.6e-10 40.9 0.7 3.2e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX80046.1 - 1.7e-05 24.4 0.3 2.3e-05 23.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KXX80046.1 - 0.00071 19.2 0.7 0.0011 18.6 0.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KXX80046.1 - 0.0019 17.1 0.2 0.0027 16.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 KXX80046.1 - 0.0042 16.7 0.3 0.0068 16.0 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 KXX80046.1 - 0.0051 15.5 0.1 0.0069 15.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KXX80046.1 - 0.01 14.7 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KXX80046.1 - 0.014 14.6 0.5 0.025 13.8 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 KXX80046.1 - 0.014 15.7 0.5 0.029 14.7 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KXX80046.1 - 0.016 15.1 0.2 0.026 14.5 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KXX80046.1 - 0.03 13.4 0.2 0.062 12.4 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KXX80046.1 - 0.032 13.3 0.1 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KXX80046.1 - 0.042 13.6 1.5 0.17 11.7 0.9 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Enoyl_reductase PF12241.3 KXX80046.1 - 0.078 11.9 0.2 0.61 9.0 0.0 2.0 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region NAD_binding_10 PF13460.1 KXX80046.1 - 0.084 12.8 0.5 0.19 11.6 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding tRNA-synt_1e PF01406.14 KXX80047.1 - 4.8e-111 370.6 0.2 1.1e-110 369.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KXX80047.1 - 0.00031 19.5 0.2 0.55 8.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KXX80047.1 - 0.0006 20.0 0.9 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 DALR domain AMP-binding PF00501.23 KXX80048.1 - 4.7e-86 288.7 0.0 5.5e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX80048.1 - 2.5e-18 66.8 0.1 8e-18 65.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.10 KXX80051.1 - 2.1e-13 50.5 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_S64 PF08192.6 KXX80052.1 - 0.037 12.3 0.0 0.063 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_61 PF03443.9 KXX80054.1 - 9.3e-10 38.6 0.0 1.1e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.6 KXX80055.1 - 6.5e-29 100.8 0.0 2.1e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ricin_B_lectin PF00652.17 KXX80056.1 - 1.3e-11 44.5 1.4 1.4e-08 34.7 0.4 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KXX80056.1 - 2.3e-09 37.5 3.0 1.2e-05 25.6 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF884 PF05959.6 KXX80056.1 - 0.03 13.6 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF884) SnoaL PF07366.7 KXX80057.1 - 4.8e-14 52.0 0.2 3.3e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KXX80057.1 - 1.6e-07 31.6 0.2 3.3e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain RhoGAP PF00620.22 KXX80059.1 - 1e-15 57.6 0.0 2.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain AP_endonuc_2 PF01261.19 KXX80061.1 - 3.9e-33 114.5 0.0 6.2e-33 113.8 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 KXX80061.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus PTS_2-RNA PF01885.11 KXX80063.1 - 9.6e-14 51.1 0.0 2.3e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KXX80063.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 La domain Methyltransf_31 PF13847.1 KXX80064.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80064.1 - 7e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80064.1 - 8.5e-05 22.9 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX80064.1 - 0.0002 21.1 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX80064.1 - 0.00081 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX80064.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX80064.1 - 0.023 15.0 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 6PGD PF00393.14 KXX80065.1 - 1.6e-69 234.3 0.0 2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KXX80065.1 - 2.1e-29 102.4 0.1 5e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KXX80065.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KXX80065.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 KXX80065.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.11 KXX80065.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Metallophos PF00149.23 KXX80066.1 - 6.1e-08 32.2 2.0 2.2e-07 30.4 1.3 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.19 KXX80066.1 - 0.00034 20.6 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NIF PF03031.13 KXX80067.1 - 5.3e-37 126.9 0.0 7.7e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Transposase_22 PF02994.9 KXX80067.1 - 0.051 12.0 0.7 0.099 11.1 0.5 1.4 1 0 0 1 1 1 0 L1 transposable element Myosin_head PF00063.16 KXX80068.1 - 1.4e-246 819.9 0.1 5.6e-246 817.9 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KXX80068.1 - 4.9e-27 94.0 281.6 6.7e-26 90.3 54.8 6.9 2 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 KXX80068.1 - 3.3e-07 29.8 0.6 8.7e-07 28.5 0.4 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.5 KXX80068.1 - 0.003 17.5 13.3 0.003 17.5 9.2 17.5 4 3 15 19 19 19 3 Cortexillin I, coiled coil AAA_19 PF13245.1 KXX80068.1 - 0.037 13.7 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain HemX PF04375.9 KXX80069.1 - 0.0019 16.8 0.0 0.004 15.8 0.0 1.5 1 0 0 1 1 1 1 HemX Reo_sigmaC PF04582.7 KXX80069.1 - 0.0032 16.6 0.7 0.0032 16.6 0.5 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein COG2 PF06148.6 KXX80069.1 - 0.0082 16.0 0.8 0.17 11.7 0.1 2.5 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 KXX80069.1 - 0.079 12.7 4.1 2.3 8.0 0.7 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_isomerase PF00160.16 KXX80070.1 - 2e-52 177.4 0.0 2.4e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavoprotein PF02441.14 KXX80071.1 - 0.0033 17.0 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Sgf11 PF08209.6 KXX80071.1 - 2.5 7.4 7.9 0.19 11.0 2.2 1.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) EST1_DNA_bind PF10373.4 KXX80072.1 - 1.3e-14 54.0 0.0 1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Rad50_zn_hook PF04423.9 KXX80072.1 - 0.074 12.5 0.8 0.19 11.2 0.5 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Oxysterol_BP PF01237.13 KXX80073.1 - 2.2e-127 424.4 0.0 9.5e-127 422.3 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KXX80073.1 - 2.5e-18 66.1 0.0 7.7e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX80073.1 - 2.6e-17 62.4 0.4 4.6e-10 39.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX80073.1 - 4.3e-17 60.9 0.0 3.5e-06 26.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KXX80073.1 - 6.9e-16 58.2 0.0 1.6e-08 34.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX80073.1 - 3.5e-13 48.3 0.1 5.7e-05 22.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 KXX80073.1 - 1.9e-11 44.0 0.4 3.8e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KXX80073.1 - 3.9e-08 33.2 1.1 1e-07 31.9 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.1 KXX80074.1 - 1.1e-46 159.6 1.6 1.5e-46 159.2 1.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KXX80074.1 - 3.6e-24 84.8 0.0 1.3e-11 44.2 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.17 KXX80074.1 - 0.03 14.4 0.1 5 7.3 0.1 2.4 2 0 0 2 2 2 0 Thioesterase superfamily zf-C3H1 PF10650.4 KXX80075.1 - 1.6e-06 27.4 3.1 3.6e-06 26.3 2.1 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain DUF4140 PF13600.1 KXX80075.1 - 6.3 7.3 17.1 1.3 9.5 0.8 4.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) GIT_SHD PF08518.6 KXX80076.1 - 3.4e-21 74.2 4.5 1.8e-12 46.4 1.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AAA_13 PF13166.1 KXX80076.1 - 0.059 11.8 18.2 0.12 10.8 12.6 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KXX80076.1 - 0.25 10.3 35.4 0.0066 15.5 13.9 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4407 PF14362.1 KXX80076.1 - 0.26 10.2 26.3 0.046 12.6 7.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) T2SF PF00482.18 KXX80076.1 - 0.38 10.6 7.9 2.7 7.9 3.8 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF1759 PF03564.10 KXX80076.1 - 0.87 9.3 9.1 0.06 13.1 0.5 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1759) CENP-K PF11802.3 KXX80076.1 - 1.1 8.4 13.2 2.2 7.4 9.2 1.5 1 0 0 1 1 1 0 Centromere-associated protein K Syntaxin_2 PF14523.1 KXX80076.1 - 9.8 6.2 21.3 5.2 7.1 0.0 4.6 4 1 1 5 5 5 0 Syntaxin-like protein MARVEL PF01284.18 KXX80077.1 - 2.1e-13 50.3 11.3 2.6e-13 49.9 7.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain CoxIIa PF08113.6 KXX80077.1 - 1.4 8.6 9.3 0.48 10.1 0.4 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IIa family DUF4305 PF14146.1 KXX80077.1 - 3.4 7.5 9.4 8.1 6.2 1.9 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) DUF2101 PF09874.4 KXX80077.1 - 7.9 5.9 10.2 9.5 5.6 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) SH3_9 PF14604.1 KXX80078.1 - 6.1e-09 35.3 0.2 1.2e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX80078.1 - 1.7e-08 33.6 0.1 2.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX80078.1 - 3.1e-05 23.3 0.0 6.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Med3 PF11593.3 KXX80078.1 - 7.3 5.7 16.7 15 4.6 11.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ssu72 PF04722.8 KXX80079.1 - 1.9e-84 281.8 0.0 2.2e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF3807 PF12720.2 KXX80080.1 - 1.9e-46 158.3 8.5 2.3e-46 158.1 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GAGA_bind PF06217.7 KXX80080.1 - 0.004 17.1 1.1 0.0046 16.9 0.8 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family ScpA_ScpB PF02616.9 KXX80080.1 - 0.12 11.8 1.4 0.17 11.4 1.0 1.1 1 0 0 1 1 1 0 ScpA/B protein Ribosomal_60s PF00428.14 KXX80080.1 - 0.31 11.4 8.3 0.13 12.7 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3682 PF12446.3 KXX80080.1 - 9.4 6.5 11.2 3.2 8.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) NAD_binding_1 PF00175.16 KXX80081.1 - 2.8e-31 108.3 0.0 1.9e-30 105.6 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KXX80081.1 - 4.8e-21 74.7 0.0 1.4e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KXX80081.1 - 4.5e-10 39.6 0.0 2.4e-05 24.3 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KXX80081.1 - 0.0022 17.9 0.0 0.0076 16.2 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Atg14 PF10186.4 KXX80082.1 - 4.6e-86 288.4 0.0 5.4e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF488 PF04343.8 KXX80083.1 - 0.2 12.0 2.0 0.88 9.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF488 DUF1129 PF06570.6 KXX80084.1 - 0.19 10.9 0.5 0.48 9.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cyd_oper_YbgE PF09600.5 KXX80084.1 - 0.35 11.0 4.5 0.71 10.0 3.1 1.4 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF940 PF06082.6 KXX80084.1 - 1 7.8 3.6 1.4 7.3 2.5 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Gti1_Pac2 PF09729.4 KXX80084.1 - 7.3 6.4 7.6 18 5.1 5.3 1.8 1 1 0 1 1 1 0 Gti1/Pac2 family Acyl_transf_3 PF01757.17 KXX80086.1 - 0.036 12.8 6.3 0.061 12.1 4.3 1.3 1 0 0 1 1 1 0 Acyltransferase family DUF1691 PF07950.6 KXX80086.1 - 0.065 13.1 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) DUF4131 PF13567.1 KXX80086.1 - 1 8.7 6.5 4.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WH2 PF02205.15 KXX80088.1 - 3.8e-10 39.0 1.6 4.4e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 WH2 motif PPP4R2 PF09184.6 KXX80089.1 - 2 7.8 4.6 3.8 6.9 0.8 2.1 2 0 0 2 2 2 0 PPP4R2 LSM PF01423.17 KXX80090.1 - 1.3e-14 53.4 0.0 1.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain HpcH_HpaI PF03328.9 KXX80091.1 - 1.8e-32 112.0 0.0 2.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 KXX80091.1 - 0.0072 15.5 1.2 4.7 6.3 0.0 3.2 3 2 0 3 3 3 2 Phosphoenolpyruvate phosphomutase DUF2156 PF09924.4 KXX80091.1 - 0.062 12.1 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) DUF1045 PF06299.7 KXX80091.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) DUF836 PF05768.9 KXX80092.1 - 1.1e-12 48.0 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KXX80092.1 - 0.0084 16.2 0.1 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 KXX80092.1 - 0.013 15.4 0.1 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin CHORD PF04968.7 KXX80093.1 - 2e-51 172.0 18.3 2.4e-26 91.7 3.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KXX80093.1 - 2.5e-14 53.5 0.0 4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 CS domain SMN PF06003.7 KXX80093.1 - 1.1 8.3 7.8 1.8 7.6 5.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RRM_1 PF00076.17 KXX80094.1 - 8.3e-40 134.2 0.0 3.8e-20 71.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80094.1 - 9.5e-32 108.8 0.0 7.2e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80094.1 - 1.9e-20 72.4 0.0 3e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX80094.1 - 0.056 13.2 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SDA1 PF05285.7 KXX80094.1 - 0.064 12.5 20.9 0.1 11.8 14.5 1.4 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KXX80094.1 - 0.15 10.5 18.1 0.17 10.3 12.5 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 KXX80094.1 - 0.2 9.3 5.9 0.22 9.1 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 KXX80094.1 - 0.4 8.5 26.2 0.53 8.1 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 KXX80094.1 - 1.1 7.8 6.8 1.2 7.6 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KXX80094.1 - 2.6 5.9 18.7 3.7 5.4 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KXX80094.1 - 3.3 7.3 26.7 5.4 6.6 18.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ycf1 PF05758.7 KXX80094.1 - 6.1 4.4 6.6 6.6 4.3 4.5 1.1 1 0 0 1 1 1 0 Ycf1 NDUFB10 PF10249.4 KXX80095.1 - 0.0011 19.1 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 KXX80095.1 - 0.056 13.8 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase CBFD_NFYB_HMF PF00808.18 KXX80096.1 - 5.6e-09 35.9 0.0 9.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KXX80096.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PPP4R2 PF09184.6 KXX80096.1 - 0.54 9.7 18.8 0.8 9.1 13.1 1.3 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 KXX80096.1 - 0.67 9.4 0.0 0.67 9.4 0.0 2.2 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.7 KXX80096.1 - 8.1 4.2 26.1 9.3 4.0 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family Herpes_gE PF02480.11 KXX80097.1 - 0.0013 17.0 0.0 0.0019 16.5 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 KXX80097.1 - 0.077 12.7 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Spc7_N PF15402.1 KXX80098.1 - 6.9e-280 931.1 57.5 3.4e-255 849.4 35.0 2.2 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KXX80098.1 - 9.8e-126 418.8 6.2 9.8e-126 418.8 4.3 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KXX80098.1 - 2.2e-16 59.2 1.8 4.2e-16 58.3 1.3 1.4 1 0 0 1 1 1 1 Spc7_C2 V_ATPase_I PF01496.14 KXX80098.1 - 0.18 9.6 1.8 0.32 8.8 1.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2115 PF09888.4 KXX80098.1 - 0.32 11.0 0.5 0.92 9.5 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Ribosomal_S17 PF00366.15 KXX80099.1 - 7.4e-31 106.0 1.1 1.2e-30 105.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RRM_1 PF00076.17 KXX80100.1 - 1.7e-17 62.7 0.1 2.7e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80100.1 - 8.8e-13 48.0 0.0 1.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80100.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KXX80100.1 - 0.073 12.5 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain SWI-SNF_Ssr4 PF08549.5 KXX80101.1 - 2.9e-242 805.7 9.9 3.6e-242 805.4 6.9 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 KXX80102.1 - 2.4e-134 447.1 0.0 3.2e-134 446.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KXX80102.1 - 5.1e-52 175.9 0.0 8.1e-52 175.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KXX80102.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TAFII55_N PF04658.8 KXX80103.1 - 7.2e-51 171.9 0.0 1.2e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 TAFII55 protein conserved region Vfa1 PF08432.5 KXX80103.1 - 6.9 6.6 9.1 2 8.3 1.0 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L37 PF08561.5 KXX80104.1 - 1.9e-32 110.6 4.1 2e-25 88.1 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 LUC7 PF03194.10 KXX80104.1 - 0.03 13.8 2.0 0.039 13.4 1.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Glyco_hydro_15 PF00723.16 KXX80105.1 - 8.5e-52 176.1 0.0 1.5e-49 168.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 IU_nuc_hydro PF01156.14 KXX80106.1 - 3.7e-58 197.2 0.0 4.2e-47 160.8 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase HLH PF00010.21 KXX80109.1 - 1.8e-13 49.9 0.5 4e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.17 KXX80110.1 - 7.1e-109 364.1 0.0 9e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FluMu_gp41 PF10109.4 KXX80111.1 - 0.041 13.8 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Rhomboid PF01694.17 KXX80114.1 - 2.4e-23 82.7 6.3 4.7e-23 81.8 4.4 1.4 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.5 KXX80115.1 - 2.3e-07 29.7 0.0 5.8e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase RNA_pol_Rpc4 PF05132.9 KXX80115.1 - 0.041 13.8 0.1 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Macoilin PF09726.4 KXX80115.1 - 0.93 7.6 1.4 10 4.2 2.5 1.5 2 0 0 2 2 2 0 Transmembrane protein TPT PF03151.11 KXX80116.1 - 4.1e-31 107.6 11.0 4.1e-31 107.6 7.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KXX80116.1 - 0.0084 15.0 21.1 0.008 15.1 13.0 1.9 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.15 KXX80116.1 - 0.019 15.0 36.1 0.29 11.1 8.1 3.6 2 2 1 3 3 3 0 EamA-like transporter family Bromo_TP PF07524.8 KXX80117.1 - 6.5e-06 25.7 0.0 2.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated zf-GRF PF06839.7 KXX80118.1 - 2.2e-07 30.6 6.9 4e-07 29.8 4.8 1.4 1 0 0 1 1 1 1 GRF zinc finger ELMO_CED12 PF04727.8 KXX80119.1 - 1.1e-51 174.8 0.0 2.4e-51 173.6 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 KXX80119.1 - 0.00018 21.2 0.1 0.027 14.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) FAD_binding_4 PF01565.18 KXX80120.1 - 2.3e-17 62.7 0.0 4.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain CRT10 PF08728.5 KXX80121.1 - 2e-19 69.1 0.0 1.4e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 CRT10 His_Phos_2 PF00328.17 KXX80122.1 - 4.1e-41 141.4 0.0 4.8e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3357 PF11837.3 KXX80122.1 - 0.07 12.9 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PTPA PF03095.10 KXX80123.1 - 2.1e-110 368.6 0.0 2.4e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NAD_kinase PF01513.16 KXX80125.1 - 4.5e-73 245.4 0.0 5.9e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Glyco_transf_28 PF03033.15 KXX80126.1 - 2.1e-22 79.3 0.0 1.6e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KXX80126.1 - 5e-05 22.0 0.0 8.3e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KXX80126.1 - 0.00061 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain KR PF08659.5 KXX80127.1 - 1.1e-58 197.8 0.6 2.2e-58 196.8 0.4 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX80127.1 - 3.4e-45 153.9 0.1 3.4e-45 153.9 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KXX80127.1 - 2.9e-13 49.5 0.0 5.8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX80127.1 - 1.1e-08 36.0 0.0 4.6e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX80127.1 - 3.4e-05 23.9 0.1 8.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KXX80127.1 - 0.00015 21.4 0.1 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 KXX80127.1 - 0.067 13.2 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PDZ PF00595.19 KXX80127.1 - 0.083 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Phage_Coat_A PF05357.8 KXX80127.1 - 0.17 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Phage Coat Protein A Zn_clus PF00172.13 KXX80128.1 - 0.0064 16.3 7.1 0.013 15.3 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 KXX80129.1 - 1.6e-23 83.7 0.1 2.2e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX80129.1 - 0.028 13.3 0.1 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 CsiD 7tm_2 PF00002.19 KXX80130.1 - 6.3e-07 28.7 9.0 6.3e-07 28.7 6.3 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KXX80130.1 - 0.018 13.9 3.9 0.032 13.1 2.7 1.5 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor VirB8 PF04335.8 KXX80130.1 - 0.13 11.7 5.6 0.54 9.8 0.1 2.8 3 0 0 3 3 3 0 VirB8 protein Cellulase PF00150.13 KXX80131.1 - 4.7e-40 137.5 0.1 5.5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pcc1 PF09341.5 KXX80132.1 - 2.6e-26 91.4 1.6 3.3e-26 91.1 1.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 KXX80133.1 - 6.7e-44 149.2 0.0 1e-40 138.9 0.0 3.3 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KXX80133.1 - 7.7e-17 61.1 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KXX80133.1 - 4.7e-07 29.3 0.0 9.1e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KXX80133.1 - 0.017 15.1 0.0 0.055 13.5 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KXX80133.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family SWIM PF04434.12 KXX80134.1 - 0.012 15.0 0.2 0.021 14.3 0.2 1.4 1 0 0 1 1 1 0 SWIM zinc finger Pkinase PF00069.20 KXX80135.1 - 5.6e-08 32.2 0.0 1.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80135.1 - 2.1e-06 27.0 0.0 3.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RNase_PH PF01138.16 KXX80136.1 - 2e-14 54.0 0.1 3.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KXX80136.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 WD40 PF00400.27 KXX80137.1 - 4.5e-54 178.5 26.9 4.5e-11 42.1 0.3 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KXX80137.1 - 1.9e-06 26.3 4.2 0.0095 14.1 0.2 3.5 2 2 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KXX80137.1 - 8.3e-06 25.6 0.0 0.00094 18.9 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KXX80137.1 - 0.0019 16.9 0.1 3.2 6.4 0.0 3.5 3 2 1 4 4 4 2 Nup133 N terminal like Apc4_WD40 PF12894.2 KXX80137.1 - 0.0085 15.5 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Exo_endo_phos PF03372.18 KXX80138.1 - 2.7e-18 66.8 0.0 4.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Oxysterol_BP PF01237.13 KXX80140.1 - 2.1e-88 296.1 0.0 2.9e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Abhydrolase_6 PF12697.2 KXX80141.1 - 4.3e-26 92.1 3.3 9e-26 91.1 2.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX80141.1 - 1.2e-11 44.5 0.0 5e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX80141.1 - 3.6e-09 36.5 0.1 2.4e-08 33.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX80141.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KXX80141.1 - 0.0042 17.3 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 KXX80141.1 - 0.014 14.6 0.0 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family UPF0227 PF05728.7 KXX80141.1 - 0.03 14.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KXX80141.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ammonium_transp PF00909.16 KXX80142.1 - 2.9e-114 381.6 28.7 3.3e-114 381.4 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 KXX80142.1 - 3.8 7.3 9.0 10 5.9 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) C2 PF00168.25 KXX80143.1 - 7.7e-79 259.6 1.5 1.1e-21 76.4 0.0 5.5 5 0 0 5 5 5 5 C2 domain zf-CCCH PF00642.19 KXX80144.1 - 7e-09 35.1 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KXX80144.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX80144.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 KXX80144.1 - 1 9.2 5.5 0.63 9.8 0.3 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Homeobox PF00046.24 KXX80145.1 - 1.8e-13 49.8 1.3 3.8e-13 48.8 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain FKBP_C PF00254.23 KXX80146.1 - 6.6e-31 106.1 0.0 3.9e-30 103.7 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 KXX80146.1 - 2.1e-19 69.6 0.0 1.5e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80146.1 - 1.2e-06 27.8 0.4 2.4e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Utp14 PF04615.8 KXX80146.1 - 1.7 6.7 40.2 0.53 8.3 13.6 2.2 2 0 0 2 2 2 0 Utp14 protein OCC1 PF15506.1 KXX80146.1 - 4.3 7.2 7.3 12 5.8 0.2 3.4 2 0 0 2 2 2 0 OCC1 family TT_ORF2 PF02957.10 KXX80147.1 - 3.5 8.3 6.5 0.95 10.1 0.1 2.5 3 0 0 3 3 3 0 TT viral ORF2 GRP PF07172.6 KXX80147.1 - 9.1 6.8 31.2 0.57 10.6 16.1 2.5 2 1 0 2 2 2 0 Glycine rich protein family UDPGP PF01704.13 KXX80148.1 - 6.8e-54 182.9 0.0 9.2e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KXX80148.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain HSP70 PF00012.15 KXX80151.1 - 1.1e-155 518.9 2.5 1.4e-155 518.6 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX80151.1 - 2.5e-12 46.0 0.6 3.6e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KXX80151.1 - 0.0087 14.9 0.9 0.014 14.2 0.1 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain RNA_pol_Rpb6 PF01192.17 KXX80151.1 - 0.035 13.8 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb6 Sporozoite_P67 PF05642.6 KXX80152.1 - 0.028 12.2 0.3 0.052 11.4 0.1 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen F-box PF00646.28 KXX80152.1 - 0.21 11.2 1.4 0.24 11.1 0.1 1.7 2 0 0 2 2 2 0 F-box domain HVSL PF09749.4 KXX80153.1 - 4e-64 215.8 0.0 2.6e-43 147.7 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised conserved protein Tmemb_cc2 PF10267.4 KXX80153.1 - 0.48 8.9 1.4 0.65 8.5 1.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pal1 PF08316.6 KXX80154.1 - 1.6e-10 41.5 0.0 4.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein DUF3682 PF12446.3 KXX80154.1 - 0.88 9.8 8.6 0.12 12.7 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) CPSF_A PF03178.10 KXX80155.1 - 1.8e-85 286.8 0.0 3.2e-85 286.0 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region LMBR1 PF04791.11 KXX80156.1 - 1.9e-13 49.8 15.1 8e-13 47.7 3.0 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein UDG PF03167.14 KXX80157.1 - 5.1e-24 84.4 0.4 1.6e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Med3 PF11593.3 KXX80157.1 - 0.32 10.1 6.4 0.41 9.8 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mpv17_PMP22 PF04117.7 KXX80158.1 - 6.4e-28 96.1 2.2 1e-27 95.5 1.5 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family ubiquitin PF00240.18 KXX80159.1 - 1.5e-17 62.7 0.1 2.1e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KXX80159.1 - 2.6e-09 36.6 1.4 6.8e-09 35.3 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain DUF2407 PF10302.4 KXX80159.1 - 0.00095 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 KXX80159.1 - 0.0061 16.2 0.3 0.009 15.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KXX80159.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like G-patch PF01585.18 KXX80161.1 - 0.047 13.4 1.4 0.22 11.3 0.9 2.1 1 1 0 1 1 1 0 G-patch domain CAF-1_p150 PF11600.3 KXX80161.1 - 0.5 9.7 35.2 0.68 9.2 24.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 KXX80161.1 - 0.78 7.9 13.3 0.98 7.6 9.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2796 PF10986.3 KXX80161.1 - 1.4 8.8 8.1 2 8.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) NAM-associated PF14303.1 KXX80161.1 - 9.1 6.5 28.0 19 5.5 19.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Bromodomain PF00439.20 KXX80162.1 - 7.2e-33 112.3 0.6 1.1e-15 57.2 0.4 2.4 2 0 0 2 2 2 2 Bromodomain BUD22 PF09073.5 KXX80162.1 - 0.00045 19.4 10.8 0.00069 18.8 7.5 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 KXX80162.1 - 0.0019 16.2 17.1 0.0025 15.8 11.8 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 KXX80162.1 - 0.0034 15.9 18.9 0.0049 15.4 13.1 1.2 1 0 0 1 1 1 1 Daxx Family TFIIA PF03153.8 KXX80162.1 - 0.0052 16.7 9.2 0.0052 16.7 6.4 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 KXX80162.1 - 0.012 15.6 17.0 0.02 14.8 11.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.7 KXX80162.1 - 0.014 14.6 18.1 0.021 14.0 12.5 1.2 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 KXX80162.1 - 0.51 9.5 16.2 1.1 8.4 11.2 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 KXX80162.1 - 0.53 9.6 12.8 0.83 8.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 KXX80162.1 - 0.83 9.1 18.0 1.4 8.4 12.4 1.3 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 KXX80162.1 - 2.5 6.0 17.6 3.9 5.4 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KXX80162.1 - 5.2 7.0 16.0 9.6 6.2 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 KXX80162.1 - 5.7 5.5 24.9 8.9 4.9 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KXX80162.1 - 7.8 5.6 15.2 13 4.8 10.5 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpb1_1 PF04997.7 KXX80164.1 - 1.8e-109 366.0 0.0 3e-109 365.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KXX80164.1 - 4.3e-101 337.8 0.2 9.2e-101 336.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KXX80164.1 - 6.6e-71 237.6 0.0 1.5e-70 236.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KXX80164.1 - 4.1e-59 199.4 2.8 1e-58 198.2 1.8 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KXX80164.1 - 1.3e-46 158.2 0.0 4.4e-46 156.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KXX80164.1 - 4.4e-43 146.2 5.2 8.6e-43 145.2 3.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KXX80164.1 - 6.9e-37 125.4 0.1 1.8e-36 124.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Upf2 PF04050.9 KXX80164.1 - 0.023 14.4 1.6 0.052 13.3 1.1 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 RNA_pol_Rpb1_R PF05001.8 KXX80164.1 - 1.1 9.4 195.5 0.03 14.4 7.7 13.8 7 3 7 15 15 15 0 RNA polymerase Rpb1 C-terminal repeat Thg1C PF14413.1 KXX80166.1 - 1.8e-50 169.6 0.2 2.4e-50 169.2 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KXX80166.1 - 1.7e-48 163.7 0.0 2.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 KXX80167.1 - 1.7e-13 49.8 4.5 3.2e-05 23.6 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 KXX80167.1 - 1.4e-05 24.9 0.0 0.028 14.1 0.0 3.2 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KXX80167.1 - 0.025 14.0 0.1 0.099 12.0 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain ERO1 PF04137.10 KXX80168.1 - 1.2e-135 452.1 0.1 2.6e-135 451.0 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Spore_GerQ PF09671.5 KXX80168.1 - 0.017 14.7 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) CKS PF01111.14 KXX80169.1 - 1.1e-34 118.0 0.4 1.7e-34 117.4 0.3 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit AMP-binding PF00501.23 KXX80170.1 - 2.2e-71 240.4 0.0 3e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX80170.1 - 7.9e-11 42.7 0.2 1.7e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 KXX80171.1 - 3.9e-61 205.4 0.1 4.7e-61 205.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BolA PF01722.13 KXX80172.1 - 6.4e-29 99.7 0.4 7.6e-29 99.4 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 KXX80174.1 - 2.3e-58 197.2 0.1 4.7e-58 196.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KXX80174.1 - 8e-26 90.6 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KXX80174.1 - 3.2e-13 49.3 11.2 3.2e-13 49.3 7.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 KXX80174.1 - 1.7 8.5 10.0 0.22 11.3 3.4 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Cyclin_N PF00134.18 KXX80175.1 - 1.4e-39 134.5 1.0 5e-39 132.7 0.1 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KXX80175.1 - 3.2e-12 46.3 0.0 8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PAT1 PF09770.4 KXX80175.1 - 0.4 8.8 4.9 0.57 8.3 3.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myosin_head PF00063.16 KXX80176.1 - 2.1e-231 769.7 2.7 3.3e-231 769.0 1.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KXX80176.1 - 2.4e-40 137.9 0.0 6.5e-40 136.5 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KXX80176.1 - 4e-12 45.3 0.2 7.5e-12 44.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX80176.1 - 7.1e-09 35.1 0.0 1.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX80176.1 - 1.8e-06 27.3 0.0 4.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KXX80176.1 - 0.0012 18.3 10.5 0.041 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KXX80176.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 KXX80176.1 - 0.0071 15.6 0.1 2.9 7.1 0.0 2.3 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KXX80176.1 - 0.02 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF552 PF04472.7 KXX80176.1 - 0.022 14.6 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 KXX80176.1 - 0.052 14.3 0.0 0.2 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KXX80176.1 - 0.093 12.3 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KXX80176.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain EBV-NA3 PF05009.7 KXX80177.1 - 0.045 13.0 0.9 0.063 12.5 0.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Caudal_act PF04731.7 KXX80177.1 - 0.073 13.3 0.1 0.1 12.8 0.1 1.3 1 1 0 1 1 1 0 Caudal like protein activation region DUF349 PF03993.7 KXX80177.1 - 0.15 12.2 3.6 0.25 11.5 2.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) zf-DHHC PF01529.15 KXX80178.1 - 3e-35 121.1 0.0 4.4e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Vitelline_membr PF10542.4 KXX80178.1 - 0.035 13.7 0.3 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Transglut_core3 PF13471.1 KXX80178.1 - 0.04 13.7 1.1 0.078 12.7 0.7 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_transf_90 PF05686.7 KXX80179.1 - 1.7e-09 36.9 0.3 0.0062 15.2 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 Lactamase_B PF00753.22 KXX80180.1 - 1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_18 PF00704.23 KXX80181.1 - 4e-71 240.2 0.0 4.6e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pec_lyase_C PF00544.14 KXX80183.1 - 2.4e-41 141.4 7.2 3.7e-41 140.7 5.0 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KXX80183.1 - 7e-06 25.8 10.5 0.00014 21.6 7.2 2.2 1 1 0 1 1 1 1 Right handed beta helix region DUF3614 PF12267.3 KXX80183.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) NACHT PF05729.7 KXX80184.1 - 9.2e-05 22.1 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX80184.1 - 0.00043 20.3 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF829 PF05705.9 KXX80184.1 - 0.001 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF676 PF05057.9 KXX80184.1 - 0.0089 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_18 PF13238.1 KXX80184.1 - 0.035 14.4 0.0 0.91 9.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain PGAP1 PF07819.8 KXX80184.1 - 0.041 13.4 0.0 0.09 12.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_9 PF10081.4 KXX80184.1 - 0.069 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family AAA_22 PF13401.1 KXX80184.1 - 0.1 12.7 0.1 0.77 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.7 KXX80185.1 - 0.21 11.3 2.0 0.42 10.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 KXX80185.1 - 3.6 6.5 8.9 4.5 6.3 0.4 2.5 3 0 0 3 3 3 0 Tropomyosin IncA PF04156.9 KXX80185.1 - 7.3 6.1 5.9 47 3.5 4.1 2.2 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 KXX80186.1 - 0.0021 17.7 2.6 0.0021 17.7 1.8 7.5 1 1 7 8 8 8 2 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KXX80186.1 - 0.0042 16.7 10.9 0.0042 16.7 7.6 5.5 1 1 4 5 5 5 3 IncA protein DUF4472 PF14739.1 KXX80186.1 - 0.0051 17.2 12.2 0.0051 17.2 8.5 6.1 2 2 5 7 7 7 2 Domain of unknown function (DUF4472) ADIP PF11559.3 KXX80186.1 - 0.0073 16.2 4.8 0.0073 16.2 3.3 5.7 3 2 3 6 6 6 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KXX80186.1 - 0.045 12.9 1.3 0.092 11.9 0.5 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KXX80186.1 - 0.11 12.3 8.5 0.23 11.3 0.5 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KXX80186.1 - 1.9 8.7 8.1 2.1 8.6 0.0 3.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3292 PF11696.3 KXX80187.1 - 1.2e-219 730.4 0.0 1.4e-219 730.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PMI_typeI PF01238.16 KXX80188.1 - 2.5e-77 260.3 0.0 2.2e-76 257.2 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KXX80188.1 - 2.8e-06 26.7 0.3 0.0017 17.8 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KXX80188.1 - 1.1e-05 25.1 0.0 0.0011 18.6 0.0 2.3 1 1 1 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 KXX80188.1 - 0.0089 15.3 0.6 0.022 14.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) SET PF00856.23 KXX80189.1 - 0.0038 17.5 3.1 0.02 15.1 2.1 2.0 1 1 0 1 1 1 1 SET domain Ribosomal_60s PF00428.14 KXX80189.1 - 0.047 14.0 14.2 0.13 12.6 9.9 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein SAF PF08666.7 KXX80189.1 - 0.062 13.7 0.0 20 5.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain Noelin-1 PF12308.3 KXX80189.1 - 0.064 13.0 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein TPR_2 PF07719.12 KXX80189.1 - 0.081 12.8 3.2 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat LAM_C PF12544.3 KXX80189.1 - 0.083 12.9 1.3 0.17 11.9 0.3 1.8 2 0 0 2 2 2 0 Lysine-2,3-aminomutase TPR_1 PF00515.23 KXX80189.1 - 0.24 11.0 0.9 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80189.1 - 0.89 9.5 3.8 0.47 10.4 0.3 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Cytomega_UL84 PF06284.6 KXX80189.1 - 1 7.7 3.6 1.6 7.0 2.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Glyco_hydro_30 PF02055.11 KXX80190.1 - 1.9e-08 32.9 0.0 1.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 An_peroxidase PF03098.10 KXX80191.1 - 6e-28 97.5 0.0 8.3e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Oxidored_molyb PF00174.14 KXX80192.1 - 9.5e-40 135.7 0.0 2.5e-39 134.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KXX80192.1 - 4.4e-38 129.8 1.1 8.7e-38 128.9 0.8 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KXX80192.1 - 1.2e-20 74.1 0.3 5e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KXX80192.1 - 7.3e-18 64.1 0.2 1.6e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 KXX80192.1 - 5.6e-16 58.4 0.0 1.6e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KXX80192.1 - 0.071 13.0 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Aldo_ket_red PF00248.16 KXX80193.1 - 1.3e-61 207.9 0.0 1.5e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TMEM173 PF15009.1 KXX80195.1 - 0.028 13.2 1.5 0.039 12.7 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 Amidohydro_4 PF13147.1 KXX80196.1 - 5.3e-15 56.1 6.4 4.2e-08 33.5 0.0 3.5 3 1 0 3 3 3 3 Amidohydrolase Amidohydro_5 PF13594.1 KXX80196.1 - 1.2e-06 28.2 0.1 4.4e-06 26.4 0.1 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KXX80196.1 - 7.4e-06 25.8 0.3 0.00059 19.5 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.6 KXX80196.1 - 0.00014 21.2 0.0 0.00014 21.2 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family DUF2717 PF10911.3 KXX80197.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Fungal_trans PF04082.13 KXX80199.1 - 4.7e-23 81.3 0.1 6.6e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transglut_core3 PF13471.1 KXX80199.1 - 0.15 11.8 0.3 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily Rifin_STEVOR PF02009.11 KXX80200.1 - 0.039 13.6 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Yip1 PF04893.12 KXX80200.1 - 0.052 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 KXX80200.1 - 0.083 12.5 0.4 0.19 11.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain An_peroxidase PF03098.10 KXX80202.1 - 1.2e-63 215.3 0.0 5.2e-61 206.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase DUF2235 PF09994.4 KXX80203.1 - 4.3e-100 334.6 0.6 5.7e-100 334.2 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CLASP_N PF12348.3 KXX80204.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal Peptidase_C97 PF05903.9 KXX80204.1 - 0.043 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain LRAT PF04970.8 KXX80204.1 - 0.05 13.5 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase TPR_12 PF13424.1 KXX80207.1 - 9.9e-15 54.2 13.9 3.7e-06 26.7 1.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80207.1 - 1.8e-11 43.5 14.4 0.015 15.8 0.3 7.1 5 1 1 6 6 6 3 Tetratricopeptide repeat HET PF06985.6 KXX80207.1 - 2.1e-06 27.9 0.1 0.00019 21.6 0.0 2.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_16 PF13432.1 KXX80207.1 - 6e-06 26.7 12.4 9.4e-05 22.9 0.1 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80207.1 - 3.5e-05 24.0 6.8 0.0026 18.0 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KXX80207.1 - 0.0011 18.8 17.1 0.044 13.7 0.3 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80207.1 - 0.0029 17.4 11.3 0.2 11.6 0.1 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX80207.1 - 0.018 14.8 0.8 1.2 9.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KXX80207.1 - 0.072 12.7 1.3 0.29 10.7 0.2 2.6 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.9 KXX80207.1 - 2.2 8.9 24.1 4 8.1 2.6 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M14 PF00246.19 KXX80208.1 - 5.7e-75 252.4 0.0 7.5e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 KXX80208.1 - 3.7e-08 32.9 0.0 2.3e-07 30.3 0.0 2.3 3 0 0 3 3 3 1 Carboxypeptidase activation peptide Lipase_3 PF01764.20 KXX80208.1 - 0.038 13.6 0.1 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) adh_short PF00106.20 KXX80209.1 - 2.1e-19 70.0 0.0 3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX80209.1 - 1.5e-10 41.0 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX80209.1 - 9.4e-05 22.2 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX80209.1 - 0.00088 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX80209.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KXX80209.1 - 0.038 14.0 0.1 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding GMC_oxred_N PF00732.14 KXX80210.1 - 1.8e-53 181.5 0.0 2.5e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX80210.1 - 9e-31 107.1 0.0 1.4e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX80210.1 - 3.1e-06 26.3 0.1 0.019 13.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX80210.1 - 0.0001 21.3 0.0 0.0073 15.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KXX80210.1 - 0.0002 20.4 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KXX80210.1 - 0.0012 17.8 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KXX80210.1 - 0.0013 18.6 0.1 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX80210.1 - 0.0025 16.3 0.0 0.51 8.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KXX80210.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX80210.1 - 0.022 14.8 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Photo_RC PF00124.14 KXX80211.1 - 0.011 14.7 0.6 0.011 14.7 0.4 1.6 2 0 0 2 2 2 0 Photosynthetic reaction centre protein DUF981 PF06168.6 KXX80211.1 - 0.61 9.8 8.2 0.76 9.5 1.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF981) Glyco_hydro_11 PF00457.12 KXX80212.1 - 1.4e-64 216.8 19.9 1.7e-64 216.5 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 PYNP_C PF07831.8 KXX80213.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Glyco_hydro_31 PF01055.21 KXX80215.1 - 3.2e-157 523.8 3.7 4.2e-157 523.4 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AA_permease PF00324.16 KXX80215.1 - 4.7e-121 404.4 40.7 1.1e-120 403.1 28.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX80215.1 - 4.7e-34 117.6 35.7 7.4e-34 117.0 24.8 1.2 1 0 0 1 1 1 1 Amino acid permease Gal_mutarotas_2 PF13802.1 KXX80215.1 - 3e-08 33.3 0.3 8.9e-08 31.8 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like MoCF_biosynth PF00994.19 KXX80216.1 - 3.9e-30 104.1 0.0 1.2e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 KXX80217.1 - 5.5e-11 42.4 0.0 6.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein YukC PF10140.4 KXX80217.1 - 0.087 11.3 0.7 1.5 7.3 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Csm1 PF12539.3 KXX80217.1 - 0.12 12.9 0.6 0.21 12.0 0.3 1.5 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 ParA PF10609.4 KXX80218.1 - 1.1e-34 118.1 0.0 2e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KXX80218.1 - 6.4e-15 55.0 0.0 9.3e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KXX80218.1 - 4.1e-06 26.7 0.0 1.2e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KXX80218.1 - 1.4e-05 24.2 1.0 0.00037 19.6 0.4 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KXX80218.1 - 0.00014 21.3 0.1 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 KXX80218.1 - 0.00019 20.6 0.0 0.00042 19.4 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KXX80218.1 - 0.00073 19.1 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KXX80218.1 - 0.002 17.3 0.1 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 KXX80218.1 - 0.0048 16.4 0.1 0.0075 15.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX80218.1 - 0.0054 16.4 0.4 0.077 12.7 0.1 2.6 3 0 0 3 3 3 1 Part of AAA domain SRP54 PF00448.17 KXX80218.1 - 0.0096 15.3 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KXX80218.1 - 0.022 14.8 0.1 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KXX80218.1 - 0.024 13.8 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 KXX80218.1 - 0.026 13.3 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.17 KXX80218.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.1 KXX80218.1 - 0.045 13.7 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KXX80218.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KXX80218.1 - 0.053 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KXX80218.1 - 0.07 13.0 0.1 0.48 10.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.4 KXX80218.1 - 0.07 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KXX80218.1 - 0.079 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 KXX80218.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain YhjQ PF06564.7 KXX80218.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein AAA_14 PF13173.1 KXX80218.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.1 KXX80219.1 - 4.3e-43 146.9 0.4 4.3e-43 146.9 0.3 2.7 3 1 1 4 4 4 1 Extracellular mutant protein 11 SRP54 PF00448.17 KXX80220.1 - 2.2e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KXX80220.1 - 5.2e-06 27.2 0.0 3.1e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX80220.1 - 9.5e-05 22.4 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 KXX80220.1 - 0.0001 21.1 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein PRK PF00485.13 KXX80220.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KXX80220.1 - 0.00027 21.2 0.2 0.0017 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX80220.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KXX80220.1 - 0.00084 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KXX80220.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 KXX80220.1 - 0.0017 17.3 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.24 KXX80220.1 - 0.002 18.2 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KXX80220.1 - 0.0021 17.6 0.1 0.0072 15.9 0.1 1.8 2 1 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KXX80220.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KXX80220.1 - 0.0039 16.9 0.0 0.0087 15.7 0.0 1.6 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KXX80220.1 - 0.0048 16.7 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KXX80220.1 - 0.0054 16.6 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KXX80220.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KXX80220.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 KXX80220.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.12 KXX80220.1 - 0.021 14.1 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 KXX80220.1 - 0.032 13.9 0.2 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KXX80220.1 - 0.04 13.8 0.1 0.082 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain LpxK PF02606.9 KXX80220.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_5 PF07728.9 KXX80220.1 - 0.049 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KXX80220.1 - 0.056 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KXX80220.1 - 0.064 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 KXX80220.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KXX80220.1 - 0.077 12.7 0.5 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KXX80220.1 - 0.091 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ArsA_ATPase PF02374.10 KXX80220.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase KTI12 PF08433.5 KXX80220.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 KXX80220.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3644 PF12358.3 KXX80220.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) DUF258 PF03193.11 KXX80220.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 adh_short PF00106.20 KXX80221.1 - 2.6e-64 216.1 7.3 2.2e-32 112.2 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KXX80221.1 - 2.4e-32 112.0 2.2 5.5e-15 55.4 0.1 2.7 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 KXX80221.1 - 3.7e-32 110.2 0.0 7.2e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KXX80221.1 - 4.5e-11 42.6 0.0 2e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 KXX80221.1 - 7.4e-05 22.2 4.2 0.0079 15.6 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KXX80221.1 - 0.00052 19.1 1.0 0.012 14.7 0.3 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 KXX80221.1 - 0.044 14.0 0.6 7 6.9 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 KXX80221.1 - 1.4 8.5 6.5 3.1 7.3 0.7 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF500 PF04366.7 KXX80222.1 - 3.9e-34 116.8 0.0 7.2e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Bacteriocin_IId PF09221.5 KXX80222.1 - 1 9.3 0.0 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like LRR_4 PF12799.2 KXX80223.1 - 0.016 14.8 0.6 6.3 6.5 0.0 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Lactamase_B PF00753.22 KXX80225.1 - 4.3e-18 65.6 3.1 7.3e-18 64.9 2.2 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KXX80225.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Sulf_transp PF04143.9 KXX80226.1 - 1.8e-12 47.0 32.6 6e-08 32.5 8.9 4.2 4 1 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KXX80226.1 - 0.0011 18.6 5.6 0.0011 18.6 3.9 4.6 4 2 0 5 5 5 1 Domain of unknown function (DUF4341) Selenoprotein_S PF06936.6 KXX80226.1 - 0.035 13.6 0.3 0.055 13.0 0.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4131 PF13567.1 KXX80226.1 - 2.5 7.4 8.6 0.22 10.9 0.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Kelch_5 PF13854.1 KXX80227.1 - 2.7e-15 55.9 7.7 2.2e-13 49.8 0.7 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KXX80227.1 - 5.5e-09 35.6 2.0 0.008 15.9 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KXX80227.1 - 9.8e-08 31.9 8.0 0.00013 21.9 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KXX80227.1 - 2.4e-06 26.9 0.6 0.025 14.1 0.2 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 KXX80227.1 - 0.00025 21.1 0.3 0.032 14.4 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 KXX80227.1 - 0.016 14.9 3.2 4.5 7.1 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Vps5 PF09325.5 KXX80229.1 - 7.3e-15 54.8 1.7 1e-14 54.4 1.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KXX80229.1 - 9.3e-09 35.0 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.22 KXX80230.1 - 1.5e-51 174.5 0.0 2.6e-51 173.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KXX80230.1 - 8.2e-24 83.2 0.0 1.8e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KXX80230.1 - 1.3e-11 44.1 0.0 2.5e-10 40.0 0.0 2.7 1 1 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KXX80230.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Actin PF00022.14 KXX80232.1 - 7.8e-18 64.0 0.0 9.8e-15 53.8 0.0 2.5 3 0 0 3 3 3 2 Actin FtsA PF14450.1 KXX80232.1 - 0.08 12.7 0.0 0.28 11.0 0.0 2.1 3 0 0 3 3 3 0 Cell division protein FtsA HpaP PF09483.5 KXX80232.1 - 0.5 10.2 18.3 0.33 10.8 7.5 2.2 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Ribonuc_L-PSP PF01042.16 KXX80233.1 - 1.6e-26 92.4 0.0 1.9e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1967 PF09269.6 KXX80233.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) SMC_Nse1 PF07574.8 KXX80234.1 - 3.6e-42 144.2 0.0 4.5e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KXX80234.1 - 1.2e-12 47.5 10.1 1.9e-12 46.9 7.0 1.3 1 0 0 1 1 1 1 RING-like domain Mrr_N PF14338.1 KXX80234.1 - 0.018 15.0 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Mrr N-terminal domain zf-TAZ PF02135.11 KXX80234.1 - 0.053 13.5 6.4 0.1 12.6 4.5 1.4 1 0 0 1 1 1 0 TAZ zinc finger HTH_27 PF13463.1 KXX80234.1 - 0.053 13.8 0.1 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-C3HC4_3 PF13920.1 KXX80234.1 - 4.5 7.0 9.3 62 3.3 6.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX80234.1 - 9 6.2 8.9 16 5.4 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain Peptidase_S64 PF08192.6 KXX80235.1 - 0.27 9.5 0.9 0.47 8.7 0.6 1.3 1 1 0 1 1 1 0 Peptidase family S64 SPRY PF00622.23 KXX80236.1 - 1.9e-08 34.4 0.0 3e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 SPRY domain Myb_Cef PF11831.3 KXX80237.1 - 3.7e-60 203.0 11.9 3.7e-60 203.0 8.3 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KXX80237.1 - 9.7e-21 73.5 3.6 2e-09 37.3 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX80237.1 - 1.7e-20 72.8 7.8 1.4e-14 53.9 1.9 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain MFS_1 PF07690.11 KXX80238.1 - 5.9e-07 28.5 5.7 5.9e-07 28.5 3.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily GILT PF03227.11 KXX80240.1 - 2.1e-13 50.0 0.1 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Troponin-I_N PF11636.3 KXX80240.1 - 6.2 6.6 8.3 12 5.6 5.8 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 ADH_N PF08240.7 KXX80241.1 - 3.7e-27 94.2 1.2 8.5e-27 93.0 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX80241.1 - 2.5e-15 56.1 0.2 1.1e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KXX80241.1 - 0.023 14.0 0.3 0.068 12.5 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KXX80241.1 - 0.032 13.6 0.2 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KXX80241.1 - 0.034 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KXX80241.1 - 0.035 14.1 0.4 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX80241.1 - 0.056 13.5 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KXX80241.1 - 0.06 13.1 1.0 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 KXX80241.1 - 0.28 9.6 0.9 0.4 9.0 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein JAB PF01398.16 KXX80242.1 - 9.2e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KXX80242.1 - 0.00016 21.7 0.3 0.00026 21.0 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Utp21 PF04192.7 KXX80243.1 - 2.2e-78 262.6 0.0 3e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KXX80243.1 - 1.5e-23 81.7 29.4 4.1e-05 23.2 0.6 9.3 10 0 0 10 10 10 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KXX80243.1 - 2.6e-05 22.7 0.0 4.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KXX80243.1 - 6.3e-05 21.3 0.2 1.6 6.7 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KXX80243.1 - 0.04 12.6 0.1 5.8 5.5 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like His_Phos_2 PF00328.17 KXX80244.1 - 1.3e-132 442.3 0.0 1.7e-132 441.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KXX80244.1 - 9.1e-08 31.7 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF4023 PF13215.1 KXX80245.1 - 0.1 12.3 1.7 0.21 11.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) AA_permease PF00324.16 KXX80246.1 - 1.8e-111 372.8 37.0 2.3e-111 372.5 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX80246.1 - 2.1e-20 72.7 37.6 2.6e-20 72.3 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease Ndc1_Nup PF09531.5 KXX80247.1 - 0.18 10.1 3.4 0.27 9.6 2.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DcpS_C PF11969.3 KXX80248.1 - 4.4e-30 104.2 0.0 6.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KXX80248.1 - 3.1e-28 98.3 0.0 4.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Glyco_hydro_76 PF03663.9 KXX80249.1 - 2.4e-48 165.4 11.9 3.8e-48 164.7 8.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KXX80249.1 - 0.00019 20.5 0.1 0.076 12.0 0.0 2.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KXX80249.1 - 0.007 15.6 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_47 PF01532.15 KXX80249.1 - 0.056 12.1 0.0 6.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 TFCD_C PF12612.3 KXX80250.1 - 3.3e-34 118.0 1.6 7.1e-34 116.9 0.0 2.5 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal IFRD PF05004.8 KXX80250.1 - 0.0096 15.0 0.3 0.033 13.2 0.2 1.9 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.17 KXX80250.1 - 0.1 12.7 10.5 0.16 12.1 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat Pyridoxal_deC PF00282.14 KXX80251.1 - 1.3e-111 372.6 0.0 1.7e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.7 KXX80252.1 - 1.2e-114 383.5 15.1 3e-114 382.1 10.5 1.6 1 1 0 1 1 1 1 Calcium-activated chloride channel EIF_2_alpha PF07541.7 KXX80253.1 - 8.2e-37 125.4 0.0 1.7e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KXX80253.1 - 3e-13 49.6 0.7 5.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 KXX80254.1 - 9e-37 124.7 0.1 3e-18 65.3 0.0 5.1 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KXX80254.1 - 3.3e-18 66.3 4.5 5.9e-18 65.5 1.8 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase Mito_carr PF00153.22 KXX80255.1 - 1.6e-63 210.3 0.4 3.8e-20 71.3 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 KXX80256.1 - 1.4e-07 31.0 0.1 4.5e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KXX80256.1 - 1.6e-05 24.4 0.1 0.00034 20.1 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 SE PF08491.5 KXX80257.1 - 9.7e-88 293.5 0.0 1.3e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KXX80257.1 - 4.7e-10 38.9 0.5 9.3e-08 31.3 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KXX80257.1 - 2e-08 33.6 3.8 1.6e-06 27.3 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KXX80257.1 - 1.3e-06 27.5 2.4 6.4e-05 21.9 0.1 2.5 2 1 1 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KXX80257.1 - 1.8e-05 24.6 0.3 4.6e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KXX80257.1 - 7.6e-05 21.9 0.3 7.6e-05 21.9 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX80257.1 - 9.7e-05 21.3 0.6 9.7e-05 21.3 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KXX80257.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KXX80257.1 - 0.0002 21.3 0.2 0.0004 20.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX80257.1 - 0.00063 20.1 0.2 0.0014 18.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KXX80257.1 - 0.0026 17.8 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KXX80257.1 - 0.0058 16.3 0.2 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KXX80257.1 - 0.0062 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KXX80257.1 - 0.025 13.2 0.9 1.3 7.5 0.6 2.5 2 1 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 KXX80257.1 - 0.026 12.9 0.1 0.043 12.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KXX80257.1 - 0.032 13.9 0.1 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KXX80257.1 - 0.037 12.9 0.3 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KXX80257.1 - 0.042 13.6 1.8 0.056 13.2 0.4 1.8 2 0 0 2 2 1 0 ThiF family TPR_16 PF13432.1 KXX80258.1 - 1.4e-05 25.6 3.5 2.7 8.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX80258.1 - 0.002 17.7 0.0 0.95 9.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80258.1 - 0.0036 17.8 12.3 0.62 10.8 0.0 6.9 5 3 3 8 8 8 1 Tetratricopeptide repeat PPR PF01535.15 KXX80258.1 - 0.0095 15.8 1.3 53 4.1 0.0 5.2 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.1 KXX80258.1 - 0.013 15.4 0.2 6.6 6.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80258.1 - 0.022 15.0 4.4 0.81 10.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80258.1 - 0.078 12.9 0.5 29 4.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX80258.1 - 4.8 7.9 8.7 1 9.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 KXX80260.1 - 6.9e-22 77.9 0.2 1.2e-20 73.8 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KXX80260.1 - 2.2e-07 30.9 0.1 0.0003 20.6 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Zn_clus PF00172.13 KXX80262.1 - 1.7e-06 27.8 10.3 2.8e-06 27.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRI PF15325.1 KXX80262.1 - 8.3 7.4 6.7 1.8 9.5 0.5 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection DHquinase_I PF01487.10 KXX80263.1 - 5e-27 95.0 0.0 9.8e-27 94.0 0.0 1.4 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 KXX80263.1 - 3.6e-21 75.6 0.0 6.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 KXX80263.1 - 1.9e-15 56.6 0.1 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KXX80263.1 - 2.1e-11 44.0 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KXX80263.1 - 0.17 11.7 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 ThiF family Shisa PF13908.1 KXX80264.1 - 0.16 12.1 7.4 0.32 11.1 5.2 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PRCC PF10253.4 KXX80264.1 - 0.19 12.4 8.9 0.27 11.9 6.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting IncA PF04156.9 KXX80264.1 - 3.3 7.2 11.2 2.4 7.7 1.2 2.2 2 0 0 2 2 2 0 IncA protein Ycf1 PF05758.7 KXX80265.1 - 0.00052 17.8 8.4 0.00052 17.8 5.9 1.1 1 0 0 1 1 1 1 Ycf1 PAT1 PF09770.4 KXX80265.1 - 0.0038 15.5 46.0 0.0048 15.2 31.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KXX80265.1 - 0.0069 16.4 17.8 0.013 15.5 12.3 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.3 KXX80265.1 - 0.007 15.7 38.6 0.007 15.7 26.7 2.5 2 1 0 2 2 2 1 SprA-related family GAGA_bind PF06217.7 KXX80265.1 - 0.011 15.7 15.1 0.34 10.8 9.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family CDC45 PF02724.9 KXX80265.1 - 0.013 13.5 14.1 0.015 13.3 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 KXX80265.1 - 0.014 15.3 26.0 0.018 14.9 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.4 KXX80265.1 - 0.019 14.8 4.6 0.027 14.3 3.2 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family SPX PF03105.14 KXX80265.1 - 0.051 13.3 11.9 0.063 13.0 8.2 1.2 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.2 KXX80265.1 - 0.054 11.1 13.1 0.056 11.1 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.7 KXX80265.1 - 0.058 11.1 6.4 0.071 10.8 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med15 PF09606.5 KXX80265.1 - 0.075 11.2 48.1 0.095 10.8 33.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DHHW PF14286.1 KXX80265.1 - 0.075 12.3 8.0 0.093 12.0 5.5 1.3 1 0 0 1 1 1 0 DHHW protein Lin-8 PF03353.10 KXX80265.1 - 0.092 12.0 18.8 0.11 11.7 13.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.7 KXX80265.1 - 0.092 11.3 19.7 0.12 10.9 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.3 KXX80265.1 - 0.12 10.9 11.9 0.19 10.3 8.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 APG6 PF04111.7 KXX80265.1 - 0.13 11.2 30.6 1 8.3 18.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 LMBR1 PF04791.11 KXX80265.1 - 0.2 10.1 6.2 0.24 9.9 3.9 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Glyco_transf_15 PF01793.11 KXX80265.1 - 0.24 10.3 10.4 0.33 9.8 7.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Neur_chan_memb PF02932.11 KXX80265.1 - 0.24 11.2 9.5 0.28 11.0 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paf1 PF03985.8 KXX80265.1 - 0.26 10.0 27.9 0.39 9.3 19.3 1.2 1 0 0 1 1 1 0 Paf1 Plasmodium_Vir PF05795.6 KXX80265.1 - 0.27 10.3 3.0 0.34 10.0 2.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4045 PF13254.1 KXX80265.1 - 0.3 10.3 14.8 0.35 10.1 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Trypan_PARP PF05887.6 KXX80265.1 - 0.33 10.7 4.9 0.52 10.1 3.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM117 PF15388.1 KXX80265.1 - 0.4 9.8 23.5 0.57 9.3 16.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 VID27 PF08553.5 KXX80265.1 - 0.42 8.7 10.4 0.5 8.5 7.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 KXX80265.1 - 0.43 9.9 20.9 0.66 9.3 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Band_3_cyto PF07565.8 KXX80265.1 - 0.43 10.0 15.9 0.64 9.4 11.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.17 KXX80265.1 - 0.45 9.4 11.2 0.63 8.9 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pex16 PF08610.5 KXX80265.1 - 0.47 9.4 11.3 0.75 8.7 7.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Bunya_G1 PF03557.10 KXX80265.1 - 0.53 8.0 8.6 0.65 7.7 6.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 YjgP_YjgQ PF03739.9 KXX80265.1 - 0.58 8.8 2.9 0.6 8.7 2.0 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3449 PF11931.3 KXX80265.1 - 0.62 9.5 18.3 0.29 10.6 10.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) SMN PF06003.7 KXX80265.1 - 0.72 8.8 5.6 1.2 8.2 3.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Nop25 PF09805.4 KXX80265.1 - 0.8 9.7 30.0 0.095 12.7 16.8 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF1675 PF07897.6 KXX80265.1 - 0.85 9.4 14.0 1.4 8.7 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AUX_IAA PF02309.11 KXX80265.1 - 1.1 9.0 16.1 2 8.1 11.1 1.4 1 0 0 1 1 1 0 AUX/IAA family Raftlin PF15250.1 KXX80265.1 - 1.1 7.7 16.4 1.5 7.2 11.4 1.2 1 0 0 1 1 1 0 Raftlin CDK5_activator PF03261.10 KXX80265.1 - 1.1 8.4 11.3 1.4 8.2 7.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Peptidase_U57 PF05582.7 KXX80265.1 - 1.3 7.9 16.0 2.5 7.0 11.1 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Otopetrin PF03189.8 KXX80265.1 - 1.3 7.9 3.5 1.5 7.7 2.4 1.2 1 0 0 1 1 1 0 Otopetrin DUF1777 PF08648.7 KXX80265.1 - 2.1 8.0 22.2 0.19 11.4 9.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) CPSF100_C PF13299.1 KXX80265.1 - 2.3 8.4 15.8 3.9 7.6 11.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF874 PF05917.6 KXX80265.1 - 2.7 6.7 30.0 3.7 6.2 20.8 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Pal1 PF08316.6 KXX80265.1 - 3.6 8.0 8.7 7.9 6.9 6.0 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein Baculo_PP31 PF05311.6 KXX80265.1 - 3.6 6.7 18.4 5.7 6.1 12.7 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FLO_LFY PF01698.11 KXX80265.1 - 4.3 6.0 20.8 7.9 5.2 14.4 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_UL87 PF03043.9 KXX80265.1 - 5.6 5.2 10.0 8.4 4.6 7.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family PAP_assoc PF03828.14 KXX80266.1 - 1.7e-17 63.0 0.0 2.2e-16 59.5 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase TPR_1 PF00515.23 KXX80266.1 - 0.075 12.6 0.2 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIF_alpha PF05793.7 KXX80267.1 - 0.18 10.1 55.5 8.1 4.6 38.2 2.9 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 KXX80268.1 - 2.9e-18 66.5 3.1 2.9e-18 66.5 2.2 2.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex 2_5_RNA_ligase2 PF13563.1 KXX80270.1 - 2.1e-33 115.1 0.0 5.8e-33 113.7 0.0 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 KXX80270.1 - 5.3e-25 87.6 0.0 1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 KXX80270.1 - 4.2e-13 49.7 0.1 7.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 KXX80270.1 - 3.9e-11 42.9 0.2 9.7e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 KXX80270.1 - 3.8e-06 26.5 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KXX80270.1 - 0.00032 20.9 0.0 0.0008 19.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_hydro_61 PF03443.9 KXX80271.1 - 1.1e-62 211.6 0.1 1.3e-62 211.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 KXX80272.1 - 5.2e-103 344.9 42.5 6.3e-103 344.6 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KXX80272.1 - 3.1e-30 105.0 46.7 3.8e-30 104.7 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 KXX80272.1 - 0.018 15.1 0.1 0.018 15.1 0.0 4.6 4 1 0 4 4 4 0 PrgI family protein Arif-1 PF06770.6 KXX80272.1 - 8 5.7 9.8 2.8 7.2 1.3 2.5 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) NUDIX PF00293.23 KXX80273.1 - 1.1e-16 60.7 0.5 3.8e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Pribosyltran_N PF13793.1 KXX80274.1 - 9.2e-43 144.6 0.0 3.3e-41 139.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KXX80274.1 - 5.6e-34 117.5 0.0 1.8e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KXX80274.1 - 1.2e-06 28.2 0.3 0.0007 19.3 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain DUF2997 PF11211.3 KXX80274.1 - 0.2 11.0 0.6 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) XPG_I_2 PF12813.2 KXX80275.1 - 8.1e-64 215.4 0.0 1.4e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing HEAT_2 PF13646.1 KXX80275.1 - 9.6e-30 102.7 5.4 5.3e-16 58.6 0.1 4.2 3 2 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KXX80275.1 - 1.3e-17 62.4 13.7 0.0069 16.7 0.5 7.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KXX80275.1 - 6.8e-07 29.5 11.5 0.00082 19.7 0.1 5.8 5 2 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 KXX80275.1 - 9.8e-07 28.3 1.9 0.29 11.3 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Cohesin_HEAT PF12765.2 KXX80275.1 - 0.063 13.2 0.0 0.95 9.4 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion PAN_1 PF00024.21 KXX80276.1 - 0.034 13.9 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 PAN domain HTH_Tnp_Tc5 PF03221.11 KXX80277.1 - 7.4e-15 54.5 8.3 1.1e-06 28.3 0.0 5.7 5 1 0 5 5 5 3 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 KXX80277.1 - 1.8e-14 53.1 0.4 8.9e-14 50.9 0.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 KXX80277.1 - 2.7e-06 26.8 1.0 8.1e-06 25.3 0.7 1.9 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 KXX80277.1 - 0.0028 17.9 15.7 0.032 14.5 2.6 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX80277.1 - 0.0056 16.9 19.6 0.014 15.6 2.9 4.3 3 1 0 3 3 3 2 C2H2-type zinc finger Elf1 PF05129.8 KXX80277.1 - 0.077 12.7 2.9 0.13 11.9 0.4 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HTH_3 PF01381.17 KXX80277.1 - 0.24 11.2 0.2 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix Nipped-B_C PF12830.2 KXX80278.1 - 1.3e-45 155.3 4.4 2.5e-45 154.4 0.5 3.0 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KXX80278.1 - 6.2e-12 45.1 3.9 7.5e-11 41.7 0.7 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KXX80278.1 - 9.2e-07 28.4 0.9 0.17 12.0 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Corona_nucleoca PF00937.13 KXX80279.1 - 0.0047 15.9 7.2 0.0047 15.9 5.0 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein DUF1777 PF08648.7 KXX80279.1 - 2.1 8.0 20.1 0.43 10.3 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DUF2493 PF10686.4 KXX80281.1 - 0.0042 16.5 0.0 0.0099 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2493) Ras PF00071.17 KXX80282.1 - 9.3e-40 135.6 0.0 1.5e-37 128.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KXX80282.1 - 1.9e-18 67.1 0.0 2.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX80282.1 - 1.9e-09 36.9 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX80282.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KXX80282.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KXX80282.1 - 0.032 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KXX80282.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2411 PF10304.4 KXX80282.1 - 0.082 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) AAA_5 PF07728.9 KXX80282.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX80282.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KXX80282.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.13 KXX80283.1 - 8.6e-118 393.2 1.0 1.1e-117 392.9 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KXX80283.1 - 2.6e-24 84.8 0.0 5.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KXX80283.1 - 4.1e-07 29.2 0.1 6.3e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KXX80283.1 - 0.00047 19.1 0.6 0.0018 17.2 0.0 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KXX80283.1 - 0.00048 19.3 0.2 0.00072 18.7 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KXX80283.1 - 0.0024 17.1 0.6 0.14 11.3 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.7 KXX80283.1 - 0.069 12.0 0.0 1.5 7.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.9 KXX80283.1 - 0.1 11.6 0.1 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Coatomer_E PF04733.9 KXX80285.1 - 0.0045 16.2 0.1 0.009 15.2 0.1 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit DUF4192 PF13830.1 KXX80285.1 - 6.4 6.3 9.4 0.16 11.5 1.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) ResIII PF04851.10 KXX80286.1 - 2.5e-19 69.8 0.0 5e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KXX80286.1 - 1.6e-14 53.4 0.1 4.3e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX80286.1 - 3.4e-11 42.9 0.0 9.1e-11 41.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase LcrG PF07216.7 KXX80286.1 - 0.071 13.1 2.7 0.17 11.9 0.0 2.7 3 0 0 3 3 3 0 LcrG protein AF1Q PF15017.1 KXX80287.1 - 0.012 15.5 1.1 0.012 15.5 0.8 4.5 4 2 0 4 4 4 0 Drug resistance and apoptosis regulator Ribosomal_60s PF00428.14 KXX80287.1 - 0.012 15.9 2.9 0.012 15.9 2.0 4.6 6 0 0 6 6 6 0 60s Acidic ribosomal protein Myb_DNA-binding PF00249.26 KXX80287.1 - 0.026 14.5 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain PI3_PI4_kinase PF00454.22 KXX80288.1 - 1.4e-40 139.1 0.0 2.1e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Acetyltransf_1 PF00583.19 KXX80289.1 - 3.8e-09 36.4 0.0 8.1e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX80289.1 - 4.6e-06 26.7 0.0 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX80289.1 - 7.7e-05 22.3 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KXX80289.1 - 0.00013 22.0 0.0 0.00057 19.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX80289.1 - 0.00027 20.7 0.0 0.00063 19.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KXX80289.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Propep_M14 PF02244.11 KXX80289.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Zn_clus PF00172.13 KXX80290.1 - 0.011 15.6 12.2 0.02 14.7 8.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX80290.1 - 0.015 14.1 0.1 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.11 KXX80291.1 - 3e-29 101.8 9.6 5.1e-29 101.0 6.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX80291.1 - 3.1e-11 42.5 5.9 1.9e-10 39.9 3.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KXX80291.1 - 3e-05 22.6 13.9 0.00091 17.7 3.1 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 KXX80291.1 - 3.6e-05 22.0 6.6 0.00017 19.8 1.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.8 KXX80291.1 - 0.0069 14.6 1.1 0.011 13.9 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3611 PF12263.3 KXX80291.1 - 0.011 15.1 0.2 1.6 8.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) LacY_symp PF01306.14 KXX80291.1 - 0.039 12.5 2.0 0.039 12.5 0.2 1.7 2 0 0 2 2 2 0 LacY proton/sugar symporter Formyl_trans_N PF00551.14 KXX80292.1 - 1.3e-36 125.8 0.1 1.6e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KXX80292.1 - 1.6e-07 30.6 0.0 4.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KXX80292.1 - 0.00021 20.9 0.0 0.00054 19.6 0.0 1.8 1 0 0 1 1 1 1 ACT domain TroA PF01297.12 KXX80292.1 - 0.041 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family SSF PF00474.12 KXX80293.1 - 8.5e-18 64.1 30.0 8.5e-18 64.1 20.8 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_3 PF00933.16 KXX80294.1 - 7.8e-93 310.7 0.0 1.1e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX80294.1 - 3.1e-52 177.3 0.2 5.6e-51 173.2 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX80294.1 - 2.8e-25 88.0 0.1 5.8e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CFEM PF05730.6 KXX80295.1 - 6.1e-12 45.1 7.0 8e-12 44.8 4.9 1.2 1 0 0 1 1 1 1 CFEM domain HCV_NS1 PF01560.12 KXX80296.1 - 0.14 10.5 0.7 0.13 10.6 0.5 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 SH3_1 PF00018.23 KXX80297.1 - 1.4e-09 37.2 0.1 2.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX80297.1 - 1.7e-07 30.6 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KXX80297.1 - 8.1e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAD-SLDH PF12318.3 KXX80298.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4140 PF13600.1 KXX80298.1 - 0.13 12.6 3.8 32 5.0 0.5 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Aa_trans PF01490.13 KXX80299.1 - 2.5e-88 296.2 9.6 3.7e-88 295.7 6.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KXX80299.1 - 0.00044 19.1 13.5 0.00083 18.2 9.4 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.14 KXX80300.1 - 4.7e-25 87.0 0.1 7.7e-25 86.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S16 YjeF_N PF03853.10 KXX80301.1 - 2e-34 118.6 0.0 2.5e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ABC_sub_bind PF04392.7 KXX80301.1 - 0.09 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Glyco_hydro_16 PF00722.16 KXX80302.1 - 2.8e-37 127.8 0.5 4.8e-37 127.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.17 KXX80303.1 - 7.9e-51 173.0 0.0 1.8e-50 171.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KXX80304.1 - 5.1e-06 26.0 0.1 1.5e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like PLA2_B PF01735.13 KXX80305.1 - 0.072 11.2 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain EHN PF06441.7 KXX80310.1 - 8.1e-31 106.2 0.1 1.5e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KXX80310.1 - 1.5e-08 34.7 1.0 2.9e-08 33.8 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX80310.1 - 0.0015 18.0 2.5 0.0022 17.5 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Clr5 PF14420.1 KXX80311.1 - 2.5e-10 40.0 0.1 3.3e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.19 KXX80313.1 - 3.9e-76 256.4 21.2 4.7e-76 256.1 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX80313.1 - 1.6e-17 63.2 22.4 1.6e-17 63.2 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NIPSNAP PF07978.8 KXX80314.1 - 2e-38 130.4 0.5 3.5e-28 97.5 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.4 KXX80314.1 - 0.047 13.1 5.4 0.074 12.5 3.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FSH1 PF03959.8 KXX80315.1 - 8.4e-57 192.0 0.0 1.1e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KXX80315.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX80315.1 - 4.5e-06 26.6 0.1 0.0029 17.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX80315.1 - 0.00021 20.7 0.0 0.15 11.4 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 KXX80315.1 - 0.11 11.7 0.0 9.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Rpp20 PF12328.3 KXX80316.1 - 3.3e-27 94.9 0.9 4.2e-27 94.5 0.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KXX80316.1 - 4.6e-17 61.3 0.1 8.3e-17 60.5 0.1 1.4 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.4 KXX80317.1 - 1.5e-74 250.5 0.0 6.4e-42 143.5 0.1 2.0 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein ABC2_membrane PF01061.19 KXX80318.1 - 1.3e-93 312.0 49.2 1.8e-48 164.5 10.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KXX80318.1 - 1.2e-39 135.7 0.1 2.1e-19 70.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KXX80318.1 - 2.4e-28 97.8 0.0 6.4e-24 83.5 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KXX80318.1 - 3.2e-07 30.3 0.0 9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KXX80318.1 - 5.9e-06 26.2 0.1 0.096 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KXX80318.1 - 1.5e-05 25.1 0.1 0.36 10.9 0.0 3.9 3 1 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 KXX80318.1 - 1.6e-05 24.1 25.7 6e-05 22.2 5.0 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KXX80318.1 - 3.3e-05 23.3 0.0 0.019 14.3 0.0 3.1 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 KXX80318.1 - 3.5e-05 23.0 0.1 0.00047 19.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KXX80318.1 - 4.3e-05 23.0 0.0 0.35 10.3 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 KXX80318.1 - 7.9e-05 22.7 0.9 0.066 13.1 1.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KXX80318.1 - 0.00027 20.4 0.3 0.17 11.4 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KXX80318.1 - 0.00048 20.4 0.0 0.017 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KXX80318.1 - 0.0008 18.9 0.1 0.019 14.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KXX80318.1 - 0.0009 19.1 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KXX80318.1 - 0.00091 19.2 4.8 0.0086 16.0 0.2 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_28 PF13521.1 KXX80318.1 - 0.002 18.1 0.3 0.0059 16.5 0.2 1.8 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KXX80318.1 - 0.0026 17.3 0.3 0.13 11.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KXX80318.1 - 0.0027 18.5 0.0 0.078 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KXX80318.1 - 0.011 15.4 0.1 1.1 8.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KXX80318.1 - 0.027 13.7 0.3 0.33 10.1 0.1 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KXX80318.1 - 0.028 13.8 0.5 7.4 5.9 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KXX80318.1 - 0.057 12.9 0.2 0.28 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KXX80318.1 - 0.061 13.0 0.0 5 6.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 KXX80318.1 - 0.08 12.0 0.2 0.99 8.4 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 KXX80318.1 - 0.083 11.8 0.1 0.36 9.8 0.1 1.9 2 0 0 2 2 2 0 Septin AAA PF00004.24 KXX80318.1 - 0.085 13.0 0.0 22 5.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KXX80318.1 - 0.11 11.9 0.2 0.32 10.4 0.2 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 KXX80318.1 - 0.15 10.9 0.1 5.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3952 PF13130.1 KXX80318.1 - 0.19 11.6 0.2 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) NB-ARC PF00931.17 KXX80318.1 - 0.21 10.4 0.6 2.5 6.8 0.1 2.3 3 0 0 3 3 3 0 NB-ARC domain Dynamin_N PF00350.18 KXX80318.1 - 0.22 11.3 0.2 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Cupin_2 PF07883.6 KXX80319.1 - 5.7e-08 32.1 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain FAD_binding_3 PF01494.14 KXX80322.1 - 6.6e-11 41.8 0.1 3.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KXX80322.1 - 6.4e-08 32.5 0.5 3e-07 30.3 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX80322.1 - 8.4e-07 28.2 2.4 2.5e-05 23.3 0.3 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX80322.1 - 8.9e-05 22.6 0.0 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX80322.1 - 9.9e-05 21.3 1.3 9.9e-05 21.3 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX80322.1 - 0.00039 20.3 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX80322.1 - 0.0012 17.8 0.9 0.0017 17.3 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KXX80322.1 - 0.0018 18.6 1.5 0.047 14.1 0.3 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX80322.1 - 0.0026 16.3 0.0 0.0063 15.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KXX80322.1 - 0.0065 16.0 1.7 0.012 15.1 0.2 2.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KXX80322.1 - 0.03 13.3 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KXX80322.1 - 0.037 13.1 0.1 0.07 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 KXX80322.1 - 0.075 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_bind_1 PF00187.14 KXX80323.1 - 1.7e-15 56.7 72.5 2.7e-07 30.4 11.2 4.5 3 2 0 3 3 3 3 Chitin recognition protein DUF2360 PF10152.4 KXX80323.1 - 0.25 11.6 1.3 2.8 8.1 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SOG2 PF10428.4 KXX80323.1 - 0.85 8.1 8.9 1.2 7.6 6.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Conotoxin PF02950.12 KXX80323.1 - 2.8 8.8 18.6 1.7 9.5 0.6 3.7 3 0 0 3 3 3 0 Conotoxin MIP PF00230.15 KXX80324.1 - 6.5e-49 166.4 15.9 8.5e-49 166.0 11.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cofilin_ADF PF00241.15 KXX80325.1 - 2.4e-17 62.9 0.0 2.7e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DASH_Spc19 PF08287.6 KXX80326.1 - 2.1e-42 144.2 0.0 3.1e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Spc19 Lzipper-MIP1 PF14389.1 KXX80326.1 - 0.33 11.1 3.9 1.4 9.0 2.8 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 bZIP_1 PF00170.16 KXX80327.1 - 2.6e-10 40.0 9.5 3.8e-10 39.5 6.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX80327.1 - 2.8e-08 33.4 14.7 3.9e-08 32.9 9.6 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KXX80327.1 - 0.00024 21.3 6.4 0.00037 20.7 4.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor SR-25 PF10500.4 KXX80327.1 - 0.00085 18.8 0.7 0.001 18.6 0.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4140 PF13600.1 KXX80327.1 - 0.031 14.7 3.6 0.054 13.9 2.5 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pyocin_S PF06958.7 KXX80327.1 - 0.066 13.5 1.5 0.1 12.9 1.0 1.4 1 0 0 1 1 1 0 S-type Pyocin TPD52 PF04201.10 KXX80327.1 - 0.13 11.9 2.3 0.23 11.1 1.6 1.5 1 0 0 1 1 1 0 Tumour protein D52 family WD40_alt PF14077.1 KXX80327.1 - 0.23 11.1 4.0 3.1 7.4 0.2 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif Atg14 PF10186.4 KXX80327.1 - 0.35 9.7 5.9 0.42 9.5 4.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Takusan PF04822.8 KXX80327.1 - 0.37 10.5 3.2 0.59 9.9 2.2 1.3 1 0 0 1 1 1 0 Takusan MCC-bdg_PDZ PF10506.4 KXX80327.1 - 0.62 9.9 4.3 2.4 8.0 0.5 2.5 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1192 PF06698.6 KXX80327.1 - 4.5 7.1 8.9 9.7 6.0 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF4286 PF14114.1 KXX80330.1 - 0.07 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) HNH_2 PF13391.1 KXX80332.1 - 1.1e-10 41.1 0.3 2.3e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-C2H2_4 PF13894.1 KXX80333.1 - 3 8.3 7.4 12 6.5 0.3 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger BTB PF00651.26 KXX80335.1 - 0.00089 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HET PF06985.6 KXX80337.1 - 1.5e-19 70.5 5.9 9.7e-17 61.4 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Na_H_Exchanger PF00999.16 KXX80338.1 - 2.7e-45 154.5 23.0 3.1e-45 154.3 15.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p450 PF00067.17 KXX80339.1 - 3.8e-40 137.8 0.0 1.1e-32 113.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ank PF00023.25 KXX80339.1 - 1.3e-22 78.3 0.0 3.3e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KXX80339.1 - 9.8e-21 73.9 0.0 2.1e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX80339.1 - 2.2e-19 69.4 0.0 1.3e-09 38.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX80339.1 - 1.1e-17 62.3 0.0 0.00015 21.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX80339.1 - 9.7e-15 54.2 0.0 6e-09 35.8 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) FAR1 PF03101.10 KXX80339.1 - 5.7e-05 23.5 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF3237 PF11578.3 KXX80340.1 - 9.7e-26 89.8 0.5 4.3e-25 87.7 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) End_beta_barrel PF12195.3 KXX80340.1 - 0.074 12.8 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Pkinase PF00069.20 KXX80341.1 - 1.9e-29 102.6 0.0 2.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80341.1 - 4.3e-06 25.9 0.2 8.3e-05 21.7 0.1 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX80341.1 - 0.018 14.8 0.2 0.34 10.6 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_2 PF00891.13 KXX80342.1 - 1.1e-24 86.9 0.1 1.6e-24 86.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.11 KXX80343.1 - 1.1e-35 123.0 51.6 2.8e-34 118.3 35.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX80343.1 - 0.00025 19.7 13.4 0.00025 19.7 9.3 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter Pkinase PF00069.20 KXX80345.1 - 7.9e-31 107.1 0.0 1.8e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80345.1 - 1.7e-05 24.0 0.1 0.0019 17.2 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KXX80345.1 - 0.012 15.3 0.5 0.023 14.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_25 PF01755.12 KXX80346.1 - 7e-08 32.3 0.0 2.1e-06 27.5 0.0 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_hydro_11 PF00457.12 KXX80347.1 - 5.9e-48 162.6 7.7 6.9e-48 162.4 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Tyrosinase PF00264.15 KXX80348.1 - 1.6e-30 106.9 0.1 3e-30 106.0 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.23 KXX80349.1 - 4e-80 270.0 0.0 7.9e-72 242.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX80349.1 - 2e-08 34.0 0.2 3.7e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX80349.1 - 0.0007 19.5 0.2 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX80349.1 - 0.0015 18.3 0.1 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX80349.1 - 0.0036 16.5 0.1 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KXX80349.1 - 0.0051 16.0 0.1 0.0085 15.3 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase GMC_oxred_C PF05199.8 KXX80350.1 - 2.1e-23 83.1 0.2 4e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KXX80350.1 - 1.9e-22 79.8 0.0 4.6e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX80350.1 - 5.6e-08 32.0 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX80350.1 - 1e-06 27.8 0.3 3.2e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX80350.1 - 6.9e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX80350.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX80350.1 - 0.0019 16.7 0.1 0.0028 16.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KXX80350.1 - 0.002 18.2 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 KXX80350.1 - 0.0041 17.0 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 DOMON domain Thi4 PF01946.12 KXX80350.1 - 0.031 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KXX80350.1 - 0.083 11.7 0.7 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX80350.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 KXX80350.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.20 KXX80351.1 - 8e-21 74.3 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80351.1 - 1.9e-09 36.9 0.0 9.8e-09 34.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX80351.1 - 0.0049 16.6 0.8 0.52 10.0 0.0 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.9 KXX80352.1 - 7.4e-44 150.1 0.2 9.1e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ferritin_2 PF13668.1 KXX80353.1 - 5.3e-17 62.0 0.0 9.7e-17 61.1 0.0 1.4 2 0 0 2 2 2 1 Ferritin-like domain DUF1353 PF07087.6 KXX80355.1 - 0.37 10.2 1.6 0.35 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) DUF427 PF04248.7 KXX80359.1 - 1.8e-28 98.0 0.2 4.3e-28 96.8 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF427) HET PF06985.6 KXX80360.1 - 5e-06 26.7 1.6 0.0022 18.1 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4343 PF14243.1 KXX80360.1 - 0.0051 16.6 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4343) NAD_binding_10 PF13460.1 KXX80361.1 - 9.2e-07 29.0 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KXX80361.1 - 0.0004 19.3 0.0 1.2 7.9 0.0 2.8 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KXX80361.1 - 0.04 12.6 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4066 PF13278.1 KXX80362.1 - 3.9e-19 68.5 0.0 9.2e-19 67.3 0.0 1.5 2 0 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX80362.1 - 1.7e-10 40.5 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KXX80362.1 - 0.066 12.6 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I FAD_binding_3 PF01494.14 KXX80363.1 - 0.0017 17.4 4.9 0.04 12.9 0.6 2.2 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KXX80363.1 - 0.0038 17.2 2.3 0.0038 17.2 1.6 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX80363.1 - 0.42 10.3 2.5 1.9 8.2 0.7 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX80363.1 - 0.55 10.2 2.6 0.49 10.4 1.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX80363.1 - 0.94 9.9 3.3 0.64 10.4 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX80363.1 - 7.2 5.4 6.7 5.1 5.8 2.9 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KXX80364.1 - 2.4e-09 36.7 0.0 2.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KXX80364.1 - 0.0028 16.5 0.0 0.005 15.7 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase DUF3237 PF11578.3 KXX80366.1 - 1.6e-23 82.6 0.0 4.8e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) NACHT PF05729.7 KXX80367.1 - 1.6e-05 24.6 0.0 4.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KXX80367.1 - 0.00023 21.3 0.0 0.0021 18.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.2 KXX80367.1 - 0.00031 20.7 0.3 0.003 17.4 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KXX80367.1 - 0.00055 19.9 0.1 0.019 14.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 KXX80367.1 - 0.0059 15.6 0.1 2.2 7.1 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain DUF676 PF05057.9 KXX80367.1 - 0.0078 15.5 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_25 PF13481.1 KXX80367.1 - 0.026 13.9 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX80367.1 - 0.031 14.4 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase PGAP1 PF07819.8 KXX80367.1 - 0.033 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_30 PF13604.1 KXX80367.1 - 0.038 13.5 0.2 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KXX80367.1 - 0.062 12.2 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 KXX80367.1 - 0.071 13.9 0.0 0.71 10.7 0.0 2.6 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.1 KXX80367.1 - 0.093 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KXX80367.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) p450 PF00067.17 KXX80368.1 - 3.7e-58 197.1 0.0 5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 KXX80370.1 - 1.2e-27 97.2 0.1 2.1e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAP PF07174.6 KXX80370.1 - 0.1 11.9 1.7 0.15 11.3 1.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MFS_1 PF07690.11 KXX80371.1 - 1e-27 96.8 4.0 1e-27 96.8 2.8 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.1 KXX80372.1 - 1.7e-38 130.4 10.6 4e-10 39.4 0.0 6.3 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KXX80372.1 - 3.7e-21 74.3 24.6 6.9e-05 22.6 0.0 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KXX80372.1 - 3.3e-08 33.9 12.7 0.095 13.4 0.0 6.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX80372.1 - 5.3e-08 32.3 6.5 0.012 15.2 0.0 5.5 4 2 1 5 5 5 2 TPR repeat TPR_4 PF07721.9 KXX80372.1 - 7.9e-07 28.9 29.8 0.036 14.4 0.2 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80372.1 - 2.4e-06 27.7 18.3 1.4 9.3 2.5 6.9 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80372.1 - 1.8e-05 24.2 25.4 0.72 9.9 0.3 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat AAA_22 PF13401.1 KXX80372.1 - 0.0001 22.4 0.0 0.00095 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KXX80372.1 - 0.0002 20.8 3.4 0.99 9.3 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX80372.1 - 0.0003 21.0 15.6 1.5 9.4 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.7 KXX80372.1 - 0.00051 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 KXX80372.1 - 0.00099 18.7 14.7 0.17 11.7 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat NB-ARC PF00931.17 KXX80372.1 - 0.0036 16.1 0.0 0.02 13.7 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KXX80372.1 - 0.0037 17.3 1.6 24 5.1 0.0 4.9 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 KXX80372.1 - 0.0077 16.2 0.2 0.073 13.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain TPR_14 PF13428.1 KXX80372.1 - 0.13 12.9 40.0 10 7.1 0.2 9.6 7 2 3 10 10 8 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 KXX80372.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TPR_21 PF09976.4 KXX80372.1 - 0.61 10.0 3.3 1.4 8.8 0.6 2.9 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX80372.1 - 2.7 7.7 19.0 4.7 6.9 0.1 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF2945 PF11160.3 KXX80373.1 - 0.051 13.3 1.6 0.1 12.4 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) Amidase PF01425.16 KXX80374.1 - 9.3e-69 232.3 0.0 1.1e-68 232.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KXX80375.1 - 1.2e-08 34.4 0.0 2.4e-07 30.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80375.1 - 2.9e-05 23.2 0.0 0.00026 20.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.13 KXX80376.1 - 0.27 11.1 7.4 0.84 9.5 5.1 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4246 PF14033.1 KXX80377.1 - 2.5e-161 537.7 0.0 3e-161 537.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KXX80377.1 - 0.0079 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.19 KXX80378.1 - 7e-113 377.5 29.7 8.1e-113 377.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX80378.1 - 4.2e-22 78.3 56.5 4.1e-18 65.2 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX80378.1 - 1.3e-08 33.7 28.1 1.1e-05 24.0 7.3 3.6 3 1 0 3 3 3 3 MFS/sugar transport protein Meth_synt_2 PF01717.13 KXX80379.1 - 2.3e-17 63.0 0.0 3.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KXX80379.1 - 4.9e-06 26.0 0.0 0.031 13.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Gelsolin PF00626.17 KXX80380.1 - 2.1e-25 88.1 0.0 2e-07 30.5 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat Abhydrolase_6 PF12697.2 KXX80381.1 - 2.7e-29 102.6 0.0 3.1e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX80381.1 - 4.2e-14 52.5 0.1 5.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX80381.1 - 0.013 15.3 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 KXX80381.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KXX80381.1 - 0.027 13.8 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KXX80381.1 - 0.076 12.2 0.0 0.54 9.4 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KXX80382.1 - 4.4e-20 71.4 0.0 1e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX80382.1 - 9.3e-18 64.6 0.0 3.3e-16 59.5 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX80382.1 - 5.4e-11 42.8 0.3 1.1e-10 41.8 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX80382.1 - 0.0023 17.7 0.0 0.03 14.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S41 PF03572.13 KXX80383.1 - 1.8e-06 27.5 0.0 5.3e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 BNR_2 PF13088.1 KXX80384.1 - 6.8e-05 22.2 0.6 0.02 14.2 0.1 2.4 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KXX80384.1 - 0.71 9.9 10.5 4.3 7.5 0.8 3.8 3 0 0 3 3 3 0 BNR/Asp-box repeat TILa PF12714.2 KXX80385.1 - 0.16 11.7 0.2 0.16 11.7 0.2 3.8 3 1 1 4 4 4 0 TILa domain Adaptin_N PF01602.15 KXX80386.1 - 5.3e-150 500.2 4.6 7.5e-150 499.7 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KXX80386.1 - 1.2e-26 93.6 0.7 7.6e-26 91.0 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KXX80386.1 - 1e-17 64.1 0.1 4.6e-07 30.0 0.0 5.4 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KXX80386.1 - 1.6e-11 43.2 4.8 0.0097 15.9 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KXX80386.1 - 0.0001 22.6 3.0 1.9 9.0 0.0 6.0 6 1 0 6 6 6 1 HEAT-like repeat Arm PF00514.18 KXX80386.1 - 0.00064 19.4 1.5 3.5 7.5 0.0 5.6 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KXX80386.1 - 0.017 14.8 0.0 0.36 10.6 0.0 2.8 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KXX80386.1 - 0.026 13.9 0.2 2.2 7.5 0.0 3.5 3 1 1 4 4 4 0 CLASP N terminal AF0941-like PF14591.1 KXX80386.1 - 0.094 12.7 2.3 0.31 11.1 1.6 1.9 1 0 0 1 1 1 0 AF0941-like Ipi1_N PF12333.3 KXX80386.1 - 0.12 12.2 1.8 24 4.9 0.0 4.0 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Ribosomal_60s PF00428.14 KXX80387.1 - 0.0022 18.3 7.3 0.0022 18.3 5.1 4.2 5 0 0 5 5 5 2 60s Acidic ribosomal protein PBP1_TM PF14812.1 KXX80387.1 - 0.013 15.8 3.9 0.013 15.8 2.7 4.2 3 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lipocalin_5 PF13924.1 KXX80388.1 - 3.1e-19 69.0 0.0 3.5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain LVIVD PF08309.6 KXX80389.1 - 1.7e-09 36.5 3.9 0.039 12.9 0.0 4.4 4 0 0 4 4 4 4 LVIVD repeat NmrA PF05368.8 KXX80390.1 - 1.3e-12 47.4 0.0 1.4e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX80390.1 - 0.0025 17.8 0.7 0.014 15.3 0.2 2.2 2 1 0 2 2 2 1 NADH(P)-binding AflR PF08493.5 KXX80391.1 - 2e-07 30.3 0.0 3.6e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Aflatoxin regulatory protein Asparaginase_2 PF01112.13 KXX80392.1 - 2.5e-85 286.0 0.2 3.2e-85 285.6 0.1 1.0 1 0 0 1 1 1 1 Asparaginase DUF2083 PF09856.4 KXX80392.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Cerato-platanin PF07249.7 KXX80393.1 - 5.9e-07 29.4 0.1 1.3e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Cerato-platanin p450 PF00067.17 KXX80394.1 - 2.3e-76 257.2 0.0 2.8e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.16 KXX80395.1 - 1.1e-198 660.5 0.0 1.3e-198 660.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KXX80395.1 - 0.097 12.1 0.0 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain ChiC PF06483.6 KXX80396.1 - 0.12 12.1 0.0 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Chitinase C CARDB PF07705.6 KXX80397.1 - 0.024 14.6 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 CARDB DUF2341 PF10102.4 KXX80397.1 - 0.071 13.2 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) Arylsulfotran_2 PF14269.1 KXX80398.1 - 1.7e-19 70.1 0.1 2.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KXX80398.1 - 0.00024 19.7 0.0 0.00029 19.4 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) p450 PF00067.17 KXX80400.1 - 5.5e-28 97.6 0.0 3e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 NHL PF01436.16 KXX80401.1 - 4.8e-06 26.2 0.0 0.2 11.7 0.0 4.2 3 1 1 4 4 4 2 NHL repeat SBBP PF06739.6 KXX80401.1 - 7.7e-05 22.3 0.2 0.39 10.5 0.0 3.3 3 0 0 3 3 3 2 Beta-propeller repeat GSDH PF07995.6 KXX80401.1 - 0.00015 20.9 2.7 0.008 15.2 0.8 3.1 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KXX80401.1 - 0.00017 21.0 0.0 0.11 11.8 0.0 3.1 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KXX80401.1 - 0.014 14.4 0.2 2.2 7.3 0.1 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller RCC1_2 PF13540.1 KXX80401.1 - 0.11 12.1 2.4 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Hexapep PF00132.19 KXX80402.1 - 7.7e-14 50.4 11.9 3.7e-11 41.9 3.9 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KXX80402.1 - 9.5e-14 50.6 7.6 5.6e-11 41.8 3.8 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KXX80402.1 - 1e-11 44.6 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Tyrosinase PF00264.15 KXX80403.1 - 6.1e-33 114.8 0.5 8.8e-33 114.3 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_88 PF07470.8 KXX80404.1 - 2.5e-79 266.7 0.1 2.9e-79 266.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 KXX80405.1 - 3.9e-30 104.7 30.1 3.9e-30 104.7 20.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 KXX80406.1 - 6.1e-08 32.8 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX80406.1 - 5.4e-06 26.4 1.1 0.0063 16.7 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX80406.1 - 0.0001 22.1 0.1 0.058 13.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KXX80406.1 - 0.0009 18.9 1.6 0.17 11.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KXX80406.1 - 0.0052 17.2 0.3 0.042 14.3 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) ADP_ribosyl_GH PF03747.9 KXX80407.1 - 5.5e-63 213.4 0.3 7.3e-63 213.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sugar_tr PF00083.19 KXX80408.1 - 4.4e-94 315.6 21.2 5.1e-94 315.3 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX80408.1 - 2e-34 118.8 45.9 1.3e-29 102.9 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX80408.1 - 0.00092 17.5 10.1 0.0034 15.6 2.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) VEFS-Box PF09733.4 KXX80408.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF3881 PF12997.2 KXX80408.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF2207 PF09972.4 KXX80408.1 - 0.63 8.5 3.0 2.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ATP-synt_C PF00137.16 KXX80409.1 - 5.1e-18 64.7 17.5 1.4e-16 60.1 9.1 2.4 2 0 0 2 2 2 2 ATP synthase subunit C MFS_3 PF05977.8 KXX80409.1 - 0.063 11.3 8.3 0.07 11.2 5.8 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Gly-zipper_OmpA PF13436.1 KXX80409.1 - 2.2 7.9 9.1 3.8 7.2 6.3 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain p450 PF00067.17 KXX80410.1 - 1.8e-37 128.9 0.0 2.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KXX80411.1 - 2.3e-32 112.0 24.1 3.2e-32 111.6 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3341 PF11821.3 KXX80411.1 - 0.32 10.4 2.5 0.26 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF1049 PF06305.6 KXX80411.1 - 5.7 6.4 9.3 4 6.9 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1049) Glyco_hydro_61 PF03443.9 KXX80412.1 - 1.8e-27 96.5 0.0 2.2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alpha_kinase PF02816.13 KXX80413.1 - 1.4e-42 145.5 0.0 1.7e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family DUF4214 PF13946.1 KXX80415.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) DUF2786 PF10979.3 KXX80415.1 - 0.28 10.9 0.3 0.28 10.9 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Snf7 PF03357.16 KXX80416.1 - 2.9e-07 30.0 1.5 5.6e-07 29.0 0.1 1.8 1 1 0 2 2 2 1 Snf7 Aminotran_3 PF00202.16 KXX80417.1 - 9.2e-26 90.4 0.0 2.2e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_3 PF00202.16 KXX80418.1 - 4.9e-13 48.6 0.0 5.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1045 PF06299.7 KXX80419.1 - 0.028 14.0 0.5 0.051 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) NAD_binding_10 PF13460.1 KXX80420.1 - 5.9e-11 42.7 0.0 9.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX80420.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family CarboxypepD_reg PF13620.1 KXX80421.1 - 8.5e-05 22.5 0.1 0.00039 20.4 0.1 2.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Stanniocalcin PF03298.8 KXX80421.1 - 0.00049 19.1 3.4 0.00086 18.3 2.4 1.3 1 0 0 1 1 1 1 Stanniocalcin family Sugar_tr PF00083.19 KXX80422.1 - 3.2e-104 349.0 25.0 3.7e-104 348.8 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX80422.1 - 2.3e-25 89.0 32.7 7.3e-17 61.1 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KXX80422.1 - 0.0014 18.6 2.8 0.16 11.9 0.5 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) PALP PF00291.20 KXX80423.1 - 5.2e-24 85.0 1.4 6.4e-24 84.7 0.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_hydro_61 PF03443.9 KXX80424.1 - 2e-23 83.3 0.0 3.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SPDY PF03771.11 KXX80424.1 - 0.0018 17.7 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF317) Trp_DMAT PF11991.3 KXX80425.1 - 3.4e-77 260.0 0.0 4.5e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.23 KXX80427.1 - 0 1021.6 4.7 1.8e-83 280.2 0.0 4.6 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 KXX80427.1 - 2.7e-192 637.1 0.0 6.7e-48 163.0 0.0 6.1 6 0 0 6 6 6 5 Condensation domain PP-binding PF00550.20 KXX80427.1 - 1.8e-31 108.2 0.4 4.9e-11 42.7 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX80427.1 - 1.4e-14 54.8 0.7 9.6e-05 23.2 0.0 4.5 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain AATase PF07247.7 KXX80427.1 - 1.6 7.2 0.0 16 3.8 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase GH3 PF03321.8 KXX80427.1 - 2.3 6.6 1.9 7 5.0 0.0 2.7 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Condensation PF00668.15 KXX80428.1 - 2.3e-33 115.3 0.0 3.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KXX80428.1 - 9e-13 48.2 0.1 4.2e-10 39.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.23 KXX80428.1 - 2.3e-05 22.9 0.1 3.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_2_C PF02836.12 KXX80429.1 - 5.2e-106 353.8 0.0 7e-106 353.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KXX80429.1 - 2.9e-59 200.3 0.0 4.9e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KXX80429.1 - 2e-53 180.3 0.2 3.6e-53 179.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KXX80429.1 - 1.4e-15 57.7 0.0 2.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.10 KXX80429.1 - 0.0022 17.1 0.2 0.0043 16.2 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase HET PF06985.6 KXX80430.1 - 4e-28 98.3 0.0 6.3e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C2 PF00168.25 KXX80431.1 - 8.9e-15 54.3 0.0 9.9e-13 47.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 KXX80431.1 - 0.00023 21.2 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Glycos_transf_N PF04413.11 KXX80431.1 - 0.0093 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) WD40 PF00400.27 KXX80432.1 - 3.4e-13 48.9 3.8 0.0016 18.2 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat RRM_1 PF00076.17 KXX80433.1 - 6.3e-68 224.3 2.7 7.4e-18 63.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80433.1 - 2.4e-63 210.0 1.0 8.3e-15 54.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80433.1 - 4e-30 103.4 0.2 3.9e-07 29.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX80433.1 - 7.1e-06 25.7 0.0 0.27 11.0 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KXX80433.1 - 0.00024 20.7 0.3 1.4 8.6 0.0 4.3 4 1 0 4 4 4 1 Limkain b1 RRM_3 PF08777.6 KXX80433.1 - 0.0036 17.1 1.3 0.87 9.4 0.0 4.2 5 1 0 5 5 5 1 RNA binding motif Nup35_RRM PF05172.8 KXX80433.1 - 0.057 13.1 0.0 1.1 9.0 0.0 3.0 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif DUF2839 PF10999.3 KXX80433.1 - 0.34 10.9 1.2 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Dus PF01207.12 KXX80434.1 - 2.9e-37 128.1 0.0 3.6e-28 98.2 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KXX80434.1 - 0.032 13.9 4.2 2.5 7.8 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pro_isomerase PF00160.16 KXX80435.1 - 9.4e-49 165.5 0.3 1.1e-48 165.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KXX80435.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Dynein_light PF01221.13 KXX80436.1 - 3.6e-40 135.8 1.6 4.1e-40 135.6 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peroxin-13_N PF04088.8 KXX80439.1 - 1.3e-56 190.9 0.0 2e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KXX80439.1 - 2.9e-08 33.0 0.0 7.4e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX80439.1 - 5e-06 25.8 0.1 1.2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX80439.1 - 1.4e-05 24.5 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Med3 PF11593.3 KXX80439.1 - 0.45 9.7 6.1 2.6 7.2 0.5 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal WD40 PF00400.27 KXX80440.1 - 2.4e-08 33.5 10.1 0.0042 16.9 0.0 7.8 8 0 0 8 8 8 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KXX80440.1 - 2.1e-06 27.4 0.2 5.2e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 KXX80440.1 - 0.017 15.4 2.3 15 6.0 0.1 4.3 5 0 0 5 5 5 0 PQQ-like domain PQQ PF01011.16 KXX80440.1 - 0.035 13.6 0.2 0.92 9.1 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 KXX80440.1 - 0.33 9.1 0.0 2.9 6.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) Treacle PF03546.9 KXX80440.1 - 0.9 8.2 4.4 0.42 9.3 0.3 2.0 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle NAPRTase PF04095.11 KXX80441.1 - 1.2e-50 172.0 0.1 1e-49 169.0 0.1 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Transglut_core PF01841.14 KXX80442.1 - 4.5e-15 55.8 1.1 1e-14 54.6 0.7 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 KXX80442.1 - 1.3e-14 53.7 5.4 2.4e-14 52.9 3.8 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain ATP-synt_G PF04718.10 KXX80443.1 - 1.4e-27 96.3 1.2 9.1e-27 93.7 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Alpha_adaptin_C PF02296.11 KXX80443.1 - 0.043 13.7 0.1 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Tet_JBP PF12851.2 KXX80443.1 - 0.096 11.9 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily EspB PF05802.6 KXX80443.1 - 0.55 9.1 11.2 7.4 5.4 6.4 2.0 1 1 1 2 2 2 0 Enterobacterial EspB protein ADH_N PF08240.7 KXX80444.1 - 4.6e-26 90.7 2.7 9.4e-26 89.7 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX80444.1 - 1.9e-16 59.8 0.1 2.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KXX80444.1 - 0.0039 16.8 0.1 0.06 13.0 0.0 2.4 2 0 0 2 2 2 1 S1-like Ceramidase PF05875.7 KXX80445.1 - 2.7e-29 102.1 12.5 6.7e-14 51.6 2.5 3.1 1 1 1 2 2 2 2 Ceramidase MerC PF03203.9 KXX80445.1 - 0.017 15.4 1.4 0.14 12.5 0.9 2.3 1 1 0 1 1 1 0 MerC mercury resistance protein Leader_Trp PF08255.6 KXX80445.1 - 0.076 12.6 3.2 0.29 10.8 2.2 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide DUF2953 PF11167.3 KXX80445.1 - 0.095 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) DUF805 PF05656.9 KXX80445.1 - 0.33 10.7 3.9 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Methyltransf_23 PF13489.1 KXX80446.1 - 4.6e-13 49.1 0.0 6.9e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80446.1 - 7e-10 39.4 0.0 1.6e-08 35.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80446.1 - 1e-09 38.1 0.0 1.3e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80446.1 - 4.6e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX80446.1 - 4.7e-06 26.9 0.0 2e-05 25.0 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KXX80446.1 - 1.6e-05 24.3 0.0 3.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KXX80446.1 - 0.00022 21.5 0.0 0.001 19.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX80446.1 - 0.0006 18.9 0.0 0.00099 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KXX80446.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KXX80446.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KXX80446.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX80446.1 - 0.12 11.4 0.0 0.32 10.0 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family HIG_1_N PF04588.8 KXX80447.1 - 3.4e-07 29.8 3.9 3.4e-07 29.8 2.7 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Romo1 PF10247.4 KXX80447.1 - 0.072 13.2 2.4 0.14 12.3 1.7 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF202 PF02656.10 KXX80447.1 - 7.6 6.8 8.3 18 5.6 3.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Kelch_4 PF13418.1 KXX80448.1 - 3.8e-43 145.0 18.7 1.6e-09 37.3 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KXX80448.1 - 1.7e-41 139.4 22.4 1.4e-09 37.8 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KXX80448.1 - 1.6e-38 129.9 16.8 3.2e-08 33.0 1.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KXX80448.1 - 2.1e-38 129.6 22.9 4.4e-07 29.7 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KXX80448.1 - 3.5e-35 118.7 15.6 7.8e-07 29.0 0.1 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KXX80448.1 - 1.9e-31 106.6 17.2 9.5e-09 34.6 0.3 6.5 6 0 0 6 6 6 6 Kelch motif TEA PF01285.13 KXX80450.1 - 2.4e-12 46.7 0.6 5.3e-11 42.3 0.0 2.6 2 0 0 2 2 2 2 TEA/ATTS domain family HSP70 PF00012.15 KXX80451.1 - 1.8e-252 838.6 4.7 2e-252 838.4 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX80451.1 - 7.3e-21 74.1 1.0 6e-20 71.0 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KXX80451.1 - 9.2e-05 21.4 0.4 0.0015 17.4 0.3 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 KXX80451.1 - 0.052 12.4 0.1 0.19 10.5 0.0 2.0 1 1 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 KXX80451.1 - 0.077 12.0 1.9 1.4 7.9 0.0 2.9 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KXX80451.1 - 0.8 9.5 8.6 13 5.6 1.3 3.8 2 2 0 2 2 2 0 Cell division protein FtsA zf-H2C2_2 PF13465.1 KXX80452.1 - 3.9e-05 23.7 6.0 0.003 17.7 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KXX80452.1 - 0.027 14.6 0.2 0.027 14.6 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KXX80452.1 - 0.029 14.2 0.8 0.029 14.2 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KXX80452.1 - 0.064 13.6 0.4 0.064 13.6 0.3 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX80452.1 - 1.6 9.2 21.7 0.16 12.4 1.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Kelch_4 PF13418.1 KXX80453.1 - 5.4e-27 93.3 7.6 6.4e-09 35.4 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KXX80453.1 - 4.8e-24 83.8 1.5 6.2e-07 29.2 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KXX80453.1 - 1.1e-22 79.1 1.7 0.00026 21.0 0.1 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KXX80453.1 - 1.2e-20 72.7 0.2 6.5e-05 22.3 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 KXX80453.1 - 2e-18 66.0 6.7 8.6e-07 28.9 0.0 6.4 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX80453.1 - 2.5e-17 61.8 2.4 0.0012 18.5 0.0 4.9 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KXX80453.1 - 1.4e-09 37.8 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 KXX80453.1 - 0.27 10.3 0.0 0.68 9.0 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity WD40 PF00400.27 KXX80454.1 - 8e-25 85.7 18.7 1.7e-06 27.6 0.1 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KXX80454.1 - 1.6e-06 27.9 0.3 8.1e-05 22.4 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KXX80454.1 - 0.024 14.1 0.0 0.55 9.7 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 KXX80454.1 - 0.095 12.4 2.0 2.6 7.7 0.1 3.4 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term TFIIA PF03153.8 KXX80455.1 - 1.1e-84 285.5 8.2 1.3e-84 285.3 5.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KXX80455.1 - 0.75 9.4 5.9 1.3 8.7 4.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein p450 PF00067.17 KXX80456.1 - 4.4e-70 236.4 0.0 5.5e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YjgP_YjgQ PF03739.9 KXX80456.1 - 0.04 12.6 1.8 0.11 11.1 0.9 1.8 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Kinesin PF00225.18 KXX80458.1 - 2.9e-97 325.3 1.0 5.5e-97 324.4 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Spore_coat_CotO PF14153.1 KXX80458.1 - 1.3 8.4 8.8 2.8 7.3 6.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.1 KXX80458.1 - 5.4 5.8 15.8 4.1 6.2 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Stk19 PF10494.4 KXX80459.1 - 8.3e-50 169.5 0.0 1.1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF2984 PF11203.3 KXX80459.1 - 0.094 12.8 1.9 2.6 8.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) DIOX_N PF14226.1 KXX80460.1 - 1.7e-12 47.8 0.0 1.8e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal zf-met2 PF12907.2 KXX80461.1 - 1.7e-16 59.8 3.5 2.6e-16 59.3 2.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KXX80461.1 - 0.00035 21.2 9.0 0.00071 20.2 6.2 1.5 1 0 0 1 1 1 1 4F5 protein family HypA PF01155.14 KXX80461.1 - 0.076 12.7 0.3 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF1479 PF07350.7 KXX80462.1 - 1.9e-108 362.6 0.0 7.9e-86 288.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) HHH PF00633.18 KXX80462.1 - 0.0071 16.0 0.1 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif PhyH PF05721.8 KXX80462.1 - 0.012 15.6 0.0 0.97 9.4 0.0 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.15 KXX80463.1 - 6e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KXX80463.1 - 2.3e-09 37.7 0.0 1.9e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal RNA_pol_N PF01194.12 KXX80464.1 - 2.3e-17 62.7 0.1 3.2e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 KXX80465.1 - 2.5e-07 30.3 5.1 0.00069 19.4 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat MRJP PF03022.11 KXX80465.1 - 0.27 10.3 0.5 5.3 6.1 0.0 2.8 3 0 0 3 3 3 0 Major royal jelly protein Methyltransf_16 PF10294.4 KXX80466.1 - 3.8e-21 75.3 0.0 7.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KXX80466.1 - 3e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80466.1 - 0.044 14.3 0.0 0.15 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KXX80466.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF416 PF04222.7 KXX80467.1 - 0.052 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Bap31 PF05529.7 KXX80468.1 - 5.4e-68 228.2 3.0 6.2e-68 228.0 2.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 KXX80468.1 - 0.049 13.0 4.8 0.066 12.6 3.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Uds1 PF15456.1 KXX80468.1 - 0.17 11.8 2.0 0.19 11.7 0.7 1.5 1 1 0 1 1 1 0 Up-regulated During Septation MpPF26 PF07666.6 KXX80468.1 - 2.3 8.1 8.6 1.3 8.8 4.1 1.9 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF465 PF04325.8 KXX80468.1 - 2.7 7.7 8.9 0.24 11.1 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Anoctamin PF04547.7 KXX80468.1 - 4.2 5.9 7.3 4.7 5.7 4.9 1.4 1 1 0 1 1 1 0 Calcium-activated chloride channel Sec8_exocyst PF04048.9 KXX80470.1 - 8e-50 168.1 0.5 1.6e-49 167.1 0.3 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KXX80470.1 - 2.2e-10 39.9 2.2 4e-10 39.0 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) SMI1_KNR4 PF09346.5 KXX80471.1 - 1.6e-36 125.1 0.0 2.4e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Chorion_2 PF03964.10 KXX80471.1 - 0.088 13.3 0.2 0.088 13.3 0.1 3.5 3 1 1 4 4 4 0 Chorion family 2 zf-C2H2_4 PF13894.1 KXX80472.1 - 0.1 12.9 13.6 1.1 9.7 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 KXX80472.1 - 0.5 8.8 5.9 1.6 7.1 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 KXX80472.1 - 0.57 10.6 12.5 0.4 11.1 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.4 KXX80473.1 - 1.1e-52 179.0 0.0 1.7e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KXX80473.1 - 3e-25 88.7 0.4 6e-25 87.7 0.3 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 Complex1_LYR PF05347.10 KXX80474.1 - 1.7e-06 27.7 0.2 3.3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX80474.1 - 3.8e-05 23.8 0.2 6.1e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KXX80474.1 - 0.0011 19.3 0.1 0.0015 19.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like G10 PF01125.12 KXX80475.1 - 6.7e-61 204.0 3.9 7.5e-61 203.9 2.7 1.0 1 0 0 1 1 1 1 G10 protein SNase PF00565.12 KXX80475.1 - 0.095 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Staphylococcal nuclease homologue RNA_pol_L_2 PF13656.1 KXX80477.1 - 1.4e-28 98.0 0.0 2.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KXX80477.1 - 1.6e-10 39.9 0.0 2.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Spore_coat_CotO PF14153.1 KXX80477.1 - 0.0046 16.4 10.8 0.005 16.3 7.5 1.2 1 0 0 1 1 1 1 Spore coat protein CotO LAT PF15234.1 KXX80477.1 - 0.0063 16.0 7.9 0.009 15.5 5.5 1.2 1 0 0 1 1 1 1 Linker for activation of T-cells DDRGK PF09756.4 KXX80477.1 - 0.015 14.7 10.5 0.021 14.2 7.3 1.3 1 0 0 1 1 1 0 DDRGK domain Tankyrase_bdg_C PF15327.1 KXX80477.1 - 0.052 13.7 8.3 0.079 13.1 5.7 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain RRN3 PF05327.6 KXX80477.1 - 0.057 11.5 6.1 0.052 11.6 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 KXX80477.1 - 0.079 10.9 10.2 0.078 10.9 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.9 KXX80477.1 - 0.25 11.5 33.8 0.44 10.7 23.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family SAPS PF04499.10 KXX80477.1 - 0.26 9.8 5.0 0.22 10.1 3.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 KXX80477.1 - 0.44 8.1 5.2 0.38 8.4 3.6 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 KXX80477.1 - 0.45 8.3 24.4 0.54 8.1 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KXX80477.1 - 0.66 8.3 28.6 0.87 7.9 19.8 1.1 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 KXX80477.1 - 1.1 7.4 5.9 1.2 7.3 4.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RP-C_C PF11800.3 KXX80477.1 - 1.2 8.7 4.4 0.82 9.3 2.1 1.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Pox_Ag35 PF03286.9 KXX80477.1 - 1.2 8.6 11.5 1.9 7.9 8.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Lin-8 PF03353.10 KXX80477.1 - 1.3 8.2 11.2 1.7 7.8 7.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.3 KXX80477.1 - 1.4 7.3 10.1 1.8 7.1 7.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Usp PF00582.21 KXX80477.1 - 2.7 8.1 5.9 6.2 7.0 4.1 1.7 2 0 0 2 2 2 0 Universal stress protein family TRAP_alpha PF03896.11 KXX80477.1 - 3.3 6.6 16.9 4.5 6.1 11.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.7 KXX80477.1 - 5.1 5.7 17.7 6.7 5.3 12.3 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DUF1510 PF07423.6 KXX80477.1 - 5.3 6.3 24.4 6.5 6.0 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KXX80477.1 - 5.7 6.6 11.5 7.5 6.2 7.9 1.2 1 0 0 1 1 1 0 DDHD domain Retinal PF15449.1 KXX80477.1 - 6.1 4.3 12.6 6.8 4.2 8.8 1.0 1 0 0 1 1 1 0 Retinal protein SDA1 PF05285.7 KXX80477.1 - 6.3 5.9 25.2 8 5.6 17.4 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.8 KXX80477.1 - 8.8 4.9 21.4 13 4.3 14.8 1.3 1 0 0 1 1 1 0 Paf1 SprA-related PF12118.3 KXX80477.1 - 9.9 5.3 16.0 13 5.0 11.1 1.1 1 0 0 1 1 1 0 SprA-related family UPF0220 PF05255.6 KXX80478.1 - 1.8e-52 176.9 2.4 2.1e-52 176.7 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DNA_pol_A PF00476.15 KXX80480.1 - 1.2e-100 336.7 0.0 2e-100 336.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A MORN_2 PF07661.8 KXX80480.1 - 0.91 9.7 4.9 5.6 7.3 0.3 3.3 3 0 0 3 3 3 0 MORN repeat variant CH PF00307.26 KXX80481.1 - 5.9e-10 39.1 0.0 9.1e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 KXX80482.1 - 6e-07 29.8 5.7 7.2e-07 29.6 1.0 2.8 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Suf PF05843.9 KXX80483.1 - 0.08 12.6 2.4 0.15 11.7 1.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 KXX80483.1 - 0.24 9.5 12.7 0.34 9.0 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 KXX80483.1 - 0.34 9.8 1.7 0.59 9.0 1.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ABC2_membrane PF01061.19 KXX80484.1 - 1.7e-23 82.9 27.4 2.4e-23 82.4 19.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KXX80484.1 - 2.5e-22 79.6 0.1 4.3e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KXX80484.1 - 3.5e-06 27.1 0.0 2.5e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KXX80484.1 - 4.3e-05 22.7 0.1 8.2e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX80484.1 - 6.9e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX80484.1 - 0.00043 20.3 0.3 0.00076 19.5 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KXX80484.1 - 0.0025 17.8 1.0 0.0066 16.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX80484.1 - 0.0026 18.5 0.0 0.0062 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KXX80484.1 - 0.0027 16.6 0.7 0.0036 16.2 0.1 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 KXX80484.1 - 0.0035 16.8 0.2 0.0065 15.9 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KXX80484.1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KXX80484.1 - 0.0073 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KXX80484.1 - 0.011 15.9 0.1 0.035 14.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KXX80484.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KXX80484.1 - 0.014 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KXX80484.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KXX80484.1 - 0.018 14.2 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 KXX80484.1 - 0.03 13.7 0.1 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KXX80484.1 - 0.031 13.1 0.0 0.078 11.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.1 KXX80484.1 - 0.039 13.7 0.1 0.12 12.1 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KXX80484.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 KXX80484.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KXX80484.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KXX80484.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KXX80484.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KXX80484.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KXX80484.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KXX80484.1 - 0.15 10.7 0.1 0.25 10.0 0.1 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KXX80484.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KXX80484.1 - 0.21 11.1 1.3 0.27 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain Septin PF00735.13 KXX80484.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Septin Zn_clus PF00172.13 KXX80485.1 - 3.4e-09 36.4 7.3 6.9e-09 35.4 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX80485.1 - 6.8e-06 25.1 0.0 2.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3414 PF11894.3 KXX80486.1 - 0 1463.2 0.0 0 1463.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) zf-C3HC4_3 PF13920.1 KXX80487.1 - 4.8e-11 42.1 6.9 7.3e-11 41.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX80487.1 - 2.4e-09 36.8 9.4 4.4e-09 36.0 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX80487.1 - 4.9e-08 32.8 9.4 8.9e-08 32.0 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX80487.1 - 1.6e-07 30.9 8.6 2.5e-07 30.3 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX80487.1 - 5.4e-07 29.1 9.1 8.9e-07 28.4 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX80487.1 - 0.00023 20.9 2.6 0.00046 19.9 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KXX80487.1 - 0.00057 19.4 5.1 0.001 18.6 3.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KXX80487.1 - 0.0047 16.7 7.7 0.0084 15.9 5.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KXX80487.1 - 0.023 14.4 6.6 0.028 14.1 2.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KXX80487.1 - 0.15 11.6 8.1 1 8.9 5.6 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KXX80487.1 - 0.3 11.2 6.8 0.76 9.9 4.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger SSP160 PF06933.6 KXX80487.1 - 3.4 5.5 16.2 5.6 4.8 11.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 KXX80487.1 - 3.4 7.4 11.4 7.4 6.3 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WHIM1 PF15612.1 KXX80488.1 - 0.00074 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 KXX80488.1 - 2.6 5.8 13.7 3.7 5.3 9.5 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 KXX80488.1 - 9.1 5.8 20.9 0.27 10.8 6.1 2.7 2 0 0 2 2 2 0 YL1 nuclear protein Transglut_core PF01841.14 KXX80489.1 - 6e-12 45.7 0.2 1.4e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KXX80489.1 - 1.8e-08 33.7 0.1 4e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX80489.1 - 2.8e-05 23.3 3.2 3e-05 23.3 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KXX80489.1 - 5.9e-05 22.5 0.2 0.00016 21.1 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain CCDC32 PF14989.1 KXX80489.1 - 0.14 11.9 0.5 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 ABC_tran PF00005.22 KXX80490.1 - 4.6e-15 56.1 0.0 9.8e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX80490.1 - 1e-09 38.8 0.1 0.00041 20.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KXX80490.1 - 0.00013 21.1 0.0 0.27 10.2 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 KXX80490.1 - 0.00021 21.3 0.2 0.00049 20.1 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KXX80490.1 - 0.00053 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 KXX80490.1 - 0.00057 17.3 0.2 0.00074 17.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.14 KXX80490.1 - 0.0013 17.9 0.0 0.73 9.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KXX80490.1 - 0.0025 17.2 0.4 0.0062 15.9 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KXX80490.1 - 0.0079 16.3 0.1 0.061 13.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KXX80490.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KXX80490.1 - 0.013 16.3 0.6 0.029 15.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KXX80490.1 - 0.014 15.7 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KXX80490.1 - 0.02 15.0 0.1 0.082 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX80490.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KXX80490.1 - 0.021 14.7 1.0 0.034 14.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KXX80490.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KXX80490.1 - 0.068 13.0 0.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KXX80490.1 - 0.071 13.0 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KXX80490.1 - 0.072 12.5 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KXX80490.1 - 0.12 11.8 0.1 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 KXX80490.1 - 0.14 11.3 0.4 0.24 10.6 0.2 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.7 KXX80490.1 - 0.15 11.7 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 KXX80490.1 - 0.17 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KXX80490.1 - 0.22 10.9 0.3 0.35 10.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RAI1 PF08652.6 KXX80491.1 - 4.1e-29 100.1 0.0 1.4e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Corona_nucleoca PF00937.13 KXX80491.1 - 0.093 11.6 9.4 0.14 11.1 6.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Trypan_PARP PF05887.6 KXX80491.1 - 0.14 11.9 4.3 0.26 11.0 3.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1509 PF07420.6 KXX80491.1 - 0.26 10.5 11.3 0.44 9.7 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Pap_E4 PF02711.9 KXX80491.1 - 3 8.7 10.9 5.8 7.8 7.5 1.4 1 0 0 1 1 1 0 E4 protein Pkinase PF00069.20 KXX80492.1 - 6e-68 228.8 0.0 8.2e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80492.1 - 2.4e-47 161.2 0.0 3.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX80492.1 - 5.8e-05 22.2 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Chorion_2 PF03964.10 KXX80492.1 - 0.22 12.0 4.8 0.13 12.8 0.9 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF3384 PF11864.3 KXX80493.1 - 5.8e-114 381.0 0.0 1.1e-113 380.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KXX80493.1 - 3.1e-54 183.2 0.0 6.1e-54 182.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KXX80493.1 - 8.2e-33 113.9 1.8 6.1e-30 104.4 0.1 2.6 2 0 0 2 2 2 2 Tuberin CAS_CSE1 PF03378.10 KXX80494.1 - 4.3e-175 582.2 0.0 9.9e-175 581.0 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KXX80494.1 - 6e-151 502.1 2.3 4.5e-150 499.3 2.5 1.8 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 KXX80494.1 - 1.8e-11 43.7 0.0 5.7e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 KXX80494.1 - 0.0049 17.1 0.2 0.064 13.5 0.0 2.8 3 0 0 3 3 3 1 HEAT repeats Xpo1 PF08389.7 KXX80494.1 - 0.015 15.2 0.7 1.3 8.8 0.0 3.5 3 1 0 3 3 3 0 Exportin 1-like protein CENP-I PF07778.6 KXX80495.1 - 1.5e-123 412.7 0.0 2.3e-123 412.0 0.0 1.2 1 0 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.19 KXX80496.1 - 4.8e-06 26.5 0.0 0.00044 20.2 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX80496.1 - 1.4e-05 25.2 0.0 3.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX80496.1 - 0.0031 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KXX80496.1 - 0.17 11.5 0.1 0.45 10.0 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PI3_PI4_kinase PF00454.22 KXX80497.1 - 4.5e-44 150.6 0.0 9.2e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KXX80497.1 - 5.5e-39 133.3 0.1 2.4e-38 131.3 0.0 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 KXX80497.1 - 5.1e-25 88.2 5.9 1.1e-24 87.1 4.1 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 KXX80497.1 - 4.1e-11 42.1 0.1 1e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 FATC domain SNF5 PF04855.7 KXX80498.1 - 2.8e-74 249.6 0.1 4.1e-74 249.1 0.1 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PAT1 PF09770.4 KXX80498.1 - 3.8 5.6 8.9 7.1 4.7 6.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M24 PF00557.19 KXX80499.1 - 9.4e-10 38.4 0.0 1.5e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Orbi_NS3 PF01616.11 KXX80499.1 - 0.2 10.6 1.8 0.46 9.4 0.7 1.9 2 0 0 2 2 2 0 Orbivirus NS3 PBP1_TM PF14812.1 KXX80499.1 - 1.9 8.8 9.2 4.9 7.5 6.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.3 KXX80499.1 - 2.3 8.0 12.6 3 7.7 7.5 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.14 KXX80499.1 - 5 7.6 23.3 0.4 11.1 8.3 3.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein FAM176 PF14851.1 KXX80499.1 - 5.5 6.6 6.6 9.5 5.8 4.6 1.4 1 0 0 1 1 1 0 FAM176 family PHD PF00628.24 KXX80500.1 - 5.9e-16 57.8 18.5 2.4e-09 36.7 6.2 2.4 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 KXX80500.1 - 0.0026 17.4 1.0 0.0026 17.4 0.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 KXX80500.1 - 0.012 14.9 9.1 0.04 13.1 1.3 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 KXX80500.1 - 0.019 15.0 7.0 0.11 12.7 1.5 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_3 PF13922.1 KXX80500.1 - 1.5 9.1 7.1 0.27 11.4 0.3 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx C1_1 PF00130.17 KXX80500.1 - 1.8 8.3 14.3 1.5 8.5 1.4 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PDT PF00800.13 KXX80501.1 - 6.6e-57 191.9 0.0 8.7e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KXX80501.1 - 0.0015 17.9 0.0 0.0039 16.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.10 KXX80502.1 - 1.2e-46 158.3 0.2 2.3e-46 157.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KXX80502.1 - 1.3e-40 138.1 0.7 2.6e-40 137.2 0.5 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KXX80502.1 - 6.7e-29 100.1 0.0 1.4e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Flavodoxin_NdrI PF07972.6 KXX80502.1 - 0.014 15.2 0.1 0.15 11.9 0.1 2.5 1 1 0 1 1 1 0 NrdI Flavodoxin like DUF1770 PF08589.5 KXX80503.1 - 4.8e-28 97.7 0.2 6e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ribosomal_L2_C PF03947.13 KXX80504.1 - 2.9e-38 130.6 3.5 4.7e-38 129.9 2.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KXX80504.1 - 7.1e-15 54.7 0.2 1.4e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 KXX80505.1 - 3.2e-66 223.5 0.0 3.9e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KXX80505.1 - 0.044 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Acetyltransf_3 PF13302.1 KXX80506.1 - 1.4e-25 90.1 0.0 1.7e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KXX80506.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX80506.1 - 0.0021 18.0 0.1 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family COPIIcoated_ERV PF07970.7 KXX80507.1 - 3.4e-70 236.1 0.0 1.6e-68 230.6 0.0 2.2 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KXX80507.1 - 7.4e-36 122.0 0.0 1.6e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2321 PF10083.4 KXX80507.1 - 0.18 11.2 0.9 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Per1 PF04080.8 KXX80509.1 - 2.6e-106 354.9 7.7 3.4e-106 354.5 5.3 1.1 1 0 0 1 1 1 1 Per1-like ER_lumen_recept PF00810.13 KXX80511.1 - 8.9e-40 136.5 9.3 1.3e-39 136.0 6.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2227 PF09988.4 KXX80511.1 - 0.017 14.7 1.1 0.037 13.6 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PQ-loop PF04193.9 KXX80511.1 - 0.065 12.8 0.0 0.065 12.8 0.0 3.3 4 0 0 4 4 4 0 PQ loop repeat Sel1 PF08238.7 KXX80512.1 - 8.9e-15 54.7 8.0 0.0004 20.9 0.0 4.3 4 0 0 4 4 4 3 Sel1 repeat Proteasome PF00227.21 KXX80513.1 - 2.1e-45 154.3 0.1 2.7e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KXX80513.1 - 2e-13 49.3 0.5 4.4e-13 48.2 0.4 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Orbi_NS3 PF01616.11 KXX80514.1 - 0.27 10.1 4.5 0.6 9.0 3.1 1.5 1 0 0 1 1 1 0 Orbivirus NS3 Cmc1 PF08583.5 KXX80515.1 - 0.00085 19.0 0.7 0.0047 16.6 0.5 2.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Med15 PF09606.5 KXX80515.1 - 0.0044 15.3 23.6 0.0056 14.9 16.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KXX80515.1 - 0.0058 14.9 23.1 0.01 14.1 16.0 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 KXX80515.1 - 0.015 15.3 13.6 0.026 14.5 9.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gag_spuma PF03276.9 KXX80515.1 - 0.16 10.2 17.6 0.22 9.7 12.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 KXX80515.1 - 0.25 11.2 18.9 0.0084 16.0 8.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 KXX80515.1 - 4.2 7.0 19.8 0.97 9.1 11.5 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AMPKBI PF04739.10 KXX80515.1 - 5.6 6.8 9.4 12 5.8 6.5 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Band_3_cyto PF07565.8 KXX80515.1 - 9.8 5.6 10.3 0.73 9.2 3.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain ATP_sub_h PF10775.4 KXX80516.1 - 5.2e-25 86.9 0.5 8.2e-25 86.3 0.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KXX80516.1 - 0.055 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DOMON PF03351.12 KXX80517.1 - 5e-08 32.9 0.2 2.3e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 KXX80517.1 - 0.00098 18.6 5.6 0.00098 18.6 3.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) ABC_tran PF00005.22 KXX80518.1 - 0.00035 20.8 0.0 0.0011 19.2 0.0 2.1 1 1 0 1 1 1 1 ABC transporter Prok-RING_1 PF14446.1 KXX80518.1 - 0.00094 18.8 4.1 0.00094 18.8 2.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 MMR_HSR1 PF01926.18 KXX80518.1 - 0.0034 17.3 0.0 0.0089 15.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KXX80518.1 - 0.0072 15.4 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 KXX80518.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KXX80518.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX80518.1 - 0.047 13.6 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 KXX80518.1 - 0.048 13.6 0.1 0.2 11.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KXX80518.1 - 0.057 13.7 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KXX80518.1 - 0.093 12.4 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KXX80518.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-B_box PF00643.19 KXX80518.1 - 0.46 10.4 2.7 1.4 8.8 1.8 1.8 1 1 0 1 1 1 0 B-box zinc finger RNA_pol_Rpb2_6 PF00562.23 KXX80519.1 - 3.4e-115 384.8 0.0 4.4e-115 384.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KXX80519.1 - 8.8e-31 106.4 0.0 1.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KXX80519.1 - 2.5e-26 92.2 0.0 4.9e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KXX80519.1 - 3e-25 87.7 0.0 7e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KXX80519.1 - 8.9e-24 83.2 0.0 2.1e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 KXX80519.1 - 1.2e-14 54.3 0.0 5.7e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KXX80519.1 - 9.1e-05 22.3 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 KXX80520.1 - 9.1e-43 145.5 0.0 1.1e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KXX80520.1 - 1.1e-19 70.3 0.0 1.3e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX80520.1 - 4.1e-09 36.9 0.0 9.4e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KXX80520.1 - 2.4e-07 30.1 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KXX80520.1 - 5.4e-07 28.6 0.0 1.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 KXX80520.1 - 6.2e-06 25.5 0.0 7.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KXX80520.1 - 1.4e-05 24.9 0.0 2.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KXX80520.1 - 0.00043 19.7 0.0 0.01 15.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KXX80520.1 - 0.016 15.0 0.1 0.14 11.9 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 KXX80520.1 - 0.019 14.2 0.2 0.048 12.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KXX80520.1 - 0.099 12.1 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Patatin PF01734.17 KXX80521.1 - 1.8e-17 63.9 0.0 2.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Corona_S2 PF01601.11 KXX80522.1 - 0.0045 15.1 11.9 0.006 14.7 8.3 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Ribosomal_S9 PF00380.14 KXX80523.1 - 4.3e-38 130.2 0.4 4.9e-38 130.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MeMO_Hyd_G PF02964.11 KXX80523.1 - 0.077 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain NAD_binding_8 PF13450.1 KXX80524.1 - 2.8e-10 40.0 0.1 5.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX80524.1 - 1.5e-07 30.6 0.9 3e-07 29.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX80524.1 - 6.8e-07 28.5 0.6 1.7e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KXX80524.1 - 2.7e-05 23.4 2.6 4.2e-05 22.8 1.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX80524.1 - 4.9e-05 23.4 0.0 0.00072 19.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX80524.1 - 5e-05 21.9 0.4 7.7e-05 21.3 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KXX80524.1 - 0.0003 19.9 0.7 0.0012 17.9 0.5 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KXX80524.1 - 0.00033 21.0 0.1 0.00062 20.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX80524.1 - 0.00042 19.4 0.5 0.00068 18.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX80524.1 - 0.00078 19.3 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 KXX80524.1 - 0.016 14.6 0.2 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 KXX80524.1 - 0.03 13.2 0.5 0.041 12.7 0.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KXX80524.1 - 0.047 12.5 0.1 0.068 12.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KXX80524.1 - 0.1 11.5 0.0 3.7 6.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KXX80524.1 - 0.14 11.7 1.2 0.26 10.9 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ppx-GppA PF02541.11 KXX80526.1 - 9.7e-28 97.1 0.0 5.2e-26 91.4 0.0 2.2 1 1 0 1 1 1 1 Ppx/GppA phosphatase family DUF3546 PF12066.3 KXX80528.1 - 7.2e-28 96.8 0.8 7.2e-28 96.8 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KXX80528.1 - 2.8e-23 81.2 0.0 7.2e-23 79.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KXX80528.1 - 3.8e-13 50.1 1.9 9.7e-13 48.7 1.3 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DEAD PF00270.24 KXX80529.1 - 9.1e-42 142.4 0.0 1.5e-40 138.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX80529.1 - 1.4e-25 88.9 0.0 3.3e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX80529.1 - 0.0097 15.7 0.0 0.056 13.2 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2986 PF11661.3 KXX80529.1 - 0.022 15.0 3.3 0.022 15.0 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) DUF3334 PF11813.3 KXX80529.1 - 0.051 13.1 3.8 0.052 13.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3334) CMS1 PF14617.1 KXX80529.1 - 1.1 8.2 0.0 1.1 8.2 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.24 KXX80530.1 - 9.8e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX80530.1 - 4.7e-06 26.7 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KXX80530.1 - 2.2e-05 24.1 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KXX80530.1 - 0.00023 21.1 0.0 0.00071 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KXX80530.1 - 0.00028 20.9 0.1 0.0013 18.7 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 KXX80530.1 - 0.0026 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KXX80530.1 - 0.0045 17.7 0.1 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KXX80530.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX80530.1 - 0.0096 15.6 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KXX80530.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KXX80530.1 - 0.023 14.6 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KXX80530.1 - 0.031 13.8 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KXX80530.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX80530.1 - 0.043 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KXX80530.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KXX80530.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KXX80530.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KXX80530.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KXX80530.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KXX80530.1 - 0.13 11.9 0.3 11 5.6 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Cpn60_TCP1 PF00118.19 KXX80531.1 - 9.2e-139 463.1 14.0 1.2e-138 462.8 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KXX80531.1 - 0.009 15.4 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 Phage Tail Protein X DUF3924 PF13062.1 KXX80531.1 - 0.12 12.2 0.3 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) RRM_1 PF00076.17 KXX80532.1 - 2.4e-18 65.5 0.2 4.7e-18 64.5 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80532.1 - 7.1e-13 48.3 0.0 1.4e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80532.1 - 4e-09 36.1 0.1 6.5e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Poty_PP PF08440.5 KXX80532.1 - 0.091 11.8 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein FliD_N PF02465.13 KXX80532.1 - 0.092 13.1 0.8 0.16 12.3 0.6 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Fmp27_WPPW PF10359.4 KXX80532.1 - 0.26 9.6 2.8 0.72 8.1 1.0 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4546 PF15079.1 KXX80533.1 - 0.18 10.9 4.3 0.32 10.1 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) zf-C3HC4 PF00097.20 KXX80533.1 - 0.2 11.3 5.9 0.48 10.1 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cut8_N PF14482.1 KXX80533.1 - 0.75 9.8 11.9 4 7.5 3.1 2.8 2 1 0 2 2 2 0 Cut8 proteasome-binding domain Gastrin PF00918.12 KXX80533.1 - 3 8.7 8.4 0.82 10.4 2.7 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF3661 PF12400.3 KXX80535.1 - 3e-30 104.9 8.0 2.8e-23 82.4 2.4 2.3 2 0 0 2 2 2 2 Vaculolar membrane protein Plant_vir_prot PF01307.12 KXX80535.1 - 0.017 14.8 0.1 0.076 12.7 0.0 2.2 2 1 0 2 2 2 0 Plant viral movement protein Pkinase PF00069.20 KXX80536.1 - 1.2e-70 237.6 0.0 1.7e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80536.1 - 5.3e-31 107.6 0.0 7.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KXX80536.1 - 2.3e-14 53.6 1.5 8.7e-14 51.7 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KXX80536.1 - 4.3e-09 35.7 0.0 7.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KXX80536.1 - 6.9e-05 22.6 0.0 0.00025 20.8 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 KXX80536.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KXX80536.1 - 0.049 12.9 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KXX80536.1 - 0.051 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX80536.1 - 0.082 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.2 KXX80538.1 - 3.4e-05 24.2 6.1 3.4e-05 24.2 4.3 4.0 4 1 0 4 4 4 1 SUZ domain ARGLU PF15346.1 KXX80538.1 - 0.43 10.3 16.0 0.23 11.2 6.4 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 API5 PF05918.6 KXX80538.1 - 2.2 6.6 5.6 3 6.2 3.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fe_hyd_lg_C PF02906.9 KXX80539.1 - 2e-60 204.4 0.0 4.6e-60 203.3 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF3606 PF12244.3 KXX80539.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) zf-H2C2_2 PF13465.1 KXX80541.1 - 1.2e-07 31.7 8.4 3.4e-06 27.0 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX80541.1 - 1.1e-05 25.4 3.2 0.00058 19.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX80541.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KXX80541.1 - 0.17 12.0 2.3 4.2 7.6 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.1 KXX80542.1 - 2.3e-12 45.6 4.6 0.16 12.1 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KXX80542.1 - 1.4e-10 40.5 7.0 0.00043 19.8 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KXX80542.1 - 8.4e-05 22.0 7.9 6.2 7.2 0.0 5.9 6 1 1 7 7 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KXX80542.1 - 0.00026 20.6 3.3 22 5.8 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 KXX80542.1 - 0.0013 18.4 12.3 1.1 9.0 0.1 4.8 3 2 1 4 4 4 3 Leucine rich repeat SDA1 PF05285.7 KXX80542.1 - 0.25 10.5 19.3 0.33 10.1 13.4 1.2 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 KXX80542.1 - 1.4 8.4 18.4 3 7.3 12.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin SprA-related PF12118.3 KXX80542.1 - 3 7.0 14.5 4.6 6.4 10.0 1.2 1 0 0 1 1 1 0 SprA-related family Usp PF00582.21 KXX80542.1 - 4.6 7.4 10.9 10 6.2 7.6 1.6 1 0 0 1 1 1 0 Universal stress protein family RRN3 PF05327.6 KXX80542.1 - 4.8 5.1 13.2 6.6 4.7 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 KXX80542.1 - 6.1 4.9 17.6 8.8 4.4 12.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 KXX80542.1 - 7.2 4.5 15.6 11 3.9 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 KXX80542.1 - 7.5 6.2 13.8 14 5.4 9.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Glyco_hydro_18 PF00704.23 KXX80544.1 - 3.7e-93 312.7 2.6 5.1e-93 312.2 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3153 PF11353.3 KXX80544.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Pol_alpha_B_N PF08418.5 KXX80545.1 - 0.077 12.5 1.0 0.15 11.5 0.7 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 KXX80547.1 - 1.2e-39 136.0 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80547.1 - 3.1e-12 46.1 0.0 3.5e-11 42.6 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KXX80547.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-CCCH PF00642.19 KXX80549.1 - 0.0083 15.7 2.5 0.016 14.8 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KXX80549.1 - 0.017 15.1 2.9 0.032 14.2 2.0 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sec1 PF00995.18 KXX80550.1 - 5.2e-151 504.0 0.0 6.1e-151 503.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1351 PF07083.6 KXX80550.1 - 0.026 14.1 0.9 0.84 9.2 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) Chitin_synth_1 PF01644.12 KXX80551.1 - 6e-81 270.0 0.3 8.8e-81 269.4 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KXX80551.1 - 1.5e-32 111.0 0.0 3.2e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KXX80551.1 - 1.2e-22 79.9 2.3 6e-18 64.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KXX80551.1 - 7.9e-08 32.2 7.8 5.1e-07 29.5 5.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX80551.1 - 9.7e-07 28.8 0.0 3.6e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3602 PF12223.3 KXX80552.1 - 1.9e-15 57.0 13.4 1.7e-13 50.7 1.7 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) RRM_1 PF00076.17 KXX80553.1 - 2.5e-38 129.5 0.2 8.6e-18 63.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80553.1 - 1.7e-29 101.6 2.8 4.5e-15 55.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80553.1 - 3.6e-11 42.7 8.0 1.6e-05 24.6 0.0 2.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX80553.1 - 0.00014 21.5 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RabGAP-TBC PF00566.13 KXX80554.1 - 2.5e-48 164.3 0.0 5.7e-48 163.2 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.4 KXX80555.1 - 9e-17 60.0 0.1 5.8e-16 57.4 0.1 2.6 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 KXX80555.1 - 7.4e-07 29.0 9.3 0.00098 19.0 1.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX80555.1 - 0.00019 22.0 2.7 0.00019 22.0 1.8 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX80555.1 - 0.0004 19.9 11.7 0.0011 18.5 1.2 3.3 3 1 0 3 3 3 2 TPR repeat Apc3 PF12895.2 KXX80555.1 - 0.00099 19.2 1.8 0.022 14.9 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 KXX80555.1 - 0.0023 17.6 3.1 0.006 16.3 2.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80555.1 - 0.0036 17.6 1.8 0.0036 17.6 1.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX80555.1 - 0.084 13.1 1.2 5.1 7.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AATF-Che1 PF13339.1 KXX80555.1 - 0.16 12.0 0.1 0.16 12.0 0.1 3.2 1 1 2 4 4 4 0 Apoptosis antagonizing transcription factor TPR_10 PF13374.1 KXX80555.1 - 0.71 9.8 6.4 0.24 11.3 0.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80555.1 - 5.7 7.1 17.1 0.45 10.5 2.5 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Flavoprotein PF02441.14 KXX80556.1 - 1.1e-28 99.4 0.2 1.8e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein Btz PF09405.5 KXX80557.1 - 9.8e-29 100.0 2.8 9.8e-29 100.0 1.9 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 KXX80558.1 - 1.1e-11 44.5 0.2 4e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Pectate_lyase PF03211.8 KXX80558.1 - 0.051 12.9 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase Asp_protease_2 PF13650.1 KXX80558.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Aconitase PF00330.15 KXX80559.1 - 1.8e-153 511.3 0.0 3.9e-153 510.2 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KXX80559.1 - 5.2e-38 130.1 0.0 9e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KXX80559.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Rad52_Rad22 PF04098.10 KXX80560.1 - 6.2e-61 204.6 0.0 8.3e-61 204.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HEAT PF02985.17 KXX80561.1 - 1.1e-10 40.6 0.9 0.02 14.9 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 KXX80561.1 - 1.8e-07 30.5 0.0 3.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80561.1 - 3e-05 23.2 0.0 5.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 KXX80561.1 - 0.00046 20.4 0.3 0.048 13.9 0.0 3.3 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.1 KXX80561.1 - 0.0012 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 KXX80561.1 - 0.0021 17.9 0.0 0.0068 16.2 0.0 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KXX80561.1 - 0.0036 17.7 0.0 0.64 10.5 0.0 3.2 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.15 KXX80561.1 - 0.031 12.5 0.1 0.05 11.9 0.1 1.3 1 0 0 1 1 1 0 Adaptin N terminal region ZZ PF00569.12 KXX80562.1 - 1.3e-18 66.2 56.1 4.8e-06 26.0 4.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Baculo_IE-1 PF05290.6 KXX80562.1 - 0.0057 16.3 0.6 0.0057 16.3 0.4 2.3 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) UPF0052 PF01933.13 KXX80563.1 - 5.6e-53 180.2 0.0 7.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cut8_C PF08559.5 KXX80564.1 - 3e-48 163.2 0.0 4e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KXX80564.1 - 1.3e-18 66.4 1.1 2.8e-18 65.4 0.8 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KXX80564.1 - 2.6e-09 36.9 0.3 5.2e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 Cut8 proteasome-binding domain RRM_1 PF00076.17 KXX80565.1 - 4e-22 77.6 0.1 8.2e-14 50.9 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX80565.1 - 5.6e-20 71.1 0.0 1.5e-09 37.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80565.1 - 4.5e-07 29.6 0.1 0.0015 18.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX80565.1 - 0.0007 19.4 1.8 0.012 15.4 0.0 2.8 2 0 0 2 2 2 1 RNA binding motif Sigma70_ner PF04546.8 KXX80565.1 - 9.9 5.7 10.9 0.81 9.2 2.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region PhyH PF05721.8 KXX80566.1 - 2e-60 204.4 0.0 2.4e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CENP-B_dimeris PF09026.5 KXX80567.1 - 0.0052 16.9 1.2 0.0093 16.1 0.8 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Rho_N PF07498.7 KXX80567.1 - 0.0069 16.1 0.4 0.013 15.2 0.3 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain PBP1_TM PF14812.1 KXX80567.1 - 0.029 14.6 0.5 0.052 13.8 0.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KXX80567.1 - 0.1 12.0 3.4 0.16 11.5 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 KXX80567.1 - 0.28 11.5 6.9 0.61 10.5 4.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.6 KXX80567.1 - 0.48 9.6 7.8 0.74 9.0 5.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PVL_ORF50 PF07768.6 KXX80567.1 - 0.74 9.8 3.7 1.3 9.0 2.5 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Adeno_terminal PF02459.10 KXX80567.1 - 0.79 7.8 4.4 1.1 7.3 3.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Myc_N PF01056.13 KXX80567.1 - 4.3 6.4 8.7 6.5 5.8 6.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.27 KXX80568.1 - 2.4e-48 160.3 16.3 2.1e-11 43.2 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KXX80568.1 - 5.8e-07 28.0 1.8 0.3 9.1 0.1 4.7 4 1 1 5 5 5 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 KXX80568.1 - 0.0079 14.4 0.0 0.019 13.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Nbas_N PF15492.1 KXX80568.1 - 0.071 12.2 0.0 16 4.4 0.0 3.2 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FHA PF00498.21 KXX80569.1 - 5.3e-12 45.6 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain RRN3 PF05327.6 KXX80569.1 - 1.6 6.7 10.0 2.4 6.1 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 KXX80569.1 - 3.2 7.0 11.9 6.5 6.0 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) IFRD PF05004.8 KXX80570.1 - 7.4e-34 117.2 4.3 9.2e-34 116.9 3.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 KXX80570.1 - 0.0048 17.3 0.5 4.2 7.9 0.0 3.8 2 2 2 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 KXX80570.1 - 0.014 15.6 1.4 0.13 12.5 0.5 2.4 1 1 1 2 2 2 0 HEAT repeats Transket_pyr PF02779.19 KXX80571.1 - 0.039 13.4 1.4 0.21 11.0 0.2 2.4 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain AhpC-TSA_2 PF13911.1 KXX80573.1 - 1.4e-18 66.8 0.0 3.8e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KXX80573.1 - 0.017 14.7 0.0 0.049 13.3 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family Gag_spuma PF03276.9 KXX80573.1 - 0.12 10.6 0.0 0.12 10.6 0.0 1.6 2 0 0 2 2 2 0 Spumavirus gag protein UPF1_Zn_bind PF09416.5 KXX80574.1 - 9.3e-72 239.5 5.5 2.5e-71 238.2 1.5 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KXX80574.1 - 4.8e-62 208.9 0.0 1.4e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KXX80574.1 - 5.7e-57 193.0 2.8 9.2e-57 192.3 1.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX80574.1 - 4.9e-14 51.8 0.2 1.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KXX80574.1 - 3.4e-12 46.3 0.4 6.5e-11 42.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KXX80574.1 - 2.9e-07 30.5 0.0 5.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KXX80574.1 - 1.8e-05 24.4 0.1 4.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KXX80574.1 - 3.1e-05 23.6 0.4 0.29 10.6 0.0 3.2 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 KXX80574.1 - 0.00024 20.1 0.2 0.18 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.16 KXX80574.1 - 0.00024 20.4 0.1 0.0059 15.9 0.1 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 KXX80574.1 - 0.00026 20.0 1.2 0.0015 17.5 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KXX80574.1 - 0.0014 18.1 0.2 0.003 17.0 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 KXX80574.1 - 0.0046 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 KXX80574.1 - 0.0074 15.4 0.0 0.028 13.5 0.0 1.9 3 0 0 3 3 2 1 KaiC Ribosomal_S13_N PF08069.7 KXX80574.1 - 0.0089 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 KXX80574.1 - 0.013 15.4 0.1 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KXX80574.1 - 0.037 13.5 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KXX80574.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 KXX80574.1 - 0.097 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KXX80574.1 - 0.1 12.7 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KXX80574.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 KXX80574.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 KXX80574.1 - 0.13 11.6 0.6 0.36 10.2 0.4 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 KXX80574.1 - 0.21 10.8 0.0 0.51 9.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Brix PF04427.13 KXX80575.1 - 6.1e-45 153.2 0.5 7.6e-45 152.9 0.4 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.20 KXX80576.1 - 5.4e-11 42.5 5.4 5.4e-11 42.5 3.7 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KXX80576.1 - 3.6e-07 29.7 6.4 3.6e-07 29.7 4.4 2.2 2 0 0 2 2 2 1 SNARE domain Spc7 PF08317.6 KXX80576.1 - 0.14 10.8 13.5 0.69 8.5 0.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3018 PF11455.3 KXX80576.1 - 0.23 11.4 5.9 0.23 11.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) SlyX PF04102.7 KXX80576.1 - 0.31 11.4 9.5 0.09 13.1 1.7 2.9 2 1 0 2 2 2 0 SlyX Baculo_PEP_C PF04513.7 KXX80576.1 - 2.5 7.9 16.2 1.4 8.7 1.9 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Synaptobrevin PF00957.16 KXX80576.1 - 2.9 7.5 8.1 0.34 10.5 1.5 2.3 2 1 1 3 3 3 0 Synaptobrevin FAA_hydrolase_N PF09298.6 KXX80576.1 - 2.9 7.9 7.2 1.4 8.9 0.6 2.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal Syntaxin_2 PF14523.1 KXX80576.1 - 8.6 6.4 18.1 0.3 11.1 5.9 2.4 2 0 0 2 2 2 0 Syntaxin-like protein TPR_11 PF13414.1 KXX80577.1 - 1e-55 185.2 26.9 2.9e-16 58.8 0.9 6.7 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KXX80577.1 - 5.4e-46 152.3 33.0 2.8e-06 26.7 0.0 11.3 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80577.1 - 1.2e-39 131.0 30.6 2.7e-05 23.7 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.1 KXX80577.1 - 4.8e-28 97.1 11.4 8.4e-07 29.5 0.4 7.0 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KXX80577.1 - 2.1e-26 89.9 12.0 0.0006 19.7 0.4 8.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80577.1 - 2.8e-26 91.2 25.4 4.4e-06 26.5 0.0 7.3 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 KXX80577.1 - 2.5e-14 51.8 27.5 0.0085 15.8 0.1 10.6 10 1 1 11 11 11 5 Tetratricopeptide repeat Apc3 PF12895.2 KXX80577.1 - 6.2e-13 48.6 19.5 0.0013 18.8 0.2 5.4 3 1 3 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KXX80577.1 - 9.5e-13 47.8 11.0 4.7e-05 23.1 0.2 6.8 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80577.1 - 2.4e-12 47.0 22.4 0.00018 21.7 0.7 7.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80577.1 - 9.5e-12 44.4 19.4 0.044 14.4 0.2 10.0 4 3 6 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX80577.1 - 1.9e-10 39.7 25.6 0.14 12.0 0.2 9.5 9 1 1 10 10 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KXX80577.1 - 1.6e-06 27.2 5.9 0.59 9.4 0.0 6.0 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.1 KXX80577.1 - 2.3e-06 26.8 10.7 0.29 10.1 0.6 5.6 3 1 1 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.2 KXX80577.1 - 0.0032 17.3 7.7 7.5 6.3 0.0 5.6 4 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.7 KXX80577.1 - 0.18 12.4 5.1 1.5 9.5 0.1 3.9 3 0 0 3 3 3 0 Sel1 repeat TPR_20 PF14561.1 KXX80577.1 - 0.25 11.4 9.2 9 6.4 0.2 5.0 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KXX80577.1 - 0.58 10.7 26.4 20 5.9 0.3 9.2 10 1 0 10 10 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 KXX80577.1 - 3.7 7.5 17.0 4.6 7.3 0.5 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 KXX80577.1 - 4.5 5.9 26.5 0.69 8.5 1.8 4.5 2 2 0 3 3 2 0 NMDA receptor-regulated protein 1 Aminotran_4 PF01063.14 KXX80578.1 - 7.5e-22 77.9 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Actin PF00022.14 KXX80579.1 - 2e-132 441.3 0.0 2.3e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KXX80579.1 - 0.0043 15.6 0.0 0.92 8.0 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein Methyltransf_23 PF13489.1 KXX80581.1 - 6.2e-20 71.5 0.0 2.3e-19 69.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80581.1 - 1.4e-12 47.4 0.0 1.7e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80581.1 - 1.1e-11 45.0 0.0 2.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80581.1 - 4.5e-11 43.3 0.1 5.1e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX80581.1 - 8e-11 42.2 0.0 5.5e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80581.1 - 5.2e-07 29.9 0.0 1.7e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KXX80581.1 - 6.1e-05 22.2 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KXX80581.1 - 7.7e-05 22.7 0.0 0.00027 20.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX80581.1 - 0.0002 20.7 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KXX80581.1 - 0.00037 19.5 0.0 0.00076 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KXX80581.1 - 0.0014 18.6 0.1 0.0043 17.0 0.0 1.8 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KXX80581.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KXX80581.1 - 0.023 13.7 0.0 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KXX80581.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KXX80582.1 - 4.6e-23 81.6 0.0 7.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dak2 PF02734.12 KXX80582.1 - 0.011 15.4 0.4 0.024 14.2 0.2 1.7 1 1 0 1 1 1 0 DAK2 domain HTH_24 PF13412.1 KXX80582.1 - 0.036 13.4 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KXX80582.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_23 PF13489.1 KXX80582.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain HTH_3 PF01381.17 KXX80582.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix GHMP_kinases_N PF00288.21 KXX80583.1 - 8e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KXX80583.1 - 2.3e-06 27.6 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1996 PF09362.5 KXX80586.1 - 3e-86 288.9 1.6 3.5e-86 288.6 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NAD_binding_2 PF03446.10 KXX80587.1 - 2.2e-32 112.1 0.1 2.6e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KXX80587.1 - 0.00013 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KXX80587.1 - 0.00027 20.6 0.1 0.00044 19.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KXX80587.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KXX80587.1 - 0.041 13.2 0.0 0.18 11.1 0.0 1.8 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Dak1 PF02733.12 KXX80588.1 - 5.6e-112 373.4 0.0 7.8e-112 373.0 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KXX80588.1 - 3.4e-42 144.0 1.7 6e-42 143.2 1.2 1.4 1 0 0 1 1 1 1 DAK2 domain Tic20 PF09685.5 KXX80590.1 - 2.6e-07 30.6 1.3 3.5e-07 30.1 0.9 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF3782 PF12644.2 KXX80590.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) PilM_2 PF11104.3 KXX80591.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; IncA PF04156.9 KXX80594.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 IncA protein DAO PF01266.19 KXX80595.1 - 1.3e-31 109.7 0.0 1.8e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX80595.1 - 2e-10 40.1 0.2 8.8e-08 31.4 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX80595.1 - 1.7e-08 34.7 0.0 0.00017 21.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX80595.1 - 1.5e-07 30.2 0.1 6.8e-06 24.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KXX80595.1 - 7.7e-07 29.1 0.0 0.00064 19.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX80595.1 - 8.8e-06 24.9 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KXX80595.1 - 1.4e-05 24.3 0.0 6.3e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KXX80595.1 - 1.4e-05 24.3 0.0 2.8e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX80595.1 - 1.9e-05 24.5 0.1 5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GDI PF00996.13 KXX80595.1 - 0.00022 19.6 0.0 0.00033 19.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.17 KXX80595.1 - 0.00023 20.1 0.0 0.00073 18.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KXX80595.1 - 0.0086 16.3 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KXX80595.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX80595.1 - 0.068 12.0 0.1 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KXX80595.1 - 0.14 11.0 0.0 8.9 5.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Clr5 PF14420.1 KXX80596.1 - 8.5e-21 73.6 3.4 1.6e-20 72.7 2.4 1.5 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.24 KXX80597.1 - 1.7e-40 138.2 0.0 4.7e-40 136.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KXX80597.1 - 3.5e-05 23.5 0.6 0.0002 21.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX80597.1 - 0.00021 21.3 0.5 0.014 15.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KXX80597.1 - 0.00022 20.3 0.0 0.00064 18.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KXX80597.1 - 0.0005 20.2 1.0 0.02 15.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.9 KXX80597.1 - 0.00088 19.2 0.2 0.0074 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KXX80597.1 - 0.0064 15.7 0.3 0.044 13.0 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KXX80597.1 - 0.0065 15.6 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KXX80597.1 - 0.0091 14.9 0.0 0.02 13.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KXX80597.1 - 0.0099 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX80597.1 - 0.017 14.8 0.4 0.043 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KXX80597.1 - 0.021 14.2 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KXX80597.1 - 0.026 13.9 1.4 0.32 10.3 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KXX80597.1 - 0.05 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX80597.1 - 0.092 13.5 0.1 0.092 13.5 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KXX80597.1 - 0.33 10.4 2.0 0.76 9.3 0.0 2.3 2 2 0 2 2 2 0 AAA domain Amino_oxidase PF01593.19 KXX80598.1 - 6.8e-35 121.0 0.6 5.7e-34 117.9 0.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX80598.1 - 7.8e-12 45.0 0.0 2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX80598.1 - 0.0018 18.3 0.0 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX80598.1 - 0.018 15.4 0.0 0.068 13.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX80598.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KXX80598.1 - 0.089 11.8 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KXX80598.1 - 0.13 10.7 0.0 0.25 9.7 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein F_bP_aldolase PF01116.15 KXX80599.1 - 8.9e-85 284.2 0.1 1e-84 284.0 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LacAB_rpiB PF02502.13 KXX80600.1 - 2.9e-41 140.4 1.3 3.3e-41 140.2 0.9 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF3773 PF12608.3 KXX80600.1 - 0.024 14.6 0.1 0.072 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3773) TIM PF00121.13 KXX80602.1 - 5.8e-53 179.4 0.0 6.6e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase NmrA PF05368.8 KXX80603.1 - 2.4e-07 30.2 0.0 4.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX80603.1 - 2.1e-06 27.9 0.1 1.1e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Glyco_hydro_61 PF03443.9 KXX80605.1 - 2.4e-40 138.6 0.0 2.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 KXX80606.1 - 8.3e-44 149.7 49.9 2.7e-42 144.7 34.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Dispanin PF04505.7 KXX80606.1 - 0.73 9.4 0.0 0.73 9.4 0.0 4.1 5 1 1 6 6 6 0 Interferon-induced transmembrane protein Mito_fiss_reg PF05308.6 KXX80607.1 - 2.9 7.2 5.5 3.8 6.8 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Ish1 PF10281.4 KXX80608.1 - 1.3e-89 293.7 14.2 3e-14 52.7 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 KXX80608.1 - 2.6e-13 49.0 0.0 0.11 12.0 0.0 8.6 9 0 0 9 9 9 3 SAP domain Slx4 PF09494.5 KXX80608.1 - 4e-08 32.8 7.1 0.18 11.5 0.0 6.7 8 0 0 8 8 8 3 Slx4 endonuclease HeH PF12949.2 KXX80608.1 - 3.2e-07 29.7 0.0 4.4 6.9 0.0 6.8 7 2 0 7 7 7 2 HeH/LEM domain APC2 PF08672.6 KXX80608.1 - 2.2e-05 24.6 2.9 33 4.8 0.0 6.9 8 0 0 8 8 8 0 Anaphase promoting complex (APC) subunit 2 SAM_2 PF07647.12 KXX80608.1 - 0.057 13.2 0.8 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Thioredoxin_6 PF13848.1 KXX80608.1 - 0.069 12.9 0.0 2.6 7.8 0.0 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain DUF1470 PF07336.6 KXX80608.1 - 0.29 11.4 13.1 4.1 7.7 0.2 5.3 4 1 3 7 7 7 0 Protein of unknown function (DUF1470) TrbL PF04610.9 KXX80608.1 - 0.76 9.4 5.0 12 5.5 0.0 2.3 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2795 PF11387.3 KXX80608.1 - 1.3 8.9 5.0 19 5.1 0.1 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) Homeobox_KN PF05920.6 KXX80608.1 - 2.8 7.7 6.5 3.7 7.3 0.0 3.9 3 1 1 4 4 4 0 Homeobox KN domain DUF1996 PF09362.5 KXX80609.1 - 2.6e-88 295.6 2.4 3.2e-88 295.3 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MMR_HSR1 PF01926.18 KXX80610.1 - 1.4e-09 37.9 0.0 5e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KXX80610.1 - 0.00026 20.1 0.0 0.00076 18.6 0.0 1.8 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KXX80610.1 - 0.0003 19.8 0.0 0.001 18.1 0.0 1.8 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 KXX80610.1 - 0.0007 18.8 1.1 0.0024 17.0 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KXX80610.1 - 0.001 19.3 2.8 0.0047 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX80610.1 - 0.0086 16.8 7.1 0.27 12.0 4.9 2.5 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KXX80610.1 - 0.01 15.6 20.0 0.036 13.8 0.1 4.7 3 2 1 4 4 4 0 Dynamin family AAA_22 PF13401.1 KXX80610.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KXX80610.1 - 0.039 13.6 0.4 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KXX80610.1 - 0.046 13.0 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.8 KXX80610.1 - 0.072 11.9 2.1 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.1 KXX80610.1 - 0.12 11.7 1.2 0.37 10.1 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 KXX80610.1 - 0.25 11.1 0.1 0.25 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KXX80610.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.9 3 2 0 3 3 2 0 ABC transporter Miro PF08477.8 KXX80610.1 - 0.37 11.3 0.0 0.37 11.3 0.0 2.6 3 1 0 3 3 3 0 Miro-like protein DUF948 PF06103.6 KXX80610.1 - 1.1 9.1 7.5 2 8.3 2.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 KXX80610.1 - 9.3 6.2 35.1 6.2 6.7 17.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Rad60-SLD_2 PF13881.1 KXX80611.1 - 0.00048 19.9 0.1 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KXX80611.1 - 0.00082 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KXX80611.1 - 0.0031 17.6 0.2 0.01 15.9 0.0 1.9 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 KXX80611.1 - 0.0064 16.1 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3886 PF13025.1 KXX80611.1 - 0.064 13.2 0.7 0.18 11.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) NAD_binding_11 PF14833.1 KXX80612.1 - 1.6e-28 99.2 0.9 5.7e-20 71.5 0.1 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pre-SET PF05033.11 KXX80612.1 - 3e-20 72.4 2.0 5e-20 71.6 1.4 1.4 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.23 KXX80612.1 - 2.8e-19 70.0 0.8 5.1e-18 65.8 0.0 2.9 2 1 0 2 2 2 1 SET domain Ank_5 PF13857.1 KXX80613.1 - 3.4e-11 43.0 0.0 4.1e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX80613.1 - 1.5e-06 28.5 0.0 4.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX80613.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX80613.1 - 0.0078 16.3 0.0 0.057 13.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 KXX80613.1 - 0.042 13.6 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat DUF1292 PF06949.6 KXX80613.1 - 0.18 12.1 1.9 0.54 10.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1292) Ribonuc_P_40 PF08584.6 KXX80614.1 - 1.3e-68 231.0 0.0 1.9e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit EF_assoc_1 PF08355.7 KXX80614.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated Glycos_transf_3 PF00591.16 KXX80615.1 - 1.1e-61 208.4 0.0 3.6e-61 206.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KXX80615.1 - 2.1e-09 36.8 0.0 1e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain RNA_lig_T4_1 PF09511.5 KXX80616.1 - 8.6e-81 270.6 0.0 1.7e-80 269.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KXX80616.1 - 9.6e-80 267.4 0.0 1.3e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KXX80616.1 - 3.1e-57 193.0 0.0 6e-57 192.1 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain Mago_nashi PF02792.9 KXX80617.1 - 7.2e-76 252.7 0.3 8.4e-76 252.5 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 KXX80618.1 - 3.4e-93 312.7 5.9 5.8e-93 311.9 4.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KXX80618.1 - 8.4e-62 206.9 0.3 1.8e-61 205.9 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KXX80618.1 - 3.3e-61 204.7 0.0 9.9e-61 203.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KXX80618.1 - 4.8e-10 39.5 10.5 1.6e-05 25.0 0.0 4.9 2 1 3 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KXX80618.1 - 3e-06 27.2 8.2 0.0009 19.1 0.0 4.0 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KXX80618.1 - 0.00018 21.3 1.3 0.68 10.1 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KXX80618.1 - 0.06 13.8 1.4 9.3 6.8 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat RE_Alw26IDE PF09665.5 KXX80618.1 - 0.98 8.0 6.5 0.45 9.1 0.6 2.8 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Flu_M1_C PF08289.6 KXX80618.1 - 2.2 8.3 5.0 4.8 7.2 0.2 3.2 2 1 1 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain UPF0020 PF01170.13 KXX80619.1 - 3.4e-09 36.5 0.3 4.5e-08 32.8 0.2 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KXX80619.1 - 2.3e-06 27.6 0.0 5.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 KXX80619.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Vac_ImportDeg PF09783.4 KXX80620.1 - 5.8e-71 237.6 0.6 7.7e-71 237.2 0.4 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein GFA PF04828.9 KXX80621.1 - 2.1e-15 56.3 0.9 3.1e-15 55.8 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme 3HCDH_N PF02737.13 KXX80622.1 - 8.6e-25 87.4 0.0 3.3e-24 85.5 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KXX80622.1 - 6.9e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KXX80622.1 - 0.0024 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KXX80622.1 - 0.0028 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KXX80622.1 - 0.0048 17.2 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KXX80622.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Mito_carr PF00153.22 KXX80623.1 - 2.7e-68 225.7 0.1 1.9e-22 78.7 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein RBM1CTR PF08081.6 KXX80623.1 - 0.6 9.8 2.9 0.24 11.1 0.2 1.6 2 0 0 2 2 2 0 RBM1CTR (NUC064) family SKG6 PF08693.5 KXX80625.1 - 2e-06 27.0 0.0 2e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain GPI-anchored PF10342.4 KXX80625.1 - 0.014 15.8 0.2 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4229 PF14012.1 KXX80625.1 - 0.15 12.0 1.2 0.84 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Zip PF02535.17 KXX80626.1 - 1.1e-22 80.4 41.3 1.5e-12 47.1 9.7 4.5 2 1 2 4 4 4 2 ZIP Zinc transporter Metal_CEHH PF14455.1 KXX80626.1 - 0.11 11.8 0.1 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Predicted metal binding domain Fungal_trans PF04082.13 KXX80627.1 - 5.1e-22 77.9 0.3 2.2e-21 75.9 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX80627.1 - 3e-09 36.6 11.0 5.3e-09 35.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KXX80628.1 - 1.4e-07 31.6 0.2 3.8e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX80628.1 - 4.7e-07 29.6 0.3 1.3e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.1 KXX80628.1 - 5.7e-07 29.7 0.5 2.4e-06 27.6 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.7 KXX80628.1 - 8.2e-05 22.3 0.3 0.0002 21.0 0.2 1.6 1 0 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KXX80628.1 - 8.8e-05 22.2 0.0 0.00028 20.6 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX80628.1 - 0.00012 21.4 0.1 0.00033 20.0 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 KXX80628.1 - 0.0002 21.5 0.0 0.00081 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain LCAT PF02450.10 KXX80628.1 - 0.00038 19.5 0.2 0.0036 16.3 0.0 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase NB-ARC PF00931.17 KXX80628.1 - 0.00039 19.3 0.4 0.00039 19.3 0.3 2.2 3 0 0 3 3 3 1 NB-ARC domain AAA_19 PF13245.1 KXX80628.1 - 0.00049 19.7 0.1 0.0023 17.6 0.0 2.2 2 1 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 KXX80628.1 - 0.0011 18.8 0.2 0.0059 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KXX80628.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX80628.1 - 0.027 15.2 0.0 0.12 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KXX80628.1 - 0.044 12.5 0.0 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein WD40 PF00400.27 KXX80628.1 - 0.051 13.4 11.6 0.39 10.6 0.1 6.0 7 0 0 7 7 6 0 WD domain, G-beta repeat NTPase_1 PF03266.10 KXX80628.1 - 0.057 13.1 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 KXX80628.1 - 0.076 12.4 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.9 KXX80629.1 - 4.1e-36 124.4 0.0 5.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KXX80629.1 - 0.00012 21.8 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 KXX80629.1 - 0.012 15.1 1.9 0.021 14.3 1.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KXX80629.1 - 0.23 10.1 8.6 0.35 9.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PG_binding_2 PF08823.6 KXX80631.1 - 0.0039 17.2 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF1764 PF08576.5 KXX80631.1 - 8 7.3 10.4 4.9 7.9 1.8 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Melibiase PF02065.13 KXX80633.1 - 5.9e-16 58.1 0.0 9.9e-13 47.5 0.0 2.4 2 1 0 2 2 2 2 Melibiase GST_N_3 PF13417.1 KXX80634.1 - 4.6e-10 39.5 0.4 3.2e-09 36.8 0.3 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX80634.1 - 4.8e-09 36.1 0.1 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX80634.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX80634.1 - 3.2e-05 23.8 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX80634.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KXX80635.1 - 3.9e-21 75.1 37.0 1.2e-19 70.3 6.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX80635.1 - 5.9e-07 28.4 3.8 1.4e-06 27.2 2.6 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KXX80635.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.9 5 0 0 5 5 5 0 MFS_1 like family FAD_binding_4 PF01565.18 KXX80636.1 - 6.3e-23 80.7 3.0 1.4e-15 57.0 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 KXX80636.1 - 1.6e-17 63.1 0.8 2.8e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX80636.1 - 0.016 14.3 1.1 0.027 13.5 0.8 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.6 KXX80637.1 - 3.8e-28 98.3 0.0 8.4e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KXX80641.1 - 4.8e-37 127.5 0.0 6.2e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80641.1 - 2.8e-16 59.3 0.0 5.1e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX80641.1 - 8.3e-05 21.6 0.0 0.0002 20.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 KXX80641.1 - 0.046 13.6 0.2 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.9 KXX80641.1 - 0.065 12.2 0.1 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.6 KXX80643.1 - 2.6e-30 105.4 0.0 5.3e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TFCD_C PF12612.3 KXX80644.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF4360 PF14273.1 KXX80645.1 - 2.2e-34 118.7 0.4 2.7e-34 118.4 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Glyco_hydro_61 PF03443.9 KXX80646.1 - 4.8e-48 163.8 0.0 3.6e-41 141.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX80646.1 - 1.1e-12 47.4 8.3 1.1e-12 47.4 5.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Aldo_ket_red PF00248.16 KXX80647.1 - 4.1e-68 229.2 0.0 5.1e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 KXX80648.1 - 5.7e-24 83.6 0.0 1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.14 KXX80648.1 - 0.014 15.0 18.2 0.34 10.7 2.7 3.7 2 0 0 2 2 2 0 AT hook motif NUDIX PF00293.23 KXX80649.1 - 4.7e-10 39.2 0.0 4.9e-09 35.9 0.0 2.5 1 1 0 1 1 1 1 NUDIX domain DUF4066 PF13278.1 KXX80650.1 - 7.2e-13 48.1 0.0 9.7e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX80650.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family XLF PF09302.6 KXX80651.1 - 2.1e-37 128.5 0.0 2.9e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 KXX80652.1 - 1.7e-15 56.1 10.0 2.7e-09 36.5 0.4 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 KXX80652.1 - 0.0008 19.2 0.4 0.0024 17.6 0.3 1.8 1 0 0 1 1 1 1 Ribosomal L37ae protein family eIF2A PF08662.6 KXX80652.1 - 0.037 13.7 0.0 0.66 9.6 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ribosomal_S21e PF01249.13 KXX80653.1 - 1.4e-38 130.6 0.1 1.6e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Fork_head PF00250.13 KXX80654.1 - 6.1e-14 51.8 1.1 1.3e-13 50.8 0.8 1.6 1 1 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 KXX80655.1 - 1.4e-64 216.9 7.3 1.8e-64 216.5 5.1 1.1 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KXX80655.1 - 2.9e-51 172.2 2.9 3.4e-49 165.5 0.7 2.3 2 0 0 2 2 2 2 Cactus-binding C-terminus of cactin protein Phosphoprotein PF00922.12 KXX80655.1 - 0.054 12.7 1.0 0.11 11.6 0.7 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF1087 PF06465.8 KXX80655.1 - 0.69 9.8 5.0 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) cNMP_binding PF00027.24 KXX80658.1 - 1.9e-35 120.5 0.0 1.6e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box PF00646.28 KXX80658.1 - 2.7e-07 30.0 0.3 2.7e-07 30.0 0.2 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KXX80658.1 - 6.9e-07 28.8 2.1 1.3e-06 28.0 0.7 2.1 2 0 0 2 2 2 1 F-box-like Cupin_3 PF05899.7 KXX80658.1 - 0.082 12.3 0.0 5.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Bax1-I PF01027.15 KXX80659.1 - 4.2e-32 111.4 9.4 5.9e-32 110.9 6.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.16 KXX80660.1 - 1.3e-58 197.3 0.1 1.5e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SH3_1 PF00018.23 KXX80660.1 - 3.4 7.1 5.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 SH3 domain AAA PF00004.24 KXX80661.1 - 1.9e-15 57.2 0.0 3.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX80661.1 - 0.00014 21.9 1.5 0.027 14.6 0.0 2.7 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KXX80661.1 - 0.0005 20.1 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KXX80661.1 - 0.0012 17.9 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX80661.1 - 0.0015 18.1 0.0 0.005 16.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KXX80661.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX80661.1 - 0.053 14.3 0.5 0.68 10.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KXX80661.1 - 0.088 13.1 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain NUDIX PF00293.23 KXX80662.1 - 4.6e-18 65.1 0.2 5.3e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain LRR_6 PF13516.1 KXX80663.1 - 2.2e-10 39.5 1.5 0.083 13.0 0.0 5.3 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 KXX80663.1 - 3.5e-06 26.3 1.7 1.1 9.5 0.1 5.2 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.1 KXX80663.1 - 0.00012 21.7 1.6 0.035 13.8 0.2 3.2 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 KXX80663.1 - 0.013 15.0 0.0 13 5.5 0.0 3.1 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KXX80663.1 - 0.045 13.9 9.8 6.4 7.4 0.1 5.4 6 0 0 6 6 6 0 Leucine rich repeat Ste50p-SAM PF09235.5 KXX80663.1 - 0.079 12.9 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Ste50p, sterile alpha motif AAA PF00004.24 KXX80664.1 - 1.4e-12 47.9 0.2 8.4e-12 45.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX80664.1 - 0.00026 21.1 0.0 0.00079 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX80664.1 - 0.0051 16.5 0.9 0.027 14.2 0.6 2.3 1 0 0 1 1 1 1 Part of AAA domain Gp_dh_C PF02800.15 KXX80665.1 - 7.6e-77 256.1 0.0 1.1e-76 255.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KXX80665.1 - 9.2e-60 200.9 0.0 1.5e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KXX80665.1 - 0.0035 17.2 0.2 0.012 15.4 0.1 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus PTH2 PF01981.11 KXX80667.1 - 2.4e-46 156.1 0.3 3.3e-46 155.7 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hist_deacetyl PF00850.14 KXX80668.1 - 9.1e-88 294.5 0.0 1.4e-87 293.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KXX80668.1 - 6.2e-45 152.8 0.0 9.7e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain WHIM3 PF15614.1 KXX80670.1 - 0.035 13.8 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 Ras PF00071.17 KXX80671.1 - 1.2e-48 164.5 0.9 4.2e-44 149.7 0.1 2.2 1 1 1 2 2 2 2 Ras family Miro PF08477.8 KXX80671.1 - 2.6e-19 69.8 0.1 5.3e-19 68.8 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KXX80671.1 - 9.2e-11 41.2 0.1 1.1e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KXX80671.1 - 9.4e-08 32.0 0.1 1.3e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 KXX80671.1 - 0.00022 20.4 0.4 0.00026 20.1 0.3 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX80671.1 - 0.00049 20.2 0.1 0.0031 17.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 KXX80671.1 - 0.0014 17.7 0.1 0.0025 16.9 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KXX80671.1 - 0.0019 17.4 0.1 0.0027 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KXX80671.1 - 0.01 16.0 0.1 0.017 15.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 KXX80671.1 - 0.013 14.9 0.1 0.21 10.9 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KXX80671.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.6 KXX80671.1 - 0.027 14.1 0.1 0.057 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_24 PF13479.1 KXX80671.1 - 0.03 13.9 0.1 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX80671.1 - 0.032 14.2 0.1 0.071 13.0 0.1 1.7 1 1 1 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KXX80671.1 - 0.032 13.4 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KXX80671.1 - 0.069 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 KXX80671.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KXX80671.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 KXX80671.1 - 0.25 11.2 3.3 0.76 9.6 2.3 1.8 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 KXX80672.1 - 4.1e-10 39.1 0.5 9.7e-10 37.9 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.2 KXX80673.1 - 0.00013 21.6 1.1 0.00039 20.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like Brix PF04427.13 KXX80674.1 - 7.7e-39 133.3 0.0 9.9e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain UbiA PF01040.13 KXX80675.1 - 1.4e-31 109.6 21.6 1.9e-31 109.1 15.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 KXX80676.1 - 6.9e-41 138.4 0.6 8.2e-41 138.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MitMem_reg PF13012.1 KXX80677.1 - 2.2e-38 130.8 0.1 5.3e-38 129.6 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KXX80677.1 - 1.5e-28 98.8 0.0 3.1e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SWIM PF04434.12 KXX80678.1 - 0.0012 18.2 0.5 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger Coprogen_oxidas PF01218.13 KXX80679.1 - 6.9e-134 445.0 0.1 8.1e-134 444.8 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 KXX80680.1 - 2.7e-51 171.8 0.2 3.2e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KXX80680.1 - 2.5e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 T2SM PF04612.7 KXX80681.1 - 1.4 8.6 7.3 0.1 12.3 1.6 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M SSP160 PF06933.6 KXX80681.1 - 2 6.3 6.9 3.5 5.5 4.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADK PF00406.17 KXX80682.1 - 1.9e-58 196.6 0.0 2.4e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KXX80682.1 - 5.7e-15 54.6 0.0 1.7e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KXX80682.1 - 7.9e-07 29.9 0.1 1.9e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX80682.1 - 0.00018 21.4 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KXX80682.1 - 0.003 16.6 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KXX80682.1 - 0.021 15.1 1.5 0.085 13.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain HOOK PF05622.7 KXX80683.1 - 1.5e-15 56.1 51.4 1.5e-15 56.1 35.6 2.7 1 1 2 3 3 3 1 HOOK protein DUF904 PF06005.7 KXX80683.1 - 0.00028 21.0 2.5 0.00028 21.0 1.7 8.4 6 3 1 7 7 7 2 Protein of unknown function (DUF904) CH PF00307.26 KXX80683.1 - 0.0018 18.3 0.0 0.0076 16.2 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain bZIP_1 PF00170.16 KXX80683.1 - 0.012 15.5 2.4 0.012 15.5 1.7 9.6 6 2 5 11 11 11 0 bZIP transcription factor KR PF08659.5 KXX80683.1 - 3.5 7.2 10.4 1.9 8.1 0.4 3.5 3 1 0 3 3 3 0 KR domain Inhibitor_I9 PF05922.11 KXX80684.1 - 0.0011 19.5 0.1 0.0015 19.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 KXX80684.1 - 0.1 11.7 0.1 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) C2 PF00168.25 KXX80686.1 - 1.9e-21 75.6 0.0 8.5e-15 54.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain DUF3043 PF11241.3 KXX80686.1 - 0.027 14.0 5.9 0.078 12.5 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Gon7 PF08738.5 KXX80687.1 - 1.6e-15 56.9 1.7 3.1e-15 56.0 1.2 1.4 1 1 0 1 1 1 1 Gon7 family GCOM2 PF15328.1 KXX80687.1 - 0.038 13.7 1.7 0.045 13.5 1.2 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF3684 PF12449.3 KXX80687.1 - 0.067 10.7 0.3 0.073 10.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) cobW PF02492.14 KXX80688.1 - 6.5e-35 120.1 0.0 8.1e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KXX80688.1 - 1.5e-06 27.1 0.7 1.1e-05 24.3 0.5 1.9 1 1 0 1 1 1 1 ArgK protein AAA_23 PF13476.1 KXX80688.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KXX80688.1 - 0.067 12.5 0.7 0.12 11.7 0.3 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KXX80688.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KXX80688.1 - 0.15 12.9 0.4 0.36 11.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KXX80688.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4066 PF13278.1 KXX80689.1 - 8.5e-25 86.9 0.0 1.6e-24 86.0 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KXX80689.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family AARP2CN PF08142.7 KXX80690.1 - 1.4e-19 69.4 0.0 2.8e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KXX80690.1 - 0.0067 15.8 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF663 PF04950.7 KXX80691.1 - 1.1e-104 349.6 0.0 1.4e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AAA_17 PF13207.1 KXX80692.1 - 9e-06 26.5 0.0 2.7e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 KXX80692.1 - 0.00044 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KXX80692.1 - 0.003 17.8 0.0 0.0076 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KXX80692.1 - 0.0059 16.1 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KXX80692.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain BING4CT PF08149.6 KXX80693.1 - 9.8e-40 133.9 0.0 2.6e-37 126.1 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KXX80693.1 - 1.1e-07 31.4 0.0 1.7e-05 24.4 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.1 KXX80693.1 - 0.034 13.6 0.0 0.12 11.8 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain AviRa PF11599.3 KXX80693.1 - 0.09 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Glyco_hydro_15 PF00723.16 KXX80695.1 - 6.9e-104 347.8 0.0 8.2e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KXX80695.1 - 4.6e-33 112.6 0.2 9.5e-33 111.6 0.2 1.5 1 0 0 1 1 1 1 Starch binding domain DUF3328 PF11807.3 KXX80696.1 - 0.13 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SART-1 PF03343.8 KXX80697.1 - 6e-168 559.9 48.6 6.9e-168 559.7 33.7 1.0 1 0 0 1 1 1 1 SART-1 family DUF4050 PF13259.1 KXX80698.1 - 9.8e-34 115.8 0.0 9.8e-34 115.8 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) Neur_chan_memb PF02932.11 KXX80698.1 - 0.21 11.4 3.4 0.21 11.4 1.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 KXX80699.1 - 5.2e-48 164.2 4.5 3.1e-47 161.6 3.1 2.0 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KXX80699.1 - 1.2e-32 113.4 40.4 2.1e-32 112.6 28.0 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KXX80699.1 - 5.5e-13 48.2 47.9 2.3e-10 39.5 19.7 2.8 1 1 2 3 3 3 3 Citrate transporter Vps39_1 PF10366.4 KXX80700.1 - 5.8e-33 113.1 0.0 4.3e-32 110.3 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KXX80700.1 - 1e-29 102.8 0.0 2.6e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KXX80700.1 - 1.6e-18 67.1 0.0 6.3e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KXX80700.1 - 0.00029 20.4 2.0 0.00067 19.2 0.1 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 KXX80700.1 - 0.032 13.8 4.6 0.46 10.1 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80700.1 - 0.036 14.3 0.1 7.2 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF499 PF04465.7 KXX80700.1 - 0.073 10.6 0.0 0.11 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) TPR_2 PF07719.12 KXX80700.1 - 0.19 11.7 0.9 15 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat bZIP_2 PF07716.10 KXX80701.1 - 0.22 11.3 2.1 0.51 10.2 1.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper EssA PF10661.4 KXX80702.1 - 0.67 9.6 8.9 7.3 6.2 5.8 2.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA RNA_pol_Rbc25 PF08292.7 KXX80702.1 - 4.1 7.6 6.9 6.3 7.0 1.0 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PAPA-1 PF04795.7 KXX80703.1 - 2.6e-27 95.3 2.9 1.3e-26 93.0 2.0 2.2 1 0 0 1 1 1 1 PAPA-1-like conserved region Herpes_BLLF1 PF05109.8 KXX80703.1 - 0.75 7.6 8.5 1 7.2 5.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Daxx PF03344.10 KXX80703.1 - 1.5 7.2 21.8 2 6.7 15.1 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KXX80703.1 - 2 7.4 22.6 2.7 6.9 15.7 1.3 1 0 0 1 1 1 0 BUD22 Pex14_N PF04695.8 KXX80704.1 - 1.6e-22 80.0 0.1 1.6e-22 80.0 0.1 2.9 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HbrB PF08539.6 KXX80705.1 - 4.9e-57 192.2 0.0 8e-57 191.5 0.0 1.3 1 0 0 1 1 1 1 HbrB-like LIM_bind PF01803.11 KXX80706.1 - 5e-80 268.0 0.1 5e-80 268.0 0.1 5.5 3 2 2 5 5 5 1 LIM-domain binding protein DUF4452 PF14618.1 KXX80707.1 - 3.2e-81 271.0 10.3 4e-81 270.6 7.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) BTB PF00651.26 KXX80708.1 - 3.8e-05 23.6 0.0 6.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain JmjC PF02373.17 KXX80709.1 - 4.1e-11 43.1 0.2 6.3e-10 39.2 0.1 2.7 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KXX80709.1 - 3.9e-07 30.1 7.9 3.9e-07 30.1 5.5 2.9 3 1 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KXX80709.1 - 0.044 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF4228 PF14009.1 KXX80710.1 - 0.086 12.9 0.1 0.086 12.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) EF-hand_7 PF13499.1 KXX80711.1 - 3.2e-25 88.0 2.1 2e-13 50.2 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KXX80711.1 - 7e-23 78.1 3.4 9.1e-06 24.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 KXX80711.1 - 5.6e-18 63.4 8.4 1.2e-05 24.3 1.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KXX80711.1 - 1.8e-17 61.5 7.6 5.5e-05 22.7 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KXX80711.1 - 4.1e-17 61.5 5.9 3.6e-08 32.9 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KXX80711.1 - 3.3e-08 33.5 0.0 3.3e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KXX80711.1 - 0.00016 21.3 1.2 0.2 11.3 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 KXX80711.1 - 0.0035 16.9 1.2 1.4 8.6 0.0 2.6 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KXX80711.1 - 0.064 13.1 0.0 3 7.8 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain TauD PF02668.11 KXX80712.1 - 2.9e-38 132.0 0.6 3.3e-38 131.8 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyclin_N PF00134.18 KXX80713.1 - 7.2e-12 44.9 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Piwi PF02171.12 KXX80714.1 - 9.2e-06 24.8 0.2 2.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Piwi domain Lgl_C PF08596.5 KXX80715.1 - 8.3e-117 389.9 0.0 1.3e-116 389.3 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KXX80715.1 - 2.2e-06 27.2 0.6 0.083 12.8 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat MFS_1 PF07690.11 KXX80716.1 - 2.8e-40 138.1 29.0 3.9e-40 137.6 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 KXX80718.1 - 6.5e-61 205.9 0.1 9.8e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX80718.1 - 6e-13 48.2 12.9 2e-12 46.5 8.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Clp1 PF06807.9 KXX80719.1 - 7.5e-07 29.1 0.0 1.9e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Glyco_hydro_61 PF03443.9 KXX80720.1 - 6.5e-61 205.9 0.1 9.8e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX80720.1 - 6e-13 48.2 12.9 2e-12 46.5 8.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Gti1_Pac2 PF09729.4 KXX80721.1 - 1.6e-46 158.2 1.0 1.6e-46 158.2 0.7 3.0 2 2 0 2 2 2 1 Gti1/Pac2 family Macoilin PF09726.4 KXX80721.1 - 3.9 5.6 5.9 5.1 5.2 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein RasGAP PF00616.14 KXX80722.1 - 5.2e-54 182.9 0.2 3.5e-53 180.2 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KXX80722.1 - 8.2e-29 100.1 5.8 8.2e-29 100.1 4.0 2.6 3 0 0 3 3 3 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 KXX80722.1 - 0.049 13.5 0.2 0.049 13.5 0.1 1.7 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain DUF972 PF06156.8 KXX80722.1 - 2.4 8.5 9.1 17 5.7 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 KXX80723.1 - 1.4e-30 106.2 38.7 5.3e-30 104.3 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX80723.1 - 3.3e-06 25.9 8.6 3.3e-06 25.9 6.0 2.4 3 1 0 3 3 3 1 Sugar (and other) transporter tRNA-synt_2 PF00152.15 KXX80724.1 - 5.7e-56 189.7 0.0 8.6e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2263 PF10021.4 KXX80725.1 - 1.1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SMC_N PF02463.14 KXX80727.1 - 3.7e-77 258.4 3.9 1.5e-76 256.5 2.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KXX80727.1 - 1.6e-27 95.8 0.3 1.7e-26 92.5 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KXX80727.1 - 1.9e-11 44.5 8.9 2.2e-05 24.5 0.0 3.3 4 1 0 4 4 4 2 AAA domain Filament PF00038.16 KXX80727.1 - 7.7e-05 22.3 44.6 7.7e-05 22.3 30.9 4.7 3 1 0 3 3 2 1 Intermediate filament protein AAA_29 PF13555.1 KXX80727.1 - 0.0003 20.2 0.0 0.0008 18.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_I PF06008.9 KXX80727.1 - 0.0008 18.8 35.5 0.0008 18.8 24.6 6.1 3 2 2 5 5 4 2 Laminin Domain I Tropomyosin_1 PF12718.2 KXX80727.1 - 0.00094 19.0 15.0 0.00094 19.0 10.4 7.5 3 2 3 7 7 5 1 Tropomyosin like AAA_13 PF13166.1 KXX80727.1 - 0.0013 17.2 100.4 0.023 13.2 20.2 5.6 3 2 2 5 5 5 3 AAA domain DUF1664 PF07889.7 KXX80727.1 - 0.0072 16.1 4.6 0.0072 16.1 3.2 6.8 3 2 3 7 7 7 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 KXX80727.1 - 0.11 12.2 109.9 0.067 12.9 6.3 8.7 1 1 6 8 8 8 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KXX80727.1 - 0.34 10.0 29.9 0.0076 15.4 1.4 4.5 3 2 3 6 6 6 0 Reovirus sigma C capsid protein IncA PF04156.9 KXX80727.1 - 0.46 10.0 126.4 0.0065 16.0 9.4 8.2 3 2 4 7 7 6 0 IncA protein DUF3040 PF11239.3 KXX80727.1 - 1.8 8.6 4.3 0.59 10.2 0.3 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3040) ELYS PF13934.1 KXX80728.1 - 1e-63 215.0 0.0 1.3e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly HUN PF08729.5 KXX80729.1 - 9.8e-14 50.9 0.8 2.1e-13 49.9 0.5 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Glyco_hydro_3 PF00933.16 KXX80730.1 - 1.4e-93 313.1 0.0 2.3e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX80730.1 - 4.3e-57 193.2 0.0 1.5e-56 191.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX80730.1 - 1.1e-15 57.2 0.1 2e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ASF1_hist_chap PF04729.8 KXX80731.1 - 6.8e-68 227.1 0.1 9.3e-68 226.7 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.9 KXX80732.1 - 6e-82 275.5 4.7 3.8e-79 266.3 0.0 3.4 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KXX80732.1 - 1.5e-05 25.4 0.3 0.00019 21.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80732.1 - 2.3e-05 24.6 0.3 0.0021 18.5 0.4 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Sigma70_ner PF04546.8 KXX80732.1 - 0.00099 18.7 4.3 0.0031 17.1 3.0 1.8 1 0 0 1 1 1 1 Sigma-70, non-essential region TPR_19 PF14559.1 KXX80732.1 - 0.0012 19.1 0.0 0.028 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.11 KXX80732.1 - 0.027 14.2 0.8 0.58 9.9 0.1 2.9 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 KXX80732.1 - 1.1 9.9 3.9 3 8.5 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF1767 PF08585.7 KXX80733.1 - 5.7e-06 26.5 0.2 5.7e-06 26.5 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) DUF1498 PF07385.7 KXX80733.1 - 0.026 13.6 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) PIG-P PF08510.7 KXX80734.1 - 1.2 8.8 4.0 2.1 8.0 2.8 1.4 1 0 0 1 1 1 0 PIG-P XFP_N PF09364.5 KXX80735.1 - 5.1e-178 591.4 0.0 6.7e-178 591.0 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 KXX80735.1 - 1.4e-82 275.5 0.0 2.9e-82 274.5 0.0 1.5 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 KXX80735.1 - 1.7e-81 272.4 0.0 2.4e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Pkinase PF00069.20 KXX80737.1 - 1.8e-06 27.3 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KXX80737.1 - 0.031 14.0 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KXX80737.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PUF PF00806.14 KXX80738.1 - 2.9e-09 35.8 0.0 6.8 6.3 0.0 6.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat CPSF100_C PF13299.1 KXX80739.1 - 3.7e-44 150.7 0.4 9.5e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KXX80739.1 - 3.5e-27 94.8 0.0 7.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KXX80739.1 - 2.1e-07 30.6 0.0 4.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KXX80739.1 - 0.03 13.9 0.1 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Sec23_trunk PF04811.10 KXX80740.1 - 7.5e-53 179.3 0.0 5.2e-52 176.6 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KXX80740.1 - 1.3e-22 79.1 0.1 2.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KXX80740.1 - 7.1e-17 60.6 4.2 1.4e-16 59.7 2.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KXX80740.1 - 4.5e-13 49.5 0.1 1.7e-12 47.7 0.1 1.9 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KXX80740.1 - 1.3e-06 27.9 0.0 3.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps51 PF08700.6 KXX80741.1 - 7.1e-23 80.2 0.1 1.2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KXX80741.1 - 0.0087 16.0 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 KXX80741.1 - 0.042 12.3 0.2 0.063 11.7 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family FUSC PF04632.7 KXX80741.1 - 0.046 12.1 0.1 0.046 12.1 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fes1 PF08609.5 KXX80741.1 - 0.14 12.6 0.8 0.65 10.5 0.5 2.0 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 Ndc1_Nup PF09531.5 KXX80741.1 - 0.37 9.1 3.3 0.44 8.9 2.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF605 PF04652.11 KXX80741.1 - 9 5.5 13.1 11 5.3 9.1 1.2 1 0 0 1 1 1 0 Vta1 like Nrap PF03813.9 KXX80742.1 - 0 1111.4 0.0 0 1111.2 0.0 1.0 1 0 0 1 1 1 1 Nrap protein BolA PF01722.13 KXX80743.1 - 6.1e-23 80.5 0.0 7.4e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CorA PF01544.13 KXX80744.1 - 2.1e-11 43.4 0.3 5.9e-11 41.9 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein NIF3 PF01784.13 KXX80746.1 - 2.9e-59 200.5 0.0 3.6e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RPAP1_C PF08620.5 KXX80748.1 - 4.9e-30 103.1 0.0 9.6e-30 102.2 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KXX80748.1 - 2.1e-17 62.4 0.6 3.6e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal TPR_11 PF13414.1 KXX80749.1 - 4.1e-44 148.0 39.8 1.6e-08 34.0 0.0 11.8 9 3 2 11 11 11 10 TPR repeat TPR_16 PF13432.1 KXX80749.1 - 2.2e-38 130.1 61.4 8.6e-08 32.6 0.0 15.0 11 4 4 15 15 15 9 Tetratricopeptide repeat TPR_2 PF07719.12 KXX80749.1 - 8.7e-32 106.4 45.3 0.0024 17.6 0.0 16.5 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80749.1 - 3.3e-31 104.9 40.4 3.1e-05 24.2 0.0 16.8 13 6 5 18 18 17 7 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80749.1 - 1.1e-30 105.7 32.1 1.9e-05 24.8 1.1 11.7 10 2 1 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 KXX80749.1 - 9.6e-25 85.1 35.0 0.00044 19.7 0.0 14.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_17 PF13431.1 KXX80749.1 - 2e-23 80.5 16.1 0.14 12.4 0.0 15.5 17 0 0 17 17 16 6 Tetratricopeptide repeat TPR_8 PF13181.1 KXX80749.1 - 1.6e-20 71.2 20.4 0.012 15.3 0.0 12.6 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80749.1 - 3.2e-14 52.5 58.3 0.00018 21.3 0.1 13.4 8 6 9 17 17 17 8 Tetratricopeptide repeat TPR_7 PF13176.1 KXX80749.1 - 6.4e-13 47.4 31.4 0.002 17.7 0.0 13.5 13 1 1 14 14 14 3 Tetratricopeptide repeat TPR_6 PF13174.1 KXX80749.1 - 6.7e-11 41.9 29.3 0.022 15.1 0.0 14.2 17 0 0 17 17 16 1 Tetratricopeptide repeat TPR_9 PF13371.1 KXX80749.1 - 2e-06 27.5 19.8 0.022 14.5 0.0 8.8 9 1 0 9 9 9 2 Tetratricopeptide repeat ChAPs PF09295.5 KXX80749.1 - 0.011 14.5 4.9 4.9 5.8 0.3 4.1 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.9 KXX80749.1 - 0.016 14.0 0.1 0.036 12.8 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region TPR_4 PF07721.9 KXX80749.1 - 2.2 8.9 38.5 51 4.7 0.1 10.9 12 0 0 12 12 10 0 Tetratricopeptide repeat ketoacyl-synt PF00109.21 KXX80750.1 - 1.1e-78 264.3 0.2 1.1e-77 260.9 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KXX80750.1 - 1.1e-78 264.5 0.5 2.4e-78 263.4 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 KXX80750.1 - 2e-53 180.7 0.2 8.4e-51 172.1 0.0 2.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KXX80750.1 - 5.5e-48 163.0 0.1 2.5e-42 144.6 0.0 4.0 3 0 0 3 3 3 2 short chain dehydrogenase Condensation PF00668.15 KXX80750.1 - 2.9e-47 160.9 0.1 4.9e-47 160.2 0.1 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 KXX80750.1 - 1.6e-45 155.8 0.1 3.1e-45 154.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX80750.1 - 4.6e-44 150.7 4.3 8e-44 149.9 3.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KXX80750.1 - 1.8e-34 118.8 0.0 3.8e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KXX80750.1 - 1.7e-30 105.2 0.1 3e-29 101.2 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX80750.1 - 4.7e-20 71.9 0.0 1.3e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX80750.1 - 2.2e-15 56.6 1.4 2.3e-08 34.1 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KXX80750.1 - 2.2e-13 50.2 0.0 4.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KXX80750.1 - 4.1e-13 49.4 0.0 1.2e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 KXX80750.1 - 1.2e-12 47.7 0.0 1.4e-11 44.3 0.0 2.7 3 0 0 3 3 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KXX80750.1 - 1.7e-11 44.4 0.0 4.7e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80750.1 - 4.6e-08 32.7 0.0 9.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80750.1 - 1.1e-07 32.3 0.0 8.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80750.1 - 4.6e-07 30.1 0.0 1.3e-05 25.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 KXX80750.1 - 7.4e-07 28.1 0.0 3.3e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KXX80750.1 - 1.7e-06 27.3 0.0 3.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KXX80750.1 - 5.5e-05 22.2 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KXX80750.1 - 0.0039 16.8 1.0 0.014 15.0 0.7 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 KXX80750.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 KXX80750.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.12 KXX80750.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KXX80750.1 - 0.2 10.6 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 KXX80750.1 - 0.23 10.7 0.0 0.48 9.7 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DapB_N PF01113.15 KXX80750.1 - 0.26 11.1 0.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_29 PF03141.11 KXX80750.1 - 1 7.5 0.0 1.7 6.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Condensation PF00668.15 KXX80751.1 - 4.9e-245 810.3 0.0 2.4e-44 151.4 0.0 7.6 6 2 0 6 6 6 6 Condensation domain AMP-binding PF00501.23 KXX80751.1 - 1.8e-238 790.8 0.0 3.1e-79 266.3 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.20 KXX80751.1 - 3.2e-50 168.2 0.0 1.4e-15 57.3 0.0 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX80751.1 - 2.7e-13 50.6 0.8 1.8e-05 25.5 0.0 3.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KXX80751.1 - 1.2e-12 47.9 0.0 0.00068 19.9 0.0 5.7 5 0 0 5 5 5 2 HxxPF-repeated domain Transferase PF02458.10 KXX80751.1 - 7.3e-07 27.9 0.0 0.001 17.5 0.0 4.5 5 0 0 5 5 5 1 Transferase family 2-oxoacid_dh PF00198.18 KXX80751.1 - 0.0085 15.3 0.0 1.9 7.6 0.0 2.9 3 0 0 3 3 3 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) CorA PF01544.13 KXX80752.1 - 1.4e-10 40.7 0.0 3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pyr_redox_2 PF07992.9 KXX80753.1 - 8.5e-20 71.4 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX80753.1 - 1.1e-07 31.7 0.9 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX80753.1 - 8.7e-07 29.2 0.9 0.012 15.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX80753.1 - 1.6e-06 27.2 2.4 4.1e-05 22.6 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KXX80753.1 - 2.6e-05 23.3 0.4 0.00019 20.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KXX80753.1 - 5e-05 22.3 0.7 0.0011 17.9 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KXX80753.1 - 8.7e-05 21.5 1.7 0.16 10.8 0.1 2.1 1 1 1 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KXX80753.1 - 0.00045 18.7 0.2 0.0026 16.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KXX80753.1 - 0.0027 17.6 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX80753.1 - 0.0076 15.2 0.4 0.15 10.9 0.2 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX80753.1 - 0.088 11.8 0.2 0.32 9.9 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.12 KXX80753.1 - 0.094 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family MARVEL PF01284.18 KXX80754.1 - 8.2 6.2 12.0 29 4.4 8.4 1.9 1 1 0 1 1 1 0 Membrane-associating domain DUF2278 PF10042.4 KXX80756.1 - 1.8e-61 207.4 0.0 2.4e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.14 KXX80756.1 - 3.1e-08 33.7 0.3 7.4e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Lamin Tail Domain CorA PF01544.13 KXX80757.1 - 4.9e-06 25.7 0.3 1e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 KXX80757.1 - 0.0023 17.5 0.4 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat DUF3980 PF13140.1 KXX80757.1 - 0.098 12.9 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) TPR_12 PF13424.1 KXX80757.1 - 0.1 12.5 2.7 0.15 12.0 0.4 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.15 KXX80759.1 - 9.6e-26 89.4 0.0 1.4e-25 88.9 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KXX80759.1 - 1e-06 28.7 0.0 3.9e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KXX80759.1 - 3.3e-06 27.0 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KXX80759.1 - 1.4e-05 25.2 0.1 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KXX80759.1 - 2.5e-05 23.8 0.1 4.5e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KXX80759.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 KXX80759.1 - 0.00025 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KXX80759.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 KXX80759.1 - 0.041 13.3 0.0 0.058 12.8 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Dfp1_Him1_M PF08630.5 KXX80760.1 - 1.2e-31 109.0 0.0 3e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KXX80760.1 - 1.1e-24 85.7 0.1 1.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KXX80760.1 - 0.11 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FAR1 PF03101.10 KXX80762.1 - 1.1e-07 32.2 0.4 2e-07 31.4 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KXX80762.1 - 0.11 12.7 0.7 0.29 11.3 0.2 1.9 2 0 0 2 2 2 0 Transcription factor AFT DUF4288 PF14119.1 KXX80762.1 - 0.13 12.3 0.5 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) OTT_1508_deam PF14441.1 KXX80763.1 - 1.1e-19 70.6 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase SOR_SNZ PF01680.12 KXX80764.1 - 2e-102 341.1 9.1 2.8e-102 340.7 6.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KXX80764.1 - 6.6e-06 25.3 13.8 0.0018 17.3 2.4 2.8 1 1 2 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KXX80764.1 - 0.00015 20.6 0.2 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KXX80764.1 - 0.00029 20.1 1.0 0.024 13.9 0.1 2.4 2 0 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.9 KXX80764.1 - 0.015 14.2 2.3 0.11 11.4 0.0 2.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 KXX80764.1 - 0.039 12.4 0.0 0.078 11.4 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain IGPS PF00218.16 KXX80764.1 - 0.057 12.4 0.3 0.65 9.0 0.0 2.6 2 2 1 3 3 3 0 Indole-3-glycerol phosphate synthase DivIC PF04977.10 KXX80767.1 - 0.0028 17.0 9.9 0.86 9.1 0.2 4.0 3 1 0 3 3 3 2 Septum formation initiator CENP-F_leu_zip PF10473.4 KXX80767.1 - 0.029 14.2 16.7 0.38 10.6 4.1 3.6 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.6 KXX80767.1 - 0.034 13.9 8.2 1.9 8.3 0.0 4.0 3 1 0 4 4 4 0 GDP/GTP exchange factor Sec2p IncA PF04156.9 KXX80767.1 - 0.11 12.0 21.7 0.52 9.8 2.7 3.5 3 1 0 3 3 3 0 IncA protein Filament PF00038.16 KXX80767.1 - 0.15 11.5 13.9 0.16 11.4 5.9 2.8 2 1 0 2 2 2 0 Intermediate filament protein DUF724 PF05266.9 KXX80767.1 - 0.29 10.7 3.9 4.5 6.8 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) COG2 PF06148.6 KXX80767.1 - 0.75 9.6 12.1 5.8 6.8 0.7 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DegS PF05384.6 KXX80767.1 - 0.81 8.8 7.3 0.13 11.4 0.5 2.7 3 0 0 3 3 3 0 Sensor protein DegS TPR_MLP1_2 PF07926.7 KXX80767.1 - 1.2 8.8 17.0 1.5 8.5 1.9 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KXX80767.1 - 1.4 8.7 16.0 2.1 8.2 0.0 4.6 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KXX80767.1 - 2 8.7 7.5 50 4.2 0.0 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KXX80767.1 - 2.5 6.9 17.4 0.48 9.3 0.6 3.2 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KXX80767.1 - 5.7 7.4 11.8 2.7 8.4 0.3 3.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sin_N PF04801.8 KXX80769.1 - 4.7e-22 78.4 0.7 2.1e-21 76.2 0.5 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region SNO PF01174.14 KXX80770.1 - 6e-53 179.2 0.0 1e-41 142.6 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KXX80770.1 - 4.3e-11 42.6 0.1 4.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KXX80770.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KXX80770.1 - 0.00044 19.5 0.0 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 KXX80770.1 - 0.00053 19.4 0.0 0.098 12.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 KXX80770.1 - 0.0021 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 KXX80770.1 - 0.068 12.5 0.0 0.43 9.9 0.0 2.2 2 1 0 2 2 2 0 Peptidase C26 SR-25 PF10500.4 KXX80770.1 - 0.43 10.0 9.4 0.66 9.4 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein She9_MDM33 PF05546.6 KXX80771.1 - 3.8e-80 268.3 2.5 5.2e-80 267.9 1.7 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Tropomyosin_1 PF12718.2 KXX80771.1 - 0.002 17.9 0.4 0.002 17.9 0.2 1.7 2 0 0 2 2 2 1 Tropomyosin like PsbH PF00737.15 KXX80771.1 - 0.1 12.1 0.4 0.23 11.0 0.3 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Nup54 PF13874.1 KXX80771.1 - 0.23 11.1 3.2 0.21 11.2 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.3 KXX80771.1 - 0.26 11.1 4.1 0.11 12.4 1.0 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FAD-SLDH PF12318.3 KXX80771.1 - 0.53 9.9 3.9 0.22 11.2 0.7 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF2413 PF10310.4 KXX80771.1 - 0.62 8.8 8.1 1 8.0 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 KXX80771.1 - 0.72 8.0 8.5 1.1 7.4 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 KXX80771.1 - 1.1 8.5 23.9 1.9 7.8 16.6 1.3 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KXX80772.1 - 4.8e-62 209.4 0.0 8e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80772.1 - 4.9e-36 124.1 0.0 9.4e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KXX80772.1 - 5.1e-26 90.2 24.9 4.1e-16 58.4 3.0 2.7 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 KXX80772.1 - 3.3e-21 74.7 26.4 6e-12 45.1 6.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KXX80772.1 - 9.7e-15 54.8 2.6 2.8e-14 53.3 1.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KXX80772.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PHD PF00628.24 KXX80772.1 - 8 6.2 25.0 0.12 12.1 5.7 2.4 2 0 0 2 2 2 0 PHD-finger PAT1 PF09770.4 KXX80772.1 - 9.4 4.3 37.6 0.032 12.4 17.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HET PF06985.6 KXX80773.1 - 6.6e-27 94.3 0.1 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HATPase_c PF02518.21 KXX80774.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_transf_15 PF01793.11 KXX80775.1 - 2.2e-142 473.9 8.4 2.6e-142 473.6 5.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KXX80775.1 - 0.099 12.4 1.2 0.29 10.9 0.8 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor PAT1 PF09770.4 KXX80776.1 - 1.2e-229 764.6 24.0 1.3e-191 638.8 1.4 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Acyl-CoA_dh_1 PF00441.19 KXX80777.1 - 2.4e-38 131.5 3.9 4e-38 130.8 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX80777.1 - 2.9e-28 98.6 0.6 1.4e-27 96.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX80777.1 - 6e-17 62.1 1.0 1.1e-16 61.3 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KXX80777.1 - 5.3e-15 54.6 0.1 1.3e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 KXX80777.1 - 0.013 14.9 0.1 0.07 12.5 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.20 KXX80778.1 - 1.6e-40 137.3 0.8 2e-40 136.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Beta_elim_lyase PF01212.16 KXX80781.1 - 5.4e-55 186.5 0.0 8.9e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_DMAT PF11991.3 KXX80781.1 - 4.6e-20 72.1 0.0 7.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase HrpF PF06266.7 KXX80781.1 - 0.13 12.4 0.2 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 HrpF protein DUF4131 PF13567.1 KXX80782.1 - 2 7.7 9.0 1 8.7 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1705 PF08019.7 KXX80782.1 - 8.6 5.8 11.4 0.48 9.9 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1705) p450 PF00067.17 KXX80783.1 - 1.3e-62 211.8 0.0 1.6e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KXX80784.1 - 3.6e-14 52.4 0.4 5.9e-14 51.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX80784.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 KXX80785.1 - 6.6e-20 71.4 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80785.1 - 9.2e-08 32.6 0.0 2.8e-06 27.8 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX80785.1 - 1.6e-06 27.7 0.0 4.2e-05 23.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80785.1 - 1.2e-05 25.7 0.0 4.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX80785.1 - 0.00014 22.2 0.0 0.0027 18.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80785.1 - 0.00053 20.3 0.0 0.0028 17.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KXX80785.1 - 0.0052 16.7 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KXX80785.1 - 0.017 15.1 0.0 0.075 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KXX80785.1 - 0.052 12.5 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 KXX80785.1 - 0.13 11.2 0.0 0.79 8.7 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KXX80785.1 - 0.14 11.5 0.0 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Spindle_Spc25 PF08234.7 KXX80786.1 - 1.8e-22 79.0 0.2 5.7e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Syntaphilin PF15290.1 KXX80786.1 - 0.031 13.7 0.7 0.031 13.7 0.5 2.2 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Toxin_62 PF15540.1 KXX80786.1 - 0.034 14.2 0.1 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 62 SYF2 PF08231.7 KXX80786.1 - 0.31 11.1 9.7 0.57 10.2 6.7 1.4 1 0 0 1 1 1 0 SYF2 splicing factor Atg14 PF10186.4 KXX80786.1 - 3.9 6.3 13.4 1.4 7.7 7.6 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KXX80786.1 - 6.5 6.3 15.1 16 5.1 0.5 2.3 1 1 1 2 2 2 0 Mnd1 family DUF4200 PF13863.1 KXX80786.1 - 8.6 6.3 21.1 10 6.1 12.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) MOZART1 PF12554.3 KXX80787.1 - 2.4e-26 90.9 1.1 3.1e-26 90.5 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.1 KXX80788.1 - 5.3e-24 83.7 2.7 5.3e-24 83.7 1.9 3.8 3 2 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 KXX80788.1 - 2.9e-15 56.1 20.2 2.9e-15 56.1 14.0 4.4 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KXX80788.1 - 1.7e-09 37.3 9.8 1.7e-09 37.3 6.8 4.2 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX80788.1 - 2.4e-07 30.6 8.0 2.4e-07 30.6 5.6 5.1 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX80788.1 - 3.7e-05 23.3 9.5 3.7e-05 23.3 6.6 6.0 4 2 2 6 6 6 1 zinc-RING finger domain Exo_endo_phos PF03372.18 KXX80789.1 - 6.7e-09 36.0 0.0 8.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L3 PF00297.17 KXX80790.1 - 1.9e-29 102.8 0.5 1.9e-29 102.8 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L3 LTXXQ PF07813.7 KXX80790.1 - 0.032 14.6 1.8 0.066 13.6 1.2 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein TMF_DNA_bd PF12329.3 KXX80790.1 - 0.062 13.1 2.9 0.1 12.4 2.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NifQ PF04891.7 KXX80790.1 - 0.15 12.1 0.8 0.26 11.4 0.6 1.3 1 0 0 1 1 1 0 NifQ DUF814 PF05670.8 KXX80791.1 - 3e-17 62.2 0.1 6.5e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF814) PITH PF06201.8 KXX80792.1 - 5.4e-47 159.3 0.0 6.5e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.4 KXX80793.1 - 5.8e-76 256.1 0.0 5.8e-75 252.8 0.0 2.3 1 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor Myc_N PF01056.13 KXX80793.1 - 0.0014 17.8 1.0 0.0025 17.0 0.7 1.3 1 0 0 1 1 1 1 Myc amino-terminal region CPSase_L_D2 PF02786.12 KXX80794.1 - 4.6e-81 271.1 0.3 7.3e-81 270.4 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KXX80794.1 - 3e-67 225.8 0.0 5.4e-67 225.0 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KXX80794.1 - 3.9e-32 110.6 0.1 7.9e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KXX80794.1 - 3.9e-31 107.2 0.0 9.5e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KXX80794.1 - 3.6e-25 88.9 0.0 7.4e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KXX80794.1 - 4.9e-21 75.3 0.2 1.1e-20 74.1 0.2 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KXX80794.1 - 8.5e-19 66.9 0.7 3e-18 65.2 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KXX80794.1 - 5.4e-16 58.2 0.1 4.5e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX80794.1 - 5.3e-11 42.2 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KXX80794.1 - 5.1e-10 38.8 0.4 6.1e-06 25.7 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 KXX80794.1 - 1.1e-07 31.3 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KXX80794.1 - 6.1e-06 25.8 0.0 3e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KXX80794.1 - 3.8e-05 23.6 0.0 9.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KXX80794.1 - 0.00032 20.1 0.1 0.0086 15.4 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KXX80794.1 - 0.0031 17.8 0.0 6.1 7.2 0.0 3.3 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 KXX80794.1 - 0.007 15.5 0.0 0.87 8.6 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 KXX80794.1 - 0.0096 15.4 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 KXX80794.1 - 0.029 14.0 0.1 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 KXX80794.1 - 0.12 12.0 0.2 0.8 9.3 0.0 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein p450 PF00067.17 KXX80795.1 - 1.3e-54 185.5 0.0 1.6e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L5_C PF00673.16 KXX80796.1 - 7.7e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KXX80796.1 - 2.3e-21 75.3 0.1 7e-21 73.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Pkinase PF00069.20 KXX80797.1 - 8.1e-30 103.8 0.0 1.3e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 KXX80797.1 - 1e-22 80.8 0.0 1.8e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 KXX80797.1 - 2.9e-15 56.0 0.0 4.3e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Coa1 PF08695.5 KXX80800.1 - 7.2e-39 131.9 0.0 9.6e-39 131.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1191 PF06697.7 KXX80801.1 - 0.011 14.6 0.4 0.015 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) RDD PF06271.7 KXX80801.1 - 0.061 13.2 1.2 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 RDD family DUF4231 PF14015.1 KXX80801.1 - 0.33 10.9 4.5 3 7.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DNA_pol_phi PF04931.8 KXX80802.1 - 1.6e-51 175.0 28.6 1.4e-34 119.0 15.1 3.3 2 1 0 2 2 2 2 DNA polymerase phi Vps35 PF03635.12 KXX80802.1 - 0.0014 16.9 0.4 0.027 12.6 0.3 2.4 2 1 0 3 3 3 1 Vacuolar protein sorting-associated protein 35 Proteasome PF00227.21 KXX80803.1 - 5.1e-47 159.6 2.3 7.3e-31 106.9 0.0 3.1 3 0 0 3 3 3 3 Proteasome subunit Proteasome_A_N PF10584.4 KXX80803.1 - 1.3e-11 43.5 0.9 1.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ecl1 PF12855.2 KXX80804.1 - 1.2e-08 34.0 2.5 2.3e-08 33.1 1.8 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 KXX80804.1 - 0.14 12.0 3.6 0.34 10.8 2.5 1.6 1 0 0 1 1 1 0 MYND finger zf-DNL PF05180.7 KXX80805.1 - 3.9e-27 93.7 0.1 6.2e-27 93.1 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KXX80805.1 - 0.0055 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger Msg2_C PF12373.3 KXX80805.1 - 0.021 14.0 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Elf1 PF05129.8 KXX80805.1 - 0.038 13.6 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PIH1 PF08190.7 KXX80805.1 - 0.053 12.9 3.1 0.071 12.5 2.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 zf-DNA_Pol PF08996.5 KXX80805.1 - 0.076 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger E7 PF00527.13 KXX80805.1 - 1.8 8.7 4.1 8.3 6.6 2.9 2.1 1 1 0 1 1 1 0 E7 protein, Early protein DRIM PF07539.7 KXX80806.1 - 4.1e-43 146.1 0.1 2e-42 143.9 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 KXX80806.1 - 3.8e-08 32.7 11.9 1.3 9.2 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KXX80806.1 - 0.0023 18.2 1.7 0.77 10.1 0.0 4.1 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KXX80806.1 - 0.15 12.6 12.9 1e+02 3.5 0.0 8.7 9 0 0 9 9 9 0 HEAT-like repeat CwfJ_C_2 PF04676.9 KXX80807.1 - 1.1e-24 86.7 0.8 2.3e-24 85.6 0.5 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KXX80807.1 - 1.7e-24 85.7 0.0 4.2e-24 84.5 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Rhodanese PF00581.15 KXX80808.1 - 9.8e-12 45.2 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cullin PF00888.17 KXX80810.1 - 1.2e-114 384.0 4.0 1.7e-114 383.5 2.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KXX80810.1 - 2e-27 94.7 0.6 6.6e-27 93.1 0.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.17 KXX80811.1 - 6e-18 64.1 0.0 8.1e-18 63.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 KXX80813.1 - 2.2e-12 46.6 0.0 2.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pox_ser-thr_kin PF05445.6 KXX80813.1 - 0.067 11.9 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_Tyr PF07714.12 KXX80813.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase AIG1 PF04548.11 KXX80814.1 - 0.034 13.2 0.4 0.083 11.9 0.0 1.9 2 0 0 2 2 2 0 AIG1 family MMR_HSR1 PF01926.18 KXX80814.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX80814.1 - 0.081 12.7 0.0 0.081 12.7 0.0 2.7 2 1 0 2 2 2 0 Dynamin family DUF4047 PF13256.1 KXX80814.1 - 0.32 10.9 8.5 0.64 9.9 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) 60KD_IMP PF02096.15 KXX80814.1 - 5.1 6.6 7.4 3.6 7.1 0.2 2.3 1 1 1 2 2 2 0 60Kd inner membrane protein DUF258 PF03193.11 KXX80815.1 - 9.3e-05 21.6 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KXX80815.1 - 0.00015 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KXX80815.1 - 0.029 13.4 0.1 0.072 12.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 KXX80815.1 - 0.038 13.4 1.5 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KXX80815.1 - 0.4 11.5 0.0 0.4 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KXX80815.1 - 0.5 10.1 0.1 0.5 10.1 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Effector_1 PF04518.7 KXX80815.1 - 0.59 9.0 5.9 4.7 6.0 1.0 2.1 2 0 0 2 2 2 0 Effector from type III secretion system DUF87 PF01935.12 KXX80815.1 - 0.67 9.7 0.0 0.67 9.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 ABC_tran PF00005.22 KXX80815.1 - 0.78 10.0 0.0 0.78 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Peptidase_C37 PF05416.7 KXX80815.1 - 1.8 6.7 12.6 0.017 13.4 3.4 1.4 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Nol1_Nop2_Fmu PF01189.12 KXX80816.1 - 4.2e-100 334.7 0.0 7.8e-100 333.8 0.0 1.4 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KXX80816.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KXX80816.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Clathrin PF00637.15 KXX80817.1 - 9.2e-202 660.7 42.7 2.4e-34 117.9 0.8 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KXX80817.1 - 9e-34 115.1 0.3 3.8e-33 113.1 0.2 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 KXX80817.1 - 4.5e-30 101.8 0.9 4.5e-06 26.5 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_7 PF13176.1 KXX80817.1 - 0.0003 20.3 9.6 2.9 7.9 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80817.1 - 0.0025 17.6 9.4 5 7.1 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Ank_5 PF13857.1 KXX80817.1 - 0.059 13.6 0.0 4.3 7.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TPR_14 PF13428.1 KXX80817.1 - 0.56 10.9 20.9 28 5.6 0.1 9.1 9 1 1 10 10 10 0 Tetratricopeptide repeat Clathrin-link PF09268.5 KXX80817.1 - 2.8 7.0 9.7 3 6.9 0.2 3.1 3 0 0 3 3 3 0 Clathrin, heavy-chain linker DUF1640 PF07798.6 KXX80818.1 - 3.1e-65 219.4 7.4 3.9e-65 219.2 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CLAMP PF14769.1 KXX80818.1 - 0.04 14.0 0.0 0.18 11.9 0.1 2.0 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Syntaxin PF00804.20 KXX80818.1 - 0.11 12.6 9.6 0.048 13.8 3.2 2.4 1 1 1 2 2 2 0 Syntaxin MPC PF03650.8 KXX80819.1 - 4.9e-33 113.6 0.0 5.8e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Cyto_heme_lyase PF01265.12 KXX80820.1 - 1.1e-78 264.4 0.0 1.3e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_S28e PF01200.13 KXX80822.1 - 4.5e-33 112.8 2.8 4.9e-33 112.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ABC1 PF03109.11 KXX80823.1 - 1.6e-26 92.6 0.0 3.2e-23 81.9 0.0 2.4 1 1 0 1 1 1 1 ABC1 family APH PF01636.18 KXX80823.1 - 0.019 14.7 1.4 0.043 13.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cu-oxidase_2 PF07731.9 KXX80824.1 - 1.1e-37 128.5 5.0 2e-37 127.7 0.1 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KXX80824.1 - 6e-36 122.7 6.6 8.6e-35 119.0 1.1 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 KXX80824.1 - 1.5e-35 122.4 0.0 2e-34 118.7 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase GCIP PF13324.1 KXX80825.1 - 2e-05 23.9 0.4 2e-05 23.9 0.3 2.6 3 1 1 4 4 4 1 Grap2 and cyclin-D-interacting BUD22 PF09073.5 KXX80825.1 - 0.00046 19.3 0.0 0.00075 18.6 0.0 1.3 1 0 0 1 1 1 1 BUD22 CobT PF06213.7 KXX80825.1 - 0.00051 19.2 1.6 0.00084 18.5 1.1 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Glypican PF01153.14 KXX80825.1 - 0.011 14.3 1.7 0.016 13.8 1.2 1.2 1 0 0 1 1 1 0 Glypican Sigma70_ner PF04546.8 KXX80825.1 - 0.25 10.9 3.5 0.55 9.8 2.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KXX80825.1 - 0.63 8.0 2.6 0.85 7.5 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TT_ORF2 PF02957.10 KXX80825.1 - 0.7 10.6 6.0 1.8 9.2 4.2 1.7 1 0 0 1 1 1 0 TT viral ORF2 NOA36 PF06524.7 KXX80825.1 - 1.7 7.7 6.1 2.4 7.3 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KXX80825.1 - 6.8 5.2 17.1 10 4.7 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DbpA PF03880.10 KXX80826.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_5 PF13893.1 KXX80826.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4243 PF14027.1 KXX80827.1 - 0.01 15.2 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) PRKCSH-like PF12999.2 KXX80828.1 - 7.7e-40 136.3 3.7 1.2e-23 83.5 0.1 3.0 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KXX80828.1 - 1.2e-31 109.2 0.5 1.2e-31 109.2 0.4 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KXX80828.1 - 2.8e-10 40.8 0.9 8e-10 39.3 0.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PspB PF06667.7 KXX80828.1 - 0.017 15.0 0.4 0.057 13.3 0.3 1.8 1 0 0 1 1 1 0 Phage shock protein B NPV_P10 PF05531.7 KXX80828.1 - 0.017 15.3 2.1 0.041 14.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Myb_DNA-bind_4 PF13837.1 KXX80828.1 - 0.063 13.4 1.3 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Filament PF00038.16 KXX80828.1 - 0.07 12.5 18.1 0.15 11.5 5.9 2.7 3 0 0 3 3 3 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 KXX80828.1 - 0.41 10.4 16.0 5.4 6.7 5.0 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 KXX80828.1 - 0.94 9.2 18.7 7.6 6.3 0.1 4.1 3 1 1 4 4 4 0 Prefoldin subunit MAD PF05557.8 KXX80828.1 - 2.6 6.0 17.5 0.49 8.4 9.8 1.3 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF3373 PF11853.3 KXX80828.1 - 4.5 5.7 7.6 4.3 5.7 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) PspA_IM30 PF04012.7 KXX80828.1 - 4.9 6.4 18.5 1.3 8.3 5.4 2.6 3 0 0 3 3 3 0 PspA/IM30 family DUF4200 PF13863.1 KXX80828.1 - 7.4 6.5 22.6 11 5.9 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) HAUS5 PF14817.1 KXX80828.1 - 9.7 4.5 14.0 21 3.4 9.8 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 Rtf2 PF04641.7 KXX80829.1 - 1.6e-49 168.4 0.0 2.1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KXX80829.1 - 7.3e-05 22.4 0.1 0.00016 21.2 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KXX80829.1 - 0.00013 21.6 0.1 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KXX80829.1 - 0.0029 17.4 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX80829.1 - 0.031 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX80829.1 - 0.038 14.0 0.3 0.07 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 KXX80829.1 - 1.1 9.0 4.0 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 MFS_1 PF07690.11 KXX80830.1 - 2.9e-25 88.7 33.7 2.9e-25 88.7 23.4 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX80830.1 - 1.3e-11 43.7 9.5 1.3e-11 43.7 6.6 3.3 3 2 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KXX80830.1 - 1.2e-07 30.3 2.0 1.2e-07 30.3 1.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UQ_con PF00179.21 KXX80831.1 - 3.4e-26 91.3 0.1 4.7e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tyr_Deacylase PF02580.11 KXX80832.1 - 2.8e-46 157.1 0.1 3.2e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FAT PF02259.18 KXX80833.1 - 3.3e-130 434.1 3.6 8.5e-130 432.8 2.5 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KXX80833.1 - 1.1e-62 211.5 0.4 2e-62 210.7 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KXX80833.1 - 1.1e-58 197.7 3.5 1.1e-57 194.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KXX80833.1 - 5e-43 145.2 2.5 8.3e-43 144.5 0.1 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 KXX80833.1 - 1.9e-18 64.8 12.1 0.0059 16.5 0.0 10.5 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 KXX80833.1 - 1.8e-17 63.3 8.7 0.00015 21.9 0.1 7.6 6 1 0 6 6 6 3 HEAT repeats FATC PF02260.15 KXX80833.1 - 3.3e-14 52.0 0.1 8.8e-14 50.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KXX80833.1 - 8.8e-14 51.5 5.1 0.0056 17.1 0.1 11.5 9 2 2 11 11 10 2 HEAT-like repeat Adaptin_N PF01602.15 KXX80833.1 - 3e-08 32.4 7.1 0.00033 19.1 0.1 4.3 3 2 2 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 KXX80833.1 - 0.00013 21.9 8.2 0.045 13.5 0.1 6.9 6 1 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KXX80833.1 - 0.00017 21.4 1.0 1.7 8.6 0.0 4.2 3 0 0 3 3 3 2 UME (NUC010) domain CLASP_N PF12348.3 KXX80833.1 - 0.00095 18.5 6.4 2 7.6 0.0 5.5 5 2 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KXX80833.1 - 0.0052 17.1 6.7 71 3.8 0.0 7.4 6 2 3 9 9 9 0 Vacuolar 14 Fab1-binding region AAA_27 PF13514.1 KXX80833.1 - 0.1 10.2 4.8 0.023 12.4 0.2 2.0 2 0 0 2 2 2 0 AAA domain Zn_peptidase_2 PF04298.7 KXX80834.1 - 0.027 13.8 0.1 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase ADH_zinc_N PF00107.21 KXX80835.1 - 1.6e-17 63.2 0.0 2.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX80835.1 - 1.6e-12 48.3 0.1 1.3e-11 45.5 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX80835.1 - 4.9e-09 35.9 0.0 2e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 4HBT_2 PF13279.1 KXX80837.1 - 8.4e-06 26.2 0.0 1.1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KXX80837.1 - 1.7e-05 24.8 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KXX80837.1 - 0.0001 21.3 0.7 0.00017 20.6 0.5 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase YqzH PF14164.1 KXX80837.1 - 0.11 12.3 0.4 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 YqzH-like protein Myosin_tail_1 PF01576.14 KXX80839.1 - 0.082 10.6 8.8 0.11 10.2 6.1 1.0 1 0 0 1 1 1 0 Myosin tail Leu_zip PF15294.1 KXX80839.1 - 0.084 11.9 5.7 0.11 11.5 4.0 1.1 1 0 0 1 1 1 0 Leucine zipper bZIP_1 PF00170.16 KXX80839.1 - 0.097 12.6 15.4 0.53 10.2 10.6 1.9 1 1 0 1 1 1 0 bZIP transcription factor FliT PF05400.8 KXX80839.1 - 0.19 12.1 9.3 0.26 11.7 6.2 1.4 1 1 0 1 1 1 0 Flagellar protein FliT IncA PF04156.9 KXX80839.1 - 0.23 11.0 6.5 0.33 10.5 4.5 1.1 1 0 0 1 1 1 0 IncA protein Drf_FH1 PF06346.7 KXX80839.1 - 2.1 7.8 15.7 4.2 6.8 10.9 1.4 1 1 0 1 1 1 0 Formin Homology Region 1 Atg14 PF10186.4 KXX80839.1 - 4.1 6.2 8.7 4.3 6.2 5.3 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PseudoU_synth_2 PF00849.17 KXX80840.1 - 4.3e-28 98.2 0.0 6.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KXX80840.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ub-Mut7C PF14451.1 KXX80840.1 - 0.046 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin TGS PF02824.16 KXX80840.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 TGS domain Auto_anti-p27 PF06677.7 KXX80840.1 - 0.17 11.6 0.2 0.43 10.3 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) UCR_Fe-S_N PF10399.4 KXX80841.1 - 0.68 9.1 8.4 2 7.6 5.8 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1 PF07690.11 KXX80842.1 - 1.7e-25 89.4 41.1 2.3e-21 75.9 7.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX80842.1 - 1.2e-06 27.1 11.4 7e-05 21.4 0.2 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein DUF2723 PF11028.3 KXX80842.1 - 0.048 13.1 5.0 0.066 12.6 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) Topoisom_I_N PF02919.10 KXX80843.1 - 0.59 9.3 2.7 1.1 8.5 1.9 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Peptidase_S49_N PF08496.5 KXX80843.1 - 1.1 9.0 5.4 2.4 7.9 3.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ABC2_membrane PF01061.19 KXX80844.1 - 4.9e-83 277.4 50.0 1.6e-52 177.7 16.2 4.9 4 1 1 5 5 5 3 ABC-2 type transporter PDR_CDR PF06422.7 KXX80844.1 - 2.9e-39 132.8 1.2 4.3e-32 109.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KXX80844.1 - 2.6e-34 118.4 0.0 7.1e-16 58.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KXX80844.1 - 9.3e-22 76.9 0.0 2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KXX80844.1 - 1.8e-07 30.7 0.0 0.00076 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX80844.1 - 1.9e-06 27.9 0.1 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KXX80844.1 - 2.7e-06 26.6 0.0 0.00014 21.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KXX80844.1 - 1.5e-05 24.9 0.0 0.026 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KXX80844.1 - 6.5e-05 22.3 0.3 0.023 14.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KXX80844.1 - 0.0003 20.3 0.2 0.0064 15.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KXX80844.1 - 0.00031 20.8 0.0 0.55 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KXX80844.1 - 0.0008 19.4 0.0 1.4 8.7 0.0 3.0 4 0 0 4 4 3 2 AAA domain ABC2_membrane_3 PF12698.2 KXX80844.1 - 0.0012 18.0 12.8 0.0012 18.0 8.9 3.3 3 2 0 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 KXX80844.1 - 0.0052 17.6 0.0 1.3 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KXX80844.1 - 0.0068 15.6 0.0 1.5 7.9 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KXX80844.1 - 0.0096 15.6 0.3 4.4 7.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KXX80844.1 - 0.014 15.0 0.2 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KXX80844.1 - 0.035 14.4 0.1 1.1 9.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 KXX80844.1 - 0.057 13.3 0.1 0.83 9.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 KXX80844.1 - 0.076 12.6 0.3 3.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Voltage_CLC PF00654.15 KXX80844.1 - 0.082 11.9 11.1 1 8.2 0.2 3.0 3 0 0 3 3 3 0 Voltage gated chloride channel AAA_10 PF12846.2 KXX80844.1 - 0.14 11.5 1.2 6.7 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KXX80844.1 - 0.15 12.5 0.0 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF3357 PF11837.3 KXX80844.1 - 0.15 11.9 0.8 2.2 8.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) AAA_23 PF13476.1 KXX80844.1 - 0.15 12.3 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Bac_surface_Ag PF01103.18 KXX80845.1 - 3.5e-41 141.7 0.3 4.6e-41 141.3 0.2 1.2 1 0 0 1 1 1 1 Surface antigen Sugar_tr PF00083.19 KXX80846.1 - 6.9e-85 285.2 17.2 7.9e-85 285.1 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX80846.1 - 1.2e-21 76.8 45.6 1.3e-20 73.4 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KXX80847.1 - 2.4e-21 75.6 1.2 5.1e-21 74.6 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX80847.1 - 4.3e-13 48.9 0.1 1e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like COesterase PF00135.23 KXX80848.1 - 6e-83 279.3 0.0 1.2e-82 278.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX80848.1 - 5.1e-09 36.0 0.2 1.5e-08 34.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX80848.1 - 0.0017 18.1 0.2 0.0035 17.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX80848.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KXX80848.1 - 0.33 9.5 0.0 7.9 5.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) RhgB_N PF09284.5 KXX80850.1 - 2e-117 390.9 4.4 3e-117 390.3 3.1 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KXX80850.1 - 1.9e-58 196.8 0.1 5.3e-58 195.3 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KXX80850.1 - 1.4e-16 60.3 1.7 3.8e-16 58.9 1.2 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KXX80850.1 - 6.3e-05 22.9 1.3 6.3e-05 22.9 0.9 3.2 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KXX80850.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Acylphosphatase PF00708.13 KXX80850.1 - 0.11 12.5 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Acylphosphatase Peptidase_M28 PF04389.12 KXX80851.1 - 1.4e-35 122.6 0.2 3.1e-35 121.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KXX80851.1 - 3.5e-08 33.1 0.0 5.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KXX80851.1 - 0.011 15.0 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 Nicastrin Aldo_ket_red PF00248.16 KXX80852.1 - 3e-47 160.7 0.0 4.4e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family RasGAP PF00616.14 KXX80853.1 - 1.7e-45 155.1 0.0 2.7e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KXX80853.1 - 4.6e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.18 KXX80855.1 - 1.3e-15 56.9 0.0 8.6e-15 54.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 KXX80855.1 - 3.2e-08 33.0 0.0 7.1e-07 28.6 0.0 2.7 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KXX80855.1 - 0.00023 20.8 6.4 0.00023 20.8 4.5 2.7 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C PF00271.26 KXX80855.1 - 0.11 12.3 0.0 0.37 10.6 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ureidogly_hydro PF04115.7 KXX80856.1 - 8.1e-49 165.1 0.0 1.2e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Mucin PF01456.12 KXX80856.1 - 0.08 12.7 18.9 0.13 12.0 13.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 KXX80856.1 - 0.18 9.4 3.9 0.22 9.2 2.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KXX80856.1 - 3.3 7.4 18.8 6 6.6 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_4 PF13894.1 KXX80857.1 - 0.24 11.8 0.1 0.24 11.8 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KXX80857.1 - 0.26 11.7 0.2 0.26 11.7 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Not3 PF04065.10 KXX80858.1 - 2.7e-99 331.1 25.3 2.7e-99 331.1 17.6 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KXX80858.1 - 3.1e-41 140.4 10.1 3.1e-41 140.4 7.0 2.3 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 KXX80858.1 - 2.7e-05 24.4 9.6 0.0005 20.3 0.1 2.6 2 0 0 2 2 2 1 Snapin/Pallidin DUF2373 PF10180.4 KXX80858.1 - 0.003 17.0 2.5 0.007 15.8 1.8 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KXX80858.1 - 0.011 15.6 11.7 0.017 15.0 1.1 3.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sec5 PF15469.1 KXX80858.1 - 0.014 15.0 12.4 0.15 11.7 2.0 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF1192 PF06698.6 KXX80858.1 - 0.017 14.9 2.9 0.017 14.9 2.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 KXX80858.1 - 0.035 14.1 0.4 0.035 14.1 0.3 2.8 2 1 0 2 2 1 0 Osmosensory transporter coiled coil Poty_PP PF08440.5 KXX80858.1 - 0.11 11.5 5.5 0.033 13.2 1.4 1.8 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 KXX80858.1 - 0.32 11.0 11.3 0.093 12.7 4.2 2.5 2 0 0 2 2 2 0 Syntaxin-like protein CorA PF01544.13 KXX80858.1 - 2.5 7.0 6.9 0.59 9.1 0.6 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Pro_isomerase PF00160.16 KXX80859.1 - 1.6e-46 158.3 0.2 2.4e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KXX80859.1 - 1.1e-08 34.5 7.0 3e-05 23.5 0.3 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KXX80859.1 - 1.5e-06 27.6 3.2 0.00028 20.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX80859.1 - 0.00014 21.2 0.9 0.00044 19.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX80859.1 - 0.0021 17.9 1.5 0.0063 16.4 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX80859.1 - 0.0044 17.5 3.6 0.0082 16.6 0.8 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX80859.1 - 0.0044 16.7 1.0 0.011 15.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX80859.1 - 0.0049 17.4 2.2 0.0049 17.4 1.5 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX80859.1 - 0.012 16.0 1.2 0.052 14.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX80859.1 - 0.028 14.7 2.6 0.068 13.5 1.6 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KXX80859.1 - 0.04 13.7 0.4 0.09 12.6 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Iso_dh PF00180.15 KXX80860.1 - 1.4e-69 234.7 0.0 1.7e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short_C2 PF13561.1 KXX80861.1 - 1.7e-22 80.3 0.0 2.3e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX80861.1 - 1.4e-20 73.9 0.8 2e-20 73.3 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX80861.1 - 2.8e-11 43.4 0.4 4.5e-11 42.7 0.3 1.2 1 0 0 1 1 1 1 KR domain PHD PF00628.24 KXX80865.1 - 1.8e-09 37.1 2.1 1.8e-09 37.1 1.4 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KXX80865.1 - 0.046 13.0 2.9 0.075 12.3 2.0 1.4 1 0 0 1 1 1 0 PHD-finger MMR_HSR1 PF01926.18 KXX80866.1 - 2.2e-11 43.7 0.0 3.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX80866.1 - 0.0036 17.1 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.8 KXX80866.1 - 0.015 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KXX80866.1 - 0.032 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 KXX80866.1 - 0.034 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PRP38 PF03371.10 KXX80869.1 - 4.6e-64 215.1 0.0 5.6e-64 214.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF1509 PF07420.6 KXX80869.1 - 1.7 7.8 12.4 2.5 7.2 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) AAA PF00004.24 KXX80870.1 - 1.1e-30 106.5 0.0 6.7e-16 58.6 0.0 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KXX80870.1 - 7.9e-11 41.5 0.3 0.0029 17.3 0.0 3.9 3 0 0 3 3 3 3 Part of AAA domain RuvB_N PF05496.7 KXX80870.1 - 2.3e-10 39.9 0.0 0.24 10.4 0.0 4.4 4 0 0 4 4 4 3 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KXX80870.1 - 2e-08 34.0 0.1 0.0039 16.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX80870.1 - 2.4e-08 34.1 1.9 0.077 13.1 0.1 5.5 3 3 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KXX80870.1 - 2.6e-08 34.7 6.9 0.00014 22.6 0.1 4.9 3 2 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KXX80870.1 - 7e-07 28.6 0.0 0.11 11.6 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KXX80870.1 - 1.7e-06 27.6 0.3 0.16 11.3 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Torsin PF06309.6 KXX80870.1 - 1.9e-06 27.7 0.0 0.34 10.7 0.0 3.3 3 0 0 3 3 3 2 Torsin AAA_16 PF13191.1 KXX80870.1 - 2.3e-06 27.7 1.7 0.32 10.9 0.0 5.0 4 1 1 5 5 5 1 AAA ATPase domain AAA_33 PF13671.1 KXX80870.1 - 0.00013 21.8 0.1 0.12 12.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KXX80870.1 - 0.00021 21.4 0.0 0.3 11.2 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.1 KXX80870.1 - 0.00056 20.2 6.2 0.21 11.8 0.0 4.8 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 KXX80870.1 - 0.0072 16.3 0.0 8.8 6.3 0.0 3.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 KXX80870.1 - 0.0081 16.1 1.6 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 KXX80870.1 - 0.028 13.9 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KXX80870.1 - 0.056 12.9 0.1 2.2 7.8 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain Pox_A32 PF04665.7 KXX80870.1 - 0.39 9.9 0.0 0.98 8.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein DUF848 PF05852.6 KXX80871.1 - 0.26 11.1 16.0 0.083 12.7 0.7 3.8 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Rsa3 PF14615.1 KXX80871.1 - 0.28 10.4 1.6 0.59 9.4 0.4 2.2 2 0 0 2 2 2 0 Ribosome-assembly protein 3 TMF_DNA_bd PF12329.3 KXX80871.1 - 0.51 10.1 14.5 0.12 12.1 0.3 3.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KXX80871.1 - 1.8 8.9 19.8 0.28 11.5 0.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF972) RRM_1 PF00076.17 KXX80872.1 - 0.033 13.8 0.0 0.098 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KXX80873.1 - 5e-52 175.5 0.0 5.7e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX80873.1 - 4.2e-18 65.9 0.0 5.9e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX80873.1 - 1.2e-05 24.6 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX80873.1 - 0.012 15.0 0.0 0.051 13.0 0.0 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PQ-loop PF04193.9 KXX80874.1 - 7.1e-15 54.2 5.9 7.8e-14 50.9 0.5 2.9 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 KXX80874.1 - 0.054 13.3 0.3 0.58 10.0 0.1 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4535 PF15054.1 KXX80874.1 - 0.084 12.2 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF3093 PF11292.3 KXX80874.1 - 0.42 10.4 3.5 0.59 9.9 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Ras PF00071.17 KXX80875.1 - 6.1e-44 149.2 0.1 7.7e-44 148.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX80875.1 - 8.3e-13 48.8 0.0 1.6e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX80875.1 - 4.6e-06 25.9 0.1 6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX80875.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Scytalone_dh PF02982.9 KXX80875.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase RNA_pol_Rpb1_6 PF04992.9 KXX80876.1 - 0.0061 16.3 0.2 0.062 13.0 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 hEGF PF12661.2 KXX80876.1 - 0.012 15.6 1.5 0.031 14.3 1.0 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 KXX80876.1 - 1.4 9.1 11.8 2.5 8.3 8.2 1.4 1 0 0 1 1 1 0 EGF-like domain CMS1 PF14617.1 KXX80878.1 - 2e-97 325.1 2.1 2.4e-97 324.9 1.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KXX80878.1 - 4.9e-09 35.9 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1752 PF08550.5 KXX80879.1 - 0.11 12.1 0.7 0.26 10.8 0.5 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Pkinase PF00069.20 KXX80881.1 - 9.6e-23 80.6 0.0 2.9e-22 79.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX80881.1 - 3.8e-10 39.2 0.4 0.00019 20.6 0.1 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KXX80881.1 - 0.0022 17.7 3.9 0.012 15.3 0.3 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX80881.1 - 0.0046 16.0 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KXX80881.1 - 0.079 11.9 0.0 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Kinase-like WaaY PF06176.6 KXX80881.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KXX80881.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amidase PF01425.16 KXX80882.1 - 2.6e-90 303.4 4.2 4.3e-51 174.1 4.0 2.2 2 0 0 2 2 2 2 Amidase DUF4336 PF14234.1 KXX80883.1 - 6.1e-15 55.1 0.0 1.1e-09 37.9 0.0 2.6 2 1 0 3 3 3 2 Domain of unknown function (DUF4336) WD40 PF00400.27 KXX80884.1 - 5e-26 89.6 10.2 4.1e-09 35.9 0.7 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KXX80884.1 - 0.0022 18.1 0.2 2.4 8.5 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 KXX80884.1 - 0.033 12.4 1.9 6.1 5.0 0.0 3.4 4 0 0 4 4 4 0 Cytochrome D1 heme domain DNA_pol_phi PF04931.8 KXX80884.1 - 8 4.0 6.5 12 3.5 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi MmgE_PrpD PF03972.9 KXX80885.1 - 1.2e-150 501.6 0.0 1.4e-150 501.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Carboxyl_trans PF01039.17 KXX80886.1 - 2.4e-140 468.1 0.0 3.5e-140 467.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KXX80886.1 - 0.016 14.4 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 KXX80887.1 - 1.4e-43 148.5 1.9 3.1e-43 147.4 1.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KXX80887.1 - 9e-30 103.5 0.1 2e-29 102.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KXX80887.1 - 3.9e-20 71.0 0.0 8.6e-20 70.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KXX80887.1 - 4e-14 53.0 3.5 4.3e-14 52.9 0.2 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KXX80887.1 - 0.021 14.2 0.3 0.082 12.2 0.2 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.23 KXX80888.1 - 2.7e-12 46.4 0.0 5.8e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.13 KXX80889.1 - 1e-13 51.0 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX80889.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 KXX80890.1 - 4.5e-08 32.6 6.2 8e-07 28.7 0.5 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.17 KXX80890.1 - 0.00091 19.1 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KXX80890.1 - 0.48 10.2 7.6 1.1 9.1 5.3 1.6 1 0 0 1 1 1 0 Ring finger domain Arabinose_Isome PF02610.10 KXX80890.1 - 0.61 8.9 0.0 1.1 8.1 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase UQ_con PF00179.21 KXX80891.1 - 5e-47 158.8 0.0 5.9e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX80891.1 - 7.3e-05 22.5 0.0 9.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KXX80891.1 - 0.0081 15.8 0.1 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KXX80891.1 - 0.04 13.7 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF834 PF05754.9 KXX80892.1 - 1.8 8.4 7.9 1.2 8.9 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF834) ADH_zinc_N PF00107.21 KXX80893.1 - 1.1e-10 41.1 0.0 2.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX80893.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KXX80893.1 - 0.061 14.2 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PI3Ka PF00613.15 KXX80894.1 - 2e-56 190.1 2.2 3.5e-56 189.3 1.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KXX80894.1 - 8e-46 156.4 0.1 2.3e-44 151.6 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KXX80894.1 - 1.6e-32 112.2 0.0 3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 KXX80895.1 - 6.3e-36 122.2 0.0 1.3e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KXX80895.1 - 7.6e-19 67.3 0.0 2.3e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE UPF0302 PF08864.5 KXX80895.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 UPF0302 domain ApbA PF02558.11 KXX80896.1 - 6.3e-19 67.9 0.0 9.1e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KXX80896.1 - 2.7e-14 53.2 0.0 4.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sas10_Utp3 PF04000.10 KXX80897.1 - 3e-16 59.3 2.8 3e-16 59.3 1.9 1.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Spectrin PF00435.16 KXX80897.1 - 0.076 13.3 2.0 0.48 10.7 0.7 2.1 2 0 0 2 2 2 0 Spectrin repeat FTO_CTD PF12934.2 KXX80897.1 - 0.091 12.3 0.8 0.17 11.4 0.6 1.3 1 0 0 1 1 1 0 FTO C-terminal domain DUF948 PF06103.6 KXX80897.1 - 0.67 9.8 3.6 0.46 10.3 0.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KXX80897.1 - 2 8.7 5.7 9 6.6 0.3 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF919 PF06034.6 KXX80897.1 - 2.4 7.8 4.9 0.77 9.4 0.2 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF972 PF06156.8 KXX80897.1 - 3.9 7.8 7.4 8.6 6.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Coq4 PF05019.8 KXX80898.1 - 7.1e-99 329.2 0.0 8.5e-99 328.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 KXX80899.1 - 1.5e-35 121.4 15.3 1.8e-35 121.1 10.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KXX80899.1 - 0.0097 16.1 2.4 0.012 15.8 1.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4615) EF-1_beta_acid PF10587.4 KXX80899.1 - 0.038 14.1 2.1 0.038 14.1 1.4 3.9 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region Imm35 PF15581.1 KXX80899.1 - 0.12 12.3 0.4 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 35 SURF1 PF02104.10 KXX80900.1 - 1.2e-69 234.4 0.0 1.5e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 KXX80901.1 - 4.6e-117 391.7 12.7 4.6e-117 391.7 8.8 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KXX80901.1 - 1.3e-09 38.1 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KXX80901.1 - 2.3e-05 24.4 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KXX80901.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.8 KXX80901.1 - 0.78 9.5 10.9 0.12 12.1 4.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.4 KXX80902.1 - 1.1e-09 38.7 9.9 1.3e-09 38.5 6.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KXX80902.1 - 1.8e-05 24.5 3.8 2.3e-05 24.1 2.1 1.6 1 1 1 2 2 2 2 CHCH domain GCK PF07802.6 KXX80902.1 - 0.0014 18.6 0.3 0.0026 17.8 0.1 1.4 1 1 0 1 1 1 1 GCK domain DUF759 PF05537.6 KXX80902.1 - 0.11 11.2 1.0 0.15 10.8 0.7 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) PAT1 PF09770.4 KXX80902.1 - 0.86 7.7 4.7 0.99 7.5 3.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KXX80902.1 - 8.6 6.1 6.4 11 5.8 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBX PF00789.15 KXX80903.1 - 8.4e-14 51.4 0.0 1.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF2763 PF10961.3 KXX80903.1 - 0.00013 22.3 0.0 0.00038 20.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) CAF-1_p150 PF11600.3 KXX80903.1 - 0.3 10.4 26.5 0.49 9.7 18.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 KXX80903.1 - 0.92 8.6 25.0 1.7 7.8 17.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 IncA PF04156.9 KXX80903.1 - 1.1 8.8 9.9 2 7.9 6.9 1.4 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 KXX80903.1 - 1.6 6.8 16.1 2.1 6.5 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDK5_activator PF03261.10 KXX80903.1 - 4.1 6.6 7.6 5.7 6.1 5.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 KXX80903.1 - 4.9 6.9 15.5 6.8 6.4 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KXX80903.1 - 7 4.7 19.3 9.1 4.3 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_13 PF13166.1 KXX80903.1 - 8.7 4.6 12.0 11 4.2 8.3 1.1 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 KXX80904.1 - 1.7e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX80904.1 - 0.0027 17.3 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX80904.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 KXX80904.1 - 4.4 5.2 5.7 5.5 4.9 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SET PF00856.23 KXX80905.1 - 1.7e-16 60.9 0.0 6.2e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 SET domain DnaJ PF00226.26 KXX80909.1 - 9.4e-27 92.5 4.0 1.4e-26 91.9 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KXX80909.1 - 1.1e-21 76.4 1.8 5.3e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Zn_clus PF00172.13 KXX80910.1 - 8.2e-08 32.0 11.7 1.5e-07 31.1 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX80910.1 - 6.7e-05 21.6 0.0 9.9e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.22 KXX80911.1 - 3.9e-59 199.2 0.0 5.2e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KXX80911.1 - 2.1e-24 85.5 0.0 4.1e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KXX80911.1 - 4e-16 58.8 2.8 4e-16 58.8 2.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KXX80911.1 - 1.9e-05 24.6 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KXX80911.1 - 0.00012 21.5 0.4 0.00034 20.1 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KXX80911.1 - 0.0071 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KXX80911.1 - 0.038 13.4 0.1 8.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thioredoxin PF00085.15 KXX80912.1 - 2.4e-64 213.5 0.1 6.4e-31 106.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KXX80912.1 - 5.1e-26 91.1 1.3 2.1e-25 89.1 0.4 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KXX80912.1 - 3.8e-21 75.3 0.0 2.6e-09 37.2 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX80912.1 - 1.5e-15 57.1 0.0 4.6e-06 26.6 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KXX80912.1 - 2.3e-14 53.1 0.1 3.2e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KXX80912.1 - 4.8e-09 35.9 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KXX80912.1 - 6.7e-07 28.9 0.8 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 KXX80912.1 - 1.3e-05 24.9 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 KXX80912.1 - 1.3e-05 25.2 0.3 0.57 10.1 0.1 3.7 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 KXX80912.1 - 2.5e-05 23.8 0.0 0.076 12.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KXX80912.1 - 3.1e-05 23.8 0.1 0.0081 15.9 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like domain HyaE PF07449.6 KXX80912.1 - 3.6e-05 23.5 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 KXX80912.1 - 0.00082 19.3 0.1 1.5 8.8 0.0 3.0 2 1 0 2 2 2 2 Glutaredoxin DSBA PF01323.15 KXX80912.1 - 0.016 14.7 1.4 5.7 6.4 0.1 3.6 3 1 1 4 4 4 0 DSBA-like thioredoxin domain TraF PF13728.1 KXX80912.1 - 0.027 13.9 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein DDE_Tnp_1_2 PF13586.1 KXX80912.1 - 0.037 14.2 0.0 0.74 10.0 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Ribosomal_S14 PF00253.16 KXX80913.1 - 2.5e-18 65.1 3.4 2.9e-18 64.9 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 KXX80913.1 - 0.93 9.6 4.6 7.8 6.6 0.5 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase zf-RING_2 PF13639.1 KXX80914.1 - 8.4e-09 35.1 2.0 8.4e-09 35.1 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KXX80914.1 - 3.9e-07 30.0 0.9 1e-06 28.7 0.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KXX80914.1 - 9.1e-07 28.4 0.1 1.6e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX80914.1 - 5.8e-06 25.9 0.7 5.8e-06 25.9 0.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX80914.1 - 6e-05 22.9 2.4 6e-05 22.9 1.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX80914.1 - 6.4e-05 22.5 0.8 6.4e-05 22.5 0.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KXX80914.1 - 0.0064 16.3 0.8 0.016 15.0 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 KXX80914.1 - 0.21 9.2 0.2 0.33 8.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 KXX80914.1 - 1.6 8.4 8.1 0.052 13.2 0.5 2.3 2 1 1 3 3 3 0 RING-type zinc-finger HSBP1 PF06825.7 KXX80915.1 - 6.8e-15 54.3 0.9 8e-15 54.1 0.6 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Apolipoprotein PF01442.13 KXX80915.1 - 0.019 14.4 0.1 0.022 14.3 0.1 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Matrilin_ccoil PF10393.4 KXX80915.1 - 0.025 13.9 0.7 0.38 10.1 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Corona_S2 PF01601.11 KXX80915.1 - 0.033 12.3 0.2 0.033 12.2 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1664 PF07889.7 KXX80915.1 - 0.05 13.3 0.2 0.06 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KXX80915.1 - 0.063 13.1 0.7 0.074 12.8 0.5 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Init_tRNA_PT PF04179.7 KXX80916.1 - 2.1e-149 498.2 0.0 2.6e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 KXX80917.1 - 3e-16 60.1 0.0 4.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX80917.1 - 2.9e-09 36.5 0.1 5.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KXX80917.1 - 9.7e-09 35.9 0.2 5.4e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KXX80917.1 - 4.4e-06 26.4 0.0 0.0008 19.0 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Baculo_p74 PF04583.7 KXX80917.1 - 0.041 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Fungal_trans PF04082.13 KXX80918.1 - 1.1e-36 126.0 0.0 1.5e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX80918.1 - 4.2e-07 29.7 10.5 7.1e-07 29.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLRV_ORF5 PF01690.12 KXX80918.1 - 2.2 7.3 11.2 3.5 6.6 7.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WSC PF01822.14 KXX80919.1 - 1.4e-75 249.2 67.6 2.8e-20 72.0 7.6 4.9 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.18 KXX80919.1 - 1e-23 84.0 0.1 2.3e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Peroxidase RSS_P20 PF11757.3 KXX80920.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like NAD_kinase PF01513.16 KXX80921.1 - 1.2e-69 234.2 0.0 1.8e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RWD PF05773.17 KXX80922.1 - 5e-23 81.1 0.0 8.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KXX80922.1 - 2e-20 72.3 38.3 3.9e-15 55.4 2.7 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KXX80922.1 - 0.00011 21.9 10.0 0.00011 21.9 7.0 3.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX80922.1 - 0.0015 18.5 11.1 0.0015 18.5 7.7 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX80922.1 - 0.0048 16.5 9.8 0.0048 16.5 6.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX80922.1 - 0.0063 16.2 5.3 0.0063 16.2 3.6 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KXX80922.1 - 0.0065 16.1 10.2 0.0065 16.1 7.1 3.9 2 1 1 3 3 3 1 zinc-RING finger domain DUF2011 PF09428.5 KXX80923.1 - 8.5e-22 77.4 21.7 2.5e-21 75.9 15.1 1.7 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) zf-HC2 PF13490.1 KXX80923.1 - 0.12 12.3 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative zinc-finger Ashwin PF15323.1 KXX80924.1 - 0.36 10.7 3.3 1.1 9.1 2.3 1.8 1 1 0 1 1 1 0 Developmental protein HAUS6_N PF14661.1 KXX80925.1 - 1.4e-63 214.5 4.0 2.3e-63 213.8 2.7 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4050 PF13259.1 KXX80925.1 - 0.012 15.4 0.4 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PfkB PF00294.19 KXX80926.1 - 1.1e-18 67.3 0.0 3.2e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pyr_redox_3 PF13738.1 KXX80927.1 - 1.8e-18 67.3 0.0 1.6e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX80927.1 - 1.5e-08 33.9 0.8 7.6e-07 28.3 0.1 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KXX80927.1 - 1.9e-06 26.3 0.0 0.00018 19.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KXX80927.1 - 3.2e-05 23.8 0.0 0.00022 21.1 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 KXX80927.1 - 0.0089 16.1 0.0 4.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 KXX80927.1 - 0.079 12.1 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KXX80927.1 - 0.11 11.3 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DNA_pol3_a_NI PF14480.1 KXX80927.1 - 0.22 11.1 0.0 0.45 10.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I ECH PF00378.15 KXX80928.1 - 2e-38 131.9 0.0 2.6e-28 98.7 1.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family PWI PF01480.12 KXX80929.1 - 7.9e-10 38.7 0.4 2e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.15 KXX80930.1 - 6.7e-12 44.6 8.0 6.7e-12 44.6 5.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Peptidase_M43 PF05572.8 KXX80931.1 - 6.6e-12 45.2 2.6 7.8e-12 45.0 1.2 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 KXX80931.1 - 4.8e-05 23.4 0.7 7.2e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KXX80931.1 - 0.0033 17.9 0.7 0.0077 16.7 0.5 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KXX80931.1 - 0.0041 17.0 2.1 0.016 15.1 1.4 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KXX80931.1 - 0.0072 16.0 0.1 0.011 15.4 0.1 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 KXX80931.1 - 0.012 15.1 0.7 0.017 14.6 0.4 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_62 PF03664.8 KXX80932.1 - 9.6e-143 474.1 6.0 1.1e-142 473.9 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF3638 PF12340.3 KXX80933.1 - 3.9e-96 320.4 0.0 6.5e-96 319.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KXX80933.1 - 2.2e-15 55.4 0.1 4.6e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PAP2 PF01569.16 KXX80935.1 - 3.7e-18 65.4 0.6 7e-18 64.5 0.4 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KXX80935.1 - 0.073 12.7 3.2 0.79 9.4 0.0 2.8 2 1 0 2 2 2 0 Divergent PAP2 family Alg14 PF08660.6 KXX80935.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like MARVEL PF01284.18 KXX80936.1 - 0.4 10.5 19.1 0.82 9.4 13.3 1.5 1 1 0 1 1 1 0 Membrane-associating domain EphA2_TM PF14575.1 KXX80936.1 - 2.1 8.7 0.0 2.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain EBP PF05241.7 KXX80937.1 - 2.4e-51 173.5 8.9 3.2e-50 169.8 6.1 1.9 1 1 0 1 1 1 1 Emopamil binding protein HlyIII PF03006.15 KXX80937.1 - 3.9 6.8 8.6 1 8.7 2.6 1.9 2 0 0 2 2 2 0 Haemolysin-III related PAN_4 PF14295.1 KXX80938.1 - 1.3e-20 72.8 21.1 7.6e-07 28.7 0.7 4.7 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 KXX80938.1 - 1.2e-13 50.6 6.1 0.0041 16.8 0.1 4.7 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.7 KXX80938.1 - 0.25 10.9 21.5 1.4 8.5 1.2 4.8 4 0 0 4 4 4 0 PAN-like domain DUF2823 PF11034.3 KXX80939.1 - 5.6e-34 116.0 9.9 6.2e-34 115.9 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) MT0933_antitox PF14013.1 KXX80939.1 - 0.23 11.5 5.3 5.7 7.1 2.4 2.2 1 1 0 2 2 2 0 MT0933-like antitoxin protein NDT80_PhoG PF05224.7 KXX80940.1 - 7.6e-39 133.6 0.0 2.3e-38 132.0 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.3 KXX80941.1 - 2.2e-162 540.7 0.0 5e-160 533.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KXX80941.1 - 1.3e-73 247.4 0.0 1.3e-73 247.4 0.0 1.8 2 0 0 2 2 1 1 N1221-like protein Neur_chan_memb PF02932.11 KXX80941.1 - 0.023 14.5 5.3 0.047 13.5 3.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 KXX80941.1 - 0.11 11.7 33.2 0.2 10.9 23.0 1.3 1 0 0 1 1 1 0 SprA-related family DUF4557 PF15101.1 KXX80941.1 - 0.69 9.7 18.0 1.3 8.8 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SAGA-Tad1 PF12767.2 KXX80941.1 - 0.82 9.2 21.3 3.8 7.1 13.6 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CAF-1_p150 PF11600.3 KXX80941.1 - 1.2 8.4 17.9 2.9 7.2 12.4 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WASH-7_C PF14746.1 KXX80941.1 - 2.8 7.5 8.2 5.9 6.4 5.7 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal AAA_23 PF13476.1 KXX80941.1 - 4 7.7 13.2 8.4 6.6 9.1 1.4 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.3 KXX80941.1 - 5.9 5.5 11.0 8.7 4.9 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Folate_carrier PF01770.13 KXX80941.1 - 9.2 4.6 5.3 15 3.9 3.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier ABC_tran PF00005.22 KXX80943.1 - 1.3e-48 164.7 0.0 5e-28 98.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX80943.1 - 8e-36 123.8 28.6 6.8e-29 101.1 7.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KXX80943.1 - 3.3e-13 50.2 2.2 2.6e-05 24.3 0.0 3.9 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KXX80943.1 - 1.8e-12 46.9 2.0 2.7e-05 23.5 0.7 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KXX80943.1 - 2.6e-08 34.0 2.4 0.0013 18.7 0.2 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KXX80943.1 - 1.6e-07 31.5 2.2 0.023 14.8 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KXX80943.1 - 2.1e-05 23.9 1.0 0.016 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KXX80943.1 - 2.6e-05 23.2 0.1 0.056 12.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 KXX80943.1 - 2.9e-05 24.5 0.5 0.16 12.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KXX80943.1 - 3.2e-05 23.1 0.2 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX80943.1 - 6.7e-05 23.3 0.5 0.083 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KXX80943.1 - 0.0001 22.2 0.2 0.25 11.3 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KXX80943.1 - 0.00027 20.7 0.0 0.45 10.1 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 KXX80943.1 - 0.00035 21.3 0.0 1.3 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KXX80943.1 - 0.00035 20.4 0.0 0.21 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KXX80943.1 - 0.0009 19.5 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KXX80943.1 - 0.0016 17.9 1.0 0.8 9.0 0.1 2.7 2 1 1 3 3 3 1 AAA-like domain AAA PF00004.24 KXX80943.1 - 0.002 18.3 0.6 0.87 9.7 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX80943.1 - 0.0021 17.5 1.7 0.099 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KXX80943.1 - 0.0025 17.5 2.1 2.1 8.0 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KXX80943.1 - 0.0027 17.2 0.1 0.91 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 KXX80943.1 - 0.0035 16.7 1.6 0.71 9.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KXX80943.1 - 0.0037 16.7 1.6 0.16 11.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 KXX80943.1 - 0.004 16.6 0.5 2.4 7.6 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KXX80943.1 - 0.0044 16.6 0.9 0.66 9.6 0.0 2.9 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 KXX80943.1 - 0.0062 16.7 0.0 1.4 9.1 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_14 PF13173.1 KXX80943.1 - 0.0065 16.3 0.4 0.7 9.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 KXX80943.1 - 0.011 15.3 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KXX80943.1 - 0.02 14.4 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.18 KXX80943.1 - 0.025 14.3 0.4 0.6 9.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.1 KXX80943.1 - 0.028 14.3 0.1 6 6.8 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 KXX80943.1 - 0.031 13.4 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 KXX80943.1 - 0.037 12.8 0.3 2 7.2 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain Zeta_toxin PF06414.7 KXX80943.1 - 0.04 12.9 0.1 5.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 KXX80943.1 - 0.041 13.6 1.2 4 7.1 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KXX80943.1 - 0.047 12.3 0.3 7.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 KXX80943.1 - 0.061 12.3 0.3 8.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 KXX80943.1 - 0.066 12.9 0.6 7.9 6.1 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 KXX80943.1 - 0.098 12.2 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KXX80943.1 - 0.18 11.6 1.6 0.58 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AMP-binding PF00501.23 KXX80944.1 - 0 1241.7 9.4 5.4e-86 288.5 0.2 6.5 5 1 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KXX80944.1 - 0 1309.5 0.0 4.2e-57 193.2 0.0 10.8 10 1 0 10 10 10 9 Condensation domain PP-binding PF00550.20 KXX80944.1 - 1.7e-73 242.8 5.9 4.8e-12 45.9 0.0 8.5 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX80944.1 - 4.6e-20 72.3 7.2 0.001 20.0 0.0 6.6 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KXX80944.1 - 1.2e-06 27.2 0.0 0.64 8.3 0.0 4.9 5 0 0 5 5 5 3 Transferase family DUF3658 PF12395.3 KXX80944.1 - 0.0076 15.7 0.9 1.3 8.6 0.0 4.3 5 0 0 5 5 5 1 Protein of unknown function DDE_Tnp_1_2 PF13586.1 KXX80944.1 - 0.044 13.9 0.6 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Metallophos_3 PF14582.1 KXX80944.1 - 3.1 6.8 0.0 5.5 6.0 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily RHH_3 PF12651.2 KXX80944.1 - 3.1 7.5 0.1 8.4 6.2 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain FAD_binding_4 PF01565.18 KXX80946.1 - 5e-12 45.4 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 KXX80946.1 - 3.8e-06 26.7 0.3 0.035 13.6 0.0 2.5 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FF PF01846.14 KXX80946.1 - 0.0089 15.9 0.6 0.038 13.9 0.2 2.2 2 0 0 2 2 2 1 FF domain HTH_38 PF13936.1 KXX80946.1 - 0.065 12.7 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain zf-C2H2 PF00096.21 KXX80947.1 - 6.7e-07 29.2 11.0 0.00033 20.8 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX80947.1 - 1.5e-06 28.0 11.5 0.00025 21.1 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KXX80947.1 - 0.00033 20.7 6.0 0.00047 20.2 1.2 2.5 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KXX80947.1 - 0.0024 18.0 22.2 0.0095 16.1 1.4 4.5 4 1 0 4 4 4 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 KXX80947.1 - 0.0097 16.0 0.2 0.0097 16.0 0.2 3.2 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-met PF12874.2 KXX80947.1 - 0.14 12.4 2.9 13 6.1 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KXX80947.1 - 0.46 10.6 4.8 1.4 9.1 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KXX80947.1 - 2.1 8.5 6.7 8.9 6.4 0.9 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Methyltransf_31 PF13847.1 KXX80948.1 - 1.4e-14 53.9 0.0 2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX80948.1 - 5.7e-13 49.1 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX80948.1 - 5.8e-13 49.3 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX80948.1 - 1.4e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80948.1 - 1.2e-10 41.6 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX80948.1 - 1.6e-09 38.1 0.0 2.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX80948.1 - 1.2e-08 34.9 0.0 2.4e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX80948.1 - 1.6e-06 27.5 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KXX80948.1 - 3.6e-06 26.3 0.0 5.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 KXX80948.1 - 6.7e-05 22.9 0.0 9.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_19 PF04672.7 KXX80948.1 - 0.0017 17.6 0.0 0.021 14.1 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl methyltransferase Methyltransf_32 PF13679.1 KXX80948.1 - 0.0035 17.0 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KXX80948.1 - 0.0043 16.1 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KXX80948.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.6 KXX80948.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 KXX80948.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 KXX80948.1 - 0.091 12.0 0.0 2.6 7.2 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain FmrO PF07091.6 KXX80948.1 - 0.16 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF4357 PF14267.1 KXX80949.1 - 0.2 11.2 2.0 0.35 10.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) HET PF06985.6 KXX80950.1 - 8e-24 84.3 0.0 1.5e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chorismate_bind PF00425.13 KXX80951.1 - 4.4e-47 160.5 0.0 1.2e-45 155.9 0.0 2.2 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KXX80951.1 - 6.4e-30 104.0 0.0 1.5e-28 99.5 0.0 2.4 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region HET PF06985.6 KXX80953.1 - 2.2e-32 112.1 0.1 3.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.26 KXX80954.1 - 6.5e-07 29.3 0.1 2.7e-06 27.3 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain NAD_binding_2 PF03446.10 KXX80955.1 - 9.4e-13 48.3 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KXX80955.1 - 4.3e-07 30.2 0.1 9.9e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KXX80955.1 - 0.0056 16.4 0.2 0.031 13.9 0.1 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KXX80955.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KXX80955.1 - 0.083 12.3 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_45 PF02015.11 KXX80957.1 - 3.4e-90 301.4 16.6 4e-90 301.2 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 RNA_pol_Rpb2_6 PF00562.23 KXX80958.1 - 1.3e-125 419.1 0.0 2.9e-125 418.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KXX80958.1 - 3.7e-53 179.4 0.0 1.5e-52 177.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KXX80958.1 - 7e-47 159.2 0.0 1.5e-46 158.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KXX80958.1 - 1.4e-30 105.3 0.1 3.1e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KXX80958.1 - 3.1e-25 87.8 0.1 8.3e-25 86.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 KXX80958.1 - 4.5e-23 80.7 0.2 1.3e-22 79.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KXX80958.1 - 3e-20 71.7 0.1 8.2e-20 70.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 V-ATPase_G PF03179.10 KXX80960.1 - 1.8e-26 92.5 20.1 2.1e-26 92.2 13.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YusW PF14039.1 KXX80960.1 - 0.0095 16.1 4.9 0.015 15.5 3.4 1.3 1 0 0 1 1 1 1 YusW-like protein RGS-like PF09128.6 KXX80960.1 - 0.096 12.1 2.7 0.12 11.9 1.9 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF3552 PF12072.3 KXX80960.1 - 0.11 11.7 20.6 0.029 13.6 7.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 KXX80960.1 - 0.17 11.6 23.2 0.18 11.6 6.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Asp-B-Hydro_N PF05279.6 KXX80960.1 - 0.44 10.3 12.2 0.52 10.1 8.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_11 PF13086.1 KXX80960.1 - 0.5 9.8 5.1 0.69 9.4 3.6 1.2 1 0 0 1 1 1 0 AAA domain DUF2870 PF11069.3 KXX80960.1 - 0.61 10.1 5.1 0.82 9.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2201_N PF13203.1 KXX80960.1 - 0.82 8.7 6.9 0.98 8.5 4.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP11 PF06644.6 KXX80960.1 - 1 8.7 9.5 1.3 8.4 6.6 1.0 1 0 0 1 1 1 0 ATP11 protein DUF3987 PF13148.1 KXX80960.1 - 1.3 7.4 11.9 1.6 7.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Atg14 PF10186.4 KXX80960.1 - 1.7 7.5 8.3 2 7.3 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 KXX80960.1 - 2.1 7.2 9.5 2.5 6.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 KXX80960.1 - 2.9 7.8 13.1 3.5 7.6 9.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 KXX80960.1 - 8.4 3.9 8.1 9.4 3.8 5.6 1.0 1 0 0 1 1 1 0 Ycf1 Ribosomal_L6e PF01159.14 KXX80960.1 - 8.9 6.6 11.2 2.2 8.5 5.0 1.7 1 1 1 2 2 2 0 Ribosomal protein L6e FAD_binding_4 PF01565.18 KXX80961.1 - 3.8e-25 87.9 1.3 7.6e-25 87.0 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Glyco_hydro_11 PF00457.12 KXX80961.1 - 0.015 14.6 0.9 0.071 12.4 0.6 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 11 Glyco_hydro_43 PF04616.9 KXX80963.1 - 2e-69 233.8 2.0 2.6e-69 233.5 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Reg_prop PF07494.6 KXX80963.1 - 0.014 15.3 1.4 3.8 7.8 0.0 3.9 4 0 0 4 4 4 0 Two component regulator propeller Ifi-6-16 PF06140.8 KXX80965.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Interferon-induced 6-16 family VPR PF00522.13 KXX80965.1 - 0.14 11.9 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 VPR/VPX protein DUF3816 PF12822.2 KXX80965.1 - 0.16 11.8 0.9 0.21 11.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) BTB_2 PF02214.17 KXX80966.1 - 1.7e-11 44.1 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KXX80966.1 - 0.0006 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.2 KXX80968.1 - 2.2e-38 132.4 5.7 2.5e-38 132.2 4.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX80968.1 - 1e-22 80.8 0.2 1.3e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX80968.1 - 7.4e-19 67.9 0.1 1.9e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX80968.1 - 4.9e-07 29.5 0.1 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 KXX80968.1 - 0.0096 15.5 0.1 0.2 11.2 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KXX80968.1 - 0.047 13.9 0.1 0.092 12.9 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 KXX80968.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 KXX80968.1 - 0.094 12.0 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) Ubie_methyltran PF01209.13 KXX80969.1 - 3.4e-10 39.4 0.0 6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KXX80969.1 - 7e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX80969.1 - 0.0028 17.9 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX80969.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF4149 PF13664.1 KXX80971.1 - 3.2e-21 75.2 0.2 4.7e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) CTNNBL PF08216.6 KXX80972.1 - 6.7e-35 118.9 0.0 2.5e-34 117.0 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Neurochondrin PF05536.6 KXX80972.1 - 0.0028 16.0 0.2 0.18 10.0 0.0 2.9 1 1 2 3 3 3 1 Neurochondrin HEAT_2 PF13646.1 KXX80972.1 - 0.0052 17.0 5.8 0.14 12.4 0.4 3.3 2 0 0 2 2 2 2 HEAT repeats Arm PF00514.18 KXX80972.1 - 0.096 12.5 0.8 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat GFA PF04828.9 KXX80973.1 - 2.6e-19 68.9 0.3 3.6e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme B_lectin PF01453.19 KXX80974.1 - 2.7e-19 69.1 5.3 1e-11 44.7 0.4 2.1 1 1 1 2 2 2 2 D-mannose binding lectin PQQ PF01011.16 KXX80974.1 - 0.0023 17.4 1.1 0.013 15.0 0.4 2.4 1 1 1 2 2 2 1 PQQ enzyme repeat DUF3564 PF12087.3 KXX80974.1 - 0.019 14.5 0.2 0.036 13.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3564) Peptidase_S3 PF00944.14 KXX80974.1 - 0.077 12.4 0.9 0.091 12.1 0.6 1.1 1 0 0 1 1 1 0 Alphavirus core protein PA14 PF07691.7 KXX80974.1 - 0.088 12.4 0.1 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 PA14 domain DUF1996 PF09362.5 KXX80975.1 - 1.1e-89 300.1 1.2 1.3e-89 299.8 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PQQ_2 PF13360.1 KXX80976.1 - 5.7e-14 52.1 7.2 5.4e-06 26.0 2.4 3.2 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KXX80976.1 - 2.7e-11 42.3 8.3 0.11 12.0 0.0 7.0 6 0 0 6 6 6 4 PQQ enzyme repeat PQQ_3 PF13570.1 KXX80976.1 - 1.9e-06 27.9 30.6 0.0084 16.3 0.4 8.3 8 0 0 8 8 8 4 PQQ-like domain ketoacyl-synt PF00109.21 KXX80977.1 - 3.9e-64 216.5 0.0 6.3e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KXX80977.1 - 3.4e-35 120.4 0.5 3.8e-34 117.0 0.3 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KXX80977.1 - 2.2e-26 92.9 0.0 3.3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 KXX80977.1 - 0.0011 17.9 0.1 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SpoVAD PF07451.6 KXX80977.1 - 0.0028 16.1 0.4 0.0049 15.3 0.1 1.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.5 KXX80977.1 - 0.0095 15.5 0.2 0.043 13.4 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF676 PF05057.9 KXX80977.1 - 0.15 11.3 0.1 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Microtub_assoc PF07989.6 KXX80978.1 - 0.015 15.0 13.2 0.048 13.4 9.2 1.9 1 1 0 1 1 1 0 Microtubule associated APG6 PF04111.7 KXX80978.1 - 0.36 9.8 5.8 0.55 9.2 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Adeno_100 PF02438.11 KXX80978.1 - 0.42 8.7 2.8 0.63 8.1 1.9 1.1 1 0 0 1 1 1 0 Late 100kD protein IncA PF04156.9 KXX80978.1 - 6.3 6.3 8.6 13 5.3 6.0 1.4 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 KXX80979.1 - 2.8e-15 56.6 0.2 4.7e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX80979.1 - 1.1e-05 25.1 0.4 2.8e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX80979.1 - 0.02 14.3 0.1 0.048 13.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 KXX80981.1 - 5e-19 68.1 0.9 9.1e-19 67.3 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX80981.1 - 1.6e-06 27.9 2.1 4.7e-06 26.4 1.5 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX80981.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.20 KXX80982.1 - 7.6e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX80982.1 - 4.2e-10 39.5 0.0 5.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX80982.1 - 0.0039 16.9 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX80982.1 - 0.0049 16.8 0.0 0.03 14.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Transferase PF02458.10 KXX80983.1 - 8e-37 126.6 0.0 3.6e-30 104.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family p450 PF00067.17 KXX80984.1 - 1.4e-58 198.5 0.0 5e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 DUF3099 PF11298.3 KXX80984.1 - 0.086 12.5 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Abhydrolase_6 PF12697.2 KXX80985.1 - 7.8e-20 71.7 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX80985.1 - 1.9e-18 66.6 0.0 4.5e-18 65.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KXX80985.1 - 5.9e-08 31.5 0.1 0.0036 15.8 0.1 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KXX80985.1 - 3.2e-05 23.2 0.0 0.0095 15.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KXX80985.1 - 6.5e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KXX80985.1 - 0.00026 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1996 PF09362.5 KXX80986.1 - 5.9e-77 258.4 1.9 7.1e-77 258.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3315 PF11776.3 KXX80987.1 - 0.048 13.1 0.4 0.084 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) ETX_MTX2 PF03318.8 KXX80988.1 - 0.58 9.6 5.1 0.91 9.0 3.6 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Amino_oxidase PF01593.19 KXX80989.1 - 1e-36 127.0 0.1 9.2e-21 74.4 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX80989.1 - 2.1e-12 46.8 0.1 4.4e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX80989.1 - 9.4e-06 24.7 0.1 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX80989.1 - 5.3e-05 22.2 0.1 8.7e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX80989.1 - 0.0001 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX80989.1 - 0.00013 22.0 0.0 0.014 15.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX80989.1 - 0.00051 18.6 0.1 0.00075 18.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KXX80989.1 - 0.0015 18.9 0.1 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX80989.1 - 0.0031 16.6 0.2 0.0045 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KXX80989.1 - 0.018 14.1 0.1 0.035 13.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Strep_67kDa_ant PF06100.6 KXX80989.1 - 0.022 13.1 0.0 0.034 12.4 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 KXX80989.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KXX80989.1 - 0.055 12.5 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DASH_Dam1 PF08653.5 KXX80989.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 GIDA PF01134.17 KXX80989.1 - 0.18 10.6 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HET PF06985.6 KXX80990.1 - 5.3e-26 91.4 0.1 9.6e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Toxin_18 PF08087.6 KXX80992.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Conotoxin O-superfamily HET PF06985.6 KXX80993.1 - 4.8e-27 94.8 0.0 8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Scs3p PF10261.4 KXX80995.1 - 3.1e-59 199.9 0.3 5.2e-59 199.1 0.2 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.4 KXX80995.1 - 4.2e-17 61.6 0.0 9.3e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Glyco_hydro_47 PF01532.15 KXX80996.1 - 4.1e-161 536.6 0.0 4.7e-161 536.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA_12 PF13087.1 KXX80997.1 - 1.8e-41 141.7 0.0 4.7e-41 140.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KXX80997.1 - 2.9e-40 137.5 0.1 2.9e-13 50.1 0.0 7.0 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KXX80997.1 - 1.7e-31 109.6 22.1 1.7e-27 96.5 0.0 6.4 5 1 0 5 5 4 1 AAA domain AAA_19 PF13245.1 KXX80997.1 - 3.5e-20 71.5 3.6 1.8e-07 30.8 0.0 5.3 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 KXX80997.1 - 4e-14 52.8 7.3 0.0022 18.1 0.0 7.8 6 3 0 6 6 6 3 AAA domain AAA_30 PF13604.1 KXX80997.1 - 1.3e-12 47.6 12.7 0.00053 19.6 0.0 7.0 6 0 0 6 6 6 4 AAA domain AAA_5 PF07728.9 KXX80997.1 - 5.9e-12 45.5 0.5 0.17 11.6 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX80997.1 - 6.4e-12 46.3 13.7 0.068 13.9 0.0 6.2 6 0 0 6 6 5 4 AAA domain Mg_chelatase PF01078.16 KXX80997.1 - 2.4e-09 36.6 0.6 0.052 12.6 0.0 4.9 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KXX80997.1 - 9e-08 31.7 0.0 0.83 9.0 0.0 4.5 4 0 0 4 4 4 3 IstB-like ATP binding protein RNA_helicase PF00910.17 KXX80997.1 - 4.8e-07 29.9 0.2 1.5 9.0 0.0 4.7 4 0 0 4 4 4 2 RNA helicase AAA_16 PF13191.1 KXX80997.1 - 9.2e-07 29.0 17.6 0.13 12.2 0.0 6.7 6 1 0 6 6 5 3 AAA ATPase domain Torsin PF06309.6 KXX80997.1 - 3.2e-06 27.0 0.0 4.7 7.1 0.0 4.5 4 0 0 4 4 4 1 Torsin AAA_10 PF12846.2 KXX80997.1 - 1.7e-05 24.4 5.3 7.2 5.9 0.1 6.3 5 1 1 6 6 6 0 AAA-like domain AAA_24 PF13479.1 KXX80997.1 - 2.4e-05 24.0 7.5 0.23 11.0 0.2 4.7 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KXX80997.1 - 8.5e-05 22.8 13.7 1.5 9.1 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_25 PF13481.1 KXX80997.1 - 0.0011 18.4 8.7 0.12 11.7 0.0 5.7 5 1 0 6 6 6 1 AAA domain ResIII PF04851.10 KXX80997.1 - 0.0013 18.5 1.4 0.81 9.4 0.0 4.4 4 1 0 5 5 5 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 KXX80997.1 - 0.01 15.5 3.3 26 4.4 0.1 4.5 4 0 0 4 4 4 0 NTPase AAA_33 PF13671.1 KXX80997.1 - 0.011 15.5 23.0 0.48 10.2 0.0 6.5 7 1 0 7 7 5 0 AAA domain KaiC PF06745.8 KXX80997.1 - 0.012 14.7 2.2 13 4.7 0.0 4.2 4 0 0 4 4 4 0 KaiC UvrD_C_2 PF13538.1 KXX80997.1 - 0.014 15.5 0.0 0.052 13.6 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SRP54 PF00448.17 KXX80997.1 - 0.025 14.0 2.1 0.43 9.9 0.0 3.5 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KXX80997.1 - 0.17 10.8 0.0 0.17 10.8 0.0 7.0 8 1 0 8 8 6 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KXX80997.1 - 0.17 11.5 3.8 40 3.8 0.0 4.4 4 0 0 4 4 4 0 NACHT domain ADK PF00406.17 KXX80997.1 - 2.1 8.1 6.1 36 4.1 0.0 3.9 4 0 0 4 4 3 0 Adenylate kinase MFS_1 PF07690.11 KXX80999.1 - 2.4e-20 72.5 84.0 1.4e-19 70.0 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YobH PF13996.1 KXX80999.1 - 0.025 14.4 5.3 0.036 13.9 0.6 2.7 2 0 0 2 2 2 0 YobH-like protein Methyltransf_2 PF00891.13 KXX81000.1 - 1.2e-29 103.2 0.0 1.7e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KXX81000.1 - 0.043 13.5 0.0 0.66 9.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KXX81000.1 - 0.16 11.0 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cellulase PF00150.13 KXX81001.1 - 4.7e-20 71.9 0.5 8.5e-20 71.1 0.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Clr5 PF14420.1 KXX81002.1 - 0.16 11.8 1.2 0.35 10.7 0.8 1.6 1 0 0 1 1 1 0 Clr5 domain HET PF06985.6 KXX81003.1 - 2.6e-22 79.4 0.0 5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KXX81004.1 - 6.7e-22 78.1 5.9 7.4e-19 68.2 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pectate_lyase_3 PF12708.2 KXX81005.1 - 1e-85 287.4 15.4 4.6e-70 236.2 6.4 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KXX81005.1 - 7.2e-08 31.7 0.1 0.0025 17.2 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KXX81005.1 - 0.05 13.3 7.6 0.033 13.9 3.5 2.1 2 1 0 2 2 2 0 Right handed beta helix region AMP-binding PF00501.23 KXX81007.1 - 4.2e-72 242.8 0.0 5.4e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX81007.1 - 2.6e-05 25.0 0.1 0.00012 22.9 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KXX81008.1 - 3.8e-81 272.6 0.2 2.8e-80 269.7 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KXX81008.1 - 4.6e-79 265.4 0.0 9.8e-79 264.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KXX81008.1 - 1.5e-48 165.1 0.0 2.7e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 KXX81008.1 - 8e-47 160.1 0.0 1.7e-46 158.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KXX81008.1 - 3.4e-44 150.6 0.0 1.5e-42 145.2 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein PS-DH PF14765.1 KXX81008.1 - 4.5e-44 150.7 0.0 7.8e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KXX81008.1 - 4e-35 121.1 0.9 8.9e-33 113.4 0.1 2.9 3 0 0 3 3 3 1 KR domain Ketoacyl-synt_C PF02801.17 KXX81008.1 - 4.1e-32 110.5 0.0 1e-31 109.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KXX81008.1 - 5.7e-32 110.9 0.5 8.9e-28 97.2 0.1 2.9 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 KXX81008.1 - 2.6e-12 46.7 0.0 1.6e-10 40.8 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KXX81008.1 - 6.8e-12 45.4 1.0 1.7e-05 24.9 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KXX81008.1 - 2.5e-09 37.3 0.0 7.2e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KXX81008.1 - 1.1e-06 28.7 0.1 1.5e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KXX81008.1 - 1.3e-05 24.0 0.0 9.4e-05 21.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KXX81008.1 - 0.00048 19.1 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.1 KXX81008.1 - 0.0039 18.1 0.0 0.016 16.1 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_11 PF08241.7 KXX81008.1 - 0.021 15.2 0.0 0.064 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81008.1 - 0.035 14.5 0.0 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81008.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81008.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CBFB_NFYA PF02045.10 KXX81008.1 - 1.9 9.1 2.0 5 7.7 1.4 1.7 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Toxin_29 PF08116.6 KXX81010.1 - 0.13 12.0 15.4 1.5 8.6 2.2 2.8 2 0 0 2 2 2 0 PhTx neurotoxin family Colipase-like PF15083.1 KXX81010.1 - 0.16 11.9 2.2 1.5 8.8 0.2 2.1 2 0 0 2 2 2 0 Colipase-like Colipase PF01114.13 KXX81010.1 - 8.4 5.9 9.5 12 5.4 0.5 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain BTB PF00651.26 KXX81011.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain DUF1399 PF07173.7 KXX81012.1 - 1.3e-23 83.8 1.1 2.9e-17 63.2 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Glyco_hydro_7 PF00840.15 KXX81013.1 - 5.5e-144 479.7 4.9 6.4e-144 479.5 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Tyrosinase PF00264.15 KXX81014.1 - 9.6e-06 25.9 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_2 PF00703.16 KXX81015.1 - 0.072 13.5 0.2 2.2 8.7 0.0 2.4 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 Ribosomal_S19e PF01090.14 KXX81016.1 - 0.16 11.4 0.1 0.37 10.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein S19e UCH PF00443.24 KXX81017.1 - 3.4e-40 137.8 0.0 5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KXX81017.1 - 1.9e-23 82.3 16.6 2.6e-20 72.2 0.9 3.3 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KXX81017.1 - 1.2e-18 67.5 0.0 2.3e-14 53.5 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KXX81017.1 - 1.4e-18 66.1 0.1 1.5e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Stc1 PF12898.2 KXX81017.1 - 0.14 12.2 9.4 3.6 7.6 0.9 3.8 2 2 1 3 3 3 0 Stc1 domain HORMA PF02301.13 KXX81018.1 - 1.7e-43 148.5 0.0 2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain DUF2411 PF10304.4 KXX81018.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Ank_2 PF12796.2 KXX81019.1 - 1.9e-13 50.5 0.0 2.4e-07 30.9 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX81019.1 - 4.7e-10 38.7 6.3 0.03 14.1 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KXX81019.1 - 1e-07 32.2 1.8 0.071 13.6 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81019.1 - 4.6e-05 23.2 3.1 5.5 7.5 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 KXX81019.1 - 0.0021 18.2 3.4 0.99 9.7 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) TRP PF06011.7 KXX81020.1 - 6.2e-148 493.0 30.2 7.6e-148 492.7 21.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX81020.1 - 4.8e-40 136.8 0.1 7.6e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 KXX81020.1 - 0.056 13.6 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 ML domain UPF0183 PF03676.9 KXX81020.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) zf-DHHC PF01529.15 KXX81020.1 - 1.1 8.6 8.6 3.5e+02 0.4 5.9 2.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase adh_short PF00106.20 KXX81021.1 - 2.9e-19 69.5 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81021.1 - 6.9e-13 48.9 0.0 9.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX81021.1 - 7.3e-07 29.3 0.0 1.2e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KXX81021.1 - 0.0074 15.4 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KXX81021.1 - 0.0076 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Cauli_VI PF01693.11 KXX81022.1 - 3.3e-33 113.4 12.0 1.8e-17 63.0 1.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KXX81022.1 - 9.6e-28 97.1 0.0 1.6e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KXX81022.1 - 0.17 11.7 0.2 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like Beta-lactamase PF00144.19 KXX81025.1 - 2.2e-38 132.0 0.1 4.5e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase Abhydrolase_6 PF12697.2 KXX81029.1 - 1.8e-14 54.1 2.0 2.8e-14 53.5 0.7 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX81029.1 - 4.7e-11 42.6 0.1 1.1e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KXX81029.1 - 3.6e-06 25.8 0.0 5.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KXX81029.1 - 1.3e-05 24.5 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KXX81029.1 - 0.00027 19.5 0.0 0.018 13.5 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 KXX81029.1 - 0.0013 18.1 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 KXX81029.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KXX81029.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KXX81029.1 - 0.11 12.0 0.3 0.38 10.2 0.2 1.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KXX81029.1 - 0.2 11.3 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Carb_bind PF10645.4 KXX81030.1 - 6.8e-12 44.9 6.6 1.4e-11 43.9 4.6 1.6 1 0 0 1 1 1 1 Carbohydrate binding zinc-ribbons_6 PF07191.7 KXX81030.1 - 0.046 13.5 0.9 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons Glyco_hydro_11 PF00457.12 KXX81032.1 - 2.3e-81 271.5 17.9 2.7e-81 271.2 12.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.13 KXX81034.1 - 2e-14 53.0 0.1 3.8e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81034.1 - 3.2e-06 26.9 12.3 6e-06 26.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KXX81035.1 - 6e-74 249.2 0.0 7.1e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KXX81036.1 - 1.7e-23 82.5 0.7 3.9e-23 81.4 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX81036.1 - 6e-23 80.6 0.7 1.7e-22 79.2 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Redoxin PF08534.5 KXX81036.1 - 0.013 14.9 0.3 2.2 7.8 0.1 2.3 1 1 1 2 2 2 0 Redoxin Methyltransf_18 PF12847.2 KXX81036.1 - 0.027 15.0 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KXX81036.1 - 0.034 14.1 0.3 0.057 13.4 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.7 KXX81036.1 - 0.048 14.1 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CopK PF11525.3 KXX81036.1 - 0.19 11.4 0.5 26 4.5 0.0 3.0 3 0 0 3 3 3 0 Copper resistance protein K GMC_oxred_N PF00732.14 KXX81037.1 - 1.2e-48 165.8 0.0 1.6e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX81037.1 - 2.3e-33 115.5 0.2 3.7e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KXX81037.1 - 0.0076 16.2 0.1 0.029 14.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX81037.1 - 0.0086 15.0 0.1 0.092 11.6 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KXX81037.1 - 0.042 13.7 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX81037.1 - 0.057 12.3 0.1 0.12 11.2 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX81037.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KXX81037.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KXX81037.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase EphA2_TM PF14575.1 KXX81038.1 - 0.0068 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 KXX81038.1 - 0.009 15.6 0.1 0.038 13.6 0.0 1.8 1 1 1 2 2 2 1 CD34/Podocalyxin family Herpes_gE PF02480.11 KXX81038.1 - 0.013 13.7 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KXX81038.1 - 0.055 12.7 1.0 0.18 11.1 0.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1191 PF06697.7 KXX81038.1 - 0.13 11.0 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Granulin PF00396.13 KXX81038.1 - 0.68 10.0 7.4 0.57 10.3 1.8 2.4 2 0 0 2 2 2 0 Granulin Atg14 PF10186.4 KXX81039.1 - 1.4e-21 76.7 0.0 2.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KXX81039.1 - 0.00059 18.9 3.1 0.035 13.1 0.0 2.4 3 0 0 3 3 3 1 Autophagy protein Apg6 DUF1996 PF09362.5 KXX81040.1 - 2.5e-90 302.2 0.8 2.9e-90 302.0 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lyase_1 PF00206.15 KXX81041.1 - 2.2e-88 296.4 0.0 3.1e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KXX81041.1 - 2e-27 95.0 0.6 5.6e-27 93.6 0.1 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal YPEB PF14620.1 KXX81041.1 - 0.0035 16.4 0.0 0.069 12.1 0.0 2.1 2 0 0 2 2 2 1 YpeB sporulation ATP-grasp_4 PF13535.1 KXX81042.1 - 3.1e-20 72.6 0.0 9.8e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KXX81042.1 - 8.5e-05 21.4 0.0 0.0093 14.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KXX81042.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KXX81042.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PALP PF00291.20 KXX81043.1 - 9.5e-22 77.5 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_31 PF13847.1 KXX81044.1 - 1.3e-20 73.5 0.0 2.6e-20 72.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81044.1 - 3.4e-16 59.8 0.0 1.1e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81044.1 - 1.8e-12 47.5 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81044.1 - 2.1e-12 47.3 0.0 5.5e-12 46.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81044.1 - 4.8e-08 32.8 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81044.1 - 2.3e-07 31.1 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81044.1 - 3.7e-07 29.5 0.0 7.6e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX81044.1 - 1.5e-06 27.6 0.0 3.8e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX81044.1 - 1.1e-05 25.4 0.0 3.7e-05 23.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX81044.1 - 4.2e-05 22.6 0.0 8.8e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 KXX81044.1 - 0.00048 19.2 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 KXX81044.1 - 0.00081 18.8 0.0 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 KXX81044.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KXX81044.1 - 0.0051 16.3 0.0 0.02 14.4 0.0 1.9 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 KXX81044.1 - 0.0052 15.8 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 KXX81044.1 - 0.0059 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 KXX81044.1 - 0.0067 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX81044.1 - 0.0095 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_3 PF01596.12 KXX81044.1 - 0.04 12.9 0.0 0.068 12.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 KXX81044.1 - 0.061 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 HTH_23 PF13384.1 KXX81044.1 - 0.071 12.7 0.0 0.44 10.2 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain Ferric_reduct PF01794.14 KXX81045.1 - 1.5e-18 67.1 17.8 5.5e-18 65.2 12.3 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KXX81045.1 - 3.8e-05 23.6 0.0 0.36 10.7 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KXX81045.1 - 0.00022 21.7 0.0 0.00064 20.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 KXX81045.1 - 0.00036 20.3 0.0 0.58 10.0 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain Hist_deacetyl PF00850.14 KXX81045.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain NifU_N PF01592.11 KXX81046.1 - 7.2e-53 177.8 0.0 9.2e-53 177.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain PTR2 PF00854.16 KXX81047.1 - 1.7e-23 83.0 4.8 3.7e-16 58.8 1.2 2.3 1 1 0 2 2 2 2 POT family Claudin_2 PF13903.1 KXX81047.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.8 4 1 1 5 5 5 0 PMP-22/EMP/MP20/Claudin tight junction Mating_C PF12737.2 KXX81048.1 - 0.033 13.0 3.5 0.038 12.8 2.4 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Kinesin PF00225.18 KXX81049.1 - 1.8e-114 381.9 0.0 2.7e-114 381.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 KXX81049.1 - 0.0075 16.0 2.3 0.019 14.7 1.6 1.6 1 0 0 1 1 1 1 Herpesvirus UL14-like protein zf-C2H2 PF00096.21 KXX81050.1 - 1.7e-06 28.0 3.4 0.0066 16.7 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX81050.1 - 0.00025 21.1 3.7 0.014 15.6 0.0 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX81050.1 - 0.0065 16.5 2.1 2.7 8.2 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF3752 PF12572.3 KXX81050.1 - 0.026 14.6 0.4 0.05 13.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) LIM PF00412.17 KXX81050.1 - 0.054 13.5 0.8 0.12 12.4 0.5 1.6 1 1 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 KXX81050.1 - 0.072 13.2 1.4 3.5 7.8 0.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KXX81050.1 - 0.5 10.3 3.1 4 7.4 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Peptidase_A4 PF01828.12 KXX81052.1 - 7.1e-20 70.9 0.5 1.3e-19 70.1 0.4 1.4 1 1 0 1 1 1 1 Peptidase A4 family Sugar_tr PF00083.19 KXX81054.1 - 1.3e-109 366.7 30.7 1.9e-109 366.2 21.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX81054.1 - 2.5e-22 79.0 37.5 8.2e-17 60.9 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KXX81054.1 - 0.038 12.3 39.0 0.18 10.1 9.1 3.7 3 1 0 3 3 3 0 MFS/sugar transport protein Lysis_S PF04971.7 KXX81054.1 - 2 8.1 7.0 0.19 11.4 0.4 2.7 3 0 0 3 3 3 0 Lysis protein S DUF3506 PF12014.3 KXX81056.1 - 1e-44 151.6 0.0 1.9e-43 147.5 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KXX81056.1 - 6.2e-11 41.8 0.8 1.1e-10 41.0 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX81056.1 - 2.4e-05 23.8 2.1 2.5e-05 23.7 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KXX81056.1 - 0.13 11.9 0.3 0.28 10.9 0.2 1.5 1 1 0 1 1 1 0 F-box-like domain Oxidored_molyb PF00174.14 KXX81057.1 - 1.4e-52 177.5 0.0 2.3e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KXX81057.1 - 1e-24 86.6 0.1 7.7e-15 54.6 0.0 3.2 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KXX81057.1 - 8.1e-14 51.1 0.0 1.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UbiA PF01040.13 KXX81058.1 - 2e-32 112.4 23.4 2.2e-32 112.3 15.8 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family IncA PF04156.9 KXX81059.1 - 5.9e-05 22.7 5.7 0.025 14.1 3.9 2.6 1 1 0 1 1 1 1 IncA protein DUF904 PF06005.7 KXX81059.1 - 0.00027 21.1 3.9 0.0071 16.6 0.2 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF904) TSC22 PF01166.13 KXX81059.1 - 0.0003 20.7 0.2 0.28 11.1 0.0 2.8 2 0 0 2 2 2 1 TSC-22/dip/bun family Baculo_PEP_C PF04513.7 KXX81059.1 - 0.00073 19.3 5.7 0.0069 16.2 1.5 2.7 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 KXX81059.1 - 0.0017 18.4 7.7 0.44 10.7 0.6 3.2 2 2 0 2 2 2 2 Syntaxin DUF3584 PF12128.3 KXX81059.1 - 0.0038 14.6 5.8 0.0054 14.1 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KXX81059.1 - 0.0044 15.5 2.1 0.15 10.5 0.1 2.1 1 1 0 2 2 2 1 AAA domain Pox_A_type_inc PF04508.7 KXX81059.1 - 0.0059 16.2 4.3 0.022 14.5 0.0 3.2 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 KXX81059.1 - 0.0077 15.4 5.4 0.057 12.5 1.2 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 KXX81059.1 - 0.011 15.7 2.7 3.8 7.5 0.0 3.6 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 KXX81059.1 - 0.022 14.5 10.7 0.88 9.4 0.4 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.4 KXX81059.1 - 0.028 14.2 1.7 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain ALIX_LYPXL_bnd PF13949.1 KXX81059.1 - 0.03 13.2 4.5 0.059 12.3 3.1 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Filament PF00038.16 KXX81059.1 - 0.041 13.3 5.0 1.1 8.5 3.5 2.3 1 1 0 1 1 1 0 Intermediate filament protein YlqD PF11068.3 KXX81059.1 - 0.08 12.9 3.6 1.8 8.5 0.1 2.7 2 0 0 2 2 2 0 YlqD protein DUF1664 PF07889.7 KXX81059.1 - 0.088 12.6 2.5 1.9 8.2 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 KXX81059.1 - 0.16 9.6 3.9 0.48 8.0 2.7 1.7 1 1 0 1 1 1 0 Myosin tail DivIVA PF05103.8 KXX81059.1 - 0.18 11.8 5.3 4.8 7.2 0.3 2.7 2 0 0 2 2 2 0 DivIVA protein TBPIP PF07106.8 KXX81059.1 - 0.26 10.8 4.3 5 6.6 0.2 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 KXX81059.1 - 0.3 9.9 6.1 10 4.9 4.2 2.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 End3 PF12761.2 KXX81059.1 - 0.38 10.3 4.2 0.47 10.0 0.2 2.5 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 TPR_MLP1_2 PF07926.7 KXX81059.1 - 0.4 10.4 7.3 1.6 8.4 0.4 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YscO PF07321.7 KXX81059.1 - 0.45 10.3 5.3 1.9 8.3 0.2 2.8 2 0 0 2 2 2 0 Type III secretion protein YscO DUF342 PF03961.8 KXX81059.1 - 0.54 8.6 3.7 0.52 8.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 KXX81059.1 - 0.75 8.3 5.5 0.81 8.2 0.3 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 KXX81059.1 - 1.2 9.0 9.2 4 7.3 1.7 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KXX81059.1 - 1.3 9.5 10.4 0.36 11.2 1.1 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) V-SNARE PF05008.10 KXX81059.1 - 2.8 8.1 6.3 1.2 9.3 0.3 3.2 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TMF_TATA_bd PF12325.3 KXX81059.1 - 3.5 7.3 7.2 3.1 7.5 0.1 3.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding HET PF06985.6 KXX81060.1 - 1.3e-25 90.1 0.0 1.5e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 KXX81061.1 - 0.028 14.5 1.4 0.059 13.5 1.0 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) WEMBL PF05701.6 KXX81063.1 - 0.00036 19.1 47.6 0.12 10.8 22.8 3.8 3 1 0 3 3 3 3 Weak chloroplast movement under blue light Phage_GP20 PF06810.6 KXX81063.1 - 0.007 15.8 5.0 0.007 15.8 3.5 4.4 3 2 2 5 5 4 1 Phage minor structural protein GP20 FlaC_arch PF05377.6 KXX81063.1 - 0.24 11.3 0.1 0.24 11.3 0.0 5.4 7 0 0 7 7 5 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 KXX81063.1 - 0.34 10.7 46.9 0.046 13.5 4.9 4.8 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KXX81063.1 - 0.43 9.7 26.6 1.1 8.3 0.3 3.9 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KXX81063.1 - 0.49 8.0 46.5 0.059 11.0 20.9 2.5 3 0 0 3 3 3 0 Myosin tail APG6 PF04111.7 KXX81063.1 - 0.56 9.1 34.9 0.07 12.1 7.6 4.3 3 1 1 4 4 4 0 Autophagy protein Apg6 Spc7 PF08317.6 KXX81063.1 - 0.79 8.3 36.2 0.033 12.8 2.9 4.6 3 1 2 5 5 5 0 Spc7 kinetochore protein TBPIP PF07106.8 KXX81063.1 - 1.4 8.4 29.1 0.5 9.8 2.3 5.0 3 1 2 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 KXX81063.1 - 2.1 8.2 38.4 0.76 9.6 8.1 5.2 3 1 2 5 5 5 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 KXX81063.1 - 2.1 7.5 37.9 1.1 8.3 3.4 5.1 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KXX81063.1 - 2.5 7.8 47.7 0.2 11.4 0.5 5.8 3 1 1 5 5 5 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.2 KXX81063.1 - 2.6 7.3 47.7 0.5 9.6 6.9 4.4 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.5 KXX81063.1 - 2.6 8.1 23.2 1.9 8.6 1.2 4.9 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family ERM PF00769.14 KXX81063.1 - 2.7 7.4 46.5 0.04 13.4 1.8 4.7 3 1 2 5 5 5 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 KXX81063.1 - 3.4 7.5 47.4 0.082 12.7 0.6 7.3 3 2 4 7 7 7 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 KXX81063.1 - 4.6 5.5 27.8 0.18 10.2 3.7 3.4 2 1 1 3 3 3 0 AAA domain Filament PF00038.16 KXX81063.1 - 8.3 5.7 37.2 5.3 6.4 6.3 4.1 3 1 1 4 4 4 0 Intermediate filament protein DnaJ PF00226.26 KXX81065.1 - 7.4e-11 41.6 0.3 1.3e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_C69 PF03577.10 KXX81065.1 - 0.025 13.4 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C69 DEAD PF00270.24 KXX81066.1 - 5e-42 143.2 0.0 5e-42 143.2 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX81066.1 - 2.3e-23 81.8 0.1 2.3e-23 81.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Suf PF05843.9 KXX81066.1 - 5.6 6.5 8.1 9.9 5.8 5.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3328 PF11807.3 KXX81067.1 - 1.8e-30 106.2 1.4 1.8e-30 106.2 1.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KXX81068.1 - 1.3e-38 132.9 1.2 1.5e-38 132.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NACHT PF05729.7 KXX81069.1 - 2.4e-09 37.0 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KXX81069.1 - 0.0059 16.3 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KXX81069.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 KXX81069.1 - 0.016 14.9 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KXX81069.1 - 0.02 15.0 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KXX81069.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 KXX81069.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein RAG2 PF03089.9 KXX81069.1 - 0.045 12.4 0.0 0.048 12.3 0.0 1.0 1 0 0 1 1 1 0 Recombination activating protein 2 AAA_22 PF13401.1 KXX81069.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 KXX81069.1 - 0.073 11.8 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase PIF1 PF05970.9 KXX81069.1 - 0.13 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase zf-C2H2 PF00096.21 KXX81070.1 - 0.23 11.8 3.9 0.64 10.4 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX81070.1 - 0.81 10.1 4.4 2 8.9 3.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Transaldolase PF00923.14 KXX81071.1 - 6.4e-44 150.2 0.0 7.8e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Lysine_decarbox PF03641.9 KXX81071.1 - 0.021 14.6 0.4 0.045 13.5 0.3 1.5 1 0 0 1 1 1 0 Possible lysine decarboxylase DUF4360 PF14273.1 KXX81073.1 - 1e-12 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Abhydrolase_6 PF12697.2 KXX81074.1 - 1e-16 61.5 8.2 1.9e-16 60.6 3.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX81074.1 - 4.1e-08 33.0 0.2 6.9e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KXX81074.1 - 0.0003 20.4 0.1 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.15 KXX81074.1 - 0.00076 19.7 0.1 0.0012 19.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KXX81074.1 - 0.00088 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KXX81074.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 KXX81074.1 - 0.097 12.2 0.1 0.097 12.2 0.1 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF2305 PF10230.4 KXX81074.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 KXX81074.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CoaE PF01121.15 KXX81074.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase Cupin_2 PF07883.6 KXX81075.1 - 2.2e-11 43.0 0.3 3.7e-11 42.3 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KXX81075.1 - 2e-06 27.3 0.0 2.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KXX81075.1 - 0.003 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KXX81075.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) He_PIG PF05345.7 KXX81076.1 - 0.53 10.3 3.7 0.14 12.1 0.5 1.6 2 0 0 2 2 2 0 Putative Ig domain Myb_DNA-bind_6 PF13921.1 KXX81077.1 - 7.2e-07 29.2 1.0 9.2e-06 25.6 0.1 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KXX81077.1 - 0.0015 18.5 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain HET PF06985.6 KXX81079.1 - 7.5e-25 87.7 0.1 1.3e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1011 PF06237.7 KXX81080.1 - 0.25 11.2 1.8 0.56 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF4131 PF13567.1 KXX81080.1 - 0.76 9.1 2.9 2.1 7.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3784 PF12650.2 KXX81080.1 - 3.5 7.6 6.9 0.27 11.1 0.5 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF3784) Amidase PF01425.16 KXX81084.1 - 3e-53 181.2 0.1 1.1e-51 176.1 0.1 2.2 1 1 0 1 1 1 1 Amidase DUF3328 PF11807.3 KXX81085.1 - 4.6e-41 140.8 6.6 5.9e-39 134.0 4.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acyl_transf_3 PF01757.17 KXX81086.1 - 1.4e-31 109.5 24.3 2.2e-31 108.9 16.8 1.3 1 0 0 1 1 1 1 Acyltransferase family zf-UBR PF02207.15 KXX81087.1 - 0.16 11.6 1.3 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF3328 PF11807.3 KXX81089.1 - 4.3e-34 118.0 0.0 4.9e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) VPS9 PF02204.13 KXX81092.1 - 8e-24 83.6 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sec8_exocyst PF04048.9 KXX81092.1 - 0.097 12.3 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain K_oxygenase PF13434.1 KXX81092.1 - 0.34 9.7 1.3 0.89 8.4 0.8 1.8 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) VPS9 PF02204.13 KXX81093.1 - 8.3e-24 83.6 0.0 1.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sec8_exocyst PF04048.9 KXX81093.1 - 0.1 12.2 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain K_oxygenase PF13434.1 KXX81093.1 - 0.32 9.8 1.1 0.82 8.5 0.6 1.8 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_3 PF01764.20 KXX81094.1 - 2.4e-07 30.4 0.0 4.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KXX81094.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KXX81094.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_C50 PF03568.12 KXX81095.1 - 5.3e-109 364.4 0.0 8e-109 363.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KXX81095.1 - 5.3e-05 23.0 0.3 5.3e-05 23.0 0.2 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat AP_endonuc_2_N PF07582.7 KXX81096.1 - 0.16 11.5 0.2 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus SIR2 PF02146.12 KXX81097.1 - 5.6e-28 97.8 0.0 9.6e-28 97.1 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 KXX81098.1 - 1.4e-58 198.2 0.3 1.8e-58 197.9 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF808 PF05661.7 KXX81098.1 - 0.093 11.5 1.1 0.12 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF808) LpxK PF02606.9 KXX81099.1 - 0.048 12.6 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase NACHT PF05729.7 KXX81101.1 - 0.00035 20.2 0.2 0.00075 19.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain YPEB PF14620.1 KXX81101.1 - 0.0034 16.4 1.2 0.0054 15.7 0.4 1.5 1 1 0 1 1 1 1 YpeB sporulation AAA_22 PF13401.1 KXX81101.1 - 0.024 14.7 0.0 0.097 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KXX81101.1 - 0.31 10.8 1.8 24 4.7 0.1 3.0 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus cwf21 PF08312.7 KXX81101.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.1 3 0 0 3 3 3 0 cwf21 domain F-box-like PF12937.2 KXX81102.1 - 8.8e-09 34.9 0.3 0.0016 18.1 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KXX81102.1 - 1.7e-07 30.6 7.3 0.0018 17.8 0.0 3.0 3 0 0 3 3 3 2 F-box domain Sugar_tr PF00083.19 KXX81104.1 - 3.4e-73 246.7 24.7 4.2e-73 246.4 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX81104.1 - 8.3e-24 83.9 30.1 8.3e-24 83.9 20.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MerR-DNA-bind PF09278.6 KXX81104.1 - 0.13 12.6 0.5 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 MerR, DNA binding PLAC8 PF04749.12 KXX81105.1 - 4.5e-21 75.4 11.9 5.6e-21 75.0 8.2 1.1 1 0 0 1 1 1 1 PLAC8 family SH3_3 PF08239.6 KXX81106.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.8 KXX81106.1 - 0.0081 15.6 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial SH3 domain MT0933_antitox PF14013.1 KXX81107.1 - 1.4 9.0 8.9 6.2 7.0 6.1 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein AP_endonuc_2_N PF07582.7 KXX81109.1 - 0.16 11.5 0.2 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Prothymosin PF03247.9 KXX81110.1 - 0.11 12.5 13.1 0.62 10.2 2.3 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF572 PF04502.8 KXX81110.1 - 0.41 9.8 6.9 0.53 9.4 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PBP1_TM PF14812.1 KXX81110.1 - 1.6 9.0 10.5 6.4 7.1 3.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KXX81110.1 - 2.3 7.8 6.0 4 7.1 0.3 2.1 2 0 0 2 2 2 0 FAM176 family CorA PF01544.13 KXX81111.1 - 5.7e-08 32.1 3.5 5.7e-08 32.1 2.5 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein HLH PF00010.21 KXX81111.1 - 0.05 13.3 0.6 0.71 9.6 0.0 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF948 PF06103.6 KXX81111.1 - 0.37 10.6 3.3 2.3 8.1 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Rer1 PF03248.8 KXX81112.1 - 2.7e-81 271.3 5.6 3.1e-81 271.1 3.9 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 KXX81113.1 - 1.3e-71 240.5 0.2 1.6e-71 240.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KXX81113.1 - 0.0038 17.3 0.1 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region zf-C3HC4 PF00097.20 KXX81114.1 - 1.1e-07 31.3 3.2 1.1e-07 31.3 2.2 6.1 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX81114.1 - 2.8e-07 30.4 1.9 2.8e-07 30.4 1.3 5.9 4 4 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KXX81114.1 - 5.5e-05 22.8 0.7 5.5e-05 22.8 0.5 3.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 KXX81114.1 - 0.00015 21.2 0.2 0.00015 21.2 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KXX81114.1 - 0.00024 20.4 0.0 0.00062 19.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX81114.1 - 0.016 14.6 0.5 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Rer1 PF03248.8 KXX81115.1 - 2.7e-81 271.3 5.6 3.1e-81 271.1 3.9 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 KXX81116.1 - 1.3e-71 240.5 0.2 1.6e-71 240.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KXX81116.1 - 0.0038 17.3 0.1 0.0095 16.0 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region zf-C3HC4 PF00097.20 KXX81117.1 - 1.1e-07 31.3 3.2 1.1e-07 31.3 2.2 6.1 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX81117.1 - 2.8e-07 30.4 1.9 2.8e-07 30.4 1.3 5.9 4 4 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KXX81117.1 - 5.5e-05 22.8 0.7 5.5e-05 22.8 0.5 3.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 KXX81117.1 - 0.00015 21.2 0.2 0.00015 21.2 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KXX81117.1 - 0.00024 20.4 0.0 0.00062 19.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KXX81117.1 - 0.016 14.6 0.5 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Lipase_3 PF01764.20 KXX81118.1 - 2.4e-07 30.4 0.0 4.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KXX81118.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KXX81118.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_C50 PF03568.12 KXX81119.1 - 5.3e-109 364.4 0.0 8e-109 363.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KXX81119.1 - 5.3e-05 23.0 0.3 5.3e-05 23.0 0.2 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat SIR2 PF02146.12 KXX81120.1 - 5.6e-28 97.8 0.0 9.6e-28 97.1 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 KXX81121.1 - 1.4e-58 198.2 0.3 1.8e-58 197.9 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF808 PF05661.7 KXX81121.1 - 0.093 11.5 1.1 0.12 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF808) LpxK PF02606.9 KXX81122.1 - 0.048 12.6 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase CPDase PF07823.6 KXX81125.1 - 4.8e-28 98.0 0.0 7.7e-13 48.3 0.0 2.0 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KXX81125.1 - 0.016 14.9 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily WD40 PF00400.27 KXX81126.1 - 7.6e-18 63.6 2.9 7.6e-14 50.9 0.3 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.7 KXX81127.1 - 5.8e-10 39.0 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX81127.1 - 1.2e-07 31.9 0.2 1.2e-07 31.9 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KXX81127.1 - 1.6e-06 27.1 0.0 2.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KXX81127.1 - 0.0013 18.9 0.2 0.047 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX81127.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KXX81127.1 - 0.014 15.0 0.1 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KXX81127.1 - 0.014 14.3 0.7 0.059 12.3 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 KXX81127.1 - 0.022 15.0 0.1 0.066 13.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain Med9 PF07544.8 KXX81127.1 - 0.052 13.2 0.1 0.18 11.5 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_17 PF13207.1 KXX81127.1 - 0.06 14.1 0.3 0.32 11.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain Fez1 PF06818.10 KXX81127.1 - 0.066 13.2 1.1 0.099 12.6 0.7 1.2 1 0 0 1 1 1 0 Fez1 NPV_P10 PF05531.7 KXX81127.1 - 0.067 13.4 0.9 5.1 7.4 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RNA_helicase PF00910.17 KXX81127.1 - 0.095 12.8 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KXX81127.1 - 0.097 12.8 0.1 0.54 10.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 KXX81127.1 - 0.13 11.7 0.1 0.32 10.3 0.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mnd1 PF03962.10 KXX81127.1 - 0.14 11.8 0.2 0.3 10.7 0.1 1.5 1 1 0 1 1 1 0 Mnd1 family DUF2306 PF10067.4 KXX81129.1 - 0.0093 16.0 2.4 0.0093 16.0 1.7 2.8 2 1 1 3 3 3 1 Predicted membrane protein (DUF2306) Cytochrom_B561 PF03188.11 KXX81129.1 - 0.025 14.3 10.5 0.43 10.4 7.7 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Adeno_E3 PF06040.6 KXX81129.1 - 0.34 10.8 2.4 11 6.0 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF805 PF05656.9 KXX81129.1 - 0.97 9.2 15.1 1.5 8.6 1.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF805) Ni_hydr_CYTB PF01292.15 KXX81129.1 - 1.3 8.4 12.7 6.5 6.1 8.0 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 UPF0104 PF03706.8 KXX81129.1 - 9.2 5.4 19.3 0.63 9.2 3.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) WaaY PF06176.6 KXX81130.1 - 0.0042 16.3 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Chromo PF00385.19 KXX81131.1 - 0.032 13.8 0.3 0.08 12.6 0.2 1.7 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Adaptin_N PF01602.15 KXX81134.1 - 3.3e-103 345.8 0.0 3.9e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KXX81134.1 - 1.2e-10 41.5 10.8 8.8e-06 25.9 0.0 5.1 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KXX81134.1 - 7.3e-08 31.8 2.0 0.02 14.9 0.0 5.6 7 0 0 7 7 6 2 HEAT repeat HEAT_EZ PF13513.1 KXX81134.1 - 4.3e-06 27.0 7.4 0.013 15.9 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat Nop14 PF04147.7 KXX81134.1 - 0.00053 18.0 41.6 0.00082 17.4 28.9 1.2 1 0 0 1 1 1 1 Nop14-like family Cnd1 PF12717.2 KXX81134.1 - 0.0035 17.2 0.0 0.042 13.7 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KXX81134.1 - 0.0036 17.2 1.3 0.3 11.0 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion RR_TM4-6 PF06459.7 KXX81134.1 - 0.52 10.1 27.4 0.9 9.3 19.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 KXX81134.1 - 1.9 7.8 43.1 3.1 7.1 29.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 KXX81134.1 - 1.9 6.8 35.2 3.4 6.0 24.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pilt PF15453.1 KXX81134.1 - 2 8.0 19.4 4.3 6.9 13.4 1.6 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CENP-T PF15511.1 KXX81134.1 - 3.1 6.9 30.6 0.54 9.4 18.3 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Nuf2 PF03800.9 KXX81136.1 - 1.1e-45 155.2 0.3 1.1e-44 152.0 0.0 2.6 2 0 0 2 2 2 1 Nuf2 family V_ATPase_I PF01496.14 KXX81136.1 - 1.9 6.2 29.7 3.1 5.5 20.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_27 PF13514.1 KXX81136.1 - 3 5.4 49.6 12 3.4 34.1 1.8 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KXX81136.1 - 3.9 6.5 12.0 1.2 8.2 3.4 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein p450 PF00067.17 KXX81139.1 - 5.5e-35 120.7 0.0 6.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX81140.1 - 3.9e-09 35.5 0.0 4e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 KXX81141.1 - 2.5e-08 33.3 0.1 3.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KXX81141.1 - 2.7e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 KXX81141.1 - 0.085 12.4 0.1 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Cupin Cupin_3 PF05899.7 KXX81141.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) amfpi-1 PF12190.3 KXX81142.1 - 0.32 11.5 4.2 0.53 10.8 2.9 1.3 1 0 0 1 1 1 0 Fungal protease inhibitor MFS_1 PF07690.11 KXX81143.1 - 3.5e-47 160.8 42.8 3.5e-47 160.8 29.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX81143.1 - 3.6e-15 55.4 10.6 3.6e-15 55.4 7.3 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter eIF-1a PF01176.14 KXX81144.1 - 2.1e-14 52.7 0.0 3.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAD PF12710.2 KXX81145.1 - 3.7e-16 59.8 0.0 5.3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KXX81145.1 - 0.00024 21.3 0.0 0.00064 19.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KXX81145.1 - 0.00037 19.8 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 KXX81145.1 - 0.00045 19.4 0.0 0.0078 15.3 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 KXX81145.1 - 0.0028 18.1 0.5 0.26 11.6 0.0 3.1 1 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 KXX81145.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding UbiA PF01040.13 KXX81146.1 - 9.8e-21 74.1 16.5 1.2e-20 73.8 11.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NmrA PF05368.8 KXX81147.1 - 1.9e-18 66.6 0.0 2.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX81147.1 - 9.5e-13 48.5 0.0 2e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX81147.1 - 5.9e-06 25.5 0.0 8.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KXX81147.1 - 1.2e-05 24.8 0.3 0.00041 19.8 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX81147.1 - 0.00054 18.7 0.0 0.0014 17.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KXX81147.1 - 0.001 18.7 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX81147.1 - 0.027 14.3 0.2 0.045 13.6 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 KXX81147.1 - 0.034 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KXX81147.1 - 0.051 13.5 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus APH PF01636.18 KXX81148.1 - 3.4e-06 26.9 0.0 4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.9 KXX81149.1 - 2.6e-49 168.0 0.0 2.9e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.17 KXX81150.1 - 1.2e-32 113.0 0.0 1.5e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX81151.1 - 0.0012 17.4 0.0 0.0014 17.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX81153.1 - 1.9e-28 99.1 0.0 2.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DcpS_C PF11969.3 KXX81154.1 - 9.9e-13 48.3 5.6 1.1e-11 44.9 3.9 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KXX81154.1 - 2.3e-12 47.2 0.3 5.1e-12 46.1 0.2 1.5 1 1 0 1 1 1 1 HIT domain SnoaL_4 PF13577.1 KXX81155.1 - 3.2e-16 59.4 0.1 5.1e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KXX81155.1 - 0.00093 19.3 0.7 0.0017 18.5 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Type_III_YscX PF09474.5 KXX81155.1 - 0.13 12.3 0.1 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) IBN_N PF03810.14 KXX81156.1 - 1e-11 44.5 0.0 8.4e-10 38.4 0.0 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 KXX81156.1 - 0.00021 19.7 0.0 0.0026 16.1 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 KXX81156.1 - 0.00031 20.6 0.1 0.042 13.7 0.0 3.8 4 1 0 4 4 4 1 Exportin 1-like protein zf-CCHC PF00098.18 KXX81157.1 - 0.00016 21.4 0.8 0.0003 20.5 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KXX81157.1 - 0.41 10.4 5.8 0.65 9.7 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.23 KXX81158.1 - 8.8e-38 129.7 0.3 1.3e-37 129.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KXX81159.1 - 2.7e-53 180.3 0.1 3.1e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 KXX81159.1 - 0.012 15.9 0.1 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 ML domain GATase_7 PF13537.1 KXX81160.1 - 0.0049 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain PBP1_TM PF14812.1 KXX81160.1 - 0.017 15.4 0.9 0.052 13.8 0.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KilA-N PF04383.8 KXX81160.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 KilA-N domain GATase_6 PF13522.1 KXX81160.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF4611 PF15387.1 KXX81160.1 - 0.76 9.9 7.3 2 8.6 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NAD_binding_2 PF03446.10 KXX81161.1 - 5.2e-37 127.1 0.0 7.6e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KXX81161.1 - 6.3e-33 113.4 0.1 1.5e-32 112.2 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KXX81161.1 - 3.5e-07 29.2 0.0 5.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KXX81161.1 - 1.6e-06 28.4 0.1 5.9e-06 26.6 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KXX81161.1 - 1.9e-05 25.1 0.0 4.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KXX81161.1 - 0.00057 20.1 0.0 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KXX81161.1 - 0.00091 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 KXX81161.1 - 0.016 14.8 0.0 0.053 13.1 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KXX81161.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RTA1 PF04479.8 KXX81162.1 - 3.8e-34 118.1 1.4 5.2e-34 117.6 1.0 1.2 1 0 0 1 1 1 1 RTA1 like protein ALG3 PF05208.8 KXX81163.1 - 3.4e-146 487.2 15.4 3.9e-146 487.0 10.7 1.0 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.19 KXX81164.1 - 1.8e-28 99.4 1.6 2.7e-28 98.9 1.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX81164.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX81164.1 - 0.00031 20.6 0.1 0.00099 19.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX81164.1 - 0.0029 16.7 0.9 0.011 14.8 0.0 2.3 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 KXX81164.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KXX81164.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX81164.1 - 0.0063 15.0 0.1 0.0088 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KXX81164.1 - 0.061 12.1 0.2 0.09 11.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 KXX81164.1 - 0.075 12.4 0.2 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IncA PF04156.9 KXX81165.1 - 0.0032 17.0 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 IncA protein KxDL PF10241.4 KXX81165.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein NPV_P10 PF05531.7 KXX81165.1 - 0.1 12.8 2.2 2.9 8.2 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Thioredoxin PF00085.15 KXX81166.1 - 6.4e-28 96.4 0.2 7.3e-28 96.2 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX81166.1 - 5.3e-09 36.2 0.2 3.3e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX81166.1 - 5.8e-07 29.5 0.0 0.00053 20.0 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 KXX81166.1 - 3.2e-05 23.4 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KXX81166.1 - 0.00013 21.5 0.2 0.027 14.0 0.1 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KXX81166.1 - 0.0017 18.0 0.1 0.04 13.6 0.1 2.0 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KXX81166.1 - 0.0075 16.2 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 KXX81166.1 - 0.072 12.8 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 KXX81166.1 - 0.18 11.8 0.5 0.45 10.5 0.3 1.7 1 1 0 1 1 1 0 Glutaredoxin WSC PF01822.14 KXX81167.1 - 2e-20 72.5 8.5 3.5e-20 71.7 5.9 1.4 1 0 0 1 1 1 1 WSC domain Gamma-thionin PF00304.15 KXX81167.1 - 4.2 7.4 7.1 0.22 11.5 0.9 1.9 2 0 0 2 2 2 0 Gamma-thionin family Transferase PF02458.10 KXX81168.1 - 2.2e-20 72.5 0.0 2.4e-19 69.1 0.0 1.9 1 1 0 1 1 1 1 Transferase family COesterase PF00135.23 KXX81169.1 - 3.2e-96 323.1 0.0 3e-88 296.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX81169.1 - 3.2e-10 39.9 0.0 5.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX81169.1 - 0.0031 17.2 0.1 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Na_Ca_ex PF01699.19 KXX81170.1 - 1.6e-24 86.1 19.7 3.4e-15 55.8 2.5 3.1 2 2 1 3 3 3 2 Sodium/calcium exchanger protein DUF3169 PF11368.3 KXX81170.1 - 0.01 15.0 2.0 0.012 14.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pectate_lyase PF03211.8 KXX81171.1 - 2.6e-81 272.1 8.4 3.7e-81 271.6 5.9 1.1 1 0 0 1 1 1 1 Pectate lyase APH PF01636.18 KXX81172.1 - 1.3e-28 100.3 0.1 2.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KXX81172.1 - 0.018 13.6 0.0 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KXX81172.1 - 0.035 13.2 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KXX81172.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Armet PF10208.4 KXX81172.1 - 0.19 11.4 0.6 0.38 10.3 0.4 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Ifi-6-16 PF06140.8 KXX81173.1 - 0.00031 20.4 11.5 0.00054 19.7 8.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family FAD_binding_3 PF01494.14 KXX81174.1 - 1.6e-20 73.5 0.0 3.7e-20 72.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX81174.1 - 7.4e-09 34.9 1.4 0.0025 16.7 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase SE PF08491.5 KXX81174.1 - 0.0028 16.5 0.0 0.014 14.2 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KXX81174.1 - 0.005 16.8 0.3 0.005 16.8 0.2 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX81174.1 - 0.03 14.2 0.6 0.053 13.3 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX81174.1 - 0.039 12.5 3.6 0.86 8.1 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 KXX81174.1 - 0.053 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AAA PF00004.24 KXX81176.1 - 7.8e-21 74.6 0.5 2.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX81176.1 - 0.00018 21.5 1.8 0.0011 19.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KXX81176.1 - 0.00043 20.4 2.6 0.0097 16.0 0.2 3.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KXX81176.1 - 0.00063 19.6 0.9 0.03 14.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KXX81176.1 - 0.00078 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX81176.1 - 0.002 18.9 0.9 0.19 12.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX81176.1 - 0.0022 17.7 0.1 0.0061 16.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KXX81176.1 - 0.0031 17.7 0.9 0.063 13.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 KXX81176.1 - 0.0079 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KXX81176.1 - 0.014 15.3 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KXX81176.1 - 0.017 14.2 0.9 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KXX81176.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KXX81176.1 - 0.022 14.1 0.1 0.057 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KXX81176.1 - 0.029 14.2 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 KXX81176.1 - 0.064 12.7 0.2 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 KXX81176.1 - 0.075 12.5 0.7 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KXX81176.1 - 0.084 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KXX81176.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Carbpep_Y_N PF05388.6 KXX81178.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide NAD_binding_4 PF07993.7 KXX81179.1 - 9.4e-23 80.4 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KXX81179.1 - 4.6e-05 22.9 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX81179.1 - 0.0021 16.8 0.0 0.0046 15.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TRAM_LAG1_CLN8 PF03798.11 KXX81180.1 - 9.8e-34 116.6 17.9 2e-33 115.6 12.4 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KXX81180.1 - 1.1e-23 82.4 0.9 2.4e-23 81.3 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein HORMA PF02301.13 KXX81181.1 - 2.4e-18 66.3 0.0 6.1e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 HORMA domain RhoGEF PF00621.15 KXX81182.1 - 1.4e-27 96.7 1.4 7.7e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 RhoGEF domain EST1_DNA_bind PF10373.4 KXX81182.1 - 0.0085 15.3 0.1 0.0085 15.3 0.1 2.7 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain DUF3507 PF12015.3 KXX81182.1 - 0.018 14.5 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF3584 PF12128.3 KXX81182.1 - 3.2 4.9 17.6 0.039 11.2 7.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Crystall_3 PF08964.5 KXX81183.1 - 0.0095 15.6 0.3 0.28 10.9 0.1 2.1 1 1 1 2 2 2 2 Beta/Gamma crystallin Crystall PF00030.14 KXX81183.1 - 0.046 13.6 1.5 0.1 12.4 1.1 1.6 1 1 0 1 1 1 0 Beta/Gamma crystallin Pkinase PF00069.20 KXX81184.1 - 2.2e-06 27.0 0.1 3.1e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81184.1 - 0.0079 15.2 0.0 0.029 13.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase SpoIIID PF12116.3 KXX81184.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Pox_ser-thr_kin PF05445.6 KXX81184.1 - 0.34 9.6 0.1 0.5 9.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FAD_binding_4 PF01565.18 KXX81185.1 - 1e-17 63.8 2.1 1.6e-17 63.2 1.0 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX81185.1 - 2.9e-10 39.8 0.2 8.3e-10 38.4 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like Alpha_kinase PF02816.13 KXX81186.1 - 0.00051 19.7 0.1 0.0023 17.6 0.1 1.9 2 0 0 2 2 2 1 Alpha-kinase family VWA_2 PF13519.1 KXX81186.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain PapC_C PF13953.1 KXX81186.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 PapC C-terminal domain Ras PF00071.17 KXX81187.1 - 7.9e-49 165.1 0.0 1.2e-37 128.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KXX81187.1 - 2.9e-16 60.0 0.0 1.8e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX81187.1 - 2.4e-08 33.4 0.0 3.7e-07 29.5 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX81187.1 - 4.9e-05 22.8 0.0 0.00018 21.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX81187.1 - 0.00052 19.9 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KXX81187.1 - 0.0008 18.6 0.0 0.0058 15.8 0.0 2.1 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KXX81187.1 - 0.014 15.5 0.0 0.051 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KXX81187.1 - 0.14 12.1 0.2 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KXX81187.1 - 0.15 11.5 0.0 0.82 9.1 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Herpes_BLLF1 PF05109.8 KXX81187.1 - 0.58 8.0 8.7 0.76 7.6 6.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PMT PF02366.13 KXX81188.1 - 7.1e-78 261.3 17.4 7.1e-78 261.3 12.1 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KXX81188.1 - 9.7e-38 129.6 0.2 1.3e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 KXX81188.1 - 0.032 13.7 4.9 0.031 13.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) WW PF00397.21 KXX81189.1 - 2.4e-08 33.6 6.0 4.8e-08 32.7 4.1 1.5 1 0 0 1 1 1 1 WW domain CtaG_Cox11 PF04442.9 KXX81190.1 - 3e-57 192.6 0.0 4.8e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Amino_oxidase PF01593.19 KXX81191.1 - 7.5e-15 54.9 0.2 5.4e-13 48.8 0.2 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX81191.1 - 2.6e-13 49.7 0.0 6.8e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX81191.1 - 2.2e-07 31.1 0.1 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX81191.1 - 1.2e-06 28.4 0.1 0.04 13.7 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KXX81191.1 - 1.8e-06 27.1 1.7 0.00012 21.1 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX81191.1 - 0.00057 20.2 0.1 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX81191.1 - 0.0011 17.5 0.0 0.99 7.7 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein DUF4462 PF14692.1 KXX81191.1 - 0.0093 15.1 0.2 0.023 13.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4462) Pyr_redox_2 PF07992.9 KXX81191.1 - 0.016 15.1 0.0 0.085 12.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KXX81191.1 - 0.087 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KXX81191.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain L51_S25_CI-B8 PF05047.11 KXX81192.1 - 1.6e-19 69.3 0.0 2.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lambda_tail_I PF06805.7 KXX81192.1 - 0.0032 17.2 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Bacteriophage lambda tail assembly protein I MMR_HSR1 PF01926.18 KXX81193.1 - 5.3e-05 23.1 0.0 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Cys_Met_Meta_PP PF01053.15 KXX81194.1 - 1.1e-151 504.5 0.0 1.3e-151 504.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KXX81194.1 - 3.8e-13 49.2 0.4 8.5e-13 48.0 0.2 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KXX81194.1 - 4.5e-10 39.0 0.1 7.4e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KXX81194.1 - 9.8e-09 34.4 0.2 1.7e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KXX81194.1 - 3e-07 29.8 0.0 5.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KXX81194.1 - 3.3e-05 22.3 0.1 4.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KXX81194.1 - 0.0036 16.0 0.0 0.0058 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SelA PF03841.8 KXX81194.1 - 0.016 13.9 0.1 0.058 12.1 0.1 1.9 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Ribosomal_60s PF00428.14 KXX81194.1 - 0.47 10.8 6.9 3.6 8.0 1.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2012 PF09430.5 KXX81195.1 - 7.3e-11 41.9 0.0 1.5e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) PUF PF00806.14 KXX81196.1 - 1.9e-37 124.6 0.7 2.9e-06 26.4 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 KXX81196.1 - 0.1 13.2 0.0 2.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Regulator of ribonuclease activity B MRP-S33 PF08293.6 KXX81197.1 - 2.2e-28 98.0 0.1 2.6e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MutL_C PF08676.6 KXX81197.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 MutL C terminal dimerisation domain Aldo_ket_red PF00248.16 KXX81198.1 - 6.4e-48 162.9 0.0 8.9e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KXX81199.1 - 3.9e-120 401.4 0.0 4.8e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.17 KXX81201.1 - 1.7e-75 254.4 0.0 7.3e-74 249.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KXX81201.1 - 2.3e-19 68.9 0.2 7.7e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KXX81201.1 - 4.6e-19 67.3 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KXX81201.1 - 3.7e-14 52.6 0.0 1.1e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KXX81201.1 - 7.5e-09 35.2 0.4 7.5e-09 35.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KXX81201.1 - 0.0012 18.5 0.0 0.064 13.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 KXX81201.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Ribonuclease_3 PF00636.21 KXX81202.1 - 8e-16 58.5 0.2 2.9e-15 56.6 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KXX81202.1 - 4.3e-14 52.5 0.0 7.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KXX81202.1 - 0.09 13.3 0.3 0.24 11.9 0.2 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding motif ACBP PF00887.14 KXX81203.1 - 1.9e-31 107.5 0.0 3.1e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.4 KXX81203.1 - 0.53 9.1 1.9 2.1 7.1 0.5 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3712 PF12505.3 KXX81205.1 - 2.3e-08 34.1 0.5 1.4e-07 31.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KXX81205.1 - 3.9e-06 27.1 1.1 0.037 14.4 0.1 4.4 4 0 0 4 4 4 2 Late embryogenesis abundant protein INCA1 PF15142.1 KXX81206.1 - 0.1 12.3 1.2 1.1 9.0 0.1 2.1 1 1 1 2 2 2 0 INCA1 Autoind_synth PF00765.12 KXX81206.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Autoinducer synthetase GYF PF02213.11 KXX81208.1 - 1.8e-11 43.4 0.2 3.7e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 GYF domain HTH_Tnp_Mu_1 PF02316.11 KXX81208.1 - 0.0037 16.9 0.4 0.0081 15.8 0.3 1.5 1 0 0 1 1 1 1 Mu DNA-binding domain Dysbindin PF04440.11 KXX81208.1 - 0.043 13.5 6.9 0.17 11.6 4.8 2.0 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Gluconate_2-dh3 PF13618.1 KXX81208.1 - 0.84 9.7 7.4 6.1 7.0 5.1 2.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 TIP49 PF06068.8 KXX81209.1 - 8.9e-175 581.1 3.4 1e-174 580.9 2.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KXX81209.1 - 2.2e-08 34.3 0.3 2e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX81209.1 - 5.2e-08 32.2 2.1 1.9e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KXX81209.1 - 7.2e-07 28.3 0.6 1.2e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KXX81209.1 - 0.00012 22.1 0.0 0.001 19.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX81209.1 - 0.00072 19.7 0.0 0.85 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KXX81209.1 - 0.0016 18.3 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX81209.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KXX81209.1 - 0.0029 16.7 1.0 0.04 13.0 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KXX81209.1 - 0.0071 15.8 0.1 1.5 8.2 0.1 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 KXX81209.1 - 0.015 15.0 0.2 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX81209.1 - 0.02 14.6 0.6 0.068 12.9 0.3 2.0 1 1 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KXX81209.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KXX81209.1 - 0.05 13.1 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KXX81209.1 - 0.071 11.7 0.1 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KXX81209.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CDC45 PF02724.9 KXX81210.1 - 0.16 9.9 5.9 0.17 9.8 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.4 KXX81210.1 - 0.22 9.6 6.6 0.25 9.4 4.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator IER PF05760.7 KXX81210.1 - 0.28 11.0 4.6 0.31 10.9 3.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Pol_alpha_B_N PF08418.5 KXX81210.1 - 0.35 10.3 8.1 0.14 11.6 4.0 1.4 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF1510 PF07423.6 KXX81210.1 - 1.6 8.0 14.6 2 7.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3246 PF11596.3 KXX81211.1 - 0.0066 15.7 1.6 0.0099 15.1 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) DUF2399 PF09664.5 KXX81211.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) DUF1764 PF08576.5 KXX81211.1 - 0.16 12.7 3.8 0.87 10.4 2.6 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TFIIF_alpha PF05793.7 KXX81211.1 - 0.95 7.7 10.8 1.3 7.2 7.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TAF4 PF05236.9 KXX81211.1 - 7.4 5.7 7.0 10 5.3 4.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ORC6 PF05460.8 KXX81211.1 - 8.1 5.4 13.6 3.4e+02 0.0 9.4 2.1 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-box-like PF12937.2 KXX81212.1 - 4.3e-05 23.1 0.4 9.8e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like UFD1 PF03152.9 KXX81213.1 - 3.3e-66 221.7 0.0 4.1e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Choline_transpo PF04515.7 KXX81214.1 - 1.4e-11 43.7 28.7 5.1e-10 38.6 13.9 2.7 3 0 0 3 3 3 2 Plasma-membrane choline transporter DUF726 PF05277.7 KXX81215.1 - 4.8e-108 361.1 1.7 4.8e-108 361.1 1.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 KXX81216.1 - 0.0027 17.4 0.1 0.0065 16.2 0.0 1.6 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DENN PF02141.16 KXX81217.1 - 4.3e-57 192.8 0.0 7.1e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KXX81217.1 - 1e-18 67.1 0.1 1.8e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KXX81217.1 - 9.8e-17 60.6 0.0 2.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 uDENN domain Collagen PF01391.13 KXX81217.1 - 0.0098 15.4 6.4 0.018 14.5 4.4 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) C1_1 PF00130.17 KXX81217.1 - 0.018 14.7 7.4 0.035 13.8 5.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.5 KXX81217.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Stabilization of polarity axis GAT PF03127.9 KXX81217.1 - 0.21 11.5 0.3 0.95 9.4 0.0 2.0 2 0 0 2 2 2 0 GAT domain PHD PF00628.24 KXX81217.1 - 0.49 10.1 7.2 1.2 8.9 5.0 1.7 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 KXX81217.1 - 1.6 8.8 6.8 3.2 7.8 4.7 1.5 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 KXX81217.1 - 3.6 7.7 7.8 7.4 6.7 5.4 1.5 1 0 0 1 1 1 0 C1 domain PPI_Ypi1 PF07491.6 KXX81218.1 - 1.1e-22 79.4 6.9 7.1e-22 76.8 4.7 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF3597 PF12200.3 KXX81218.1 - 0.14 12.5 1.3 0.27 11.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Cwf_Cwc_15 PF04889.7 KXX81218.1 - 0.51 10.0 4.9 0.11 12.2 0.9 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 KXX81218.1 - 4.2 5.2 7.3 5.5 4.9 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 KXX81218.1 - 6.4 5.6 5.7 6.6 5.6 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter KH_1 PF00013.24 KXX81219.1 - 9.1e-13 47.6 0.0 5.9e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KXX81219.1 - 7.5e-08 31.8 1.6 1.9e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 KH domain DUF974 PF06159.8 KXX81220.1 - 1.4e-83 280.1 0.0 1.7e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Gryzun PF07919.7 KXX81220.1 - 0.0016 16.8 0.0 0.0026 16.1 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi OTCace PF00185.19 KXX81221.1 - 5.2e-42 143.4 0.0 7.7e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KXX81221.1 - 5.5e-40 136.2 0.1 8.2e-40 135.7 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain HNF-1B_C PF04812.8 KXX81221.1 - 0.0085 15.3 0.2 0.0085 15.3 0.1 1.5 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus ALS_ss_C PF10369.4 KXX81222.1 - 1.2e-19 69.7 0.0 5.2e-18 64.5 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KXX81222.1 - 4.2e-13 48.4 0.1 8.3e-13 47.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KXX81222.1 - 1.3e-09 37.6 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 ACT domain POM121 PF15229.1 KXX81222.1 - 1.8 7.9 6.1 2.9 7.2 4.2 1.2 1 0 0 1 1 1 0 POM121 family SNAP PF14938.1 KXX81223.1 - 1.7e-108 362.1 21.2 1.9e-108 361.9 14.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KXX81223.1 - 4.3e-06 26.5 13.2 0.00097 19.0 1.3 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX81223.1 - 6e-05 22.6 12.3 1.3 9.0 1.6 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81223.1 - 0.096 13.3 12.1 21 6.0 0.0 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX81223.1 - 0.14 12.0 5.9 16 5.5 0.1 4.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KXX81223.1 - 0.43 10.2 18.8 0.25 11.0 2.8 3.4 1 1 2 3 3 3 0 TPR repeat TPR_6 PF13174.1 KXX81223.1 - 4.8 7.8 16.8 60 4.4 0.0 6.1 4 2 2 6 6 6 0 Tetratricopeptide repeat NUC173 PF08161.7 KXX81224.1 - 2.8e-79 265.0 0.0 3.4e-76 255.0 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 KXX81224.1 - 0.00063 19.6 0.2 1.6 9.0 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KXX81224.1 - 0.019 15.2 8.2 0.097 12.9 0.7 4.0 4 0 0 4 4 4 0 HEAT repeats MARVEL PF01284.18 KXX81225.1 - 7.5e-19 67.9 18.5 9.1e-19 67.7 12.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.23 KXX81226.1 - 3.5e-80 269.4 0.0 4.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NPP1 PF05630.6 KXX81227.1 - 9.5e-66 221.4 1.3 1.1e-65 221.2 0.9 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Chorion_2 PF03964.10 KXX81230.1 - 4.3 7.9 13.0 1.7 9.2 0.5 3.3 3 0 0 3 3 3 0 Chorion family 2 Cpn60_TCP1 PF00118.19 KXX81232.1 - 1.5e-119 399.8 9.9 1.7e-119 399.6 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Baculo_PEP_C PF04513.7 KXX81233.1 - 6.2e-06 26.0 20.6 0.039 13.7 3.2 5.4 2 1 3 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 KXX81233.1 - 0.00011 20.1 34.2 0.00011 20.1 23.7 2.9 2 1 1 3 3 3 2 Myosin tail Reo_sigmaC PF04582.7 KXX81233.1 - 0.00025 20.3 21.9 0.034 13.3 0.2 5.1 1 1 5 6 6 6 4 Reovirus sigma C capsid protein Transcrip_act PF04949.8 KXX81233.1 - 0.01 15.4 33.7 0.034 13.7 0.1 5.4 3 1 3 6 6 6 0 Transcriptional activator Filament PF00038.16 KXX81233.1 - 0.012 15.0 49.0 0.57 9.5 4.4 4.7 1 1 2 4 4 4 0 Intermediate filament protein Bacillus_HBL PF05791.6 KXX81233.1 - 0.017 14.4 34.8 0.038 13.3 1.8 5.2 2 2 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 KXX81233.1 - 0.018 14.7 32.3 0.27 11.0 0.2 6.1 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 KXX81233.1 - 0.019 14.9 17.7 1.2 9.1 0.0 7.2 5 2 3 8 8 8 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 KXX81233.1 - 0.09 12.9 26.0 0.27 11.3 0.0 6.4 4 3 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KXX81233.1 - 0.18 11.6 23.5 1.3 8.9 0.0 6.6 4 3 3 7 7 7 0 Bacterial protein of unknown function (DUF948) DUF3618 PF12277.3 KXX81233.1 - 0.44 10.6 6.7 0.67 10.0 0.4 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3618) CENP-F_leu_zip PF10473.4 KXX81233.1 - 0.98 9.2 51.7 0.98 9.2 0.6 5.9 2 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KXX81233.1 - 1 7.7 35.3 0.14 10.6 3.1 3.0 1 1 0 2 2 2 0 AAA domain Prominin PF05478.6 KXX81233.1 - 3.1 5.2 29.1 2.2 5.7 3.8 3.1 1 1 2 3 3 3 0 Prominin FlaC_arch PF05377.6 KXX81233.1 - 6 6.8 27.9 14 5.6 0.1 8.3 5 3 2 7 7 7 0 Flagella accessory protein C (FlaC) Blt1 PF12754.2 KXX81234.1 - 3.3e-32 112.3 0.0 2.9e-30 105.9 0.0 2.0 1 1 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 KXX81234.1 - 0.00024 20.4 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family MYT1 PF08474.6 KXX81234.1 - 0.061 12.7 0.8 0.091 12.2 0.5 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 Cofilin_ADF PF00241.15 KXX81235.1 - 2.6e-37 127.5 0.5 3e-37 127.3 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XRCC4 PF06632.7 KXX81236.1 - 3.5e-09 35.9 1.5 5e-09 35.4 1.0 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.3 KXX81236.1 - 0.0029 17.4 6.0 0.0046 16.8 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) Mnd1 PF03962.10 KXX81236.1 - 0.048 13.3 4.4 0.075 12.6 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family SlyX PF04102.7 KXX81236.1 - 0.23 11.8 1.6 0.85 10.0 0.8 2.3 1 1 0 1 1 1 0 SlyX DUF3573 PF12097.3 KXX81236.1 - 0.23 10.0 0.2 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PALP PF00291.20 KXX81238.1 - 5.8e-62 209.6 0.2 7.3e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KXX81238.1 - 7.9e-08 31.9 0.0 1.5e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain AAA_19 PF13245.1 KXX81238.1 - 0.34 10.6 3.1 0.31 10.8 0.6 2.0 2 0 0 2 2 2 0 Part of AAA domain SRPRB PF09439.5 KXX81239.1 - 2.7e-22 78.8 0.0 5.4e-15 55.0 0.0 3.2 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KXX81239.1 - 0.00074 19.5 0.8 0.002 18.1 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KXX81239.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KXX81239.1 - 0.0049 16.1 0.0 0.45 9.7 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family Zeta_toxin PF06414.7 KXX81239.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KXX81239.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 KXX81239.1 - 0.023 14.1 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KXX81239.1 - 0.025 14.0 0.1 0.073 12.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KXX81239.1 - 0.043 13.0 0.2 0.15 11.2 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX81239.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KXX81239.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KXX81239.1 - 0.096 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Vac7 PF12751.2 KXX81239.1 - 0.098 11.4 0.1 5.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 AAA_5 PF07728.9 KXX81239.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 KXX81239.1 - 0.21 10.6 0.0 1.3 8.1 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Zn_clus PF00172.13 KXX81240.1 - 5.7e-09 35.7 10.1 1.1e-08 34.7 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX81240.1 - 7.3e-09 34.8 0.0 1.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KXX81241.1 - 9.1e-20 70.6 15.2 1.2e-19 70.2 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KXX81241.1 - 9.9e-06 24.1 0.5 2.1e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 KXX81241.1 - 0.02 14.6 0.4 0.14 11.9 0.4 2.4 2 0 0 2 2 2 0 MFS_1 like family PIP5K PF01504.13 KXX81245.1 - 6.7e-31 107.3 0.0 8.9e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase UDPG_MGDP_dh_N PF03721.9 KXX81249.1 - 8.7e-50 168.6 0.1 1.5e-34 118.9 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KXX81249.1 - 5.4e-24 84.2 0.0 1.4e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KXX81249.1 - 8.6e-23 80.5 0.0 6.5e-17 61.6 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain adh_short PF00106.20 KXX81250.1 - 5.3e-11 42.7 0.2 1.1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX81250.1 - 0.00034 20.3 0.1 0.00075 19.2 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX81250.1 - 0.00054 19.7 0.1 0.0023 17.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KXX81250.1 - 0.001 18.8 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ank PF00023.25 KXX81252.1 - 1.3e-34 116.3 1.7 2.5e-08 33.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 KXX81252.1 - 2.6e-34 118.1 7.6 2.6e-34 118.1 5.3 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KXX81252.1 - 6e-33 113.0 0.0 7.4e-17 61.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX81252.1 - 1.4e-25 88.6 1.0 1.7e-07 31.2 0.0 5.4 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81252.1 - 9.3e-24 81.1 0.4 7.9e-08 31.8 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KXX81252.1 - 2e-22 79.1 3.5 2.5e-07 31.0 0.1 4.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) lci PF12197.3 KXX81252.1 - 0.13 11.9 0.5 0.29 10.7 0.4 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein DLH PF01738.13 KXX81253.1 - 2.6e-29 102.0 0.0 3.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX81253.1 - 8.8e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Gly_transf_sug PF04488.10 KXX81254.1 - 1.4e-09 38.2 0.1 2.9e-09 37.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif zf-CCCH PF00642.19 KXX81256.1 - 0.00059 19.4 4.7 0.00059 19.4 3.3 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KTSC PF13619.1 KXX81257.1 - 0.048 13.3 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 KTSC domain Metal_resist PF13801.1 KXX81257.1 - 0.13 12.2 1.5 0.22 11.5 1.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance zf-C2H2 PF00096.21 KXX81258.1 - 0.0055 16.9 5.6 0.026 14.8 1.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KXX81258.1 - 0.0059 16.7 2.0 0.017 15.2 1.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX81258.1 - 0.0074 16.4 3.6 0.034 14.3 1.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KXX81258.1 - 0.023 15.0 2.1 0.023 15.0 1.5 3.2 2 1 1 3 3 3 0 C2H2-type zinc finger Peroxidase_2 PF01328.12 KXX81259.1 - 2.4e-16 59.3 0.0 2.9e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 T2SK PF03934.8 KXX81259.1 - 0.054 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K An_peroxidase PF03098.10 KXX81260.1 - 3.3e-118 395.3 0.0 4.1e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Glyco_hydro_3 PF00933.16 KXX81261.1 - 4.7e-92 308.1 0.0 6.9e-92 307.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX81261.1 - 4.4e-56 189.9 0.7 1.6e-55 188.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX81261.1 - 5.6e-15 55.0 0.4 1.8e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain LSM PF01423.17 KXX81262.1 - 9.8e-17 60.2 0.1 1.4e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain TrbC PF04956.8 KXX81263.1 - 1.7 8.7 5.5 0.95 9.5 1.9 1.8 2 0 0 2 2 2 0 TrbC/VIRB2 family Glyco_hydro_61 PF03443.9 KXX81265.1 - 5.2e-59 199.6 0.0 9.5e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KXX81265.1 - 1.6e-09 37.2 13.9 1.6e-09 37.2 9.6 3.9 3 1 0 3 3 3 1 Fungal cellulose binding domain Flavokinase PF01687.12 KXX81266.1 - 1.2e-08 34.9 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase ERG4_ERG24 PF01222.12 KXX81267.1 - 4.9e-176 585.4 1.2 5.5e-176 585.3 0.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KXX81267.1 - 0.00055 19.3 0.1 0.0014 17.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 KXX81268.1 - 6.7e-12 44.9 0.1 1.2e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KXX81268.1 - 7.4e-07 29.0 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KXX81268.1 - 5.9e-06 25.7 10.9 9.6e-05 21.7 7.5 2.5 1 1 0 1 1 1 1 Autophagy-related protein 27 PPP4R2 PF09184.6 KXX81268.1 - 0.022 14.3 9.1 0.16 11.5 7.5 1.5 2 0 0 2 2 2 0 PPP4R2 FemAB PF02388.11 KXX81268.1 - 0.048 12.3 0.3 0.068 11.8 0.2 1.1 1 0 0 1 1 1 0 FemAB family Daxx PF03344.10 KXX81268.1 - 0.081 11.4 13.1 0.11 10.9 9.1 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 KXX81268.1 - 1.3 8.5 18.5 2.3 7.6 12.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 KXX81268.1 - 1.3 8.1 18.0 1.8 7.7 12.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KXX81268.1 - 2.5 6.0 15.8 4 5.3 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.10 KXX81268.1 - 7.8 4.4 8.6 0.44 8.6 2.5 1.4 2 0 0 2 2 2 0 Atrophin-1 family TRAP_alpha PF03896.11 KXX81268.1 - 8.4 5.2 10.2 14 4.5 7.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GFA PF04828.9 KXX81269.1 - 2.8e-05 23.9 1.0 2.8e-05 23.9 0.7 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2510 PF10708.4 KXX81269.1 - 0.076 12.4 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Glyco_hydro_61 PF03443.9 KXX81270.1 - 3.9e-56 190.2 0.0 4.8e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.6 KXX81271.1 - 3.7e-20 72.5 0.0 5.7e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NicO PF03824.11 KXX81272.1 - 7e-66 222.4 7.3 1.1e-65 221.8 5.1 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein PepSY_TM_2 PF13703.1 KXX81272.1 - 2.3 8.4 13.4 0.99 9.6 0.6 4.5 4 1 0 4 4 4 0 PepSY-associated TM helix TIP39 PF14980.1 KXX81274.1 - 0.02 14.4 0.4 0.047 13.3 0.2 1.6 1 0 0 1 1 1 0 TIP39 peptide Fungal_trans PF04082.13 KXX81275.1 - 5.7e-22 77.8 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KXX81276.1 - 5e-16 58.5 0.1 8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_10 PF00331.15 KXX81276.1 - 0.0068 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 OmdA PF13376.1 KXX81277.1 - 7.8e-24 83.1 0.8 7.8e-24 83.1 0.5 2.6 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated Peptidase_C12 PF01088.16 KXX81278.1 - 1.9e-43 148.1 0.0 7.9e-27 93.8 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 PCMT PF01135.14 KXX81280.1 - 5.6e-54 182.8 0.0 6.5e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KXX81280.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81280.1 - 2.1e-05 24.1 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX81280.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81280.1 - 0.00037 20.2 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81280.1 - 0.00052 20.0 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KXX81280.1 - 0.028 15.2 0.2 0.1 13.4 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81280.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KXX81280.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KXX81280.1 - 0.15 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KXX81280.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) OTT_1508_deam PF14441.1 KXX81281.1 - 3.7e-05 23.5 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.17 KXX81281.1 - 0.00045 19.8 0.1 0.00084 18.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SCP1201-deam PF14428.1 KXX81281.1 - 0.0031 17.2 0.1 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 SCP1.201-like deaminase DUF1923 PF09083.5 KXX81281.1 - 0.019 14.4 2.0 0.21 11.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1923) YwqJ-deaminase PF14431.1 KXX81281.1 - 0.2 11.4 1.0 6.9 6.5 0.7 2.4 1 1 0 1 1 1 0 YwqJ-like deaminase Spc7 PF08317.6 KXX81282.1 - 0.51 8.9 30.0 1.6 7.2 13.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2370 PF10176.4 KXX81284.1 - 3.2e-84 281.9 0.0 5.4e-84 281.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 KXX81284.1 - 0.039 14.1 0.1 0.21 11.7 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Mito_carr PF00153.22 KXX81286.1 - 1.3e-54 181.9 6.9 1.2e-22 79.4 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein PTR2 PF00854.16 KXX81287.1 - 1e-09 37.6 2.0 7.1e-06 25.0 0.2 2.1 2 0 0 2 2 2 2 POT family DUF4231 PF14015.1 KXX81288.1 - 0.48 10.4 0.1 0.48 10.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) IDO PF01231.13 KXX81291.1 - 6.7e-09 34.6 0.0 3.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase HET PF06985.6 KXX81292.1 - 3.4e-20 72.6 0.0 6.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.23 KXX81293.1 - 2.1e-59 201.6 0.0 3.4e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX81293.1 - 2.6e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX81293.1 - 0.0038 16.4 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Zn_clus PF00172.13 KXX81294.1 - 2.1e-07 30.7 13.7 4.7e-07 29.6 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX81294.1 - 7e-06 24.8 1.2 1e-05 24.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATX_III PF08098.6 KXX81295.1 - 0.033 13.9 0.5 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family RNA_helicase PF00910.17 KXX81295.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Peroxidase_2 PF01328.12 KXX81297.1 - 9.4e-38 129.6 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 E1-E2_ATPase PF00122.15 KXX81298.1 - 6.3e-65 218.4 1.7 6.3e-65 218.4 1.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX81298.1 - 4.3e-32 111.1 6.5 4.3e-32 111.1 4.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX81298.1 - 1.2e-29 104.2 0.0 1.1e-28 101.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX81298.1 - 3.3e-18 65.4 0.0 7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KXX81298.1 - 1.5e-16 59.6 0.1 7e-16 57.4 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KXX81298.1 - 2.4e-14 53.9 0.0 6.8e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX81298.1 - 0.0012 18.4 0.2 0.0062 16.1 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 KXX81298.1 - 0.026 14.0 0.3 0.069 12.7 0.2 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B Piwi PF02171.12 KXX81299.1 - 1.7e-77 260.4 0.0 2.7e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KXX81299.1 - 1.7e-14 52.8 0.1 3.7e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KXX81299.1 - 7.4e-12 44.7 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain NmrA PF05368.8 KXX81300.1 - 1.9e-14 53.5 0.0 2.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX81300.1 - 9.1e-12 45.3 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX81300.1 - 1.4e-07 31.2 0.0 1.9e-06 27.4 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KXX81300.1 - 0.0057 17.0 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KXX81300.1 - 0.0067 16.1 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KXX81300.1 - 0.013 15.4 0.2 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KXX81300.1 - 0.014 14.2 0.1 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KXX81300.1 - 0.015 14.2 0.1 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KXX81300.1 - 0.021 13.8 0.3 0.032 13.2 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KXX81300.1 - 0.03 13.0 0.1 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KXX81300.1 - 0.042 13.7 0.5 0.083 12.8 0.4 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GARS_N PF02844.10 KXX81300.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Fungal_trans PF04082.13 KXX81301.1 - 6.5e-10 38.3 0.0 1.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KXX81303.1 - 0.00092 19.3 0.6 0.00092 19.3 0.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX81303.1 - 0.0012 18.9 2.4 0.18 12.1 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KXX81303.1 - 0.007 16.6 0.5 0.007 16.6 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KXX81303.1 - 0.018 14.9 0.3 0.049 13.5 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 KXX81303.1 - 0.55 10.5 2.9 0.35 11.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DAO PF01266.19 KXX81304.1 - 6.7e-38 130.5 0.3 8.5e-38 130.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 KXX81304.1 - 1.1e-13 50.5 0.1 2.6e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_oxidored PF12831.2 KXX81304.1 - 6.1e-06 25.5 3.4 0.00013 21.1 2.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX81304.1 - 1.3e-05 25.1 0.2 3.1e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KXX81304.1 - 5.6e-05 22.3 0.2 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KXX81304.1 - 5.8e-05 22.1 0.2 0.0001 21.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX81304.1 - 0.00016 21.8 0.2 0.00062 19.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX81304.1 - 0.00021 21.2 0.1 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX81304.1 - 0.0018 17.4 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KXX81304.1 - 0.0039 16.1 0.1 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 KXX81304.1 - 0.0084 15.0 0.4 0.038 12.8 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KXX81304.1 - 0.012 16.0 0.4 0.035 14.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX81304.1 - 0.022 13.2 0.2 0.035 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 KXX81305.1 - 4.5e-21 75.4 7.5 6.3e-20 71.7 5.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81305.1 - 3e-10 40.2 0.0 2.1e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX81305.1 - 6.1e-09 35.7 0.4 6.1e-09 35.7 0.3 2.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX81305.1 - 0.00044 19.7 0.2 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KXX81305.1 - 0.0039 17.2 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KXX81305.1 - 0.008 14.9 0.0 0.013 14.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KXX81305.1 - 0.031 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SET PF00856.23 KXX81306.1 - 6.6e-11 42.7 0.0 9.2e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.7 KXX81306.1 - 0.019 15.3 0.1 8 6.9 0.0 2.7 2 0 0 2 2 2 0 SAF domain Cys_Met_Meta_PP PF01053.15 KXX81307.1 - 3.7e-29 101.1 0.0 5.7e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KXX81307.1 - 0.00021 20.3 0.0 0.00041 19.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_2 PF00891.13 KXX81308.1 - 1.3e-20 73.6 0.2 3.5e-20 72.2 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase Glyco_transf_20 PF00982.16 KXX81309.1 - 7.5e-150 499.5 0.0 1e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KXX81309.1 - 4.3e-74 248.3 0.0 1.1e-73 247.0 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 KXX81309.1 - 0.025 14.7 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KXX81309.1 - 0.18 11.2 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF3638 PF12340.3 KXX81310.1 - 2.7e-101 337.3 0.4 1.6e-100 334.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KXX81310.1 - 3.6e-14 51.5 0.0 8e-14 50.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) GFA PF04828.9 KXX81311.1 - 4.9e-11 42.4 1.7 4.9e-11 42.4 1.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_11 PF00457.12 KXX81312.1 - 2.8e-61 206.0 11.5 3.2e-61 205.8 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GFA PF04828.9 KXX81313.1 - 5.1e-14 51.9 0.7 8e-14 51.3 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KXX81313.1 - 0.0013 18.3 0.6 0.0013 18.3 0.4 2.4 3 0 0 3 3 3 1 Nudix N-terminal zf-DNL PF05180.7 KXX81313.1 - 4.6 7.0 7.7 0.95 9.2 0.9 2.2 2 0 0 2 2 2 0 DNL zinc finger EI24 PF07264.6 KXX81314.1 - 7.2e-05 22.3 15.0 0.0011 18.4 10.1 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.9 KXX81314.1 - 1.3 8.8 8.8 2 8.2 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF805) ABC2_membrane_4 PF12730.2 KXX81314.1 - 2 7.4 13.3 0.21 10.7 4.7 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Fungal_trans PF04082.13 KXX81315.1 - 1.3e-13 50.3 0.0 2.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase_2 PF12681.2 KXX81316.1 - 1.1e-08 35.5 0.1 1.7e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KXX81316.1 - 0.00017 21.5 0.0 0.00024 21.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PFL PF02901.10 KXX81317.1 - 0.16 10.3 0.0 0.21 9.9 0.0 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase 2-Hacid_dh_C PF02826.14 KXX81318.1 - 1.2e-40 138.5 0.0 4.9e-38 130.0 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KXX81318.1 - 0.0043 17.0 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KXX81318.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 KXX81319.1 - 0.011 15.7 0.2 0.041 13.8 0.0 2.0 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX81319.1 - 0.031 13.1 0.1 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KXX81319.1 - 0.035 13.1 0.1 0.043 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KXX81319.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 KXX81321.1 - 1.2e-24 86.6 66.1 2.7e-21 75.6 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.28 KXX81322.1 - 8.1e-10 38.1 1.1 1.1e-05 24.8 0.0 3.7 4 0 0 4 4 4 2 F-box domain F-box-like PF12937.2 KXX81322.1 - 4.8e-06 26.2 0.5 0.00029 20.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KXX81322.1 - 0.069 12.7 0.0 14 5.3 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Proteasome PF00227.21 KXX81323.1 - 3.3e-51 173.2 0.0 4.2e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX81323.1 - 3e-11 42.4 0.2 4.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 KXX81324.1 - 1.7e-45 153.5 8.6 1.9e-45 153.4 6.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Gram_pos_anchor PF00746.16 KXX81324.1 - 4.5 7.2 8.4 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Gram positive anchor Chorismate_bind PF00425.13 KXX81325.1 - 7.6e-63 212.2 0.2 6.4e-35 120.7 0.0 3.2 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KXX81325.1 - 1.1e-21 77.1 0.0 8.1e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KXX81325.1 - 2.1e-12 47.2 0.0 4.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KXX81325.1 - 5.1e-05 22.8 0.6 0.019 14.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 TRAPPC9-Trs120 PF08626.6 KXX81326.1 - 8.4e-142 473.8 0.0 9.7e-116 387.5 0.0 2.6 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Longin PF13774.1 KXX81327.1 - 9e-26 89.2 0.1 1.6e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KXX81327.1 - 1.1e-15 56.9 0.0 2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 KXX81327.1 - 0.017 14.9 0.8 0.017 14.9 0.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seadorna_VP6 PF07407.6 KXX81327.1 - 0.064 12.0 0.7 0.23 10.1 0.2 1.8 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF334 PF03904.8 KXX81327.1 - 0.082 12.2 2.1 6.9 5.9 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF334) DUF4404 PF14357.1 KXX81327.1 - 0.091 13.1 1.4 11 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) AIF-MLS PF14962.1 KXX81328.1 - 0.23 11.0 3.2 0.47 10.0 2.2 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF1168 PF06658.7 KXX81328.1 - 0.39 10.2 7.9 0.85 9.1 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CLPTM1 PF05602.7 KXX81329.1 - 3.6e-161 536.7 0.0 4.5e-161 536.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 KXX81330.1 - 1.9e-30 105.3 0.0 2.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Glt_symporter PF03616.9 KXX81330.1 - 0.043 12.3 2.6 1.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter Elong_Iki1 PF10483.4 KXX81331.1 - 1.4e-59 201.8 0.0 1.6e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ASXH PF13919.1 KXX81332.1 - 7.8e-20 71.0 0.1 1.4e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Asx homology domain Pmp3 PF01679.12 KXX81333.1 - 4.5e-15 55.0 13.8 6.1e-15 54.6 9.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 KXX81333.1 - 0.024 14.1 0.6 0.029 13.9 0.4 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC COX5A PF02284.11 KXX81335.1 - 7.6e-41 138.4 0.4 1.3e-40 137.7 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va GrpE PF01025.14 KXX81335.1 - 0.085 12.4 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 GrpE DUF488 PF04343.8 KXX81335.1 - 0.092 13.1 0.2 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF488 DHC_N1 PF08385.7 KXX81335.1 - 0.14 10.5 0.4 3.7 5.8 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 Reo_sigmaC PF04582.7 KXX81336.1 - 0.066 12.3 8.5 0.083 12.0 2.7 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KXX81336.1 - 0.28 10.9 30.5 0.57 9.9 5.5 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 KXX81336.1 - 0.46 10.2 22.9 0.11 12.2 5.8 3.2 1 1 2 3 3 3 0 Laminin Domain II ATG16 PF08614.6 KXX81336.1 - 0.86 9.4 36.3 2.6 7.8 10.7 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 KXX81336.1 - 2.4 7.9 32.2 5.6 6.7 5.6 3.8 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 KXX81336.1 - 7.1 5.9 34.6 3.1 7.1 7.1 3.0 1 1 0 1 1 1 0 Intermediate filament protein ELO PF01151.13 KXX81338.1 - 5.2e-63 212.6 19.3 6.1e-63 212.4 13.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p53-inducible11 PF14936.1 KXX81338.1 - 0.16 11.9 1.4 1.8 8.4 0.0 2.6 3 0 0 3 3 3 0 Tumour protein p53-inducible protein 11 Glycogen_syn PF05693.8 KXX81339.1 - 0 1154.1 0.0 0 1153.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KXX81339.1 - 9.3e-06 25.1 0.0 0.013 14.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KXX81339.1 - 2.1e-05 24.1 0.1 4.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KXX81339.1 - 4.9e-05 23.5 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F-box-like PF12937.2 KXX81340.1 - 3e-06 26.8 0.4 7.9e-06 25.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 KXX81341.1 - 2e-70 236.9 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81341.1 - 5.8e-35 120.6 0.0 1.7e-34 119.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX81341.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX81341.1 - 0.0092 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GDE_C PF06202.9 KXX81342.1 - 0.074 11.7 0.3 0.093 11.4 0.2 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase PBP1_TM PF14812.1 KXX81342.1 - 2.2 8.6 8.9 3.8 7.8 6.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MARVEL PF01284.18 KXX81343.1 - 8.2 6.2 12.0 29 4.4 8.4 1.9 1 1 0 1 1 1 0 Membrane-associating domain Pyr_redox_2 PF07992.9 KXX81344.1 - 8.5e-20 71.4 0.0 1.2e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX81344.1 - 1.1e-07 31.7 0.9 0.0017 18.1 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX81344.1 - 8.7e-07 29.2 0.9 0.012 15.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX81344.1 - 1.6e-06 27.2 2.4 4.1e-05 22.6 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KXX81344.1 - 2.6e-05 23.3 0.4 0.00019 20.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KXX81344.1 - 5e-05 22.3 0.7 0.0011 17.9 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KXX81344.1 - 8.7e-05 21.5 1.7 0.16 10.8 0.1 2.1 1 1 1 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 KXX81344.1 - 0.00045 18.7 0.2 0.0026 16.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KXX81344.1 - 0.0027 17.6 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX81344.1 - 0.0076 15.2 0.4 0.15 10.9 0.2 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KXX81344.1 - 0.088 11.8 0.2 0.32 9.9 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.12 KXX81344.1 - 0.094 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family CorA PF01544.13 KXX81345.1 - 9.3e-11 41.2 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HET PF06985.6 KXX81346.1 - 1.2e-21 77.2 0.0 2.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 KXX81347.1 - 6.1e-08 32.7 0.0 9.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX81347.1 - 1.2e-07 31.8 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF904 PF06005.7 KXX81347.1 - 0.023 14.9 0.1 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Marek_A PF02124.10 KXX81348.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.4 1 1 0 1 1 1 0 Marek's disease glycoprotein A 7TM_GPCR_Srsx PF10320.4 KXX81348.1 - 0.21 10.6 0.9 0.26 10.3 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx MFS_1 PF07690.11 KXX81349.1 - 2e-12 46.5 24.8 9.1e-07 27.8 3.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX81349.1 - 0.00014 20.2 1.1 0.0002 19.7 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX81349.1 - 0.0039 15.8 4.5 0.0039 15.8 3.1 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter GST_N PF02798.15 KXX81350.1 - 7.7e-11 42.0 0.0 1.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX81350.1 - 1.2e-08 34.8 0.0 2.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX81350.1 - 1.3e-08 34.7 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX81350.1 - 3.7e-08 33.4 0.0 7.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX81350.1 - 2e-07 30.7 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX81350.1 - 2.1e-07 31.3 0.1 3.3e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TfuA PF07812.7 KXX81351.1 - 8.4e-16 57.4 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 TfuA-like protein Cation_efflux PF01545.16 KXX81353.1 - 5.6e-30 104.3 3.5 6.7e-30 104.1 2.5 1.1 1 0 0 1 1 1 1 Cation efflux family Transport_MerF PF11431.3 KXX81353.1 - 1.9 8.2 5.6 0.31 10.7 0.8 2.0 2 0 0 2 2 2 0 Membrane transport protein MerF Glyco_transf_8 PF01501.15 KXX81354.1 - 7.2e-37 127.0 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KXX81354.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative RAMP4 PF06624.7 KXX81355.1 - 1.3e-06 27.8 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1777 PF08648.7 KXX81357.1 - 1.6e-22 80.1 111.7 2.2e-21 76.4 46.9 3.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) SMAP PF15477.1 KXX81358.1 - 1.1e-18 67.2 3.7 1.1e-18 67.2 2.5 5.1 3 1 0 3 3 3 1 Small acidic protein family RFX_DNA_binding PF02257.10 KXX81359.1 - 7.7e-30 102.8 0.1 1.8e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.3 KXX81360.1 - 1.1e-18 66.7 0.1 4.4e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KXX81360.1 - 5.3e-18 65.7 1.6 6.7e-18 65.3 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX81360.1 - 3.5e-15 56.0 0.1 5.4e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX81360.1 - 1.6e-05 24.6 0.1 2.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KXX81360.1 - 0.0055 16.3 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KXX81360.1 - 0.035 12.9 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KXX81360.1 - 0.041 13.4 0.1 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Peptidase_S9 PF00326.16 KXX81360.1 - 0.054 12.6 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mid1 PF12929.2 KXX81361.1 - 1.1e-131 439.4 0.2 1.3e-131 439.2 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KXX81361.1 - 0.047 14.0 2.0 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Fz domain TB2_DP1_HVA22 PF03134.14 KXX81362.1 - 2.5e-32 110.4 5.6 3.4e-32 110.0 3.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bestrophin PF01062.16 KXX81362.1 - 5.5 5.8 10.4 22 3.8 7.2 1.8 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel zf-RanBP PF00641.13 KXX81363.1 - 2e-18 65.1 13.3 6.9e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KXX81363.1 - 1e-08 34.6 0.0 1.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KXX81363.1 - 3e-08 34.1 0.0 4.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KXX81363.1 - 8.7e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KXX81363.1 - 2.9 7.7 10.6 0.67 9.8 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 KXX81365.1 - 5e-37 124.4 3.8 4e-09 36.0 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KXX81365.1 - 4.7e-31 106.5 0.3 1.2e-30 105.2 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 KXX81366.1 - 5.3e-104 346.7 0.0 8.8e-104 346.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 KXX81368.1 - 1.5e-32 112.1 0.1 3.5e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Hid1 PF12722.2 KXX81369.1 - 9.5e-264 877.3 0.0 3.2e-263 875.5 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KXX81369.1 - 2.6e-86 290.2 0.0 3.4e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein B56 PF01603.15 KXX81369.1 - 0.39 9.2 1.7 0.38 9.2 0.1 1.6 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) EHN PF06441.7 KXX81370.1 - 4.7e-18 65.1 0.0 8.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus NPCC PF08058.6 KXX81371.1 - 7.6e-32 110.1 0.1 4e-31 107.8 0.1 1.9 1 1 0 1 1 1 1 Nuclear pore complex component SspN PF08177.6 KXX81371.1 - 0.13 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein N family AMP-binding PF00501.23 KXX81372.1 - 9.1e-18 63.8 0.0 1.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme SurE PF01975.12 KXX81373.1 - 3.7e-28 98.1 0.2 5e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Fungal_trans PF04082.13 KXX81374.1 - 9.2e-10 37.8 0.7 1.6e-09 37.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81374.1 - 0.0037 17.1 10.6 0.0059 16.4 0.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2_2 PF01799.15 KXX81374.1 - 0.096 12.5 0.5 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 [2Fe-2S] binding domain Ctr PF04145.10 KXX81375.1 - 1.3e-43 148.5 1.1 1.5e-43 148.2 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.5 KXX81375.1 - 4.3 5.2 11.2 3.7 5.4 5.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.7 KXX81376.1 - 3.6e-102 341.4 0.0 4.7e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 KXX81377.1 - 1.6e-53 181.9 0.0 1.5e-38 132.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 KXX81378.1 - 5.3e-40 137.2 48.6 5.7e-37 127.2 20.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX81378.1 - 4.7e-13 48.5 16.7 1e-12 47.4 1.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pex14_N PF04695.8 KXX81378.1 - 0.058 13.4 1.6 0.16 12.0 1.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_U4 PF03419.8 KXX81378.1 - 1.7 7.6 3.8 3.5 6.6 2.6 1.5 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TTL PF03133.10 KXX81379.1 - 5e-34 117.5 0.0 1.9e-33 115.6 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KXX81379.1 - 0.0024 16.7 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 KXX81379.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus PHO4 PF01384.15 KXX81380.1 - 4.1e-115 383.8 8.7 9.1e-115 382.7 6.0 1.5 1 1 0 1 1 1 1 Phosphate transporter family MFS_1 PF07690.11 KXX81381.1 - 4.8e-38 130.7 57.8 8.5e-38 129.9 38.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX81381.1 - 4.2e-08 32.2 11.1 4.2e-08 32.2 7.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Corona_S2 PF01601.11 KXX81381.1 - 0.063 11.3 2.6 0.1 10.7 1.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein P2_Phage_GpR PF06891.6 KXX81382.1 - 0.067 12.9 1.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) SNARE_assoc PF09335.6 KXX81383.1 - 0.002 18.3 0.3 0.0023 18.1 0.2 1.1 1 0 0 1 1 1 1 SNARE associated Golgi protein Adeno_E3_CR2 PF02439.10 KXX81383.1 - 0.027 14.0 4.6 0.051 13.1 3.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SCIMP PF15050.1 KXX81383.1 - 0.048 13.5 0.1 0.055 13.3 0.1 1.1 1 0 0 1 1 1 0 SCIMP protein MtrF PF09472.5 KXX81383.1 - 0.059 12.6 0.3 0.093 11.9 0.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LRR19-TM PF15176.1 KXX81383.1 - 0.069 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MLANA PF14991.1 KXX81383.1 - 0.11 12.4 0.1 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A DUF2102 PF09875.4 KXX81383.1 - 0.11 11.9 0.6 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Fungal_trans_2 PF11951.3 KXX81384.1 - 1.1e-26 93.3 0.8 1.5e-26 92.9 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81384.1 - 3.6e-07 29.9 8.0 6.4e-07 29.1 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.15 KXX81385.1 - 1.1e-26 92.5 0.0 1.3e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX81385.1 - 2.7e-07 30.7 0.1 6.5e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX81385.1 - 2.4e-05 24.3 0.0 0.0018 18.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KXX81385.1 - 0.0009 18.9 0.1 0.044 13.4 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KXX81385.1 - 0.0029 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KXX81385.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 KXX81385.1 - 0.023 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 KXX81385.1 - 0.038 13.4 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF834 PF05754.9 KXX81386.1 - 0.26 11.1 6.8 4.9 7.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF834) Ctr PF04145.10 KXX81386.1 - 5.3 7.0 4.7 52 3.8 3.3 2.3 1 1 0 1 1 1 0 Ctr copper transporter family Reo_sigmaC PF04582.7 KXX81387.1 - 2.5e-09 36.7 36.4 0.0013 17.9 0.4 5.3 1 1 2 5 5 5 3 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KXX81387.1 - 1.1e-08 33.3 31.3 1.1e-08 33.3 21.7 2.1 1 1 1 2 2 2 2 Myosin tail Filament PF00038.16 KXX81387.1 - 5e-07 29.4 93.4 9.3e-06 25.3 6.5 3.6 1 1 1 3 3 3 2 Intermediate filament protein Cortex-I_coil PF09304.5 KXX81387.1 - 1.6e-06 28.0 21.8 8.5e-05 22.5 6.8 8.0 2 2 2 6 6 4 3 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 KXX81387.1 - 2.7e-06 27.2 98.9 9.8e-06 25.4 1.9 7.4 1 1 7 8 8 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KXX81387.1 - 1.2e-05 23.9 9.0 1.2e-05 23.9 6.3 4.1 2 1 2 4 4 4 3 AAA domain CCDC155 PF14662.1 KXX81387.1 - 0.00016 21.3 7.9 0.00016 21.3 5.5 5.8 2 2 2 5 5 4 1 Coiled-coil region of CCDC155 IncA PF04156.9 KXX81387.1 - 0.00017 21.2 105.0 0.0014 18.3 11.3 7.3 1 1 5 6 6 5 4 IncA protein APG6 PF04111.7 KXX81387.1 - 0.0012 17.9 5.3 0.0012 17.9 3.7 6.3 1 1 5 6 6 6 3 Autophagy protein Apg6 DUF3584 PF12128.3 KXX81387.1 - 0.0091 13.3 101.2 0.0069 13.7 19.6 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 KXX81387.1 - 0.01 15.6 7.7 0.01 15.6 5.4 6.9 2 2 1 5 5 4 0 Tropomyosin like Baculo_PEP_C PF04513.7 KXX81387.1 - 0.049 13.4 39.0 0.86 9.4 1.3 6.8 4 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KXX81387.1 - 1.1 7.8 86.3 0.077 11.6 4.3 5.9 1 1 6 7 7 6 0 Spc7 kinetochore protein SnoaL_4 PF13577.1 KXX81388.1 - 7.6e-09 35.5 0.0 2.3e-08 34.0 0.0 1.8 1 1 1 2 2 2 1 SnoaL-like domain Arrestin_C PF02752.17 KXX81389.1 - 2.9e-16 59.7 0.0 1.1e-15 57.9 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KXX81389.1 - 3.6e-10 39.8 1.9 3.2e-06 27.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Nucleocapsid-N PF11030.3 KXX81389.1 - 0.097 12.4 3.4 0.22 11.3 2.4 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N Cyclin PF08613.6 KXX81390.1 - 2.1e-13 50.9 0.0 3.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KXX81390.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fungal_trans PF04082.13 KXX81391.1 - 3.5e-23 81.8 1.9 6.1e-23 81.0 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81391.1 - 7.6e-08 32.1 11.6 1.5e-07 31.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 KXX81391.1 - 0.14 12.1 0.8 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 PocR PF10114.4 KXX81391.1 - 0.24 10.5 2.2 0.39 9.8 1.5 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR Pox_A_type_inc PF04508.7 KXX81391.1 - 0.4 10.5 5.1 1 9.2 3.6 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Aldo_ket_red PF00248.16 KXX81392.1 - 2.1e-43 148.1 0.0 3e-35 121.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Abhydrolase_3 PF07859.8 KXX81393.1 - 6.6e-10 38.9 0.0 2.2e-09 37.2 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX81393.1 - 0.0029 16.3 0.0 0.003 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KXX81393.1 - 0.0069 15.6 0.0 0.032 13.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family PAE PF03283.8 KXX81393.1 - 0.019 13.6 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase FAA_hydrolase PF01557.13 KXX81393.1 - 0.15 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 KXX81394.1 - 1.4e-17 63.4 0.1 2.9e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PgaD PF13994.1 KXX81394.1 - 0.071 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 PgaD-like protein ABC_membrane PF00664.18 KXX81395.1 - 1.3e-81 274.0 32.4 2.1e-42 145.4 9.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KXX81395.1 - 9.5e-69 229.9 0.0 5.6e-33 114.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KXX81395.1 - 2.3e-15 56.4 2.2 1.7e-05 24.1 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KXX81395.1 - 2.6e-11 44.0 0.0 0.16 11.8 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KXX81395.1 - 7.5e-10 38.1 0.5 0.00032 20.1 0.2 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KXX81395.1 - 1.2e-09 37.3 3.3 0.00054 18.6 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KXX81395.1 - 7.4e-09 35.8 2.5 1.9e-05 24.7 0.2 2.7 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KXX81395.1 - 1.4e-08 34.0 0.5 0.0006 18.9 0.0 3.6 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 KXX81395.1 - 6.2e-08 32.8 1.0 0.0099 16.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX81395.1 - 1.1e-07 31.1 0.2 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KXX81395.1 - 9.8e-07 29.6 0.0 0.017 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KXX81395.1 - 3.3e-05 23.3 1.1 0.25 10.7 0.1 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KXX81395.1 - 0.00011 22.0 0.9 1.1 9.2 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KXX81395.1 - 0.00011 21.8 1.4 2 7.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KXX81395.1 - 0.00022 21.6 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KXX81395.1 - 0.00037 20.3 0.0 0.4 10.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.1 KXX81395.1 - 0.0004 20.2 0.0 0.45 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KXX81395.1 - 0.0013 18.4 0.0 1.4 8.7 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KXX81395.1 - 0.0016 18.1 0.2 1.4 8.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KXX81395.1 - 0.0017 17.4 0.0 0.99 8.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 KXX81395.1 - 0.0019 18.0 1.7 1.3 8.7 0.3 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 APS_kinase PF01583.15 KXX81395.1 - 0.0035 17.0 0.1 3.6 7.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 KXX81395.1 - 0.0038 16.9 0.2 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KXX81395.1 - 0.0047 17.1 0.2 6.7 6.9 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KXX81395.1 - 0.0048 16.4 0.1 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 KXX81395.1 - 0.0051 15.5 0.0 2.3 6.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.1 KXX81395.1 - 0.0051 17.1 0.0 3.4 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KXX81395.1 - 0.0096 14.8 0.5 1.9 7.2 0.1 2.7 3 0 0 3 3 3 1 NB-ARC domain PRK PF00485.13 KXX81395.1 - 0.012 15.1 0.2 0.87 9.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 KXX81395.1 - 0.013 14.9 3.9 2.1 7.7 0.2 3.7 4 0 0 4 4 4 0 AAA-like domain DUF815 PF05673.8 KXX81395.1 - 0.017 14.0 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KXX81395.1 - 0.018 15.0 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase KaiC PF06745.8 KXX81395.1 - 0.021 13.9 0.4 1.6 7.8 0.2 2.3 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 KXX81395.1 - 0.027 14.4 0.7 0.22 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX81395.1 - 0.032 13.7 0.1 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.10 KXX81395.1 - 0.062 11.9 0.1 0.12 10.9 0.0 1.4 2 0 0 2 2 1 0 Rad17 cell cycle checkpoint protein Miro PF08477.8 KXX81395.1 - 0.062 13.8 0.0 7.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KXX81395.1 - 0.072 12.7 0.4 11 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KXX81395.1 - 0.16 12.1 0.3 9.7 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase VirE PF05272.6 KXX81395.1 - 0.16 11.3 0.0 15 4.9 0.0 2.5 3 0 0 3 3 2 0 Virulence-associated protein E Glyco_hydro_61 PF03443.9 KXX81396.1 - 2.8e-43 148.2 0.0 3.2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Myb_DNA-binding PF00249.26 KXX81397.1 - 9.5e-31 105.6 9.0 2.8e-14 52.8 0.1 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX81397.1 - 1.9e-27 95.1 2.0 9e-13 48.1 0.2 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KXX81397.1 - 0.00048 20.2 5.2 3.7 7.7 0.5 3.8 3 1 0 3 3 3 3 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KXX81397.1 - 0.0012 18.5 1.9 7.4 6.4 0.1 3.5 2 1 1 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.3 KXX81397.1 - 0.14 12.0 3.7 11 5.9 1.2 3.5 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 KXX81397.1 - 0.17 12.0 3.4 4.9 7.4 0.1 2.8 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 KXX81397.1 - 0.97 9.3 12.4 4.8 7.1 0.5 4.0 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain peroxidase PF00141.18 KXX81398.1 - 3.3e-86 288.5 0.0 4.6e-45 153.8 0.0 2.3 2 0 0 2 2 2 2 Peroxidase GST_C PF00043.20 KXX81398.1 - 0.037 14.0 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain 5_nucleotid_C PF02872.13 KXX81399.1 - 7.6e-31 107.2 0.0 1.4e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KXX81399.1 - 3.5e-11 42.8 0.3 3.1e-10 39.7 0.2 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 KXX81399.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein PGA_cap PF09587.5 KXX81399.1 - 0.083 12.2 0.1 0.25 10.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Peptidase_M28 PF04389.12 KXX81400.1 - 1e-30 106.7 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KXX81400.1 - 1.4e-16 60.0 0.0 2.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KXX81400.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3938 PF13074.1 KXX81401.1 - 0.057 13.2 2.8 0.057 13.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF420 PF04238.7 KXX81401.1 - 0.21 11.5 6.5 0.44 10.5 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Rhodanese PF00581.15 KXX81402.1 - 3.2e-27 95.1 0.0 1.7e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain adh_short PF00106.20 KXX81404.1 - 7.5e-15 55.2 0.2 2e-14 53.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX81404.1 - 1.9e-07 30.9 0.1 2.9e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX81404.1 - 0.0041 16.8 0.1 0.0092 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KXX81404.1 - 0.03 13.7 0.1 0.11 11.8 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CPDase PF07823.6 KXX81404.1 - 0.035 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein FAD_binding_4 PF01565.18 KXX81405.1 - 3.3e-17 62.2 0.4 7.9e-17 61.0 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX81405.1 - 2.2e-07 30.6 0.0 4.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.2 KXX81406.1 - 1.1e-78 259.5 5.5 3.8e-20 72.0 0.1 7.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX81406.1 - 4.9e-66 217.2 8.0 2.7e-10 40.1 0.0 11.0 3 1 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.25 KXX81406.1 - 1e-60 198.6 9.9 4.1e-07 29.4 0.0 12.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 KXX81406.1 - 2.9e-56 186.9 7.8 1.2e-10 41.5 0.0 10.8 5 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81406.1 - 5.1e-44 143.8 3.2 5.2e-05 23.0 0.0 12.8 12 0 0 12 12 12 9 Ankyrin repeat SPRY PF00622.23 KXX81406.1 - 0.0024 17.9 0.2 0.006 16.6 0.1 1.6 1 0 0 1 1 1 1 SPRY domain DUF2306 PF10067.4 KXX81407.1 - 6.9e-12 45.3 9.9 6.9e-12 45.3 6.8 2.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) Ribosomal_L19e PF01280.15 KXX81409.1 - 3.4e-61 205.3 7.8 3.4e-61 205.3 5.4 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 KXX81409.1 - 0.093 11.9 0.6 0.089 11.9 0.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4337 PF14235.1 KXX81409.1 - 7.4 6.3 7.9 11 5.8 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SHMT PF00464.14 KXX81410.1 - 2.8e-196 651.6 0.0 3.3e-196 651.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KXX81410.1 - 7.6e-06 25.2 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KXX81410.1 - 0.0042 15.8 0.0 0.0071 15.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V HA2 PF04408.18 KXX81411.1 - 1.6e-16 60.1 0.0 6e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KXX81411.1 - 1.8e-12 46.9 0.1 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX81411.1 - 3.7e-10 39.5 0.0 6.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX81411.1 - 1.1e-08 35.2 0.2 8.5e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 KXX81411.1 - 3.6e-07 30.0 0.0 8.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 KXX81411.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KXX81411.1 - 0.0086 16.3 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter KaiC PF06745.8 KXX81411.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF87 PF01935.12 KXX81411.1 - 0.15 11.8 2.8 52 3.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF258 PF03193.11 KXX81411.1 - 0.17 11.0 0.0 0.45 9.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX81411.1 - 0.71 10.1 7.3 0.75 10.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF3554 PF12074.3 KXX81412.1 - 2.3e-88 296.9 9.5 4.6e-88 295.9 0.0 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF3554) HEAT PF02985.17 KXX81412.1 - 1e-42 140.3 35.1 0.0067 16.4 0.0 23.0 26 0 0 26 26 24 11 HEAT repeat HEAT_2 PF13646.1 KXX81412.1 - 6.9e-40 135.2 58.8 3e-10 40.2 0.0 16.8 8 3 6 14 14 14 9 HEAT repeats HEAT_EZ PF13513.1 KXX81412.1 - 4.1e-30 103.4 78.9 2.7e-06 27.6 0.0 23.9 21 3 7 28 28 25 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KXX81412.1 - 1e-15 57.8 0.0 0.38 11.1 0.0 10.4 9 3 3 12 12 10 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KXX81412.1 - 1e-14 54.4 0.0 0.0072 15.7 0.0 6.6 4 1 4 8 8 8 4 CLASP N terminal ParcG PF10274.4 KXX81412.1 - 7.1e-12 45.5 0.9 0.0002 21.2 0.0 5.2 4 1 0 4 4 4 3 Parkin co-regulated protein Cnd1 PF12717.2 KXX81412.1 - 8.4e-12 45.2 0.4 0.37 10.6 0.2 9.5 6 3 3 10 10 10 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KXX81412.1 - 6.7e-08 32.4 0.1 43 4.1 0.0 8.7 7 2 2 10 10 9 0 UME (NUC010) domain Ipi1_N PF12333.3 KXX81412.1 - 4e-06 26.7 0.2 0.0025 17.7 0.1 5.3 5 0 0 5 5 4 1 Rix1 complex component involved in 60S ribosome maturation DUF3535 PF12054.3 KXX81412.1 - 0.007 15.0 1.6 0.17 10.4 0.0 3.8 4 2 0 5 5 5 1 Domain of unknown function (DUF3535) RIX1 PF08167.7 KXX81412.1 - 0.036 13.7 9.5 3.9 7.1 0.1 6.6 6 1 1 7 7 7 0 rRNA processing/ribosome biogenesis DUF2454 PF10521.4 KXX81412.1 - 0.048 12.6 0.9 2.2 7.2 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2454) Arm PF00514.18 KXX81412.1 - 0.17 11.7 17.9 3.4 7.6 0.0 9.6 11 1 1 12 12 11 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 KXX81412.1 - 0.28 9.8 12.5 1.4 7.5 0.2 5.8 6 1 1 7 7 7 0 RNAPII transcription regulator C-terminal DUF3896 PF13035.1 KXX81412.1 - 5.1 7.2 3.6 12 6.0 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) SURNod19 PF07712.7 KXX81414.1 - 6.1e-05 21.6 0.6 0.00012 20.6 0.4 1.5 1 1 0 1 1 1 1 Stress up-regulated Nod 19 COesterase PF00135.23 KXX81416.1 - 4.6e-69 233.5 0.0 1.2e-68 232.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX81416.1 - 7e-08 32.2 3.2 8.7e-07 28.7 2.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX81416.1 - 0.0031 16.2 0.0 0.93 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) UbiD PF01977.11 KXX81416.1 - 0.071 11.5 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Abhydrolase_5 PF12695.2 KXX81416.1 - 0.078 12.7 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.5 KXX81416.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Hydrolase_6 PF13344.1 KXX81417.1 - 3.4e-22 78.2 0.0 9.4e-22 76.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX81417.1 - 6.1e-11 41.8 0.0 2.5e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KXX81417.1 - 0.026 14.9 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PTE PF02126.13 KXX81417.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family HAD_2 PF13419.1 KXX81417.1 - 0.14 12.3 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4360 PF14273.1 KXX81419.1 - 9.3e-45 152.5 1.0 1.1e-44 152.2 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.17 KXX81420.1 - 8.2e-43 143.9 0.2 6.2e-15 54.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX81420.1 - 4.9e-39 132.1 0.2 7.3e-16 57.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX81420.1 - 5.8e-23 80.5 0.1 2.1e-09 37.0 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KXX81420.1 - 1.9e-08 33.9 0.0 0.0045 16.7 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KXX81420.1 - 0.0013 18.5 0.1 0.029 14.2 0.0 3.0 2 1 1 3 3 3 1 RNA binding motif Lsm_interact PF05391.6 KXX81420.1 - 0.0028 17.0 0.5 0.0069 15.7 0.3 1.7 1 0 0 1 1 1 1 Lsm interaction motif Limkain-b1 PF11608.3 KXX81420.1 - 0.059 13.1 0.4 24 4.7 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 WD40 PF00400.27 KXX81422.1 - 6.1e-20 70.2 5.9 2.9e-11 42.7 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 KXX81422.1 - 2.3e-18 66.0 0.0 4.3e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily DUF1513 PF07433.6 KXX81422.1 - 0.0075 15.2 0.1 0.72 8.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 KXX81422.1 - 0.059 11.6 0.0 0.35 9.1 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain GMC_oxred_N PF00732.14 KXX81423.1 - 1.9e-59 201.2 0.0 2.8e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX81423.1 - 6.8e-32 110.7 0.0 1.3e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX81423.1 - 4.6e-07 29.0 0.0 0.00083 18.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX81423.1 - 7.6e-05 22.6 0.0 0.00029 20.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KXX81423.1 - 0.00012 22.2 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX81423.1 - 0.0032 16.3 0.1 0.032 13.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KXX81423.1 - 0.0039 16.3 0.0 0.0039 16.3 0.0 1.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 KXX81423.1 - 0.011 15.6 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX81423.1 - 0.015 14.2 0.1 0.051 12.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KXX81423.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KXX81423.1 - 0.11 10.8 0.0 0.23 9.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein RTA1 PF04479.8 KXX81424.1 - 8.6e-08 31.9 9.7 2e-07 30.7 5.5 2.2 1 1 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.1 KXX81424.1 - 0.3 11.1 13.3 0.085 12.9 3.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) Glyco_hydro_16 PF00722.16 KXX81425.1 - 5.3e-17 61.7 0.0 9.3e-17 60.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KXX81425.1 - 4e-05 21.9 0.1 0.018 13.2 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Effector_1 PF04518.7 KXX81425.1 - 0.081 11.8 0.4 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF2401 PF10287.4 KXX81425.1 - 0.14 11.5 0.1 0.37 10.2 0.1 1.5 1 1 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Peptidase_S8 PF00082.17 KXX81427.1 - 9.1e-48 162.8 8.8 1.2e-47 162.4 6.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KXX81427.1 - 5.1e-13 49.3 0.2 9.1e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 PDGLE PF13190.1 KXX81429.1 - 0.061 12.9 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 PDGLE domain Methyltransf_11 PF08241.7 KXX81430.1 - 0.0012 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81430.1 - 0.065 12.8 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF1237 PF06824.6 KXX81431.1 - 1.4e-175 583.9 0.0 1.7e-175 583.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) zf-CCHC PF00098.18 KXX81433.1 - 7.6e-42 139.3 55.8 2.2e-07 30.4 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KXX81433.1 - 2.9e-10 39.6 46.8 0.0088 15.6 0.3 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KXX81433.1 - 0.00055 19.6 44.6 0.59 9.9 1.0 7.0 4 2 2 6 6 6 4 Zinc knuckle Form_Nir_trans PF01226.12 KXX81434.1 - 0.099 11.5 1.0 0.14 10.9 0.7 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter FAD_binding_3 PF01494.14 KXX81435.1 - 2.6e-17 62.9 0.0 8.5e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KXX81435.1 - 2.4e-05 23.4 0.1 0.0011 17.9 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX81435.1 - 5.3e-05 23.0 0.0 0.0008 19.2 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KXX81435.1 - 0.00039 20.3 1.2 0.0013 18.7 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KXX81435.1 - 0.013 14.3 0.0 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 KXX81435.1 - 0.019 13.6 0.1 4.2 5.8 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_4 PF01565.18 KXX81436.1 - 3.8e-16 58.8 1.6 7.7e-16 57.8 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX81436.1 - 1.6e-06 27.8 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like WD40 PF00400.27 KXX81439.1 - 2.9e-55 182.2 4.4 1.2e-09 37.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KXX81439.1 - 0.0064 15.2 1.1 0.55 8.9 0.6 3.3 1 1 1 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 KXX81440.1 - 8.2e-36 122.8 0.0 9.6e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4360 PF14273.1 KXX81441.1 - 9.3e-13 48.2 0.0 9.9e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CFEM PF05730.6 KXX81442.1 - 1.9e-10 40.4 4.3 3.3e-10 39.6 3.0 1.4 1 0 0 1 1 1 1 CFEM domain Podoplanin PF05808.6 KXX81442.1 - 0.0048 16.4 6.1 0.0065 16.0 4.2 1.2 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.11 KXX81442.1 - 0.01 14.1 0.8 0.014 13.6 0.0 1.6 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KXX81442.1 - 0.069 12.4 0.7 0.16 11.3 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RCR PF12273.3 KXX81442.1 - 0.19 12.2 0.0 0.19 12.2 0.0 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF566 PF04484.7 KXX81442.1 - 0.34 10.3 8.9 0.43 10.0 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SOG2 PF10428.4 KXX81442.1 - 7.4 5.1 16.4 10 4.6 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.27 KXX81443.1 - 7.8e-62 203.1 24.3 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KXX81443.1 - 3.3e-06 25.5 5.9 0.16 10.0 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KXX81443.1 - 0.034 12.4 0.0 4.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Bromo_TP PF07524.8 KXX81444.1 - 8.5e-18 63.8 0.0 1.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KXX81444.1 - 5.8e-10 39.0 2.1 6.3e-05 22.9 0.4 2.6 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term LRR_4 PF12799.2 KXX81445.1 - 6.6e-17 60.7 0.0 0.00021 20.8 0.0 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX81445.1 - 1.9e-13 49.9 0.2 1.9e-06 27.5 0.1 3.8 1 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 KXX81445.1 - 1.2e-12 45.9 0.0 0.12 12.5 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich Repeat Pkinase_Tyr PF07714.12 KXX81445.1 - 3e-11 42.8 0.0 1.9e-09 36.9 0.0 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KXX81445.1 - 1.7e-09 37.2 0.0 3.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_7 PF13504.1 KXX81445.1 - 0.00013 21.5 5.6 6.4 7.4 0.1 5.9 7 0 0 7 7 7 1 Leucine rich repeat Kdo PF06293.9 KXX81445.1 - 0.00019 20.5 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 KXX81445.1 - 0.071 13.2 0.9 82 3.7 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.1 KXX81445.1 - 0.083 12.4 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeat Isochorismatase PF00857.15 KXX81446.1 - 9.2e-28 97.3 0.1 5.4e-27 94.8 0.1 2.2 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KXX81446.1 - 1.3e-26 93.6 0.0 2.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KXX81446.1 - 0.0017 18.8 0.0 0.0071 16.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX81446.1 - 0.042 13.7 3.8 0.18 11.6 2.6 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3185 PF11381.3 KXX81446.1 - 0.13 12.0 0.1 20 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Ribosomal_L22 PF00237.14 KXX81447.1 - 4.3e-14 52.3 1.1 1.2e-05 25.1 0.0 2.6 3 0 0 3 3 3 2 Ribosomal protein L22p/L17e DUF3112 PF11309.3 KXX81448.1 - 5.3e-49 166.0 7.4 3.4e-48 163.4 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) DUF1418 PF07214.7 KXX81448.1 - 0.081 12.5 7.6 1.1 8.9 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF4059 PF13268.1 KXX81448.1 - 0.29 11.3 6.7 1.7 8.9 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4059) DUF3311 PF11755.3 KXX81448.1 - 0.61 9.6 6.6 0.85 9.1 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3311) APH PF01636.18 KXX81450.1 - 1.6e-06 28.0 1.1 5.9e-06 26.1 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX81450.1 - 0.099 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase MFS_1 PF07690.11 KXX81451.1 - 2.3e-17 62.7 20.2 8.7e-16 57.5 7.6 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily Secretin PF00263.16 KXX81453.1 - 0.061 12.7 0.1 0.073 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein TPR_11 PF13414.1 KXX81454.1 - 8.8e-17 60.5 0.2 1e-11 44.2 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KXX81454.1 - 3.5e-13 48.3 7.1 8.7e-05 22.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX81454.1 - 4e-12 45.2 2.6 0.00042 19.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KXX81454.1 - 2.4e-08 33.8 0.3 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KXX81454.1 - 8.1e-08 31.5 0.3 0.069 12.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX81454.1 - 2.2e-07 31.3 4.6 1.1e-05 26.0 0.4 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KXX81454.1 - 4.6e-05 23.1 1.6 0.05 13.4 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81454.1 - 8e-05 22.9 2.3 0.085 13.5 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX81454.1 - 0.00028 21.1 0.2 0.0055 17.0 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX81454.1 - 0.00034 20.1 1.6 0.43 10.4 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KXX81454.1 - 0.0022 18.2 1.0 0.32 11.5 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KXX81454.1 - 0.0036 17.3 1.2 0.15 12.3 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX81454.1 - 0.014 15.8 3.5 3 8.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KXX81454.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KXX81454.1 - 0.049 13.5 3.1 5.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX81454.1 - 0.28 11.0 1.4 6.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TauD PF02668.11 KXX81456.1 - 1.3e-28 100.4 0.0 1.7e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX81456.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 CsiD MFS_1 PF07690.11 KXX81457.1 - 1.6e-27 96.1 41.0 1.6e-27 96.1 28.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyltransferase PF01553.16 KXX81458.1 - 1.7e-24 85.7 0.0 2.5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GST_N_2 PF13409.1 KXX81459.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KXX81459.1 - 0.00036 20.6 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KXX81459.1 - 0.005 16.9 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 KXX81460.1 - 3.4e-42 144.5 0.0 3.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KXX81461.1 - 3e-23 82.0 0.0 5e-23 81.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KXX81461.1 - 0.0084 14.6 0.1 0.012 14.2 0.1 1.2 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.13 KXX81462.1 - 9.8e-36 123.1 0.0 1.3e-34 119.4 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 KXX81462.1 - 0.029 14.1 0.1 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_18 PF12847.2 KXX81462.1 - 0.066 13.7 0.0 0.27 11.8 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain AAA_33 PF13671.1 KXX81462.1 - 0.15 11.9 1.3 0.26 11.1 0.3 1.8 2 0 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.1 KXX81463.1 - 1.1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81463.1 - 9.4e-07 29.2 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81463.1 - 4.4e-06 27.2 0.0 1.6e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81463.1 - 1.1e-05 25.1 0.0 0.00015 21.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81463.1 - 0.0003 21.2 0.0 0.00072 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81463.1 - 0.00062 20.0 0.0 0.013 15.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81463.1 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KXX81463.1 - 0.02 14.8 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase MBOAT_2 PF13813.1 KXX81464.1 - 1.2e-19 70.1 4.7 3e-19 68.8 3.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 KXX81465.1 - 1.3e-64 218.4 0.0 1.5e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2762 PF10960.3 KXX81465.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DUF92 PF01940.11 KXX81465.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 Methyltransf_23 PF13489.1 KXX81466.1 - 4.7e-14 52.4 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81466.1 - 1e-13 51.5 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81466.1 - 1.3e-10 41.6 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81466.1 - 2.9e-09 37.2 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81466.1 - 3.2e-09 36.5 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81466.1 - 6.1e-09 35.3 0.0 5.4e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KXX81466.1 - 8e-08 32.8 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81466.1 - 4.9e-06 26.5 0.5 1.2e-05 25.3 0.4 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX81466.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX81466.1 - 0.00047 20.1 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PepSY_2 PF13670.1 KXX81466.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.4 3 0 0 3 3 3 1 Peptidase propeptide and YPEB domain MTS PF05175.9 KXX81466.1 - 0.0072 15.7 0.1 1.2 8.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase small domain PCMT PF01135.14 KXX81466.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_2 PF07992.9 KXX81467.1 - 2e-11 44.1 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX81467.1 - 1.1e-06 27.7 0.0 1.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX81467.1 - 3.7e-05 22.8 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KXX81467.1 - 0.00016 20.6 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KXX81467.1 - 0.00022 20.4 0.1 0.00041 19.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KXX81467.1 - 0.00051 20.1 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX81467.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX81467.1 - 0.0019 18.1 0.1 0.0046 16.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX81467.1 - 0.002 16.6 0.0 0.0036 15.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KXX81467.1 - 0.017 14.2 0.2 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX81467.1 - 0.037 14.2 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX81467.1 - 0.039 12.8 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KXX81467.1 - 0.11 11.4 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KXX81467.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.8 1 1 1 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 KXX81469.1 - 7.1e-11 41.4 2.5 1.7e-10 40.2 1.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81469.1 - 2.3e-10 40.2 10.0 3.9e-10 39.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.7 KXX81471.1 - 9.2e-55 183.7 2.9 1.1e-54 183.5 2.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Ribonuclease_T2 PF00445.13 KXX81472.1 - 4.6e-35 120.9 0.0 6.2e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ADH_zinc_N_2 PF13602.1 KXX81472.1 - 0.033 15.1 0.0 0.054 14.3 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 4HBT_2 PF13279.1 KXX81473.1 - 1.2e-20 74.1 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KXX81473.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily GAS PF13851.1 KXX81474.1 - 0.43 9.7 20.5 1.5 7.9 10.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KXX81474.1 - 1.4 8.9 24.1 0.43 10.6 2.5 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Exo_endo_phos PF03372.18 KXX81475.1 - 9.6e-26 91.2 0.2 1.4e-25 90.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KXX81475.1 - 1.9e-13 49.7 7.5 9.1e-08 31.5 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX81475.1 - 1.2e-07 31.4 16.3 2.8e-05 23.7 1.2 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KXX81475.1 - 6.9e-05 22.3 4.6 0.76 10.0 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KXX81475.1 - 0.0027 17.6 6.1 4.1 8.0 0.0 4.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KXX81475.1 - 0.27 11.4 1.2 9.8 6.6 0.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Methyltransf_25 PF13649.1 KXX81476.1 - 2.4e-09 37.4 0.0 5.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81476.1 - 8.7e-08 32.5 0.0 2.6e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81476.1 - 1.7e-06 27.8 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81476.1 - 2.4e-05 24.8 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81476.1 - 3.8e-05 23.3 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81476.1 - 0.00017 21.6 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81476.1 - 0.004 16.3 0.0 0.056 12.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KXX81476.1 - 0.0097 16.3 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KXX81476.1 - 0.045 13.4 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KXX81476.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CFEM PF05730.6 KXX81477.1 - 2.3e-10 40.1 9.6 3.5e-10 39.5 6.7 1.2 1 0 0 1 1 1 1 CFEM domain NAD_kinase PF01513.16 KXX81478.1 - 2.5e-47 161.0 0.0 1.3e-46 158.6 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase Methyltransf_11 PF08241.7 KXX81479.1 - 5.1e-10 39.7 0.0 9.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81479.1 - 3.2e-06 27.4 0.0 5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81479.1 - 0.00096 19.1 0.1 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81479.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81479.1 - 0.0024 17.6 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81479.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KXX81479.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.8 KXX81480.1 - 3.1e-24 85.5 0.7 3.9e-24 85.1 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX81480.1 - 3.2e-14 53.3 0.4 6.8e-14 52.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX81480.1 - 0.0017 17.4 0.2 0.014 14.3 0.0 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KXX81480.1 - 0.0034 16.8 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family LuxQ-periplasm PF09308.5 KXX81480.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic TauD PF02668.11 KXX81481.1 - 1.3e-30 106.9 0.0 1.6e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX81481.1 - 0.0013 17.7 0.1 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 CsiD Acetyltransf_1 PF00583.19 KXX81484.1 - 0.0052 16.7 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KXX81484.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Virul_fac_BrkB PF03631.10 KXX81485.1 - 0.095 12.0 10.2 0.018 14.4 4.1 1.9 1 1 1 2 2 2 0 Virulence factor BrkB Methyltransf_23 PF13489.1 KXX81487.1 - 6e-07 29.3 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SRP54_N PF02881.14 KXX81487.1 - 0.039 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Methyltransf_31 PF13847.1 KXX81487.1 - 0.096 12.2 0.0 0.74 9.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KXX81488.1 - 4.8e-19 69.0 0.4 7e-19 68.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX81488.1 - 2.1e-07 30.1 0.0 5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX81488.1 - 4.3e-06 25.8 6.6 1e-05 24.6 0.4 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX81488.1 - 4.5e-06 25.3 0.0 7.4e-05 21.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KXX81488.1 - 7.5e-06 25.0 0.5 0.001 18.0 0.4 2.2 1 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KXX81488.1 - 8.7e-06 25.5 0.7 0.12 12.1 0.0 2.4 1 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KXX81488.1 - 1.1e-05 25.6 0.1 0.019 14.9 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX81488.1 - 3.3e-05 23.1 0.2 6e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX81488.1 - 6.1e-05 22.9 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX81488.1 - 0.00035 19.7 0.1 0.00095 18.3 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KXX81488.1 - 0.00084 18.5 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KXX81488.1 - 0.0015 18.7 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KXX81488.1 - 0.0042 16.0 0.2 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KXX81488.1 - 0.019 13.6 0.1 0.029 12.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KXX81488.1 - 0.041 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyltransferase PF01553.16 KXX81489.1 - 0.003 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 KXX81490.1 - 1.1e-104 349.7 0.3 1.1e-104 349.7 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 KXX81490.1 - 6.2e-07 28.2 45.3 1.4e-06 27.1 31.4 1.5 1 0 0 1 1 1 1 Weak chloroplast movement under blue light MiaE_2 PF13794.1 KXX81490.1 - 0.007 15.8 1.4 0.014 14.9 1.0 1.5 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Reo_sigmaC PF04582.7 KXX81490.1 - 9 5.3 11.4 0.66 9.1 1.9 2.5 2 1 0 3 3 3 0 Reovirus sigma C capsid protein CLP_protease PF00574.18 KXX81491.1 - 3.8e-68 228.7 0.1 5e-68 228.3 0.1 1.1 1 0 0 1 1 1 1 Clp protease Phage_NinH PF06322.6 KXX81491.1 - 0.078 12.6 0.1 0.98 9.0 0.1 2.3 2 0 0 2 2 2 0 Phage NinH protein ILVD_EDD PF00920.16 KXX81492.1 - 7.2e-209 694.5 0.2 8.3e-209 694.3 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family DNA_primase_lrg PF04104.9 KXX81493.1 - 3.6e-80 268.9 0.0 5.3e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Thioesterase PF00975.15 KXX81495.1 - 3.5e-13 50.3 0.0 2.3e-12 47.6 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KXX81495.1 - 8.4e-09 35.6 0.0 2.5e-08 34.1 0.0 1.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX81495.1 - 0.0075 15.7 0.1 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KXX81495.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PS_Dcarbxylase PF02666.10 KXX81496.1 - 1.9e-48 164.4 0.1 2.3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FAD_binding_3 PF01494.14 KXX81498.1 - 8.6e-72 242.1 0.0 2.2e-71 240.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX81498.1 - 7.8e-06 25.0 1.8 0.0004 19.4 0.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX81498.1 - 0.00033 20.7 0.1 0.0018 18.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX81498.1 - 0.0012 17.8 0.1 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KXX81498.1 - 0.0021 18.4 0.1 0.57 10.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX81498.1 - 0.0061 16.4 0.7 0.015 15.1 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX81498.1 - 0.0066 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KXX81498.1 - 0.0069 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.7 KXX81498.1 - 0.02 13.7 0.4 0.064 12.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KXX81498.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KXX81498.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KXX81498.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KXX81498.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CAP PF00188.21 KXX81500.1 - 1.3e-17 64.4 0.3 1.8e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Complex1_LYR PF05347.10 KXX81501.1 - 1.2e-06 28.1 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX81501.1 - 5.6e-06 26.4 0.6 2.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Complex1_LYR-like UQ_con PF00179.21 KXX81502.1 - 1.1e-13 50.7 0.1 1.9e-13 50.0 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KXX81502.1 - 0.0049 16.7 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain DUF4582 PF15189.1 KXX81502.1 - 0.012 14.9 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Pkinase PF00069.20 KXX81503.1 - 1.3e-36 126.0 0.0 3.2e-35 121.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81503.1 - 1.1e-23 83.7 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-F_N PF10481.4 KXX81503.1 - 0.0084 15.5 1.0 0.0084 15.5 0.7 2.2 3 0 0 3 3 3 1 Cenp-F N-terminal domain PAT1 PF09770.4 KXX81503.1 - 0.011 14.0 8.1 0.016 13.5 5.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kdo PF06293.9 KXX81503.1 - 0.018 14.1 1.9 0.018 14.1 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CALCOCO1 PF07888.6 KXX81503.1 - 0.051 11.8 5.5 0.084 11.1 3.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GBP_C PF02841.9 KXX81503.1 - 0.18 10.9 2.8 0.29 10.2 2.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Flu_PB2 PF00604.12 KXX81503.1 - 0.28 8.9 1.2 0.4 8.4 0.9 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 DivIC PF04977.10 KXX81503.1 - 2.8 7.5 7.4 4.1 6.9 4.3 1.8 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KXX81503.1 - 4.2 6.3 5.5 7.4 5.5 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 KXX81504.1 - 3.5e-07 30.0 0.9 6.2e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor PilO PF04350.8 KXX81504.1 - 0.054 13.3 0.3 0.094 12.6 0.2 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO Herpes_pp85 PF04637.7 KXX81504.1 - 0.23 9.7 1.9 0.36 9.0 1.3 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) bZIP_2 PF07716.10 KXX81504.1 - 0.42 10.4 5.9 0.45 10.3 2.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Methyltransf_31 PF13847.1 KXX81505.1 - 2.9e-27 95.1 0.0 4.1e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81505.1 - 4.4e-16 59.1 0.0 8.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81505.1 - 1.2e-12 47.4 0.0 1.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KXX81505.1 - 1.6e-10 41.5 0.0 2.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81505.1 - 1.7e-10 41.1 0.0 3.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81505.1 - 1.7e-10 40.8 0.0 2.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81505.1 - 2.9e-09 37.2 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81505.1 - 1.7e-08 34.4 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KXX81505.1 - 7.8e-05 22.2 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KXX81505.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KXX81505.1 - 0.0043 16.7 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX81505.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 KXX81505.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.15 KXX81505.1 - 0.038 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 KXX81505.1 - 0.16 10.9 0.0 0.39 9.7 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_9 PF08003.6 KXX81505.1 - 0.21 10.2 0.0 0.74 8.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) DUF3437 PF11919.3 KXX81506.1 - 7.7e-32 108.8 0.3 3.7e-31 106.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KXX81506.1 - 0.036 14.1 2.6 18 5.7 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Glyoxalase_2 PF12681.2 KXX81507.1 - 4.7e-12 46.4 0.2 5.5e-12 46.2 0.2 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KXX81507.1 - 1.7e-08 34.5 0.1 2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CENP-F_leu_zip PF10473.4 KXX81508.1 - 0.047 13.5 0.5 0.074 12.9 0.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CHAT PF12770.2 KXX81509.1 - 6.2e-29 101.0 0.0 1.2e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_19 PF14559.1 KXX81509.1 - 5e-07 29.9 0.1 1.8 8.9 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Peptidase_C50 PF03568.12 KXX81509.1 - 1e-05 24.4 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_14 PF13428.1 KXX81509.1 - 0.0071 16.8 11.2 8.9 7.2 0.1 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX81509.1 - 0.0081 16.2 3.8 5 7.3 0.1 5.1 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Apc5 PF12862.2 KXX81509.1 - 0.36 10.6 3.6 1.4 8.8 0.1 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 S1FA PF04689.8 KXX81510.1 - 0.027 14.3 0.6 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA Yip1 PF04893.12 KXX81510.1 - 2.9 7.3 15.9 0.11 12.0 0.2 3.9 4 0 0 4 4 4 0 Yip1 domain AAA PF00004.24 KXX81511.1 - 0.00053 20.2 0.0 0.0024 18.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CorA PF01544.13 KXX81511.1 - 0.0037 16.3 2.9 0.015 14.3 0.8 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein PGG PF13962.1 KXX81511.1 - 0.033 13.7 0.2 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function AAA_5 PF07728.9 KXX81511.1 - 0.034 13.8 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KXX81511.1 - 0.08 13.0 0.1 0.85 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KXX81511.1 - 0.096 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF3784 PF12650.2 KXX81511.1 - 0.11 12.4 0.7 0.27 11.1 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF2884 PF11101.3 KXX81511.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) GMC_oxred_N PF00732.14 KXX81512.1 - 1.1e-55 188.9 0.0 1.5e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX81512.1 - 7.5e-41 139.7 0.0 1.3e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX81512.1 - 1.1e-05 24.4 0.2 0.0023 16.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX81512.1 - 3.2e-05 23.0 0.1 5.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX81512.1 - 0.0093 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX81512.1 - 0.023 13.5 0.2 0.43 9.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KXX81512.1 - 0.035 13.9 0.2 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CorA PF01544.13 KXX81513.1 - 2.9e-07 29.8 0.0 3.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2899 PF11449.3 KXX81513.1 - 0.026 13.6 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF2909 PF11137.3 KXX81513.1 - 0.51 10.1 11.4 1.9 8.2 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2909) DUF3366 PF11846.3 KXX81513.1 - 0.86 9.4 3.6 0.96 9.2 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) MS_channel PF00924.13 KXX81514.1 - 4.8e-14 52.1 0.6 9.5e-14 51.2 0.0 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel XkdW PF09636.5 KXX81514.1 - 0.33 10.8 1.6 3.2 7.6 0.7 2.2 2 0 0 2 2 2 0 XkdW protein Nup96 PF12110.3 KXX81515.1 - 0.029 13.5 0.9 0.038 13.1 0.6 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Allexi_40kDa PF05549.6 KXX81515.1 - 0.03 13.6 0.2 0.031 13.5 0.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein NAD_binding_10 PF13460.1 KXX81516.1 - 4.8e-10 39.7 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX81516.1 - 1.8e-07 30.7 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KXX81516.1 - 1.3e-06 27.6 0.0 1.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 KXX81516.1 - 0.00039 20.9 0.0 0.00066 20.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 KXX81516.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KXX81516.1 - 0.046 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 KXX81516.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Esterase PF00756.15 KXX81517.1 - 4.3e-16 59.0 0.2 1.1e-14 54.4 0.1 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KXX81517.1 - 0.11 12.3 0.1 0.33 10.7 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Band_7 PF01145.20 KXX81519.1 - 7.1e-31 107.4 0.8 1.4e-30 106.5 0.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KXX81519.1 - 0.042 13.3 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sec7_N PF12783.2 KXX81520.1 - 1.3e-35 122.2 2.3 4.1e-34 117.4 0.0 3.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KXX81520.1 - 2.6e-06 26.8 1.3 0.00015 21.1 0.0 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.3 KXX81520.1 - 1.4 8.8 5.9 0.73 9.8 0.2 3.5 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Peptidase_M20 PF01546.23 KXX81521.1 - 8.2e-23 80.8 0.0 1.8e-22 79.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KXX81521.1 - 1.6e-18 65.8 5.1 6.5e-05 22.6 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.9 KXX81521.1 - 2.9e-06 26.9 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3639 PF12341.3 KXX81521.1 - 0.014 15.4 0.1 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Peptidase_M28 PF04389.12 KXX81521.1 - 0.035 13.8 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PQQ_3 PF13570.1 KXX81521.1 - 0.089 13.0 0.7 2.9 8.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain Tim17 PF02466.14 KXX81522.1 - 1.3e-24 86.6 8.9 4.7e-24 84.8 6.2 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.2 KXX81523.1 - 5.5e-29 100.3 0.7 5.3e-14 52.3 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX81523.1 - 1.5e-28 97.1 0.5 4.1e-08 32.6 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KXX81523.1 - 1.6e-25 88.9 1.8 3.7e-08 33.6 0.0 5.5 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX81523.1 - 6.3e-23 80.2 1.3 5e-07 29.7 0.1 6.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81523.1 - 5.4e-18 63.2 0.0 6.7e-06 25.8 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Cas_VVA1548 PF09652.5 KXX81523.1 - 0.013 15.4 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) Chitin_bind_1 PF00187.14 KXX81524.1 - 3.2 7.8 24.6 4 7.4 15.8 2.1 1 1 1 2 2 2 0 Chitin recognition protein Cupin_2 PF07883.6 KXX81525.1 - 2.4e-08 33.3 0.0 4.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KXX81525.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KXX81525.1 - 0.0034 16.7 0.0 0.0074 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) BBS2_Mid PF14783.1 KXX81525.1 - 0.024 14.4 0.1 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Lactamase_B_2 PF12706.2 KXX81526.1 - 1.3e-27 96.6 5.8 4.6e-27 94.8 4.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KXX81526.1 - 3.3e-06 26.9 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX81526.1 - 0.00072 19.2 0.2 0.024 14.2 0.4 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Asparaginase_2 PF01112.13 KXX81527.1 - 4.1e-42 144.0 0.0 7.5e-19 67.5 0.0 3.2 3 0 0 3 3 3 3 Asparaginase Pkinase PF00069.20 KXX81529.1 - 5.7e-48 163.3 0.0 7.2e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain YTH PF04146.10 KXX81529.1 - 3.1e-28 98.1 0.0 1.1e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 YT521-B-like domain Pkinase_Tyr PF07714.12 KXX81529.1 - 7.2e-23 80.9 0.0 1.1e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX81529.1 - 0.0099 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KXX81529.1 - 0.019 14.0 0.0 0.044 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3176 PF11374.3 KXX81530.1 - 4.3e-11 42.6 0.6 8.4e-11 41.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DoxX PF07681.7 KXX81530.1 - 0.079 13.3 1.2 0.4 11.1 0.2 2.3 2 1 0 2 2 2 0 DoxX Amino_oxidase PF01593.19 KXX81533.1 - 3.7e-33 115.2 0.0 8.8e-33 114.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX81533.1 - 5.2e-12 45.6 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KXX81533.1 - 2e-07 30.2 0.3 1e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX81533.1 - 3.6e-06 27.2 0.4 5.2e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX81533.1 - 6.1e-05 23.1 0.0 0.00023 21.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX81533.1 - 0.00014 21.0 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KXX81533.1 - 0.00051 19.1 0.2 0.0011 18.0 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KXX81533.1 - 0.00073 18.1 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KXX81533.1 - 0.0025 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain EnY2 PF10163.4 KXX81533.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 Pyr_redox_2 PF07992.9 KXX81533.1 - 0.013 15.4 0.0 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KXX81533.1 - 0.013 15.1 0.1 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KXX81533.1 - 0.028 13.5 0.2 0.17 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX81533.1 - 0.12 12.2 1.4 0.71 9.6 0.0 2.5 3 0 0 3 3 2 0 FAD-NAD(P)-binding FMO-like PF00743.14 KXX81533.1 - 0.26 9.4 0.2 0.36 8.9 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Ank_2 PF12796.2 KXX81534.1 - 2.3e-20 72.7 0.0 3.6e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX81534.1 - 9.2e-11 41.9 0.0 3.2e-06 27.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX81534.1 - 5.8e-10 38.4 0.4 0.0015 18.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KXX81534.1 - 4.9e-08 32.9 0.0 0.014 15.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81534.1 - 9.3e-07 28.5 0.2 0.086 13.1 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat DUF1327 PF07041.6 KXX81534.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1327) DUF4404 PF14357.1 KXX81534.1 - 0.053 13.9 0.1 9 6.7 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Methyltransf_23 PF13489.1 KXX81535.1 - 3.8e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81535.1 - 1.2e-10 42.0 0.0 1.3e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81535.1 - 2.9e-10 40.4 0.0 7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81535.1 - 2.8e-09 37.3 0.0 1.8e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX81535.1 - 1.3e-06 28.6 0.0 3.8e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81535.1 - 1.6e-06 27.8 0.0 2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81535.1 - 4.9e-05 22.5 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX81535.1 - 0.00037 20.4 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX81535.1 - 0.0044 16.4 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KXX81535.1 - 0.0057 16.1 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KXX81535.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KXX81535.1 - 0.0083 15.1 0.0 0.079 11.9 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.7 KXX81535.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 KXX81535.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Pkinase PF00069.20 KXX81536.1 - 4.9e-07 29.1 0.0 1.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81536.1 - 1.5e-05 24.2 0.0 3.5e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Hrs_helical PF12210.3 KXX81536.1 - 0.017 15.3 0.2 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pox_ser-thr_kin PF05445.6 KXX81536.1 - 0.026 13.3 0.1 0.19 10.4 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KXX81536.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like p450 PF00067.17 KXX81538.1 - 3.2e-70 236.9 0.0 4.1e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.9 KXX81539.1 - 1.1e-23 84.1 0.0 1.4e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 KXX81541.1 - 9.1e-07 28.2 0.9 1.2e-05 24.6 0.1 2.0 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81541.1 - 0.015 14.4 0.1 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase MR_MLE_C PF13378.1 KXX81542.1 - 4.1e-19 68.6 0.2 2.7e-18 65.9 0.0 2.4 3 1 1 4 4 4 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KXX81542.1 - 2.2e-13 50.5 0.1 2.4e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KXX81542.1 - 0.00094 19.1 0.1 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KXX81542.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Rad10 PF03834.9 KXX81544.1 - 8.9e-30 102.1 0.0 1.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KXX81544.1 - 0.0028 17.8 0.0 0.0076 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Acetyltransf_7 PF13508.1 KXX81546.1 - 1.4e-09 38.0 0.0 3.4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 KXX81546.1 - 2.3e-08 33.7 7.8 5.1e-08 32.7 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 KXX81546.1 - 8.4e-08 32.1 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX81546.1 - 8.9e-08 32.2 0.0 8.9e-05 22.6 0.0 3.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX81546.1 - 0.00013 21.8 0.0 0.00048 19.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 KXX81546.1 - 0.00033 19.3 0.2 0.0005 18.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FR47 PF08445.5 KXX81546.1 - 0.0036 17.0 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KXX81546.1 - 0.022 14.6 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TctC PF03401.9 KXX81546.1 - 0.04 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Fungal_trans PF04082.13 KXX81547.1 - 5.1e-26 91.1 0.0 7.8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81547.1 - 0.69 9.8 5.2 1.4 8.8 3.0 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.15 KXX81549.1 - 3.1e-134 448.0 0.0 3.6e-134 447.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DEAD PF00270.24 KXX81550.1 - 1.4e-41 141.7 0.3 2.5e-41 140.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX81550.1 - 8.7e-22 76.7 0.0 1.7e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KXX81550.1 - 8.3e-06 25.7 0.2 2.5e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KXX81550.1 - 0.11 12.6 0.1 0.63 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 KXX81552.1 - 2.5e-14 52.7 0.0 3.5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region BTG PF07742.7 KXX81552.1 - 0.046 13.2 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 BTG family XOO_2897-deam PF14440.1 KXX81552.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DUF234 PF03008.9 KXX81553.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function HTH_Tnp_4 PF13613.1 KXX81553.1 - 0.14 11.7 0.4 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease RXT2_N PF08595.6 KXX81554.1 - 9.1e-42 142.3 0.1 9.1e-42 142.3 0.1 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal Glyco_hydro_81 PF03639.8 KXX81555.1 - 1.1e-202 674.8 0.0 1.3e-202 674.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 FGGY_C PF02782.11 KXX81556.1 - 2e-75 252.7 0.7 4.4e-75 251.6 0.5 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KXX81556.1 - 8.3e-65 218.5 0.0 1.1e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DnaJ PF00226.26 KXX81557.1 - 8e-23 79.9 1.8 8e-23 79.9 1.2 2.0 2 0 0 2 2 2 1 DnaJ domain DUF1635 PF07795.6 KXX81557.1 - 0.059 12.7 1.6 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Arc_PepC_II PF06847.6 KXX81557.1 - 0.21 12.0 0.7 0.85 10.0 0.0 2.3 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Stn1 PF10451.4 KXX81558.1 - 3e-15 55.7 0.7 2.3e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KXX81558.1 - 7e-05 22.6 0.4 0.00018 21.2 0.3 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain TOBE PF03459.12 KXX81558.1 - 0.14 12.2 0.4 0.27 11.3 0.3 1.4 1 0 0 1 1 1 0 TOBE domain NTP_transferase PF00483.18 KXX81559.1 - 1.8e-50 171.5 0.0 5.3e-50 170.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KXX81559.1 - 4.2e-16 57.6 11.0 1.1e-09 37.3 0.7 4.0 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KXX81559.1 - 5.3e-10 39.5 0.0 7.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KXX81559.1 - 6.3e-07 28.8 0.8 6.3e-07 28.8 0.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase dsrm PF00035.20 KXX81560.1 - 0.00012 22.5 0.0 0.00023 21.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KXX81560.1 - 0.00072 19.7 0.1 0.0017 18.6 0.0 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PXA PF02194.10 KXX81561.1 - 4.4e-55 186.1 0.2 4.4e-55 186.1 0.1 1.9 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KXX81561.1 - 3.2e-30 104.5 0.0 1.1e-29 102.7 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KXX81561.1 - 2.4e-20 72.3 0.3 6.8e-20 70.9 0.2 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KXX81561.1 - 1.3e-10 41.4 0.0 3.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRM_1 PF00076.17 KXX81562.1 - 2.5e-23 81.5 0.1 8.5e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX81562.1 - 4.2e-18 65.0 0.0 4.5e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX81562.1 - 1.8e-12 46.8 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX81562.1 - 0.061 13.1 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif HA2 PF04408.18 KXX81565.1 - 4.7e-21 74.7 0.0 6.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) GST_N_3 PF13417.1 KXX81566.1 - 6.8e-10 39.0 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KXX81566.1 - 5.7e-09 35.8 0.0 1.7e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX81566.1 - 8.3e-09 35.5 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX81566.1 - 8.7e-09 35.2 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX81566.1 - 2.3e-05 24.7 0.1 4.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX81566.1 - 6.1e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4078 PF13300.1 KXX81567.1 - 7.7e-30 102.8 18.7 7.7e-30 102.8 13.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) APG6 PF04111.7 KXX81567.1 - 1.4 7.9 6.5 2.1 7.3 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Homoserine_dh PF00742.14 KXX81568.1 - 3e-52 176.8 0.0 3.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KXX81568.1 - 6.4e-18 65.2 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.11 KXX81568.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_4 PF02390.12 KXX81569.1 - 3.6e-53 179.5 0.0 4.6e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KXX81569.1 - 6.8e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81569.1 - 0.00029 21.3 0.0 0.00046 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KXX81569.1 - 0.007 15.3 0.0 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_12 PF08242.7 KXX81569.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81569.1 - 0.017 14.6 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KXX81569.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 KXX81569.1 - 0.096 13.1 0.0 0.53 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Drf_GBD PF06371.8 KXX81570.1 - 2.4e-13 49.8 2.6 5.5e-12 45.4 1.8 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain adh_short PF00106.20 KXX81571.1 - 0.057 13.3 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Dimer_Tnp_hAT PF05699.9 KXX81571.1 - 0.089 12.4 0.1 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region MFS_1 PF07690.11 KXX81572.1 - 3.3e-21 75.4 41.0 3.3e-21 75.4 28.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KXX81573.1 - 2.4e-35 121.9 63.7 2.6e-35 121.7 42.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily SIR2 PF02146.12 KXX81574.1 - 3.6e-34 118.0 0.0 9.4e-34 116.6 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Glyco_hydro_16 PF00722.16 KXX81575.1 - 2.1e-42 144.4 0.1 2.1e-42 144.4 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.6 KXX81575.1 - 1.7 6.4 8.7 2.2 6.0 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen E1-E2_ATPase PF00122.15 KXX81576.1 - 3.8e-21 75.1 0.1 9e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KXX81576.1 - 1.5e-20 74.2 0.1 3.8e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX81576.1 - 6.6e-17 62.6 3.1 6.3e-16 59.4 2.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX81576.1 - 4.6e-12 45.7 0.0 1.6e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KXX81576.1 - 0.00072 19.1 0.6 0.0058 16.2 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KXX81576.1 - 0.029 14.5 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 KXX81577.1 - 0.0032 17.3 7.7 0.0067 16.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.16 KXX81578.1 - 1.9e-37 126.5 27.9 3.7e-09 35.9 0.3 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KXX81578.1 - 3e-23 82.3 0.0 3.7e-15 56.3 0.0 4.0 1 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KXX81578.1 - 0.00081 19.3 0.0 0.016 15.2 0.0 2.7 1 1 1 2 2 2 1 Prenyltransferase-like Acyltransferase PF01553.16 KXX81579.1 - 7.8e-10 38.3 0.0 8e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Sec2p PF06428.6 KXX81579.1 - 0.049 13.4 0.3 0.15 11.9 0.2 1.8 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-UBP PF02148.14 KXX81580.1 - 1.1e-16 60.7 9.1 3.3e-16 59.1 6.3 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 KXX81580.1 - 2.4e-16 59.2 0.0 4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 KXX81580.1 - 3e-09 36.5 9.7 3e-09 36.5 6.7 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX81580.1 - 0.00011 21.8 7.0 0.00011 21.8 4.8 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX81580.1 - 0.00018 21.0 8.0 0.00047 19.7 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX81580.1 - 0.0021 17.6 6.7 0.0021 17.6 4.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX81580.1 - 0.0039 17.1 8.6 0.0039 17.1 6.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX81580.1 - 0.0041 17.2 5.7 0.0041 17.2 4.0 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KXX81580.1 - 0.008 15.9 3.3 0.019 14.7 2.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Exonuc_VII_L PF02601.10 KXX81580.1 - 0.12 11.5 6.8 0.18 10.9 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-Apc11 PF12861.2 KXX81580.1 - 0.16 11.7 5.8 0.45 10.3 4.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KXX81580.1 - 1.1 9.0 9.9 0.062 13.0 1.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger CP12 PF02672.10 KXX81580.1 - 2.8 8.4 6.4 33 5.0 2.2 2.5 2 0 0 2 2 2 0 CP12 domain DUF904 PF06005.7 KXX81580.1 - 3.8 7.8 15.8 0.78 10.0 2.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KXX81580.1 - 4.7 7.0 13.8 0.2 11.5 3.7 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KXX81580.1 - 5.1 6.6 5.8 0.39 10.2 0.5 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 KXX81580.1 - 8.4 5.5 11.7 0.41 9.8 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Suc_Fer-like PF06999.7 KXX81581.1 - 5.7e-33 114.8 0.0 1.4e-28 100.5 0.0 2.1 2 0 0 2 2 2 2 Sucrase/ferredoxin-like FAM75 PF14650.1 KXX81581.1 - 2.9 7.1 5.1 4.3 6.6 3.5 1.2 1 0 0 1 1 1 0 FAM75 family UCR_hinge PF02320.11 KXX81582.1 - 5.1e-27 93.6 8.2 1.2e-26 92.4 5.7 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UBN_AB PF14075.1 KXX81582.1 - 0.12 12.0 5.0 0.15 11.7 3.5 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain APG6 PF04111.7 KXX81582.1 - 0.14 11.1 11.7 0.17 10.9 8.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CKAP2_C PF15297.1 KXX81582.1 - 0.21 10.3 14.1 0.24 10.1 9.8 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Tom37_C PF11801.3 KXX81582.1 - 0.35 10.7 6.2 0.55 10.0 4.3 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF572 PF04502.8 KXX81582.1 - 0.36 9.9 15.8 0.46 9.6 10.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.9 KXX81582.1 - 0.46 8.4 9.5 0.46 8.4 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 KXX81582.1 - 0.51 8.3 10.9 0.61 8.0 7.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tim54 PF11711.3 KXX81582.1 - 0.65 8.5 11.9 0.7 8.4 8.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EBV-NA3 PF05009.7 KXX81582.1 - 0.73 9.0 9.8 0.98 8.6 6.8 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Daxx PF03344.10 KXX81582.1 - 1.2 7.5 24.9 1.4 7.3 17.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2052 PF09747.4 KXX81582.1 - 1.4 8.8 17.7 2.1 8.2 12.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RRN3 PF05327.6 KXX81582.1 - 1.6 6.7 10.8 1.9 6.4 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 KXX81582.1 - 1.7 7.9 24.1 2.1 7.6 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 KXX81582.1 - 1.9 7.4 19.1 2 7.4 13.2 1.1 1 0 0 1 1 1 0 BUD22 Pet191_N PF10203.4 KXX81582.1 - 1.9 8.5 8.5 0.28 11.2 2.5 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF740 PF05340.7 KXX81582.1 - 2.3 6.5 14.7 2.8 6.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DDHD PF02862.12 KXX81582.1 - 2.7 7.7 8.3 3.1 7.5 5.8 1.3 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.7 KXX81582.1 - 3.2 6.4 7.7 3.7 6.1 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.6 KXX81582.1 - 3.8 7.3 25.0 6 6.7 17.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mitofilin PF09731.4 KXX81582.1 - 4.4 5.8 18.8 5.4 5.5 13.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4045 PF13254.1 KXX81582.1 - 4.5 6.4 12.1 5.2 6.2 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Spore_coat_CotO PF14153.1 KXX81582.1 - 5 6.5 20.7 6.4 6.1 14.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 KXX81582.1 - 5.3 5.5 10.3 5.8 5.4 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pilt PF15453.1 KXX81582.1 - 6.8 6.2 13.6 8.1 6.0 9.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Asp-B-Hydro_N PF05279.6 KXX81582.1 - 7.7 6.2 23.8 10 5.9 16.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDRGK PF09756.4 KXX81582.1 - 7.9 5.8 20.1 12 5.2 14.0 1.3 1 0 0 1 1 1 0 DDRGK domain Ycf1 PF05758.7 KXX81582.1 - 8.4 3.9 13.1 9.2 3.8 9.1 1.0 1 0 0 1 1 1 0 Ycf1 WWbp PF10349.4 KXX81583.1 - 5.3e-13 49.8 4.6 9.8e-13 49.0 3.2 1.4 1 0 0 1 1 1 1 WW-domain ligand protein DHDPS PF00701.17 KXX81584.1 - 2.6e-41 141.1 0.0 3.4e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 KXX81584.1 - 0.089 12.9 0.1 1 9.5 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix Methyltransf_33 PF10017.4 KXX81585.1 - 8.4e-28 96.8 0.0 2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KXX81585.1 - 2.1e-19 69.8 2.9 7e-12 45.2 0.3 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KXX81585.1 - 2.9e-08 34.1 0.9 7.1e-08 32.8 0.6 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KXX81585.1 - 0.00044 20.5 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain IF-2B PF01008.12 KXX81586.1 - 1.1e-34 119.7 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family 4_1_CTD PF05902.8 KXX81586.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) adh_short PF00106.20 KXX81587.1 - 1.7e-27 96.3 0.7 2.3e-27 95.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81587.1 - 5.5e-21 75.4 0.5 2.9e-20 73.0 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX81587.1 - 7.9e-11 41.9 0.6 1.9e-10 40.7 0.4 1.6 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 KXX81587.1 - 0.0013 18.6 0.3 0.0025 17.6 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 KXX81587.1 - 0.0018 17.9 1.0 0.0031 17.1 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KXX81587.1 - 0.088 11.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.11 KXX81588.1 - 1.2e-27 96.5 29.2 1.2e-27 96.5 20.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX81588.1 - 0.00029 19.5 13.4 0.00029 19.5 9.3 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter CFEM PF05730.6 KXX81589.1 - 2.2e-12 46.6 11.6 2.2e-12 46.6 8.0 1.6 2 0 0 2 2 2 1 CFEM domain p450 PF00067.17 KXX81590.1 - 1.6e-43 148.9 0.0 2.5e-36 125.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2217 PF10265.4 KXX81590.1 - 0.089 11.5 0.1 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Methyltransf_2 PF00891.13 KXX81592.1 - 1.8e-19 69.9 0.0 2.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KXX81592.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KXX81592.1 - 0.0015 18.3 0.1 0.0056 16.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain HTH_5 PF01022.15 KXX81592.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family ADH_N PF08240.7 KXX81593.1 - 4.1e-27 94.0 1.9 6.8e-27 93.3 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KXX81593.1 - 3.9e-09 35.9 0.4 3.9e-09 35.9 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KXX81593.1 - 9.7e-06 25.1 0.1 0.0019 17.7 0.0 2.7 2 1 0 2 2 2 2 Zinc-binding dehydrogenase adh_short PF00106.20 KXX81595.1 - 6.8e-23 81.4 0.1 1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81595.1 - 4.7e-15 56.0 0.0 7.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX81595.1 - 1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX81595.1 - 2.3e-06 27.7 0.0 5.8e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX81595.1 - 3.8e-06 26.5 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX81595.1 - 0.002 17.8 0.2 0.0055 16.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KXX81595.1 - 0.004 16.0 0.1 0.011 14.6 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain DUF2292 PF10055.4 KXX81595.1 - 0.28 10.5 1.3 0.4 10.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Rft-1 PF04506.8 KXX81596.1 - 3.4e-94 316.2 2.3 4.3e-94 315.8 1.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 KXX81596.1 - 1.6e-06 27.5 12.6 1.6e-06 27.5 8.7 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DEAD PF00270.24 KXX81597.1 - 8.8e-48 161.9 0.0 7.2e-45 152.4 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX81597.1 - 6.3e-30 102.8 0.0 6.8e-29 99.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KXX81597.1 - 0.011 14.1 1.3 0.016 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 KXX81597.1 - 0.12 11.4 0.0 0.12 11.4 0.0 3.3 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit MARVEL PF01284.18 KXX81598.1 - 0.0023 17.7 22.7 0.0033 17.2 15.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Ycf9 PF01737.12 KXX81598.1 - 2.4 7.6 10.7 0.6 9.5 0.9 2.6 2 1 0 2 2 2 0 YCF9 Elong-fact-P_C PF09285.6 KXX81600.1 - 0.12 11.7 0.7 0.27 10.6 0.5 1.6 1 0 0 1 1 1 0 Elongation factor P, C-terminal Glycos_transf_2 PF00535.21 KXX81601.1 - 5.2e-36 123.8 0.0 6.2e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KXX81601.1 - 3.8e-14 53.0 0.0 7.2e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KXX81601.1 - 1.8e-09 37.0 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KXX81601.1 - 3.5e-06 26.4 0.0 5.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KXX81601.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 E1-E2_ATPase PF00122.15 KXX81602.1 - 5.8e-58 195.6 3.6 1e-57 194.8 2.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KXX81602.1 - 7.9e-34 116.7 1.4 7.9e-34 116.7 1.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KXX81602.1 - 9e-28 98.1 0.3 8.9e-23 81.8 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX81602.1 - 6e-22 77.4 0.0 1.7e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KXX81602.1 - 1.4e-12 46.8 0.0 3.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KXX81602.1 - 1.5e-11 44.7 0.0 4e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX81602.1 - 4e-07 29.8 0.4 1.3e-05 24.8 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KXX81604.1 - 9.5e-52 175.7 0.0 1.3e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81604.1 - 4.5e-22 78.3 0.0 9.9e-22 77.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KXX81604.1 - 0.054 12.2 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KXX81604.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FAD_binding_3 PF01494.14 KXX81605.1 - 1.1e-80 271.3 0.0 1.5e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX81605.1 - 0.001 19.0 0.1 0.0022 17.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX81605.1 - 0.0017 17.3 0.7 0.0077 15.1 0.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX81605.1 - 0.016 15.2 1.8 0.036 14.1 1.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX81605.1 - 0.022 13.6 0.8 0.041 12.7 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KXX81605.1 - 0.036 13.1 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KXX81605.1 - 0.051 12.5 0.2 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KXX81605.1 - 0.076 13.4 0.0 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX81605.1 - 0.12 12.4 0.1 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF221 PF02714.10 KXX81606.1 - 2.5e-94 315.7 17.9 4e-94 315.1 12.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KXX81606.1 - 4.5e-39 133.5 2.7 4.5e-39 133.5 1.8 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KXX81606.1 - 2.7e-15 56.6 0.2 5.3e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF1192 PF06698.6 KXX81606.1 - 0.4 10.5 0.5 0.77 9.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PfkB PF00294.19 KXX81607.1 - 3e-50 171.0 3.5 2.6e-42 145.0 1.1 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase eIF3_subunit PF08597.5 KXX81608.1 - 2.8e-66 223.5 25.3 3e-66 223.4 17.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FNIP_N PF14636.1 KXX81608.1 - 1.6 9.2 8.0 0.74 10.2 3.2 2.0 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Spore_coat_CotO PF14153.1 KXX81608.1 - 1.6 8.1 16.3 0.1 12.0 6.6 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Vpu PF00558.14 KXX81608.1 - 2.4 7.7 8.1 6.8 6.3 5.6 1.8 1 0 0 1 1 1 0 Vpu protein Nop53 PF07767.6 KXX81608.1 - 5.5 5.8 32.4 2.9 6.7 16.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 KXX81608.1 - 8.1 4.3 14.0 15 3.4 9.7 1.6 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KXX81609.1 - 0.0035 16.6 2.5 0.0057 15.9 1.7 1.2 1 0 0 1 1 1 1 NOA36 protein zf-C2H2_4 PF13894.1 KXX81609.1 - 0.35 11.3 17.9 0.083 13.2 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX81609.1 - 2.9 8.3 10.1 0.68 10.3 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain MDM31_MDM32 PF08118.6 KXX81610.1 - 3e-187 623.0 1.2 5.5e-186 618.9 0.8 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 KXX81610.1 - 0.0031 16.9 0.3 0.0031 16.9 0.2 1.6 2 0 0 2 2 2 1 TraH_2 Peptidase_M61 PF05299.7 KXX81610.1 - 0.12 12.4 1.3 3.5 7.6 0.2 3.1 3 0 0 3 3 3 0 M61 glycyl aminopeptidase KH_1 PF00013.24 KXX81611.1 - 7.8e-05 22.2 1.7 0.00018 21.1 0.9 1.8 2 0 0 2 2 2 1 KH domain adh_short PF00106.20 KXX81612.1 - 1.8e-21 76.7 2.5 2.5e-21 76.3 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81612.1 - 1.4e-17 64.3 1.1 2.3e-17 63.5 0.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX81612.1 - 2.6e-09 37.0 3.4 1e-08 35.0 2.4 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX81612.1 - 8.7e-05 22.0 0.5 0.00038 19.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX81612.1 - 0.003 16.5 0.1 0.0041 16.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KXX81612.1 - 0.014 15.8 0.5 0.026 14.9 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KXX81612.1 - 0.041 13.8 3.3 0.88 9.5 2.3 2.2 1 1 0 1 1 1 0 NADH(P)-binding PDZ PF00595.19 KXX81612.1 - 0.046 13.8 0.1 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Phage_Coat_Gp8 PF05371.7 KXX81612.1 - 0.14 11.7 1.5 4.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Rad60-SLD PF11976.3 KXX81613.1 - 8e-15 54.2 0.3 1.1e-13 50.7 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GFA PF04828.9 KXX81614.1 - 3.4e-14 52.5 9.0 8.1e-10 38.5 0.2 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KXX81614.1 - 0.043 13.6 1.3 0.1 12.4 0.0 2.4 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_CWC PF14375.1 KXX81614.1 - 0.22 11.4 10.9 0.89 9.5 0.8 2.8 3 0 0 3 3 3 0 Cysteine-rich CWC BCDHK_Adom3 PF10436.4 KXX81615.1 - 5.8e-45 152.7 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KXX81615.1 - 1.1e-16 60.5 0.0 1.2e-15 57.2 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF663 PF04950.7 KXX81616.1 - 3.6e-89 298.6 0.0 3.6e-89 298.6 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KXX81616.1 - 1.4e-27 95.0 0.0 4.9e-26 90.0 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KXX81616.1 - 6.4e-06 25.7 0.0 0.0012 18.3 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KXX81616.1 - 1.2e-05 25.4 0.0 3.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX81616.1 - 1.2e-05 25.3 0.0 3.7e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 KXX81616.1 - 0.00032 21.1 0.4 0.0011 19.4 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein ABC_tran PF00005.22 KXX81616.1 - 0.00038 20.7 1.1 0.0033 17.7 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 KXX81616.1 - 0.00038 20.6 0.0 0.00099 19.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KXX81616.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 KXX81616.1 - 0.00063 19.6 0.0 0.0019 18.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KXX81616.1 - 0.0011 18.6 0.1 0.0035 17.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KXX81616.1 - 0.0014 18.5 0.7 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX81616.1 - 0.0015 17.9 0.0 0.0048 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KXX81616.1 - 0.0018 17.7 0.0 0.006 16.0 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KXX81616.1 - 0.0018 19.0 0.0 0.0018 19.0 0.0 4.3 3 1 1 4 4 2 1 AAA domain MobB PF03205.9 KXX81616.1 - 0.0023 17.6 0.0 0.0072 16.0 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KXX81616.1 - 0.0036 17.1 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KXX81616.1 - 0.005 16.3 1.9 2.6 7.4 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 KXX81616.1 - 0.0056 16.9 0.0 0.0056 16.9 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 KXX81616.1 - 0.0067 15.9 0.1 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_5 PF07728.9 KXX81616.1 - 0.0086 15.7 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KXX81616.1 - 0.0094 14.8 2.3 0.031 13.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 KXX81616.1 - 0.01 15.4 0.1 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KXX81616.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KXX81616.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KXX81616.1 - 0.019 14.1 0.0 0.065 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KXX81616.1 - 0.032 13.9 0.2 0.032 13.9 0.1 1.9 2 0 0 2 2 1 0 NTPase DUF3435 PF11917.3 KXX81616.1 - 0.26 9.9 9.5 0.55 8.8 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) AAA_23 PF13476.1 KXX81616.1 - 1.2 9.3 0.0 1.2 9.3 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.1 KXX81616.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.7 3 1 0 4 4 3 0 AAA domain Radical_SAM PF04055.16 KXX81617.1 - 3.6e-06 27.2 0.0 7.4e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KXX81617.1 - 0.00024 21.2 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KXX81617.1 - 0.015 15.3 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Kazal_2 PF07648.10 KXX81617.1 - 0.016 15.1 0.9 0.038 13.9 0.6 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain DUF1681 PF07933.9 KXX81618.1 - 1.7e-52 177.2 0.0 2.2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SH3_2 PF07653.12 KXX81618.1 - 0.03 13.7 0.1 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 KXX81618.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Ank_2 PF12796.2 KXX81619.1 - 4.3e-114 373.1 12.0 4.6e-13 49.3 0.1 20.1 8 4 10 19 19 18 16 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX81619.1 - 2.1e-94 308.3 30.1 6.9e-07 29.6 0.0 25.0 15 6 10 25 25 25 19 Ankyrin repeats (many copies) Ank PF00023.25 KXX81619.1 - 3.2e-75 244.4 52.3 4.2e-06 26.2 0.1 30.0 30 4 0 30 30 29 15 Ankyrin repeat Ank_3 PF13606.1 KXX81619.1 - 1.2e-62 201.5 25.7 0.00013 21.8 0.0 28.9 29 2 1 30 30 29 13 Ankyrin repeat Ank_5 PF13857.1 KXX81619.1 - 4.1e-62 204.8 59.4 3.8e-06 26.9 0.7 23.8 19 6 5 24 24 23 15 Ankyrin repeats (many copies) NACHT PF05729.7 KXX81619.1 - 2.3e-12 46.8 0.0 7.7e-10 38.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX81619.1 - 4.3e-05 23.5 0.0 0.00018 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KXX81619.1 - 0.0024 17.2 0.0 0.11 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KXX81619.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KXX81619.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 KXX81619.1 - 0.034 14.9 0.0 0.11 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KXX81619.1 - 0.087 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KXX81619.1 - 0.11 12.7 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.1 KXX81619.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 KXX81619.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 KXX81619.1 - 0.23 11.6 0.0 0.54 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KXX81619.1 - 0.45 9.4 0.0 0.73 8.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GvpD PF07088.6 KXX81619.1 - 0.48 8.6 0.0 0.77 8.0 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein Chitin_synth_2 PF03142.10 KXX81620.1 - 7.4e-257 852.9 1.1 9.9e-257 852.5 0.8 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KXX81620.1 - 4.9e-166 553.6 0.0 6.4e-166 553.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KXX81620.1 - 1.5e-18 66.2 0.1 9.9e-18 63.6 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KXX81620.1 - 2.1e-16 60.4 0.2 1.4e-12 47.8 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KXX81620.1 - 1.3e-15 56.8 0.0 9.7e-10 38.1 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KXX81620.1 - 3e-13 49.9 7.7 3e-13 49.9 5.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KXX81620.1 - 3.7e-05 23.4 0.0 0.006 16.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 KXX81620.1 - 0.00025 21.0 0.3 0.00091 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Glyco_transf_21 PF13506.1 KXX81620.1 - 0.003 16.8 0.1 0.0097 15.2 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 TrwB_AAD_bind PF10412.4 KXX81620.1 - 0.008 14.8 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 KXX81620.1 - 0.016 15.3 0.3 0.074 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KXX81620.1 - 0.08 12.3 0.2 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 KXX81620.1 - 0.09 11.8 0.1 0.24 10.4 0.1 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KXX81620.1 - 0.21 10.2 0.0 0.49 9.0 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 KXX81620.1 - 0.28 10.3 0.3 1.2 8.2 0.3 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2592 PF10766.4 KXX81620.1 - 0.35 10.2 2.3 0.97 8.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 KXX81621.1 - 1.8e-230 765.8 0.0 2.4e-230 765.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KXX81621.1 - 5.4e-60 203.2 0.0 9.9e-51 172.6 0.0 2.6 2 1 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 KXX81621.1 - 4.6e-19 68.0 0.0 2.9e-11 42.9 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KXX81621.1 - 5.3e-17 62.1 3.9 5.3e-17 62.1 2.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KXX81621.1 - 4.9e-15 55.0 2.0 8.8e-14 51.0 1.8 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KXX81621.1 - 9.9e-15 54.9 0.0 8.6e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KXX81621.1 - 1.5e-06 27.6 0.0 4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KXX81621.1 - 0.00067 19.3 0.0 0.05 13.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.20 KXX81622.1 - 0.00013 21.2 0.0 0.00041 19.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain A_deaminase_N PF08451.6 KXX81622.1 - 0.027 14.4 0.4 0.61 10.1 0.1 2.4 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal APH PF01636.18 KXX81622.1 - 0.078 12.6 0.8 0.3 10.7 0.7 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Aldolase_II PF00596.16 KXX81623.1 - 1.2e-21 77.1 0.3 1.9e-21 76.5 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ala_racemase_N PF01168.15 KXX81625.1 - 1.1e-40 139.4 0.0 1.4e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain F-box-like PF12937.2 KXX81626.1 - 4.5e-08 32.6 0.3 1e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX81626.1 - 0.021 14.4 0.5 0.021 14.4 0.3 2.8 2 1 0 2 2 2 0 F-box domain DJ-1_PfpI_N PF13587.1 KXX81627.1 - 0.037 13.5 1.1 1.6 8.2 0.0 2.6 3 0 0 3 3 3 0 N-terminal domain of DJ-1_PfpI family tRNA-synt_1 PF00133.17 KXX81628.1 - 1.1e-221 737.0 0.0 1.8e-221 736.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KXX81628.1 - 2e-27 95.8 0.0 8e-27 93.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KXX81628.1 - 5.4e-20 71.4 0.3 1.2e-08 34.0 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KXX81628.1 - 0.021 13.9 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain BLOC1_2 PF10046.4 KXX81629.1 - 0.27 11.3 0.3 0.82 9.8 0.1 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KOW PF00467.24 KXX81630.1 - 1.5e-06 27.7 1.4 4.3e-06 26.2 1.0 1.8 1 0 0 1 1 1 1 KOW motif Sfi1 PF08457.5 KXX81631.1 - 2.1e-128 429.2 80.2 1.2e-124 416.8 51.1 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Cupin_8 PF13621.1 KXX81631.1 - 0.012 15.1 0.4 0.012 15.1 0.3 1.9 2 0 0 2 2 2 0 Cupin-like domain Mo25 PF08569.6 KXX81633.1 - 1.3e-126 422.1 0.0 1.5e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Mo25-like GspL_C PF12693.2 KXX81633.1 - 0.059 13.1 0.3 0.098 12.4 0.2 1.2 1 0 0 1 1 1 0 GspL periplasmic domain Hpt PF01627.18 KXX81633.1 - 0.11 12.5 0.2 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Hpt domain Mito_carr PF00153.22 KXX81634.1 - 3.8e-29 100.2 0.3 6.3e-14 51.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_6 PF13516.1 KXX81635.1 - 0.005 16.7 0.8 14 6.1 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 KXX81635.1 - 0.024 14.6 2.8 13 6.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 KXX81635.1 - 0.028 14.0 7.8 9 6.0 0.4 5.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KXX81635.1 - 2.6 8.6 4.3 3.1e+02 2.3 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.20 KXX81636.1 - 3e-70 236.3 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81636.1 - 6.6e-36 123.6 0.0 9.8e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX81636.1 - 3.6e-05 22.8 0.4 0.0022 16.9 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KXX81636.1 - 0.00043 19.4 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX81636.1 - 0.0015 18.3 0.1 0.0087 15.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KXX81636.1 - 0.19 10.4 0.1 2.3 6.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RHD3 PF05879.7 KXX81637.1 - 0 1080.2 0.0 0 1079.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KXX81637.1 - 3.7e-07 29.4 0.0 6.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KXX81637.1 - 9.9e-07 28.7 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KXX81637.1 - 0.00011 22.0 0.0 0.00032 20.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KXX81637.1 - 0.00068 19.6 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KXX81637.1 - 0.00092 19.7 0.1 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KXX81637.1 - 0.06 12.3 0.1 0.14 11.1 0.1 1.6 2 0 0 2 2 2 0 Septin Amidohydro_1 PF01979.15 KXX81638.1 - 9.6e-38 130.6 0.0 1.2e-37 130.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KXX81638.1 - 2.2e-09 37.0 0.6 4.6e-06 26.1 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KXX81638.1 - 1.5e-07 31.7 0.1 0.0021 18.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KXX81638.1 - 3e-05 23.7 0.0 7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KXX81638.1 - 0.0004 19.4 0.0 0.0016 17.4 0.0 1.9 2 1 0 2 2 2 1 Adenosine/AMP deaminase Dpy-30 PF05186.8 KXX81638.1 - 0.064 12.7 0.1 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif Fructosamin_kin PF03881.9 KXX81639.1 - 8.7e-63 211.9 0.0 1.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KXX81639.1 - 0.0037 17.0 0.0 0.0057 16.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2 PF00096.21 KXX81640.1 - 0.00013 22.1 8.3 0.034 14.4 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX81640.1 - 0.00062 19.9 9.1 0.16 12.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Docking PF08990.6 KXX81640.1 - 0.11 11.7 1.6 0.21 10.8 1.1 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking zf-C2H2_jaz PF12171.3 KXX81640.1 - 0.83 9.8 2.8 3.1 8.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Hexapep PF00132.19 KXX81641.1 - 1.3e-07 30.8 2.2 0.0054 16.1 0.1 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KXX81641.1 - 2.3e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KXX81641.1 - 0.00037 19.8 0.0 0.00079 18.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KXX81641.1 - 0.12 12.0 8.0 0.24 11.0 1.7 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KXX81641.1 - 0.17 10.4 0.4 0.34 9.4 0.3 1.4 1 0 0 1 1 1 0 L-fucokinase DUF2457 PF10446.4 KXX81641.1 - 4.4 5.9 24.1 6 5.4 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2945 PF11160.3 KXX81642.1 - 1.3e-15 56.9 0.3 1.5e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Glyco_hydro_61 PF03443.9 KXX81643.1 - 3.9e-51 173.9 0.7 4.6e-51 173.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KXX81643.1 - 0.016 15.2 0.1 0.053 13.5 0.1 1.8 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.9 KXX81644.1 - 3.1e-48 164.4 0.1 4.6e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med18 PF09637.5 KXX81645.1 - 2.9e-17 63.0 0.1 3.3e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Med18 protein adh_short PF00106.20 KXX81646.1 - 1.3e-15 57.7 0.2 1.9e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX81646.1 - 1.7e-08 34.3 0.4 5.5e-08 32.6 0.1 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX81646.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KXX81646.1 - 8.5e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MS_channel PF00924.13 KXX81647.1 - 4.8e-21 75.0 2.6 9.3e-21 74.1 1.8 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 KXX81647.1 - 0.0017 18.4 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KXX81647.1 - 0.0032 16.7 0.0 0.0067 15.7 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KXX81647.1 - 0.0035 16.5 0.1 0.0094 15.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KXX81647.1 - 0.0072 16.1 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain ODV-E18 PF10717.4 KXX81647.1 - 0.19 11.2 1.6 0.56 9.6 0.5 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Vma12 PF11712.3 KXX81647.1 - 1.9 8.2 8.9 4.6 6.9 1.5 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DLH PF01738.13 KXX81648.1 - 1.2e-28 99.9 0.0 1.5e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX81648.1 - 3.6e-06 26.7 0.1 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KXX81648.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KXX81648.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KXX81648.1 - 0.12 10.7 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Radical_SAM PF04055.16 KXX81649.1 - 0.03 14.4 1.5 1.1 9.4 0.1 3.8 3 0 0 3 3 3 0 Radical SAM superfamily Dynein_light PF01221.13 KXX81649.1 - 0.058 13.3 0.3 52 3.9 0.0 4.7 4 0 0 4 4 4 0 Dynein light chain type 1 DASH_Dam1 PF08653.5 KXX81649.1 - 0.18 11.5 2.7 22 4.9 0.0 5.7 5 0 0 5 5 5 0 DASH complex subunit Dam1 tRNA-synt_2b PF00587.20 KXX81650.1 - 5.7e-23 81.3 0.0 8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KXX81650.1 - 1.2e-12 47.7 1.3 4.6e-12 45.9 0.9 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RNA12 PF10443.4 KXX81651.1 - 9.6e-163 541.6 0.9 1.2e-162 541.3 0.6 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 KXX81651.1 - 2.6e-06 26.9 0.0 1.1e-05 24.9 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX81651.1 - 0.00044 20.0 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 KXX81651.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) RRM_6 PF14259.1 KXX81651.1 - 0.082 12.9 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.3 KXX81652.1 - 3.3e-11 42.4 0.1 3.3e-11 42.4 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81652.1 - 3.8e-06 26.6 15.2 7.8e-06 25.7 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.15 KXX81653.1 - 1.8e-259 861.7 3.0 2.1e-259 861.5 2.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX81653.1 - 5.2e-17 61.4 0.0 8.5e-16 57.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KXX81653.1 - 0.0032 17.1 0.0 0.0078 15.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KXX81653.1 - 0.0051 15.9 0.1 0.019 14.1 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KXX81653.1 - 0.03 14.1 3.0 1.5 8.7 0.1 3.1 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.6 KXX81653.1 - 0.044 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 StbA protein DUF4404 PF14357.1 KXX81653.1 - 1.9 8.9 4.5 2.4 8.6 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3128 PF11326.3 KXX81654.1 - 4.1e-28 97.3 1.2 7.1e-28 96.5 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SLS PF14611.1 KXX81654.1 - 0.073 12.4 0.7 0.1 11.9 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TFIIA PF03153.8 KXX81654.1 - 0.31 10.8 2.6 0.32 10.8 1.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 KXX81654.1 - 5.5 6.2 26.9 8.3 5.6 18.7 1.2 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpc82 PF05645.8 KXX81655.1 - 3.8e-61 206.8 0.0 7.8e-61 205.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KXX81655.1 - 2.4e-19 68.9 0.7 5.3e-16 58.2 0.0 3.8 3 1 1 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KXX81655.1 - 0.0005 19.5 0.2 1.1 8.7 0.0 4.2 4 1 0 4 4 4 2 TFIIE alpha subunit ATP-synt_Eps PF04627.8 KXX81656.1 - 3e-21 74.7 2.9 3e-21 74.7 2.0 2.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 KXX81656.1 - 5.9e-17 61.8 0.0 9.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KXX81656.1 - 1.4e-14 54.2 0.0 6.6e-14 52.0 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Mak10 PF04112.8 KXX81657.1 - 3.1e-49 166.4 0.0 5e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.22 KXX81658.1 - 5.9e-55 182.9 1.1 5.2e-18 64.5 0.4 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KXX81658.1 - 0.013 15.3 0.2 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 UcrQ family Abp2 PF09441.5 KXX81659.1 - 8.8e-92 305.8 0.0 1.4e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 FlxA PF14282.1 KXX81661.1 - 0.12 12.2 4.2 0.28 11.1 2.9 1.5 1 0 0 1 1 1 0 FlxA-like protein Actin PF00022.14 KXX81662.1 - 7.1e-13 47.7 0.0 5.8e-12 44.7 0.0 2.4 2 1 0 2 2 2 1 Actin DUF834 PF05754.9 KXX81662.1 - 0.16 11.7 3.3 0.26 11.1 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF834) XPG_I PF00867.13 KXX81663.1 - 4.7e-24 84.2 0.0 9.2e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KXX81663.1 - 8.1e-08 32.4 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain SWIB PF02201.13 KXX81664.1 - 2.1e-13 49.7 0.0 4.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Rubrerythrin PF02915.12 KXX81664.1 - 0.035 14.4 0.6 0.088 13.1 0.4 1.7 1 0 0 1 1 1 0 Rubrerythrin RNase_HII PF01351.13 KXX81666.1 - 4.4e-44 150.4 0.0 2.3e-41 141.6 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease HII HET PF06985.6 KXX81668.1 - 2.6e-19 69.7 0.1 4.9e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NMD3 PF04981.8 KXX81668.1 - 0.036 13.1 0.8 7.1 5.6 0.1 2.4 2 0 0 2 2 2 0 NMD3 family Mif2_N PF15624.1 KXX81669.1 - 3.2e-38 131.3 0.5 3.2e-38 131.3 0.4 4.1 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 KXX81669.1 - 1.8e-33 114.3 0.4 2.8e-33 113.7 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KXX81669.1 - 4.2e-05 22.9 0.0 0.00014 21.2 0.0 2.0 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KXX81669.1 - 0.013 15.0 0.0 0.13 11.8 0.0 2.6 2 0 0 2 2 2 0 Cupin PAT1 PF09770.4 KXX81669.1 - 7 4.7 24.2 9.5 4.3 16.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Clr5 PF14420.1 KXX81671.1 - 2e-15 56.3 3.3 5.1e-15 55.1 2.3 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 KXX81671.1 - 3e-10 39.8 0.0 0.00058 19.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KXX81671.1 - 7.8e-05 22.4 0.0 0.68 9.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81671.1 - 0.011 16.2 0.1 16 6.4 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX81671.1 - 0.036 13.8 0.1 9 6.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 KXX81671.1 - 0.094 12.0 0.0 15 4.9 0.0 2.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 RNase_T PF00929.19 KXX81674.1 - 2.4e-26 92.9 0.0 2.7e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease GFO_IDH_MocA PF01408.17 KXX81675.1 - 4.7e-13 49.7 0.0 1.3e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KXX81675.1 - 2.6e-05 23.9 0.0 6.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 KXX81677.1 - 6.2e-33 113.1 0.0 9e-33 112.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KXX81677.1 - 4.5e-25 87.8 0.0 1e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KXX81677.1 - 3.9e-15 56.0 0.1 8.9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KXX81677.1 - 1.4e-08 34.5 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATG11 PF10377.4 KXX81678.1 - 7.5e-42 142.2 0.1 3.1e-41 140.2 0.1 2.2 1 0 0 1 1 1 1 Autophagy-related protein 11 Tropomyosin PF00261.15 KXX81678.1 - 0.00021 20.4 6.6 0.00021 20.4 4.6 7.9 5 2 3 8 8 8 1 Tropomyosin Fib_alpha PF08702.5 KXX81678.1 - 0.0066 16.5 8.7 0.0066 16.5 6.0 5.9 5 1 2 7 7 7 1 Fibrinogen alpha/beta chain family ELF PF03317.8 KXX81678.1 - 0.066 12.4 1.2 0.14 11.3 0.8 1.5 1 0 0 1 1 1 0 ELF protein Cleaved_Adhesin PF07675.6 KXX81678.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Cleaved Adhesin Domain HMG_box PF00505.14 KXX81679.1 - 1.3e-25 89.3 1.1 1.9e-25 88.9 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX81679.1 - 4e-19 68.7 1.8 5.6e-19 68.2 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KXX81679.1 - 0.0011 18.7 0.6 0.002 17.8 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KXX81679.1 - 0.022 14.9 0.1 0.068 13.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 KXX81679.1 - 0.11 12.7 2.3 0.22 11.7 0.2 2.0 1 1 1 2 2 2 0 Cold shock protein DEAD box A AATase PF07247.7 KXX81680.1 - 1.4e-17 63.3 0.0 2.7e-17 62.5 0.0 1.3 2 0 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.15 KXX81680.1 - 0.032 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Condensation domain WES_acyltransf PF03007.11 KXX81680.1 - 0.07 12.6 0.1 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribosomal_L9_N PF01281.14 KXX81681.1 - 2.7e-08 32.8 0.0 5.2e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 KXX81681.1 - 0.0036 17.3 0.1 0.46 10.6 0.0 3.0 2 1 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Cyclin_N PF00134.18 KXX81682.1 - 7.4e-44 148.3 0.1 1.9e-43 147.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KXX81682.1 - 4.3e-33 113.7 0.1 7.9e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 KXX81683.1 - 1.9e-46 157.0 2.2 9.9e-46 154.7 1.5 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KXX81683.1 - 2.2e-28 98.0 0.2 4.3e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PHD PF00628.24 KXX81686.1 - 6.3e-09 35.3 9.0 1.4e-08 34.2 6.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KXX81686.1 - 0.03 13.6 4.6 0.067 12.5 3.2 1.6 1 0 0 1 1 1 0 PHD-finger PLRV_ORF5 PF01690.12 KXX81686.1 - 8.4 5.4 23.1 0.047 12.8 9.3 2.1 3 0 0 3 3 3 0 Potato leaf roll virus readthrough protein Ion_trans PF00520.26 KXX81687.1 - 8.6e-108 358.1 74.3 2.6e-36 124.7 2.6 5.2 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.27 KXX81687.1 - 0.053 12.8 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 EF hand MMgT PF10270.4 KXX81688.1 - 1.7e-34 118.3 0.0 2e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter Endomucin PF07010.7 KXX81688.1 - 0.077 12.3 0.2 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Endomucin HMG_box PF00505.14 KXX81689.1 - 8.9e-11 41.9 2.4 2.2e-10 40.6 1.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX81689.1 - 0.0036 17.6 1.1 0.01 16.2 0.8 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 KXX81689.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.8 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 CFEM PF05730.6 KXX81690.1 - 0.0014 18.4 3.9 0.0024 17.6 2.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 KXX81690.1 - 1.8 7.9 11.8 2.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Vta1 like MutS_V PF00488.16 KXX81691.1 - 1.8e-42 145.3 0.0 1.2e-40 139.3 0.0 2.4 1 1 0 1 1 1 1 MutS domain V AAA_14 PF13173.1 KXX81691.1 - 0.0098 15.7 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain MutS_III PF05192.13 KXX81691.1 - 0.012 15.3 0.1 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 MutS domain III DAP3 PF10236.4 KXX81691.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 LSM PF01423.17 KXX81694.1 - 3.1e-17 61.8 0.1 4.1e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KXX81694.1 - 0.006 16.4 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HSP20 PF00011.16 KXX81695.1 - 1.6e-17 63.2 0.0 1.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family YTH PF04146.10 KXX81696.1 - 2.1e-56 189.3 0.0 3.1e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 KXX81696.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX81696.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX81696.1 - 0.18 11.6 0.1 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 KXX81697.1 - 2.9e-30 104.9 0.2 5.6e-30 104.0 0.2 1.6 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 KXX81698.1 - 9.7e-40 136.4 0.0 3.8e-39 134.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KXX81698.1 - 5e-23 81.2 0.0 1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sad1_UNC PF07738.8 KXX81698.1 - 0.083 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Cation_efflux PF01545.16 KXX81699.1 - 8.1e-31 107.1 12.6 9.9e-31 106.8 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family DMRL_synthase PF00885.14 KXX81701.1 - 4.8e-46 156.0 0.0 7.7e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Fungal_trans PF04082.13 KXX81702.1 - 3.1e-20 72.1 0.1 7.5e-20 70.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81702.1 - 2e-08 34.0 8.7 2e-08 34.0 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KXX81703.1 - 1e-28 98.1 5.7 1.5e-07 30.9 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KXX81703.1 - 5e-05 21.6 0.6 0.00074 17.7 0.0 2.6 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KXX81703.1 - 0.0069 15.8 0.1 0.14 11.6 0.0 2.3 1 1 2 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 KXX81703.1 - 0.017 13.4 0.0 1 7.5 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain DUF1513 PF07433.6 KXX81703.1 - 0.02 13.7 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF3312 PF11768.3 KXX81703.1 - 0.035 12.3 0.0 0.11 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Oxysterol_BP PF01237.13 KXX81704.1 - 1.5e-90 303.2 0.0 1.8e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein UCH PF00443.24 KXX81705.1 - 2.3e-40 138.4 0.0 2.3e-34 118.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX81705.1 - 5.4e-13 49.0 0.0 1.3e-09 37.9 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Hamartin PF04388.7 KXX81705.1 - 6.6 5.2 7.1 9.9 4.6 5.0 1.2 1 0 0 1 1 1 0 Hamartin protein TPR_12 PF13424.1 KXX81706.1 - 2.5e-09 36.9 4.8 0.00011 22.0 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX81706.1 - 2.1e-08 34.3 2.9 0.00012 22.3 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX81706.1 - 8.9e-08 31.6 0.4 0.0041 16.7 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KXX81706.1 - 1.5e-07 30.7 0.4 0.028 14.3 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX81706.1 - 2.9e-07 29.7 0.0 0.0088 15.7 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX81706.1 - 1.2e-06 29.0 9.6 5.7e-05 23.6 0.4 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81706.1 - 5.5e-06 26.5 9.5 0.48 11.2 0.0 6.2 5 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX81706.1 - 0.0002 21.4 0.1 0.017 15.2 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KXX81706.1 - 0.0013 18.2 0.0 0.29 10.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KXX81706.1 - 0.0028 17.3 0.0 0.17 11.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX81706.1 - 0.0033 17.7 3.7 21 5.8 0.0 5.5 6 1 0 6 6 5 0 Tetratricopeptide repeat DUF2681 PF10883.3 KXX81706.1 - 0.034 14.3 0.7 0.087 13.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TPR_10 PF13374.1 KXX81706.1 - 0.075 12.9 1.1 8.2 6.5 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KXX81706.1 - 0.076 12.2 0.4 0.5 9.6 0.0 2.4 3 0 0 3 3 3 0 SHNi-TPR TPR_4 PF07721.9 KXX81706.1 - 0.42 11.1 12.9 0.59 10.7 0.2 4.2 4 0 0 4 4 2 0 Tetratricopeptide repeat RWD PF05773.17 KXX81707.1 - 1.3e-22 79.8 0.2 2.2e-22 79.0 0.2 1.4 1 0 0 1 1 1 1 RWD domain KfrA_N PF11740.3 KXX81707.1 - 0.47 10.9 12.3 3.4 8.1 1.8 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3886 PF13025.1 KXX81707.1 - 1.9 8.4 11.8 7 6.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) CPL PF08144.6 KXX81708.1 - 2.2e-17 63.2 0.0 2.5e-16 59.8 0.0 2.6 3 0 0 3 3 3 1 CPL (NUC119) domain CTI PF06934.6 KXX81708.1 - 0.016 13.5 0.1 0.025 12.8 0.1 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) COPR5 PF15340.1 KXX81708.1 - 0.063 13.6 2.5 0.094 13.0 0.2 2.4 2 0 0 2 2 2 0 Cooperator of PRMT5 family LRR19-TM PF15176.1 KXX81709.1 - 0.021 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Sporozoite_P67 PF05642.6 KXX81709.1 - 0.44 8.3 3.0 0.55 8.0 2.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpb4 PF03874.11 KXX81710.1 - 9.6e-29 99.7 0.8 1.2e-28 99.5 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 KXX81711.1 - 9.7e-14 50.6 0.7 0.89 9.5 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat HTH_29 PF13551.1 KXX81712.1 - 4.4e-07 30.0 0.2 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KXX81712.1 - 3.1e-05 23.4 1.4 0.00032 20.2 0.2 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 KXX81712.1 - 0.011 15.2 0.3 0.072 12.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.1 KXX81712.1 - 0.025 15.3 2.8 0.074 13.8 0.0 3.0 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KXX81712.1 - 0.042 13.9 0.1 0.43 10.6 0.0 2.6 2 1 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.1 KXX81712.1 - 0.09 12.3 0.2 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.15 KXX81712.1 - 0.14 11.8 0.0 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Sugar_tr PF00083.19 KXX81713.1 - 1.3e-30 106.4 31.8 1.7e-19 69.7 5.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KXX81713.1 - 4e-23 81.7 24.1 2.3e-17 62.7 8.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Acetate_kinase PF00871.12 KXX81714.1 - 2e-86 289.9 0.0 2.4e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1908 PF08926.6 KXX81715.1 - 0.046 12.4 0.7 0.066 11.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) RIC1 PF07064.8 KXX81716.1 - 3.1e-90 302.1 0.1 4.3e-90 301.6 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KXX81716.1 - 5.3e-05 22.9 1.8 0.29 11.0 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.7 KXX81716.1 - 0.098 12.3 0.3 0.95 9.2 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GST_N_3 PF13417.1 KXX81717.1 - 8.1e-19 67.6 0.0 1.8e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX81717.1 - 3.1e-15 55.8 0.0 6.2e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX81717.1 - 1.7e-07 31.0 1.7 3.5e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX81717.1 - 3.8e-05 23.6 0.0 8.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KXX81717.1 - 0.00022 21.3 0.0 0.00079 19.5 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAD_binding_7 PF13241.1 KXX81717.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CK_II_beta PF01214.13 KXX81718.1 - 8.1e-73 243.8 0.1 1.1e-72 243.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Nop14 PF04147.7 KXX81718.1 - 0.17 9.7 3.4 0.23 9.3 2.4 1.2 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KXX81718.1 - 3.7 7.9 9.7 8.9 6.7 6.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAP2 PF01569.16 KXX81719.1 - 2.2e-20 72.6 3.8 2.6e-20 72.3 0.2 2.6 2 2 0 2 2 2 1 PAP2 superfamily TRP PF06011.7 KXX81720.1 - 4.3e-89 299.1 24.1 6.2e-88 295.2 16.7 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX81720.1 - 1.4e-30 106.1 0.0 2.1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain HATPase_c_3 PF13589.1 KXX81721.1 - 5.5e-11 42.2 0.0 9.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KXX81721.1 - 3.5e-09 36.3 0.1 5.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KXX81721.1 - 3.2e-05 23.3 0.0 6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain IF3_C PF00707.17 KXX81722.1 - 5.7e-12 45.2 0.1 9.6e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KXX81722.1 - 0.00021 20.7 0.5 0.004 16.5 0.4 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Arm PF00514.18 KXX81723.1 - 7.2e-70 228.6 29.8 3.4e-13 48.8 0.1 11.1 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KXX81723.1 - 2.6e-22 78.9 15.7 9.3e-07 29.0 0.2 7.6 2 2 1 5 5 5 5 HEAT repeats HEAT PF02985.17 KXX81723.1 - 1.5e-17 62.0 15.7 0.053 13.6 0.1 9.4 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 KXX81723.1 - 2.3e-17 62.9 14.6 0.00039 20.8 0.2 8.3 5 2 4 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 KXX81723.1 - 2.9e-11 42.4 8.6 5.6e-07 28.2 0.3 3.4 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 KXX81723.1 - 2e-10 40.2 6.2 0.0083 15.2 0.1 3.7 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 KXX81723.1 - 3.1e-10 39.6 2.5 0.0016 17.6 0.0 3.9 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 KXX81723.1 - 1.1e-09 36.8 0.2 2.8e-09 35.4 0.1 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Vpu PF00558.14 KXX81723.1 - 0.013 15.0 1.5 0.022 14.3 0.2 2.0 2 0 0 2 2 2 0 Vpu protein HEAT_PBS PF03130.11 KXX81723.1 - 0.014 15.8 7.2 76 4.2 0.1 6.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 KXX81723.1 - 0.038 14.3 0.4 1.6 9.1 0.0 3.3 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region CBS PF00571.23 KXX81724.1 - 1.3e-33 114.5 6.2 4.8e-14 51.8 0.2 4.3 4 0 0 4 4 4 4 CBS domain bZIP_1 PF00170.16 KXX81725.1 - 0.99 9.4 4.4 15 5.6 0.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor PBP PF01161.15 KXX81726.1 - 3e-12 46.5 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPT PF03151.11 KXX81727.1 - 4.7e-28 97.7 13.5 4.7e-28 97.7 9.3 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 KXX81727.1 - 7.3e-07 28.4 17.8 0.0016 17.4 3.4 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KXX81727.1 - 1.5e-05 25.0 36.8 5.3e-05 23.2 6.9 2.9 3 0 0 3 3 3 2 EamA-like transporter family COMPASS-Shg1 PF05205.7 KXX81728.1 - 1.7e-25 89.3 0.0 4.3e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Rox3 PF08633.5 KXX81729.1 - 3.8e-58 196.9 1.0 8.9e-58 195.7 0.0 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit Ribosomal_L4 PF00573.17 KXX81730.1 - 5.5e-45 153.1 0.0 6.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Herpes_gE PF02480.11 KXX81731.1 - 0.0012 17.1 0.0 0.0022 16.3 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 KXX81731.1 - 0.008 15.6 0.2 0.008 15.6 0.2 2.4 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 KXX81731.1 - 0.015 14.8 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BAF1_ABF1 PF04684.8 KXX81731.1 - 4.5 6.0 12.9 6.4 5.5 8.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PGAP1 PF07819.8 KXX81732.1 - 2.9e-07 30.3 0.1 1.3e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KXX81732.1 - 7e-07 28.7 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KXX81732.1 - 2.1e-06 27.5 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX81732.1 - 8.6e-06 25.7 1.4 3e-05 24.0 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KXX81732.1 - 0.0052 16.5 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF4463 PF14703.1 KXX81732.1 - 0.011 16.2 2.7 0.024 15.1 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Abhydrolase_1 PF00561.15 KXX81732.1 - 0.086 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 KXX81732.1 - 0.12 11.4 0.1 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KXX81732.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KXX81732.1 - 0.18 11.9 0.8 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain DUF2305 PF10230.4 KXX81732.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF3987 PF13148.1 KXX81732.1 - 5.2 5.5 12.6 7.8 4.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribosomal_S3Ae PF01015.13 KXX81733.1 - 4.2e-81 270.9 3.0 5.1e-81 270.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 KXX81733.1 - 0.012 15.7 0.1 0.067 13.3 0.0 2.2 2 1 0 2 2 2 0 Syntaxin Abhydrolase_6 PF12697.2 KXX81735.1 - 1.5e-31 110.0 0.0 3.5e-31 108.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX81735.1 - 1.3e-19 70.7 0.0 3.5e-18 65.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX81735.1 - 2.3e-13 50.1 0.0 6.5e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX81735.1 - 5.5e-05 22.8 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KXX81735.1 - 0.00026 21.2 0.0 0.00035 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 KXX81735.1 - 0.0007 19.0 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 KXX81735.1 - 0.005 16.5 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 KXX81735.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX81735.1 - 0.042 13.6 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 KXX81735.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase PF07224.6 KXX81735.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ras PF00071.17 KXX81736.1 - 5.9e-48 162.3 0.0 6.9e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX81736.1 - 1e-14 55.0 0.0 1.4e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX81736.1 - 3.8e-09 36.0 0.0 4.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KXX81736.1 - 0.00059 19.7 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KXX81736.1 - 0.001 19.0 0.1 0.0029 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KXX81736.1 - 0.0023 17.4 0.1 0.0047 16.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KXX81736.1 - 0.0026 17.2 0.0 0.0048 16.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KXX81736.1 - 0.0037 17.4 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 KXX81736.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KXX81736.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KXX81736.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX81736.1 - 0.047 13.9 0.0 0.086 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KXX81736.1 - 0.057 13.3 0.0 0.092 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KXX81736.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KXX81736.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KXX81736.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 KXX81736.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KXX81736.1 - 0.13 13.0 0.1 0.2 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRP72 PF08492.7 KXX81737.1 - 1.3e-15 57.4 12.0 1.3e-15 57.4 8.3 1.9 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_4 PF07721.9 KXX81737.1 - 0.0012 19.0 11.8 0.72 10.4 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX81737.1 - 0.0017 18.1 20.0 2.7 8.1 0.2 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX81737.1 - 0.0021 18.1 6.9 0.13 12.4 0.6 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KXX81737.1 - 0.0043 16.9 17.1 0.14 12.1 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81737.1 - 0.045 14.4 35.5 3.9 8.3 0.0 9.6 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX81737.1 - 0.11 12.8 27.3 1.8 8.9 0.0 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3195 PF11424.3 KXX81737.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) TPR_11 PF13414.1 KXX81737.1 - 0.36 10.5 13.4 2.2 7.9 0.1 5.3 6 0 0 6 6 6 0 TPR repeat TPR_16 PF13432.1 KXX81737.1 - 1.9 9.2 43.2 0.74 10.5 7.5 7.1 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KXX81737.1 - 1.9 8.2 10.5 13 5.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M14 PF00246.19 KXX81739.1 - 2.3e-70 237.3 0.0 2.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 KXX81739.1 - 0.087 11.8 0.0 7.8 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Sec7 PF01369.15 KXX81740.1 - 2.2e-40 138.3 0.0 4.3e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KXX81740.1 - 8.7e-05 22.6 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KXX81740.1 - 0.00024 21.2 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 PH domain GTP_CH_N PF12471.3 KXX81741.1 - 8.4e-87 289.8 0.1 4.7e-85 284.1 0.0 2.2 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KXX81741.1 - 5.1e-17 61.6 0.0 8.5e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 KXX81742.1 - 9.8e-25 86.0 0.7 9.8e-25 86.0 0.5 2.1 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like zf-BED PF02892.10 KXX81742.1 - 0.19 11.5 3.7 0.27 11.0 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 KXX81742.1 - 0.25 11.3 6.3 0.14 12.0 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger NAP PF00956.13 KXX81744.1 - 5.4e-88 294.2 6.8 5.4e-88 294.2 4.7 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.3 KXX81745.1 - 3.3e-38 130.1 0.0 7.4e-38 129.0 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 KXX81745.1 - 8.9e-29 100.1 0.0 1.8e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KXX81745.1 - 2.8e-27 96.1 0.0 4.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX81745.1 - 1.6e-15 58.0 0.0 7.3e-14 52.6 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KXX81745.1 - 0.00045 19.6 0.0 0.001 18.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KXX81745.1 - 0.03 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KXX81745.1 - 0.18 11.3 0.0 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PI3K_p85B PF02192.11 KXX81745.1 - 0.26 10.7 1.8 0.77 9.2 0.1 2.5 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain CMAS PF02353.15 KXX81746.1 - 3.2e-43 147.7 0.6 5.5e-43 147.0 0.4 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KXX81746.1 - 7.5e-15 55.2 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX81746.1 - 1.4e-13 50.9 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX81746.1 - 2e-13 50.2 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX81746.1 - 3.9e-11 43.5 0.0 8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81746.1 - 3.7e-09 36.9 0.0 7.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX81746.1 - 8.5e-08 31.4 0.0 2e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KXX81746.1 - 3.9e-07 29.5 0.0 6.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KXX81746.1 - 2.1e-05 24.8 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81746.1 - 0.00024 21.1 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81746.1 - 0.00024 20.2 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 KXX81746.1 - 0.039 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 KXX81746.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 KXX81747.1 - 9e-66 221.6 0.0 1.1e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81747.1 - 9.2e-30 103.5 0.0 1.2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX81747.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like UCH PF00443.24 KXX81748.1 - 8.8e-33 113.5 0.0 1.7e-32 112.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Octopine_DH PF02317.12 KXX81748.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Fungal_trans PF04082.13 KXX81750.1 - 6.9e-32 110.3 0.1 1.7e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX81750.1 - 1.8e-10 40.5 11.5 3e-10 39.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HCO3_cotransp PF00955.16 KXX81751.1 - 1.7e-68 231.5 13.4 4e-40 137.9 2.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family Serglycin PF04360.7 KXX81751.1 - 0.037 13.7 5.5 0.077 12.7 3.8 1.5 1 0 0 1 1 1 0 Serglycin Glypican PF01153.14 KXX81751.1 - 0.47 9.0 0.8 0.65 8.5 0.5 1.1 1 0 0 1 1 1 0 Glypican Peptidase_M41 PF01434.13 KXX81752.1 - 2.2e-75 252.7 0.0 2.2e-75 252.7 0.0 1.8 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.24 KXX81752.1 - 4.8e-43 146.5 0.0 1.5e-42 144.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KXX81752.1 - 1.2e-09 38.2 0.0 2.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 KXX81752.1 - 0.0014 18.8 0.0 0.086 12.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX81752.1 - 0.0015 18.3 0.0 0.0077 15.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX81752.1 - 0.0047 16.6 0.4 0.021 14.5 0.3 2.1 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KXX81752.1 - 0.0061 15.9 0.0 0.022 14.1 0.0 1.9 1 1 0 1 1 1 1 IstB-like ATP binding protein Spore_coat_CotO PF14153.1 KXX81752.1 - 0.0077 15.6 18.7 0.014 14.8 13.0 1.3 1 0 0 1 1 1 1 Spore coat protein CotO TIP49 PF06068.8 KXX81752.1 - 0.0098 14.6 0.1 0.02 13.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KXX81752.1 - 0.022 14.6 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 KXX81752.1 - 0.025 13.2 6.1 0.036 12.7 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_17 PF13207.1 KXX81752.1 - 0.034 14.9 0.0 0.17 12.7 0.0 2.3 2 1 0 2 2 1 0 AAA domain Ycf1 PF05758.7 KXX81752.1 - 0.036 11.8 7.7 0.047 11.4 5.4 1.1 1 0 0 1 1 1 0 Ycf1 RuvB_N PF05496.7 KXX81752.1 - 0.037 13.0 0.0 0.037 13.0 0.0 1.8 2 0 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX81752.1 - 0.05 13.5 0.1 0.05 13.5 0.1 3.0 2 1 1 3 3 2 0 AAA ATPase domain AAA_25 PF13481.1 KXX81752.1 - 0.061 12.7 0.3 0.4 10.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain Band_3_cyto PF07565.8 KXX81752.1 - 0.084 12.3 7.8 0.27 10.7 5.4 1.9 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDK5_activator PF03261.10 KXX81752.1 - 0.56 9.4 7.6 0.86 8.8 5.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4175 PF13779.1 KXX81752.1 - 0.7 7.5 40.7 1 6.9 28.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_28 PF13521.1 KXX81752.1 - 0.75 9.7 0.0 0.75 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF4557 PF15101.1 KXX81752.1 - 0.94 9.2 18.2 3 7.6 12.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_18 PF13238.1 KXX81752.1 - 0.98 9.7 0.0 0.98 9.7 0.0 2.5 2 0 0 2 2 1 0 AAA domain Zip PF02535.17 KXX81752.1 - 1.2 8.0 6.1 1.8 7.4 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_LMP2 PF07415.6 KXX81752.1 - 1.3 7.5 9.8 2.5 6.5 6.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Sec62 PF03839.11 KXX81752.1 - 1.3 8.3 10.0 2.5 7.4 6.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 OmpH PF03938.9 KXX81752.1 - 1.4 8.8 37.4 0.044 13.7 21.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PAT1 PF09770.4 KXX81752.1 - 1.7 6.8 42.3 2.5 6.2 29.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 KXX81752.1 - 2.6 6.7 27.7 4.9 5.8 19.2 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 KXX81752.1 - 3.5 7.2 23.8 1.2 8.8 14.3 1.8 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.7 KXX81752.1 - 3.6 6.0 17.2 5.5 5.4 11.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 KXX81752.1 - 4.5 7.0 22.0 7.5 6.3 15.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IF-2B PF01008.12 KXX81754.1 - 6e-44 150.1 0.0 1.3e-43 149.0 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_S24 PF00717.18 KXX81755.1 - 2.7e-08 33.3 0.1 6.3e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KXX81755.1 - 1.7e-06 27.6 0.0 3.1e-05 23.4 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 DUF605 PF04652.11 KXX81755.1 - 0.73 9.1 4.8 0.94 8.8 3.3 1.1 1 0 0 1 1 1 0 Vta1 like Catalase PF00199.14 KXX81756.1 - 2.6e-146 487.2 0.6 3.3e-146 486.8 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KXX81756.1 - 3.4e-12 46.0 0.0 6.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Sec5 PF15469.1 KXX81756.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF605 PF04652.11 KXX81757.1 - 0.042 13.2 15.8 0.047 13.0 10.9 1.1 1 0 0 1 1 1 0 Vta1 like Alb1 PF09135.6 KXX81758.1 - 1.7e-24 86.5 10.2 1.7e-24 86.5 7.1 1.6 2 0 0 2 2 2 1 Alb1 bZIP_1 PF00170.16 KXX81759.1 - 3e-08 33.4 5.1 5.6e-08 32.6 3.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX81759.1 - 1.2e-05 25.0 3.4 1.2e-05 25.0 2.3 1.7 2 0 0 2 2 2 1 Basic region leucine zipper Rep_fac-A_3 PF08661.6 KXX81760.1 - 6.3e-22 77.5 0.0 7e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-like PF12869.2 KXX81760.1 - 0.007 15.8 0.4 0.0092 15.4 0.3 1.2 1 0 0 1 1 1 1 tRNA_anti-like GATA PF00320.22 KXX81761.1 - 0.00064 19.0 6.7 0.013 14.8 1.3 2.5 2 0 0 2 2 2 2 GATA zinc finger Pyr_redox PF00070.22 KXX81762.1 - 1.1e-12 48.2 0.1 9.8e-11 41.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX81762.1 - 2.6e-11 43.8 0.0 3.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX81762.1 - 7.3e-08 32.7 0.0 3.3e-06 27.3 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX81762.1 - 0.00084 18.3 1.8 0.26 10.1 0.0 3.2 2 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KXX81762.1 - 0.0022 17.8 1.1 1.1 9.0 0.0 3.9 2 2 2 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KXX81762.1 - 0.0023 16.9 0.0 0.0077 15.1 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 KXX81762.1 - 0.025 14.5 0.1 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain PBP PF01161.15 KXX81764.1 - 4.4e-11 42.8 0.0 6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_C78 PF07910.8 KXX81765.1 - 1.7e-66 223.4 0.0 2.2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C47 PF05543.8 KXX81765.1 - 0.056 12.8 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Staphopain peptidase C47 AAA_18 PF13238.1 KXX81767.1 - 5e-27 94.7 0.7 8.2e-27 94.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX81767.1 - 7.4e-15 55.8 0.7 1.4e-14 54.9 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX81767.1 - 4.8e-06 26.5 0.0 0.00014 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KXX81767.1 - 2.9e-05 23.9 0.1 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase SKI PF01202.17 KXX81767.1 - 0.0001 22.1 0.2 0.00045 20.1 0.1 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.24 KXX81767.1 - 0.00019 21.6 0.0 0.00055 20.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KXX81767.1 - 0.00033 20.6 0.4 0.00068 19.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KXX81767.1 - 0.0024 17.7 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_22 PF13401.1 KXX81767.1 - 0.0037 17.3 0.1 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KXX81767.1 - 0.0044 16.2 0.0 0.0099 15.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KXX81767.1 - 0.0086 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.1 KXX81767.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 KXX81767.1 - 0.03 13.6 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.9 KXX81767.1 - 0.046 13.4 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KXX81767.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KXX81767.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KXX81767.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KXX81767.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Ham1p_like PF01725.11 KXX81768.1 - 2.5e-50 170.4 0.0 2.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family WAPL PF07814.8 KXX81769.1 - 1.2e-17 63.6 0.2 2.3e-17 62.7 0.1 1.5 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF1206 PF06724.6 KXX81769.1 - 4.9 6.9 5.7 8.2 6.2 1.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) UPRTase PF14681.1 KXX81770.1 - 2e-80 268.8 0.0 2.6e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KXX81770.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KXX81770.1 - 0.12 12.0 0.3 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Ras PF00071.17 KXX81771.1 - 1.1e-44 151.7 0.0 1.2e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX81771.1 - 2.4e-13 50.5 0.0 3.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX81771.1 - 5.8e-07 28.9 0.0 7e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KXX81771.1 - 5.1e-06 26.0 0.0 3.1e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX81771.1 - 7.7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KXX81771.1 - 0.00071 18.8 0.0 0.0019 17.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KXX81771.1 - 0.013 14.8 0.0 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 KXX81771.1 - 0.034 14.0 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KXX81771.1 - 0.11 12.3 0.1 2.4 8.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Myosin_head PF00063.16 KXX81772.1 - 2.3e-240 799.3 0.0 2.3e-240 799.3 0.0 1.7 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 KXX81772.1 - 1e-34 118.5 3.4 2.9e-34 117.0 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KXX81772.1 - 2.9e-16 57.4 33.0 1.9e-06 26.9 0.6 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 KXX81772.1 - 2e-05 23.9 2.0 3.2e-05 23.2 0.9 1.6 1 1 0 1 1 1 1 Reovirus sigma C capsid protein GAS PF13851.1 KXX81772.1 - 0.00029 20.1 12.4 0.00029 20.1 8.6 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 KXX81772.1 - 0.00094 18.7 19.2 0.00094 18.7 13.3 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family AAA_22 PF13401.1 KXX81772.1 - 0.0027 17.8 0.0 0.011 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 KXX81772.1 - 0.0043 16.8 0.2 0.0043 16.8 0.2 3.7 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) AAA_19 PF13245.1 KXX81772.1 - 0.021 14.5 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Hemerythrin PF01814.18 KXX81772.1 - 0.056 13.6 7.4 0.051 13.7 3.6 2.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Baculo_PEP_C PF04513.7 KXX81772.1 - 0.5 10.1 7.7 2.9 7.6 5.3 2.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 KXX81772.1 - 2 7.3 28.8 0.32 10.0 14.6 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 tRNA-synt_2b PF00587.20 KXX81773.1 - 4e-36 124.1 0.0 6.9e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KXX81773.1 - 2.6e-18 65.9 5.4 5.2e-18 65.0 3.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KXX81773.1 - 0.03 13.9 2.0 0.057 13.0 1.4 1.4 1 0 0 1 1 1 0 Mnd1 family DNA_topoisoIV PF00521.15 KXX81773.1 - 0.04 12.7 1.5 0.68 8.7 1.3 2.0 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A SYCE1 PF15233.1 KXX81773.1 - 0.065 13.1 2.7 0.14 12.0 1.9 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 2-Hacid_dh_C PF02826.14 KXX81774.1 - 4e-52 175.9 0.0 6.5e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX81774.1 - 6.7e-38 129.1 0.1 9e-38 128.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KXX81774.1 - 1.7e-05 24.7 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 KXX81774.1 - 0.00049 19.5 0.1 0.0017 17.8 0.1 1.9 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 KXX81774.1 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KXX81774.1 - 0.0028 17.0 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Cyt-b5 PF00173.23 KXX81775.1 - 2.6e-19 68.7 0.2 2.9e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EMP24_GP25L PF01105.19 KXX81777.1 - 6.4e-41 140.0 0.0 7.4e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KXX81777.1 - 0.028 12.6 0.2 0.035 12.3 0.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4337 PF14235.1 KXX81777.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MIS13 PF08202.6 KXX81779.1 - 3.4e-61 206.9 0.0 6.9e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Chitin_synth_1 PF01644.12 KXX81780.1 - 7.9e-72 240.3 0.0 1.2e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KXX81780.1 - 1.5e-26 91.8 0.1 2.8e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KXX81780.1 - 2.7e-26 92.0 0.0 6.8e-22 77.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KXX81780.1 - 3.8e-09 36.5 7.6 3.8e-09 36.5 5.2 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX81780.1 - 9.7e-09 35.3 0.0 9.6e-08 32.0 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 IlvN PF07991.7 KXX81781.1 - 1.8e-46 157.5 0.0 2.6e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KXX81781.1 - 6.3e-46 155.9 0.0 9e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KXX81781.1 - 0.069 13.5 0.3 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TPR_12 PF13424.1 KXX81784.1 - 6.5e-12 45.2 11.9 8.2e-05 22.4 0.3 4.2 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KXX81784.1 - 1.3e-09 37.2 2.4 0.028 14.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KXX81784.1 - 1.4e-07 30.7 6.1 0.027 14.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX81784.1 - 8.1e-07 28.4 7.8 0.0016 18.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX81784.1 - 1.3e-06 27.9 10.4 0.027 14.0 0.1 3.8 4 1 0 4 4 4 3 TPR repeat TPR_10 PF13374.1 KXX81784.1 - 5.8e-06 26.0 10.0 9e-05 22.2 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KXX81784.1 - 0.011 15.8 3.1 0.068 13.3 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KXX81784.1 - 0.026 14.9 1.1 1.4 9.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.1 KXX81784.1 - 0.042 12.9 1.2 0.11 11.6 0.1 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_8 PF13181.1 KXX81784.1 - 0.094 12.5 7.7 2.2 8.2 0.0 4.1 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX81784.1 - 0.13 12.9 5.7 12 6.8 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX81784.1 - 0.25 12.0 7.2 0.29 11.8 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 KXX81784.1 - 2.6 7.9 5.9 11 5.9 0.1 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain bZIP_1 PF00170.16 KXX81785.1 - 2.3e-08 33.8 3.7 2.3e-08 33.8 2.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KXX81785.1 - 1.2e-05 25.0 5.2 1.2e-05 25.0 3.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KXX81785.1 - 0.013 15.7 7.5 0.013 15.7 5.2 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 KXX81785.1 - 0.022 14.3 0.4 0.024 14.2 0.3 1.1 1 0 0 1 1 1 0 IncA protein BCL9 PF11502.3 KXX81785.1 - 0.072 12.6 0.4 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Dicty_REP PF05086.7 KXX81785.1 - 0.24 9.1 0.6 0.27 8.9 0.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_DNAp_acc PF04929.7 KXX81785.1 - 2 7.2 4.8 2.7 6.8 3.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3433 PF11915.3 KXX81786.1 - 3.4e-48 161.7 12.5 3.7e-26 91.1 0.8 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pho86 PF11124.3 KXX81786.1 - 0.11 11.4 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 TRP PF06011.7 KXX81787.1 - 5.9e-151 502.9 28.3 7.1e-151 502.6 19.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX81787.1 - 8.1e-42 142.6 0.5 1.4e-41 141.8 0.3 1.4 1 0 0 1 1 1 1 ML-like domain EphA2_TM PF14575.1 KXX81787.1 - 0.25 11.7 0.9 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4079 PF13301.1 KXX81787.1 - 8.4 6.3 20.7 2.1 8.3 3.9 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) Peptidase_M48 PF01435.13 KXX81788.1 - 1e-40 139.6 0.0 1.3e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Ras PF00071.17 KXX81789.1 - 1.1e-14 54.1 0.0 3.7e-09 36.1 0.0 2.7 2 1 0 2 2 2 2 Ras family Miro PF08477.8 KXX81789.1 - 8.4e-07 29.5 0.0 6e-06 26.7 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KXX81789.1 - 0.16 11.4 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-U1 PF06220.7 KXX81790.1 - 1.3e-21 75.8 3.8 2e-21 75.2 2.6 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KXX81790.1 - 0.0096 16.0 3.1 0.019 15.0 2.1 1.5 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding FAM60A PF15396.1 KXX81791.1 - 0.021 14.6 3.3 0.027 14.2 2.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NicO PF03824.11 KXX81791.1 - 0.025 13.8 4.1 0.038 13.2 2.8 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Claudin_2 PF13903.1 KXX81791.1 - 0.036 13.7 2.4 0.09 12.4 1.6 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SR-25 PF10500.4 KXX81791.1 - 0.092 12.1 13.3 0.12 11.7 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3377 PF11857.3 KXX81791.1 - 0.23 11.1 1.1 0.4 10.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) PAP1 PF08601.5 KXX81791.1 - 0.23 11.0 10.5 0.26 10.9 7.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KXX81791.1 - 0.78 7.9 8.7 0.85 7.8 6.0 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 KXX81791.1 - 8.6 6.1 10.2 9.8 5.9 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HD PF01966.17 KXX81793.1 - 3.6e-05 23.7 0.1 0.00022 21.2 0.0 2.1 2 1 0 2 2 2 1 HD domain HDOD PF08668.7 KXX81793.1 - 0.04 13.1 0.0 0.078 12.2 0.0 1.5 1 1 0 1 1 1 0 HDOD domain SUR7 PF06687.7 KXX81794.1 - 3.6e-36 124.7 20.2 4.3e-36 124.4 14.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KXX81794.1 - 4 7.2 19.2 0.97 9.2 10.3 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Sdh5 PF03937.11 KXX81795.1 - 4e-23 80.8 0.1 1e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DUF3439 PF11921.3 KXX81795.1 - 2.1 8.0 5.4 3.7 7.3 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) IDO PF01231.13 KXX81796.1 - 8.1e-39 133.2 0.0 1.1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PALP PF00291.20 KXX81797.1 - 2e-61 207.9 0.4 2.4e-61 207.6 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ras PF00071.17 KXX81798.1 - 3.1e-51 172.9 0.0 5.8e-51 172.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KXX81798.1 - 2.7e-17 63.3 0.1 1.8e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX81798.1 - 0.00042 19.6 0.0 0.0011 18.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX81798.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KXX81798.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX81798.1 - 0.043 13.0 0.1 0.5 9.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KXX81798.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KXX81798.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Opy2 PF09463.5 KXX81799.1 - 0.00044 20.2 15.6 0.00075 19.5 10.8 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KXX81799.1 - 0.099 12.3 0.2 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain UQ_con PF00179.21 KXX81800.1 - 4e-36 123.5 0.0 5.5e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX81800.1 - 0.0082 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B CBM_20 PF00686.14 KXX81801.1 - 0.0057 16.2 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain DUF3827 PF12877.2 KXX81801.1 - 0.86 7.6 5.1 1.4 6.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) zf-PHD-like PF15446.1 KXX81803.1 - 5.3e-73 244.0 12.8 1.3e-72 242.7 8.9 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KXX81803.1 - 5.9e-56 189.4 0.0 8.8e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX81803.1 - 5.8e-14 51.7 0.0 1.8e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KXX81803.1 - 3.1e-07 29.4 1.6 8.9e-07 28.0 1.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KXX81803.1 - 1.3e-05 24.7 2.6 0.0028 17.2 0.2 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KXX81803.1 - 8.6e-05 22.0 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 KXX81803.1 - 0.0005 19.7 6.2 0.0005 19.7 4.3 3.5 2 2 1 3 3 3 1 PHD-finger AAA_22 PF13401.1 KXX81803.1 - 0.0027 17.8 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD_2 PF06733.10 KXX81803.1 - 0.033 13.5 0.7 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 DEAD_2 PCI PF01399.22 KXX81805.1 - 0.007 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rep_fac-A_C PF08646.5 KXX81806.1 - 5.1e-56 188.4 2.1 1.1e-53 180.8 0.6 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KXX81806.1 - 1.8e-19 69.4 0.0 4.4e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KXX81806.1 - 1.4e-18 66.5 2.4 6.3e-13 48.3 0.0 4.5 3 1 1 4 4 4 3 OB-fold nucleic acid binding domain zf-like PF04071.7 KXX81806.1 - 0.041 13.5 0.3 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain Amidohydro_2 PF04909.9 KXX81807.1 - 3.2e-21 76.1 0.1 4e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Clc-like PF07062.7 KXX81807.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Clc-like SpoU_methylase PF00588.14 KXX81809.1 - 1.7e-29 102.5 0.0 3.2e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KXX81809.1 - 1.5e-08 34.6 0.0 5.3e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding PLRV_ORF5 PF01690.12 KXX81809.1 - 0.89 8.6 7.3 1.2 8.1 5.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ribonuc_L-PSP PF01042.16 KXX81811.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP SUR7 PF06687.7 KXX81812.1 - 6.7e-25 87.9 9.5 7.9e-25 87.6 6.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KXX81812.1 - 2.1 8.0 13.7 27 4.4 9.5 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sulfate_transp PF00916.15 KXX81814.1 - 2.6e-06 26.6 1.3 2.6e-06 26.6 0.9 2.8 2 1 1 3 3 3 1 Sulfate transporter family Bromodomain PF00439.20 KXX81815.1 - 1.4e-24 85.7 0.1 2.6e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KXX81815.1 - 3.7e-09 36.6 0.2 1e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX81815.1 - 6.7e-09 35.6 0.3 1.8e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Fork_head PF00250.13 KXX81816.1 - 1.7e-11 43.9 0.1 3.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KXX81816.1 - 3.5e-06 27.0 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Aft1_HRA PF11786.3 KXX81818.1 - 9.2e-32 109.1 9.3 9.2e-32 109.1 6.4 3.4 4 1 0 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.3 KXX81818.1 - 2.1e-27 95.9 8.6 2.1e-27 95.9 6.0 4.1 3 2 1 5 5 5 1 Aft1 HRR domain Aft1_OSA PF11785.3 KXX81818.1 - 1.6e-19 70.1 11.1 1.6e-19 70.1 7.7 5.3 6 1 1 7 7 7 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KXX81818.1 - 2.5e-13 49.7 6.4 4.4e-13 48.9 4.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KXX81818.1 - 1.6e-06 27.8 7.4 3.4e-06 26.7 5.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KXX81818.1 - 0.0041 17.3 4.2 0.0041 17.3 2.9 2.2 3 0 0 3 3 3 1 bZIP Maf transcription factor Macoilin PF09726.4 KXX81818.1 - 0.032 12.5 9.2 0.047 11.9 6.3 1.3 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 KXX81818.1 - 0.32 10.5 1.3 0.6 9.6 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3450 PF11932.3 KXX81818.1 - 0.44 9.7 6.8 0.26 10.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GST_N_3 PF13417.1 KXX81819.1 - 6.7e-14 51.8 0.4 1.6e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX81819.1 - 7.9e-07 28.8 0.4 1.6e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KXX81819.1 - 4.1e-05 23.5 0.0 8.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RNA_pol_Rpb5_C PF01191.14 KXX81819.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Transferase PF02458.10 KXX81820.1 - 1.5e-17 63.1 0.0 2.7e-17 62.3 0.0 1.3 2 0 0 2 2 2 1 Transferase family CPSase_L_D2 PF02786.12 KXX81821.1 - 2.3e-113 376.6 0.2 4.9e-84 280.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KXX81821.1 - 3.3e-44 149.5 0.0 7.5e-44 148.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KXX81821.1 - 1.2e-43 148.8 0.0 2.1e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KXX81821.1 - 5.7e-41 139.4 0.0 1.2e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KXX81821.1 - 6.4e-41 138.8 0.0 3.7e-20 72.0 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KXX81821.1 - 1.6e-40 137.6 0.0 4.6e-40 136.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KXX81821.1 - 1.1e-37 129.6 0.2 4.8e-24 85.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KXX81821.1 - 4.6e-32 111.0 0.0 1.1e-31 109.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KXX81821.1 - 1.2e-22 80.0 0.1 4.9e-12 45.2 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KXX81821.1 - 8.6e-21 73.6 0.0 4.5e-20 71.3 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 KXX81821.1 - 2.1e-17 63.0 0.1 1.1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KXX81821.1 - 5.8e-16 58.4 0.5 3.5e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 KXX81821.1 - 5.8e-06 25.9 0.3 0.00022 20.7 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KXX81821.1 - 1.2e-05 25.2 0.5 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KXX81821.1 - 0.00019 21.0 0.1 1.1 8.8 0.0 3.1 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 KXX81821.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Ion_trans PF00520.26 KXX81822.1 - 5.3e-05 22.5 23.8 0.00046 19.4 15.4 2.4 1 1 0 1 1 1 1 Ion transport protein DUF3671 PF12420.3 KXX81822.1 - 6.3 6.8 9.4 14 5.7 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function MFS_1 PF07690.11 KXX81825.1 - 1.5e-34 119.2 46.5 1.5e-34 119.2 32.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX81825.1 - 1.6e-08 33.5 21.1 4.9e-08 31.9 14.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.8 KXX81826.1 - 1.4e-32 112.8 0.0 1.8e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KXX81826.1 - 3.3e-07 29.9 0.0 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX81826.1 - 5.3e-06 26.4 2.4 0.00012 22.0 1.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX81826.1 - 0.00018 21.3 0.0 0.0003 20.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX81826.1 - 0.038 13.5 0.2 0.083 12.4 0.2 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 KXX81827.1 - 1.3e-31 109.8 0.2 1.6e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX81827.1 - 1.4e-13 50.9 0.1 1.9e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX81827.1 - 5.7e-07 29.5 0.0 7.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX81827.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KXX81827.1 - 0.037 13.8 0.2 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1182 PF06681.8 KXX81827.1 - 0.073 12.2 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF2717 PF10911.3 KXX81827.1 - 0.15 11.5 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) Hydrophobin_2 PF06766.6 KXX81828.1 - 5.5e-24 83.6 8.3 6.8e-24 83.3 5.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin zf-C3Hc3H PF13891.1 KXX81828.1 - 0.02 14.9 2.8 1.4 9.0 0.1 2.3 1 1 1 2 2 2 0 Potential DNA-binding domain HeLo PF14479.1 KXX81829.1 - 2.1e-07 30.9 2.2 0.0001 22.1 0.9 3.0 3 1 0 3 3 3 1 Prion-inhibition and propagation RINGv PF12906.2 KXX81831.1 - 3.7e-16 58.9 9.6 6.2e-16 58.1 6.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KXX81831.1 - 0.052 13.3 7.9 0.1 12.4 5.5 1.5 1 0 0 1 1 1 0 Ring finger domain LRRC37AB_C PF14914.1 KXX81831.1 - 0.63 9.4 0.4 1.3 8.4 0.3 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zf-Apc11 PF12861.2 KXX81831.1 - 0.7 9.7 4.5 1.6 8.6 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KXX81831.1 - 1.6 8.4 7.3 2.7 7.6 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KXX81831.1 - 2.8 7.9 5.8 5.3 7.0 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DnaJ_CXXCXGXG PF00684.14 KXX81831.1 - 5.9 7.0 4.4 11 6.1 3.0 1.3 1 0 0 1 1 1 0 DnaJ central domain FAD_binding_4 PF01565.18 KXX81832.1 - 7.2e-21 74.1 3.8 1.9e-18 66.2 2.6 2.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX81832.1 - 1.9e-10 40.4 0.0 3.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KXX81833.1 - 3.9e-27 94.9 0.0 5.6e-26 91.0 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_1d PF00750.14 KXX81834.1 - 2e-80 270.2 4.6 4.2e-80 269.2 3.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KXX81834.1 - 1.5e-27 95.8 1.1 2.5e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KXX81834.1 - 1.8e-05 25.1 0.0 5.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain SIP1 PF04938.7 KXX81834.1 - 0.03 13.7 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) FAD_binding_8 PF08022.7 KXX81835.1 - 6.4e-16 58.1 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KXX81835.1 - 9.2e-14 51.6 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KXX81835.1 - 2.3e-11 43.8 12.2 2.3e-11 43.8 8.4 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KXX81835.1 - 0.075 13.1 11.6 0.62 10.2 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF1943 PF09172.6 KXX81837.1 - 0.032 13.0 0.8 2.4 6.9 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1943) DNA_PPF PF02916.10 KXX81837.1 - 0.2 11.7 2.5 0.41 10.7 1.7 1.5 1 0 0 1 1 1 0 DNA polymerase processivity factor Dynactin_p62 PF05502.8 KXX81838.1 - 2.2e-184 613.7 0.0 2.6e-184 613.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 KXX81838.1 - 0.041 13.8 0.7 0.041 13.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) ADH_N PF08240.7 KXX81839.1 - 1.4e-24 85.8 1.9 2.6e-24 85.0 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX81839.1 - 1.6e-13 50.3 0.1 4.1e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KXX81839.1 - 2.9e-05 23.3 0.1 4.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GATase PF00117.23 KXX81840.1 - 7.7e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C2 PF00648.16 KXX81841.1 - 1.9e-52 178.1 1.0 3.5e-36 124.7 0.4 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Ribosomal_S7e PF01251.13 KXX81843.1 - 1.3e-81 272.6 0.2 1.4e-81 272.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Peptidase_S8 PF00082.17 KXX81844.1 - 4.1e-48 163.9 0.0 1.1e-47 162.5 0.0 1.7 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KXX81844.1 - 5.9e-13 49.2 0.1 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KXX81844.1 - 2.1e-11 43.4 0.2 1e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 KXX81844.1 - 7.3e-05 22.4 0.0 0.00027 20.6 0.0 2.0 1 0 0 1 1 1 1 FlgD Ig-like domain Glyco_hydro_10 PF00331.15 KXX81845.1 - 2e-84 283.3 0.0 2.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Alpha-E PF04168.7 KXX81846.1 - 0.00065 19.1 2.0 0.0015 17.9 0.0 2.5 3 0 0 3 3 3 1 A predicted alpha-helical domain with a conserved ER motif. Dynamin_M PF01031.15 KXX81846.1 - 0.012 14.4 0.9 6.1 5.5 0.0 3.2 2 1 1 3 3 3 0 Dynamin central region DUF3223 PF11523.3 KXX81846.1 - 0.013 15.7 0.1 0.38 11.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3223) MCPsignal PF00015.16 KXX81846.1 - 0.017 14.6 4.2 0.063 12.8 0.1 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Apolipoprotein PF01442.13 KXX81846.1 - 0.094 12.2 10.2 15 5.0 2.3 3.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain XH PF03469.9 KXX81846.1 - 0.34 10.5 4.4 11 5.7 0.0 3.2 2 1 0 3 3 3 0 XH domain Syntaxin_2 PF14523.1 KXX81846.1 - 0.34 10.9 10.8 9.4 6.3 0.4 4.4 4 1 1 5 5 5 0 Syntaxin-like protein LANC_like PF05147.8 KXX81847.1 - 2.4e-21 75.6 0.0 9.5e-21 73.7 0.0 1.7 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein Ribosomal_S7e PF01251.13 KXX81848.1 - 1.3e-81 272.6 0.2 1.4e-81 272.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.7 KXX81850.1 - 1.4e-24 85.8 1.9 2.6e-24 85.0 1.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX81850.1 - 1.6e-13 50.3 0.1 4.1e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KXX81850.1 - 2.9e-05 23.3 0.1 4.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynactin_p62 PF05502.8 KXX81851.1 - 2.2e-184 613.7 0.0 2.6e-184 613.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 KXX81851.1 - 0.041 13.8 0.7 0.041 13.8 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Glyco_hydro_30 PF02055.11 KXX81852.1 - 5.3e-14 51.2 0.3 1.3e-08 33.5 0.0 2.6 3 0 0 3 3 3 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KXX81852.1 - 2.7e-09 36.4 4.9 2.6e-07 29.9 3.4 2.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 RHS_repeat PF05593.9 KXX81852.1 - 0.14 12.3 1.4 6.6 7.0 0.1 3.1 3 0 0 3 3 3 0 RHS Repeat EBP PF05241.7 KXX81853.1 - 0.00031 19.8 5.3 0.0005 19.1 3.7 1.5 1 1 0 1 1 1 1 Emopamil binding protein BolA PF01722.13 KXX81854.1 - 5.9e-16 58.1 0.0 8.5e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF3446 PF11928.3 KXX81854.1 - 0.12 12.5 2.2 0.18 12.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Peptidase_S8 PF00082.17 KXX81855.1 - 4.1e-48 163.9 0.0 1.1e-47 162.5 0.0 1.7 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KXX81855.1 - 5.9e-13 49.2 0.1 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KXX81855.1 - 2.1e-11 43.4 0.2 1e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 KXX81855.1 - 7.3e-05 22.4 0.0 0.00027 20.6 0.0 2.0 1 0 0 1 1 1 1 FlgD Ig-like domain Peptidase_C2 PF00648.16 KXX81856.1 - 2e-52 178.0 1.0 3.7e-36 124.6 0.4 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease TMEM171 PF15471.1 KXX81856.1 - 7.2 5.3 8.3 17 4.0 5.7 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 GATase PF00117.23 KXX81857.1 - 8e-07 28.6 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I EBP PF05241.7 KXX81858.1 - 0.00031 19.8 5.3 0.0005 19.1 3.7 1.5 1 1 0 1 1 1 1 Emopamil binding protein Glyco_hydro_30 PF02055.11 KXX81859.1 - 6e-14 51.1 0.3 1.3e-08 33.4 0.0 2.6 3 0 0 3 3 3 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KXX81859.1 - 2.8e-09 36.4 4.8 1.3e-08 34.1 0.0 2.4 1 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 RHS_repeat PF05593.9 KXX81859.1 - 0.15 12.2 1.4 6.7 7.0 0.1 3.1 3 0 0 3 3 3 0 RHS Repeat BolA PF01722.13 KXX81860.1 - 5.9e-16 58.1 0.0 8.5e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF3446 PF11928.3 KXX81860.1 - 0.12 12.5 2.2 0.18 12.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Cofilin_ADF PF00241.15 KXX81862.1 - 1.1e-22 80.3 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Orbi_VP7 PF00897.12 KXX81862.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 DIOX_N PF14226.1 KXX81863.1 - 0.00078 19.9 0.0 0.002 18.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX81863.1 - 0.0045 17.2 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KXX81864.1 - 0.00078 19.9 0.0 0.002 18.6 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KXX81864.1 - 0.0045 17.2 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cofilin_ADF PF00241.15 KXX81865.1 - 1.1e-22 80.3 0.0 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Orbi_VP7 PF00897.12 KXX81865.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 DUF4366 PF14283.1 KXX81867.1 - 0.012 15.0 0.2 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MitoNEET_N PF10660.4 KXX81867.1 - 0.13 12.1 0.5 0.3 10.9 0.0 1.8 2 1 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus ABC_cobalt PF09819.4 KXX81867.1 - 0.14 12.1 4.6 0.26 11.2 3.2 1.5 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF1700 PF08006.6 KXX81867.1 - 4.3 6.6 5.8 4.8 6.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Asp PF00026.18 KXX81868.1 - 1e-39 136.6 0.0 1.9e-39 135.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 KXX81869.1 - 1e-39 136.6 0.0 1.9e-39 135.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4366 PF14283.1 KXX81870.1 - 0.012 15.0 0.2 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MitoNEET_N PF10660.4 KXX81870.1 - 0.13 12.1 0.5 0.3 10.9 0.0 1.8 2 1 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus ABC_cobalt PF09819.4 KXX81870.1 - 0.14 12.1 4.6 0.26 11.2 3.2 1.5 1 1 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF1700 PF08006.6 KXX81870.1 - 4.3 6.6 5.8 4.8 6.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) PMT PF02366.13 KXX81871.1 - 2e-80 269.7 17.2 2e-80 269.7 11.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KXX81871.1 - 9e-19 67.7 0.7 3.6e-18 65.7 0.3 1.9 1 1 1 2 2 2 2 MIR domain Ammonium_transp PF00909.16 KXX81872.1 - 4.7e-111 371.0 26.3 3.1e-81 272.8 14.3 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Peptidase_C15 PF01470.12 KXX81873.1 - 3.1e-12 46.7 0.1 0.00014 21.7 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase IBR PF01485.16 KXX81874.1 - 3.7e-08 33.1 46.4 5.3e-06 26.2 9.5 3.8 3 1 1 4 4 4 2 IBR domain CAP_N PF01213.14 KXX81874.1 - 4.2 6.5 6.0 7.5 5.7 4.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Filament PF00038.16 KXX81875.1 - 0.00049 19.6 37.2 0.00049 19.6 25.8 6.1 3 2 2 5 5 5 3 Intermediate filament protein FIVAR PF07554.8 KXX81875.1 - 0.14 12.4 3.2 11 6.3 0.3 3.1 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain IncA PF04156.9 KXX81875.1 - 0.33 10.5 0.0 0.33 10.5 0.0 6.8 3 2 1 5 5 5 0 IncA protein XPG_N PF00752.12 KXX81877.1 - 2.2e-33 114.5 0.0 4.8e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KXX81877.1 - 3.5e-26 91.1 0.0 8.4e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KXX81877.1 - 0.0009 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing UIM PF02809.15 KXX81877.1 - 0.0039 16.6 3.7 0.0042 16.5 0.2 3.1 2 0 0 2 2 2 1 Ubiquitin interaction motif HHH PF00633.18 KXX81877.1 - 0.098 12.4 0.1 0.37 10.5 0.1 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Oxidored_FMN PF00724.15 KXX81878.1 - 4.4e-75 252.7 0.0 5.7e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Nitro_FeMo-Co PF02579.12 KXX81878.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor GHL6 PF14871.1 KXX81878.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 MFS_1 PF07690.11 KXX81879.1 - 1.7e-33 115.8 26.5 1.2e-32 112.9 19.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_capsid PF06112.6 KXX81880.1 - 7.1 6.6 9.9 11 6.0 6.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mito_carr PF00153.22 KXX81882.1 - 1.2e-59 198.0 2.3 7.5e-20 70.4 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF1708 PF08101.6 KXX81883.1 - 8e-161 535.5 0.0 1e-160 535.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.14 KXX81884.1 - 5e-25 87.7 0.1 7.1e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CDC27 PF09507.5 KXX81884.1 - 0.035 13.3 0.8 0.035 13.3 0.5 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Lectin_legB PF00139.14 KXX81884.1 - 0.049 12.9 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Legume lectin domain Metallophos PF00149.23 KXX81885.1 - 1.2e-16 60.7 3.4 3.3e-16 59.2 2.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_transf_28 PF03033.15 KXX81886.1 - 1.5e-21 76.6 0.1 1.5e-20 73.3 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KXX81886.1 - 4.5e-06 25.4 0.1 7.3e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KXX81886.1 - 5.3e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KXX81886.1 - 0.0011 19.0 0.0 0.0054 16.8 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain NAD_binding_10 PF13460.1 KXX81887.1 - 1.9e-25 89.9 0.1 3.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX81887.1 - 1.8e-10 40.4 0.0 1.3e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KXX81887.1 - 4e-06 26.4 0.0 0.011 15.1 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KXX81887.1 - 0.0019 18.1 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Peripla_BP_1 PF00532.16 KXX81887.1 - 0.0084 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family RmlD_sub_bind PF04321.12 KXX81887.1 - 0.043 12.6 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 KXX81887.1 - 0.052 13.2 0.2 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 KR domain PAF-AH_p_II PF03403.8 KXX81888.1 - 1.9e-52 177.8 0.0 6.9e-26 90.4 0.0 3.9 4 0 0 4 4 4 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KXX81888.1 - 1.5e-13 50.6 0.1 8.5e-13 48.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX81888.1 - 1.2e-08 35.1 0.6 4.3e-08 33.3 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KXX81888.1 - 4e-05 22.6 0.0 0.0057 15.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 KXX81888.1 - 0.00038 19.3 0.0 0.0051 15.6 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KXX81888.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF2424 PF10340.4 KXX81888.1 - 0.26 9.8 0.0 0.42 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF4407 PF14362.1 KXX81889.1 - 1.2 8.0 4.7 8.6 5.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spindle_Spc25 PF08234.7 KXX81890.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 1 1 2 2 2 0 Chromosome segregation protein Spc25 Mito_carr PF00153.22 KXX81891.1 - 1.5e-52 175.2 9.6 2.4e-19 68.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EFP_N PF08207.7 KXX81892.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Mob1_phocein PF03637.12 KXX81893.1 - 2.8e-40 137.8 1.0 9.1e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Methyltransf_31 PF13847.1 KXX81894.1 - 2.1e-14 53.3 0.1 3.3e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KXX81894.1 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 KXX81894.1 - 9.3e-12 44.6 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KXX81894.1 - 2e-10 41.2 0.1 5.1e-10 39.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX81894.1 - 7.1e-10 39.2 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX81894.1 - 6.5e-09 35.8 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KXX81894.1 - 5.4e-08 31.8 0.0 9e-08 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KXX81894.1 - 4.4e-07 30.2 0.0 9.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX81894.1 - 1.4e-06 27.7 0.2 3.6e-06 26.4 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KXX81894.1 - 7.1e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX81894.1 - 3.8e-05 24.0 0.0 9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KXX81894.1 - 6.7e-05 22.1 0.0 9.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KXX81894.1 - 0.00036 20.5 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 KXX81894.1 - 0.0015 18.1 0.2 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.9 KXX81894.1 - 0.0028 16.8 0.1 0.0052 15.9 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KXX81894.1 - 0.0048 16.5 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX81894.1 - 0.01 14.9 0.3 0.021 13.9 0.2 1.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 KXX81894.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 KXX81894.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KXX81894.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 KXX81894.1 - 0.03 13.9 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KXX81894.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 KXX81894.1 - 0.051 12.9 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 KXX81894.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 KXX81894.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PGM_PMM_I PF02878.11 KXX81895.1 - 3.6e-18 65.3 0.0 3.4e-08 33.0 0.0 2.9 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KXX81895.1 - 5.8e-14 52.2 0.1 3.4e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KXX81895.1 - 5.3e-11 42.3 1.0 2e-10 40.5 0.4 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ERCC4 PF02732.10 KXX81896.1 - 1e-31 109.5 0.1 1.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KXX81896.1 - 2.1e-05 24.6 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KXX81896.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix domain Lum_binding PF00677.12 KXX81897.1 - 2.2e-37 126.8 0.0 6.7e-19 67.5 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF3024 PF11225.3 KXX81898.1 - 0.065 13.1 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) KSHV_K1 PF11049.3 KXX81898.1 - 0.097 12.6 0.6 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus zf-C2H2 PF00096.21 KXX81900.1 - 0.015 15.5 2.6 0.015 15.5 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX81900.1 - 0.69 10.3 18.6 0.083 13.2 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Ribonuc_L-PSP PF01042.16 KXX81901.1 - 4.2e-38 129.8 0.2 4.9e-38 129.5 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Metallophos PF00149.23 KXX81902.1 - 9e-40 136.2 0.1 1.2e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.23 KXX81903.1 - 1.4e-21 77.4 0.4 7.9e-21 75.0 0.3 2.4 1 1 0 1 1 1 1 SET domain DUF87 PF01935.12 KXX81903.1 - 0.13 12.0 0.1 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 WD40 PF00400.27 KXX81904.1 - 8.2e-24 82.5 13.9 7.6e-11 41.4 0.1 10.2 11 0 0 11 11 11 5 WD domain, G-beta repeat SUR7 PF06687.7 KXX81905.1 - 4.6e-36 124.3 11.3 5.6e-36 124.0 7.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family F_actin_cap_B PF01115.12 KXX81906.1 - 6.3e-108 359.5 0.0 7.3e-108 359.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Glyco_transf_22 PF03901.12 KXX81907.1 - 2.6e-42 145.2 19.7 3.6e-42 144.8 13.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KXX81907.1 - 2.9 7.7 24.1 0.067 13.0 9.8 2.7 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Epimerase PF01370.16 KXX81909.1 - 8.1e-21 74.5 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KXX81909.1 - 3e-08 32.8 0.0 4.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KXX81909.1 - 4.4e-05 23.4 0.0 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KXX81909.1 - 7e-05 22.9 0.0 0.00024 21.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KXX81909.1 - 0.0059 15.5 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KXX81909.1 - 0.007 15.0 0.0 0.019 13.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KXX81909.1 - 0.068 12.1 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pil1 PF13805.1 KXX81910.1 - 3.7e-155 514.9 0.6 4.5e-155 514.6 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KXX81910.1 - 0.065 12.5 3.9 0.19 11.0 2.6 1.8 1 1 0 1 1 1 0 FAM92 protein LSM PF01423.17 KXX81911.1 - 4.9e-08 32.3 0.0 6.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KXX81911.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Glyco_hydro_3 PF00933.16 KXX81912.1 - 1.1e-84 283.9 0.0 1.7e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KXX81912.1 - 1.4e-75 253.6 0.0 3.4e-74 249.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KXX81912.1 - 4.8e-20 71.2 0.2 1.1e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KXX81912.1 - 1.2e-19 70.3 0.0 2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Glyco_transf_17 PF04724.8 KXX81913.1 - 2.1e-47 161.8 0.0 3e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 SLT_2 PF13406.1 KXX81913.1 - 0.00082 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain p450 PF00067.17 KXX81914.1 - 2.8e-80 270.1 0.0 3.7e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1506 PF07405.6 KXX81914.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) SR-25 PF10500.4 KXX81915.1 - 0.11 11.9 1.5 0.16 11.4 1.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MCM PF00493.18 KXX81916.1 - 5e-139 462.7 0.0 5e-139 462.7 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 KXX81916.1 - 1.2e-31 109.8 39.4 1.2e-31 109.8 27.3 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KXX81916.1 - 3.7e-21 75.8 0.1 8.8e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX81916.1 - 9.6e-08 31.4 0.0 6e-06 25.5 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX81916.1 - 2.2e-06 27.4 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KXX81916.1 - 0.0016 17.9 0.2 0.011 15.2 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KXX81916.1 - 0.0019 17.7 0.1 0.019 14.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 KXX81916.1 - 0.061 12.5 1.2 0.15 11.3 0.8 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 KXX81916.1 - 0.23 11.8 0.6 0.73 10.2 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain Band_7 PF01145.20 KXX81917.1 - 4.7e-24 85.2 5.4 4.7e-24 85.2 3.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 KXX81917.1 - 0.0042 16.0 3.7 0.006 15.5 2.6 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF2884 PF11101.3 KXX81917.1 - 0.0091 15.4 0.7 0.015 14.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) UCH PF00443.24 KXX81918.1 - 2.4e-48 164.5 0.0 5.3e-48 163.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX81918.1 - 4.4e-21 75.5 0.0 1.3e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.5 KXX81919.1 - 5.9e-17 62.1 0.5 1.1e-16 61.3 0.0 1.6 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus RNase_T PF00929.19 KXX81920.1 - 5.1e-07 30.1 0.0 0.0034 17.6 0.0 2.4 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 KXX81920.1 - 2.2 8.5 7.3 0.68 10.2 0.5 2.9 2 1 1 3 3 3 0 CHORD Glyco_transf_8 PF01501.15 KXX81921.1 - 1.3e-22 80.3 0.0 2.1e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 UcrQ PF02939.11 KXX81922.1 - 2.7e-34 116.8 0.4 3.2e-34 116.5 0.3 1.0 1 0 0 1 1 1 1 UcrQ family DUF1761 PF08570.5 KXX81923.1 - 1.6e-21 76.6 4.0 1.9e-21 76.3 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.13 KXX81924.1 - 5.2e-52 175.7 0.0 7.8e-52 175.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4091 PF13320.1 KXX81924.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) IF-2B PF01008.12 KXX81925.1 - 6.2e-38 130.4 0.0 1.2e-37 129.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cep57_MT_bd PF06657.8 KXX81925.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_L7Ae PF01248.21 KXX81926.1 - 2.3e-15 55.8 0.7 2.2e-14 52.7 0.5 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UBA PF00627.26 KXX81927.1 - 0.00013 21.6 0.1 0.00032 20.4 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CAF-1_p150 PF11600.3 KXX81927.1 - 0.0067 15.8 37.5 0.0096 15.3 26.0 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBX PF00789.15 KXX81927.1 - 0.045 13.8 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 UBX domain GATA PF00320.22 KXX81927.1 - 0.15 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2 PF00096.21 KXX81927.1 - 0.15 12.4 1.1 0.28 11.5 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Asp-B-Hydro_N PF05279.6 KXX81927.1 - 1.1 9.0 18.6 1.5 8.6 12.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.1 KXX81927.1 - 2 8.7 8.9 2.4 8.4 6.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2413 PF10310.4 KXX81927.1 - 3.8 6.2 23.7 5.9 5.5 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Motile_Sperm PF00635.21 KXX81928.1 - 4.7e-23 80.9 0.1 9.3e-23 79.9 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 KXX81928.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Reeler PF02014.11 KXX81928.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Reeler domain AMP-binding PF00501.23 KXX81929.1 - 3.2e-86 289.3 0.0 3.8e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX81929.1 - 7.3e-17 62.0 0.1 5.3e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KXX81929.1 - 0.00028 19.5 0.0 0.0028 16.2 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter HA2 PF04408.18 KXX81930.1 - 4.5e-22 77.9 0.0 4.5e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KXX81930.1 - 1.7e-21 76.1 0.0 3.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KXX81930.1 - 9e-12 44.6 0.0 2.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KXX81930.1 - 2.4e-06 27.1 0.1 4.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KXX81930.1 - 6.8e-05 23.0 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KXX81930.1 - 0.0062 15.4 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 KXX81930.1 - 0.0068 15.8 0.1 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KXX81930.1 - 0.02 14.6 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KXX81930.1 - 0.027 13.9 0.6 0.79 9.1 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KXX81930.1 - 0.033 13.7 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KXX81930.1 - 0.21 11.1 0.0 0.21 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KXX81930.1 - 3.5 7.9 0.0 3.5 7.9 0.0 2.8 2 1 0 2 2 1 0 AAA domain PRP38_assoc PF12871.2 KXX81931.1 - 0.0034 17.8 48.5 0.0034 17.8 33.6 13.0 8 4 2 10 10 10 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4366 PF14283.1 KXX81931.1 - 0.012 15.0 7.1 0.48 9.8 0.2 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) Ribosomal_60s PF00428.14 KXX81932.1 - 1.4e-27 95.8 14.0 1.8e-27 95.5 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_21 PF13506.1 KXX81932.1 - 0.094 11.9 0.3 0.11 11.7 0.2 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF2408 PF10303.4 KXX81933.1 - 2.7e-50 169.9 2.5 1.9e-29 102.5 0.0 4.6 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) YCII PF03795.9 KXX81934.1 - 3.4e-08 33.5 0.0 4.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UPF0150 PF03681.10 KXX81934.1 - 0.13 11.8 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) PS_Dcarbxylase PF02666.10 KXX81934.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase G-patch PF01585.18 KXX81935.1 - 6.7e-11 41.7 2.2 8.6e-11 41.4 0.5 2.0 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 KXX81935.1 - 7.9e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX81935.1 - 0.006 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX81935.1 - 0.087 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KXX81935.1 - 1 9.2 6.5 0.16 11.8 0.2 2.7 3 0 0 3 3 3 0 DExH-box splicing factor binding site Ecm33 PF12454.3 KXX81936.1 - 8.2e-16 57.6 0.6 1.7e-15 56.5 0.4 1.6 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 KXX81936.1 - 5.8e-06 26.2 0.8 0.16 11.9 0.0 3.8 2 1 2 4 4 4 4 Receptor L domain HABP4_PAI-RBP1 PF04774.10 KXX81937.1 - 0.00032 21.1 2.1 0.00058 20.3 1.5 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CIAPIN1 PF05093.8 KXX81938.1 - 3.2e-35 120.2 4.5 4.7e-35 119.6 3.1 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Med15 PF09606.5 KXX81939.1 - 0.0018 16.6 34.0 0.0025 16.1 23.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 KXX81939.1 - 0.023 14.7 18.3 0.058 13.4 12.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 KXX81939.1 - 0.086 11.2 4.0 0.1 11.0 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endostatin PF06482.6 KXX81939.1 - 0.23 10.7 7.2 0.52 9.6 5.0 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EIIBC-GUT_N PF03612.9 KXX81939.1 - 2 8.0 4.9 4.7 6.7 3.4 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Med1 PF10744.4 KXX81940.1 - 2.6e-38 131.8 0.0 8e-38 130.2 0.0 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 KXX81941.1 - 8.8e-46 156.1 0.0 9.1e-42 142.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX81941.1 - 3.3e-22 78.8 0.0 8.2e-22 77.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX81941.1 - 0.0013 17.7 0.0 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KXX81941.1 - 0.061 13.0 0.1 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pex19 PF04614.7 KXX81942.1 - 1.9e-74 250.4 15.2 2.8e-74 249.8 10.6 1.2 1 0 0 1 1 1 1 Pex19 protein family Gluconate_2-dh3 PF13618.1 KXX81942.1 - 1 9.4 8.6 5 7.2 2.5 2.8 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF737 PF05300.6 KXX81942.1 - 6.9 6.5 10.6 44 3.9 6.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Ank_2 PF12796.2 KXX81944.1 - 1e-37 128.3 0.0 1.8e-15 57.0 0.0 4.0 3 1 1 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX81944.1 - 2.3e-31 106.0 0.0 1.5e-06 27.6 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KXX81944.1 - 3.1e-23 81.2 0.1 4.6e-09 36.2 0.0 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX81944.1 - 1.4e-21 76.4 0.0 3.3e-06 27.4 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX81944.1 - 6.1e-21 72.4 0.0 3.8e-05 23.5 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.7 KXX81944.1 - 2.3e-10 40.4 0.1 2.4e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX81944.1 - 3.2e-07 30.5 0.0 1.6e-06 28.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX81944.1 - 0.00027 21.0 0.0 0.0072 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KXX81944.1 - 0.0016 18.5 0.0 0.013 15.6 0.0 2.5 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 KXX81944.1 - 0.03 13.7 0.0 0.58 9.5 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain FAM196 PF15265.1 KXX81944.1 - 0.052 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 FAM196 family AAA_14 PF13173.1 KXX81944.1 - 0.12 12.2 0.2 0.41 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 KXX81945.1 - 7.8e-71 231.6 11.6 2.3e-10 39.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KXX81945.1 - 1.5e-08 33.2 1.2 0.00095 17.4 0.0 4.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Formyl_trans_N PF00551.14 KXX81946.1 - 1.7e-24 86.3 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase DUF4646 PF15496.1 KXX81947.1 - 3.4e-05 23.8 0.2 0.003 17.5 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 KXX81947.1 - 0.00097 18.5 22.2 0.00097 18.5 15.4 2.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 KXX81947.1 - 0.0021 16.4 0.0 0.0071 14.6 0.0 1.9 1 1 0 1 1 1 1 Transmembrane protein Acetyltransf_1 PF00583.19 KXX81948.1 - 1.4e-14 53.8 0.1 2.4e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KXX81948.1 - 1.7e-06 27.7 0.1 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KXX81948.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX81948.1 - 0.0066 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX81948.1 - 0.024 14.4 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CI-B14_5a PF07347.7 KXX81949.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.16 KXX81950.1 - 6e-23 80.8 0.0 9.2e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KXX81950.1 - 5.8e-16 58.3 0.0 8.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KXX81950.1 - 0.00028 20.7 0.0 0.00064 19.6 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme TT_ORF2 PF02957.10 KXX81950.1 - 6.1 7.5 15.0 0.55 10.9 0.7 2.3 2 0 0 2 2 2 0 TT viral ORF2 adh_short PF00106.20 KXX81951.1 - 5.3e-30 104.5 0.1 1.7e-29 102.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX81951.1 - 3.4e-22 79.3 0.2 1.9e-21 76.9 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX81951.1 - 1.5e-12 47.5 0.1 3e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX81951.1 - 5.9e-07 29.1 0.1 2.5e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KXX81951.1 - 0.073 13.1 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF164 PF02591.10 KXX81951.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Yae1_N PF09811.4 KXX81952.1 - 1.6e-09 37.1 7.2 2.9e-09 36.3 5.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Trns_repr_metal PF02583.12 KXX81952.1 - 0.21 11.7 2.2 0.34 11.1 1.0 1.7 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor Anp1 PF03452.9 KXX81953.1 - 1.4e-109 365.4 0.0 1.7e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.20 KXX81954.1 - 8.3e-16 58.2 0.0 1.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Mito_carr PF00153.22 KXX81955.1 - 1.4e-67 223.4 0.0 1.8e-24 85.2 0.1 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein SARA PF11409.3 KXX81955.1 - 0.048 13.5 0.6 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) UCR_14kD PF02271.11 KXX81956.1 - 7.4e-46 154.2 0.3 8.5e-46 154.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MIR PF02815.14 KXX81956.1 - 0.059 12.9 0.0 0.069 12.6 0.0 1.0 1 0 0 1 1 1 0 MIR domain DnaJ PF00226.26 KXX81957.1 - 6.2e-27 93.1 3.8 9.9e-27 92.4 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KXX81957.1 - 1.2e-14 53.9 0.0 1.9e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KXX81957.1 - 6.3e-14 51.7 17.8 1.1e-13 51.0 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF1311 PF07007.7 KXX81957.1 - 0.12 12.4 0.2 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) HypA PF01155.14 KXX81957.1 - 0.18 11.4 8.9 1.5 8.5 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KXX81957.1 - 5 7.0 11.6 86 3.0 8.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon RNA_Me_trans PF04252.8 KXX81958.1 - 2.4e-47 160.9 0.0 2.7e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 KXX81959.1 - 6.9e-113 377.9 0.0 1e-112 377.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KXX81959.1 - 0.0019 18.1 0.0 0.0096 15.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family RCR PF12273.3 KXX81959.1 - 0.085 13.4 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DHquinase_I PF01487.10 KXX81960.1 - 3.6e-58 196.8 0.0 5e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase GidB PF02527.10 KXX81960.1 - 0.0039 16.3 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DHO_dh PF01180.16 KXX81961.1 - 8.4e-18 64.3 0.0 1.5e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase LRR_6 PF13516.1 KXX81962.1 - 0.0007 19.4 8.8 1.2e+02 3.2 0.0 8.4 9 0 0 9 9 9 0 Leucine Rich repeat OmpH PF03938.9 KXX81962.1 - 0.00088 19.2 2.0 0.0026 17.7 1.4 1.8 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) LRR_4 PF12799.2 KXX81962.1 - 0.025 14.2 1.7 3.8 7.2 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_L18p PF00861.17 KXX81963.1 - 6.5e-43 145.7 1.3 1.3e-42 144.7 0.0 2.1 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KXX81963.1 - 1.3e-32 112.1 7.5 1.3e-32 112.1 5.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4297 PF14130.1 KXX81963.1 - 0.011 15.6 0.8 0.017 15.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) HAD_2 PF13419.1 KXX81964.1 - 4.2e-15 56.4 0.0 2.5e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX81964.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like zf-UBR PF02207.15 KXX81965.1 - 2.2e-16 59.2 4.4 2.2e-16 59.2 3.0 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ATG2_CAD PF13329.1 KXX81966.1 - 1.7e-46 157.6 0.0 4.1e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KXX81966.1 - 7e-29 99.8 0.3 7e-29 99.8 0.2 3.0 3 0 0 3 3 3 1 ATG C terminal domain Phage_attach PF05354.6 KXX81966.1 - 0.001 18.5 0.1 0.54 9.8 0.0 3.4 3 0 0 3 3 3 1 Phage Head-Tail Attachment Chorein_N PF12624.2 KXX81966.1 - 0.0033 16.9 0.1 0.082 12.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Presenilin PF01080.12 KXX81966.1 - 8.2 5.1 3.6 2.4 6.8 0.0 1.8 2 0 0 2 2 2 0 Presenilin Amino_oxidase PF01593.19 KXX81967.1 - 1.5e-48 166.0 1.7 3.8e-46 158.0 1.2 2.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX81967.1 - 1.8e-15 56.6 0.1 3.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX81967.1 - 7.2e-08 32.3 0.3 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KXX81967.1 - 1.6e-06 27.3 0.0 0.00026 19.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX81967.1 - 5.2e-06 26.6 0.1 0.00073 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX81967.1 - 2.3e-05 23.0 0.1 0.0014 17.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KXX81967.1 - 4.6e-05 23.7 0.2 0.00013 22.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX81967.1 - 0.00037 20.4 0.0 0.0054 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX81967.1 - 0.0007 18.5 0.1 0.0018 17.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KXX81967.1 - 0.00097 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KXX81967.1 - 0.0027 16.8 0.1 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KXX81967.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KXX81967.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX81967.1 - 0.06 12.2 0.3 0.67 8.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KXX81967.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KXX81967.1 - 0.2 11.6 0.2 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding GIDA PF01134.17 KXX81967.1 - 0.2 10.4 0.1 0.54 9.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Acyl-CoA_dh_1 PF00441.19 KXX81968.1 - 8.1e-34 116.8 0.9 1.2e-33 116.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KXX81968.1 - 3.5e-20 71.5 0.1 7.8e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KXX81968.1 - 7.2e-16 57.4 0.5 1.4e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KXX81968.1 - 6.3e-05 23.5 0.1 0.00049 20.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX81968.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.18 KXX81969.1 - 4.5e-47 155.8 54.1 6.5e-09 35.2 2.4 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KXX81969.1 - 9.6e-11 41.1 37.4 0.0093 15.6 0.7 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 KXX81969.1 - 4e-09 36.0 35.0 0.11 12.2 0.7 6.2 3 2 3 6 6 6 6 Zinc knuckle zf-CCHC_6 PF15288.1 KXX81969.1 - 0.001 18.6 42.5 0.035 13.7 0.5 6.2 5 2 2 7 7 7 4 Zinc knuckle RMF PF04957.7 KXX81969.1 - 0.22 11.2 11.4 1.5 8.5 0.4 3.6 3 1 1 4 4 4 0 Ribosome modulation factor zf-CCHC_2 PF13696.1 KXX81969.1 - 0.84 9.1 45.6 0.22 11.0 0.2 6.9 3 2 4 7 7 7 0 Zinc knuckle WXG100 PF06013.7 KXX81970.1 - 0.0016 18.4 2.2 0.0079 16.1 0.7 2.3 2 0 0 2 2 2 1 Proteins of 100 residues with WXG GAS PF13851.1 KXX81970.1 - 0.0036 16.5 1.6 0.16 11.1 0.1 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Laminin_I PF06008.9 KXX81970.1 - 0.006 15.9 2.0 0.23 10.7 0.1 2.2 2 0 0 2 2 2 1 Laminin Domain I DUF972 PF06156.8 KXX81970.1 - 0.0075 16.6 0.9 0.37 11.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DUF1311 PF07007.7 KXX81970.1 - 0.015 15.3 3.4 0.015 15.3 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) ATG16 PF08614.6 KXX81970.1 - 0.037 13.8 5.8 1.6 8.4 0.2 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Vps51 PF08700.6 KXX81970.1 - 0.038 13.8 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Vps51/Vps67 CENP-F_leu_zip PF10473.4 KXX81970.1 - 0.058 13.2 2.0 7.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KXX81970.1 - 0.11 12.0 4.0 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 IncA protein HALZ PF02183.13 KXX81970.1 - 1.2 8.8 9.1 1.6 8.4 0.2 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper FUSC PF04632.7 KXX81970.1 - 1.8 6.8 10.3 3.3 6.0 7.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 KXX81970.1 - 8.8 6.2 9.8 3.7 7.4 1.2 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Trp_syntA PF00290.15 KXX81971.1 - 7.6e-95 316.3 0.0 3e-94 314.3 0.0 1.8 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 KXX81971.1 - 6.2e-43 147.1 0.5 1.1e-42 146.3 0.4 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YbaJ PF10757.4 KXX81972.1 - 0.044 13.9 2.1 0.98 9.5 0.1 3.3 3 1 1 4 4 4 0 Biofilm formation regulator YbaJ GFA PF04828.9 KXX81973.1 - 4.3e-15 55.4 0.2 6.6e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DEAD PF00270.24 KXX81974.1 - 9.9e-44 148.7 0.1 3.6e-43 146.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KXX81974.1 - 3.5e-22 77.6 0.1 9.5e-22 76.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KXX81974.1 - 1.1e-20 73.2 0.0 3.6e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX81974.1 - 0.32 10.8 5.5 0.68 9.7 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit 6PF2K PF01591.13 KXX81975.1 - 1.8e-77 259.3 0.0 2.4e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KXX81975.1 - 3.3e-31 108.5 0.0 6.7e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KXX81975.1 - 6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX81975.1 - 0.0038 18.0 0.1 0.057 14.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KXX81975.1 - 0.0046 16.1 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Methyltransf_26 PF13659.1 KXX81975.1 - 0.069 13.1 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Zeta_toxin PF06414.7 KXX81975.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin MRP-S28 PF10213.4 KXX81976.1 - 3e-48 163.0 0.3 1.1e-47 161.2 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Aldedh PF00171.17 KXX81977.1 - 8.7e-83 278.1 0.0 1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YxiJ PF14176.1 KXX81977.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 YxiJ-like protein ECR1_N PF14382.1 KXX81978.1 - 1.5e-11 43.3 0.0 3.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KXX81978.1 - 0.0026 17.6 0.1 0.016 15.1 0.0 2.1 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 KXX81978.1 - 0.0059 16.6 2.2 1.3 9.2 0.0 3.5 4 0 0 4 4 4 2 S1 RNA binding domain HET PF06985.6 KXX81980.1 - 7.5e-20 71.5 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 KXX81981.1 - 2.9e-46 153.7 29.3 6.5e-08 32.1 0.1 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat PD40 PF07676.7 KXX81981.1 - 0.027 14.1 0.0 2.4 7.9 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KXX81981.1 - 0.033 12.3 0.8 0.44 8.6 0.1 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Glyco_tran_28_C PF04101.11 KXX81982.1 - 2.7e-17 62.9 0.7 4.8e-16 58.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ECH PF00378.15 KXX81982.1 - 0.0044 16.1 0.1 0.0067 15.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HCV_NS5a_C PF12941.2 KXX81982.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF3043 PF11241.3 KXX81982.1 - 0.14 11.7 3.4 0.21 11.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HET PF06985.6 KXX81983.1 - 1.6e-18 67.1 9.0 6.2e-16 58.8 1.7 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.8 KXX81986.1 - 1.9e-21 76.6 0.1 2.5e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KXX81986.1 - 1.7e-18 66.4 0.0 3.5e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) NYAP_N PF15439.1 KXX81987.1 - 0.0091 15.2 4.7 0.014 14.6 3.2 1.3 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Apolipoprotein PF01442.13 KXX81987.1 - 0.089 12.2 12.2 0.79 9.1 6.0 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAUS4 PF14735.1 KXX81987.1 - 0.17 11.1 4.9 0.18 11.0 1.3 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 4 TBCA PF02970.11 KXX81987.1 - 3.6 7.7 7.7 7.3 6.7 0.1 3.4 3 2 2 5 5 5 0 Tubulin binding cofactor A FlgN PF05130.7 KXX81987.1 - 9.8 6.4 12.0 19 5.5 7.5 2.2 2 1 0 2 2 2 0 FlgN protein Ribosomal_L28 PF00830.14 KXX81988.1 - 4.4e-22 77.6 0.8 6.6e-22 77.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L28 family NAD_binding_10 PF13460.1 KXX81989.1 - 1.3e-12 48.1 0.2 1.7e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX81989.1 - 2.9e-09 36.5 0.1 4.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KXX81989.1 - 0.00097 18.6 0.0 0.0027 17.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KXX81989.1 - 0.013 15.4 1.0 0.059 13.2 0.4 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Peripla_BP_4 PF13407.1 KXX81989.1 - 0.018 14.3 1.5 0.075 12.3 0.3 2.3 2 1 1 3 3 3 0 Periplasmic binding protein domain FAD_binding_2 PF00890.19 KXX81989.1 - 0.035 12.9 2.2 0.068 11.9 1.5 1.9 1 1 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.1 KXX81989.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HEM4 PF02602.10 KXX81989.1 - 0.088 12.0 0.7 2.3 7.3 0.0 2.4 1 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Phytase-like PF13449.1 KXX81990.1 - 1.5e-30 106.5 0.3 3e-30 105.6 0.2 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase PLDc PF00614.17 KXX81991.1 - 1.1e-16 59.9 1.1 2.6e-08 33.3 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KXX81991.1 - 5e-12 45.6 0.1 1.7e-07 30.9 0.0 2.9 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KXX81991.1 - 4.8e-07 29.5 0.4 3.7e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 PX domain COQ7 PF03232.8 KXX81992.1 - 1e-63 213.8 0.0 1.3e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KXX81992.1 - 0.00026 21.3 0.0 0.00043 20.6 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin Vitellogenin_N PF01347.17 KXX81992.1 - 0.15 10.2 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Oxidored_q6 PF01058.17 KXX81993.1 - 2.9e-22 78.6 0.0 4e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tubulin PF00091.20 KXX81994.1 - 3.7e-73 245.9 0.0 5.1e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KXX81994.1 - 8.1e-46 155.1 0.4 1.6e-45 154.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KXX81994.1 - 5.7e-08 32.8 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KXX81994.1 - 0.087 12.2 0.0 0.27 10.6 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain SPX PF03105.14 KXX81995.1 - 6.4e-22 78.6 2.3 2.6e-12 47.1 0.1 3.1 1 1 2 3 3 3 2 SPX domain CcmD PF04995.9 KXX81995.1 - 0.007 16.0 5.3 0.012 15.3 0.1 3.0 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) Orbi_NS3 PF01616.11 KXX81995.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Orbivirus NS3 ABC2_membrane_3 PF12698.2 KXX81995.1 - 0.17 10.8 0.7 0.46 9.4 0.2 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Mpp10 PF04006.7 KXX81996.1 - 5.4e-86 289.2 77.0 4e-79 266.5 20.9 2.2 1 1 1 2 2 2 2 Mpp10 protein Amidohydro_3 PF07969.6 KXX81997.1 - 1.7e-57 195.4 0.4 2.1e-57 195.1 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KXX81997.1 - 0.00015 21.5 0.0 0.0031 17.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KXX81997.1 - 0.0036 17.3 0.7 2.9 7.8 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KXX81997.1 - 0.005 16.6 0.1 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase NMO PF03060.10 KXX81998.1 - 3.3e-42 144.8 13.6 1.1e-40 139.7 9.4 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KXX81998.1 - 4e-06 25.9 13.1 7.3e-06 25.0 8.4 1.7 1 1 1 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KXX81998.1 - 1.1e-05 24.5 8.8 0.00017 20.6 6.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KXX81998.1 - 0.0037 16.2 5.3 0.0063 15.4 3.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KXX81998.1 - 0.28 10.2 3.3 0.55 9.2 1.8 1.9 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG RRM_1 PF00076.17 KXX81999.1 - 9e-17 60.4 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX81999.1 - 1e-16 60.6 0.3 2.1e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX81999.1 - 2.2e-07 30.5 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 KXX81999.1 - 0.0025 15.7 0.9 0.003 15.5 0.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG6 PF04111.7 KXX81999.1 - 0.11 11.5 2.6 0.13 11.3 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 KXX81999.1 - 0.18 11.7 4.1 0.25 11.2 2.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KXX81999.1 - 0.42 10.1 4.2 0.65 9.5 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KXX81999.1 - 0.57 9.7 3.0 0.68 9.4 2.0 1.1 1 0 0 1 1 1 0 IncA protein GRP PF07172.6 KXX81999.1 - 6.9 7.2 18.7 0.16 12.4 8.2 1.8 2 1 0 2 2 2 0 Glycine rich protein family HECT PF00632.20 KXX82000.1 - 5.6e-92 308.2 0.0 8.3e-92 307.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KXX82000.1 - 5e-33 112.5 20.9 4.9e-11 42.2 4.0 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KXX82000.1 - 3.1e-16 58.9 0.1 9.5e-16 57.4 0.1 1.9 1 0 0 1 1 1 1 C2 domain DUF829 PF05705.9 KXX82001.1 - 2.1e-42 145.5 0.0 2.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box PF00646.28 KXX82003.1 - 5.5e-08 32.2 0.1 4.1e-07 29.4 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KXX82003.1 - 3.4e-05 23.4 0.2 9e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KXX82004.1 - 1.2e-28 99.8 31.6 1.2e-28 99.8 21.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PDGLE PF13190.1 KXX82004.1 - 0.058 13.0 0.6 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 PDGLE domain Aminotran_1_2 PF00155.16 KXX82005.1 - 1.2e-93 313.9 0.0 1.4e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M13_N PF05649.8 KXX82006.1 - 1.1e-93 314.4 0.0 1.4e-93 314.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KXX82006.1 - 1.1e-55 188.0 0.0 1.9e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 AAA_16 PF13191.1 KXX82007.1 - 0.018 15.0 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain CBM_20 PF00686.14 KXX82008.1 - 2.3e-33 113.6 0.2 3.8e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KXX82008.1 - 6.4e-09 36.3 0.3 2.1e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Chitin binding domain Cellulase PF00150.13 KXX82009.1 - 6e-17 61.7 8.5 1.2e-16 60.8 5.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KXX82009.1 - 5.5e-06 25.5 0.0 4.2e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KXX82009.1 - 1.8e-05 25.0 0.0 5.6e-05 23.4 0.0 1.9 1 1 1 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KXX82009.1 - 0.0002 20.6 0.7 0.00082 18.5 0.1 2.3 2 1 0 2 2 2 1 Beta-galactosidase DUF4434 PF14488.1 KXX82009.1 - 0.0011 18.7 0.1 0.21 11.3 0.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4434) Glyco_hydro_10 PF00331.15 KXX82009.1 - 0.032 13.2 0.2 0.08 11.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 FAD_binding_4 PF01565.18 KXX82011.1 - 8.6e-19 67.3 1.7 1.6e-18 66.4 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KXX82011.1 - 3.9e-12 45.5 32.7 1.6e-07 30.4 19.0 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily BBE PF08031.7 KXX82011.1 - 3.3e-09 36.5 0.2 6.8e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like CCDC155 PF14662.1 KXX82012.1 - 0.036 13.6 0.2 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 OSTMP1 PF09777.4 KXX82012.1 - 0.15 11.1 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor F-box-like PF12937.2 KXX82014.1 - 0.036 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like Tctex-1 PF03645.8 KXX82015.1 - 2.9e-34 116.9 0.0 3.4e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family KH_1 PF00013.24 KXX82016.1 - 6.2e-44 147.4 11.6 1.6e-15 56.4 0.7 3.6 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KXX82016.1 - 4.9e-30 102.6 16.7 4.4e-11 42.1 1.0 4.3 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KXX82016.1 - 5.6e-13 48.2 1.7 0.0058 16.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KXX82016.1 - 1.3e-09 37.5 2.6 0.088 12.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KXX82016.1 - 0.0004 20.1 2.4 0.34 10.7 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain CTP_transf_2 PF01467.21 KXX82017.1 - 1.2e-22 80.6 0.0 2.2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase DUF4611 PF15387.1 KXX82017.1 - 7.6 6.7 8.3 11 6.1 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 KXX82018.1 - 0.26 9.1 4.8 0.35 8.7 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Plus-3 PF03126.13 KXX82019.1 - 1.7e-22 79.4 0.1 5.5e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain DUF202 PF02656.10 KXX82020.1 - 2.4e-13 50.0 5.3 3.1e-13 49.7 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 KXX82020.1 - 0.075 12.6 7.1 0.098 12.2 4.9 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF983 PF06170.7 KXX82020.1 - 0.12 12.4 1.3 10 6.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DUF4131 PF13567.1 KXX82020.1 - 5.8 6.2 6.8 11 5.3 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Alba PF01918.16 KXX82021.1 - 1.2e-06 28.0 0.0 2.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Alba zf-H2C2_2 PF13465.1 KXX82022.1 - 1.5e-14 53.4 7.8 5.3e-08 32.7 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KXX82022.1 - 4.3e-12 45.6 11.8 8.6e-06 25.8 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX82022.1 - 3.1e-11 42.7 11.3 3.2e-05 23.9 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX82022.1 - 7.5e-07 29.1 2.0 0.074 13.2 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX82022.1 - 2.9e-05 24.1 1.4 0.0099 16.0 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KXX82022.1 - 0.07 13.2 1.6 0.13 12.4 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.1 KXX82022.1 - 0.11 12.7 0.6 0.24 11.6 0.4 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 KXX82022.1 - 0.31 11.0 7.9 4.7 7.2 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 KXX82022.1 - 0.46 10.5 3.4 3.9 7.6 2.5 2.2 1 1 1 2 2 2 0 LIM domain Aminotran_1_2 PF00155.16 KXX82023.1 - 1.2e-62 211.9 0.0 2.8e-42 144.9 0.0 2.3 2 1 1 3 3 3 2 Aminotransferase class I and II Nop52 PF05997.7 KXX82024.1 - 4.3e-45 153.7 0.0 4e-40 137.5 0.0 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 KXX82024.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Syntaxin-18_N PF10496.4 KXX82025.1 - 3.5e-14 52.3 0.0 1.2e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus MFS_1 PF07690.11 KXX82026.1 - 1.4e-46 158.8 21.3 1.4e-46 158.8 14.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82026.1 - 6.6e-09 34.8 11.0 6.6e-09 34.8 7.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KXX82026.1 - 0.005 16.5 1.0 0.081 12.7 0.3 3.0 2 1 0 2 2 2 1 MFS_1 like family DUF1422 PF07226.6 KXX82026.1 - 0.32 10.7 4.0 0.75 9.5 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1422) Thyroglobulin_1 PF00086.13 KXX82028.1 - 0.094 12.0 0.1 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat APH PF01636.18 KXX82029.1 - 0.00092 19.0 0.3 0.00092 19.0 0.2 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 KXX82029.1 - 0.13 11.3 0.0 0.32 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain SAPS PF04499.10 KXX82029.1 - 0.9 8.0 6.3 1.4 7.4 4.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ARGLU PF15346.1 KXX82029.1 - 2.8 7.6 42.8 6.1 6.6 29.7 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF3659 PF12396.3 KXX82030.1 - 2.4e-15 55.9 2.4 2.2e-10 40.0 0.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) ORC6 PF05460.8 KXX82030.1 - 0.29 10.2 5.0 0.39 9.7 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ctr PF04145.10 KXX82032.1 - 7e-33 113.7 10.7 4.1e-32 111.2 7.4 1.8 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.23 KXX82033.1 - 7.9e-13 48.2 0.0 1.9e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain SelB-wing_3 PF09107.6 KXX82033.1 - 0.067 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix FAA_hydrolase PF01557.13 KXX82034.1 - 1e-50 172.2 0.0 1.3e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 KXX82035.1 - 5.5e-55 184.9 0.1 7.5e-45 152.0 0.0 2.0 1 1 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KXX82035.1 - 2.5e-05 23.6 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KXX82035.1 - 0.0022 17.7 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KXX82035.1 - 0.04 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin ARD PF03079.9 KXX82035.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family RRN7 PF11781.3 KXX82035.1 - 0.11 11.9 0.3 0.11 11.9 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_S27 PF01599.14 KXX82035.1 - 1.9 8.3 5.7 5.9 6.8 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S27a EXS PF03124.9 KXX82037.1 - 2.6e-99 332.5 4.7 2.9e-99 332.3 3.3 1.0 1 0 0 1 1 1 1 EXS family ADH_zinc_N PF00107.21 KXX82038.1 - 6.3e-09 35.4 0.0 2.7e-08 33.4 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX82038.1 - 5.8e-06 26.0 1.0 0.00015 21.4 0.7 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NARP1 PF12569.3 KXX82039.1 - 2.4e-207 689.7 16.6 1.6e-204 680.4 6.0 2.3 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 KXX82039.1 - 3.4e-25 88.0 35.6 1e-05 26.0 5.9 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KXX82039.1 - 2.9e-20 72.3 28.3 4.2e-05 23.8 0.1 7.7 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 KXX82039.1 - 1.4e-19 69.5 35.7 3.5e-06 26.5 0.1 7.8 8 1 0 8 8 8 5 TPR repeat TPR_14 PF13428.1 KXX82039.1 - 6.6e-15 54.2 34.4 0.0012 19.2 0.0 11.0 9 3 4 13 13 11 3 Tetratricopeptide repeat TPR_2 PF07719.12 KXX82039.1 - 1.2e-11 43.6 46.6 0.00057 19.6 0.1 11.1 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_17 PF13431.1 KXX82039.1 - 2.3e-11 42.9 22.5 0.0014 18.6 0.0 9.1 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KXX82039.1 - 3.6e-11 42.7 15.9 0.00029 20.6 0.0 7.3 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX82039.1 - 7.3e-10 38.6 23.2 0.0056 16.5 0.1 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KXX82039.1 - 1.2e-08 34.1 35.4 1.8e-05 24.1 0.1 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KXX82039.1 - 1.5e-06 27.5 16.6 0.003 17.2 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KXX82039.1 - 1.3e-05 24.9 4.3 2 8.3 0.1 5.2 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 KXX82039.1 - 0.00025 20.7 0.7 0.51 10.1 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KXX82039.1 - 0.00051 19.6 14.6 4.5 7.3 0.0 7.6 7 1 1 8 8 7 1 Tetratricopeptide repeat BTAD PF03704.12 KXX82039.1 - 0.013 15.8 2.8 0.013 15.8 2.0 3.3 3 1 1 4 4 3 0 Bacterial transcriptional activator domain PPTA PF01239.17 KXX82039.1 - 0.015 14.6 0.5 4 6.9 0.0 3.6 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.1 KXX82039.1 - 0.031 14.1 22.4 0.21 11.5 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat DAGK_cat PF00781.19 KXX82040.1 - 1.1e-27 96.0 0.0 1.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PgaD PF13994.1 KXX82044.1 - 0.0057 16.1 0.0 0.0061 16.0 0.0 1.0 1 0 0 1 1 1 1 PgaD-like protein TLC PF03219.9 KXX82044.1 - 0.015 13.7 0.0 0.016 13.7 0.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter UPF0560 PF10577.4 KXX82044.1 - 0.029 12.6 0.1 0.033 12.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Vpu PF00558.14 KXX82044.1 - 0.07 12.7 0.4 0.083 12.4 0.3 1.1 1 0 0 1 1 1 0 Vpu protein ATP-synt_8 PF00895.15 KXX82044.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 DUF912 PF06024.7 KXX82044.1 - 0.13 12.2 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_S5_C PF03719.10 KXX82045.1 - 5.3e-19 67.2 0.0 3.8e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KXX82045.1 - 7e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Rhabdo_ncap_2 PF03216.8 KXX82045.1 - 0.12 11.1 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein DASH_Dad3 PF08656.5 KXX82046.1 - 9.7e-23 79.6 0.5 3.4e-21 74.7 0.4 2.0 1 1 0 1 1 1 1 DASH complex subunit Dad3 DAG1 PF05454.6 KXX82046.1 - 0.038 13.1 0.4 0.041 13.0 0.3 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Cdc6_C PF09079.6 KXX82046.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal PARP PF00644.15 KXX82047.1 - 3.1e-11 43.1 0.0 5.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KXX82047.1 - 1.7e-08 33.9 0.0 3.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG5 PF10392.4 KXX82048.1 - 5.7e-05 23.0 2.2 0.0018 18.2 0.1 3.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Phage_pRha PF09669.5 KXX82048.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Ribosomal_60s PF00428.14 KXX82048.1 - 0.079 13.3 4.5 0.38 11.1 3.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATE_C PF04377.10 KXX82049.1 - 2.5e-43 147.1 0.0 4e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KXX82049.1 - 8.9e-16 57.4 1.7 1.6e-15 56.6 0.7 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KXX82049.1 - 0.069 13.1 0.2 0.069 13.1 0.1 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 KXX82050.1 - 1.2e-18 67.0 0.7 1.5e-18 66.7 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain 2-Hacid_dh_C PF02826.14 KXX82051.1 - 1e-56 190.9 0.0 1.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX82051.1 - 4.1e-20 71.6 0.0 6.2e-20 71.0 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KXX82051.1 - 4.9e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 KXX82052.1 - 9e-08 31.9 11.0 1.4e-07 31.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain JAB PF01398.16 KXX82053.1 - 3.1e-09 36.5 0.2 3e-08 33.4 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 KXX82053.1 - 0.19 10.9 1.5 1.8 7.7 0.3 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal AdoHcyase PF05221.12 KXX82054.1 - 2.5e-140 466.0 0.3 2.9e-140 465.8 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KXX82054.1 - 5.6e-83 276.6 2.7 9.9e-83 275.8 1.9 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KXX82054.1 - 2.7e-06 26.6 1.0 4e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TMEM107 PF14995.1 KXX82054.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein IlvN PF07991.7 KXX82054.1 - 0.029 13.7 0.2 0.055 12.8 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 KXX82054.1 - 0.037 13.5 0.5 0.084 12.4 0.4 1.8 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KXX82054.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain zf-LYAR PF08790.6 KXX82056.1 - 1.4e-14 53.4 2.4 3.4e-14 52.2 1.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Pex2_Pex12 PF04757.9 KXX82057.1 - 1.9e-48 164.8 3.4 2.5e-48 164.4 2.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KXX82057.1 - 1.2e-12 47.4 7.9 2e-12 46.7 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX82057.1 - 1e-11 44.6 7.7 1.7e-11 43.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX82057.1 - 6.3e-10 38.5 5.3 9.8e-10 37.9 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX82057.1 - 7e-10 38.4 6.1 1.2e-09 37.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX82057.1 - 8.2e-09 35.0 5.3 1.4e-08 34.3 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX82057.1 - 5.8e-07 29.2 7.6 9.9e-07 28.5 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KXX82057.1 - 4.5e-05 23.1 3.0 8.7e-05 22.2 2.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KXX82057.1 - 0.0001 22.3 7.1 0.00028 20.9 4.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KXX82057.1 - 0.00085 18.9 4.6 0.0018 17.9 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KXX82057.1 - 0.0061 16.0 1.1 0.011 15.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KXX82057.1 - 0.077 12.5 7.5 0.15 11.6 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KXX82057.1 - 0.13 12.0 2.4 0.26 11.1 1.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 KXX82057.1 - 2.1 8.2 7.4 5.8 6.8 5.1 1.7 1 1 0 1 1 1 0 IBR domain ABC_tran PF00005.22 KXX82058.1 - 5.3e-48 162.7 0.0 6e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX82058.1 - 9.3e-21 75.0 0.0 7.1e-08 32.7 0.0 4.5 5 0 0 5 5 4 3 AAA domain ABC2_membrane_3 PF12698.2 KXX82058.1 - 1.2e-16 60.7 44.1 1.1e-09 37.8 17.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein R3H PF01424.17 KXX82058.1 - 6.8e-15 54.5 0.6 1.1e-13 50.6 0.0 2.5 2 0 0 2 2 2 1 R3H domain SMC_N PF02463.14 KXX82058.1 - 3.8e-09 36.1 0.0 0.017 14.3 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KXX82058.1 - 1.1e-06 29.0 0.1 0.02 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX82058.1 - 6.5e-06 25.4 0.3 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KXX82058.1 - 1.1e-05 24.8 0.5 0.2 11.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain zf-NF-X1 PF01422.12 KXX82058.1 - 2.8e-05 23.9 15.1 2.8e-05 23.9 10.5 9.7 9 1 0 9 9 7 5 NF-X1 type zinc finger AAA_16 PF13191.1 KXX82058.1 - 5.8e-05 23.1 3.4 0.14 12.0 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 KXX82058.1 - 0.0009 18.8 0.3 1.4 8.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.17 KXX82058.1 - 0.018 14.5 0.6 2.6 7.4 0.1 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KXX82058.1 - 0.024 14.8 0.1 9 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KXX82058.1 - 0.03 13.3 0.0 21 4.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 KXX82058.1 - 0.05 13.3 4.9 0.19 11.5 0.0 3.6 4 0 0 4 4 2 0 Part of AAA domain AAA_14 PF13173.1 KXX82058.1 - 0.1 12.5 0.0 8.4 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KXX82058.1 - 0.1 11.6 0.2 6.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 KXX82058.1 - 0.13 12.1 5.2 6.1 6.8 0.0 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KXX82058.1 - 0.18 11.9 0.5 4.7 7.4 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KXX82058.1 - 0.23 10.1 0.1 6.7 5.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Thymidylate_kin PF02223.12 KXX82058.1 - 0.39 10.0 0.4 33 3.7 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Arf PF00025.16 KXX82058.1 - 0.54 9.4 0.2 16 4.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 KXX82058.1 - 0.6 9.7 0.2 2.2 7.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KXX82058.1 - 0.64 9.3 0.2 24 4.2 0.0 2.4 3 0 0 3 3 2 0 AAA-like domain AAA_13 PF13166.1 KXX82058.1 - 2 6.7 0.0 7.5 4.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.6 KXX82058.1 - 2.2 6.8 0.1 8 5.0 0.0 1.7 2 0 0 2 2 2 0 PrkA AAA domain Abhydrolase_5 PF12695.2 KXX82059.1 - 4.8e-24 84.7 0.0 8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82059.1 - 6.7e-20 71.9 0.1 9.5e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82059.1 - 1.5e-07 31.1 0.1 0.00032 20.3 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 KXX82059.1 - 1.9e-05 23.3 0.1 1.3 7.4 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 KXX82059.1 - 6.5e-05 22.4 0.0 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.7 KXX82059.1 - 0.00017 20.4 0.0 0.00024 19.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KXX82059.1 - 0.00038 19.9 0.0 0.084 12.3 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KXX82059.1 - 0.0017 17.5 0.0 0.012 14.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KXX82059.1 - 0.0038 16.8 0.0 0.0083 15.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX82059.1 - 0.0043 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KXX82059.1 - 0.0076 15.5 0.0 2.1 7.5 0.0 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 KXX82059.1 - 0.017 14.8 0.0 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 KXX82059.1 - 0.057 13.0 0.2 0.4 10.2 0.2 2.0 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S15 PF02129.13 KXX82059.1 - 0.12 11.7 0.0 5.2 6.4 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) p450 PF00067.17 KXX82060.1 - 5.8e-57 193.2 0.0 6.8e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 KXX82061.1 - 7.4e-14 51.3 11.2 1.6e-13 50.2 7.8 1.6 1 0 0 1 1 1 1 CFEM domain Zn_clus PF00172.13 KXX82062.1 - 3.7e-08 33.1 11.7 1.1e-07 31.6 8.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX82062.1 - 9.2e-07 27.7 0.3 1.5e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.12 KXX82063.1 - 8.6e-40 136.3 0.0 1e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 KXX82064.1 - 1.9e-45 155.1 52.6 1e-44 152.6 35.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX82064.1 - 1.3e-20 73.1 25.2 8.3e-20 70.5 17.5 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX82064.1 - 8.4e-11 41.0 13.1 8.4e-11 41.0 9.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MnhB PF04039.8 KXX82065.1 - 1.7 8.6 9.8 0.13 12.3 1.6 2.4 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF3659 PF12396.3 KXX82066.1 - 9.4e-107 348.7 45.4 9.9e-24 82.7 0.8 5.4 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) Colicin_immun PF09204.5 KXX82066.1 - 0.15 12.1 1.6 0.5 10.4 1.1 1.9 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity SNF2_N PF00176.18 KXX82067.1 - 4.5e-74 248.9 0.0 7.3e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KXX82067.1 - 2.1e-15 56.5 0.0 3.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KXX82067.1 - 1.3e-10 41.0 0.0 4.1e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KXX82067.1 - 1.2e-09 37.8 12.9 3.2e-09 36.4 9.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KXX82067.1 - 2.3e-08 33.5 15.2 5.7e-08 32.2 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX82067.1 - 1.1e-07 31.7 15.2 1.1e-07 31.7 10.5 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX82067.1 - 1.5e-07 30.9 11.4 3.7e-07 29.7 7.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KXX82067.1 - 4.4e-07 29.4 15.0 4.4e-07 29.4 10.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KXX82067.1 - 5.6e-06 26.1 12.7 1.2e-05 25.0 8.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 KXX82067.1 - 1.7e-05 24.3 0.0 5.4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-rbx1 PF12678.2 KXX82067.1 - 2.7e-05 24.1 6.1 7.8e-05 22.7 4.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KXX82067.1 - 0.0025 17.4 13.9 0.0025 17.4 9.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 KXX82067.1 - 0.0041 16.8 4.8 0.012 15.3 3.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein U-box PF04564.10 KXX82067.1 - 0.0066 16.3 0.2 0.024 14.6 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-Apc11 PF12861.2 KXX82067.1 - 0.0068 16.2 4.8 0.016 15.0 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 KXX82067.1 - 0.0084 15.5 0.5 4.1 6.9 0.0 3.0 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-RING_4 PF14570.1 KXX82067.1 - 0.0093 15.5 7.9 0.023 14.2 5.5 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KXX82067.1 - 0.079 12.4 14.6 0.074 12.5 7.7 2.5 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KXX82067.1 - 0.29 10.6 10.6 1.6 8.2 2.7 2.7 1 1 2 3 3 3 0 P-11 zinc finger DZR PF12773.2 KXX82067.1 - 1.1 9.0 5.2 3.7 7.4 3.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon Glyco_hydro_61 PF03443.9 KXX82068.1 - 3.2e-45 154.5 0.0 4.6e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.16 KXX82069.1 - 1.4e-27 95.4 0.0 1.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 KXX82070.1 - 7.5e-59 198.9 0.0 1.3e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82070.1 - 1.7e-21 76.4 0.0 3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX82070.1 - 0.0035 17.1 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 KXX82071.1 - 1.7e-26 91.4 0.2 2.6e-26 90.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KXX82071.1 - 2.4e-24 85.2 0.6 1.1e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 KXX82072.1 - 3.1e-131 437.2 0.0 3.8e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KXX82072.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Histone PF00125.19 KXX82073.1 - 5.9e-11 42.3 0.3 7.5e-11 41.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KXX82073.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF4095 PF13338.1 KXX82073.1 - 0.026 14.6 0.4 0.051 13.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) CBFD_NFYB_HMF PF00808.18 KXX82073.1 - 0.028 14.4 0.1 0.051 13.6 0.0 1.5 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho86 PF11124.3 KXX82074.1 - 0.0062 15.5 0.2 0.01 14.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 AOX PF01786.12 KXX82075.1 - 2.1e-87 291.8 0.0 2.6e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase HAUS-augmin3 PF14932.1 KXX82076.1 - 0.68 9.0 4.8 1.9 7.6 0.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HD PF01966.17 KXX82079.1 - 0.00014 21.9 0.2 0.00026 20.9 0.1 1.5 1 1 0 1 1 1 1 HD domain APH PF01636.18 KXX82081.1 - 6e-34 117.8 0.1 8.9e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KXX82081.1 - 0.023 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF2263 PF10021.4 KXX82082.1 - 2.7e-23 82.5 0.2 1.2e-20 74.0 0.1 2.4 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) AAA PF00004.24 KXX82083.1 - 4.6e-16 59.2 0.0 7.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX82083.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KXX82083.1 - 0.012 15.4 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KXX82083.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Abhydrolase_3 PF07859.8 KXX82084.1 - 1.8e-12 47.3 0.1 2.2e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 KXX82085.1 - 0.012 14.4 21.3 0.031 13.0 6.5 3.1 2 1 1 4 4 4 0 Major Facilitator Superfamily GLTP PF08718.6 KXX82086.1 - 3.2e-46 157.0 0.0 6.1e-46 156.1 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) RNase_H PF00075.19 KXX82087.1 - 8.7e-12 45.5 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 RNase H HET PF06985.6 KXX82088.1 - 0.029 14.5 1.1 0.065 13.3 0.8 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Sec39 PF08314.6 KXX82088.1 - 0.12 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 DUF4395 PF14340.1 KXX82089.1 - 0.032 14.3 1.1 0.032 14.3 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) PLDc PF00614.17 KXX82091.1 - 1.8e-15 56.1 2.0 1.2e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KXX82091.1 - 1.1e-12 47.7 0.0 3.5e-05 23.5 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain NMO PF03060.10 KXX82095.1 - 7.1e-73 245.6 0.2 1e-72 245.0 0.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KXX82095.1 - 1.1e-08 34.3 0.0 2.7e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX82095.1 - 2.4e-06 26.6 1.3 3.5e-06 26.1 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KXX82095.1 - 0.0028 16.6 0.1 0.0052 15.7 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.9 KXX82095.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.16 KXX82095.1 - 0.069 12.1 0.1 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pterin_bind PF00809.17 KXX82096.1 - 2.1e-62 210.2 0.0 3.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KXX82096.1 - 2.7e-39 133.8 0.0 8.3e-39 132.2 0.0 1.8 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.1 KXX82096.1 - 0.035 13.3 0.9 0.1 11.7 0.6 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase MscL PF01741.13 KXX82097.1 - 8.1e-15 55.1 0.3 1.9e-14 53.8 0.2 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 KXX82097.1 - 0.00079 19.1 1.7 0.0013 18.4 1.2 1.4 1 0 0 1 1 1 1 BED zinc finger PBP1_TM PF14812.1 KXX82097.1 - 0.037 14.3 5.2 0.062 13.6 3.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stc1 PF12898.2 KXX82097.1 - 0.042 13.9 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 Stc1 domain C1_1 PF00130.17 KXX82097.1 - 0.076 12.7 1.6 0.12 12.1 1.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bd3614_N PF14442.1 KXX82097.1 - 3.5 7.5 6.6 7.1 6.6 4.6 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Cwf_Cwc_15 PF04889.7 KXX82097.1 - 6.6 6.3 6.2 9.3 5.8 4.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUR7 PF06687.7 KXX82098.1 - 1.2e-14 54.3 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family MGC-24 PF05283.6 KXX82100.1 - 5.5 6.7 10.7 9.8 5.9 7.4 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) MFS_1 PF07690.11 KXX82101.1 - 3.4e-36 124.6 36.9 3.4e-36 124.6 25.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily GDPD PF03009.12 KXX82102.1 - 2.1e-14 53.6 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.23 KXX82102.1 - 5.5e-11 43.0 0.1 4.3e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KXX82102.1 - 0.025 14.2 0.1 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 KXX82102.1 - 0.1 12.5 0.9 0.39 10.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 KXX82103.1 - 2.9e-19 68.9 0.4 2.9e-19 68.9 0.3 3.8 4 1 1 5 5 5 1 FAD binding domain BBE PF08031.7 KXX82103.1 - 2.7e-11 43.2 0.5 5.1e-11 42.2 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Esterase PF00756.15 KXX82104.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ABC_tran PF00005.22 KXX82105.1 - 1.2e-45 155.1 0.0 4.8e-24 85.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KXX82105.1 - 3.6e-24 85.6 24.4 5.1e-22 78.5 6.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KXX82105.1 - 6.3e-10 38.6 4.0 0.018 14.2 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX82105.1 - 3.4e-08 32.8 1.1 0.003 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KXX82105.1 - 5e-08 33.2 0.9 0.0085 16.0 0.0 3.5 3 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 KXX82105.1 - 4.9e-06 27.0 0.1 0.012 15.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX82105.1 - 1.4e-05 25.1 0.0 0.028 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KXX82105.1 - 4.7e-05 23.5 0.1 0.24 11.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KXX82105.1 - 8.6e-05 22.4 0.6 0.38 10.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_19 PF13245.1 KXX82105.1 - 0.00024 20.7 0.2 0.049 13.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KXX82105.1 - 0.00032 20.2 0.7 0.017 14.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KXX82105.1 - 0.00066 18.8 0.2 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 KXX82105.1 - 0.00088 18.4 0.2 0.19 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KXX82105.1 - 0.0012 19.6 0.4 1.9 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX82105.1 - 0.0012 18.2 0.1 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KXX82105.1 - 0.0018 18.1 1.5 0.085 12.6 0.1 2.3 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 KXX82105.1 - 0.002 17.1 0.4 0.71 8.7 0.0 2.5 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 KXX82105.1 - 0.003 17.8 0.2 3 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 KXX82105.1 - 0.0055 15.8 0.7 1 8.4 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 KXX82105.1 - 0.015 15.8 0.3 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 KXX82105.1 - 0.015 15.0 4.4 0.027 14.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 KXX82105.1 - 0.017 14.6 0.2 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KXX82105.1 - 0.021 14.2 0.2 1.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain MobB PF03205.9 KXX82105.1 - 0.027 14.1 0.6 1.7 8.3 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KXX82105.1 - 0.053 13.0 1.5 3.3 7.1 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KXX82105.1 - 0.078 12.3 1.6 7.6 5.8 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 KXX82105.1 - 0.08 11.8 0.3 3.5 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.24 KXX82105.1 - 0.092 12.2 0.8 8 5.9 0.3 3.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 KXX82105.1 - 0.15 10.9 1.3 1 8.1 0.0 2.7 3 1 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.1 KXX82105.1 - 0.16 11.8 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KXX82105.1 - 0.18 11.4 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KXX82105.1 - 0.18 12.0 0.1 14 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.1 KXX82105.1 - 0.21 11.1 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KXX82105.1 - 0.44 9.4 0.0 2.3 7.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KXX82105.1 - 1.1 8.8 5.7 11 5.6 0.0 3.2 3 0 0 3 3 3 0 NTPase VAD1-2 PF15310.1 KXX82105.1 - 1.2 8.6 1.5 4 7.0 0.2 2.1 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling HCO3_cotransp PF00955.16 KXX82106.1 - 3.4e-50 171.1 14.4 4.4e-34 118.0 4.0 2.1 2 0 0 2 2 2 2 HCO3- transporter family Presenilin PF01080.12 KXX82106.1 - 0.057 12.2 3.1 0.1 11.3 2.2 1.4 1 0 0 1 1 1 0 Presenilin SET PF00856.23 KXX82107.1 - 1.6e-10 41.5 0.0 7.2e-10 39.4 0.0 2.0 1 1 1 2 2 2 1 SET domain Pyridox_oxidase PF01243.15 KXX82109.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 KXX82110.1 - 2.9e-15 56.6 0.0 3.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX82110.1 - 1.4e-06 28.2 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX82110.1 - 2.1e-05 24.2 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 KR domain BTG PF07742.7 KXX82110.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 BTG family Lipase_GDSL PF00657.17 KXX82111.1 - 1.5e-12 47.9 0.1 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_76 PF03663.9 KXX82113.1 - 7.1e-129 430.3 5.9 8.7e-129 430.0 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 KXX82113.1 - 0.0062 14.8 0.2 0.074 11.3 0.0 2.1 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 KXX82113.1 - 0.045 12.7 2.7 2.6 7.0 0.0 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 KXX82114.1 - 7.4e-62 209.3 0.0 9e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF871 PF05913.6 KXX82114.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Xpo1 PF08389.7 KXX82116.1 - 3.4e-27 95.1 1.1 1.2e-26 93.4 0.1 2.5 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KXX82116.1 - 0.00073 19.4 1.9 0.019 14.8 0.1 3.3 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 KXX82116.1 - 0.013 15.9 6.6 0.57 10.7 0.0 6.0 7 0 0 7 7 7 0 HEAT-like repeat Adaptin_N PF01602.15 KXX82116.1 - 0.075 11.3 0.2 0.95 7.6 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region RabGAP-TBC PF00566.13 KXX82117.1 - 2e-47 161.4 0.1 5.3e-47 160.0 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Leu_zip PF15294.1 KXX82117.1 - 6.3e-05 22.2 8.7 8.1e-05 21.8 3.2 2.4 2 0 0 2 2 2 1 Leucine zipper IncA PF04156.9 KXX82117.1 - 0.0036 16.9 5.3 0.0036 16.9 3.7 3.5 4 0 0 4 4 4 2 IncA protein DUF1664 PF07889.7 KXX82117.1 - 0.28 10.9 9.0 0.11 12.3 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KXX82117.1 - 0.61 7.8 2.6 1.2 6.8 1.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tmemb_cc2 PF10267.4 KXX82117.1 - 5.1 5.5 19.9 0.069 11.7 1.5 2.6 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Prominin PF05478.6 KXX82117.1 - 5.7 4.3 10.5 0.084 10.3 2.1 1.6 2 0 0 2 2 2 0 Prominin AAA_13 PF13166.1 KXX82117.1 - 5.9 5.2 10.2 1.2 7.4 4.3 1.8 2 0 0 2 2 2 0 AAA domain Reticulon PF02453.12 KXX82118.1 - 1.1e-38 132.5 4.6 1.6e-38 131.9 3.2 1.2 1 0 0 1 1 1 1 Reticulon HET PF06985.6 KXX82120.1 - 7.9e-12 45.5 0.0 9.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.12 KXX82121.1 - 2.8e-13 49.7 15.8 2.8e-13 49.7 10.9 1.5 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 KXX82122.1 - 2.3e-33 113.4 0.9 3.9e-33 112.6 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KXX82122.1 - 3.8e-29 100.0 9.9 9.2e-29 98.8 6.9 1.7 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KXX82122.1 - 7.9e-19 67.1 0.7 1.5e-18 66.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RRN7 PF11781.3 KXX82122.1 - 1.5e-06 27.5 3.7 1.5e-06 27.5 2.6 2.3 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 Ubiquitin_2 PF14560.1 KXX82122.1 - 8.9e-05 22.6 0.3 0.00021 21.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KXX82122.1 - 0.0016 18.1 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KXX82122.1 - 0.08 13.1 0.2 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Pex24p PF06398.6 KXX82123.1 - 4.5e-103 344.7 0.0 5.5e-103 344.5 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MIF4G PF02854.14 KXX82125.1 - 1.3e-62 210.9 0.0 1.1e-31 109.9 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KXX82125.1 - 8e-53 178.7 12.4 8e-53 178.7 8.6 2.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Chitin_synth_2 PF03142.10 KXX82126.1 - 5.1e-22 77.9 1.6 5.1e-22 77.9 1.1 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KXX82126.1 - 4.1e-19 69.2 0.0 8.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KXX82126.1 - 3e-18 66.2 7.9 3e-18 66.2 5.5 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KXX82126.1 - 0.015 14.9 0.1 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 MMS1_N PF10433.4 KXX82127.1 - 3.3e-97 325.7 0.0 5.4e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KXX82127.1 - 0.00065 18.8 0.0 0.047 12.7 0.0 2.9 2 1 0 2 2 2 1 CPSF A subunit region RabGAP-TBC PF00566.13 KXX82128.1 - 3.1e-24 85.6 0.0 3.9e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KXX82130.1 - 7.5e-18 63.6 9.5 1.3e-08 34.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PAS_3 PF08447.6 KXX82131.1 - 1.1e-16 60.7 0.0 1.6e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 KXX82131.1 - 6.5e-12 45.7 0.0 1.9e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KXX82131.1 - 7.5e-09 35.3 0.0 0.00032 20.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KXX82131.1 - 2.6e-05 24.2 0.0 0.031 14.2 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KXX82131.1 - 0.00014 21.7 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 KXX82131.1 - 0.013 15.3 0.0 0.96 9.4 0.0 2.7 3 0 0 3 3 3 0 PAS domain Yip1 PF04893.12 KXX82132.1 - 1.5e-12 47.3 15.7 2.4e-12 46.6 10.9 1.5 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KXX82132.1 - 0.0043 16.7 8.7 0.0073 15.9 6.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Na_Ca_ex PF01699.19 KXX82133.1 - 6.6e-22 77.6 18.3 1.1e-15 57.4 2.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DEAD PF00270.24 KXX82134.1 - 1.2e-24 86.7 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 KXX82134.1 - 1.4e-12 48.0 0.3 3.9e-12 46.5 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 KXX82134.1 - 1.5e-08 34.3 0.0 4.9e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Terminase_GpA PF05876.7 KXX82134.1 - 0.13 10.5 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Ran_BP1 PF00638.13 KXX82135.1 - 2.1e-11 43.9 0.2 0.0002 21.4 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain zf-RING_2 PF13639.1 KXX82136.1 - 1.3e-15 56.8 16.9 2.1e-14 53.0 5.5 2.2 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 KXX82136.1 - 8.8e-11 41.3 10.8 3.1e-09 36.3 3.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KXX82136.1 - 1.5e-08 34.4 1.3 1.5e-08 34.4 0.9 2.4 2 0 0 2 2 2 1 zinc-finger zf-rbx1 PF12678.2 KXX82136.1 - 2.8e-08 33.7 7.9 2.6e-07 30.6 2.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KXX82136.1 - 1.5e-06 27.7 16.1 3.7e-05 23.2 5.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX82136.1 - 2.7e-06 27.3 17.0 4.2e-06 26.6 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX82136.1 - 4.4e-05 23.1 4.9 4.4e-05 23.1 3.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KXX82136.1 - 0.0016 18.2 6.3 0.0087 15.8 2.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 KXX82136.1 - 0.0048 16.5 13.0 0.36 10.5 2.5 3.0 2 1 0 3 3 3 2 Prokaryotic RING finger family 1 HypA PF01155.14 KXX82136.1 - 0.0081 15.8 0.3 0.0081 15.8 0.2 1.7 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KXX82136.1 - 0.01 15.6 0.2 0.01 15.6 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-P11 PF03854.9 KXX82136.1 - 0.011 15.1 2.7 0.011 15.1 1.9 1.7 2 0 0 2 2 2 0 P-11 zinc finger zf-ribbon_3 PF13248.1 KXX82136.1 - 0.027 13.6 0.3 0.027 13.6 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Baculo_RING PF05883.6 KXX82136.1 - 0.036 13.8 3.9 0.36 10.6 1.0 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 KXX82136.1 - 0.79 9.4 14.3 1.5 8.5 4.4 2.5 2 0 0 2 2 2 0 PHD-finger zf-FPG_IleRS PF06827.9 KXX82136.1 - 1.1 8.9 4.2 6.1 6.5 0.4 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Prok-RING_4 PF14447.1 KXX82136.1 - 1.3 8.5 11.5 0.058 12.9 2.4 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KXX82136.1 - 2.8 7.5 11.8 1.3 8.7 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KXX82136.1 - 5.1 7.0 13.6 0.49 10.3 0.8 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KXX82136.1 - 6.1 6.8 12.1 7.4 6.6 4.8 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain Fis1_TPR_C PF14853.1 KXX82137.1 - 1.8e-25 88.5 1.1 2.5e-25 88.0 0.8 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KXX82137.1 - 2.2e-16 58.8 0.0 3.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KXX82137.1 - 0.0015 18.2 1.2 0.0035 17.1 0.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX82137.1 - 0.023 15.3 0.1 0.042 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat p450 PF00067.17 KXX82138.1 - 8.7e-52 176.1 0.0 1.3e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4099 PF13351.1 KXX82138.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) Rhodanese PF00581.15 KXX82139.1 - 1.1e-16 61.1 0.0 2.5e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain DUF1565 PF07602.6 KXX82139.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DASH_Ask1 PF08655.5 KXX82140.1 - 3.8e-33 113.1 0.1 6.2e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 TATR PF03430.8 KXX82141.1 - 0.1 11.2 1.5 0.1 11.2 1.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Spc97_Spc98 PF04130.8 KXX82142.1 - 1.2e-68 231.8 0.0 1.8e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 KXX82143.1 - 5.3e-28 96.8 0.0 5.3e-28 96.8 0.0 1.6 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Myc_N PF01056.13 KXX82143.1 - 1.4 8.0 9.6 2.6 7.1 6.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 KXX82143.1 - 7.5 4.3 10.0 10 3.8 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family Vint PF14623.1 KXX82144.1 - 1.4e-39 135.1 0.0 2.3e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KXX82144.1 - 5e-29 100.2 0.0 7.9e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KXX82144.1 - 1.6e-16 60.8 0.0 2.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KXX82144.1 - 3.7e-15 56.0 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KXX82144.1 - 1.1e-11 44.6 0.0 3.5e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1664 PF07889.7 KXX82145.1 - 0.02 14.6 1.9 0.038 13.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF445 PF04286.7 KXX82145.1 - 0.073 12.5 0.8 0.41 10.1 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) TBPIP PF07106.8 KXX82145.1 - 0.074 12.5 2.5 0.14 11.7 1.7 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3571 PF12095.3 KXX82145.1 - 0.16 12.2 0.6 0.56 10.4 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) DUF3584 PF12128.3 KXX82146.1 - 0.00063 17.2 2.5 0.00063 17.2 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Spectrin PF00435.16 KXX82146.1 - 0.094 13.0 2.7 0.35 11.1 0.5 2.8 2 0 0 2 2 2 0 Spectrin repeat ETC_C1_NDUFA5 PF04716.9 KXX82148.1 - 2.1e-22 78.3 2.6 3.1e-22 77.8 0.5 2.2 2 0 0 2 2 2 1 ETC complex I subunit conserved region Mo-co_dimer PF03404.11 KXX82149.1 - 2.8e-56 188.7 0.0 5.2e-56 187.8 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KXX82149.1 - 5.3e-50 169.1 0.0 8.8e-50 168.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KXX82149.1 - 1e-29 102.5 0.0 1.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KXX82149.1 - 1.4e-25 90.0 0.0 2.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KXX82149.1 - 1.4e-23 82.4 0.0 2.5e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KXX82149.1 - 0.00099 19.0 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HSP70 PF00012.15 KXX82150.1 - 6.7e-165 549.4 6.5 2.6e-164 547.4 4.5 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX82150.1 - 2.1e-10 39.7 0.0 1.9e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KXX82150.1 - 0.00015 21.6 0.5 0.22 11.3 0.1 3.6 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 KXX82150.1 - 0.062 13.2 0.1 0.24 11.3 0.1 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal Ala_racemase_C PF00842.16 KXX82150.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Alanine racemase, C-terminal domain V_ATPase_I PF01496.14 KXX82150.1 - 0.99 7.1 9.6 1.4 6.6 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_EFTU PF00009.22 KXX82151.1 - 5.8e-33 113.9 0.0 2.6e-32 111.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KXX82151.1 - 3e-18 65.6 0.0 7.5e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KXX82151.1 - 2.1e-09 37.3 9.8 2.8e-07 30.5 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KXX82151.1 - 1.2e-06 28.4 0.0 5.3e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KXX82151.1 - 0.00036 20.1 0.1 0.0012 18.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KXX82151.1 - 0.00076 19.9 1.1 0.0032 17.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KXX82151.1 - 0.011 15.3 0.4 0.05 13.2 0.3 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 4 FeoB_N PF02421.13 KXX82151.1 - 0.02 14.1 0.0 0.33 10.2 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 KXX82151.1 - 0.051 13.5 0.0 0.051 13.5 0.0 3.6 2 1 0 2 2 2 0 AAA ATPase domain Vps52 PF04129.7 KXX82152.1 - 9e-122 407.1 0.0 1.1e-121 406.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KXX82152.1 - 9.4e-06 24.0 0.6 2.4e-05 22.7 0.4 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 KXX82152.1 - 0.00077 19.4 0.1 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Mer2 Filament PF00038.16 KXX82152.1 - 0.035 13.5 0.1 0.065 12.6 0.1 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF1664 PF07889.7 KXX82152.1 - 0.043 13.6 0.1 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 KXX82152.1 - 0.063 13.1 0.5 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 eIF-5a PF01287.15 KXX82153.1 - 3.9e-27 93.9 1.4 5.5e-27 93.5 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KXX82153.1 - 0.00027 20.5 0.5 0.00054 19.5 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KXX82153.1 - 0.0013 18.5 0.2 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Dynamin_N PF00350.18 KXX82154.1 - 0.0043 16.9 0.1 0.0044 16.8 0.0 1.0 1 0 0 1 1 1 1 Dynamin family Cu-oxidase_3 PF07732.10 KXX82155.1 - 3.8e-28 97.5 0.0 4.4e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KXX82155.1 - 0.00072 19.0 0.3 0.0042 16.6 0.2 1.9 1 1 0 1 1 1 1 Multicopper oxidase DUF3818 PF12825.2 KXX82156.1 - 1.2e-32 112.9 0.0 1.7e-20 73.0 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KXX82156.1 - 4.5e-32 110.5 0.0 9.7e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 PX-associated DUF2317 PF10079.4 KXX82158.1 - 0.32 9.5 7.8 0.54 8.8 5.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF972 PF06156.8 KXX82158.1 - 2 8.8 5.5 0.58 10.5 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Thiolase_N PF00108.18 KXX82159.1 - 8.4e-73 244.5 1.7 1.2e-72 244.1 1.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX82159.1 - 1.8e-40 137.2 1.6 4.9e-40 135.7 1.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Phage_tube PF04985.9 KXX82159.1 - 0.056 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein FII DUF342 PF03961.8 KXX82162.1 - 0.00085 17.8 10.0 0.00085 17.8 6.9 3.7 2 1 2 4 4 4 2 Protein of unknown function (DUF342) Hemagglutinin PF00509.13 KXX82162.1 - 0.02 13.0 2.5 0.048 11.8 1.7 1.5 1 0 0 1 1 1 0 Haemagglutinin GTP1_OBG PF01018.17 KXX82164.1 - 1.4e-38 132.0 2.2 3.6e-28 98.1 2.6 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KXX82164.1 - 2.2e-20 72.7 0.0 3.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KXX82164.1 - 6.4e-06 25.5 0.1 1.7e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 KXX82164.1 - 0.0073 15.1 0.0 0.22 10.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 KXX82164.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 KXX82164.1 - 0.093 11.9 0.0 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Nol1_Nop2_Fmu PF01189.12 KXX82165.1 - 8.2e-32 110.7 0.0 3.2e-19 69.4 0.0 4.8 4 1 0 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KXX82165.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX82165.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase FoP_duplication PF13865.1 KXX82165.1 - 7.4 7.0 8.8 23 5.4 6.1 1.9 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Fungal_trans PF04082.13 KXX82166.1 - 4.3e-24 84.7 0.3 6.5e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TatD_DNase PF01026.16 KXX82167.1 - 3.3e-28 98.5 0.0 4.5e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Spc24 PF08286.6 KXX82169.1 - 7e-40 135.4 0.1 4.3e-38 129.6 0.0 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 KXX82169.1 - 0.0011 18.2 2.1 0.0013 17.9 1.4 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Streptin-Immun PF11083.3 KXX82169.1 - 0.0022 17.9 0.7 0.071 13.1 0.0 2.2 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein DUF1633 PF07794.6 KXX82169.1 - 0.0069 14.4 0.1 0.0092 14.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) DUF4164 PF13747.1 KXX82169.1 - 0.047 13.8 11.9 0.13 12.3 8.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Mu-like_Pro PF10123.4 KXX82169.1 - 0.078 12.4 1.9 0.093 12.1 1.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein APG6 PF04111.7 KXX82169.1 - 0.089 11.8 4.6 0.12 11.4 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MAGSP PF03082.9 KXX82169.1 - 0.094 12.0 0.6 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein V_ATPase_I PF01496.14 KXX82169.1 - 0.11 10.3 0.2 0.11 10.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HOOK PF05622.7 KXX82169.1 - 0.12 10.2 4.3 0.15 9.8 3.0 1.1 1 0 0 1 1 1 0 HOOK protein Nsp1_C PF05064.8 KXX82169.1 - 0.15 11.6 3.5 5.5 6.6 1.2 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Blo-t-5 PF11642.3 KXX82169.1 - 0.17 11.6 2.1 0.29 10.9 1.5 1.4 1 0 0 1 1 1 0 Mite allergen Blo t 5 FUSC PF04632.7 KXX82169.1 - 0.19 10.0 4.6 0.21 9.9 3.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.17 KXX82169.1 - 0.2 11.6 2.6 1.1 9.2 0.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Troponin PF00992.15 KXX82169.1 - 0.28 11.2 3.4 0.41 10.7 2.4 1.2 1 0 0 1 1 1 0 Troponin DUF724 PF05266.9 KXX82169.1 - 0.31 10.6 3.3 0.5 9.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRE1 PF08647.6 KXX82169.1 - 0.32 10.9 5.2 0.54 10.2 2.3 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase XhlA PF10779.4 KXX82169.1 - 0.32 10.9 3.2 0.37 10.7 1.2 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Prefoldin_2 PF01920.15 KXX82169.1 - 0.58 9.9 5.9 0.92 9.2 1.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit HALZ PF02183.13 KXX82169.1 - 0.79 9.4 3.9 0.68 9.7 1.4 1.8 2 0 0 2 2 1 0 Homeobox associated leucine zipper FlxA PF14282.1 KXX82169.1 - 0.83 9.6 7.0 0.42 10.5 2.9 1.8 1 1 1 2 2 2 0 FlxA-like protein GAS PF13851.1 KXX82169.1 - 1.7 7.8 6.3 1.4 8.0 1.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Viral_P18 PF04521.8 KXX82169.1 - 1.8 8.0 8.3 0.83 9.1 0.8 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SlyX PF04102.7 KXX82169.1 - 2 8.8 6.2 3.2 8.2 0.9 2.6 1 1 0 2 2 2 0 SlyX ADIP PF11559.3 KXX82169.1 - 2.2 8.1 11.3 1.3 8.9 4.2 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 KXX82169.1 - 2.6 7.4 7.7 18 4.6 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 KXX82169.1 - 2.9 7.7 8.8 5.2 6.9 2.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding M PF02370.11 KXX82169.1 - 3.5 8.3 6.0 50 4.7 2.1 2.8 2 0 0 2 2 2 0 M protein repeat IncA PF04156.9 KXX82169.1 - 4.2 6.9 14.3 19 4.7 9.9 1.8 1 1 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 KXX82169.1 - 4.6 7.7 6.6 7.7 6.9 0.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Claudin_3 PF06653.6 KXX82170.1 - 0.26 11.0 3.4 2.6 7.7 0.1 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like RNA_pol_Rpb5_C PF01191.14 KXX82171.1 - 1.3e-35 120.8 0.2 2.4e-35 119.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KXX82171.1 - 1.5e-31 108.6 0.0 2.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KXX82171.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease AAA_3 PF07726.6 KXX82171.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GMC_oxred_N PF00732.14 KXX82172.1 - 9.7e-52 175.9 0.3 4.5e-51 173.7 0.2 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX82172.1 - 2.4e-30 105.7 0.0 4.5e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX82172.1 - 3.2e-09 36.1 0.4 4.5e-05 22.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX82172.1 - 4.7e-05 23.3 0.2 0.00015 21.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX82172.1 - 5.6e-05 22.1 0.0 0.0015 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX82172.1 - 0.0062 16.6 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX82172.1 - 0.0076 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KXX82172.1 - 0.053 11.9 0.0 0.42 9.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF3378 PF11858.3 KXX82172.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) NAD_binding_9 PF13454.1 KXX82172.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX82172.1 - 0.58 10.0 4.7 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KXX82173.1 - 5e-13 49.3 0.1 1.2e-12 48.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82173.1 - 2e-07 30.8 0.1 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KXX82173.1 - 0.00012 22.1 0.1 0.00048 20.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KXX82173.1 - 0.0039 16.1 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.1 KXX82173.1 - 0.005 16.6 0.1 0.008 15.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX82173.1 - 0.0075 15.7 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX82173.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KXX82173.1 - 0.031 14.3 0.1 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KXX82173.1 - 0.067 12.1 0.1 0.09 11.7 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 KXX82173.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family FAD_binding_4 PF01565.18 KXX82174.1 - 2.1e-16 59.6 2.3 3.7e-16 58.8 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX82174.1 - 3.4e-11 42.8 0.7 7.2e-11 41.8 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX82174.1 - 0.14 11.2 0.3 0.23 10.5 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ketoacyl-synt PF00109.21 KXX82176.1 - 5.7e-76 255.3 0.0 1.4e-75 254.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX82176.1 - 2.3e-54 183.8 1.7 2.2e-53 180.6 0.0 3.1 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KXX82176.1 - 2.9e-47 160.6 0.3 2.1e-45 154.6 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KXX82176.1 - 3.9e-45 154.5 0.7 7.1e-45 153.7 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KXX82176.1 - 4.1e-38 131.2 0.8 8e-38 130.2 0.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KXX82176.1 - 4.4e-29 100.7 0.0 3.7e-27 94.5 0.0 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KXX82176.1 - 2.1e-28 98.9 0.0 3.7e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KXX82176.1 - 8.2e-18 64.7 0.0 2.3e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX82176.1 - 3.3e-12 46.4 0.0 1e-11 44.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82176.1 - 3.3e-10 40.3 0.0 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82176.1 - 6.4e-10 38.8 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KXX82176.1 - 1e-09 38.1 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 KXX82176.1 - 7.4e-08 32.9 0.0 5.4e-07 30.1 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82176.1 - 3.5e-07 29.5 0.0 6.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KXX82176.1 - 5.6e-05 22.2 0.0 0.00017 20.6 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 KXX82176.1 - 0.00015 21.9 0.1 0.00042 20.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KXX82176.1 - 0.0029 16.3 0.0 2 7.0 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 KXX82176.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase ACP_syn_III PF08545.5 KXX82176.1 - 0.025 14.2 0.8 0.12 12.0 0.4 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HTH_38 PF13936.1 KXX82176.1 - 0.043 13.3 0.1 15 5.1 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain NodS PF05401.6 KXX82176.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) adh_short_C2 PF13561.1 KXX82176.1 - 0.069 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase POLO_box PF00659.13 KXX82176.1 - 0.77 9.7 0.0 1.7 8.6 0.0 1.5 1 0 0 1 1 1 0 POLO box duplicated region RrnaAD PF00398.15 KXX82176.1 - 1.1 8.2 0.0 2.1 7.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ADH_N PF08240.7 KXX82178.1 - 0.00012 21.8 0.0 0.0015 18.2 0.0 2.6 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX82178.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3636 PF12331.3 KXX82179.1 - 2.9e-43 146.9 0.0 6.1e-43 145.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) HTH_IclR PF09339.5 KXX82179.1 - 0.11 12.0 3.3 0.29 10.7 2.3 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF287 PF03384.9 KXX82179.1 - 4.8 7.4 7.3 0.74 10.0 0.0 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Histone_HNS PF00816.16 KXX82179.1 - 5.3 7.6 9.2 66 4.1 0.0 2.6 2 0 0 2 2 2 0 H-NS histone family CTP_transf_1 PF01148.15 KXX82180.1 - 4.3e-78 262.5 28.5 5.3e-78 262.2 19.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 KXX82181.1 - 1.4e-69 233.9 0.1 2.9e-69 233.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX82181.1 - 2.8e-40 136.5 0.2 6e-40 135.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain EF-hand_10 PF14788.1 KXX82181.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 EF hand Glyco_hydro_cc PF11790.3 KXX82182.1 - 2.8e-68 229.9 0.1 3.2e-68 229.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 KXX82182.1 - 0.0055 16.3 0.2 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain adh_short PF00106.20 KXX82183.1 - 1.1e-20 74.1 0.3 1.7e-20 73.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82183.1 - 1.1e-11 44.7 0.3 1.5e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX82183.1 - 3.6e-07 30.2 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX82183.1 - 3.8e-05 23.2 0.0 5.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX82183.1 - 0.0038 17.2 0.1 0.0067 16.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX82183.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dynamin_N PF00350.18 KXX82184.1 - 2e-28 99.3 0.0 4.8e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX82184.1 - 2.1e-09 36.6 0.0 4.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KXX82184.1 - 3.4e-05 23.7 0.0 0.00011 22.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX82184.1 - 0.0043 17.5 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Phe_tRNA-synt_N PF02912.13 KXX82184.1 - 0.0078 15.9 0.0 0.029 14.0 0.0 2.0 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain ABC_tran PF00005.22 KXX82184.1 - 0.0089 16.3 0.0 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter DUF3141 PF11339.3 KXX82184.1 - 0.073 11.4 0.6 0.11 10.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) GED PF02212.13 KXX82184.1 - 0.16 11.9 1.7 0.46 10.4 1.2 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain MFS_1 PF07690.11 KXX82185.1 - 1.1e-23 83.5 36.6 4e-23 81.6 23.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF221 PF02714.10 KXX82187.1 - 5.5e-94 314.6 19.3 1.1e-93 313.6 13.4 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KXX82187.1 - 2.2e-43 147.5 0.6 2.2e-43 147.5 0.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KXX82187.1 - 4.1e-17 62.4 0.1 7.5e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Imm3 PF14425.1 KXX82187.1 - 0.098 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 Trehalose_PPase PF02358.11 KXX82188.1 - 1.2e-45 155.3 0.0 1.7e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Aminotran_4 PF01063.14 KXX82188.1 - 2.7e-21 76.1 0.0 4.1e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Hydrolase_3 PF08282.7 KXX82188.1 - 0.021 14.4 0.0 0.18 11.3 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 KXX82190.1 - 2.1e-85 277.8 21.2 3.5e-16 58.3 0.5 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KXX82190.1 - 2e-07 30.9 0.4 0.0013 18.4 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KXX82190.1 - 0.00019 19.7 2.3 0.76 7.8 0.0 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 KXX82190.1 - 0.025 14.5 0.1 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain FAD_binding_9 PF08021.6 KXX82190.1 - 0.047 13.6 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain DUF1707 PF08044.6 KXX82190.1 - 0.081 12.6 0.2 0.081 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Baculo_helicase PF04735.7 KXX82190.1 - 0.42 7.9 0.0 0.58 7.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase Glyco_transf_20 PF00982.16 KXX82191.1 - 6.6e-157 522.7 0.0 8.2e-157 522.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KXX82191.1 - 0.0069 15.8 0.3 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain LAP2alpha PF11560.3 KXX82191.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha TPR_2 PF07719.12 KXX82192.1 - 2.6e-11 42.5 13.9 8.1e-05 22.2 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX82192.1 - 3.1e-11 42.7 12.7 5.1e-10 38.8 1.4 5.1 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.1 KXX82192.1 - 1e-09 38.8 3.5 1e-09 38.8 2.4 3.9 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX82192.1 - 1.9e-09 36.7 7.8 0.0028 17.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX82192.1 - 1.1e-08 34.8 7.5 0.0087 15.9 0.1 4.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX82192.1 - 2.5e-08 33.1 2.0 0.012 15.3 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX82192.1 - 4.8e-05 23.6 4.6 0.0024 18.3 0.2 6.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KXX82192.1 - 0.00013 22.2 3.3 0.021 15.1 1.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX82192.1 - 0.00043 20.2 1.5 0.049 13.8 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX82192.1 - 0.0018 17.8 3.0 0.05 13.4 0.0 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX82192.1 - 0.016 15.6 5.6 19 5.9 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 KXX82192.1 - 0.16 11.3 2.6 3.9 6.8 0.2 3.6 4 1 1 5 5 5 0 26S proteasome subunit RPN7 MARVEL PF01284.18 KXX82194.1 - 6.1e-09 35.8 9.7 8.4e-09 35.3 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4583 PF15190.1 KXX82194.1 - 8.9 5.9 7.7 3.5 7.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4583) Glyco_hydro_43 PF04616.9 KXX82195.1 - 3.1e-106 354.6 1.1 5.3e-106 353.8 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Methyltransf_31 PF13847.1 KXX82196.1 - 1.5e-27 96.0 0.0 2e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82196.1 - 3.7e-26 91.4 0.0 6.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82196.1 - 2e-16 60.5 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82196.1 - 2.3e-16 60.0 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82196.1 - 9.7e-16 57.5 0.0 2.1e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KXX82196.1 - 7.2e-15 55.0 0.1 1.6e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82196.1 - 8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX82196.1 - 4.2e-13 49.3 0.0 5.2e-13 49.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX82196.1 - 4.4e-09 35.9 0.0 6.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KXX82196.1 - 2.6e-07 30.4 0.0 3.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KXX82196.1 - 8.5e-06 24.9 0.0 2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 KXX82196.1 - 5.1e-05 22.7 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 KXX82196.1 - 5.3e-05 22.5 0.1 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 KXX82196.1 - 6.5e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KXX82196.1 - 0.00029 19.9 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 KXX82196.1 - 0.00054 19.5 0.0 0.00076 19.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.12 KXX82196.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 KXX82196.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 KXX82196.1 - 0.002 18.9 0.0 0.0044 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KXX82196.1 - 0.0026 16.4 0.0 0.0034 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DUF938 PF06080.7 KXX82196.1 - 0.0031 17.0 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 KXX82196.1 - 0.0035 16.5 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 KXX82196.1 - 0.0036 15.6 0.0 0.0058 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.13 KXX82196.1 - 0.0084 15.4 0.0 2.4 7.3 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain p450 PF00067.17 KXX82197.1 - 1.1e-33 116.4 0.0 4e-30 104.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PDCD2_C PF04194.8 KXX82197.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain adh_short PF00106.20 KXX82198.1 - 1.9e-28 99.5 4.0 2.7e-28 98.9 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX82198.1 - 5.7e-23 81.9 0.5 7e-23 81.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX82198.1 - 2.8e-13 49.9 0.7 1e-12 48.0 0.2 1.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KXX82198.1 - 0.0023 17.4 0.2 0.0034 16.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KXX82198.1 - 0.016 15.3 0.0 0.41 10.8 0.0 2.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain Cutinase PF01083.17 KXX82200.1 - 6.1e-53 179.1 6.1 7e-53 178.9 4.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KXX82200.1 - 8e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KXX82200.1 - 0.00028 20.5 0.1 0.00064 19.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX82200.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82200.1 - 0.052 13.3 0.5 0.12 12.1 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 KXX82200.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) p450 PF00067.17 KXX82201.1 - 3.8e-60 203.7 0.0 5.3e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADP_ribosyl_GH PF03747.9 KXX82202.1 - 3.7e-64 217.2 6.6 4.3e-64 217.0 4.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sulfate_transp PF00916.15 KXX82204.1 - 9.3e-54 182.3 1.9 1.8e-53 181.3 1.3 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX82204.1 - 3.7e-27 93.7 3.3 1.4e-26 91.9 2.3 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KXX82204.1 - 7.9e-17 60.7 0.0 1.9e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 KXX82204.1 - 0.0016 18.3 0.0 0.0045 16.9 0.0 1.9 1 1 0 1 1 1 1 STAS domain PepSY_TM_3 PF13706.1 KXX82204.1 - 4 6.9 12.0 7.6 6.0 1.4 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix Fungal_trans_2 PF11951.3 KXX82205.1 - 1.6e-29 102.6 0.0 2.2e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82205.1 - 3.9e-05 23.4 9.1 7.2e-05 22.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 KXX82206.1 - 1e-29 103.6 0.0 3.1e-29 102.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase zf-RING_2 PF13639.1 KXX82206.1 - 3.4e-05 23.5 5.5 9.7e-05 22.1 3.2 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KXX82206.1 - 0.00049 19.7 0.1 0.0012 18.4 0.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX82206.1 - 0.0013 18.7 3.4 0.0028 17.7 2.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KXX82206.1 - 0.0064 16.1 1.3 0.02 14.5 0.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX82206.1 - 0.01 15.8 0.6 0.01 15.8 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S11 PF00768.15 KXX82206.1 - 0.067 12.4 0.0 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase zf-RING_5 PF14634.1 KXX82206.1 - 0.098 12.4 0.9 0.24 11.1 0.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PAD PF03068.10 KXX82207.1 - 1.7e-43 148.5 0.0 1.3e-42 145.6 0.0 2.2 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) DUF4360 PF14273.1 KXX82208.1 - 1.4e-54 184.5 0.5 1.6e-54 184.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) GYF PF02213.11 KXX82209.1 - 9.7e-19 66.7 0.1 2e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain SnoaL PF07366.7 KXX82210.1 - 0.0021 17.6 0.0 0.005 16.4 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 KXX82210.1 - 0.02 14.1 0.1 0.054 12.7 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.19 KXX82211.1 - 1.3e-13 50.7 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KXX82211.1 - 1.1e-08 34.6 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KXX82211.1 - 4.3e-05 23.6 0.0 6.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX82211.1 - 0.00098 19.2 0.0 0.0025 17.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KXX82211.1 - 0.0019 18.3 0.3 0.012 15.7 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX82211.1 - 0.074 12.9 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KXX82211.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 KXX82212.1 - 2.1e-09 37.0 1.3 5.3e-09 35.7 0.9 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KXX82212.1 - 2e-07 31.1 0.9 4.3e-07 30.0 0.6 1.6 1 0 0 1 1 1 1 Complex1_LYR-like 5_nucleotid_C PF02872.13 KXX82214.1 - 6.5e-38 130.1 0.0 1.9e-37 128.6 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KXX82214.1 - 7.7e-07 28.7 0.1 1.2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FYVE PF01363.16 KXX82215.1 - 7.9e-22 76.9 24.4 8.2e-17 60.8 4.2 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 KXX82215.1 - 7.8e-06 25.3 0.5 2.8e-05 23.5 0.4 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 KXX82215.1 - 0.00086 19.1 3.2 0.00086 19.1 2.2 3.3 3 0 0 3 3 3 2 AN1-like Zinc finger zf-Di19 PF05605.7 KXX82215.1 - 0.094 12.8 12.3 0.11 12.6 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CK_II_beta PF01214.13 KXX82215.1 - 0.15 11.5 0.9 0.53 9.7 0.6 1.9 1 0 0 1 1 1 0 Casein kinase II regulatory subunit zf-C2H2_2 PF12756.2 KXX82215.1 - 0.62 10.1 0.0 0.62 10.1 0.0 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HC5 PF06221.8 KXX82215.1 - 2.9 7.7 20.9 0.44 10.3 0.2 4.5 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type CENP-L PF13092.1 KXX82216.1 - 3.8e-49 166.5 0.0 5.6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ank_4 PF13637.1 KXX82217.1 - 1e-16 60.9 2.6 5.6e-09 36.2 0.1 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX82217.1 - 5.5e-15 55.4 0.0 9.1e-06 25.9 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82217.1 - 2.7e-13 49.0 1.1 9.6e-06 25.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KXX82217.1 - 4.4e-13 49.0 0.2 0.0001 22.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82217.1 - 3.8e-12 45.1 0.3 0.00035 20.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KXX82217.1 - 1.8e-05 24.3 0.0 0.00011 21.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain FliJ PF02050.11 KXX82217.1 - 0.028 14.4 8.9 0.098 12.7 6.2 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein Laminin_II PF06009.7 KXX82217.1 - 0.03 14.0 2.8 0.06 13.0 2.0 1.4 1 0 0 1 1 1 0 Laminin Domain II NAD_binding_7 PF13241.1 KXX82218.1 - 1.4e-34 118.4 0.0 1.9e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KXX82218.1 - 9.7e-27 92.0 0.0 1.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KXX82218.1 - 6.6e-16 56.9 0.2 1.1e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 KXX82218.1 - 0.0033 17.2 1.0 0.0065 16.2 0.0 1.8 1 1 1 2 2 2 1 ThiF family Shikimate_DH PF01488.15 KXX82218.1 - 0.0065 16.5 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Peptidase_S8 PF00082.17 KXX82219.1 - 6.9e-08 31.9 0.3 0.0024 17.0 0.0 2.5 2 1 0 2 2 2 2 Subtilase family HET PF06985.6 KXX82220.1 - 1.4e-20 73.8 0.1 3.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.17 KXX82221.1 - 3e-168 559.9 0.1 3.5e-168 559.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RhodobacterPufX PF11511.3 KXX82222.1 - 0.057 12.8 0.1 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF4337 PF14235.1 KXX82222.1 - 0.95 9.2 3.3 1.6 8.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec3_C PF09763.4 KXX82224.1 - 0.5 8.4 1.2 0.7 7.9 0.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 tRNA-synt_2 PF00152.15 KXX82225.1 - 3.1e-71 239.8 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KXX82225.1 - 7.4e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KXX82225.1 - 1.7e-06 27.4 0.1 0.0012 18.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.10 KXX82226.1 - 2.3e-19 68.4 2.5 2.6e-19 68.2 1.7 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KXX82226.1 - 0.0011 18.4 2.2 0.0016 17.8 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) HATPase_c PF02518.21 KXX82227.1 - 1.6e-22 79.3 0.0 3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KXX82227.1 - 3.1e-17 62.5 0.3 2.7e-13 49.9 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain PAS_9 PF13426.1 KXX82227.1 - 4.1e-11 43.1 0.0 2.9e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KXX82227.1 - 1.3e-08 34.8 0.0 0.00014 21.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KXX82227.1 - 6.9e-07 29.1 1.9 1.2e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KXX82227.1 - 5.1e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 KXX82227.1 - 0.0036 17.8 0.0 0.94 9.9 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 KXX82227.1 - 0.0057 16.4 0.0 0.026 14.4 0.0 2.2 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.1 KXX82227.1 - 0.012 15.6 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 GAF domain PH_6 PF15406.1 KXX82228.1 - 1.4e-47 160.4 4.5 1.4e-47 160.4 3.1 4.4 4 1 2 6 6 6 1 Pleckstrin homology domain PH PF00169.24 KXX82228.1 - 0.0043 17.2 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KXX82228.1 - 0.14 11.7 0.0 0.14 11.7 0.0 3.9 4 0 0 4 4 4 0 Pleckstrin homology domain PBP1_TM PF14812.1 KXX82228.1 - 0.23 11.8 8.8 4.3 7.7 1.2 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4598 PF15370.1 KXX82228.1 - 7.7 6.8 15.1 4.3 7.6 3.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) UPF0197 PF05251.7 KXX82229.1 - 0.0023 18.2 6.9 0.011 16.0 4.8 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) Rad1 PF02144.11 KXX82230.1 - 7.1e-88 293.9 0.0 8.1e-88 293.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Mago-bind PF09282.5 KXX82231.1 - 3e-15 55.4 3.4 6.2e-15 54.4 2.4 1.6 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.7 KXX82231.1 - 0.15 11.9 16.2 0.19 11.6 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4612 PF15389.1 KXX82231.1 - 0.3 11.6 8.9 0.55 10.8 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) DUF2201_N PF13203.1 KXX82231.1 - 0.8 8.8 10.5 1.1 8.3 7.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Borrelia_P83 PF05262.6 KXX82231.1 - 1.8 6.7 13.6 1.8 6.7 9.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Vfa1 PF08432.5 KXX82231.1 - 2.6 8.0 15.6 4 7.4 10.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 KXX82231.1 - 3.5 7.3 5.9 4.1 7.1 4.1 1.3 1 0 0 1 1 1 0 DDHD domain MRL1 PF13003.2 KXX82231.1 - 4 7.2 7.8 2.5 7.8 3.8 1.8 1 1 1 2 2 2 0 Ribosomal protein L1 Spore_coat_CotO PF14153.1 KXX82231.1 - 4 6.8 14.5 5.7 6.3 10.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Presenilin PF01080.12 KXX82231.1 - 4.3 6.0 4.5 4.5 5.9 3.1 1.1 1 0 0 1 1 1 0 Presenilin RNase_H2-Ydr279 PF09468.5 KXX82231.1 - 6.6 5.8 10.8 8.8 5.4 7.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ycf1 PF05758.7 KXX82231.1 - 8.7 3.9 9.0 10 3.7 6.2 1.0 1 0 0 1 1 1 0 Ycf1 Tom37_C PF11801.3 KXX82231.1 - 9 6.1 7.3 14 5.4 5.1 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1510 PF07423.6 KXX82231.1 - 9.1 5.5 15.7 14 4.9 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) UCR_UQCRX_QCR9 PF05365.7 KXX82232.1 - 4.1e-26 90.3 1.7 4.9e-26 90.1 1.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like WavE PF07507.6 KXX82232.1 - 0.097 11.5 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis IQ PF00612.22 KXX82233.1 - 3.1e-06 26.3 1.2 1e-05 24.7 0.8 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.4 KXX82233.1 - 0.00011 21.8 6.5 0.00011 21.8 4.5 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein ABC_tran PF00005.22 KXX82234.1 - 2e-31 109.1 0.0 3.9e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KXX82234.1 - 2.7e-08 33.5 9.0 2.7e-08 33.5 6.2 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 KXX82234.1 - 8.7e-08 31.6 0.0 1.3e-06 27.8 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KXX82234.1 - 1e-05 25.6 0.0 0.0096 15.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX82234.1 - 0.0024 17.0 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KXX82234.1 - 0.0031 18.3 0.0 0.0072 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KXX82234.1 - 0.01 14.9 0.3 0.022 13.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KXX82234.1 - 0.015 15.6 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX82234.1 - 0.019 14.5 0.1 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 KXX82234.1 - 0.052 13.4 0.1 0.25 11.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KXX82234.1 - 0.059 13.3 0.3 0.46 10.4 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KXX82234.1 - 0.086 12.9 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KXX82234.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KXX82234.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PX PF00787.19 KXX82235.1 - 6.7e-21 74.2 0.0 1.1e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 PX domain adh_short PF00106.20 KXX82236.1 - 4.3e-22 78.7 6.8 7.5e-22 78.0 4.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82236.1 - 5e-13 49.1 1.8 8.1e-13 48.4 1.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX82236.1 - 6.7e-11 42.4 0.1 9.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX82236.1 - 8.6e-09 35.6 0.7 5.8e-08 32.9 0.5 2.2 2 1 1 3 3 3 1 NADH(P)-binding Epimerase PF01370.16 KXX82236.1 - 1.1e-08 34.7 0.2 1.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KXX82236.1 - 0.00021 20.2 1.2 0.00037 19.4 0.8 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KXX82236.1 - 0.00022 20.5 0.4 0.00039 19.7 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KXX82236.1 - 0.0048 16.8 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KXX82236.1 - 0.0054 15.7 0.2 0.0079 15.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 KXX82236.1 - 0.0075 15.4 0.0 0.0095 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 KXX82236.1 - 0.034 13.6 0.5 0.068 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ribosomal_S11 PF00411.14 KXX82237.1 - 3e-11 43.4 0.2 5.1e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4160 PF13711.1 KXX82237.1 - 0.28 11.0 1.9 0.81 9.5 1.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4160) BCS1_N PF08740.6 KXX82238.1 - 3.1e-44 150.8 0.0 4.5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KXX82238.1 - 1.1e-20 74.1 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX82238.1 - 1.7e-05 23.9 0.0 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KXX82238.1 - 2.2e-05 24.5 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX82238.1 - 4.7e-05 24.2 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX82238.1 - 9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KXX82238.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KXX82238.1 - 0.00045 19.6 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KXX82238.1 - 0.0022 17.8 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KXX82238.1 - 0.0022 17.7 0.2 0.018 14.7 0.1 2.6 1 1 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KXX82238.1 - 0.0033 16.3 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX82238.1 - 0.011 15.2 0.4 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KXX82238.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KXX82238.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KXX82238.1 - 0.032 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KXX82238.1 - 0.034 14.4 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KXX82238.1 - 0.047 12.7 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KXX82238.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 1 0 ABC transporter AAA_21 PF13304.1 KXX82238.1 - 0.049 13.5 0.1 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KXX82238.1 - 0.049 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 KXX82238.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 KXX82238.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KXX82238.1 - 0.09 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KXX82238.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 KXX82238.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KXX82238.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KXX82238.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TIP49 PF06068.8 KXX82238.1 - 0.21 10.2 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF1768 PF08719.6 KXX82239.1 - 2.3e-42 144.4 0.0 2.7e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.10 KXX82240.1 - 8e-33 113.4 0.0 8e-33 113.4 0.0 2.3 2 0 0 2 2 2 1 Tim44-like domain CDC45 PF02724.9 KXX82240.1 - 0.16 9.9 13.8 0.21 9.5 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Sec62 PF03839.11 KXX82240.1 - 0.71 9.2 20.3 0.67 9.3 9.7 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 DUF913 PF06025.7 KXX82240.1 - 8.8 4.9 6.6 17 3.9 4.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CLTH PF10607.4 KXX82241.1 - 5.5e-29 100.7 0.0 1.2e-28 99.6 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KXX82241.1 - 1.7e-15 56.4 2.7 3.2e-15 55.5 1.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KXX82241.1 - 0.00022 20.9 1.9 0.00036 20.2 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 KXX82241.1 - 0.0014 17.8 0.1 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 KXX82241.1 - 0.0022 17.9 2.5 0.0037 17.2 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX82241.1 - 0.0024 17.4 1.2 0.0037 16.8 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Flagellin_C PF00700.16 KXX82241.1 - 0.024 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region zf-RING_5 PF14634.1 KXX82241.1 - 0.034 13.8 1.6 0.055 13.2 1.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX82241.1 - 0.06 13.2 3.0 0.11 12.3 2.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_16 PF13432.1 KXX82241.1 - 0.19 12.4 5.6 3.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KXX82241.1 - 0.35 10.5 2.9 0.63 9.7 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HlyIII PF03006.15 KXX82242.1 - 7.1e-59 198.8 19.7 8.8e-59 198.5 13.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related Tex_N PF09371.5 KXX82242.1 - 0.12 11.6 0.5 0.24 10.7 0.3 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain An_peroxidase PF03098.10 KXX82242.1 - 0.18 10.1 0.1 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase PG_binding_1 PF01471.13 KXX82243.1 - 7.9e-05 22.5 0.0 0.081 12.9 0.0 3.5 3 0 0 3 3 3 2 Putative peptidoglycan binding domain Ank PF00023.25 KXX82245.1 - 1.7e-98 317.9 10.0 3.9e-09 35.8 0.0 13.9 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.2 KXX82245.1 - 1.4e-87 288.0 7.6 2.9e-18 65.9 0.0 7.7 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX82245.1 - 4.8e-70 224.4 6.2 1.4e-05 24.8 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KXX82245.1 - 1.5e-68 226.0 7.4 1.3e-09 38.2 0.1 8.7 5 3 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX82245.1 - 3.9e-65 214.3 19.0 8.4e-09 35.3 0.0 12.1 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Peptidase_S8 PF00082.17 KXX82245.1 - 1.3e-16 60.5 0.1 2.7e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family HET PF06985.6 KXX82246.1 - 1.5e-28 99.6 0.0 3.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KXX82247.1 - 2.3e-69 233.4 0.0 4e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82247.1 - 5.2e-50 169.9 0.0 8.7e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KXX82247.1 - 2e-28 98.4 0.1 5.1e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KXX82247.1 - 4.6e-18 64.8 0.4 2.7e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KXX82247.1 - 4.8e-16 58.6 0.1 9e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KXX82247.1 - 4.1e-13 49.6 0.1 8.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KXX82247.1 - 4.7e-08 32.3 0.0 3.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 KXX82247.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain LRR_4 PF12799.2 KXX82248.1 - 0.00073 19.1 7.1 6.8 6.4 0.3 6.6 3 2 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KXX82248.1 - 0.00082 19.2 7.1 13 6.2 0.0 7.3 9 0 0 9 9 9 1 Leucine Rich repeat PPP4R2 PF09184.6 KXX82250.1 - 1.3e-08 34.7 0.0 1.3e-08 34.7 0.0 2.7 2 1 1 3 3 3 1 PPP4R2 Spt20 PF12090.3 KXX82250.1 - 0.0015 17.9 0.9 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 Spt20 family Suf PF05843.9 KXX82250.1 - 0.12 12.1 16.3 0.3 10.7 1.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CDK2AP PF09806.4 KXX82250.1 - 0.62 10.2 22.2 0.86 9.8 4.8 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Pup PF05639.6 KXX82250.1 - 0.99 9.9 0.0 0.99 9.9 0.0 3.0 3 0 0 3 3 3 0 Pup-like protein FimP PF09766.4 KXX82250.1 - 5.5 5.9 14.9 0.39 9.7 6.0 1.9 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 KXX82250.1 - 8 6.2 28.5 7.3 6.3 10.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CRPA PF05745.6 KXX82251.1 - 0.091 12.5 6.1 0.54 10.0 0.1 3.2 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4064 PF13273.1 KXX82251.1 - 0.41 10.7 16.2 1.2 9.2 4.2 4.0 2 2 0 3 3 3 0 Protein of unknown function (DUF4064) PsbI PF02532.9 KXX82251.1 - 8.4 6.1 8.4 0.51 10.0 0.3 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribophorin_II PF05817.9 KXX82252.1 - 4e-24 84.8 2.1 2.2e-23 82.3 1.4 1.8 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4622 PF15415.1 KXX82252.1 - 0.14 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) LMBR1 PF04791.11 KXX82252.1 - 0.18 10.3 2.3 0.25 9.9 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cep57_MT_bd PF06657.8 KXX82255.1 - 4.1e-25 87.5 0.9 4.1e-25 87.5 0.6 7.6 7 1 2 9 9 9 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KXX82255.1 - 4.6e-13 48.9 8.8 4.6e-13 48.9 6.1 8.7 5 2 3 8 8 8 3 Centrosome localisation domain of PPC89 ADIP PF11559.3 KXX82255.1 - 0.0019 18.1 9.0 0.0019 18.1 6.2 7.6 6 1 2 8 8 8 2 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KXX82255.1 - 0.026 14.8 80.0 0.11 12.7 2.2 9.1 6 2 3 9 9 9 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 KXX82255.1 - 0.53 9.4 8.8 1.7 7.7 0.7 4.1 2 1 1 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 KXX82255.1 - 1.5 8.3 80.4 0.054 13.0 0.2 7.0 4 1 2 6 6 6 0 IncA protein Beta_elim_lyase PF01212.16 KXX82256.1 - 1.1e-69 234.7 0.0 1.4e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KXX82256.1 - 4.3e-05 22.6 0.0 0.00044 19.3 0.0 1.9 1 1 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KXX82256.1 - 0.0015 16.9 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 KXX82257.1 - 1.5e-16 60.0 0.2 2.6e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82257.1 - 8.9e-06 25.5 11.0 8.9e-06 25.5 7.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fis1_TPR_N PF14852.1 KXX82257.1 - 0.032 13.5 0.0 0.074 12.3 0.0 1.7 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Bromodomain PF00439.20 KXX82258.1 - 1e-25 89.4 0.5 2e-25 88.5 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KXX82258.1 - 1.2e-09 38.1 0.1 2.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX82258.1 - 3.4e-09 36.6 0.0 6.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Trehalase PF01204.13 KXX82259.1 - 3.4e-118 395.5 0.8 2.6e-117 392.5 0.5 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 KXX82259.1 - 0.00081 18.2 0.1 0.0015 17.2 0.1 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase CDP-OH_P_transf PF01066.16 KXX82260.1 - 3.4e-18 65.8 3.0 3.4e-18 65.8 2.1 3.1 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M28 PF04389.12 KXX82261.1 - 2.5e-37 128.3 0.0 3.3e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 KXX82261.1 - 0.02 14.7 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Sulfate_transp PF00916.15 KXX82262.1 - 1.1e-71 241.0 10.1 2e-71 240.2 7.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KXX82262.1 - 3.9e-29 100.1 3.9 3.9e-29 100.1 2.7 3.3 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KXX82262.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-UBR PF02207.15 KXX82263.1 - 1.7e-18 66.1 15.9 3.8e-18 64.9 11.0 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KXX82263.1 - 0.00019 21.0 0.0 0.0006 19.4 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.14 KXX82263.1 - 1.2 8.3 3.5 2.2 7.5 2.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RabGAP-TBC PF00566.13 KXX82264.1 - 5.2e-33 114.3 0.0 4.5e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Methyltransf_18 PF12847.2 KXX82265.1 - 3.2e-12 46.9 0.1 5.5e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82265.1 - 2e-09 37.7 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82265.1 - 1.2e-07 31.9 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX82265.1 - 1.3e-07 31.6 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82265.1 - 1.9e-07 30.7 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82265.1 - 5.1e-07 30.0 0.1 4.1e-06 27.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82265.1 - 5.1e-06 25.7 0.0 1.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KXX82265.1 - 9.5e-06 25.4 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KXX82265.1 - 0.025 13.2 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.9 KXX82265.1 - 0.052 12.9 0.0 0.39 10.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain FimP PF09766.4 KXX82266.1 - 5e-30 104.7 11.9 6.4e-30 104.4 8.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein TSC22 PF01166.13 KXX82266.1 - 0.0084 16.0 4.8 0.5 10.3 0.0 2.6 2 0 0 2 2 2 2 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 KXX82266.1 - 0.027 14.3 9.6 0.37 10.6 2.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KXX82266.1 - 0.25 10.8 8.6 0.89 9.0 2.9 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 KXX82266.1 - 0.41 10.6 15.8 0.74 9.7 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 KXX82266.1 - 0.59 10.5 9.0 4.8 7.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 KXX82266.1 - 0.63 10.1 13.8 0.27 11.2 3.3 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1640 PF07798.6 KXX82266.1 - 1.1 9.2 12.6 28 4.6 8.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Pinin_SDK_memA PF04696.8 KXX82266.1 - 1.4 8.5 10.9 0.24 10.9 3.6 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region PP28 PF10252.4 KXX82266.1 - 1.5 8.9 11.1 0.36 10.8 3.4 2.3 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 K-box PF01486.12 KXX82266.1 - 6.6 6.5 13.1 0.36 10.6 0.3 2.9 2 2 0 2 2 2 0 K-box region Lactonase PF10282.4 KXX82267.1 - 8.6e-05 21.7 0.0 0.0035 16.4 0.0 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller zf-H2C2_2 PF13465.1 KXX82268.1 - 5.4e-19 67.4 8.7 2.9e-07 30.4 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KXX82268.1 - 9.2e-14 50.8 11.3 1.8e-06 27.9 0.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX82268.1 - 5.8e-09 35.6 9.8 6.7e-05 22.9 0.4 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX82268.1 - 1.1e-05 25.3 3.1 0.15 12.2 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX82268.1 - 2.3e-05 24.4 2.0 0.016 15.4 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KXX82268.1 - 0.00085 19.6 5.2 0.031 14.6 0.6 2.1 1 1 1 2 2 2 2 TRAF-type zinc finger CHORD PF04968.7 KXX82268.1 - 0.036 14.2 7.6 2.5 8.3 0.1 3.1 1 1 2 3 3 3 0 CHORD zf-H2C2_5 PF13909.1 KXX82268.1 - 0.079 13.2 4.1 1.7 9.0 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RPAP2_Rtr1 PF04181.8 KXX82268.1 - 0.15 12.1 2.9 2.8 8.0 0.3 2.6 1 1 1 2 2 2 0 Rtr1/RPAP2 family Prefoldin_2 PF01920.15 KXX82269.1 - 1.4e-24 85.8 3.1 2e-24 85.4 2.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Seryl_tRNA_N PF02403.17 KXX82269.1 - 0.21 11.6 8.1 3.8 7.5 2.8 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 KXX82269.1 - 0.28 11.5 3.0 7.8 6.9 0.8 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AAA_23 PF13476.1 KXX82269.1 - 0.74 10.1 5.8 0.95 9.7 4.0 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KXX82269.1 - 3 7.3 6.4 12 5.4 0.0 2.0 2 0 0 2 2 2 0 IncA protein DUF2951 PF11166.3 KXX82269.1 - 4 7.3 8.1 13 5.7 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4200 PF13863.1 KXX82269.1 - 4.6 7.1 12.1 0.63 9.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Band_7 PF01145.20 KXX82270.1 - 2.3e-26 92.7 2.4 3.8e-26 92.0 1.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DEAD PF00270.24 KXX82271.1 - 3e-34 117.9 0.0 8e-34 116.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KXX82271.1 - 1.2e-20 72.7 0.0 2.2e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KXX82271.1 - 8.2e-19 67.2 0.0 2.5e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX82271.1 - 0.0024 17.7 0.0 0.013 15.3 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Abhydrolase_6 PF12697.2 KXX82272.1 - 2.1e-22 80.1 1.8 3e-22 79.6 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82272.1 - 7.3e-16 58.2 0.3 9.3e-16 57.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX82272.1 - 5.1e-06 26.2 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KXX82272.1 - 7.9e-06 25.5 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KXX82272.1 - 0.00029 21.1 0.2 0.00041 20.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 KXX82272.1 - 0.00086 18.5 0.1 0.0012 18.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KXX82272.1 - 0.0039 16.8 0.2 0.0075 15.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KXX82272.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KXX82272.1 - 0.011 15.3 0.1 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.3 KXX82272.1 - 0.029 13.5 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Pro_CA PF00484.14 KXX82272.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Carbonic anhydrase AXE1 PF05448.7 KXX82272.1 - 0.16 10.3 1.7 0.68 8.3 0.2 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Skp1_POZ PF03931.10 KXX82274.1 - 7.1e-15 54.8 0.0 9.4e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 KXX82275.1 - 3.1e-50 169.8 0.0 4.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KXX82275.1 - 2.3e-07 30.4 0.7 3.7e-07 29.7 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DASH_Dad1 PF08649.5 KXX82276.1 - 2.6e-24 84.6 1.1 3.4e-24 84.3 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PilJ PF13675.1 KXX82276.1 - 0.039 14.2 0.5 0.042 14.1 0.3 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term WVELL PF14043.1 KXX82276.1 - 0.063 12.8 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 WVELL protein Ras PF00071.17 KXX82277.1 - 1.3e-47 161.1 0.0 1.7e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX82277.1 - 6.8e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX82277.1 - 2.1e-05 23.8 0.0 4.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Ima1_N PF09779.4 KXX82278.1 - 1.9e-40 138.4 1.4 2.9e-40 137.7 1.0 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 KXX82278.1 - 1 9.0 5.2 0.63 9.7 0.6 2.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 KXX82278.1 - 1.3 8.8 7.8 0.097 12.5 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon RNHCP PF12647.2 KXX82278.1 - 2.3 8.0 5.9 0.45 10.3 0.2 2.4 3 0 0 3 3 3 0 RNHCP domain Sec6 PF06046.8 KXX82279.1 - 1.2e-157 525.3 11.5 1.7e-157 524.9 8.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KXX82279.1 - 0.00029 19.7 1.0 0.00029 19.7 0.7 2.0 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 KXX82279.1 - 0.017 14.0 1.7 0.036 12.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF2173 PF09941.4 KXX82279.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) COX7C PF02935.11 KXX82281.1 - 1.2e-13 50.5 0.5 1.4e-13 50.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Tcf25 PF04910.9 KXX82282.1 - 1.8e-73 247.5 2.1 2.7e-73 246.9 1.5 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 ATC_hydrolase PF14196.1 KXX82282.1 - 0.016 15.6 0.4 0.22 11.9 0.1 2.5 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Vpu PF00558.14 KXX82282.1 - 0.78 9.3 6.7 4.2 6.9 0.8 2.7 2 0 0 2 2 2 0 Vpu protein MRP-S25 PF13741.1 KXX82283.1 - 2.5e-25 89.3 0.6 2.9e-25 89.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 DUF507 PF04368.8 KXX82283.1 - 0.0091 15.6 0.1 0.011 15.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF507) P22_Cro PF14549.1 KXX82283.1 - 0.075 12.7 0.4 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro Mor PF08765.6 KXX82283.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.3 1 1 0 1 1 1 0 Mor transcription activator family DUF2934 PF11154.3 KXX82283.1 - 0.27 10.6 0.1 0.27 10.6 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2934) Alg14 PF08660.6 KXX82284.1 - 6.2e-46 156.4 0.0 8.5e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Steroid_dh PF02544.11 KXX82285.1 - 9.5e-22 77.3 0.1 9.5e-22 77.3 0.1 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KXX82285.1 - 7.9e-05 22.7 0.4 0.00032 20.7 0.3 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 KXX82285.1 - 0.0023 17.2 0.1 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GCN5L1 PF06320.8 KXX82286.1 - 5.6e-07 29.4 0.3 9.5e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF4106 PF13388.1 KXX82286.1 - 0.028 13.3 3.2 0.041 12.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) IncA PF04156.9 KXX82286.1 - 0.1 12.1 0.6 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 KXX82286.1 - 0.14 12.3 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PAT1 PF09770.4 KXX82286.1 - 0.68 8.1 10.3 0.86 7.7 7.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med13_N PF11597.3 KXX82286.1 - 0.73 8.4 9.0 0.56 8.8 4.8 1.7 1 1 1 2 2 2 0 Mediator complex subunit 13 N-terminal SOG2 PF10428.4 KXX82287.1 - 1.9e-108 363.0 0.1 1.9e-108 363.0 0.1 2.6 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 KXX82287.1 - 2.1e-16 59.0 7.4 5e-08 32.3 0.9 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX82287.1 - 2.9e-15 55.7 3.7 1.2e-08 34.6 0.8 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KXX82287.1 - 4e-09 35.2 5.0 0.071 13.1 0.1 6.0 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KXX82287.1 - 3.6e-05 23.2 1.7 9.8 6.8 0.0 5.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KXX82287.1 - 1.2 9.3 5.2 25 5.3 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Helicase_C PF00271.26 KXX82288.1 - 1.3e-18 66.6 0.0 5.1e-16 58.3 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KXX82288.1 - 1e-15 57.6 0.0 3.6e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2407_C PF13373.1 KXX82289.1 - 4e-31 107.8 0.0 6.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KXX82289.1 - 5.8e-27 93.7 0.0 8.9e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TrbC PF04956.8 KXX82289.1 - 0.0081 16.1 1.7 0.014 15.4 1.2 1.4 1 0 0 1 1 1 1 TrbC/VIRB2 family rRNA_proc-arch PF13234.1 KXX82290.1 - 3.1e-94 315.0 0.0 1e-93 313.3 0.0 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KXX82290.1 - 3.5e-55 186.0 2.8 7e-55 185.0 1.9 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KXX82290.1 - 8.2e-21 74.2 0.0 3.1e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX82290.1 - 3e-08 33.4 0.0 6.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX82290.1 - 0.0024 17.7 0.1 0.037 13.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Prp19 PF08606.6 KXX82290.1 - 0.0027 17.4 0.8 0.47 10.2 0.1 2.7 2 0 0 2 2 2 1 Prp19/Pso4-like T2SE PF00437.15 KXX82290.1 - 0.0052 15.7 0.0 0.091 11.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DDE_1 PF03184.14 KXX82291.1 - 1.8e-42 144.9 0.0 2.6e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 KXX82291.1 - 1.9e-11 43.3 0.0 6e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KXX82291.1 - 2.9e-08 33.3 0.0 7.7e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 KXX82291.1 - 0.0043 16.8 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 KXX82291.1 - 0.018 15.0 0.0 0.84 9.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 KXX82291.1 - 0.12 12.0 0.2 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain HET PF06985.6 KXX82292.1 - 3.7e-33 114.6 0.1 5.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ydc2-catalyt PF09159.5 KXX82293.1 - 4.8e-58 196.8 0.0 5.7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 KXX82293.1 - 2.6e-05 23.5 0.3 6.8e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 KXX82293.1 - 0.069 13.0 0.0 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A22 protein Pyr_redox_2 PF07992.9 KXX82294.1 - 4.2e-41 141.0 0.0 8.1e-41 140.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KXX82294.1 - 1.4e-32 111.9 0.2 4.3e-32 110.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KXX82294.1 - 1.2e-18 67.2 4.3 5.3e-17 61.9 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX82294.1 - 1.3e-10 41.7 0.1 1e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KXX82294.1 - 7.5e-05 21.7 0.1 0.0038 16.2 0.0 2.5 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KXX82294.1 - 0.00024 20.2 0.3 0.00042 19.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KXX82294.1 - 0.00035 19.1 4.6 0.49 8.7 1.2 3.1 2 1 1 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.16 KXX82294.1 - 0.00098 18.7 0.4 0.71 9.4 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KXX82294.1 - 0.0017 17.3 0.6 0.0073 15.2 0.2 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 KXX82294.1 - 0.026 13.6 0.7 0.056 12.5 0.5 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KXX82294.1 - 0.035 12.9 6.1 1.1 8.0 2.0 2.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 KXX82294.1 - 0.044 12.6 4.4 0.11 11.3 1.7 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX82294.1 - 0.13 12.3 2.4 0.4 10.7 1.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KXX82294.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.2 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RasGEF PF00617.14 KXX82295.1 - 2.1e-50 171.0 0.0 4e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KXX82295.1 - 1.6e-14 53.8 0.3 3.4e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif CTP_transf_1 PF01148.15 KXX82296.1 - 1.1e-16 61.2 7.8 6e-14 52.3 2.2 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF2244 PF10003.4 KXX82296.1 - 0.43 9.9 3.0 0.52 9.6 1.0 2.0 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) DUF3984 PF13136.1 KXX82296.1 - 0.59 9.2 6.1 1.1 8.3 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) zf-HIT PF04438.11 KXX82297.1 - 2.9e-09 36.4 7.8 5.3e-09 35.5 5.4 1.5 1 0 0 1 1 1 1 HIT zinc finger MspA PF09203.6 KXX82297.1 - 0.04 13.3 0.6 0.067 12.6 0.4 1.3 1 0 0 1 1 1 0 MspA DENN PF02141.16 KXX82298.1 - 4.9e-40 137.2 0.0 8.7e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KXX82298.1 - 1.5e-05 24.8 0.9 4.7e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 uDENN domain Elongin_A PF06881.6 KXX82298.1 - 0.0041 17.4 3.1 0.0041 17.4 2.2 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Dfp1_Him1_M PF08630.5 KXX82298.1 - 0.056 13.2 1.7 0.56 9.9 1.1 2.3 2 0 0 2 2 2 0 Dfp1/Him1, central region DUF3135 PF11333.3 KXX82298.1 - 0.24 11.5 4.3 0.63 10.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Met_10 PF02475.11 KXX82299.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KXX82299.1 - 0.012 15.6 1.2 0.026 14.5 0.8 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF2470 PF10615.4 KXX82300.1 - 8e-16 58.0 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) EF-hand_7 PF13499.1 KXX82302.1 - 2.8e-09 36.9 0.8 2.8e-09 36.9 0.5 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KXX82302.1 - 2.6e-08 33.0 0.5 0.00081 19.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KXX82302.1 - 2.2e-07 29.6 1.0 2.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KXX82302.1 - 1.1e-06 27.6 0.7 9.8e-06 24.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KXX82302.1 - 0.00045 19.7 1.9 0.00084 18.8 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair Pirin PF02678.11 KXX82303.1 - 7.8e-32 109.3 0.0 3e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KXX82303.1 - 1.4e-26 92.5 0.0 1.3e-25 89.4 0.1 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KXX82303.1 - 4.1e-10 39.0 2.2 8e-06 25.2 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KXX82303.1 - 0.00012 21.3 0.7 0.21 11.0 0.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF861) Perilipin PF03036.11 KXX82304.1 - 0.00014 20.8 0.2 0.00035 19.5 0.1 1.6 1 1 0 1 1 1 1 Perilipin family Histidinol_dh PF00815.15 KXX82304.1 - 0.064 11.8 0.0 0.083 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Fungal_trans PF04082.13 KXX82305.1 - 7.8e-14 51.1 0.3 1.5e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82305.1 - 9.6e-08 31.8 7.4 1.9e-07 30.8 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 KXX82306.1 - 2.6e-24 86.1 0.6 6.6e-24 84.7 0.4 1.6 1 1 0 1 1 1 1 Phosphoesterase family Ras PF00071.17 KXX82307.1 - 3.6e-16 58.9 0.0 8.9e-16 57.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KXX82307.1 - 6.6e-09 36.2 0.0 1.8e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KXX82307.1 - 5.6e-05 22.4 0.0 0.00017 20.8 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KXX82307.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KXX82307.1 - 0.0021 18.1 0.1 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.13 KXX82307.1 - 0.0055 15.7 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Septin IIGP PF05049.8 KXX82307.1 - 0.0063 15.3 0.3 0.027 13.2 0.2 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KXX82307.1 - 0.0064 16.3 0.0 0.97 9.2 0.1 2.3 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 KXX82307.1 - 0.0064 15.6 0.0 0.0064 15.6 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KXX82307.1 - 0.0071 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 KXX82307.1 - 0.014 15.0 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KXX82307.1 - 0.016 14.6 0.9 0.025 14.0 0.1 1.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KXX82307.1 - 0.038 13.7 0.0 0.088 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KXX82307.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 KXX82307.1 - 0.047 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 KXX82307.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.7 KXX82307.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AIG1 PF04548.11 KXX82307.1 - 0.084 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 KXX82307.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KXX82307.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KXX82307.1 - 0.097 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Arf PF00025.16 KXX82307.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 KXX82307.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KXX82307.1 - 0.13 11.8 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KXX82308.1 - 1.6e-54 183.6 0.0 1.2e-38 132.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX82308.1 - 5.8e-12 45.8 0.2 0.00044 20.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KXX82308.1 - 1.9e-10 40.2 0.2 4.3e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 KXX82308.1 - 1.4e-09 37.5 0.3 0.0007 19.2 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain AAA_16 PF13191.1 KXX82308.1 - 1.7e-09 37.9 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KXX82308.1 - 2.5e-09 36.9 0.1 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KXX82308.1 - 4.3e-09 36.3 0.0 0.0004 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KXX82308.1 - 1.1e-08 34.2 0.0 0.00097 17.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 KXX82308.1 - 1.2e-08 35.8 0.0 0.0065 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KXX82308.1 - 1.6e-08 34.9 0.0 0.0043 17.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.7 KXX82308.1 - 4.5e-08 32.4 0.1 0.0023 17.0 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus CDC48_N PF02359.13 KXX82308.1 - 4.8e-08 32.8 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.16 KXX82308.1 - 2.4e-07 30.1 0.2 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KXX82308.1 - 2.8e-07 30.5 0.0 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KXX82308.1 - 4.8e-07 29.8 0.0 0.00015 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KXX82308.1 - 2.7e-06 26.9 0.9 0.12 11.7 0.0 3.5 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 KXX82308.1 - 4.4e-06 26.8 0.0 0.089 12.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KXX82308.1 - 4.5e-06 26.1 0.1 0.14 11.5 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein ABC_tran PF00005.22 KXX82308.1 - 6.5e-06 26.4 0.0 0.037 14.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 KXX82308.1 - 1.4e-05 24.7 0.2 0.065 12.8 0.2 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KXX82308.1 - 1.8e-05 23.9 0.0 0.024 13.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 KXX82308.1 - 2.1e-05 24.2 1.4 0.02 14.5 0.0 3.3 4 0 0 4 4 3 1 NACHT domain KaiC PF06745.8 KXX82308.1 - 4.7e-05 22.6 0.1 0.023 13.8 0.1 2.5 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 KXX82308.1 - 8.2e-05 22.1 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KXX82308.1 - 9.1e-05 21.7 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 KXX82308.1 - 0.00011 21.1 0.1 0.19 10.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.1 KXX82308.1 - 0.00012 22.1 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KXX82308.1 - 0.00017 21.2 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KXX82308.1 - 0.00046 19.9 0.1 9.4 5.8 0.0 3.8 2 2 1 4 4 4 0 Archaeal ATPase AAA_3 PF07726.6 KXX82308.1 - 0.0008 19.0 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KXX82308.1 - 0.00091 19.0 0.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KXX82308.1 - 0.0016 17.5 0.0 0.6 9.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 KXX82308.1 - 0.0026 16.6 0.0 0.95 8.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KXX82308.1 - 0.0033 17.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KXX82308.1 - 0.0037 16.5 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 KXX82308.1 - 0.0048 16.5 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 KXX82308.1 - 0.0056 16.1 0.1 3.5 7.0 0.0 3.8 2 2 1 4 4 4 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 KXX82308.1 - 0.01 15.8 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KXX82308.1 - 0.015 14.8 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.17 KXX82308.1 - 0.026 14.3 0.1 9.3 6.0 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase cobW PF02492.14 KXX82308.1 - 0.028 13.8 0.1 0.93 8.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KXX82308.1 - 0.036 12.9 0.0 4.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KXX82308.1 - 0.038 13.4 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain CPT PF07931.7 KXX82308.1 - 0.041 13.4 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein HATPase_c PF02518.21 KXX82308.1 - 0.054 13.2 0.1 12 5.7 0.1 2.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TrwB_AAD_bind PF10412.4 KXX82308.1 - 0.1 11.2 0.1 7 5.1 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DAP3 PF10236.4 KXX82308.1 - 0.14 11.1 0.1 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.13 KXX82308.1 - 0.21 11.0 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cir_N PF10197.4 KXX82309.1 - 0.0018 18.2 0.3 0.0018 18.2 0.2 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Mito_fiss_reg PF05308.6 KXX82311.1 - 0.89 8.8 14.0 0.24 10.7 7.5 1.6 1 1 1 2 2 2 0 Mitochondrial fission regulator PAT1 PF09770.4 KXX82311.1 - 6.4 4.8 10.5 7.8 4.5 7.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 KxDL PF10241.4 KXX82312.1 - 3e-33 113.5 2.3 4e-33 113.1 1.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Syntaxin PF00804.20 KXX82312.1 - 0.063 13.4 2.5 0.1 12.8 0.2 2.0 1 1 1 2 2 2 0 Syntaxin Mating_C PF12737.2 KXX82312.1 - 0.16 10.8 9.0 0.53 9.1 1.0 2.3 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 DUF883 PF05957.8 KXX82312.1 - 1.8 9.0 7.4 7.6 7.0 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Aminotran_1_2 PF00155.16 KXX82313.1 - 3.6e-63 213.7 0.0 4.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KXX82313.1 - 3.2e-05 23.1 0.0 5.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KXX82313.1 - 8e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KXX82313.1 - 0.00031 19.1 0.0 0.00048 18.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KXX82313.1 - 0.0078 14.9 0.0 0.018 13.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V CcmH PF03918.9 KXX82314.1 - 0.089 11.7 0.7 0.43 9.5 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein LSM14 PF12701.2 KXX82315.1 - 4e-36 122.7 0.0 4.4e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 KXX82315.1 - 3e-06 27.0 0.0 3.7e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.5 KXX82316.1 - 9.9e-21 74.2 1.7 9.9e-21 74.2 1.1 2.6 3 0 0 3 3 3 1 FDF domain Fungal_trans PF04082.13 KXX82318.1 - 2.1e-11 43.2 0.3 4.3e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Choline_kinase PF01633.15 KXX82319.1 - 5e-06 26.2 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KXX82319.1 - 0.0029 17.3 1.5 0.0091 15.7 0.2 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family HMA PF00403.21 KXX82320.1 - 3.5e-15 55.8 0.3 5.1e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Clr5 PF14420.1 KXX82321.1 - 2.8e-18 65.5 0.9 6.7e-18 64.3 0.6 1.7 1 0 0 1 1 1 1 Clr5 domain Rogdi_lz PF10259.4 KXX82322.1 - 2.1e-70 236.9 0.0 4.9e-46 157.0 0.0 2.0 1 1 1 2 2 2 2 Rogdi leucine zipper containing protein NIPSNAP PF07978.8 KXX82323.1 - 2e-38 130.4 0.5 3.5e-28 97.5 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.4 KXX82323.1 - 0.047 13.1 5.4 0.074 12.5 3.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_tran PF00005.22 KXX82324.1 - 3.6e-50 169.8 0.0 2.2e-27 96.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KXX82324.1 - 1.1e-15 58.3 2.8 1.1e-05 25.5 0.1 3.8 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KXX82324.1 - 2e-12 46.7 0.1 0.0023 17.1 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KXX82324.1 - 5.9e-08 33.2 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KXX82324.1 - 1.3e-07 31.0 0.4 0.0066 15.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KXX82324.1 - 1.2e-06 28.4 0.0 0.0072 16.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KXX82324.1 - 2.9e-06 28.1 0.0 0.011 16.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KXX82324.1 - 3e-06 26.5 0.0 0.0096 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 KXX82324.1 - 3.1e-06 26.7 0.1 6.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 KXX82324.1 - 3.7e-06 26.7 0.0 0.078 12.8 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KXX82324.1 - 3.3e-05 24.3 0.0 0.097 13.1 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 KXX82324.1 - 6.1e-05 22.2 0.0 1.3 7.9 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KXX82324.1 - 7.9e-05 22.8 0.6 0.86 9.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KXX82324.1 - 0.00018 21.0 2.6 0.31 10.4 0.1 3.5 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 KXX82324.1 - 0.00061 19.6 0.0 0.8 9.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KXX82324.1 - 0.0011 18.9 0.0 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX82324.1 - 0.0012 18.2 0.0 2.1 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KXX82324.1 - 0.0013 18.4 0.8 0.36 10.5 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KXX82324.1 - 0.0017 18.0 0.2 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 KXX82324.1 - 0.0019 18.0 0.0 0.61 9.8 0.0 3.2 2 1 1 3 3 3 1 Dynamin family ArgK PF03308.11 KXX82324.1 - 0.0025 16.6 0.4 0.38 9.4 0.0 2.4 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 KXX82324.1 - 0.0027 17.8 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KXX82324.1 - 0.0073 16.6 0.1 0.34 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KXX82324.1 - 0.0087 14.5 0.0 3 6.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KXX82324.1 - 0.012 15.4 3.2 0.35 10.6 0.0 3.3 4 0 0 4 4 2 0 Domain of unknown function DUF87 AAA PF00004.24 KXX82324.1 - 0.014 15.6 0.0 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KXX82324.1 - 0.016 14.7 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KXX82324.1 - 0.016 14.6 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3584 PF12128.3 KXX82324.1 - 0.024 11.9 0.8 2.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_14 PF13173.1 KXX82324.1 - 0.057 13.3 0.0 4.1 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 KXX82324.1 - 0.069 12.5 0.1 6 6.1 0.0 2.5 2 0 0 2 2 2 0 MutS domain V DUF815 PF05673.8 KXX82324.1 - 0.1 11.5 0.1 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KXX82324.1 - 0.12 11.4 1.6 6.3 5.8 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin HEAT PF02985.17 KXX82324.1 - 0.15 12.1 1.1 48 4.4 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat AAA_16 PF13191.1 KXX82324.1 - 0.24 11.3 4.9 1.9 8.4 0.1 3.9 3 1 0 3 3 3 0 AAA ATPase domain HEAT_2 PF13646.1 KXX82324.1 - 0.27 11.5 8.2 1.6 9.0 0.0 4.0 2 2 0 3 3 3 0 HEAT repeats RRM_1 PF00076.17 KXX82325.1 - 6.8e-15 54.4 0.0 1.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX82325.1 - 1.5e-12 47.2 0.0 1.5e-12 47.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX82325.1 - 2.2e-07 30.6 0.6 5.6e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3233 PF11557.3 KXX82325.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) Glyco_hydro_16 PF00722.16 KXX82326.1 - 3e-19 69.0 0.1 1.6e-17 63.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 KXX82326.1 - 0.019 13.1 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Glyco_trans_2_3 PF13632.1 KXX82327.1 - 1.5e-45 155.2 9.1 1.5e-45 155.2 6.3 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KXX82327.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KXX82327.1 - 3.1e-05 23.7 0.0 7.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KXX82327.1 - 0.038 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Rpp20 PF12328.3 KXX82329.1 - 2.7e-27 95.2 0.9 3.4e-27 94.8 0.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KXX82329.1 - 3.9e-17 61.6 0.1 7.2e-17 60.7 0.1 1.5 1 1 0 1 1 1 1 Alba Pkinase PF00069.20 KXX82331.1 - 4.6e-25 88.2 0.0 1.3e-24 86.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82331.1 - 1.1e-11 44.3 0.0 0.00015 20.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KXX82331.1 - 0.0027 17.4 0.2 0.0075 16.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX82331.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kri1_C PF12936.2 KXX82331.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 KRI1-like family C-terminal Kinase-like PF14531.1 KXX82331.1 - 0.039 12.9 0.0 6.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Abhydrolase_6 PF12697.2 KXX82332.1 - 6.8e-09 35.9 0.6 1.3e-08 34.9 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arginase PF00491.16 KXX82333.1 - 6.7e-79 265.0 0.2 8.9e-79 264.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KXX82333.1 - 0.14 12.3 0.2 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain APH PF01636.18 KXX82334.1 - 5.1e-20 72.2 0.1 5.1e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 KXX82335.1 - 1.6e-16 60.8 7.1 2.1e-16 60.5 4.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82335.1 - 3.6e-11 43.0 1.1 5.6e-11 42.3 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82335.1 - 3.1e-05 23.6 1.4 5.1e-05 22.9 0.7 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KXX82335.1 - 0.0096 15.7 0.1 0.53 10.1 0.0 2.7 2 0 0 2 2 2 1 Putative lysophospholipase DUF4215 PF13948.1 KXX82336.1 - 1.5e-35 121.1 246.9 0.001 19.2 1.2 20.1 9 6 12 21 21 21 19 Domain of unknown function (DUF4215) WD40 PF00400.27 KXX82337.1 - 1.2e-31 107.3 0.6 2.5e-05 23.9 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KXX82337.1 - 1.2e-05 24.7 0.0 0.032 13.7 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 KXX82337.1 - 0.025 13.6 0.3 3.5 6.6 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 KXX82337.1 - 0.1 10.8 0.0 1.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) GDC-P PF02347.11 KXX82338.1 - 5.8e-175 582.0 0.0 7.9e-159 528.9 0.0 2.8 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KXX82338.1 - 1.6e-06 27.4 0.1 3.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KXX82338.1 - 0.1 11.5 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Nup54 PF13874.1 KXX82339.1 - 1.2e-44 151.3 0.1 1.2e-44 151.3 0.1 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 V-SNARE_C PF12352.3 KXX82339.1 - 0.0075 16.3 1.5 0.69 10.0 0.0 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus HOOK PF05622.7 KXX82339.1 - 0.056 11.2 6.3 0.3 8.8 3.8 1.9 1 1 1 2 2 2 0 HOOK protein DUF1423 PF07227.6 KXX82339.1 - 0.069 11.7 1.0 0.099 11.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) FlaC_arch PF05377.6 KXX82339.1 - 0.53 10.2 4.7 2.7 7.9 0.5 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KXX82339.1 - 5.2 6.6 17.1 8.6 5.9 0.3 3.3 3 1 0 3 3 3 0 IncA protein HCMV_UL139 PF12507.3 KXX82339.1 - 7.3 6.7 7.7 38 4.4 0.1 3.1 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein CHCH PF06747.8 KXX82340.1 - 1.6e-08 34.2 15.6 2.2e-07 30.6 3.8 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KXX82340.1 - 1.4e-06 27.9 6.0 0.011 15.4 0.1 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 KXX82340.1 - 0.87 9.7 4.1 0.45 10.6 0.7 2.0 2 0 0 2 2 2 0 GCK domain CAP PF00188.21 KXX82341.1 - 6.7e-21 75.0 3.1 9.3e-21 74.5 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fungal_trans PF04082.13 KXX82342.1 - 3.6e-09 35.8 0.1 2.9e-08 32.8 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.15 KXX82343.1 - 6.1e-166 552.2 0.0 8.1e-166 551.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KXX82343.1 - 6e-10 39.0 0.2 1.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KXX82343.1 - 2.9e-07 30.4 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain DUF1691 PF07950.6 KXX82344.1 - 9.8e-41 138.1 5.2 3.4e-26 91.3 1.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Paramyxo_PCT PF14320.1 KXX82344.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered Herpes_US9 PF06072.6 KXX82344.1 - 0.042 13.6 0.8 0.12 12.2 0.5 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 zf-C2H2_jaz PF12171.3 KXX82345.1 - 9.3e-07 28.8 4.4 1.9e-06 27.8 3.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX82345.1 - 0.0001 22.3 0.8 0.0002 21.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KXX82345.1 - 0.0049 17.1 0.2 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KXX82345.1 - 0.014 15.4 0.2 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KXX82345.1 - 0.029 14.7 1.0 0.058 13.7 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF965 PF06135.7 KXX82345.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) p450 PF00067.17 KXX82346.1 - 7.3e-48 163.2 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 KXX82347.1 - 2.1e-19 69.9 0.0 2.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KXX82347.1 - 7.4e-08 31.4 0.0 1.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KXX82347.1 - 3.3e-05 22.9 0.0 0.00014 20.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KXX82347.1 - 0.00016 21.7 0.6 0.00075 19.5 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX82347.1 - 0.02 14.7 6.2 0.047 13.6 2.8 2.3 1 1 1 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.11 KXX82348.1 - 7.6e-33 113.6 26.2 7.6e-33 113.6 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KXX82348.1 - 1.1 9.2 4.9 0.48 10.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Lipase_GDSL_2 PF13472.1 KXX82349.1 - 2e-12 47.6 0.1 3.1e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX82349.1 - 1.1e-10 41.7 0.1 8.2e-10 38.8 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ATP-grasp_4 PF13535.1 KXX82350.1 - 0.0029 17.3 0.0 0.11 12.2 0.0 2.4 2 1 0 2 2 2 2 ATP-grasp domain Hrs_helical PF12210.3 KXX82353.1 - 0.12 12.6 1.0 0.57 10.4 0.1 2.4 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate AMP-binding PF00501.23 KXX82354.1 - 6e-66 222.5 0.0 2.9e-65 220.3 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX82354.1 - 1.1e-10 42.2 0.0 3.3e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KXX82355.1 - 7.4e-29 100.8 1.6 1.1e-28 100.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX82355.1 - 4.4e-18 65.9 0.0 5.3e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX82355.1 - 6.6e-11 42.2 1.3 1e-10 41.5 0.9 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KXX82355.1 - 2.3e-05 24.1 0.2 3.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KXX82355.1 - 0.00051 19.5 0.1 0.00079 18.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 KXX82355.1 - 0.0035 17.7 0.0 0.0075 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82355.1 - 0.01 16.3 0.0 0.05 14.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KXX82355.1 - 0.011 15.4 2.3 0.23 11.2 0.3 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KXX82355.1 - 0.019 13.8 0.1 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KXX82355.1 - 0.033 13.1 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_31 PF13847.1 KXX82355.1 - 0.041 13.4 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 KXX82355.1 - 0.067 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_11 PF08241.7 KXX82355.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82355.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KXX82355.1 - 0.097 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gln-synt_C PF00120.19 KXX82356.1 - 1.2e-61 208.1 0.0 1.5e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Citrate_synt PF00285.16 KXX82357.1 - 3e-102 341.9 0.0 3.5e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Meth_synt_1 PF08267.7 KXX82357.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain ICL PF00463.16 KXX82358.1 - 4.1e-195 648.9 0.2 4.7e-195 648.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KXX82358.1 - 3.5e-11 42.7 0.0 1.2e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase IBR PF01485.16 KXX82359.1 - 3.7 7.4 7.9 5.5 6.9 5.5 1.3 1 0 0 1 1 1 0 IBR domain DUF4360 PF14273.1 KXX82360.1 - 4.1e-73 244.9 4.7 4.8e-73 244.7 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) EHN PF06441.7 KXX82361.1 - 8.1e-31 106.2 0.1 1.5e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KXX82361.1 - 1.5e-08 34.7 1.0 2.9e-08 33.8 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82361.1 - 0.0015 18.0 2.5 0.0022 17.5 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 KXX82362.1 - 3.9e-76 256.4 21.2 4.7e-76 256.1 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX82362.1 - 1.6e-17 63.2 22.4 1.6e-17 63.2 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.8 KXX82364.1 - 8.4e-57 192.0 0.0 1.1e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KXX82364.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82364.1 - 4.5e-06 26.6 0.1 0.0029 17.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX82364.1 - 0.00021 20.7 0.0 0.15 11.4 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 KXX82364.1 - 0.11 11.7 0.0 9.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DLIC PF05783.6 KXX82365.1 - 3.5e-36 124.8 0.0 6.8e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.10 KXX82366.1 - 3.5e-57 192.6 0.0 5.7e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Sigma70_r4 PF04545.11 KXX82366.1 - 0.012 14.8 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Thioredoxin_7 PF13899.1 KXX82366.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like TRAM_LAG1_CLN8 PF03798.11 KXX82367.1 - 2.2e-38 131.8 16.1 3.5e-38 131.1 11.2 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KXX82367.1 - 5.7e-19 67.3 0.1 1.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.17 KXX82369.1 - 4e-16 58.3 0.1 3.7e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX82369.1 - 2e-09 37.2 0.0 3.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX82369.1 - 9.9e-06 25.3 0.0 2.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KXX82370.1 - 9.9e-11 41.0 1.8 0.00044 20.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KXX82370.1 - 0.055 12.9 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain BBE PF08031.7 KXX82370.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Nbas_N PF15492.1 KXX82370.1 - 0.13 11.3 0.0 1.5 7.8 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KXX82371.1 - 4.8e-107 357.1 0.1 1e-106 356.1 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KXX82371.1 - 6.1e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX82371.1 - 0.0014 18.4 4.6 0.46 10.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KXX82371.1 - 0.0028 16.8 0.2 0.0064 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 KXX82371.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 KXX82371.1 - 0.024 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX82371.1 - 0.035 13.9 0.7 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KXX82371.1 - 0.04 13.3 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KXX82371.1 - 0.041 14.0 0.1 0.15 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 KXX82371.1 - 0.049 14.1 0.3 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 KXX82371.1 - 0.064 12.3 0.2 0.16 11.0 0.1 1.7 1 1 0 1 1 1 0 AIG1 family AAA_17 PF13207.1 KXX82371.1 - 0.085 13.6 4.1 0.21 12.4 0.1 2.8 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KXX82371.1 - 0.28 10.6 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family V_ATPase_I PF01496.14 KXX82371.1 - 1 7.1 2.5 1.6 6.4 1.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3653 PF12375.3 KXX82371.1 - 3.2 8.0 7.9 1.7e+02 2.5 0.0 3.1 2 1 0 2 2 2 0 Phage protein Bax1-I PF01027.15 KXX82372.1 - 7.6e-49 166.1 26.5 8.8e-49 165.8 18.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Herpes_UL43 PF05072.8 KXX82372.1 - 0.037 12.7 8.6 0.012 14.3 3.9 1.6 1 1 0 1 1 1 0 Herpesvirus UL43 protein DUF754 PF05449.6 KXX82372.1 - 0.062 13.3 5.8 0.15 12.0 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF754) DUF368 PF04018.8 KXX82372.1 - 0.093 11.8 16.6 0.038 13.1 5.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Spore_YhaL PF14147.1 KXX82372.1 - 0.13 11.7 0.1 0.49 9.8 0.1 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL Orbi_NS3 PF01616.11 KXX82372.1 - 0.36 9.7 3.5 1.1 8.1 0.2 2.3 2 0 0 2 2 2 0 Orbivirus NS3 DUF4407 PF14362.1 KXX82372.1 - 5 5.9 13.4 4.5 6.1 4.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) MFS_1 PF07690.11 KXX82375.1 - 1.4e-15 56.9 31.1 1.4e-15 56.9 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 KXX82377.1 - 8.7e-27 92.9 16.2 8.7e-27 92.9 11.2 3.3 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 GTP_EFTU PF00009.22 KXX82379.1 - 8e-41 139.5 3.4 6e-40 136.6 2.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KXX82379.1 - 4e-25 87.8 0.2 1.1e-24 86.4 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KXX82379.1 - 9.6e-14 51.2 8.6 4.7e-09 36.2 0.1 3.5 4 0 0 4 4 4 2 Elongation factor Tu domain 2 IF2_N PF04760.10 KXX82379.1 - 5e-09 35.6 0.0 1.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 KXX82379.1 - 1.3e-07 31.5 0.1 3.6e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX82379.1 - 6.1e-07 29.9 0.1 1.4e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KXX82379.1 - 1.2e-06 28.0 0.3 3.3e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KXX82379.1 - 2.2e-06 27.0 0.0 4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 KXX82379.1 - 6.1e-06 25.5 0.1 1.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KXX82379.1 - 0.00022 20.4 0.3 0.00081 18.6 0.2 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 KXX82379.1 - 0.002 16.9 0.8 0.0086 14.8 0.4 2.1 1 1 1 2 2 2 1 ArgK protein GTP_EFTU_D4 PF14578.1 KXX82379.1 - 0.025 14.2 6.6 0.52 9.9 1.4 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 KXX82379.1 - 0.062 13.1 4.1 1.9 8.3 0.0 3.0 3 1 1 4 4 4 0 Dynamin family DUF367 PF04034.8 KXX82380.1 - 3.4e-47 159.2 0.0 4.6e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KXX82380.1 - 2.8e-12 46.0 0.7 5.7e-12 45.0 0.5 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Polyoma_lg_T_C PF06431.6 KXX82380.1 - 0.35 9.4 0.7 0.61 8.6 0.5 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus SDA1 PF05285.7 KXX82380.1 - 10 5.3 17.6 16 4.6 12.2 1.3 1 0 0 1 1 1 0 SDA1 VHS PF00790.14 KXX82381.1 - 2e-44 150.6 0.0 7.5e-44 148.7 0.0 2.0 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 KXX82381.1 - 3.7e-24 84.6 0.2 8.7e-24 83.4 0.2 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KXX82381.1 - 3.2e-22 79.0 5.8 3.9e-21 75.4 0.0 2.8 3 0 0 3 3 3 1 Adaptin C-terminal domain ChiC PF06483.6 KXX82381.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Chitinase C Transglut_C PF00927.17 KXX82381.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain AAA_16 PF13191.1 KXX82382.1 - 8.5e-08 32.3 0.1 4.6e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KXX82382.1 - 2.1e-06 26.7 0.0 5.4e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain DUF676 PF05057.9 KXX82382.1 - 1.2e-05 24.7 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 KXX82382.1 - 0.034 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.8 KXX82382.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RuvB_N PF05496.7 KXX82382.1 - 0.15 11.0 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FHA PF00498.21 KXX82383.1 - 1.1e-15 57.4 0.0 2.5e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 KXX82383.1 - 1.9 6.8 29.6 2.4 6.5 20.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CoA_trans PF01144.18 KXX82384.1 - 2.7e-97 324.1 0.5 4.7e-56 189.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KXX82384.1 - 0.00028 20.5 0.3 0.00053 19.6 0.2 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1737 PF08410.5 KXX82386.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Terpene_synth_C PF03936.11 KXX82387.1 - 0.0027 16.9 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HTH_24 PF13412.1 KXX82387.1 - 0.13 11.6 0.0 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MARVEL PF01284.18 KXX82388.1 - 0.007 16.1 20.5 0.013 15.3 14.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KXX82388.1 - 0.19 11.3 16.7 0.56 9.8 7.9 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4293 PF14126.1 KXX82388.1 - 1.7 8.5 5.5 0.5 10.2 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF1129 PF06570.6 KXX82388.1 - 7 5.9 8.7 2.1 7.5 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3129 PF11327.3 KXX82389.1 - 2.2e-18 66.7 4.7 2.8e-15 56.5 0.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3129) Xan_ur_permease PF00860.15 KXX82390.1 - 2.2e-65 220.6 32.7 3.9e-64 216.5 22.7 2.0 1 1 0 1 1 1 1 Permease family CorA PF01544.13 KXX82390.1 - 0.43 9.5 0.5 0.8 8.6 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mito_carr PF00153.22 KXX82392.1 - 2.9e-46 155.0 4.2 5.7e-16 57.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 KXX82393.1 - 5.9e-06 26.0 8.1 1.1e-05 25.2 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX82393.1 - 0.014 14.2 0.0 0.039 12.8 0.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain PROL5-SMR PF15621.1 KXX82393.1 - 0.12 12.8 0.3 0.29 11.5 0.2 1.6 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family HET PF06985.6 KXX82394.1 - 6.3e-30 104.1 0.0 9.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF981 PF06168.6 KXX82395.1 - 0.0087 15.8 2.5 0.011 15.4 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF981) DUF2517 PF10725.4 KXX82395.1 - 0.049 13.3 0.2 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) IBR PF01485.16 KXX82396.1 - 3.3e-22 78.1 45.5 6.6e-12 45.1 4.7 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KXX82396.1 - 3.2e-05 23.8 7.9 3.2e-05 23.8 5.5 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX82396.1 - 3.5e-05 23.3 42.4 0.00045 19.8 3.7 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX82396.1 - 0.003 17.3 7.0 0.003 17.3 4.9 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 KXX82396.1 - 3.8 7.3 43.1 0.067 12.9 5.6 3.8 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KXX82396.1 - 4 7.3 33.6 0.99 9.3 3.2 4.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING CoA_trans PF01144.18 KXX82397.1 - 5.8e-99 329.6 0.6 1.1e-58 197.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KXX82397.1 - 0.0035 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SprT-like PF10263.4 KXX82398.1 - 3.7e-48 163.1 3.6 7e-48 162.2 2.0 1.8 1 1 0 1 1 1 1 SprT-like family HMG_box PF00505.14 KXX82398.1 - 0.00025 21.2 0.1 0.0012 19.1 0.0 2.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX82398.1 - 0.005 17.1 1.0 0.015 15.6 0.1 2.3 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 KXX82398.1 - 0.0082 16.3 0.4 0.028 14.6 0.3 1.9 1 0 0 1 1 1 1 YABBY protein CHDNT PF08073.7 KXX82398.1 - 0.01 15.4 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain Peptidase_MA_2 PF13485.1 KXX82398.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M50B PF13398.1 KXX82398.1 - 0.32 10.3 0.1 0.55 9.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DASH_Dam1 PF08653.5 KXX82399.1 - 4.6e-27 93.5 1.6 4.6e-27 93.5 1.1 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 Mog1 PF04603.7 KXX82400.1 - 2.7e-20 72.7 0.0 3.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.18 KXX82401.1 - 9.7e-21 74.1 0.2 1.5e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KXX82401.1 - 7.5e-12 45.5 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KXX82401.1 - 8.4e-05 22.2 0.1 0.00013 21.5 0.1 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF167 PF02594.11 KXX82402.1 - 5.4e-19 67.8 0.2 6.8e-19 67.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 GRIP PF01465.15 KXX82402.1 - 0.06 12.8 0.1 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 GRIP domain Redoxin PF08534.5 KXX82403.1 - 1.4e-28 99.3 0.0 1.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KXX82403.1 - 3.2e-08 33.2 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glucan_synthase PF02364.10 KXX82404.1 - 0 1415.3 0.0 0 1414.5 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KXX82404.1 - 2.9e-40 136.8 0.4 6.7e-40 135.6 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CRAL_TRIO PF00650.15 KXX82405.1 - 2.2e-46 157.2 0.1 3.6e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KXX82405.1 - 9.8e-14 51.5 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KXX82405.1 - 2.5e-13 49.9 0.2 9.8e-13 48.0 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain F_bP_aldolase PF01116.15 KXX82406.1 - 3.4e-95 318.4 0.0 3.8e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF2973 PF11189.3 KXX82406.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Aminotran_1_2 PF00155.16 KXX82407.1 - 1.7e-39 135.8 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KXX82407.1 - 0.0074 14.6 0.0 0.012 13.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KXX82407.1 - 0.018 13.5 0.0 0.071 11.6 0.0 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain MFS_1 PF07690.11 KXX82408.1 - 1.7e-41 142.1 76.8 6.9e-31 107.2 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82408.1 - 2e-14 53.0 32.3 9.3e-09 34.3 8.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KXX82408.1 - 6.8e-08 31.3 8.6 6.8e-08 31.3 5.9 2.1 1 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KXX82408.1 - 0.00054 19.7 2.8 0.39 10.5 0.2 2.7 2 0 0 2 2 2 2 MFS_1 like family MutS_V PF00488.16 KXX82409.1 - 1.4e-80 270.1 0.0 2.3e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KXX82409.1 - 8e-50 169.4 0.1 1.4e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KXX82409.1 - 3.3e-32 110.8 0.1 1.1e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KXX82409.1 - 9.4e-14 51.6 0.0 5.9e-13 49.0 0.0 2.4 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KXX82409.1 - 8.3e-13 48.3 1.0 1.7e-12 47.3 0.7 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KXX82409.1 - 0.003 17.9 0.3 0.003 17.9 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KXX82409.1 - 0.013 14.9 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KXX82409.1 - 0.078 12.9 2.7 0.082 12.8 0.2 2.3 3 0 0 3 3 3 0 AAA domain Ribonuc_red_2_N PF08471.5 KXX82409.1 - 0.11 12.5 0.2 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Mating_N PF12731.2 KXX82410.1 - 0.11 12.4 0.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 Clr5 PF14420.1 KXX82411.1 - 1.8e-10 40.5 0.0 8.5e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Clr5 domain Cu-oxidase_4 PF02578.10 KXX82412.1 - 8.1e-25 87.2 0.0 1.7e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase TSCPD PF12637.2 KXX82413.1 - 0.074 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 TSCPD domain UPF0197 PF05251.7 KXX82413.1 - 0.22 11.8 3.3 1.1 9.5 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) Diphthamide_syn PF01866.12 KXX82414.1 - 2.2e-52 178.2 0.0 2.4e-51 174.8 0.0 1.9 2 0 0 2 2 2 1 Putative diphthamide synthesis protein SET PF00856.23 KXX82415.1 - 7.5e-10 39.3 0.1 1.2e-08 35.4 0.1 2.4 1 1 0 1 1 1 1 SET domain NTNH_C PF08470.5 KXX82415.1 - 0.064 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal SAF PF08666.7 KXX82415.1 - 0.069 13.5 0.1 0.75 10.2 0.0 2.2 2 0 0 2 2 2 0 SAF domain Fasciclin PF02469.17 KXX82416.1 - 1.5e-41 141.3 0.2 2.8e-25 88.7 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Peptidase_C12 PF01088.16 KXX82417.1 - 3.2e-46 157.2 0.0 4e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TPR_17 PF13431.1 KXX82417.1 - 0.025 14.7 0.0 8 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CP2 PF04516.10 KXX82419.1 - 2.7e-85 285.1 0.0 4.2e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 KXX82419.1 - 0.02 14.5 0.1 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Major spike protein (G protein) Tektin PF03148.9 KXX82419.1 - 0.023 13.2 0.0 0.033 12.7 0.0 1.1 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.3 KXX82419.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CG-1 PF03859.11 KXX82419.1 - 0.13 11.7 0.5 1 8.8 0.0 2.4 3 0 0 3 3 3 0 CG-1 domain Oxysterol_BP PF01237.13 KXX82420.1 - 3.7e-54 183.5 0.0 9e-44 149.3 0.0 2.3 2 1 0 2 2 2 2 Oxysterol-binding protein eIF2A PF08662.6 KXX82421.1 - 2.3e-76 255.8 0.0 1.3e-75 253.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KXX82421.1 - 0.00058 19.6 0.9 3.9 7.5 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 KXX82421.1 - 0.014 15.4 0.5 0.014 15.4 0.4 2.5 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 Peptidase_A21 PF03566.8 KXX82421.1 - 4.1 5.3 9.4 8 4.4 4.7 2.0 2 0 0 2 2 2 0 Peptidase family A21 PAF-AH_p_II PF03403.8 KXX82422.1 - 7.1e-38 129.8 0.0 8.2e-33 113.2 0.0 2.0 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KXX82422.1 - 6.4e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82422.1 - 5.5e-10 39.5 0.2 2e-09 37.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KXX82422.1 - 0.00046 19.1 0.1 0.0042 16.0 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KXX82422.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 KXX82422.1 - 0.041 12.6 0.1 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase WD40_alt PF14077.1 KXX82422.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Transformer PF06495.6 KXX82423.1 - 0.09 12.6 12.7 0.066 13.0 3.8 2.4 2 0 0 2 2 2 0 Fruit fly transformer protein Corona_nucleoca PF00937.13 KXX82423.1 - 0.42 9.5 14.1 1.5 7.6 5.7 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 KXX82423.1 - 1.4 8.1 13.9 2.4 7.3 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) MFS_1 PF07690.11 KXX82424.1 - 2.6e-33 115.1 22.5 2.6e-33 115.1 15.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sars6 PF12133.3 KXX82424.1 - 0.086 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus LIP PF03583.9 KXX82425.1 - 5e-47 160.4 0.0 1.5e-22 80.1 0.0 3.0 3 0 0 3 3 3 3 Secretory lipase Abhydrolase_5 PF12695.2 KXX82425.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KXX82425.1 - 0.16 11.1 0.0 9.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family p450 PF00067.17 KXX82427.1 - 4e-48 164.0 0.0 4.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.14 KXX82428.1 - 2e-33 114.1 31.1 3.5e-18 65.3 5.3 4.6 2 1 1 3 3 3 3 WSC domain Amidase PF01425.16 KXX82429.1 - 4.7e-87 292.6 0.0 5.8e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.17 KXX82430.1 - 2.8e-12 45.9 0.0 3.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 gag_pre-integrs PF13976.1 KXX82431.1 - 0.00096 18.7 0.0 0.00096 18.7 0.0 2.3 2 1 1 3 3 3 1 GAG-pre-integrase domain FYVE PF01363.16 KXX82431.1 - 0.0053 16.6 0.9 0.0053 16.6 0.6 1.8 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.2 KXX82431.1 - 0.0056 16.4 3.2 0.047 13.5 0.6 2.4 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KXX82431.1 - 7.1 5.9 10.1 0.45 9.7 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF848 PF05852.6 KXX82432.1 - 0.015 15.1 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) UBN2 PF14223.1 KXX82432.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 KXX82433.1 - 2.4e-53 180.6 0.0 3.2e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KXX82433.1 - 0.013 14.8 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.13 KXX82435.1 - 5.1e-56 189.9 4.9 5.8e-56 189.7 3.4 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tcp11 PF05794.8 KXX82436.1 - 1.6e-43 149.1 1.3 2.2e-43 148.5 0.0 1.7 2 0 0 2 2 2 1 T-complex protein 11 DUF4170 PF13773.1 KXX82436.1 - 0.72 9.8 2.4 23 4.9 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) Fringe PF02434.11 KXX82437.1 - 2.2e-06 27.0 2.5 2.8e-05 23.4 1.7 2.3 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 KXX82437.1 - 0.035 13.7 0.2 0.088 12.3 0.1 1.7 1 1 0 1 1 1 0 Galactosyltransferase DUF604 PF04646.7 KXX82437.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 PEPcase_2 PF14010.1 KXX82438.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Methyltransf_23 PF13489.1 KXX82439.1 - 8.2e-24 84.1 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82439.1 - 8.3e-10 39.2 0.0 1.1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82439.1 - 3.7e-08 33.7 0.0 2.3e-07 31.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82439.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82439.1 - 4.6e-07 29.5 0.0 3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82439.1 - 9.7e-07 29.0 0.0 2.9e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX82439.1 - 0.0024 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KXX82439.1 - 0.0037 16.6 0.0 0.021 14.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KXX82439.1 - 0.014 15.4 0.0 0.051 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KXX82439.1 - 0.054 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ank_2 PF12796.2 KXX82440.1 - 6.3e-14 52.0 0.0 2.6e-07 30.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX82440.1 - 3.4e-13 49.3 0.5 4.5e-06 26.7 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX82440.1 - 2.5e-11 43.7 0.8 0.054 14.0 0.0 4.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KXX82440.1 - 7.5e-10 38.1 0.8 3.8e-05 23.2 0.1 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 KXX82440.1 - 4.3e-07 29.5 1.4 0.00049 20.0 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat Oxysterol_BP PF01237.13 KXX82441.1 - 6.6e-65 218.9 0.0 9.5e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein FAD-oxidase_C PF02913.14 KXX82442.1 - 4.7e-57 193.1 0.0 7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KXX82442.1 - 3.7e-39 133.3 0.0 7.2e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AMP-binding PF00501.23 KXX82443.1 - 5e-79 265.6 0.0 7.8e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KXX82443.1 - 5.4e-79 265.2 0.0 9.6e-79 264.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX82443.1 - 2.2e-53 180.5 0.0 1.2e-51 174.9 0.0 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KXX82443.1 - 3.2e-48 164.7 0.2 6.2e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX82443.1 - 1.6e-47 162.1 0.0 3.1e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX82443.1 - 2.3e-45 154.4 0.0 2.3e-42 144.7 0.0 3.1 2 0 0 2 2 2 1 short chain dehydrogenase Condensation PF00668.15 KXX82443.1 - 2.2e-44 151.5 0.3 4e-44 150.6 0.2 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KXX82443.1 - 1.2e-30 106.2 0.0 2.9e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KXX82443.1 - 1.8e-28 98.7 0.0 4e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX82443.1 - 1.5e-16 60.6 0.0 8.5e-16 58.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KXX82443.1 - 4.4e-12 46.0 3.3 3.1e-05 24.1 0.1 3.7 4 0 0 4 4 3 2 Phosphopantetheine attachment site Epimerase PF01370.16 KXX82443.1 - 3.4e-11 43.0 0.0 5.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KXX82443.1 - 1e-09 38.7 0.0 4.2e-09 36.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KXX82443.1 - 4.2e-09 36.5 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KXX82443.1 - 4.9e-08 33.1 0.0 6.9e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_23 PF13489.1 KXX82443.1 - 6.8e-08 32.4 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82443.1 - 8.8e-06 26.2 0.0 4.5e-05 23.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82443.1 - 1.2e-05 24.9 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KXX82443.1 - 7.1e-05 21.9 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KXX82443.1 - 0.00076 18.2 0.0 0.063 11.9 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KXX82443.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NmrA PF05368.8 KXX82443.1 - 0.031 13.5 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family Rhabdo_ncap PF00945.13 KXX82443.1 - 0.33 9.5 0.0 0.56 8.7 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF1681 PF07933.9 KXX82443.1 - 0.34 10.4 0.0 9.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Fungal_trans PF04082.13 KXX82445.1 - 3.2e-17 62.2 0.0 5.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 KXX82445.1 - 0.96 7.6 8.9 1.4 7.0 6.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADH_zinc_N PF00107.21 KXX82446.1 - 8e-07 28.6 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KXX82446.1 - 2.9e-05 23.7 0.1 6.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain K_oxygenase PF13434.1 KXX82447.1 - 1.5e-12 47.0 0.0 1.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KXX82447.1 - 1.9e-09 37.9 0.0 0.0026 17.8 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX82447.1 - 1.1e-05 25.3 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX82447.1 - 0.0013 18.6 0.0 0.027 14.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase VirE2 PF07229.7 KXX82447.1 - 0.0032 15.9 0.0 0.0066 14.9 0.0 1.4 1 1 1 2 2 2 1 VirE2 FAD_binding_3 PF01494.14 KXX82447.1 - 0.0036 16.4 0.1 0.063 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KXX82447.1 - 0.0053 15.7 0.0 0.011 14.6 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KXX82447.1 - 0.014 15.3 0.2 0.072 13.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX82447.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KXX82447.1 - 0.043 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KXX82447.1 - 0.063 13.6 0.5 18 5.7 0.1 3.3 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX82447.1 - 0.067 11.6 0.0 0.31 9.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 KXX82447.1 - 0.084 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KXX82447.1 - 0.089 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 KXX82447.1 - 0.42 9.4 6.1 1 8.1 1.0 2.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 KXX82448.1 - 2.6e-08 33.9 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HTH_AsnC-type PF13404.1 KXX82448.1 - 0.0007 19.0 0.1 0.0024 17.3 0.0 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain KR PF08659.5 KXX82448.1 - 0.044 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 KXX82448.1 - 0.07 12.9 0.4 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.1 KXX82449.1 - 5.1e-18 65.3 0.0 9.1e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FA_hydroxylase PF04116.8 KXX82449.1 - 2.6e-17 63.2 14.7 6.8e-17 61.9 10.2 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Methyltransf_31 PF13847.1 KXX82449.1 - 7.2e-09 35.4 0.0 2.4e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82449.1 - 3.9e-06 27.3 0.0 2.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82449.1 - 0.0021 18.4 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX82449.1 - 0.18 11.1 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain GFO_IDH_MocA_C PF02894.12 KXX82450.1 - 7.6e-17 61.1 0.1 2.3e-16 59.6 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 KXX82450.1 - 1e-14 55.0 0.0 1.8e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 KXX82451.1 - 1.8e-27 96.0 28.6 1.8e-27 96.0 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KXX82452.1 - 3e-45 154.4 42.7 3e-45 154.4 29.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82452.1 - 6e-10 38.2 32.8 3e-09 35.9 22.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KXX82452.1 - 0.00081 17.6 8.5 0.00081 17.6 5.9 2.6 2 1 1 3 3 3 1 Transmembrane secretion effector adh_short PF00106.20 KXX82454.1 - 1.6e-13 50.9 0.1 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82454.1 - 9.8e-09 35.1 0.1 2.3e-08 33.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX82454.1 - 1.1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNA_pol_Rpb6 PF01192.17 KXX82454.1 - 0.00098 18.8 1.8 0.0067 16.1 0.1 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb6 Saccharop_dh PF03435.13 KXX82454.1 - 0.0074 15.3 0.2 0.04 12.8 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KXX82454.1 - 0.046 13.8 0.2 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KXX82454.1 - 0.047 12.8 0.1 0.084 12.0 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KXX82454.1 - 0.05 12.4 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 KXX82454.1 - 0.091 11.8 0.1 0.29 10.2 0.0 1.8 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.11 KXX82455.1 - 1.5e-25 89.6 35.5 3.8e-24 85.0 22.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82455.1 - 0.0001 21.0 7.4 0.0001 21.0 5.1 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter YqjK PF13997.1 KXX82455.1 - 0.00019 21.5 0.2 1.1 9.5 0.2 2.5 2 0 0 2 2 2 2 YqjK-like protein Cad PF03596.8 KXX82455.1 - 0.0047 16.6 0.1 7.9 6.1 0.0 3.2 2 1 1 3 3 3 2 Cadmium resistance transporter CorA PF01544.13 KXX82456.1 - 6.7e-09 35.1 0.2 6.7e-09 35.1 0.1 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Ammonium_transp PF00909.16 KXX82456.1 - 0.036 12.5 1.6 0.047 12.1 1.1 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family SLAC1 PF03595.12 KXX82457.1 - 1.1e-68 231.3 44.8 1.3e-68 231.1 31.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel FAD_binding_3 PF01494.14 KXX82458.1 - 4e-16 59.0 0.0 1e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX82458.1 - 3.2e-08 32.8 0.0 0.00042 19.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX82458.1 - 2.9e-05 24.3 0.0 0.013 15.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KXX82458.1 - 0.0014 17.3 0.0 0.25 9.9 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KXX82458.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 KXX82458.1 - 0.23 10.2 0.0 1.7 7.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase DUF3429 PF11911.3 KXX82459.1 - 5.5e-40 136.6 9.6 7.3e-40 136.2 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.5 KXX82459.1 - 0.035 13.8 4.6 0.071 12.9 3.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Transgly_assoc PF04226.8 KXX82459.1 - 0.064 13.3 2.0 0.38 10.8 0.2 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4220 PF13968.1 KXX82459.1 - 0.19 10.7 0.3 0.27 10.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4337 PF14235.1 KXX82459.1 - 8.7 6.1 13.7 17 5.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1162 PF06650.7 KXX82464.1 - 7.8e-82 274.5 0.0 4.3e-80 268.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KXX82464.1 - 1.6e-41 140.5 0.1 5e-41 138.9 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KXX82464.1 - 4.9e-06 26.6 0.2 4.9e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain MFS_1 PF07690.11 KXX82466.1 - 3.1e-24 85.3 23.7 3.1e-24 85.3 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1966 PF09260.6 KXX82467.1 - 2.5e-13 49.8 0.3 5.7e-13 48.7 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Peptidase_M1 PF01433.15 KXX82468.1 - 1e-132 442.9 0.1 1.4e-132 442.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KXX82468.1 - 5.2e-74 249.4 0.0 3.6e-73 246.6 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KXX82468.1 - 1.6e-20 73.4 1.5 1.2e-19 70.6 0.1 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KXX82468.1 - 0.0038 17.0 0.1 0.013 15.2 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 KXX82468.1 - 0.032 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF1479 PF07350.7 KXX82469.1 - 3.7e-156 519.7 0.0 5e-156 519.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) FAD_binding_2 PF00890.19 KXX82470.1 - 7.8e-89 298.3 0.1 9e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KXX82470.1 - 4.3e-07 29.8 0.0 2.2e-06 27.6 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KXX82470.1 - 1.3e-05 24.2 0.1 1.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KXX82470.1 - 5.6e-05 21.7 0.9 0.0016 17.0 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KXX82470.1 - 5.8e-05 23.0 0.0 0.002 18.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KXX82470.1 - 8.4e-05 21.7 0.1 0.00033 19.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KXX82470.1 - 0.00012 21.1 0.3 0.00053 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KXX82470.1 - 0.00019 20.6 0.0 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX82470.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KXX82470.1 - 0.0021 17.2 0.0 0.0055 15.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX82470.1 - 0.0046 17.0 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX82470.1 - 0.025 13.5 0.2 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SAD_SRA PF02182.12 KXX82471.1 - 6e-25 87.3 0.1 9.3e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Sugar_tr PF00083.19 KXX82472.1 - 9.6e-103 344.1 33.6 1.2e-102 343.8 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX82472.1 - 2.6e-25 88.8 36.1 2.3e-22 79.2 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4394 PF14339.1 KXX82473.1 - 0.0024 17.1 0.9 3.6 6.8 0.0 3.3 2 1 0 3 3 3 2 Domain of unknown function (DUF4394) SGL PF08450.7 KXX82473.1 - 0.027 13.8 1.2 3.8 6.8 0.1 2.8 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KXX82473.1 - 0.17 11.9 3.2 12 6.0 0.0 3.0 3 0 0 3 3 3 0 NHL repeat NDUF_B7 PF05676.8 KXX82474.1 - 0.025 14.0 1.9 0.025 14.0 1.3 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Aldo_ket_red PF00248.16 KXX82475.1 - 5.7e-68 228.7 0.0 6.5e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2235 PF09994.4 KXX82476.1 - 1.2e-64 218.3 0.1 6.4e-37 127.4 0.0 2.1 1 1 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KXX82476.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family OHCU_decarbox PF09349.5 KXX82477.1 - 8.9e-44 149.5 0.4 1.1e-43 149.3 0.3 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Granin PF01271.12 KXX82477.1 - 0.071 11.8 5.5 0.085 11.5 3.8 1.1 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) GCV_T PF01571.16 KXX82477.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Methyltransf_23 PF13489.1 KXX82478.1 - 1.8e-19 70.0 0.0 2.6e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82478.1 - 6.4e-11 42.5 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82478.1 - 1.8e-07 31.5 0.0 2.3e-06 28.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82478.1 - 2.2e-06 27.3 0.0 1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82478.1 - 2.6e-06 27.9 0.0 1.8e-05 25.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82478.1 - 3.4e-06 26.3 0.0 2.7e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX82478.1 - 0.0005 20.3 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KXX82478.1 - 0.00074 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KXX82478.1 - 0.0074 16.3 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KXX82478.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 KXX82478.1 - 0.049 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PUL PF08324.6 KXX82478.1 - 0.051 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 PUL domain PrmA PF06325.8 KXX82478.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 KXX82479.1 - 4.5e-29 101.4 0.0 6.3e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 KXX82479.1 - 2.2e-08 34.4 0.0 3.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX82479.1 - 8.4e-08 32.0 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82479.1 - 1.5e-07 31.9 0.0 2.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82479.1 - 3.1e-07 30.7 0.0 2.2e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82479.1 - 2.7e-06 27.0 0.0 3.6e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX82479.1 - 9.6e-06 25.6 0.1 2.3e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82479.1 - 1.1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KXX82479.1 - 0.002 17.3 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KXX82479.1 - 0.038 13.6 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 KXX82479.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.9 KXX82479.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.2 KXX82480.1 - 3.1e-13 49.8 0.0 2.2e-06 27.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KXX82480.1 - 2.7e-12 46.4 0.3 1.7e-07 31.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX82480.1 - 4.5e-12 46.1 0.5 0.0001 22.7 0.0 5.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 KXX82480.1 - 4e-09 35.8 0.0 0.00098 18.8 0.0 4.7 4 2 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KXX82480.1 - 5.2e-08 32.3 0.8 0.0098 16.0 0.0 4.6 6 0 0 6 6 6 2 Ankyrin repeat CytochromB561_N PF09786.4 KXX82480.1 - 0.062 11.7 1.1 0.092 11.1 0.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal EthD PF07110.6 KXX82482.1 - 8.2e-05 23.4 0.0 0.00011 23.0 0.0 1.2 1 0 0 1 1 1 1 EthD domain Flavodoxin_4 PF12682.2 KXX82482.1 - 0.11 11.8 0.3 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Flavodoxin ADH_N PF08240.7 KXX82483.1 - 1.4e-27 95.5 4.2 2.3e-27 94.9 2.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX82483.1 - 2.3e-16 59.5 0.0 3.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX82483.1 - 0.0013 19.5 0.0 0.0024 18.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KXX82483.1 - 0.0027 16.8 0.2 0.0088 15.2 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KXX82483.1 - 0.029 13.9 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Chs3p PF12271.3 KXX82484.1 - 1.3e-139 464.2 14.2 1.5e-139 464.0 9.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KXX82484.1 - 7.4 6.5 13.2 0.16 11.9 2.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Cyclin PF08613.6 KXX82485.1 - 2.1e-13 50.9 0.0 3.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KXX82485.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Aldo_ket_red PF00248.16 KXX82486.1 - 2.1e-43 148.1 0.0 3e-35 121.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Fungal_trans PF04082.13 KXX82487.1 - 3.5e-23 81.8 1.9 6.1e-23 81.0 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82487.1 - 7.6e-08 32.1 11.6 1.5e-07 31.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 KXX82487.1 - 0.14 12.1 0.8 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 PocR PF10114.4 KXX82487.1 - 0.24 10.5 2.2 0.39 9.8 1.5 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR Pox_A_type_inc PF04508.7 KXX82487.1 - 0.4 10.5 5.1 1 9.2 3.6 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat p450 PF00067.17 KXX82488.1 - 1.6e-53 181.9 0.0 1.5e-38 132.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SnoaL_4 PF13577.1 KXX82489.1 - 7.6e-09 35.5 0.0 2.3e-08 34.0 0.0 1.8 1 1 1 2 2 2 1 SnoaL-like domain Reo_sigmaC PF04582.7 KXX82490.1 - 1.8e-09 37.2 36.2 0.0012 18.0 3.2 5.4 1 1 2 5 5 5 3 Reovirus sigma C capsid protein Filament PF00038.16 KXX82490.1 - 6e-07 29.2 94.0 5.1e-05 22.9 8.5 3.7 1 1 2 3 3 3 2 Intermediate filament protein Cortex-I_coil PF09304.5 KXX82490.1 - 7.7e-07 29.1 21.3 8.4e-05 22.5 6.8 8.1 2 2 4 7 7 6 3 Cortexillin I, coiled coil CENP-F_leu_zip PF10473.4 KXX82490.1 - 2.8e-06 27.2 99.5 3.2e-06 27.0 3.1 7.4 1 1 7 8 8 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KXX82490.1 - 1.4e-05 23.7 9.5 1.4e-05 23.7 6.6 4.1 2 1 2 4 4 4 3 AAA domain Myosin_tail_1 PF01576.14 KXX82490.1 - 5.6e-05 21.0 18.8 5.6e-05 21.0 13.0 2.1 1 1 1 2 2 2 2 Myosin tail CCDC155 PF14662.1 KXX82490.1 - 0.00014 21.5 7.8 0.00014 21.5 5.4 5.8 2 2 2 6 6 5 1 Coiled-coil region of CCDC155 IncA PF04156.9 KXX82490.1 - 0.00034 20.2 106.6 0.00089 18.9 11.1 7.3 1 1 5 6 6 5 4 IncA protein APG6 PF04111.7 KXX82490.1 - 0.0012 17.9 5.4 0.0012 17.9 3.7 6.4 1 1 5 6 6 6 3 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KXX82490.1 - 0.0044 16.8 6.8 0.0044 16.8 4.7 7.0 2 2 1 5 5 4 2 Tropomyosin like DUF3584 PF12128.3 KXX82490.1 - 0.029 11.7 103.6 0.008 13.5 19.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Med9 PF07544.8 KXX82490.1 - 0.03 14.0 0.7 0.03 14.0 0.5 8.4 4 3 7 11 11 11 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 KXX82490.1 - 0.039 13.7 39.1 0.75 9.6 1.1 6.8 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KXX82490.1 - 0.75 8.3 86.1 0.056 12.1 3.8 5.9 1 1 5 7 7 6 0 Spc7 kinetochore protein GIT_SHD PF08518.6 KXX82492.1 - 2.1e-08 33.3 0.6 6.6e-08 31.7 0.4 1.9 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT DUF1338 PF07063.8 KXX82492.1 - 0.026 13.6 0.8 1.5 7.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) DUF3435 PF11917.3 KXX82493.1 - 0.0064 15.2 2.0 0.0087 14.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Vps54 PF07928.7 KXX82495.1 - 1.1e-21 77.4 0.4 1.1e-19 70.8 0.1 3.2 2 1 1 3 3 3 2 Vps54-like protein DUF2450 PF10475.4 KXX82495.1 - 0.0089 14.9 0.4 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) MFS_1 PF07690.11 KXX82496.1 - 4.8e-38 130.7 57.8 8.5e-38 129.9 38.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82496.1 - 4.2e-08 32.2 11.1 4.2e-08 32.2 7.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Corona_S2 PF01601.11 KXX82496.1 - 0.063 11.3 2.6 0.1 10.7 1.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein P2_Phage_GpR PF06891.6 KXX82497.1 - 0.067 12.9 1.2 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) Ctr PF04145.10 KXX82498.1 - 1.3e-43 148.5 1.1 1.5e-43 148.2 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.5 KXX82498.1 - 4.3 5.2 11.2 3.7 5.4 5.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.7 KXX82499.1 - 3.6e-102 341.4 0.0 4.7e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF3716 PF12511.3 KXX82500.1 - 3.1e-10 39.4 4.0 5.5e-10 38.7 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3355 PF11835.3 KXX82500.1 - 0.01 15.6 2.0 0.031 14.0 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) UBN2 PF14223.1 KXX82500.1 - 1.4 8.7 4.2 1.2 8.9 1.1 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4407 PF14362.1 KXX82500.1 - 3 6.6 6.1 5.8 5.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_S6 PF01250.12 KXX82501.1 - 1e-06 28.5 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Arrestin_C PF02752.17 KXX82502.1 - 2.9e-16 59.7 0.0 1.1e-15 57.9 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KXX82502.1 - 3.6e-10 39.8 1.9 3.2e-06 27.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Nucleocapsid-N PF11030.3 KXX82502.1 - 0.097 12.4 3.4 0.22 11.3 2.4 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N SurE PF01975.12 KXX82503.1 - 3.7e-28 98.1 0.2 5e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Fungal_trans PF04082.13 KXX82504.1 - 9.2e-10 37.8 0.7 1.6e-09 37.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82504.1 - 0.0037 17.1 10.6 0.0059 16.4 0.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2_2 PF01799.15 KXX82504.1 - 0.096 12.5 0.5 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 [2Fe-2S] binding domain SNARE_assoc PF09335.6 KXX82505.1 - 0.002 18.3 0.3 0.0023 18.1 0.2 1.1 1 0 0 1 1 1 1 SNARE associated Golgi protein Adeno_E3_CR2 PF02439.10 KXX82505.1 - 0.027 14.0 4.6 0.051 13.1 3.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SCIMP PF15050.1 KXX82505.1 - 0.048 13.5 0.1 0.055 13.3 0.1 1.1 1 0 0 1 1 1 0 SCIMP protein MtrF PF09472.5 KXX82505.1 - 0.059 12.6 0.3 0.093 11.9 0.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) LRR19-TM PF15176.1 KXX82505.1 - 0.069 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain MLANA PF14991.1 KXX82505.1 - 0.11 12.4 0.1 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A DUF2102 PF09875.4 KXX82505.1 - 0.11 11.9 0.6 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Fungal_trans_2 PF11951.3 KXX82506.1 - 7.8e-27 93.8 0.8 1.1e-26 93.4 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82506.1 - 3.3e-07 30.0 8.0 5.7e-07 29.3 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin PF00085.15 KXX82507.1 - 1.1e-26 92.5 0.0 1.3e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KXX82507.1 - 2.7e-07 30.7 0.1 6.5e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KXX82507.1 - 2.4e-05 24.3 0.0 0.0018 18.3 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 KXX82507.1 - 0.0009 18.9 0.1 0.044 13.4 0.0 2.1 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KXX82507.1 - 0.0029 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KXX82507.1 - 0.021 14.3 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 KXX82507.1 - 0.023 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 KXX82507.1 - 0.038 13.4 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 PX PF00787.19 KXX82509.1 - 2.6e-18 65.8 0.1 5.2e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.10 KXX82510.1 - 2.8e-26 91.9 4.7 4.5e-26 91.2 3.2 1.3 1 0 0 1 1 1 1 Cullin binding Peptidase_S8 PF00082.17 KXX82512.1 - 6.7e-11 41.8 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 KXX82513.1 - 2.8e-81 267.9 14.8 3.4e-16 59.3 0.3 6.7 1 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82513.1 - 2.9e-48 159.3 40.5 0.0041 16.8 0.2 15.4 16 0 0 16 16 15 13 Ankyrin repeat Ank_4 PF13637.1 KXX82513.1 - 4.5e-34 116.2 12.3 1.3e-06 28.7 0.0 10.7 5 1 7 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82513.1 - 1.9e-30 101.8 16.6 0.011 15.8 0.0 15.1 15 0 0 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 KXX82513.1 - 3.1e-18 65.3 31.6 0.077 13.2 0.0 12.3 6 3 8 14 14 13 8 Ankyrin repeats (many copies) AAA_16 PF13191.1 KXX82513.1 - 8.9e-07 29.0 0.1 3.9e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX82513.1 - 1.4e-06 28.4 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KXX82513.1 - 8.3e-05 22.3 0.4 0.00021 20.9 0.3 1.7 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 KXX82513.1 - 0.0013 17.8 0.0 0.054 12.4 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain UBA PF00627.26 KXX82513.1 - 0.056 13.2 0.1 0.056 13.2 0.0 3.8 4 0 0 4 4 4 0 UBA/TS-N domain AAA_5 PF07728.9 KXX82513.1 - 0.093 12.4 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.9 KXX82513.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase LIM PF00412.17 KXX82513.1 - 0.3 11.1 0.5 0.63 10.1 0.3 1.5 1 0 0 1 1 1 0 LIM domain zinc_ribbon_2 PF13240.1 KXX82513.1 - 7 6.2 4.8 0.78 9.3 0.1 1.9 2 0 0 2 2 1 0 zinc-ribbon domain Ribosomal_L18e PF00828.14 KXX82514.1 - 3.4e-15 56.5 0.1 5.6e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GST_N PF02798.15 KXX82515.1 - 1.8e-10 40.8 0.0 5.3e-10 39.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KXX82515.1 - 2.1e-08 33.9 0.0 3.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX82515.1 - 3.2e-08 33.6 0.0 2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX82515.1 - 3.5e-08 33.3 0.0 9.9e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KXX82515.1 - 2.9e-07 30.8 0.0 4.5e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KXX82515.1 - 5.7e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 KXX82516.1 - 5.3e-65 219.7 0.0 6.7e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KXX82517.1 - 7.1e-25 87.6 0.1 3.3e-19 69.0 0.0 2.5 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KXX82517.1 - 1.9e-07 31.2 0.1 2.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KXX82517.1 - 0.011 15.6 0.7 0.011 15.6 0.5 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KXX82517.1 - 0.057 13.7 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KXX82518.1 - 5.2e-21 75.0 0.1 8.6e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82518.1 - 3.7e-10 39.6 0.0 1.1e-08 34.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82518.1 - 1.7e-09 38.0 0.0 7.8e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82518.1 - 2.2e-09 37.6 0.0 6.2e-09 36.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82518.1 - 1.3e-08 35.4 0.0 2.1e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82518.1 - 5.2e-06 26.7 0.0 1.4e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX82518.1 - 0.00011 22.2 0.0 0.00049 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KXX82518.1 - 0.00019 20.5 0.0 0.00059 18.9 0.0 1.7 2 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KXX82518.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KXX82518.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 KXX82518.1 - 0.016 14.2 0.0 0.037 13.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KXX82518.1 - 0.019 14.1 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KXX82518.1 - 0.052 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KXX82518.1 - 0.09 11.8 0.0 0.67 9.0 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Osmo_MPGsynth PF09488.5 KXX82519.1 - 2e-121 405.2 0.0 3e-121 404.6 0.0 1.2 1 1 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) EHN PF06441.7 KXX82521.1 - 1.3e-30 105.5 0.0 2.3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KXX82521.1 - 3.5e-09 36.9 2.2 6.6e-09 35.9 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82521.1 - 2.5e-06 27.2 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAM2 PF07145.10 KXX82523.1 - 0.012 15.0 0.5 0.012 15.0 0.3 1.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region NAD_binding_10 PF13460.1 KXX82524.1 - 4.5e-14 52.8 0.0 8.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KXX82524.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ACC_epsilon PF13822.1 KXX82524.1 - 0.16 12.3 1.1 14 6.1 0.5 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Abhydrolase_5 PF12695.2 KXX82525.1 - 2.7e-16 59.6 0.1 3.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82525.1 - 1.3e-09 38.3 3.8 6.2e-06 26.2 2.3 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82525.1 - 5.2e-05 22.9 0.2 0.00042 19.9 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KXX82525.1 - 0.00014 21.2 0.4 0.00022 20.5 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KXX82525.1 - 0.00046 19.4 0.6 0.11 11.6 0.4 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KXX82525.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 KXX82525.1 - 0.17 10.2 0.1 0.32 9.4 0.1 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FAD_binding_3 PF01494.14 KXX82526.1 - 1.2e-76 258.0 0.0 1.6e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KXX82526.1 - 9e-48 162.0 0.0 1.4e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KXX82526.1 - 0.0002 20.5 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KXX82526.1 - 0.00031 19.7 0.1 0.0085 15.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX82526.1 - 0.0023 16.8 0.0 0.0068 15.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KXX82526.1 - 0.0068 15.5 0.1 0.012 14.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX82526.1 - 0.012 15.6 0.1 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KXX82526.1 - 0.021 14.7 0.1 0.052 13.4 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNN_linker PF09050.5 KXX82526.1 - 0.04 13.4 1.2 0.1 12.1 0.8 1.7 1 0 0 1 1 1 0 Stannin unstructured linker SE PF08491.5 KXX82526.1 - 0.055 12.2 0.0 0.26 10.1 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 KXX82526.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KXX82526.1 - 0.11 12.9 0.1 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PP2C PF00481.16 KXX82527.1 - 1e-35 123.3 0.0 3e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KXX82527.1 - 0.00083 18.8 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KXX82527.1 - 0.022 14.4 0.1 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) RRM_1 PF00076.17 KXX82528.1 - 1.5e-42 143.0 1.4 7.5e-20 70.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX82528.1 - 8.9e-34 115.2 0.3 3.1e-18 65.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KXX82528.1 - 1.4e-30 105.3 0.1 3.2e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KXX82528.1 - 6.9e-20 70.6 0.1 1.7e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KXX82528.1 - 0.0042 16.9 0.8 0.087 12.6 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif Reo_sigmaC PF04582.7 KXX82529.1 - 0.019 14.1 0.5 0.03 13.5 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3538 PF12057.3 KXX82529.1 - 0.022 14.3 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) Fib_alpha PF08702.5 KXX82529.1 - 1.7 8.7 4.8 3.7 7.6 1.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 KXX82529.1 - 4.3 7.7 9.8 0.35 11.2 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF605 PF04652.11 KXX82530.1 - 0.9 8.8 16.5 1.1 8.6 11.4 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KXX82530.1 - 6.7 6.5 8.0 7.1 6.4 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.10 KXX82531.1 - 2.9e-12 46.1 9.5 6e-12 45.1 6.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KXX82531.1 - 7.3e-06 25.8 9.1 1.6e-05 24.7 6.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 KXX82531.1 - 0.037 13.9 0.5 0.081 12.9 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family XhlA PF10779.4 KXX82531.1 - 0.042 13.7 3.3 0.089 12.7 2.3 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Lzipper-MIP1 PF14389.1 KXX82531.1 - 0.15 12.1 3.3 0.29 11.2 2.3 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CENP-N PF05238.8 KXX82532.1 - 1.6e-121 406.1 0.0 1.9e-121 405.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TatD_DNase PF01026.16 KXX82533.1 - 9.1e-47 159.3 0.0 3.2e-46 157.6 0.0 1.8 1 1 0 1 1 1 1 TatD related DNase Ribosomal_60s PF00428.14 KXX82533.1 - 1.1 9.7 5.9 4.3 7.8 4.1 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribonuc_red_lgC PF02867.10 KXX82534.1 - 2.4e-222 739.2 0.0 3.2e-222 738.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KXX82534.1 - 9.3e-24 83.0 0.0 2.2e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KXX82534.1 - 1.3e-17 63.9 0.2 6.1e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain MMR_HSR1_C PF08438.5 KXX82534.1 - 0.029 14.6 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 GTPase of unknown function C-terminal AAA PF00004.24 KXX82535.1 - 2e-49 167.1 0.0 3.9e-42 143.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KXX82535.1 - 9.5e-07 28.4 0.0 6.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KXX82535.1 - 1.1e-06 28.8 0.9 0.00011 22.2 0.1 3.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 KXX82535.1 - 2.6e-05 24.2 0.0 6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KXX82535.1 - 3.4e-05 24.0 0.0 0.0024 18.0 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 KXX82535.1 - 0.0001 22.0 0.1 0.009 15.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX82535.1 - 0.00013 21.6 0.2 0.032 13.9 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KXX82535.1 - 0.0026 17.6 5.8 0.012 15.4 0.0 3.8 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.7 KXX82535.1 - 0.0029 16.6 0.0 0.033 13.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KXX82535.1 - 0.0054 16.7 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 KXX82535.1 - 0.0068 15.1 0.0 0.015 14.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Bromodomain PF00439.20 KXX82535.1 - 0.0069 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.17 KXX82535.1 - 0.0077 16.3 0.0 0.029 14.5 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KXX82535.1 - 0.0088 15.9 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX82535.1 - 0.0096 16.7 2.3 0.028 15.2 0.0 3.1 4 0 0 4 4 1 1 AAA domain Mg_chelatase PF01078.16 KXX82535.1 - 0.017 14.3 0.2 0.13 11.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KXX82535.1 - 0.034 12.9 0.0 0.19 10.5 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KXX82535.1 - 0.037 13.6 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX82535.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KXX82535.1 - 0.042 13.5 0.2 0.23 11.1 0.1 2.4 2 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KXX82535.1 - 0.056 13.7 0.0 0.056 13.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 KXX82535.1 - 0.066 13.1 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin Sigma54_activat PF00158.21 KXX82535.1 - 0.089 12.2 0.0 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain APH PF01636.18 KXX82536.1 - 0.04 13.6 3.5 0.14 11.9 2.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KXX82536.1 - 0.076 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 KXX82537.1 - 1.5e-16 60.7 0.0 3e-16 59.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82537.1 - 5.8e-07 29.3 0.0 8.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX82537.1 - 0.00099 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KXX82537.1 - 0.029 14.3 1.8 0.19 11.6 0.3 2.4 2 1 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KXX82537.1 - 0.099 12.4 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNA_pol_I_A49 PF06870.7 KXX82538.1 - 2.2e-79 266.8 1.6 2.5e-79 266.6 1.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Arfaptin PF06456.8 KXX82538.1 - 0.088 12.1 1.7 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Arfaptin-like domain CTK3 PF12243.3 KXX82539.1 - 1.7e-58 196.1 1.5 2.4e-58 195.7 1.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KXX82539.1 - 7.2e-22 77.2 8.8 2.1e-21 75.7 6.1 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Fib_alpha PF08702.5 KXX82539.1 - 0.59 10.2 3.7 8.2 6.5 0.1 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family P5CR_dimer PF14748.1 KXX82540.1 - 3.9e-34 116.8 0.6 3.9e-34 116.8 0.4 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KXX82540.1 - 1.7e-14 53.9 2.5 3.9e-12 46.4 0.0 2.6 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KXX82540.1 - 0.025 14.2 2.2 0.073 12.8 1.6 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.12 KXX82540.1 - 0.069 12.0 0.0 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 Prephenate dehydrogenase ApbA PF02558.11 KXX82540.1 - 0.16 11.4 1.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AAA_5 PF07728.9 KXX82541.1 - 2.7e-123 406.2 0.0 1.5e-21 76.5 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX82541.1 - 2.5e-31 109.0 11.7 1.9e-05 24.7 0.2 8.1 6 0 0 6 6 6 5 AAA ATPase domain AAA_3 PF07726.6 KXX82541.1 - 6.8e-29 100.1 0.0 3.2e-10 39.7 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KXX82541.1 - 7.4e-28 97.3 0.0 7.1e-05 23.0 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX82541.1 - 1.7e-26 93.3 0.6 0.0032 18.2 0.0 8.3 7 1 0 7 7 6 6 AAA domain AAA_22 PF13401.1 KXX82541.1 - 2.3e-25 89.2 2.8 0.009 16.1 0.0 9.5 8 1 0 8 8 6 6 AAA domain AAA_33 PF13671.1 KXX82541.1 - 2.3e-22 79.4 0.0 0.0039 17.0 0.0 7.8 7 1 0 7 7 6 4 AAA domain AAA_14 PF13173.1 KXX82541.1 - 9.9e-22 77.2 0.0 0.00022 21.1 0.0 7.9 8 0 0 8 8 7 4 AAA domain Sigma54_activat PF00158.21 KXX82541.1 - 1.1e-20 73.7 0.0 0.003 17.0 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.1 KXX82541.1 - 3.1e-20 72.7 0.6 0.0078 16.5 0.0 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 KXX82541.1 - 5.7e-19 68.5 1.1 7e-05 22.9 0.0 7.4 6 1 0 6 6 6 2 Sigma-54 interaction domain ABC_tran PF00005.22 KXX82541.1 - 4.8e-16 59.3 11.3 0.0066 16.7 0.0 8.5 8 0 0 8 8 7 4 ABC transporter T2SE PF00437.15 KXX82541.1 - 2.9e-15 55.9 5.6 0.014 14.3 0.0 7.1 8 0 0 8 8 7 3 Type II/IV secretion system protein NACHT PF05729.7 KXX82541.1 - 1.1e-14 54.4 4.5 0.16 11.6 0.0 6.3 6 0 0 6 6 5 4 NACHT domain AAA_19 PF13245.1 KXX82541.1 - 3.8e-14 52.2 6.4 0.014 15.1 0.3 6.6 6 0 0 6 6 6 3 Part of AAA domain RNA_helicase PF00910.17 KXX82541.1 - 6.9e-14 51.9 0.4 1.1 9.4 0.0 6.7 6 0 0 6 6 6 4 RNA helicase DUF258 PF03193.11 KXX82541.1 - 7.5e-14 51.2 1.6 0.025 13.7 0.0 6.4 6 0 0 6 6 6 3 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KXX82541.1 - 1.4e-13 50.4 0.1 0.11 11.6 0.0 6.8 6 0 0 6 6 6 2 Zeta toxin Arch_ATPase PF01637.13 KXX82541.1 - 2.8e-13 50.1 0.1 0.017 14.8 0.0 6.9 7 0 0 7 7 6 3 Archaeal ATPase UPF0079 PF02367.12 KXX82541.1 - 7.7e-13 48.1 3.6 0.079 12.5 0.0 5.6 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KXX82541.1 - 1.5e-12 46.8 0.1 0.031 13.7 0.0 6.4 6 0 0 6 6 6 2 P-loop containing region of AAA domain MobB PF03205.9 KXX82541.1 - 2.4e-12 46.7 3.0 1.4 8.6 0.0 6.6 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KXX82541.1 - 1.2e-11 44.4 0.2 1.4 8.2 0.0 6.1 5 0 0 5 5 5 3 AAA domain IstB_IS21 PF01695.12 KXX82541.1 - 2.5e-11 43.2 0.1 0.15 11.4 0.0 6.3 6 0 0 6 6 6 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KXX82541.1 - 3.5e-11 42.6 1.0 1.1 8.3 0.0 7.8 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KXX82541.1 - 4.6e-11 42.2 0.9 0.42 9.6 0.0 6.4 6 0 0 6 6 6 3 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KXX82541.1 - 7.2e-11 42.3 3.3 1 9.2 0.0 6.9 6 0 0 6 6 6 2 AAA domain SRP54 PF00448.17 KXX82541.1 - 2.6e-10 40.0 1.8 0.8 9.1 0.0 6.6 7 0 0 7 7 7 3 SRP54-type protein, GTPase domain Miro PF08477.8 KXX82541.1 - 8.8e-10 39.1 3.0 9.3 6.7 0.0 6.8 6 0 0 6 6 6 0 Miro-like protein DUF815 PF05673.8 KXX82541.1 - 1.2e-07 30.9 3.5 0.93 8.3 0.0 5.6 6 0 0 6 6 6 2 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KXX82541.1 - 1.7e-07 30.7 4.6 0.03 13.8 0.0 5.5 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KXX82541.1 - 2.8e-07 30.4 4.6 0.69 9.5 0.0 5.7 5 0 0 5 5 5 2 NTPase CbiA PF01656.18 KXX82541.1 - 1.2e-05 24.7 1.9 0.93 8.8 0.0 4.9 5 0 0 5 5 5 2 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.17 KXX82541.1 - 1.4e-05 24.1 3.2 8.7 5.1 0.0 6.3 6 0 0 6 6 6 0 NB-ARC domain Viral_helicase1 PF01443.13 KXX82541.1 - 1.6e-05 24.5 0.1 3.9 6.9 0.0 4.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 KXX82541.1 - 1.7e-05 24.7 1.4 21 5.0 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase Bac_DnaA PF00308.13 KXX82541.1 - 2.3e-05 24.1 0.9 4.9 6.7 0.0 5.2 5 0 0 5 5 5 0 Bacterial dnaA protein cobW PF02492.14 KXX82541.1 - 4.8e-05 22.8 6.6 3.3 7.1 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 KXX82541.1 - 6.1e-05 21.8 1.0 0.51 8.9 0.0 4.9 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 KXX82541.1 - 8.3e-05 21.4 0.4 3.5 6.2 0.0 5.2 6 0 0 6 6 6 0 TIP49 C-terminus ATP_bind_1 PF03029.12 KXX82541.1 - 9.9e-05 21.9 3.3 3 7.3 0.0 5.6 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 KXX82541.1 - 0.00011 21.4 1.7 11 5.0 0.0 5.0 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 DAP3 PF10236.4 KXX82541.1 - 0.00013 21.0 0.7 0.061 12.2 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 PhoH PF02562.11 KXX82541.1 - 0.00025 20.3 0.1 9 5.4 0.0 5.1 5 0 0 5 5 5 0 PhoH-like protein KaiC PF06745.8 KXX82541.1 - 0.004 16.2 0.0 5 6.1 0.0 4.1 3 0 0 3 3 3 0 KaiC APS_kinase PF01583.15 KXX82541.1 - 0.006 16.2 0.3 0.7 9.5 0.0 4.1 5 0 0 5 5 5 1 Adenylylsulphate kinase ATP-synt_ab PF00006.20 KXX82541.1 - 0.0083 15.6 0.0 20 4.5 0.0 4.8 5 1 0 6 6 5 0 ATP synthase alpha/beta family, nucleotide-binding domain Phe_ZIP PF08916.6 KXX82541.1 - 0.027 14.7 0.4 13 6.1 0.0 3.3 2 0 0 2 2 2 0 Phenylalanine zipper AAA_6 PF12774.2 KXX82541.1 - 0.22 11.0 0.0 78 2.6 0.0 4.2 6 0 0 6 6 3 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_21 PF13304.1 KXX82541.1 - 0.27 11.1 0.2 84 2.9 0.0 4.1 5 0 0 5 5 3 0 AAA domain FeoB_N PF02421.13 KXX82541.1 - 0.41 9.8 0.4 15 4.8 0.0 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B Ras PF00071.17 KXX82541.1 - 0.61 9.4 2.7 1.1e+02 2.1 0.0 4.5 5 0 0 5 5 5 0 Ras family Hpr_kinase_C PF07475.7 KXX82541.1 - 3.2 7.0 4.5 3.9 6.7 0.1 3.2 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain Ribosomal_L12 PF00542.14 KXX82542.1 - 2.9e-19 68.8 6.3 4e-18 65.1 2.5 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 KXX82542.1 - 0.042 13.9 0.3 2.4 8.3 0.0 2.4 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Hat1_N PF10394.4 KXX82543.1 - 3.8e-41 140.8 0.0 9e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Elong-fact-P_C PF09285.6 KXX82543.1 - 0.082 12.2 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 Elongation factor P, C-terminal Zip PF02535.17 KXX82544.1 - 2.6e-39 135.1 8.5 4.3e-38 131.0 5.9 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3995 PF13160.1 KXX82544.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.2 3 1 2 5 5 5 0 Protein of unknown function (DUF3995) Vma12 PF11712.3 KXX82544.1 - 0.89 9.2 2.9 2.2 8.0 2.0 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Het-C PF07217.6 KXX82545.1 - 2.5e-292 970.5 0.0 2.9e-292 970.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.23 KXX82546.1 - 2.7e-20 71.9 0.1 1.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KXX82546.1 - 1.4e-07 31.9 22.6 2e-07 31.3 14.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.13 KXX82547.1 - 8.5e-11 41.2 3.1 3.1e-09 36.0 0.0 3.7 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82547.1 - 5.9e-07 29.2 11.5 1e-06 28.5 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.26 KXX82548.1 - 0.051 13.5 0.1 3.4 7.6 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain Dynactin PF12455.3 KXX82549.1 - 4.2e-95 317.7 7.0 4.2e-95 317.7 4.8 3.1 3 2 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KXX82549.1 - 9.3e-24 82.9 0.6 1.7e-23 82.0 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 KXX82549.1 - 3.7 6.6 25.2 0.19 10.8 1.3 4.6 2 1 2 5 5 5 0 Reovirus sigma C capsid protein SRP19 PF01922.12 KXX82550.1 - 2.9e-29 101.4 0.0 5.7e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein DUF2360 PF10152.4 KXX82550.1 - 0.47 10.7 3.8 0.69 10.1 2.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CDP-OH_P_transf PF01066.16 KXX82551.1 - 7.9e-18 64.6 3.7 7.9e-18 64.6 2.6 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 KXX82552.1 - 8.9e-96 319.6 0.1 1.3e-95 319.0 0.1 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Dak2 PF02734.12 KXX82552.1 - 0.061 12.9 3.9 0.11 12.1 2.7 1.5 1 0 0 1 1 1 0 DAK2 domain TIP49 PF06068.8 KXX82554.1 - 7e-186 617.7 0.1 8.2e-186 617.4 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KXX82554.1 - 1.3e-11 44.7 0.1 5.8e-07 29.7 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX82554.1 - 4.2e-11 42.3 0.1 2.3e-07 30.1 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX82554.1 - 2.6e-05 23.8 0.1 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KXX82554.1 - 0.0003 20.9 0.1 0.83 9.8 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX82554.1 - 0.00034 20.6 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KXX82554.1 - 0.0014 18.0 0.1 0.006 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KXX82554.1 - 0.0022 17.9 0.3 0.0053 16.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX82554.1 - 0.0046 16.6 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KXX82554.1 - 0.0062 15.6 0.3 0.013 14.5 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KXX82554.1 - 0.0071 15.5 0.1 0.26 10.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KXX82554.1 - 0.0091 15.4 0.2 0.022 14.1 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 KXX82554.1 - 0.019 13.9 0.1 0.068 12.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 KXX82554.1 - 0.028 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 KXX82554.1 - 0.029 13.8 0.1 0.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KXX82554.1 - 0.044 14.1 0.1 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KXX82554.1 - 0.062 14.1 0.1 0.15 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 KXX82555.1 - 2.8e-23 81.9 2.5 4.5e-23 81.2 1.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX82555.1 - 6.4e-09 36.0 1.8 1.4e-08 34.9 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain zf-H2C2_2 PF13465.1 KXX82555.1 - 0.093 13.0 0.4 0.35 11.2 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger double domain WES_acyltransf PF03007.11 KXX82556.1 - 0.5 9.8 2.4 6.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain SNF2_N PF00176.18 KXX82557.1 - 5.4e-84 281.5 1.2 5.4e-84 281.5 0.8 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KXX82557.1 - 2.3e-20 72.2 0.0 6.7e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 KXX82557.1 - 2.2e-17 62.9 0.6 2.2e-17 62.9 0.4 4.5 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KXX82557.1 - 2.6e-16 59.2 0.0 2.6e-16 59.2 0.0 4.6 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.8 KXX82557.1 - 1.3e-15 56.9 9.9 1.3e-15 56.9 6.9 3.6 5 0 0 5 5 5 1 HSA QLQ PF08880.6 KXX82557.1 - 2.8e-10 39.4 0.9 2.8e-10 39.4 0.6 2.2 2 0 0 2 2 2 1 QLQ LRR_4 PF12799.2 KXX82559.1 - 9.7e-35 117.6 21.5 1.3e-05 24.7 0.6 8.5 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX82559.1 - 2.8e-19 68.6 32.4 3.7e-06 26.5 6.9 7.2 4 2 4 8 8 8 5 Leucine rich repeat LRR_9 PF14580.1 KXX82559.1 - 4e-08 33.0 9.0 0.0036 16.8 0.9 4.1 2 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 KXX82559.1 - 7.7e-07 28.2 37.9 0.82 9.9 0.0 12.1 11 1 1 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.1 KXX82559.1 - 0.028 14.4 36.8 2.3 8.5 0.2 9.3 9 2 1 10 10 10 0 Leucine Rich repeat LRR_7 PF13504.1 KXX82559.1 - 0.038 14.1 40.7 1.4 9.4 0.1 10.9 11 0 0 11 11 11 0 Leucine rich repeat VWA PF00092.23 KXX82560.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KXX82560.1 - 4.2e-08 33.4 0.0 6.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KXX82560.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 KXX82560.1 - 0.036 13.7 0.0 0.088 12.4 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Cytidylate_kin PF02224.13 KXX82560.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Aminotran_1_2 PF00155.16 KXX82561.1 - 7.5e-39 133.6 0.0 9e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KXX82561.1 - 0.037 13.1 0.0 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase Glycos_transf_1 PF00534.15 KXX82562.1 - 7.2e-33 113.4 0.0 7.5e-31 106.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KXX82562.1 - 4.4e-08 33.4 0.4 4.4e-08 33.4 0.3 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KXX82562.1 - 1.2e-07 31.6 0.4 1e-06 28.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KXX82562.1 - 1.9e-07 31.2 0.0 4.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KXX82562.1 - 1.8e-06 28.1 0.4 2.4e-05 24.5 0.1 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Pkinase PF00069.20 KXX82563.1 - 2.7e-52 177.4 0.1 1.5e-36 125.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82563.1 - 5.1e-21 74.8 0.1 1.3e-19 70.2 0.1 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX82563.1 - 7.9e-06 25.0 0.0 2.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KXX82563.1 - 0.00054 19.7 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family CFEM PF05730.6 KXX82564.1 - 9.1e-12 44.6 3.7 1.5e-11 43.9 2.6 1.3 1 0 0 1 1 1 1 CFEM domain Endonuclease_NS PF01223.18 KXX82565.1 - 1.1e-60 204.7 0.0 1.7e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Patatin PF01734.17 KXX82565.1 - 0.029 14.3 1.9 0.079 12.8 1.3 1.7 1 1 0 1 1 1 0 Patatin-like phospholipase WD40 PF00400.27 KXX82567.1 - 1e-20 72.7 11.9 2.1e-06 27.4 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIIF_alpha PF05793.7 KXX82567.1 - 0.0024 16.3 3.7 0.012 14.0 1.3 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vfa1 PF08432.5 KXX82567.1 - 0.021 14.8 1.0 0.035 14.1 0.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 F-protein PF00469.15 KXX82567.1 - 0.11 11.8 0.6 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Tom22 PF04281.8 KXX82567.1 - 0.26 10.8 3.0 0.51 9.8 2.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DSBA PF01323.15 KXX82568.1 - 7.2e-17 61.5 0.0 3.4e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain tify PF06200.9 KXX82568.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 tify domain BCNT PF07572.7 KXX82569.1 - 1.2e-25 89.2 0.6 2.8e-25 88.0 0.4 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Zn_clus PF00172.13 KXX82570.1 - 2.6e-06 27.2 11.1 4.8e-06 26.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_ligase_A_M PF01068.16 KXX82571.1 - 3.5e-57 193.0 1.0 7.2e-46 156.1 0.3 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KXX82571.1 - 5.9e-53 179.2 0.1 1.3e-52 178.2 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KXX82571.1 - 1e-27 96.3 0.3 3.9e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region E1_dh PF00676.15 KXX82572.1 - 5.2e-113 376.7 0.1 6.8e-113 376.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KXX82572.1 - 0.0016 17.4 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 KXX82573.1 - 1.5e-49 164.1 24.6 1.9e-10 40.2 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KXX82573.1 - 1.9e-12 46.6 0.9 3.6e-12 45.8 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KXX82573.1 - 2.4e-09 35.9 12.6 0.016 13.3 0.2 5.9 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 KXX82573.1 - 5.8e-06 25.8 2.3 1.1e-05 24.9 1.6 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KXX82573.1 - 0.0087 15.5 6.2 2.4 7.5 0.6 4.0 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 KXX82573.1 - 0.28 11.5 6.1 13 6.2 0.1 4.6 4 1 0 4 4 4 0 PQQ-like domain Helicase_C_3 PF13625.1 KXX82574.1 - 2.6e-26 91.8 0.0 2.5e-25 88.6 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX82574.1 - 7.5e-17 61.7 0.0 1.7e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KXX82574.1 - 5.7e-11 41.7 0.0 9e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX82574.1 - 2.2e-10 40.2 0.0 5.7e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CHY PF05495.7 KXX82575.1 - 3.9e-10 39.7 9.9 5.3e-10 39.3 6.8 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KXX82575.1 - 0.048 13.4 7.5 0.71 9.7 2.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 KXX82575.1 - 0.055 13.1 9.9 0.084 12.5 6.9 1.3 1 0 0 1 1 1 0 Cytochrome c7 RNHCP PF12647.2 KXX82575.1 - 0.15 11.9 4.9 0.11 12.3 1.0 2.1 2 0 0 2 2 2 0 RNHCP domain HypA PF01155.14 KXX82575.1 - 0.53 9.9 9.4 0.15 11.7 3.1 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_4 PF07975.7 KXX82575.1 - 0.97 9.4 12.5 8 6.5 4.9 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3797 PF12677.2 KXX82575.1 - 1.5 8.5 0.0 1.5 8.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.5 KXX82575.1 - 1.5 8.8 12.8 3 7.8 5.7 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Terminase_GpA PF05876.7 KXX82575.1 - 1.7 6.9 4.9 1.9 6.7 3.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-RING_3 PF14369.1 KXX82575.1 - 2.5 8.1 11.8 1 9.3 4.6 2.6 1 1 2 3 3 3 0 zinc-finger Cytochrom_c3_2 PF14537.1 KXX82575.1 - 6.2 7.2 12.5 25 5.2 8.7 1.8 1 1 0 1 1 1 0 Cytochrome c3 Evr1_Alr PF04777.8 KXX82575.1 - 6.3 6.7 10.2 91 3.0 7.0 2.6 1 1 1 2 2 2 0 Erv1 / Alr family Proteasome PF00227.21 KXX82576.1 - 3.6e-56 189.4 0.1 5.8e-56 188.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX82576.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 KXX82577.1 - 1.2e-61 208.2 0.0 1.6e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KXX82577.1 - 7.9e-37 125.8 0.5 1.4e-36 125.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.12 KXX82578.1 - 4e-78 260.9 25.0 4.8e-78 260.7 17.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 TrkH PF02386.11 KXX82579.1 - 9.1e-122 406.0 22.4 3.3e-119 397.5 9.4 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_S4e PF00900.15 KXX82580.1 - 7.6e-32 108.8 0.5 1.5e-31 107.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KXX82580.1 - 5.3e-19 67.7 3.5 1e-18 66.8 2.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KXX82580.1 - 7.8e-06 25.2 0.0 1.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KXX82580.1 - 0.00031 20.3 1.3 0.00031 20.3 0.9 3.2 4 0 0 4 4 4 1 KOW motif Glyco_hydro_18 PF00704.23 KXX82582.1 - 6.3e-16 58.7 0.0 6.3e-16 58.7 0.0 2.9 2 2 0 3 3 3 1 Glycosyl hydrolases family 18 LysM PF01476.15 KXX82582.1 - 4e-08 33.0 0.0 8.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 LysM domain Myb_DNA-binding PF00249.26 KXX82583.1 - 1.8e-13 50.3 0.4 3.1e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX82583.1 - 2e-11 43.7 0.2 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Mid2 PF04478.7 KXX82585.1 - 0.00048 19.5 2.2 0.0016 17.8 1.5 1.9 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 KXX82585.1 - 0.075 12.3 0.6 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF605 PF04652.11 KXX82585.1 - 4.9 6.4 23.3 7.4 5.8 16.1 1.3 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 KXX82585.1 - 6.9 6.7 12.0 1.1e+02 2.8 8.3 2.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.4 KXX82585.1 - 7.7 4.9 9.5 11 4.4 6.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 PAM2 PF07145.10 KXX82586.1 - 0.00065 19.0 12.1 0.061 12.8 0.4 5.0 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Exo_endo_phos PF03372.18 KXX82587.1 - 4.9e-17 62.6 0.0 7.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KXX82587.1 - 7.5e-17 61.0 0.0 2.3e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KXX82587.1 - 7.4e-06 25.7 0.4 1.9e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 GRF zinc finger DUF572 PF04502.8 KXX82587.1 - 1.8 7.6 7.1 2.7 7.1 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) HMG_box PF00505.14 KXX82589.1 - 6.2e-22 77.6 0.3 1.3e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX82589.1 - 8.8e-07 29.2 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Alpha_E1_glycop PF01589.11 KXX82589.1 - 0.1 10.9 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein ANTH PF07651.11 KXX82590.1 - 1.3e-80 270.0 1.2 2.8e-80 269.0 0.0 2.3 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KXX82590.1 - 7.7e-64 214.2 9.2 7.7e-64 214.2 6.3 5.5 5 2 3 8 8 8 1 I/LWEQ domain ENTH PF01417.15 KXX82590.1 - 0.0023 17.8 0.0 0.01 15.7 0.0 2.2 1 0 0 1 1 1 1 ENTH domain Autophagy_N PF03986.8 KXX82591.1 - 7.7e-45 152.2 0.5 1.2e-44 151.5 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KXX82591.1 - 1.3e-22 79.7 1.3 6.5e-22 77.4 0.3 2.3 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KXX82591.1 - 1.7e-14 52.5 0.5 3.3e-14 51.6 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-CCCH PF00642.19 KXX82592.1 - 3e-08 33.1 2.1 5.9e-08 32.2 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KXX82592.1 - 1e-07 31.4 2.9 1.6e-07 30.8 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX82592.1 - 4.3e-07 29.8 8.0 7.5e-07 29.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX82592.1 - 3.1e-06 26.7 5.9 5.6e-06 25.9 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX82592.1 - 1.3e-05 24.9 4.7 2e-05 24.3 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX82592.1 - 1.8e-05 24.3 6.0 3.1e-05 23.6 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KXX82592.1 - 0.006 16.2 0.8 0.015 15.0 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KXX82592.1 - 0.059 13.2 7.0 0.13 12.1 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Harakiri PF15196.1 KXX82592.1 - 0.48 10.6 3.4 0.42 10.8 1.0 1.9 2 0 0 2 2 2 0 Activator of apoptosis harakiri TRP PF06011.7 KXX82593.1 - 2.4e-91 306.5 18.1 3.3e-91 306.0 12.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KXX82593.1 - 3.2e-25 88.8 0.0 5.7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ML-like domain MIP-T3 PF10243.4 KXX82594.1 - 0.5 8.7 22.1 0.76 8.1 15.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 COX6A PF02046.10 KXX82595.1 - 1.2e-44 150.8 1.9 1.3e-44 150.8 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Sirohm_synth_M PF14824.1 KXX82595.1 - 0.13 11.2 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Apc5 PF12862.2 KXX82596.1 - 8.9e-31 105.5 1.6 2.9e-30 103.9 1.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_21 PF09976.4 KXX82596.1 - 0.00053 19.9 2.5 0.011 15.6 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KXX82596.1 - 0.00093 19.0 13.4 8.5 6.3 0.2 5.1 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX82596.1 - 0.0019 18.6 17.0 1.1 10.0 0.9 6.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX82596.1 - 0.019 15.6 16.8 2.9 8.6 0.0 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KXX82596.1 - 0.039 13.7 5.2 6.6 6.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KXX82596.1 - 0.046 14.0 8.2 10 6.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KXX82596.1 - 0.11 12.4 9.4 30 4.8 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ZU5 PF00791.15 KXX82596.1 - 0.2 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 ZU5 domain TPR_1 PF00515.23 KXX82596.1 - 0.23 11.1 6.2 17 5.1 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KXX82596.1 - 8.4 7.1 17.1 39 5.0 1.4 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat PA PF02225.17 KXX82597.1 - 1.2e-11 44.1 0.0 2.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_2 PF13639.1 KXX82597.1 - 9e-07 28.6 2.6 1.4e-06 27.9 1.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KXX82597.1 - 0.00064 19.6 1.7 0.001 19.0 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX82597.1 - 0.00079 19.0 0.7 0.0012 18.4 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KXX82597.1 - 0.009 15.6 1.9 0.014 15.0 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KXX82597.1 - 0.016 14.9 0.9 0.025 14.3 0.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 KXX82597.1 - 0.053 13.6 1.1 0.1 12.7 0.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger tRNA-synt_1 PF00133.17 KXX82598.1 - 4.7e-224 744.8 0.0 3.8e-223 741.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KXX82598.1 - 2.2e-35 121.6 0.0 6.3e-35 120.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KXX82598.1 - 7.4e-17 61.0 0.5 0.00024 19.8 0.0 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KXX82598.1 - 1.3e-11 44.1 0.1 6.5e-08 32.0 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KXX82598.1 - 0.00085 18.5 0.0 0.016 14.3 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_L37e PF01907.14 KXX82599.1 - 5.6e-27 93.2 11.5 8.3e-27 92.7 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KXX82599.1 - 0.0014 18.4 1.0 0.0019 17.9 0.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KXX82599.1 - 0.0079 15.3 1.1 0.015 14.4 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 KXX82599.1 - 0.059 13.0 0.5 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S14 PF00253.16 KXX82599.1 - 0.27 10.6 8.7 0.3 10.5 0.7 2.5 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e zf-C3HC4 PF00097.20 KXX82599.1 - 0.35 10.5 3.7 0.58 9.8 2.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 KXX82599.1 - 0.62 9.6 2.5 1.4 8.5 1.4 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KXX82599.1 - 4.9 6.7 7.6 26 4.4 5.3 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF2348 PF09807.4 KXX82600.1 - 0.001 18.2 0.2 0.0039 16.3 0.0 1.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2348) MFS_1 PF07690.11 KXX82601.1 - 5.2e-38 130.6 38.1 3.7e-37 127.8 21.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82601.1 - 2.2e-11 43.0 12.6 2.2e-11 43.0 8.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Thioredoxin PF00085.15 KXX82602.1 - 3.1e-06 26.7 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KXX82602.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 KXX82602.1 - 0.056 13.6 0.0 1.5 9.0 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Spc7 PF08317.6 KXX82603.1 - 0.00063 18.5 2.5 0.35 9.4 0.0 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein IncA PF04156.9 KXX82603.1 - 0.007 15.9 5.5 0.36 10.3 2.0 2.4 1 1 1 2 2 2 2 IncA protein BLOC1_2 PF10046.4 KXX82603.1 - 0.01 15.9 3.1 0.11 12.6 0.0 2.7 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lge1 PF11488.3 KXX82603.1 - 0.02 15.1 0.9 4.1 7.6 0.0 3.0 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 HAUS-augmin3 PF14932.1 KXX82603.1 - 0.027 13.6 0.1 0.076 12.1 0.1 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.4 KXX82603.1 - 0.043 13.6 9.4 1.9 8.3 3.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 KXX82603.1 - 0.088 12.4 0.3 8.8 6.0 0.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit PuR_N PF09182.5 KXX82603.1 - 0.099 12.2 0.0 27 4.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal SlyX PF04102.7 KXX82603.1 - 0.13 12.6 8.5 0.4 11.0 0.5 3.7 4 0 0 4 4 4 0 SlyX Atg14 PF10186.4 KXX82603.1 - 0.19 10.6 9.1 1.6 7.5 2.6 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KXX82603.1 - 0.25 11.1 12.0 1.1 8.9 1.7 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 KXX82603.1 - 0.53 9.8 13.1 19 4.8 0.1 3.7 2 1 0 3 3 3 0 Septum formation initiator AAA_13 PF13166.1 KXX82603.1 - 1.4 7.2 7.4 0.2 10.1 0.6 2.3 1 1 1 2 2 2 0 AAA domain DUF972 PF06156.8 KXX82603.1 - 4 7.8 8.5 2.7 8.3 1.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 KXX82603.1 - 4.6 6.5 11.3 5 6.4 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FemAB PF02388.11 KXX82603.1 - 5.8 5.4 7.5 0.29 9.7 0.0 2.3 2 1 1 3 3 3 0 FemAB family TPR_MLP1_2 PF07926.7 KXX82603.1 - 6 6.6 13.4 1.3 8.7 0.1 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C2H2_4 PF13894.1 KXX82604.1 - 0.078 13.3 0.3 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger bZIP_1 PF00170.16 KXX82605.1 - 2.4e-07 30.5 16.9 3.9e-07 29.9 11.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 KXX82605.1 - 0.00026 20.6 4.5 0.00035 20.1 3.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF972 PF06156.8 KXX82605.1 - 0.019 15.3 1.5 0.039 14.2 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 KXX82605.1 - 0.029 14.1 19.7 0.1 12.4 12.4 2.2 1 1 1 2 2 2 0 Basic region leucine zipper ADIP PF11559.3 KXX82605.1 - 0.11 12.4 12.2 6.8 6.5 9.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KXX82605.1 - 0.11 10.3 1.0 0.12 10.1 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.12 KXX82605.1 - 0.13 12.5 17.3 0.46 10.8 12.2 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor PA26 PF04636.8 KXX82605.1 - 0.14 10.8 0.7 0.16 10.6 0.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Glutaredoxin2_C PF04399.8 KXX82605.1 - 0.16 11.5 2.5 0.29 10.7 1.7 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF342 PF03961.8 KXX82605.1 - 0.23 9.8 1.0 0.32 9.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LMSTEN PF07988.7 KXX82605.1 - 0.64 9.3 3.3 7.2 5.9 0.1 3.1 3 0 0 3 3 3 0 LMSTEN motif DAZAP2 PF11029.3 KXX82605.1 - 1.9 8.9 15.0 0.79 10.1 8.5 1.7 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) IncA PF04156.9 KXX82605.1 - 3.1 7.3 9.2 4.6 6.7 6.3 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KXX82605.1 - 3.5 6.5 8.9 4.7 6.1 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 KXX82605.1 - 4.9 6.8 5.3 8 6.1 3.7 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Septin PF00735.13 KXX82607.1 - 5.9e-32 110.8 0.0 1.6e-11 43.8 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KXX82607.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KXX82607.1 - 0.015 16.1 0.0 0.045 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 KXX82607.1 - 0.017 13.8 0.0 0.038 12.6 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.1 KXX82607.1 - 0.019 15.3 0.1 0.04 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KXX82607.1 - 0.025 14.3 0.5 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 KXX82607.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 KXX82607.1 - 0.063 13.5 0.2 0.2 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KXX82607.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ecl1 PF12855.2 KXX82608.1 - 0.00017 20.7 3.3 0.09 12.0 0.1 2.6 2 0 0 2 2 2 2 Life-span regulatory factor zf-MYND PF01753.13 KXX82608.1 - 0.03 14.1 16.3 0.09 12.6 0.8 3.1 3 0 0 3 3 3 0 MYND finger Amidohydro_2 PF04909.9 KXX82608.1 - 0.097 12.2 0.6 0.15 11.6 0.4 1.5 1 1 0 1 1 1 0 Amidohydrolase SUR7 PF06687.7 KXX82609.1 - 5.2e-27 94.8 15.2 6.4e-27 94.4 10.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 KXX82609.1 - 0.01 16.0 3.8 0.01 16.0 2.6 2.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding CobD_Cbib PF03186.8 KXX82609.1 - 0.51 9.3 2.7 0.8 8.7 1.9 1.2 1 0 0 1 1 1 0 CobD/Cbib protein YesK PF14150.1 KXX82609.1 - 1.2 9.3 13.2 3 7.9 2.5 2.4 2 0 0 2 2 2 0 YesK-like protein ABC1 PF03109.11 KXX82610.1 - 1.3e-21 76.7 0.0 4.4e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 KXX82610.1 - 0.0083 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family 2OG-FeII_Oxy_3 PF13640.1 KXX82611.1 - 3.6e-12 46.6 0.0 5.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KXX82611.1 - 6.1e-07 28.9 0.2 1.3e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KXX82611.1 - 0.00031 20.9 0.0 0.00054 20.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD-oxidase_C PF02913.14 KXX82612.1 - 2.7e-60 203.7 0.1 1.3e-59 201.5 0.0 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KXX82612.1 - 9.7e-35 119.0 0.0 1.8e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KXX82612.1 - 0.12 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) SF3b10 PF07189.6 KXX82613.1 - 8.4e-43 144.0 0.0 9.8e-43 143.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KXX82614.1 - 2.9e-44 150.7 0.0 3.6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 MAGE family SUI1 PF01253.17 KXX82615.1 - 2.7e-29 100.8 2.5 3.5e-29 100.4 1.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KXX82615.1 - 0.035 14.1 0.1 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) DUF2575 PF10837.3 KXX82615.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) EOS1 PF12326.3 KXX82616.1 - 2.8e-28 98.4 11.0 2e-23 82.6 3.2 2.2 1 1 1 2 2 2 2 N-glycosylation protein Dpy19 PF10034.4 KXX82616.1 - 0.15 10.1 3.0 0.2 9.7 2.1 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Dioxygenase_C PF00775.16 KXX82617.1 - 6.7e-53 178.6 0.0 1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KXX82617.1 - 5.4e-17 61.5 0.0 1.4e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KXX82617.1 - 1e-05 25.5 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.6 KXX82617.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) AdoMet_MTase PF07757.8 KXX82618.1 - 9.4e-37 125.5 0.0 1.6e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KXX82618.1 - 0.0026 17.4 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82618.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KXX82618.1 - 0.04 13.6 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.17 KXX82619.1 - 4.3e-27 93.5 2.2 2.7e-14 52.5 0.0 3.6 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX82619.1 - 3.6e-15 55.6 0.3 8.1e-07 28.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX82619.1 - 3.3e-13 49.2 0.2 4e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim44 PF04280.10 KXX82620.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain Imm14 PF15428.1 KXX82620.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 14 SSF PF00474.12 KXX82621.1 - 1.6e-10 40.2 32.4 6.3e-10 38.2 22.4 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family Adaptin_N PF01602.15 KXX82623.1 - 2e-115 386.1 0.6 2.5e-115 385.7 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KXX82623.1 - 7e-57 191.4 4.9 1.3e-56 190.5 3.4 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KXX82623.1 - 2.1e-15 56.7 1.0 2.6e-05 24.4 0.1 6.2 2 1 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 KXX82623.1 - 0.00056 20.1 0.5 0.98 10.0 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat MRP-S35 PF10246.4 KXX82623.1 - 0.0045 16.8 0.0 0.045 13.6 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein MRP-S35 HEAT PF02985.17 KXX82623.1 - 0.08 13.0 6.4 2 8.7 0.2 4.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KXX82623.1 - 0.22 12.0 3.6 0.8 10.2 0.7 3.2 2 0 0 2 2 2 0 HEAT-like repeat CDP-OH_P_transf PF01066.16 KXX82624.1 - 2.7e-16 59.6 1.8 2.7e-16 59.6 1.2 2.7 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Lipase_3 PF01764.20 KXX82625.1 - 1.2e-15 57.3 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KXX82625.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82625.1 - 0.0083 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KXX82625.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein REV PF00424.13 KXX82626.1 - 3.3 7.6 5.8 4.2 7.3 1.0 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) UPF0016 PF01169.14 KXX82627.1 - 6.3e-44 148.0 22.9 1.1e-22 79.9 5.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-bind_6 PF13921.1 KXX82628.1 - 0.0082 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ATP-sulfurylase PF01747.12 KXX82629.1 - 3e-88 294.7 0.1 4.1e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KXX82629.1 - 3.4e-57 192.4 0.0 5.4e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KXX82629.1 - 9.3e-53 177.8 0.0 1.5e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KXX82629.1 - 0.0093 15.8 0.3 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF3857 PF12969.2 KXX82629.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) KTI12 PF08433.5 KXX82629.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 EI24 PF07264.6 KXX82630.1 - 4.6e-05 22.9 5.3 0.00019 20.9 3.7 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.19 KXX82630.1 - 1.2 8.4 4.9 0.51 9.7 0.8 1.9 2 0 0 2 2 2 0 Fatty acid desaturase CIA30 PF08547.7 KXX82631.1 - 2.1e-44 151.1 0.0 2.9e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) JmjC PF02373.17 KXX82632.1 - 2.9e-18 66.1 0.0 5.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.23 KXX82632.1 - 2.1e-07 31.4 0.0 8.2e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 SET domain Mcp5_PH PF12814.2 KXX82633.1 - 2.4e-43 146.9 0.1 5.4e-43 145.8 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_12 PF13424.1 KXX82634.1 - 2.9e-17 62.3 5.1 7.3e-06 25.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KXX82634.1 - 2.1e-08 33.6 5.5 0.0022 17.6 0.0 4.7 3 1 3 6 6 6 4 TPR repeat TPR_16 PF13432.1 KXX82634.1 - 1.8e-07 31.6 14.5 0.067 13.8 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KXX82634.1 - 2.7e-06 27.1 13.4 0.0018 18.1 0.6 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX82634.1 - 1.6e-05 24.4 12.2 0.55 10.2 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KXX82634.1 - 1.7e-05 24.2 1.1 0.46 10.3 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KXX82634.1 - 0.00032 20.9 9.5 0.0068 16.7 0.6 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KXX82634.1 - 0.001 19.5 25.8 5.9 7.8 0.1 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KXX82634.1 - 0.0016 17.9 4.5 0.2 11.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KXX82634.1 - 0.07 12.9 6.8 4.8 7.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 KXX82634.1 - 0.14 11.6 0.1 0.59 9.5 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 KXX82634.1 - 2.3 8.8 14.9 30 5.3 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 KXX82636.1 - 2.4e-47 159.2 13.2 2.4e-16 59.8 0.0 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82636.1 - 1.8e-31 106.3 12.6 7.4e-07 28.6 0.6 10.5 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 KXX82636.1 - 1.3e-20 73.3 7.2 0.00048 20.5 0.0 6.8 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82636.1 - 6.5e-19 66.1 8.2 0.00038 20.4 0.0 9.1 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 KXX82636.1 - 8e-18 64.0 6.1 7.4e-05 22.8 0.0 6.9 2 2 4 6 6 6 4 Ankyrin repeats (many copies) NACHT PF05729.7 KXX82636.1 - 3.3e-08 33.3 0.0 7.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KXX82636.1 - 1.1e-07 32.0 0.5 4.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KXX82636.1 - 0.02 15.0 0.0 0.081 13.1 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KXX82636.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KXX82636.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KXX82636.1 - 0.062 12.2 0.0 0.66 8.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 KXX82636.1 - 0.065 13.1 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KXX82636.1 - 0.095 12.8 0.0 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mucin PF01456.12 KXX82638.1 - 0.36 10.5 7.7 1.4 8.7 5.3 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein NB-ARC PF00931.17 KXX82641.1 - 1.6e-21 76.4 0.0 2.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KXX82641.1 - 1.3e-08 35.0 0.8 9.6e-05 22.4 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KXX82641.1 - 1.5e-05 25.1 0.0 5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Dabb PF07876.7 KXX82643.1 - 9.1e-23 80.5 0.0 1.3e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain PAPS_reduct PF01507.14 KXX82645.1 - 3.5e-20 72.5 0.0 1.8e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ETC_C1_NDUFA5 PF04716.9 KXX82646.1 - 0.17 11.4 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 ETC complex I subunit conserved region ADH_zinc_N_2 PF13602.1 KXX82647.1 - 2.7e-21 76.7 0.0 9.1e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KXX82647.1 - 7.1e-18 64.4 0.2 1.1e-17 63.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KXX82647.1 - 0.006 16.6 0.9 0.0094 15.9 0.6 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KXX82647.1 - 0.0076 15.7 0.1 0.0098 15.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KXX82647.1 - 0.021 14.7 1.1 0.039 13.8 0.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KXX82647.1 - 0.068 13.0 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NUDIX PF00293.23 KXX82648.1 - 3.7e-14 52.5 0.2 5.1e-14 52.0 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain LDB19 PF13002.2 KXX82649.1 - 2.6e-34 118.4 0.3 3.9e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KXX82649.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SQS_PSY PF00494.14 KXX82650.1 - 6.3e-59 199.4 0.0 2.2e-58 197.6 0.0 1.7 1 1 0 1 1 1 1 Squalene/phytoene synthase LIP PF03583.9 KXX82651.1 - 2.7e-58 197.4 0.2 3.6e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 KXX82651.1 - 0.0027 16.9 0.2 0.35 10.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3237 PF11578.3 KXX82652.1 - 9.9e-24 83.3 0.1 1.5e-23 82.7 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) SNF2_N PF00176.18 KXX82653.1 - 6.3e-71 238.6 0.0 9.7e-71 237.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KXX82653.1 - 1.5e-27 95.5 0.0 3.1e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KXX82653.1 - 9.4e-14 51.0 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KXX82653.1 - 1.7e-06 27.9 9.3 3.8e-06 26.8 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX82653.1 - 0.00039 20.0 9.4 0.00083 18.9 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KXX82653.1 - 0.0011 18.8 0.0 0.0036 17.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 KXX82653.1 - 0.0039 16.8 8.1 0.0076 15.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KXX82653.1 - 0.0047 16.7 10.4 0.011 15.5 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KXX82653.1 - 0.46 10.2 8.3 1.1 8.9 5.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain IU_nuc_hydro PF01156.14 KXX82655.1 - 2.1e-22 79.7 0.0 2.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HET PF06985.6 KXX82656.1 - 4.5e-23 81.9 0.0 6.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.13 KXX82657.1 - 1.9e-06 27.1 0.3 3.7e-05 22.9 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 PTCB-BRCT PF12738.2 KXX82659.1 - 3.8e-42 141.9 0.4 1.9e-21 75.6 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KXX82659.1 - 5.8e-36 122.4 2.1 8.3e-13 48.3 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain K_channel_TID PF07941.6 KXX82659.1 - 5.5 7.2 20.4 0.15 12.3 2.5 3.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Lin-8 PF03353.10 KXX82659.1 - 6.4 5.9 5.6 3.1 6.9 2.0 1.8 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA PF00004.24 KXX82662.1 - 3.5e-07 30.4 0.0 3.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KXX82662.1 - 3.9e-05 23.8 0.0 0.0005 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KXX82662.1 - 0.00066 18.4 0.0 0.0028 16.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KXX82662.1 - 0.0015 19.3 0.0 0.0038 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX82662.1 - 0.0019 18.1 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KXX82662.1 - 0.039 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KXX82662.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Asp PF00026.18 KXX82663.1 - 5e-57 193.5 0.0 6.1e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KXX82663.1 - 2.3e-13 50.4 0.5 2.4e-11 43.8 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KXX82663.1 - 0.0017 17.9 0.0 0.95 8.9 0.0 2.6 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KXX82663.1 - 0.065 13.7 0.5 23 5.5 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease UEV PF05743.8 KXX82663.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 UEV domain Sensor_TM1 PF13755.1 KXX82664.1 - 0.26 10.7 1.2 0.37 10.3 0.9 1.3 1 1 0 1 1 1 0 Sensor N-terminal transmembrane domain HET PF06985.6 KXX82666.1 - 3.2e-20 72.7 0.0 7.4e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.17 KXX82667.1 - 4.6e-42 144.1 8.0 5.9e-42 143.7 5.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AMP-binding PF00501.23 KXX82668.1 - 3.6e-65 220.0 0.0 4.8e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KXX82668.1 - 1.5e-15 56.8 0.0 4.7e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 KXX82668.1 - 0.00045 21.1 0.2 0.0012 19.7 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 KXX82669.1 - 3e-59 200.5 1.1 9.1e-59 198.9 0.8 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX82669.1 - 2.7e-49 168.2 0.9 4.4e-49 167.5 0.6 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KXX82669.1 - 1.2e-48 165.1 0.0 4.4e-48 163.3 0.0 2.1 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 KXX82669.1 - 1.8e-42 145.0 0.2 8.6e-42 142.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KXX82669.1 - 5e-37 127.6 0.0 1.4e-36 126.2 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KXX82669.1 - 7.5e-35 119.3 0.2 2.1e-34 117.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX82669.1 - 1.4e-17 64.0 0.0 3.6e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KXX82669.1 - 1e-14 54.2 0.0 4.2e-14 52.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KXX82669.1 - 8.6e-14 51.5 0.0 2.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KXX82669.1 - 3.1e-10 40.1 0.1 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KXX82669.1 - 5.8e-09 35.7 0.0 2.2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82669.1 - 2.7e-07 30.9 0.0 1.2e-06 28.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KXX82669.1 - 3e-07 30.1 0.0 7.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KXX82669.1 - 5.9e-07 30.4 0.0 2.5e-06 28.4 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KXX82669.1 - 1.3e-06 28.9 0.0 2.2e-05 24.9 0.0 3.2 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82669.1 - 0.00094 19.5 0.0 0.0095 16.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_16 PF10294.4 KXX82669.1 - 0.0028 17.1 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase YbbR PF07949.7 KXX82669.1 - 0.0093 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 YbbR-like protein DREV PF05219.7 KXX82669.1 - 0.025 13.4 0.1 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase Ubie_methyltran PF01209.13 KXX82669.1 - 0.035 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 KXX82669.1 - 0.062 12.1 0.0 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.5 KXX82669.1 - 0.076 12.6 2.5 11 5.8 0.8 3.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Helitron_like_N PF14214.1 KXX82669.1 - 0.3 10.7 0.0 0.78 9.4 0.0 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus RrnaAD PF00398.15 KXX82669.1 - 0.87 8.5 0.0 1.6 7.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Asp PF00026.18 KXX82671.1 - 0.00017 20.9 0.0 0.0002 20.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SNF2_N PF00176.18 KXX82672.1 - 4.3e-62 209.6 0.0 5.8e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KXX82672.1 - 3.1e-07 30.3 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PBAN PF05874.6 KXX82672.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) zf-RING_5 PF14634.1 KXX82672.1 - 0.53 10.0 4.6 1.1 9.0 3.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AAA_19 PF13245.1 KXX82673.1 - 0.0033 17.1 0.0 0.013 15.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KXX82673.1 - 0.0073 15.3 0.0 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KXX82673.1 - 0.013 15.2 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KXX82673.1 - 0.025 14.5 0.1 0.025 14.5 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 KXX82673.1 - 0.065 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 KXX82673.1 - 0.087 12.2 1.6 0.47 9.8 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KXX82673.1 - 0.095 12.9 0.0 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KXX82673.1 - 0.15 12.8 0.4 1.4 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 KXX82674.1 - 2.5e-71 236.0 1.0 3e-20 72.3 0.0 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82674.1 - 8.9e-66 214.6 1.5 1.3e-07 31.0 0.0 11.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 KXX82674.1 - 1e-52 175.6 8.9 8.4e-11 42.0 0.0 8.8 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX82674.1 - 1.3e-48 161.8 2.9 2.6e-11 43.3 0.0 9.1 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82674.1 - 2.1e-47 154.3 0.4 0.00056 19.9 0.0 10.8 12 0 0 12 12 12 9 Ankyrin repeat Cation_ATPase_C PF00689.16 KXX82674.1 - 0.12 11.9 1.2 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Zn_clus PF00172.13 KXX82675.1 - 0.0017 18.2 6.5 0.002 18.0 2.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF382 PF04037.8 KXX82675.1 - 0.026 14.3 0.2 0.096 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Beta-lactamase PF00144.19 KXX82677.1 - 4.4e-35 121.2 0.1 6.1e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase zf-3CxxC PF13695.1 KXX82678.1 - 6.8e-20 71.1 0.0 9.3e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding domain Methyltransf_23 PF13489.1 KXX82679.1 - 3.8e-23 81.9 0.0 6.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82679.1 - 4.3e-12 46.3 0.0 1.1e-11 45.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82679.1 - 9.5e-09 35.6 0.0 7.2e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82679.1 - 1.2e-08 34.7 0.0 4e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82679.1 - 4.8e-08 33.5 0.0 9.4e-07 29.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82679.1 - 1.8e-07 30.5 0.0 2.4e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX82679.1 - 7.4e-06 26.2 0.0 2.7e-05 24.4 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX82679.1 - 0.00044 20.2 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KXX82679.1 - 0.00086 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KXX82679.1 - 0.0023 17.0 0.0 0.0054 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KXX82679.1 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KXX82679.1 - 0.0035 16.7 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 KXX82679.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 KXX82679.1 - 0.039 13.4 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KXX82679.1 - 0.045 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Gly-zipper_OmpA PF13436.1 KXX82681.1 - 0.001 18.7 0.3 0.001 18.7 0.2 1.9 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Dynamin_N PF00350.18 KXX82681.1 - 0.5 10.1 0.0 0.5 10.1 0.0 3.9 2 1 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 KXX82681.1 - 1.3 8.9 3.6 0.89 9.5 0.0 2.5 2 2 1 3 3 3 0 50S ribosome-binding GTPase Cupin_8 PF13621.1 KXX82682.1 - 2.5 7.5 5.0 4 6.8 3.5 1.3 1 0 0 1 1 1 0 Cupin-like domain Abhydrolase_6 PF12697.2 KXX82683.1 - 6.6e-20 71.9 4.2 8.4e-20 71.6 2.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82683.1 - 5.1e-05 23.0 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82683.1 - 0.037 13.5 1.9 0.085 12.3 0.6 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold MOSC_N PF03476.11 KXX82684.1 - 8.6e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KXX82684.1 - 2.7e-10 39.8 0.0 5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Fungal_trans PF04082.13 KXX82685.1 - 5.7e-16 58.1 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KXX82685.1 - 2.7e-09 36.8 13.6 0.00017 21.7 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX82685.1 - 6e-06 26.2 7.4 6e-06 26.2 5.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX82685.1 - 0.003 17.7 19.4 0.071 13.4 2.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KXX82685.1 - 0.074 13.2 1.2 0.2 11.8 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KXX82685.1 - 3.1 7.8 8.6 0.68 9.9 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FA_desaturase PF00487.19 KXX82686.1 - 5.1e-26 91.6 28.0 9.3e-26 90.8 19.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KXX82686.1 - 2.4e-09 37.3 0.0 3.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) GTP_EFTU PF00009.22 KXX82687.1 - 7.6e-21 74.3 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KXX82687.1 - 1.5e-14 53.9 0.0 3.6e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KXX82687.1 - 1.5e-10 41.0 0.6 1.5e-09 37.8 0.4 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KXX82687.1 - 0.00074 19.4 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KXX82687.1 - 0.0012 19.3 0.1 0.018 15.5 0.1 2.7 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 KXX82687.1 - 0.0027 17.1 0.7 0.38 10.2 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KXX82687.1 - 0.03 13.5 0.2 0.06 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU_D4 PF14578.1 KXX82687.1 - 0.055 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 KXX82687.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Dynamin family PIG-L PF02585.12 KXX82688.1 - 2e-26 92.9 0.0 3.5e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF202 PF02656.10 KXX82689.1 - 2.5 8.3 4.9 0.81 9.9 0.6 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Polysacc_deac_1 PF01522.16 KXX82690.1 - 2e-29 101.7 0.1 4e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2422 PF10337.4 KXX82691.1 - 6.4e-99 331.8 0.0 6.4e-99 331.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KXX82691.1 - 3.7e-17 62.4 16.2 3.7e-17 62.4 11.2 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KXX82691.1 - 3e-07 30.2 0.0 0.0026 17.3 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2421) ALMT PF11744.3 KXX82691.1 - 0.00065 18.4 5.5 0.0014 17.3 3.8 1.5 1 0 0 1 1 1 1 Aluminium activated malate transporter Pex14_N PF04695.8 KXX82692.1 - 1.7 8.6 6.6 3.7 7.5 0.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cutinase PF01083.17 KXX82693.1 - 3.7e-33 114.7 0.1 9.6e-29 100.3 0.0 2.1 2 0 0 2 2 2 2 Cutinase PE-PPE PF08237.6 KXX82693.1 - 0.0035 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 KXX82693.1 - 0.0043 16.5 0.1 0.0063 15.9 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.6 KXX82693.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 KXX82693.1 - 0.021 14.1 0.0 0.082 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KXX82693.1 - 0.12 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 KXX82693.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4516 PF14990.1 KXX82693.1 - 0.52 9.9 2.2 0.65 9.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) MerC PF03203.9 KXX82694.1 - 0.12 12.7 3.0 0.38 11.1 0.1 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein E1-E2_ATPase PF00122.15 KXX82695.1 - 7.1e-62 208.4 2.4 1.8e-61 207.1 1.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX82695.1 - 2.6e-29 103.1 0.0 2.8e-28 99.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX82695.1 - 6.8e-18 64.4 0.0 1.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 KXX82695.1 - 3.4e-17 62.5 13.2 5.8e-13 48.7 3.8 3.5 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 KXX82695.1 - 1.3e-12 47.0 0.6 5e-12 45.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KXX82695.1 - 2.7e-12 47.2 0.0 5.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX82695.1 - 0.0029 17.2 0.4 0.0048 16.4 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase adh_short PF00106.20 KXX82696.1 - 1.5e-15 57.4 0.2 1.2e-13 51.2 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KXX82696.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX82696.1 - 0.0048 16.7 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pectate_lyase_3 PF12708.2 KXX82698.1 - 5.6e-83 278.4 6.9 3.3e-67 226.8 0.8 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KXX82698.1 - 1.1e-06 27.9 2.2 0.03 13.7 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase HET PF06985.6 KXX82699.1 - 3.2e-26 92.1 0.0 6.6e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 KXX82699.1 - 0.011 15.2 14.1 0.011 15.2 9.8 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type ApbA_C PF08546.6 KXX82700.1 - 1.3e-32 112.4 0.1 2.2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KXX82700.1 - 2.4e-24 85.5 0.0 8.1e-24 83.7 0.0 2.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KXX82700.1 - 0.1 12.3 0.0 0.46 10.2 0.0 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_hydro_7 PF00840.15 KXX82701.1 - 3.5e-141 470.5 2.7 4.3e-141 470.2 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FAD_binding_3 PF01494.14 KXX82702.1 - 1.1e-16 60.9 3.8 3.6e-10 39.4 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KXX82702.1 - 2.5e-09 36.5 0.2 4.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX82702.1 - 9.8e-09 34.5 0.1 1.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KXX82702.1 - 2.7e-07 30.6 0.1 2e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX82702.1 - 3.7e-07 28.9 0.3 9.9e-05 20.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KXX82702.1 - 6.9e-07 29.1 0.1 2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KXX82702.1 - 3e-05 23.2 0.6 0.00013 21.1 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KXX82702.1 - 0.0004 19.3 0.1 0.0025 16.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KXX82702.1 - 0.00058 19.9 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KXX82702.1 - 0.00062 18.7 0.1 0.054 12.4 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KXX82702.1 - 0.00077 19.0 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KXX82702.1 - 0.0014 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KXX82702.1 - 0.0076 16.6 0.1 0.12 12.8 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KXX82702.1 - 0.012 14.6 0.0 2 7.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KXX82702.1 - 0.078 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KXX82702.1 - 0.1 12.6 0.2 0.74 9.7 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_9 PF13454.1 KXX82702.1 - 0.13 12.0 0.1 16 5.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KXX82702.1 - 0.37 9.3 2.8 0.71 8.4 0.1 2.5 3 1 1 4 4 4 0 Tryptophan halogenase p450 PF00067.17 KXX82703.1 - 6.5e-49 166.6 0.0 1.2e-48 165.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KXX82703.1 - 8.7e-15 54.5 0.0 2.1e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX82703.1 - 5.9e-07 29.6 0.0 1.9e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF747 PF05346.6 KXX82705.1 - 1.5e-134 448.2 1.5 1.9e-134 447.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3886 PF13025.1 KXX82705.1 - 0.098 12.6 6.4 0.27 11.2 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Amnionless PF14828.1 KXX82705.1 - 0.42 9.0 0.2 0.81 8.1 0.0 1.5 2 0 0 2 2 2 0 Amnionless Acetyltransf_1 PF00583.19 KXX82706.1 - 1.6e-09 37.6 0.1 3.5e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KXX82706.1 - 7.8e-05 22.7 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KXX82706.1 - 0.00012 22.1 0.1 0.00019 21.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 KXX82707.1 - 1e-66 225.4 0.0 1.4e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C32 PF05411.7 KXX82707.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase Sugar_tr PF00083.19 KXX82708.1 - 3.1e-64 217.2 16.5 5.3e-64 216.4 11.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX82708.1 - 6.5e-15 54.7 25.5 2.4e-13 49.5 1.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 KXX82708.1 - 3 7.1 11.8 0.12 11.6 0.6 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1129) Aldedh PF00171.17 KXX82709.1 - 3.2e-157 523.5 1.1 3.6e-157 523.4 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KXX82709.1 - 0.0024 16.6 0.1 0.0056 15.4 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KXX82709.1 - 0.011 14.9 0.1 0.097 11.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) FAD_binding_3 PF01494.14 KXX82710.1 - 2.1e-13 50.1 0.2 3.9e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KXX82710.1 - 9.2e-07 28.8 0.2 3e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX82710.1 - 9.4e-07 28.0 0.1 1.8e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX82710.1 - 4.8e-06 25.7 1.1 0.00031 19.7 0.3 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX82710.1 - 3.4e-05 24.1 0.1 0.0012 19.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX82710.1 - 3.8e-05 23.6 0.1 9.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KXX82710.1 - 9.6e-05 21.3 0.0 0.00022 20.2 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KXX82710.1 - 0.00022 19.8 0.0 0.0012 17.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KXX82710.1 - 0.00023 20.4 0.1 0.0004 19.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KXX82710.1 - 0.00085 18.0 0.1 0.75 8.3 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KXX82710.1 - 0.023 14.2 0.1 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KXX82710.1 - 0.04 13.9 0.1 0.49 10.4 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX82710.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amidohydro_2 PF04909.9 KXX82711.1 - 2.2e-39 135.6 1.5 3e-39 135.2 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase NACHT PF05729.7 KXX82712.1 - 1.9e-13 50.3 5.2 2.1e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KXX82712.1 - 0.00018 21.6 0.1 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KXX82712.1 - 0.0013 19.0 0.3 0.0083 16.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 KXX82712.1 - 0.007 16.5 0.0 0.029 14.5 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KXX82712.1 - 0.023 14.1 1.2 0.13 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KXX82712.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 KXX82712.1 - 0.057 13.2 0.0 0.51 10.2 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 KXX82712.1 - 0.099 13.0 0.0 0.43 10.9 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) AAA_23 PF13476.1 KXX82712.1 - 0.12 12.6 3.1 0.76 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KXX82712.1 - 0.29 11.9 2.1 0.88 10.4 0.2 2.9 2 1 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.10 KXX82712.1 - 1 8.4 9.4 1.9 7.5 6.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLH PF01738.13 KXX82713.1 - 7.2e-29 100.6 0.0 8.3e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KXX82713.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KXX82713.1 - 0.012 14.7 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 KXX82713.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family BsuPI PF12690.2 KXX82713.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Glyco_hydro_10 PF00331.15 KXX82714.1 - 1e-92 310.6 0.0 1.2e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Ferric_reduct PF01794.14 KXX82715.1 - 1.3e-14 54.3 16.3 1.3e-14 54.3 11.3 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KXX82715.1 - 1.7e-08 34.3 0.0 4.8e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KXX82715.1 - 7.8e-06 25.8 0.6 0.15 11.9 0.3 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Cyt-b5 PF00173.23 KXX82716.1 - 9.6e-15 54.1 0.0 2.5e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 KXX82716.1 - 5.4e-13 48.1 0.0 4.1e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 KXX82716.1 - 1.1e-12 47.9 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KXX82716.1 - 1.4e-08 35.2 0.0 3.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain 2-Hacid_dh_C PF02826.14 KXX82717.1 - 5.1e-45 152.7 0.0 6.4e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX82717.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KXX82717.1 - 0.029 14.6 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.16 KXX82717.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SAICAR_synt PF01259.13 KXX82718.1 - 2.2e-79 266.1 0.0 2.8e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase HEAT_EZ PF13513.1 KXX82719.1 - 9.8e-19 67.2 16.0 6.6e-06 26.4 0.1 12.4 9 2 4 13 13 13 4 HEAT-like repeat HEAT_2 PF13646.1 KXX82719.1 - 9.2e-15 54.7 25.3 0.00057 20.1 0.0 8.7 3 2 6 9 9 9 6 HEAT repeats HEAT PF02985.17 KXX82719.1 - 2.2e-14 52.1 9.6 0.003 17.5 0.0 9.3 10 0 0 10 10 9 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KXX82719.1 - 4.4e-09 36.6 0.1 0.36 11.2 0.0 5.7 5 2 1 6 6 5 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KXX82719.1 - 1.6e-08 34.3 1.3 1.2e-07 31.4 0.2 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.7 KXX82719.1 - 8.2e-06 25.5 0.0 2.4 7.7 0.0 4.1 4 0 0 4 4 4 3 rRNA processing/ribosome biogenesis ParcG PF10274.4 KXX82719.1 - 4.4e-05 23.4 0.9 0.43 10.4 0.0 4.6 4 1 0 5 5 5 1 Parkin co-regulated protein Cnd1 PF12717.2 KXX82719.1 - 0.00022 21.1 0.1 6.2 6.6 0.0 4.5 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KXX82719.1 - 0.00032 20.1 0.2 0.019 14.3 0.0 3.6 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.18 KXX82719.1 - 0.0093 15.7 7.5 15 5.6 0.0 6.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Amidohydro_1 PF01979.15 KXX82719.1 - 0.022 14.4 0.1 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase family 2CSK_N PF08521.5 KXX82720.1 - 0.04 13.4 0.1 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 Two-component sensor kinase N-terminal F-box-like PF12937.2 KXX82722.1 - 5.8e-08 32.3 2.1 1.5e-07 31.0 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX82722.1 - 5.3e-05 22.7 1.6 0.00011 21.7 1.1 1.6 1 0 0 1 1 1 1 F-box domain 7tm_2 PF00002.19 KXX82723.1 - 0.12 11.3 6.0 0.23 10.5 4.1 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Abhydrolase_3 PF07859.8 KXX82725.1 - 6.5e-40 136.9 0.0 8.2e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KXX82725.1 - 2.1e-06 26.7 0.0 3.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KXX82725.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KXX82725.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.15 KXX82726.1 - 6.4e-76 255.2 0.0 1e-75 254.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KXX82726.1 - 5.3e-24 84.5 0.0 7.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 KXX82726.1 - 1.8e-07 30.8 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KXX82726.1 - 0.0047 16.1 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Mrr_cat_2 PF13156.1 KXX82727.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease DUF3328 PF11807.3 KXX82728.1 - 1.8e-40 138.9 2.1 2.2e-40 138.6 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GMC_oxred_N PF00732.14 KXX82729.1 - 4.2e-58 196.8 0.0 5.9e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX82729.1 - 1.5e-35 122.6 0.0 4.3e-35 121.1 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KXX82729.1 - 8.2e-10 38.1 0.4 6.6e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KXX82729.1 - 1.1e-08 34.4 1.0 6.6e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KXX82729.1 - 0.00029 20.7 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX82729.1 - 0.00033 20.7 0.5 0.015 15.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX82729.1 - 0.00069 18.1 0.2 0.4 9.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 KXX82729.1 - 0.0037 17.2 0.1 0.013 15.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX82729.1 - 0.027 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KXX82729.1 - 0.029 13.4 0.1 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KXX82729.1 - 0.032 13.2 0.2 0.16 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KXX82729.1 - 0.059 13.1 0.1 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KXX82729.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain RTA1 PF04479.8 KXX82731.1 - 1.9e-49 168.1 7.0 2.9e-49 167.6 4.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Ank_2 PF12796.2 KXX82733.1 - 4.3e-39 132.7 0.2 3.7e-16 59.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82733.1 - 6.6e-37 123.4 4.0 5.1e-08 32.3 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 KXX82733.1 - 2.4e-23 79.8 0.0 0.0023 18.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KXX82733.1 - 5.3e-20 70.9 4.5 5.7e-09 35.9 0.1 6.2 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX82733.1 - 7.6e-18 64.5 0.1 1.2e-05 25.6 0.0 5.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) DUF1996 PF09362.5 KXX82734.1 - 2.7e-92 308.6 0.6 4e-92 308.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NUDIX PF00293.23 KXX82734.1 - 1e-13 51.0 1.6 1.1e-13 51.0 0.2 1.8 1 1 1 2 2 2 1 NUDIX domain GFO_IDH_MocA PF01408.17 KXX82735.1 - 9.2e-17 61.6 0.0 1.7e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1132 PF06575.7 KXX82735.1 - 0.17 12.1 0.0 0.48 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) SH3_9 PF14604.1 KXX82736.1 - 4.8e-14 51.6 0.4 2.1e-09 36.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KXX82736.1 - 1.6e-06 27.4 0.4 0.0013 18.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KXX82736.1 - 0.0011 18.3 1.5 0.0077 15.6 0.1 2.4 2 0 0 2 2 2 1 SH3 domain Val_tRNA-synt_C PF10458.4 KXX82737.1 - 0.12 12.4 0.8 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm TPR_6 PF13174.1 KXX82737.1 - 0.14 12.6 0.1 1.8 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1996 PF09362.5 KXX82738.1 - 8.9e-54 182.6 0.1 1.1e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 KXX82740.1 - 5.1e-89 297.9 2.0 6.9e-89 297.5 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MFS_1 PF07690.11 KXX82741.1 - 1.2e-08 34.1 27.0 1.2e-08 34.1 18.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3278 PF11683.3 KXX82741.1 - 0.6 10.1 2.8 0.69 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Asp PF00026.18 KXX82742.1 - 1.1e-32 113.5 0.0 5.5e-32 111.2 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KXX82742.1 - 2.1e-05 24.9 0.1 4.1 7.9 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 KXX82742.1 - 0.00048 19.6 0.0 0.0044 16.5 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RVP PF00077.15 KXX82742.1 - 0.031 14.1 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease GSDH PF07995.6 KXX82743.1 - 6.3e-05 22.2 0.0 0.00019 20.6 0.0 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KXX82743.1 - 7e-05 22.3 0.1 0.29 10.4 0.0 2.4 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KXX82743.1 - 0.0026 17.6 0.1 16 5.6 0.0 5.1 5 0 0 5 5 5 1 NHL repeat RCC1_2 PF13540.1 KXX82743.1 - 1.7 8.3 16.8 0.7 9.5 0.7 4.8 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat Acetyltransf_2 PF00797.12 KXX82744.1 - 1.9e-44 152.0 0.0 2.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF4448 PF14610.1 KXX82745.1 - 3.3e-29 101.7 0.0 4.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KXX82745.1 - 0.00024 20.3 1.9 0.00049 19.3 1.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GAPT PF11770.3 KXX82745.1 - 0.03 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) K_oxygenase PF13434.1 KXX82746.1 - 1.4e-106 356.3 0.0 1.7e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KXX82746.1 - 6.6e-10 39.3 0.0 1.7e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX82746.1 - 1.3e-09 38.0 0.0 1.7e-08 34.3 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KXX82746.1 - 0.00018 21.4 0.0 0.00046 20.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 KXX82746.1 - 0.035 13.2 0.0 7 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Condensation PF00668.15 KXX82747.1 - 3.1e-132 439.9 0.0 4.1e-29 101.3 0.0 6.5 6 1 0 6 6 6 5 Condensation domain AMP-binding PF00501.23 KXX82747.1 - 5.7e-93 311.5 0.0 9.3e-93 310.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KXX82747.1 - 9.2e-33 112.3 1.8 8e-10 38.8 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX82747.1 - 0.00025 21.9 0.0 0.00075 20.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KXX82747.1 - 0.015 13.7 0.0 0.38 9.1 0.0 2.3 2 0 0 2 2 2 0 Transferase family AATase PF07247.7 KXX82747.1 - 0.029 12.9 0.0 11 4.4 0.0 3.2 3 0 0 3 3 3 0 Alcohol acetyltransferase WW PF00397.21 KXX82748.1 - 2.5e-09 36.8 4.8 2.5e-09 36.8 3.4 3.2 4 0 0 4 4 4 1 WW domain FF PF01846.14 KXX82748.1 - 7.5e-08 32.2 0.3 7.5e-08 32.2 0.2 3.2 3 0 0 3 3 3 1 FF domain Alpha_GJ PF03229.8 KXX82749.1 - 0.26 11.6 5.7 0.5 10.7 4.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J IncA PF04156.9 KXX82749.1 - 2.4 7.7 5.7 3.2 7.3 4.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1264 PF06884.6 KXX82750.1 - 4.7e-71 237.7 0.0 5.5e-71 237.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) SET PF00856.23 KXX82751.1 - 0.031 14.5 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 SET domain Ras PF00071.17 KXX82752.1 - 1.3e-65 219.6 0.5 1.6e-65 219.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX82752.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX82752.1 - 2.6e-16 59.3 0.1 3.1e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX82752.1 - 2e-05 23.8 0.1 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KXX82752.1 - 2.8e-05 23.6 0.2 6.3e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX82752.1 - 7.1e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KXX82752.1 - 0.00034 19.8 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KXX82752.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KXX82752.1 - 0.0013 18.9 0.1 0.096 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 KXX82752.1 - 0.0029 16.8 0.0 0.021 14.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KXX82752.1 - 0.0094 15.1 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX82752.1 - 0.019 14.9 0.1 0.084 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KXX82752.1 - 0.022 14.6 0.2 0.069 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KXX82752.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KXX82752.1 - 0.041 12.9 0.1 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 KXX82752.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KXX82752.1 - 0.081 13.2 0.1 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KXX82752.1 - 0.096 12.1 0.0 0.95 8.9 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Kinesin PF00225.18 KXX82754.1 - 1.5e-93 313.1 0.0 1.5e-93 313.1 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain AMP-binding PF00501.23 KXX82755.1 - 4.6e-91 305.2 0.2 5.5e-91 305.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX82755.1 - 6e-21 75.1 2.8 1.3e-19 70.8 0.3 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 KXX82756.1 - 1.4e-28 98.7 0.2 2.6e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX82756.1 - 7.2e-26 90.2 0.0 1.6e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX82756.1 - 9.6e-05 23.2 0.0 0.00019 22.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KXX82756.1 - 0.085 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2226 PF09987.4 KXX82756.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) NAD_binding_10 PF13460.1 KXX82756.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Actin PF00022.14 KXX82757.1 - 6e-87 291.6 0.0 1.3e-86 290.5 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KXX82757.1 - 0.12 10.8 0.1 3 6.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KXX82758.1 - 3.6e-29 101.4 3.5 3.2e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Reprolysin_5 PF13688.1 KXX82760.1 - 2.9e-61 206.8 4.5 9.9e-61 205.0 3.1 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX82760.1 - 9.7e-45 152.7 1.0 9.7e-45 152.7 0.7 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KXX82760.1 - 1.7e-44 151.8 0.4 3.1e-44 150.9 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KXX82760.1 - 8.6e-19 68.2 0.0 2.3e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KXX82760.1 - 3.9e-18 65.4 31.6 3.9e-18 65.4 21.9 4.5 2 1 2 4 4 4 1 Disintegrin Reprolysin PF01421.14 KXX82760.1 - 1.2e-05 25.0 11.6 1.2e-05 25.0 8.1 3.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KXX82760.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide TPR_1 PF00515.23 KXX82761.1 - 1e-54 179.9 28.1 4.2e-08 32.4 0.0 10.4 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 KXX82761.1 - 1e-50 165.5 21.5 4.8e-06 26.0 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KXX82761.1 - 2e-46 155.4 43.5 2.2e-11 43.2 1.1 6.3 1 1 6 8 8 8 8 TPR repeat TPR_8 PF13181.1 KXX82761.1 - 6.6e-39 128.7 19.1 2.5e-06 26.8 0.6 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 KXX82761.1 - 1e-34 118.4 21.4 2.4e-08 34.4 0.1 6.7 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 KXX82761.1 - 3.4e-30 101.7 19.0 0.00021 21.6 0.0 9.7 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KXX82761.1 - 1.2e-29 101.9 24.4 3.2e-06 26.9 1.3 7.6 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 KXX82761.1 - 1.3e-27 93.5 20.8 0.001 19.0 0.1 10.5 10 1 1 11 11 10 6 Tetratricopeptide repeat TPR_6 PF13174.1 KXX82761.1 - 5.3e-24 82.9 15.2 0.013 15.8 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 KXX82761.1 - 1.3e-22 77.7 12.4 0.0031 17.1 0.0 9.7 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KXX82761.1 - 6.6e-22 77.6 20.5 1.3e-05 25.4 0.4 6.9 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.1 KXX82761.1 - 5.4e-15 54.9 16.8 0.0022 17.8 0.3 6.9 1 1 5 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KXX82761.1 - 5.5e-15 55.2 12.4 6.5e-08 32.6 2.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KXX82761.1 - 1.6e-12 47.0 9.9 5e-05 22.4 1.2 4.1 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KXX82761.1 - 1.3e-05 25.1 2.0 0.2 11.7 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.12 KXX82761.1 - 0.082 13.2 10.3 9.9 6.4 0.5 3.9 3 1 0 4 4 3 0 Bacterial transcriptional activator domain TPR_21 PF09976.4 KXX82761.1 - 0.11 12.4 17.1 0.9 9.4 0.0 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat GAS PF13851.1 KXX82761.1 - 0.13 11.4 0.1 0.26 10.4 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2852 PF11014.3 KXX82761.1 - 0.18 11.7 0.6 0.43 10.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_10 PF13374.1 KXX82761.1 - 0.2 11.6 20.1 19 5.3 0.1 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 KXX82761.1 - 0.96 8.1 2.4 4.4 5.9 0.2 2.8 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 KXX82761.1 - 3.2 7.7 16.1 3.9 7.4 0.8 5.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.17 KXX82762.1 - 4.6e-117 390.0 9.4 5.6e-117 389.8 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 UNC45-central PF11701.3 KXX82764.1 - 1.4e-48 164.5 0.0 6.7e-48 162.2 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KXX82764.1 - 0.0026 17.9 18.2 0.63 10.3 3.4 5.4 3 1 2 5 5 5 2 HEAT repeats ERCC4 PF02732.10 KXX82765.1 - 6.7e-19 68.0 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Tfb4 PF03850.9 KXX82766.1 - 1.4e-83 280.3 6.9 4.2e-60 203.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor Tfb4 tRNA_int_end_N2 PF12928.2 KXX82768.1 - 3e-11 42.6 0.9 1.3e-10 40.5 0.6 2.0 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KXX82768.1 - 0.049 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain WW PF00397.21 KXX82769.1 - 2.2e-07 30.6 0.2 6.9e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 WW domain Spot_14 PF07084.7 KXX82769.1 - 0.24 11.2 0.8 0.37 10.6 0.6 1.2 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 GDPD PF03009.12 KXX82770.1 - 6.4e-71 238.8 0.0 1.5e-70 237.6 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KXX82770.1 - 9.6e-33 112.3 1.6 1.5e-12 47.6 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX82770.1 - 5.1e-32 109.6 4.2 1.1e-10 41.7 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 KXX82770.1 - 3.4e-27 95.9 8.6 1.2e-14 54.7 0.2 4.2 3 1 1 4 4 4 2 SPX domain Ank PF00023.25 KXX82770.1 - 3.8e-27 92.6 6.7 1.7e-07 30.6 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KXX82770.1 - 5.3e-25 86.8 3.4 3.3e-07 30.3 0.0 6.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82770.1 - 7e-15 53.6 3.4 0.00037 20.4 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat ABC_membrane_2 PF06472.10 KXX82771.1 - 1.9e-109 365.1 1.8 1.9e-109 365.1 1.2 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KXX82771.1 - 1.3e-16 61.1 0.0 3.4e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KXX82771.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX82771.1 - 0.0078 16.2 0.1 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KXX82771.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KXX82771.1 - 0.041 14.2 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KXX82771.1 - 0.06 12.4 0.1 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 KXX82771.1 - 0.084 12.0 0.1 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KXX82771.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pga1 PF10333.4 KXX82772.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Rpr2 PF04032.11 KXX82773.1 - 4.1e-09 36.1 0.1 8.2e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 KXX82773.1 - 0.1 12.3 2.4 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal DUF3133 PF11331.3 KXX82773.1 - 0.72 9.4 3.7 8.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-ZPR1 PF03367.8 KXX82774.1 - 1.7e-103 342.6 0.5 6e-51 171.7 0.1 2.5 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Death PF00531.17 KXX82775.1 - 0.087 12.5 0.0 3 7.6 0.0 2.8 2 0 0 2 2 2 0 Death domain DUF866 PF05907.8 KXX82776.1 - 2.6e-49 166.8 0.0 2.8e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3716 PF12511.3 KXX82776.1 - 0.048 13.2 1.8 0.083 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) GF_recep_IV PF14843.1 KXX82776.1 - 0.056 13.0 0.5 0.075 12.6 0.4 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV PHD PF00628.24 KXX82776.1 - 0.069 12.8 0.9 0.16 11.7 0.6 1.6 1 0 0 1 1 1 0 PHD-finger Lar_restr_allev PF14354.1 KXX82776.1 - 0.14 12.4 1.0 2.7 8.3 0.7 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_5 PF13719.1 KXX82776.1 - 1.2 8.7 4.2 3 7.5 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KXX82776.1 - 1.7 8.4 4.7 3.9 7.2 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain RabGAP-TBC PF00566.13 KXX82777.1 - 7.7e-41 139.9 0.0 2.6e-39 134.9 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ank PF00023.25 KXX82779.1 - 4.8e-33 111.3 5.2 1.9e-09 36.8 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KXX82779.1 - 7.9e-33 111.7 7.8 7.6e-11 41.8 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KXX82779.1 - 2.1e-32 111.2 1.4 3.2e-23 81.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX82779.1 - 2.2e-27 94.9 0.6 2.3e-10 40.6 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82779.1 - 2.9e-27 92.0 0.5 7.1e-06 25.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat PEGA PF08308.6 KXX82779.1 - 0.00035 20.3 0.0 0.65 9.8 0.0 3.4 1 1 2 3 3 3 1 PEGA domain Imm_superinfect PF14373.1 KXX82779.1 - 0.0013 18.2 0.0 5.3 6.7 0.0 3.1 3 0 0 3 3 3 1 Superinfection immunity protein Cpl-7 PF08230.6 KXX82779.1 - 0.003 17.2 0.1 5 6.9 0.0 3.2 3 0 0 3 3 3 1 Cpl-7 lysozyme C-terminal domain Dioxygenase_N PF04444.9 KXX82779.1 - 0.083 12.8 1.7 0.69 9.9 1.2 2.3 1 1 0 1 1 1 0 Catechol dioxygenase N terminus DUF2984 PF11203.3 KXX82779.1 - 0.12 12.4 2.3 2 8.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) Clp_N PF02861.15 KXX82779.1 - 1 9.3 5.0 8.4 6.4 0.2 3.1 2 1 1 3 3 3 0 Clp amino terminal domain ATP-grasp_2 PF08442.5 KXX82780.1 - 5.4e-78 261.0 0.5 5.4e-78 261.0 0.3 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KXX82780.1 - 7.9e-27 93.7 0.5 1.6e-26 92.7 0.4 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KXX82780.1 - 3.9e-07 29.5 0.7 1.2e-06 27.8 0.2 2.1 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KXX82780.1 - 0.00051 19.6 1.5 0.012 15.1 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KXX82780.1 - 0.00087 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KXX82780.1 - 0.043 13.2 0.0 0.62 9.4 0.0 2.6 1 1 2 3 3 3 0 RimK-like ATP-grasp domain HeLo PF14479.1 KXX82781.1 - 0.016 14.9 0.5 0.028 14.1 0.3 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation WHIM1 PF15612.1 KXX82781.1 - 0.096 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 tRNA-synt_2c PF01411.14 KXX82781.1 - 0.14 10.4 0.1 0.21 9.8 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Ank PF00023.25 KXX82782.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 KXX82782.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX82782.1 - 0.036 14.2 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 KXX82782.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3883 PF13020.1 KXX82783.1 - 0.00014 21.5 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HCR PF07111.7 KXX82783.1 - 0.026 12.5 0.8 0.039 11.9 0.5 1.2 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) HATPase_c_3 PF13589.1 KXX82784.1 - 0.00014 21.4 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KXX82784.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUKH_5 PF14567.1 KXX82784.1 - 0.11 11.9 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall MAPEG PF01124.13 KXX82785.1 - 2.1e-17 62.9 1.4 2.6e-17 62.6 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Alpha-2-MRAP_C PF06401.6 KXX82785.1 - 0.051 13.4 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain CitG PF01874.11 KXX82786.1 - 0.012 14.8 0.2 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase AP_endonuc_2_N PF07582.7 KXX82786.1 - 0.1 12.1 1.1 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus Pro_isomerase PF00160.16 KXX82787.1 - 3.3e-45 154.0 0.0 3.8e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 KXX82788.1 - 2.9e-14 53.3 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Aldose_epim PF01263.15 KXX82789.1 - 5.9e-48 163.5 0.1 8.5e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Ctf8 PF09696.5 KXX82789.1 - 5.1e-23 81.1 0.0 7.7e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Ctf8 ATP-synt_ab PF00006.20 KXX82790.1 - 4.5e-61 206.0 0.0 6e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KXX82790.1 - 2e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KXX82790.1 - 5.3e-12 45.7 0.9 1.1e-11 44.7 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KXX82790.1 - 0.00022 21.0 0.4 0.00048 19.9 0.3 1.5 1 0 0 1 1 1 1 HAS barrel domain NST1 PF13945.1 KXX82791.1 - 0.059 13.4 4.0 0.11 12.5 2.8 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator WD40 PF00400.27 KXX82792.1 - 2.8e-15 55.5 19.5 4.2e-05 23.2 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Sigma70_r1_2 PF00140.15 KXX82792.1 - 0.026 14.2 0.3 0.049 13.3 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Nup160 PF11715.3 KXX82792.1 - 0.032 12.3 0.6 0.078 11.1 0.0 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nop14 PF04147.7 KXX82793.1 - 0.87 7.4 7.9 1.2 6.9 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family G_glu_transpept PF01019.16 KXX82794.1 - 3.8e-154 513.9 0.1 4.7e-154 513.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase P22_CoatProtein PF11651.3 KXX82794.1 - 0.018 13.6 0.1 0.026 13.1 0.1 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Ribosomal_S8e PF01201.17 KXX82795.1 - 9.3e-41 139.0 0.2 1.2e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.7 KXX82796.1 - 1.5e-118 395.8 0.0 1.5e-118 395.8 0.0 4.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KXX82796.1 - 3.6e-97 325.3 0.1 6.7e-97 324.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KXX82796.1 - 2.9e-90 302.9 0.0 2.9e-90 302.9 0.0 3.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KXX82796.1 - 9e-34 115.6 8.9 9e-34 115.6 6.2 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF4414) Pro_isomerase PF00160.16 KXX82797.1 - 3.7e-42 144.1 0.0 6.6e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PRP38_assoc PF12871.2 KXX82797.1 - 0.0012 19.3 33.8 0.0012 19.3 23.4 3.2 3 1 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HSF_DNA-bind PF00447.12 KXX82798.1 - 5.7e-28 97.1 0.2 1.4e-27 95.8 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_S6e PF01092.14 KXX82799.1 - 2.4e-59 198.4 0.0 5.2e-59 197.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 KXX82799.1 - 1.2 9.3 4.3 2.8 8.1 3.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Diphthamide_syn PF01866.12 KXX82800.1 - 7.1e-112 373.6 0.0 8.5e-112 373.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein WD40 PF00400.27 KXX82801.1 - 1.1e-24 85.3 6.1 4.2e-08 32.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 KXX82801.1 - 6.2e-09 35.6 1.3 6.2e-09 35.6 0.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KXX82801.1 - 1.6e-05 23.9 0.0 0.00022 20.1 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KXX82801.1 - 0.001 18.8 0.0 0.014 15.1 0.0 2.4 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KXX82801.1 - 0.0041 15.0 0.1 0.011 13.6 0.1 1.5 1 1 0 1 1 1 1 IKI3 family HSF_DNA-bind PF00447.12 KXX82802.1 - 9.8e-36 122.0 1.1 1.6e-35 121.3 0.7 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding p450 PF00067.17 KXX82803.1 - 1.1e-50 172.4 0.0 1e-44 152.8 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 F-box-like PF12937.2 KXX82804.1 - 0.0077 15.9 0.2 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX82804.1 - 2 8.1 6.3 9.5 6.0 0.0 2.8 3 0 0 3 3 3 0 F-box domain Trp_halogenase PF04820.9 KXX82805.1 - 1.7e-27 96.1 0.3 2.4e-12 46.2 0.2 3.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KXX82805.1 - 2.8e-10 39.7 0.0 8e-10 38.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KXX82805.1 - 1.9e-06 27.0 0.8 0.0011 17.9 0.3 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KXX82805.1 - 4.2e-06 26.0 0.0 8.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KXX82805.1 - 5.2e-06 26.4 0.0 9.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX82805.1 - 3e-05 23.9 0.2 0.00024 21.0 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX82805.1 - 0.00075 18.4 0.1 0.0013 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KXX82805.1 - 0.00076 18.4 0.1 0.0013 17.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KXX82805.1 - 0.0025 16.3 0.1 0.0039 15.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KXX82805.1 - 0.0044 17.0 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KXX82805.1 - 0.059 13.1 0.7 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 ThiF family UbiA PF01040.13 KXX82806.1 - 2.7e-18 66.1 30.2 4.6e-18 65.3 20.3 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family Fig1 PF12351.3 KXX82806.1 - 0.016 15.1 2.9 2 8.2 0.0 3.2 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 AMP-binding PF00501.23 KXX82807.1 - 3.1e-36 124.6 0.0 5.7e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KXX82807.1 - 3.4e-20 72.0 0.0 4.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KXX82807.1 - 3e-08 33.3 0.0 1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KXX82807.1 - 2.4e-05 24.5 0.1 0.00062 19.9 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 KXX82807.1 - 0.0068 16.3 0.0 0.054 13.4 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase eIF-5_eIF-2B PF01873.12 KXX82809.1 - 2.8e-44 149.7 0.2 4.8e-44 149.0 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KXX82809.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.1 KXX82809.1 - 0.15 11.8 0.4 23 4.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon DNA_RNApol_7kD PF03604.8 KXX82809.1 - 0.16 11.4 1.2 0.39 10.2 0.8 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 KXX82809.1 - 3.5 7.8 7.5 2 8.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain NmrA PF05368.8 KXX82810.1 - 4.4e-11 42.4 0.0 1.9e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KXX82810.1 - 1.3e-08 35.1 0.0 3.2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KXX82810.1 - 6.9e-05 21.9 0.0 9.5e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KXX82810.1 - 0.0027 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KXX82810.1 - 0.018 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain A_deaminase PF00962.17 KXX82811.1 - 2.1e-19 69.6 0.0 8.6e-19 67.6 0.0 1.9 1 1 0 2 2 2 1 Adenosine/AMP deaminase DAO PF01266.19 KXX82812.1 - 9.5e-51 172.7 0.3 1.5e-50 172.1 0.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX82812.1 - 9.7e-06 25.5 0.1 2.9e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX82812.1 - 2.2e-05 23.5 0.2 0.00063 18.7 0.1 2.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KXX82812.1 - 0.00043 19.4 0.1 0.00064 18.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX82812.1 - 0.00095 19.2 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX82812.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX82812.1 - 0.0034 15.9 0.0 1.7 6.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KXX82812.1 - 0.0038 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KXX82812.1 - 0.11 12.3 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2477 PF10631.4 KXX82814.1 - 0.065 13.4 6.8 0.14 12.3 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) Abhydro_lipase PF04083.11 KXX82815.1 - 5.9e-20 70.3 0.0 1.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KXX82815.1 - 3.3e-06 27.1 1.6 6.9e-06 26.1 0.2 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82815.1 - 0.00037 20.2 0.0 0.00067 19.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX82815.1 - 0.048 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1237 PF06824.6 KXX82816.1 - 3.7e-180 599.0 0.0 4.3e-180 598.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CoxIIa PF08113.6 KXX82816.1 - 0.16 11.6 0.8 0.32 10.7 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family SH3BGR PF04908.10 KXX82817.1 - 3e-05 23.8 0.0 7.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein TFIIA PF03153.8 KXX82817.1 - 2.6 7.8 6.0 3.3 7.4 4.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.24 KXX82818.1 - 6.4e-50 168.7 0.0 2.7e-43 147.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX82818.1 - 6.3e-05 22.4 0.2 0.00052 19.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KXX82818.1 - 7.9e-05 23.4 0.3 0.00041 21.1 0.0 2.4 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KXX82818.1 - 0.00017 20.7 0.0 0.00058 18.9 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KXX82818.1 - 0.00066 18.6 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KXX82818.1 - 0.00068 19.7 0.5 0.0044 17.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KXX82818.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KXX82818.1 - 0.0018 17.9 0.1 0.017 14.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KXX82818.1 - 0.0028 17.5 0.0 0.0073 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KXX82818.1 - 0.003 17.5 4.2 0.028 14.4 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.17 KXX82818.1 - 0.0053 16.9 0.0 0.031 14.4 0.0 2.4 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KXX82818.1 - 0.0099 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KXX82818.1 - 0.015 15.0 0.0 0.069 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KXX82818.1 - 0.016 14.3 0.1 0.046 12.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KXX82818.1 - 0.025 13.8 0.1 0.074 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 KXX82818.1 - 0.026 13.6 0.0 0.072 12.1 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KXX82818.1 - 0.034 14.4 0.2 0.17 12.1 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KXX82818.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 KXX82818.1 - 0.04 13.8 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KXX82818.1 - 0.057 13.2 0.0 0.24 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KXX82818.1 - 0.077 12.4 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KXX82818.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 KXX82818.1 - 0.29 9.7 0.0 0.47 8.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NACHT PF05729.7 KXX82818.1 - 0.42 10.2 1.1 2.2 7.9 0.0 2.8 4 0 0 4 4 2 0 NACHT domain AAA_24 PF13479.1 KXX82818.1 - 3.2 7.2 5.8 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain PNGaseA PF12222.3 KXX82819.1 - 6.7e-133 443.6 1.2 8.6e-133 443.3 0.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A AMP-binding PF00501.23 KXX82820.1 - 3.3e-289 958.0 0.0 1.9e-99 332.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KXX82820.1 - 5.8e-213 705.0 10.0 8.1e-76 254.7 1.3 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KXX82820.1 - 5.3e-43 145.1 0.0 2.6e-14 53.2 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX82820.1 - 6.9e-40 135.8 0.0 2.2e-13 50.9 0.0 4.6 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.15 KXX82820.1 - 1.3e-36 126.9 0.0 3e-36 125.7 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain HxxPF_rpt PF13745.1 KXX82820.1 - 3.2e-26 91.4 0.9 2.4e-17 63.0 0.1 4.5 5 0 0 5 5 5 2 HxxPF-repeated domain Abhydrolase_6 PF12697.2 KXX82820.1 - 4.7e-08 33.1 0.6 6e-07 29.5 0.0 3.1 4 0 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82820.1 - 0.00013 21.7 0.0 0.00095 18.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.13 KXX82821.1 - 3.6e-07 29.9 9.7 7e-07 29.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.12 KXX82822.1 - 3.2e-50 170.0 0.0 5.1e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III 2OG-FeII_Oxy PF03171.15 KXX82823.1 - 6.9e-21 74.4 0.0 3e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KXX82823.1 - 4.6e-12 46.4 0.0 7.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Lactamase_B_2 PF12706.2 KXX82824.1 - 2.3e-20 72.9 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KXX82824.1 - 3.6e-08 33.2 1.7 2.1e-07 30.8 1.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KXX82824.1 - 0.00018 21.1 4.7 0.0068 16.0 1.2 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily AMP-binding PF00501.23 KXX82825.1 - 2.5e-48 164.4 0.0 1.3e-24 86.3 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KXX82825.1 - 4e-10 40.5 0.0 8.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ldh_1_N PF00056.18 KXX82826.1 - 1.7e-44 151.0 0.0 3.8e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KXX82826.1 - 7.4e-43 146.2 0.0 1.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KXX82826.1 - 2.6e-05 23.0 0.0 3.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KXX82826.1 - 0.083 13.1 0.4 0.39 11.0 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.9 KXX82827.1 - 4.1e-44 150.9 0.0 7.3e-44 150.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.2 KXX82828.1 - 2.2e-29 101.6 0.0 8e-16 58.1 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82828.1 - 6.6e-24 82.4 0.9 0.00021 20.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KXX82828.1 - 6.1e-18 64.4 0.2 5.8e-05 23.2 0.1 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82828.1 - 7.2e-15 53.6 0.0 0.0059 16.7 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KXX82828.1 - 1.1e-13 51.2 0.5 4.1e-05 23.9 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) adh_short PF00106.20 KXX82829.1 - 4e-20 72.3 1.0 5.7e-20 71.8 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX82829.1 - 4.8e-18 65.8 0.0 5.8e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX82829.1 - 5.2e-07 29.5 0.6 7.2e-07 29.0 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KXX82829.1 - 0.00012 21.3 0.0 0.048 12.7 0.0 2.7 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) MARVEL PF01284.18 KXX82831.1 - 2.4e-22 79.3 16.2 2.9e-22 79.0 11.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain CsbD PF05532.7 KXX82832.1 - 4.9e-20 70.9 19.3 8.6e-12 44.5 1.1 3.1 2 1 1 3 3 3 3 CsbD-like BAR PF03114.13 KXX82833.1 - 1.1e-65 221.4 9.8 1.3e-65 221.1 6.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KXX82833.1 - 6.5e-15 54.2 0.0 1.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KXX82833.1 - 1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX82833.1 - 8.1e-10 38.0 0.3 3.6e-09 35.9 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain APG6 PF04111.7 KXX82833.1 - 0.8 8.6 10.2 1.9 7.4 4.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 KXX82833.1 - 6.3 5.7 8.0 0.48 9.4 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.14 KXX82834.1 - 2.6e-97 325.9 0.0 3.1e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KXX82834.1 - 3.8e-08 32.8 0.0 5.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KXX82834.1 - 7.7e-06 25.1 0.0 2e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KXX82834.1 - 0.0018 16.8 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KXX82834.1 - 0.063 11.5 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BOP1NT PF08145.7 KXX82835.1 - 3.2e-104 348.2 8.4 4.4e-104 347.8 5.8 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KXX82835.1 - 1.3e-26 91.4 0.1 4e-10 39.1 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 KXX82836.1 - 1.2e-17 64.6 4.6 1.8e-17 64.0 3.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KXX82836.1 - 1.9e-14 54.0 0.1 1.1e-13 51.5 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NAD_binding_8 PF13450.1 KXX82837.1 - 2.9e-10 40.0 0.0 9.4e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KXX82837.1 - 5.7e-09 35.5 0.1 7.2e-05 22.0 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KXX82837.1 - 7.6e-08 31.6 0.0 2.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX82837.1 - 0.00016 21.9 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX82837.1 - 0.12 12.2 0.2 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KXX82837.1 - 0.27 9.3 0.0 9.6 4.2 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) zf-CCCH_2 PF14608.1 KXX82838.1 - 3e-08 33.3 55.7 3.4e-06 26.8 8.0 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type RCR PF12273.3 KXX82838.1 - 1.4 9.4 11.9 3 8.4 8.3 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PAT1 PF09770.4 KXX82838.1 - 2.3 6.3 16.0 2.8 6.0 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_20 PF00728.17 KXX82839.1 - 1e-85 288.0 0.0 1.2e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KXX82839.1 - 7.7e-26 91.2 0.0 1.5e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KXX82839.1 - 1.1e-06 29.1 0.0 6.7e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PBP_like_2 PF12849.2 KXX82839.1 - 0.016 14.7 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain p450 PF00067.17 KXX82840.1 - 7e-54 183.0 0.0 1e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 KXX82841.1 - 1.8e-18 66.6 0.0 2.3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KXX82841.1 - 1.9e-06 26.7 0.0 2.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ATP-synt_8 PF00895.15 KXX82842.1 - 0.74 10.0 3.1 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 ATP synthase protein 8 DUF3792 PF12670.2 KXX82842.1 - 2 8.2 8.6 11 5.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Glyco_hydro_16 PF00722.16 KXX82843.1 - 1e-42 145.5 0.4 1.6e-42 144.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.10 KXX82844.1 - 2.3e-98 327.7 4.1 2.3e-98 327.7 2.8 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KXX82844.1 - 4.5e-84 281.2 6.1 4.5e-84 281.2 4.2 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KXX82844.1 - 1.3e-30 104.8 0.0 4.6e-30 103.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Med14 PF08638.6 KXX82845.1 - 4.9e-67 224.9 0.0 1e-66 223.9 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_C PF02781.11 KXX82846.1 - 1.3e-134 447.6 0.0 1.9e-134 447.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KXX82846.1 - 6.7e-64 215.4 0.0 1.1e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HET PF06985.6 KXX82848.1 - 1.7e-29 102.7 0.0 2.6e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VMA21 PF09446.5 KXX82849.1 - 1.1e-15 57.2 11.2 1.6e-15 56.7 7.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1118 PF06549.7 KXX82849.1 - 0.22 11.6 1.2 0.44 10.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) SNF2_N PF00176.18 KXX82850.1 - 3.6e-58 196.7 0.0 6.3e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KXX82850.1 - 1.6e-15 56.6 0.0 2e-14 53.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribosomal_L35Ae PF01247.13 KXX82851.1 - 1.9e-42 142.9 0.6 2.1e-42 142.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KXX82851.1 - 0.00042 20.1 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 KXX82852.1 - 6.2e-22 77.8 0.2 6.2e-22 77.8 0.1 2.7 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) DUF2217 PF10265.4 KXX82852.1 - 0.3 9.8 1.1 0.53 8.9 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3336 PF11815.3 KXX82853.1 - 4.2e-36 123.6 0.0 3.5e-35 120.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KXX82853.1 - 3.1e-14 53.3 1.0 5.9e-14 52.4 0.1 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase Amino_oxidase PF01593.19 KXX82855.1 - 2e-90 304.0 0.0 3.6e-90 303.2 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KXX82855.1 - 7.2e-10 38.8 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 KXX82855.1 - 1e-08 35.3 15.0 1.9e-08 34.4 5.7 2.9 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX82855.1 - 7e-08 32.7 6.6 7e-08 32.7 4.6 2.3 1 1 1 2 2 2 1 HMG-box domain NAD_binding_8 PF13450.1 KXX82855.1 - 9.6e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ATP-synt PF00231.14 KXX82856.1 - 9.3e-72 241.8 0.5 1.1e-71 241.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase FYVE PF01363.16 KXX82857.1 - 8.6e-22 76.8 1.9 8.6e-22 76.8 1.3 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KXX82857.1 - 6.7e-08 32.2 5.7 6.7e-08 32.2 3.9 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KXX82857.1 - 0.00072 19.1 2.6 0.00072 19.1 1.8 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 KXX82857.1 - 0.0031 16.9 2.1 0.036 13.5 0.3 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif FYVE_2 PF02318.11 KXX82857.1 - 0.0075 16.1 0.8 0.0075 16.1 0.6 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 KXX82857.1 - 0.019 14.9 4.8 0.019 14.9 3.3 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX82857.1 - 0.66 10.1 18.3 0.034 14.2 4.1 3.4 3 0 0 3 3 3 0 RING-H2 zinc finger zf-piccolo PF05715.8 KXX82857.1 - 1 9.4 9.1 2.1 8.4 3.3 2.8 2 0 0 2 2 2 0 Piccolo Zn-finger zf-DHHC PF01529.15 KXX82857.1 - 3.5 6.9 8.2 6.7 6.0 4.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase dCMP_cyt_deam_1 PF00383.17 KXX82858.1 - 8.6e-15 54.2 0.3 1.3e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KXX82858.1 - 1.3e-09 38.0 1.9 2.1e-08 34.1 0.2 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-SNAP50_C PF12251.3 KXX82858.1 - 0.041 13.2 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal ABC_membrane PF00664.18 KXX82859.1 - 6.7e-76 255.2 38.5 1.5e-38 132.8 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KXX82859.1 - 3.4e-62 208.7 4.3 1.3e-31 109.6 0.0 4.1 4 0 0 4 4 4 3 ABC transporter AAA_21 PF13304.1 KXX82859.1 - 1.1e-13 51.7 1.9 0.0018 18.3 0.0 3.9 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KXX82859.1 - 2.7e-09 36.5 10.9 0.002 17.4 2.6 4.5 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KXX82859.1 - 5.7e-09 35.3 0.5 0.0015 18.0 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KXX82859.1 - 1.1e-08 34.1 0.2 0.0058 15.2 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KXX82859.1 - 1.1e-07 31.1 0.1 0.0098 15.0 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KXX82859.1 - 6.1e-07 30.2 0.1 0.067 14.0 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX82859.1 - 1.4e-06 28.4 5.1 0.00063 19.7 0.2 3.6 3 1 0 3 3 3 2 AAA ATPase domain DUF3987 PF13148.1 KXX82859.1 - 7.7e-06 24.7 0.2 7.3e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_22 PF13401.1 KXX82859.1 - 2.5e-05 24.4 1.6 0.37 10.9 0.1 4.3 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.1 KXX82859.1 - 2.6e-05 23.4 2.6 0.0061 15.6 0.3 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 KXX82859.1 - 0.00016 21.3 1.2 1.8 8.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 KXX82859.1 - 0.00053 19.4 0.1 1.8 7.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KXX82859.1 - 0.00093 19.5 3.8 0.7 10.2 0.8 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KXX82859.1 - 0.0011 18.8 0.8 0.16 11.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KXX82859.1 - 0.0034 17.1 0.2 4.5 6.9 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KXX82859.1 - 0.0054 16.2 1.7 0.29 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 KXX82859.1 - 0.0094 15.9 0.8 4.7 7.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KXX82859.1 - 0.012 15.5 8.1 0.28 11.1 0.2 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KXX82859.1 - 0.017 14.8 0.5 6.5 6.4 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KXX82859.1 - 0.027 13.5 0.1 1.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 KXX82859.1 - 0.045 13.2 0.2 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KXX82859.1 - 0.049 13.9 14.2 0.86 9.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain BLVR PF06375.6 KXX82859.1 - 0.059 13.1 6.2 0.11 12.2 4.3 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Baculo_11_kDa PF06143.6 KXX82859.1 - 0.061 12.6 0.1 0.061 12.6 0.1 2.4 3 0 0 3 3 1 0 Baculovirus 11 kDa family MMR_HSR1 PF01926.18 KXX82859.1 - 0.074 13.0 0.1 17 5.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 KXX82859.1 - 0.093 12.2 0.1 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 KXX82859.1 - 0.18 12.2 2.2 14 6.1 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 KXX82859.1 - 0.52 10.0 4.1 1.4 8.7 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 tRNA-synt_His PF13393.1 KXX82860.1 - 3.9e-33 114.8 0.0 1.2e-26 93.5 0.0 2.5 2 1 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 KXX82860.1 - 1.2e-11 44.3 0.0 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 KXX82860.1 - 8.6e-10 38.4 0.0 3.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KXX82860.1 - 0.0082 14.9 0.0 0.37 9.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) DUF2681 PF10883.3 KXX82861.1 - 0.024 14.8 5.8 0.046 13.9 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TSA PF03249.8 KXX82861.1 - 0.027 13.0 4.9 0.042 12.3 3.4 1.2 1 0 0 1 1 1 0 Type specific antigen Pkinase PF00069.20 KXX82862.1 - 1.2e-71 240.9 0.0 1.6e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82862.1 - 2.1e-33 115.4 0.1 3.9e-33 114.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX82862.1 - 6.8e-05 21.9 0.0 9.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KXX82862.1 - 0.00032 20.1 0.1 0.00096 18.5 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KXX82862.1 - 0.0017 17.4 0.1 0.0033 16.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KXX82862.1 - 0.087 12.5 0.8 0.7 9.5 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-LITAF-like PF10601.4 KXX82862.1 - 0.11 12.4 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain UQ_con PF00179.21 KXX82863.1 - 9.1e-27 93.2 0.0 1.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX82863.1 - 4.2e-07 29.7 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX82863.1 - 0.00065 19.5 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KXX82863.1 - 0.009 15.6 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 UEV domain Sec1 PF00995.18 KXX82864.1 - 5.7e-141 470.9 0.0 6.4e-141 470.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UPF0167 PF03691.9 KXX82864.1 - 0.036 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) DUF4252 PF14060.1 KXX82864.1 - 0.096 12.2 0.3 3.4 7.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) TPK_B1_binding PF04265.9 KXX82865.1 - 1.2e-23 82.5 0.0 1.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 KXX82865.1 - 1.4e-15 56.9 0.0 1.2e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain DUF1279 PF06916.8 KXX82866.1 - 2.3e-29 101.5 0.0 3.5e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NinG PF05766.7 KXX82866.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein WD40 PF00400.27 KXX82867.1 - 5.6e-37 124.3 17.7 4.5e-13 48.5 0.6 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat NACHT PF05729.7 KXX82867.1 - 7.6e-24 84.2 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KXX82867.1 - 0.00043 18.5 0.7 3.1 5.8 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_19 PF13245.1 KXX82867.1 - 0.0086 15.8 0.0 0.036 13.8 0.0 2.1 1 1 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KXX82867.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Gemini_mov PF01708.11 KXX82868.1 - 0.059 12.9 1.4 0.11 12.0 1.0 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein AA_permease_2 PF13520.1 KXX82869.1 - 4.8e-78 262.5 30.3 5.8e-78 262.3 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KXX82869.1 - 8e-19 67.3 27.3 2.2e-18 65.8 18.9 1.6 1 1 0 1 1 1 1 Amino acid permease V-SNARE_C PF12352.3 KXX82870.1 - 2.1e-14 53.3 0.5 2.1e-14 53.3 0.4 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KXX82870.1 - 6.6e-05 22.5 0.0 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 KXX82870.1 - 0.0079 15.4 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.7 KXX82870.1 - 0.066 12.7 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Allexi_40kDa PF05549.6 KXX82870.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.7 KXX82870.1 - 0.2 11.3 2.4 1.3 8.7 0.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 KXX82870.1 - 0.2 11.1 2.6 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.2 KXX82870.1 - 0.24 10.6 10.5 0.029 13.6 3.9 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain KxDL PF10241.4 KXX82870.1 - 1.7 8.6 4.3 9.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein FliD_N PF02465.13 KXX82870.1 - 5.2 7.4 7.1 3.3 8.1 0.3 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Hydrolase PF00702.21 KXX82871.1 - 1.4e-22 81.1 0.0 9.1e-22 78.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KXX82871.1 - 3.9e-21 75.1 0.0 1e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KXX82871.1 - 4.3e-19 69.4 0.0 9.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KXX82871.1 - 0.00016 21.5 1.4 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KXX82871.1 - 0.0016 18.0 1.2 0.03 13.9 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KXX82871.1 - 0.019 14.2 0.4 1.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase OmpH PF03938.9 KXX82871.1 - 0.75 9.7 10.1 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Atrophin-1 PF03154.10 KXX82871.1 - 3.8 5.5 20.1 0.018 13.2 7.6 1.6 2 0 0 2 2 2 0 Atrophin-1 family Whi5 PF08528.6 KXX82873.1 - 1.3e-09 37.3 0.0 2.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Whi5 like Aldo_ket_red PF00248.16 KXX82875.1 - 3.2e-58 196.7 0.0 3.7e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NMO PF03060.10 KXX82877.1 - 6.4e-38 130.7 5.4 3.7e-30 105.2 1.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KXX82877.1 - 1.4e-09 37.3 0.0 0.0021 17.0 2.2 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KXX82877.1 - 2.9e-05 23.0 3.3 5.2e-05 22.2 2.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase UCH PF00443.24 KXX82878.1 - 1.4e-51 175.2 1.5 2.3e-50 171.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX82878.1 - 5.8e-21 75.2 1.8 9e-21 74.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GvpL_GvpF PF06386.6 KXX82878.1 - 0.52 9.8 11.0 1.4 8.3 7.6 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Sec61_beta PF03911.11 KXX82879.1 - 7.6e-21 73.6 1.5 9.8e-21 73.2 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.7 KXX82879.1 - 0.055 13.3 1.6 0.067 13.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.13 KXX82880.1 - 8.8e-51 171.7 0.2 1.2e-50 171.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 KXX82881.1 - 1.8e-97 325.9 3.1 6.6e-97 324.0 0.1 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KXX82881.1 - 5.5e-16 59.1 0.1 2.1e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KXX82881.1 - 0.0051 16.8 0.0 0.043 13.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KXX82881.1 - 0.015 16.1 4.0 0.18 12.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KXX82881.1 - 0.019 14.0 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KXX82881.1 - 0.02 14.8 0.0 0.071 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KXX82881.1 - 0.032 13.7 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KXX82881.1 - 0.08 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KXX82881.1 - 0.091 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 KXX82881.1 - 2.1 7.5 3.8 10 5.2 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Abhydrolase_5 PF12695.2 KXX82882.1 - 1.1e-14 54.4 0.1 2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82882.1 - 9.6e-14 51.8 2.5 2.5e-13 50.4 1.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX82882.1 - 9.1e-09 35.1 0.4 1.5e-08 34.4 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KXX82882.1 - 0.00033 20.2 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX82882.1 - 0.008 15.4 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF218 PF02698.12 KXX82882.1 - 0.02 14.4 0.0 0.073 12.5 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain Abhydrolase_2 PF02230.11 KXX82882.1 - 0.036 13.5 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KXX82882.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 KXX82882.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Glyco_trans_4_4 PF13579.1 KXX82882.1 - 0.62 10.1 4.1 1.9 8.6 0.6 2.8 1 1 2 3 3 3 0 Glycosyl transferase 4-like domain Pkinase PF00069.20 KXX82883.1 - 1.5e-60 204.5 0.1 1.8e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82883.1 - 4.5e-20 71.8 0.0 6.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX82883.1 - 1.6e-08 34.5 0.0 8e-06 25.7 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX82883.1 - 0.01 15.4 0.1 0.024 14.2 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KXX82883.1 - 0.062 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KXX82883.1 - 0.074 12.1 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KXX82883.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PP2C PF00481.16 KXX82884.1 - 1.2e-56 191.9 0.0 2.5e-56 190.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KXX82884.1 - 2.2e-47 158.0 62.3 1.4e-06 27.7 0.2 12.7 4 4 9 14 14 14 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX82884.1 - 4.4e-40 135.2 54.8 5e-09 35.7 0.4 10.1 5 3 5 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 KXX82884.1 - 3e-27 95.1 0.0 5.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KXX82884.1 - 2.9e-23 78.2 58.6 0.29 11.2 0.0 19.8 18 2 1 19 19 19 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 KXX82884.1 - 2.3e-20 71.6 2.8 7e-20 70.1 1.9 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 KXX82884.1 - 7.3e-12 43.4 50.9 0.59 10.5 0.1 17.1 18 1 0 18 18 18 3 Leucine rich repeat RA PF00788.18 KXX82884.1 - 3.5e-10 40.2 0.1 2e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 KXX82884.1 - 1.4e-05 24.6 47.6 8.2 6.8 0.1 15.6 18 1 0 18 18 18 1 Leucine Rich repeat Baculo_PEP_N PF04512.7 KXX82884.1 - 0.029 14.3 1.2 71 3.4 0.0 4.8 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, N terminus Yos1 PF08571.5 KXX82885.1 - 8.5e-28 96.2 0.3 9.4e-28 96.1 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Aldo_ket_red PF00248.16 KXX82886.1 - 3.6e-49 167.1 0.0 4.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 KXX82887.1 - 1.1e-40 136.6 27.1 8.6e-11 41.2 0.3 7.0 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX82887.1 - 7.8e-32 108.8 63.1 6.7e-08 32.1 0.4 4.8 1 1 7 8 8 8 8 Leucine rich repeat LRR_6 PF13516.1 KXX82887.1 - 6.3e-12 44.2 21.5 0.3 11.2 0.1 10.4 6 4 5 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.1 KXX82887.1 - 2.2e-11 43.6 9.9 6e-05 22.6 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 KXX82887.1 - 3.3e-10 38.4 18.6 1.1 9.7 0.0 9.0 9 0 0 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 KXX82887.1 - 1e-09 37.0 27.1 0.12 12.4 0.2 10.1 11 0 0 11 11 11 4 Leucine Rich Repeat FAD_binding_4 PF01565.18 KXX82888.1 - 2.6e-26 91.7 1.6 7.5e-26 90.2 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KXX82888.1 - 2.2e-06 27.4 0.4 4.5e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KXX82889.1 - 1.3e-31 109.6 0.0 2.9e-21 75.5 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 KXX82890.1 - 7.9e-20 71.4 1.5 1.6e-19 70.4 1.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82890.1 - 9.9e-09 35.1 0.3 1.3e-08 34.7 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX82890.1 - 2.8e-08 33.8 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KXX82890.1 - 7.7e-07 28.7 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KXX82890.1 - 8.3e-06 25.9 0.3 0.00043 20.3 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KXX82890.1 - 0.013 14.3 0.1 0.03 13.2 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein Eno-Rase_NADH_b PF12242.3 KXX82890.1 - 0.091 12.5 0.2 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KXX82891.1 - 1.4e-07 30.6 0.1 2.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KXX82892.1 - 2e-54 184.8 0.0 1.1e-53 182.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 KXX82893.1 - 8.5e-05 21.9 0.0 9.8e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease NIF PF03031.13 KXX82895.1 - 5.3e-37 126.9 0.0 7.7e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Transposase_22 PF02994.9 KXX82895.1 - 0.051 12.0 0.7 0.099 11.1 0.5 1.4 1 0 0 1 1 1 0 L1 transposable element Metallophos PF00149.23 KXX82896.1 - 1.1e-08 34.6 2.7 4.7e-08 32.6 1.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KXX82897.1 - 2e-13 49.8 0.3 4e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82897.1 - 8.5e-08 31.9 7.5 1.8e-07 30.9 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.5 KXX82898.1 - 1.8e-45 154.5 0.0 2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Zeta_toxin PF06414.7 KXX82898.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Pro_dh PF01619.13 KXX82899.1 - 2.5e-40 138.4 0.0 3.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DUF3176 PF11374.3 KXX82901.1 - 3.2e-33 113.9 0.0 6.4e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short PF00106.20 KXX82902.1 - 1.5e-19 70.5 0.6 4.5e-19 68.9 0.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX82902.1 - 5.5e-08 32.6 0.2 2.4e-07 30.6 0.2 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX82902.1 - 0.0015 17.9 0.3 0.0039 16.6 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KXX82902.1 - 0.0042 17.4 0.1 0.0093 16.3 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 KXX82902.1 - 0.0046 16.7 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KXX82902.1 - 0.0082 15.1 0.1 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KXX82902.1 - 0.017 15.1 0.2 0.045 13.7 0.2 1.8 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KXX82902.1 - 0.018 14.2 0.1 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 KXX82902.1 - 0.04 13.1 0.1 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.15 KXX82902.1 - 0.051 13.6 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_2 PF00891.13 KXX82903.1 - 5.1e-31 107.7 0.0 6.8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KXX82903.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX82903.1 - 0.00031 20.1 0.0 0.00073 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KXX82903.1 - 0.00038 21.0 0.0 0.00088 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX82903.1 - 0.0043 17.3 0.0 0.056 13.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82903.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KXX82903.1 - 0.032 13.2 0.0 0.063 12.3 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 KXX82903.1 - 0.074 12.7 0.0 0.52 10.0 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82903.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PS-DH PF14765.1 KXX82904.1 - 9e-70 235.1 0.1 1.8e-69 234.1 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 KXX82904.1 - 2.9e-69 233.3 0.1 6.6e-69 232.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KXX82904.1 - 2.2e-54 184.9 0.2 4.3e-54 183.9 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KXX82904.1 - 2.9e-49 167.1 2.6 3.2e-49 167.0 0.2 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KXX82904.1 - 6e-42 143.3 0.2 6e-42 143.3 0.1 2.8 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX82904.1 - 2.5e-35 120.8 1.2 4.4e-35 120.1 0.1 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KXX82904.1 - 1.8e-19 70.0 0.0 4.6e-18 65.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX82904.1 - 5.3e-14 52.2 0.0 3.4e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82904.1 - 3.9e-11 43.2 0.0 7.4e-10 39.1 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82904.1 - 4.9e-10 39.1 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82904.1 - 1.3e-09 38.5 0.0 2e-08 34.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 KXX82904.1 - 3.6e-07 29.7 0.0 4.6e-05 22.9 0.0 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX82904.1 - 2e-06 27.9 0.4 6.4e-06 26.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 KXX82904.1 - 3.7e-06 26.0 0.0 5.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 KXX82904.1 - 7.3e-06 26.2 0.0 0.00024 21.3 0.0 3.6 4 0 0 4 4 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82904.1 - 8.3e-06 25.0 0.0 1.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KXX82904.1 - 0.00052 19.0 0.1 0.0013 17.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain MTS PF05175.9 KXX82904.1 - 0.0011 18.4 0.0 0.011 15.1 0.0 2.7 4 0 0 4 4 2 1 Methyltransferase small domain ACP_syn_III PF08545.5 KXX82904.1 - 0.0024 17.4 0.3 0.0067 16.0 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 KXX82904.1 - 0.0028 17.4 0.2 0.0058 16.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 KXX82904.1 - 0.0033 16.1 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 KXX82904.1 - 0.0033 17.4 0.1 0.02 14.9 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain DNA_gyraseB_C PF00986.16 KXX82904.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus NodS PF05401.6 KXX82904.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 KXX82904.1 - 0.99 8.9 0.0 2 8.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_23 PF13489.1 KXX82905.1 - 1.4e-09 37.8 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82905.1 - 8.8e-08 32.5 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82905.1 - 5.7e-05 23.6 0.0 0.0023 18.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX82905.1 - 0.00019 21.0 0.0 0.0011 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82905.1 - 0.0069 16.8 0.0 0.036 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KXX82905.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MFS_1 PF07690.11 KXX82906.1 - 1.7e-38 132.2 47.9 1.2e-36 126.2 33.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KXX82906.1 - 5.6e-14 51.2 17.5 1.7e-13 49.6 12.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RhoGAP PF00620.22 KXX82908.1 - 1e-15 57.6 0.0 2.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Methyltransf_31 PF13847.1 KXX82909.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX82909.1 - 7e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX82909.1 - 8.5e-05 22.9 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX82909.1 - 0.0002 21.1 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX82909.1 - 0.00081 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX82909.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KXX82909.1 - 0.023 15.0 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PTS_2-RNA PF01885.11 KXX82910.1 - 9.6e-14 51.1 0.0 2.3e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KXX82910.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 La domain 6PGD PF00393.14 KXX82911.1 - 1.6e-69 234.3 0.0 2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KXX82911.1 - 2.1e-29 102.4 0.1 5e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KXX82911.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KXX82911.1 - 0.002 17.8 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 KXX82911.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.11 KXX82911.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AP_endonuc_2 PF01261.19 KXX82912.1 - 3.9e-33 114.5 0.0 6.2e-33 113.8 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 KXX82912.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus HET PF06985.6 KXX82913.1 - 6.9e-29 100.7 0.0 2.3e-28 99.0 0.0 1.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ricin_B_lectin PF00652.17 KXX82914.1 - 1.3e-11 44.5 1.4 1.4e-08 34.7 0.4 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KXX82914.1 - 2.3e-09 37.5 3.0 1.2e-05 25.6 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF884 PF05959.6 KXX82914.1 - 0.03 13.6 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF884) WD40 PF00400.27 KXX82916.1 - 2.3e-19 68.4 8.4 2.5e-07 30.3 0.0 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat MRP-L46 PF11788.3 KXX82916.1 - 2.5 8.7 6.6 0.39 11.3 1.3 2.0 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 ATP-synt_E PF05680.7 KXX82917.1 - 1.7e-24 85.5 0.9 1.8e-24 85.5 0.6 1.1 1 0 0 1 1 1 1 ATP synthase E chain Gag_p17 PF00540.13 KXX82917.1 - 0.12 12.0 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) tRNA-synt_1d PF00750.14 KXX82919.1 - 1.1e-72 244.8 0.2 2.1e-72 243.8 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) Acetyltransf_3 PF13302.1 KXX82919.1 - 1e-36 126.1 0.0 2.8e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DALR_1 PF05746.10 KXX82919.1 - 3.1e-13 49.7 0.1 6e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arf PF00025.16 KXX82919.1 - 1.6e-12 46.9 0.0 7.2e-11 41.6 0.0 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Acetyltransf_4 PF13420.1 KXX82919.1 - 0.0014 18.6 0.0 0.069 13.1 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KXX82919.1 - 0.021 14.8 0.2 0.85 9.6 0.1 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KXX82919.1 - 0.043 13.6 0.0 0.9 9.4 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 KXX82920.1 - 8.5e-10 38.3 5.7 1.4e-09 37.7 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX82920.1 - 5.1e-06 25.5 0.2 1.5e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1656 PF07869.7 KXX82921.1 - 0.28 11.0 2.6 0.47 10.2 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Tom22 PF04281.8 KXX82921.1 - 0.69 9.4 2.9 1.2 8.6 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Ribosomal_60s PF00428.14 KXX82921.1 - 1.7 9.1 6.1 1.6 9.1 2.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 KXX82921.1 - 3.3 8.0 8.0 6.8 6.9 4.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BTB PF00651.26 KXX82922.1 - 4.5e-11 42.7 0.2 2.3e-10 40.4 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 KXX82922.1 - 0.001 19.1 0.0 0.0063 16.5 0.0 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Abhydrolase_5 PF12695.2 KXX82923.1 - 1.6e-07 31.1 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82923.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 2.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family DMRL_synthase PF00885.14 KXX82923.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Ribosomal_L18ae PF01775.12 KXX82924.1 - 7.9e-59 196.9 0.5 9.8e-59 196.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 KXX82925.1 - 3.9e-12 46.4 0.0 1.1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 KXX82925.1 - 0.0017 17.9 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 TPR repeat Cbl_N PF02262.11 KXX82925.1 - 0.01 15.5 0.2 0.046 13.4 0.0 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Glyco_hydro_45 PF02015.11 KXX82926.1 - 1.1e-89 299.8 20.4 1.3e-89 299.6 14.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Het-C PF07217.6 KXX82927.1 - 9e-261 866.3 0.0 1.1e-260 866.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Maf PF02545.9 KXX82928.1 - 9.9e-43 145.5 0.0 1.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Glyco_hydro_47 PF01532.15 KXX82929.1 - 1.3e-164 548.1 0.0 1.5e-164 547.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3791 PF12668.2 KXX82929.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Utp11 PF03998.8 KXX82930.1 - 2.7e-58 197.6 23.2 3.2e-58 197.4 16.1 1.0 1 0 0 1 1 1 1 Utp11 protein OmpH PF03938.9 KXX82930.1 - 0.23 11.3 15.9 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4337 PF14235.1 KXX82930.1 - 1.5 8.6 19.2 3.9 7.2 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Bd3614_N PF14442.1 KXX82930.1 - 2.8 7.9 8.2 0.19 11.7 1.6 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase N-terminal Plug_translocon PF10559.4 KXX82931.1 - 0.021 14.3 0.1 0.045 13.2 0.1 1.5 1 0 0 1 1 1 0 Plug domain of Sec61p HMG_box PF00505.14 KXX82932.1 - 3.1e-07 30.5 0.1 9.3e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX82932.1 - 0.00011 22.4 0.6 0.00076 19.7 0.0 2.5 2 0 0 2 2 2 1 HMG-box domain tRNA-synt_2b PF00587.20 KXX82933.1 - 1.2e-47 161.7 0.0 1.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KXX82933.1 - 3e-07 30.2 0.0 5.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF848 PF05852.6 KXX82934.1 - 0.076 12.8 0.2 0.4 10.5 0.0 2.1 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Amidohydro_1 PF01979.15 KXX82935.1 - 1.7e-60 205.4 1.7 2.3e-60 204.9 1.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KXX82935.1 - 3.1e-55 185.4 2.7 1.2e-54 183.6 0.6 2.3 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KXX82935.1 - 1.7e-41 140.1 0.6 4.9e-41 138.6 0.1 2.1 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KXX82935.1 - 2e-35 120.7 0.0 4.7e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KXX82935.1 - 4.9e-07 29.4 4.2 1.4e-06 28.0 2.9 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KXX82935.1 - 1.3e-06 27.9 0.6 0.00011 21.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 KXX82935.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase PLA2_B PF01735.13 KXX82937.1 - 9.3e-192 637.5 0.0 1.1e-191 637.3 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TFIID-31kDa PF02291.10 KXX82939.1 - 6.9e-18 64.6 0.0 9.7e-12 44.7 0.0 2.9 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Histidinol_dh PF00815.15 KXX82940.1 - 1.2e-179 597.2 5.1 1.6e-179 596.9 3.5 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KXX82940.1 - 2.4e-24 84.7 0.1 5e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KXX82940.1 - 1.7e-09 37.7 0.8 8e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Phasin_2 PF09361.5 KXX82940.1 - 0.042 13.8 3.3 0.39 10.7 0.7 3.3 4 0 0 4 4 4 0 Phasin protein fn3 PF00041.16 KXX82941.1 - 1.5e-07 31.4 0.0 4.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Metal_resist PF13801.1 KXX82941.1 - 0.024 14.6 0.4 0.024 14.6 0.3 3.9 2 2 1 3 3 3 0 Heavy-metal resistance RabGAP-TBC PF00566.13 KXX82941.1 - 4.5 6.6 4.6 9.7 5.5 3.2 1.5 1 0 0 1 1 1 0 Rab-GTPase-TBC domain LNS2 PF08235.8 KXX82942.1 - 1.8e-71 238.7 0.0 3.2e-71 238.0 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KXX82942.1 - 1.2e-39 134.3 0.0 6.2e-39 132.0 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KXX82942.1 - 0.002 17.5 0.0 0.16 11.3 0.0 2.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 KXX82942.1 - 2.2 8.2 10.6 0.053 13.4 0.4 2.5 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator DAO PF01266.19 KXX82943.1 - 1.8e-16 59.9 0.4 1.1e-15 57.4 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KXX82943.1 - 6.5e-06 26.4 0.1 1.4e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX82943.1 - 0.00025 21.0 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX82943.1 - 0.0003 20.7 0.6 0.0008 19.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KXX82943.1 - 0.00038 19.4 0.7 0.00056 18.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KXX82943.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KXX82943.1 - 0.0012 17.9 0.7 0.0018 17.3 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KXX82943.1 - 0.0014 18.2 0.2 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KXX82943.1 - 0.015 14.8 0.4 0.023 14.2 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KXX82943.1 - 0.032 13.0 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KXX82943.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KXX82943.1 - 0.056 12.8 1.4 0.091 12.1 1.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KXX82943.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 KXX82943.1 - 0.067 11.6 1.6 0.096 11.1 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KXX82943.1 - 0.14 12.2 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX82943.1 - 0.15 11.1 0.2 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Cmc1 PF08583.5 KXX82944.1 - 1.6e-18 66.1 3.1 1.6e-18 66.1 2.2 1.8 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KXX82944.1 - 0.00051 19.8 1.9 0.75 9.7 0.1 2.4 2 0 0 2 2 2 2 CHCH domain DUF501 PF04417.7 KXX82944.1 - 0.19 11.5 2.0 0.35 10.7 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Atrophin-1 PF03154.10 KXX82944.1 - 0.31 9.1 13.4 0.38 8.8 9.1 1.3 1 1 0 1 1 1 0 Atrophin-1 family Phage-scaffold PF09306.5 KXX82944.1 - 2.9 6.9 6.5 3.8 6.5 4.2 1.4 1 1 0 1 1 1 0 Bacteriophage, scaffolding protein SnoaL PF07366.7 KXX82946.1 - 4.8e-14 52.0 0.2 3.3e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KXX82946.1 - 1.6e-07 31.6 0.2 3.3e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain HET PF06985.6 KXX82947.1 - 1.5e-28 99.6 0.0 3.2e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 KXX82948.1 - 1.7e-98 317.9 10.0 3.9e-09 35.8 0.0 13.9 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.2 KXX82948.1 - 1.4e-87 288.0 7.6 2.9e-18 65.9 0.0 7.7 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX82948.1 - 4.8e-70 224.4 6.2 1.4e-05 24.8 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KXX82948.1 - 1.5e-68 226.0 7.4 1.3e-09 38.2 0.1 8.7 5 3 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX82948.1 - 3.9e-65 214.3 19.0 8.4e-09 35.3 0.0 12.1 2 2 10 12 12 12 11 Ankyrin repeats (many copies) Peptidase_S8 PF00082.17 KXX82948.1 - 1.3e-16 60.5 0.1 2.7e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family 3-dmu-9_3-mt PF06983.8 KXX82949.1 - 1.9e-48 163.5 0.3 2.5e-48 163.2 0.2 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase FAD_binding_4 PF01565.18 KXX82951.1 - 1.3e-27 95.9 0.4 2.2e-27 95.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX82951.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like TMEM151 PF14857.1 KXX82951.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family Tyrosinase PF00264.15 KXX82952.1 - 1.1e-37 130.4 0.0 1.6e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_C1 PF00112.18 KXX82953.1 - 7.1e-27 94.7 1.0 1.3e-26 93.9 0.7 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Flavin_Reduct PF01613.13 KXX82954.1 - 4e-21 75.4 0.0 5.7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain TPP_enzyme_N PF02776.13 KXX82957.1 - 1.4e-34 119.0 6.4 4.3e-33 114.2 0.2 2.7 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KXX82957.1 - 1.8e-17 63.3 0.3 6.6e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KXX82957.1 - 2.3e-14 53.3 0.1 8.9e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain AhpC-TSA PF00578.16 KXX82958.1 - 4.9e-08 32.6 0.0 9.1e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KXX82958.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KXX82958.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Pkinase PF00069.20 KXX82959.1 - 1e-46 159.1 0.0 1.2e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82959.1 - 1.1e-25 90.2 0.0 1.4e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX82959.1 - 2.9e-08 33.0 0.0 3.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Homeobox_KN PF05920.6 KXX82959.1 - 0.024 14.3 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 0 Homeobox KN domain APH PF01636.18 KXX82959.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KXX82959.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KXX82959.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KXX82960.1 - 2.3e-07 30.2 0.0 4.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX82960.1 - 2.3e-06 26.8 0.1 9.7e-06 24.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1363 PF07101.6 KXX82962.1 - 0.0018 18.3 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1363) MFS_1 PF07690.11 KXX82963.1 - 9.6e-29 100.1 37.9 1.2e-28 99.8 26.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2631 PF10939.3 KXX82963.1 - 0.53 10.1 0.1 0.53 10.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) p450 PF00067.17 KXX82964.1 - 1.8e-59 201.5 0.0 2.5e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELMO_CED12 PF04727.8 KXX82964.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 ELMO/CED-12 family Trypsin_2 PF13365.1 KXX82967.1 - 3.1e-17 62.6 0.0 4.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 KXX82967.1 - 0.00035 19.5 0.0 0.0014 17.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C4 Peptidase_S46 PF10459.4 KXX82967.1 - 0.034 12.5 0.0 0.39 9.0 0.1 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.8 KXX82967.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 CorA PF01544.13 KXX82968.1 - 5.8e-24 84.6 8.6 1.9e-20 73.1 3.3 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Zn_clus PF00172.13 KXX82969.1 - 8.2e-08 32.0 9.7 1.7e-07 31.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD PF09423.5 KXX82971.1 - 3e-148 494.1 4.2 3.7e-148 493.8 2.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase MFS_1 PF07690.11 KXX82972.1 - 3.1e-28 98.5 22.1 4e-28 98.1 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KXX82972.1 - 3e-14 52.4 10.4 5.3e-14 51.6 7.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KXX82972.1 - 2.4e-09 35.9 4.4 3.7e-09 35.3 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KXX82973.1 - 6e-38 130.4 29.9 1.4e-37 129.2 20.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KXX82973.1 - 0.053 13.9 0.6 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Orbi_NS3 PF01616.11 KXX82974.1 - 0.074 12.0 1.1 0.18 10.7 0.1 2.0 2 0 0 2 2 2 0 Orbivirus NS3 ASFV_J13L PF05568.6 KXX82974.1 - 0.2 11.1 0.7 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein ABC2_membrane_5 PF13346.1 KXX82974.1 - 3.1 7.0 12.8 1.5 8.0 1.2 2.7 2 1 0 3 3 3 0 ABC-2 family transporter protein Nup_retrotrp_bd PF10599.4 KXX82975.1 - 0.029 15.0 1.0 0.044 14.4 0.6 1.4 1 1 0 1 1 1 0 Retro-transposon transporting motif Abhydrolase_6 PF12697.2 KXX82976.1 - 0.002 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX82976.1 - 0.0071 16.0 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX82976.1 - 0.028 13.7 0.0 0.1 11.8 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2855 PF11017.3 KXX82977.1 - 2e-44 152.0 0.0 2.4e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) HET PF06985.6 KXX82978.1 - 3.1e-19 69.5 9.0 6.6e-17 61.9 1.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 KXX82979.1 - 5.3e-07 29.7 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KXX82979.1 - 1.7e-06 27.5 0.0 2.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KXX82979.1 - 5.9e-05 22.8 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KXX82979.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.8 KXX82979.1 - 0.00021 20.9 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF829 PF05705.9 KXX82979.1 - 0.00091 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Lipase_3 PF01764.20 KXX82979.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KXX82979.1 - 0.019 14.5 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF726 PF05277.7 KXX82979.1 - 0.058 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Pet20 PF08692.5 KXX82980.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Sp38 PF07354.7 KXX82980.1 - 0.077 11.6 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) HPP PF04982.8 KXX82981.1 - 3.5e-22 78.4 5.8 3.5e-22 78.4 4.0 1.7 1 1 1 2 2 2 1 HPP family RskA PF10099.4 KXX82981.1 - 0.32 10.7 4.3 0.33 10.6 2.0 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2755 PF10954.3 KXX82981.1 - 3.5 7.3 5.4 1.2 8.9 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2755) FAD_binding_4 PF01565.18 KXX82982.1 - 3.1e-18 65.5 1.1 6.6e-18 64.5 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX82982.1 - 1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aminotran_5 PF00266.14 KXX82983.1 - 1.8e-08 33.5 0.0 2.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KXX82983.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KXX82983.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 KXX82984.1 - 1.2e-143 478.5 0.0 1.6e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase WD40 PF00400.27 KXX82985.1 - 2.1e-20 71.7 10.7 2.8e-08 33.3 0.2 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KXX82985.1 - 8.9e-18 63.9 0.0 2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex O-FucT PF10250.4 KXX82986.1 - 5.9e-14 51.9 0.1 2.1e-11 43.5 0.1 3.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3445 PF11927.3 KXX82987.1 - 8e-46 156.4 0.0 3.8e-45 154.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) DUF2286 PF10051.4 KXX82987.1 - 0.061 12.9 0.5 0.1 12.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) HET PF06985.6 KXX82988.1 - 1.4e-20 73.8 0.1 3.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 KXX82989.1 - 6.9e-08 31.9 0.3 0.0024 17.0 0.0 2.5 2 1 0 2 2 2 2 Subtilase family FAD_binding_4 PF01565.18 KXX82991.1 - 2.1e-27 95.2 2.7 2.1e-27 95.2 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KXX82991.1 - 5.8e-06 26.1 0.2 1.3e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like AAA_12 PF13087.1 KXX82993.1 - 1.6e-28 99.4 0.0 4.5e-28 98.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KXX82993.1 - 5.4e-19 68.7 0.0 1.7e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KXX82993.1 - 1.3e-11 44.0 0.1 5.2e-09 35.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KXX82993.1 - 4.2e-06 26.4 0.0 2.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KXX82993.1 - 0.00034 20.0 0.0 0.00071 18.9 0.0 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KXX82993.1 - 0.0017 18.0 0.1 0.038 13.6 0.0 2.7 2 1 0 2 2 2 1 Helicase ResIII PF04851.10 KXX82993.1 - 0.0027 17.5 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KXX82993.1 - 0.0031 16.5 0.0 0.059 12.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KXX82993.1 - 0.0031 17.6 0.0 0.015 15.4 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 KXX82993.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KXX82993.1 - 0.032 13.6 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KXX82993.1 - 0.036 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.13 KXX82993.1 - 0.057 12.9 0.0 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase U79_P34 PF03064.11 KXX82994.1 - 0.48 9.9 31.3 1.7 8.0 21.7 1.8 1 1 0 1 1 1 0 HSV U79 / HCMV P34 DUF1524 PF07510.6 KXX82995.1 - 1.1e-12 47.9 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) PGAP1 PF07819.8 KXX82996.1 - 4.6e-05 23.1 0.0 9.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 KXX82996.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 KXX82996.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX82996.1 - 0.0066 16.3 0.1 0.017 14.9 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 KXX82996.1 - 0.051 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ank_2 PF12796.2 KXX82997.1 - 1.8e-71 236.4 2.0 8.6e-12 45.2 0.0 10.2 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KXX82997.1 - 5.6e-63 205.7 4.7 9.7e-06 25.1 0.0 14.7 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.1 KXX82997.1 - 2.5e-57 189.5 4.9 5e-05 23.4 0.0 13.9 9 3 4 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX82997.1 - 2.8e-53 177.3 6.4 1.6e-07 31.6 0.0 13.3 9 4 5 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX82997.1 - 5.3e-49 159.3 1.4 0.00099 19.1 0.0 15.5 16 0 0 16 16 16 14 Ankyrin repeat Fungal_trans PF04082.13 KXX82999.1 - 7.6e-12 44.6 0.0 1.7e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX82999.1 - 9.7e-05 22.2 8.1 9.7e-05 22.2 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lenti_VIF_2 PF07401.7 KXX82999.1 - 0.029 13.4 0.2 0.18 10.9 0.0 2.2 3 0 0 3 3 3 0 Bovine Lentivirus VIF protein Kelch_4 PF13418.1 KXX83000.1 - 2.8e-13 49.3 15.8 0.0046 16.6 0.2 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KXX83000.1 - 6.5e-12 45.0 17.6 0.00095 19.2 0.1 5.7 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KXX83000.1 - 1.6e-10 40.7 8.8 0.0036 17.2 0.1 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KXX83000.1 - 1.1e-07 31.2 14.3 0.19 11.2 0.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 KXX83000.1 - 4.6e-06 26.6 13.0 0.093 12.9 0.2 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KXX83000.1 - 4e-05 23.1 3.4 0.54 10.1 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Herpes_gE PF02480.11 KXX83000.1 - 0.1 10.8 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E p450 PF00067.17 KXX83001.1 - 2.1e-63 214.4 0.0 5.7e-62 209.7 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 SnoaL_2 PF12680.2 KXX83002.1 - 2.8e-05 24.4 0.0 4.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KXX83002.1 - 0.052 13.6 0.2 0.67 10.0 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like domain RdRP PF05183.7 KXX83003.1 - 1.9e-77 261.3 0.0 2.4e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EAL PF00563.15 KXX83003.1 - 0.035 13.6 0.2 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 EAL domain RdRP PF05183.7 KXX83004.1 - 1.5e-40 139.4 0.1 2.9e-40 138.5 0.1 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 KXX83004.1 - 0.0052 16.7 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KXX83004.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ILVD_EDD PF00920.16 KXX83005.1 - 4e-194 645.8 2.9 4.6e-194 645.6 2.0 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 KXX83005.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Glyco_transf_15 PF01793.11 KXX83006.1 - 4.1e-132 440.1 0.3 5.2e-132 439.7 0.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PadR PF03551.9 KXX83006.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Myb_DNA-binding PF00249.26 KXX83007.1 - 3.8e-13 49.2 2.0 8.2e-07 28.9 0.4 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX83007.1 - 5e-11 42.5 0.9 2e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX83008.1 - 0.0011 19.0 0.3 0.003 17.6 0.2 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KXX83008.1 - 0.023 14.7 0.3 0.25 11.4 0.4 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.16 KXX83010.1 - 7.9e-44 149.1 2.2 1.4e-43 148.3 1.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Herpes_capsid PF06112.6 KXX83010.1 - 5.3 7.0 7.1 8.8 6.3 4.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PhzC-PhzF PF02567.11 KXX83011.1 - 2.2e-43 148.4 0.0 3.1e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein zf-RING_5 PF14634.1 KXX83013.1 - 0.0016 18.1 3.3 0.0048 16.5 2.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KXX83013.1 - 0.0096 15.9 0.9 0.0096 15.9 0.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KXX83013.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KXX83013.1 - 0.11 12.3 1.2 1 9.3 0.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 KXX83013.1 - 0.19 11.5 2.9 0.23 11.2 0.9 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.1 KXX83013.1 - 0.28 11.0 3.0 0.33 10.8 0.8 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 KXX83013.1 - 1.6 8.4 6.2 4.2 7.1 4.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.6 KXX83014.1 - 6.5e-31 105.8 1.5 6.5e-31 105.8 1.0 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 KXX83014.1 - 1e-11 44.2 5.5 0.00044 20.0 0.0 6.1 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.6 KXX83014.1 - 1.2e-05 25.1 0.0 0.011 15.4 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KXX83014.1 - 0.0012 17.7 0.0 0.026 13.3 0.0 2.0 1 1 1 2 2 2 2 Coatomer WD associated region zf-Nse PF11789.3 KXX83014.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Peripla_BP_2 PF01497.13 KXX83014.1 - 0.033 13.3 0.3 0.83 8.7 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein Rtf2 PF04641.7 KXX83014.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hemerythrin PF01814.18 KXX83014.1 - 0.21 11.7 3.1 0.5 10.5 0.7 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Peptidase_C14 PF00656.17 KXX83016.1 - 0.0005 19.8 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Caspase domain Raptor_N PF14538.1 KXX83016.1 - 0.027 14.3 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain SR-25 PF10500.4 KXX83016.1 - 2.6 7.4 13.2 4.7 6.6 9.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1777 PF08648.7 KXX83016.1 - 6.3 6.4 27.9 0.95 9.1 15.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) FAD_binding_3 PF01494.14 KXX83017.1 - 4.9e-11 42.2 0.3 0.00053 19.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KXX83017.1 - 7.6e-06 25.0 0.0 0.048 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX83017.1 - 1.2e-05 25.2 0.2 2.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KXX83017.1 - 0.002 18.5 0.1 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KXX83017.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KXX83017.1 - 0.074 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPD52 PF04201.10 KXX83018.1 - 0.34 10.6 4.8 0.58 9.8 3.3 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Abhydrolase_4 PF08386.5 KXX83019.1 - 4.6e-22 77.8 0.0 9.2e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KXX83019.1 - 1.2e-15 57.7 0.0 6.2e-14 52.1 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KXX83019.1 - 3.3e-09 36.9 1.5 1.2e-08 35.0 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 KXX83020.1 - 1.8e-13 50.7 0.8 3.4e-13 49.8 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX83020.1 - 0.00096 18.2 0.0 0.77 8.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KXX83020.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBM_19 PF03427.8 KXX83021.1 - 0.47 10.2 8.6 1.8 8.4 6.0 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) TFIIA PF03153.8 KXX83022.1 - 0.00012 22.1 12.9 0.00015 21.7 8.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 KXX83022.1 - 0.049 13.2 3.6 0.069 12.7 2.5 1.2 1 0 0 1 1 1 0 IncA protein Dapper PF15268.1 KXX83022.1 - 1.4 7.6 24.7 1.9 7.1 17.1 1.1 1 0 0 1 1 1 0 Dapper Macoilin PF09726.4 KXX83022.1 - 3.7 5.7 12.4 4.9 5.3 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M49 PF03571.10 KXX83023.1 - 9.5e-219 727.0 0.0 1.1e-218 726.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 KXX83023.1 - 0.16 11.8 0.2 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain SKI PF01202.17 KXX83024.1 - 1.9e-14 53.8 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 KXX83024.1 - 4.9e-13 49.9 0.0 8.3e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KXX83024.1 - 1.5e-10 41.5 0.0 2.7e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KXX83024.1 - 2e-09 37.4 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KXX83024.1 - 4e-05 22.4 0.0 5.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KXX83024.1 - 0.00032 20.9 0.2 0.0028 17.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KXX83024.1 - 0.00036 20.5 0.0 0.00054 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX83024.1 - 0.0006 19.9 0.0 0.00083 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KXX83024.1 - 0.00087 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.7 KXX83024.1 - 0.0009 18.9 0.0 0.0028 17.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KXX83024.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KXX83024.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KXX83024.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX83024.1 - 0.0026 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KXX83024.1 - 0.0031 17.3 0.0 0.0065 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KXX83024.1 - 0.0049 17.1 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 KXX83024.1 - 0.005 16.2 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin2 PF13189.1 KXX83024.1 - 0.0051 16.7 0.0 0.042 13.7 0.0 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_19 PF13245.1 KXX83024.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain CoaE PF01121.15 KXX83024.1 - 0.0078 15.6 0.0 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_29 PF13555.1 KXX83024.1 - 0.018 14.5 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 KXX83024.1 - 0.024 14.2 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 KXX83024.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KXX83024.1 - 0.036 13.7 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 KXX83024.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 1 0 Archaeal ATPase CPT PF07931.7 KXX83024.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 KXX83024.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_PrkA PF08298.6 KXX83024.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Zeta_toxin PF06414.7 KXX83024.1 - 0.12 11.4 0.0 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 KXX83024.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KXX83024.1 - 0.18 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain WLM PF08325.5 KXX83025.1 - 0.037 13.8 0.2 0.037 13.8 0.1 1.5 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.21 KXX83026.1 - 1.1e-26 91.5 32.2 1.5e-05 25.0 0.6 7.8 6 1 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX83026.1 - 5.7e-24 83.1 31.7 2.3e-07 30.7 0.1 6.6 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 KXX83026.1 - 1.9e-13 49.7 16.5 0.0023 17.7 0.1 5.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KXX83026.1 - 2.3e-13 49.4 46.5 0.0039 17.4 0.1 7.9 8 0 0 8 8 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX83026.1 - 8.1e-11 41.7 14.9 0.051 13.7 0.0 6.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KXX83026.1 - 0.091 12.4 10.8 4 7.2 0.2 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-met PF12874.2 KXX83026.1 - 0.11 12.7 29.9 0.32 11.2 0.2 6.7 6 1 1 7 7 7 0 Zinc-finger of C2H2 type NADH-G_4Fe-4S_3 PF10588.4 KXX83026.1 - 0.12 11.5 6.7 1.3 8.3 0.1 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C2H2_2 PF12756.2 KXX83026.1 - 0.13 12.3 18.3 0.5 10.5 0.5 5.1 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KXX83026.1 - 0.59 10.1 14.5 1.6 8.7 0.1 4.7 4 0 0 4 4 4 0 zinc-finger Rad50_zn_hook PF04423.9 KXX83026.1 - 2.4 7.7 5.5 0.55 9.7 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif HC2 PF07382.6 KXX83028.1 - 8.9e-06 25.6 27.4 8.9e-06 25.6 19.0 1.7 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Med3 PF11593.3 KXX83028.1 - 0.34 10.0 7.8 0.39 9.9 5.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1682 PF07946.9 KXX83028.1 - 5 5.8 16.1 8.6 5.1 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Dynamin_N PF00350.18 KXX83029.1 - 1e-23 83.9 0.0 1.9e-22 79.8 0.0 2.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KXX83029.1 - 7.9e-09 34.6 0.1 2.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KXX83029.1 - 0.0011 18.8 0.0 0.0071 16.2 0.0 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain AAA_21 PF13304.1 KXX83029.1 - 0.013 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KXX83029.1 - 0.018 15.5 0.0 0.061 13.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KXX83029.1 - 0.029 14.6 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 KXX83029.1 - 0.032 14.1 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KXX83029.1 - 0.033 13.7 0.2 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Latarcin PF10279.4 KXX83029.1 - 1.7 8.8 9.1 3 8.0 0.8 3.6 3 0 0 3 3 3 0 Latarcin precursor NTP_transferase PF00483.18 KXX83030.1 - 4.9e-29 101.3 0.0 6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KXX83030.1 - 1e-07 31.0 6.8 3e-06 26.4 0.0 3.8 4 0 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KXX83030.1 - 1.5e-06 28.4 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 KXX83030.1 - 0.024 14.1 0.0 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.21 KXX83030.1 - 0.088 12.4 0.1 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF964 PF06133.6 KXX83031.1 - 0.053 13.5 0.1 0.078 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF964) F-box PF00646.28 KXX83032.1 - 1.8e-11 43.3 3.2 3.7e-11 42.3 2.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KXX83032.1 - 2.8e-08 33.3 2.4 2.8e-08 33.3 1.6 1.9 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KXX83032.1 - 0.0083 15.8 0.4 0.019 14.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like domain PRANC PF09372.5 KXX83032.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PRANC domain zf-C2H2_jaz PF12171.3 KXX83033.1 - 0.0028 17.7 0.1 0.0043 17.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Med7 PF05983.6 KXX83034.1 - 9.7e-49 165.2 0.2 1.2e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 MED7 protein DUF1759 PF03564.10 KXX83034.1 - 0.1 12.3 0.9 0.2 11.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Proteasome PF00227.21 KXX83035.1 - 1.2e-60 204.1 0.1 1.5e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KXX83035.1 - 1.2e-14 53.3 0.2 4.1e-14 51.5 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KXX83035.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 KXX83036.1 - 1.5e-24 86.0 1.8 1.5e-24 86.0 1.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily FtsX PF02687.16 KXX83036.1 - 0.21 11.3 2.4 6.4 6.5 0.4 2.9 3 0 0 3 3 3 0 FtsX-like permease family RseC_MucC PF04246.7 KXX83036.1 - 0.27 10.8 2.0 3.6 7.1 0.4 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF2975 PF11188.3 KXX83036.1 - 0.57 9.9 4.2 2.1 8.0 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Virul_fac_BrkB PF03631.10 KXX83036.1 - 5.8 6.2 9.1 0.54 9.5 2.8 1.7 2 0 0 2 2 2 0 Virulence factor BrkB WD40 PF00400.27 KXX83037.1 - 2.3e-54 179.4 17.6 7.2e-09 35.1 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KXX83037.1 - 4.2e-12 45.5 0.5 8e-12 44.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX83037.1 - 4.3e-11 42.1 1.1 1.4e-10 40.5 0.5 2.1 2 1 1 3 3 3 1 F-box domain PQQ_2 PF13360.1 KXX83037.1 - 0.0001 21.8 1.0 1.4 8.3 0.0 3.3 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 KXX83037.1 - 0.004 15.3 9.3 2.9 5.9 0.1 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PRANC PF09372.5 KXX83037.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 PRANC domain CDtoxinA PF03498.9 KXX83037.1 - 0.23 10.8 2.1 7.1 5.9 0.0 2.7 2 1 1 3 3 3 0 Cytolethal distending toxin A/C family UMPH-1 PF05822.7 KXX83037.1 - 0.31 10.3 0.0 0.63 9.3 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) zf-C2H2_4 PF13894.1 KXX83038.1 - 0.012 15.9 1.4 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KXX83038.1 - 0.016 15.4 2.3 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PLA1 PF02253.10 KXX83038.1 - 0.063 12.6 0.1 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase A1 zf-C2H2_jaz PF12171.3 KXX83038.1 - 0.23 11.6 1.4 0.78 9.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KXX83038.1 - 2.4 8.0 4.3 2 8.2 1.5 2.0 2 0 0 2 2 2 0 BED zinc finger Pro_CA PF00484.14 KXX83039.1 - 1.3e-05 25.2 0.2 1.6e-05 24.9 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ACP PF06857.6 KXX83039.1 - 0.083 12.8 0.0 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Cutinase PF01083.17 KXX83040.1 - 1.8e-53 180.9 0.0 2.1e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KXX83040.1 - 0.00079 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 KXX83040.1 - 0.057 13.1 0.0 0.065 12.9 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 KXX83040.1 - 0.057 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 KXX83040.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX83041.1 - 1.1e-21 77.7 4.9 1.3e-21 77.4 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX83041.1 - 4.7e-11 42.6 0.3 5.8e-11 42.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX83041.1 - 9.7e-07 28.5 0.0 9.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KXX83041.1 - 5.2e-05 22.7 0.0 8.4e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 KXX83041.1 - 0.0006 20.1 0.1 0.00092 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.13 KXX83041.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KXX83041.1 - 0.03 14.1 0.0 0.098 12.5 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase zf-U1 PF06220.7 KXX83043.1 - 2.7e-07 30.0 0.4 4.3e-07 29.3 0.3 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF4140 PF13600.1 KXX83043.1 - 9.2 6.7 11.8 2 8.8 0.4 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) PIR PF00399.14 KXX83045.1 - 0.0025 17.1 0.5 0.0025 17.1 0.4 3.6 3 0 0 3 3 3 2 Yeast PIR protein repeat HET PF06985.6 KXX83047.1 - 5.5e-16 58.9 0.0 8.5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L6e PF01159.14 KXX83048.1 - 1.6e-37 128.0 0.2 2.4e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.3 KXX83049.1 - 8e-12 45.0 0.2 8e-12 45.0 0.1 3.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus SATase_N PF06426.9 KXX83049.1 - 0.028 14.6 2.1 0.24 11.6 0.3 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal STAT_alpha PF01017.15 KXX83049.1 - 0.052 13.2 1.6 0.39 10.4 0.5 2.3 2 1 0 2 2 2 0 STAT protein, all-alpha domain Adaptin_binding PF10199.4 KXX83049.1 - 0.071 13.3 0.9 0.11 12.8 0.6 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 APG6 PF04111.7 KXX83049.1 - 0.57 9.1 3.2 0.79 8.7 2.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 CorA PF01544.13 KXX83049.1 - 5.2 6.0 8.0 2.9 6.8 3.8 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein STT3 PF02516.9 KXX83050.1 - 5.5e-132 441.1 38.2 2.5e-127 425.8 24.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 KXX83050.1 - 6.5e-05 22.4 14.7 6.5e-05 22.4 10.2 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytomega_TRL10 PF06084.6 KXX83050.1 - 1.1 9.0 2.1 1 9.1 0.1 1.9 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Ribosomal_L29 PF00831.18 KXX83051.1 - 1.6e-17 62.8 1.4 1.6e-17 62.8 1.0 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KXX83051.1 - 0.027 14.7 1.8 0.033 14.4 1.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Snapin_Pallidin PF14712.1 KXX83051.1 - 1.7 8.9 6.7 0.17 12.2 1.0 1.8 1 1 1 2 2 2 0 Snapin/Pallidin FlxA PF14282.1 KXX83051.1 - 4.6 7.2 7.5 0.37 10.7 2.1 1.5 2 0 0 2 2 2 0 FlxA-like protein RhoGAP PF00620.22 KXX83052.1 - 2.8e-37 127.6 0.0 7.5e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KXX83052.1 - 5.4e-30 103.2 36.7 2.3e-12 46.7 4.3 5.1 5 0 0 5 5 5 4 LIM domain 3Beta_HSD PF01073.14 KXX83053.1 - 3.2e-64 216.3 0.0 3.8e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KXX83053.1 - 1.5e-32 112.9 0.5 2.1e-32 112.4 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KXX83053.1 - 2.4e-16 59.4 3.1 4.6e-14 51.9 0.4 2.1 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KXX83053.1 - 7.8e-14 51.2 0.3 1.1e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KXX83053.1 - 1.2e-13 51.5 0.1 1.7e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KXX83053.1 - 1.1e-07 31.0 0.7 1.4e-06 27.4 0.4 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KXX83053.1 - 1.3e-06 28.4 0.4 1.3e-06 28.4 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KXX83053.1 - 0.00015 21.1 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.11 KXX83053.1 - 0.00022 21.5 0.1 0.00045 20.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain KR PF08659.5 KXX83053.1 - 0.00027 20.6 1.8 0.00084 19.0 1.2 1.8 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 KXX83053.1 - 0.00056 19.8 0.1 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KXX83053.1 - 0.0017 17.3 0.2 0.0025 16.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KXX83053.1 - 0.016 15.0 0.4 0.035 14.0 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sec63 PF02889.11 KXX83054.1 - 2e-193 641.5 0.0 4e-109 364.6 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KXX83054.1 - 4.7e-54 182.3 1.0 8.9e-31 106.6 0.0 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 KXX83054.1 - 1.5e-18 67.2 0.0 6.4e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KXX83054.1 - 2.3e-10 40.1 0.0 1.9e-08 34.0 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KXX83054.1 - 1.5e-07 31.6 1.3 0.0029 17.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 KXX83054.1 - 6.2e-05 22.0 0.0 0.085 11.7 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KXX83054.1 - 0.0002 20.9 1.1 1.8 7.9 0.0 4.7 3 3 2 5 5 5 2 AAA-like domain AAA_19 PF13245.1 KXX83054.1 - 0.0013 18.4 0.0 0.16 11.6 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 KXX83054.1 - 0.0015 17.7 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 KXX83054.1 - 0.0057 16.1 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family UvrD-helicase PF00580.16 KXX83054.1 - 0.009 15.3 0.0 1.7 7.8 0.0 2.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_23 PF13476.1 KXX83054.1 - 0.86 9.8 6.2 19 5.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain TMCO5 PF14992.1 KXX83055.1 - 0.1 11.6 1.0 0.24 10.4 0.7 1.6 1 0 0 1 1 1 0 TMCO5 family PWWP PF00855.12 KXX83056.1 - 9.5e-13 48.1 0.0 9.5e-13 48.1 0.0 2.7 3 0 0 3 3 3 1 PWWP domain ORC3_N PF07034.6 KXX83057.1 - 2.6e-37 128.5 0.0 4.8e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF2417 PF10329.4 KXX83058.1 - 6e-87 290.8 3.4 7.7e-87 290.5 2.4 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KXX83058.1 - 1.3e-05 25.2 3.0 1.7e-05 24.7 0.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family ABC2_membrane_3 PF12698.2 KXX83058.1 - 0.12 11.3 8.7 0.19 10.7 6.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Sdh_cyt PF01127.17 KXX83058.1 - 7 6.5 14.6 11 5.8 0.8 3.0 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4632 PF15451.1 KXX83059.1 - 0.31 10.9 5.7 15 5.6 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) UQ_con PF00179.21 KXX83060.1 - 9.5e-40 135.2 0.0 7.9e-28 96.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 KXX83060.1 - 0.00015 21.5 0.0 0.19 11.6 0.0 2.5 1 1 1 2 2 2 2 RWD domain Prok-E2_B PF14461.1 KXX83060.1 - 0.017 14.8 0.0 0.71 9.6 0.0 2.4 2 1 0 2 2 2 0 Prokaryotic E2 family B AAA PF00004.24 KXX83061.1 - 2.6e-16 60.0 0.0 8.9e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KXX83061.1 - 2.8e-13 49.8 0.0 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KXX83061.1 - 2.7e-12 46.4 0.0 5.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 KXX83061.1 - 1.6e-06 28.2 0.1 0.0001 22.4 0.0 2.8 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KXX83061.1 - 2.3e-06 26.8 0.0 4.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KXX83061.1 - 1.2e-05 24.9 0.0 3.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KXX83061.1 - 1.2e-05 24.2 0.0 0.0027 16.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 KXX83061.1 - 3.5e-05 23.4 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KXX83061.1 - 3.6e-05 23.8 0.0 0.00096 19.1 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KXX83061.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KXX83061.1 - 0.00022 20.4 0.0 0.0093 15.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KXX83061.1 - 0.0021 17.5 0.2 0.028 13.8 0.0 2.4 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KXX83061.1 - 0.0026 18.5 0.0 0.0064 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KXX83061.1 - 0.0032 17.0 0.3 0.0077 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KXX83061.1 - 0.0043 16.7 0.1 0.028 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KXX83061.1 - 0.0055 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 KXX83061.1 - 0.0064 15.4 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KXX83061.1 - 0.011 15.1 0.1 0.042 13.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KXX83061.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KXX83061.1 - 0.025 14.9 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 KXX83061.1 - 0.027 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TMP_2 PF06791.8 KXX83061.1 - 0.036 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_30 PF13604.1 KXX83061.1 - 0.049 13.2 0.0 0.25 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KXX83061.1 - 0.073 12.6 0.0 0.39 10.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KXX83061.1 - 0.074 11.8 0.0 2.7 6.7 0.0 2.6 3 0 0 3 3 3 0 SNF2 family N-terminal domain AAA_10 PF12846.2 KXX83061.1 - 0.082 12.3 0.0 1.1 8.6 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KXX83061.1 - 0.086 12.7 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KXX83061.1 - 0.095 12.5 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KXX83061.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase LAMTOR PF15454.1 KXX83062.1 - 4.7e-18 65.2 0.2 8.6e-18 64.3 0.2 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF964 PF06133.6 KXX83062.1 - 0.011 15.7 0.7 0.019 14.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF964) VWA_2 PF13519.1 KXX83063.1 - 4.4e-05 23.6 0.2 7.8e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tagatose_6_P_K PF08013.6 KXX83063.1 - 0.024 13.0 0.0 0.042 12.2 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Beta-lactamase PF00144.19 KXX83065.1 - 4.9e-28 98.1 0.3 8.2e-27 94.0 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase PAN_4 PF14295.1 KXX83066.1 - 2.3e-07 30.4 0.3 4.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 PAN domain MANEC PF07502.9 KXX83066.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 MANEC domain Cytochrom_B_N PF00033.14 KXX83066.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PAN_1 PF00024.21 KXX83066.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 PAN domain Nuc_deoxyrib_tr PF05014.10 KXX83067.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Sushi PF00084.15 KXX83067.1 - 0.032 14.5 0.1 0.072 13.4 0.1 1.5 1 0 0 1 1 1 0 Sushi domain (SCR repeat) DUF434 PF04256.7 KXX83067.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) HET PF06985.6 KXX83068.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF3716 PF12511.3 KXX83069.1 - 4.4e-15 55.0 5.0 4.4e-15 55.0 3.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Gpi16 PF04113.9 KXX83070.1 - 5.6e-244 810.3 0.0 7.1e-244 810.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 KXX83071.1 - 6e-69 232.3 0.1 7.2e-69 232.1 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 KXX83071.1 - 0.028 15.1 0.6 0.13 13.0 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain zf-C4H2 PF10146.4 KXX83071.1 - 0.036 14.1 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein HR1 PF02185.11 KXX83071.1 - 0.11 12.2 0.2 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Hr1 repeat FAD_binding_3 PF01494.14 KXX83073.1 - 1.3e-06 27.7 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_M43 PF05572.8 KXX83076.1 - 2.5e-13 49.8 0.1 5.4e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M7 PF02031.11 KXX83076.1 - 0.00012 21.7 0.5 0.00027 20.6 0.4 1.6 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_5 PF13688.1 KXX83076.1 - 0.00027 20.9 1.0 0.00064 19.6 0.6 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KXX83076.1 - 0.00044 20.3 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KXX83076.1 - 0.00062 19.3 0.2 0.001 18.6 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KXX83076.1 - 0.0011 19.5 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KXX83076.1 - 0.02 14.5 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin Astacin PF01400.19 KXX83076.1 - 0.17 11.2 0.3 0.31 10.3 0.2 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) adh_short_C2 PF13561.1 KXX83077.1 - 1.3e-27 97.1 0.0 1.6e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KXX83077.1 - 1e-18 67.8 0.8 1.4e-18 67.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX83077.1 - 0.0077 15.9 0.3 0.015 14.9 0.2 1.6 1 1 0 1 1 1 1 KR domain RNase_T PF00929.19 KXX83078.1 - 3.9e-06 27.2 0.0 4.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease MARVEL PF01284.18 KXX83079.1 - 8.9e-07 28.8 17.8 3e-06 27.1 12.3 1.8 1 1 1 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 KXX83079.1 - 0.011 15.3 4.6 0.011 15.3 3.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF588) Peptidase_M56 PF05569.6 KXX83079.1 - 0.019 13.9 1.5 0.026 13.5 0.2 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 Pkinase PF00069.20 KXX83081.1 - 3.2e-06 26.5 0.0 4.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KXX83081.1 - 0.075 12.0 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIS_M PF07500.9 KXX83082.1 - 1.9e-18 66.6 0.2 4.8e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KXX83082.1 - 4.6e-17 62.6 0.0 1.1e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KXX83082.1 - 3.1e-09 36.3 8.1 5.9e-09 35.4 5.6 1.5 1 0 0 1 1 1 1 PHD-finger 2-oxoacid_dh PF00198.18 KXX83083.1 - 8.6e-74 247.6 0.0 1.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KXX83083.1 - 1.7e-17 62.8 0.2 3.3e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KXX83083.1 - 1.3e-11 43.9 0.0 3.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 KXX83083.1 - 0.13 12.5 0.2 0.74 10.0 0.0 2.2 2 1 0 2 2 2 0 Brain expressed X-linked like family ATP-synt_10 PF05176.9 KXX83084.1 - 5.4e-89 297.7 0.0 6.9e-89 297.4 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein RTC PF01137.16 KXX83085.1 - 4.2e-27 94.4 4.1 1.8e-26 92.3 1.5 2.0 1 1 1 2 2 2 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KXX83085.1 - 4e-21 74.9 0.1 1.1e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.5 KXX83086.1 - 3.3e-40 136.6 2.2 5.3e-40 135.9 1.6 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CPSase_L_D2 PF02786.12 KXX83087.1 - 1.1e-110 367.9 0.1 3.9e-84 281.1 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KXX83087.1 - 1.5e-40 137.8 0.0 3.6e-40 136.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KXX83087.1 - 5.3e-40 137.1 0.1 1.1e-22 80.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KXX83087.1 - 4.1e-35 120.2 0.0 3.6e-16 59.2 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KXX83087.1 - 9.7e-26 90.2 0.0 2.5e-09 36.3 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KXX83087.1 - 3.5e-22 78.5 0.1 4.7e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KXX83087.1 - 3.3e-18 65.8 0.6 2.2e-09 37.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KXX83087.1 - 7.7e-09 35.3 0.0 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KXX83087.1 - 1.3e-06 28.3 0.2 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KXX83087.1 - 3.9e-06 26.5 0.4 0.049 13.1 0.1 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KXX83087.1 - 8.1e-05 21.9 0.1 0.16 11.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Epimerase PF01370.16 KXX83087.1 - 0.008 15.6 0.1 0.42 10.0 0.0 2.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NPL4 PF05021.10 KXX83088.1 - 4.3e-131 436.6 0.0 5.5e-131 436.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KXX83088.1 - 7.5e-73 243.0 0.2 1.3e-72 242.2 0.2 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KXX83088.1 - 4.4e-05 23.6 0.0 0.00015 21.9 0.0 1.9 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 KXX83088.1 - 0.06 13.1 0.4 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Metallophos_2 PF12850.2 KXX83089.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX83089.1 - 1e-08 34.8 0.5 2.8e-07 30.1 0.3 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ad_cyc_g-alpha PF08509.6 KXX83090.1 - 0.095 12.0 0.3 0.29 10.4 0.2 1.9 1 1 0 1 1 1 0 Adenylate cyclase G-alpha binding domain DUF3446 PF11928.3 KXX83090.1 - 3.5 7.8 12.0 1.4e+02 2.7 8.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) DUF4187 PF13821.1 KXX83091.1 - 2.7e-17 62.0 1.8 2.7e-17 62.0 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KXX83091.1 - 0.011 15.4 1.4 0.03 14.0 1.0 1.8 1 0 0 1 1 1 0 G-patch domain PPR_2 PF13041.1 KXX83092.1 - 1.1e-08 34.8 5.4 2.6e-07 30.5 0.0 4.5 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 KXX83092.1 - 0.002 17.9 7.4 0.0095 15.8 0.0 5.2 6 0 0 6 6 6 1 PPR repeat UPF0184 PF03670.8 KXX83092.1 - 0.053 13.6 0.4 0.85 9.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) PPR_3 PF13812.1 KXX83092.1 - 0.75 10.2 12.1 1.8 9.0 0.0 6.2 8 0 0 8 8 8 0 Pentatricopeptide repeat domain Sec66 PF09802.4 KXX83093.1 - 8.8e-80 266.5 0.1 1e-79 266.3 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DEAD PF00270.24 KXX83096.1 - 9.6e-47 158.6 0.0 1.6e-44 151.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX83096.1 - 2.7e-24 84.7 0.0 5.4e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX83096.1 - 0.00064 19.6 0.1 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KXX83096.1 - 0.0031 16.3 0.0 0.0063 15.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain RAP1 PF07218.6 KXX83096.1 - 0.81 7.7 3.1 1.7 6.6 2.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LRR_6 PF13516.1 KXX83097.1 - 0.0007 19.4 8.8 1.2e+02 3.2 0.0 8.4 9 0 0 9 9 9 0 Leucine Rich repeat OmpH PF03938.9 KXX83097.1 - 0.00088 19.2 2.0 0.0026 17.7 1.4 1.8 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) LRR_4 PF12799.2 KXX83097.1 - 0.025 14.2 1.7 3.8 7.2 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_L18p PF00861.17 KXX83098.1 - 6.5e-43 145.7 1.3 1.3e-42 144.7 0.0 2.1 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KXX83098.1 - 1.3e-32 112.1 7.5 1.3e-32 112.1 5.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4297 PF14130.1 KXX83098.1 - 0.011 15.6 0.8 0.017 15.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) Med1 PF10744.4 KXX83099.1 - 2.6e-38 131.8 0.0 8e-38 130.2 0.0 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Med15 PF09606.5 KXX83100.1 - 0.0018 16.6 34.0 0.0025 16.1 23.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 KXX83100.1 - 0.023 14.7 18.3 0.058 13.4 12.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 KXX83100.1 - 0.086 11.2 4.0 0.1 11.0 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endostatin PF06482.6 KXX83100.1 - 0.23 10.7 7.2 0.52 9.6 5.0 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EIIBC-GUT_N PF03612.9 KXX83100.1 - 2 8.0 4.9 4.7 6.7 3.4 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex19 PF04614.7 KXX83101.1 - 1.9e-74 250.4 15.2 2.8e-74 249.8 10.6 1.2 1 0 0 1 1 1 1 Pex19 protein family Gluconate_2-dh3 PF13618.1 KXX83101.1 - 1 9.4 8.6 5 7.2 2.5 2.8 1 1 1 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF737 PF05300.6 KXX83101.1 - 6.9 6.5 10.6 44 3.9 6.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Pkinase PF00069.20 KXX83102.1 - 8.8e-46 156.1 0.0 9.1e-42 142.9 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KXX83102.1 - 3.3e-22 78.8 0.0 8.2e-22 77.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KXX83102.1 - 0.0013 17.7 0.0 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KXX83102.1 - 0.061 13.0 0.1 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KXX83103.1 - 3.3e-37 126.6 0.0 6.1e-15 55.3 0.0 4.0 3 1 1 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KXX83103.1 - 6.4e-31 104.6 0.0 4.2e-06 26.2 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KXX83103.1 - 3.6e-22 77.8 0.1 4.6e-09 36.2 0.0 5.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX83103.1 - 2.6e-21 75.5 0.0 6.5e-06 26.5 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KXX83103.1 - 6.5e-21 72.3 0.0 3.8e-05 23.5 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.7 KXX83103.1 - 2.3e-10 40.3 0.1 2.4e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KXX83103.1 - 3.1e-07 30.5 0.0 1.6e-06 28.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KXX83103.1 - 0.00027 21.0 0.0 0.0072 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KXX83103.1 - 0.0016 18.5 0.0 0.013 15.6 0.0 2.5 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 KXX83103.1 - 0.03 13.7 0.0 0.58 9.5 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain FAM196 PF15265.1 KXX83103.1 - 0.052 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 FAM196 family AAA_14 PF13173.1 KXX83103.1 - 0.12 12.2 0.2 0.41 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Formyl_trans_N PF00551.14 KXX83105.1 - 1.7e-24 86.3 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.27 KXX83106.1 - 6.1e-71 231.9 11.6 2.2e-10 39.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KXX83106.1 - 1.2e-08 33.5 1.1 0.00091 17.4 0.0 4.2 2 2 2 4 4 4 4 Nucleoporin Nup120/160 bZIP_2 PF07716.10 KXX83106.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF2881 PF11087.3 KXX83106.1 - 0.25 10.8 1.6 0.48 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) Pescadillo_N PF06732.6 KXX83107.1 - 1.1e-113 379.2 0.2 1.1e-113 379.2 0.1 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KXX83107.1 - 2.1e-07 30.9 0.0 9e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Astro_capsid PF03115.9 KXX83107.1 - 0.26 9.4 7.0 0.38 8.9 4.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PIG-U PF06728.8 KXX83108.1 - 2.9e-123 411.5 26.6 3.3e-123 411.3 18.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pyridoxal_deC PF00282.14 KXX83110.1 - 2.3e-14 52.6 0.1 4.8e-11 41.7 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DHquinase_I PF01487.10 KXX83111.1 - 3.6e-58 196.8 0.0 5e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase GidB PF02527.10 KXX83111.1 - 0.0039 16.3 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PhoD PF09423.5 KXX83112.1 - 1.7e-05 23.5 0.0 0.0001 21.0 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase Cid2 PF09774.4 KXX83112.1 - 0.22 11.6 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Caffeine-induced death protein 2 HNH_2 PF13391.1 KXX83113.1 - 9.3e-06 25.3 0.2 2.9e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 HNH endonuclease CxxCxxCC PF03692.10 KXX83113.1 - 0.11 12.9 1.2 0.16 12.5 0.1 1.8 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain UPF0183 PF03676.9 KXX83114.1 - 3.3e-34 118.1 0.1 1.3e-18 66.7 0.0 5.4 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) HAD_2 PF13419.1 KXX83115.1 - 1.7e-22 80.4 0.0 2.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KXX83115.1 - 0.14 12.5 0.0 0.65 10.3 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ATG2_CAD PF13329.1 KXX83116.1 - 1.7e-46 157.6 0.0 4.1e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KXX83116.1 - 7e-29 99.8 0.3 7e-29 99.8 0.2 3.0 3 0 0 3 3 3 1 ATG C terminal domain Phage_attach PF05354.6 KXX83116.1 - 0.001 18.5 0.1 0.54 9.8 0.0 3.4 3 0 0 3 3 3 1 Phage Head-Tail Attachment Chorein_N PF12624.2 KXX83116.1 - 0.0033 16.9 0.1 0.082 12.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Presenilin PF01080.12 KXX83116.1 - 8.2 5.1 3.6 2.4 6.8 0.0 1.8 2 0 0 2 2 2 0 Presenilin zf-UBR PF02207.15 KXX83117.1 - 2.2e-16 59.2 4.4 2.2e-16 59.2 3.0 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Acyl-CoA_dh_1 PF00441.19 KXX83118.1 - 8.1e-34 116.8 0.9 1.2e-33 116.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KXX83118.1 - 3.5e-20 71.5 0.1 7.8e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KXX83118.1 - 7.2e-16 57.4 0.5 1.4e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KXX83118.1 - 6.3e-05 23.5 0.1 0.00049 20.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KXX83118.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.19 KXX83119.1 - 1.5e-48 166.0 1.7 3.8e-46 158.0 1.2 2.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KXX83119.1 - 1.8e-15 56.6 0.1 3.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KXX83119.1 - 7.2e-08 32.3 0.3 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KXX83119.1 - 1.6e-06 27.3 0.0 0.00026 19.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KXX83119.1 - 5.2e-06 26.6 0.1 0.00073 19.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX83119.1 - 2.3e-05 23.0 0.1 0.0014 17.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KXX83119.1 - 4.6e-05 23.7 0.2 0.00013 22.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KXX83119.1 - 0.00037 20.4 0.0 0.0054 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KXX83119.1 - 0.0007 18.5 0.1 0.0018 17.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KXX83119.1 - 0.00097 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KXX83119.1 - 0.0027 16.8 0.1 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KXX83119.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KXX83119.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KXX83119.1 - 0.06 12.2 0.3 0.67 8.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KXX83119.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KXX83119.1 - 0.2 11.6 0.2 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding GIDA PF01134.17 KXX83119.1 - 0.2 10.4 0.1 0.54 9.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Tom37_C PF11801.3 KXX83120.1 - 1.9e-18 66.9 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KXX83120.1 - 3.9e-17 62.2 0.2 1.2e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein tRNA-synt_1 PF00133.17 KXX83121.1 - 8.5e-147 489.7 0.0 1.2e-146 489.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KXX83121.1 - 2.4e-21 75.8 0.0 6.4e-12 44.8 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KXX83121.1 - 2.5e-19 69.5 0.0 4.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KXX83121.1 - 1.2e-05 24.7 3.5 2.4e-05 23.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KXX83121.1 - 0.014 14.5 0.0 0.44 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 KXX83122.1 - 4.2e-25 88.1 0.0 1.4e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KXX83122.1 - 1.3e-23 82.6 0.1 5.6e-23 80.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KXX83122.1 - 9.8e-05 22.2 0.7 0.00084 19.2 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit SPRY PF00622.23 KXX83123.1 - 0.00034 20.7 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.19 KXX83124.1 - 1.2e-19 70.3 16.4 7.2e-16 58.0 8.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HABP4_PAI-RBP1 PF04774.10 KXX83126.1 - 0.00032 21.1 2.1 0.00058 20.3 1.5 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CIAPIN1 PF05093.8 KXX83127.1 - 3.2e-35 120.2 4.5 4.7e-35 119.6 3.1 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RNA_Me_trans PF04252.8 KXX83128.1 - 2.4e-47 160.9 0.0 2.7e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DHO_dh PF01180.16 KXX83129.1 - 8.4e-18 64.3 0.0 1.5e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Abhydrolase_2 PF02230.11 KXX83130.1 - 1.1e-29 103.4 0.0 2.1e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX83130.1 - 3.8e-10 40.0 0.8 5.4e-10 39.5 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX83130.1 - 1.4e-08 34.6 0.6 2.7e-08 33.6 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KXX83130.1 - 0.00011 21.8 0.2 0.00016 21.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX83130.1 - 0.0013 17.9 0.0 1.9 7.6 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family LIP PF03583.9 KXX83130.1 - 0.11 11.6 0.2 3 6.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase APH PF01636.18 KXX83131.1 - 1.3e-08 34.8 1.8 8.2e-08 32.2 0.2 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KXX83131.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1759 PF03564.10 KXX83131.1 - 0.06 13.1 0.2 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) EcKinase PF02958.15 KXX83131.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Syja_N PF02383.13 KXX83132.1 - 4e-91 305.1 0.0 5e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 KXX83133.1 - 1.4e-58 196.8 0.2 1.6e-58 196.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KXX83133.1 - 3.3e-19 69.5 0.1 7.1e-19 68.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KXX83133.1 - 2e-15 56.4 0.1 2.4e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KXX83133.1 - 4.3e-08 32.5 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KXX83133.1 - 7.8e-08 31.9 0.0 1.1e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KXX83133.1 - 1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX83133.1 - 0.024 13.8 0.3 0.11 11.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KXX83133.1 - 0.035 14.2 0.1 2.7 8.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 KXX83133.1 - 0.13 10.9 0.3 9.3 4.8 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit DUF3115 PF11312.3 KXX83134.1 - 3.7e-93 311.8 0.0 5e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 KXX83135.1 - 1.3e-152 507.4 0.0 1.8e-152 506.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KXX83135.1 - 4.5e-45 153.3 0.0 7.3e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KXX83135.1 - 2.8e-15 56.3 0.0 5.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KXX83135.1 - 6.5e-06 25.2 0.0 0.00049 19.1 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KXX83135.1 - 0.00037 20.0 0.9 0.0032 17.0 0.1 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_tran PF00005.22 KXX83135.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Filament PF00038.16 KXX83136.1 - 0.00047 19.7 10.2 0.00047 19.7 7.1 4.7 3 1 2 5 5 5 2 Intermediate filament protein Reo_sigmaC PF04582.7 KXX83136.1 - 0.0096 15.1 6.3 0.052 12.7 2.1 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein TcdB_N PF12918.2 KXX83136.1 - 0.012 15.7 0.8 0.19 11.8 0.1 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain COG5 PF10392.4 KXX83136.1 - 0.033 14.1 1.2 0.033 14.1 0.8 2.9 1 1 0 2 2 2 0 Golgi transport complex subunit 5 bZIP_1 PF00170.16 KXX83136.1 - 0.1 12.5 0.3 0.1 12.5 0.2 7.1 8 1 0 8 8 8 0 bZIP transcription factor Baculo_PEP_C PF04513.7 KXX83136.1 - 0.15 11.8 4.5 7 6.4 0.2 3.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 KXX83136.1 - 0.83 8.9 5.6 1.5 8.1 0.7 3.0 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) COG2 PF06148.6 KXX83136.1 - 5.3 6.9 17.7 14 5.5 2.7 3.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP-synt_C PF00137.16 KXX83139.1 - 9.2e-31 105.5 32.2 1.7e-18 66.2 9.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KXX83139.1 - 0.6 9.6 4.6 0.17 11.4 0.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_L7Ae PF01248.21 KXX83140.1 - 1.5e-25 88.5 0.1 1.8e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KXX83140.1 - 0.00047 20.0 0.2 0.0024 17.7 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 Syja_N PF02383.13 KXX83141.1 - 9.5e-98 326.8 0.0 1.3e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KXX83141.1 - 1.7e-35 120.8 0.0 3.4e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Abhydrolase_6 PF12697.2 KXX83142.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 KXX83142.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KXX83143.1 - 1.1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KXX83143.1 - 0.00029 20.7 2.5 0.0004 20.3 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX83143.1 - 0.0017 18.1 0.3 0.0025 17.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KXX83143.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase MCM PF00493.18 KXX83144.1 - 5e-139 462.7 0.0 5e-139 462.7 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM2_N PF12619.3 KXX83144.1 - 1.2e-31 109.8 39.4 1.2e-31 109.8 27.3 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KXX83144.1 - 3.7e-21 75.8 0.1 8.8e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX83144.1 - 9.6e-08 31.4 0.0 6e-06 25.5 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KXX83144.1 - 2.2e-06 27.4 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KXX83144.1 - 0.0016 17.9 0.2 0.011 15.2 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KXX83144.1 - 0.0019 17.7 0.1 0.019 14.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 KXX83144.1 - 0.061 12.5 1.2 0.15 11.3 0.8 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 KXX83144.1 - 0.23 11.8 0.6 0.73 10.2 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain HAD_2 PF13419.1 KXX83145.1 - 4.2e-15 56.4 0.0 2.5e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KXX83145.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like CHAT PF12770.2 KXX83146.1 - 1.9e-31 109.2 0.0 4.3e-31 108.1 0.0 1.5 1 1 0 1 1 1 1 CHAT domain POM121 PF15229.1 KXX83146.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.5 2 0 0 2 2 2 0 POM121 family TPR_12 PF13424.1 KXX83147.1 - 2.3e-10 40.2 13.1 0.032 14.1 0.0 8.1 5 3 3 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 KXX83147.1 - 0.014 14.9 3.2 23 4.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Laminin_I PF06008.9 KXX83147.1 - 0.021 14.1 3.7 0.055 12.7 1.0 2.6 3 0 0 3 3 3 0 Laminin Domain I TPR_2 PF07719.12 KXX83147.1 - 0.15 12.0 9.2 24 5.1 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KXX83147.1 - 0.23 12.2 0.2 0.23 12.2 0.1 8.5 10 3 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.1 KXX83147.1 - 0.44 11.2 0.0 0.44 11.2 0.0 6.9 7 1 0 7 7 7 0 Tetratricopeptide repeat Peptidase_S10 PF00450.17 KXX83148.1 - 7.5e-113 377.8 0.0 1.1e-112 377.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KXX83148.1 - 0.0019 18.0 0.0 0.0099 15.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family RCR PF12273.3 KXX83148.1 - 0.18 12.3 0.9 0.48 10.9 0.2 2.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TPR_2 PF07719.12 KXX83149.1 - 4.1e-10 38.7 2.2 0.00017 21.2 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KXX83149.1 - 1.2e-09 37.6 0.6 4.5e-05 23.0 0.0 3.9 2 1 3 5 5 5 3 TPR repeat TPR_19 PF14559.1 KXX83149.1 - 1.6e-09 37.9 0.3 0.0033 17.7 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX83149.1 - 1.7e-07 31.2 9.1 0.0086 16.6 0.2 5.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KXX83149.1 - 6.7e-06 26.6 11.6 8.9e-05 23.0 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KXX83149.1 - 6.6e-05 22.7 0.8 0.081 12.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KXX83149.1 - 0.0045 17.0 0.1 0.45 10.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KXX83149.1 - 0.035 14.5 0.4 1.2e+02 3.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KXX83149.1 - 0.11 12.6 1.8 1.7 8.8 0.0 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 KXX83149.1 - 0.12 12.6 0.1 0.5 10.7 0.0 2.2 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_9 PF13371.1 KXX83149.1 - 0.13 12.1 3.9 1.5 8.6 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TGT PF01702.13 KXX83150.1 - 4.8e-14 52.2 0.0 1.6e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase CN_hydrolase PF00795.17 KXX83151.1 - 2.2e-15 56.5 0.0 3.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.17 KXX83152.1 - 1.4e-10 40.8 0.0 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DKCLD PF08068.7 KXX83153.1 - 2.4e-30 104.2 0.2 1.2e-29 102.0 0.2 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KXX83153.1 - 2.2e-24 86.3 0.3 1.6e-21 76.9 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KXX83153.1 - 6.5e-21 73.8 0.7 1.2e-20 73.0 0.5 1.5 1 0 0 1 1 1 1 PUA domain DDHD PF02862.12 KXX83153.1 - 1.8 8.3 5.7 2.7 7.7 3.9 1.2 1 0 0 1 1 1 0 DDHD domain 2-Hacid_dh_C PF02826.14 KXX83156.1 - 9.4e-44 148.6 0.0 3.7e-43 146.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KXX83156.1 - 5.6e-05 22.6 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KXX83156.1 - 0.0022 17.8 0.3 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KXX83156.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ras PF00071.17 KXX83157.1 - 7.2e-42 142.5 0.0 1.1e-41 141.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KXX83157.1 - 7.6e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KXX83157.1 - 3.8e-11 42.5 0.0 1.5e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KXX83157.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KXX83157.1 - 0.00059 19.0 0.0 0.00077 18.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 KXX83157.1 - 0.0039 17.0 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KXX83157.1 - 0.0067 15.9 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KXX83157.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KXX83157.1 - 0.028 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KXX83157.1 - 0.028 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KXX83157.1 - 0.048 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KXX83157.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KXX83157.1 - 0.061 12.9 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KXX83157.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_2 PF00703.16 KXX83158.1 - 4.1e-13 49.7 1.3 1.8e-12 47.6 0.0 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KXX83158.1 - 8.7e-09 35.1 0.1 3.1e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KXX83158.1 - 4.9e-05 22.3 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF402 PF04167.8 KXX83158.1 - 0.049 13.4 2.3 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF402) adh_short PF00106.20 KXX83160.1 - 3.7e-25 88.7 1.4 5.2e-25 88.2 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KXX83160.1 - 2e-13 50.3 0.4 3.8e-13 49.5 0.3 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KXX83160.1 - 2.2e-07 30.9 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AraC_binding_2 PF14525.1 KXX83160.1 - 0.0036 16.8 0.5 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 AraC-binding-like domain DUF1116 PF06545.6 KXX83160.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Mur_ligase_M PF08245.7 KXX83161.1 - 8e-05 22.7 0.0 0.55 10.2 0.0 2.5 2 1 0 2 2 2 2 Mur ligase middle domain Mitofilin PF09731.4 KXX83162.1 - 5.1e-163 543.8 0.6 6.3e-163 543.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Cas_DxTHG PF09455.5 KXX83162.1 - 0.032 13.3 0.8 0.2 10.7 0.9 1.8 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family DUF1759 PF03564.10 KXX83162.1 - 0.31 10.8 2.8 0.8 9.5 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) ADH_N PF08240.7 KXX83163.1 - 2e-29 101.5 1.1 4.3e-29 100.4 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KXX83163.1 - 3e-22 78.5 0.4 6e-22 77.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX83163.1 - 9.9e-06 26.4 0.2 3.6e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KXX83163.1 - 0.0019 17.6 0.4 0.0035 16.7 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KXX83163.1 - 0.0047 17.3 0.2 0.16 12.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KXX83163.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 KXX83163.1 - 0.028 14.0 0.2 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KXX83163.1 - 0.031 12.7 1.1 0.045 12.2 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 KXX83163.1 - 0.031 14.1 0.2 0.95 9.2 0.3 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KXX83163.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mur_ligase_C PF02875.16 KXX83164.1 - 0.002 18.1 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KXX83164.1 - 0.069 13.1 0.1 0.64 10.0 0.0 2.5 1 1 0 1 1 1 0 Mur ligase middle domain DnaJ PF00226.26 KXX83165.1 - 5.1e-16 58.1 0.4 2e-15 56.2 0.2 2.1 1 0 0 1 1 1 1 DnaJ domain Kinesin PF00225.18 KXX83167.1 - 2.8e-113 378.0 0.9 2.8e-113 378.0 0.7 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KXX83167.1 - 5.8e-07 29.7 0.9 5.8e-07 29.7 0.6 5.0 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.13 KXX83167.1 - 0.00028 20.4 42.2 0.012 15.1 13.2 3.9 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain A_thal_3526 PF09713.5 KXX83167.1 - 0.073 13.2 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) COG2 PF06148.6 KXX83167.1 - 9.6 6.0 31.6 0.51 10.2 2.5 5.5 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 RRN9 PF10680.4 KXX83168.1 - 1.1e-18 66.6 0.1 1e-17 63.6 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Pex14_N PF04695.8 KXX83168.1 - 0.11 12.5 1.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2 PF00096.21 KXX83168.1 - 0.39 11.1 1.1 3.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Adaptin_N PF01602.15 KXX83169.1 - 1.6e-83 280.8 0.0 2.4e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Selenoprotein_S PF06936.6 KXX83169.1 - 0.21 11.1 8.6 0.7 9.3 5.9 1.9 1 0 0 1 1 1 0 Selenoprotein S (SelS) LCCL PF03815.14 KXX83170.1 - 7.9e-21 73.8 0.0 1.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 LCCL domain SAC3_GANP PF03399.11 KXX83171.1 - 4.6e-42 143.8 0.1 6.8e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KXX83171.1 - 0.0038 16.9 0.0 0.0091 15.7 0.0 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Methyltransf_12 PF08242.7 KXX83172.1 - 1.9e-14 53.8 0.0 6.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX83172.1 - 2.4e-11 43.9 0.0 5.2e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX83172.1 - 1.5e-10 41.2 0.0 3.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX83172.1 - 2.8e-10 40.1 0.0 4.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX83172.1 - 4.4e-08 33.6 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX83172.1 - 3.8e-07 29.4 0.0 6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KXX83172.1 - 7.1e-07 28.9 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX83172.1 - 3.3e-05 23.8 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KXX83172.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KXX83172.1 - 0.0021 17.7 0.0 0.0058 16.2 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.3 KXX83172.1 - 0.014 14.1 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 KXX83172.1 - 0.028 15.2 0.0 0.088 13.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KXX83172.1 - 0.081 11.8 0.0 7.6 5.4 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family RrnaAD PF00398.15 KXX83172.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polyketide_cyc PF03364.15 KXX83173.1 - 8.3e-34 116.3 0.0 1.3e-33 115.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KXX83173.1 - 3.5e-05 23.9 5.8 0.0051 16.9 4.1 2.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NADH_oxidored PF08040.6 KXX83173.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 MNLL subunit Glyco_hydro_43 PF04616.9 KXX83175.1 - 2.2e-16 59.8 0.0 7.1e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 EphA2_TM PF14575.1 KXX83176.1 - 0.00011 22.4 1.2 0.00038 20.7 0.0 2.4 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KXX83176.1 - 0.004 15.4 0.0 0.0098 14.1 0.0 1.6 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 KXX83176.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 DAP10 membrane protein CAP_N PF01213.14 KXX83176.1 - 9.1 5.4 16.4 0.86 8.8 4.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AMP-binding PF00501.23 KXX83177.1 - 8.4e-74 248.4 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KXX83177.1 - 5.5e-14 52.8 0.1 1.7e-13 51.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KXX83178.1 - 7.3e-40 136.7 27.7 1.9e-39 135.3 17.7 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1992 PF09350.5 KXX83179.1 - 3.2e-25 87.7 0.3 7.5e-25 86.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Fungal_trans PF04082.13 KXX83180.1 - 3e-19 68.9 0.1 5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cons_hypoth698 PF03601.9 KXX83180.1 - 0.013 14.1 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 DUF3369 PF11849.3 KXX83180.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) MMR_HSR1 PF01926.18 KXX83181.1 - 3e-07 30.3 0.0 1.1e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KXX83181.1 - 8.8e-07 28.2 0.0 2.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KXX83181.1 - 0.00014 21.9 0.2 0.0025 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 KXX83181.1 - 0.00025 20.8 1.8 0.11 12.3 0.0 2.9 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 KXX83181.1 - 0.00031 19.8 0.0 0.13 11.3 0.0 2.8 2 0 0 2 2 2 2 AIG1 family T2SE PF00437.15 KXX83181.1 - 0.0025 16.7 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KXX83181.1 - 0.0028 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KXX83181.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family Septin PF00735.13 KXX83181.1 - 0.018 14.0 0.2 0.064 12.2 0.1 1.9 1 1 0 1 1 1 0 Septin IIGP PF05049.8 KXX83181.1 - 0.023 13.5 0.0 0.057 12.2 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KXX83181.1 - 0.073 13.3 0.2 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KXX83181.1 - 0.74 10.1 4.5 0.76 10.0 0.0 2.7 2 1 0 2 2 1 0 AAA domain Ank_4 PF13637.1 KXX83182.1 - 7.1e-14 51.8 0.0 2.1e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX83182.1 - 2.1e-12 46.1 0.3 7.1e-11 41.3 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeat Ank_2 PF12796.2 KXX83182.1 - 3.9e-12 46.3 0.0 8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KXX83182.1 - 2.5e-10 39.5 0.0 4.2e-08 32.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KXX83182.1 - 8.7e-10 38.5 0.1 3.3e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF258 PF03193.11 KXX83182.1 - 8.1e-06 25.1 0.1 3.3e-05 23.1 0.0 2.0 3 0 0 3 3 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KXX83182.1 - 1e-05 25.4 0.2 3.4e-05 23.7 0.0 2.0 3 0 0 3 3 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KXX83182.1 - 2.8e-05 24.0 2.6 0.14 11.9 0.0 3.2 2 1 0 3 3 3 2 Dynamin family AAA_33 PF13671.1 KXX83182.1 - 0.00028 20.7 0.2 0.013 15.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KXX83182.1 - 0.0017 19.1 0.0 0.0037 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KXX83182.1 - 0.0022 18.1 0.1 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KXX83182.1 - 0.0025 18.2 0.1 0.0084 16.5 0.0 2.0 2 1 0 2 2 1 1 Miro-like protein Septin PF00735.13 KXX83182.1 - 0.0029 16.6 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Septin IIGP PF05049.8 KXX83182.1 - 0.0057 15.5 0.1 0.015 14.1 0.0 1.7 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 KXX83182.1 - 0.0057 16.2 0.2 0.047 13.2 0.0 2.3 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KXX83182.1 - 0.0085 15.6 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 KXX83182.1 - 0.0093 15.8 1.8 0.032 14.0 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KXX83182.1 - 0.011 15.2 0.0 0.049 13.0 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KXX83182.1 - 0.011 15.9 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain WXG100 PF06013.7 KXX83182.1 - 0.017 15.1 0.9 0.085 12.8 0.9 1.9 2 0 0 2 2 1 0 Proteins of 100 residues with WXG ABC_tran PF00005.22 KXX83182.1 - 0.018 15.3 0.4 0.14 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KXX83182.1 - 0.02 15.2 0.4 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KXX83182.1 - 0.023 13.6 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 KXX83182.1 - 0.024 14.1 0.0 0.15 11.4 0.0 2.3 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 KXX83182.1 - 0.03 13.8 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AIG1 PF04548.11 KXX83182.1 - 0.048 12.7 1.8 0.15 11.1 0.0 2.6 3 1 0 3 3 3 0 AIG1 family AAA_16 PF13191.1 KXX83182.1 - 0.052 13.5 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Spore_IV_A PF09547.5 KXX83182.1 - 0.053 12.2 0.1 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) MobB PF03205.9 KXX83182.1 - 0.062 13.0 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KXX83182.1 - 0.088 11.8 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 KXX83182.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KXX83182.1 - 0.11 11.8 0.0 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KXX83182.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 2 0 0 2 2 1 0 Archaeal ATPase GTP_EFTU PF00009.22 KXX83182.1 - 0.14 11.5 0.4 0.3 10.4 0.0 1.7 2 0 0 2 2 1 0 Elongation factor Tu GTP binding domain DivIC PF04977.10 KXX83182.1 - 0.18 11.2 2.2 0.39 10.2 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.2 KXX83183.1 - 6.1e-46 154.6 9.6 1.3e-13 51.1 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KXX83183.1 - 1.6e-38 128.6 16.8 3.2e-08 32.9 0.3 8.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 KXX83183.1 - 5e-36 119.1 7.5 2.7e-05 23.9 0.1 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KXX83183.1 - 6e-36 121.6 10.3 4.3e-07 29.9 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KXX83183.1 - 2.1e-31 107.7 3.9 9.9e-09 35.4 0.1 5.5 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KXX83183.1 - 0.083 12.3 0.1 8 5.8 0.0 3.0 3 0 0 3 3 3 0 Shigella flexneri OspC protein Acetyltransf_1 PF00583.19 KXX83185.1 - 6.1e-07 29.3 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KXX83185.1 - 2.3e-06 27.6 0.2 5.6e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KXX83185.1 - 3.4e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KXX83185.1 - 0.028 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KXX83185.1 - 0.031 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cytochrom_B561 PF03188.11 KXX83186.1 - 9.3e-07 28.7 5.9 1.6e-06 27.9 4.1 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KXX83186.1 - 3.5 7.2 7.4 0.68 9.5 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MRP-L46 PF11788.3 KXX83187.1 - 1.9e-32 112.1 0.2 3.4e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KXX83187.1 - 3.2e-07 30.0 0.1 6.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Mito_fiss_reg PF05308.6 KXX83187.1 - 3.2 7.0 7.1 6.3 6.0 4.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L37ae PF01780.14 KXX83188.1 - 2.7e-39 132.9 7.7 3e-39 132.7 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KXX83188.1 - 0.0017 18.1 3.0 0.0025 17.6 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 KXX83188.1 - 0.029 14.2 0.7 0.042 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Sgf11 PF08209.6 KXX83188.1 - 0.037 13.3 0.5 0.36 10.1 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.5 KXX83188.1 - 0.051 13.5 1.9 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KXX83188.1 - 0.079 12.7 4.8 2.2 8.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 KXX83188.1 - 0.1 12.9 1.2 1.7 9.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 KXX83188.1 - 0.11 12.2 2.8 0.2 11.3 2.0 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Tnp_zf-ribbon_2 PF13842.1 KXX83188.1 - 0.22 11.9 3.3 0.67 10.4 2.1 2.0 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon A2L_zn_ribbon PF08792.5 KXX83188.1 - 0.3 10.5 3.6 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4203 PF13886.1 KXX83189.1 - 1.4e-33 116.1 24.1 1.9e-33 115.6 16.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 KXX83190.1 - 1e-28 99.5 0.0 1.4e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Mg_trans_NIPA PF05653.9 KXX83192.1 - 8.4e-59 198.9 6.5 2e-56 191.2 1.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KXX83192.1 - 0.002 18.3 0.4 0.002 18.3 0.3 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KXX83192.1 - 0.35 9.6 4.8 0.56 8.9 0.7 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF4149 PF13664.1 KXX83192.1 - 0.58 10.2 9.7 0.41 10.7 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF4131 PF13567.1 KXX83192.1 - 6.1 6.2 12.6 50 3.2 0.2 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) EamA PF00892.15 KXX83192.1 - 8.7 6.4 25.5 0.048 13.7 2.3 3.7 3 1 1 4 4 4 0 EamA-like transporter family Mod_r PF07200.8 KXX83193.1 - 0.0099 15.7 1.3 0.011 15.6 0.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein XLF PF09302.6 KXX83193.1 - 0.07 12.8 0.2 0.077 12.7 0.2 1.1 1 0 0 1 1 1 0 XLF (XRCC4-like factor) HalX PF08663.5 KXX83193.1 - 0.073 13.0 2.9 1.9 8.5 0.1 2.2 1 1 1 2 2 2 0 HalX domain DrrA_P4M PF14860.1 KXX83193.1 - 0.16 11.7 1.0 0.86 9.3 0.1 1.8 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF3129 PF11327.3 KXX83194.1 - 1.4e-61 207.5 6.6 1.8e-61 207.2 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) ADH_zinc_N PF00107.21 KXX83195.1 - 4e-22 78.1 0.1 6.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX83195.1 - 1.2e-07 32.6 0.0 2.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3197 PF11432.3 KXX83195.1 - 0.11 12.5 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) Zn_clus PF00172.13 KXX83196.1 - 2.7e-09 36.8 6.9 2.7e-09 36.8 4.8 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEMT PF04191.8 KXX83197.1 - 1.5e-56 189.0 10.5 2e-35 121.1 1.4 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase FSH1 PF03959.8 KXX83198.1 - 1.5e-33 116.0 0.0 4.5e-33 114.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) TSSC4 PF15264.1 KXX83198.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Abhydrolase_2 PF02230.11 KXX83198.1 - 0.47 9.8 3.6 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 KXX83199.1 - 1.2e-31 109.8 0.0 3e-30 105.2 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KXX83199.1 - 2.2e-08 34.2 0.1 4.3e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KXX83199.1 - 0.00026 20.4 0.6 0.003 17.0 0.3 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KXX83199.1 - 0.0037 17.0 0.0 0.037 13.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX83199.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KXX83200.1 - 7.6e-40 136.7 55.1 8.1e-40 136.6 32.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX83200.1 - 9e-13 47.2 12.5 1.3e-12 46.7 8.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX83200.1 - 0.0029 16.2 15.6 0.0029 16.2 10.8 3.8 2 2 3 5 5 5 2 Sugar (and other) transporter GFA PF04828.9 KXX83201.1 - 3.7e-10 39.5 0.1 5.9e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme WCCH PF03716.9 KXX83201.1 - 0.11 11.9 2.7 0.26 10.8 1.9 1.6 1 0 0 1 1 1 0 WCCH motif DUF2269 PF10027.4 KXX83202.1 - 0.025 14.3 0.2 0.025 14.3 0.2 3.2 4 1 0 4 4 4 0 Predicted integral membrane protein (DUF2269) Dynactin_p62 PF05502.8 KXX83202.1 - 0.34 9.6 0.5 0.47 9.1 0.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family Rxt3 PF08642.5 KXX83203.1 - 6.9e-30 103.6 0.0 6.9e-30 103.6 0.0 3.2 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KXX83203.1 - 7.3e-07 29.0 0.0 6e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 LCCL domain Pro-kuma_activ PF09286.6 KXX83204.1 - 2.7e-14 53.4 0.0 5.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KXX83204.1 - 0.00092 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Adeno_E4 PF05385.6 KXX83205.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein GPI-anchored PF10342.4 KXX83206.1 - 2.9e-16 59.7 0.3 2.9e-16 59.7 0.2 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pyrophosphatase PF00719.14 KXX83208.1 - 4.9e-50 169.0 0.1 6.8e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sugar_tr PF00083.19 KXX83209.1 - 9.1e-113 377.1 21.3 1.1e-112 376.9 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KXX83209.1 - 9.4e-23 80.4 23.7 9.4e-23 80.4 16.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Utp12 PF04003.7 KXX83210.1 - 1.8e-22 79.3 0.0 2.6e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Mak16 PF04874.9 KXX83210.1 - 0.041 13.9 0.3 0.041 13.9 0.2 3.6 3 1 0 3 3 3 0 Mak16 protein C-terminal region Nop14 PF04147.7 KXX83210.1 - 0.3 8.9 27.2 0.3 8.9 0.1 2.1 2 0 0 2 2 2 0 Nop14-like family Zn_clus PF00172.13 KXX83211.1 - 0.0021 17.9 11.4 0.0042 16.9 0.9 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KXX83211.1 - 0.07 11.9 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CDC45 PF02724.9 KXX83213.1 - 5.5 4.8 12.4 9 4.1 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein PHD PF00628.24 KXX83214.1 - 7.9e-10 38.2 6.0 7.9e-10 38.2 4.2 2.8 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KXX83214.1 - 2.4e-08 33.6 3.0 2.4e-08 33.6 2.1 4.1 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KXX83214.1 - 1.6e-05 24.8 15.6 9.9e-05 22.3 4.2 3.4 2 1 0 2 2 2 1 RING-H2 zinc finger PHD_2 PF13831.1 KXX83214.1 - 0.00014 21.1 2.3 0.00032 19.9 1.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 KXX83214.1 - 0.00017 21.2 1.8 0.00017 21.2 1.2 3.5 5 0 0 5 5 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KXX83214.1 - 0.00025 20.6 1.2 0.00025 20.6 0.8 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KXX83214.1 - 0.00038 20.4 1.9 0.00038 20.4 1.3 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 KXX83214.1 - 0.0012 18.1 1.0 0.0041 16.4 0.7 1.9 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-Apc11 PF12861.2 KXX83214.1 - 0.0012 18.6 1.1 0.0012 18.6 0.8 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KXX83214.1 - 0.0039 16.7 4.5 0.0039 16.7 3.1 3.7 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KXX83214.1 - 0.55 10.0 10.9 0.066 12.9 1.0 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF1644 PF07800.7 KXX83214.1 - 1.1 9.0 8.8 4.4 7.1 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) zf-RING_UBOX PF13445.1 KXX83214.1 - 9 6.1 8.2 1.4 8.6 0.3 3.2 2 1 1 3 3 3 0 RING-type zinc-finger MFS_1 PF07690.11 KXX83215.1 - 3.2e-22 78.7 36.5 3.2e-22 78.7 25.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX83215.1 - 3.5e-08 32.1 2.2 3.5e-08 32.1 1.5 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF46 PF01864.12 KXX83215.1 - 0.017 14.9 0.4 0.068 13.0 0.3 2.0 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 Saccharop_dh PF03435.13 KXX83216.1 - 1.4e-18 67.0 0.0 8.8e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KXX83216.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PH_10 PF15411.1 KXX83218.1 - 3.6e-28 98.0 0.3 5.9e-28 97.3 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KXX83218.1 - 3.4e-09 36.5 0.0 1.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KXX83218.1 - 1.3e-07 31.2 6.2 2.4e-07 30.4 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KXX83218.1 - 1.1e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KXX83218.1 - 0.0011 18.6 5.7 0.0019 17.8 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KXX83218.1 - 0.0021 17.7 2.7 0.0036 16.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KXX83218.1 - 0.0022 18.0 1.4 0.0046 17.0 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KXX83218.1 - 0.04 13.9 5.2 0.073 13.1 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KXX83218.1 - 0.087 12.5 5.6 0.16 11.6 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 KXX83218.1 - 0.097 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger DUF1147 PF06615.6 KXX83218.1 - 0.14 12.0 0.4 0.39 10.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 KXX83218.1 - 1.1 9.2 4.5 2.1 8.4 3.1 1.5 1 0 0 1 1 1 0 RING-like domain DUF2217 PF10265.4 KXX83218.1 - 3.5 6.2 4.8 5.9 5.5 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Acyl_transf_3 PF01757.17 KXX83219.1 - 1.7e-30 106.0 22.2 3.1e-30 105.1 15.4 1.5 1 1 0 1 1 1 1 Acyltransferase family Med8 PF10232.4 KXX83221.1 - 8e-25 87.6 5.3 1.3e-24 86.9 3.6 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 GHMP_kinases_C PF08544.8 KXX83221.1 - 0.088 13.0 3.5 0.18 12.0 0.7 2.5 2 1 0 2 2 2 0 GHMP kinases C terminal DUF2457 PF10446.4 KXX83221.1 - 0.16 10.6 7.3 0.26 9.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KXX83221.1 - 0.44 8.4 5.3 0.5 8.2 3.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KXX83221.1 - 0.45 8.4 2.7 0.62 8.0 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KXX83221.1 - 0.55 9.7 8.2 1 8.9 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KXX83221.1 - 1.6 9.0 12.3 1.1 9.4 5.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KXX83221.1 - 3.7 6.7 5.7 6.5 5.9 3.9 1.3 1 0 0 1 1 1 0 NOA36 protein Sulfatase PF00884.18 KXX83222.1 - 6e-53 180.0 0.0 1e-52 179.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KXX83222.1 - 4.2e-25 87.3 2.2 8.5e-24 83.1 0.5 2.5 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal PQ-loop PF04193.9 KXX83222.1 - 7.4e-23 79.8 6.0 2.6e-13 49.3 1.4 2.4 2 0 0 2 2 2 2 PQ loop repeat Phosphodiest PF01663.17 KXX83222.1 - 1.1e-08 34.8 0.1 0.00049 19.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KXX83222.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Herpes_capsid PF06112.6 KXX83222.1 - 0.63 10.0 5.3 33 4.4 0.0 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Chromo PF00385.19 KXX83223.1 - 5.6e-14 51.5 0.3 5.6e-14 51.5 0.2 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VirC1 PF07015.6 KXX83223.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein Ric8 PF10165.4 KXX83225.1 - 1.7e-106 356.7 0.0 3.6e-65 220.5 0.0 2.1 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 KXX83226.1 - 1.2e-139 465.4 0.9 1.6e-139 464.9 0.6 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.15 KXX83227.1 - 1.7e-31 109.4 0.0 4.4e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.11 KXX83228.1 - 5.3e-195 647.9 0.0 6e-195 647.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family p450 PF00067.17 KXX83229.1 - 4e-57 193.7 0.0 5.9e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.9 KXX83230.1 - 2.1e-11 43.6 9.9 1.6e-07 31.1 0.1 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KXX83230.1 - 0.023 14.2 0.3 0.023 14.2 0.2 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 KXX83230.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal DUF1857 PF08982.6 KXX83231.1 - 5.9e-24 84.3 0.0 6.7e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) AMP-binding PF00501.23 KXX83232.1 - 1.1e-80 271.1 0.0 1.6e-80 270.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KXX83232.1 - 2.1e-48 164.7 0.0 2.6e-24 85.5 0.0 3.1 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.20 KXX83232.1 - 7.2e-13 48.5 0.1 4.9e-07 29.9 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KXX83232.1 - 5e-06 27.3 0.5 1.5e-05 25.8 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KXX83232.1 - 0.00022 21.4 0.0 0.0013 19.0 0.0 2.2 2 0 0 2 2 2 1 HxxPF-repeated domain Methyltransf_2 PF00891.13 KXX83233.1 - 1.2e-40 139.2 0.0 1.7e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KXX83233.1 - 0.00043 20.0 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX83233.1 - 0.0012 19.3 0.0 0.01 16.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX83233.1 - 0.029 14.8 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KXX83234.1 - 3.4e-23 82.6 0.1 4.1e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KXX83234.1 - 3.2e-06 27.0 4.2 0.073 12.8 0.3 3.2 2 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KXX83234.1 - 4.3e-05 22.5 0.7 0.0028 16.5 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KXX83234.1 - 0.00012 22.2 0.1 0.11 12.4 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KXX83234.1 - 0.00014 20.5 0.1 0.025 13.0 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 KXX83234.1 - 0.0018 17.4 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KXX83234.1 - 0.0023 16.9 1.2 0.026 13.4 0.2 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KXX83234.1 - 0.0026 16.7 3.4 0.0029 16.5 0.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX83234.1 - 0.0043 17.0 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KXX83234.1 - 0.016 14.3 0.1 0.05 12.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 KXX83234.1 - 0.051 12.1 0.4 0.4 9.2 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase CbiG_N PF11760.3 KXX83234.1 - 0.087 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal GIDA PF01134.17 KXX83234.1 - 0.088 11.6 2.1 0.85 8.4 0.4 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KXX83234.1 - 0.09 11.6 0.1 7.8 5.3 0.2 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Aminotran_1_2 PF00155.16 KXX83235.1 - 6.9e-31 107.5 0.0 1.5e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GST_C PF00043.20 KXX83236.1 - 3.7e-09 36.4 0.0 6.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KXX83236.1 - 5e-07 29.5 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KXX83236.1 - 5.1e-06 26.8 0.2 7.9e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KXX83236.1 - 0.001 19.2 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KXX83236.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.1 KXX83237.1 - 1.4e-19 70.3 0.0 1.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX83237.1 - 4.6e-12 46.4 0.1 6.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX83237.1 - 3.2e-11 43.5 0.0 5.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX83237.1 - 8.2e-11 41.7 0.0 1.6e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KXX83237.1 - 2.6e-10 40.6 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX83237.1 - 1.2e-06 28.5 0.1 2.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX83237.1 - 5.9e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KXX83237.1 - 1.5e-05 24.2 0.0 0.00013 21.1 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KXX83237.1 - 0.00013 21.4 0.0 0.00093 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_19 PF04672.7 KXX83237.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase MFS_1 PF07690.11 KXX83238.1 - 1.1e-34 119.7 55.0 2e-34 118.8 36.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KXX83238.1 - 1.5e-13 49.8 13.8 2.5e-13 49.0 9.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KXX83238.1 - 9.6e-05 21.1 16.5 9.6e-05 21.1 11.5 3.7 3 2 1 4 4 4 2 Sugar (and other) transporter F-box-like PF12937.2 KXX83240.1 - 0.006 16.2 1.5 0.013 15.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX83240.1 - 0.056 13.1 0.8 0.16 11.7 0.5 1.7 1 0 0 1 1 1 0 F-box domain Carb_bind PF10645.4 KXX83241.1 - 3.2e-15 55.6 9.3 3.2e-15 55.6 6.5 2.2 2 0 0 2 2 2 1 Carbohydrate binding Ni_hydr_CYTB PF01292.15 KXX83242.1 - 0.19 11.0 7.0 0.29 10.4 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 ABC2_membrane_4 PF12730.2 KXX83242.1 - 0.51 9.4 16.9 0.76 8.8 11.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EI24 PF07264.6 KXX83242.1 - 4 6.7 17.6 1.1 8.6 6.3 2.1 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Zn_clus PF00172.13 KXX83243.1 - 0.11 12.4 6.9 0.24 11.3 4.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 KXX83244.1 - 1.1e-28 100.5 0.0 1.4e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KXX83244.1 - 0.00061 18.7 0.0 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 CsiD Pkinase_Tyr PF07714.12 KXX83245.1 - 9.5e-07 28.1 0.0 2.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KXX83245.1 - 5.8e-06 25.6 0.0 2.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain DUF1996 PF09362.5 KXX83247.1 - 1.1e-89 300.1 1.4 1.3e-89 299.9 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.6 KXX83248.1 - 1.1e-05 25.5 0.1 0.00095 19.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RGS PF00615.14 KXX83249.1 - 2.5e-11 43.7 0.0 2.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.22 KXX83250.1 - 2.6e-05 24.4 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 PCI domain Rox3 PF08633.5 KXX83250.1 - 1.5 9.1 5.2 0.5 10.6 0.4 2.0 2 0 0 2 2 2 0 Rox3 mediator complex subunit UQ_con PF00179.21 KXX83251.1 - 4.6e-48 162.2 0.0 6e-48 161.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX83251.1 - 6.8e-06 25.8 0.0 9.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX83251.1 - 0.00099 18.9 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KXX83251.1 - 0.0048 16.5 0.0 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 UEV domain Ribosomal_L31e PF01198.14 KXX83252.1 - 3.8e-38 129.0 1.7 4.9e-38 128.6 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e adh_short PF00106.20 KXX83253.1 - 2.5e-36 125.1 0.2 5.1e-35 120.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX83253.1 - 2e-14 53.9 0.0 2.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX83253.1 - 2.5e-12 46.8 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KXX83253.1 - 0.0019 17.1 0.1 0.004 16.1 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KXX83253.1 - 0.003 17.2 0.1 0.0087 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KXX83253.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Suf PF05843.9 KXX83254.1 - 1.6e-11 44.4 9.7 0.0067 16.2 2.5 5.8 3 2 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KXX83254.1 - 3.9e-11 42.7 0.3 2.8 7.9 0.0 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KXX83254.1 - 5.7e-07 29.6 17.8 2.1 9.1 0.0 10.4 10 2 2 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 KXX83254.1 - 2.9e-05 23.6 9.0 1.2 8.8 0.0 6.7 8 1 0 8 8 8 2 TPR repeat NRDE-2 PF08424.5 KXX83254.1 - 5.4e-05 22.2 11.9 0.061 12.1 0.1 6.0 2 2 4 6 6 6 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 KXX83254.1 - 6.6e-05 22.0 1.2 6.6e-05 22.0 0.8 4.1 3 2 2 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KXX83254.1 - 0.00027 20.7 10.8 1.2 8.8 0.1 6.4 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 RPN7 PF10602.4 KXX83254.1 - 0.0006 19.2 1.3 0.0028 17.0 0.1 2.7 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 KXX83254.1 - 0.0014 18.2 4.3 0.75 9.7 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KXX83254.1 - 0.0057 17.3 14.4 0.076 13.7 0.0 6.7 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KXX83254.1 - 0.071 13.0 22.8 4.3 7.4 0.0 7.9 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 KXX83254.1 - 0.077 13.2 4.8 6.9 7.1 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.1 KXX83254.1 - 0.085 13.1 0.0 1.5 9.3 0.0 3.2 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 KXX83254.1 - 5.3 7.7 7.2 65 4.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat ThiF PF00899.16 KXX83255.1 - 4.4e-11 42.7 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.13 KXX83256.1 - 4.2e-27 94.6 0.1 6.8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KXX83256.1 - 3.1e-07 30.2 12.6 5.5e-07 29.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 KXX83257.1 - 9.6e-56 188.3 0.2 2e-55 187.3 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX83257.1 - 4.2e-44 151.5 3.2 1.1e-43 150.1 2.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KXX83257.1 - 9.6e-43 144.1 0.7 5.5e-11 42.4 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KXX83257.1 - 1.7e-13 51.1 0.0 5.1e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX83257.1 - 1.3e-05 24.9 0.3 0.00045 19.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4038 PF13204.1 KXX83257.1 - 0.4 9.9 0.0 0.67 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) UBA_4 PF14555.1 KXX83258.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain p450 PF00067.17 KXX83259.1 - 8.1e-48 163.0 0.0 8.3e-47 159.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KXX83260.1 - 1.5e-63 214.6 0.0 2.7e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KXX83260.1 - 7.7e-52 175.5 1.2 2.9e-51 173.7 0.8 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KXX83260.1 - 2e-51 175.2 0.0 3.4e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KXX83260.1 - 2.9e-47 161.2 0.0 4.7e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KXX83260.1 - 8.3e-39 133.1 1.9 3.7e-38 131.0 1.3 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KXX83260.1 - 3.2e-35 120.5 0.1 1.1e-34 118.8 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KXX83260.1 - 2.5e-17 62.6 0.0 8.9e-17 60.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KXX83260.1 - 4.4e-13 50.2 0.0 4.6e-12 46.9 0.0 2.9 3 0 0 3 3 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KXX83260.1 - 6.1e-07 29.6 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KXX83260.1 - 4.5e-05 23.1 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 KXX83260.1 - 0.00018 21.9 0.0 0.024 15.1 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain ACP_syn_III PF08545.5 KXX83260.1 - 0.011 15.3 0.9 0.055 13.1 0.3 2.6 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_18 PF12847.2 KXX83260.1 - 0.023 15.2 0.0 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Thiolase_N PF00108.18 KXX83260.1 - 0.037 13.0 0.1 0.076 11.9 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 KXX83260.1 - 0.063 12.8 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KXX83260.1 - 0.074 13.4 0.0 1.6 9.1 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 KXX83260.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KXX83260.1 - 0.12 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 KXX83261.1 - 3.1e-16 59.9 0.0 4.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX83261.1 - 3.6e-13 49.4 0.0 5.4e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KXX83261.1 - 7.4e-11 41.1 0.0 1.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KXX83261.1 - 5.2e-05 22.5 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 KXX83261.1 - 0.0011 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal p450 PF00067.17 KXX83262.1 - 1e-40 139.6 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1674 PF07896.7 KXX83263.1 - 2.2e-17 62.9 2.3 4.6e-17 61.9 1.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) PAT1 PF09770.4 KXX83263.1 - 0.42 8.7 11.4 0.46 8.6 7.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSA-2c PF12238.3 KXX83263.1 - 0.61 9.7 7.0 0.81 9.3 4.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase PF00069.20 KXX83264.1 - 3e-32 111.7 0.0 7.5e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX83264.1 - 1.2e-12 47.5 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KXX83264.1 - 0.023 14.4 0.1 0.098 12.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KXX83264.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AMP-binding PF00501.23 KXX83265.1 - 1.1e-80 271.0 0.0 1.7e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TroA PF01297.12 KXX83265.1 - 0.099 11.8 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Periplasmic solute binding protein family FAD_binding_4 PF01565.18 KXX83266.1 - 1.2e-17 63.6 1.9 2.4e-17 62.6 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KXX83266.1 - 1.2e-12 47.4 0.2 2.3e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KXX83266.1 - 0.0083 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.17 KXX83267.1 - 1.4e-64 218.3 0.0 1.7e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bromodomain PF00439.20 KXX83269.1 - 1.4e-38 130.7 0.2 2e-23 82.1 0.1 3.1 3 0 0 3 3 3 2 Bromodomain DUF155 PF02582.9 KXX83270.1 - 5.1e-56 189.3 0.2 9.7e-56 188.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CDC37_N PF03234.9 KXX83271.1 - 2.3e-60 203.9 5.3 2.3e-60 203.9 3.7 2.2 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KXX83271.1 - 6.8e-47 159.1 0.1 1.9e-46 157.7 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KXX83271.1 - 3.9e-24 84.3 1.4 3.9e-24 84.3 1.0 2.5 2 1 0 2 2 2 1 Cdc37 C terminal domain Prominin PF05478.6 KXX83271.1 - 0.14 9.7 0.9 0.21 9.0 0.6 1.2 1 0 0 1 1 1 0 Prominin Cpn60_TCP1 PF00118.19 KXX83272.1 - 2e-137 458.7 8.6 2.2e-137 458.6 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 KXX83272.1 - 0.0055 16.3 0.7 0.025 14.2 0.3 2.2 2 1 0 2 2 2 1 PKC-activated protein phosphatase-1 inhibitor Y_phosphatase3 PF13350.1 KXX83272.1 - 0.037 14.2 0.3 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family HMG_box PF00505.14 KXX83273.1 - 1.9e-10 40.8 0.8 3.9e-10 39.8 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KXX83273.1 - 6.9e-06 26.3 2.3 6.9e-06 26.3 1.6 2.2 2 1 1 3 3 3 1 HMG-box domain SlyX PF04102.7 KXX83273.1 - 0.86 10.0 4.2 9.7 6.6 0.7 3.3 2 1 1 3 3 3 0 SlyX DUF3535 PF12054.3 KXX83274.1 - 3e-152 507.2 0.6 7.4e-152 506.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KXX83274.1 - 2.5e-73 246.5 0.0 3.7e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KXX83274.1 - 7.2e-14 50.5 8.3 0.011 15.7 0.0 9.6 9 0 0 9 9 9 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KXX83274.1 - 7.4e-06 26.2 0.4 0.63 10.4 0.0 4.0 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KXX83274.1 - 0.00021 21.5 19.3 0.01 16.1 0.0 7.8 8 2 0 8 8 8 1 HEAT repeats HEAT_EZ PF13513.1 KXX83274.1 - 0.0096 16.3 15.1 12 6.5 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat Clr5 PF14420.1 KXX83275.1 - 2.2e-20 72.2 0.8 5.1e-20 71.1 0.6 1.7 1 0 0 1 1 1 1 Clr5 domain Amidohydro_2 PF04909.9 KXX83276.1 - 1.8e-39 135.9 0.4 2.2e-39 135.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KXX83276.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 TatD related DNase SMC_N PF02463.14 KXX83277.1 - 3.6e-56 189.8 35.1 7.9e-56 188.7 24.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KXX83277.1 - 3.4e-26 91.5 0.0 2.3e-25 88.9 0.0 2.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KXX83277.1 - 1.6e-14 54.5 4.7 1.6e-06 28.3 0.0 3.0 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KXX83277.1 - 9.5e-14 52.2 27.2 9.5e-14 52.2 18.9 7.7 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.1 KXX83277.1 - 1.6e-05 24.1 35.1 0.00095 18.3 9.5 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KXX83277.1 - 0.00049 19.5 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KXX83277.1 - 0.33 11.2 0.0 0.33 11.2 0.0 6.5 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 KXX83277.1 - 1.2 8.1 22.5 0.088 11.9 1.3 4.8 4 1 1 5 5 5 0 Reovirus sigma C capsid protein peroxidase PF00141.18 KXX83278.1 - 1.4e-20 73.8 0.1 2.3e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Peroxidase HET PF06985.6 KXX83278.1 - 4.6e-05 23.6 0.1 9.8e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KXX83279.1 - 3.4e-39 134.6 0.0 4.4e-39 134.2 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Noc2 PF03715.8 KXX83280.1 - 2.2e-121 404.3 0.2 5.3e-121 403.0 0.0 1.7 2 0 0 2 2 2 1 Noc2p family DUF726 PF05277.7 KXX83281.1 - 3.2e-112 374.8 0.3 4.4e-112 374.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 KXX83281.1 - 1.2e-05 25.7 0.0 3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KXX83281.1 - 0.00019 21.4 0.5 0.00067 19.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KXX83281.1 - 0.00071 19.3 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KXX83281.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 KXX83281.1 - 0.0087 15.6 0.0 0.036 13.6 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Cutinase PF01083.17 KXX83281.1 - 0.048 13.3 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase Gly-zipper_OmpA PF13436.1 KXX83281.1 - 4.2 7.0 15.2 2.2 7.9 2.9 3.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain GFA PF04828.9 KXX83282.1 - 1.7e-16 59.8 4.3 2.9e-16 59.1 3.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KXX83282.1 - 0.099 12.3 0.2 0.099 12.3 0.1 2.6 2 1 0 2 2 2 0 Nudix N-terminal Cys_rich_CWC PF14375.1 KXX83282.1 - 7.6 6.5 11.1 0.16 11.9 2.3 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC Gln-synt_C PF00120.19 KXX83283.1 - 4.3e-57 193.2 0.0 5.4e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KXX83283.1 - 1.4e-20 72.6 0.0 2.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RNase_P_p30 PF01876.11 KXX83285.1 - 1.5e-41 141.1 0.0 2.4e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF155 PF02582.9 KXX83286.1 - 2.4e-60 203.3 0.1 4.5e-60 202.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 KXX83286.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain PTCB-BRCT PF12738.2 KXX83287.1 - 0.11 12.3 0.1 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain AT_hook PF02178.14 KXX83287.1 - 0.13 11.9 16.3 0.56 10.0 1.7 4.1 3 0 0 3 3 3 0 AT hook motif DUF2404 PF10296.4 KXX83288.1 - 0.00028 20.9 0.0 0.0016 18.5 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) CDC45 PF02724.9 KXX83288.1 - 0.41 8.6 1.4 2.6 5.9 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein VPS28 PF03997.7 KXX83289.1 - 1e-54 185.0 0.1 1.2e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KXX83289.1 - 0.2 11.5 3.4 0.57 10.0 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein G CD52 PF15116.1 KXX83290.1 - 0.73 9.6 3.3 3 7.7 0.1 2.8 2 0 0 2 2 2 0 CAMPATH-1 antigen Pkinase PF00069.20 KXX83292.1 - 5.7e-18 65.0 0.0 8.9e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX83292.1 - 5.2e-06 25.7 0.0 6.2e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KXX83292.1 - 0.091 11.5 0.0 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KXX83293.1 - 1.8e-19 69.9 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX83293.1 - 0.0057 15.7 0.0 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2642 PF10842.3 KXX83294.1 - 0.14 11.6 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) HET PF06985.6 KXX83295.1 - 3.6e-21 75.7 0.0 6.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 KXX83296.1 - 3.4e-43 147.8 0.0 2.8e-37 128.3 0.0 2.8 3 0 0 3 3 3 2 Cytochrome P450 PAF-AH_p_II PF03403.8 KXX83297.1 - 0.13 10.4 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ank_2 PF12796.2 KXX83298.1 - 1.4e-06 28.5 0.0 5.3e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KXX83298.1 - 5.7e-06 26.6 0.0 0.078 13.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KXX83298.1 - 0.00017 21.1 0.3 0.96 9.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KXX83298.1 - 0.0012 18.8 0.2 1.3 9.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KXX83299.1 - 9.2e-29 99.6 1.8 5.9e-14 52.1 0.3 3.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KXX83299.1 - 1e-19 69.2 15.0 9e-06 25.2 0.1 6.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 KXX83299.1 - 3.1e-18 64.0 5.1 4e-05 23.4 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KXX83299.1 - 2e-17 63.2 3.1 4.6e-06 27.0 0.1 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KXX83299.1 - 6.8e-15 54.7 4.4 1.9e-06 27.9 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Peptidase_M28 PF04389.12 KXX83300.1 - 2.9e-34 118.3 0.0 5.5e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KXX83300.1 - 1.9e-15 56.3 0.2 4.1e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KXX83300.1 - 3e-05 23.6 0.0 7.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HET PF06985.6 KXX83301.1 - 0.0053 16.9 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M13_N PF05649.8 KXX83302.1 - 5.2e-55 187.0 0.4 8.2e-55 186.4 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KXX83302.1 - 6.3e-51 172.4 0.5 2.7e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M4 PF01447.13 KXX83302.1 - 0.68 10.0 4.7 6.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Thermolysin metallopeptidase, catalytic domain CLN3 PF02487.12 KXX83303.1 - 1.5e-97 326.9 23.4 5.8e-54 183.4 0.2 3.0 2 1 0 2 2 2 2 CLN3 protein DUF413 PF04219.7 KXX83304.1 - 0.13 12.0 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF DUF1741 PF08427.5 KXX83307.1 - 2e-87 292.5 0.0 4.6e-87 291.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 KXX83308.1 - 1.4e-18 66.8 0.0 1.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ndc1_Nup PF09531.5 KXX83308.1 - 3.4 5.9 6.1 3.8 5.8 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MgsA_C PF12002.3 KXX83309.1 - 4.6e-61 205.3 0.0 1.5e-60 203.7 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KXX83309.1 - 1.1e-12 48.3 0.0 2.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KXX83309.1 - 1.2e-10 40.8 0.0 1.5e-09 37.2 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KXX83309.1 - 8.3e-07 28.6 0.1 3.3e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KXX83309.1 - 3.9e-05 23.7 0.9 0.00035 20.7 0.3 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KXX83309.1 - 0.00011 21.9 0.2 0.0087 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KXX83309.1 - 0.00011 21.8 0.1 0.00052 19.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KXX83309.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KXX83309.1 - 0.00037 19.7 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KXX83309.1 - 0.00051 20.0 5.7 0.0081 16.1 0.0 3.3 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KXX83309.1 - 0.00078 18.2 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KXX83309.1 - 0.0017 19.1 0.0 0.004 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KXX83309.1 - 0.0029 17.1 0.1 0.078 12.5 0.0 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KXX83309.1 - 0.0031 16.5 0.0 0.0069 15.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 KXX83309.1 - 0.017 14.9 0.2 3.8 7.3 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 KXX83309.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.1 KXX83309.1 - 0.081 12.8 0.5 0.19 11.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KXX83309.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KXX83309.1 - 0.1 12.8 0.1 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KXX83309.1 - 0.14 11.5 2.4 7.8 5.8 0.1 3.1 2 1 1 3 3 3 0 AAA-like domain CPT PF07931.7 KXX83309.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Annexin PF00191.15 KXX83310.1 - 9.1e-67 220.8 6.3 5.2e-21 74.3 0.0 4.3 4 0 0 4 4 4 4 Annexin Cpn60_TCP1 PF00118.19 KXX83312.1 - 5.6e-147 490.2 3.5 6.4e-147 490.0 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 KXX83312.1 - 0.17 11.7 2.5 37 4.2 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain GTP_EFTU PF00009.22 KXX83313.1 - 2.1e-47 161.0 0.0 3.6e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KXX83313.1 - 2.4e-20 72.4 0.3 4.9e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 KXX83313.1 - 9e-07 28.8 0.0 4.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KXX83313.1 - 9.1e-07 28.9 0.1 2.1e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KXX83313.1 - 1.6e-05 24.8 0.0 4.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KXX83313.1 - 0.00016 22.1 0.1 0.0035 17.8 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KXX83313.1 - 0.015 14.5 0.0 3.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.16 KXX83313.1 - 0.026 13.7 0.0 6.3 6.0 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family DUF444 PF04285.7 KXX83313.1 - 0.053 12.1 0.0 0.093 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Gtr1_RagA PF04670.7 KXX83313.1 - 0.14 11.2 0.0 0.39 9.8 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region EmrE PF13536.1 KXX83314.1 - 0.0027 17.8 5.9 0.0027 17.8 4.1 2.0 1 1 1 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KXX83314.1 - 0.012 15.4 3.7 0.018 14.8 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 EamA PF00892.15 KXX83314.1 - 0.018 15.1 13.7 0.051 13.6 9.4 1.8 1 1 0 1 1 1 0 EamA-like transporter family RskA PF10099.4 KXX83314.1 - 0.033 13.9 1.1 0.72 9.5 0.1 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ca_hom_mod PF14798.1 KXX83314.1 - 0.096 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator TFIIA_gamma_C PF02751.9 KXX83315.1 - 8.3e-26 89.5 0.8 1.2e-25 89.0 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KXX83315.1 - 1.6e-24 85.2 0.2 2.3e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MoCF_biosynth PF00994.19 KXX83316.1 - 9.4e-57 190.4 2.0 2e-32 111.5 0.1 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KXX83316.1 - 4.6e-32 110.5 5.6 7.8e-32 109.8 3.9 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KXX83316.1 - 5.5e-17 61.4 0.2 2.9e-16 59.1 0.0 2.4 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) 7TMR-HDED PF07697.6 KXX83316.1 - 0.15 11.7 0.5 0.26 11.0 0.4 1.3 1 0 0 1 1 1 0 7TM-HD extracellular SelP_N PF04592.9 KXX83316.1 - 6.6 6.0 16.8 10 5.4 11.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAS20 PF02064.10 KXX83317.1 - 2.3e-17 63.0 1.1 6.3e-17 61.6 0.8 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor TipAS PF07739.8 KXX83317.1 - 0.018 15.3 2.1 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4381 PF14316.1 KXX83317.1 - 0.035 14.2 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RskA PF10099.4 KXX83317.1 - 0.044 13.5 0.7 0.06 13.0 0.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.5 KXX83317.1 - 0.058 13.0 2.2 0.086 12.4 1.6 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4230 PF14014.1 KXX83317.1 - 0.41 10.5 2.5 1.2 8.9 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Wyosine_form PF08608.7 KXX83318.1 - 1.1e-24 86.2 0.0 2.8e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 KXX83318.1 - 5.4e-23 81.9 0.1 1.2e-22 80.8 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 KXX83318.1 - 7.2e-09 35.7 0.0 5.4e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin p450 PF00067.17 KXX83319.1 - 3.4e-18 65.4 0.0 1.5e-10 40.1 0.0 2.4 2 1 1 3 3 3 2 Cytochrome P450 Metallophos PF00149.23 KXX83320.1 - 3e-44 150.8 1.0 3.8e-44 150.4 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 KXX83321.1 - 5.7e-17 61.3 2.0 5.7e-17 61.3 1.4 2.8 4 0 0 4 4 4 1 Vps51/Vps67 Laminin_B PF00052.13 KXX83321.1 - 0.019 14.5 1.5 0.037 13.6 0.2 2.2 2 1 1 3 3 3 0 Laminin B (Domain IV) COG2 PF06148.6 KXX83321.1 - 0.031 14.1 3.2 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dam1 PF08653.5 KXX83321.1 - 0.16 11.7 1.1 12 5.7 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 Sec5 PF15469.1 KXX83321.1 - 0.57 9.8 5.9 0.34 10.6 0.2 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 V_ATPase_I PF01496.14 KXX83321.1 - 1.1 7.0 9.0 0.64 7.8 0.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KXX83321.1 - 1.7 7.6 11.8 0.048 12.7 0.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Mto2_bdg PF12808.2 KXX83321.1 - 8.4 6.5 10.5 1 9.5 1.5 3.2 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ARID PF01388.16 KXX83322.1 - 4.5e-20 71.2 0.0 1.2e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HEAT_2 PF13646.1 KXX83322.1 - 0.024 14.9 0.2 0.098 12.9 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats V-ATPase_H_N PF03224.9 KXX83322.1 - 0.027 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H TFIIA PF03153.8 KXX83322.1 - 7.3 6.3 21.6 3.7 7.3 6.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SAP PF02037.22 KXX83323.1 - 5.8e-13 47.9 0.2 9.8e-13 47.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 KXX83323.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX83323.1 - 0.18 11.8 0.0 0.81 9.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Packaging_FI PF14000.1 KXX83323.1 - 2.2 8.4 9.1 0.053 13.7 0.5 2.5 2 1 0 2 2 2 0 DNA packaging protein FI GATase PF00117.23 KXX83324.1 - 5.6e-47 159.6 0.0 7.7e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KXX83324.1 - 1.6e-46 157.0 0.0 2.4e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 KXX83324.1 - 4.5e-07 29.5 0.2 6.6e-05 22.4 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 F-box-like PF12937.2 KXX83325.1 - 1.9e-08 33.8 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KXX83325.1 - 1.5e-06 27.7 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 KXX83325.1 - 0.00054 19.3 13.0 0.025 14.1 1.6 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 KXX83326.1 - 0.24 11.3 20.5 3.1 7.7 1.3 3.8 4 0 0 4 4 4 0 FYVE-type zinc finger Auto_anti-p27 PF06677.7 KXX83326.1 - 1.2 8.9 11.2 0.62 9.8 0.1 3.4 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sar8_2 PF03058.9 KXX83326.1 - 2 8.7 11.8 0.5 10.7 1.5 2.8 2 1 0 2 2 2 0 Sar8.2 family Asp PF00026.18 KXX83327.1 - 8.7e-09 35.0 0.2 2.6e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AJAP1_PANP_C PF15298.1 KXX83327.1 - 0.026 14.4 0.2 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Ist1 PF03398.9 KXX83328.1 - 1.1e-67 226.5 2.5 1.5e-67 226.1 1.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway OHCU_decarbox PF09349.5 KXX83328.1 - 0.046 14.0 0.3 0.19 11.9 0.0 2.0 1 1 1 2 2 2 0 OHCU decarboxylase zf-CCHC_2 PF13696.1 KXX83329.1 - 2.6e-05 23.6 4.3 0.004 16.6 0.7 2.8 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.3 KXX83329.1 - 0.25 11.2 4.9 0.23 11.3 0.7 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Clat_adaptor_s PF01217.15 KXX83330.1 - 4e-57 191.9 2.0 4.4e-57 191.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Serinc PF03348.10 KXX83331.1 - 9.4e-175 581.4 5.2 1.1e-174 581.1 3.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CitMHS PF03600.11 KXX83331.1 - 0.015 13.8 8.7 0.055 12.0 5.8 2.0 2 0 0 2 2 2 0 Citrate transporter Cys_Met_Meta_PP PF01053.15 KXX83332.1 - 1.6e-138 461.2 0.0 1.8e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KXX83332.1 - 9.5e-07 27.8 0.0 1.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KXX83332.1 - 4e-06 26.0 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KXX83332.1 - 2.2e-05 23.6 0.1 4.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 KXX83332.1 - 2.9e-05 22.5 0.1 7.2e-05 21.2 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KXX83332.1 - 0.00079 18.2 0.1 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KXX83332.1 - 0.012 14.7 0.1 0.028 13.5 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase AAA PF00004.24 KXX83333.1 - 1.6e-37 128.6 0.0 2.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KXX83333.1 - 2.1e-06 27.6 0.0 5.1e-06 26.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KXX83333.1 - 3.2e-06 27.3 0.1 0.00044 20.3 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.1 KXX83333.1 - 5e-06 26.6 1.9 0.00012 22.1 0.0 3.0 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.9 KXX83333.1 - 1e-05 25.2 0.1 9.9e-05 22.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KXX83333.1 - 1.1e-05 26.2 0.1 4e-05 24.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KXX83333.1 - 2.8e-05 23.2 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KXX83333.1 - 3.9e-05 23.6 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KXX83333.1 - 0.00023 20.6 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KXX83333.1 - 0.00051 19.2 0.2 0.0014 17.8 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KXX83333.1 - 0.00053 20.0 0.0 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 KXX83333.1 - 0.00068 19.5 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KXX83333.1 - 0.0011 18.3 1.5 0.03 13.7 0.1 2.8 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 KXX83333.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KXX83333.1 - 0.0017 17.4 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KXX83333.1 - 0.002 17.8 0.3 0.014 15.0 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KXX83333.1 - 0.0025 17.8 0.1 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KXX83333.1 - 0.0026 17.4 0.0 0.0077 15.9 0.0 1.8 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 KXX83333.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KXX83333.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KXX83333.1 - 0.019 13.8 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KXX83333.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain Oxidored_nitro PF00148.14 KXX83333.1 - 0.028 13.0 0.0 0.34 9.4 0.0 2.1 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase Parvo_NS1 PF01057.12 KXX83333.1 - 0.028 13.3 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KXX83333.1 - 0.03 14.6 0.0 0.091 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.10 KXX83333.1 - 0.037 12.7 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 KXX83333.1 - 0.063 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KXX83333.1 - 0.068 12.8 0.0 0.22 11.1 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 KXX83333.1 - 0.068 12.6 0.0 0.3 10.4 0.0 2.1 2 1 0 2 2 1 0 Guanylate kinase SKI PF01202.17 KXX83333.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.8 KXX83333.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 KXX83333.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KXX83333.1 - 0.14 11.2 0.0 0.54 9.3 0.0 1.9 1 1 1 2 2 2 0 KaiC Bac_DnaA PF00308.13 KXX83333.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 KXX83333.1 - 0.18 10.6 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 KXX83333.1 - 0.19 10.6 0.2 0.58 9.0 0.0 1.7 1 1 1 2 2 2 0 KAP family P-loop domain Csm1 PF12539.3 KXX83334.1 - 2e-25 89.0 0.0 4.9e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 BBP1_C PF15272.1 KXX83334.1 - 0.0001 21.8 0.6 0.00021 20.9 0.4 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Spc7 PF08317.6 KXX83334.1 - 0.0028 16.3 9.1 0.0048 15.6 6.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KXX83334.1 - 0.01 15.0 1.3 0.015 14.4 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 KXX83334.1 - 0.043 13.7 11.7 0.044 13.6 6.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KXX83334.1 - 0.33 8.7 1.0 0.5 8.1 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 KXX83334.1 - 0.54 9.7 10.0 0.97 8.9 6.4 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KXX83334.1 - 2 6.7 17.4 0.02 13.4 5.1 2.0 2 0 0 2 2 2 0 AAA domain DUF4615 PF15393.1 KXX83334.1 - 2.2 8.5 9.8 0.082 13.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) FimP PF09766.4 KXX83334.1 - 2.6 7.0 11.5 0.25 10.3 4.7 1.7 2 0 0 2 2 2 0 Fms-interacting protein Fib_alpha PF08702.5 KXX83334.1 - 3.5 7.7 7.1 10 6.2 4.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TFIID-18kDa PF02269.11 KXX83335.1 - 7.9e-31 105.7 2.1 7.5e-30 102.5 0.1 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 KXX83335.1 - 0.051 12.7 0.6 0.078 12.1 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RNA_GG_bind PF10258.4 KXX83335.1 - 0.083 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain Zn_clus PF00172.13 KXX83336.1 - 1.1e-09 38.0 9.9 2e-09 37.1 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KXX83336.1 - 1e-06 27.6 2.0 1.5e-06 27.0 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.14 KXX83337.1 - 1.4e-20 73.3 0.0 1.7e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KXX83337.1 - 6.5e-11 42.0 1.9 1.4e-10 41.0 1.3 1.5 1 0 0 1 1 1 1 GAT domain Jnk-SapK_ap_N PF09744.4 KXX83337.1 - 0.64 9.9 5.9 1.2 9.1 4.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 zf-CHY PF05495.7 KXX83338.1 - 2.5e-16 59.5 25.9 4.8e-15 55.4 10.0 3.3 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 KXX83338.1 - 8.1e-05 21.6 0.3 8.1e-05 21.6 0.2 2.4 3 0 0 3 3 3 1 Mu-like prophage protein Com RWD PF05773.17 KXX83338.1 - 0.0018 18.1 0.2 0.026 14.4 0.0 2.5 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 KXX83338.1 - 0.15 11.0 3.0 0.38 9.7 2.0 1.6 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HECT PF00632.20 KXX83339.1 - 3.6e-66 223.4 0.0 5.4e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 KXX83340.1 - 2.1e-33 114.4 8.0 1.1e-27 96.1 0.5 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KXX83340.1 - 1.4e-06 28.2 20.7 1.9e-05 24.6 2.6 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KXX83340.1 - 1.7e-06 27.9 2.3 1.7e-06 27.9 1.6 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KXX83340.1 - 0.0028 17.8 20.7 0.27 11.6 0.9 4.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-DBF PF07535.7 KXX83340.1 - 0.018 14.7 0.3 0.018 14.7 0.2 3.4 3 0 0 3 3 3 0 DBF zinc finger AKAP95 PF04988.7 KXX83340.1 - 0.54 10.0 4.0 15 5.3 0.2 2.9 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF3753 PF12575.3 KXX83341.1 - 1.2 8.9 6.3 0.77 9.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) CorA PF01544.13 KXX83342.1 - 5.5e-10 38.7 0.3 8e-10 38.2 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein tRNA-synt_2 PF00152.15 KXX83343.1 - 4.5e-85 285.3 0.9 6.1e-85 284.9 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KXX83343.1 - 9.8e-12 44.5 0.1 1.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KXX83343.1 - 1.1e-09 37.8 0.1 9.5e-05 21.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ArfGap PF01412.13 KXX83344.1 - 1.6e-40 137.5 0.4 2.5e-40 136.8 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UCH PF00443.24 KXX83345.1 - 6.1e-38 130.4 0.0 8.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KXX83345.1 - 1.2e-09 38.1 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KXX83345.1 - 0.0009 19.5 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-C3HC PF07967.8 KXX83346.1 - 1e-37 128.8 0.0 6.3e-37 126.3 0.0 2.0 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.5 KXX83346.1 - 3.2e-15 55.7 0.4 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 KXX83346.1 - 0.00027 21.3 0.1 0.004 17.5 0.1 2.3 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-RING_4 PF14570.1 KXX83347.1 - 2.6e-19 68.5 12.0 4.3e-19 67.8 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KXX83347.1 - 2.9e-09 36.4 0.1 1.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KXX83347.1 - 4.8e-05 22.9 9.9 8.3e-05 22.1 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KXX83347.1 - 9.6e-05 22.2 0.0 0.00036 20.4 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX83347.1 - 0.00061 19.5 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KXX83347.1 - 0.00094 18.4 2.8 0.00094 18.4 1.9 3.8 4 0 0 4 4 3 1 Rtf2 RING-finger Nup35_RRM_2 PF14605.1 KXX83347.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.20 KXX83347.1 - 0.088 12.4 10.1 0.18 11.4 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 KXX83347.1 - 0.21 10.9 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated FYVE PF01363.16 KXX83347.1 - 0.28 11.1 6.6 0.61 10.0 4.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.6 KXX83347.1 - 0.35 10.5 7.0 0.76 9.5 4.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.1 KXX83347.1 - 1.1 9.4 10.8 2 8.5 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KXX83347.1 - 1.7 8.5 16.9 0.27 11.1 4.9 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger FAD_binding_1 PF00667.15 KXX83348.1 - 5.7e-64 215.5 0.0 1.2e-63 214.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KXX83348.1 - 4.2e-11 43.3 0.0 1.5e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KXX83348.1 - 5.3e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KXX83348.1 - 0.00088 19.2 0.6 0.0052 16.7 0.1 2.5 3 0 0 3 3 3 1 Transketolase, C-terminal domain E1-E2_ATPase PF00122.15 KXX83349.1 - 3.1e-51 173.6 0.0 6.8e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KXX83349.1 - 7.9e-39 134.2 1.0 1.6e-38 133.2 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KXX83349.1 - 9.1e-37 125.0 1.2 8.3e-12 45.0 0.1 4.8 5 0 0 5 5 5 4 Heavy-metal-associated domain HAD PF12710.2 KXX83349.1 - 5.2e-17 62.6 0.0 1.3e-16 61.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KXX83349.1 - 0.00018 21.1 0.0 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KXX83349.1 - 0.0026 18.0 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SIP1 PF04938.7 KXX83349.1 - 0.076 12.3 0.0 0.23 10.7 0.0 1.8 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) TIR_2 PF13676.1 KXX83349.1 - 0.085 13.0 0.2 29 4.9 0.0 3.2 4 0 0 4 4 4 0 TIR domain Diphtheria_C PF02763.9 KXX83350.1 - 0.067 12.6 1.4 0.088 12.2 1.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Fe-ADH PF00465.14 KXX83351.1 - 1.7e-104 349.4 0.0 2.1e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KXX83351.1 - 3.1e-15 56.1 0.0 2.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KXX83351.1 - 0.00016 21.1 0.1 0.00024 20.5 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Formyl_trans_N PF00551.14 KXX83351.1 - 0.13 11.8 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Formyl transferase APH PF01636.18 KXX83352.1 - 2.3e-10 40.6 0.0 3.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sec3_C PF09763.4 KXX83353.1 - 1.2e-253 843.3 0.0 1.6e-253 842.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KXX83353.1 - 2.3e-30 104.3 0.0 4.1e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KXX83353.1 - 0.0061 16.6 2.1 0.017 15.2 0.0 2.7 3 0 0 3 3 3 1 Sec3 exocyst complex subunit EST1_DNA_bind PF10373.4 KXX83353.1 - 0.013 14.7 0.1 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Vps52 PF04129.7 KXX83353.1 - 0.083 11.3 4.5 0.12 10.9 0.2 2.3 2 0 0 2 2 2 0 Vps52 / Sac2 family HECT PF00632.20 KXX83354.1 - 1.5e-83 280.5 0.0 2.5e-83 279.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KXX83354.1 - 0.0061 16.5 0.8 1 9.6 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 KXX83354.1 - 0.011 15.0 0.3 0.05 12.9 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.18 KXX83354.1 - 0.046 13.5 4.7 4.1 7.3 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.6 KXX83354.1 - 0.22 9.6 9.1 0.41 8.7 6.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ESCRT-II PF05871.7 KXX83356.1 - 3.7e-33 114.3 0.0 1.5e-26 92.9 0.0 2.4 2 0 0 2 2 2 2 ESCRT-II complex subunit Glyco_hydro_7 PF00840.15 KXX83357.1 - 1.4e-210 699.1 23.8 1.6e-210 698.9 16.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fapy_DNA_glyco PF01149.19 KXX83358.1 - 3.4e-24 85.4 0.0 5.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KXX83358.1 - 8.5e-21 73.5 0.0 1.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KXX83358.1 - 0.013 14.0 0.0 0.037 12.5 0.0 1.7 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) ATP-synt_C PF00137.16 KXX83359.1 - 1.4e-26 92.2 28.8 6.4e-17 61.2 4.6 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Cation_efflux PF01545.16 KXX83359.1 - 4.5 6.2 15.9 0.025 13.6 1.5 2.4 1 1 1 2 2 2 0 Cation efflux family Oxidored_q2 PF00420.19 KXX83359.1 - 5.3 6.6 11.1 37 3.9 6.2 2.8 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L HNH_2 PF13391.1 KXX83360.1 - 6.8e-07 28.9 0.0 2.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 HNH endonuclease DUF1510 PF07423.6 KXX83360.1 - 0.17 11.2 23.6 0.75 9.1 13.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) POX PF07526.6 KXX83360.1 - 1.9 8.7 10.7 28 4.9 0.0 3.2 3 0 0 3 3 3 0 Associated with HOX HSP70 PF00012.15 KXX83363.1 - 2.2e-269 894.4 14.4 2.5e-269 894.2 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KXX83363.1 - 1.4e-16 60.0 2.4 9.3e-15 54.0 1.6 2.2 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KXX83363.1 - 0.0089 15.1 0.2 0.0089 15.1 0.2 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase SpoIIAA-like PF11964.3 KXX83363.1 - 0.042 14.1 1.4 3.4 7.9 0.1 2.9 2 0 0 2 2 2 0 SpoIIAA-like FtsA PF14450.1 KXX83363.1 - 1.2 9.0 9.3 4.4 7.1 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA COesterase PF00135.23 KXX83366.1 - 3.3e-86 290.1 0.0 5.3e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KXX83366.1 - 6.3e-06 25.9 0.5 4.4e-05 23.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KXX83366.1 - 0.16 11.1 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family His_Phos_1 PF00300.17 KXX83368.1 - 1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ABC_tran PF00005.22 KXX83369.1 - 2.2e-46 157.5 0.2 7.9e-25 87.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KXX83369.1 - 2.3e-22 79.5 40.4 2.7e-17 62.8 12.0 2.7 3 0 0 3 3 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KXX83369.1 - 2.8e-22 80.0 0.9 1.9e-05 24.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 KXX83369.1 - 1.7e-09 37.0 2.7 0.00084 18.8 0.3 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 KXX83369.1 - 6.8e-08 32.0 3.9 0.035 13.3 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KXX83369.1 - 1.5e-05 25.3 3.2 0.031 14.5 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KXX83369.1 - 0.00051 20.0 1.2 1 9.3 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KXX83369.1 - 0.00084 18.5 0.3 0.75 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KXX83369.1 - 0.0039 16.6 0.9 2.5 7.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 KXX83369.1 - 0.0084 15.7 1.6 1.5 8.3 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KXX83369.1 - 0.016 15.1 0.6 21 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KXX83369.1 - 0.024 13.7 0.0 4.6 6.1 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 KXX83369.1 - 0.056 13.5 0.3 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KXX83369.1 - 0.068 12.6 1.5 6.2 6.2 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 KXX83369.1 - 0.07 13.0 0.5 27 4.7 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KXX83369.1 - 0.13 11.6 2.1 4.1 6.7 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KXX83369.1 - 0.21 11.0 0.8 1.1 8.7 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 KXX83369.1 - 0.49 9.0 0.0 2.1 6.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 KXX83369.1 - 0.53 10.2 2.4 25 4.7 0.4 2.8 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 KXX83369.1 - 0.58 8.5 0.3 6 5.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KXX83369.1 - 0.61 8.8 5.1 4.1 6.0 0.1 3.2 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 KXX83369.1 - 1.3 8.8 3.6 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPR_10 PF13374.1 KXX83370.1 - 2.9e-69 227.2 0.0 8.3e-12 44.6 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KXX83370.1 - 8.7e-63 208.2 0.5 1.3e-15 57.0 0.0 5.2 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KXX83370.1 - 9.5e-20 68.7 5.1 0.0023 17.6 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KXX83370.1 - 3.8e-12 45.2 1.6 1.7 8.3 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KXX83370.1 - 1.2e-10 40.6 0.1 1.4 9.2 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KXX83370.1 - 1.6e-10 40.0 4.9 1 9.4 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.9 KXX83370.1 - 2.6e-10 39.7 1.1 0.13 12.8 0.2 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat RelA_SpoT PF04607.12 KXX83370.1 - 1.6e-09 37.8 0.0 4.3e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins TPR_11 PF13414.1 KXX83370.1 - 1.8e-09 37.0 0.3 0.0051 16.4 0.0 4.1 1 1 4 5 5 5 5 TPR repeat TPR_19 PF14559.1 KXX83370.1 - 8.5e-08 32.4 0.2 0.73 10.2 0.0 5.7 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KXX83370.1 - 2.3e-07 31.2 0.0 0.17 12.6 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KXX83370.1 - 7.7e-07 29.2 2.2 19 6.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat NB-ARC PF00931.17 KXX83370.1 - 7.8e-07 28.2 0.2 2.2e-05 23.4 0.0 2.9 2 2 1 3 3 3 1 NB-ARC domain AAA_22 PF13401.1 KXX83370.1 - 2.6e-06 27.5 0.0 1.7e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KXX83370.1 - 1.4e-05 24.5 2.5 8.5 6.4 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KXX83370.1 - 3.1e-05 24.0 0.0 0.43 10.7 0.0 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KXX83370.1 - 0.08 13.4 5.2 3e+02 2.2 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Pex14_N PF04695.8 KXX83371.1 - 1.1e-37 129.1 0.0 1.1e-37 129.1 0.0 2.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 KXX83371.1 - 6.5e-06 26.3 0.5 6.5e-06 26.3 0.4 1.7 2 0 0 2 2 1 1 Zinc finger-containing protein CR6_interact PF10147.4 KXX83371.1 - 0.00021 20.6 0.2 0.00029 20.2 0.1 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 IncA PF04156.9 KXX83371.1 - 0.00034 20.2 0.6 0.00058 19.5 0.4 1.3 1 0 0 1 1 1 1 IncA protein ERM PF00769.14 KXX83371.1 - 0.007 15.9 9.4 0.013 15.0 6.5 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF3584 PF12128.3 KXX83371.1 - 0.0084 13.5 10.8 0.011 13.0 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 KXX83371.1 - 0.011 15.5 5.6 0.46 10.3 0.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 KXX83371.1 - 0.013 14.0 1.3 0.018 13.5 0.9 1.2 1 0 0 1 1 1 0 AAA domain LEM PF03020.10 KXX83371.1 - 0.037 13.4 0.2 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 LEM domain DUF848 PF05852.6 KXX83371.1 - 0.05 13.4 7.8 0.089 12.6 5.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) tRNA-synt_His PF13393.1 KXX83371.1 - 0.089 11.8 1.0 0.47 9.4 0.1 2.0 1 1 1 2 2 2 0 Histidyl-tRNA synthetase ADIP PF11559.3 KXX83371.1 - 0.13 12.1 8.8 0.31 10.9 6.0 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Dor1 PF04124.7 KXX83371.1 - 0.17 10.3 3.7 0.23 9.8 2.6 1.2 1 0 0 1 1 1 0 Dor1-like family PilJ PF13675.1 KXX83371.1 - 0.2 12.0 4.6 1.6 9.0 3.1 2.3 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 KXX83371.1 - 0.22 10.6 1.3 0.33 10.0 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Glu-tRNAGln PF02686.10 KXX83371.1 - 0.28 11.0 3.2 4.6 7.1 1.9 2.8 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Prominin PF05478.6 KXX83371.1 - 0.43 8.0 1.8 0.59 7.6 1.2 1.2 1 0 0 1 1 1 0 Prominin FUSC PF04632.7 KXX83371.1 - 0.51 8.6 5.1 0.7 8.2 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TRADD_N PF09034.5 KXX83371.1 - 0.59 10.1 2.6 1.2 9.1 1.8 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain Spc7 PF08317.6 KXX83371.1 - 0.91 8.1 6.1 1.4 7.5 4.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF148 PF02520.12 KXX83371.1 - 1.6 8.5 5.2 0.76 9.5 1.9 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF148 TBPIP PF07106.8 KXX83371.1 - 1.9 8.0 5.9 0.99 8.9 2.0 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 KXX83371.1 - 2.1 7.9 8.8 5.3 6.5 1.5 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 SYCE1 PF15233.1 KXX83371.1 - 2.4 8.1 8.8 0.43 10.4 3.7 1.4 2 0 0 2 2 1 0 Synaptonemal complex central element protein 1 Syntaxin PF00804.20 KXX83371.1 - 2.5 8.3 8.6 22 5.2 5.9 2.2 1 1 0 1 1 1 0 Syntaxin DUF1451 PF07295.6 KXX83371.1 - 3.2 7.4 6.5 5.8 6.6 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Atg14 PF10186.4 KXX83371.1 - 3.3 6.5 8.0 4.4 6.1 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 KXX83371.1 - 3.7 7.4 8.5 16 5.4 4.4 2.3 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Abhydrolase_3 PF07859.8 KXX83372.1 - 4.6e-41 140.7 2.2 1.5e-40 139.0 1.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KXX83372.1 - 7.4e-05 22.5 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KXX83372.1 - 0.0036 15.9 1.1 0.062 11.9 0.7 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Cyt-b5 PF00173.23 KXX83373.1 - 1.6e-25 88.6 0.2 2.1e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.21 KXX83374.1 - 3.8e-22 77.2 24.4 1.5e-05 25.0 1.4 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KXX83374.1 - 2.3e-19 68.6 26.2 3e-07 30.3 0.7 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KXX83374.1 - 7.8e-16 57.1 25.2 0.00028 21.0 2.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KXX83374.1 - 1.6e-05 24.8 4.1 4 7.6 0.0 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KXX83374.1 - 0.0059 16.4 12.9 0.45 10.4 0.3 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 KXX83374.1 - 0.0068 16.5 8.2 4.8 7.5 0.4 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type DUF2072 PF09845.4 KXX83374.1 - 0.14 12.1 0.5 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) XPA_N PF01286.13 KXX83374.1 - 0.19 11.4 0.2 0.19 11.4 0.1 3.0 4 0 0 4 4 4 0 XPA protein N-terminal C1_1 PF00130.17 KXX83374.1 - 0.35 10.6 4.3 0.56 9.9 1.1 2.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 KXX83374.1 - 0.42 10.6 10.1 6.1 6.8 1.1 3.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-TRAF PF02176.13 KXX83374.1 - 0.5 10.7 8.3 2.6 8.4 0.4 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger LIM PF00412.17 KXX83374.1 - 2.8 8.0 5.8 29 4.8 0.0 3.0 2 1 1 3 3 3 0 LIM domain HeLo PF14479.1 KXX83376.1 - 6e-11 42.4 0.0 8.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation DNA_pol3_tau_5 PF12170.3 KXX83376.1 - 0.076 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha Pox_MCEL PF03291.11 KXX83377.1 - 1.3e-65 221.4 0.0 1e-45 156.0 0.0 2.6 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 KXX83377.1 - 4.6e-09 36.6 0.0 0.0039 17.6 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KXX83377.1 - 5.4e-07 30.1 0.6 4e-06 27.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX83377.1 - 1e-06 29.1 0.0 3.4e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX83377.1 - 2.7e-06 27.2 0.0 6.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX83377.1 - 3.4e-06 27.3 0.0 1.1e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KXX83377.1 - 1.3e-05 24.8 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Raftlin PF15250.1 KXX83377.1 - 0.00049 18.7 0.6 0.00049 18.7 0.4 1.8 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.12 KXX83377.1 - 0.00083 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 KXX83377.1 - 0.029 14.3 0.3 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF4355 PF14265.1 KXX83377.1 - 0.61 10.0 16.9 0.93 9.4 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DDRGK PF09756.4 KXX83377.1 - 6.4 6.1 16.5 1.3 8.3 0.4 2.6 3 0 0 3 3 3 0 DDRGK domain EF_assoc_2 PF08356.7 KXX83378.1 - 5.2e-35 119.0 0.0 1.1e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 KXX83378.1 - 1.2e-34 119.3 0.0 3.1e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 KXX83378.1 - 6.5e-34 115.0 0.4 1.5e-33 113.9 0.1 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 KXX83378.1 - 1.4e-24 86.3 0.0 6.4e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KXX83378.1 - 6.9e-09 35.6 0.0 6.2e-05 22.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KXX83378.1 - 5.1e-07 29.1 0.0 0.0011 18.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KXX83378.1 - 1.1e-06 28.8 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_7 PF13499.1 KXX83378.1 - 1.1e-06 28.6 0.9 0.026 14.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 KXX83378.1 - 6.9e-06 25.9 0.1 0.17 11.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 KXX83378.1 - 1.2e-05 25.4 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KXX83378.1 - 2.2e-05 23.6 0.0 0.06 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 EF-hand_1 PF00036.27 KXX83378.1 - 2.2e-05 23.3 2.7 0.016 14.5 0.4 2.7 2 0 0 2 2 2 2 EF hand ABC_tran PF00005.22 KXX83378.1 - 3.4e-05 24.1 0.0 0.09 13.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter EF-hand_6 PF13405.1 KXX83378.1 - 0.0003 20.4 3.0 0.19 11.6 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain DUF815 PF05673.8 KXX83378.1 - 0.0005 19.0 0.0 0.5 9.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.1 KXX83378.1 - 0.00058 19.5 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KXX83378.1 - 0.00061 19.2 0.0 0.99 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KXX83378.1 - 0.00086 19.4 0.0 0.34 11.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.22 KXX83378.1 - 0.0011 18.4 0.0 2.2 7.6 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 KXX83378.1 - 0.0012 18.5 0.0 0.2 11.3 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KXX83378.1 - 0.0031 17.3 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KXX83378.1 - 0.0084 16.4 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KXX83378.1 - 0.0098 15.5 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KXX83378.1 - 0.013 14.6 0.0 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 KXX83378.1 - 0.014 14.4 0.0 0.54 9.2 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_28 PF13521.1 KXX83378.1 - 0.015 15.2 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 KXX83378.1 - 0.016 14.7 2.4 4.3 7.0 0.4 2.6 2 0 0 2 2 2 0 EF-hand domain pair IIGP PF05049.8 KXX83378.1 - 0.021 13.6 0.1 1.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) EF-hand_5 PF13202.1 KXX83378.1 - 0.035 13.4 6.8 0.15 11.4 1.3 2.7 2 0 0 2 2 2 0 EF hand AAA_10 PF12846.2 KXX83378.1 - 0.067 12.6 0.0 7.2 5.9 0.0 2.5 3 0 0 3 3 2 0 AAA-like domain PRK PF00485.13 KXX83378.1 - 0.072 12.6 0.0 4.7 6.7 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 KXX83378.1 - 0.072 12.5 0.0 3.5 7.1 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KXX83378.1 - 0.076 12.9 0.3 0.26 11.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 KXX83378.1 - 0.078 12.4 0.2 7.1 6.0 0.0 3.5 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KXX83378.1 - 0.078 12.1 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SPARC_Ca_bdg PF10591.4 KXX83378.1 - 0.089 12.8 0.1 6 6.9 0.0 2.9 3 1 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA PF00004.24 KXX83378.1 - 0.11 12.7 0.1 5.7 7.1 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KXX83378.1 - 0.12 12.0 0.0 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AIG1 PF04548.11 KXX83378.1 - 0.13 11.3 0.4 2 7.4 0.2 2.4 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 KXX83378.1 - 0.13 13.0 0.0 27 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KXX83379.1 - 2.4e-22 77.9 15.1 3.8e-07 29.7 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 KXX83379.1 - 0.0072 14.2 0.0 0.0096 13.7 0.0 1.2 1 0 0 1 1 1 1 IKI3 family eIF2A PF08662.6 KXX83379.1 - 0.012 15.3 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KXX83379.1 - 0.016 14.9 2.0 2.4 7.8 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KXX83379.1 - 0.07 11.4 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arrestin_C PF02752.17 KXX83380.1 - 8.8e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KXX83380.1 - 3.7e-10 39.8 0.0 7.3e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KXX83380.1 - 0.00063 19.3 0.0 0.004 16.6 0.0 2.1 1 1 1 2 2 2 1 Arrestin_N terminal like F-actin_cap_A PF01267.12 KXX83381.1 - 5.8e-83 278.0 0.0 6.5e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Dermcidin PF15291.1 KXX83382.1 - 0.015 15.4 0.3 0.043 14.0 0.2 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Speriolin_N PF15058.1 KXX83382.1 - 0.095 12.5 3.5 0.17 11.7 2.4 1.3 1 0 0 1 1 1 0 Speriolin N terminus FAD_binding_4 PF01565.18 KXX83383.1 - 1.9e-08 33.9 0.0 5e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.19 KXX83384.1 - 1.2e-47 161.0 33.0 5.3e-25 87.6 4.5 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 KXX83384.1 - 2.6 7.4 0.0 2.6 7.4 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) CDO_I PF05995.7 KXX83385.1 - 1.8e-40 137.9 0.0 2.2e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KXX83385.1 - 0.0023 17.3 0.1 0.0032 16.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Git3 PF11710.3 KXX83386.1 - 3.1e-17 62.8 7.1 6.6e-17 61.7 4.9 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KXX83386.1 - 2.6e-09 36.6 2.6 2.8e-09 36.5 1.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KXX83386.1 - 0.011 14.5 8.0 0.022 13.6 5.6 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Herpes_gE PF02480.11 KXX83386.1 - 0.027 12.7 0.2 6.9 4.8 0.0 2.8 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E 7TM_GPCR_Srz PF10325.4 KXX83386.1 - 0.056 12.5 6.1 0.18 10.8 4.2 1.8 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz CBFD_NFYB_HMF PF00808.18 KXX83387.1 - 2.5e-11 43.4 0.1 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 KXX83388.1 - 3.9e-89 299.1 30.6 3.9e-89 299.1 21.2 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KXX83388.1 - 1.8e-13 50.0 0.4 3.3e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF754 PF05449.6 KXX83388.1 - 0.032 14.2 1.3 0.15 12.0 0.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF754) Pkinase PF00069.20 KXX83389.1 - 3.5e-24 85.3 0.0 5.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KXX83389.1 - 3.4e-13 48.9 12.9 7.4e-09 35.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 KXX83389.1 - 3.7e-12 45.2 3.6 0.0039 17.1 0.2 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 KXX83389.1 - 6.2e-06 26.4 4.8 0.19 12.0 0.1 4.0 2 1 2 4 4 4 4 HEAT repeats Pkinase_Tyr PF07714.12 KXX83389.1 - 1.6e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KXX83389.1 - 0.0011 19.4 5.0 0.0083 16.5 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.15 KXX83389.1 - 0.16 10.2 0.5 6.3 4.9 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region LRR_9 PF14580.1 KXX83390.1 - 1.6e-48 164.5 1.0 1.6e-48 164.5 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KXX83390.1 - 2.8e-11 42.7 4.1 1.6e-06 27.6 0.3 3.5 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KXX83390.1 - 4e-07 29.6 0.1 4e-07 29.6 0.1 2.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 KXX83390.1 - 8.9e-05 22.0 0.9 0.14 12.4 0.2 4.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KXX83390.1 - 0.00041 20.0 3.6 0.95 9.7 0.1 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat DUF4349 PF14257.1 KXX83390.1 - 0.0056 15.9 3.0 0.0093 15.2 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.1 KXX83390.1 - 0.075 13.1 0.3 12 6.3 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat PspB PF06667.7 KXX83390.1 - 0.099 12.5 3.0 0.42 10.5 1.1 2.6 3 0 0 3 3 3 0 Phage shock protein B UPF0128 PF03673.8 KXX83390.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) DUF3112 PF11309.3 KXX83391.1 - 6.4e-26 91.0 3.4 1.2e-25 90.1 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) SH3_9 PF14604.1 KXX83392.1 - 9.6e-08 31.4 0.2 2e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KXX83392.1 - 0.00015 21.0 0.4 0.0003 20.1 0.3 1.5 1 0 0 1 1 1 1 SH3 domain ACT PF01842.20 KXX83393.1 - 0.0019 17.6 0.0 0.0055 16.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain HLH PF00010.21 KXX83393.1 - 0.059 13.0 1.6 0.2 11.3 0.3 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain zf-C2H2 PF00096.21 KXX83394.1 - 0.0013 18.9 14.0 0.03 14.6 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KXX83394.1 - 0.024 14.9 8.1 0.036 14.4 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KXX83394.1 - 8.3 6.9 6.9 12 6.3 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain RRM_1 PF00076.17 KXX83396.1 - 3.9e-31 106.4 0.2 1.3e-14 53.5 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KXX83396.1 - 9.7e-25 86.3 0.0 4.5e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KXX83396.1 - 4.7e-08 32.7 0.0 0.0065 16.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 KXX83396.1 - 0.0028 16.2 2.7 0.0038 15.7 1.9 1.3 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DbpA PF03880.10 KXX83396.1 - 0.055 13.1 0.1 9.4 5.9 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Lin0512_fam PF09585.5 KXX83396.1 - 0.62 9.6 3.5 14 5.2 0.6 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Flavodoxin_1 PF00258.20 KXX83397.1 - 7.4e-29 100.5 0.0 1.2e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KXX83397.1 - 6.4e-26 91.1 0.0 1.4e-24 86.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KXX83397.1 - 8.6e-11 42.3 0.0 2.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 KXX83397.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain ETF PF01012.16 KXX83398.1 - 3.6e-37 127.6 0.3 4.5e-37 127.2 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 KXX83399.1 - 1.1e-32 112.3 0.0 1.9e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ATP_bind_1 PF03029.12 KXX83400.1 - 1.5e-75 253.7 0.0 2e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KXX83400.1 - 0.00068 18.5 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 KXX83400.1 - 0.023 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KXX83400.1 - 0.033 13.3 0.1 0.088 11.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KXX83400.1 - 0.12 12.6 0.1 17 5.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KXX83400.1 - 0.14 11.5 0.2 0.6 9.4 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain CbiA PF01656.18 KXX83400.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 KXX83400.1 - 0.15 11.4 0.1 13 5.1 0.1 2.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain GIT_SHD PF08518.6 KXX83400.1 - 0.23 10.8 3.2 0.35 10.2 1.2 2.0 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT AAA_17 PF13207.1 KXX83400.1 - 1.5 9.6 6.3 0.39 11.5 0.3 2.6 2 2 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.14 KXX83401.1 - 2.5e-34 117.4 0.0 3.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family CM_2 PF01817.16 KXX83402.1 - 1.3e-06 28.3 0.0 0.0014 18.7 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 KXX83403.1 - 1.2e-38 129.5 8.7 5.4e-10 38.7 0.2 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 KXX83403.1 - 1.3e-06 26.8 7.5 0.042 11.9 0.0 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 APG6 PF04111.7 KXX83403.1 - 0.27 10.2 2.8 0.4 9.6 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 KXX83403.1 - 0.3 10.2 2.1 0.61 9.2 1.4 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 WD40 PF00400.27 KXX83405.1 - 2.3e-24 84.3 0.2 6.2e-06 25.8 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat GATA PF00320.22 KXX83407.1 - 1.9e-17 62.3 3.0 4.1e-17 61.2 2.1 1.6 1 0 0 1 1 1 1 GATA zinc finger RRN7 PF11781.3 KXX83407.1 - 0.0055 16.1 0.5 0.0098 15.3 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KXX83407.1 - 0.01 15.3 0.8 0.024 14.1 0.3 1.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger TF_Zn_Ribbon PF08271.7 KXX83407.1 - 0.065 12.5 0.4 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KXX83407.1 - 0.092 11.9 0.3 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 KXX83407.1 - 0.14 11.9 1.3 0.38 10.6 0.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_3 PF13878.1 KXX83407.1 - 0.54 9.8 3.0 4.2 7.0 0.3 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Prim_Zn_Ribbon PF08273.7 KXX83407.1 - 0.92 9.6 3.1 2.7 8.1 2.1 1.7 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Peptidase_S8 PF00082.17 KXX83407.1 - 4.2 6.4 7.2 16 4.5 5.0 1.8 1 1 0 1 1 1 0 Subtilase family COPI_assoc PF08507.5 KXX83408.1 - 7.2e-46 155.2 5.6 7.9e-46 155.1 3.9 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 KXX83408.1 - 0.45 9.6 5.3 0.3 10.1 0.8 2.0 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Neurensin PF14927.1 KXX83408.1 - 5.7 6.3 7.1 22 4.4 5.0 2.2 1 1 0 1 1 1 0 Neurensin DUF3784 PF12650.2 KXX83408.1 - 6.7 6.7 9.8 0.35 10.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF308 PF03729.8 KXX83408.1 - 8.9 6.3 19.8 1.7 8.6 4.0 2.8 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) BCIP PF13862.1 KXX83409.1 - 1.3e-63 214.0 0.1 1.7e-63 213.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PTCB-BRCT PF12738.2 KXX83410.1 - 1.8e-31 107.7 1.0 3.8e-19 68.2 0.2 4.7 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.21 KXX83410.1 - 6.8e-25 87.0 0.0 2.2e-07 30.9 0.0 5.6 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain Ndc80_HEC PF03801.8 KXX83412.1 - 3.3e-43 146.8 0.3 6.9e-27 93.8 0.0 2.5 1 1 1 2 2 2 2 HEC/Ndc80p family WASH_WAHD PF11945.3 KXX83412.1 - 0.0016 17.8 3.1 0.0016 17.8 2.2 1.7 2 0 0 2 2 2 1 WAHD domain of WASH complex 2OG-Fe_Oxy_2 PF10014.4 KXX83412.1 - 0.0017 17.7 0.2 0.1 11.9 0.0 2.7 3 0 0 3 3 3 1 2OG-Fe dioxygenase DUF4391 PF14335.1 KXX83412.1 - 0.0026 17.1 6.6 0.0026 17.1 4.6 3.3 2 1 0 2 2 1 1 Domain of unknown function (DUF4391) DUF1664 PF07889.7 KXX83412.1 - 0.0058 16.4 0.6 0.0058 16.4 0.4 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) Anth_Ig PF05587.8 KXX83412.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Anthrax receptor extracellular domain V_ATPase_I PF01496.14 KXX83412.1 - 0.33 8.7 29.8 0.18 9.6 5.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 KXX83412.1 - 0.54 10.0 56.2 0.3 10.9 11.4 4.4 2 2 2 4 4 4 0 Tropomyosin like NPV_P10 PF05531.7 KXX83412.1 - 1.9 8.7 10.6 10 6.4 1.5 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KXX83412.1 - 2.5 5.3 41.1 1.3 6.2 10.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 KXX83412.1 - 4.8 5.7 36.2 0.53 8.9 6.4 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.9 KXX83412.1 - 6.4 6.6 37.7 1.2 9.0 7.6 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) zf-Nse PF11789.3 KXX83413.1 - 3.1e-19 68.2 1.9 5.6e-19 67.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KXX83413.1 - 0.00033 20.2 1.0 0.00068 19.3 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KXX83413.1 - 0.0012 18.3 1.0 0.002 17.5 0.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 KXX83413.1 - 0.002 17.8 0.6 0.0033 17.2 0.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KXX83413.1 - 0.026 14.3 0.1 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KXX83413.1 - 0.044 13.6 0.1 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 KXX83413.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 KXX83413.1 - 0.081 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KXX83413.1 - 0.13 12.1 1.2 0.21 11.4 0.8 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KXX83413.1 - 0.23 11.1 2.3 0.37 10.4 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pap_E4 PF02711.9 KXX83413.1 - 0.95 10.3 4.5 1.8 9.4 0.4 2.7 2 0 0 2 2 2 0 E4 protein Cwf_Cwc_15 PF04889.7 KXX83413.1 - 1.2 8.7 11.7 2.5 7.7 2.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cupin_2 PF07883.6 KXX83414.1 - 1.4e-14 53.3 0.1 2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KXX83414.1 - 7.4e-07 28.6 0.0 8.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KXX83414.1 - 8.1e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 KXX83414.1 - 0.00028 20.5 0.1 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KXX83414.1 - 0.00099 18.4 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.3 KXX83414.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like MannoseP_isomer PF01050.13 KXX83414.1 - 0.027 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HgmA PF04209.8 KXX83414.1 - 0.081 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase SUN PF03856.8 KXX83415.1 - 1e-77 260.8 9.1 1.4e-77 260.3 6.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Clr2 PF10383.4 KXX83416.1 - 3.2e-21 75.7 0.0 5.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Thiolase_N PF00108.18 KXX83417.1 - 1.7e-90 302.5 0.3 2.7e-90 301.9 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KXX83417.1 - 7.1e-38 128.8 1.9 1.4e-37 127.8 0.8 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KXX83417.1 - 0.00017 21.1 0.5 0.00073 19.0 0.3 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MutL_C PF08676.6 KXX83418.1 - 1.6e-22 79.6 0.4 4.5e-22 78.1 0.1 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KXX83418.1 - 3.3e-17 62.0 0.0 8.7e-17 60.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KXX83418.1 - 1.3e-12 47.5 0.0 1.3e-12 47.5 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KXX83418.1 - 3.6e-10 39.5 0.0 1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.8 KXX83419.1 - 2.2e-88 295.6 0.0 3.2e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KXX83419.1 - 2e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KXX83419.1 - 5.3e-05 23.1 0.1 9.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KXX83419.1 - 0.0051 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KXX83419.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 KXX83419.1 - 0.12 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family adh_short PF00106.20 KXX83420.1 - 1.2e-20 74.0 0.0 1.6e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX83420.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX83420.1 - 1.3e-05 24.9 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KXX83420.1 - 0.039 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KXX83420.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 KXX83420.1 - 0.12 11.4 0.0 1.3 8.1 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Mito_carr PF00153.22 KXX83421.1 - 0.086 12.5 1.7 2.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial carrier protein Pkinase PF00069.20 KXX83422.1 - 2.4e-05 23.6 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KXX83422.1 - 0.085 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TerB PF05099.8 KXX83423.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB Kinesin PF00225.18 KXX83425.1 - 3.1e-113 377.8 0.5 7.4e-113 376.6 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor domain ERM PF00769.14 KXX83425.1 - 1.4 8.4 54.8 0.027 14.0 12.2 3.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family UQ_con PF00179.21 KXX83426.1 - 7.6e-52 174.4 0.0 8.6e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KXX83426.1 - 8.5e-07 28.7 0.0 9.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KXX83426.1 - 0.026 14.3 0.2 0.054 13.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain CD99L2 PF12301.3 KXX83427.1 - 0.0093 15.6 0.1 0.052 13.2 0.0 2.0 2 0 0 2 2 2 1 CD99 antigen like protein 2 Sigma_reg_N PF13800.1 KXX83427.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Ribosomal_L33 PF00471.15 KXX83428.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L33 Aminotran_1_2 PF00155.16 KXX83429.1 - 9.4e-38 130.0 0.0 1.3e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Spherulin4 PF12138.3 KXX83429.1 - 0.1 12.0 0.0 0.22 10.8 0.0 1.5 1 1 0 1 1 1 0 Spherulation-specific family 4 RPN7 PF10602.4 KXX83430.1 - 9.7e-57 191.1 1.5 1.4e-56 190.6 0.3 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KXX83430.1 - 1.1e-13 51.3 0.0 2.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 KXX83430.1 - 0.19 12.4 2.1 2 9.3 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Med13_C PF06333.7 KXX83431.1 - 4.2e-116 387.9 0.0 1.1e-115 386.5 0.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KXX83431.1 - 5.4e-56 190.0 0.0 8.3e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 KXX83432.1 - 4.2e-13 48.6 0.9 8e-13 47.7 0.6 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KXX83432.1 - 0.026 14.4 0.0 23 5.0 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KXX83433.1 - 3e-24 85.8 0.0 4.2e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Pyridox_oxidase PF01243.15 KXX83434.1 - 1.4e-06 28.2 0.0 6.3e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase PRK PF00485.13 KXX83435.1 - 0.11 12.0 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Nop14 PF04147.7 KXX83435.1 - 0.25 9.2 19.9 0.45 8.3 13.8 1.3 1 0 0 1 1 1 0 Nop14-like family Chromo PF00385.19 KXX83436.1 - 2.4e-13 49.5 0.9 2.4e-13 49.5 0.6 2.5 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KXX83436.1 - 1.4e-12 47.2 0.1 1.1e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain MIP-T3 PF10243.4 KXX83436.1 - 0.0095 14.4 10.6 0.012 14.0 7.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DNA_pol_phi PF04931.8 KXX83436.1 - 0.15 9.7 17.5 0.21 9.3 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3449 PF11931.3 KXX83436.1 - 6 6.3 10.1 22 4.4 7.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) COPI_C PF06957.6 KXX83436.1 - 9.6 4.6 9.5 14 4.1 6.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus MFS_1 PF07690.11 KXX83437.1 - 1.1e-17 63.7 34.0 3.7e-15 55.4 6.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.8 KXX83437.1 - 8.9e-09 34.9 3.4 8.9e-09 34.9 2.3 1.8 2 0 0 2 2 2 1 Nodulin-like LCM PF04072.9 KXX83438.1 - 9.9e-26 90.4 0.0 1.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase MCM PF00493.18 KXX83439.1 - 4.8e-131 436.4 0.5 6.7e-131 436.0 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KXX83439.1 - 2.7e-17 63.3 0.1 2.2e-16 60.4 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KXX83439.1 - 2.7e-07 29.9 0.0 3.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KXX83439.1 - 0.003 17.1 0.0 0.0074 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KXX83439.1 - 0.0092 15.4 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF3801 PF12687.2 KXX83439.1 - 0.34 10.4 4.1 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF572 PF04502.8 KXX83439.1 - 1.7 7.7 12.8 3.3 6.8 8.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) CAP_N PF01213.14 KXX83440.1 - 2.7e-87 292.9 13.5 1.1e-86 290.9 9.4 1.8 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KXX83440.1 - 1.3e-54 183.8 1.5 1.8e-54 183.3 1.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KXX83440.1 - 0.25 10.7 1.1 0.57 9.5 0.7 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C DUF2433 PF10360.4 KXX83441.1 - 3.1e-55 186.0 0.0 4.8e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KXX83441.1 - 0.00012 22.3 6.3 0.0035 17.6 4.4 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 KXX83441.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KXX83441.1 - 0.021 14.2 0.0 0.047 13.0 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase PRCC PF10253.4 KXX83441.1 - 0.29 11.7 2.7 0.68 10.5 1.9 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PAT1 PF09770.4 KXX83441.1 - 5.5 5.1 10.4 8.1 4.5 7.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KXX83442.1 - 5.3e-37 127.1 0.0 1e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dna2 PF08696.6 KXX83442.1 - 0.013 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 E1_dh PF00676.15 KXX83443.1 - 3.6e-87 291.8 0.0 4.5e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KXX83443.1 - 0.0019 17.8 0.0 0.018 14.6 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transposase_22 PF02994.9 KXX83443.1 - 0.034 12.6 0.1 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 L1 transposable element SGS PF05002.10 KXX83443.1 - 0.14 11.9 2.2 1.2 8.9 0.4 2.5 2 1 0 2 2 2 0 SGS domain DXP_synthase_N PF13292.1 KXX83443.1 - 0.17 10.7 0.0 0.59 9.0 0.0 1.8 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.13 KXX83444.1 - 4.1e-69 232.2 0.0 5.4e-42 143.4 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KXX83444.1 - 1.5e-10 40.8 0.0 2.7e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KXX83444.1 - 4.1e-10 40.0 0.0 1.3e-05 25.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 KXX83444.1 - 1.2e-08 35.3 0.0 2.7e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KXX83444.1 - 7e-08 32.3 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KXX83444.1 - 1.9e-07 31.3 0.0 8.7e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KXX83444.1 - 1.4e-05 25.5 0.0 3.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KXX83444.1 - 0.0001 22.3 0.1 0.00029 20.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KXX83444.1 - 0.099 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF1237 PF06824.6 KXX83445.1 - 2.8e-181 602.7 0.0 3.3e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) FAA_hydrolase PF01557.13 KXX83446.1 - 2.6e-50 170.8 0.0 3.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PigN PF04987.9 KXX83447.1 - 2.3e-168 560.4 25.0 2.9e-168 560.0 17.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KXX83447.1 - 2.7e-11 43.4 0.6 3e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KXX83447.1 - 4.7e-07 29.2 0.1 8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KXX83447.1 - 0.00055 19.3 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CDC27 PF09507.5 KXX83448.1 - 4.5e-73 246.9 35.1 2e-72 244.7 24.3 1.9 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Nop14 PF04147.7 KXX83448.1 - 0.082 10.8 16.2 0.11 10.3 11.2 1.2 1 0 0 1 1 1 0 Nop14-like family K_channel_TID PF07941.6 KXX83448.1 - 0.084 13.1 2.4 0.23 11.7 1.6 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CDC45 PF02724.9 KXX83448.1 - 1.4 6.9 12.2 2 6.3 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 KXX83448.1 - 2.6 6.7 7.1 4.7 5.9 4.9 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 KXX83448.1 - 6.5 5.9 9.8 9.6 5.3 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein CytochromB561_N PF09786.4 KXX83448.1 - 6.8 5.0 7.9 9.7 4.5 5.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Exo70 PF03081.10 KXX83449.1 - 7.4e-69 232.3 0.0 1.3e-68 231.5 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit eIF-3c_N PF05470.7 KXX83449.1 - 0.057 11.4 0.0 0.11 10.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Syntaxin PF00804.20 KXX83449.1 - 0.93 9.6 7.0 7.3 6.8 0.2 3.5 3 0 0 3 3 3 0 Syntaxin Apolipoprotein PF01442.13 KXX83449.1 - 1 8.8 5.6 0.6 9.5 0.1 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KXX83449.1 - 2.4 7.9 7.1 40 4.0 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Aminotran_3 PF00202.16 KXX83450.1 - 1.4e-82 277.2 0.0 1.7e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KXX83450.1 - 6.5e-06 25.3 0.0 1.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II PNP_UDP_1 PF01048.15 KXX83451.1 - 1.9e-38 131.7 1.9 2.3e-38 131.5 1.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Atx10homo_assoc PF09759.4 KXX83452.1 - 4.4e-10 39.2 0.0 1.4e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Zip PF02535.17 KXX83452.1 - 0.09 11.7 11.3 0.029 13.3 4.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter KH_1 PF00013.24 KXX83453.1 - 1.5e-85 280.7 36.2 1.8e-12 46.7 0.4 11.9 12 1 0 12 12 12 9 KH domain KH_3 PF13014.1 KXX83453.1 - 3.5e-61 202.0 23.4 6.6e-10 38.4 0.1 11.2 10 0 0 10 10 10 9 KH domain SLS PF14611.1 KXX83453.1 - 1.2e-12 47.7 9.1 0.003 17.0 0.0 7.5 4 1 3 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KXX83453.1 - 6.5e-11 41.6 24.8 0.00076 18.9 0.1 8.1 7 2 0 8 8 8 4 KH domain BMC PF00936.14 KXX83453.1 - 2.6e-05 23.7 1.3 4.1 7.1 0.0 6.0 6 0 0 6 6 6 1 BMC domain Acylphosphatase PF00708.13 KXX83453.1 - 0.065 13.3 9.8 3.9 7.6 0.2 5.0 5 0 0 5 5 5 0 Acylphosphatase KH_4 PF13083.1 KXX83453.1 - 0.69 9.5 12.3 0.24 11.0 0.1 5.3 6 0 0 6 6 6 0 KH domain Pkinase PF00069.20 KXX83454.1 - 5e-71 238.9 0.0 7.9e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KXX83454.1 - 1.6e-45 155.2 0.0 2.7e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KXX83454.1 - 7.8e-17 61.4 0.0 3.1e-16 59.5 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KXX83454.1 - 5.2e-08 32.1 0.0 8.8e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KXX83454.1 - 0.0054 16.4 0.3 0.11 12.2 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KXX83454.1 - 0.11 11.5 0.0 0.46 9.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 KXX83454.1 - 0.19 10.9 0.0 0.45 9.7 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain adh_short PF00106.20 KXX83455.1 - 4.4e-30 104.7 1.3 6.5e-30 104.2 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KXX83455.1 - 3.5e-27 95.7 0.2 4.7e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KXX83455.1 - 6.3e-11 42.2 0.3 9.7e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KXX83455.1 - 1.7e-05 24.4 0.2 5.1e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KXX83455.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KXX83455.1 - 0.022 13.4 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Oxidored_nitro PF00148.14 KXX83455.1 - 0.025 13.2 0.1 0.038 12.6 0.1 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase PA PF02225.17 KXX83455.1 - 0.044 13.4 0.8 0.12 12.0 0.2 2.0 2 0 0 2 2 2 0 PA domain SelR PF01641.13 KXX83456.1 - 2.7e-40 136.9 0.5 1.1e-39 134.9 0.3 1.7 1 1 0 1 1 1 1 SelR domain DZR PF12773.2 KXX83456.1 - 0.07 12.9 2.3 4 7.3 0.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 KXX83456.1 - 0.11 12.6 0.2 0.24 11.4 0.2 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 KXX83456.1 - 0.14 12.0 0.7 3.4 7.6 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 KXX83456.1 - 0.33 10.8 3.8 4.2 7.3 0.3 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.6 KXX83456.1 - 2.1 7.9 7.9 4.6 6.8 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Carn_acyltransf PF00755.15 KXX83457.1 - 5.8e-175 582.7 0.0 7.3e-175 582.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM PF04433.12 KXX83458.1 - 1.5e-35 121.1 0.1 2.9e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KXX83458.1 - 8.6e-08 32.1 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KXX83458.1 - 4.2e-05 23.5 0.6 8.7e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KXX83458.1 - 0.036 13.6 3.1 0.071 12.6 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF3439 PF11921.3 KXX83458.1 - 0.099 12.3 5.0 0.23 11.2 3.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 KXX83458.1 - 0.32 8.9 7.3 0.45 8.4 5.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ETF PF01012.16 KXX83459.1 - 3.2e-41 140.7 0.6 5.8e-41 139.9 0.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KXX83459.1 - 6.7e-37 124.9 0.4 1.5e-36 123.8 0.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.9 KXX83460.1 - 6.9e-06 26.0 0.0 0.13 12.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KXX83460.1 - 4.5e-05 23.6 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KXX83460.1 - 0.0032 17.4 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KXX83460.1 - 0.063 11.7 0.0 0.12 10.7 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein AMP-binding PF00501.23 KXX83462.1 - 1e-78 264.6 0.0 1.4e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3295 PF11702.3 KXX83463.1 - 1.8e-169 564.9 33.9 2.1e-169 564.7 23.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KXX83463.1 - 5.2e-13 48.3 2.2 1.2e-12 47.1 1.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RTA1 PF04479.8 KXX83464.1 - 7.6e-38 130.2 5.0 7.6e-38 130.2 3.4 1.3 1 1 0 1 1 1 1 RTA1 like protein VHS PF00790.14 KXX83465.1 - 6.2e-43 145.8 2.2 5.1e-42 142.8 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KXX83465.1 - 1.4e-15 56.9 4.1 2.9e-15 55.9 2.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KXX83465.1 - 0.00019 20.7 14.4 0.0088 15.5 0.5 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KXX83465.1 - 0.0012 18.2 9.2 0.0026 17.1 1.2 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase Dioxygenase_C PF00775.16 KXX83466.1 - 1.4e-47 161.3 0.0 1.7e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KXX83466.1 - 1.2e-11 44.4 0.1 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KXX83466.1 - 0.01 15.9 0.0 0.029 14.4 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Complex1_30kDa PF00329.14 KXX83467.1 - 1.1e-35 121.9 0.0 1.8e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit GMC_oxred_N PF00732.14 KXX83468.1 - 8.9e-65 218.7 0.1 1.4e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KXX83468.1 - 7.5e-38 130.0 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KXX83468.1 - 1.2e-06 27.7 0.1 0.0084 14.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KXX83468.1 - 0.0002 21.7 0.6 0.77 10.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KXX83468.1 - 0.00075 18.5 5.3 0.024 13.5 3.8 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KXX83468.1 - 0.002 18.1 0.1 0.0077 16.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KXX83468.1 - 0.016 14.1 0.1 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KXX83468.1 - 0.029 13.4 0.4 0.061 12.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.13 KXX83468.1 - 0.2 11.6 1.0 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Tht1 PF04163.7 KXX83470.1 - 2.8e-05 22.7 5.0 0.00014 20.4 3.5 2.1 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF3829 PF12889.2 KXX83470.1 - 0.015 14.4 0.7 0.025 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF848 PF05852.6 KXX83470.1 - 0.02 14.7 1.6 0.02 14.7 1.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Fzo_mitofusin PF04799.8 KXX83470.1 - 0.024 14.0 0.6 0.024 14.0 0.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region CAP_N PF01213.14 KXX83470.1 - 0.024 13.9 2.8 0.44 9.7 0.6 2.2 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AAA_13 PF13166.1 KXX83470.1 - 0.085 11.3 6.5 0.11 10.8 4.5 1.1 1 0 0 1 1 1 0 AAA domain DUF2450 PF10475.4 KXX83470.1 - 0.088 11.7 2.3 0.17 10.7 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) NPV_P10 PF05531.7 KXX83470.1 - 0.14 12.4 7.9 0.31 11.3 0.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DegS PF05384.6 KXX83470.1 - 0.15 11.2 5.2 0.42 9.8 0.6 2.4 2 1 0 2 2 2 0 Sensor protein DegS Lyase_8_N PF08124.6 KXX83470.1 - 0.21 10.3 1.8 0.54 9.0 0.2 2.0 1 1 1 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ISG65-75 PF11727.3 KXX83470.1 - 0.34 9.9 2.8 0.31 10.0 0.8 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF972 PF06156.8 KXX83470.1 - 0.38 11.1 8.3 0.16 12.3 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) zf-C4H2 PF10146.4 KXX83470.1 - 0.74 9.7 5.1 0.76 9.7 1.8 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein Atg14 PF10186.4 KXX83470.1 - 0.89 8.4 12.8 0.086 11.7 3.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KXX83470.1 - 2 8.2 12.7 2.6 7.8 1.2 2.5 1 1 2 3 3 3 0 Tropomyosin like HAUS6_N PF14661.1 KXX83470.1 - 2.5 7.3 8.2 1.9 7.8 1.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1451 PF07295.6 KXX83470.1 - 3.8 7.2 9.5 1.9 8.2 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Lactonase PF10282.4 KXX83471.1 - 9.7e-15 54.4 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Ion_trans_2 PF07885.11 KXX83472.1 - 2.9e-34 116.6 25.2 6.5e-19 67.4 1.3 3.0 3 0 0 3 3 3 2 Ion channel SieB PF14163.1 KXX83472.1 - 0.18 11.3 1.3 4.1 6.9 0.0 2.7 3 0 0 3 3 3 0 Superinfection exclusion protein B Inositol_P PF00459.20 KXX83474.1 - 4.9e-52 176.8 1.4 8e-52 176.1 1.0 1.2 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 KXX83475.1 - 5.4e-23 81.2 0.0 8.8e-12 45.3 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L6 DUF2781 PF10914.3 KXX83475.1 - 0.00012 21.9 0.1 0.00044 20.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) Clr5 PF14420.1 KXX83476.1 - 2.7e-18 65.5 4.0 3.5e-18 65.2 2.7 1.1 1 0 0 1 1 1 1 Clr5 domain FLO_LFY PF01698.11 KXX83476.1 - 0.011 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1560 PF07597.6 KXX83476.1 - 0.052 13.5 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) PEHE PF15275.1 KXX83476.1 - 0.068 13.6 0.2 0.092 13.2 0.1 1.2 1 0 0 1 1 1 0 PEHE domain DUF2458 PF10454.4 KXX83476.1 - 0.1 12.4 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Apolipoprotein PF01442.13 KXX83477.1 - 0.035 13.6 2.5 0.089 12.2 1.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PH PF00169.24 KXX83477.1 - 0.036 14.2 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF77 PF01910.12 KXX83477.1 - 0.048 13.3 0.2 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF77 Synaptobrevin PF00957.16 KXX83478.1 - 0.025 14.1 0.6 0.19 11.3 0.2 2.0 1 1 1 2 2 2 0 Synaptobrevin DUF500 PF04366.7 KXX83479.1 - 2.7e-42 143.1 0.2 5.7e-42 142.1 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KXX83479.1 - 1e-14 53.6 0.3 2.5e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KXX83479.1 - 1.3e-12 47.1 0.0 2.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KXX83479.1 - 1.4e-11 43.6 0.0 3.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PfkB PF00294.19 KXX83480.1 - 1e-14 54.4 0.7 2.1e-08 33.6 1.2 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase